locus-tag	class	description
MIM_24p00020	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MIM_24p00090	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MIM_24p00100	COG0066	3-isopropylmalate dehydratase activity
MIM_24p00120	COG2801	Transposase and inactivated derivatives
MIM_24p00150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MIM_24p00160	COG2801	Transposase and inactivated derivatives
MIM_24p00170	COG4974	Belongs to the 'phage' integrase family
MIM_24p00210	COG3041	Addiction module toxin RelE StbE family
MIM_24p00220	COG3077	Addiction module antitoxin, RelB DinJ family
MIM_24p00230	COG1192	Involved in chromosome partitioning
MIM_c00050	COG2207	Transcriptional regulator
MIM_c00050	COG1917	Cupin 2, conserved barrel domain protein
MIM_c00080	COG4574	serine-type endopeptidase inhibitor activity
MIM_c00110	COG1181	Belongs to the D-alanine--D-alanine ligase family
MIM_c00160	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c00170	COG1733	regulation of RNA biosynthetic process
MIM_c00190	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MIM_c00210	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MIM_c00220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MIM_c00240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_c00340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIM_c00350	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MIM_c00410	COG2011	ABC-type metal ion transport system permease component
MIM_c00420	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MIM_c00430	COG1464	Belongs to the NlpA lipoprotein family
MIM_c00450	COG0477	Major facilitator Superfamily
MIM_c00500	COG0028	Belongs to the TPP enzyme family
MIM_c00540	COG4948	Mandelate Racemase Muconate Lactonizing
MIM_c00550	COG2186	Transcriptional regulator
MIM_c00580	COG0395	ABC-type sugar transport system, permease component
MIM_c00590	COG3842	ATPase activity
MIM_c00660	COG4585	Histidine kinase
MIM_c00700	COG4669	(LipO)protein
MIM_c00730	COG1157	protein secretion by the type III secretion system
MIM_c00750	COG4790	Type iii secretion
MIM_c00770	COG4791	protein targeting
MIM_c00780	COG4792	protein secretion
MIM_c00810	COG4789	Type iii secretion
MIM_c00820	COG4964	Belongs to the GSP D family
MIM_c00900	COG0583	DNA-binding transcription factor activity
MIM_c00910	COG2814	Major facilitator Superfamily
MIM_c00920	COG2814	Major facilitator Superfamily
MIM_c00930	COG4774	siderophore transport
MIM_c00940	COG0625	glutathione transferase activity
MIM_c00950	COG1733	regulation of RNA biosynthetic process
MIM_c00970	COG0488	(ABC) transporter
MIM_c00990	COG5285	phytanoyl-CoA dioxygenase
MIM_c01000	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MIM_c01010	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c01020	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MIM_c01080	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MIM_c01110	COG0318	PFAM AMP-dependent synthetase and ligase
MIM_c01150	COG0559	Belongs to the binding-protein-dependent transport system permease family
MIM_c01180	COG0410	ABC transporter
MIM_c01190	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MIM_c01200	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c01220	COG5339	Protein conserved in bacteria
MIM_c01230	COG0251	oxidation-reduction process
MIM_c01250	COG1250	3-hydroxyacyl-CoA dehydrogenase
MIM_c01260	COG3257	ureidoglycine aminohydrolase activity
MIM_c01270	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
MIM_c01280	COG1301	dicarboxylic acid transport
MIM_c01320	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MIM_c01330	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MIM_c01360	COG0583	DNA-binding transcription factor activity
MIM_c01370	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c01400	COG0673	inositol 2-dehydrogenase activity
MIM_c01450	COG0590	tRNA wobble adenosine to inosine editing
MIM_c01460	COG2807	transmembrane transport
MIM_c01480	COG0583	DNA-binding transcription factor activity
MIM_c01490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIM_c01500	COG0431	NADPH-dependent FMN reductase
MIM_c01510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MIM_c01520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_c01540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIM_c01550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIM_c01570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_c01600	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MIM_c01620	COG3473	Maleate cis-trans isomerase
MIM_c01660	COG1573	uracil-dna glycosylase
MIM_c01690	COG2814	Major facilitator Superfamily
MIM_c01700	COG0583	DNA-binding transcription factor activity
MIM_c01710	COG1609	Transcriptional regulator
MIM_c01760	COG0861	Integral membrane protein TerC family
MIM_c01770	COG2119	membrane
MIM_c01800	COG4771	TonB-dependent receptor
MIM_c01820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIM_c01830	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
MIM_c01880	COG2814	Major facilitator Superfamily
MIM_c01960	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MIM_c01960	COG2010	Cytochrome c
MIM_c01980	COG0683	leucine binding
MIM_c01990	COG0559	Belongs to the binding-protein-dependent transport system permease family
MIM_c02010	COG0411	ABC transporter
MIM_c02040	COG0596	Alpha beta hydrolase
MIM_c02050	COG2309	aminopeptidase activity
MIM_c02060	COG1335	isochorismatase
MIM_c02070	COG1309	transcriptional regulator
MIM_c02080	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c02100	COG1230	cation diffusion facilitator family transporter
MIM_c02150	COG2223	nitrite transmembrane transporter activity
MIM_c02160	COG2207	Transcriptional regulator
MIM_c02180	COG5383	Protein conserved in bacteria
MIM_c02190	COG4607	ABC-type enterochelin transport system periplasmic component
MIM_c02200	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIM_c02210	COG4605	iron ion homeostasis
MIM_c02220	COG4604	ABC transporter, ATP-binding protein
MIM_c02230	COG0668	transmembrane transport
MIM_c02240	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c02270	COG3284	Transcriptional regulator
MIM_c02280	COG1012	belongs to the aldehyde dehydrogenase family
MIM_c02300	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MIM_c02320	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MIM_c02320	COG3608	succinylglutamate desuccinylase aspartoacylase
MIM_c02350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MIM_c02420	COG0024	Methionine aminopeptidase
MIM_c02430	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MIM_c02440	COG3189	MarR family transcriptional regulator
MIM_c02450	COG4993	Dehydrogenase
MIM_c02460	COG4772	TonB-dependent receptor
MIM_c02470	COG1414	Transcriptional regulator
MIM_c02480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MIM_c02490	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_c02530	COG1560	Kdo2-lipid A biosynthetic process
MIM_c02540	COG0432	Pfam Uncharacterised protein family UPF0047
MIM_c02570	COG0583	DNA-binding transcription factor activity
MIM_c02610	COG1131	(ABC) transporter
MIM_c02620	COG0842	Transport permease protein
MIM_c02650	COG3448	diguanylate cyclase activity
MIM_c02650	COG4175	Glycine betaine
MIM_c02660	COG4176	ABC-type proline glycine betaine transport system permease component
MIM_c02710	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_c02750	COG2129	metallophosphoesterase
MIM_c02800	COG4166	transmembrane transport
MIM_c02810	COG0444	Belongs to the ABC transporter superfamily
MIM_c02820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIM_c02830	COG0601	transmembrane transport
MIM_c02840	COG4608	Belongs to the ABC transporter superfamily
MIM_c02850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MIM_c02880	COG0210	DNA helicase
MIM_c02890	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MIM_c02960	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MIM_c02970	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
MIM_c03000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MIM_c03010	COG3422	double-strand break repair
MIM_c03020	COG5339	Protein conserved in bacteria
MIM_c03050	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MIM_c03060	COG0028	Belongs to the TPP enzyme family
MIM_c03090	COG2072	flavoprotein involved in K transport
MIM_c03100	COG0601	transmembrane transport
MIM_c03110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIM_c03120	COG0444	Belongs to the ABC transporter superfamily
MIM_c03130	COG4608	Belongs to the ABC transporter superfamily
MIM_c03140	COG0747	negative chemotaxis
MIM_c03200	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MIM_c03230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MIM_c03240	COG2922	Belongs to the Smg family
MIM_c03250	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MIM_c03280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MIM_c03290	COG0183	Belongs to the thiolase family
MIM_c03300	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
MIM_c03310	COG1960	acyl-CoA dehydrogenase activity
MIM_c03330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MIM_c03340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MIM_c03380	COG1960	acyl-CoA dehydrogenase activity
MIM_c03410	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c03430	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c03440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_c03450	COG1024	Enoyl-CoA hydratase
MIM_c03460	COG2188	Transcriptional regulator
MIM_c03470	COG1280	lysine exporter protein (LysE YggA)
MIM_c03490	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
MIM_c03510	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MIM_c03530	COG0018	arginyl-trna synthetase
MIM_c03560	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MIM_c03580	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MIM_c03590	COG2193	ferroxidase activity
MIM_c03610	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MIM_c03630	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MIM_c03640	COG0583	DNA-binding transcription factor activity
MIM_c03650	COG2986	histidine ammonia-lyase
MIM_c03700	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MIM_c03710	COG1160	GTP binding
MIM_c03790	COG3842	ATPase activity
MIM_c03800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MIM_c03810	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MIM_c03810	COG0678	peroxiredoxin activity
MIM_c03820	COG2431	L-lysine efflux transmembrane transporter activity
MIM_c03850	COG4215	(ABC) transporter
MIM_c03860	COG4160	amino acid transport
MIM_c03870	COG4598	ABC transporter
MIM_c03880	COG0730	response to heat
MIM_c03900	COG3045	CreA protein
MIM_c03920	COG0405	Gamma-glutamyltransferase
MIM_c03970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_c03980	COG1116	anion transmembrane transporter activity
MIM_c04000	COG2175	clavaminate synthase activity
MIM_c04010	COG1741	Belongs to the pirin family
MIM_c04070	COG3038	cytochrome b561
MIM_c04130	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c04220	COG0697	spore germination
MIM_c04230	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MIM_c04240	COG1127	ABC transporter
MIM_c04270	COG2079	MmgE PrpD family protein
MIM_c04320	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MIM_c04330	COG0066	3-isopropylmalate dehydratase activity
MIM_c04370	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MIM_c04380	COG0066	3-isopropylmalate dehydratase activity
MIM_c04390	COG0318	PFAM AMP-dependent synthetase and ligase
MIM_c04410	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c04450	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MIM_c04460	COG1522	sequence-specific DNA binding
MIM_c04480	COG0463	Glycosyl transferase, family 2
MIM_c04490	COG2814	Major facilitator Superfamily
MIM_c04500	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MIM_c04520	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
MIM_c04530	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MIM_c04540	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MIM_c04600	COG1612	heme a metabolic process
MIM_c04610	COG0109	protoheme IX farnesyltransferase activity
MIM_c04620	COG1999	signal sequence binding
MIM_c04640	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MIM_c04650	COG4521	taurine ABC transporter
MIM_c04670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_c04700	COG1368	sulfuric ester hydrolase activity
MIM_c04710	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MIM_c04720	COG0513	Belongs to the DEAD box helicase family
MIM_c04730	COG0070	glutamate synthase
MIM_c04730	COG0067	glutamate synthase
MIM_c04730	COG0069	glutamate synthase activity
MIM_c04750	COG1127	ABC transporter
MIM_c04760	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MIM_c04770	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MIM_c04780	COG2853	Lipoprotein
MIM_c04800	COG1131	(ABC) transporter
MIM_c04810	COG0842	Transport permease protein
MIM_c04830	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MIM_c04840	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MIM_c04850	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MIM_c04860	COG0131	Imidazoleglycerol-phosphate dehydratase
MIM_c04870	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MIM_c04880	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MIM_c04890	COG0107	imidazoleglycerol-phosphate synthase activity
MIM_c04900	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MIM_c04910	COG0140	phosphoribosyl-ATP diphosphatase activity
MIM_c04920	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MIM_c04940	COG0805	protein transport
MIM_c04950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MIM_c04960	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MIM_c04970	COG1970	mechanosensitive ion channel activity
MIM_c04980	COG0723	plastoquinol--plastocyanin reductase activity
MIM_c04990	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MIM_c05000	COG2857	Cytochrome c1
MIM_c05010	COG0625	glutathione transferase activity
MIM_c05020	COG2969	positive regulation of protein catabolic process
MIM_c05040	COG2096	Adenosyltransferase
MIM_c05060	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MIM_c05070	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MIM_c05080	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MIM_c05090	COG0523	cobalamin synthesis protein
MIM_c05100	COG0735	belongs to the Fur family
MIM_c05120	COG1121	(ABC) transporter
MIM_c05130	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MIM_c05140	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MIM_c05160	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MIM_c05170	COG1560	Kdo2-lipid A biosynthetic process
MIM_c05180	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MIM_c05190	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MIM_c05200	COG1950	PFAM Membrane protein of
MIM_c05210	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MIM_c05220	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MIM_c05240	COG0617	tRNA 3'-terminal CCA addition
MIM_c05320	COG0513	Belongs to the DEAD box helicase family
MIM_c05340	COG0134	indole-3-glycerol-phosphate synthase activity
MIM_c05350	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MIM_c05360	COG0512	Glutamine amidotransferase of anthranilate synthase
MIM_c05380	COG0546	phosphoglycolate phosphatase activity
MIM_c05400	COG2967	ApaG domain
MIM_c05420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MIM_c05430	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MIM_c05450	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MIM_c05470	COG2823	Periplasmic or secreted lipoprotein
MIM_c05480	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
MIM_c05510	COG1660	Displays ATPase and GTPase activities
MIM_c05520	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MIM_c05540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MIM_c05550	COG1137	ATPase activity
MIM_c05580	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MIM_c05600	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MIM_c05610	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MIM_c05620	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MIM_c05630	COG1238	metal cluster binding
MIM_c05650	COG1984	allophanate hydrolase subunit 2
MIM_c05660	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MIM_c05690	COG2226	methyltransferase
MIM_c05710	COG1116	anion transmembrane transporter activity
MIM_c05760	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MIM_c05770	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MIM_c05800	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MIM_c05810	COG0351	phosphomethylpyrimidine kinase
MIM_c05820	COG2326	polyphosphate kinase activity
MIM_c05850	COG0791	NLP P60 protein
MIM_c05860	COG1902	pentaerythritol trinitrate reductase activity
MIM_c05870	COG1737	Transcriptional regulator
MIM_c05890	COG4172	Belongs to the ABC transporter superfamily
MIM_c05900	COG0747	negative chemotaxis
MIM_c05910	COG0601	transmembrane transport
MIM_c05920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIM_c05960	COG1794	racemase activity, acting on amino acids and derivatives
MIM_c05980	COG0583	DNA-binding transcription factor activity
MIM_c06000	COG3386	PFAM SMP-30 Gluconolaconase
MIM_c06030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MIM_c06050	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MIM_c06060	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
MIM_c06070	COG3639	organic phosphonate transmembrane transporter activity
MIM_c06080	COG2188	Transcriptional regulator
MIM_c06090	COG3624	Phosphonate C-P lyase system protein PhnG
MIM_c06110	COG3626	phosphonate metabolism
MIM_c06120	COG3627	carbon phosphorus lyase activity
MIM_c06130	COG4107	phosphonate C-P lyase system protein PhnK
MIM_c06140	COG4778	phosphonate C-P lyase system protein PhnL
MIM_c06150	COG3454	Phosphonate metabolism
MIM_c06170	COG1234	tRNA 3'-trailer cleavage
MIM_c06220	COG0668	transmembrane transport
MIM_c06260	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_c06270	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MIM_c06280	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c06320	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MIM_c06340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_c06350	COG0473	3-isopropylmalate dehydrogenase activity
MIM_c06360	COG0252	asparaginase activity
MIM_c06370	COG0667	Aldo Keto reductase
MIM_c06390	COG0145	ligase activity
MIM_c06400	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
MIM_c06410	COG4647	ligase activity
MIM_c06420	COG2610	gluconate transmembrane transporter activity
MIM_c06450	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIM_c06560	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MIM_c06570	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MIM_c06570	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MIM_c06570	COG0506	proline dehydrogenase activity
MIM_c06580	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MIM_c06590	COG1956	GAF domain-containing protein
MIM_c06620	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MIM_c06630	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c06670	COG2321	neutral zinc metallopeptidase
MIM_c06680	COG1994	Peptidase M50
MIM_c06690	COG3568	Endonuclease Exonuclease Phosphatase
MIM_c06700	COG0859	PFAM glycosyl transferase family 9
MIM_c06720	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MIM_c06720	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MIM_c06730	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MIM_c06740	COG2945	thiolester hydrolase activity
MIM_c06750	COG1686	Belongs to the peptidase S11 family
MIM_c06770	COG2921	Belongs to the UPF0250 family
MIM_c06780	COG0321	lipoyl(octanoyl) transferase activity
MIM_c06800	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MIM_c06810	COG0438	transferase activity, transferring glycosyl groups
MIM_c06820	COG0166	Belongs to the GPI family
MIM_c06830	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MIM_c06850	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
MIM_c06860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MIM_c06920	COG0297	glycogen (starch) synthase activity
MIM_c06950	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MIM_c06950	COG2755	lipolytic protein G-D-S-L family
MIM_c06960	COG1946	Acyl-CoA thioesterase
MIM_c06990	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MIM_c07080	COG0095	Lipoate-protein ligase
MIM_c07090	COG0242	peptide deformylase activity
MIM_c07100	COG0758	DNA mediated transformation
MIM_c07110	COG0431	NADPH-dependent FMN reductase
MIM_c07150	COG0477	Major facilitator Superfamily
MIM_c07180	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MIM_c07190	COG0546	phosphoglycolate phosphatase activity
MIM_c07230	COG5000	phosphorelay sensor kinase activity
MIM_c07240	COG2204	response regulator
MIM_c07250	COG0569	domain protein
MIM_c07260	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MIM_c07270	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MIM_c07300	COG0765	amino acid transport
MIM_c07310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIM_c07330	COG1040	competence protein
MIM_c07340	COG2226	methyltransferase
MIM_c07350	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MIM_c07360	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
MIM_c07370	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MIM_c07380	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MIM_c07390	COG0588	phosphoglycerate mutase activity
MIM_c07400	COG4942	peptidase
MIM_c07410	COG0793	Belongs to the peptidase S41A family
MIM_c07440	COG1024	Enoyl-CoA hydratase
MIM_c07460	COG0356	it plays a direct role in the translocation of protons across the membrane
MIM_c07480	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MIM_c07490	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MIM_c07500	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MIM_c07510	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MIM_c07520	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MIM_c07530	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MIM_c07540	COG1473	amidohydrolase
MIM_c07570	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c07600	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MIM_c07610	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MIM_c07720	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MIM_c07810	COG2003	Belongs to the UPF0758 family
MIM_c07820	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MIM_c07830	COG3077	Addiction module antitoxin, RelB DinJ family
MIM_c07840	COG1132	(ABC) transporter
MIM_c07850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MIM_c07870	COG4948	Mandelate Racemase Muconate Lactonizing
MIM_c07880	COG0583	DNA-binding transcription factor activity
MIM_c07890	COG4977	sequence-specific DNA binding
MIM_c07890	COG1917	Cupin 2, conserved barrel domain protein
MIM_c07910	COG2885	chlorophyll binding
MIM_c07910	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MIM_c07920	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MIM_c08030	COG0601	transmembrane transport
MIM_c08040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIM_c08050	COG4608	Belongs to the ABC transporter superfamily
MIM_c08060	COG0444	Belongs to the ABC transporter superfamily
MIM_c08080	COG0154	amidase activity
MIM_c08090	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MIM_c08100	COG0477	Major facilitator Superfamily
MIM_c08120	COG0252	asparaginase activity
MIM_c08160	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MIM_c08170	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MIM_c08190	COG1850	ribulose-bisphosphate carboxylase activity
MIM_c08240	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_c08260	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c08280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MIM_c08290	COG0765	amino acid transport
MIM_c08300	COG0765	amino acid transport
MIM_c08310	COG1126	abc transporter atp-binding protein
MIM_c08360	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MIM_c08380	COG0753	catalase activity
MIM_c08430	COG0583	DNA-binding transcription factor activity
MIM_c08460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIM_c08480	COG0765	amino acid transport
MIM_c08490	COG1126	abc transporter atp-binding protein
MIM_c08500	COG0583	DNA-binding transcription factor activity
MIM_c08520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_c08550	COG1024	Enoyl-CoA hydratase
MIM_c08560	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_c08580	COG1024	Enoyl-CoA hydratase
MIM_c08590	COG0318	PFAM AMP-dependent synthetase and ligase
MIM_c08600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MIM_c08610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MIM_c08620	COG0251	oxidation-reduction process
MIM_c08660	COG1177	transmembrane transport
MIM_c08670	COG1176	ABC-type spermidine putrescine transport system, permease component I
MIM_c08680	COG3842	ATPase activity
MIM_c08730	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c08750	COG1301	dicarboxylic acid transport
MIM_c08770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIM_c08780	COG4215	(ABC) transporter
MIM_c08790	COG4160	amino acid transport
MIM_c08820	COG2918	glutathione biosynthetic process
MIM_c08840	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MIM_c08850	COG2813	Specifically methylates the guanine in position
MIM_c08850	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MIM_c08860	COG2223	nitrite transmembrane transporter activity
MIM_c08880	COG2010	Cytochrome c
MIM_c08890	COG0708	Exodeoxyribonuclease III
MIM_c08910	COG3384	dioxygenase
MIM_c08920	COG2259	Doxx family
MIM_c08930	COG0583	DNA-binding transcription factor activity
MIM_c08950	COG1132	(ABC) transporter
MIM_c08970	COG4773	Receptor
MIM_c08990	COG4774	siderophore transport
MIM_c09000	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MIM_c09010	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MIM_c09020	COG0154	amidase activity
MIM_c09030	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MIM_c09040	COG1077	Cell shape determining protein MreB Mrl
MIM_c09050	COG1792	Involved in formation and maintenance of cell shape
MIM_c09070	COG0768	penicillin binding
MIM_c09080	COG0772	Belongs to the SEDS family
MIM_c09090	COG1194	a g-specific adenine glycosylase
MIM_c09100	COG2177	Part of the ABC transporter FtsEX involved in
MIM_c09110	COG2884	Cell division ATP-binding protein ftsE
MIM_c09120	COG4597	amino acid ABC transporter
MIM_c09130	COG0765	amino acid transport
MIM_c09140	COG1126	abc transporter atp-binding protein
MIM_c09160	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MIM_c09170	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MIM_c09180	COG2197	response regulator
MIM_c09210	COG0237	dephospho-CoA kinase activity
MIM_c09220	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
MIM_c09230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIM_c09270	COG1045	serine acetyltransferase
MIM_c09280	COG0494	nUDIX hydrolase
MIM_c09300	COG0142	geranyltranstransferase activity
MIM_c09310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIM_c09320	COG0765	amino acid transport
MIM_c09330	COG1126	abc transporter atp-binding protein
MIM_c09340	COG0129	dihydroxy-acid dehydratase activity
MIM_c09360	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MIM_c09380	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MIM_c09400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MIM_c09410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_c09420	COG1116	anion transmembrane transporter activity
MIM_c09430	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MIM_c09450	COG0243	molybdopterin cofactor binding
MIM_c09470	COG0745	RESPONSE REGULATOR receiver
MIM_c09480	COG2205	protein histidine kinase activity
MIM_c09490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIM_c09520	COG1609	Transcriptional regulator
MIM_c09540	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c09550	COG0477	Major facilitator Superfamily
MIM_c09560	COG1063	alcohol dehydrogenase
MIM_c09600	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c09620	COG4948	Mandelate Racemase Muconate Lactonizing
MIM_c09680	COG2001	Belongs to the MraZ family
MIM_c09690	COG0275	rRNA processing
MIM_c09700	COG3116	cell division
MIM_c09720	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MIM_c09730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MIM_c09740	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MIM_c09770	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MIM_c09780	COG1181	Belongs to the D-alanine--D-alanine ligase family
MIM_c09790	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MIM_c09820	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
MIM_c09840	COG0739	heme binding
MIM_c09840	COG0741	lytic transglycosylase activity
MIM_c09840	COG1196	nuclear chromosome segregation
MIM_c09850	COG0653	protein targeting
MIM_c09860	COG2239	Acts as a magnesium transporter
MIM_c09880	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MIM_c09880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MIM_c09970	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MIM_c09980	COG4206	TonB-dependent receptor
MIM_c10000	COG4558	Periplasmic binding protein
MIM_c10010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIM_c10020	COG1120	ATPase activity
MIM_c10030	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MIM_c10060	COG2022	thiamine diphosphate biosynthetic process
MIM_c10100	COG0514	ATP-dependent DNA helicase (RecQ)
MIM_c10150	COG2255	four-way junction helicase activity
MIM_c10170	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MIM_c10180	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MIM_c10240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MIM_c10270	COG0429	hydrolase of the alpha beta-hydrolase fold
MIM_c10310	COG0513	Belongs to the DEAD box helicase family
MIM_c10350	COG1414	Transcriptional regulator
MIM_c10370	COG0167	dihydroorotate dehydrogenase activity
MIM_c10380	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
MIM_c10390	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MIM_c10420	COG2154	pterin-4-alpha-carbinolamine dehydratase
MIM_c10430	COG3186	Phenylalanine-4-hydroxylase
MIM_c10450	COG2391	methyltransferase activity
MIM_c10490	COG1690	Belongs to the RtcB family
MIM_c10490	COG1690	Belongs to the RtcB family
MIM_c10520	COG0629	single-stranded DNA binding
MIM_c10700	COG0305	Participates in initiation and elongation during chromosome replication
MIM_c10710	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
MIM_c10800	COG4626	Terminase
MIM_c10800	COG1802	Transcriptional regulator
MIM_c10820	COG0740	serine-type endopeptidase activity
MIM_c10840	COG3344	reverse transcriptase
MIM_c10940	COG3344	reverse transcriptase
MIM_c11080	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MIM_c11100	COG2010	Cytochrome c
MIM_c11120	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MIM_c11120	COG2169	Transcriptional regulator
MIM_c11130	COG0318	PFAM AMP-dependent synthetase and ligase
MIM_c11140	COG0583	DNA-binding transcription factor activity
MIM_c11210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MIM_c11230	COG0531	amino acid
MIM_c11240	COG1408	metallophosphoesterase
MIM_c11270	COG0395	ABC-type sugar transport system, permease component
MIM_c11290	COG3842	ATPase activity
MIM_c11300	COG0546	phosphoglycolate phosphatase activity
MIM_c11340	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
MIM_c11360	COG3346	SURF1 family
MIM_c11370	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MIM_c11380	COG1845	cytochrome c oxidase, subunit III
MIM_c11390	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MIM_c11400	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MIM_c11410	COG0477	Major facilitator Superfamily
MIM_c11470	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MIM_c11480	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MIM_c11490	COG0735	belongs to the Fur family
MIM_c11500	COG0497	DNA recombination
MIM_c11510	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MIM_c11520	COG1420	regulation of RNA biosynthetic process
MIM_c11530	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MIM_c11540	COG3217	Mosc domain protein beta barrel domain protein
MIM_c11540	COG0633	Ferredoxin
MIM_c11550	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MIM_c11560	COG0443	Heat shock 70 kDa protein
MIM_c11570	COG0484	heat shock protein binding
MIM_c11590	COG0725	ABC transporter, periplasmic molybdate-binding protein
MIM_c11600	COG4149	molybdate abc transporter
MIM_c11610	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MIM_c11620	COG2005	Transcriptional regulator
MIM_c11620	COG3585	molybdate ion transport
MIM_c11640	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MIM_c11710	COG4948	Mandelate Racemase Muconate Lactonizing
MIM_c11720	COG0583	DNA-binding transcription factor activity
MIM_c11730	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c11750	COG0431	NADPH-dependent FMN reductase
MIM_c11750	COG1053	succinate dehydrogenase
MIM_c11750	COG3976	FMN-binding domain protein
MIM_c11790	COG0492	ferredoxin-NADP+ reductase activity
MIM_c11800	COG1674	ftsk spoiiie
MIM_c11810	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MIM_c11820	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MIM_c11830	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MIM_c11840	COG3022	response to hydroperoxide
MIM_c11850	COG2271	Major facilitator Superfamily
MIM_c11860	COG1289	transmembrane transporter activity
MIM_c11870	COG0028	Belongs to the TPP enzyme family
MIM_c11880	COG0440	acetolactate synthase activity
MIM_c11890	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MIM_c11910	COG0436	Aminotransferase
MIM_c11980	COG1960	acyl-CoA dehydrogenase activity
MIM_c11990	COG1024	Enoyl-CoA hydratase
MIM_c12020	COG2050	protein possibly involved in aromatic compounds catabolism
MIM_c12030	COG1960	acyl-CoA dehydrogenase activity
MIM_c12040	COG1960	acyl-CoA dehydrogenase activity
MIM_c12060	COG0183	Belongs to the thiolase family
MIM_c12070	COG0318	PFAM AMP-dependent synthetase and ligase
MIM_c12090	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MIM_c12100	COG0183	Belongs to the thiolase family
MIM_c12110	COG1126	abc transporter atp-binding protein
MIM_c12120	COG0765	amino acid transport
MIM_c12130	COG0765	amino acid transport
MIM_c12150	COG0688	phosphatidylethanolamine metabolic process
MIM_c12160	COG1183	phosphatidylcholine synthase activity
MIM_c12180	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MIM_c12190	COG1185	polyribonucleotide nucleotidyltransferase activity
MIM_c12200	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MIM_c12210	COG3193	protein, possibly involved in utilization of glycolate and propanediol
MIM_c12240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MIM_c12270	COG0009	L-threonylcarbamoyladenylate synthase
MIM_c12280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MIM_c12290	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
MIM_c12300	COG2850	peptidyl-arginine hydroxylation
MIM_c12310	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MIM_c12320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIM_c12330	COG0765	amino acid transport
MIM_c12340	COG0765	amino acid transport
MIM_c12350	COG1126	abc transporter atp-binding protein
MIM_c12360	COG1335	isochorismatase
MIM_c12370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIM_c12380	COG0679	Auxin Efflux Carrier
MIM_c12390	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MIM_c12400	COG0668	transmembrane transport
MIM_c12430	COG1968	undecaprenyl-diphosphatase activity
MIM_c12440	COG2030	dehydratase
MIM_c12450	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c12460	COG0583	DNA-binding transcription factor activity
MIM_c12500	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MIM_c12540	COG1024	Enoyl-CoA hydratase
MIM_c12550	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MIM_c12580	COG0215	cysteine-tRNA ligase activity
MIM_c12600	COG0825	malonyl-CoA metabolic process
MIM_c12610	COG0037	tRNA processing
MIM_c12640	COG0583	DNA-binding transcription factor activity
MIM_c12660	COG2271	Major facilitator Superfamily
MIM_c12670	COG1802	Transcriptional regulator
MIM_c12700	COG0045	succinate-CoA ligase (ADP-forming) activity
MIM_c12700	COG1042	CoA-binding domain protein
MIM_c12700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MIM_c12710	COG1024	Enoyl-CoA hydratase
MIM_c12780	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c12790	COG0583	DNA-binding transcription factor activity
MIM_c12810	COG1737	Transcriptional regulator
MIM_c12840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIM_c12850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIM_c12860	COG1120	ATPase activity
MIM_c12890	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MIM_c12980	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MIM_c13010	COG0527	aspartate kinase activity
MIM_c13020	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIM_c13040	COG1960	acyl-CoA dehydrogenase activity
MIM_c13050	COG0598	Magnesium transport protein CorA
MIM_c13080	COG1666	GTP binding
MIM_c13090	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MIM_c13120	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MIM_c13130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MIM_c13200	COG0372	Belongs to the citrate synthase family
MIM_c13210	COG0039	L-malate dehydrogenase activity
MIM_c13240	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MIM_c13250	COG1053	succinate dehydrogenase
MIM_c13260	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MIM_c13270	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
MIM_c13280	COG0372	Belongs to the citrate synthase family
MIM_c13290	COG1846	Transcriptional regulator
MIM_c13330	COG0567	Dehydrogenase, E1 component
MIM_c13340	COG0508	dehydrogenase complex catalyzes the overall conversion of
MIM_c13350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MIM_c13360	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MIM_c13370	COG0180	Tryptophanyl-tRNA synthetase
MIM_c13380	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MIM_c13390	COG0747	negative chemotaxis
MIM_c13400	COG0601	transmembrane transport
MIM_c13410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIM_c13420	COG0444	Belongs to the ABC transporter superfamily
MIM_c13430	COG4608	Belongs to the ABC transporter superfamily
MIM_c13440	COG5265	(ABC) transporter
MIM_c13450	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c13480	COG2183	response to ionizing radiation
MIM_c13490	COG1199	ATP-dependent helicase activity
MIM_c13510	COG0564	pseudouridine synthase activity
MIM_c13530	COG3243	poly(R)-hydroxyalkanoic acid synthase
MIM_c13540	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c13550	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
MIM_c13580	COG3237	CsbD-like
MIM_c13640	COG0720	synthase
MIM_c13650	COG0602	queuosine metabolic process
MIM_c13660	COG0667	Aldo Keto reductase
MIM_c13720	COG0702	epimerase
MIM_c13750	COG0656	L-ascorbic acid biosynthetic process
MIM_c13760	COG2814	Major facilitator Superfamily
MIM_c13780	COG1960	acyl-CoA dehydrogenase activity
MIM_c13790	COG0583	DNA-binding transcription factor activity
MIM_c13800	COG0427	acetyl-CoA hydrolase
MIM_c13810	COG1024	Enoyl-CoA hydratase
MIM_c13820	COG1960	acyl-CoA dehydrogenase activity
MIM_c13880	COG3386	PFAM SMP-30 Gluconolaconase
MIM_c13910	COG0559	Belongs to the binding-protein-dependent transport system permease family
MIM_c13940	COG0410	ABC transporter
MIM_c13950	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c13960	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c13970	COG1012	belongs to the aldehyde dehydrogenase family
MIM_c13980	COG2079	MmgE PrpD family protein
MIM_c13990	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c14000	COG1012	belongs to the aldehyde dehydrogenase family
MIM_c14060	COG3093	addiction module antidote protein HigA
MIM_c14080	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MIM_c14090	COG1187	pseudouridine synthase activity
MIM_c14100	COG0779	Required for maturation of 30S ribosomal subunits
MIM_c14110	COG2251	uridine kinase activity
MIM_c14110	COG0195	Participates in both transcription termination and antitermination
MIM_c14130	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MIM_c14140	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MIM_c14160	COG2326	polyphosphate kinase activity
MIM_c14170	COG1620	l-lactate permease
MIM_c14180	COG3842	ATPase activity
MIM_c14190	COG0395	ABC-type sugar transport system, permease component
MIM_c14200	COG1175	transmembrane transport
MIM_c14230	COG0456	acetyltransferase
MIM_c14240	COG0385	Bile acid
MIM_c14250	COG3284	Transcriptional regulator
MIM_c14260	COG0535	radical SAM domain protein
MIM_c14270	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
MIM_c14280	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MIM_c14300	COG3791	Glutathione-dependent formaldehyde-activating
MIM_c14310	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
MIM_c14320	COG0191	fructose-bisphosphate aldolase activity
MIM_c14330	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MIM_c14340	COG3954	Phosphoribulokinase
MIM_c14350	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
MIM_c14360	COG0464	growth
MIM_c14380	COG1850	ribulose-bisphosphate carboxylase activity
MIM_c14450	COG2010	Cytochrome c
MIM_c14500	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIM_c14530	COG0662	Cupin 2, conserved barrel domain protein
MIM_c14540	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MIM_c14550	COG0504	CTP synthase activity
MIM_c14570	COG0477	Major facilitator Superfamily
MIM_c14580	COG0148	phosphopyruvate hydratase activity
MIM_c14590	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MIM_c14610	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MIM_c14630	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MIM_c14670	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MIM_c14700	COG0495	leucyl-tRNA aminoacylation
MIM_c14710	COG2197	response regulator
MIM_c14730	COG1611	Belongs to the LOG family
MIM_c14740	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MIM_c14740	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MIM_c14750	COG1280	lysine exporter protein (LysE YggA)
MIM_c14760	COG0501	Belongs to the peptidase M48B family
MIM_c14790	COG1722	exodeoxyribonuclease VII activity
MIM_c14800	COG0142	geranyltranstransferase activity
MIM_c14810	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MIM_c14820	COG1469	GTP cyclohydrolase I activity
MIM_c14830	COG0360	Binds together with S18 to 16S ribosomal RNA
MIM_c14840	COG2965	DNA replication, synthesis of RNA primer
MIM_c14850	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MIM_c14860	COG0359	binds to the 23S rRNA
MIM_c14870	COG0305	Participates in initiation and elongation during chromosome replication
MIM_c14890	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MIM_c14900	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MIM_c14920	COG0436	Aminotransferase
MIM_c14980	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MIM_c14990	COG1562	ergosterol biosynthetic process
MIM_c15000	COG1562	ergosterol biosynthetic process
MIM_c15010	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MIM_c15020	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c15050	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
MIM_c15060	COG2346	COG2346, Truncated hemoglobins
MIM_c15070	COG3642	lipopolysaccharide core region biosynthetic process
MIM_c15080	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MIM_c15090	COG3842	ATPase activity
MIM_c15100	COG1176	ABC-type spermidine putrescine transport system, permease component I
MIM_c15110	COG1177	transmembrane transport
MIM_c15130	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MIM_c15150	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
MIM_c15160	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MIM_c15160	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MIM_c15170	COG1643	Atp-dependent helicase
MIM_c15190	COG0438	transferase activity, transferring glycosyl groups
MIM_c15200	COG0726	polysaccharide deacetylase
MIM_c15210	COG1335	isochorismatase
MIM_c15220	COG1733	regulation of RNA biosynthetic process
MIM_c15250	COG1132	(ABC) transporter
MIM_c15270	COG1530	ribonuclease E activity
MIM_c15290	COG4771	TonB-dependent receptor
MIM_c15370	COG3258	Cytochrome c
MIM_c15430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MIM_c15440	COG2833	Protein of unknown function (DUF455)
MIM_c15450	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIM_c15470	COG0175	sulfate reduction
MIM_c15480	COG0175	sulfate reduction
MIM_c15490	COG2895	sulfate adenylyltransferase (ATP) activity
MIM_c15500	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MIM_c15510	COG4208	sulfate ABC transporter
MIM_c15520	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MIM_c15530	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MIM_c15540	COG1253	flavin adenine dinucleotide binding
MIM_c15550	COG4178	(ABC) transporter
MIM_c15560	COG2153	protein acetylation
MIM_c15570	COG3094	Invasion gene expression up-regulator, SirB
MIM_c15580	COG0730	response to heat
MIM_c15590	COG0557	exoribonuclease II activity
MIM_c15600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MIM_c15620	COG0776	regulation of translation
MIM_c15640	COG3344	reverse transcriptase
MIM_c15650	COG2354	Protein conserved in bacteria
MIM_c15690	COG0420	3'-5' exonuclease activity
MIM_c15700	COG0419	ATPase involved in DNA repair
MIM_c15710	COG0745	RESPONSE REGULATOR receiver
MIM_c15720	COG0642	Histidine kinase
MIM_c15730	COG3158	transport of potassium into the cell
MIM_c15740	COG0137	argininosuccinate synthase activity
MIM_c15750	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MIM_c15770	COG0268	Binds directly to 16S ribosomal RNA
MIM_c15780	COG0728	peptidoglycan biosynthetic process
MIM_c15800	COG0563	adenylate kinase activity
MIM_c15810	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
MIM_c15820	COG1663	tetraacyldisaccharide 4'-kinase activity
MIM_c15830	COG1570	exodeoxyribonuclease VII activity
MIM_c15840	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MIM_c15860	COG1278	Cold shock
MIM_c15870	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MIM_c15880	COG0542	response to heat
MIM_c15890	COG2995	paraquat-inducible protein a
MIM_c15900	COG3008	intermembrane lipid transfer
MIM_c15900	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MIM_c15940	COG0756	dUTP diphosphatase activity
MIM_c15960	COG0586	Pfam SNARE associated Golgi protein
MIM_c15970	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MIM_c15980	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MIM_c15990	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MIM_c16000	COG0196	riboflavin kinase activity
MIM_c16010	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MIM_c16020	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MIM_c16020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MIM_c16040	COG0210	DNA helicase
MIM_c16130	COG1671	Belongs to the UPF0178 family
MIM_c16140	COG2070	2-Nitropropane dioxygenase
MIM_c16170	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MIM_c16210	COG3618	amidohydrolase
MIM_c16270	COG4964	Belongs to the GSP D family
MIM_c16320	COG0583	DNA-binding transcription factor activity
MIM_c16330	COG1960	acyl-CoA dehydrogenase activity
MIM_c16350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_c16360	COG1960	acyl-CoA dehydrogenase activity
MIM_c16370	COG0450	alkyl hydroperoxide reductase
MIM_c16380	COG0335	large ribosomal subunit rRNA binding
MIM_c16390	COG0494	nUDIX hydrolase
MIM_c16400	COG1162	GTPase activity
MIM_c16410	COG0501	Belongs to the peptidase M48B family
MIM_c16420	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MIM_c16430	COG0736	holo-[acyl-carrier-protein] synthase activity
MIM_c16440	COG1472	Belongs to the glycosyl hydrolase 3 family
MIM_c16450	COG0322	excinuclease ABC activity
MIM_c16460	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MIM_c16480	COG2224	Isocitrate lyase
MIM_c16510	COG2086	electron transfer activity
MIM_c16530	COG0501	Belongs to the peptidase M48B family
MIM_c16550	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MIM_c16560	COG0038	chloride channel
MIM_c16570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MIM_c16590	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MIM_c16600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MIM_c16650	COG1295	ribonuclease BN
MIM_c16670	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MIM_c16680	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MIM_c16700	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MIM_c16710	COG0066	3-isopropylmalate dehydratase activity
MIM_c16720	COG0473	3-isopropylmalate dehydrogenase activity
MIM_c16730	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MIM_c16740	COG0101	tRNA pseudouridine synthase activity
MIM_c16750	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MIM_c16770	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MIM_c16780	COG0135	phosphoribosylanthranilate isomerase activity
MIM_c16790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_c16800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MIM_c16840	COG0488	(ABC) transporter
MIM_c16850	COG2890	protein-(glutamine-N5) methyltransferase activity
MIM_c16870	COG2171	N-acyltransferase activity
MIM_c16880	COG0436	Aminotransferase
MIM_c16910	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c16930	COG4948	Mandelate Racemase Muconate Lactonizing
MIM_c16950	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MIM_c16960	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MIM_c16970	COG0165	Argininosuccinate lyase
MIM_c16990	COG1285	pathogenesis
MIM_c17000	COG0697	spore germination
MIM_c17010	COG0477	Major facilitator Superfamily
MIM_c17030	COG0583	DNA-binding transcription factor activity
MIM_c17040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_c17050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MIM_c17090	COG2814	Major facilitator Superfamily
MIM_c17100	COG0625	glutathione transferase activity
MIM_c17110	COG0737	Belongs to the 5'-nucleotidase family
MIM_c17120	COG2130	NADP-dependent
MIM_c17130	COG0583	DNA-binding transcription factor activity
MIM_c17150	COG0625	glutathione transferase activity
MIM_c17170	COG3153	acetyltransferase
MIM_c17180	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MIM_c17190	COG2205	protein histidine kinase activity
MIM_c17200	COG0745	RESPONSE REGULATOR receiver
MIM_c17230	COG3328	transposase activity
MIM_c17260	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MIM_c17320	COG1522	sequence-specific DNA binding
MIM_c17350	COG4948	Mandelate Racemase Muconate Lactonizing
MIM_c17360	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c17380	COG0583	DNA-binding transcription factor activity
MIM_c17420	COG0765	amino acid transport
MIM_c17430	COG0765	amino acid transport
MIM_c17440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MIM_c17460	COG0277	FAD linked oxidase domain protein
MIM_c17480	COG1846	Transcriptional regulator
MIM_c17510	COG3971	2-oxopent-4-enoate hydratase activity
MIM_c17530	COG3384	dioxygenase
MIM_c17540	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c17550	COG1012	belongs to the aldehyde dehydrogenase family
MIM_c17560	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c17580	COG0179	Fumarylacetoacetate (FAA) hydrolase
MIM_c17590	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c17620	COG0028	Belongs to the TPP enzyme family
MIM_c17640	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c17650	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c17670	COG0633	Ferredoxin
MIM_c17670	COG0543	2 iron, 2 sulfur cluster binding
MIM_c17680	COG4638	Rieske (2fe-2S)
MIM_c17690	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c17740	COG0583	DNA-binding transcription factor activity
MIM_c17760	COG0456	acetyltransferase
MIM_c17770	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MIM_c17780	COG0662	Cupin 2, conserved barrel domain protein
MIM_c17790	COG5285	phytanoyl-CoA dioxygenase
MIM_c17820	COG0656	L-ascorbic acid biosynthetic process
MIM_c17840	COG0525	valine-tRNA ligase activity
MIM_c17850	COG0105	UTP biosynthetic process
MIM_c17860	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MIM_c17880	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MIM_c17890	COG0124	histidyl-tRNA synthetase
MIM_c17910	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MIM_c17920	COG1160	GTP binding
MIM_c17940	COG1923	regulation of RNA biosynthetic process
MIM_c17950	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MIM_c17960	COG0330	HflC and HflK could
MIM_c17970	COG0330	HflC and HflK could
MIM_c17980	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MIM_c17990	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MIM_c18010	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MIM_c18090	COG0454	-acetyltransferase
MIM_c18120	COG3042	response to heat
MIM_c18130	COG2841	Protein conserved in bacteria
MIM_c18140	COG0628	permease
MIM_c18160	COG3135	benzoate transporter
MIM_c18170	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MIM_c18190	COG0556	nucleotide-excision repair
MIM_c18220	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MIM_c18230	COG2137	regulation of response to DNA damage stimulus
MIM_c18240	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MIM_c18250	COG0583	DNA-binding transcription factor activity
MIM_c18260	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MIM_c18280	COG0045	succinate-CoA ligase (ADP-forming) activity
MIM_c18290	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MIM_c18300	COG0861	Integral membrane protein TerC family
MIM_c18310	COG0861	Integral membrane protein TerC family
MIM_c18320	COG0181	hydroxymethylbilane synthase activity
MIM_c18360	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MIM_c18400	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MIM_c18450	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MIM_c18460	COG0425	Belongs to the sulfur carrier protein TusA family
MIM_c18470	COG0228	four-way junction DNA binding
MIM_c18480	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MIM_c18490	COG0336	Belongs to the RNA methyltransferase TrmD family
MIM_c18500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIM_c18510	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MIM_c18530	COG1104	cysteine desulfurase activity
MIM_c18540	COG0822	iron-sulfur transferase activity
MIM_c18550	COG0316	Belongs to the HesB IscA family
MIM_c18560	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MIM_c18570	COG0443	Heat shock 70 kDa protein
MIM_c18580	COG0633	Ferredoxin
MIM_c18610	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MIM_c18660	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MIM_c18670	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c18680	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MIM_c18690	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MIM_c18750	COG1136	(ABC) transporter
MIM_c18760	COG0084	hydrolase, TatD family'
MIM_c18770	COG2333	competence protein COMEC
MIM_c18770	COG0658	competence protein
MIM_c18790	COG0613	PHP domain protein
MIM_c18810	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MIM_c18820	COG0584	glycerophosphoryl diester phosphodiesterase
MIM_c18830	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MIM_c18840	COG4181	ATPase activity
MIM_c18850	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MIM_c18860	COG1758	RNA polymerase activity
MIM_c18870	COG0194	GDP metabolic process
MIM_c18880	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c18900	COG1561	YicC-like family, N-terminal region
MIM_c18910	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MIM_c18920	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MIM_c18930	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MIM_c18950	COG3852	Histidine kinase
MIM_c18970	COG3842	ATPase activity
MIM_c18980	COG1178	ABC-type Fe3 transport system permease component
MIM_c18990	COG1840	ABC-type Fe3 transport system, periplasmic component
MIM_c19040	COG3842	ATPase activity
MIM_c19050	COG0395	ABC-type sugar transport system, permease component
MIM_c19060	COG1175	transmembrane transport
MIM_c19090	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MIM_c19100	COG0559	Belongs to the binding-protein-dependent transport system permease family
MIM_c19130	COG0410	ABC transporter
MIM_c19150	COG1999	signal sequence binding
MIM_c19160	COG0339	signal peptide processing
MIM_c19170	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MIM_c19180	COG4566	intracellular signal transduction
MIM_c19210	COG0508	dehydrogenase complex catalyzes the overall conversion of
MIM_c19220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MIM_c19230	COG0285	dihydrofolate synthase activity
MIM_c19250	COG1286	toxin biosynthetic process
MIM_c19280	COG2814	Major facilitator Superfamily
MIM_c19310	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MIM_c19320	COG0024	Methionine aminopeptidase
MIM_c19330	COG0052	Belongs to the universal ribosomal protein uS2 family
MIM_c19340	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MIM_c19350	COG0528	UMP kinase activity
MIM_c19360	COG0233	cytoplasmic translational termination
MIM_c19370	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MIM_c19390	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MIM_c19400	COG0750	zinc metalloprotease
MIM_c19430	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MIM_c19440	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MIM_c19450	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MIM_c19460	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MIM_c19470	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MIM_c19490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MIM_c19500	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MIM_c19550	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MIM_c19560	COG2867	negative regulation of translational initiation
MIM_c19570	COG1024	Enoyl-CoA hydratase
MIM_c19570	COG1250	3-hydroxyacyl-CoA dehydrogenase
MIM_c19580	COG0354	folic acid binding
MIM_c19590	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MIM_c19600	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MIM_c19620	COG0084	hydrolase, TatD family'
MIM_c19650	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MIM_c19660	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MIM_c19670	COG0625	glutathione transferase activity
MIM_c19680	COG0386	Belongs to the glutathione peroxidase family
MIM_c19690	COG5006	permease, DMT superfamily
MIM_c19700	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c19710	COG0697	spore germination
MIM_c19730	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MIM_c19830	COG1609	Transcriptional regulator
MIM_c19840	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MIM_c19910	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MIM_c19920	COG0583	DNA-binding transcription factor activity
MIM_c19930	COG0583	DNA-binding transcription factor activity
MIM_c19950	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MIM_c19970	COG3386	PFAM SMP-30 Gluconolaconase
MIM_c19980	COG0583	DNA-binding transcription factor activity
MIM_c19990	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MIM_c20020	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MIM_c20040	COG0154	amidase activity
MIM_c20050	COG2186	Transcriptional regulator
MIM_c20060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MIM_c20110	COG0583	DNA-binding transcription factor activity
MIM_c20140	COG1012	belongs to the aldehyde dehydrogenase family
MIM_c20140	COG2030	dehydratase
MIM_c20180	COG1960	acyl-CoA dehydrogenase activity
MIM_c20280	COG0559	Belongs to the binding-protein-dependent transport system permease family
MIM_c20290	COG0683	leucine binding
MIM_c20310	COG1012	belongs to the aldehyde dehydrogenase family
MIM_c20320	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MIM_c20330	COG0583	DNA-binding transcription factor activity
MIM_c20420	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c20450	COG4221	oxidoreductase activity
MIM_c20490	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MIM_c20500	COG1012	belongs to the aldehyde dehydrogenase family
MIM_c20510	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c20540	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MIM_c20550	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c20650	COG1250	3-hydroxyacyl-CoA dehydrogenase
MIM_c20660	COG1250	3-hydroxyacyl-CoA dehydrogenase
MIM_c20680	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c20690	COG1024	Enoyl-CoA hydratase
MIM_c20700	COG0318	PFAM AMP-dependent synthetase and ligase
MIM_c20710	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_c20720	COG2204	response regulator
MIM_c20780	COG0559	Belongs to the binding-protein-dependent transport system permease family
MIM_c20790	COG0300	oxidoreductase activity
MIM_c20850	COG1012	belongs to the aldehyde dehydrogenase family
MIM_c20860	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c20870	COG1024	Enoyl-CoA hydratase
MIM_c20880	COG1960	acyl-CoA dehydrogenase activity
MIM_c20890	COG1024	Enoyl-CoA hydratase
MIM_c20940	COG0583	DNA-binding transcription factor activity
MIM_c20950	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_c20960	COG1960	acyl-CoA dehydrogenase activity
MIM_c20980	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MIM_c21010	COG0519	Catalyzes the synthesis of GMP from XMP
MIM_c21010	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MIM_c21040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MIM_c21060	COG1764	response to oxidative stress
MIM_c21070	COG0656	L-ascorbic acid biosynthetic process
MIM_c21080	COG0583	DNA-binding transcription factor activity
MIM_c21090	COG0739	heme binding
MIM_c21130	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c21150	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MIM_c21150	COG2111	Na H antiporter
MIM_c21160	COG1006	Multisubunit Na H antiporter MnhC subunit
MIM_c21170	COG0651	ATP synthesis coupled electron transport
MIM_c21190	COG2212	antiporter activity
MIM_c21210	COG0778	Nitroreductase
MIM_c21220	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MIM_c21230	COG1538	Outer membrane efflux protein
MIM_c21240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MIM_c21270	COG4120	Belongs to the binding-protein-dependent transport system permease family
MIM_c21300	COG0183	Belongs to the thiolase family
MIM_c21330	COG1187	pseudouridine synthase activity
MIM_c21340	COG3161	chorismate lyase activity
MIM_c21350	COG0347	Belongs to the P(II) protein family
MIM_c21360	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MIM_c21360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MIM_c21370	COG0165	Argininosuccinate lyase
MIM_c21380	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MIM_c21410	COG4942	peptidase
MIM_c21420	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MIM_c21430	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MIM_c21440	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MIM_c21450	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MIM_c21460	COG2252	PERMEase
MIM_c21470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MIM_c21490	COG0488	(ABC) transporter
MIM_c21500	COG1619	proteins homologs of microcin C7 resistance protein MccF
MIM_c21510	COG0590	tRNA wobble adenosine to inosine editing
MIM_c21530	COG3712	iron ion homeostasis
MIM_c21540	COG1595	DNA-templated transcription, initiation
MIM_c21570	COG2824	Alkylphosphonate utilization operon protein PhnA
MIM_c21620	COG0519	Catalyzes the synthesis of GMP from XMP
MIM_c21620	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MIM_c21650	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MIM_c21650	COG0047	phosphoribosylformylglycinamidine synthase activity
MIM_c21660	COG1686	Belongs to the peptidase S11 family
MIM_c21700	COG0210	DNA helicase
MIM_c21710	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MIM_c21780	COG1304	FMN binding
MIM_c21800	COG0776	regulation of translation
MIM_c21810	COG0072	phenylalanine-tRNA ligase activity
MIM_c21810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MIM_c21820	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MIM_c21830	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MIM_c21840	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MIM_c21890	COG0004	ammonium transporteR
MIM_c21900	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MIM_c21910	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MIM_c21930	COG0189	ligase activity
MIM_c21940	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MIM_c21950	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MIM_c21980	COG3344	reverse transcriptase
MIM_c22000	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MIM_c22010	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MIM_c22020	COG0740	serine-type endopeptidase activity
MIM_c22030	COG0544	peptidyl-prolyl cis-trans isomerase activity
MIM_c22090	COG0410	ABC transporter
MIM_c22100	COG0829	nickel cation binding
MIM_c22130	COG0832	Belongs to the urease beta subunit family
MIM_c22140	COG0804	urea catabolic process
MIM_c22150	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MIM_c22170	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MIM_c22190	COG1760	l-serine dehydratase
MIM_c22210	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MIM_c22220	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MIM_c22260	COG1278	Cold shock
MIM_c22270	COG0542	response to heat
MIM_c22320	COG1126	abc transporter atp-binding protein
MIM_c22330	COG0765	amino acid transport
MIM_c22360	COG2721	sulfolactate sulfo-lyase activity
MIM_c22410	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c22430	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MIM_c22440	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MIM_c22460	COG3237	CsbD-like
MIM_c22510	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MIM_c22550	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MIM_c22640	COG0411	ABC transporter
MIM_c22650	COG0410	ABC transporter
MIM_c22660	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MIM_c22700	COG3278	Belongs to the heme-copper respiratory oxidase family
MIM_c22740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MIM_c22750	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MIM_c22760	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
MIM_c22800	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MIM_c22810	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MIM_c22820	COG0287	Prephenate dehydrogenase
MIM_c22840	COG1605	Chorismate mutase
MIM_c22840	COG0077	Prephenate dehydratase
MIM_c22850	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MIM_c22880	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MIM_c22900	COG2885	chlorophyll binding
MIM_c22930	COG1091	dTDP-4-dehydrorhamnose reductase activity
MIM_c22960	COG0793	Belongs to the peptidase S41A family
MIM_c22970	COG2951	lytic endotransglycosylase activity
MIM_c22990	COG5002	protein histidine kinase activity
MIM_c23000	COG0745	RESPONSE REGULATOR receiver
MIM_c23030	COG2323	membrane
MIM_c23040	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MIM_c23050	COG2732	(Barnase) inhibitor
MIM_c23080	COG2134	cdp-diacylglycerol pyrophosphatase
MIM_c23100	COG0069	glutamate synthase activity
MIM_c23140	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
MIM_c23150	COG3909	cytochrome
MIM_c23170	COG0482	sulfurtransferase activity
MIM_c23180	COG0247	lactate metabolic process
MIM_c23190	COG0277	FAD linked oxidase domain protein
MIM_c23200	COG0277	FAD linked oxidase domain protein
MIM_c23210	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MIM_c23220	COG0312	modulator of DNA gyrase
MIM_c23240	COG0308	aminopeptidase N
MIM_c23250	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
MIM_c23260	COG0667	Aldo Keto reductase
MIM_c23290	COG1846	Transcriptional regulator
MIM_c23300	COG0433	COG0433 Predicted ATPase
MIM_c23310	COG0217	transcriptional regulatory protein
MIM_c23320	COG0151	Belongs to the GarS family
MIM_c23330	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MIM_c23340	COG0799	negative regulation of ribosome biogenesis
MIM_c23350	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MIM_c23360	COG0424	maF-like protein
MIM_c23370	COG0625	glutathione transferase activity
MIM_c23390	COG1047	Peptidyl-prolyl cis-trans
MIM_c23400	COG2003	Belongs to the UPF0758 family
MIM_c23410	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
MIM_c23430	COG3483	tryptophan 2,3-dioxygenase activity
MIM_c23450	COG0254	rRNA binding
MIM_c23480	COG2814	Major facilitator Superfamily
MIM_c23500	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MIM_c23520	COG0583	DNA-binding transcription factor activity
MIM_c23560	COG2363	Small membrane protein
MIM_c23620	COG0791	NLP P60 protein
MIM_c23650	COG1960	acyl-CoA dehydrogenase activity
MIM_c23660	COG0183	Belongs to the thiolase family
MIM_c23670	COG1250	3-hydroxyacyl-CoA dehydrogenase
MIM_c23670	COG1024	Enoyl-CoA hydratase
MIM_c23700	COG0318	PFAM AMP-dependent synthetase and ligase
MIM_c23710	COG0583	DNA-binding transcription factor activity
MIM_c23730	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MIM_c23800	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MIM_c23810	COG0571	ribonuclease III activity
MIM_c23820	COG0681	Belongs to the peptidase S26 family
MIM_c23830	COG0481	GTPase activity
MIM_c23840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MIM_c23890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MIM_c23920	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MIM_c23930	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MIM_c23940	COG0416	fatty acid biosynthetic process
MIM_c23950	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MIM_c23970	COG0424	maF-like protein
MIM_c23990	COG3023	N-Acetylmuramoyl-L-alanine amidase
MIM_c24000	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
MIM_c24010	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MIM_c24030	COG0564	pseudouridine synthase activity
MIM_c24040	COG1530	ribonuclease E activity
MIM_c24080	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MIM_c24090	COG0159	tryptophan synthase activity
MIM_c24100	COG0133	tryptophan synthase activity
MIM_c24110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MIM_c24130	COG0251	oxidation-reduction process
MIM_c24140	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MIM_c24150	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MIM_c24180	COG2878	Part of a membrane complex involved in electron transport
MIM_c24190	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MIM_c24200	COG0410	ABC transporter
MIM_c24210	COG0411	ABC transporter
MIM_c24220	COG0559	Belongs to the binding-protein-dependent transport system permease family
MIM_c24240	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MIM_c24250	COG2917	probably involved in intracellular septation
MIM_c24270	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MIM_c24280	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MIM_c24300	COG1196	nuclear chromosome segregation
MIM_c24310	COG0477	Major facilitator Superfamily
MIM_c24320	COG1573	uracil-dna glycosylase
MIM_c24330	COG1214	PFAM Peptidase M22, glycoprotease
MIM_c24340	COG0745	RESPONSE REGULATOR receiver
MIM_c24350	COG2205	protein histidine kinase activity
MIM_c24360	COG0450	alkyl hydroperoxide reductase
MIM_c24370	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MIM_c24390	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MIM_c24400	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MIM_c24410	COG0560	Phosphoserine phosphatase
MIM_c24440	COG2176	DNA-directed DNA polymerase activity
MIM_c24460	COG1007	ATP synthesis coupled electron transport
MIM_c24490	COG0713	ATP synthesis coupled electron transport
MIM_c24510	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MIM_c24520	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MIM_c24530	COG1034	ATP synthesis coupled electron transport
MIM_c24550	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
MIM_c24560	COG0649	NAD binding
MIM_c24570	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MIM_c24580	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MIM_c24590	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MIM_c24600	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MIM_c24610	COG3344	reverse transcriptase
MIM_c24630	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
MIM_c24650	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MIM_c24660	COG0149	triose-phosphate isomerase activity
MIM_c24680	COG0589	response to stress
MIM_c24690	COG0659	secondary active sulfate transmembrane transporter activity
MIM_c24700	COG2814	Major facilitator Superfamily
MIM_c24770	COG3800	Transcriptional regulator
MIM_c24770	COG1396	sequence-specific DNA binding
MIM_c24780	COG2860	membrane
MIM_c24790	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MIM_c24790	COG1473	amidohydrolase
MIM_c24800	COG0583	DNA-binding transcription factor activity
MIM_c24830	COG1024	Enoyl-CoA hydratase
MIM_c24870	COG4774	siderophore transport
MIM_c24890	COG0625	glutathione transferase activity
MIM_c24900	COG0477	Major facilitator Superfamily
MIM_c24930	COG1960	acyl-CoA dehydrogenase activity
MIM_c24940	COG1024	Enoyl-CoA hydratase
MIM_c24960	COG1024	Enoyl-CoA hydratase
MIM_c24970	COG0318	PFAM AMP-dependent synthetase and ligase
MIM_c25000	COG0183	Belongs to the thiolase family
MIM_c25010	COG1250	3-hydroxyacyl-CoA dehydrogenase
MIM_c25010	COG1024	Enoyl-CoA hydratase
MIM_c25100	COG4106	trans-aconitate 2-methyltransferase activity
MIM_c25120	COG0438	transferase activity, transferring glycosyl groups
MIM_c25150	COG0076	glutamate decarboxylase activity
MIM_c25160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MIM_c25180	COG0583	DNA-binding transcription factor activity
MIM_c25190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIM_c25230	COG0583	DNA-binding transcription factor activity
MIM_c25240	COG1346	cytolysis
MIM_c25250	COG1380	Effector of murein hydrolase LrgA
MIM_c25260	COG0583	DNA-binding transcription factor activity
MIM_c25270	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
MIM_c25320	COG3278	Belongs to the heme-copper respiratory oxidase family
MIM_c25330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MIM_c25350	COG0583	DNA-binding transcription factor activity
MIM_c25360	COG2186	Transcriptional regulator
MIM_c25370	COG0477	Major facilitator Superfamily
MIM_c25380	COG0252	asparaginase activity
MIM_c25400	COG0596	Alpha beta hydrolase
MIM_c25420	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c25440	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c25460	COG3718	enzyme involved in inositol metabolism
MIM_c25470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MIM_c25490	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c25580	COG0671	phosphoesterase, PA-phosphatase related
MIM_c25620	COG4773	Receptor
MIM_c25630	COG0577	efflux transmembrane transporter activity
MIM_c25630	COG1136	(ABC) transporter
MIM_c25640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIM_c25770	COG1404	Belongs to the peptidase S8 family
MIM_c25780	COG0583	DNA-binding transcription factor activity
MIM_c25820	COG3486	L-lysine 6-monooxygenase (NADPH) activity
MIM_c25860	COG3486	L-lysine 6-monooxygenase (NADPH) activity
MIM_c25870	COG4773	Receptor
MIM_c25890	COG0789	Transcriptional regulator
MIM_c25910	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MIM_c25960	COG0248	Ppx GppA phosphatase
MIM_c25980	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MIM_c26000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MIM_c26010	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
MIM_c26020	COG1534	Rna-binding protein
MIM_c26030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MIM_c26040	COG2233	PERMEase
MIM_c26050	COG0406	alpha-ribazole phosphatase activity
MIM_c26060	COG0300	oxidoreductase activity
MIM_c26080	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MIM_c26090	COG0505	Belongs to the CarA family
MIM_c26110	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MIM_c26120	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MIM_c26130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MIM_c26150	COG1074	ATP-dependent DNA helicase activity
MIM_c26230	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MIM_c26240	COG3657	addiction module killer protein
MIM_c26270	COG4974	Belongs to the 'phage' integrase family
MIM_c26290	COG0860	N-Acetylmuramoyl-L-alanine amidase
MIM_c26300	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MIM_c26310	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MIM_c26320	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MIM_c26330	COG0628	permease
MIM_c26340	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MIM_c26360	COG0617	tRNA 3'-terminal CCA addition
MIM_c26380	COG4608	Belongs to the ABC transporter superfamily
MIM_c26390	COG0444	Belongs to the ABC transporter superfamily
MIM_c26400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIM_c26410	COG0601	transmembrane transport
MIM_c26420	COG0747	negative chemotaxis
MIM_c26430	COG0747	negative chemotaxis
MIM_c26440	COG0747	negative chemotaxis
MIM_c26460	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c26470	COG1414	Transcriptional regulator
MIM_c26510	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MIM_c26520	COG0318	PFAM AMP-dependent synthetase and ligase
MIM_c26530	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c26540	COG1673	EVE domain
MIM_c26590	COG1024	Enoyl-CoA hydratase
MIM_c26600	COG0752	glycyl-tRNA synthetase alpha subunit
MIM_c26610	COG0751	glycine-tRNA ligase activity
MIM_c26620	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MIM_c26630	COG0204	Acyl-transferase
MIM_c26650	COG0346	lactoylglutathione lyase activity
MIM_c26670	COG1929	Belongs to the glycerate kinase type-1 family
MIM_c26680	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MIM_c26690	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MIM_c26700	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
MIM_c26720	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MIM_c26740	COG0745	RESPONSE REGULATOR receiver
MIM_c26750	COG2205	protein histidine kinase activity
MIM_c26780	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MIM_c26790	COG0850	regulation of cytokinetic process
MIM_c26800	COG2894	cell division
MIM_c26810	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
MIM_c26820	COG0488	(ABC) transporter
MIM_c26840	COG1215	transferase activity, transferring glycosyl groups
MIM_c26850	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MIM_c26860	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MIM_c26880	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MIM_c26890	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
MIM_c26900	COG0259	pyridoxamine-phosphate oxidase activity
MIM_c26910	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MIM_c26920	COG0579	oxidoreductase
MIM_c26940	COG3539	Fimbrial protein
MIM_c26990	COG1960	acyl-CoA dehydrogenase activity
MIM_c27010	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MIM_c27020	COG0829	nickel cation binding
MIM_c27050	COG0832	Belongs to the urease beta subunit family
MIM_c27060	COG0831	urea catabolic process
MIM_c27070	COG2030	dehydratase
MIM_c27110	COG0765	amino acid transport
MIM_c27120	COG0765	amino acid transport
MIM_c27130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIM_c27140	COG0583	DNA-binding transcription factor activity
MIM_c27190	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MIM_c27250	COG0411	ABC transporter
MIM_c27280	COG3246	L-lysine catabolic process to acetate
MIM_c27290	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MIM_c27310	COG1250	3-hydroxyacyl-CoA dehydrogenase
MIM_c27320	COG3108	Peptidase M15
MIM_c27330	COG2989	Protein conserved in bacteria
MIM_c27340	COG0412	Dienelactone hydrolase
MIM_c27400	COG3836	Belongs to the HpcH HpaI aldolase family
MIM_c27420	COG1380	Effector of murein hydrolase LrgA
MIM_c27430	COG1346	cytolysis
MIM_c27450	COG1490	D-aminoacyl-tRNA deacylase activity
MIM_c27470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MIM_c27480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MIM_c27490	COG1126	abc transporter atp-binding protein
MIM_c27500	COG0765	amino acid transport
MIM_c27510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIM_c27520	COG1396	sequence-specific DNA binding
MIM_c27540	COG2267	carboxylic ester hydrolase activity
MIM_c27570	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c27600	COG1021	2,3-dihydroxybenzoate-AMP ligase
MIM_c27630	COG1309	transcriptional regulator
MIM_c27640	COG1473	amidohydrolase
MIM_c27650	COG1598	PFAM Uncharacterised protein family UPF0150
MIM_c27680	COG0009	L-threonylcarbamoyladenylate synthase
MIM_c27690	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MIM_c27700	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MIM_c27710	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MIM_c27740	COG0521	Mo-molybdopterin cofactor biosynthetic process
MIM_c27750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MIM_c27760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MIM_c27780	COG0126	phosphoglycerate kinase activity
MIM_c27790	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MIM_c27800	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MIM_c27810	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MIM_c27880	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MIM_c27910	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MIM_c27930	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MIM_c27940	COG0343	queuine tRNA-ribosyltransferase activity
MIM_c27950	COG1862	Preprotein translocase
MIM_c27960	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MIM_c27970	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MIM_c27990	COG1702	phosphate starvation-inducible protein PhoH
MIM_c28000	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MIM_c28020	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MIM_c28030	COG0587	DNA-directed DNA polymerase activity
MIM_c28100	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MIM_c28110	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c28120	COG0583	DNA-binding transcription factor activity
MIM_c28160	COG3443	Belongs to the bacterial solute-binding protein 9 family
MIM_c28280	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MIM_c28290	COG2186	Transcriptional regulator
MIM_c28300	COG2721	sulfolactate sulfo-lyase activity
MIM_c28310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MIM_c28330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MIM_c28340	COG0494	nUDIX hydrolase
MIM_c28360	COG4160	amino acid transport
MIM_c28370	COG4215	(ABC) transporter
MIM_c28380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIM_c28390	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MIM_c28400	COG0697	spore germination
MIM_c28430	COG0477	Major facilitator Superfamily
MIM_c28440	COG0678	peroxiredoxin activity
MIM_c28450	COG0315	cyclic pyranopterin monophosphate synthase activity
MIM_c28480	COG0521	Mo-molybdopterin cofactor biosynthetic process
MIM_c28490	COG0303	'Molybdopterin
MIM_c28500	COG0746	molybdenum cofactor guanylyltransferase activity
MIM_c28510	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MIM_c28530	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
MIM_c28550	COG3383	formate dehydrogenase (NAD+) activity
MIM_c28560	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MIM_c28590	COG0745	RESPONSE REGULATOR receiver
MIM_c28610	COG0589	response to stress
MIM_c28650	COG0463	Glycosyl transferase, family 2
MIM_c28660	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MIM_c28680	COG0741	lytic transglycosylase activity
MIM_c28680	COG1388	LysM domain
MIM_c28690	COG2226	methyltransferase
MIM_c28700	COG0328	RNA-DNA hybrid ribonuclease activity
MIM_c28720	COG5507	3-demethylubiquinone-9 3-methyltransferase
MIM_c28770	COG3501	Rhs element vgr protein
MIM_c28800	COG0583	DNA-binding transcription factor activity
MIM_c28810	COG0129	dihydroxy-acid dehydratase activity
MIM_c28820	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c28840	COG1280	lysine exporter protein (LysE YggA)
MIM_c28890	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MIM_c28890	COG0475	glutathione-regulated potassium exporter activity
MIM_c28910	COG0252	asparaginase activity
MIM_c28950	COG1999	signal sequence binding
MIM_c28980	COG0243	molybdopterin cofactor binding
MIM_c28990	COG2837	iron assimilation
MIM_c29010	COG1132	(ABC) transporter
MIM_c29020	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
MIM_c29030	COG4977	sequence-specific DNA binding
MIM_c29040	COG0523	cobalamin synthesis protein
MIM_c29050	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MIM_c29060	COG0735	belongs to the Fur family
MIM_c29070	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
MIM_c29110	COG0330	HflC and HflK could
MIM_c29160	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MIM_c29170	COG3657	addiction module killer protein
MIM_c29200	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MIM_c29200	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MIM_c29210	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MIM_c29220	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MIM_c29230	COG1881	PFAM PEBP family protein
MIM_c29240	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MIM_c29250	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MIM_c29260	COG0316	Belongs to the HesB IscA family
MIM_c29280	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MIM_c29290	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MIM_c29300	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MIM_c29310	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MIM_c29320	COG0312	modulator of DNA gyrase
MIM_c29330	COG3028	Belongs to the UPF0307 family
MIM_c29350	COG0045	succinate-CoA ligase (ADP-forming) activity
MIM_c29350	COG1042	CoA-binding domain protein
MIM_c29350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MIM_c29360	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MIM_c29380	COG0762	integral membrane protein
MIM_c29410	COG2264	protein methyltransferase activity
MIM_c29420	COG0439	Biotin carboxylase
MIM_c29430	COG0511	ligase activity, forming carbon-carbon bonds
MIM_c29440	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MIM_c29450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MIM_c29460	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MIM_c29470	COG3150	esterase
MIM_c29480	COG0557	exoribonuclease II activity
MIM_c29490	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MIM_c29500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MIM_c29520	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MIM_c29550	COG0540	Belongs to the ATCase OTCase family
MIM_c29560	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MIM_c29570	COG1678	Uncharacterized ACR, COG1678
MIM_c29580	COG1773	rubredoxin
MIM_c29590	COG0351	phosphomethylpyrimidine kinase
MIM_c29600	COG0352	thiamine-phosphate diphosphorylase activity
MIM_c29610	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MIM_c29620	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MIM_c29640	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MIM_c29650	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MIM_c29660	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MIM_c29670	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MIM_c29690	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MIM_c29700	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MIM_c29710	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MIM_c29710	COG1648	precorrin-2 dehydrogenase activity
MIM_c29720	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MIM_c29730	COG1858	cytochrome C peroxidase
MIM_c29800	COG0437	4 iron, 4 sulfur cluster binding
MIM_c29810	COG0348	domain, Protein
MIM_c29830	COG1522	sequence-specific DNA binding
MIM_c29850	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MIM_c29910	COG2084	Dehydrogenase
MIM_c29920	COG0494	nUDIX hydrolase
MIM_c29930	COG0442	prolyl-tRNA aminoacylation
MIM_c29940	COG0824	Thioesterase
MIM_c29960	COG0848	biopolymer transport protein
MIM_c29980	COG0823	Involved in the tonB-independent uptake of proteins
MIM_c30020	COG0038	chloride channel
MIM_c30060	COG0586	Pfam SNARE associated Golgi protein
MIM_c30070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIM_c30080	COG1120	ATPase activity
MIM_c30100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIM_c30110	COG0512	Glutamine amidotransferase of anthranilate synthase
MIM_c30110	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MIM_c30130	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MIM_c30140	COG1294	oxidase, subunit
MIM_c30150	COG1271	oxidase subunit
MIM_c30170	COG0583	DNA-binding transcription factor activity
MIM_c30180	COG2814	Major facilitator Superfamily
MIM_c30220	COG0235	Class ii aldolase
MIM_c30260	COG0778	Nitroreductase
MIM_c30260	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
MIM_c30270	COG1846	Transcriptional regulator
MIM_c30300	COG1566	PFAM secretion protein HlyD family protein
MIM_c30350	COG2873	o-acetylhomoserine
MIM_c30410	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MIM_c30410	COG0446	pyridine nucleotide-disulphide oxidoreductase
MIM_c30430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIM_c30440	COG0765	amino acid transport
MIM_c30450	COG0765	amino acid transport
MIM_c30460	COG0165	Argininosuccinate lyase
MIM_c30480	COG1126	abc transporter atp-binding protein
MIM_c30520	COG0477	Major facilitator Superfamily
MIM_c30540	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MIM_c30550	COG4172	Belongs to the ABC transporter superfamily
MIM_c30560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIM_c30570	COG0601	transmembrane transport
MIM_c30580	COG0747	negative chemotaxis
MIM_c30590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MIM_c30600	COG0028	Belongs to the TPP enzyme family
MIM_c30630	COG4176	ABC-type proline glycine betaine transport system permease component
MIM_c30640	COG4175	Glycine betaine
MIM_c30680	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MIM_c30690	COG1802	Transcriptional regulator
MIM_c30700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MIM_c30710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MIM_c30720	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c30740	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c30760	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c30770	COG1012	belongs to the aldehyde dehydrogenase family
MIM_c30780	COG1013	pyruvate-flavodoxin oxidoreductase activity
MIM_c30800	COG0583	DNA-binding transcription factor activity
MIM_c30810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MIM_c30820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIM_c30830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIM_c30840	COG1120	ATPase activity
MIM_c30870	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c30930	COG0288	reversible hydration of carbon dioxide
MIM_c30940	COG0861	Integral membrane protein TerC family
MIM_c30960	COG0019	diaminopimelate decarboxylase activity
MIM_c31070	COG1335	isochorismatase
MIM_c31080	COG2309	aminopeptidase activity
MIM_c31090	COG0596	Alpha beta hydrolase
MIM_c31100	COG2010	Cytochrome c
MIM_c31100	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MIM_c31110	COG2080	2 iron, 2 sulfur cluster binding
MIM_c31120	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MIM_c31120	COG2010	Cytochrome c
MIM_c31130	COG1846	Transcriptional regulator
MIM_c31140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MIM_c31150	COG2271	Major facilitator Superfamily
MIM_c31180	COG1064	alcohol dehydrogenase
MIM_c31210	COG2207	Transcriptional regulator
MIM_c31220	COG0129	dihydroxy-acid dehydratase activity
MIM_c31230	COG2076	Multidrug Resistance protein
MIM_c31250	COG4944	Protein of unknown function (DUF1109)
MIM_c31260	COG1595	DNA-templated transcription, initiation
MIM_c31300	COG3220	belongs to the UPF0276 family
MIM_c31360	COG1396	sequence-specific DNA binding
MIM_c31360	COG3800	Transcriptional regulator
MIM_c31380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_c31440	COG0730	response to heat
MIM_c31450	COG0405	Gamma-glutamyltransferase
MIM_c31460	COG0814	amino acid
MIM_c31480	COG1522	sequence-specific DNA binding
MIM_c31510	COG1966	Carbon starvation protein
MIM_c31520	COG2132	Multicopper oxidase
MIM_c31540	COG1090	epimerase
MIM_c31550	COG1733	regulation of RNA biosynthetic process
MIM_c31560	COG3485	protocatechuate 3,4-dioxygenase
MIM_c31570	COG0252	asparaginase activity
MIM_c31590	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MIM_c31640	COG2814	Major facilitator Superfamily
MIM_c31680	COG0543	2 iron, 2 sulfur cluster binding
MIM_c31690	COG3258	Cytochrome c
MIM_c31700	COG2863	cytochrome
MIM_c31720	COG1902	pentaerythritol trinitrate reductase activity
MIM_c31730	COG1335	isochorismatase
MIM_c31770	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c31780	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c31790	COG4948	Mandelate Racemase Muconate Lactonizing
MIM_c31830	COG0583	DNA-binding transcription factor activity
MIM_c31850	COG0252	asparaginase activity
MIM_c31920	COG0556	nucleotide-excision repair
MIM_c32010	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MIM_c32020	COG0459	protein refolding
MIM_c32070	COG0284	orotidine-5'-phosphate decarboxylase activity
MIM_c32090	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MIM_c32100	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MIM_c32110	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MIM_c32120	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MIM_c32160	COG1960	acyl-CoA dehydrogenase activity
MIM_c32170	COG1024	Enoyl-CoA hydratase
MIM_c32180	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c32240	COG0742	ribosomal rna small subunit methyltransferase
MIM_c32250	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MIM_c32260	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MIM_c32350	COG0848	biopolymer transport protein
MIM_c32360	COG0811	peptide transport
MIM_c32370	COG1629	transport
MIM_c32370	COG4206	TonB-dependent receptor
MIM_c32380	COG1770	oligopeptidase
MIM_c32410	COG0193	aminoacyl-tRNA hydrolase activity
MIM_c32420	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MIM_c32430	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MIM_c32450	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MIM_c32460	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
MIM_c32480	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MIM_c32490	COG0277	FAD linked oxidase domain protein
MIM_c32510	COG0438	transferase activity, transferring glycosyl groups
MIM_c32520	COG0438	transferase activity, transferring glycosyl groups
MIM_c32530	COG0438	transferase activity, transferring glycosyl groups
MIM_c32540	COG0367	asparagine synthase
MIM_c32580	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MIM_c32590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MIM_c32600	COG3344	reverse transcriptase
MIM_c32620	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
MIM_c32630	COG1765	OsmC-like protein
MIM_c32640	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MIM_c32660	COG0410	ABC transporter
MIM_c32670	COG0411	ABC transporter
MIM_c32710	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c32720	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
MIM_c32770	COG4638	Rieske (2fe-2S)
MIM_c32820	COG1511	domain protein
MIM_c32820	COG3264	Mechanosensitive ion channel
MIM_c32830	COG1737	Transcriptional regulator
MIM_c32840	COG3842	ATPase activity
MIM_c32850	COG1175	transmembrane transport
MIM_c32860	COG0395	ABC-type sugar transport system, permease component
MIM_c32870	COG1653	transport
MIM_c32880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MIM_c32890	COG1796	DNA polymerase
MIM_c32890	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MIM_c32900	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MIM_c32900	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MIM_c32910	COG0509	glycine decarboxylation via glycine cleavage system
MIM_c32920	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MIM_c32950	COG2081	HI0933 family
MIM_c32960	COG1982	Orn Lys Arg decarboxylase major
MIM_c32970	COG0717	Belongs to the dCTP deaminase family
MIM_c33000	COG0489	protein tyrosine kinase activity
MIM_c33030	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c33040	COG1902	pentaerythritol trinitrate reductase activity
MIM_c33090	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MIM_c33090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MIM_c33110	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MIM_c33130	COG1652	LysM domain
MIM_c33140	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MIM_c33160	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MIM_c33170	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MIM_c33180	COG3023	N-Acetylmuramoyl-L-alanine amidase
MIM_c33200	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MIM_c33210	COG0583	DNA-binding transcription factor activity
MIM_c33220	COG0326	Molecular chaperone. Has ATPase activity
MIM_c33300	COG5290	Psort location Cytoplasmic, score
MIM_c33350	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MIM_c33390	COG3501	Rhs element vgr protein
MIM_c33420	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c33530	COG3069	C4-dicarboxylate transmembrane transporter activity
MIM_c33550	COG2186	Transcriptional regulator
MIM_c33560	COG0730	response to heat
MIM_c33610	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MIM_c33640	COG0583	DNA-binding transcription factor activity
MIM_c33660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MIM_c33680	COG2814	Major facilitator Superfamily
MIM_c33690	COG0667	Aldo Keto reductase
MIM_c33700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MIM_c33710	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MIM_c33730	COG2207	Transcriptional regulator
MIM_c33750	COG1566	PFAM secretion protein HlyD family protein
MIM_c33890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_c33900	COG1116	anion transmembrane transporter activity
MIM_c33910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MIM_c33950	COG3501	Rhs element vgr protein
MIM_c33990	COG3501	Rhs element vgr protein
MIM_c34010	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c34050	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
MIM_c34060	COG1116	anion transmembrane transporter activity
MIM_c34070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_c34080	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MIM_c34080	COG1116	anion transmembrane transporter activity
MIM_c34090	COG0446	pyridine nucleotide-disulphide oxidoreductase
MIM_c34130	COG1335	isochorismatase
MIM_c34140	COG3119	arylsulfatase activity
MIM_c34150	COG2207	Transcriptional regulator
MIM_c34160	COG1335	isochorismatase
MIM_c34170	COG0154	amidase activity
MIM_c34180	COG1309	transcriptional regulator
MIM_c34190	COG2814	Major facilitator Superfamily
MIM_c34210	COG0596	Alpha beta hydrolase
MIM_c34320	COG3842	ATPase activity
MIM_c34340	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MIM_c34370	COG3177	Filamentation induced by cAMP protein fic
MIM_c34390	COG3135	benzoate transporter
MIM_c34400	COG1024	Enoyl-CoA hydratase
MIM_c34490	COG0596	Alpha beta hydrolase
MIM_c34510	COG0583	DNA-binding transcription factor activity
MIM_c34550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MIM_c34560	COG1176	ABC-type spermidine putrescine transport system, permease component I
MIM_c34570	COG3833	ABC-type maltose transport systems, permease component
MIM_c34580	COG3842	ATPase activity
MIM_c34600	COG3214	Protein conserved in bacteria
MIM_c34620	COG0583	DNA-binding transcription factor activity
MIM_c34640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_c34680	COG3971	2-oxopent-4-enoate hydratase activity
MIM_c34690	COG0179	Fumarylacetoacetate (FAA) hydrolase
MIM_c34730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MIM_c34810	COG3501	Rhs element vgr protein
MIM_c34840	COG1764	response to oxidative stress
MIM_c34860	COG4172	Belongs to the ABC transporter superfamily
MIM_c34870	COG1609	Transcriptional regulator
MIM_c34890	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c34910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIM_c34960	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MIM_c34990	COG0747	negative chemotaxis
MIM_c35010	COG0559	Belongs to the binding-protein-dependent transport system permease family
MIM_c35020	COG0410	ABC transporter
MIM_c35030	COG0411	ABC transporter
MIM_c35070	COG3501	Rhs element vgr protein
MIM_c35100	COG3501	Rhs element vgr protein
MIM_c35120	COG3501	Rhs element vgr protein
MIM_c35150	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIM_c35170	COG3246	L-lysine catabolic process to acetate
MIM_c35280	COG2831	hemolysin activation secretion protein
MIM_c35310	COG3609	addiction module antidote protein, CC2985 family
MIM_c35330	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c35370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_c35380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_c35410	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MIM_c35430	COG0778	Nitroreductase
MIM_c35460	COG4608	Belongs to the ABC transporter superfamily
MIM_c35470	COG0444	Belongs to the ABC transporter superfamily
MIM_c35480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIM_c35510	COG0583	DNA-binding transcription factor activity
MIM_c35560	COG2084	Dehydrogenase
MIM_c35620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIM_c35650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_c35660	COG3501	Rhs element vgr protein
MIM_c35730	COG0745	RESPONSE REGULATOR receiver
MIM_c35740	COG4771	TonB-dependent receptor
MIM_c35750	COG4607	ABC-type enterochelin transport system periplasmic component
MIM_c35760	COG0583	DNA-binding transcription factor activity
MIM_c35770	COG0667	Aldo Keto reductase
MIM_c35790	COG3420	alginic acid biosynthetic process
MIM_c35800	COG3485	protocatechuate 3,4-dioxygenase
MIM_c35810	COG3485	protocatechuate 3,4-dioxygenase
MIM_c35820	COG2271	Major facilitator Superfamily
MIM_c35830	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MIM_c35840	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MIM_c35850	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MIM_c35860	COG1414	Transcriptional regulator
MIM_c35880	COG0583	DNA-binding transcription factor activity
MIM_c35910	COG0066	3-isopropylmalate dehydratase activity
MIM_c35930	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MIM_c35970	COG1840	ABC-type Fe3 transport system, periplasmic component
MIM_c35980	COG1609	Transcriptional regulator
MIM_c36030	COG1309	transcriptional regulator
MIM_c36040	COG0655	NAD(P)H dehydrogenase (quinone) activity
MIM_c36050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIM_c36060	COG4948	Mandelate Racemase Muconate Lactonizing
MIM_c36070	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MIM_c36080	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c36090	COG0318	PFAM AMP-dependent synthetase and ligase
MIM_c36100	COG1024	Enoyl-CoA hydratase
MIM_c36120	COG1414	Transcriptional regulator
MIM_c36130	COG0604	alcohol dehydrogenase
MIM_c36140	COG0159	tryptophan synthase activity
MIM_c36150	COG0133	tryptophan synthase activity
MIM_c36180	COG1335	isochorismatase
MIM_c36200	COG0583	DNA-binding transcription factor activity
MIM_c36210	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MIM_c36290	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
MIM_c36300	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MIM_c36340	COG1525	nuclease
MIM_c36360	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c36370	COG1959	2 iron, 2 sulfur cluster binding
MIM_c36380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MIM_c36380	COG1017	nitric oxide dioxygenase activity
MIM_c36390	COG2860	membrane
MIM_c36400	COG1113	amino acid transport
MIM_c36410	COG0629	single-stranded DNA binding
MIM_c36420	COG0803	Belongs to the bacterial solute-binding protein 9 family
MIM_c36430	COG1115	amino acid carrier protein
MIM_c36440	COG0748	coenzyme F420 binding
MIM_c36500	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
MIM_c36510	COG0477	Major facilitator Superfamily
MIM_c36530	COG1414	Transcriptional regulator
MIM_c36550	COG0523	cobalamin synthesis protein
MIM_c36560	COG1228	amidohydrolase
MIM_c36610	COG1414	Transcriptional regulator
MIM_c36620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MIM_c36630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_c36640	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MIM_c36650	COG4521	taurine ABC transporter
MIM_c36660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIM_c36670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MIM_c36690	COG0446	pyridine nucleotide-disulphide oxidoreductase
MIM_c36740	COG0583	DNA-binding transcription factor activity
MIM_c36760	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MIM_c36770	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MIM_c36790	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c36800	COG4948	Mandelate Racemase Muconate Lactonizing
MIM_c36810	COG2186	Transcriptional regulator
MIM_c36880	COG1252	NADH dehydrogenase
MIM_c36890	COG1960	acyl-CoA dehydrogenase activity
MIM_c36920	COG1607	acyl-coa hydrolase
MIM_c36960	COG4206	TonB-dependent receptor
MIM_c36970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MIM_c36980	COG0492	ferredoxin-NADP+ reductase activity
MIM_c37000	COG0037	tRNA processing
MIM_c37010	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MIM_c37010	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MIM_c37030	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MIM_c37040	COG2890	protein-(glutamine-N5) methyltransferase activity
MIM_c37050	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MIM_c37060	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MIM_c37160	COG2188	Transcriptional regulator
MIM_c37170	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MIM_c37180	COG3395	kinase activity
MIM_c37210	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c37220	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c37240	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c37250	COG0390	transport system, permease component
MIM_c37260	COG4619	ABC transporter
MIM_c37310	COG0281	malic enzyme
MIM_c37310	COG0280	phosphate acetyltransferase
MIM_c37320	COG0583	DNA-binding transcription factor activity
MIM_c37400	COG0534	Mate efflux family protein
MIM_c37410	COG0583	DNA-binding transcription factor activity
MIM_c37450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIM_c37470	COG0765	amino acid transport
MIM_c37480	COG1126	abc transporter atp-binding protein
MIM_c37490	COG0583	DNA-binding transcription factor activity
MIM_c37510	COG2301	Belongs to the HpcH HpaI aldolase family
MIM_c37530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_c37570	COG2188	Transcriptional regulator
MIM_c37580	COG2721	sulfolactate sulfo-lyase activity
MIM_c37590	COG2721	sulfolactate sulfo-lyase activity
MIM_c37600	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c37610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MIM_c37790	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MIM_c37800	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MIM_c37830	COG1596	polysaccharide export
MIM_c37870	COG2610	gluconate transmembrane transporter activity
MIM_c37880	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MIM_c37930	COG1176	ABC-type spermidine putrescine transport system, permease component I
MIM_c37940	COG3842	ATPase activity
MIM_c38000	COG1566	PFAM secretion protein HlyD family protein
MIM_c38010	COG2814	Major facilitator Superfamily
MIM_c38120	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MIM_c38150	COG0028	Belongs to the TPP enzyme family
MIM_c38160	COG0583	DNA-binding transcription factor activity
MIM_c38200	COG0626	cystathionine gamma-synthase activity
MIM_c38220	COG0697	spore germination
MIM_c38230	COG2375	cellular response to nickel ion
MIM_c38240	COG1695	Transcriptional regulator
MIM_c38270	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c38280	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c38310	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c38340	COG1960	acyl-CoA dehydrogenase activity
MIM_c38350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MIM_c38350	COG1042	CoA-binding domain protein
MIM_c38350	COG0045	succinate-CoA ligase (ADP-forming) activity
MIM_c38360	COG1024	Enoyl-CoA hydratase
MIM_c38370	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MIM_c38380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIM_c38390	COG0583	DNA-binding transcription factor activity
MIM_c38410	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c38420	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c38430	COG4993	Dehydrogenase
MIM_c38460	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MIM_c38480	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MIM_c38560	COG0583	DNA-binding transcription factor activity
MIM_c38610	COG2814	Major facilitator Superfamily
MIM_c38630	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MIM_c38650	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MIM_c38660	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MIM_c38670	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MIM_c38690	COG1965	Belongs to the frataxin family
MIM_c38730	COG1116	anion transmembrane transporter activity
MIM_c38740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_c38760	COG1333	cytochrome c biogenesis protein
MIM_c38780	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MIM_c38840	COG0318	PFAM AMP-dependent synthetase and ligase
MIM_c38890	COG4232	protein-disulfide reductase activity
MIM_c38900	COG1324	tolerance protein
MIM_c38910	COG2814	Major facilitator Superfamily
MIM_c38930	COG0203	ribosomal protein L17
MIM_c38940	COG0202	RNA polymerase activity
MIM_c38950	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MIM_c38960	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MIM_c38970	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MIM_c38990	COG0201	protein transport
MIM_c39000	COG0200	Binds to the 23S rRNA
MIM_c39010	COG1841	ribosomal large subunit assembly
MIM_c39020	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MIM_c39030	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MIM_c39040	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MIM_c39050	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MIM_c39060	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MIM_c39070	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MIM_c39080	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MIM_c39090	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MIM_c39110	COG1176	ABC-type spermidine putrescine transport system, permease component I
MIM_c39130	COG3842	ATPase activity
MIM_c39140	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MIM_c39230	COG4993	Dehydrogenase
MIM_c39240	COG1414	Transcriptional regulator
MIM_c39250	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c39280	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c39300	COG0559	Belongs to the binding-protein-dependent transport system permease family
MIM_c39330	COG0411	ABC transporter
MIM_c39340	COG0640	Transcriptional regulator
MIM_c39380	COG3622	Belongs to the hyi family
MIM_c39390	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MIM_c39400	COG0800	Aldolase
MIM_c39410	COG0277	FAD linked oxidase domain protein
MIM_c39420	COG0129	dihydroxy-acid dehydratase activity
MIM_c39430	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MIM_c39440	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MIM_c39450	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MIM_c39460	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c39550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MIM_c39560	COG0800	Aldolase
MIM_c39570	COG3734	2-keto-3-deoxy-galactonokinase
MIM_c39580	COG0277	FAD linked oxidase domain protein
MIM_c39590	COG0277	FAD linked oxidase domain protein
MIM_c39600	COG3128	pkhd-type hydroxylase
MIM_c39610	COG4774	siderophore transport
MIM_c39630	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MIM_c39640	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MIM_c39650	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MIM_c39660	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MIM_c39670	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MIM_c39680	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MIM_c39690	COG0089	rRNA binding
MIM_c39700	COG0088	Forms part of the polypeptide exit tunnel
MIM_c39710	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MIM_c39730	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MIM_c39740	COG1012	belongs to the aldehyde dehydrogenase family
MIM_c39750	COG4154	Belongs to the RbsD FucU family
MIM_c39760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MIM_c39770	COG1172	Belongs to the binding-protein-dependent transport system permease family
MIM_c39810	COG1349	DNA-binding transcription factor activity
MIM_c39880	COG0559	Belongs to the binding-protein-dependent transport system permease family
MIM_c39920	COG2308	Evidence 4 Homologs of previously reported genes of
MIM_c39940	COG2308	Evidence 4 Homologs of previously reported genes of
MIM_c39960	COG1322	Protein conserved in bacteria
MIM_c40020	COG2011	ABC-type metal ion transport system permease component
MIM_c40040	COG0051	transcription antitermination factor activity, RNA binding
MIM_c40050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MIM_c40060	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MIM_c40070	COG0049	tRNA binding
MIM_c40080	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MIM_c40090	COG0745	RESPONSE REGULATOR receiver
MIM_c40110	COG2205	protein histidine kinase activity
MIM_c40110	COG0784	Response regulator, receiver
MIM_c40120	COG2301	Belongs to the HpcH HpaI aldolase family
MIM_c40130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_c40140	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
MIM_c40150	COG0583	DNA-binding transcription factor activity
MIM_c40160	COG1960	acyl-CoA dehydrogenase activity
MIM_c40280	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c40290	COG1802	Transcriptional regulator
MIM_c40310	COG1250	3-hydroxyacyl-CoA dehydrogenase
MIM_c40320	COG3246	L-lysine catabolic process to acetate
MIM_c40330	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c40390	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MIM_c40430	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MIM_c40490	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_c40500	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MIM_c40530	COG0596	Alpha beta hydrolase
MIM_c40540	COG0583	DNA-binding transcription factor activity
MIM_c40550	COG2423	ornithine cyclodeaminase activity
MIM_c40560	COG1522	sequence-specific DNA binding
MIM_c40580	COG2133	pyrroloquinoline quinone binding
MIM_c40590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MIM_c40600	COG3344	reverse transcriptase
MIM_c40620	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MIM_c40630	COG0085	RNA polymerase activity
MIM_c40640	COG0222	ribosome binding
MIM_c40650	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MIM_c40660	COG0081	regulation of translation
MIM_c40670	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MIM_c40690	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MIM_c40710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MIM_c40750	COG1475	DNA binding
MIM_c40760	COG1192	Involved in chromosome partitioning
MIM_c40770	COG0357	Ribosomal RNA small subunit methyltransferase G
MIM_c40780	COG0445	tRNA wobble uridine modification
MIM_c40790	COG0436	Aminotransferase
MIM_c40800	COG0537	adenosine 5'-monophosphoramidase activity
MIM_c40810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MIM_c40820	COG0477	Major facilitator Superfamily
MIM_c40830	COG3180	Ammonia monooxygenase
MIM_c40840	COG0583	DNA-binding transcription factor activity
MIM_c40930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MIM_c40940	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MIM_c40960	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MIM_c41000	COG0842	Transport permease protein
MIM_c41010	COG0842	Transport permease protein
MIM_c41020	COG1131	(ABC) transporter
MIM_c41050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_c41060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MIM_c41070	COG0583	DNA-binding transcription factor activity
MIM_c41110	COG0045	succinate-CoA ligase (ADP-forming) activity
MIM_c41110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MIM_c41110	COG1042	CoA-binding domain protein
MIM_c41120	COG1960	acyl-CoA dehydrogenase activity
MIM_c41140	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_c41150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIM_c41160	COG0583	DNA-binding transcription factor activity
MIM_c41170	COG0706	membrane insertase activity