locus-tag	class	description
AEQU_0002	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AEQU_0005	COG0706	membrane insertase activity
AEQU_0006	COG1847	R3H domain protein
AEQU_0007	COG0357	Ribosomal RNA small subunit methyltransferase G
AEQU_0008	COG1192	Involved in chromosome partitioning
AEQU_0009	COG1475	DNA binding
AEQU_0010	COG1181	Belongs to the D-alanine--D-alanine ligase family
AEQU_0012	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AEQU_0012	COG1199	ATP-dependent helicase activity
AEQU_0016	COG0629	single-stranded DNA binding
AEQU_0017	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AEQU_0018	COG0359	binds to the 23S rRNA
AEQU_0019	COG0305	Participates in initiation and elongation during chromosome replication
AEQU_0021	COG4717	serine-type aminopeptidase activity
AEQU_0023	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AEQU_0025	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AEQU_0028	COG0622	Phosphoesterase
AEQU_0029	COG3706	GGDEF domain
AEQU_0031	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AEQU_0032	COG0531	amino acid
AEQU_0037	COG1396	sequence-specific DNA binding
AEQU_0039	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AEQU_0041	COG0778	Nitroreductase
AEQU_0043	COG1192	Involved in chromosome partitioning
AEQU_0044	COG1475	DNA binding
AEQU_0048	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AEQU_0051	COG0270	DNA (cytosine-5-)-methyltransferase activity
AEQU_0065	COG4166	transmembrane transport
AEQU_0072	COG3433	isochorismatase activity
AEQU_0072	COG2226	methyltransferase
AEQU_0072	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AEQU_0073	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AEQU_0073	COG2226	methyltransferase
AEQU_0073	COG3433	isochorismatase activity
AEQU_0075	COG1021	2,3-dihydroxybenzoate-AMP ligase
AEQU_0077	COG1132	(ABC) transporter
AEQU_0079	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AEQU_0081	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AEQU_0084	COG2337	Toxic component of a toxin-antitoxin (TA) module
AEQU_0088	COG1012	belongs to the aldehyde dehydrogenase family
AEQU_0089	COG1028	Short-chain dehydrogenase reductase Sdr
AEQU_0090	COG0546	phosphoglycolate phosphatase activity
AEQU_0092	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AEQU_0098	COG0864	Transcriptional regulator
AEQU_0105	COG0443	Heat shock 70 kDa protein
AEQU_0106	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AEQU_0107	COG0484	heat shock protein binding
AEQU_0108	COG0789	Transcriptional regulator
AEQU_0109	COG0542	response to heat
AEQU_0111	COG0393	Putative heavy-metal-binding
AEQU_0113	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AEQU_0114	COG3279	Response regulator of the LytR AlgR family
AEQU_0115	COG0166	Belongs to the GPI family
AEQU_0116	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AEQU_0117	COG0298	carbon dioxide binding
AEQU_0123	COG1610	YqeY-like protein
AEQU_0124	COG0577	efflux transmembrane transporter activity
AEQU_0125	COG1136	(ABC) transporter
AEQU_0126	COG2205	protein histidine kinase activity
AEQU_0131	COG3428	Bacterial PH domain
AEQU_0132	COG4535	Mg2 and Co2 transporter CorC
AEQU_0134	COG0569	domain protein
AEQU_0135	COG0569	domain protein
AEQU_0138	COG1115	amino acid carrier protein
AEQU_0139	COG1763	Mo-molybdopterin cofactor biosynthetic process
AEQU_0142	COG0765	amino acid transport
AEQU_0144	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AEQU_0145	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AEQU_0146	COG3655	Transcriptional regulator
AEQU_0151	COG0528	UMP kinase activity
AEQU_0152	COG0233	cytoplasmic translational termination
AEQU_0154	COG4589	Belongs to the CDS family
AEQU_0155	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AEQU_0157	COG0750	zinc metalloprotease
AEQU_0158	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AEQU_0159	COG0442	prolyl-tRNA aminoacylation
AEQU_0162	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AEQU_0164	COG3620	sequence-specific DNA binding
AEQU_0169	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AEQU_0170	COG2197	response regulator
AEQU_0175	COG0542	response to heat
AEQU_0182	COG0745	RESPONSE REGULATOR receiver
AEQU_0183	COG5002	protein histidine kinase activity
AEQU_0185	COG0437	4 iron, 4 sulfur cluster binding
AEQU_0187	COG1136	(ABC) transporter
AEQU_0193	COG0243	molybdopterin cofactor binding
AEQU_0194	COG0437	4 iron, 4 sulfur cluster binding
AEQU_0195	COG0437	4 iron, 4 sulfur cluster binding
AEQU_0196	COG3381	protein complex oligomerization
AEQU_0199	COG1053	succinate dehydrogenase
AEQU_0199	COG3976	FMN-binding domain protein
AEQU_0205	COG1410	methionine synthase
AEQU_0205	COG0646	methionine synthase
AEQU_0208	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AEQU_0209	COG0402	S-adenosylhomocysteine deaminase activity
AEQU_0211	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AEQU_0212	COG0085	RNA polymerase activity
AEQU_0213	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AEQU_0214	COG0583	DNA-binding transcription factor activity
AEQU_0220	COG0243	molybdopterin cofactor binding
AEQU_0221	COG0437	4 iron, 4 sulfur cluster binding
AEQU_0226	COG0140	phosphoribosyl-ATP diphosphatase activity
AEQU_0227	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AEQU_0230	COG0733	neurotransmitter:sodium symporter activity
AEQU_0233	COG2076	Multidrug Resistance protein
AEQU_0237	COG0243	molybdopterin cofactor binding
AEQU_0238	COG0437	4 iron, 4 sulfur cluster binding
AEQU_0248	COG2326	polyphosphate kinase activity
AEQU_0249	COG4509	Sortase family
AEQU_0250	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AEQU_0252	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AEQU_0253	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AEQU_0255	COG0138	bifunctional purine biosynthesis protein purh
AEQU_0260	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AEQU_0262	COG2197	response regulator
AEQU_0263	COG2304	oxidoreductase activity
AEQU_0265	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AEQU_0266	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AEQU_0267	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AEQU_0268	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AEQU_0270	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AEQU_0271	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AEQU_0275	COG2357	RelA SpoT domain protein
AEQU_0278	COG0215	cysteine-tRNA ligase activity
AEQU_0279	COG1053	succinate dehydrogenase
AEQU_0279	COG3976	FMN-binding domain protein
AEQU_0284	COG0545	Peptidyl-prolyl cis-trans isomerase
AEQU_0285	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AEQU_0286	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AEQU_0287	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AEQU_0288	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AEQU_0289	COG0137	argininosuccinate synthase activity
AEQU_0291	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AEQU_0293	COG0826	peptidase U32
AEQU_0294	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AEQU_0300	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AEQU_0302	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AEQU_0303	COG3383	formate dehydrogenase (NAD+) activity
AEQU_0304	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AEQU_0305	COG0651	ATP synthesis coupled electron transport
AEQU_0306	COG0650	Formate hydrogenlyase subunit 4
AEQU_0307	COG4237	Hydrogenase 4 membrane
AEQU_0308	COG0651	ATP synthesis coupled electron transport
AEQU_0309	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AEQU_0309	COG3261	NADH dehydrogenase
AEQU_0310	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AEQU_0311	COG3260	NADH ubiquinone oxidoreductase 20
AEQU_0313	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AEQU_0314	COG2116	formate transmembrane transporter activity
AEQU_0315	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AEQU_0319	COG0586	Pfam SNARE associated Golgi protein
AEQU_0321	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AEQU_0322	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AEQU_0323	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AEQU_0326	COG1288	antiporter activity
AEQU_0334	COG0024	Methionine aminopeptidase
AEQU_0336	COG0697	spore germination
AEQU_0338	COG0477	Major facilitator Superfamily
AEQU_0341	COG0484	heat shock protein binding
AEQU_0347	COG1924	4 iron, 4 sulfur cluster binding
AEQU_0348	COG3381	protein complex oligomerization
AEQU_0350	COG0437	4 iron, 4 sulfur cluster binding
AEQU_0351	COG0437	4 iron, 4 sulfur cluster binding
AEQU_0352	COG0243	molybdopterin cofactor binding
AEQU_0354	COG2814	Major facilitator Superfamily
AEQU_0360	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AEQU_0366	COG3550	peptidyl-serine autophosphorylation
AEQU_0368	COG0326	Molecular chaperone. Has ATPase activity
AEQU_0372	COG3956	TIGRFAM MazG family protein
AEQU_0374	COG1053	succinate dehydrogenase
AEQU_0374	COG3976	FMN-binding domain protein
AEQU_0375	COG1228	amidohydrolase
AEQU_0376	COG2235	arginine
AEQU_0377	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AEQU_0378	COG0549	Belongs to the carbamate kinase family
AEQU_0379	COG1834	amidinotransferase
AEQU_0382	COG0477	Major facilitator Superfamily
AEQU_0384	COG1834	amidinotransferase
AEQU_0385	COG0477	Major facilitator Superfamily
AEQU_0387	COG0436	Aminotransferase
AEQU_0393	COG2414	aldehyde ferredoxin oxidoreductase
AEQU_0394	COG0437	4 iron, 4 sulfur cluster binding
AEQU_0396	COG0437	4 iron, 4 sulfur cluster binding
AEQU_0398	COG1876	peptidase activity
AEQU_0402	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AEQU_0403	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AEQU_0407	COG0482	sulfurtransferase activity
AEQU_0409	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AEQU_0410	COG0784	Response regulator, receiver
AEQU_0410	COG2205	protein histidine kinase activity
AEQU_0416	COG0437	4 iron, 4 sulfur cluster binding
AEQU_0417	COG0542	response to heat
AEQU_0421	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AEQU_0435	COG0560	Phosphoserine phosphatase
AEQU_0439	COG2843	Capsule synthesis protein
AEQU_0440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AEQU_0442	COG0604	alcohol dehydrogenase
AEQU_0442	COG1028	Short-chain dehydrogenase reductase Sdr
AEQU_0442	COG3321	synthase
AEQU_0446	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AEQU_0446	COG0825	malonyl-CoA metabolic process
AEQU_0451	COG1131	(ABC) transporter
AEQU_0455	COG0515	serine threonine protein kinase
AEQU_0455	COG2815	serine threonine protein kinase
AEQU_0459	COG1968	undecaprenyl-diphosphatase activity
AEQU_0461	COG1725	Transcriptional regulator
AEQU_0465	COG3550	peptidyl-serine autophosphorylation
AEQU_0468	COG0243	molybdopterin cofactor binding
AEQU_0469	COG0437	4 iron, 4 sulfur cluster binding
AEQU_0475	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AEQU_0479	COG3845	ABC transporter
AEQU_0480	COG1122	ATPase activity
AEQU_0481	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AEQU_0484	COG3973	AAA domain
AEQU_0489	COG0789	Transcriptional regulator
AEQU_0492	COG1201	RNA secondary structure unwinding
AEQU_0496	COG0824	Thioesterase
AEQU_0497	COG3254	rhamnose metabolic process
AEQU_0498	COG1396	sequence-specific DNA binding
AEQU_0500	COG1288	antiporter activity
AEQU_0501	COG2235	arginine
AEQU_0502	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AEQU_0509	COG0542	response to heat
AEQU_0513	COG0288	reversible hydration of carbon dioxide
AEQU_0518	COG1725	Transcriptional regulator
AEQU_0519	COG0243	molybdopterin cofactor binding
AEQU_0520	COG0437	4 iron, 4 sulfur cluster binding
AEQU_0524	COG1316	TRANSCRIPTIONal
AEQU_0532	COG0822	iron-sulfur transferase activity
AEQU_0534	COG1959	2 iron, 2 sulfur cluster binding
AEQU_0535	COG0784	Response regulator, receiver
AEQU_0535	COG2205	protein histidine kinase activity
AEQU_0536	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AEQU_0536	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AEQU_0537	COG0084	hydrolase, TatD family'
AEQU_0539	COG3550	peptidyl-serine autophosphorylation
AEQU_0541	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AEQU_0543	COG1247	-acetyltransferase
AEQU_0544	COG0514	ATP-dependent DNA helicase (RecQ)
AEQU_0545	COG0538	isocitrate dehydrogenase activity
AEQU_0548	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AEQU_0549	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AEQU_0550	COG0437	4 iron, 4 sulfur cluster binding
AEQU_0551	COG0243	molybdopterin cofactor binding
AEQU_0554	COG0348	domain, Protein
AEQU_0555	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AEQU_0557	COG1138	Cytochrome C-type biogenesis protein
AEQU_0558	COG4555	ABC transporter
AEQU_0566	COG1053	succinate dehydrogenase
AEQU_0566	COG3976	FMN-binding domain protein
AEQU_0570	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AEQU_0574	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AEQU_0579	COG2184	nucleotidyltransferase activity
AEQU_0580	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AEQU_0584	COG3853	Toxic anion resistance protein (TelA)
AEQU_0588	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AEQU_0590	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AEQU_0591	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AEQU_0592	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AEQU_0593	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AEQU_0594	COG0006	proline dipeptidase activity
AEQU_0596	COG3976	FMN-binding domain protein
AEQU_0596	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AEQU_0597	COG3381	protein complex oligomerization
AEQU_0598	COG0437	4 iron, 4 sulfur cluster binding
AEQU_0599	COG0243	molybdopterin cofactor binding
AEQU_0607	COG0511	ligase activity, forming carbon-carbon bonds
AEQU_0607	COG5016	pyruvate
AEQU_0608	COG0439	Biotin carboxylase
AEQU_0610	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AEQU_0612	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AEQU_0614	COG0004	ammonium transporteR
AEQU_0615	COG0347	Belongs to the P(II) protein family
AEQU_0620	COG0539	negative regulation of cytoplasmic translation
AEQU_0621	COG0237	dephospho-CoA kinase activity
AEQU_0622	COG2197	response regulator
AEQU_0623	COG1053	succinate dehydrogenase
AEQU_0627	COG0556	nucleotide-excision repair
AEQU_0628	COG0726	polysaccharide deacetylase
AEQU_0629	COG0497	DNA recombination
AEQU_0633	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AEQU_0635	COG0072	phenylalanine-tRNA ligase activity
AEQU_0636	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AEQU_0638	COG0736	holo-[acyl-carrier-protein] synthase activity
AEQU_0639	COG2202	Pas domain
AEQU_0639	COG2205	protein histidine kinase activity
AEQU_0642	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AEQU_0644	COG1705	Flagellar rod assembly protein muramidase FlgJ
AEQU_0644	COG3942	CHAP domain
AEQU_0645	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AEQU_0649	COG1134	teichoic acid transport
AEQU_0651	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AEQU_0652	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AEQU_0654	COG1216	Glycosyl transferase, family 2
AEQU_0655	COG1216	Glycosyl transferase, family 2
AEQU_0656	COG1216	Glycosyl transferase, family 2
AEQU_0659	COG0706	membrane insertase activity
AEQU_0670	COG0653	protein targeting
AEQU_0671	COG3328	transposase activity
AEQU_0678	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AEQU_0680	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AEQU_0680	COG1215	transferase activity, transferring glycosyl groups
AEQU_0684	COG1696	Membrane protein involved in D-alanine export
AEQU_0686	COG1088	dTDP-glucose 4,6-dehydratase activity
AEQU_0687	COG1404	Belongs to the peptidase S8 family
AEQU_0690	COG3475	LICD family
AEQU_0694	COG1216	Glycosyl transferase, family 2
AEQU_0696	COG1376	ErfK ybiS ycfS ynhG family protein
AEQU_0699	COG0697	spore germination
AEQU_0700	COG4750	Nucleotidyl transferase
AEQU_0701	COG1773	rubredoxin
AEQU_0701	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AEQU_0702	COG1316	TRANSCRIPTIONal
AEQU_0704	COG0343	queuine tRNA-ribosyltransferase activity
AEQU_0705	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AEQU_0709	COG2197	response regulator
AEQU_0710	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AEQU_0710	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AEQU_0712	COG2197	response regulator
AEQU_0715	COG0535	radical SAM domain protein
AEQU_0717	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AEQU_0718	COG1120	ATPase activity
AEQU_0720	COG1122	ATPase activity
AEQU_0721	COG1122	ATPase activity
AEQU_0722	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AEQU_0724	COG1115	amino acid carrier protein
AEQU_0725	COG1115	amino acid carrier protein
AEQU_0726	COG2081	HI0933 family
AEQU_0727	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AEQU_0729	COG2267	carboxylic ester hydrolase activity
AEQU_0731	COG1401	restriction endodeoxyribonuclease activity
AEQU_0732	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AEQU_0735	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AEQU_0737	COG2131	deaminase
AEQU_0739	COG0356	it plays a direct role in the translocation of protons across the membrane
AEQU_0741	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AEQU_0742	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AEQU_0743	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AEQU_0744	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AEQU_0745	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AEQU_0752	COG0101	tRNA pseudouridine synthase activity
AEQU_0753	COG4656	Part of a membrane complex involved in electron transport
AEQU_0754	COG0733	neurotransmitter:sodium symporter activity
AEQU_0755	COG0012	GTP binding
AEQU_0756	COG3177	Filamentation induced by cAMP protein fic
AEQU_0760	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AEQU_0761	COG0154	amidase activity
AEQU_0762	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AEQU_0766	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AEQU_0769	COG1013	pyruvate-flavodoxin oxidoreductase activity
AEQU_0770	COG0745	RESPONSE REGULATOR receiver
AEQU_0771	COG2202	Pas domain
AEQU_0771	COG2205	protein histidine kinase activity
AEQU_0772	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AEQU_0779	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AEQU_0781	COG2235	arginine
AEQU_0782	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AEQU_0783	COG1288	antiporter activity
AEQU_0784	COG0018	arginyl-trna synthetase
AEQU_0787	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AEQU_0787	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AEQU_0791	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AEQU_0793	COG0025	NhaP-type Na H and K H
AEQU_0794	COG0180	Tryptophanyl-tRNA synthetase
AEQU_0796	COG0494	nUDIX hydrolase
AEQU_0797	COG0488	(ABC) transporter
AEQU_0800	COG0025	NhaP-type Na H and K H
AEQU_0802	COG1053	succinate dehydrogenase
AEQU_0802	COG3976	FMN-binding domain protein
AEQU_0804	COG1994	Peptidase M50
AEQU_0806	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AEQU_0808	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AEQU_0816	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AEQU_0817	COG0204	Acyl-transferase
AEQU_0818	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AEQU_0820	COG1160	GTP binding
AEQU_0822	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AEQU_0826	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AEQU_0827	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AEQU_0828	COG1104	cysteine desulfurase activity
AEQU_0832	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AEQU_0833	COG1302	Protein conserved in bacteria
AEQU_0834	COG1461	Dihydroxyacetone kinase
AEQU_0835	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AEQU_0836	COG0742	ribosomal rna small subunit methyltransferase
AEQU_0839	COG0038	chloride channel
AEQU_0840	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AEQU_0841	COG0416	fatty acid biosynthetic process
AEQU_0842	COG0571	ribonuclease III activity
AEQU_0843	COG1196	nuclear chromosome segregation
AEQU_0845	COG0243	molybdopterin cofactor binding
AEQU_0846	COG0437	4 iron, 4 sulfur cluster binding
AEQU_0851	COG2226	methyltransferase
AEQU_0853	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AEQU_0859	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AEQU_0863	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AEQU_0865	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AEQU_0867	COG0513	Belongs to the DEAD box helicase family
AEQU_0868	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AEQU_0871	COG1597	lipid kinase activity
AEQU_0872	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AEQU_0873	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AEQU_0875	COG0105	UTP biosynthetic process
AEQU_0880	COG1077	Cell shape determining protein MreB Mrl
AEQU_0881	COG1792	Involved in formation and maintenance of cell shape
AEQU_0884	COG0772	Belongs to the SEDS family
AEQU_0888	COG0537	adenosine 5'-monophosphoramidase activity
AEQU_0891	COG1151	hydroxylamine reductase activity
AEQU_0895	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AEQU_0896	COG0792	nuclease activity
AEQU_0898	COG0758	DNA mediated transformation
AEQU_0899	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AEQU_0903	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AEQU_0905	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AEQU_0907	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AEQU_0917	COG1074	ATP-dependent DNA helicase activity
AEQU_0920	COG0583	DNA-binding transcription factor activity
AEQU_0921	COG3976	FMN-binding domain protein
AEQU_0921	COG1053	succinate dehydrogenase
AEQU_0923	COG3976	FMN-binding domain protein
AEQU_0923	COG1053	succinate dehydrogenase
AEQU_0923	COG0431	NADPH-dependent FMN reductase
AEQU_0926	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AEQU_0929	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AEQU_0931	COG0318	PFAM AMP-dependent synthetase and ligase
AEQU_0935	COG1960	acyl-CoA dehydrogenase activity
AEQU_0937	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AEQU_0938	COG2086	electron transfer activity
AEQU_0939	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AEQU_0940	COG2181	nitrate reductase activity
AEQU_0940	COG0247	lactate metabolic process
AEQU_0944	COG0318	PFAM AMP-dependent synthetase and ligase
AEQU_0945	COG0318	PFAM AMP-dependent synthetase and ligase
AEQU_0948	COG1053	succinate dehydrogenase
AEQU_0948	COG3976	FMN-binding domain protein
AEQU_0951	COG0243	molybdopterin cofactor binding
AEQU_0952	COG0437	4 iron, 4 sulfur cluster binding
AEQU_0956	COG0243	molybdopterin cofactor binding
AEQU_0957	COG0437	4 iron, 4 sulfur cluster binding
AEQU_0959	COG1960	acyl-CoA dehydrogenase activity
AEQU_0961	COG0583	DNA-binding transcription factor activity
AEQU_0962	COG0779	Required for maturation of 30S ribosomal subunits
AEQU_0963	COG0195	Participates in both transcription termination and antitermination
AEQU_0965	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AEQU_0965	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AEQU_0966	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AEQU_0967	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AEQU_0968	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AEQU_0969	COG0196	riboflavin kinase activity
AEQU_0970	COG1368	sulfuric ester hydrolase activity
AEQU_0971	COG0322	excinuclease ABC activity
AEQU_0972	COG1660	Displays ATPase and GTPase activities
AEQU_0973	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AEQU_0974	COG1481	regulation of sporulation
AEQU_0976	COG0126	phosphoglycerate kinase activity
AEQU_0977	COG0149	triose-phosphate isomerase activity
AEQU_0978	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AEQU_0979	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AEQU_0982	COG0861	Integral membrane protein TerC family
AEQU_0984	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AEQU_0992	COG1597	lipid kinase activity
AEQU_0993	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AEQU_0994	COG2738	Putative neutral zinc metallopeptidase
AEQU_0995	COG1570	exodeoxyribonuclease VII activity
AEQU_0996	COG1722	exodeoxyribonuclease VII activity
AEQU_0997	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AEQU_0998	COG1053	succinate dehydrogenase
AEQU_0998	COG3976	FMN-binding domain protein
AEQU_1002	COG1215	transferase activity, transferring glycosyl groups
AEQU_1003	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AEQU_1004	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AEQU_1006	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AEQU_1007	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AEQU_1008	COG0564	pseudouridine synthase activity
AEQU_1009	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AEQU_1011	COG1053	succinate dehydrogenase
AEQU_1012	COG0583	DNA-binding transcription factor activity
AEQU_1013	COG1053	succinate dehydrogenase
AEQU_1014	COG1053	succinate dehydrogenase
AEQU_1014	COG3976	FMN-binding domain protein
AEQU_1015	COG2197	response regulator
AEQU_1016	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AEQU_1017	COG1053	succinate dehydrogenase
AEQU_1017	COG3976	FMN-binding domain protein
AEQU_1021	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AEQU_1021	COG2111	Na H antiporter
AEQU_1022	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AEQU_1023	COG3260	NADH ubiquinone oxidoreductase 20
AEQU_1026	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AEQU_1028	COG2720	vancomycin resistance protein
AEQU_1031	COG1686	Belongs to the peptidase S11 family
AEQU_1036	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AEQU_1037	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AEQU_1050	COG0756	dUTP diphosphatase activity
AEQU_1051	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AEQU_1052	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AEQU_1053	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AEQU_1055	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AEQU_1056	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AEQU_1057	COG2359	stage V sporulation protein S
AEQU_1059	COG1418	mRNA catabolic process
AEQU_1062	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AEQU_1063	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AEQU_1064	COG1666	GTP binding
AEQU_1067	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AEQU_1068	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AEQU_1069	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AEQU_1070	COG1185	polyribonucleotide nucleotidyltransferase activity
AEQU_1071	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AEQU_1075	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AEQU_1078	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AEQU_1079	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AEQU_1080	COG1420	regulation of RNA biosynthetic process
AEQU_1081	COG0484	heat shock protein binding
AEQU_1082	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AEQU_1087	COG0481	GTPase activity
AEQU_1088	COG0268	Binds directly to 16S ribosomal RNA
AEQU_1091	COG2333	competence protein COMEC
AEQU_1091	COG0658	competence protein
AEQU_1092	COG1555	photosystem II stabilization
AEQU_1092	COG1596	polysaccharide export
AEQU_1093	COG0301	tRNA thio-modification
AEQU_1095	COG0194	GDP metabolic process
AEQU_1097	COG0284	orotidine-5'-phosphate decarboxylase activity
AEQU_1098	COG0167	dihydroorotate dehydrogenase activity
AEQU_1099	COG0543	2 iron, 2 sulfur cluster binding
AEQU_1100	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AEQU_1101	COG0505	Belongs to the CarA family
AEQU_1102	COG1120	ATPase activity
AEQU_1103	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AEQU_1104	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AEQU_1105	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AEQU_1106	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AEQU_1107	COG0540	Belongs to the ATCase OTCase family
AEQU_1108	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AEQU_1109	COG1592	Rubrerythrin
AEQU_1111	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AEQU_1115	COG1144	Oxidoreductase
AEQU_1116	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AEQU_1116	COG0674	pyruvate-flavodoxin oxidoreductase activity
AEQU_1118	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AEQU_1120	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AEQU_1120	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AEQU_1121	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AEQU_1122	COG0242	peptide deformylase activity
AEQU_1123	COG0358	DNA primase activity
AEQU_1124	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AEQU_1125	COG0328	RNA-DNA hybrid ribonuclease activity
AEQU_1127	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AEQU_1128	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AEQU_1129	COG0440	acetolactate synthase activity
AEQU_1130	COG0028	Belongs to the TPP enzyme family
AEQU_1134	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AEQU_1135	COG2890	protein-(glutamine-N5) methyltransferase activity
AEQU_1136	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AEQU_1139	COG0437	4 iron, 4 sulfur cluster binding
AEQU_1140	COG0243	molybdopterin cofactor binding
AEQU_1142	COG0569	domain protein
AEQU_1142	COG0475	glutathione-regulated potassium exporter activity
AEQU_1144	COG0492	ferredoxin-NADP+ reductase activity
AEQU_1145	COG4145	pantothenate transmembrane transporter activity
AEQU_1147	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AEQU_1150	COG0525	valine-tRNA ligase activity
AEQU_1151	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AEQU_1152	COG0740	serine-type endopeptidase activity
AEQU_1153	COG0544	peptidyl-prolyl cis-trans isomerase activity
AEQU_1160	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AEQU_1161	COG5263	repeat protein
AEQU_1161	COG5632	N-Acetylmuramoyl-L-alanine amidase
AEQU_1181	COG0740	serine-type endopeptidase activity
AEQU_1196	COG0592	DNA-directed DNA polymerase activity
AEQU_1205	COG1396	sequence-specific DNA binding
AEQU_1206	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AEQU_1208	COG0116	Belongs to the methyltransferase superfamily
AEQU_1208	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AEQU_1209	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AEQU_1210	COG0745	RESPONSE REGULATOR receiver
AEQU_1212	COG0437	4 iron, 4 sulfur cluster binding
AEQU_1213	COG0243	molybdopterin cofactor binding
AEQU_1216	COG1053	succinate dehydrogenase
AEQU_1217	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AEQU_1218	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AEQU_1227	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AEQU_1232	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AEQU_1239	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AEQU_1240	COG1605	Chorismate mutase
AEQU_1240	COG0077	Prephenate dehydratase
AEQU_1247	COG1132	(ABC) transporter
AEQU_1250	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AEQU_1253	COG1192	Involved in chromosome partitioning
AEQU_1255	COG0574	Belongs to the PEP-utilizing enzyme family
AEQU_1255	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AEQU_1257	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AEQU_1258	COG0751	glycine-tRNA ligase activity
AEQU_1259	COG0752	glycyl-tRNA synthetase alpha subunit
AEQU_1260	COG0681	Belongs to the peptidase S26 family
AEQU_1261	COG0336	Belongs to the RNA methyltransferase TrmD family
AEQU_1262	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AEQU_1263	COG1837	Belongs to the UPF0109 family
AEQU_1264	COG0228	four-way junction DNA binding
AEQU_1267	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AEQU_1268	COG0601	transmembrane transport
AEQU_1269	COG0747	negative chemotaxis
AEQU_1271	COG0552	protein localization to endoplasmic reticulum
AEQU_1272	COG0733	neurotransmitter:sodium symporter activity
AEQU_1274	COG0437	4 iron, 4 sulfur cluster binding
AEQU_1279	COG0557	exoribonuclease II activity
AEQU_1281	COG2177	Part of the ABC transporter FtsEX involved in
AEQU_1282	COG2884	Cell division ATP-binding protein ftsE
AEQU_1283	COG3958	Transketolase
AEQU_1289	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AEQU_1290	COG0653	protein targeting
AEQU_1293	COG1294	oxidase, subunit
AEQU_1294	COG1271	oxidase subunit
AEQU_1296	COG0799	negative regulation of ribosome biogenesis
AEQU_1297	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AEQU_1297	COG1713	HD superfamily hydrolase involved in NAD metabolism
AEQU_1298	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AEQU_1299	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AEQU_1300	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AEQU_1301	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AEQU_1303	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AEQU_1304	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AEQU_1305	COG1288	antiporter activity
AEQU_1306	COG2235	arginine
AEQU_1308	COG2197	response regulator
AEQU_1309	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AEQU_1309	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AEQU_1310	COG0745	RESPONSE REGULATOR receiver
AEQU_1311	COG0174	glutamine synthetase
AEQU_1313	COG2033	superoxide reductase activity
AEQU_1314	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AEQU_1317	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AEQU_1317	COG0316	Belongs to the HesB IscA family
AEQU_1319	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AEQU_1324	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AEQU_1324	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AEQU_1327	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AEQU_1328	COG0583	DNA-binding transcription factor activity
AEQU_1330	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AEQU_1335	COG0107	imidazoleglycerol-phosphate synthase activity
AEQU_1336	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AEQU_1337	COG0131	Imidazoleglycerol-phosphate dehydratase
AEQU_1338	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AEQU_1339	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AEQU_1340	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AEQU_1341	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AEQU_1342	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
AEQU_1343	COG1691	(AIR) carboxylase
AEQU_1344	COG0789	Transcriptional regulator
AEQU_1346	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AEQU_1350	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AEQU_1351	COG1363	Peptidase, m42
AEQU_1356	COG1307	EDD domain protein, DegV family
AEQU_1359	COG1307	EDD domain protein, DegV family
AEQU_1360	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AEQU_1361	COG1774	PSP1 C-terminal conserved region
AEQU_1363	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AEQU_1364	COG0281	malic enzyme
AEQU_1365	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AEQU_1366	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AEQU_1366	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AEQU_1368	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AEQU_1368	COG0551	DNA topoisomerase type I activity
AEQU_1374	COG0789	Transcriptional regulator
AEQU_1375	COG0765	amino acid transport
AEQU_1376	COG0765	amino acid transport
AEQU_1377	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AEQU_1379	COG3872	metal-dependent enzyme
AEQU_1380	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AEQU_1381	COG2226	methyltransferase
AEQU_1382	COG1278	Cold shock
AEQU_1384	COG2255	four-way junction helicase activity
AEQU_1387	COG1028	Short-chain dehydrogenase reductase Sdr
AEQU_1388	COG0217	transcriptional regulatory protein
AEQU_1389	COG2909	trisaccharide binding
AEQU_1392	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AEQU_1394	COG3976	FMN-binding domain protein
AEQU_1394	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AEQU_1396	COG0437	4 iron, 4 sulfur cluster binding
AEQU_1397	COG0243	molybdopterin cofactor binding
AEQU_1399	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AEQU_1400	COG4149	molybdate abc transporter
AEQU_1403	COG0617	tRNA 3'-terminal CCA addition
AEQU_1407	COG1053	succinate dehydrogenase
AEQU_1407	COG3976	FMN-binding domain protein
AEQU_1408	COG0351	phosphomethylpyrimidine kinase
AEQU_1409	COG1335	isochorismatase
AEQU_1410	COG0352	thiamine-phosphate diphosphorylase activity
AEQU_1411	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AEQU_1414	COG0762	integral membrane protein
AEQU_1415	COG1799	cell septum assembly
AEQU_1418	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AEQU_1419	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AEQU_1420	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AEQU_1421	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AEQU_1422	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AEQU_1423	COG0772	Belongs to the SEDS family
AEQU_1424	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AEQU_1428	COG0768	penicillin binding
AEQU_1430	COG0275	rRNA processing
AEQU_1431	COG2001	Belongs to the MraZ family
AEQU_1432	COG4974	Belongs to the 'phage' integrase family
AEQU_1433	COG0252	asparaginase activity
AEQU_1434	COG2860	membrane
AEQU_1435	COG4868	Belongs to the UPF0371 family
AEQU_1439	COG0504	CTP synthase activity
AEQU_1440	COG0024	Methionine aminopeptidase
AEQU_1441	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AEQU_1443	COG0081	regulation of translation
AEQU_1444	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AEQU_1445	COG0250	Participates in transcription elongation, termination and antitermination
AEQU_1446	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AEQU_1447	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AEQU_1450	COG0426	domain, Protein
AEQU_1451	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AEQU_1452	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AEQU_1454	COG1794	racemase activity, acting on amino acids and derivatives
AEQU_1456	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AEQU_1456	COG3976	FMN-binding domain protein
AEQU_1459	COG1013	pyruvate-flavodoxin oxidoreductase activity
AEQU_1459	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AEQU_1459	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AEQU_1459	COG0674	pyruvate-flavodoxin oxidoreductase activity
AEQU_1460	COG0747	negative chemotaxis
AEQU_1462	COG0563	adenylate kinase activity
AEQU_1464	COG0200	Binds to the 23S rRNA
AEQU_1465	COG1841	ribosomal large subunit assembly
AEQU_1466	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AEQU_1467	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AEQU_1468	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AEQU_1469	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AEQU_1470	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AEQU_1471	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AEQU_1472	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AEQU_1474	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AEQU_1475	COG0255	Belongs to the universal ribosomal protein uL29 family
AEQU_1476	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AEQU_1477	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AEQU_1478	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AEQU_1479	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AEQU_1480	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AEQU_1485	COG0544	peptidyl-prolyl cis-trans isomerase activity
AEQU_1487	COG1136	(ABC) transporter
AEQU_1492	COG2197	response regulator
AEQU_1495	COG0089	rRNA binding
AEQU_1496	COG0088	Forms part of the polypeptide exit tunnel
AEQU_1497	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AEQU_1498	COG0051	transcription antitermination factor activity, RNA binding
AEQU_1499	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AEQU_1500	COG0049	tRNA binding
AEQU_1501	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AEQU_1504	COG1053	succinate dehydrogenase
AEQU_1504	COG3976	FMN-binding domain protein
AEQU_1507	COG2195	Cleaves the N-terminal amino acid of tripeptides
AEQU_1508	COG1227	inorganic diphosphatase activity
AEQU_1509	COG1760	l-serine dehydratase
AEQU_1511	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AEQU_1517	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AEQU_1520	COG2860	membrane
AEQU_1522	COG0306	phosphate transporter
AEQU_1523	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AEQU_1524	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AEQU_1525	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AEQU_1525	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AEQU_1526	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AEQU_1527	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AEQU_1528	COG0602	queuosine metabolic process
AEQU_1529	COG0720	synthase
AEQU_1531	COG1739	Uncharacterized protein family UPF0029
AEQU_1532	COG0488	(ABC) transporter
AEQU_1533	COG2814	Major facilitator Superfamily
AEQU_1534	COG0193	aminoacyl-tRNA hydrolase activity
AEQU_1535	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AEQU_1536	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AEQU_1538	COG2217	Heavy metal translocating P-type atpase
AEQU_1539	COG1937	Protein conserved in bacteria
AEQU_1543	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AEQU_1545	COG0598	Magnesium transport protein CorA
AEQU_1546	COG1573	uracil-dna glycosylase
AEQU_1547	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AEQU_1548	COG0521	Mo-molybdopterin cofactor biosynthetic process
AEQU_1549	COG0303	'Molybdopterin
AEQU_1550	COG1132	(ABC) transporter
AEQU_1552	COG3976	FMN-binding domain protein
AEQU_1552	COG1053	succinate dehydrogenase
AEQU_1555	COG4716	Myosin-crossreactive antigen
AEQU_1557	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AEQU_1560	COG0203	ribosomal protein L17
AEQU_1561	COG0202	RNA polymerase activity
AEQU_1562	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AEQU_1563	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AEQU_1564	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AEQU_1565	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AEQU_1566	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AEQU_1567	COG2918	glutathione biosynthetic process
AEQU_1567	COG0189	ligase activity
AEQU_1569	COG2197	response regulator
AEQU_1572	COG2814	Major facilitator Superfamily
AEQU_1575	COG1966	Carbon starvation protein
AEQU_1580	COG0459	protein refolding
AEQU_1581	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AEQU_1582	COG2197	response regulator
AEQU_1583	COG4585	Histidine kinase
AEQU_1584	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AEQU_1584	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AEQU_1586	COG0805	protein transport
AEQU_1587	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AEQU_1589	COG0402	S-adenosylhomocysteine deaminase activity
AEQU_1593	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
AEQU_1597	COG0437	4 iron, 4 sulfur cluster binding
AEQU_1599	COG0243	molybdopterin cofactor binding
AEQU_1600	COG0330	HflC and HflK could
AEQU_1603	COG0745	RESPONSE REGULATOR receiver
AEQU_1604	COG2205	protein histidine kinase activity
AEQU_1605	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AEQU_1607	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AEQU_1610	COG0802	atpase or kinase
AEQU_1611	COG2116	formate transmembrane transporter activity
AEQU_1612	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AEQU_1613	COG3404	Formiminotransferase-cyclodeaminase
AEQU_1615	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AEQU_1616	COG0745	RESPONSE REGULATOR receiver
AEQU_1617	COG1268	BioY protein
AEQU_1619	COG0437	4 iron, 4 sulfur cluster binding
AEQU_1620	COG0243	molybdopterin cofactor binding
AEQU_1623	COG1053	succinate dehydrogenase
AEQU_1627	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AEQU_1628	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AEQU_1630	COG0424	maF-like protein
AEQU_1631	COG0037	tRNA processing
AEQU_1632	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AEQU_1633	COG1950	PFAM Membrane protein of
AEQU_1634	COG1136	(ABC) transporter
AEQU_1634	COG0577	efflux transmembrane transporter activity
AEQU_1635	COG1528	Iron-storage protein
AEQU_1636	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AEQU_1637	COG1272	protein, Hemolysin III
AEQU_1638	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AEQU_1640	COG0656	L-ascorbic acid biosynthetic process
AEQU_1641	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AEQU_1642	COG2078	PFAM AMMECR1 domain protein
AEQU_1642	COG3885	ferrous iron binding
AEQU_1643	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AEQU_1644	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AEQU_1645	COG3250	beta-galactosidase activity
AEQU_1649	COG1053	succinate dehydrogenase
AEQU_1649	COG1053	succinate dehydrogenase
AEQU_1655	COG0437	4 iron, 4 sulfur cluster binding
AEQU_1656	COG0243	molybdopterin cofactor binding
AEQU_1658	COG0656	L-ascorbic acid biosynthetic process
AEQU_1660	COG1490	D-aminoacyl-tRNA deacylase activity
AEQU_1661	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AEQU_1665	COG1053	succinate dehydrogenase
AEQU_1667	COG1373	ATPase (AAA superfamily
AEQU_1669	COG0613	PHP domain protein
AEQU_1670	COG4778	phosphonate C-P lyase system protein PhnL
AEQU_1671	COG3454	Phosphonate metabolism
AEQU_1672	COG4107	phosphonate C-P lyase system protein PhnK
AEQU_1673	COG3627	carbon phosphorus lyase activity
AEQU_1677	COG3639	organic phosphonate transmembrane transporter activity
AEQU_1678	COG3639	organic phosphonate transmembrane transporter activity
AEQU_1679	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AEQU_1682	COG1115	amino acid carrier protein
AEQU_1683	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AEQU_1685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AEQU_1685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AEQU_1688	COG1132	(ABC) transporter
AEQU_1689	COG3973	AAA domain
AEQU_1692	COG1234	tRNA 3'-trailer cleavage
AEQU_1694	COG2205	protein histidine kinase activity
AEQU_1694	COG0784	Response regulator, receiver
AEQU_1702	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AEQU_1702	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AEQU_1706	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AEQU_1711	COG3550	peptidyl-serine autophosphorylation
AEQU_1713	COG1028	Short-chain dehydrogenase reductase Sdr
AEQU_1715	COG3976	FMN-binding domain protein
AEQU_1715	COG1053	succinate dehydrogenase
AEQU_1716	COG0446	pyridine nucleotide-disulphide oxidoreductase
AEQU_1719	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AEQU_1721	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
AEQU_1723	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AEQU_1727	COG0549	Belongs to the carbamate kinase family
AEQU_1730	COG2153	protein acetylation
AEQU_1733	COG0659	secondary active sulfate transmembrane transporter activity
AEQU_1734	COG1053	succinate dehydrogenase
AEQU_1738	COG0569	domain protein
AEQU_1739	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AEQU_1742	COG2832	Protein of unknown function (DUF454)
AEQU_1743	COG0363	glucosamine-6-phosphate deaminase activity
AEQU_1744	COG0659	secondary active sulfate transmembrane transporter activity
AEQU_1745	COG1028	Short-chain dehydrogenase reductase Sdr
AEQU_1757	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AEQU_1758	COG0732	type I restriction modification DNA specificity domain
AEQU_1762	COG3328	transposase activity
AEQU_1768	COG3177	Filamentation induced by cAMP protein fic
AEQU_1772	COG0640	Transcriptional regulator
AEQU_1773	COG2217	Heavy metal translocating P-type atpase
AEQU_1774	COG2217	Heavy metal translocating P-type atpase
AEQU_1777	COG0222	ribosome binding
AEQU_1778	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AEQU_1779	COG2197	response regulator
AEQU_1780	COG1053	succinate dehydrogenase
AEQU_1782	COG1487	ribonuclease activity
AEQU_1784	COG0124	histidyl-tRNA synthetase
AEQU_1785	COG0473	3-isopropylmalate dehydrogenase activity
AEQU_1786	COG0066	3-isopropylmalate dehydratase activity
AEQU_1789	COG0142	geranyltranstransferase activity
AEQU_1792	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AEQU_1792	COG3976	FMN-binding domain protein
AEQU_1794	COG0437	4 iron, 4 sulfur cluster binding
AEQU_1795	COG0243	molybdopterin cofactor binding
AEQU_1797	COG0745	RESPONSE REGULATOR receiver
AEQU_1798	COG5002	protein histidine kinase activity
AEQU_1804	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AEQU_1804	COG1918	ferrous iron import across plasma membrane
AEQU_1823	COG1131	(ABC) transporter
AEQU_1824	COG4585	Histidine kinase
AEQU_1825	COG2197	response regulator
AEQU_1826	COG4977	sequence-specific DNA binding
AEQU_1826	COG1917	Cupin 2, conserved barrel domain protein
AEQU_1827	COG0697	spore germination
AEQU_1831	COG3177	Filamentation induced by cAMP protein fic
AEQU_1834	COG0437	4 iron, 4 sulfur cluster binding
AEQU_1835	COG0243	molybdopterin cofactor binding
AEQU_1837	COG2197	response regulator
AEQU_1840	COG3381	protein complex oligomerization
AEQU_1842	COG0348	domain, Protein
AEQU_1845	COG0437	4 iron, 4 sulfur cluster binding
AEQU_1853	COG1131	(ABC) transporter
AEQU_1858	COG1136	(ABC) transporter
AEQU_1859	COG5002	protein histidine kinase activity
AEQU_1860	COG0745	RESPONSE REGULATOR receiver
AEQU_1861	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AEQU_1863	COG1309	transcriptional regulator
AEQU_1867	COG0784	Response regulator, receiver
AEQU_1867	COG2205	protein histidine kinase activity
AEQU_1868	COG0495	leucyl-tRNA aminoacylation
AEQU_1870	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AEQU_1872	COG0583	DNA-binding transcription factor activity
AEQU_1877	COG1592	Rubrerythrin
AEQU_1878	COG1362	aminopeptidase activity
AEQU_1879	COG2957	Belongs to the agmatine deiminase family
AEQU_1880	COG0531	amino acid
AEQU_1881	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AEQU_1885	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AEQU_1886	COG2814	Major facilitator Superfamily
AEQU_1890	COG0745	RESPONSE REGULATOR receiver
AEQU_1891	COG5002	protein histidine kinase activity
AEQU_1891	COG3850	Histidine kinase
AEQU_1893	COG3976	FMN-binding domain protein
AEQU_1893	COG1053	succinate dehydrogenase
AEQU_1900	COG0437	4 iron, 4 sulfur cluster binding
AEQU_1909	COG1053	succinate dehydrogenase
AEQU_1913	COG2205	protein histidine kinase activity
AEQU_1915	COG1131	(ABC) transporter
AEQU_1916	COG0745	RESPONSE REGULATOR receiver
AEQU_1922	COG0583	DNA-binding transcription factor activity
AEQU_1925	COG2814	Major facilitator Superfamily
AEQU_1926	COG0235	Class ii aldolase
AEQU_1927	COG4806	L-rhamnose isomerase
AEQU_1927	COG1070	Carbohydrate kinase
AEQU_1928	COG1070	Carbohydrate kinase
AEQU_1933	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AEQU_1934	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AEQU_1941	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AEQU_1944	COG0067	glutamate synthase
AEQU_1945	COG0069	glutamate synthase activity
AEQU_1947	COG1053	succinate dehydrogenase
AEQU_1953	COG2909	trisaccharide binding
AEQU_1954	COG1053	succinate dehydrogenase
AEQU_1957	COG0437	4 iron, 4 sulfur cluster binding
AEQU_1959	COG0583	DNA-binding transcription factor activity
AEQU_1972	COG1396	sequence-specific DNA binding
AEQU_1975	COG0460	homoserine dehydrogenase
AEQU_1977	COG0019	diaminopimelate decarboxylase activity
AEQU_1981	COG0733	neurotransmitter:sodium symporter activity
AEQU_1984	COG0398	Pfam SNARE associated Golgi protein
AEQU_1987	COG1181	Belongs to the D-alanine--D-alanine ligase family
AEQU_1988	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AEQU_1991	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AEQU_1993	COG2815	serine threonine protein kinase
AEQU_1993	COG0515	serine threonine protein kinase
AEQU_1994	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AEQU_1997	COG3275	phosphorelay sensor kinase activity
AEQU_1998	COG0730	response to heat
AEQU_2000	COG1162	GTPase activity
AEQU_2002	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AEQU_2003	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AEQU_2004	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AEQU_2006	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AEQU_2007	COG5002	protein histidine kinase activity
AEQU_2008	COG0745	RESPONSE REGULATOR receiver
AEQU_2010	COG1472	Belongs to the glycosyl hydrolase 3 family
AEQU_2011	COG0785	Cytochrome C biogenesis protein
AEQU_2012	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AEQU_2013	COG1053	succinate dehydrogenase
AEQU_2016	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AEQU_2021	COG2239	Acts as a magnesium transporter
AEQU_2023	COG1959	2 iron, 2 sulfur cluster binding
AEQU_2024	COG1757	Na H antiporter
AEQU_2028	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AEQU_2029	COG1169	isochorismate synthase
AEQU_2030	COG3830	Belongs to the UPF0237 family
AEQU_2031	COG0302	gtp cyclohydrolase
AEQU_2032	COG1970	mechanosensitive ion channel activity
AEQU_2035	COG0437	4 iron, 4 sulfur cluster binding
AEQU_2036	COG0243	molybdopterin cofactor binding
AEQU_2038	COG0708	Exodeoxyribonuclease III
AEQU_2040	COG1316	TRANSCRIPTIONal
AEQU_2042	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AEQU_2046	COG0437	4 iron, 4 sulfur cluster binding
AEQU_2047	COG0243	molybdopterin cofactor binding
AEQU_2048	COG0583	DNA-binding transcription factor activity
AEQU_2049	COG1053	succinate dehydrogenase
AEQU_2051	COG3177	Filamentation induced by cAMP protein fic
AEQU_2053	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AEQU_2054	COG3189	MarR family transcriptional regulator
AEQU_2055	COG2233	PERMEase
AEQU_2056	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AEQU_2058	COG2197	response regulator
AEQU_2061	COG3706	GGDEF domain
AEQU_2066	COG0025	NhaP-type Na H and K H
AEQU_2067	COG0519	Catalyzes the synthesis of GMP from XMP
AEQU_2070	COG1073	alpha beta
AEQU_2071	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AEQU_2073	COG1396	sequence-specific DNA binding
AEQU_2079	COG2207	Transcriptional regulator
AEQU_2079	COG3708	Transcriptional regulator
AEQU_2080	COG0456	acetyltransferase
AEQU_2081	COG0477	Major facilitator Superfamily
AEQU_2085	COG2066	Belongs to the glutaminase family
AEQU_2086	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AEQU_2088	COG1715	Restriction endonuclease
AEQU_2095	COG0789	Transcriptional regulator
AEQU_2097	COG1393	Belongs to the ArsC family
AEQU_2099	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AEQU_2106	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AEQU_2110	COG0531	amino acid
AEQU_2115	COG1053	succinate dehydrogenase
AEQU_2116	COG2197	response regulator
AEQU_2117	COG3976	FMN-binding domain protein
AEQU_2117	COG1053	succinate dehydrogenase
AEQU_2117	COG0431	NADPH-dependent FMN reductase
AEQU_2118	COG0431	NADPH-dependent FMN reductase
AEQU_2118	COG3976	FMN-binding domain protein
AEQU_2118	COG1053	succinate dehydrogenase
AEQU_2122	COG1120	ATPase activity
AEQU_2125	COG0745	RESPONSE REGULATOR receiver
AEQU_2126	COG5002	protein histidine kinase activity
AEQU_2129	COG1733	regulation of RNA biosynthetic process
AEQU_2132	COG3093	addiction module antidote protein HigA
AEQU_2136	COG0433	COG0433 Predicted ATPase
AEQU_2137	COG0390	transport system, permease component
AEQU_2138	COG3842	ATPase activity
AEQU_2150	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AEQU_2158	COG0784	Response regulator, receiver
AEQU_2158	COG2205	protein histidine kinase activity
AEQU_2160	COG3437	response regulator, receiver
AEQU_2163	COG0745	RESPONSE REGULATOR receiver
AEQU_2164	COG2205	protein histidine kinase activity
AEQU_2165	COG0437	4 iron, 4 sulfur cluster binding
AEQU_2167	COG0243	molybdopterin cofactor binding
AEQU_2180	COG1846	Transcriptional regulator
AEQU_2182	COG0765	amino acid transport
AEQU_2183	COG1126	abc transporter atp-binding protein
AEQU_2184	COG1842	Phage shock protein A
AEQU_2191	COG0631	protein serine/threonine phosphatase activity
AEQU_2193	COG0515	serine threonine protein kinase
AEQU_2193	COG2815	serine threonine protein kinase
AEQU_2196	COG5002	protein histidine kinase activity
AEQU_2197	COG0745	RESPONSE REGULATOR receiver
AEQU_2198	COG1283	sodium-dependent phosphate transmembrane transporter activity
AEQU_2199	COG0581	inorganic phosphate transmembrane transporter activity
AEQU_2200	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AEQU_2201	COG0573	inorganic phosphate transmembrane transporter activity
AEQU_2202	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AEQU_2203	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AEQU_2203	COG3976	FMN-binding domain protein
AEQU_2205	COG0437	4 iron, 4 sulfur cluster binding
AEQU_2206	COG0243	molybdopterin cofactor binding
AEQU_2207	COG0243	molybdopterin cofactor binding
AEQU_2208	COG0583	DNA-binding transcription factor activity
AEQU_2212	COG1328	CTP reductase activity
AEQU_2219	COG1511	domain protein
AEQU_2221	COG1160	GTP binding
AEQU_2223	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AEQU_2226	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AEQU_2227	COG0644	oxidoreductase
AEQU_2228	COG1902	pentaerythritol trinitrate reductase activity
AEQU_2228	COG0446	pyridine nucleotide-disulphide oxidoreductase
AEQU_2230	COG1028	Short-chain dehydrogenase reductase Sdr
AEQU_2231	COG0431	NADPH-dependent FMN reductase
AEQU_2231	COG1053	succinate dehydrogenase
AEQU_2231	COG3976	FMN-binding domain protein
AEQU_2238	COG3177	Filamentation induced by cAMP protein fic
AEQU_2241	COG1053	succinate dehydrogenase
AEQU_2245	COG1979	alcohol dehydrogenase
AEQU_2248	COG0726	polysaccharide deacetylase
AEQU_2249	COG1045	serine acetyltransferase
AEQU_2250	COG2814	Major facilitator Superfamily
AEQU_2251	COG1253	flavin adenine dinucleotide binding
AEQU_2253	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AEQU_2260	COG3328	transposase activity
AEQU_2269	COG1215	transferase activity, transferring glycosyl groups
AEQU_2277	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AEQU_2278	COG0187	DNA topoisomerase II activity
AEQU_2279	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP