locus-tag	class	description
CNX65_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CNX65_00010	COG0592	DNA-directed DNA polymerase activity
CNX65_00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CNX65_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CNX65_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CNX65_00055	COG2259	Doxx family
CNX65_00075	COG0705	Rhomboid family
CNX65_00090	COG3764	Sortase (surface protein transpeptidase)
CNX65_00110	COG2815	serine threonine protein kinase
CNX65_00110	COG0515	serine threonine protein kinase
CNX65_00115	COG0515	serine threonine protein kinase
CNX65_00120	COG0768	penicillin binding
CNX65_00135	COG1716	ATPase activity
CNX65_00140	COG1716	ATPase activity
CNX65_00170	COG1309	transcriptional regulator
CNX65_00180	COG2211	Major facilitator Superfamily
CNX65_00185	COG0300	oxidoreductase activity
CNX65_00210	COG3281	Trehalose synthase
CNX65_00240	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CNX65_00260	COG0405	Gamma-glutamyltransferase
CNX65_00290	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CNX65_00305	COG2226	methyltransferase
CNX65_00340	COG3275	phosphorelay sensor kinase activity
CNX65_00350	COG3279	Response regulator of the LytR AlgR family
CNX65_00360	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CNX65_00370	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CNX65_00385	COG0584	glycerophosphoryl diester phosphodiesterase
CNX65_00400	COG0653	protein targeting
CNX65_00415	COG1528	Iron-storage protein
CNX65_00465	COG1271	oxidase subunit
CNX65_00470	COG1294	oxidase, subunit
CNX65_00480	COG4988	ABC transporter
CNX65_00495	COG0454	-acetyltransferase
CNX65_00520	COG1131	(ABC) transporter
CNX65_00525	COG1725	Transcriptional regulator
CNX65_00550	COG1501	Belongs to the glycosyl hydrolase 31 family
CNX65_00570	COG0754	glutathionylspermidine amidase activity
CNX65_00575	COG3766	membrane
CNX65_00585	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CNX65_00605	COG0579	oxidoreductase
CNX65_00615	COG0561	phosphatase activity
CNX65_00625	COG0463	Glycosyl transferase, family 2
CNX65_00645	COG1216	Glycosyl transferase, family 2
CNX65_00665	COG1216	Glycosyl transferase, family 2
CNX65_00710	COG2234	aminopeptidase activity
CNX65_00720	COG0737	Belongs to the 5'-nucleotidase family
CNX65_00720	COG1525	nuclease
CNX65_00720	COG4085	toxin activity
CNX65_00740	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CNX65_00765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CNX65_00790	COG1686	Belongs to the peptidase S11 family
CNX65_00795	COG5295	Hep Hag repeat protein
CNX65_00795	COG4932	domain protein
CNX65_00840	COG0183	Belongs to the thiolase family
CNX65_00855	COG0287	Prephenate dehydrogenase
CNX65_00860	COG1473	amidohydrolase
CNX65_00930	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CNX65_00935	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CNX65_00960	COG3629	intracellular signal transduction
CNX65_00960	COG3903	Transcriptional regulator
CNX65_00965	COG0747	negative chemotaxis
CNX65_00980	COG0444	Belongs to the ABC transporter superfamily
CNX65_00985	COG4608	Belongs to the ABC transporter superfamily
CNX65_00995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CNX65_01025	COG1070	Carbohydrate kinase
CNX65_01045	COG1764	response to oxidative stress
CNX65_01055	COG0431	NADPH-dependent FMN reductase
CNX65_01100	COG1408	metallophosphoesterase
CNX65_01160	COG0673	inositol 2-dehydrogenase activity
CNX65_01175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CNX65_01185	COG0592	DNA-directed DNA polymerase activity
CNX65_01210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CNX65_01215	COG0494	nUDIX hydrolase
CNX65_01225	COG0596	Alpha beta hydrolase
CNX65_01235	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CNX65_01240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CNX65_01255	COG3844	kynureninase activity
CNX65_01265	COG1522	sequence-specific DNA binding
CNX65_01270	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CNX65_01275	COG1737	Transcriptional regulator
CNX65_01285	COG3876	Protein conserved in bacteria
CNX65_01290	COG1472	Belongs to the glycosyl hydrolase 3 family
CNX65_01460	COG1111	helicase
CNX65_01460	COG1205	dead DEAH box helicase
CNX65_01465	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CNX65_01500	COG1754	DNA topoisomerase type I activity
CNX65_01500	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CNX65_01510	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CNX65_01515	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CNX65_01535	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CNX65_01540	COG1120	ATPase activity
CNX65_01580	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CNX65_01595	COG0037	tRNA processing
CNX65_01610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CNX65_01615	COG0302	gtp cyclohydrolase
CNX65_01620	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CNX65_01625	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CNX65_01645	COG0649	NAD binding
CNX65_01670	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CNX65_01675	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CNX65_01680	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CNX65_01690	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CNX65_01700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_01705	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_01710	COG1120	ATPase activity
CNX65_01720	COG0542	response to heat
CNX65_01725	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CNX65_01735	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CNX65_01760	COG1194	a g-specific adenine glycosylase
CNX65_01775	COG1609	Transcriptional regulator
CNX65_01785	COG1653	transport
CNX65_01790	COG1175	transmembrane transport
CNX65_01795	COG3833	ABC-type maltose transport systems, permease component
CNX65_01810	COG1121	(ABC) transporter
CNX65_01815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CNX65_01820	COG3706	GGDEF domain
CNX65_01820	COG0745	RESPONSE REGULATOR receiver
CNX65_01850	COG0215	cysteine-tRNA ligase activity
CNX65_01860	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CNX65_01865	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CNX65_01870	COG1329	Transcriptional regulator
CNX65_01890	COG4221	oxidoreductase activity
CNX65_01905	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CNX65_01940	COG2205	protein histidine kinase activity
CNX65_01945	COG0745	RESPONSE REGULATOR receiver
CNX65_01975	COG3903	Transcriptional regulator
CNX65_01975	COG3629	intracellular signal transduction
CNX65_01995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNX65_02000	COG0583	DNA-binding transcription factor activity
CNX65_02015	COG1404	Belongs to the peptidase S8 family
CNX65_02020	COG0179	Fumarylacetoacetate (FAA) hydrolase
CNX65_02025	COG4948	Mandelate Racemase Muconate Lactonizing
CNX65_02030	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_02050	COG2186	Transcriptional regulator
CNX65_02055	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CNX65_02065	COG1175	transmembrane transport
CNX65_02075	COG2188	Transcriptional regulator
CNX65_02080	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CNX65_02085	COG3384	dioxygenase
CNX65_02090	COG0352	thiamine-phosphate diphosphorylase activity
CNX65_02105	COG2022	thiamine diphosphate biosynthetic process
CNX65_02115	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CNX65_02120	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_02150	COG0351	phosphomethylpyrimidine kinase
CNX65_02155	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CNX65_02180	COG1802	Transcriptional regulator
CNX65_02185	COG1902	pentaerythritol trinitrate reductase activity
CNX65_02190	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CNX65_02210	COG0688	phosphatidylethanolamine metabolic process
CNX65_02230	COG1278	Cold shock
CNX65_02240	COG0459	protein refolding
CNX65_02260	COG3142	Participates in the control of copper homeostasis
CNX65_02280	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CNX65_02295	COG4948	Mandelate Racemase Muconate Lactonizing
CNX65_02330	COG2018	Roadblock/LC7 domain
CNX65_02370	COG0521	Mo-molybdopterin cofactor biosynthetic process
CNX65_02370	COG0315	cyclic pyranopterin monophosphate synthase activity
CNX65_02380	COG1388	LysM domain
CNX65_02390	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CNX65_02395	COG1846	Transcriptional regulator
CNX65_02420	COG3304	Inner membrane component domain
CNX65_02450	COG1278	Cold shock
CNX65_02460	COG2814	Major facilitator Superfamily
CNX65_02485	COG2252	PERMEase
CNX65_02495	COG2814	Major facilitator Superfamily
CNX65_02510	COG0488	(ABC) transporter
CNX65_02525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CNX65_02535	COG0823	Involved in the tonB-independent uptake of proteins
CNX65_02535	COG1506	peptidase
CNX65_02550	COG0259	pyridoxamine-phosphate oxidase activity
CNX65_02555	COG0829	nickel cation binding
CNX65_02565	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CNX65_02575	COG0804	urea catabolic process
CNX65_02580	COG0832	Belongs to the urease beta subunit family
CNX65_02585	COG0831	urea catabolic process
CNX65_02610	COG2197	response regulator
CNX65_02640	COG1132	(ABC) transporter
CNX65_02645	COG1132	(ABC) transporter
CNX65_02650	COG0531	amino acid
CNX65_02655	COG2017	converts alpha-aldose to the beta-anomer
CNX65_02660	COG1228	amidohydrolase
CNX65_02665	COG1960	acyl-CoA dehydrogenase activity
CNX65_02685	COG0415	Belongs to the DNA photolyase family
CNX65_02690	COG2197	response regulator
CNX65_02700	COG1668	transmembrane transport
CNX65_02705	COG4152	abc transporter atp-binding protein
CNX65_02735	COG0402	S-adenosylhomocysteine deaminase activity
CNX65_02740	COG2130	NADP-dependent
CNX65_02755	COG1674	ftsk spoiiie
CNX65_02790	COG2267	carboxylic ester hydrolase activity
CNX65_02795	COG0583	DNA-binding transcription factor activity
CNX65_02800	COG0384	phenazine biosynthesis protein PhzF
CNX65_02810	COG0702	epimerase
CNX65_02815	COG1733	regulation of RNA biosynthetic process
CNX65_02855	COG2197	response regulator
CNX65_02865	COG2319	Wd-40 repeat
CNX65_02865	COG4249	Peptidase C14 caspase catalytic subunit p20
CNX65_02910	COG3209	COG3209 Rhs family protein
CNX65_02985	COG2197	response regulator
CNX65_02990	COG3447	MASE1 domain protein
CNX65_02990	COG5002	protein histidine kinase activity
CNX65_02990	COG5001	Diguanylate cyclase
CNX65_02995	COG0778	Nitroreductase
CNX65_03000	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CNX65_03005	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CNX65_03015	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CNX65_03020	COG0588	phosphoglycerate mutase activity
CNX65_03045	COG2205	protein histidine kinase activity
CNX65_03075	COG1349	DNA-binding transcription factor activity
CNX65_03085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CNX65_03090	COG0521	Mo-molybdopterin cofactor biosynthetic process
CNX65_03090	COG0315	cyclic pyranopterin monophosphate synthase activity
CNX65_03095	COG1970	mechanosensitive ion channel activity
CNX65_03110	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CNX65_03115	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CNX65_03125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CNX65_03145	COG0515	serine threonine protein kinase
CNX65_03170	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CNX65_03175	COG0084	hydrolase, TatD family'
CNX65_03180	COG3583	domain protein
CNX65_03185	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CNX65_03190	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CNX65_03195	COG2011	ABC-type metal ion transport system permease component
CNX65_03205	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CNX65_03210	COG0488	(ABC) transporter
CNX65_03235	COG0318	PFAM AMP-dependent synthetase and ligase
CNX65_03240	COG0193	aminoacyl-tRNA hydrolase activity
CNX65_03260	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CNX65_03265	COG3706	GGDEF domain
CNX65_03265	COG0745	RESPONSE REGULATOR receiver
CNX65_03285	COG1309	transcriptional regulator
CNX65_03295	COG2133	pyrroloquinoline quinone binding
CNX65_03315	COG3956	TIGRFAM MazG family protein
CNX65_03320	COG4946	Tricorn protease homolog
CNX65_03320	COG0793	Belongs to the peptidase S41A family
CNX65_03335	COG0148	phosphopyruvate hydratase activity
CNX65_03375	COG4166	transmembrane transport
CNX65_03395	COG4608	Belongs to the ABC transporter superfamily
CNX65_03420	COG0714	Associated with various cellular activities
CNX65_03490	COG0183	Belongs to the thiolase family
CNX65_03520	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CNX65_03530	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CNX65_03540	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CNX65_03555	COG1331	Highly conserved protein containing a thioredoxin domain
CNX65_03580	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CNX65_03590	COG1793	dna ligase
CNX65_03595	COG0114	fumarate hydratase activity
CNX65_03600	COG0492	ferredoxin-NADP+ reductase activity
CNX65_03620	COG1722	exodeoxyribonuclease VII activity
CNX65_03630	COG1570	exodeoxyribonuclease VII activity
CNX65_03660	COG0419	ATPase involved in DNA repair
CNX65_03675	COG0012	GTP binding
CNX65_03685	COG1051	belongs to the nudix hydrolase family
CNX65_03690	COG2154	pterin-4-alpha-carbinolamine dehydratase
CNX65_03700	COG4149	molybdate abc transporter
CNX65_03705	COG3842	ATPase activity
CNX65_03720	COG1131	(ABC) transporter
CNX65_03740	COG0494	nUDIX hydrolase
CNX65_03745	COG0180	Tryptophanyl-tRNA synthetase
CNX65_03760	COG0747	negative chemotaxis
CNX65_03765	COG4166	transmembrane transport
CNX65_03785	COG4608	Belongs to the ABC transporter superfamily
CNX65_03790	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CNX65_03825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CNX65_03830	COG1611	Belongs to the LOG family
CNX65_03835	COG1611	Belongs to the LOG family
CNX65_03845	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CNX65_03865	COG0519	Catalyzes the synthesis of GMP from XMP
CNX65_03890	COG1024	Enoyl-CoA hydratase
CNX65_03895	COG3327	negative regulation of DNA-templated transcription, initiation
CNX65_03905	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CNX65_03915	COG2814	Major facilitator Superfamily
CNX65_03930	COG0297	glycogen (starch) synthase activity
CNX65_03935	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CNX65_03955	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CNX65_03975	COG2239	Acts as a magnesium transporter
CNX65_04020	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_04040	COG0598	Magnesium transport protein CorA
CNX65_04075	COG0513	Belongs to the DEAD box helicase family
CNX65_04130	COG0243	molybdopterin cofactor binding
CNX65_04135	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CNX65_04140	COG2223	nitrite transmembrane transporter activity
CNX65_04145	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CNX65_04145	COG2146	nitrite reductase [NAD(P)H] activity
CNX65_04150	COG2146	nitrite reductase [NAD(P)H] activity
CNX65_04150	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CNX65_04170	COG0745	RESPONSE REGULATOR receiver
CNX65_04190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CNX65_04215	COG0210	DNA helicase
CNX65_04230	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_04235	COG0583	DNA-binding transcription factor activity
CNX65_04275	COG0612	Peptidase, M16
CNX65_04285	COG1940	carbohydrate kinase activity
CNX65_04285	COG1846	Transcriptional regulator
CNX65_04315	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CNX65_04355	COG0406	alpha-ribazole phosphatase activity
CNX65_04355	COG0328	RNA-DNA hybrid ribonuclease activity
CNX65_04360	COG0431	NADPH-dependent FMN reductase
CNX65_04400	COG0791	NLP P60 protein
CNX65_04420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CNX65_04440	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CNX65_04460	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CNX65_04460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CNX65_04465	COG0174	glutamine synthetase
CNX65_04495	COG1522	sequence-specific DNA binding
CNX65_04505	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CNX65_04505	COG0519	Catalyzes the synthesis of GMP from XMP
CNX65_04520	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CNX65_04595	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CNX65_04625	COG1615	UPF0182 protein
CNX65_04655	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CNX65_04660	COG2884	Cell division ATP-binding protein ftsE
CNX65_04665	COG2177	Part of the ABC transporter FtsEX involved in
CNX65_04670	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CNX65_04675	COG2197	response regulator
CNX65_04680	COG4585	Histidine kinase
CNX65_04700	COG1643	Atp-dependent helicase
CNX65_04710	COG0456	acetyltransferase
CNX65_04710	COG0454	-acetyltransferase
CNX65_04715	COG2814	Major facilitator Superfamily
CNX65_04725	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CNX65_04785	COG1469	GTP cyclohydrolase I activity
CNX65_04790	COG0720	synthase
CNX65_04795	COG0602	queuosine metabolic process
CNX65_04800	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CNX65_04855	COG0514	ATP-dependent DNA helicase (RecQ)
CNX65_04860	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CNX65_04860	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CNX65_04890	COG1175	transmembrane transport
CNX65_04895	COG0395	ABC-type sugar transport system, permease component
CNX65_04910	COG1609	Transcriptional regulator
CNX65_04915	COG3903	Transcriptional regulator
CNX65_04915	COG3629	intracellular signal transduction
CNX65_04945	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CNX65_04950	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CNX65_04955	COG0235	Class ii aldolase
CNX65_04960	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CNX65_04970	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CNX65_04975	COG3830	Belongs to the UPF0237 family
CNX65_04975	COG0560	Phosphoserine phosphatase
CNX65_05030	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CNX65_05040	COG1335	isochorismatase
CNX65_05045	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CNX65_05085	COG1234	tRNA 3'-trailer cleavage
CNX65_05090	COG3386	PFAM SMP-30 Gluconolaconase
CNX65_05100	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CNX65_05105	COG1234	tRNA 3'-trailer cleavage
CNX65_05125	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CNX65_05130	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CNX65_05150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNX65_05155	COG2072	flavoprotein involved in K transport
CNX65_05160	COG0586	Pfam SNARE associated Golgi protein
CNX65_05210	COG2949	membrane
CNX65_05215	COG1316	TRANSCRIPTIONal
CNX65_05230	COG4213	ABC transporter substrate-binding protein
CNX65_05240	COG1278	Cold shock
CNX65_05250	COG3345	alpha-galactosidase
CNX65_05260	COG4279	zinc finger
CNX65_05265	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CNX65_05305	COG1376	ErfK ybiS ycfS ynhG family protein
CNX65_05310	COG0488	(ABC) transporter
CNX65_05320	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CNX65_05330	COG4977	sequence-specific DNA binding
CNX65_05350	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CNX65_05350	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CNX65_05365	COG0318	PFAM AMP-dependent synthetase and ligase
CNX65_05375	COG1846	Transcriptional regulator
CNX65_05380	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CNX65_05395	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CNX65_05395	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CNX65_05430	COG4106	trans-aconitate 2-methyltransferase activity
CNX65_05435	COG0506	proline dehydrogenase activity
CNX65_05440	COG1012	belongs to the aldehyde dehydrogenase family
CNX65_05450	COG0706	membrane insertase activity
CNX65_05475	COG1012	belongs to the aldehyde dehydrogenase family
CNX65_05525	COG0740	serine-type endopeptidase activity
CNX65_05530	COG0740	serine-type endopeptidase activity
CNX65_05580	COG1609	Transcriptional regulator
CNX65_05585	COG2223	nitrite transmembrane transporter activity
CNX65_05595	COG3336	cytochrome c oxidase
CNX65_05630	COG2902	Dehydrogenase
CNX65_05655	COG0366	Alpha amylase catalytic
CNX65_05665	COG0668	transmembrane transport
CNX65_05670	COG1505	serine-type exopeptidase activity
CNX65_05690	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CNX65_05700	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CNX65_05730	COG4552	Acetyltransferase involved in intracellular survival and related
CNX65_05750	COG0583	DNA-binding transcription factor activity
CNX65_05755	COG0544	peptidyl-prolyl cis-trans isomerase activity
CNX65_05760	COG0740	serine-type endopeptidase activity
CNX65_05765	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CNX65_05780	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CNX65_05815	COG0525	valine-tRNA ligase activity
CNX65_05820	COG0285	dihydrofolate synthase activity
CNX65_05850	COG0105	UTP biosynthetic process
CNX65_05855	COG1131	(ABC) transporter
CNX65_05865	COG0842	Transport permease protein
CNX65_05920	COG1530	ribonuclease E activity
CNX65_05920	COG1530	ribonuclease E activity
CNX65_05925	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CNX65_05930	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CNX65_05935	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CNX65_05945	COG0477	Major facilitator Superfamily
CNX65_05960	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CNX65_05975	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CNX65_05980	COG0799	negative regulation of ribosome biogenesis
CNX65_05990	COG2755	lipolytic protein G-D-S-L family
CNX65_05995	COG1307	EDD domain protein, DegV family
CNX65_06000	COG1596	polysaccharide export
CNX65_06000	COG1555	photosystem II stabilization
CNX65_06005	COG0658	competence protein
CNX65_06005	COG2333	competence protein COMEC
CNX65_06025	COG0268	Binds directly to 16S ribosomal RNA
CNX65_06055	COG2308	Evidence 4 Homologs of previously reported genes of
CNX65_06065	COG1305	Transglutaminase-like
CNX65_06075	COG0481	GTPase activity
CNX65_06090	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CNX65_06110	COG0531	amino acid
CNX65_06120	COG0604	alcohol dehydrogenase
CNX65_06135	COG2732	(Barnase) inhibitor
CNX65_06150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CNX65_06155	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CNX65_06195	COG1420	regulation of RNA biosynthetic process
CNX65_06200	COG0484	heat shock protein binding
CNX65_06220	COG0596	Alpha beta hydrolase
CNX65_06225	COG0537	adenosine 5'-monophosphoramidase activity
CNX65_06240	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CNX65_06260	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CNX65_06265	COG1381	Involved in DNA repair and RecF pathway recombination
CNX65_06270	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CNX65_06285	COG0701	Predicted permease
CNX65_06310	COG0423	glycine-tRNA ligase activity
CNX65_06335	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CNX65_06345	COG3340	Belongs to the peptidase S51 family
CNX65_06350	COG1595	DNA-templated transcription, initiation
CNX65_06355	COG0358	DNA primase activity
CNX65_06385	COG0582	viral genome integration into host DNA
CNX65_06410	COG4106	trans-aconitate 2-methyltransferase activity
CNX65_06420	COG1733	regulation of RNA biosynthetic process
CNX65_06430	COG1316	TRANSCRIPTIONal
CNX65_06440	COG0726	polysaccharide deacetylase
CNX65_06450	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CNX65_06455	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CNX65_06460	COG5001	Diguanylate cyclase
CNX65_06475	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CNX65_06480	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CNX65_06490	COG2084	Dehydrogenase
CNX65_06525	COG1132	(ABC) transporter
CNX65_06530	COG1132	(ABC) transporter
CNX65_06540	COG0515	serine threonine protein kinase
CNX65_06555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CNX65_06560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CNX65_06580	COG3201	nicotinamide mononucleotide transporter
CNX65_06585	COG1653	transport
CNX65_06595	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CNX65_06635	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CNX65_06655	COG0321	lipoyl(octanoyl) transferase activity
CNX65_06670	COG0702	epimerase
CNX65_06685	COG0508	dehydrogenase complex catalyzes the overall conversion of
CNX65_06690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CNX65_06705	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CNX65_06715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CNX65_06720	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CNX65_06740	COG0667	Aldo Keto reductase
CNX65_06775	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CNX65_06785	COG0204	Acyl-transferase
CNX65_06785	COG0318	PFAM AMP-dependent synthetase and ligase
CNX65_06790	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CNX65_06805	COG1845	cytochrome c oxidase, subunit III
CNX65_06810	COG2010	Cytochrome c
CNX65_06820	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CNX65_06850	COG0438	transferase activity, transferring glycosyl groups
CNX65_06875	COG0003	Pfam Anion-transporting ATPase
CNX65_06885	COG1940	carbohydrate kinase activity
CNX65_06915	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CNX65_06950	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CNX65_06975	COG0442	prolyl-tRNA aminoacylation
CNX65_07010	COG1201	RNA secondary structure unwinding
CNX65_07020	COG0443	Heat shock 70 kDa protein
CNX65_07025	COG2814	Major facilitator Superfamily
CNX65_07040	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CNX65_07045	COG2137	regulation of response to DNA damage stimulus
CNX65_07055	COG0800	Aldolase
CNX65_07095	COG0789	Transcriptional regulator
CNX65_07105	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CNX65_07115	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CNX65_07125	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CNX65_07140	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CNX65_07145	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CNX65_07155	COG1196	nuclear chromosome segregation
CNX65_07165	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CNX65_07175	COG0642	Histidine kinase
CNX65_07180	COG0745	RESPONSE REGULATOR receiver
CNX65_07185	COG1126	abc transporter atp-binding protein
CNX65_07195	COG0765	amino acid transport
CNX65_07200	COG0765	amino acid transport
CNX65_07230	COG1515	deoxyribonuclease V activity
CNX65_07235	COG1486	melibiose metabolic process
CNX65_07240	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CNX65_07245	COG2936	dipeptidyl-peptidase activity
CNX65_07255	COG0823	Involved in the tonB-independent uptake of proteins
CNX65_07255	COG1506	peptidase
CNX65_07255	COG4946	Tricorn protease homolog
CNX65_07260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CNX65_07270	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CNX65_07290	COG0123	including yeast histone deacetylase and acetoin utilization protein
CNX65_07300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CNX65_07305	COG2188	Transcriptional regulator
CNX65_07325	COG1690	Belongs to the RtcB family
CNX65_07365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CNX65_07375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CNX65_07380	COG4948	Mandelate Racemase Muconate Lactonizing
CNX65_07410	COG1490	D-aminoacyl-tRNA deacylase activity
CNX65_07415	COG2890	protein-(glutamine-N5) methyltransferase activity
CNX65_07435	COG2313	pseudouridylate synthase activity
CNX65_07450	COG1061	Type III restriction enzyme res subunit
CNX65_07455	COG4213	ABC transporter substrate-binding protein
CNX65_07465	COG4214	carbohydrate transport
CNX65_07515	COG0756	dUTP diphosphatase activity
CNX65_07545	COG0569	domain protein
CNX65_07550	COG0531	amino acid
CNX65_07555	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CNX65_07560	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CNX65_07570	COG0745	RESPONSE REGULATOR receiver
CNX65_07575	COG2205	protein histidine kinase activity
CNX65_07665	COG1250	3-hydroxyacyl-CoA dehydrogenase
CNX65_07665	COG1024	Enoyl-CoA hydratase
CNX65_07690	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CNX65_07695	COG2197	response regulator
CNX65_07710	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CNX65_07725	COG1404	Belongs to the peptidase S8 family
CNX65_07730	COG1404	Belongs to the peptidase S8 family
CNX65_07745	COG3220	belongs to the UPF0276 family
CNX65_07780	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CNX65_07800	COG1960	acyl-CoA dehydrogenase activity
CNX65_07805	COG1960	acyl-CoA dehydrogenase activity
CNX65_07810	COG1793	dna ligase
CNX65_07810	COG3285	dna ligase
CNX65_07835	COG5006	permease, DMT superfamily
CNX65_07840	COG1793	dna ligase
CNX65_07860	COG0488	(ABC) transporter
CNX65_07870	COG2706	6-phosphogluconolactonase activity
CNX65_07875	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CNX65_07900	COG1316	TRANSCRIPTIONal
CNX65_07910	COG0671	phosphoesterase, PA-phosphatase related
CNX65_07920	COG0653	protein targeting
CNX65_07935	COG1960	acyl-CoA dehydrogenase activity
CNX65_07960	COG1309	transcriptional regulator
CNX65_08010	COG0475	glutathione-regulated potassium exporter activity
CNX65_08030	COG1160	GTP binding
CNX65_08035	COG2197	response regulator
CNX65_08060	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CNX65_08070	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CNX65_08075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CNX65_08085	COG0438	transferase activity, transferring glycosyl groups
CNX65_08095	COG1215	transferase activity, transferring glycosyl groups
CNX65_08115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CNX65_08130	COG1131	(ABC) transporter
CNX65_08140	COG2197	response regulator
CNX65_08155	COG3851	Histidine kinase
CNX65_08160	COG2197	response regulator
CNX65_08305	COG0328	RNA-DNA hybrid ribonuclease activity
CNX65_08320	COG3345	alpha-galactosidase
CNX65_08335	COG0410	ABC transporter
CNX65_08370	COG1940	carbohydrate kinase activity
CNX65_08390	COG0601	transmembrane transport
CNX65_08400	COG0444	Belongs to the ABC transporter superfamily
CNX65_08430	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CNX65_08435	COG2318	DinB family
CNX65_08440	COG2255	four-way junction helicase activity
CNX65_08445	COG0632	four-way junction helicase activity
CNX65_08470	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CNX65_08475	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CNX65_08480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CNX65_08495	COG0124	histidyl-tRNA synthetase
CNX65_08545	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CNX65_08580	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CNX65_08595	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CNX65_08600	COG2205	protein histidine kinase activity
CNX65_08605	COG0745	RESPONSE REGULATOR receiver
CNX65_08620	COG2372	response to copper ion
CNX65_08660	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CNX65_08675	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CNX65_08705	COG2244	polysaccharide biosynthetic process
CNX65_08760	COG2153	protein acetylation
CNX65_08790	COG0667	Aldo Keto reductase
CNX65_08795	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CNX65_08795	COG2226	methyltransferase
CNX65_08795	COG0596	Alpha beta hydrolase
CNX65_08800	COG1024	Enoyl-CoA hydratase
CNX65_08820	COG1295	ribonuclease BN
CNX65_08830	COG3547	Transposase (IS116 IS110 IS902 family)
CNX65_08840	COG1126	abc transporter atp-binding protein
CNX65_08845	COG0765	amino acid transport
CNX65_08855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CNX65_08890	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CNX65_08910	COG0395	ABC-type sugar transport system, permease component
CNX65_08915	COG2723	6-phospho-beta-galactosidase activity
CNX65_08925	COG4115	mRNA cleavage
CNX65_08930	COG2161	toxin-antitoxin pair type II binding
CNX65_08940	COG5416	Lipopolysaccharide assembly protein A domain
CNX65_08945	COG4249	Peptidase C14 caspase catalytic subunit p20
CNX65_08945	COG2319	Wd-40 repeat
CNX65_08950	COG1940	carbohydrate kinase activity
CNX65_08960	COG2115	Belongs to the xylose isomerase family
CNX65_08965	COG1070	Carbohydrate kinase
CNX65_08970	COG0655	NAD(P)H dehydrogenase (quinone) activity
CNX65_09000	COG2207	Transcriptional regulator
CNX65_09000	COG3708	Transcriptional regulator
CNX65_09050	COG0640	Transcriptional regulator
CNX65_09090	COG0791	NLP P60 protein
CNX65_09105	COG1609	Transcriptional regulator
CNX65_09110	COG1609	Transcriptional regulator
CNX65_09125	COG3458	cephalosporin-C deacetylase activity
CNX65_09180	COG0492	ferredoxin-NADP+ reductase activity
CNX65_09195	COG1609	Transcriptional regulator
CNX65_09205	COG4677	pectinesterase activity
CNX65_09215	COG0395	ABC-type sugar transport system, permease component
CNX65_09225	COG4948	Mandelate Racemase Muconate Lactonizing
CNX65_09255	COG1172	Belongs to the binding-protein-dependent transport system permease family
CNX65_09260	COG1172	Belongs to the binding-protein-dependent transport system permease family
CNX65_09270	COG1879	ABC-type sugar transport system periplasmic component
CNX65_09285	COG3940	Belongs to the glycosyl hydrolase 43 family
CNX65_09295	COG1609	Transcriptional regulator
CNX65_09310	COG2160	L-arabinose isomerase activity
CNX65_09325	COG4214	carbohydrate transport
CNX65_09335	COG3401	FG-GAP repeat protein
CNX65_09350	COG1609	Transcriptional regulator
CNX65_09375	COG2356	endonuclease I
CNX65_09385	COG4585	Histidine kinase
CNX65_09405	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CNX65_09410	COG4715	Zinc finger, swim domain protein
CNX65_09415	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CNX65_09430	COG0714	Associated with various cellular activities
CNX65_09435	COG3831	ATPase activity
CNX65_09440	COG3831	ATPase activity
CNX65_09450	COG0438	transferase activity, transferring glycosyl groups
CNX65_09475	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CNX65_09490	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CNX65_09495	COG2326	polyphosphate kinase activity
CNX65_09500	COG2261	transglycosylase associated protein
CNX65_09585	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CNX65_09590	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CNX65_09595	COG2815	serine threonine protein kinase
CNX65_09595	COG0515	serine threonine protein kinase
CNX65_09605	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CNX65_09605	COG2755	lipolytic protein G-D-S-L family
CNX65_09615	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CNX65_09635	COG1175	transmembrane transport
CNX65_09640	COG0395	ABC-type sugar transport system, permease component
CNX65_09650	COG0702	epimerase
CNX65_09660	COG0745	RESPONSE REGULATOR receiver
CNX65_09680	COG2197	response regulator
CNX65_09685	COG4585	Histidine kinase
CNX65_09695	COG1131	(ABC) transporter
CNX65_09795	COG2124	cytochrome p450
CNX65_09800	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CNX65_09820	COG1846	Transcriptional regulator
CNX65_09840	COG2197	response regulator
CNX65_09860	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CNX65_09860	COG4106	trans-aconitate 2-methyltransferase activity
CNX65_09890	COG0395	ABC-type sugar transport system, permease component
CNX65_09895	COG4209	transmembrane transport
CNX65_09905	COG1609	Transcriptional regulator
CNX65_09915	COG0542	response to heat
CNX65_09945	COG1011	Hydrolase
CNX65_09960	COG1295	ribonuclease BN
CNX65_09970	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CNX65_09975	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CNX65_09990	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CNX65_10000	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CNX65_10035	COG3851	Histidine kinase
CNX65_10040	COG2197	response regulator
CNX65_10055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CNX65_10085	COG1595	DNA-templated transcription, initiation
CNX65_10175	COG1660	Displays ATPase and GTPase activities
CNX65_10350	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CNX65_10415	COG2181	nitrate reductase activity
CNX65_10420	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CNX65_10425	COG1140	nitrate reductase beta subunit
CNX65_10480	COG1732	Glycine betaine
CNX65_10485	COG1174	glycine betaine transport
CNX65_10495	COG1174	glycine betaine transport
CNX65_10520	COG3842	ATPase activity
CNX65_10540	COG0590	tRNA wobble adenosine to inosine editing
CNX65_10550	COG3835	regulator
CNX65_10580	COG0492	ferredoxin-NADP+ reductase activity
CNX65_10590	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CNX65_10605	COG0531	amino acid
CNX65_10615	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CNX65_10630	COG2186	Transcriptional regulator
CNX65_10650	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CNX65_10670	COG1560	Kdo2-lipid A biosynthetic process
CNX65_10675	COG0438	transferase activity, transferring glycosyl groups
CNX65_10700	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CNX65_10710	COG1953	Uracil, thiamine, allantoin
CNX65_10745	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CNX65_10750	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CNX65_10755	COG0217	transcriptional regulatory protein
CNX65_10770	COG1309	transcriptional regulator
CNX65_10775	COG0477	Major facilitator Superfamily
CNX65_10785	COG2124	cytochrome p450
CNX65_10820	COG3572	ergothioneine biosynthetic process
CNX65_10825	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CNX65_10830	COG0121	glutamine amidotransferase
CNX65_10835	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CNX65_10880	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CNX65_10910	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CNX65_10920	COG0318	PFAM AMP-dependent synthetase and ligase
CNX65_10925	COG0791	NLP P60 protein
CNX65_10925	COG3883	PFAM NLP P60 protein
CNX65_10940	COG0746	molybdenum cofactor guanylyltransferase activity
CNX65_10945	COG0500	methyltransferase
CNX65_10950	COG0714	Associated with various cellular activities
CNX65_10975	COG5002	protein histidine kinase activity
CNX65_11055	COG3012	SEC-C Motif Domain Protein
CNX65_11065	COG4733	cellulase activity
CNX65_11065	COG5297	Belongs to the glycosyl hydrolase family 6
CNX65_11070	COG1472	Belongs to the glycosyl hydrolase 3 family
CNX65_11085	COG4209	transmembrane transport
CNX65_11090	COG0395	ABC-type sugar transport system, permease component
CNX65_11105	COG1324	tolerance protein
CNX65_11110	COG0789	Transcriptional regulator
CNX65_11125	COG0277	FAD linked oxidase domain protein
CNX65_11125	COG0247	lactate metabolic process
CNX65_11130	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_11135	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CNX65_11155	COG4221	oxidoreductase activity
CNX65_11180	COG5297	Belongs to the glycosyl hydrolase family 6
CNX65_11185	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
CNX65_11210	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CNX65_11215	COG0215	cysteine-tRNA ligase activity
CNX65_11245	COG0745	RESPONSE REGULATOR receiver
CNX65_11250	COG0745	RESPONSE REGULATOR receiver
CNX65_11255	COG5002	protein histidine kinase activity
CNX65_11265	COG1410	methionine synthase
CNX65_11265	COG0646	methionine synthase
CNX65_11270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CNX65_11290	COG0300	oxidoreductase activity
CNX65_11300	COG0140	phosphoribosyl-ATP diphosphatase activity
CNX65_11320	COG1994	Peptidase M50
CNX65_11320	COG0517	IMP dehydrogenase activity
CNX65_11325	COG2197	response regulator
CNX65_11355	COG1222	aaa ATPase
CNX65_11360	COG2197	response regulator
CNX65_11365	COG4585	Histidine kinase
CNX65_11405	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CNX65_11410	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CNX65_11415	COG4221	oxidoreductase activity
CNX65_11435	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CNX65_11455	COG2378	regulation of single-species biofilm formation
CNX65_11465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CNX65_11520	COG3706	GGDEF domain
CNX65_11545	COG2357	RelA SpoT domain protein
CNX65_11560	COG2353	YceI-like domain
CNX65_11565	COG1846	Transcriptional regulator
CNX65_11570	COG0714	Associated with various cellular activities
CNX65_11580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CNX65_11590	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CNX65_11590	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CNX65_11590	COG1703	isobutyryl-CoA mutase activity
CNX65_11605	COG0187	DNA topoisomerase II activity
CNX65_11635	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CNX65_11640	COG5001	Diguanylate cyclase
CNX65_11640	COG1716	ATPase activity
CNX65_11665	COG3845	ABC transporter
CNX65_11695	COG1940	carbohydrate kinase activity
CNX65_11700	COG0673	inositol 2-dehydrogenase activity
CNX65_11710	COG0277	FAD linked oxidase domain protein
CNX65_11760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNX65_11765	COG2205	protein histidine kinase activity
CNX65_11780	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CNX65_11790	COG0745	RESPONSE REGULATOR receiver
CNX65_11800	COG0745	RESPONSE REGULATOR receiver
CNX65_11810	COG2201	protein-glutamate methylesterase activity
CNX65_11825	COG0835	chemotaxis
CNX65_11830	COG2198	Histidine kinase
CNX65_11830	COG0643	Histidine kinase
CNX65_11860	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CNX65_11870	COG1987	bacterial-type flagellum assembly
CNX65_11875	COG1338	Plays a role in the flagellum-specific transport system
CNX65_11905	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CNX65_11915	COG4786	Flagellar basal body rod
CNX65_11930	COG0741	lytic transglycosylase activity
CNX65_11950	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CNX65_11955	COG1766	The M ring may be actively involved in energy transduction
CNX65_11960	COG1677	Flagellar hook-basal body complex protein FliE
CNX65_11965	COG1558	bacterial-type flagellum-dependent cell motility
CNX65_11980	COG1516	flagellar protein fliS
CNX65_11995	COG1191	sigma factor activity
CNX65_12005	COG4786	Flagellar basal body rod
CNX65_12005	COG1256	bacterial-type flagellum assembly
CNX65_12015	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CNX65_12020	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CNX65_12050	COG5002	protein histidine kinase activity
CNX65_12055	COG3852	Histidine kinase
CNX65_12060	COG2205	protein histidine kinase activity
CNX65_12060	COG0745	RESPONSE REGULATOR receiver
CNX65_12060	COG4191	Histidine kinase
CNX65_12070	COG2204	response regulator
CNX65_12100	COG1846	Transcriptional regulator
CNX65_12120	COG4251	negative regulation of phosphorylation
CNX65_12135	COG1522	sequence-specific DNA binding
CNX65_12140	COG2814	Major facilitator Superfamily
CNX65_12170	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_12180	COG0326	Molecular chaperone. Has ATPase activity
CNX65_12230	COG1609	Transcriptional regulator
CNX65_12240	COG1175	transmembrane transport
CNX65_12245	COG0395	ABC-type sugar transport system, permease component
CNX65_12285	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CNX65_12315	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_12340	COG0277	FAD linked oxidase domain protein
CNX65_12385	COG0420	3'-5' exonuclease activity
CNX65_12410	COG0604	alcohol dehydrogenase
CNX65_12410	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_12410	COG3321	synthase
CNX65_12430	COG2119	membrane
CNX65_12460	COG4172	Belongs to the ABC transporter superfamily
CNX65_12465	COG0747	negative chemotaxis
CNX65_12475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CNX65_12495	COG0745	RESPONSE REGULATOR receiver
CNX65_12500	COG2205	protein histidine kinase activity
CNX65_12520	COG1802	Transcriptional regulator
CNX65_12560	COG1335	isochorismatase
CNX65_12660	COG1819	glycosyl
CNX65_12665	COG1132	(ABC) transporter
CNX65_12695	COG3795	YCII-related domain
CNX65_12700	COG4941	Belongs to the sigma-70 factor family
CNX65_12745	COG0714	Associated with various cellular activities
CNX65_12750	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CNX65_12810	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CNX65_12820	COG0515	serine threonine protein kinase
CNX65_12840	COG2124	cytochrome p450
CNX65_12850	COG2814	Major facilitator Superfamily
CNX65_12860	COG4581	dead DEAH box helicase
CNX65_12900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CNX65_12915	COG0477	Major facilitator Superfamily
CNX65_12925	COG1612	heme a metabolic process
CNX65_12940	COG5001	Diguanylate cyclase
CNX65_12980	COG2205	protein histidine kinase activity
CNX65_12985	COG0745	RESPONSE REGULATOR receiver
CNX65_13060	COG0395	ABC-type sugar transport system, permease component
CNX65_13080	COG1609	Transcriptional regulator
CNX65_13095	COG1595	DNA-templated transcription, initiation
CNX65_13180	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CNX65_13185	COG0477	Major facilitator Superfamily
CNX65_13230	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_13235	COG1309	transcriptional regulator
CNX65_13240	COG3384	dioxygenase
CNX65_13245	COG0702	epimerase
CNX65_13275	COG0488	(ABC) transporter
CNX65_13285	COG0640	Transcriptional regulator
CNX65_13290	COG0346	lactoylglutathione lyase activity
CNX65_13320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNX65_13330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CNX65_13350	COG2205	protein histidine kinase activity
CNX65_13360	COG1253	flavin adenine dinucleotide binding
CNX65_13370	COG0604	alcohol dehydrogenase
CNX65_13380	COG2080	2 iron, 2 sulfur cluster binding
CNX65_13380	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CNX65_13420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CNX65_13430	COG2376	Dihydroxyacetone kinase
CNX65_13435	COG0698	ribose 5-phosphate isomerase
CNX65_13440	COG0149	triose-phosphate isomerase activity
CNX65_13445	COG1082	Xylose isomerase domain protein TIM barrel
CNX65_13450	COG2084	Dehydrogenase
CNX65_13490	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CNX65_13490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CNX65_13500	COG1834	amidinotransferase
CNX65_13515	COG0475	glutathione-regulated potassium exporter activity
CNX65_13520	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CNX65_13555	COG1131	(ABC) transporter
CNX65_13575	COG0477	Major facilitator Superfamily
CNX65_13600	COG2267	carboxylic ester hydrolase activity
CNX65_13615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CNX65_13635	COG1509	lysine 2,3-aminomutase activity
CNX65_13660	COG1136	(ABC) transporter
CNX65_13710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_13715	COG1120	ATPase activity
CNX65_13775	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CNX65_13790	COG1120	ATPase activity
CNX65_13795	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_13800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_13805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CNX65_13810	COG2375	cellular response to nickel ion
CNX65_13815	COG1535	isochorismatase
CNX65_13815	COG3433	isochorismatase activity
CNX65_13820	COG3433	isochorismatase activity
CNX65_13820	COG1535	isochorismatase
CNX65_13825	COG1021	2,3-dihydroxybenzoate-AMP ligase
CNX65_13830	COG1169	isochorismate synthase
CNX65_13840	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_13855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_13860	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CNX65_13875	COG3655	Transcriptional regulator
CNX65_13890	COG4585	Histidine kinase
CNX65_13895	COG2197	response regulator
CNX65_13905	COG0148	phosphopyruvate hydratase activity
CNX65_13920	COG4152	abc transporter atp-binding protein
CNX65_13925	COG1668	transmembrane transport
CNX65_13965	COG0477	Major facilitator Superfamily
CNX65_13975	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CNX65_13980	COG2197	response regulator
CNX65_13990	COG0577	efflux transmembrane transporter activity
CNX65_13990	COG1136	(ABC) transporter
CNX65_14050	COG1309	transcriptional regulator
CNX65_14055	COG1132	(ABC) transporter
CNX65_14070	COG0738	Major facilitator superfamily
CNX65_14085	COG0583	DNA-binding transcription factor activity
CNX65_14090	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CNX65_14100	COG1012	belongs to the aldehyde dehydrogenase family
CNX65_14120	COG2409	Drug exporters of the RND superfamily
CNX65_14130	COG2027	D-alanyl-D-alanine carboxypeptidase
CNX65_14140	COG0438	transferase activity, transferring glycosyl groups
CNX65_14210	COG2226	methyltransferase
CNX65_14235	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CNX65_14240	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CNX65_14255	COG1131	(ABC) transporter
CNX65_14265	COG0604	alcohol dehydrogenase
CNX65_14265	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_14265	COG3321	synthase
CNX65_14295	COG1653	transport
CNX65_14305	COG3833	ABC-type maltose transport systems, permease component
CNX65_14320	COG3507	Belongs to the glycosyl hydrolase 43 family
CNX65_14330	COG0596	Alpha beta hydrolase
CNX65_14345	COG2197	response regulator
CNX65_14365	COG0028	Belongs to the TPP enzyme family
CNX65_14370	COG1473	amidohydrolase
CNX65_14375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNX65_14390	COG1177	transmembrane transport
CNX65_14395	COG1176	ABC-type spermidine putrescine transport system, permease component I
CNX65_14400	COG3842	ATPase activity
CNX65_14410	COG4221	oxidoreductase activity
CNX65_14430	COG1309	transcriptional regulator
CNX65_14475	COG3209	COG3209 Rhs family protein
CNX65_14525	COG0135	phosphoribosylanthranilate isomerase activity
CNX65_14565	COG3903	Transcriptional regulator
CNX65_14565	COG3629	intracellular signal transduction
CNX65_14580	COG2076	Multidrug Resistance protein
CNX65_14625	COG0642	Histidine kinase
CNX65_14670	COG3831	ATPase activity
CNX65_14675	COG4251	negative regulation of phosphorylation
CNX65_14685	COG0784	Response regulator, receiver
CNX65_14705	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_14715	COG0395	ABC-type sugar transport system, permease component
CNX65_14735	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CNX65_14750	COG3629	intracellular signal transduction
CNX65_14750	COG3903	Transcriptional regulator
CNX65_14790	COG1222	aaa ATPase
CNX65_14880	COG3629	intracellular signal transduction
CNX65_14880	COG3903	Transcriptional regulator
CNX65_14925	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CNX65_14935	COG3831	ATPase activity
CNX65_14940	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CNX65_14975	COG0673	inositol 2-dehydrogenase activity
CNX65_14990	COG0494	nUDIX hydrolase
CNX65_15040	COG1501	Belongs to the glycosyl hydrolase 31 family
CNX65_15050	COG1609	Transcriptional regulator
CNX65_15085	COG4106	trans-aconitate 2-methyltransferase activity
CNX65_15105	COG2318	DinB family
CNX65_15120	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_15130	COG0789	Transcriptional regulator
CNX65_15135	COG2197	response regulator
CNX65_15140	COG4585	Histidine kinase
CNX65_15145	COG1136	(ABC) transporter
CNX65_15145	COG0577	efflux transmembrane transporter activity
CNX65_15200	COG2375	cellular response to nickel ion
CNX65_15205	COG3629	intracellular signal transduction
CNX65_15205	COG3903	Transcriptional regulator
CNX65_15230	COG3831	ATPase activity
CNX65_15265	COG0483	inositol monophosphate 1-phosphatase activity
CNX65_15275	COG1132	(ABC) transporter
CNX65_15315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CNX65_15320	COG0300	oxidoreductase activity
CNX65_15380	COG3973	AAA domain
CNX65_15415	COG1556	Lactate utilization protein
CNX65_15420	COG1139	Iron-sulfur cluster binding protein
CNX65_15425	COG0247	lactate metabolic process
CNX65_15430	COG2188	Transcriptional regulator
CNX65_15435	COG1609	Transcriptional regulator
CNX65_15440	COG1129	ABC transporter
CNX65_15450	COG1172	Belongs to the binding-protein-dependent transport system permease family
CNX65_15465	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_15465	COG3347	Dehydrogenase
CNX65_15470	COG1070	Carbohydrate kinase
CNX65_15480	COG0402	S-adenosylhomocysteine deaminase activity
CNX65_15495	COG0586	Pfam SNARE associated Golgi protein
CNX65_15500	COG4585	Histidine kinase
CNX65_15505	COG2197	response regulator
CNX65_15510	COG3851	Histidine kinase
CNX65_15560	COG5398	heme oxygenase
CNX65_15585	COG0601	transmembrane transport
CNX65_15590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CNX65_15595	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CNX65_15600	COG1136	(ABC) transporter
CNX65_15605	COG0367	asparagine synthase
CNX65_15625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CNX65_15635	COG1012	belongs to the aldehyde dehydrogenase family
CNX65_15685	COG0583	DNA-binding transcription factor activity
CNX65_15720	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CNX65_15725	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CNX65_15740	COG3345	alpha-galactosidase
CNX65_15755	COG0644	oxidoreductase
CNX65_15760	COG0156	8-amino-7-oxononanoate synthase activity
CNX65_15780	COG3629	intracellular signal transduction
CNX65_15780	COG3903	Transcriptional regulator
CNX65_15790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CNX65_15795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNX65_15825	COG0583	DNA-binding transcription factor activity
CNX65_15840	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CNX65_15855	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CNX65_15860	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CNX65_15870	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_15875	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CNX65_15880	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CNX65_15905	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CNX65_15910	COG0235	Class ii aldolase
CNX65_15915	COG1960	acyl-CoA dehydrogenase activity
CNX65_15920	COG0477	Major facilitator Superfamily
CNX65_15950	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_15995	COG1830	Aldolase
CNX65_16000	COG1063	alcohol dehydrogenase
CNX65_16010	COG0659	secondary active sulfate transmembrane transporter activity
CNX65_16035	COG1408	metallophosphoesterase
CNX65_16055	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CNX65_16055	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CNX65_16060	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CNX65_16070	COG2409	Drug exporters of the RND superfamily
CNX65_16085	COG1024	Enoyl-CoA hydratase
CNX65_16125	COG1132	(ABC) transporter
CNX65_16130	COG0475	glutathione-regulated potassium exporter activity
CNX65_16190	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CNX65_16205	COG1250	3-hydroxyacyl-CoA dehydrogenase
CNX65_16210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CNX65_16240	COG3795	YCII-related domain
CNX65_16260	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CNX65_16315	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_16330	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CNX65_16330	COG2124	cytochrome p450
CNX65_16380	COG3507	Belongs to the glycosyl hydrolase 43 family
CNX65_16415	COG4585	Histidine kinase
CNX65_16420	COG2197	response regulator
CNX65_16450	COG4221	oxidoreductase activity
CNX65_16455	COG0667	Aldo Keto reductase
CNX65_16475	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CNX65_16480	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CNX65_16530	COG0546	phosphoglycolate phosphatase activity
CNX65_16565	COG3509	depolymerase
CNX65_16565	COG3693	PFAM glycoside hydrolase, family 10
CNX65_16580	COG1609	Transcriptional regulator
CNX65_16595	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_16625	COG1073	alpha beta
CNX65_16640	COG0714	Associated with various cellular activities
CNX65_16735	COG3507	Belongs to the glycosyl hydrolase 43 family
CNX65_16750	COG1609	Transcriptional regulator
CNX65_16760	COG1733	regulation of RNA biosynthetic process
CNX65_16780	COG0596	Alpha beta hydrolase
CNX65_16820	COG2261	transglycosylase associated protein
CNX65_16830	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CNX65_16850	COG2197	response regulator
CNX65_16865	COG1064	alcohol dehydrogenase
CNX65_16870	COG1309	transcriptional regulator
CNX65_16880	COG1454	alcohol dehydrogenase
CNX65_16885	COG0126	phosphoglycerate kinase activity
CNX65_16890	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CNX65_16895	COG1063	alcohol dehydrogenase
CNX65_16900	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CNX65_16905	COG0259	pyridoxamine-phosphate oxidase activity
CNX65_16910	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CNX65_16925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CNX65_16935	COG0477	Major facilitator Superfamily
CNX65_16945	COG1063	alcohol dehydrogenase
CNX65_16950	COG0667	Aldo Keto reductase
CNX65_16965	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CNX65_16970	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CNX65_16980	COG0494	nUDIX hydrolase
CNX65_16985	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CNX65_16995	COG1335	isochorismatase
CNX65_17030	COG0318	PFAM AMP-dependent synthetase and ligase
CNX65_17030	COG0300	oxidoreductase activity
CNX65_17030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CNX65_17030	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_17030	COG3321	synthase
CNX65_17060	COG1132	(ABC) transporter
CNX65_17065	COG1132	(ABC) transporter
CNX65_17075	COG1725	Transcriptional regulator
CNX65_17110	COG0028	Belongs to the TPP enzyme family
CNX65_17140	COG3629	intracellular signal transduction
CNX65_17140	COG3903	Transcriptional regulator
CNX65_17175	COG2249	NAD(P)H dehydrogenase (quinone) activity
CNX65_17195	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CNX65_17200	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CNX65_17210	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CNX65_17225	COG1607	acyl-coa hydrolase
CNX65_17245	COG0463	Glycosyl transferase, family 2
CNX65_17270	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CNX65_17280	COG1435	thymidine kinase activity
CNX65_17310	COG3706	GGDEF domain
CNX65_17320	COG3467	pyridoxamine 5'-phosphate
CNX65_17330	COG2161	toxin-antitoxin pair type II binding
CNX65_17335	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CNX65_17360	COG2226	methyltransferase
CNX65_17365	COG0640	Transcriptional regulator
CNX65_17370	COG0798	PFAM Bile acid sodium symporter
CNX65_17385	COG0604	alcohol dehydrogenase
CNX65_17440	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_17460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CNX65_17465	COG1349	DNA-binding transcription factor activity
CNX65_17470	COG0494	nUDIX hydrolase
CNX65_17480	COG5002	protein histidine kinase activity
CNX65_17480	COG2176	DNA-directed DNA polymerase activity
CNX65_17530	COG1619	proteins homologs of microcin C7 resistance protein MccF
CNX65_17570	COG1960	acyl-CoA dehydrogenase activity
CNX65_17595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CNX65_17600	COG0601	transmembrane transport
CNX65_17605	COG0747	negative chemotaxis
CNX65_17615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CNX65_17630	COG1609	Transcriptional regulator
CNX65_17650	COG4974	Belongs to the 'phage' integrase family
CNX65_17675	COG0667	Aldo Keto reductase
CNX65_17690	COG1309	transcriptional regulator
CNX65_17725	COG2755	lipolytic protein G-D-S-L family
CNX65_17760	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CNX65_17775	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CNX65_17785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CNX65_17800	COG1846	Transcriptional regulator
CNX65_17830	COG1643	Atp-dependent helicase
CNX65_17850	COG1968	undecaprenyl-diphosphatase activity
CNX65_17855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNX65_17860	COG0667	Aldo Keto reductase
CNX65_17905	COG2909	trisaccharide binding
CNX65_17910	COG1414	Transcriptional regulator
CNX65_17920	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CNX65_17975	COG2814	Major facilitator Superfamily
CNX65_18005	COG0438	transferase activity, transferring glycosyl groups
CNX65_18005	COG1216	Glycosyl transferase, family 2
CNX65_18040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNX65_18055	COG1404	Belongs to the peptidase S8 family
CNX65_18060	COG1309	transcriptional regulator
CNX65_18065	COG0667	Aldo Keto reductase
CNX65_18070	COG4552	Acetyltransferase involved in intracellular survival and related
CNX65_18080	COG3629	intracellular signal transduction
CNX65_18080	COG3903	Transcriptional regulator
CNX65_18095	COG2197	response regulator
CNX65_18105	COG2124	cytochrome p450
CNX65_18130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CNX65_18135	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CNX65_18165	COG0310	cobalt ion transport
CNX65_18195	COG2508	Transcriptional regulator
CNX65_18195	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CNX65_18200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CNX65_18205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CNX65_18220	COG2124	cytochrome p450
CNX65_18240	COG1132	(ABC) transporter
CNX65_18280	COG1012	belongs to the aldehyde dehydrogenase family
CNX65_18290	COG0431	NADPH-dependent FMN reductase
CNX65_18295	COG3903	Transcriptional regulator
CNX65_18295	COG3629	intracellular signal transduction
CNX65_18305	COG0287	Prephenate dehydrogenase
CNX65_18345	COG0318	PFAM AMP-dependent synthetase and ligase
CNX65_18350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CNX65_18360	COG1131	(ABC) transporter
CNX65_18370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CNX65_18375	COG0508	dehydrogenase complex catalyzes the overall conversion of
CNX65_18375	COG0022	dehydrogenase e1 component
CNX65_18385	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CNX65_18400	COG1132	(ABC) transporter
CNX65_18405	COG1132	(ABC) transporter
CNX65_18415	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CNX65_18430	COG0110	maltose O-acetyltransferase activity
CNX65_18475	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CNX65_18510	COG1132	(ABC) transporter
CNX65_18540	COG1309	transcriptional regulator
CNX65_18565	COG3290	protein histidine kinase activity
CNX65_18570	COG4565	transcriptional regulatory protein
CNX65_18580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNX65_18585	COG1309	transcriptional regulator
CNX65_18680	COG3395	kinase activity
CNX65_18685	COG0235	Class ii aldolase
CNX65_18690	COG1349	DNA-binding transcription factor activity
CNX65_18705	COG0387	Pfam Sodium calcium exchanger
CNX65_18725	COG2205	protein histidine kinase activity
CNX65_18725	COG2198	Histidine kinase
CNX65_18725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CNX65_18725	COG0784	Response regulator, receiver
CNX65_18735	COG2172	sigma factor antagonist activity
CNX65_18740	COG1366	Belongs to the anti-sigma-factor antagonist family
CNX65_18745	COG1366	Belongs to the anti-sigma-factor antagonist family
CNX65_18760	COG2072	flavoprotein involved in K transport
CNX65_18830	COG3537	Alpha-1,2-mannosidase
CNX65_18845	COG0789	Transcriptional regulator
CNX65_18870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CNX65_18980	COG3345	alpha-galactosidase
CNX65_19000	COG1733	regulation of RNA biosynthetic process
CNX65_19005	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CNX65_19010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CNX65_19030	COG1959	2 iron, 2 sulfur cluster binding
CNX65_19035	COG1017	nitric oxide dioxygenase activity
CNX65_19035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CNX65_19080	COG4106	trans-aconitate 2-methyltransferase activity
CNX65_19105	COG0667	Aldo Keto reductase
CNX65_19145	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CNX65_19215	COG3537	Alpha-1,2-mannosidase
CNX65_19220	COG0596	Alpha beta hydrolase
CNX65_19245	COG2814	Major facilitator Superfamily
CNX65_19255	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CNX65_19315	COG2755	lipolytic protein G-D-S-L family
CNX65_19325	COG0745	RESPONSE REGULATOR receiver
CNX65_19340	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CNX65_19375	COG5520	Belongs to the glycosyl hydrolase 30 family
CNX65_19390	COG0840	transmembrane signaling receptor activity
CNX65_19420	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CNX65_19440	COG0798	PFAM Bile acid sodium symporter
CNX65_19450	COG2072	flavoprotein involved in K transport
CNX65_19460	COG0456	acetyltransferase
CNX65_19485	COG2910	NAD(P)H-binding
CNX65_19520	COG0477	Major facilitator Superfamily
CNX65_19530	COG2072	flavoprotein involved in K transport
CNX65_19540	COG0657	acetylesterase activity
CNX65_19650	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
CNX65_19660	COG1120	ATPase activity
CNX65_19665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_19700	COG3940	Belongs to the glycosyl hydrolase 43 family
CNX65_19765	COG1309	transcriptional regulator
CNX65_19805	COG3866	Pectate lyase
CNX65_19810	COG3509	depolymerase
CNX65_19825	COG2367	Beta-lactamase
CNX65_19840	COG1064	alcohol dehydrogenase
CNX65_19900	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CNX65_19905	COG1309	transcriptional regulator
CNX65_19910	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_19925	COG3226	Transcriptional regulator
CNX65_19930	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CNX65_19945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CNX65_19965	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_19975	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_19980	COG0435	Glutathione S-transferase
CNX65_20005	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CNX65_20025	COG3851	Histidine kinase
CNX65_20030	COG2197	response regulator
CNX65_20070	COG0673	inositol 2-dehydrogenase activity
CNX65_20100	COG0745	RESPONSE REGULATOR receiver
CNX65_20105	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CNX65_20135	COG1472	Belongs to the glycosyl hydrolase 3 family
CNX65_20195	COG0492	ferredoxin-NADP+ reductase activity
CNX65_20210	COG0475	glutathione-regulated potassium exporter activity
CNX65_20220	COG5000	phosphorelay sensor kinase activity
CNX65_20220	COG5002	protein histidine kinase activity
CNX65_20265	COG1136	(ABC) transporter
CNX65_20265	COG0577	efflux transmembrane transporter activity
CNX65_20280	COG2197	response regulator
CNX65_20285	COG3851	Histidine kinase
CNX65_20360	COG2814	Major facilitator Superfamily
CNX65_20370	COG5002	protein histidine kinase activity
CNX65_20375	COG0745	RESPONSE REGULATOR receiver
CNX65_20385	COG1136	(ABC) transporter
CNX65_20385	COG0577	efflux transmembrane transporter activity
CNX65_20390	COG0577	efflux transmembrane transporter activity
CNX65_20420	COG2345	Transcriptional regulator
CNX65_20455	COG1960	acyl-CoA dehydrogenase activity
CNX65_20465	COG2814	Major facilitator Superfamily
CNX65_20495	COG0596	Alpha beta hydrolase
CNX65_20520	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CNX65_20530	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_20545	COG2124	cytochrome p450
CNX65_20605	COG0318	PFAM AMP-dependent synthetase and ligase
CNX65_20610	COG1024	Enoyl-CoA hydratase
CNX65_20625	COG4977	sequence-specific DNA binding
CNX65_20625	COG1917	Cupin 2, conserved barrel domain protein
CNX65_20640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CNX65_20675	COG1609	Transcriptional regulator
CNX65_20685	COG4948	Mandelate Racemase Muconate Lactonizing
CNX65_20750	COG2267	carboxylic ester hydrolase activity
CNX65_20815	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CNX65_20825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CNX65_20845	COG1414	Transcriptional regulator
CNX65_20850	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CNX65_20855	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CNX65_20895	COG3340	Belongs to the peptidase S51 family
CNX65_20935	COG0024	Methionine aminopeptidase
CNX65_20940	COG3903	Transcriptional regulator
CNX65_20940	COG3629	intracellular signal transduction
CNX65_20955	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CNX65_20965	COG4221	oxidoreductase activity
CNX65_20985	COG0840	transmembrane signaling receptor activity
CNX65_21000	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CNX65_21005	COG1404	Belongs to the peptidase S8 family
CNX65_21010	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CNX65_21010	COG3266	domain, Protein
CNX65_21010	COG4932	domain protein
CNX65_21035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CNX65_21040	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CNX65_21050	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CNX65_21060	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CNX65_21060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CNX65_21070	COG0697	spore germination
CNX65_21075	COG0644	oxidoreductase
CNX65_21115	COG0483	inositol monophosphate 1-phosphatase activity
CNX65_21150	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CNX65_21165	COG0659	secondary active sulfate transmembrane transporter activity
CNX65_21180	COG2255	four-way junction helicase activity
CNX65_21215	COG3467	pyridoxamine 5'-phosphate
CNX65_21220	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CNX65_21225	COG2124	cytochrome p450
CNX65_21230	COG0514	ATP-dependent DNA helicase (RecQ)
CNX65_21235	COG0726	polysaccharide deacetylase
CNX65_21240	COG0439	Biotin carboxylase
CNX65_21245	COG0395	ABC-type sugar transport system, permease component
CNX65_21250	COG1175	transmembrane transport
CNX65_21255	COG2182	Extracellular solute-binding protein
CNX65_21265	COG0667	Aldo Keto reductase
CNX65_21285	COG0300	oxidoreductase activity
CNX65_21325	COG0110	maltose O-acetyltransferase activity
CNX65_21330	COG1181	Belongs to the D-alanine--D-alanine ligase family
CNX65_21350	COG2197	response regulator
CNX65_21355	COG3850	Histidine kinase
CNX65_21370	COG1695	Transcriptional regulator
CNX65_21375	COG3831	ATPase activity
CNX65_21420	COG0596	Alpha beta hydrolase
CNX65_21435	COG0534	Mate efflux family protein
CNX65_21450	COG0640	Transcriptional regulator
CNX65_21465	COG0640	Transcriptional regulator
CNX65_21470	COG0672	)-iron permease
CNX65_21480	COG2837	iron assimilation
CNX65_21500	COG0596	Alpha beta hydrolase
CNX65_21505	COG1120	ATPase activity
CNX65_21510	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_21515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_21540	COG1982	Orn Lys Arg decarboxylase major
CNX65_21570	COG0277	FAD linked oxidase domain protein
CNX65_21590	COG0583	DNA-binding transcription factor activity
CNX65_21595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNX65_21600	COG1960	acyl-CoA dehydrogenase activity
CNX65_21640	COG0747	negative chemotaxis
CNX65_21650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CNX65_21655	COG4172	Belongs to the ABC transporter superfamily
CNX65_21700	COG0784	Response regulator, receiver
CNX65_21715	COG1522	sequence-specific DNA binding
CNX65_21725	COG0861	Integral membrane protein TerC family
CNX65_21730	COG1309	transcriptional regulator
CNX65_21740	COG2807	transmembrane transport
CNX65_21765	COG2814	Major facilitator Superfamily
CNX65_21785	COG0745	RESPONSE REGULATOR receiver
CNX65_21795	COG2986	histidine ammonia-lyase
CNX65_21805	COG0318	PFAM AMP-dependent synthetase and ligase
CNX65_21820	COG0604	alcohol dehydrogenase
CNX65_21820	COG3321	synthase
CNX65_21840	COG1819	glycosyl
CNX65_21860	COG1960	acyl-CoA dehydrogenase activity
CNX65_21875	COG0183	Belongs to the thiolase family
CNX65_21880	COG1024	Enoyl-CoA hydratase
CNX65_21880	COG1250	3-hydroxyacyl-CoA dehydrogenase
CNX65_21910	COG1201	RNA secondary structure unwinding
CNX65_21925	COG0556	nucleotide-excision repair
CNX65_21940	COG0142	geranyltranstransferase activity
CNX65_21945	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CNX65_21950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CNX65_21960	COG2175	clavaminate synthase activity
CNX65_21975	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CNX65_22000	COG2340	Cysteine-rich secretory protein family
CNX65_22015	COG1309	transcriptional regulator
CNX65_22030	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_22035	COG1309	transcriptional regulator
CNX65_22040	COG0789	Transcriptional regulator
CNX65_22055	COG1132	(ABC) transporter
CNX65_22060	COG1132	(ABC) transporter
CNX65_22065	COG3831	ATPase activity
CNX65_22080	COG0438	transferase activity, transferring glycosyl groups
CNX65_22110	COG0254	rRNA binding
CNX65_22120	COG0753	catalase activity
CNX65_22125	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CNX65_22125	COG0519	Catalyzes the synthesis of GMP from XMP
CNX65_22130	COG2258	MOSC domain
CNX65_22150	COG0604	alcohol dehydrogenase
CNX65_22160	COG0604	alcohol dehydrogenase
CNX65_22180	COG0583	DNA-binding transcription factor activity
CNX65_22195	COG0730	response to heat
CNX65_22210	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_22235	COG3903	Transcriptional regulator
CNX65_22235	COG3629	intracellular signal transduction
CNX65_22255	COG1022	Amp-dependent synthetase and ligase
CNX65_22270	COG1309	transcriptional regulator
CNX65_22275	COG0778	Nitroreductase
CNX65_22305	COG1063	alcohol dehydrogenase
CNX65_22330	COG1509	lysine 2,3-aminomutase activity
CNX65_22340	COG0644	oxidoreductase
CNX65_22345	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CNX65_22350	COG2808	Putative FMN-binding domain
CNX65_22400	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CNX65_22405	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CNX65_22440	COG3973	AAA domain
CNX65_22455	COG2205	protein histidine kinase activity
CNX65_22460	COG0745	RESPONSE REGULATOR receiver
CNX65_22555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CNX65_22600	COG1674	ftsk spoiiie
CNX65_22760	COG1088	dTDP-glucose 4,6-dehydratase activity
CNX65_22765	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CNX65_22770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CNX65_22775	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CNX65_22780	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CNX65_22785	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CNX65_22800	COG1132	(ABC) transporter
CNX65_22805	COG1132	(ABC) transporter
CNX65_22830	COG1404	Belongs to the peptidase S8 family
CNX65_22855	COG0561	phosphatase activity
CNX65_22890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CNX65_22895	COG3845	ABC transporter
CNX65_22900	COG1122	ATPase activity
CNX65_22915	COG1609	Transcriptional regulator
CNX65_22925	COG1175	transmembrane transport
CNX65_22980	COG1302	Protein conserved in bacteria
CNX65_23015	COG3321	synthase
CNX65_23015	COG0604	alcohol dehydrogenase
CNX65_23050	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_23055	COG1309	transcriptional regulator
CNX65_23065	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_23095	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CNX65_23110	COG0583	DNA-binding transcription factor activity
CNX65_23115	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CNX65_23120	COG3250	beta-galactosidase activity
CNX65_23130	COG4566	intracellular signal transduction
CNX65_23205	COG1022	Amp-dependent synthetase and ligase
CNX65_23220	COG0022	dehydrogenase e1 component
CNX65_23220	COG0508	dehydrogenase complex catalyzes the overall conversion of
CNX65_23225	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CNX65_23245	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_23270	COG2755	lipolytic protein G-D-S-L family
CNX65_23295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNX65_23330	COG1309	transcriptional regulator
CNX65_23335	COG0318	PFAM AMP-dependent synthetase and ligase
CNX65_23340	COG1012	belongs to the aldehyde dehydrogenase family
CNX65_23395	COG3321	synthase
CNX65_23395	COG0604	alcohol dehydrogenase
CNX65_23415	COG0702	epimerase
CNX65_23430	COG1733	regulation of RNA biosynthetic process
CNX65_23465	COG0006	proline dipeptidase activity
CNX65_23480	COG0444	Belongs to the ABC transporter superfamily
CNX65_23495	COG0747	negative chemotaxis
CNX65_23500	COG1802	Transcriptional regulator
CNX65_23510	COG3938	Belongs to the proline racemase family
CNX65_23515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CNX65_23530	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CNX65_23535	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CNX65_23540	COG1609	Transcriptional regulator
CNX65_23550	COG0402	S-adenosylhomocysteine deaminase activity
CNX65_23580	COG1131	(ABC) transporter
CNX65_23590	COG1595	DNA-templated transcription, initiation
CNX65_23600	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CNX65_23610	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CNX65_23655	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CNX65_23690	COG1121	(ABC) transporter
CNX65_23695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CNX65_23705	COG0523	cobalamin synthesis protein
CNX65_23755	COG1120	ATPase activity
CNX65_23760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_23800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CNX65_23805	COG0840	transmembrane signaling receptor activity
CNX65_23820	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_23830	COG1309	transcriptional regulator
CNX65_23835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CNX65_23840	COG2391	methyltransferase activity
CNX65_23845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CNX65_23860	COG0477	Major facilitator Superfamily
CNX65_23920	COG2018	Roadblock/LC7 domain
CNX65_23935	COG0673	inositol 2-dehydrogenase activity
CNX65_23950	COG1929	Belongs to the glycerate kinase type-1 family
CNX65_23970	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CNX65_24010	COG2124	cytochrome p450
CNX65_24020	COG1216	Glycosyl transferase, family 2
CNX65_24030	COG0702	epimerase
CNX65_24050	COG3386	PFAM SMP-30 Gluconolaconase
CNX65_24055	COG2072	flavoprotein involved in K transport
CNX65_24105	COG0456	acetyltransferase
CNX65_24125	COG1414	Transcriptional regulator
CNX65_24130	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CNX65_24140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CNX65_24150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CNX65_24165	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CNX65_24175	COG0583	DNA-binding transcription factor activity
CNX65_24190	COG1902	pentaerythritol trinitrate reductase activity
CNX65_24220	COG1802	Transcriptional regulator
CNX65_24230	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_24235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_24260	COG2208	phosphoserine phosphatase activity
CNX65_24260	COG2770	Histidine kinase
CNX65_24270	COG2365	Tyrosine phosphatase family
CNX65_24280	COG2755	lipolytic protein G-D-S-L family
CNX65_24285	COG3835	regulator
CNX65_24295	COG0601	transmembrane transport
CNX65_24320	COG1929	Belongs to the glycerate kinase type-1 family
CNX65_24330	COG2205	protein histidine kinase activity
CNX65_24335	COG0745	RESPONSE REGULATOR receiver
CNX65_24360	COG0583	DNA-binding transcription factor activity
CNX65_24395	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CNX65_24440	COG0463	Glycosyl transferase, family 2
CNX65_24450	COG0438	transferase activity, transferring glycosyl groups
CNX65_24475	COG1472	Belongs to the glycosyl hydrolase 3 family
CNX65_24490	COG2267	carboxylic ester hydrolase activity
CNX65_24495	COG3693	PFAM glycoside hydrolase, family 10
CNX65_24505	COG0500	methyltransferase
CNX65_24515	COG2409	Drug exporters of the RND superfamily
CNX65_24535	COG1253	flavin adenine dinucleotide binding
CNX65_24560	COG0009	L-threonylcarbamoyladenylate synthase
CNX65_24585	COG0586	Pfam SNARE associated Golgi protein
CNX65_24605	COG2197	response regulator
CNX65_24645	COG1012	belongs to the aldehyde dehydrogenase family
CNX65_24650	COG1063	alcohol dehydrogenase
CNX65_24665	COG2197	response regulator
CNX65_24675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CNX65_24680	COG0508	dehydrogenase complex catalyzes the overall conversion of
CNX65_24695	COG1522	sequence-specific DNA binding
CNX65_24700	COG2340	Cysteine-rich secretory protein family
CNX65_24705	COG2205	protein histidine kinase activity
CNX65_24750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CNX65_24755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CNX65_24770	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CNX65_24790	COG0463	Glycosyl transferase, family 2
CNX65_24795	COG1064	alcohol dehydrogenase
CNX65_24800	COG1309	transcriptional regulator
CNX65_24810	COG2855	membrane
CNX65_24820	COG0745	RESPONSE REGULATOR receiver
CNX65_24825	COG4251	negative regulation of phosphorylation
CNX65_24830	COG0784	Response regulator, receiver
CNX65_24865	COG3973	AAA domain
CNX65_24885	COG1309	transcriptional regulator
CNX65_24890	COG0300	oxidoreductase activity
CNX65_24900	COG0823	Involved in the tonB-independent uptake of proteins
CNX65_24905	COG3973	AAA domain
CNX65_24910	COG1120	ATPase activity
CNX65_24915	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_24920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_24940	COG4607	ABC-type enterochelin transport system periplasmic component
CNX65_24945	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CNX65_24950	COG1132	(ABC) transporter
CNX65_24955	COG1132	(ABC) transporter
CNX65_24960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CNX65_24970	COG1233	COG1233 Phytoene dehydrogenase and related
CNX65_25230	COG0583	DNA-binding transcription factor activity
CNX65_25250	COG1414	Transcriptional regulator
CNX65_25255	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CNX65_25265	COG3485	protocatechuate 3,4-dioxygenase
CNX65_25275	COG3485	protocatechuate 3,4-dioxygenase
CNX65_25280	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CNX65_25285	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CNX65_25300	COG2770	Histidine kinase
CNX65_25300	COG2208	phosphoserine phosphatase activity
CNX65_25305	COG5002	protein histidine kinase activity
CNX65_25305	COG0784	Response regulator, receiver
CNX65_25320	COG0248	Ppx GppA phosphatase
CNX65_25345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNX65_25355	COG1609	Transcriptional regulator
CNX65_25365	COG0300	oxidoreductase activity
CNX65_25370	COG1309	transcriptional regulator
CNX65_25435	COG1609	Transcriptional regulator
CNX65_25450	COG0739	heme binding
CNX65_25455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CNX65_25460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CNX65_25470	COG0596	Alpha beta hydrolase
CNX65_25485	COG0583	DNA-binding transcription factor activity
CNX65_25495	COG1349	DNA-binding transcription factor activity
CNX65_25500	COG4821	SIS domain
CNX65_25505	COG1132	(ABC) transporter
CNX65_25520	COG0488	(ABC) transporter
CNX65_25525	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_25560	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CNX65_25595	COG3706	GGDEF domain
CNX65_25600	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CNX65_25610	COG2151	metal-sulfur cluster biosynthetic enzyme
CNX65_25615	COG0822	iron-sulfur transferase activity
CNX65_25625	COG0396	ATPase activity
CNX65_25665	COG1752	Esterase of the alpha-beta hydrolase superfamily
CNX65_25670	COG0438	transferase activity, transferring glycosyl groups
CNX65_25680	COG1131	(ABC) transporter
CNX65_25715	COG1510	regulation of RNA biosynthetic process
CNX65_25725	COG2018	Roadblock/LC7 domain
CNX65_25730	COG5002	protein histidine kinase activity
CNX65_25740	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CNX65_25795	COG0109	protoheme IX farnesyltransferase activity
CNX65_25805	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CNX65_25810	COG0166	Belongs to the GPI family
CNX65_25825	COG0363	glucosamine-6-phosphate deaminase activity
CNX65_25830	COG4585	Histidine kinase
CNX65_25855	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CNX65_25860	COG0149	triose-phosphate isomerase activity
CNX65_25865	COG0126	phosphoglycerate kinase activity
CNX65_25870	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CNX65_25885	COG1481	regulation of sporulation
CNX65_25895	COG1660	Displays ATPase and GTPase activities
CNX65_25900	COG0322	excinuclease ABC activity
CNX65_25955	COG2234	aminopeptidase activity
CNX65_25965	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CNX65_25970	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CNX65_25970	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CNX65_26000	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CNX65_26005	COG0242	peptide deformylase activity
CNX65_26045	COG0405	Gamma-glutamyltransferase
CNX65_26060	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CNX65_26070	COG1758	RNA polymerase activity
CNX65_26075	COG0194	GDP metabolic process
CNX65_26085	COG0284	orotidine-5'-phosphate decarboxylase activity
CNX65_26095	COG0505	Belongs to the CarA family
CNX65_26110	COG0540	Belongs to the ATCase OTCase family
CNX65_26115	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CNX65_26125	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CNX65_26130	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CNX65_26135	COG0006	proline dipeptidase activity
CNX65_26145	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CNX65_26150	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CNX65_26155	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CNX65_26160	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CNX65_26170	COG2190	(PTS) system
CNX65_26175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CNX65_26175	COG1263	PTS System
CNX65_26185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CNX65_26185	COG1263	PTS System
CNX65_26190	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CNX65_26195	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CNX65_26205	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CNX65_26210	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CNX65_26250	COG4581	dead DEAH box helicase
CNX65_26260	COG1388	LysM domain
CNX65_26270	COG3279	Response regulator of the LytR AlgR family
CNX65_26280	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CNX65_26285	COG3275	phosphorelay sensor kinase activity
CNX65_26295	COG0237	dephospho-CoA kinase activity
CNX65_26360	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CNX65_26425	COG0395	ABC-type sugar transport system, permease component
CNX65_26470	COG2258	MOSC domain
CNX65_26475	COG0667	Aldo Keto reductase
CNX65_26495	COG2030	dehydratase
CNX65_26495	COG1012	belongs to the aldehyde dehydrogenase family
CNX65_26515	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CNX65_26515	COG2755	lipolytic protein G-D-S-L family
CNX65_26525	COG1132	(ABC) transporter
CNX65_26550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CNX65_26555	COG0564	pseudouridine synthase activity
CNX65_26605	COG1609	Transcriptional regulator
CNX65_26655	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CNX65_26655	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CNX65_26675	COG1716	ATPase activity
CNX65_26725	COG0667	Aldo Keto reductase
CNX65_26765	COG4585	Histidine kinase
CNX65_26770	COG2197	response regulator
CNX65_26775	COG2197	response regulator
CNX65_26860	COG1222	aaa ATPase
CNX65_26900	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CNX65_26905	COG1366	Belongs to the anti-sigma-factor antagonist family
CNX65_26975	COG2018	Roadblock/LC7 domain
CNX65_26985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CNX65_26995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CNX65_26995	COG1116	anion transmembrane transporter activity
CNX65_27000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CNX65_27005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CNX65_27015	COG1187	pseudouridine synthase activity
CNX65_27020	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CNX65_27025	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CNX65_27040	COG0640	Transcriptional regulator
CNX65_27065	COG0504	CTP synthase activity
CNX65_27095	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CNX65_27105	COG0647	UMP catabolic process
CNX65_27130	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CNX65_27150	COG2094	Belongs to the DNA glycosylase MPG family
CNX65_27155	COG0165	Argininosuccinate lyase
CNX65_27160	COG0137	argininosuccinate synthase activity
CNX65_27165	COG1438	arginine binding
CNX65_27180	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CNX65_27185	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CNX65_27190	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CNX65_27195	COG0604	alcohol dehydrogenase
CNX65_27200	COG1476	TRANSCRIPTIONal
CNX65_27220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CNX65_27220	COG0072	phenylalanine-tRNA ligase activity
CNX65_27225	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CNX65_27230	COG0326	Molecular chaperone. Has ATPase activity
CNX65_27240	COG0745	RESPONSE REGULATOR receiver
CNX65_27245	COG0642	Histidine kinase
CNX65_27250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CNX65_27255	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CNX65_27260	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CNX65_27265	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CNX65_27280	COG3903	Transcriptional regulator
CNX65_27280	COG3629	intracellular signal transduction
CNX65_27305	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CNX65_27310	COG2610	gluconate transmembrane transporter activity
CNX65_27330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CNX65_27350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CNX65_27355	COG0640	Transcriptional regulator
CNX65_27425	COG5650	phosphatidylinositol metabolic process
CNX65_27455	COG0823	Involved in the tonB-independent uptake of proteins
CNX65_27455	COG4946	Tricorn protease homolog
CNX65_27455	COG1506	peptidase
CNX65_27460	COG0861	Integral membrane protein TerC family
CNX65_27465	COG1131	(ABC) transporter
CNX65_27495	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CNX65_27495	COG0237	dephospho-CoA kinase activity
CNX65_27505	COG0539	negative regulation of cytoplasmic translation
CNX65_27510	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CNX65_27525	COG1511	domain protein
CNX65_27530	COG1309	transcriptional regulator
CNX65_27545	COG0673	inositol 2-dehydrogenase activity
CNX65_27565	COG0410	ABC transporter
CNX65_27610	COG1832	CoA-binding protein
CNX65_27615	COG0251	oxidation-reduction process
CNX65_27630	COG1357	PFAM Pentapeptide repeats (8 copies)
CNX65_27635	COG0514	ATP-dependent DNA helicase (RecQ)
CNX65_27670	COG1937	Protein conserved in bacteria
CNX65_27690	COG1595	DNA-templated transcription, initiation
CNX65_27695	COG1408	metallophosphoesterase
CNX65_27705	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CNX65_27720	COG0778	Nitroreductase
CNX65_27725	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CNX65_27730	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CNX65_27740	COG1566	PFAM secretion protein HlyD family protein
CNX65_27750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CNX65_27755	COG1960	acyl-CoA dehydrogenase activity
CNX65_27765	COG0183	Belongs to the thiolase family
CNX65_27770	COG1024	Enoyl-CoA hydratase
CNX65_27770	COG1250	3-hydroxyacyl-CoA dehydrogenase
CNX65_27795	COG1136	(ABC) transporter
CNX65_27795	COG0577	efflux transmembrane transporter activity
CNX65_27800	COG0577	efflux transmembrane transporter activity
CNX65_27800	COG1136	(ABC) transporter
CNX65_27805	COG1672	PFAM Archaeal ATPase
CNX65_27805	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CNX65_27810	COG3629	intracellular signal transduction
CNX65_27810	COG3903	Transcriptional regulator
CNX65_27840	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CNX65_27870	COG1946	Acyl-CoA thioesterase
CNX65_27905	COG0070	glutamate synthase
CNX65_27905	COG0069	glutamate synthase activity
CNX65_27905	COG0067	glutamate synthase
CNX65_27910	COG1301	dicarboxylic acid transport
CNX65_27925	COG2205	protein histidine kinase activity
CNX65_27935	COG0745	RESPONSE REGULATOR receiver
CNX65_27940	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CNX65_27945	COG0159	tryptophan synthase activity
CNX65_27950	COG0133	tryptophan synthase activity
CNX65_27955	COG0134	indole-3-glycerol-phosphate synthase activity
CNX65_27965	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CNX65_27975	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CNX65_27985	COG0107	imidazoleglycerol-phosphate synthase activity
CNX65_27990	COG3654	unkown
CNX65_28005	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CNX65_28010	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CNX65_28020	COG3958	Transketolase
CNX65_28025	COG3959	Transketolase, thiamine diphosphate binding domain
CNX65_28035	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CNX65_28040	COG0131	Imidazoleglycerol-phosphate dehydratase
CNX65_28045	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CNX65_28050	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CNX65_28060	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CNX65_28085	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CNX65_28130	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CNX65_28145	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CNX65_28160	COG2814	Major facilitator Superfamily
CNX65_28170	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CNX65_28180	COG3263	regulation of cellular component size
CNX65_28195	COG1872	DUF167
CNX65_28200	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CNX65_28220	COG1799	cell septum assembly
CNX65_28240	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CNX65_28245	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CNX65_28250	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CNX65_28265	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CNX65_28270	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CNX65_28285	COG0768	penicillin binding
CNX65_28295	COG0275	rRNA processing
CNX65_28300	COG2001	Belongs to the MraZ family
CNX65_28305	COG0714	Associated with various cellular activities
CNX65_28345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CNX65_28360	COG0174	glutamine synthetase
CNX65_28375	COG1192	Involved in chromosome partitioning
CNX65_28380	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CNX65_28385	COG0167	dihydroorotate dehydrogenase activity
CNX65_28395	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_28400	COG2233	PERMEase
CNX65_28415	COG1396	sequence-specific DNA binding
CNX65_28420	COG1546	Belongs to the CinA family
CNX65_28420	COG1058	Belongs to the CinA family
CNX65_28430	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CNX65_28435	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CNX65_28460	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CNX65_28465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CNX65_28485	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CNX65_28500	COG1309	transcriptional regulator
CNX65_28530	COG0667	Aldo Keto reductase
CNX65_28535	COG3214	Protein conserved in bacteria
CNX65_28555	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CNX65_28560	COG0612	Peptidase, M16
CNX65_28565	COG1185	polyribonucleotide nucleotidyltransferase activity
CNX65_28570	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CNX65_28590	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CNX65_28605	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CNX65_28610	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CNX65_28635	COG0779	Required for maturation of 30S ribosomal subunits
CNX65_28660	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_28685	COG0442	prolyl-tRNA aminoacylation
CNX65_28695	COG3022	response to hydroperoxide
CNX65_28705	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CNX65_28720	COG0513	Belongs to the DEAD box helicase family
CNX65_28725	COG1648	precorrin-2 dehydrogenase activity
CNX65_28725	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CNX65_28775	COG0156	8-amino-7-oxononanoate synthase activity
CNX65_28790	COG1280	lysine exporter protein (LysE YggA)
CNX65_28805	COG0501	Belongs to the peptidase M48B family
CNX65_28815	COG0110	maltose O-acetyltransferase activity
CNX65_28820	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CNX65_28830	COG1752	Esterase of the alpha-beta hydrolase superfamily
CNX65_28835	COG0726	polysaccharide deacetylase
CNX65_28840	COG1881	PFAM PEBP family protein
CNX65_28850	COG2807	transmembrane transport
CNX65_28855	COG2186	Transcriptional regulator
CNX65_28870	COG1492	cobalamin metabolic process
CNX65_28895	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CNX65_28905	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CNX65_28920	COG2197	response regulator
CNX65_28925	COG4585	Histidine kinase
CNX65_28930	COG1177	transmembrane transport
CNX65_28935	COG1176	ABC-type spermidine putrescine transport system, permease component I
CNX65_28945	COG3842	ATPase activity
CNX65_28955	COG0515	serine threonine protein kinase
CNX65_28965	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CNX65_28975	COG0667	Aldo Keto reductase
CNX65_28995	COG0233	cytoplasmic translational termination
CNX65_29000	COG0528	UMP kinase activity
CNX65_29005	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CNX65_29010	COG0052	Belongs to the universal ribosomal protein uS2 family
CNX65_29020	COG1191	sigma factor activity
CNX65_29035	COG0606	chelatase, subunit chli
CNX65_29040	COG0792	nuclease activity
CNX65_29050	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CNX65_29055	COG0681	Belongs to the peptidase S26 family
CNX65_29060	COG0681	Belongs to the peptidase S26 family
CNX65_29065	COG0335	large ribosomal subunit rRNA binding
CNX65_29070	COG0336	Belongs to the RNA methyltransferase TrmD family
CNX65_29085	COG0228	four-way junction DNA binding
CNX65_29090	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CNX65_29125	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CNX65_29145	COG4266	Belongs to the allantoicase family
CNX65_29150	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CNX65_29180	COG1414	Transcriptional regulator
CNX65_29195	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CNX65_29210	COG0454	-acetyltransferase
CNX65_29210	COG0456	acetyltransferase
CNX65_29245	COG1254	Belongs to the acylphosphatase family
CNX65_29250	COG2340	Cysteine-rich secretory protein family
CNX65_29265	COG1252	NADH dehydrogenase
CNX65_29280	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CNX65_29290	COG0571	ribonuclease III activity
CNX65_29295	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CNX65_29310	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CNX65_29315	COG0742	ribosomal rna small subunit methyltransferase
CNX65_29350	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CNX65_29370	COG1461	Dihydroxyacetone kinase
CNX65_29375	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CNX65_29395	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CNX65_29400	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CNX65_29425	COG1181	Belongs to the D-alanine--D-alanine ligase family
CNX65_29440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CNX65_29455	COG3344	reverse transcriptase
CNX65_29490	COG0626	cystathionine gamma-synthase activity
CNX65_29495	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CNX65_29530	COG0066	3-isopropylmalate dehydratase activity
CNX65_29535	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CNX65_29565	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CNX65_29575	COG0179	Fumarylacetoacetate (FAA) hydrolase
CNX65_29585	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CNX65_29590	COG0473	3-isopropylmalate dehydrogenase activity
CNX65_29595	COG1404	Belongs to the peptidase S8 family
CNX65_29610	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CNX65_29615	COG0440	acetolactate synthase activity
CNX65_29635	COG0129	dihydroxy-acid dehydratase activity
CNX65_29640	COG2259	Doxx family
CNX65_29685	COG0154	amidase activity
CNX65_29690	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CNX65_29705	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CNX65_29720	COG2855	membrane
CNX65_29755	COG0482	sulfurtransferase activity
CNX65_29780	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CNX65_29790	COG1307	EDD domain protein, DegV family
CNX65_29805	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CNX65_29835	COG0110	maltose O-acetyltransferase activity
CNX65_29860	COG1119	ATPase activity
CNX65_29885	COG0058	SHG alpha-glucan phosphorylase activity
CNX65_29890	COG0366	Alpha amylase catalytic
CNX65_29895	COG0366	Alpha amylase catalytic
CNX65_29910	COG2321	neutral zinc metallopeptidase
CNX65_29935	COG1846	Transcriptional regulator
CNX65_29945	COG2409	Drug exporters of the RND superfamily
CNX65_29950	COG1131	(ABC) transporter
CNX65_29965	COG1609	Transcriptional regulator
CNX65_29980	COG1172	Belongs to the binding-protein-dependent transport system permease family
CNX65_29985	COG1879	ABC-type sugar transport system periplasmic component
CNX65_29995	COG0596	Alpha beta hydrolase
CNX65_30035	COG0183	Belongs to the thiolase family
CNX65_30075	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CNX65_30085	COG2376	Dihydroxyacetone kinase
CNX65_30140	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CNX65_30155	COG1024	Enoyl-CoA hydratase
CNX65_30195	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CNX65_30200	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CNX65_30205	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CNX65_30210	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CNX65_30215	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CNX65_30220	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CNX65_30225	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CNX65_30230	COG0356	it plays a direct role in the translocation of protons across the membrane
CNX65_30245	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CNX65_30260	COG2890	protein-(glutamine-N5) methyltransferase activity
CNX65_30275	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CNX65_30280	COG0254	rRNA binding
CNX65_30290	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CNX65_30295	COG0083	homoserine kinase activity
CNX65_30300	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CNX65_30305	COG0460	homoserine dehydrogenase
CNX65_30310	COG0019	diaminopimelate decarboxylase activity
CNX65_30315	COG0018	arginyl-trna synthetase
CNX65_30330	COG3537	Alpha-1,2-mannosidase
CNX65_30365	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CNX65_30370	COG3903	Transcriptional regulator
CNX65_30370	COG3629	intracellular signal transduction
CNX65_30375	COG0596	Alpha beta hydrolase
CNX65_30415	COG1162	GTPase activity
CNX65_30425	COG0667	Aldo Keto reductase
CNX65_30430	COG1609	Transcriptional regulator
CNX65_30460	COG0444	Belongs to the ABC transporter superfamily
CNX65_30465	COG0601	transmembrane transport
CNX65_30470	COG4166	transmembrane transport
CNX65_30495	COG2890	protein-(glutamine-N5) methyltransferase activity
CNX65_30500	COG4941	Belongs to the sigma-70 factor family
CNX65_30505	COG3795	YCII-related domain
CNX65_30535	COG0640	Transcriptional regulator
CNX65_30545	COG1940	carbohydrate kinase activity
CNX65_30560	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CNX65_30565	COG0745	RESPONSE REGULATOR receiver
CNX65_30570	COG2205	protein histidine kinase activity
CNX65_30590	COG1404	Belongs to the peptidase S8 family
CNX65_30600	COG0583	DNA-binding transcription factor activity
CNX65_30630	COG3629	intracellular signal transduction
CNX65_30630	COG3903	Transcriptional regulator
CNX65_30645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CNX65_30650	COG1960	acyl-CoA dehydrogenase activity
CNX65_30655	COG1024	Enoyl-CoA hydratase
CNX65_30660	COG1960	acyl-CoA dehydrogenase activity
CNX65_30670	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CNX65_30710	COG3469	chitinase activity
CNX65_30715	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CNX65_30725	COG0673	inositol 2-dehydrogenase activity
CNX65_30745	COG0386	Belongs to the glutathione peroxidase family
CNX65_30750	COG1760	l-serine dehydratase
CNX65_30755	COG0509	glycine decarboxylation via glycine cleavage system
CNX65_30760	COG0686	Belongs to the AlaDH PNT family
CNX65_30785	COG1132	(ABC) transporter
CNX65_30790	COG0567	Dehydrogenase, E1 component
CNX65_30790	COG0508	dehydrogenase complex catalyzes the overall conversion of
CNX65_30805	COG0667	Aldo Keto reductase
CNX65_30820	COG3629	intracellular signal transduction
CNX65_30820	COG3903	Transcriptional regulator
CNX65_30835	COG1228	amidohydrolase
CNX65_30850	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CNX65_30855	COG2986	histidine ammonia-lyase
CNX65_30875	COG1174	glycine betaine transport
CNX65_30920	COG5001	Diguanylate cyclase
CNX65_30930	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CNX65_30950	COG0406	alpha-ribazole phosphatase activity
CNX65_30975	COG1597	lipid kinase activity
CNX65_30995	COG5662	AntiSigma factor
CNX65_31000	COG1595	DNA-templated transcription, initiation
CNX65_31005	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CNX65_31015	COG2135	peptidase activity
CNX65_31020	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CNX65_31025	COG1162	GTPase activity
CNX65_31050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CNX65_31055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CNX65_31065	COG0653	protein targeting
CNX65_31070	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CNX65_31075	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CNX65_31080	COG5401	PFAM Sporulation and spore germination
CNX65_31085	COG5002	protein histidine kinase activity
CNX65_31090	COG0745	RESPONSE REGULATOR receiver
CNX65_31105	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CNX65_31110	COG0531	amino acid
CNX65_31120	COG1482	cell wall glycoprotein biosynthetic process
CNX65_31160	COG1994	Peptidase M50
CNX65_31170	COG0778	Nitroreductase
CNX65_31170	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CNX65_31185	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CNX65_31205	COG0438	transferase activity, transferring glycosyl groups
CNX65_31225	COG0438	transferase activity, transferring glycosyl groups
CNX65_31240	COG1316	TRANSCRIPTIONal
CNX65_31245	COG1316	TRANSCRIPTIONal
CNX65_31255	COG2259	Doxx family
CNX65_31285	COG3842	ATPase activity
CNX65_31290	COG2186	Transcriptional regulator
CNX65_31335	COG0483	inositol monophosphate 1-phosphatase activity
CNX65_31340	COG0745	RESPONSE REGULATOR receiver
CNX65_31345	COG2205	protein histidine kinase activity
CNX65_31385	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CNX65_31400	COG0424	maF-like protein
CNX65_31405	COG1301	dicarboxylic acid transport
CNX65_31415	COG4770	biotin carboxylase activity
CNX65_31460	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CNX65_31465	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CNX65_31470	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CNX65_31480	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CNX65_31480	COG1473	amidohydrolase
CNX65_31510	COG0515	serine threonine protein kinase
CNX65_31520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CNX65_31540	COG3654	unkown
CNX65_31605	COG0791	NLP P60 protein
CNX65_31605	COG3883	PFAM NLP P60 protein
CNX65_31625	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CNX65_31710	COG2009	succinate dehydrogenase
CNX65_31725	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CNX65_31730	COG1686	Belongs to the peptidase S11 family
CNX65_31745	COG1295	ribonuclease BN
CNX65_31750	COG0180	Tryptophanyl-tRNA synthetase
CNX65_31760	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CNX65_31775	COG0708	Exodeoxyribonuclease III
CNX65_31810	COG0484	heat shock protein binding
CNX65_31835	COG4555	ABC transporter
CNX65_31860	COG0039	L-malate dehydrogenase activity
CNX65_31890	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CNX65_31940	COG0045	succinate-CoA ligase (ADP-forming) activity
CNX65_31995	COG0515	serine threonine protein kinase
CNX65_31995	COG2815	serine threonine protein kinase
CNX65_32000	COG0515	serine threonine protein kinase
CNX65_32005	COG0583	DNA-binding transcription factor activity
CNX65_32010	COG0697	spore germination
CNX65_32040	COG0519	Catalyzes the synthesis of GMP from XMP
CNX65_32040	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CNX65_32050	COG1012	belongs to the aldehyde dehydrogenase family
CNX65_32065	COG0516	GMP reductase activity
CNX65_32110	COG0459	protein refolding
CNX65_32115	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CNX65_32125	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CNX65_32130	COG0456	acetyltransferase
CNX65_32145	COG3118	belongs to the thioredoxin family
CNX65_32150	COG0318	PFAM AMP-dependent synthetase and ligase
CNX65_32155	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CNX65_32155	COG0825	malonyl-CoA metabolic process
CNX65_32180	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CNX65_32190	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CNX65_32215	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CNX65_32220	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CNX65_32225	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CNX65_32240	COG0443	Heat shock 70 kDa protein
CNX65_32250	COG1674	ftsk spoiiie
CNX65_32260	COG1404	Belongs to the peptidase S8 family
CNX65_32295	COG0101	tRNA pseudouridine synthase activity
CNX65_32300	COG0203	ribosomal protein L17
CNX65_32305	COG0202	RNA polymerase activity
CNX65_32310	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CNX65_32315	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CNX65_32320	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CNX65_32325	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CNX65_32350	COG0563	adenylate kinase activity
CNX65_32370	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CNX65_32375	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CNX65_32380	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CNX65_32385	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CNX65_32390	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CNX65_32395	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CNX65_32400	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CNX65_32405	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CNX65_32410	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CNX65_32415	COG0255	Belongs to the universal ribosomal protein uL29 family
CNX65_32420	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CNX65_32425	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CNX65_32430	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CNX65_32435	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CNX65_32440	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CNX65_32445	COG0089	rRNA binding
CNX65_32450	COG0088	Forms part of the polypeptide exit tunnel
CNX65_32455	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CNX65_32460	COG0051	transcription antitermination factor activity, RNA binding
CNX65_32465	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CNX65_32470	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CNX65_32475	COG0049	tRNA binding
CNX65_32480	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CNX65_32520	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CNX65_32525	COG0085	RNA polymerase activity
CNX65_32550	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CNX65_32565	COG0222	ribosome binding
CNX65_32570	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CNX65_32580	COG0081	regulation of translation
CNX65_32585	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CNX65_32595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CNX65_32605	COG0436	Aminotransferase
CNX65_32620	COG2030	dehydratase
CNX65_32625	COG2030	dehydratase
CNX65_32630	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CNX65_32795	COG1666	GTP binding
CNX65_32800	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CNX65_32810	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CNX65_32815	COG0649	NAD binding
CNX65_32815	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CNX65_32820	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CNX65_32830	COG1834	amidinotransferase
CNX65_32835	COG1522	sequence-specific DNA binding
CNX65_32845	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CNX65_32845	COG0674	pyruvate-flavodoxin oxidoreductase activity
CNX65_32850	COG1013	pyruvate-flavodoxin oxidoreductase activity
CNX65_32870	COG1007	ATP synthesis coupled electron transport
CNX65_32885	COG0713	ATP synthesis coupled electron transport
CNX65_32890	COG0839	Belongs to the complex I subunit 6 family
CNX65_32895	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CNX65_32900	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CNX65_32905	COG1034	ATP synthesis coupled electron transport
CNX65_32910	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CNX65_32920	COG0649	NAD binding
CNX65_32925	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CNX65_32930	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CNX65_32945	COG2226	methyltransferase
CNX65_32950	COG0483	inositol monophosphate 1-phosphatase activity
CNX65_32960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CNX65_32965	COG2151	metal-sulfur cluster biosynthetic enzyme
CNX65_32970	COG3396	Phenylacetate-CoA oxygenase
CNX65_32975	COG3460	Phenylacetate-CoA oxygenase
CNX65_32980	COG3396	Phenylacetate-CoA oxygenase
CNX65_33030	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CNX65_33080	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CNX65_33085	COG1333	cytochrome c biogenesis protein
CNX65_33090	COG0785	Cytochrome C biogenesis protein
CNX65_33110	COG0406	alpha-ribazole phosphatase activity
CNX65_33115	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CNX65_33155	COG0113	porphobilinogen synthase activity
CNX65_33165	COG0181	hydroxymethylbilane synthase activity
CNX65_33170	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CNX65_33175	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CNX65_33195	COG0318	PFAM AMP-dependent synthetase and ligase
CNX65_33210	COG0560	Phosphoserine phosphatase
CNX65_33240	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CNX65_33275	COG5002	protein histidine kinase activity
CNX65_33280	COG0667	Aldo Keto reductase
CNX65_33290	COG0588	phosphoglycerate mutase activity
CNX65_33295	COG0318	PFAM AMP-dependent synthetase and ligase
CNX65_33310	COG0438	transferase activity, transferring glycosyl groups
CNX65_33330	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CNX65_33360	COG3226	Transcriptional regulator
CNX65_33370	COG0789	Transcriptional regulator
CNX65_33375	COG0693	protein deglycase activity
CNX65_33405	COG2733	membrane
CNX65_33435	COG1136	(ABC) transporter
CNX65_33470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CNX65_33475	COG2364	Membrane
CNX65_33535	COG1278	Cold shock
CNX65_33540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CNX65_33555	COG2255	four-way junction helicase activity
CNX65_33695	COG0745	RESPONSE REGULATOR receiver
CNX65_33695	COG3706	GGDEF domain
CNX65_33700	COG1316	TRANSCRIPTIONal
CNX65_33720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CNX65_33740	COG0456	acetyltransferase
CNX65_33745	COG0745	RESPONSE REGULATOR receiver
CNX65_33770	COG2897	thiosulfate sulfurtransferase activity
CNX65_33780	COG4044	May play a role in the intracellular transport of hydrophobic ligands
CNX65_33785	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CNX65_33800	COG0735	belongs to the Fur family
CNX65_33820	COG2271	Major facilitator Superfamily
CNX65_33845	COG3962	Belongs to the TPP enzyme family
CNX65_33850	COG3718	enzyme involved in inositol metabolism
CNX65_33865	COG1172	Belongs to the binding-protein-dependent transport system permease family
CNX65_33875	COG1082	Xylose isomerase domain protein TIM barrel
CNX65_33885	COG1609	Transcriptional regulator
CNX65_33890	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CNX65_33905	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CNX65_33965	COG5001	Diguanylate cyclase
CNX65_33965	COG3300	MHYT domain
CNX65_33990	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CNX65_33995	COG0047	phosphoribosylformylglycinamidine synthase activity
CNX65_34000	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CNX65_34025	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CNX65_34035	COG0765	amino acid transport
CNX65_34050	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CNX65_34060	COG1595	DNA-templated transcription, initiation
CNX65_34075	COG1595	DNA-templated transcription, initiation
CNX65_34085	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CNX65_34130	COG0584	glycerophosphoryl diester phosphodiesterase
CNX65_34140	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CNX65_34170	COG4129	membrane
CNX65_34190	COG0667	Aldo Keto reductase
CNX65_34195	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_34205	COG1595	DNA-templated transcription, initiation
CNX65_34230	COG0277	FAD linked oxidase domain protein
CNX65_34235	COG0586	Pfam SNARE associated Golgi protein
CNX65_34240	COG1072	(Pantothenic acid kinase))
CNX65_34245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CNX65_34275	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CNX65_34300	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_34310	COG0542	response to heat
CNX65_34320	COG2871	sodium ion transport
CNX65_34325	COG0789	Transcriptional regulator
CNX65_34330	COG0484	heat shock protein binding
CNX65_34335	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CNX65_34340	COG0443	Heat shock 70 kDa protein
CNX65_34360	COG2181	nitrate reductase activity
CNX65_34360	COG0247	lactate metabolic process
CNX65_34365	COG1950	PFAM Membrane protein of
CNX65_34390	COG0717	Belongs to the dCTP deaminase family
CNX65_34410	COG2197	response regulator
CNX65_34415	COG1960	acyl-CoA dehydrogenase activity
CNX65_34430	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CNX65_34440	COG3311	Transcriptional regulator
CNX65_34445	COG1569	PIN domain
CNX65_34470	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_34480	COG1960	acyl-CoA dehydrogenase activity
CNX65_34490	COG1309	transcriptional regulator
CNX65_34495	COG0789	Transcriptional regulator
CNX65_34500	COG0508	dehydrogenase complex catalyzes the overall conversion of
CNX65_34505	COG0022	dehydrogenase e1 component
CNX65_34515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CNX65_34525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CNX65_34530	COG0765	amino acid transport
CNX65_34565	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CNX65_34595	COG1940	carbohydrate kinase activity
CNX65_34635	COG4585	Histidine kinase
CNX65_34640	COG2197	response regulator
CNX65_34645	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_34655	COG0561	phosphatase activity
CNX65_34670	COG4585	Histidine kinase
CNX65_34675	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CNX65_34695	COG1131	(ABC) transporter
CNX65_34710	COG0402	S-adenosylhomocysteine deaminase activity
CNX65_34715	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_34730	COG2814	Major facilitator Superfamily
CNX65_34735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CNX65_34740	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_34760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CNX65_34785	COG0360	Binds together with S18 to 16S ribosomal RNA
CNX65_34790	COG0629	single-stranded DNA binding
CNX65_34795	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CNX65_34800	COG0359	binds to the 23S rRNA
CNX65_34805	COG0305	Participates in initiation and elongation during chromosome replication
CNX65_34835	COG2203	Gaf domain
CNX65_34835	COG4251	negative regulation of phosphorylation
CNX65_34835	COG3706	GGDEF domain
CNX65_34835	COG5001	Diguanylate cyclase
CNX65_34860	COG3706	GGDEF domain
CNX65_34860	COG0745	RESPONSE REGULATOR receiver
CNX65_34895	COG0702	epimerase
CNX65_34900	COG1063	alcohol dehydrogenase
CNX65_34910	COG0583	DNA-binding transcription factor activity
CNX65_34920	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CNX65_34925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CNX65_34945	COG0495	leucyl-tRNA aminoacylation
CNX65_34965	COG2197	response regulator
CNX65_34970	COG0617	tRNA 3'-terminal CCA addition
CNX65_34990	COG0515	serine threonine protein kinase
CNX65_34995	COG1595	DNA-templated transcription, initiation
CNX65_35010	COG0492	ferredoxin-NADP+ reductase activity
CNX65_35010	COG3118	belongs to the thioredoxin family
CNX65_35015	COG3409	Peptidoglycan-binding domain 1 protein
CNX65_35015	COG0860	N-Acetylmuramoyl-L-alanine amidase
CNX65_35035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CNX65_35040	COG1181	Belongs to the D-alanine--D-alanine ligase family
CNX65_35050	COG1192	Involved in chromosome partitioning
CNX65_35055	COG0357	Ribosomal RNA small subunit methyltransferase G
CNX65_35070	COG0706	membrane insertase activity
CNX65_35075	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CNX65_35080	COG0594	ribonuclease P activity
CNX65_35085	COG0230	Belongs to the bacterial ribosomal protein bL34 family