locus-tag	class	description
APASM_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
APASM_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
APASM_0003	ENOG4108J5G	6-phosphogluconate dehydrogenase
APASM_0004	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
APASM_0005	ENOG4105K7N	UPF0232 protein
APASM_0007	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
APASM_0010	ENOG4105MGM	doxx family
APASM_0013	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
APASM_0017	ENOG4108U4N	(sortase) family
APASM_0021	ENOG4105D9P	serine threonine protein kinase
APASM_0022	ENOG4107TPY	serine threonine protein kinase
APASM_0023	ENOG4105CJN	penicillin-binding protein
APASM_0027	ENOG4105HZM	Fha domain containing protein
APASM_0028	ENOG4105TV9	FHA Domain-Containing protein
APASM_0034	ENOG4108SGK	Tetr family transcriptional regulator
APASM_0037	ENOG4108IXY	short-chain dehydrogenase reductase
APASM_0039	ENOG41070F3	Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity)
APASM_0045	ENOG4105C94	Transporter
APASM_0057	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
APASM_0060	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
APASM_0066	ENOG4108HRK	Histidine kinase
APASM_0069	ENOG4105DY9	regulatoR
APASM_0073	ENOG4107QN1	sodium solute
APASM_0075	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
APASM_0077	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
APASM_0080	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
APASM_0083	ENOG4107YEV	ferritin
APASM_0084	ENOG4105CEU	Arginine dihydrolase
APASM_0093	ENOG4105C4M	(Ubiquinol oxidase) subunit I
APASM_0094	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
APASM_0096	ENOG4108JJ9	ABC, transporter
APASM_0098	ENOG4108YM7	Gcn5-related n-acetyltransferase
APASM_0116	ENOG4106032	Glutathionylspermidine synthase
APASM_0117	ENOG4105P3N	Membrane
APASM_0119	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
APASM_0122	ENOG4105D5U	fad dependent oxidoreductase
APASM_0124	ENOG410667J	hydrolase
APASM_0126	ENOG4105CKK	Glycosyl transferase, family 2
APASM_0130	ENOG4108MKI	Glycosyl transferase, family 2
APASM_0136	ENOG4108MKI	Glycosyl transferase, family 2
APASM_0139	ENOG4108VC7	Protein of unknown function (DUF2587)
APASM_0145	ENOG4105IIU	Aminopeptidase
APASM_0150	ENOG4105CIH	Imidazole acetol-phosphate transaminase
APASM_0155	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
APASM_0159	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
APASM_0163	ENOG4105NI8	Cytosine-specific methyltransferase
APASM_0167	ENOG4105CHU	acetyl-coa acetyltransferase
APASM_0170	ENOG4105EVN	Prephenate dehydrogenase
APASM_0171	ENOG4105CH2	amidohydrolase
APASM_0173	ENOG4108Z6B	deaminase
APASM_0177	ENOG4107SDU	Methyl-accepting chemotaxis
APASM_0181	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
APASM_0182	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
APASM_0185	ENOG4105DEF	Extracellular solute-binding protein, family 5
APASM_0186	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
APASM_0187	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
APASM_0188	ENOG4105C3U	ABC transporter
APASM_0189	ENOG4108JQ7	(ABC) transporter
APASM_0196	ENOG4105CFH	Aspartokinase
APASM_0198	ENOG4105CMG	Carbohydrate kinase
APASM_0199	ENOG4105VEQ	Cold shock protein
APASM_0200	ENOG4105CH6	catalase
APASM_0201	ENOG4108ZHJ	Organic hydroperoxide resistance protein
APASM_0203	ENOG4107YFT	Nadph-dependent fmn reductase
APASM_0205	ENOG4107QVI	Methyltransferase, type 11
APASM_0209	ENOG4105DIN	metallophosphoesterase
APASM_0211	ENOG4105BZ4	penicillin-binding protein
APASM_0226	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
APASM_0227	ENOG4105C54	Major Facilitator superfamily
APASM_0234	ENOG4105D74	hydrolase
APASM_0236	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
APASM_0237	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
APASM_0240	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
APASM_0243	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
APASM_0244	ENOG4106KNT	transcriptional regulator
APASM_0248	ENOG4105EHZ	conserved protein UCP016719
APASM_0251	ENOG4105D17	glycoside hydrolase, family 3 domain protein
APASM_0262	ENOG4108I5C	dEAD DEAH box helicase
APASM_0263	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
APASM_0270	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
APASM_0273	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
APASM_0274	ENOG4105C6E	dna polymerase iii
APASM_0276	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
APASM_0277	ENOG4108HUF	Transporter
APASM_0278	ENOG4105E0A	ABC, transporter
APASM_0287	ENOG4105F0N	pyrophosphate phospho-hydrolase
APASM_0290	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
APASM_0291	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
APASM_0293	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
APASM_0294	ENOG4105EUJ	GTP cyclohydrolase i
APASM_0295	ENOG4105EEI	dihydropteroate synthase
APASM_0299	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
APASM_0304	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
APASM_0305	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
APASM_0306	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
APASM_0308	ENOG4105CRK	lysyL-tRNA synthetase
APASM_0310	ENOG4105DQ5	transport system permease protein
APASM_0311	ENOG4105TVJ	transport system, permease
APASM_0312	ENOG4105E0A	ABC, transporter
APASM_0315	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
APASM_0316	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
APASM_0318	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
APASM_0322	ENOG4105CEN	a g-specific adenine glycosylase
APASM_0325	ENOG4107T3P	ABC, transporter
APASM_0326	ENOG4105D56	permease protein
APASM_0327	ENOG4105EG2	ABC transporter, permease
APASM_0330	ENOG4105DIK	(ABC) transporter
APASM_0331	ENOG4105CC5	ABC transporter
APASM_0332	ENOG4105BZU	Histidine kinase
APASM_0335	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
APASM_0337	ENOG4105C8N	cysteinyl-tRNA synthetase
APASM_0339	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
APASM_0340	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
APASM_0341	ENOG4108VJ1	Transcriptional regulator (CarD family
APASM_0345	ENOG4105EMU	Dehydrogenase
APASM_0348	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
APASM_0351	ENOG4108NVR	Methyl-accepting chemotaxis
APASM_0352	ENOG4108W2P	Methyl-accepting chemotaxis
APASM_0354	ENOG4105BZU	Histidine kinase
APASM_0355	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
APASM_0360	ENOG41065RQ	ADP-ribosylation crystallin J1
APASM_0366	ENOG4106NZI	LysR family Transcriptional regulator
APASM_0368	ENOG4105ERH	Fumarylacetoacetate hydrolase
APASM_0369	ENOG4105DIA	mandelate racemase muconate lactonizing
APASM_0370	ENOG4105CHR	reductase
APASM_0374	ENOG4105JXH	GntR family transcriptional regulator
APASM_0376	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
APASM_0378	ENOG4105FDP	GntR family transcriptional regulator
APASM_0380	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
APASM_0381	ENOG4107Y5I	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
APASM_0382	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
APASM_0384	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
APASM_0391	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
APASM_0397	ENOG4105DWF	phosphomethylpyrimidine kinase
APASM_0398	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
APASM_0400	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
APASM_0403	ENOG4105DRR	Transcriptional regulator, GntR family
APASM_0409	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
APASM_0413	ENOG4105VEQ	Cold shock protein
APASM_0415	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
APASM_0418	ENOG4106N3A	copper homeostasis protein cutc
APASM_0420	ENOG4105HS6	binding-protein-dependent transport systems inner membrane Component
APASM_0422	ENOG4105E2D	ec 3.2.1.52
APASM_0425	ENOG4107TCW	O-succinylbenzoate synthase
APASM_0432	ENOG4105GWZ	Roadblock lc7 family protein
APASM_0440	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
APASM_0444	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
APASM_0449	ENOG410901E	Membrane
APASM_0452	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
APASM_0454	ENOG4105VEQ	Cold shock protein
APASM_0460	ENOG4105C7N	Xanthine uracil vitamin C permease
APASM_0462	ENOG4107SFI	Major Facilitator superfamily
APASM_0468	ENOG4105FCS	tRNA rRNA methyltransferase
APASM_0472	ENOG4106AM8	polysaccharide lyase family 8
APASM_0473	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
APASM_0474	ENOG4105MT3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
APASM_0476	ENOG4107S16	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
APASM_0478	ENOG4105CQM	Urea amidohydrolase subunit alpha
APASM_0483	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_0484	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
APASM_0489	ENOG4105BZ1	(ABC) transporter
APASM_0491	ENOG4105BZ1	(ABC) transporter
APASM_0493	ENOG4108JGH	Tetr family transcriptional regulator
APASM_0494	ENOG4107QHQ	amino acid
APASM_0495	ENOG4107WI4	Aldose-1-epimerase
APASM_0496	ENOG4105CI2	imidazolone-5-propionate hydrolase
APASM_0497	ENOG4105C1G	acyl-Coa dehydrogenase
APASM_0499	ENOG4105D7K	pfkb domain protein
APASM_0503	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_0505	ENOG4105RHA	ABC transporter, permease
APASM_0506	ENOG4108IUX	(ABC) transporter
APASM_0511	ENOG4105DZC	cytosine deaminase
APASM_0512	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
APASM_0515	ENOG4105EC2	ftsk spoIIIe
APASM_0520	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
APASM_0521	ENOG4107V2S	Transcriptional regulator
APASM_0522	ENOG4105JAB	phenazine biosynthesis protein, phzf family
APASM_0523	ENOG4108KXM	LysR family Transcriptional regulator
APASM_0524	ENOG4105ECR	NmrA family
APASM_0525	ENOG4105KVH	Transcriptional regulator
APASM_0531	ENOG4108S01	response regulator
APASM_0542	ENOG4105DUY	Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein
APASM_0543	ENOG4105CNA	YD repeat protein
APASM_0559	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_0560	ENOG4105BZU	Histidine kinase
APASM_0561	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
APASM_0562	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
APASM_0563	ENOG41080FR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
APASM_0564	ENOG4105W0E	50S ribosomal protein L33
APASM_0565	ENOG4105KDC	50s ribosomal protein l28
APASM_0572	ENOG4105I1K	ABC transporter
APASM_0573	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
APASM_0576	ENOG4105E98	transcriptional regulator DeoR family
APASM_0580	ENOG4105C0H	protease
APASM_0583	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
APASM_0585	ENOG41080FJ	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
APASM_0588	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
APASM_0589	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
APASM_0591	ENOG4105D9U	N-acetyltransferase
APASM_0595	ENOG4105C4R	Atp-dependent dna helicase
APASM_0596	ENOG4105D9P	serine threonine protein kinase
APASM_0601	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
APASM_0602	ENOG4105F8V	Hydrolase, tatD family
APASM_0603	ENOG4106839	domain protein
APASM_0604	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
APASM_0605	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
APASM_0606	ENOG4108UMI	ABC transporter, permease
APASM_0607	ENOG4105D01	(LipO)protein
APASM_0608	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
APASM_0609	ENOG4105C5H	ABC transporter
APASM_0612	ENOG4107RCI	amp-dependent synthetase and ligase
APASM_0613	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
APASM_0615	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
APASM_0617	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
APASM_0618	ENOG4105BZU	Histidine kinase
APASM_0628	ENOG4105DXN	mazG family
APASM_0629	ENOG4107RE3	peptidase, S41
APASM_0632	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
APASM_0636	ENOG4108J59	Extracellular solute-binding protein, family 5
APASM_0637	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
APASM_0638	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
APASM_0639	ENOG4105C3U	ABC transporter
APASM_0640	ENOG4108JQ7	(ABC) transporter
APASM_0643	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
APASM_0656	ENOG4105CHU	acetyl-coa acetyltransferase
APASM_0662	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
APASM_0664	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
APASM_0666	ENOG4105T1M	mycothiol conjugate amidase mca
APASM_0670	ENOG4105C7Z	Conserved Protein
APASM_0675	ENOG4108IAB	Phoh family
APASM_0677	ENOG4107RYT	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
APASM_0678	ENOG4105C9Q	fumarate hydratase class II
APASM_0679	ENOG4105CAY	ferredoxin--nadp reductase
APASM_0683	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
APASM_0685	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
APASM_0687	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
APASM_0691	ENOG4105EYH	Exonuclease
APASM_0694	ENOG4105C3G	gtp-binding protein
APASM_0699	ENOG4108U8T	Mannosyltransferase
APASM_0701	ENOG410842T	Pterin carbinolamine dehydratase
APASM_0703	ENOG4105E0C	molybdate abc transporter
APASM_0704	ENOG4108UCS	ABC, transporter
APASM_0709	ENOG4105CJ1	ABC, transporter
APASM_0715	ENOG4105C31	Tryptophanyl-tRNA synthetase
APASM_0718	ENOG4105CI3	gtp-binding protein typa
APASM_0719	ENOG4107USK	Extracellular solute-binding protein, family 5
APASM_0720	ENOG4108J59	Extracellular solute-binding protein, family 5
APASM_0724	ENOG4108JQ7	(ABC) transporter
APASM_0725	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
APASM_0729	ENOG4108Z4U	Ferredoxin
APASM_0732	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
APASM_0733	ENOG4108URH	decarboxylase
APASM_0734	ENOG4108URH	decarboxylase
APASM_0736	ENOG4105EEI	dihydropteroate synthase
APASM_0740	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
APASM_0745	ENOG4108UKI	Enoyl-CoA hydratase
APASM_0746	ENOG4105V9J	phenylacetic acid degradation operon negative regulatory protein
APASM_0748	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
APASM_0749	ENOG4105C5Q	Transcriptional regulator
APASM_0752	ENOG4107QPH	glycogen) synthase
APASM_0753	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
APASM_0756	ENOG4105C0H	protease
APASM_0757	ENOG4105UTW	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
APASM_0761	ENOG4105CJW	magnesium transporter
APASM_0775	ENOG4105D7N	magnesium and cobalt transport protein CorA
APASM_0783	ENOG4105C1J	atp-dependent rna helicase
APASM_0790	ENOG4106HB6	Alpha beta hydrolase
APASM_0794	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
APASM_0796	ENOG4108IFG	nitrite reductase, (NAD(P)H)
APASM_0798	ENOG4105DQQ	Major facilitator superfamily MFS_1
APASM_0800	ENOG4107QZF	nitrite reductase NADPH large subunit
APASM_0801	ENOG4107QZF	nitrite reductase NADPH large subunit
APASM_0805	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
APASM_0806	ENOG4106F60	Histidine kinase
APASM_0813	ENOG4105C4R	Atp-dependent dna helicase
APASM_0816	ENOG4105DTD	Dehydrogenase
APASM_0817	ENOG4106NZI	LysR family Transcriptional regulator
APASM_0821	ENOG4105K70	DNA-binding protein
APASM_0825	ENOG4105C1V	Peptidase, M16
APASM_0827	ENOG4105E2R	ROK family
APASM_0833	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
APASM_0842	ENOG4105CVJ	phosphoglycerate mutase
APASM_0850	ENOG4108YS0	lipoprotein YafL
APASM_0855	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
APASM_0859	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
APASM_0861	ENOG4108UCS	ABC, transporter
APASM_0865	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
APASM_0866	ENOG4105CRK	lysyL-tRNA synthetase
APASM_0868	ENOG4105C4K	Nad synthetase
APASM_0869	ENOG4105C5F	glutamine synthetase
APASM_0874	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
APASM_0877	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
APASM_0884	ENOG4105WBQ	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
APASM_0896	ENOG4105DJZ	UPF0182 protein
APASM_0898	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
APASM_0899	ENOG4105CAK	Cell division ATP-binding protein ftsE
APASM_0900	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
APASM_0901	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
APASM_0902	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_0903	ENOG4105ENE	Histidine kinase
APASM_0904	ENOG4105CQ7	ATP-dependent helicase
APASM_0906	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
APASM_0907	ENOG4105C6X	Major Facilitator
APASM_0909	ENOG4105DZS	Phenylacetate-CoA ligase
APASM_0927	ENOG4105C0D	helicase
APASM_0929	ENOG4108I5C	dEAD DEAH box helicase
APASM_0930	ENOG4105C4R	Atp-dependent dna helicase
APASM_0938	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
APASM_0939	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
APASM_0942	ENOG4105ETE	Transcriptional regulator (LacI family
APASM_0943	ENOG4105IK6	Terpene synthase metal-binding domain-containing protein
APASM_0948	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
APASM_0949	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
APASM_0950	ENOG4105CR5	Class II aldolase adducin family protein
APASM_0951	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
APASM_0953	ENOG4105BZ9	Cytochrome C oxidase, subunit I
APASM_0954	ENOG4105EAC	phosphoserine phosphatase
APASM_0958	ENOG4105DZQ	phospholipase D Transphosphatidylase
APASM_0966	ENOG4108RWI	nicotinamidase
APASM_0967	ENOG4107RKP	Nicotinate phosphoribosyltransferase
APASM_0968	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
APASM_0974	ENOG4108RQ5	Beta-lactamase domain-containing protein
APASM_0975	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
APASM_0977	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
APASM_0978	ENOG4108RQ5	Beta-lactamase domain-containing protein
APASM_0982	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
APASM_0983	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
APASM_0987	ENOG4105DEN	Luciferase family
APASM_0988	ENOG4105H3G	oxidoreductase
APASM_0989	ENOG4107T5V	SNARE associated Golgi
APASM_0998	ENOG4108UB4	uncharacterized protein ygjQ
APASM_0999	ENOG4107TB5	TRANSCRIPTIONal
APASM_1000	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
APASM_1002	ENOG4105DFW	ABC transporter
APASM_1005	ENOG4105VEQ	Cold shock protein
APASM_1007	ENOG4105EX0	alpha-galactosidase
APASM_1009	ENOG4107XWB	Zinc finger, swim domain protein
APASM_1010	ENOG4105C0D	helicase
APASM_1018	ENOG4105C5H	ABC transporter
APASM_1019	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
APASM_1021	ENOG4105ECQ	AraC Family Transcriptional Regulator
APASM_1023	ENOG4105DE4	1-phosphofructokinase
APASM_1025	ENOG4105DM4	PTS System
APASM_1032	ENOG4107VWK	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
APASM_1037	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
APASM_1038	ENOG4105DMF	Dehydrogenase
APASM_1045	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
APASM_1047	ENOG4105C26	Dehydrogenase
APASM_1051	ENOG4107RR1	TRANSCRIPTIONal
APASM_1052	ENOG4105C26	Dehydrogenase
APASM_1054	ENOG4105E2D	ec 3.2.1.52
APASM_1061	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
APASM_1062	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
APASM_1065	ENOG4106UW1	Major Facilitator superfamily
APASM_1067	ENOG4105E4J	Cytochrome c oxidase caa3-type, assembly factor ctag-related protein
APASM_1075	ENOG4105C7I	Dehydrogenase
APASM_1080	ENOG4105CG3	alpha amylase, catalytic region
APASM_1082	ENOG4105D8X	mechanosensitive ion channel
APASM_1087	ENOG4109057	
APASM_1089	ENOG4105MC2	DSBA oxidoreductase
APASM_1097	ENOG4107V2S	Transcriptional regulator
APASM_1098	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
APASM_1099	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
APASM_1100	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
APASM_1103	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
APASM_1112	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
APASM_1113	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
APASM_1137	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
APASM_1138	ENOG4105CJ1	ABC, transporter
APASM_1140	ENOG4105HAC	ABC-2 type transporter
APASM_1147	ENOG4107QIZ	NADH dehydrogenase
APASM_1153	ENOG4105C03	ribonuclease
APASM_1153	ENOG4105C03	ribonuclease
APASM_1154	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
APASM_1155	ENOG4105K46	50S ribosomal protein l27
APASM_1156	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
APASM_1157	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
APASM_1158	ENOG4105CSH	Transporter
APASM_1159	ENOG4105KNA	-acetyltransferase
APASM_1160	ENOG4105C9U	ATP-dependent DNA helicase RecQ
APASM_1163	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
APASM_1167	ENOG4105EPR	degv family
APASM_1168	ENOG4105KQC	Competence protein
APASM_1169	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
APASM_1173	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
APASM_1183	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
APASM_1186	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
APASM_1190	ENOG4105CUB	amino acid
APASM_1192	ENOG4105CB2	alcohol dehydrogenase
APASM_1199	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
APASM_1200	ENOG4108IY8	ABC, transporter
APASM_1206	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
APASM_1208	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
APASM_1209	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
APASM_1213	ENOG4108YIQ	Alpha beta hydrolase
APASM_1214	ENOG4107YU2	histidine triad (hIT) protein
APASM_1217	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
APASM_1223	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
APASM_1224	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
APASM_1225	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
APASM_1234	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
APASM_1236	ENOG4107B2H	carbonic anhydrase
APASM_1239	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
APASM_1241	ENOG4105EC3	peptidase S51, dipeptidase E
APASM_1242	ENOG4108KPJ	rna polymerase sigma factor
APASM_1243	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
APASM_1249	ENOG4105CNU	cell division protein FtsK
APASM_1257	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
APASM_1258	ENOG4107TB5	TRANSCRIPTIONal
APASM_1261	ENOG4108ZJ4	polysaccharide deacetylase
APASM_1264	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
APASM_1269	ENOG41083YR	Protein CrcB homolog
APASM_1270	ENOG41083TI	Protein CrcB homolog
APASM_1272	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
APASM_1283	ENOG4105CJA	serine threonine protein kinase
APASM_1286	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
APASM_1287	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
APASM_1292	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
APASM_1298	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
APASM_1302	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
APASM_1304	ENOG4107S9F	NmrA family
APASM_1311	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
APASM_1313	ENOG4105CM2	brancheD-chain amino acid aminotransferase
APASM_1314	ENOG410813T	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
APASM_1316	ENOG4108YZT	Adenosylcobinamide kinase
APASM_1317	ENOG4105CPC	Aldo Keto reductase
APASM_1325	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
APASM_1326	ENOG4108ZRS	Part of cytochrome c oxidase, its function is
APASM_1327	ENOG4105CEY	Amp-dependent synthetase and ligase
APASM_1329	ENOG4107S1N	anthranilate phosphoribosyltransferase
APASM_1332	ENOG4105CCU	oxidase (Subunit III)
APASM_1333	ENOG4107UDY	cytochrome C
APASM_1335	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
APASM_1341	ENOG4105JNK	Glycosyl transferase (Group 1
APASM_1346	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
APASM_1348	ENOG4105DKQ	ROK family
APASM_1352	ENOG4105E9Q	Acyl-transferase
APASM_1354	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
APASM_1356	ENOG4105KYH	transcriptional regulatory protein
APASM_1357	ENOG41090CE	integral membrane protein
APASM_1361	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
APASM_1366	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
APASM_1373	ENOG4107QRT	dEAD DEAH box helicase
APASM_1375	ENOG4108KBA	Acts as a chaperone (By similarity)
APASM_1376	ENOG4108HH4	Major Facilitator Superfamily
APASM_1379	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
APASM_1380	ENOG4105KC9	Modulates RecA activity (By similarity)
APASM_1382	ENOG4108UHU	Aldolase
APASM_1383	ENOG4105C01	Dihydroxy-acid dehydratase
APASM_1388	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
APASM_1392	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
APASM_1394	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
APASM_1396	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
APASM_1398	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
APASM_1401	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
APASM_1402	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
APASM_1404	ENOG4105C99	atpase involved in dna repair
APASM_1406	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
APASM_1408	ENOG4105DHQ	Histidine kinase
APASM_1409	ENOG4108PYU	two-component system response regulator
APASM_1410	ENOG4105CDA	abc transporter atp-binding protein
APASM_1412	ENOG4108Q1T	ABC transporter
APASM_1413	ENOG4105DRP	amino acid AbC transporter
APASM_1419	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
APASM_1420	ENOG4105F8D	glycoside hydrolase family 4
APASM_1421	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
APASM_1422	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
APASM_1424	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
APASM_1425	ENOG4105CMR	udp-glucose 4-epimerase
APASM_1427	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
APASM_1429	ENOG4105KHC	sulfurtransferase
APASM_1432	ENOG4105DGU	Histone deacetylase
APASM_1434	ENOG4107UBR	Extracellular solute-binding protein family 3
APASM_1435	ENOG4105FDP	GntR family transcriptional regulator
APASM_1439	ENOG4105E0Y	RtcB Protein
APASM_1449	ENOG4105E9Z	Nad-dependent epimerase dehydratase
APASM_1452	ENOG4105EQX	glucarate dehydratase
APASM_1456	ENOG4107GFK	fumarate
APASM_1459	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
APASM_1460	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
APASM_1463	ENOG4105D7K	pfkb domain protein
APASM_1464	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
APASM_1468	ENOG4105DFW	ABC transporter
APASM_1469	ENOG4105C2J	ABC transporter
APASM_1470	ENOG4108HWW	ABC transporter
APASM_1482	ENOG4107VEG	TrkA-N domain protein
APASM_1483	ENOG4105C0X	amino acid
APASM_1484	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
APASM_1485	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
APASM_1487	ENOG4105F44	Two component transcriptional regulator, winged helix family
APASM_1488	ENOG4106F60	Histidine kinase
APASM_1504	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
APASM_1505	ENOG4105CHU	acetyl-coa acetyltransferase
APASM_1509	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
APASM_1510	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_1513	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
APASM_1514	ENOG4105C1Q	protoporphyrinogen oxidase
APASM_1515	ENOG4107JTW	chlorite dismutase
APASM_1521	ENOG4105E18	UPF0276 protein
APASM_1527	ENOG4105E0X	reductase
APASM_1532	ENOG4105C1G	acyl-Coa dehydrogenase
APASM_1533	ENOG4105C1G	acyl-Coa dehydrogenase
APASM_1534	ENOG4105DQE	DNA ligase
APASM_1542	ENOG4107AQZ	Membrane
APASM_1547	ENOG4105C5H	ABC transporter
APASM_1549	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
APASM_1550	ENOG4105C8Y	Acetylornithine aminotransferase
APASM_1555	ENOG4108KGH	TRANSCRIPTIONal
APASM_1558	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
APASM_1560	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
APASM_1563	ENOG4105C1G	acyl-Coa dehydrogenase
APASM_1568	ENOG4105YA8	Transcriptional regulator
APASM_1575	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
APASM_1577	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
APASM_1578	ENOG4107S91	Sodium hydrogen exchanger
APASM_1580	ENOG4105CAT	Cytidine monophosphate kinase
APASM_1582	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
APASM_1583	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_1587	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
APASM_1601	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
APASM_1604	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APASM_1614	ENOG4105BZ1	(ABC) transporter
APASM_1623	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
APASM_1625	ENOG4105C8Y	Acetylornithine aminotransferase
APASM_1628	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
APASM_1630	ENOG4108SHN	Glycosyl transferase, family 2
APASM_1636	ENOG4105CJ1	ABC, transporter
APASM_1674	ENOG4105BZU	Histidine kinase
APASM_1675	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
APASM_1678	ENOG4105EX0	alpha-galactosidase
APASM_1684	ENOG4108IV0	ABC, transporter
APASM_1685	ENOG4105C0Z	ABC transporter
APASM_1688	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
APASM_1690	ENOG4105EGE	secreted protein
APASM_1694	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
APASM_1695	ENOG4105C3U	ABC transporter
APASM_1702	ENOG4105KAV	tspo and mbr like protein
APASM_1704	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
APASM_1705	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
APASM_1706	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
APASM_1707	ENOG4105BZU	Histidine kinase
APASM_1710	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
APASM_1711	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
APASM_1712	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
APASM_1713	ENOG4108ZR3	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)
APASM_1715	ENOG4105CUT	histidyl-tRNA synthetase
APASM_1722	ENOG4107QX3	carboxylase
APASM_1723	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
APASM_1726	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
APASM_1727	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
APASM_1728	ENOG4105C9M	aspartyl-trna synthetase
APASM_1732	ENOG4105EDW	glycosyl transferase, family 39
APASM_1734	ENOG4105BZU	Histidine kinase
APASM_1735	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
APASM_1737	ENOG4105FXM	Copper resistance protein
APASM_1740	ENOG4105D3Q	Sugar transferase
APASM_1741	ENOG4107TYG	Oxidoreductase domain-containing protein
APASM_1742	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
APASM_1743	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
APASM_1744	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
APASM_1747	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
APASM_1752	ENOG4107RGC	Glycosyl transferase, family 2
APASM_1762	ENOG4108W2P	Methyl-accepting chemotaxis
APASM_1765	ENOG41082BV	acetyltransferase
APASM_1771	ENOG4105CPC	Aldo Keto reductase
APASM_1772	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
APASM_1773	ENOG4105E39	Enoyl-CoA hydratase
APASM_1778	ENOG4107S2Z	UPF0761 membrane protein
APASM_1781	ENOG4105CDA	abc transporter atp-binding protein
APASM_1782	ENOG4108HW4	amino acid AbC transporter
APASM_1784	ENOG41080RH	Thioredoxin
APASM_1786	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
APASM_1790	ENOG41081F0	Precorrin-8x methylmutase
APASM_1791	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
APASM_1792	ENOG4105CTK	cobaltochelatase, cobn subunit
APASM_1795	ENOG4105DRS	transport system, permease
APASM_1797	ENOG4105ETE	Transcriptional regulator (LacI family
APASM_1798	ENOG4108HMN	Caspase domain
APASM_1799	ENOG4105E2R	ROK family
APASM_1807	ENOG41086D8	Transcriptional regulator
APASM_1810	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
APASM_1819	ENOG41082YX	Transcriptional regulator, arsr family
APASM_1826	ENOG4107TT5	NLP P60 protein
APASM_1830	ENOG4105ETE	Transcriptional regulator (LacI family
APASM_1831	ENOG4105ETE	Transcriptional regulator (LacI family
APASM_1832	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
APASM_1834	ENOG4105I82	acetyl xylan esterase
APASM_1839	ENOG4105CHP	RNA polymerase
APASM_1845	ENOG4105CAY	ferredoxin--nadp reductase
APASM_1847	ENOG4105G6Z	alkaline phosphatase
APASM_1851	ENOG4108J20	pectate lyase
APASM_1853	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
APASM_1855	ENOG4105CXK	mandelate racemase muconate lactonizing
APASM_1858	ENOG4106T9R	serine protease
APASM_1860	ENOG41062B0	ABC transporter, permease
APASM_1861	ENOG4107R9N	ABC transporter
APASM_1862	ENOG4105C2J	ABC transporter
APASM_1863	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
APASM_1866	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
APASM_1867	ENOG4105ETE	Transcriptional regulator (LacI family
APASM_1868	ENOG4105EF1	ribulokinase
APASM_1870	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
APASM_1871	ENOG4105DFW	ABC transporter
APASM_1873	ENOG4108HWW	ABC transporter
APASM_1876	ENOG4105CX8	fg-gap repeat protein
APASM_1879	ENOG4105ETE	Transcriptional regulator (LacI family
APASM_1884	ENOG4108K8S	endonuclease I
APASM_1886	ENOG4105BZU	Histidine kinase
APASM_1890	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
APASM_1891	ENOG410903U	zinc ion binding
APASM_1892	ENOG4105DEG	Vwa containing coxe family protein
APASM_1893	ENOG4105RD5	
APASM_1894	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
APASM_1895	ENOG4108KDT	Molybdate metabolism regulator
APASM_1896	ENOG4108KDT	Molybdate metabolism regulator
APASM_1897	ENOG4108KDT	Molybdate metabolism regulator
APASM_1898	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
APASM_1904	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
APASM_1907	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APASM_1908	ENOG4105CSR	polyphosphate kinase 2
APASM_1909	ENOG4105Y3U	Transglycosylase-associated protein
APASM_1925	ENOG4107QRI	Phosphoketolase
APASM_1926	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
APASM_1927	ENOG4105D9P	serine threonine protein kinase
APASM_1929	ENOG4105EXC	Acyl-transferase
APASM_1931	ENOG4105EDW	glycosyl transferase, family 39
APASM_1936	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
APASM_1938	ENOG4105CGD	Nad-dependent epimerase dehydratase
APASM_1940	ENOG4108KXV	response regulator
APASM_1945	ENOG4105BZU	Histidine kinase
APASM_1947	ENOG4108M15	ABC transporter
APASM_1960	ENOG4105C57	major facilitator superfamily
APASM_1976	ENOG4105EJ2	Transcriptional regulator
APASM_1978	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
APASM_1986	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
APASM_1988	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
APASM_1989	ENOG4105ETE	Transcriptional regulator (LacI family
APASM_1996	ENOG4105PAD	Hydrolase
APASM_1999	ENOG4107U9T	Pfam:Ribonuclease_BN
APASM_2001	ENOG4105C8Y	Acetylornithine aminotransferase
APASM_2002	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
APASM_2005	ENOG4105D49	3-dehydroquinate synthase
APASM_2007	ENOG4108PVU	Nucleotidyl transferase
APASM_2010	ENOG4107R9S	Malate synthase
APASM_2014	ENOG4105BZU	Histidine kinase
APASM_2015	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_2017	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
APASM_2021	ENOG4105KF0	sporulation and cell division protein, SsgA
APASM_2022	ENOG4105K6V	RNA polymerase
APASM_2025	ENOG4107T65	Integrase
APASM_2051	ENOG4105GFG	DUF218 domain
APASM_2058	ENOG4108JPW	Aminotransferase
APASM_2060	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
APASM_2064	ENOG4107QXX	ABC transporter
APASM_2065	ENOG4105C85	amino acid
APASM_2067	ENOG4105BZ1	(ABC) transporter
APASM_2069	ENOG4105DU1	integral membrane protein, terc
APASM_2072	ENOG4105R3A	Nitrate reductase
APASM_2073	ENOG4108IUE	nitrate reductase beta subunit
APASM_2081	ENOG41065HY	1,4-beta-cellobiosidase
APASM_2083	ENOG4108HQR	Glycine betaine
APASM_2084	ENOG4105E90	ABC transporter
APASM_2085	ENOG4108IJ8	ABC transporter
APASM_2086	ENOG4105E90	ABC transporter
APASM_2090	ENOG4105E0C	molybdate abc transporter
APASM_2091	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
APASM_2096	ENOG4107Y2X	deaminase
APASM_2106	ENOG4105RHY	Pfam:UPF0157
APASM_2108	ENOG4105K4I	Scp-like extracellular
APASM_2109	ENOG4105CUB	amino acid
APASM_2111	ENOG4108Z86	Glutamine amidotransferase
APASM_2114	ENOG41073TP	transcriptional regulator
APASM_2122	ENOG4105C22	threonyL-tRNA synthetase
APASM_2126	ENOG4107YQ3	lipid a biosynthesis lauroyl acyltransferase
APASM_2127	ENOG4105E2K	Glycosyl transferase (Group 1
APASM_2128	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
APASM_2129	ENOG4105KWG	Pfam:DUF1696
APASM_2132	ENOG4107RNN	dihydropyrimidinase (EC 3.5.2.2)
APASM_2134	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
APASM_2138	ENOG4108JPW	Aminotransferase
APASM_2139	ENOG4105C26	Dehydrogenase
APASM_2142	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
APASM_2143	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
APASM_2144	ENOG4105CDY	transcriptional regulatory protein
APASM_2147	ENOG4108R86	Transcriptional regulator
APASM_2148	ENOG4105C57	major facilitator superfamily
APASM_2150	ENOG4106A3M	Cytochrome p-450
APASM_2156	ENOG4105D1K	glutamate--cysteine ligase
APASM_2157	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
APASM_2159	ENOG41067HS	methyltransferase
APASM_2167	ENOG4107QM5	aconitate hydratase
APASM_2168	ENOG4105FDK	ABC transporter
APASM_2171	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
APASM_2173	ENOG4105CEY	Amp-dependent synthetase and ligase
APASM_2174	ENOG4105ZXU	NLP P60 protein
APASM_2177	ENOG4105FQ6	thiopurine methyltransferase
APASM_2178	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
APASM_2183	ENOG4105BZU	Histidine kinase
APASM_2198	ENOG4105K5B	UPF0225 protein
APASM_2199	ENOG4108W9Q	Endoglucanase (EC 3.2.1.4)
APASM_2200	ENOG4105CYP	glycoside hydrolase, family
APASM_2202	ENOG4105ETE	Transcriptional regulator (LacI family
APASM_2205	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
APASM_2206	ENOG4105C4C	beta-galactosidase
APASM_2208	ENOG4105VF7	tolerance protein
APASM_2212	ENOG4105CQB	FAD linked oxidase domain protein
APASM_2214	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
APASM_2215	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
APASM_2218	ENOG4105EMU	Dehydrogenase
APASM_2222	ENOG41065HY	1,4-beta-cellobiosidase
APASM_2223	ENOG4105EET	magnesium chelatase
APASM_2227	ENOG4108NVR	Methyl-accepting chemotaxis
APASM_2229	ENOG4105BZ9	Cytochrome C oxidase, subunit I
APASM_2231	ENOG4105C8N	cysteinyl-tRNA synthetase
APASM_2232	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
APASM_2237	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
APASM_2238	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
APASM_2239	ENOG4105ES5	Histidine kinase
APASM_2241	ENOG4105C3R	Methionine synthase
APASM_2242	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
APASM_2245	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
APASM_2246	ENOG4107FW0	short-chain dehydrogenase reductase
APASM_2248	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
APASM_2249	ENOG4105RK9	auxin efflux carrier
APASM_2255	ENOG4105CHR	reductase
APASM_2256	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_2258	ENOG4105IIP	Membrane
APASM_2263	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
APASM_2264	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_2265	ENOG4105BZU	Histidine kinase
APASM_2269	ENOG4105PTV	Nudix Hydrolase
APASM_2271	ENOG4105E5F	proteasome
APASM_2272	ENOG4105WFD	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (By similarity)
APASM_2273	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
APASM_2274	ENOG4105F7N	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
APASM_2275	ENOG4105EMU	Dehydrogenase
APASM_2277	ENOG4107SM8	Adenylate Guanylate cyclase
APASM_2279	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
APASM_2282	ENOG4107TMB	Transcriptional regulator
APASM_2283	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
APASM_2290	ENOG4105J0Q	Transcriptional regulator
APASM_2293	ENOG4105BZU	Histidine kinase
APASM_2303	ENOG41090MY	MarR family Transcriptional regulator
APASM_2304	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
APASM_2306	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
APASM_2310	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
APASM_2314	ENOG4108UZX	fmn reductase
APASM_2315	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
APASM_2320	ENOG4105BZ1	(ABC) transporter
APASM_2326	ENOG4105DKQ	ROK family
APASM_2329	ENOG4105QE3	oxidoreductase
APASM_2337	ENOG4108NBA	ATP-dependent carboxylate-amine ligase (By similarity)
APASM_2338	ENOG4105DEN	Luciferase family
APASM_2339	ENOG4105I8F	Histidine kinase
APASM_2342	ENOG4105D7B	Flagellar biosynthesis protein flha
APASM_2344	ENOG4108VYJ	response regulator receiver protein
APASM_2346	ENOG4108VYJ	response regulator receiver protein
APASM_2347	ENOG4105BZU	Histidine kinase
APASM_2348	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
APASM_2351	ENOG4105YFD	chemotaxis, protein
APASM_2352	ENOG4105CBS	Chea signal transduction histidine kinase
APASM_2356	ENOG4105D00	flagellar biosynthetic protein flhB
APASM_2357	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
APASM_2358	ENOG4105VS8	Flagellar biosynthetic protein fliq
APASM_2359	ENOG4105CN7	Flagellar biosynthetic protein FliP
APASM_2361	ENOG4105DD5	Flagellar motor switch protein
APASM_2364	ENOG4105ER2	Ompa motb domain protein
APASM_2365	ENOG4105E14	MotA TolQ exbB proton channel
APASM_2367	ENOG4108JQA	flagellar
APASM_2370	ENOG4105E4C	Lytic transglycosylase catalytic
APASM_2374	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
APASM_2375	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
APASM_2376	ENOG41084Q6	flagellar hook-basal body complex protein fliE
APASM_2377	ENOG4108ZC9	flagellar basal-body rod protein flgc
APASM_2380	ENOG4105MQ3	flagellar protein FliS
APASM_2382	ENOG4105I03	Flagellin
APASM_2383	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APASM_2385	ENOG4105E1Q	flagellar hook-associated protein
APASM_2387	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
APASM_2388	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
APASM_2389	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
APASM_2394	ENOG4105BZU	Histidine kinase
APASM_2396	ENOG4105BZU	Histidine kinase
APASM_2397	ENOG4105BZU	Histidine kinase
APASM_2402	ENOG4105FS7	Transcriptional regulator
APASM_2410	ENOG4105EW9	transcriptional regulator AsnC family
APASM_2411	ENOG4107SFI	Major Facilitator superfamily
APASM_2417	ENOG4105CHR	reductase
APASM_2419	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
APASM_2430	ENOG4105ETE	Transcriptional regulator (LacI family
APASM_2432	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
APASM_2433	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
APASM_2435	ENOG4105CIG	ABC transporter
APASM_2436	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_2442	ENOG41068KF	Universal stress protein
APASM_2443	ENOG4105F1A	Pyruvate formate-lyase
APASM_2449	ENOG4105CHR	reductase
APASM_2454	ENOG4105CQB	FAD linked oxidase domain protein
APASM_2463	ENOG4107RH8	nuclease SbcCD subunit D
APASM_2469	ENOG4106A3M	Cytochrome p-450
APASM_2470	ENOG4105C5Q	Transcriptional regulator
APASM_2480	ENOG4105DEF	Extracellular solute-binding protein, family 5
APASM_2482	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
APASM_2483	ENOG4105KVH	Transcriptional regulator
APASM_2487	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
APASM_2488	ENOG4105I8F	Histidine kinase
APASM_2492	ENOG4108WYP	Transcriptional regulator
APASM_2499	ENOG4105DU1	integral membrane protein, terc
APASM_2500	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
APASM_2516	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
APASM_2525	ENOG4105GRZ	Ycii-related protein
APASM_2526	ENOG4105CHP	RNA polymerase
APASM_2534	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
APASM_2535	ENOG4105DEG	Vwa containing coxe family protein
APASM_2540	ENOG4105CH6	catalase
APASM_2542	ENOG4105JAB	phenazine biosynthesis protein, phzf family
APASM_2553	ENOG4107Q25	Serine Threonine protein kinase
APASM_2556	ENOG4105EPJ	extracellular solute-binding protein family 1
APASM_2560	ENOG4105S8Q	sugar efflux transporter
APASM_2562	ENOG4105CQR	helicase
APASM_2578	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
APASM_2601	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
APASM_2605	ENOG4105ETE	Transcriptional regulator (LacI family
APASM_2618	ENOG4108UVJ	appr-1-p processing domain protein
APASM_2619	ENOG4107ZXU	DSBA oxidoreductase
APASM_2632	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
APASM_2633	ENOG4108IG5	Transcriptional regulator
APASM_2634	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
APASM_2635	ENOG4105ECR	NmrA family
APASM_2643	ENOG4105NPE	arsR family transcriptional regulator
APASM_2644	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
APASM_2649	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
APASM_2651	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
APASM_2655	ENOG41062D9	Histidine kinase
APASM_2659	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
APASM_2667	ENOG4107SQD	Transcriptional regulator, GntR family
APASM_2669	ENOG4105CMT	Dihydroxyacetone kinase
APASM_2670	ENOG4107YVI	ribose 5-phosphate isomerase
APASM_2671	ENOG4105CP7	Triose-phosphate isomerase
APASM_2672	ENOG4108KFM	Xylose Isomerase Domain-Containing protein
APASM_2673	ENOG4106J7G	oxidoreductase
APASM_2676	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
APASM_2682	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
APASM_2684	ENOG4105CIK	Amidinotransferase
APASM_2688	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
APASM_2704	ENOG4105C57	major facilitator superfamily
APASM_2711	ENOG4105CEY	Amp-dependent synthetase and ligase
APASM_2715	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
APASM_2720	ENOG4108JA1	polyketide synthase
APASM_2724	ENOG4105C19	ABC transporter
APASM_2733	ENOG4105EHG	Permease protein
APASM_2734	ENOG4105E0A	ABC, transporter
APASM_2742	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
APASM_2745	ENOG4105E0A	ABC, transporter
APASM_2746	ENOG4105TVJ	transport system, permease
APASM_2747	ENOG4105DQ5	transport system permease protein
APASM_2749	ENOG4105Q26	Siderophore-interacting protein
APASM_2750	ENOG4105WQI	isochorismatase
APASM_2751	ENOG4105WQI	isochorismatase
APASM_2752	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
APASM_2753	ENOG4105E4F	Isochorismate synthase
APASM_2754	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
APASM_2756	ENOG4105EHG	Permease protein
APASM_2757	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
APASM_2759	ENOG4105VMP	Transcriptional regulator
APASM_2762	ENOG4108ZGX	Histidine kinase
APASM_2763	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_2769	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
APASM_2772	ENOG4108IUX	(ABC) transporter
APASM_2773	ENOG4105RHA	ABC transporter, permease
APASM_2775	ENOG4108W2P	Methyl-accepting chemotaxis
APASM_2784	ENOG41079KZ	Major Facilitator Superfamily
APASM_2786	ENOG4105CPN	adenine deaminase
APASM_2787	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_2789	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
APASM_2803	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
APASM_2804	ENOG4105YIP	Tetr family transcriptional regulator
APASM_2808	ENOG4106UW1	Major Facilitator superfamily
APASM_2810	ENOG4106NZI	LysR family Transcriptional regulator
APASM_2811	ENOG4105C7B	Threonine dehydratase
APASM_2813	ENOG4105C26	Dehydrogenase
APASM_2817	ENOG4105EYF	MMPL domain protein
APASM_2836	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_2844	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
APASM_2845	ENOG4105CMR	udp-glucose 4-epimerase
APASM_2848	ENOG4105CJ1	ABC, transporter
APASM_2854	ENOG4105ETE	Transcriptional regulator (LacI family
APASM_2856	ENOG4105BZ7	extracellular solute-binding protein family 1
APASM_2858	ENOG4105EG2	ABC transporter, permease
APASM_2861	ENOG4107SYN	Glycosyl hydrolases family 43
APASM_2863	ENOG4106JDR	secreted
APASM_2866	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_2870	ENOG4105C7K	acetolactate synthase
APASM_2871	ENOG4105CH2	amidohydrolase
APASM_2872	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
APASM_2875	ENOG4105D38	putrescine abc transporter
APASM_2876	ENOG4105F38	ABC transporter, permease
APASM_2877	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
APASM_2879	ENOG4105EMU	Dehydrogenase
APASM_2883	ENOG4108R86	Transcriptional regulator
APASM_2887	ENOG4105EKC	
APASM_2889	ENOG4105CNA	YD repeat protein
APASM_2893	ENOG4105EHG	Permease protein
APASM_2894	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
APASM_2897	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
APASM_2901	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
APASM_2912	ENOG4105KPY	Small multidrug resistance protein
APASM_2921	ENOG4105ECM	Sensor protein basS pmrB
APASM_2923	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
APASM_2925	ENOG4105CEY	Amp-dependent synthetase and ligase
APASM_2935	ENOG4105BZU	Histidine kinase
APASM_2941	ENOG4105KVH	Transcriptional regulator
APASM_2942	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
APASM_2944	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
APASM_2948	ENOG4108JQ1	Dehydrogenase
APASM_2979	ENOG4105F0K	SARP family transcriptional regulator
APASM_2989	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
APASM_2990	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
APASM_2991	ENOG4108KDT	Molybdate metabolism regulator
APASM_2992	ENOG4105C87	Aminotransferase class I and II
APASM_2997	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
APASM_3001	ENOG41067SE	Tetr family transcriptional regulator
APASM_3009	ENOG4105HS6	binding-protein-dependent transport systems inner membrane Component
APASM_3010	ENOG4105I1K	ABC transporter
APASM_3011	ENOG4105CJQ	hydrolase, family 31
APASM_3013	ENOG4105ETE	Transcriptional regulator (LacI family
APASM_3018	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
APASM_3025	ENOG4108JGH	Tetr family transcriptional regulator
APASM_3027	ENOG4108Z6Z	Transcriptional regulator
APASM_3028	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_3030	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
APASM_3031	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
APASM_3034	ENOG4105CG3	alpha amylase, catalytic region
APASM_3041	ENOG4105Q26	Siderophore-interacting protein
APASM_3045	ENOG4105JAB	phenazine biosynthesis protein, phzf family
APASM_3048	ENOG4108KDT	Molybdate metabolism regulator
APASM_3055	ENOG4108MWI	inositol mono-phosphatase
APASM_3057	ENOG4105BZ1	(ABC) transporter
APASM_3058	ENOG4105BZ1	(ABC) transporter
APASM_3070	ENOG41080R8	Conserved Protein
APASM_3071	ENOG4107QR9	Iron-sulfur cluster binding protein
APASM_3072	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
APASM_3073	ENOG4105FDP	GntR family transcriptional regulator
APASM_3075	ENOG4105C2J	ABC transporter
APASM_3077	ENOG4105CNN	ABC, transporter
APASM_3081	ENOG4105DET	Rhamnulokinase
APASM_3083	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
APASM_3085	ENOG4106NZI	LysR family Transcriptional regulator
APASM_3088	ENOG4105BZU	Histidine kinase
APASM_3090	ENOG4105DU6	RNA polymerase
APASM_3093	ENOG4106A3M	Cytochrome p-450
APASM_3102	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
APASM_3105	ENOG4105CAQ	asparagine synthetase
APASM_3109	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
APASM_3110	ENOG4108JPW	Aminotransferase
APASM_3111	ENOG4105C26	Dehydrogenase
APASM_3113	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
APASM_3122	ENOG4108NVR	Methyl-accepting chemotaxis
APASM_3123	ENOG4105C5Q	Transcriptional regulator
APASM_3124	ENOG4105DWP	Membrane
APASM_3126	ENOG4105EQ0	Major Facilitator superfamily
APASM_3135	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
APASM_3139	ENOG4105EX0	alpha-galactosidase
APASM_3142	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
APASM_3143	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
APASM_3145	ENOG4107SCK	Monooxygenase
APASM_3149	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
APASM_3150	ENOG4105DYW	oxidoreductase
APASM_3156	ENOG4105CV8	reductase
APASM_3157	ENOG4106NZI	LysR family Transcriptional regulator
APASM_3160	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
APASM_3162	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
APASM_3163	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
APASM_3169	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
APASM_3171	ENOG41061GT	Aldolase
APASM_3172	ENOG4105CPQ	Dehydrogenase
APASM_3175	ENOG4105CHH	sulfate transporter
APASM_3183	ENOG4107RN3	metallophosphoesterase
APASM_3188	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
APASM_3189	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
APASM_3191	ENOG4105M03	Domain of unknown function (DUF955)
APASM_3193	ENOG4105EYF	MMPL domain protein
APASM_3202	ENOG4105U5Y	Transcriptional regulator
APASM_3204	ENOG4105BZ1	(ABC) transporter
APASM_3212	ENOG4108XW1	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity (By similarity)
APASM_3215	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
APASM_3216	ENOG4105X96	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity)
APASM_3221	ENOG4105GRZ	Ycii-related protein
APASM_3225	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
APASM_3231	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
APASM_3234	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
APASM_3238	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
APASM_3248	ENOG4108W9Q	Endoglucanase (EC 3.2.1.4)
APASM_3249	ENOG4106R7G	Glycoside hydrolase family 5
APASM_3251	ENOG4105BZU	Histidine kinase
APASM_3252	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_3255	ENOG4108W9Q	Endoglucanase (EC 3.2.1.4)
APASM_3258	ENOG4105CHR	reductase
APASM_3259	ENOG4105CPC	Aldo Keto reductase
APASM_3263	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
APASM_3264	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
APASM_3281	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
APASM_3288	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
APASM_3291	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
APASM_3292	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
APASM_3303	ENOG4105D49	3-dehydroquinate synthase
APASM_3309	ENOG4108EUP	Glycosyl hydrolase family 62 
APASM_3311	ENOG4108W9Q	Endoglucanase (EC 3.2.1.4)
APASM_3312	ENOG4105ETE	Transcriptional regulator (LacI family
APASM_3317	ENOG4105E1F	short-chain dehydrogenase reductase
APASM_3320	ENOG4105BZU	Histidine kinase
APASM_3323	ENOG4105F6J	Alpha beta hydrolase fold
APASM_3324	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
APASM_3332	ENOG4105ECQ	AraC Family Transcriptional Regulator
APASM_3342	ENOG4105ETE	Transcriptional regulator (LacI family
APASM_3344	ENOG4105KVH	Transcriptional regulator
APASM_3349	ENOG4106HB6	Alpha beta hydrolase
APASM_3355	ENOG4105Y3U	Transglycosylase-associated protein
APASM_3356	ENOG4105EBR	Carboxylesterase
APASM_3357	ENOG4105CY0	Metallo-Beta-Lactamase
APASM_3363	ENOG4105DQ4	alcohol dehydrogenase
APASM_3366	ENOG4105NAE	bifunctional deaminase-reductase domain protein
APASM_3369	ENOG4105CPC	Aldo Keto reductase
APASM_3372	ENOG4107QRI	Phosphoketolase
APASM_3373	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
APASM_3384	ENOG4105DUM	transcriptional regulator, lysR family
APASM_3387	ENOG4107VFM	Dehydrogenase
APASM_3393	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
APASM_3400	ENOG4105FF5	Membrane
APASM_3401	ENOG4108SEA	Esterase
APASM_3403	ENOG4105CD3	dihydroorotase
APASM_3404	ENOG4108UYI	beta-alanyl-CoA ammonia lyase
APASM_3408	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
APASM_3414	ENOG4107W53	thymidine kinase
APASM_3417	ENOG4105DEU	major facilitator superfamily
APASM_3418	ENOG4105BZU	Histidine kinase
APASM_3421	ENOG4105FDF	Could be involved in DNA repair (By similarity)
APASM_3427	ENOG41082YX	Transcriptional regulator, arsr family
APASM_3439	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
APASM_3442	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
APASM_3443	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
APASM_3444	ENOG4105E98	transcriptional regulator DeoR family
APASM_3446	ENOG4108IRC	dna polymerase iii
APASM_3447	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
APASM_3454	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
APASM_3455	ENOG4105CHR	reductase
APASM_3458	ENOG4105CHR	reductase
APASM_3462	ENOG4105C1G	acyl-Coa dehydrogenase
APASM_3464	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
APASM_3466	ENOG4107QRA	Extracellular solute-binding protein, family 5
APASM_3468	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
APASM_3470	ENOG4105ETE	Transcriptional regulator (LacI family
APASM_3474	ENOG4105I1K	ABC transporter
APASM_3475	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
APASM_3488	ENOG4105CPC	Aldo Keto reductase
APASM_3496	ENOG4108PC0	lipolytic protein G-D-S-L family
APASM_3503	ENOG4107S1Q	Phosphatase
APASM_3507	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
APASM_3509	ENOG4105CT1	(ABC) transporter
APASM_3512	ENOG4108ZT1	Transcriptional regulator
APASM_3516	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
APASM_3518	ENOG4105CQ7	ATP-dependent helicase
APASM_3522	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
APASM_3523	ENOG4105DYW	oxidoreductase
APASM_3524	ENOG4105CPC	Aldo Keto reductase
APASM_3531	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
APASM_3533	ENOG4108KQI	regulatory protein luxr
APASM_3534	ENOG4107HP6	Transcriptional regulator
APASM_3546	ENOG4105F27	Major Facilitator
APASM_3550	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
APASM_3557	ENOG4105EMN	RNA polymerase sigma factor
APASM_3558	ENOG4107TB5	TRANSCRIPTIONal
APASM_3568	ENOG4105DSG	hydrolase family 43
APASM_3573	ENOG4108S01	response regulator
APASM_3575	ENOG4106A3M	Cytochrome p-450
APASM_3580	ENOG4105CEY	Amp-dependent synthetase and ligase
APASM_3581	ENOG4105C7B	Threonine dehydratase
APASM_3589	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
APASM_3592	ENOG4108JJB	ABC transporter
APASM_3597	ENOG4108K8K	Transcriptional regulator
APASM_3598	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
APASM_3599	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
APASM_3602	ENOG4106A3M	Cytochrome p-450
APASM_3605	ENOG4105CEY	Amp-dependent synthetase and ligase
APASM_3609	ENOG4105BZ1	(ABC) transporter
APASM_3616	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
APASM_3619	ENOG4105C8Y	Acetylornithine aminotransferase
APASM_3621	ENOG4105C26	Dehydrogenase
APASM_3628	ENOG4108UW5	maltose o-acetyltransferase
APASM_3634	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
APASM_3646	ENOG4105BZ1	(ABC) transporter
APASM_3650	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
APASM_3659	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
APASM_3661	ENOG4108RZE	Tetr family transcriptional regulator
APASM_3665	ENOG4105FS0	cytoplasmic membrane protein
APASM_3674	ENOG4105BZ9	Cytochrome C oxidase, subunit I
APASM_3680	ENOG4105G63	Type III effector Hrp-dependent
APASM_3681	ENOG4105FB2	class II Aldolase
APASM_3682	ENOG4105MVE	transcriptional regulator
APASM_3686	ENOG4108Q50	Histidine kinase
APASM_3689	ENOG4105M3Z	response regulator
APASM_3690	ENOG4105BZU	Histidine kinase
APASM_3692	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
APASM_3693	ENOG4105FUA	antagonist
APASM_3694	ENOG4107MMM	Anti-sigma-factor antagonist
APASM_3697	ENOG4105F95	Monooxygenase
APASM_3708	ENOG4105CWX	Alpha-1,2-mannosidase
APASM_3722	ENOG41067NU	
APASM_3733	ENOG4105F9V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
APASM_3740	ENOG4105EX0	alpha-galactosidase
APASM_3742	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
APASM_3744	ENOG4107YPT	transcriptional regulator
APASM_3746	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
APASM_3750	ENOG41081JD	Transcriptional regulator
APASM_3751	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
APASM_3762	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
APASM_3763	ENOG4105CPC	Aldo Keto reductase
APASM_3770	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
APASM_3771	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
APASM_3773	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
APASM_3774	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
APASM_3775	ENOG4105C1Q	protoporphyrinogen oxidase
APASM_3777	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
APASM_3782	ENOG4108KB0	deacetylase
APASM_3784	ENOG4107TYG	Oxidoreductase domain-containing protein
APASM_3786	ENOG4107EG8	signal transduction protein with EFhand domain
APASM_3787	ENOG4107QQG	Dehydrogenase
APASM_3793	ENOG4105CWX	Alpha-1,2-mannosidase
APASM_3794	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
APASM_3799	ENOG4107RDB	Major Facilitator
APASM_3811	ENOG4108VQR	secreted hydrolase
APASM_3813	ENOG4108KXV	response regulator
APASM_3815	ENOG4105VTR	Integrase
APASM_3823	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
APASM_3824	ENOG4107XR7	(6-pyruvoyl tetrahydrobiopterin) synthase
APASM_3829	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
APASM_3830	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
APASM_3831	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
APASM_3833	ENOG4105E6M	Sulphatase-modifying factor protein
APASM_3835	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
APASM_3839	ENOG4105DU0	nucleoside hydrolase
APASM_3843	ENOG4105DK0	Indole-3-glycerol phosphate synthase
APASM_3847	ENOG4108HMN	Caspase domain
APASM_3850	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
APASM_3879	ENOG4105C0W	non-ribosomal peptide synthetase
APASM_3887	ENOG4108W5M	transcriptional regulator
APASM_3900	ENOG4105NFX	aminoglycoside hydroxyurea antibiotic resistance kinase
APASM_3901	ENOG4105EHG	Permease protein
APASM_3904	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
APASM_3905	ENOG4105EHG	Permease protein
APASM_3921	ENOG4105MC2	DSBA oxidoreductase
APASM_3940	ENOG4108J20	pectate lyase
APASM_3941	ENOG4107S46	esterase, PHB depolymerase
APASM_3947	ENOG4105DQ4	alcohol dehydrogenase
APASM_3956	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
APASM_3957	ENOG4105M4P	Tetr family transcriptional regulator
APASM_3958	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
APASM_3961	ENOG4108RFG	Tetr family transcriptional regulator
APASM_3962	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
APASM_3964	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
APASM_3968	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
APASM_3970	ENOG4105CHF	Glutathione S-transferase
APASM_3975	ENOG4106JDR	secreted
APASM_3976	ENOG4105CAT	Cytidine monophosphate kinase
APASM_3981	ENOG4105BZU	Histidine kinase
APASM_3982	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_3996	ENOG4105F1N	DNA alkylation repair
APASM_3997	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
APASM_3998	ENOG4107NHD	transcriptional regulator
APASM_3999	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
APASM_4008	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
APASM_4015	ENOG4107TPY	serine threonine protein kinase
APASM_4020	ENOG4105CAY	ferredoxin--nadp reductase
APASM_4029	ENOG4105DIA	mandelate racemase muconate lactonizing
APASM_4035	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
APASM_4037	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_4038	ENOG4105BZU	Histidine kinase
APASM_4048	ENOG4107W6X	Transcriptional regulator
APASM_4050	ENOG4108IG5	Transcriptional regulator
APASM_4051	ENOG4105BZU	Histidine kinase
APASM_4052	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
APASM_4055	ENOG4107RBB	ABC transporter, permease
APASM_4070	ENOG4105F27	Major Facilitator
APASM_4074	ENOG4105CKK	Glycosyl transferase, family 2
APASM_4076	ENOG4105CIR	epoxide hydrolase
APASM_4082	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
APASM_4084	ENOG4105E1F	short-chain dehydrogenase reductase
APASM_4087	ENOG41068W2	Cytochrome p-450
APASM_4088	ENOG4108R6W	Transcriptional regulator, ARAC family
APASM_4091	ENOG4105CPQ	Dehydrogenase
APASM_4099	ENOG4105CEY	Amp-dependent synthetase and ligase
APASM_4104	ENOG4105E7U	AraC family transcriptional regulator
APASM_4114	ENOG4105C0D	helicase
APASM_4116	ENOG4105ETE	Transcriptional regulator (LacI family
APASM_4118	ENOG4105CXK	mandelate racemase muconate lactonizing
APASM_4123	ENOG4105EB3	Histidine kinase
APASM_4124	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
APASM_4130	ENOG4105EUB	pirin domain protein
APASM_4137	ENOG4107JC6	Membrane
APASM_4141	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
APASM_4143	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
APASM_4146	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
APASM_4147	ENOG4107258	Transcriptional regulator
APASM_4148	ENOG4105JSC	dimethylmenaquinone methyltransferase
APASM_4155	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
APASM_4166	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
APASM_4168	ENOG4107R05	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
APASM_4170	ENOG4105PDP	Short chain dehydrogenase
APASM_4174	ENOG4107U4H	Methyl-accepting chemotaxis
APASM_4176	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
APASM_4179	ENOG4105DUY	Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein
APASM_4186	ENOG4107SCK	Monooxygenase
APASM_4187	ENOG4108JPW	Aminotransferase
APASM_4191	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
APASM_4193	ENOG4105DXC	membrane
APASM_4194	ENOG4107YHX	fad dependent oxidoreductase
APASM_4202	ENOG4105ECY	inositol monophosphatase
APASM_4208	ENOG4106R7G	Glycoside hydrolase family 5
APASM_4210	ENOG4105CHH	sulfate transporter
APASM_4213	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
APASM_4223	ENOG410905P	Pyridoxamine 5-phosphate
APASM_4224	ENOG4108SV8	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity (By similarity)
APASM_4225	ENOG4106A3M	Cytochrome p-450
APASM_4226	ENOG4105C9U	ATP-dependent DNA helicase RecQ
APASM_4227	ENOG4107T94	Endo-14-beta-xylanase
APASM_4228	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
APASM_4230	ENOG4105DRS	transport system, permease
APASM_4232	ENOG4107FKK	extracellular solute-binding protein family 1
APASM_4234	ENOG4105CPC	Aldo Keto reductase
APASM_4238	ENOG4108IXY	short-chain dehydrogenase reductase
APASM_4245	ENOG4108UW5	maltose o-acetyltransferase
APASM_4248	ENOG4105CPF	Cell wall formation (By similarity)
APASM_4251	ENOG4108KK4	3-dehydroquinate synthase
APASM_4252	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_4253	ENOG4105BZU	Histidine kinase
APASM_4258	ENOG4108KDT	Molybdate metabolism regulator
APASM_4263	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
APASM_4267	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
APASM_4270	ENOG4105C3S	Mate efflux family protein
APASM_4273	ENOG41066UM	arsR family transcriptional regulator
APASM_4276	ENOG41082SX	arsR family transcriptional regulator
APASM_4278	ENOG410650H	(LipO)protein
APASM_4279	ENOG4105DBE	peroxidase
APASM_4282	ENOG4105CIR	epoxide hydrolase
APASM_4283	ENOG4105E0A	ABC, transporter
APASM_4284	ENOG4108IHU	transport system permease protein
APASM_4285	ENOG4105DQ5	transport system permease protein
APASM_4286	ENOG4105J76	Periplasmic binding protein
APASM_4287	ENOG4106T9R	serine protease
APASM_4290	ENOG4105CXN	decarboxylase
APASM_4298	ENOG4105CQB	FAD linked oxidase domain protein
APASM_4302	ENOG4107NQ8	LysR family Transcriptional regulator
APASM_4303	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
APASM_4304	ENOG4105C1G	acyl-Coa dehydrogenase
APASM_4307	ENOG4108K3Z	AraC family transcriptional regulator
APASM_4309	ENOG4107QY8	reductase
APASM_4315	ENOG4108JQ6	ABC transporter
APASM_4328	ENOG4105F7P	transcriptional regulator AsnC family
APASM_4330	ENOG4105EE5	Membrane protein terC
APASM_4332	ENOG41082JN	Transcriptional regulator
APASM_4334	ENOG4105DJ2	Major Facilitator Superfamily
APASM_4338	ENOG4105C2C	drug resistance transporter, Bcr CflA
APASM_4346	ENOG4105ETX	regulatoR
APASM_4348	ENOG4105C84	Histidine ammonia-lyase
APASM_4350	ENOG4105CEY	Amp-dependent synthetase and ligase
APASM_4356	ENOG4107EEY	synthase
APASM_4360	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
APASM_4362	ENOG4105EA8	2-Nitropropane dioxygenase
APASM_4363	ENOG4105C1G	acyl-Coa dehydrogenase
APASM_4366	ENOG4105CHU	acetyl-coa acetyltransferase
APASM_4367	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
APASM_4368	ENOG4108IG5	Transcriptional regulator
APASM_4371	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
APASM_4372	ENOG4108XHQ	(2Fe-2S)-binding domain protein
APASM_4374	ENOG4107QRT	dEAD DEAH box helicase
APASM_4378	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
APASM_4380	ENOG4105EAH	synthase
APASM_4381	ENOG4105DB3	bacteriochlorophyll chlorophyll a synthase
APASM_4382	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
APASM_4384	ENOG4105E2B	Taurine dioxygenase
APASM_4387	ENOG4105CIH	Imidazole acetol-phosphate transaminase
APASM_4394	ENOG4108WUH	Transcriptional regulator, TetR family
APASM_4397	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
APASM_4398	ENOG4108IND	Tetr family transcriptional regulator
APASM_4399	ENOG4105W1Y	Transcriptional regulator
APASM_4403	ENOG4108KDT	Molybdate metabolism regulator
APASM_4406	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
APASM_4413	ENOG41068HZ	50S ribosomal protein L32
APASM_4414	ENOG4105NRA	50s ribosomal protein l31 type b
APASM_4416	ENOG4105CH6	catalase
APASM_4417	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
APASM_4418	ENOG4108RPX	mosc domain containing protein
APASM_4422	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
APASM_4424	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
APASM_4432	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_4433	ENOG4105BZU	Histidine kinase
APASM_4437	ENOG4105DIK	(ABC) transporter
APASM_4438	ENOG4105DSE	periplasmic solute binding protein
APASM_4448	ENOG4105C8Y	Acetylornithine aminotransferase
APASM_4459	ENOG4105EJ9	Membrane
APASM_4462	ENOG4105PDP	Short chain dehydrogenase
APASM_4471	ENOG4108IQE	Amp-dependent synthetase and ligase
APASM_4474	ENOG4105KBX	Transcriptional regulator, TetR family
APASM_4475	ENOG4108TKH	Nitroreductase
APASM_4479	ENOG4105D9P	serine threonine protein kinase
APASM_4482	ENOG4105CPQ	Dehydrogenase
APASM_4488	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
APASM_4490	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
APASM_4499	ENOG4105JZC	GHMP kinase
APASM_4502	ENOG4105C5W	Aldolase
APASM_4503	ENOG410880H	cysteine synthase
APASM_4504	ENOG4105CH7	arginosuccinase
APASM_4511	ENOG4105EEM	helicase
APASM_4512	ENOG4105EYF	MMPL domain protein
APASM_4514	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_4515	ENOG4106F60	Histidine kinase
APASM_4516	ENOG4105F44	Two component transcriptional regulator, winged helix family
APASM_4517	ENOG4106T9R	serine protease
APASM_4537	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
APASM_4550	ENOG4105MP0	transposase
APASM_4567	ENOG4108M8W	Monooxygenase
APASM_4569	ENOG4106A3M	Cytochrome p-450
APASM_4571	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
APASM_4575	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
APASM_4583	ENOG4105VEQ	Cold shock protein
APASM_4599	ENOG4105KNA	-acetyltransferase
APASM_4612	ENOG41068W2	Cytochrome p-450
APASM_4616	ENOG4105E1F	short-chain dehydrogenase reductase
APASM_4621	ENOG4105EBR	Carboxylesterase
APASM_4623	ENOG4105DDV	Transcriptional regulator (LacI family
APASM_4627	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
APASM_4634	ENOG4105CHR	reductase
APASM_4635	ENOG41060BG	Tetr family transcriptional regulator
APASM_4637	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
APASM_4639	ENOG4108Z6Z	Transcriptional regulator
APASM_4643	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
APASM_4646	ENOG4105DND	Transcriptional regulator
APASM_4647	ENOG4105C7B	Threonine dehydratase
APASM_4648	ENOG4105CNT	hydrolase family 2
APASM_4650	ENOG41061ZR	Transcriptional regulator
APASM_4656	ENOG4105E2K	Glycosyl transferase (Group 1
APASM_4669	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
APASM_4673	ENOG4105CHR	reductase
APASM_4717	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
APASM_4723	ENOG4107TDE	lipolytic protein G-D-S-L family
APASM_4730	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
APASM_4743	ENOG4108W9Q	Endoglucanase (EC 3.2.1.4)
APASM_4744	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
APASM_4746	ENOG4105C26	Dehydrogenase
APASM_4754	ENOG4105F0K	SARP family transcriptional regulator
APASM_4763	ENOG4107S9F	NmrA family
APASM_4766	ENOG4105KVH	Transcriptional regulator
APASM_4777	ENOG4105C3U	ABC transporter
APASM_4780	ENOG4105DEF	Extracellular solute-binding protein, family 5
APASM_4781	ENOG4105DRR	Transcriptional regulator, GntR family
APASM_4783	ENOG4105CTU	Proline racemase
APASM_4784	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
APASM_4788	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
APASM_4790	ENOG4105ETE	Transcriptional regulator (LacI family
APASM_4792	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
APASM_4799	ENOG4105DA5	(ABC) transporter
APASM_4804	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
APASM_4805	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
APASM_4806	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
APASM_4809	ENOG4105CEI	nitrite reductase
APASM_4823	ENOG4105CFG	Acts as a chaperone (By similarity)
APASM_4827	ENOG4108SV8	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity (By similarity)
APASM_4834	ENOG4108XAN	ABC transporter
APASM_4837	ENOG4105CC5	ABC transporter
APASM_4839	ENOG4105CKI	cobalamin synthesis protein
APASM_4847	ENOG4105C6T	cysteine synthase
APASM_4849	ENOG4105E0A	ABC, transporter
APASM_4850	ENOG4105EHG	Permease protein
APASM_4853	ENOG4107U32	Beta-lactamase domain protein
APASM_4854	ENOG4108N3W	hemolysin secretion protein
APASM_4856	ENOG4108KB2	LysR family Transcriptional regulator
APASM_4858	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
APASM_4861	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
APASM_4862	ENOG4105CUC	YeeE YedE family protein
APASM_4866	ENOG4105C57	major facilitator superfamily
APASM_4867	ENOG4108R86	Transcriptional regulator
APASM_4877	ENOG4105GWZ	Roadblock lc7 family protein
APASM_4881	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
APASM_4884	ENOG4105BZW	Glycerate kinase
APASM_4894	ENOG41068W2	Cytochrome p-450
APASM_4896	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
APASM_4898	ENOG4107S9F	NmrA family
APASM_4906	ENOG4105CJA	serine threonine protein kinase
APASM_4909	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
APASM_4910	ENOG4105CHR	reductase
APASM_4914	ENOG4105CEY	Amp-dependent synthetase and ligase
APASM_4915	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
APASM_4916	ENOG4105C26	Dehydrogenase
APASM_4918	ENOG4107RCI	amp-dependent synthetase and ligase
APASM_4921	ENOG4105YIP	Tetr family transcriptional regulator
APASM_4928	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
APASM_4935	ENOG4105CSA	Coproporphyrinogen iii oxidase
APASM_4938	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
APASM_4940	ENOG4107258	Transcriptional regulator
APASM_4941	ENOG4108I5U	Uridine phosphorylase
APASM_4942	ENOG4105D7T	ABC transporter
APASM_4943	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
APASM_4945	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
APASM_4949	ENOG4105CD3	dihydroorotase
APASM_4951	ENOG4108W5M	transcriptional regulator
APASM_4952	ENOG4108762	serine threonine protein kinase
APASM_4954	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
APASM_4961	ENOG4105DRR	Transcriptional regulator, GntR family
APASM_4962	ENOG4105E0A	ABC, transporter
APASM_4963	ENOG4105TVJ	transport system, permease
APASM_4964	ENOG4105DQ5	transport system permease protein
APASM_4967	ENOG4105CM2	brancheD-chain amino acid aminotransferase
APASM_4968	ENOG4105DEN	Luciferase family
APASM_4976	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
APASM_4981	ENOG4105M2Z	protein tyrosine serine phosphatase
APASM_4983	ENOG4108VQR	secreted hydrolase
APASM_4990	ENOG4105BZW	Glycerate kinase
APASM_4992	ENOG4106F60	Histidine kinase
APASM_4998	ENOG4107RSM	transcriptional regulator
APASM_5001	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
APASM_5005	ENOG4105CVN	desaturase
APASM_5014	ENOG4105CKK	Glycosyl transferase, family 2
APASM_5017	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
APASM_5028	ENOG41088CC	tellurite resistance protein tehB
APASM_5041	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
APASM_5045	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_5052	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
APASM_5055	ENOG4108XM1	transcriptional regulator AsnC family
APASM_5056	ENOG4105K4I	Scp-like extracellular
APASM_5057	ENOG41065SU	Two-component system sensor kinase
APASM_5062	ENOG4105BZU	Histidine kinase
APASM_5066	ENOG4105ESN	nucleotide-binding protein
APASM_5067	ENOG4105ESN	nucleotide-binding protein
APASM_5075	ENOG4106J7S	Glycosyl transferase, family 2
APASM_5077	ENOG4105DQ4	alcohol dehydrogenase
APASM_5080	ENOG4107ZR7	Membrane
APASM_5082	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
APASM_5083	ENOG4105BZU	Histidine kinase
APASM_5091	ENOG4105EEM	helicase
APASM_5095	ENOG4108IXY	short-chain dehydrogenase reductase
APASM_5097	ENOG4108MR6	WD40-like Beta Propeller Repeat
APASM_5099	ENOG4105EEM	helicase
APASM_5101	ENOG4105E0A	ABC, transporter
APASM_5102	ENOG4105TVJ	transport system, permease
APASM_5103	ENOG4105DQ5	transport system permease protein
APASM_5105	ENOG4105CPQ	Dehydrogenase
APASM_5107	ENOG4105DEI	Mannitol dehydrogenase
APASM_5116	ENOG4105BZ1	(ABC) transporter
APASM_5117	ENOG4105BZ1	(ABC) transporter
APASM_5118	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
APASM_5124	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
APASM_5130	ENOG4107HP6	Transcriptional regulator
APASM_5131	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
APASM_5133	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
APASM_5134	ENOG4105RM9	Protocatechuate 3,4-dioxygenase alpha
APASM_5143	ENOG4105BZU	Histidine kinase
APASM_5144	ENOG41082AN	stage II sporulation protein
APASM_5146	ENOG4107R33	ppx gppa phosphatase
APASM_5149	ENOG4105XYF	acetyltransferase
APASM_5153	ENOG41060NJ	transcriptional regulator
APASM_5154	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
APASM_5155	ENOG4108IXY	short-chain dehydrogenase reductase
APASM_5156	ENOG4108Q5F	Tetr family transcriptional regulator
APASM_5167	ENOG4105ETE	Transcriptional regulator (LacI family
APASM_5170	ENOG4105DR5	peptidase
APASM_5171	ENOG4105BZ4	penicillin-binding protein
APASM_5172	ENOG4107UEK	pfkb domain protein
APASM_5174	ENOG4105D74	hydrolase
APASM_5176	ENOG4107RSM	transcriptional regulator
APASM_5177	ENOG4105CHR	reductase
APASM_5178	ENOG410804X	Transcriptional regulator
APASM_5179	ENOG4108SU4	UPF0309 protein
APASM_5180	ENOG4105BZ1	(ABC) transporter
APASM_5182	ENOG4106YT9	Enoyl-CoA hydratase
APASM_5184	ENOG4105C5H	ABC transporter
APASM_5185	ENOG4105CHR	reductase
APASM_5191	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
APASM_5194	ENOG4106TD9	Diguanylate cyclase
APASM_5195	ENOG4106PVI	ATP-dependent carboxylate-amine ligase (By similarity)
APASM_5197	ENOG4105VG1	fes assembly suf system protein
APASM_5198	ENOG4108UNV	SUF system FeS assembly protein, NifU family
APASM_5200	ENOG4105C3K	feS assembly ATPase SufC
APASM_5207	ENOG4107JC6	Membrane
APASM_5211	ENOG4105CJ1	ABC, transporter
APASM_5220	ENOG4105GWZ	Roadblock lc7 family protein
APASM_5223	ENOG4107QN1	sodium solute
APASM_5227	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
APASM_5234	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
APASM_5236	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
APASM_5237	ENOG4105C89	phosphohexose isomerase
APASM_5240	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
APASM_5241	ENOG4105BZU	Histidine kinase
APASM_5246	ENOG4105CP7	Triose-phosphate isomerase
APASM_5247	ENOG4105BZA	Phosphoglycerate kinase
APASM_5248	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
APASM_5252	ENOG4105CIE	May be required for sporulation (By similarity)
APASM_5254	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
APASM_5255	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
APASM_5264	ENOG4105IIU	Aminopeptidase
APASM_5266	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
APASM_5267	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
APASM_5274	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
APASM_5275	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
APASM_5282	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
APASM_5285	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
APASM_5287	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
APASM_5288	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
APASM_5290	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
APASM_5292	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
APASM_5295	ENOG4105CXT	aspartate transcarbamylase
APASM_5296	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
APASM_5298	ENOG410803B	Involved in the transcription termination process (By similarity)
APASM_5299	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
APASM_5300	ENOG4105DC7	peptidase M24
APASM_5303	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
APASM_5304	ENOG4105D49	3-dehydroquinate synthase
APASM_5306	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
APASM_5307	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
APASM_5309	ENOG4105C5Y	PTS System
APASM_5310	ENOG4105CI1	PTS System
APASM_5311	ENOG4105FDP	GntR family transcriptional regulator
APASM_5313	ENOG410849S	phosphocarrier protein (HPr)
APASM_5314	ENOG4105E2X	shikimate dehydrogenase
APASM_5316	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
APASM_5317	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
APASM_5326	ENOG4105CQR	helicase
APASM_5329	ENOG4105DY9	regulatoR
APASM_5332	ENOG4108HRK	Histidine kinase
APASM_5342	ENOG4105KVH	Transcriptional regulator
APASM_5346	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
APASM_5349	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
APASM_5350	ENOG4105E7U	AraC family transcriptional regulator
APASM_5358	ENOG4105CPQ	Dehydrogenase
APASM_5368	ENOG4108RPX	mosc domain containing protein
APASM_5369	ENOG4107S5I	aldo keto reductase
APASM_5372	ENOG4105DXM	phenylacetic acid degradation protein
APASM_5377	ENOG4105EXC	Acyl-transferase
APASM_5380	ENOG4105BZ1	(ABC) transporter
APASM_5385	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
APASM_5386	ENOG4105D3G	Pseudouridine synthase
APASM_5396	ENOG41060NJ	transcriptional regulator
APASM_5401	ENOG4105D9P	serine threonine protein kinase
APASM_5405	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
APASM_5409	ENOG4108UW8	fha domain-containing protein
APASM_5410	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
APASM_5414	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
APASM_5415	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
APASM_5417	ENOG4105KIU	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
APASM_5420	ENOG4105CPC	Aldo Keto reductase
APASM_5430	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_5431	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_5448	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
APASM_5457	ENOG4106PVI	ATP-dependent carboxylate-amine ligase (By similarity)
APASM_5458	ENOG41083UI	stage II sporulation protein
APASM_5462	ENOG4105ECQ	AraC Family Transcriptional Regulator
APASM_5470	ENOG4105BZU	Histidine kinase
APASM_5472	ENOG4105GWZ	Roadblock lc7 family protein
APASM_5474	ENOG4105D2X	ABC transporter substrate-binding protein
APASM_5475	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
APASM_5476	ENOG4105D7T	ABC transporter
APASM_5477	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
APASM_5480	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
APASM_5481	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
APASM_5484	ENOG4105YVS	arsR family transcriptional regulator
APASM_5489	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
APASM_5494	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
APASM_5497	ENOG4105DSU	hydrolase
APASM_5499	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
APASM_5502	ENOG4108VX5	3-methyladenine DNA glycosylase
APASM_5503	ENOG4105CH7	arginosuccinase
APASM_5504	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
APASM_5505	ENOG4105DBV	ornithine carbamoyltransferase
APASM_5507	ENOG4105CAS	nag kinase
APASM_5508	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
APASM_5509	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
APASM_5510	ENOG4105CB2	alcohol dehydrogenase
APASM_5511	ENOG4105VZ8	Transcriptional regulator
APASM_5515	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
APASM_5516	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
APASM_5517	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
APASM_5519	ENOG4105ETX	regulatoR
APASM_5520	ENOG4105GR3	Histidine kinase
APASM_5521	ENOG4108RWN	rrna methyltransferase
APASM_5522	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
APASM_5523	ENOG41084BS	50S ribosomal protein L35
APASM_5524	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
APASM_5534	ENOG4105C6Z	Gluconate
APASM_5538	ENOG4105C5X	domain protein
APASM_5543	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
APASM_5544	ENOG41082BM	Transcriptional regulator, arsr family
APASM_5555	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
APASM_5559	ENOG4108VJY	integral membrane protein
APASM_5564	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
APASM_5566	ENOG4105CJ1	ABC, transporter
APASM_5572	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
APASM_5574	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
APASM_5578	ENOG4105ECB	domain protein
APASM_5582	ENOG4105DDC	Oxidoreductase domain protein
APASM_5584	ENOG4108TZA	Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity)
APASM_5586	ENOG4108IV0	ABC, transporter
APASM_5587	ENOG4105C0Z	ABC transporter
APASM_5588	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
APASM_5589	ENOG4105C32	Amino acid ABC transporter (Permease)
APASM_5595	ENOG4105K4P	CoA-binding domain protein
APASM_5596	ENOG4108176	endoribonuclease L-psp
APASM_5599	ENOG4105DDN	Pentapeptide repeat-containing protein
APASM_5600	ENOG4105C9U	ATP-dependent DNA helicase RecQ
APASM_5604	ENOG4105VPX	protein, conserved in bacteria
APASM_5608	ENOG4105NAF	rna polymerase sigma factor
APASM_5609	ENOG4107RN3	metallophosphoesterase
APASM_5612	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
APASM_5613	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
APASM_5614	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
APASM_5616	ENOG4105XM7	Lipoprotein lprD
APASM_5620	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
APASM_5621	ENOG4105C1G	acyl-Coa dehydrogenase
APASM_5623	ENOG4105CHU	acetyl-coa acetyltransferase
APASM_5624	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
APASM_5629	ENOG4105ETE	Transcriptional regulator (LacI family
APASM_5630	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
APASM_5637	ENOG4107B2H	carbonic anhydrase
APASM_5638	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
APASM_5640	ENOG4105C29	acyl-CoA thioesterase
APASM_5648	ENOG4105CBC	glutamate synthase
APASM_5650	ENOG4105CK2	sodium dicarboxylate symporter
APASM_5652	ENOG41062D9	Histidine kinase
APASM_5654	ENOG4108PYU	two-component system response regulator
APASM_5655	ENOG4107V6M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
APASM_5656	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
APASM_5657	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
APASM_5658	ENOG4105DK0	Indole-3-glycerol phosphate synthase
APASM_5661	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
APASM_5662	ENOG41086VY	Fic/DOC family
APASM_5665	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
APASM_5666	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
APASM_5670	ENOG4108Z4X	TRANSCRIPTIONal
APASM_5671	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
APASM_5673	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
APASM_5674	ENOG4105CIH	Imidazole acetol-phosphate transaminase
APASM_5675	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
APASM_5678	ENOG4105C9B	Cysteine desulfurase
APASM_5683	ENOG4108IYU	L-aspartate oxidase
APASM_5684	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
APASM_5689	ENOG4107RGD	Major Facilitator superfamily
APASM_5690	ENOG4105CFM	UPF0317 protein
APASM_5693	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
APASM_5694	ENOG4107WHG	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
APASM_5697	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
APASM_5701	ENOG4105C2C	drug resistance transporter, Bcr CflA
APASM_5705	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
APASM_5708	ENOG4105VZ9	UPF0235 protein
APASM_5709	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
APASM_5713	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
APASM_5717	ENOG4105ME9	cell division protein FtsQ
APASM_5718	ENOG4105DFU	Cell wall formation (By similarity)
APASM_5725	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
APASM_5726	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
APASM_5729	ENOG4105CJN	penicillin-binding protein
APASM_5732	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
APASM_5733	ENOG4108V6E	Cell division protein mraZ
APASM_5734	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
APASM_5739	ENOG4105IJJ	transcriptional regulator, crp fnr family
APASM_5740	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
APASM_5742	ENOG4105C5F	glutamine synthetase
APASM_5745	ENOG4107QJE	Chromosome Partitioning Protein
APASM_5746	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
APASM_5747	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
APASM_5749	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
APASM_5750	ENOG4105C2W	permease
APASM_5753	ENOG4105WBV	Transcriptional regulator
APASM_5754	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
APASM_5760	ENOG4105CN5	Metallo-Beta-Lactamase
APASM_5761	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
APASM_5768	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
APASM_5770	ENOG4108FN7	Aldo keto reductase
APASM_5771	ENOG4105T0Z	Conserved Protein
APASM_5775	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
APASM_5776	ENOG4105C1V	Peptidase, M16
APASM_5777	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
APASM_5778	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
APASM_5783	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
APASM_5786	ENOG4105SFS	phosphoesterase RecJ domain protein
APASM_5787	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
APASM_5789	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
APASM_5792	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
APASM_5802	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
APASM_5804	ENOG4107XFJ	UPF0246 protein
APASM_5805	ENOG4105EYW	Ion transport protein
APASM_5809	ENOG4105C1J	atp-dependent rna helicase
APASM_5810	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
APASM_5811	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
APASM_5814	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
APASM_5821	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
APASM_5823	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
APASM_5824	ENOG410829K	Lysine exporter protein (Lyse ygga)
APASM_5825	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
APASM_5826	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
APASM_5827	ENOG4105D0M	Protease HtpX homolog
APASM_5829	ENOG4105EQK	-acetyltransferase
APASM_5830	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
APASM_5832	ENOG4108SKZ	Patatin-like phospholipase
APASM_5834	ENOG4108V1U	phospholipid-binding protein
APASM_5836	ENOG4105DJ2	Major Facilitator Superfamily
APASM_5838	ENOG4108594	Permease of the drug metabolite transporter
APASM_5839	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
APASM_5844	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
APASM_5845	ENOG4105DZP	Membrane-associated zinc metalloprotease
APASM_5847	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_5848	ENOG4105BZU	Histidine kinase
APASM_5849	ENOG4105D38	putrescine abc transporter
APASM_5850	ENOG4105F38	ABC transporter, permease
APASM_5852	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
APASM_5854	ENOG4108DT4	serine threonine protein kinase
APASM_5856	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
APASM_5858	ENOG4107SET	aldo keto reductase
APASM_5862	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
APASM_5863	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
APASM_5864	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
APASM_5865	ENOG4105CE9	30S ribosomal protein S2
APASM_5866	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APASM_5867	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
APASM_5869	ENOG4105C0P	Mg chelatase subunit ChlI
APASM_5870	ENOG41080R2	UPF0102 protein
APASM_5872	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
APASM_5873	ENOG4107QYR	Signal peptidase i
APASM_5874	ENOG4107QYR	Signal peptidase i
APASM_5875	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
APASM_5876	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
APASM_5877	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
APASM_5879	ENOG4105K5M	30s ribosomal protein S16
APASM_5880	ENOG4105E7W	lamb ycsf family protein
APASM_5885	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
APASM_5895	ENOG4107R9S	Malate synthase
APASM_5896	ENOG4108FUF	Transcriptional regulator, IclR family
APASM_5899	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
APASM_5901	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
APASM_5908	ENOG4108375	Acylphosphatase (EC 3.6.1.7)
APASM_5909	ENOG4105K4I	Scp-like extracellular
APASM_5915	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
APASM_5917	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
APASM_5918	ENOG41084BZ	50S ribosomal protein L32
APASM_5921	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
APASM_5922	ENOG4106H78	methyltransferase
APASM_5926	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
APASM_5929	ENOG4105CB5	ATP-dependent DNA helicase recG
APASM_5930	ENOG4105DP4	dak2 domain fusion protein ylov
APASM_5931	ENOG4105VB9	50S ribosomal protein l28
APASM_5935	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
APASM_5936	ENOG4108Z0R	Transferase
APASM_5941	ENOG4105CPF	Cell wall formation (By similarity)
APASM_5944	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
APASM_5952	ENOG4105C28	cystathionine
APASM_5953	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
APASM_5955	ENOG4105ME0	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor (By similarity)
APASM_5961	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
APASM_5962	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
APASM_5965	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
APASM_5967	ENOG4105ERH	Fumarylacetoacetate hydrolase
APASM_5969	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
APASM_5970	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
APASM_5971	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
APASM_5975	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
APASM_5976	ENOG4108ZP8	Acetolactate synthase small subunit
APASM_5981	ENOG4105C01	Dihydroxy-acid dehydratase
APASM_5982	ENOG4108VGI	doxx family
APASM_5989	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
APASM_5991	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
APASM_5992	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
APASM_5995	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
APASM_5998	ENOG4107ZR7	Membrane
APASM_6002	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
APASM_6005	ENOG4108Z20	Acyl-transferase
APASM_6007	ENOG4105C10	Electron transfer flavoprotein
APASM_6009	ENOG4105EPR	degv family
APASM_6014	ENOG4108KQJ	Type 11 methyltransferase
APASM_6019	ENOG4105EVB	acetyltransferase
APASM_6022	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
APASM_6023	ENOG4105UPE	Enoyl-CoA hydratase
APASM_6024	ENOG4105DKW	ABC transporter
APASM_6029	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
APASM_6031	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
APASM_6032	ENOG4105CG3	alpha amylase, catalytic region
APASM_6034	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
APASM_6035	ENOG4105CGZ	zinc metallopeptidase
APASM_6041	ENOG41067TZ	transcriptional regulator, MarR family
APASM_6043	ENOG4105EYF	MMPL domain protein
APASM_6048	ENOG41060NJ	transcriptional regulator
APASM_6050	ENOG4105C2J	ABC transporter
APASM_6052	ENOG4106JDR	secreted
APASM_6060	ENOG4105CHU	acetyl-coa acetyltransferase
APASM_6070	ENOG4105CMT	Dihydroxyacetone kinase
APASM_6080	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
APASM_6083	ENOG4105CGU	Enoyl-CoA hydratase
APASM_6087	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
APASM_6090	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
APASM_6091	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
APASM_6092	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
APASM_6093	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
APASM_6094	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
APASM_6095	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
APASM_6096	ENOG4105ZA1	atp synthase
APASM_6097	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
APASM_6099	ENOG4105ESV	Glycosyl transferase, family 4
APASM_6101	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
APASM_6105	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
APASM_6106	ENOG4105VFB	Binds the 23S rRNA (By similarity)
APASM_6108	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
APASM_6109	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
APASM_6110	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
APASM_6111	ENOG4105D6E	homoserine dehydrogenase
APASM_6112	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
APASM_6113	ENOG4105C75	arginyL-tRNA synthetase
APASM_6114	ENOG4105CWX	Alpha-1,2-mannosidase
APASM_6125	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
APASM_6128	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
APASM_6136	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
APASM_6139	ENOG4105CPC	Aldo Keto reductase
APASM_6140	ENOG41060NJ	transcriptional regulator
APASM_6150	ENOG4108HIY	periplasmic
APASM_6154	ENOG4105CPU	Monooxygenase
APASM_6156	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
APASM_6158	ENOG4105CHP	RNA polymerase
APASM_6159	ENOG4105GRZ	Ycii-related protein
APASM_6165	ENOG4108ZHR	arsR family transcriptional regulator
APASM_6167	ENOG4105E2R	ROK family
APASM_6170	ENOG4105C7H	Helicase, RecD TraA family
APASM_6171	ENOG4108PYU	two-component system response regulator
APASM_6172	ENOG4105EB3	Histidine kinase
APASM_6180	ENOG4106NZI	LysR family Transcriptional regulator
APASM_6188	ENOG4105BZU	Histidine kinase
APASM_6189	ENOG4105C0H	protease
APASM_6190	ENOG4105CSU	acyl-Coa dehydrogenase
APASM_6191	ENOG4105E39	Enoyl-CoA hydratase
APASM_6193	ENOG4105C1G	acyl-Coa dehydrogenase
APASM_6195	ENOG4107QX3	carboxylase
APASM_6203	ENOG4106UDK	Cellulose-binding, family II
APASM_6204	ENOG4105DWV	Homoserine O-trans-acetylase
APASM_6206	ENOG4105D9R	oxidoreductase
APASM_6210	ENOG4108V06	Glutathione peroxidase
APASM_6211	ENOG4105EJQ	L-serine dehydratase
APASM_6212	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
APASM_6213	ENOG4105DCF	alanine dehydrogenase
APASM_6217	ENOG4105BZ1	(ABC) transporter
APASM_6218	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
APASM_6221	ENOG4105CPC	Aldo Keto reductase
APASM_6227	ENOG4105CI2	imidazolone-5-propionate hydrolase
APASM_6229	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
APASM_6230	ENOG4105CGP	Urocanate hydratase
APASM_6231	ENOG4105C84	Histidine ammonia-lyase
APASM_6234	ENOG4108U0I	binding-protein-dependent transport systems inner membrane Component
APASM_6235	ENOG4105R40	Glycine betaine carnitine choline
APASM_6236	ENOG4108IJ8	ABC transporter
APASM_6246	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
APASM_6248	ENOG4108VEQ	Superoxide dismutase
APASM_6251	ENOG4108ZM9	phosphoglycerate mutase
APASM_6255	ENOG4105CBD	Diacylglycerol kinase
APASM_6258	ENOG4105WMN	AntiSigma factor
APASM_6259	ENOG4105EMN	RNA polymerase sigma factor
APASM_6260	ENOG4108Z66	YbaK ebsC protein
APASM_6262	ENOG4108RAV	Conserved protein
APASM_6263	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
APASM_6264	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
APASM_6269	ENOG4105C2N	RNA methyltransferase TrmH family group 3
APASM_6270	ENOG4107YBY	Hydrolase
APASM_6272	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
APASM_6273	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
APASM_6274	ENOG4107YHC	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
APASM_6275	ENOG4108T3R	lipoprotein lpqB
APASM_6276	ENOG4105BZU	Histidine kinase
APASM_6277	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
APASM_6281	ENOG4105CUB	amino acid
APASM_6283	ENOG4105EIP	mannose-6-phosphate isomerase
APASM_6291	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
APASM_6292	ENOG4107XZ0	Peptidase M50
APASM_6293	ENOG4105EIH	LPPG Fo 2-phospho-L-lactate transferase
APASM_6294	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
APASM_6301	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
APASM_6305	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
APASM_6306	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
APASM_6308	ENOG4107TB5	TRANSCRIPTIONal
APASM_6309	ENOG4107TB5	TRANSCRIPTIONal
APASM_6311	ENOG4105NQG	DoxX
APASM_6316	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
APASM_6321	ENOG4108IJ6	ABC transporter
APASM_6322	ENOG4105JXH	GntR family transcriptional regulator
APASM_6330	ENOG4107TK4	histidinol-phosphate phosphatase
APASM_6331	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
APASM_6332	ENOG41065SU	Two-component system sensor kinase
APASM_6336	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
APASM_6339	ENOG4105D8K	carboxyl transferase
APASM_6342	ENOG4107WR6	Maf-like protein
APASM_6343	ENOG4107QJT	sodium dicarboxylate symporter
APASM_6345	ENOG4108JIK	carboxylase
APASM_6353	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_6354	ENOG4105BZU	Histidine kinase
APASM_6357	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
APASM_6358	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
APASM_6359	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
APASM_6362	ENOG4107RM1	amidohydrolase
APASM_6371	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
APASM_6375	ENOG41086VY	Fic/DOC family
APASM_6378	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
APASM_6379	ENOG4105CNF	WD-40 repeat protein
APASM_6392	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
APASM_6398	ENOG4105UIB	(ABC) transporter
APASM_6399	ENOG4108JQ9	ABC transporter
APASM_6400	ENOG4105DIH	basic membrane
APASM_6419	ENOG4107H3J	ribonuclease
APASM_6420	ENOG4105C31	Tryptophanyl-tRNA synthetase
APASM_6422	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
APASM_6425	ENOG4105CGK	Exodeoxyribonuclease III
APASM_6431	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
APASM_6436	ENOG4108IUW	ABC transporter
APASM_6441	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
APASM_6446	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
APASM_6450	ENOG4105DC1	bifunctional purine biosynthesis protein purh
APASM_6455	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
APASM_6457	ENOG41061JJ	Peptidase family M23
APASM_6465	ENOG4105D9P	serine threonine protein kinase
APASM_6466	ENOG4107TPY	serine threonine protein kinase
APASM_6467	ENOG4107RSM	transcriptional regulator
APASM_6468	ENOG4105FDR	Membrane
APASM_6469	ENOG4105KF0	sporulation and cell division protein, SsgA
APASM_6474	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
APASM_6479	ENOG4107QVP	Dehydrogenase
APASM_6484	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_6487	ENOG4105KIU	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
APASM_6488	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
APASM_6489	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
APASM_6491	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
APASM_6492	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
APASM_6495	ENOG4105K63	Thioredoxin
APASM_6496	ENOG4105CEY	Amp-dependent synthetase and ligase
APASM_6497	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
APASM_6501	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
APASM_6503	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
APASM_6509	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
APASM_6510	ENOG4108UJD	30S ribosomal protein S9
APASM_6511	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
APASM_6514	ENOG4105CFG	Acts as a chaperone (By similarity)
APASM_6516	ENOG4105EC2	ftsk spoIIIe
APASM_6518	ENOG4108PZM	peptidase S8 and S53, subtilisin, kexin, sedolisin
APASM_6525	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
APASM_6526	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
APASM_6527	ENOG4108ZT0	50S ribosomal protein l17
APASM_6528	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
APASM_6529	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
APASM_6530	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
APASM_6531	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
APASM_6532	ENOG41067V7	50S ribosomal protein L36
APASM_6538	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
APASM_6540	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
APASM_6541	ENOG410849U	50S ribosomal protein L30
APASM_6542	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
APASM_6543	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
APASM_6544	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
APASM_6545	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
APASM_6546	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
APASM_6547	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
APASM_6548	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
APASM_6549	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
APASM_6550	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
APASM_6551	ENOG41082SA	50s ribosomal protein l29
APASM_6552	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
APASM_6553	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
APASM_6554	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
APASM_6555	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
APASM_6556	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
APASM_6557	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
APASM_6558	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
APASM_6559	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
APASM_6561	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
APASM_6562	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
APASM_6563	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
APASM_6564	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
APASM_6572	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
APASM_6573	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
APASM_6582	ENOG41082SK	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
APASM_6583	ENOG4108VZM	50s ribosomal protein L10
APASM_6585	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
APASM_6586	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
APASM_6592	ENOG4108Z7G	MaoC domain protein dehydratase
APASM_6593	ENOG410900P	UPF0336 protein
APASM_6594	ENOG4105WDJ	50S ribosomal protein L33
APASM_6595	ENOG4105BZU	Histidine kinase
APASM_6599	ENOG4108VPT	UPF0234 protein
APASM_6600	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
APASM_6602	ENOG4108M11	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
APASM_6603	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
APASM_6604	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
APASM_6607	ENOG4105CIK	Amidinotransferase
APASM_6608	ENOG4108VVK	transcriptional Regulator, AsnC
APASM_6610	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
APASM_6611	ENOG4105DQU	oxidoreductase, subunit beta
APASM_6615	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
APASM_6618	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
APASM_6619	ENOG4105DF2	NADH dehydrogenase subunit j
APASM_6620	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
APASM_6621	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
APASM_6622	ENOG4108IEH	NADH dehydrogenase subunit g
APASM_6623	ENOG4107QIZ	NADH dehydrogenase
APASM_6625	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
APASM_6626	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
APASM_6627	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
APASM_6630	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
APASM_6634	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
APASM_6635	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
APASM_6636	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
APASM_6637	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
APASM_6638	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
APASM_6640	ENOG4105E4F	Isochorismate synthase
APASM_6641	ENOG41065RQ	ADP-ribosylation crystallin J1
APASM_6648	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
APASM_6658	ENOG4105CRE	cytochrome C
APASM_6659	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
APASM_6660	ENOG4107QIV	Cytochrome c biogenesis protein
APASM_6662	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
APASM_6664	ENOG4108RH7	phosphoglycerate mutase
APASM_6665	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
APASM_6673	ENOG4105D52	delta-aminolevulinic acid dehydratase
APASM_6674	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
APASM_6675	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
APASM_6676	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
APASM_6677	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
APASM_6681	ENOG4105CEY	Amp-dependent synthetase and ligase
APASM_6684	ENOG4108RXW	HAD-superfamily subfamily IB hydrolase
APASM_6689	ENOG4105II7	pyrroline-5-carboxylate reductase
APASM_6695	ENOG4107S5I	aldo keto reductase
APASM_6697	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
APASM_6698	ENOG4105CEY	Amp-dependent synthetase and ligase
APASM_6701	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
APASM_6705	ENOG4107R4N	Cell wall formation (By similarity)
APASM_6711	ENOG4105W1N	transcriptional regulator
APASM_6713	ENOG4107TXC	Transcriptional regulator
APASM_6714	ENOG4108Z0Z	intracellular protease Pfpi family
APASM_6717	ENOG4105V9F	hemagglutinin
APASM_6719	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
APASM_6720	ENOG4106BRA	Membrane
APASM_6726	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
APASM_6733	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
APASM_6734	ENOG4108VW9	Membrane
APASM_6744	ENOG4105VEQ	Cold shock protein
APASM_6748	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
APASM_6758	ENOG4105BZU	Histidine kinase
APASM_6763	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
APASM_6766	ENOG4107QJG	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
APASM_6770	ENOG4105KHC	sulfurtransferase
APASM_6771	ENOG4105PKJ	carbohydrate binding
APASM_6772	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
APASM_6773	ENOG4105P4J	Allophanate hydrolase, subunit 1
APASM_6777	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
APASM_6784	ENOG4105DH8	myo-inositol catabolism
APASM_6786	ENOG4105C2J	ABC transporter
APASM_6787	ENOG41062B0	ABC transporter, permease
APASM_6789	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
APASM_6790	ENOG4106448	streptomycin biosynthesis protein strI
APASM_6791	ENOG4105ETE	Transcriptional regulator (LacI family
APASM_6792	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
APASM_6795	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
APASM_6808	ENOG4105CPQ	Dehydrogenase
APASM_6809	ENOG4105BZU	Histidine kinase
APASM_6814	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
APASM_6815	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
APASM_6816	ENOG410839H	phosphoribosylformylglycinamidine synthase
APASM_6821	ENOG4105C8V	SAICAR synthetase
APASM_6823	ENOG4105E5Q	amino acid AbC transporter
APASM_6826	ENOG4105C83	adenylosuccinate lyase
APASM_6828	ENOG4105JVQ	RNA Polymerase
APASM_6832	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
APASM_6835	ENOG4105CHM	Aminotransferase
APASM_6843	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
APASM_6844	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
APASM_6854	ENOG4105CPC	Aldo Keto reductase
APASM_6855	ENOG4108BAS	reductase
APASM_6857	ENOG4105NAF	rna polymerase sigma factor
APASM_6859	ENOG4105CE4	GlcNAc 6-P deacetylase
APASM_6862	ENOG4105CQB	FAD linked oxidase domain protein
APASM_6863	ENOG4105DQR	SNARE associated Golgi
APASM_6864	ENOG4107Z1W	Fructose transport system kinase
APASM_6870	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
APASM_6875	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
APASM_6877	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
APASM_6879	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
APASM_6880	ENOG4105KNI	merR family transcriptional Regulator
APASM_6881	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
APASM_6882	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
APASM_6883	ENOG4105CFG	Acts as a chaperone (By similarity)
APASM_6889	ENOG4105DF6	Fe-S oxidoreductase
APASM_6890	ENOG41082T9	Membrane
APASM_6895	ENOG4105DHP	deoxycytidine triphosphate deaminase
APASM_6898	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_6899	ENOG4105CSU	acyl-Coa dehydrogenase
APASM_6902	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
APASM_6909	ENOG4105CHR	reductase
APASM_6912	ENOG4105C1G	acyl-Coa dehydrogenase
APASM_6914	ENOG4108R86	Transcriptional regulator
APASM_6915	ENOG4108Z6Z	Transcriptional regulator
APASM_6916	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
APASM_6917	ENOG4105CPP	Dehydrogenase, E1 component
APASM_6919	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
APASM_6921	ENOG4107R0W	ABC transporter
APASM_6922	ENOG4105E5Q	amino acid AbC transporter
APASM_6929	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
APASM_6935	ENOG4105DKQ	ROK family
APASM_6940	ENOG4107Z9D	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
APASM_6943	ENOG4105BZU	Histidine kinase
APASM_6944	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_6945	ENOG4105CHR	reductase
APASM_6949	ENOG4105BZU	Histidine kinase
APASM_6950	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
APASM_6955	ENOG4105CJ1	ABC, transporter
APASM_6958	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
APASM_6963	ENOG4105DXB	Major Facilitator superfamily
APASM_6964	ENOG4107YBY	Hydrolase
APASM_6965	ENOG4108R85	Short chain dehydrogenase
APASM_6969	ENOG4105BZ4	penicillin-binding protein
APASM_6974	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
APASM_6975	ENOG4107YH6	single-stranded DNA-binding protein
APASM_6976	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
APASM_6977	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
APASM_6991	ENOG4105BZU	Histidine kinase
APASM_7000	ENOG4105CGD	Nad-dependent epimerase dehydratase
APASM_7001	ENOG4105CPQ	Dehydrogenase
APASM_7002	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
APASM_7003	ENOG4105DND	Transcriptional regulator
APASM_7007	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
APASM_7008	ENOG4108RVA	ribokinase
APASM_7013	ENOG4105C8T	Leucyl-tRNA synthetase
APASM_7015	ENOG4108UJU	UPF0301 protein
APASM_7017	ENOG4105WH1	Two component transcriptional regulator luxr family
APASM_7018	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
APASM_7025	ENOG4105C3M	thioredoxin reductase
APASM_7026	ENOG4108E1C	hydrolase
APASM_7029	ENOG4105CPF	Cell wall formation (By similarity)
APASM_7031	ENOG4107QJE	Chromosome Partitioning Protein
APASM_7032	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
APASM_7033	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
APASM_7035	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APASM_7036	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
APASM_7037	ENOG4105XH8	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
APASM_7038	ENOG41084CH	50S ribosomal protein l34