MIM_c21930 e1e8956fa5bfcb5e8ef2dfb3f53102c5 319 SUPERFAMILY SSF52440 1 126 5.18E-32 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MIM_c21930 e1e8956fa5bfcb5e8ef2dfb3f53102c5 319 Hamap MF_00162 Glutathione synthetase [gshB]. 1 319 147.244 T 12-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 MIM_c21930 e1e8956fa5bfcb5e8ef2dfb3f53102c5 319 Gene3D G3DSA:3.40.50.20 6 118 3.8E-102 T 12-10-2018 MIM_c21930 e1e8956fa5bfcb5e8ef2dfb3f53102c5 319 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 128 301 5.8E-74 T 12-10-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 MIM_c21930 e1e8956fa5bfcb5e8ef2dfb3f53102c5 319 Gene3D G3DSA:3.30.1490.20 141 205 3.8E-102 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MIM_c21930 e1e8956fa5bfcb5e8ef2dfb3f53102c5 319 TIGRFAM TIGR01380 glut_syn: glutathione synthase 1 316 4.9E-122 T 12-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 MIM_c21930 e1e8956fa5bfcb5e8ef2dfb3f53102c5 319 SUPERFAMILY SSF56059 128 315 7.69E-55 T 12-10-2018 MIM_c21930 e1e8956fa5bfcb5e8ef2dfb3f53102c5 319 Gene3D G3DSA:3.30.470.20 119 299 3.8E-102 T 12-10-2018 MIM_c21930 e1e8956fa5bfcb5e8ef2dfb3f53102c5 319 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 1 124 5.7E-38 T 12-10-2018 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 MIM_c14940 9b4e6ca610b43e374929246f0f9aca6f 477 Gene3D G3DSA:3.40.50.1100 109 456 5.2E-135 T 12-10-2018 MIM_c14940 9b4e6ca610b43e374929246f0f9aca6f 477 Pfam PF14821 Threonine synthase N terminus 2 79 6.8E-29 T 12-10-2018 IPR029144 Threonine synthase, N-terminal MIM_c14940 9b4e6ca610b43e374929246f0f9aca6f 477 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 105 340 1.5E-11 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MIM_c14940 9b4e6ca610b43e374929246f0f9aca6f 477 TIGRFAM TIGR00260 thrC: threonine synthase 103 440 2.9E-68 T 12-10-2018 IPR004450 Threonine synthase-like MIM_c14940 9b4e6ca610b43e374929246f0f9aca6f 477 SUPERFAMILY SSF53686 1 473 9.41E-149 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MIM_c14940 9b4e6ca610b43e374929246f0f9aca6f 477 Gene3D G3DSA:3.40.50.1100 98 443 5.2E-135 T 12-10-2018 MIM_c14940 9b4e6ca610b43e374929246f0f9aca6f 477 Gene3D G3DSA:3.90.1380.10 1 90 8.8E-30 T 12-10-2018 IPR037158 Threonine synthase, N-terminal domain superfamily MIM_c28690 d2a99da3953474cc90ca426d482aa900 262 Pfam PF08241 Methyltransferase domain 76 130 7.9E-8 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 MIM_c28690 d2a99da3953474cc90ca426d482aa900 262 Gene3D G3DSA:3.40.50.150 54 195 4.8E-18 T 12-10-2018 MIM_c28690 d2a99da3953474cc90ca426d482aa900 262 SUPERFAMILY SSF53335 75 196 1.28E-15 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c25350 fc7a55b6455da9fd4fb6acf04a1e34f7 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 3.8E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c25350 fc7a55b6455da9fd4fb6acf04a1e34f7 294 Pfam PF03466 LysR substrate binding domain 88 288 7.6E-41 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c25350 fc7a55b6455da9fd4fb6acf04a1e34f7 294 SUPERFAMILY SSF53850 88 291 7.6E-40 T 12-10-2018 MIM_c25350 fc7a55b6455da9fd4fb6acf04a1e34f7 294 SUPERFAMILY SSF46785 3 110 4.3E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c25350 fc7a55b6455da9fd4fb6acf04a1e34f7 294 Gene3D G3DSA:1.10.10.10 1 89 1.5E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c25350 fc7a55b6455da9fd4fb6acf04a1e34f7 294 Gene3D G3DSA:3.40.190.290 90 288 2.4E-58 T 12-10-2018 MIM_c20050 59a15f83d263aafbc9c6adc7429b8a9e 254 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 77 6.3E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c20050 59a15f83d263aafbc9c6adc7429b8a9e 254 Gene3D G3DSA:1.20.120.530 97 242 9.6E-26 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c20050 59a15f83d263aafbc9c6adc7429b8a9e 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 1.1E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c20050 59a15f83d263aafbc9c6adc7429b8a9e 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 1.1E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c20050 59a15f83d263aafbc9c6adc7429b8a9e 254 Pfam PF07729 FCD domain 104 228 2.0E-22 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c20050 59a15f83d263aafbc9c6adc7429b8a9e 254 SMART SM00345 18 77 7.0E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c20050 59a15f83d263aafbc9c6adc7429b8a9e 254 Gene3D G3DSA:1.10.10.10 6 82 4.0E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c20050 59a15f83d263aafbc9c6adc7429b8a9e 254 SUPERFAMILY SSF48008 98 236 2.12E-25 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c20050 59a15f83d263aafbc9c6adc7429b8a9e 254 SUPERFAMILY SSF46785 10 81 4.08E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c20050 59a15f83d263aafbc9c6adc7429b8a9e 254 SMART SM00895 102 229 2.3E-15 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c26560 70dd894fb12a436b7301f6c358467d0b 344 SUPERFAMILY SSF53474 76 339 5.02E-28 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c26560 70dd894fb12a436b7301f6c358467d0b 344 Gene3D G3DSA:3.40.50.1820 19 342 8.3E-93 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c26560 70dd894fb12a436b7301f6c358467d0b 344 Pfam PF00561 alpha/beta hydrolase fold 219 261 4.0E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c29300 643e2a09923f840dd936c530d33e83be 142 SUPERFAMILY SSF52161 1 139 1.57E-59 T 12-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 MIM_c29300 643e2a09923f840dd936c530d33e83be 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 141 4.7E-63 T 12-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c29300 643e2a09923f840dd936c530d33e83be 142 Pfam PF00572 Ribosomal protein L13 15 138 2.1E-55 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MIM_c29300 643e2a09923f840dd936c530d33e83be 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 28.709 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MIM_c29300 643e2a09923f840dd936c530d33e83be 142 Gene3D G3DSA:3.90.1180.10 1 142 1.6E-61 T 12-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 MIM_c29300 643e2a09923f840dd936c530d33e83be 142 PIRSF PIRSF002181 1 142 8.7E-49 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MIM_c22000 048a0a7bf9e95e145538d8890e9a8f53 822 SUPERFAMILY SSF88697 13 204 1.54E-52 T 12-10-2018 IPR015947 PUA-like superfamily MIM_c22000 048a0a7bf9e95e145538d8890e9a8f53 822 SMART SM00382 350 494 9.6E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c22000 048a0a7bf9e95e145538d8890e9a8f53 822 Gene3D G3DSA:3.40.50.300 316 492 1.3E-61 T 12-10-2018 MIM_c22000 048a0a7bf9e95e145538d8890e9a8f53 822 SMART SM00464 13 205 9.0E-76 T 12-10-2018 IPR003111 Lon, substrate-binding domain MIM_c22000 048a0a7bf9e95e145538d8890e9a8f53 822 Gene3D G3DSA:2.30.130.40 10 118 3.4E-37 T 12-10-2018 MIM_c22000 048a0a7bf9e95e145538d8890e9a8f53 822 TIGRFAM TIGR00763 lon: endopeptidase La 15 786 5.1E-299 T 12-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 MIM_c22000 048a0a7bf9e95e145538d8890e9a8f53 822 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 688 707 2.4E-55 T 12-10-2018 MIM_c22000 048a0a7bf9e95e145538d8890e9a8f53 822 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 741 759 2.4E-55 T 12-10-2018 MIM_c22000 048a0a7bf9e95e145538d8890e9a8f53 822 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 610 626 2.4E-55 T 12-10-2018 MIM_c22000 048a0a7bf9e95e145538d8890e9a8f53 822 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 358 377 2.4E-55 T 12-10-2018 MIM_c22000 048a0a7bf9e95e145538d8890e9a8f53 822 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 718 737 2.4E-55 T 12-10-2018 MIM_c22000 048a0a7bf9e95e145538d8890e9a8f53 822 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 691 699 - T 12-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 MIM_c22000 048a0a7bf9e95e145538d8890e9a8f53 822 Gene3D G3DSA:1.10.8.60 493 599 3.4E-28 T 12-10-2018 MIM_c22000 048a0a7bf9e95e145538d8890e9a8f53 822 SUPERFAMILY SSF52540 315 601 3.12E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c22000 048a0a7bf9e95e145538d8890e9a8f53 822 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 585 787 1.0E-94 T 12-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 MIM_c22000 048a0a7bf9e95e145538d8890e9a8f53 822 SUPERFAMILY SSF54211 610 785 5.31E-59 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MIM_c22000 048a0a7bf9e95e145538d8890e9a8f53 822 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 354 491 6.9E-17 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MIM_c22000 048a0a7bf9e95e145538d8890e9a8f53 822 PIRSF PIRSF001174 2 789 0.0 T 12-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 MIM_c22000 048a0a7bf9e95e145538d8890e9a8f53 822 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 14 201 6.6E-43 T 12-10-2018 IPR003111 Lon, substrate-binding domain MIM_c22000 048a0a7bf9e95e145538d8890e9a8f53 822 Hamap MF_01973 Lon protease [lon]. 14 787 70.021 T 12-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 MIM_c22000 048a0a7bf9e95e145538d8890e9a8f53 822 Gene3D G3DSA:3.30.230.10 600 787 2.2E-80 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MIM_c22000 048a0a7bf9e95e145538d8890e9a8f53 822 Gene3D G3DSA:1.20.58.1480 124 248 6.2E-42 T 12-10-2018 MIM_c18840 3f43cea787bcf6f1811edaed0f355d17 231 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c18840 3f43cea787bcf6f1811edaed0f355d17 231 Pfam PF00005 ABC transporter 26 171 1.0E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c18840 3f43cea787bcf6f1811edaed0f355d17 231 SMART SM00382 35 221 5.0E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c18840 3f43cea787bcf6f1811edaed0f355d17 231 Gene3D G3DSA:3.40.50.300 4 229 9.0E-66 T 12-10-2018 MIM_c18840 3f43cea787bcf6f1811edaed0f355d17 231 SUPERFAMILY SSF52540 6 223 1.21E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c00650 df62cc6cac6558238c06fc280af9d423 230 Pfam PF00196 Bacterial regulatory proteins, luxR family 169 223 3.7E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MIM_c00650 df62cc6cac6558238c06fc280af9d423 230 Gene3D G3DSA:3.40.50.2300 8 111 7.6E-14 T 12-10-2018 MIM_c00650 df62cc6cac6558238c06fc280af9d423 230 ProSitePatterns PS00622 LuxR-type HTH domain signature. 184 211 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MIM_c00650 df62cc6cac6558238c06fc280af9d423 230 SMART SM00421 167 224 5.8E-22 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MIM_c00650 df62cc6cac6558238c06fc280af9d423 230 SUPERFAMILY SSF46894 163 229 4.76E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MIM_c00650 df62cc6cac6558238c06fc280af9d423 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 200 1.3E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MIM_c00650 df62cc6cac6558238c06fc280af9d423 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 184 1.3E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MIM_c00650 df62cc6cac6558238c06fc280af9d423 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 200 212 1.3E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MIM_c00650 df62cc6cac6558238c06fc280af9d423 230 Pfam PF00072 Response regulator receiver domain 12 123 2.1E-17 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c00650 df62cc6cac6558238c06fc280af9d423 230 Gene3D G3DSA:1.10.10.10 112 230 2.0E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c00650 df62cc6cac6558238c06fc280af9d423 230 SUPERFAMILY SSF52172 10 136 2.28E-23 T 12-10-2018 IPR011006 CheY-like superfamily MIM_c00650 df62cc6cac6558238c06fc280af9d423 230 SMART SM00448 10 124 4.8E-18 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c13640 4a612a3945b0baaccd707ca3338f3293 149 Gene3D G3DSA:3.30.479.10 1 149 1.8E-33 T 12-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 MIM_c13640 4a612a3945b0baaccd707ca3338f3293 149 SUPERFAMILY SSF55620 1 146 6.67E-38 T 12-10-2018 MIM_c13640 4a612a3945b0baaccd707ca3338f3293 149 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 4 117 6.5E-28 T 12-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 MIM_c13640 4a612a3945b0baaccd707ca3338f3293 149 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 146 2.1E-33 T 12-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 MIM_c16400 0173a52986fa34765427a7cd65db8402 296 Gene3D G3DSA:2.40.50.140 1 58 4.7E-10 T 12-10-2018 MIM_c16400 0173a52986fa34765427a7cd65db8402 296 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 36 287 1.6E-59 T 12-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 MIM_c16400 0173a52986fa34765427a7cd65db8402 296 Gene3D G3DSA:3.40.50.300 59 229 2.9E-36 T 12-10-2018 MIM_c16400 0173a52986fa34765427a7cd65db8402 296 Pfam PF03193 RsgA GTPase 56 229 5.5E-46 T 12-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 MIM_c16400 0173a52986fa34765427a7cd65db8402 296 Hamap MF_01820 Small ribosomal subunit biogenesis GTPase RsgA [rsgA]. 2 294 33.481 T 12-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 MIM_c16400 0173a52986fa34765427a7cd65db8402 296 Gene3D G3DSA:1.10.40.50 230 296 9.8E-21 T 12-10-2018 MIM_c16400 0173a52986fa34765427a7cd65db8402 296 SUPERFAMILY SSF52540 73 289 1.22E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c16400 0173a52986fa34765427a7cd65db8402 296 SUPERFAMILY SSF50249 2 60 1.14E-10 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c29700 d1436060c95961c2cfdbf2c7b8fdc91f 609 PRINTS PR00369 Flavodoxin signature 69 82 1.7E-13 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MIM_c29700 d1436060c95961c2cfdbf2c7b8fdc91f 609 PRINTS PR00369 Flavodoxin signature 149 159 1.7E-13 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MIM_c29700 d1436060c95961c2cfdbf2c7b8fdc91f 609 PRINTS PR00369 Flavodoxin signature 173 192 1.7E-13 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MIM_c29700 d1436060c95961c2cfdbf2c7b8fdc91f 609 PRINTS PR00369 Flavodoxin signature 117 128 1.7E-13 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MIM_c29700 d1436060c95961c2cfdbf2c7b8fdc91f 609 SUPERFAMILY SSF63380 237 456 2.49E-61 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MIM_c29700 d1436060c95961c2cfdbf2c7b8fdc91f 609 Pfam PF00258 Flavodoxin 70 197 2.8E-29 T 12-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 MIM_c29700 d1436060c95961c2cfdbf2c7b8fdc91f 609 PIRSF PIRSF000207 2 609 2.7E-239 T 12-10-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MIM_c29700 d1436060c95961c2cfdbf2c7b8fdc91f 609 TIGRFAM TIGR01931 cysJ: sulfite reductase [NADPH] flavoprotein, alpha-component 9 609 2.3E-241 T 12-10-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MIM_c29700 d1436060c95961c2cfdbf2c7b8fdc91f 609 SUPERFAMILY SSF52343 454 609 3.54E-48 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MIM_c29700 d1436060c95961c2cfdbf2c7b8fdc91f 609 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 558 566 8.5E-24 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MIM_c29700 d1436060c95961c2cfdbf2c7b8fdc91f 609 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 535 551 8.5E-24 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MIM_c29700 d1436060c95961c2cfdbf2c7b8fdc91f 609 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 466 485 8.5E-24 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MIM_c29700 d1436060c95961c2cfdbf2c7b8fdc91f 609 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 504 515 8.5E-24 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MIM_c29700 d1436060c95961c2cfdbf2c7b8fdc91f 609 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 491 500 8.5E-24 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MIM_c29700 d1436060c95961c2cfdbf2c7b8fdc91f 609 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 279 289 8.5E-24 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MIM_c29700 d1436060c95961c2cfdbf2c7b8fdc91f 609 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 396 403 8.5E-24 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MIM_c29700 d1436060c95961c2cfdbf2c7b8fdc91f 609 Gene3D G3DSA:2.40.30.10 241 449 1.4E-67 T 12-10-2018 MIM_c29700 d1436060c95961c2cfdbf2c7b8fdc91f 609 Pfam PF00175 Oxidoreductase NAD-binding domain 467 573 7.3E-20 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MIM_c29700 d1436060c95961c2cfdbf2c7b8fdc91f 609 Gene3D G3DSA:3.40.50.360 57 222 1.2E-45 T 12-10-2018 IPR029039 Flavoprotein-like superfamily MIM_c29700 d1436060c95961c2cfdbf2c7b8fdc91f 609 Gene3D G3DSA:3.40.50.80 455 609 1.8E-56 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MIM_c29700 d1436060c95961c2cfdbf2c7b8fdc91f 609 Gene3D G3DSA:1.20.990.10 289 394 1.4E-67 T 12-10-2018 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily GO:0016491|GO:0055114 MIM_c29700 d1436060c95961c2cfdbf2c7b8fdc91f 609 Pfam PF00667 FAD binding domain 242 432 5.9E-28 T 12-10-2018 IPR003097 Sulfite reductase [NADPH] flavoprotein alpha-component-like, FAD-binding GO:0016491|GO:0055114 MIM_c29700 d1436060c95961c2cfdbf2c7b8fdc91f 609 SUPERFAMILY SSF52218 67 213 3.19E-44 T 12-10-2018 IPR029039 Flavoprotein-like superfamily MIM_c32950 f738e9c26240cab8b7920ad75dcdaa39 400 Pfam PF03486 HI0933-like protein 5 396 1.8E-138 T 12-10-2018 MIM_c32950 f738e9c26240cab8b7920ad75dcdaa39 400 SUPERFAMILY SSF51905 1 398 2.44E-60 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c32950 f738e9c26240cab8b7920ad75dcdaa39 400 Gene3D G3DSA:2.40.30.10 189 343 1.2E-121 T 12-10-2018 MIM_c32950 f738e9c26240cab8b7920ad75dcdaa39 400 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 7 396 1.0E-120 T 12-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like MIM_c32950 f738e9c26240cab8b7920ad75dcdaa39 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 6.3E-6 T 12-10-2018 MIM_c32950 f738e9c26240cab8b7920ad75dcdaa39 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 366 373 6.3E-6 T 12-10-2018 MIM_c32950 f738e9c26240cab8b7920ad75dcdaa39 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.1E-7 T 12-10-2018 MIM_c32950 f738e9c26240cab8b7920ad75dcdaa39 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 351 373 1.1E-7 T 12-10-2018 MIM_c32950 f738e9c26240cab8b7920ad75dcdaa39 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 1.1E-7 T 12-10-2018 MIM_c32950 f738e9c26240cab8b7920ad75dcdaa39 400 Gene3D G3DSA:1.10.8.260 266 326 1.2E-121 T 12-10-2018 IPR023166 HI0933-like insert domain superfamily MIM_c32950 f738e9c26240cab8b7920ad75dcdaa39 400 Gene3D G3DSA:3.50.50.60 8 392 1.2E-121 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c32950 f738e9c26240cab8b7920ad75dcdaa39 400 SUPERFAMILY SSF160996 190 343 2.22E-36 T 12-10-2018 MIM_c12640 0af0a39ca280846fba2365ae8c78e820 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 1.5E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c12640 0af0a39ca280846fba2365ae8c78e820 301 Gene3D G3DSA:3.40.190.10 167 263 2.4E-39 T 12-10-2018 MIM_c12640 0af0a39ca280846fba2365ae8c78e820 301 SUPERFAMILY SSF53850 96 298 8.53E-31 T 12-10-2018 MIM_c12640 0af0a39ca280846fba2365ae8c78e820 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 2.0E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c12640 0af0a39ca280846fba2365ae8c78e820 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 2.0E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c12640 0af0a39ca280846fba2365ae8c78e820 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 2.0E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c12640 0af0a39ca280846fba2365ae8c78e820 301 Gene3D G3DSA:1.10.10.10 9 97 1.4E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c12640 0af0a39ca280846fba2365ae8c78e820 301 SUPERFAMILY SSF46785 5 88 2.04E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c12640 0af0a39ca280846fba2365ae8c78e820 301 Pfam PF03466 LysR substrate binding domain 95 294 5.9E-28 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c12640 0af0a39ca280846fba2365ae8c78e820 301 Gene3D G3DSA:3.40.190.10 105 292 2.4E-39 T 12-10-2018 MIM_c22030 c3c6f14c9816286c801ffbfe0590010b 436 Gene3D G3DSA:3.30.70.1050 1 116 1.4E-31 T 12-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 MIM_c22030 c3c6f14c9816286c801ffbfe0590010b 436 TIGRFAM TIGR00115 tig: trigger factor 11 417 9.4E-130 T 12-10-2018 IPR005215 Trigger factor GO:0015031 MIM_c22030 c3c6f14c9816286c801ffbfe0590010b 436 Gene3D G3DSA:1.10.3120.10 117 422 1.1E-92 T 12-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 MIM_c22030 c3c6f14c9816286c801ffbfe0590010b 436 Gene3D G3DSA:3.10.50.40 151 248 1.1E-92 T 12-10-2018 MIM_c22030 c3c6f14c9816286c801ffbfe0590010b 436 SUPERFAMILY SSF54534 102 242 2.75E-31 T 12-10-2018 MIM_c22030 c3c6f14c9816286c801ffbfe0590010b 436 Hamap MF_00303 Trigger factor [tig]. 1 423 20.432 T 12-10-2018 IPR005215 Trigger factor GO:0015031 MIM_c22030 c3c6f14c9816286c801ffbfe0590010b 436 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 266 417 6.8E-34 T 12-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 MIM_c22030 c3c6f14c9816286c801ffbfe0590010b 436 PIRSF PIRSF003095 1 435 4.3E-123 T 12-10-2018 IPR005215 Trigger factor GO:0015031 MIM_c22030 c3c6f14c9816286c801ffbfe0590010b 436 SUPERFAMILY SSF102735 1 130 3.14E-32 T 12-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 MIM_c22030 c3c6f14c9816286c801ffbfe0590010b 436 SUPERFAMILY SSF109998 250 434 5.62E-45 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily MIM_c22030 c3c6f14c9816286c801ffbfe0590010b 436 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 158 239 3.2E-15 T 12-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain MIM_c22030 c3c6f14c9816286c801ffbfe0590010b 436 Pfam PF05697 Bacterial trigger factor protein (TF) 1 143 8.1E-35 T 12-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 MIM_c18220 e2c74b10ee287cfea7310f1b116d9d1d 359 Gene3D G3DSA:3.30.250.10 278 355 1.2E-27 T 12-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal MIM_c18220 e2c74b10ee287cfea7310f1b116d9d1d 359 SUPERFAMILY SSF52540 15 276 1.62E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c18220 e2c74b10ee287cfea7310f1b116d9d1d 359 PRINTS PR00142 RecA protein signature 219 247 4.4E-84 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MIM_c18220 e2c74b10ee287cfea7310f1b116d9d1d 359 PRINTS PR00142 RecA protein signature 252 281 4.4E-84 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MIM_c18220 e2c74b10ee287cfea7310f1b116d9d1d 359 PRINTS PR00142 RecA protein signature 102 131 4.4E-84 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MIM_c18220 e2c74b10ee287cfea7310f1b116d9d1d 359 PRINTS PR00142 RecA protein signature 136 165 4.4E-84 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MIM_c18220 e2c74b10ee287cfea7310f1b116d9d1d 359 PRINTS PR00142 RecA protein signature 174 203 4.4E-84 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MIM_c18220 e2c74b10ee287cfea7310f1b116d9d1d 359 PRINTS PR00142 RecA protein signature 306 323 4.4E-84 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MIM_c18220 e2c74b10ee287cfea7310f1b116d9d1d 359 SUPERFAMILY SSF54752 277 336 1.57E-21 T 12-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal MIM_c18220 e2c74b10ee287cfea7310f1b116d9d1d 359 Hamap MF_00268 Protein RecA [recA]. 13 338 51.73 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MIM_c18220 e2c74b10ee287cfea7310f1b116d9d1d 359 Gene3D G3DSA:3.40.50.300 34 277 2.4E-84 T 12-10-2018 MIM_c18220 e2c74b10ee287cfea7310f1b116d9d1d 359 SMART SM00382 66 237 6.0E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c18220 e2c74b10ee287cfea7310f1b116d9d1d 359 ProSitePatterns PS00321 recA signature. 222 230 - T 12-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 MIM_c18220 e2c74b10ee287cfea7310f1b116d9d1d 359 Pfam PF00154 recA bacterial DNA recombination protein 15 277 2.3E-145 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MIM_c18220 e2c74b10ee287cfea7310f1b116d9d1d 359 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 12 333 5.7E-172 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MIM_c01530 466f7faef01eaa50a884631a93f88bab 255 Pfam PF00005 ABC transporter 25 161 7.6E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c01530 466f7faef01eaa50a884631a93f88bab 255 Gene3D G3DSA:3.40.50.300 1 225 1.5E-63 T 12-10-2018 MIM_c01530 466f7faef01eaa50a884631a93f88bab 255 SUPERFAMILY SSF52540 10 214 3.25E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c01530 466f7faef01eaa50a884631a93f88bab 255 SMART SM00382 34 211 2.4E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c01530 466f7faef01eaa50a884631a93f88bab 255 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c03110 b2612c54f25f00c482f61f1d0dc118f8 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 123 306 2.3E-33 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c03110 b2612c54f25f00c482f61f1d0dc118f8 308 Gene3D G3DSA:1.10.3720.10 95 302 3.2E-29 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c03110 b2612c54f25f00c482f61f1d0dc118f8 308 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 20 75 2.9E-9 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MIM_c03110 b2612c54f25f00c482f61f1d0dc118f8 308 SUPERFAMILY SSF161098 100 293 5.36E-30 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c03630 bab38563e3095b6ca47d421575fd6f1a 546 SUPERFAMILY SSF111326 5 543 4.84E-224 T 12-10-2018 IPR036190 Urocanase superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MIM_c03630 bab38563e3095b6ca47d421575fd6f1a 546 Pfam PF17391 Urocanase N-terminal domain 9 129 6.1E-45 T 12-10-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MIM_c03630 bab38563e3095b6ca47d421575fd6f1a 546 Hamap MF_00577 Urocanate hydratase [hutU]. 1 545 43.707 T 12-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MIM_c03630 bab38563e3095b6ca47d421575fd6f1a 546 Pfam PF01175 Urocanase Rossmann-like domain 132 340 1.5E-79 T 12-10-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MIM_c03630 bab38563e3095b6ca47d421575fd6f1a 546 Gene3D G3DSA:3.40.1770.10 10 533 1.3E-221 T 12-10-2018 MIM_c03630 bab38563e3095b6ca47d421575fd6f1a 546 Gene3D G3DSA:3.40.50.10730 133 340 1.3E-221 T 12-10-2018 IPR038364 Urocanase, central domain superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MIM_c03630 bab38563e3095b6ca47d421575fd6f1a 546 Pfam PF17392 Urocanase C-terminal domain 343 536 2.3E-78 T 12-10-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MIM_c03630 bab38563e3095b6ca47d421575fd6f1a 546 TIGRFAM TIGR01228 hutU: urocanate hydratase 7 542 2.3E-217 T 12-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MIM_c03630 bab38563e3095b6ca47d421575fd6f1a 546 PIRSF PIRSF001423 1 546 1.1E-247 T 12-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MIM_c19180 e6d84e8ad23e428292ffc1a6043c59e5 201 SUPERFAMILY SSF46894 137 199 1.5E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MIM_c19180 e6d84e8ad23e428292ffc1a6043c59e5 201 Gene3D G3DSA:3.40.50.2300 2 134 8.4E-48 T 12-10-2018 MIM_c19180 e6d84e8ad23e428292ffc1a6043c59e5 201 SUPERFAMILY SSF52172 8 155 6.26E-35 T 12-10-2018 IPR011006 CheY-like superfamily MIM_c19180 e6d84e8ad23e428292ffc1a6043c59e5 201 Pfam PF00072 Response regulator receiver domain 8 117 4.5E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c19180 e6d84e8ad23e428292ffc1a6043c59e5 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 186 2.2E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MIM_c19180 e6d84e8ad23e428292ffc1a6043c59e5 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 174 2.2E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MIM_c19180 e6d84e8ad23e428292ffc1a6043c59e5 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 144 158 2.2E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MIM_c19180 e6d84e8ad23e428292ffc1a6043c59e5 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 143 197 3.9E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MIM_c19180 e6d84e8ad23e428292ffc1a6043c59e5 201 SMART SM00448 6 117 5.7E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c19180 e6d84e8ad23e428292ffc1a6043c59e5 201 Gene3D G3DSA:1.10.10.10 135 201 5.1E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c19180 e6d84e8ad23e428292ffc1a6043c59e5 201 SMART SM00421 141 198 8.3E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MIM_c19180 e6d84e8ad23e428292ffc1a6043c59e5 201 ProSitePatterns PS00622 LuxR-type HTH domain signature. 158 185 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MIM_c18960 a7f63463793452fdddafd101a6cd3115 521 Pfam PF02954 Bacterial regulatory protein, Fis family 478 516 4.8E-11 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MIM_c18960 a7f63463793452fdddafd101a6cd3115 521 Gene3D G3DSA:1.10.10.60 437 519 6.2E-20 T 12-10-2018 MIM_c18960 a7f63463793452fdddafd101a6cd3115 521 Gene3D G3DSA:3.40.50.2300 1 122 1.4E-38 T 12-10-2018 MIM_c18960 a7f63463793452fdddafd101a6cd3115 521 Gene3D G3DSA:1.10.8.60 317 395 7.2E-20 T 12-10-2018 MIM_c18960 a7f63463793452fdddafd101a6cd3115 521 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 499 519 5.4E-7 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MIM_c18960 a7f63463793452fdddafd101a6cd3115 521 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 482 499 5.4E-7 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MIM_c18960 a7f63463793452fdddafd101a6cd3115 521 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 4 394 1.0E-180 T 12-10-2018 IPR010114 DNA-binding transcriptional regulator NtrC GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 MIM_c18960 a7f63463793452fdddafd101a6cd3115 521 SUPERFAMILY SSF46689 443 519 2.73E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c18960 a7f63463793452fdddafd101a6cd3115 521 SUPERFAMILY SSF52540 150 389 3.7E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c18960 a7f63463793452fdddafd101a6cd3115 521 SMART SM00448 2 113 2.5E-33 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c18960 a7f63463793452fdddafd101a6cd3115 521 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 170 183 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MIM_c18960 a7f63463793452fdddafd101a6cd3115 521 SMART SM00382 166 309 1.5E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c18960 a7f63463793452fdddafd101a6cd3115 521 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 232 247 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MIM_c18960 a7f63463793452fdddafd101a6cd3115 521 Pfam PF00072 Response regulator receiver domain 4 113 1.2E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c18960 a7f63463793452fdddafd101a6cd3115 521 SUPERFAMILY SSF52172 1 190 2.99E-42 T 12-10-2018 IPR011006 CheY-like superfamily MIM_c18960 a7f63463793452fdddafd101a6cd3115 521 Pfam PF00158 Sigma-54 interaction domain 149 312 2.1E-68 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MIM_c18960 a7f63463793452fdddafd101a6cd3115 521 Gene3D G3DSA:3.40.50.300 137 316 1.1E-62 T 12-10-2018 MIM_c18960 a7f63463793452fdddafd101a6cd3115 521 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 359 368 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site MIM_c40140 a67a483bec5a2b18f7dc9727c037e624 279 Gene3D G3DSA:3.10.129.10 165 279 4.2E-15 T 12-10-2018 MIM_c40140 a67a483bec5a2b18f7dc9727c037e624 279 Gene3D G3DSA:3.10.129.10 17 156 3.1E-9 T 12-10-2018 MIM_c40140 a67a483bec5a2b18f7dc9727c037e624 279 SUPERFAMILY SSF54637 77 150 7.93E-5 T 12-10-2018 IPR029069 HotDog domain superfamily MIM_c40140 a67a483bec5a2b18f7dc9727c037e624 279 SUPERFAMILY SSF54637 166 278 3.96E-18 T 12-10-2018 IPR029069 HotDog domain superfamily MIM_c40140 a67a483bec5a2b18f7dc9727c037e624 279 Pfam PF13452 N-terminal half of MaoC dehydratase 76 139 6.1E-9 T 12-10-2018 IPR039569 N-terminal of MaoC-like dehydratase Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-9033241|Reactome: R-HSA-9033500 MIM_c24970 3247da4feb2fd5f8ba3526eb9be1b0ed 633 Pfam PF13193 AMP-binding enzyme C-terminal domain 482 557 5.2E-15 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MIM_c24970 3247da4feb2fd5f8ba3526eb9be1b0ed 633 Gene3D G3DSA:3.40.50.12780 32 465 2.4E-80 T 12-10-2018 MIM_c24970 3247da4feb2fd5f8ba3526eb9be1b0ed 633 Gene3D G3DSA:3.30.300.30 466 570 1.9E-26 T 12-10-2018 MIM_c24970 3247da4feb2fd5f8ba3526eb9be1b0ed 633 ProSitePatterns PS00455 Putative AMP-binding domain signature. 218 229 - T 12-10-2018 IPR020845 AMP-binding, conserved site MIM_c24970 3247da4feb2fd5f8ba3526eb9be1b0ed 633 SUPERFAMILY SSF56801 30 566 1.83E-113 T 12-10-2018 MIM_c24970 3247da4feb2fd5f8ba3526eb9be1b0ed 633 Pfam PF00501 AMP-binding enzyme 47 472 8.2E-70 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MIM_c25970 b4798189a05e3357ff5c73e745f89398 254 SUPERFAMILY SSF55729 23 226 1.16E-33 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c25970 b4798189a05e3357ff5c73e745f89398 254 Pfam PF13444 Acetyltransferase (GNAT) domain 36 137 7.9E-30 T 12-10-2018 MIM_c25970 b4798189a05e3357ff5c73e745f89398 254 Gene3D G3DSA:3.40.630.30 22 178 5.2E-24 T 12-10-2018 MIM_c15540 22fd38bbb670e8f3fd5bbdf86820b783 524 Pfam PF03471 Transporter associated domain 430 512 1.3E-16 T 12-10-2018 IPR005170 Transporter-associated domain MIM_c15540 22fd38bbb670e8f3fd5bbdf86820b783 524 SUPERFAMILY SSF56176 426 519 7.36E-16 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MIM_c15540 22fd38bbb670e8f3fd5bbdf86820b783 524 Pfam PF03741 Integral membrane protein TerC family 14 203 2.2E-47 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 MIM_c15540 22fd38bbb670e8f3fd5bbdf86820b783 524 Gene3D G3DSA:3.10.580.10 279 429 9.4E-46 T 12-10-2018 MIM_c15540 22fd38bbb670e8f3fd5bbdf86820b783 524 Pfam PF00571 CBS domain 367 416 1.7E-5 T 12-10-2018 IPR000644 CBS domain MIM_c15540 22fd38bbb670e8f3fd5bbdf86820b783 524 SUPERFAMILY SSF54631 286 419 5.98E-19 T 12-10-2018 MIM_c15540 22fd38bbb670e8f3fd5bbdf86820b783 524 Gene3D G3DSA:3.30.465.10 430 513 1.1E-13 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MIM_c15540 22fd38bbb670e8f3fd5bbdf86820b783 524 SMART SM01091 429 514 1.5E-17 T 12-10-2018 IPR005170 Transporter-associated domain MIM_c04720 495921c3af86e72c192af19f0f395de1 457 SMART SM00490 253 334 5.9E-25 T 12-10-2018 IPR001650 Helicase, C-terminal MIM_c04720 495921c3af86e72c192af19f0f395de1 457 Gene3D G3DSA:3.40.50.300 1 206 1.0E-72 T 12-10-2018 MIM_c04720 495921c3af86e72c192af19f0f395de1 457 Gene3D G3DSA:3.40.50.300 213 373 1.4E-41 T 12-10-2018 MIM_c04720 495921c3af86e72c192af19f0f395de1 457 Pfam PF00271 Helicase conserved C-terminal domain 231 333 1.4E-24 T 12-10-2018 IPR001650 Helicase, C-terminal MIM_c04720 495921c3af86e72c192af19f0f395de1 457 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 12-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MIM_c04720 495921c3af86e72c192af19f0f395de1 457 SUPERFAMILY SSF52540 69 356 4.66E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c04720 495921c3af86e72c192af19f0f395de1 457 SMART SM00487 20 217 4.1E-59 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MIM_c04720 495921c3af86e72c192af19f0f395de1 457 Gene3D G3DSA:3.30.70.330 383 455 2.6E-19 T 12-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily MIM_c04720 495921c3af86e72c192af19f0f395de1 457 Pfam PF03880 DbpA RNA binding domain 384 454 2.0E-21 T 12-10-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain MIM_c04720 495921c3af86e72c192af19f0f395de1 457 Pfam PF00270 DEAD/DEAH box helicase 25 188 1.1E-48 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MIM_c10610 20e5a01e6ff49e59862daa6cfdc44a35 181 Gene3D G3DSA:3.10.420.10 12 170 9.9E-6 T 12-10-2018 IPR035958 SecB-like superfamily MIM_c10610 20e5a01e6ff49e59862daa6cfdc44a35 181 SUPERFAMILY SSF54611 39 151 6.1E-10 T 12-10-2018 IPR035958 SecB-like superfamily MIM_c22680 128640ed7906bee0b9ebcdbe02ce711a 300 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 132 206 2.2E-11 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c22680 128640ed7906bee0b9ebcdbe02ce711a 300 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 219 294 1.9E-14 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c22680 128640ed7906bee0b9ebcdbe02ce711a 300 SUPERFAMILY SSF46626 61 211 5.67E-30 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c22680 128640ed7906bee0b9ebcdbe02ce711a 300 Pfam PF14715 N-terminal domain of cytochrome oxidase-cbb3, FixP 42 88 5.2E-18 T 12-10-2018 IPR032858 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal MIM_c22680 128640ed7906bee0b9ebcdbe02ce711a 300 PIRSF PIRSF000006 5 300 1.7E-96 T 12-10-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III MIM_c22680 128640ed7906bee0b9ebcdbe02ce711a 300 PRINTS PR00605 Class IC cytochrome C signature 142 153 7.0E-6 T 12-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 MIM_c22680 128640ed7906bee0b9ebcdbe02ce711a 300 PRINTS PR00605 Class IC cytochrome C signature 272 294 7.0E-6 T 12-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 MIM_c22680 128640ed7906bee0b9ebcdbe02ce711a 300 Gene3D G3DSA:1.20.58.1490 5 99 2.4E-24 T 12-10-2018 IPR038414 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal domain superfamily MIM_c22680 128640ed7906bee0b9ebcdbe02ce711a 300 SUPERFAMILY SSF46626 213 299 8.27E-25 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c22680 128640ed7906bee0b9ebcdbe02ce711a 300 Gene3D G3DSA:1.10.760.10 109 297 1.3E-71 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c22680 128640ed7906bee0b9ebcdbe02ce711a 300 TIGRFAM TIGR00782 ccoP: cytochrome c oxidase, cbb3-type, subunit III 41 300 7.7E-73 T 12-10-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III MIM_c22680 128640ed7906bee0b9ebcdbe02ce711a 300 Gene3D G3DSA:1.10.760.10 187 274 1.3E-71 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c07830 7769348bc33c69a7775cfbe5abe0c808 99 Pfam PF04221 RelB antitoxin 5 53 2.2E-13 T 12-10-2018 IPR007337 RelB antitoxin/Antitoxin DinJ MIM_c07830 7769348bc33c69a7775cfbe5abe0c808 99 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 3 56 1.6E-14 T 12-10-2018 IPR007337 RelB antitoxin/Antitoxin DinJ MIM_c07830 7769348bc33c69a7775cfbe5abe0c808 99 Gene3D G3DSA:1.10.1220.10 5 87 1.6E-11 T 12-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 MIM_c06710 5feb7ce83db7b34f79fec1d88b7525e7 461 SUPERFAMILY SSF53756 75 459 5.76E-14 T 12-10-2018 MIM_c06710 5feb7ce83db7b34f79fec1d88b7525e7 461 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 57 229 2.3E-54 T 12-10-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 MIM_c06710 5feb7ce83db7b34f79fec1d88b7525e7 461 Gene3D G3DSA:3.40.50.2000 235 443 6.5E-56 T 12-10-2018 MIM_c06710 5feb7ce83db7b34f79fec1d88b7525e7 461 Gene3D G3DSA:3.40.50.11720 56 228 2.6E-43 T 12-10-2018 IPR038107 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal domain superfamily KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 MIM_c06710 5feb7ce83db7b34f79fec1d88b7525e7 461 Pfam PF00534 Glycosyl transferases group 1 341 441 5.9E-7 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 Gene3D G3DSA:3.50.50.60 148 474 9.0E-119 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 168 7.7E-39 T 12-10-2018 MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 434 456 7.7E-39 T 12-10-2018 MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 405 421 7.7E-39 T 12-10-2018 MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 279 297 7.7E-39 T 12-10-2018 MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 317 335 7.7E-39 T 12-10-2018 MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 PIRSF PIRSF000350 68 607 2.0E-84 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 182 192 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 147 602 9.8E-147 T 12-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 Gene3D G3DSA:3.50.50.60 294 415 9.0E-119 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 SUPERFAMILY SSF51230 2 95 1.7E-22 T 12-10-2018 IPR011053 Single hybrid motif MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 Gene3D G3DSA:3.30.390.30 487 608 1.1E-46 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 SUPERFAMILY SSF55424 484 607 8.93E-40 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 148 469 3.9E-59 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 488 596 1.4E-34 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 Gene3D G3DSA:2.40.50.100 3 80 3.4E-20 T 12-10-2018 MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 SUPERFAMILY SSF51905 144 479 4.26E-55 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 449 456 2.6E-68 T 12-10-2018 MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 148 170 2.6E-68 T 12-10-2018 MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 181 196 2.6E-68 T 12-10-2018 MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 571 591 2.6E-68 T 12-10-2018 MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 420 2.6E-68 T 12-10-2018 MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 282 291 2.6E-68 T 12-10-2018 MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 317 342 2.6E-68 T 12-10-2018 MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 484 505 2.6E-68 T 12-10-2018 MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 549 564 2.6E-68 T 12-10-2018 MIM_c19220 5e08c828e9b5af3605cb0e683bf3a956 613 Pfam PF00364 Biotin-requiring enzyme 5 76 7.3E-21 T 12-10-2018 IPR000089 Biotin/lipoyl attachment MIM_c37180 72aaf15c8a99562fec788921af111275 404 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 237 391 3.2E-20 T 12-10-2018 IPR031475 Four-carbon acid sugar kinase, C-terminal domain MIM_c37180 72aaf15c8a99562fec788921af111275 404 Gene3D G3DSA:3.40.980.20 229 400 4.1E-18 T 12-10-2018 MIM_c37180 72aaf15c8a99562fec788921af111275 404 Gene3D G3DSA:3.40.50.10840 4 228 4.9E-54 T 12-10-2018 IPR037051 Four-carbon acid sugar kinase, N-terminal domain superfamily MIM_c37180 72aaf15c8a99562fec788921af111275 404 SUPERFAMILY SSF142764 5 398 1.07E-82 T 12-10-2018 MIM_c37180 72aaf15c8a99562fec788921af111275 404 Pfam PF07005 Putative sugar-binding N-terminal domain 5 221 2.9E-45 T 12-10-2018 IPR010737 Four-carbon acid sugar kinase, N-terminal domain MIM_c00350 61b8e6c2b2f0c134f82d7f0424e42592 227 Gene3D G3DSA:3.50.30.100 1 196 4.3E-55 T 12-10-2018 MIM_c00350 61b8e6c2b2f0c134f82d7f0424e42592 227 SUPERFAMILY SSF89562 27 185 6.02E-47 T 12-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily MIM_c00350 61b8e6c2b2f0c134f82d7f0424e42592 227 Pfam PF03737 Aldolase/RraA 30 173 5.5E-42 T 12-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MIM_c11810 92c11d242154b38dd5ff22d924b1c97b 243 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 40 243 25.095 T 12-10-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 MIM_c11810 92c11d242154b38dd5ff22d924b1c97b 243 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 71 233 3.2E-41 T 12-10-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like MIM_c11810 92c11d242154b38dd5ff22d924b1c97b 243 SUPERFAMILY SSF89392 60 242 3.37E-40 T 12-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX MIM_c11810 92c11d242154b38dd5ff22d924b1c97b 243 Gene3D G3DSA:2.50.20.10 60 242 2.5E-48 T 12-10-2018 MIM_c11810 92c11d242154b38dd5ff22d924b1c97b 243 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 53 239 1.3E-20 T 12-10-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 MIM_c40960 18b2089bf71c202de48f20253d134761 212 Gene3D G3DSA:3.40.50.360 1 205 3.2E-42 T 12-10-2018 IPR029039 Flavoprotein-like superfamily MIM_c40960 18b2089bf71c202de48f20253d134761 212 SUPERFAMILY SSF52218 1 205 2.26E-37 T 12-10-2018 IPR029039 Flavoprotein-like superfamily MIM_c40960 18b2089bf71c202de48f20253d134761 212 Pfam PF02525 Flavodoxin-like fold 1 200 1.6E-36 T 12-10-2018 IPR003680 Flavodoxin-like fold MIM_c40960 18b2089bf71c202de48f20253d134761 212 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 203 23.649 T 12-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 MIM_c06850 2687ddb49d5a0260c21a9666b9da6f6f 344 SUPERFAMILY SSF51735 2 335 6.35E-74 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c06850 2687ddb49d5a0260c21a9666b9da6f6f 344 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 2 336 8.6E-140 T 12-10-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 MIM_c06850 2687ddb49d5a0260c21a9666b9da6f6f 344 Gene3D G3DSA:3.90.25.10 187 335 2.9E-144 T 12-10-2018 MIM_c06850 2687ddb49d5a0260c21a9666b9da6f6f 344 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 2 340 52.087 T 12-10-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 MIM_c06850 2687ddb49d5a0260c21a9666b9da6f6f 344 Gene3D G3DSA:3.40.50.720 4 321 2.9E-144 T 12-10-2018 MIM_c06850 2687ddb49d5a0260c21a9666b9da6f6f 344 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 330 1.7E-133 T 12-10-2018 IPR016040 NAD(P)-binding domain MIM_c26010 b865fd027a94243cca2220e39d0dc06b 217 PIRSF PIRSF005461 1 216 3.6E-69 T 12-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 MIM_c26010 b865fd027a94243cca2220e39d0dc06b 217 SUPERFAMILY SSF53335 27 210 2.02E-34 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c26010 b865fd027a94243cca2220e39d0dc06b 217 Pfam PF01728 FtsJ-like methyltransferase 28 208 2.6E-51 T 12-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 MIM_c26010 b865fd027a94243cca2220e39d0dc06b 217 Gene3D G3DSA:3.40.50.150 27 215 2.5E-54 T 12-10-2018 MIM_c26010 b865fd027a94243cca2220e39d0dc06b 217 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 12 210 29.507 T 12-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 MIM_c40590 c92b515869852a0f249af34211491605 409 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 118 294 6.4E-53 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MIM_c40590 c92b515869852a0f249af34211491605 409 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 200 222 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MIM_c40590 c92b515869852a0f249af34211491605 409 SUPERFAMILY SSF51735 108 295 9.05E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c40590 c92b515869852a0f249af34211491605 409 Gene3D G3DSA:3.40.50.720 15 312 9.1E-108 T 12-10-2018 MIM_c40590 c92b515869852a0f249af34211491605 409 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 154 181 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 MIM_c40590 c92b515869852a0f249af34211491605 409 Gene3D G3DSA:3.30.70.260 328 408 9.4E-30 T 12-10-2018 MIM_c40590 c92b515869852a0f249af34211491605 409 SUPERFAMILY SSF55021 337 408 3.51E-15 T 12-10-2018 MIM_c40590 c92b515869852a0f249af34211491605 409 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 13 326 1.2E-36 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 MIM_c40590 c92b515869852a0f249af34211491605 409 SUPERFAMILY SSF52283 7 136 1.12E-47 T 12-10-2018 MIM_c40590 c92b515869852a0f249af34211491605 409 Gene3D G3DSA:3.40.50.720 109 297 9.1E-108 T 12-10-2018 MIM_c34470 d2810a96829b68a05be341a8fabea505 321 PIRSF PIRSF017082 1 321 6.9E-72 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c34470 d2810a96829b68a05be341a8fabea505 321 Gene3D G3DSA:3.40.190.10 122 246 2.0E-88 T 12-10-2018 MIM_c34470 d2810a96829b68a05be341a8fabea505 321 Gene3D G3DSA:3.40.190.150 26 311 2.0E-88 T 12-10-2018 MIM_c34470 d2810a96829b68a05be341a8fabea505 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 316 1.3E-67 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c34470 d2810a96829b68a05be341a8fabea505 321 SUPERFAMILY SSF53850 110 279 4.71E-12 T 12-10-2018 MIM_c17480 92a7846afab5bdd8252d05dd21dfdfc5 162 TIGRFAM TIGR02337 HpaR: homoprotocatechuate degradation operon regulator, HpaR 19 148 7.2E-41 T 12-10-2018 IPR012712 Homoprotocatechuate degradation transcriptional regulator HpaR GO:0003677|GO:0010124|GO:0045892 MIM_c17480 92a7846afab5bdd8252d05dd21dfdfc5 162 Pfam PF12802 MarR family 43 102 3.6E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c17480 92a7846afab5bdd8252d05dd21dfdfc5 162 Gene3D G3DSA:1.10.10.10 1 153 2.4E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c17480 92a7846afab5bdd8252d05dd21dfdfc5 162 SUPERFAMILY SSF46785 15 152 4.36E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c17480 92a7846afab5bdd8252d05dd21dfdfc5 162 SMART SM00347 37 138 8.5E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c17480 92a7846afab5bdd8252d05dd21dfdfc5 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 98 114 1.2E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c17480 92a7846afab5bdd8252d05dd21dfdfc5 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 128 148 1.2E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c17480 92a7846afab5bdd8252d05dd21dfdfc5 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 78 1.2E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c17480 92a7846afab5bdd8252d05dd21dfdfc5 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 79 94 1.2E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c18370 81b252701f2dbf4fbef67af37652ffb9 231 Gene3D G3DSA:3.90.850.10 1 231 9.5E-83 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MIM_c18370 81b252701f2dbf4fbef67af37652ffb9 231 SUPERFAMILY SSF56529 20 231 4.58E-69 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MIM_c18370 81b252701f2dbf4fbef67af37652ffb9 231 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 27 230 1.0E-51 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 MIM_c08430 8c9830d239c5e18c065dbef20fa6b50e 294 Pfam PF03466 LysR substrate binding domain 91 291 2.4E-38 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c08430 8c9830d239c5e18c065dbef20fa6b50e 294 SUPERFAMILY SSF46785 4 86 6.8E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c08430 8c9830d239c5e18c065dbef20fa6b50e 294 SUPERFAMILY SSF53850 92 293 1.19E-39 T 12-10-2018 MIM_c08430 8c9830d239c5e18c065dbef20fa6b50e 294 Gene3D G3DSA:1.10.10.10 3 94 4.5E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c08430 8c9830d239c5e18c065dbef20fa6b50e 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 1.2E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c08430 8c9830d239c5e18c065dbef20fa6b50e 294 Gene3D G3DSA:3.40.190.290 95 294 2.5E-40 T 12-10-2018 MIM_c08430 8c9830d239c5e18c065dbef20fa6b50e 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.5E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c08430 8c9830d239c5e18c065dbef20fa6b50e 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.5E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c08430 8c9830d239c5e18c065dbef20fa6b50e 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.5E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c08930 062809a4335a17428c5ff385b196e5c9 297 SUPERFAMILY SSF46785 6 88 9.05E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c08930 062809a4335a17428c5ff385b196e5c9 297 Pfam PF03466 LysR substrate binding domain 88 291 4.2E-43 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c08930 062809a4335a17428c5ff385b196e5c9 297 Gene3D G3DSA:1.10.10.10 3 88 3.9E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c08930 062809a4335a17428c5ff385b196e5c9 297 Gene3D G3DSA:3.40.190.290 91 290 5.7E-55 T 12-10-2018 MIM_c08930 062809a4335a17428c5ff385b196e5c9 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 3.1E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c08930 062809a4335a17428c5ff385b196e5c9 297 SUPERFAMILY SSF53850 89 294 3.44E-43 T 12-10-2018 MIM_c33800 390ac2f4931d56566fda7f528f58bbb1 353 Pfam PF00805 Pentapeptide repeats (8 copies) 279 315 7.8E-9 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c33800 390ac2f4931d56566fda7f528f58bbb1 353 Pfam PF13599 Pentapeptide repeats (9 copies) 104 196 8.4E-8 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c33800 390ac2f4931d56566fda7f528f58bbb1 353 Pfam PF13599 Pentapeptide repeats (9 copies) 200 276 1.1E-9 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c33800 390ac2f4931d56566fda7f528f58bbb1 353 Pfam PF13599 Pentapeptide repeats (9 copies) 32 102 3.0E-12 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c33800 390ac2f4931d56566fda7f528f58bbb1 353 Gene3D G3DSA:2.160.20.100 151 322 3.0E-36 T 12-10-2018 MIM_c33800 390ac2f4931d56566fda7f528f58bbb1 353 Gene3D G3DSA:2.160.20.100 4 150 4.8E-29 T 12-10-2018 MIM_c33800 390ac2f4931d56566fda7f528f58bbb1 353 SUPERFAMILY SSF141571 155 312 4.02E-36 T 12-10-2018 MIM_c33800 390ac2f4931d56566fda7f528f58bbb1 353 SUPERFAMILY SSF141571 17 161 9.71E-30 T 12-10-2018 MIM_c00230 110882033b5020d72ca935a6b8bad097 335 Gene3D G3DSA:3.40.190.10 34 310 6.1E-63 T 12-10-2018 MIM_c00230 110882033b5020d72ca935a6b8bad097 335 Gene3D G3DSA:3.40.190.10 107 209 6.1E-63 T 12-10-2018 MIM_c00230 110882033b5020d72ca935a6b8bad097 335 SUPERFAMILY SSF53850 46 259 1.4E-32 T 12-10-2018 MIM_c00230 110882033b5020d72ca935a6b8bad097 335 Pfam PF09084 NMT1/THI5 like 70 253 2.2E-13 T 12-10-2018 IPR015168 SsuA/THI5-like MIM_c39500 1ac14ed593085fa8d7e3c02387574c82 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 319 2.5E-52 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c39500 1ac14ed593085fa8d7e3c02387574c82 322 Gene3D G3DSA:3.40.190.150 27 313 6.4E-86 T 12-10-2018 MIM_c39500 1ac14ed593085fa8d7e3c02387574c82 322 SUPERFAMILY SSF53850 112 287 1.3E-8 T 12-10-2018 MIM_c39500 1ac14ed593085fa8d7e3c02387574c82 322 PIRSF PIRSF017082 2 322 4.4E-92 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c39500 1ac14ed593085fa8d7e3c02387574c82 322 Gene3D G3DSA:3.40.190.10 122 248 6.4E-86 T 12-10-2018 MIM_c13330 57f8ffdfb8a5450923988fecb5ef61db 958 Pfam PF02779 Transketolase, pyrimidine binding domain 602 800 2.5E-66 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MIM_c13330 57f8ffdfb8a5450923988fecb5ef61db 958 SUPERFAMILY SSF52518 586 807 1.28E-49 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c13330 57f8ffdfb8a5450923988fecb5ef61db 958 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 805 947 2.2E-50 T 12-10-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MIM_c13330 57f8ffdfb8a5450923988fecb5ef61db 958 Gene3D G3DSA:3.40.50.11610 737 944 1.7E-170 T 12-10-2018 MIM_c13330 57f8ffdfb8a5450923988fecb5ef61db 958 Gene3D G3DSA:3.40.50.970 175 537 1.3E-144 T 12-10-2018 MIM_c13330 57f8ffdfb8a5450923988fecb5ef61db 958 PIRSF PIRSF000157 1 949 0.0 T 12-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MIM_c13330 57f8ffdfb8a5450923988fecb5ef61db 958 Gene3D G3DSA:1.10.287.1150 91 174 4.3E-24 T 12-10-2018 MIM_c13330 57f8ffdfb8a5450923988fecb5ef61db 958 Gene3D G3DSA:3.40.50.12470 566 816 1.7E-170 T 12-10-2018 MIM_c13330 57f8ffdfb8a5450923988fecb5ef61db 958 SMART SM00861 603 800 7.6E-61 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MIM_c13330 57f8ffdfb8a5450923988fecb5ef61db 958 SUPERFAMILY SSF52518 128 553 6.48E-89 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c13330 57f8ffdfb8a5450923988fecb5ef61db 958 Pfam PF00676 Dehydrogenase E1 component 223 531 9.4E-48 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 MIM_c13330 57f8ffdfb8a5450923988fecb5ef61db 958 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 13 946 0.0 T 12-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MIM_c13330 57f8ffdfb8a5450923988fecb5ef61db 958 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 10 48 6.6E-16 T 12-10-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MIM_c12660 f7660160572a8b54105eedbcff4de004 457 Pfam PF07690 Major Facilitator Superfamily 30 392 7.8E-44 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c12660 f7660160572a8b54105eedbcff4de004 457 Gene3D G3DSA:1.20.1250.20 11 437 2.0E-76 T 12-10-2018 MIM_c12660 f7660160572a8b54105eedbcff4de004 457 SUPERFAMILY SSF103473 17 429 6.54E-78 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c07870 9007ee14af431ce2083f77412a485654 376 SMART SM00922 149 247 4.4E-25 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MIM_c07870 9007ee14af431ce2083f77412a485654 376 SUPERFAMILY SSF51604 115 367 3.28E-70 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MIM_c07870 9007ee14af431ce2083f77412a485654 376 SUPERFAMILY SSF54826 4 127 6.34E-29 T 12-10-2018 MIM_c07870 9007ee14af431ce2083f77412a485654 376 Gene3D G3DSA:3.20.20.120 126 360 7.1E-72 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MIM_c07870 9007ee14af431ce2083f77412a485654 376 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 11 127 4.1E-20 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain MIM_c07870 9007ee14af431ce2083f77412a485654 376 Pfam PF13378 Enolase C-terminal domain-like 153 362 6.8E-60 T 12-10-2018 IPR029065 Enolase C-terminal domain-like MIM_c07870 9007ee14af431ce2083f77412a485654 376 Gene3D G3DSA:3.30.390.10 2 125 9.0E-32 T 12-10-2018 IPR029017 Enolase-like, N-terminal MIM_c24400 b1f97e26df58739541ecee21d6a9180e 1145 SMART SM00490 824 908 1.8E-18 T 12-10-2018 IPR001650 Helicase, C-terminal MIM_c24400 b1f97e26df58739541ecee21d6a9180e 1145 Pfam PF03461 TRCF domain 1007 1098 1.4E-24 T 12-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 MIM_c24400 b1f97e26df58739541ecee21d6a9180e 1145 Gene3D G3DSA:3.40.50.300 476 988 3.5E-228 T 12-10-2018 MIM_c24400 b1f97e26df58739541ecee21d6a9180e 1145 Gene3D G3DSA:2.30.30.840 481 539 3.5E-228 T 12-10-2018 MIM_c24400 b1f97e26df58739541ecee21d6a9180e 1145 Gene3D G3DSA:3.40.50.11140 349 448 4.6E-14 T 12-10-2018 MIM_c24400 b1f97e26df58739541ecee21d6a9180e 1145 SUPERFAMILY SSF52540 781 988 1.1E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c24400 b1f97e26df58739541ecee21d6a9180e 1145 SUPERFAMILY SSF143517 992 1144 4.71E-37 T 12-10-2018 IPR037235 TRCF-like, C-terminal domain MIM_c24400 b1f97e26df58739541ecee21d6a9180e 1145 SUPERFAMILY SSF52540 347 461 3.36E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c24400 b1f97e26df58739541ecee21d6a9180e 1145 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 33 1107 27.025 T 12-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 MIM_c24400 b1f97e26df58739541ecee21d6a9180e 1145 Pfam PF00271 Helicase conserved C-terminal domain 805 907 5.3E-18 T 12-10-2018 IPR001650 Helicase, C-terminal MIM_c24400 b1f97e26df58739541ecee21d6a9180e 1145 SUPERFAMILY SSF141259 469 546 5.75E-22 T 12-10-2018 IPR036101 CarD-like/TRCF domain superfamily MIM_c24400 b1f97e26df58739541ecee21d6a9180e 1145 Gene3D G3DSA:3.40.50.300 540 779 3.5E-228 T 12-10-2018 MIM_c24400 b1f97e26df58739541ecee21d6a9180e 1145 SUPERFAMILY SSF52540 13 347 1.38E-95 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c24400 b1f97e26df58739541ecee21d6a9180e 1145 Gene3D G3DSA:3.90.1150.50 1003 1145 1.6E-36 T 12-10-2018 IPR037235 TRCF-like, C-terminal domain MIM_c24400 b1f97e26df58739541ecee21d6a9180e 1145 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 149 1079 0.0 T 12-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 MIM_c24400 b1f97e26df58739541ecee21d6a9180e 1145 SUPERFAMILY SSF52540 521 781 2.2E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c24400 b1f97e26df58739541ecee21d6a9180e 1145 SMART SM01058 477 574 1.7E-44 T 12-10-2018 IPR003711 CarD-like/TRCF domain MIM_c24400 b1f97e26df58739541ecee21d6a9180e 1145 Gene3D G3DSA:3.40.50.11180 26 336 4.0E-112 T 12-10-2018 MIM_c24400 b1f97e26df58739541ecee21d6a9180e 1145 Pfam PF02559 CarD-like/TRCF domain 478 573 1.4E-23 T 12-10-2018 IPR003711 CarD-like/TRCF domain MIM_c24400 b1f97e26df58739541ecee21d6a9180e 1145 Gene3D G3DSA:3.30.2060.10 131 216 4.0E-112 T 12-10-2018 MIM_c24400 b1f97e26df58739541ecee21d6a9180e 1145 Pfam PF00270 DEAD/DEAH box helicase 603 760 3.9E-17 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MIM_c24400 b1f97e26df58739541ecee21d6a9180e 1145 SMART SM00982 1006 1106 9.2E-43 T 12-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 MIM_c24400 b1f97e26df58739541ecee21d6a9180e 1145 SMART SM00487 598 788 6.1E-33 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MIM_c01000 11a6699d068cce0bbb7c121df03ee35e 337 PIRSF PIRSF006470 4 334 7.9E-68 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 MIM_c01000 11a6699d068cce0bbb7c121df03ee35e 337 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 38 310 5.3E-68 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 MIM_c01000 11a6699d068cce0bbb7c121df03ee35e 337 Gene3D G3DSA:3.40.190.170 29 337 7.8E-100 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily MIM_c01000 11a6699d068cce0bbb7c121df03ee35e 337 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 39 280 4.9E-63 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 MIM_c02890 d38ae8b02a73e3652025fa23de8b84e2 724 SUPERFAMILY SSF51645 2 721 9.81E-301 T 12-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MIM_c02890 d38ae8b02a73e3652025fa23de8b84e2 724 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 5 720 0.0 T 12-10-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MIM_c02890 d38ae8b02a73e3652025fa23de8b84e2 724 Gene3D G3DSA:1.20.1220.12 581 724 1.3E-72 T 12-10-2018 MIM_c02890 d38ae8b02a73e3652025fa23de8b84e2 724 Gene3D G3DSA:2.170.170.11 135 264 5.7E-278 T 12-10-2018 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MIM_c02890 d38ae8b02a73e3652025fa23de8b84e2 724 Gene3D G3DSA:3.20.20.360 10 580 5.7E-278 T 12-10-2018 MIM_c02890 d38ae8b02a73e3652025fa23de8b84e2 724 Hamap MF_00641 Malate synthase G [glcB]. 1 724 395.296 T 12-10-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MIM_c02890 d38ae8b02a73e3652025fa23de8b84e2 724 Pfam PF01274 Malate synthase 18 682 5.2E-174 T 12-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MIM_c06610 e3aded3c7193749dfc646b5955cd265f 101 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 2 52 1.4E-21 T 12-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain MIM_c06610 e3aded3c7193749dfc646b5955cd265f 101 SMART SM00834 2 42 2.1E-15 T 12-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain MIM_c06610 e3aded3c7193749dfc646b5955cd265f 101 Pfam PF09723 Zinc ribbon domain 2 41 1.3E-15 T 12-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain MIM_c06890 459e921119a4693617db69bf1218807f 406 SUPERFAMILY SSF52540 33 234 1.63E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c06890 459e921119a4693617db69bf1218807f 406 Pfam PF14524 Wzt C-terminal domain 260 398 3.1E-35 T 12-10-2018 IPR029439 Wzt, C-terminal MIM_c06890 459e921119a4693617db69bf1218807f 406 Gene3D G3DSA:3.40.50.300 2 250 2.6E-44 T 12-10-2018 MIM_c06890 459e921119a4693617db69bf1218807f 406 SMART SM00382 50 230 4.8E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c06890 459e921119a4693617db69bf1218807f 406 Pfam PF00005 ABC transporter 41 173 3.2E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c06890 459e921119a4693617db69bf1218807f 406 Gene3D G3DSA:2.70.50.60 251 394 1.8E-15 T 12-10-2018 MIM_c06890 459e921119a4693617db69bf1218807f 406 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c23360 dd6c7da8153911b719d1db4514d21e95 203 Pfam PF02545 Maf-like protein 9 196 1.4E-48 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 MIM_c23360 dd6c7da8153911b719d1db4514d21e95 203 SUPERFAMILY SSF52972 6 195 6.02E-52 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MIM_c23360 dd6c7da8153911b719d1db4514d21e95 203 TIGRFAM TIGR00172 maf: septum formation protein Maf 7 195 7.5E-41 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 MIM_c23360 dd6c7da8153911b719d1db4514d21e95 203 Gene3D G3DSA:3.90.950.10 4 200 3.3E-59 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MIM_c23360 dd6c7da8153911b719d1db4514d21e95 203 Hamap MF_00528 Septum formation protein Maf [maf]. 8 202 26.377 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 MIM_c23360 dd6c7da8153911b719d1db4514d21e95 203 PIRSF PIRSF006305 1 202 9.3E-47 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 MIM_c24530 71e6551ee9ef0f89787ea3cbe286a6f9 775 Gene3D G3DSA:3.30.70.20 127 205 1.5E-7 T 12-10-2018 MIM_c24530 71e6551ee9ef0f89787ea3cbe286a6f9 775 Gene3D G3DSA:3.40.50.740 456 656 7.1E-15 T 12-10-2018 MIM_c24530 71e6551ee9ef0f89787ea3cbe286a6f9 775 Gene3D G3DSA:3.40.50.740 282 346 2.6E-15 T 12-10-2018 MIM_c24530 71e6551ee9ef0f89787ea3cbe286a6f9 775 SUPERFAMILY SSF54862 76 211 3.64E-36 T 12-10-2018 MIM_c24530 71e6551ee9ef0f89787ea3cbe286a6f9 775 SUPERFAMILY SSF53706 214 646 3.5E-74 T 12-10-2018 MIM_c24530 71e6551ee9ef0f89787ea3cbe286a6f9 775 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 4 625 5.7E-200 T 12-10-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24530 71e6551ee9ef0f89787ea3cbe286a6f9 775 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 83 122 1.9E-17 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24530 71e6551ee9ef0f89787ea3cbe286a6f9 775 SUPERFAMILY SSF54292 1 74 1.64E-20 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MIM_c24530 71e6551ee9ef0f89787ea3cbe286a6f9 775 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 98 110 - T 12-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24530 71e6551ee9ef0f89787ea3cbe286a6f9 775 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 12-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24530 71e6551ee9ef0f89787ea3cbe286a6f9 775 SUPERFAMILY SSF50692 695 762 3.06E-7 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily MIM_c24530 71e6551ee9ef0f89787ea3cbe286a6f9 775 Gene3D G3DSA:3.40.228.10 347 409 2.6E-15 T 12-10-2018 MIM_c24530 71e6551ee9ef0f89787ea3cbe286a6f9 775 Pfam PF00384 Molybdopterin oxidoreductase 534 625 2.0E-8 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24530 71e6551ee9ef0f89787ea3cbe286a6f9 775 Pfam PF00384 Molybdopterin oxidoreductase 273 413 2.0E-17 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24530 71e6551ee9ef0f89787ea3cbe286a6f9 775 Gene3D G3DSA:3.10.20.740 1 123 6.2E-41 T 12-10-2018 MIM_c24530 71e6551ee9ef0f89787ea3cbe286a6f9 775 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 146 156 - T 12-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24530 71e6551ee9ef0f89787ea3cbe286a6f9 775 Pfam PF01568 Molydopterin dinucleotide binding domain 692 760 6.2E-8 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 MIM_c24530 71e6551ee9ef0f89787ea3cbe286a6f9 775 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 1 74 3.4E-20 T 12-10-2018 MIM_c24530 71e6551ee9ef0f89787ea3cbe286a6f9 775 Gene3D G3DSA:2.40.40.20 683 773 1.9E-6 T 12-10-2018 MIM_c24530 71e6551ee9ef0f89787ea3cbe286a6f9 775 SMART SM00929 83 123 3.5E-21 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c26310 560c8d82bf3334a0b0d6407a5cda7bad 310 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 5 306 27.439 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 MIM_c26310 560c8d82bf3334a0b0d6407a5cda7bad 310 Gene3D G3DSA:1.10.20.140 112 183 5.0E-92 T 12-10-2018 MIM_c26310 560c8d82bf3334a0b0d6407a5cda7bad 310 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 7 291 1.4E-89 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 MIM_c26310 560c8d82bf3334a0b0d6407a5cda7bad 310 SUPERFAMILY SSF52540 7 146 8.54E-17 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c26310 560c8d82bf3334a0b0d6407a5cda7bad 310 SUPERFAMILY SSF52540 5 267 1.3E-5 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c26310 560c8d82bf3334a0b0d6407a5cda7bad 310 Pfam PF01715 IPP transferase 39 285 4.2E-80 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 MIM_c26310 560c8d82bf3334a0b0d6407a5cda7bad 310 Gene3D G3DSA:3.40.50.300 9 289 5.0E-92 T 12-10-2018 MIM_c23920 fef281c35c81c6344d359505cb54720e 310 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6 305 1.2E-30 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain MIM_c23920 fef281c35c81c6344d359505cb54720e 310 Gene3D G3DSA:3.40.366.10 4 282 7.9E-94 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 MIM_c23920 fef281c35c81c6344d359505cb54720e 310 SUPERFAMILY SSF52151 2 292 4.88E-69 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase MIM_c23920 fef281c35c81c6344d359505cb54720e 310 PIRSF PIRSF000446 1 309 2.7E-104 T 12-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 MIM_c23920 fef281c35c81c6344d359505cb54720e 310 Pfam PF00698 Acyl transferase domain 5 279 1.1E-37 T 12-10-2018 IPR014043 Acyl transferase MIM_c23920 fef281c35c81c6344d359505cb54720e 310 Gene3D G3DSA:3.30.70.250 123 195 7.9E-94 T 12-10-2018 MIM_c23920 fef281c35c81c6344d359505cb54720e 310 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 1 289 3.1E-103 T 12-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 MIM_c23920 fef281c35c81c6344d359505cb54720e 310 SUPERFAMILY SSF55048 126 195 2.09E-17 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding MIM_c35920 0a1d6b5b7667306cb11eaf7dbc2caa91 168 Gene3D G3DSA:1.20.120.450 1 168 4.2E-63 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MIM_c35920 0a1d6b5b7667306cb11eaf7dbc2caa91 168 Pfam PF08020 Protein of unknown function (DUF1706) 3 167 3.1E-51 T 12-10-2018 IPR012550 Protein of unknown function DUF1706 MIM_c25950 e903e329ee08666eecf690251cf7847f 701 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 19 695 6.8E-277 T 12-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MIM_c25950 e903e329ee08666eecf690251cf7847f 701 Hamap MF_00347 Polyphosphate kinase [ppk]. 16 699 27.197 T 12-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MIM_c25950 e903e329ee08666eecf690251cf7847f 701 PIRSF PIRSF015589 2 701 4.8E-255 T 12-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MIM_c25950 e903e329ee08666eecf690251cf7847f 701 SUPERFAMILY SSF140356 17 120 3.01E-32 T 12-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 MIM_c25950 e903e329ee08666eecf690251cf7847f 701 SUPERFAMILY SSF56024 343 510 1.1E-54 T 12-10-2018 MIM_c25950 e903e329ee08666eecf690251cf7847f 701 SUPERFAMILY SSF143724 124 322 5.69E-58 T 12-10-2018 MIM_c25950 e903e329ee08666eecf690251cf7847f 701 Gene3D G3DSA:3.30.870.10 338 517 1.6E-70 T 12-10-2018 MIM_c25950 e903e329ee08666eecf690251cf7847f 701 Pfam PF13090 Polyphosphate kinase C-terminal domain 348 694 6.0E-150 T 12-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 MIM_c25950 e903e329ee08666eecf690251cf7847f 701 Gene3D G3DSA:3.30.1840.10 14 325 1.5E-92 T 12-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 MIM_c25950 e903e329ee08666eecf690251cf7847f 701 SUPERFAMILY SSF56024 519 697 1.57E-66 T 12-10-2018 MIM_c25950 e903e329ee08666eecf690251cf7847f 701 Pfam PF02503 Polyphosphate kinase middle domain 136 335 8.3E-55 T 12-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 MIM_c25950 e903e329ee08666eecf690251cf7847f 701 Pfam PF13089 Polyphosphate kinase N-terminal domain 20 124 5.0E-32 T 12-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 MIM_c25950 e903e329ee08666eecf690251cf7847f 701 Gene3D G3DSA:3.30.870.10 518 699 1.9E-63 T 12-10-2018 MIM_c39530 e69eeb7c2178355a1a447fd58a3af441 131 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 9 120 7.9E-8 T 12-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MIM_c39530 e69eeb7c2178355a1a447fd58a3af441 131 Gene3D G3DSA:3.30.2310.20 2 122 1.3E-6 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MIM_c32380 ee4589bf4b8a6ed2a07d92e450334492 685 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 532 552 5.9E-36 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MIM_c32380 ee4589bf4b8a6ed2a07d92e450334492 685 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 590 605 5.9E-36 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MIM_c32380 ee4589bf4b8a6ed2a07d92e450334492 685 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 503 522 5.9E-36 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MIM_c32380 ee4589bf4b8a6ed2a07d92e450334492 685 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 449 467 5.9E-36 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MIM_c32380 ee4589bf4b8a6ed2a07d92e450334492 685 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 608 630 5.9E-36 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MIM_c32380 ee4589bf4b8a6ed2a07d92e450334492 685 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 475 499 5.9E-36 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MIM_c32380 ee4589bf4b8a6ed2a07d92e450334492 685 Gene3D G3DSA:3.40.50.1820 35 662 1.5E-110 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c32380 ee4589bf4b8a6ed2a07d92e450334492 685 Pfam PF00326 Prolyl oligopeptidase family 472 666 7.6E-44 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 MIM_c32380 ee4589bf4b8a6ed2a07d92e450334492 685 SUPERFAMILY SSF53474 417 658 1.96E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c32380 ee4589bf4b8a6ed2a07d92e450334492 685 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 43 405 3.1E-17 T 12-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 MIM_c32380 ee4589bf4b8a6ed2a07d92e450334492 685 Gene3D G3DSA:2.130.10.120 72 411 1.5E-110 T 12-10-2018 MIM_c32380 ee4589bf4b8a6ed2a07d92e450334492 685 SUPERFAMILY SSF50993 41 406 1.23E-21 T 12-10-2018 MIM_c06560 ab85d46a71d1a12fd2622eee72056f3d 403 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 50 329 8.3E-57 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 MIM_c06560 ab85d46a71d1a12fd2622eee72056f3d 403 Gene3D G3DSA:3.40.190.170 34 347 1.0E-92 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily MIM_c35800 61a7dc67d3f624ff8a2cb6e6df9e473b 209 TIGRFAM TIGR02423 protocat_alph: protocatechuate 3,4-dioxygenase, alpha subunit 12 209 4.6E-84 T 12-10-2018 IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit GO:0005506|GO:0018578|GO:0019439|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3|MetaCyc: PWY-6041 MIM_c35800 61a7dc67d3f624ff8a2cb6e6df9e473b 209 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 55 83 - T 12-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 MIM_c35800 61a7dc67d3f624ff8a2cb6e6df9e473b 209 SUPERFAMILY SSF49482 7 209 1.1E-60 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 MIM_c35800 61a7dc67d3f624ff8a2cb6e6df9e473b 209 Gene3D G3DSA:2.60.130.10 1 209 3.2E-84 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 MIM_c35800 61a7dc67d3f624ff8a2cb6e6df9e473b 209 Pfam PF00775 Dioxygenase 45 199 4.7E-18 T 12-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 MIM_c26030 3d441427afef08766ec88a9f0d3cabf4 158 SUPERFAMILY SSF54534 83 157 1.23E-22 T 12-10-2018 MIM_c26030 3d441427afef08766ec88a9f0d3cabf4 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 12-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 MIM_c26030 3d441427afef08766ec88a9f0d3cabf4 158 PIRSF PIRSF006092 1 158 8.4E-53 T 12-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 MIM_c26030 3d441427afef08766ec88a9f0d3cabf4 158 Pfam PF03449 Transcription elongation factor, N-terminal 4 74 6.3E-32 T 12-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 MIM_c26030 3d441427afef08766ec88a9f0d3cabf4 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 121 137 - T 12-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 MIM_c26030 3d441427afef08766ec88a9f0d3cabf4 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 156 32.579 T 12-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 MIM_c26030 3d441427afef08766ec88a9f0d3cabf4 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 83 157 1.2E-27 T 12-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MIM_c26030 3d441427afef08766ec88a9f0d3cabf4 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 156 1.5E-56 T 12-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 MIM_c26030 3d441427afef08766ec88a9f0d3cabf4 158 Gene3D G3DSA:1.10.287.180 1 75 4.0E-31 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 MIM_c26030 3d441427afef08766ec88a9f0d3cabf4 158 SUPERFAMILY SSF46557 4 77 3.4E-28 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 MIM_c26030 3d441427afef08766ec88a9f0d3cabf4 158 Gene3D G3DSA:3.10.50.30 79 158 9.5E-28 T 12-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 MIM_c16320 cf84cc9bbf5f36ab8693b460bd9b4d92 294 Pfam PF03466 LysR substrate binding domain 88 287 7.4E-31 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c16320 cf84cc9bbf5f36ab8693b460bd9b4d92 294 Gene3D G3DSA:3.40.190.10 89 284 4.3E-45 T 12-10-2018 MIM_c16320 cf84cc9bbf5f36ab8693b460bd9b4d92 294 Gene3D G3DSA:3.40.190.10 162 266 4.3E-45 T 12-10-2018 MIM_c16320 cf84cc9bbf5f36ab8693b460bd9b4d92 294 SUPERFAMILY SSF46785 3 87 8.39E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c16320 cf84cc9bbf5f36ab8693b460bd9b4d92 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.7E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c16320 cf84cc9bbf5f36ab8693b460bd9b4d92 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.7E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c16320 cf84cc9bbf5f36ab8693b460bd9b4d92 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.7E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c16320 cf84cc9bbf5f36ab8693b460bd9b4d92 294 Gene3D G3DSA:1.10.10.10 1 86 3.0E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c16320 cf84cc9bbf5f36ab8693b460bd9b4d92 294 SUPERFAMILY SSF53850 89 292 4.21E-29 T 12-10-2018 MIM_c16320 cf84cc9bbf5f36ab8693b460bd9b4d92 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.3E-22 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c19660 de353830d17da880bd61db894cc43e0f 129 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 5 122 16.916 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MIM_c19660 de353830d17da880bd61db894cc43e0f 129 TIGRFAM TIGR00494 crcB: protein CrcB 7 119 7.4E-27 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MIM_c19660 de353830d17da880bd61db894cc43e0f 129 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 7 117 2.7E-19 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MIM_c17230 2dcadfafe21d0e45829d7ffa37353bf9 430 ProSitePatterns PS01007 Transposases, Mutator family, signature. 249 273 - T 12-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MIM_c17230 2dcadfafe21d0e45829d7ffa37353bf9 430 Pfam PF00872 Transposase, Mutator family 35 394 3.9E-121 T 12-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MIM_c01250 02bcf7c98601bf80ce2296f5c18df4c2 319 SUPERFAMILY SSF48179 188 293 2.21E-23 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c01250 02bcf7c98601bf80ce2296f5c18df4c2 319 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 189 287 7.4E-19 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MIM_c01250 02bcf7c98601bf80ce2296f5c18df4c2 319 Gene3D G3DSA:3.40.50.720 9 191 8.5E-52 T 12-10-2018 MIM_c01250 02bcf7c98601bf80ce2296f5c18df4c2 319 PIRSF PIRSF000105 10 314 1.9E-74 T 12-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 MIM_c01250 02bcf7c98601bf80ce2296f5c18df4c2 319 Gene3D G3DSA:1.10.1040.10 192 311 3.6E-34 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MIM_c01250 02bcf7c98601bf80ce2296f5c18df4c2 319 SUPERFAMILY SSF51735 14 185 5.61E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c01250 02bcf7c98601bf80ce2296f5c18df4c2 319 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 16 186 1.6E-45 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MIM_c17330 ef57cbeec3a1681f2643dedf054e4b87 406 SUPERFAMILY SSF53686 42 391 6.29E-62 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MIM_c17330 ef57cbeec3a1681f2643dedf054e4b87 406 Gene3D G3DSA:3.40.50.1100 43 390 3.1E-127 T 12-10-2018 MIM_c17330 ef57cbeec3a1681f2643dedf054e4b87 406 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 41 377 2.4E-67 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MIM_c17330 ef57cbeec3a1681f2643dedf054e4b87 406 TIGRFAM TIGR01747 diampropi_NH3ly: diaminopropionate ammonia-lyase family 43 390 3.0E-87 T 12-10-2018 IPR010081 Diaminopropionate ammonia-lyase GO:0008838|GO:0030170 MIM_c17330 ef57cbeec3a1681f2643dedf054e4b87 406 Gene3D G3DSA:3.40.50.1100 75 195 3.1E-127 T 12-10-2018 MIM_c38980 66e5e26b80dc5539419181133ab2f8c0 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 1.1E-26 T 12-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 MIM_c38980 66e5e26b80dc5539419181133ab2f8c0 72 SMART SM00316 2 72 0.007 T 12-10-2018 IPR022967 RNA-binding domain, S1 MIM_c38980 66e5e26b80dc5539419181133ab2f8c0 72 SUPERFAMILY SSF50249 1 70 4.16E-27 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c38980 66e5e26b80dc5539419181133ab2f8c0 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 1.2E-36 T 12-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 MIM_c38980 66e5e26b80dc5539419181133ab2f8c0 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 27.034 T 12-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 MIM_c38980 66e5e26b80dc5539419181133ab2f8c0 72 Gene3D G3DSA:2.40.50.140 1 72 1.6E-36 T 12-10-2018 MIM_c12250 a40f21c7aeb27971c9c97f539309bf63 386 SUPERFAMILY SSF63829 81 383 2.83E-69 T 12-10-2018 MIM_c12250 a40f21c7aeb27971c9c97f539309bf63 386 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 97 370 4.5E-55 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region MIM_c12250 a40f21c7aeb27971c9c97f539309bf63 386 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 98 115 7.9E-12 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MIM_c12250 a40f21c7aeb27971c9c97f539309bf63 386 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 237 259 7.9E-12 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MIM_c12250 a40f21c7aeb27971c9c97f539309bf63 386 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 352 370 7.9E-12 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MIM_c12250 a40f21c7aeb27971c9c97f539309bf63 386 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 307 324 7.9E-12 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MIM_c12250 a40f21c7aeb27971c9c97f539309bf63 386 Gene3D G3DSA:2.120.10.30 57 378 2.2E-94 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MIM_c21350 cceaf395c096a685c6dd9a10842f7522 112 Gene3D G3DSA:3.30.70.120 1 112 9.2E-46 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MIM_c21350 cceaf395c096a685c6dd9a10842f7522 112 PRINTS PR00340 P-II protein signature 52 75 5.7E-44 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MIM_c21350 cceaf395c096a685c6dd9a10842f7522 112 PRINTS PR00340 P-II protein signature 23 41 5.7E-44 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MIM_c21350 cceaf395c096a685c6dd9a10842f7522 112 PRINTS PR00340 P-II protein signature 83 103 5.7E-44 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MIM_c21350 cceaf395c096a685c6dd9a10842f7522 112 PRINTS PR00340 P-II protein signature 2 17 5.7E-44 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MIM_c21350 cceaf395c096a685c6dd9a10842f7522 112 SMART SM00938 4 105 3.6E-66 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MIM_c21350 cceaf395c096a685c6dd9a10842f7522 112 SUPERFAMILY SSF54913 2 112 1.56E-44 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta MIM_c21350 cceaf395c096a685c6dd9a10842f7522 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 12-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 MIM_c21350 cceaf395c096a685c6dd9a10842f7522 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 12-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 MIM_c21350 cceaf395c096a685c6dd9a10842f7522 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.3E-43 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MIM_c21350 cceaf395c096a685c6dd9a10842f7522 112 PIRSF PIRSF039144 1 112 5.4E-54 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MIM_c21040 e886ef463686dd139ebef1b4d2fc5e73 1059 Gene3D G3DSA:3.30.2090.10 179 275 0.0 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c21040 e886ef463686dd139ebef1b4d2fc5e73 1059 SUPERFAMILY SSF82866 812 1038 1.01E-41 T 12-10-2018 MIM_c21040 e886ef463686dd139ebef1b4d2fc5e73 1059 Pfam PF00873 AcrB/AcrD/AcrF family 1 1033 0.0 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c21040 e886ef463686dd139ebef1b4d2fc5e73 1059 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1046 0.0 T 12-10-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0006855|GO:0015562|GO:0016021 MIM_c21040 e886ef463686dd139ebef1b4d2fc5e73 1059 Gene3D G3DSA:3.30.70.1430 579 675 0.0 T 12-10-2018 MIM_c21040 e886ef463686dd139ebef1b4d2fc5e73 1059 Gene3D G3DSA:3.30.70.1440 676 872 0.0 T 12-10-2018 MIM_c21040 e886ef463686dd139ebef1b4d2fc5e73 1059 SUPERFAMILY SSF82714 730 815 1.06E-14 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c21040 e886ef463686dd139ebef1b4d2fc5e73 1059 Gene3D G3DSA:3.30.70.1320 133 332 0.0 T 12-10-2018 MIM_c21040 e886ef463686dd139ebef1b4d2fc5e73 1059 Gene3D G3DSA:3.30.70.1430 38 824 0.0 T 12-10-2018 MIM_c21040 e886ef463686dd139ebef1b4d2fc5e73 1059 SUPERFAMILY SSF82714 182 272 3.27E-21 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c21040 e886ef463686dd139ebef1b4d2fc5e73 1059 SUPERFAMILY SSF82866 296 497 1.03E-49 T 12-10-2018 MIM_c21040 e886ef463686dd139ebef1b4d2fc5e73 1059 Gene3D G3DSA:1.20.1640.10 8 524 0.0 T 12-10-2018 MIM_c21040 e886ef463686dd139ebef1b4d2fc5e73 1059 Gene3D G3DSA:1.20.1640.10 525 1029 0.0 T 12-10-2018 MIM_c21040 e886ef463686dd139ebef1b4d2fc5e73 1059 SUPERFAMILY SSF82693 577 678 8.89E-22 T 12-10-2018 MIM_c21040 e886ef463686dd139ebef1b4d2fc5e73 1059 Gene3D G3DSA:3.30.2090.10 728 816 0.0 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c21040 e886ef463686dd139ebef1b4d2fc5e73 1059 SUPERFAMILY SSF82693 38 131 1.06E-27 T 12-10-2018 MIM_c21040 e886ef463686dd139ebef1b4d2fc5e73 1059 SUPERFAMILY SSF82693 136 330 3.66E-21 T 12-10-2018 MIM_c21040 e886ef463686dd139ebef1b4d2fc5e73 1059 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 6.7E-102 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c21040 e886ef463686dd139ebef1b4d2fc5e73 1059 PRINTS PR00702 Acriflavin resistance protein family signature 628 642 6.7E-102 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c21040 e886ef463686dd139ebef1b4d2fc5e73 1059 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 6.7E-102 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c21040 e886ef463686dd139ebef1b4d2fc5e73 1059 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 6.7E-102 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c21040 e886ef463686dd139ebef1b4d2fc5e73 1059 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 6.7E-102 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c21040 e886ef463686dd139ebef1b4d2fc5e73 1059 PRINTS PR00702 Acriflavin resistance protein family signature 564 581 6.7E-102 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c21040 e886ef463686dd139ebef1b4d2fc5e73 1059 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 6.7E-102 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c21040 e886ef463686dd139ebef1b4d2fc5e73 1059 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 6.7E-102 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c21040 e886ef463686dd139ebef1b4d2fc5e73 1059 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 6.7E-102 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c27790 27217b42ee1d9e96a437a3f54a5d3561 336 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 160 315 7.4E-64 T 12-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c27790 27217b42ee1d9e96a437a3f54a5d3561 336 Gene3D G3DSA:3.40.50.720 4 327 2.0E-151 T 12-10-2018 MIM_c27790 27217b42ee1d9e96a437a3f54a5d3561 336 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 106 2.0E-39 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c27790 27217b42ee1d9e96a437a3f54a5d3561 336 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 327 2.3E-130 T 12-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c27790 27217b42ee1d9e96a437a3f54a5d3561 336 PIRSF PIRSF000149 1 336 3.6E-136 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c27790 27217b42ee1d9e96a437a3f54a5d3561 336 Gene3D G3DSA:3.30.360.10 154 317 2.0E-151 T 12-10-2018 MIM_c27790 27217b42ee1d9e96a437a3f54a5d3561 336 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 153 160 - T 12-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c27790 27217b42ee1d9e96a437a3f54a5d3561 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 112 125 6.2E-39 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c27790 27217b42ee1d9e96a437a3f54a5d3561 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 272 287 6.2E-39 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c27790 27217b42ee1d9e96a437a3f54a5d3561 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 149 167 6.2E-39 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c27790 27217b42ee1d9e96a437a3f54a5d3561 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 232 249 6.2E-39 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c27790 27217b42ee1d9e96a437a3f54a5d3561 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 176 192 6.2E-39 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c27790 27217b42ee1d9e96a437a3f54a5d3561 336 SUPERFAMILY SSF51735 3 176 1.72E-64 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c27790 27217b42ee1d9e96a437a3f54a5d3561 336 SUPERFAMILY SSF55347 155 316 1.82E-69 T 12-10-2018 MIM_c27790 27217b42ee1d9e96a437a3f54a5d3561 336 SMART SM00846 3 155 3.7E-96 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c17420 b22e093691a6544e89ab45f6cc2aa4bc 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 42 222 6.3E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c17420 b22e093691a6544e89ab45f6cc2aa4bc 225 Gene3D G3DSA:1.10.3720.10 11 223 7.8E-44 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c17420 b22e093691a6544e89ab45f6cc2aa4bc 225 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 24 116 1.8E-17 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c17420 b22e093691a6544e89ab45f6cc2aa4bc 225 SUPERFAMILY SSF161098 23 219 4.32E-37 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c25100 15dcd1228caceb6354965f28d58a4d7e 255 Pfam PF08241 Methyltransferase domain 43 131 1.8E-17 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 MIM_c25100 15dcd1228caceb6354965f28d58a4d7e 255 Gene3D G3DSA:3.40.50.150 21 246 1.0E-83 T 12-10-2018 MIM_c25100 15dcd1228caceb6354965f28d58a4d7e 255 Gene3D G3DSA:1.10.10.2560 137 236 1.0E-83 T 12-10-2018 MIM_c25100 15dcd1228caceb6354965f28d58a4d7e 255 SUPERFAMILY SSF53335 1 185 3.62E-32 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c16370 fa70b3161b6f7391a871cb86f1b79540 214 Gene3D G3DSA:3.30.1020.10 148 212 4.5E-27 T 12-10-2018 MIM_c16370 fa70b3161b6f7391a871cb86f1b79540 214 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 158 190 3.3E-10 T 12-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MIM_c16370 fa70b3161b6f7391a871cb86f1b79540 214 PIRSF PIRSF000239 1 211 2.1E-78 T 12-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MIM_c16370 fa70b3161b6f7391a871cb86f1b79540 214 Gene3D G3DSA:3.40.30.10 1 147 5.3E-52 T 12-10-2018 MIM_c16370 fa70b3161b6f7391a871cb86f1b79540 214 Pfam PF00578 AhpC/TSA family 8 136 2.8E-33 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MIM_c16370 fa70b3161b6f7391a871cb86f1b79540 214 SUPERFAMILY SSF52833 5 211 1.04E-68 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c38000 1807a8b3054105e540036bbafeaa090d 449 Gene3D G3DSA:1.10.287.470 143 233 4.6E-7 T 12-10-2018 MIM_c38000 1807a8b3054105e540036bbafeaa090d 449 SUPERFAMILY SSF111369 79 164 8.24E-9 T 12-10-2018 MIM_c38000 1807a8b3054105e540036bbafeaa090d 449 Gene3D G3DSA:2.40.50.100 80 142 3.0E-9 T 12-10-2018 MIM_c38000 1807a8b3054105e540036bbafeaa090d 449 Gene3D G3DSA:2.40.30.170 279 399 1.4E-30 T 12-10-2018 MIM_c38000 1807a8b3054105e540036bbafeaa090d 449 SUPERFAMILY SSF111369 208 314 1.7E-5 T 12-10-2018 MIM_c38000 1807a8b3054105e540036bbafeaa090d 449 Pfam PF13533 Biotin-lipoyl like 81 128 5.3E-12 T 12-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain MIM_c38000 1807a8b3054105e540036bbafeaa090d 449 Pfam PF13437 HlyD family secretion protein 264 344 5.5E-12 T 12-10-2018 MIM_c34380 896268f40ac3ecb2182ef4cad6ec0978 289 SUPERFAMILY SSF51215 27 150 2.88E-6 T 12-10-2018 IPR037923 Transcription regulator HTH-like MIM_c34380 896268f40ac3ecb2182ef4cad6ec0978 289 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 229 271 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MIM_c34380 896268f40ac3ecb2182ef4cad6ec0978 289 SUPERFAMILY SSF46689 175 224 3.14E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c34380 896268f40ac3ecb2182ef4cad6ec0978 289 Pfam PF12833 Helix-turn-helix domain 198 276 6.0E-22 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c34380 896268f40ac3ecb2182ef4cad6ec0978 289 Gene3D G3DSA:1.10.10.60 171 278 4.5E-26 T 12-10-2018 MIM_c34380 896268f40ac3ecb2182ef4cad6ec0978 289 SMART SM00342 192 275 2.6E-23 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c34380 896268f40ac3ecb2182ef4cad6ec0978 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 244 259 6.9E-7 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MIM_c34380 896268f40ac3ecb2182ef4cad6ec0978 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 259 275 6.9E-7 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MIM_c34380 896268f40ac3ecb2182ef4cad6ec0978 289 SUPERFAMILY SSF46689 228 276 2.87E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c12450 481f3ec71a0e167d414057dbfc3b59c0 304 Pfam PF00106 short chain dehydrogenase 8 195 1.5E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c12450 481f3ec71a0e167d414057dbfc3b59c0 304 SUPERFAMILY SSF51735 6 257 5.88E-63 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c12450 481f3ec71a0e167d414057dbfc3b59c0 304 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 213 2.9E-6 T 12-10-2018 MIM_c12450 481f3ec71a0e167d414057dbfc3b59c0 304 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c12450 481f3ec71a0e167d414057dbfc3b59c0 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 8.3E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c12450 481f3ec71a0e167d414057dbfc3b59c0 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 8.3E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c12450 481f3ec71a0e167d414057dbfc3b59c0 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 8.3E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c12450 481f3ec71a0e167d414057dbfc3b59c0 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.4E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c12450 481f3ec71a0e167d414057dbfc3b59c0 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 4.4E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c12450 481f3ec71a0e167d414057dbfc3b59c0 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 4.4E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c12450 481f3ec71a0e167d414057dbfc3b59c0 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 4.4E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c12450 481f3ec71a0e167d414057dbfc3b59c0 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 4.4E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c12450 481f3ec71a0e167d414057dbfc3b59c0 304 Gene3D G3DSA:3.40.50.720 6 293 4.0E-71 T 12-10-2018 MIM_c17950 c8874d4556516eabb9ba5e53d0c9eea6 362 SUPERFAMILY SSF52540 190 352 4.39E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c17950 c8874d4556516eabb9ba5e53d0c9eea6 362 Pfam PF01926 50S ribosome-binding GTPase 192 310 1.2E-21 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 MIM_c17950 c8874d4556516eabb9ba5e53d0c9eea6 362 Pfam PF16360 GTP-binding GTPase Middle Region 106 184 4.1E-29 T 12-10-2018 IPR032305 GTP-binding protein, middle domain MIM_c17950 c8874d4556516eabb9ba5e53d0c9eea6 362 PIRSF PIRSF006809 1 360 1.8E-135 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 MIM_c17950 c8874d4556516eabb9ba5e53d0c9eea6 362 Hamap MF_00900 GTPase HflX [hflX]. 19 362 46.179 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 MIM_c17950 c8874d4556516eabb9ba5e53d0c9eea6 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 213 231 5.4E-9 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 MIM_c17950 c8874d4556516eabb9ba5e53d0c9eea6 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 259 277 5.4E-9 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 MIM_c17950 c8874d4556516eabb9ba5e53d0c9eea6 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 192 212 5.4E-9 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 MIM_c17950 c8874d4556516eabb9ba5e53d0c9eea6 362 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 189 346 1.5E-12 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MIM_c17950 c8874d4556516eabb9ba5e53d0c9eea6 362 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 2 350 5.9E-148 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 MIM_c17950 c8874d4556516eabb9ba5e53d0c9eea6 362 Gene3D G3DSA:3.40.50.300 191 354 5.0E-40 T 12-10-2018 MIM_c17950 c8874d4556516eabb9ba5e53d0c9eea6 362 Gene3D G3DSA:3.40.50.11060 11 130 5.5E-36 T 12-10-2018 MIM_c17950 c8874d4556516eabb9ba5e53d0c9eea6 362 Pfam PF13167 GTP-binding GTPase N-terminal 18 104 7.8E-29 T 12-10-2018 IPR025121 GTPase HflX, N-terminal MIM_c31640 53cb4a1504015a0ab771892733e727c1 456 ProSitePatterns PS00217 Sugar transport proteins signature 2. 119 144 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MIM_c31640 53cb4a1504015a0ab771892733e727c1 456 Gene3D G3DSA:1.20.1250.20 15 222 1.1E-41 T 12-10-2018 MIM_c31640 53cb4a1504015a0ab771892733e727c1 456 Gene3D G3DSA:1.20.1250.20 248 433 6.7E-22 T 12-10-2018 MIM_c31640 53cb4a1504015a0ab771892733e727c1 456 ProSitePatterns PS00216 Sugar transport proteins signature 1. 77 92 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MIM_c31640 53cb4a1504015a0ab771892733e727c1 456 SUPERFAMILY SSF103473 14 426 5.75E-76 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c31640 53cb4a1504015a0ab771892733e727c1 456 Pfam PF07690 Major Facilitator Superfamily 26 294 1.5E-32 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c09710 8f093dfe8abc22917b0f92e86a8d026a 606 Gene3D G3DSA:3.40.710.10 313 496 1.3E-102 T 12-10-2018 MIM_c09710 8f093dfe8abc22917b0f92e86a8d026a 606 Hamap MF_02080 Peptidoglycan D,D-transpeptidase FtsI [ftsI]. 40 590 39.533 T 12-10-2018 IPR037532 Peptidoglycan D,D-transpeptidase FtsI GO:0005887|GO:0008658|GO:0008955|GO:0009252|GO:0051301 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MIM_c09710 8f093dfe8abc22917b0f92e86a8d026a 606 SUPERFAMILY SSF56519 84 251 2.49E-43 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 MIM_c09710 8f093dfe8abc22917b0f92e86a8d026a 606 Gene3D G3DSA:3.30.450.330 253 579 1.3E-102 T 12-10-2018 MIM_c09710 8f093dfe8abc22917b0f92e86a8d026a 606 Pfam PF00905 Penicillin binding protein transpeptidase domain 277 575 1.8E-71 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MIM_c09710 8f093dfe8abc22917b0f92e86a8d026a 606 Gene3D G3DSA:3.90.1310.30 81 251 7.7E-45 T 12-10-2018 MIM_c09710 8f093dfe8abc22917b0f92e86a8d026a 606 SUPERFAMILY SSF56601 204 588 2.0E-82 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MIM_c09710 8f093dfe8abc22917b0f92e86a8d026a 606 Pfam PF03717 Penicillin-binding Protein dimerisation domain 88 236 2.0E-19 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MIM_c06070 c31c3eeeae34e3cd3f8f35d7e29382e8 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 285 1.0E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c06070 c31c3eeeae34e3cd3f8f35d7e29382e8 286 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 43 284 7.9E-89 T 12-10-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 MIM_c06070 c31c3eeeae34e3cd3f8f35d7e29382e8 286 Gene3D G3DSA:1.10.3720.10 87 284 2.4E-32 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c06070 c31c3eeeae34e3cd3f8f35d7e29382e8 286 SUPERFAMILY SSF161098 89 280 4.06E-34 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c20910 50edf4d3f447eee078266df65aa498ef 610 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 340 471 3.9E-9 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 MIM_c20910 50edf4d3f447eee078266df65aa498ef 610 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 161 8.5E-37 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 MIM_c20910 50edf4d3f447eee078266df65aa498ef 610 SUPERFAMILY SSF48179 475 603 1.93E-10 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c20910 50edf4d3f447eee078266df65aa498ef 610 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 277 1.8E-21 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MIM_c20910 50edf4d3f447eee078266df65aa498ef 610 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 477 590 8.4E-9 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MIM_c20910 50edf4d3f447eee078266df65aa498ef 610 SUPERFAMILY SSF51735 4 163 1.52E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c20910 50edf4d3f447eee078266df65aa498ef 610 Gene3D G3DSA:1.10.1040.10 475 604 1.7E-13 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MIM_c20910 50edf4d3f447eee078266df65aa498ef 610 Gene3D G3DSA:3.40.50.720 307 474 1.0E-15 T 12-10-2018 MIM_c20910 50edf4d3f447eee078266df65aa498ef 610 Gene3D G3DSA:1.10.1040.10 165 295 1.3E-25 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MIM_c20910 50edf4d3f447eee078266df65aa498ef 610 Gene3D G3DSA:3.40.50.720 2 164 2.7E-44 T 12-10-2018 MIM_c20910 50edf4d3f447eee078266df65aa498ef 610 SUPERFAMILY SSF51735 347 475 8.08E-10 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c20910 50edf4d3f447eee078266df65aa498ef 610 SUPERFAMILY SSF48179 165 291 2.38E-22 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c18560 de4c7c60bee5f48bcc59e0959d6c52b9 175 Hamap MF_00682 Co-chaperone protein HscB [hscB]. 6 175 20.385 T 12-10-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MIM_c18560 de4c7c60bee5f48bcc59e0959d6c52b9 175 Pfam PF07743 HSCB C-terminal oligomerisation domain 92 168 2.6E-16 T 12-10-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MIM_c18560 de4c7c60bee5f48bcc59e0959d6c52b9 175 SMART SM00271 6 71 1.6E-5 T 12-10-2018 IPR001623 DnaJ domain MIM_c18560 de4c7c60bee5f48bcc59e0959d6c52b9 175 SUPERFAMILY SSF46565 7 77 2.22E-16 T 12-10-2018 IPR036869 Chaperone J-domain superfamily MIM_c18560 de4c7c60bee5f48bcc59e0959d6c52b9 175 TIGRFAM TIGR00714 hscB: Fe-S protein assembly co-chaperone HscB 25 170 2.5E-24 T 12-10-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MIM_c18560 de4c7c60bee5f48bcc59e0959d6c52b9 175 Gene3D G3DSA:1.10.287.110 2 77 4.4E-22 T 12-10-2018 IPR036869 Chaperone J-domain superfamily MIM_c18560 de4c7c60bee5f48bcc59e0959d6c52b9 175 SUPERFAMILY SSF47144 83 170 6.8E-20 T 12-10-2018 IPR036386 HscB, C-terminal domain superfamily GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MIM_c18560 de4c7c60bee5f48bcc59e0959d6c52b9 175 Gene3D G3DSA:1.20.1280.20 85 173 1.2E-18 T 12-10-2018 IPR036386 HscB, C-terminal domain superfamily GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MIM_c36670 674ee41594fb0845a8e31486c9ed9bef 456 Pfam PF01266 FAD dependent oxidoreductase 51 411 7.5E-50 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MIM_c36670 674ee41594fb0845a8e31486c9ed9bef 456 Gene3D G3DSA:3.30.9.10 144 371 2.9E-65 T 12-10-2018 MIM_c36670 674ee41594fb0845a8e31486c9ed9bef 456 Gene3D G3DSA:3.50.50.60 51 412 2.9E-65 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c36670 674ee41594fb0845a8e31486c9ed9bef 456 SUPERFAMILY SSF51905 51 425 1.68E-40 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c30600 a853e0bd92010951332f0cdda4ed657b 558 Gene3D G3DSA:3.40.50.970 1 180 1.6E-54 T 12-10-2018 MIM_c30600 a853e0bd92010951332f0cdda4ed657b 558 Gene3D G3DSA:3.40.50.970 366 552 2.3E-53 T 12-10-2018 MIM_c30600 a853e0bd92010951332f0cdda4ed657b 558 Gene3D G3DSA:3.40.50.1220 181 355 8.8E-40 T 12-10-2018 MIM_c30600 a853e0bd92010951332f0cdda4ed657b 558 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 424 443 - T 12-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 MIM_c30600 a853e0bd92010951332f0cdda4ed657b 558 SUPERFAMILY SSF52518 370 538 5.36E-52 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c30600 a853e0bd92010951332f0cdda4ed657b 558 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 388 534 6.4E-39 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MIM_c30600 a853e0bd92010951332f0cdda4ed657b 558 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 190 327 6.3E-29 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MIM_c30600 a853e0bd92010951332f0cdda4ed657b 558 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 170 8.2E-49 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MIM_c30600 a853e0bd92010951332f0cdda4ed657b 558 SUPERFAMILY SSF52518 4 179 6.34E-49 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c30600 a853e0bd92010951332f0cdda4ed657b 558 SUPERFAMILY SSF52467 155 356 1.57E-37 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MIM_c17560 a366da31d7c6583e2d0235b1961eacb8 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 321 2.0E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c17560 a366da31d7c6583e2d0235b1961eacb8 325 SUPERFAMILY SSF53850 110 285 4.04E-14 T 12-10-2018 MIM_c17560 a366da31d7c6583e2d0235b1961eacb8 325 PIRSF PIRSF017082 2 325 4.1E-74 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c17560 a366da31d7c6583e2d0235b1961eacb8 325 Gene3D G3DSA:3.40.190.150 29 315 8.7E-100 T 12-10-2018 MIM_c17560 a366da31d7c6583e2d0235b1961eacb8 325 Gene3D G3DSA:3.40.190.10 127 250 8.7E-100 T 12-10-2018 MIM_c05850 cd9b5729f4735e409e305e085b8419da 165 Gene3D G3DSA:3.90.1720.10 18 158 1.2E-38 T 12-10-2018 MIM_c05850 cd9b5729f4735e409e305e085b8419da 165 SUPERFAMILY SSF54001 40 161 4.9E-36 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily MIM_c05850 cd9b5729f4735e409e305e085b8419da 165 Pfam PF00877 NlpC/P60 family 55 161 3.1E-27 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain MIM_c01200 adf5e29687797867f2d0dfdfb64a4bc5 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.0E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01200 adf5e29687797867f2d0dfdfb64a4bc5 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 4.0E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01200 adf5e29687797867f2d0dfdfb64a4bc5 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 4.0E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01200 adf5e29687797867f2d0dfdfb64a4bc5 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 4.0E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01200 adf5e29687797867f2d0dfdfb64a4bc5 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 4.0E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01200 adf5e29687797867f2d0dfdfb64a4bc5 306 SUPERFAMILY SSF51735 4 232 2.55E-68 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c01200 adf5e29687797867f2d0dfdfb64a4bc5 306 Pfam PF00106 short chain dehydrogenase 9 201 1.8E-51 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01200 adf5e29687797867f2d0dfdfb64a4bc5 306 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 9.8E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01200 adf5e29687797867f2d0dfdfb64a4bc5 306 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 9.8E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01200 adf5e29687797867f2d0dfdfb64a4bc5 306 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 9.8E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01200 adf5e29687797867f2d0dfdfb64a4bc5 306 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c01200 adf5e29687797867f2d0dfdfb64a4bc5 306 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 203 4.4E-7 T 12-10-2018 MIM_c01200 adf5e29687797867f2d0dfdfb64a4bc5 306 Gene3D G3DSA:3.40.50.720 8 295 1.8E-75 T 12-10-2018 MIM_c15790 0a1a2a2ae7c2628a967568dd952650cc 252 Gene3D G3DSA:3.40.50.720 1 251 2.8E-77 T 12-10-2018 MIM_c15790 0a1a2a2ae7c2628a967568dd952650cc 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 245 8.8E-48 T 12-10-2018 MIM_c15790 0a1a2a2ae7c2628a967568dd952650cc 252 SUPERFAMILY SSF51735 5 245 1.18E-61 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c15790 0a1a2a2ae7c2628a967568dd952650cc 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 7.6E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c15790 0a1a2a2ae7c2628a967568dd952650cc 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 7.6E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c15790 0a1a2a2ae7c2628a967568dd952650cc 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 7.6E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c15790 0a1a2a2ae7c2628a967568dd952650cc 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c15790 0a1a2a2ae7c2628a967568dd952650cc 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.4E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c15790 0a1a2a2ae7c2628a967568dd952650cc 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.4E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c15790 0a1a2a2ae7c2628a967568dd952650cc 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 1.4E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c15790 0a1a2a2ae7c2628a967568dd952650cc 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.4E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c15790 0a1a2a2ae7c2628a967568dd952650cc 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.4E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c15790 0a1a2a2ae7c2628a967568dd952650cc 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.4E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c39630 ddcc2767f0bc72c925052a049a953fd0 93 PRINTS PR00973 Ribosomal protein S17 family signature 32 55 6.8E-11 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c39630 ddcc2767f0bc72c925052a049a953fd0 93 PRINTS PR00973 Ribosomal protein S17 family signature 74 81 6.8E-11 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c39630 ddcc2767f0bc72c925052a049a953fd0 93 PRINTS PR00973 Ribosomal protein S17 family signature 64 74 6.8E-11 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c39630 ddcc2767f0bc72c925052a049a953fd0 93 ProSitePatterns PS00056 Ribosomal protein S17 signature. 64 76 - T 12-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39630 ddcc2767f0bc72c925052a049a953fd0 93 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 14 84 2.0E-34 T 12-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c39630 ddcc2767f0bc72c925052a049a953fd0 93 SUPERFAMILY SSF50249 12 91 2.18E-30 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c39630 ddcc2767f0bc72c925052a049a953fd0 93 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 13 84 4.0E-31 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c39630 ddcc2767f0bc72c925052a049a953fd0 93 Gene3D G3DSA:2.40.50.140 10 91 5.2E-33 T 12-10-2018 MIM_c39630 ddcc2767f0bc72c925052a049a953fd0 93 Pfam PF00366 Ribosomal protein S17 18 84 2.1E-30 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c39630 ddcc2767f0bc72c925052a049a953fd0 93 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 13 88 24.31 T 12-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c36040 863f77e805e03ae46d729c00c15091e9 199 SUPERFAMILY SSF52218 1 198 2.23E-59 T 12-10-2018 IPR029039 Flavoprotein-like superfamily MIM_c36040 863f77e805e03ae46d729c00c15091e9 199 Hamap MF_01017 NAD(P)H dehydrogenase (quinone). 1 199 45.948 T 12-10-2018 IPR037513 NAD(P)H dehydrogenase (quinone), prokaryotic GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 MIM_c36040 863f77e805e03ae46d729c00c15091e9 199 Pfam PF03358 NADPH-dependent FMN reductase 4 142 2.1E-11 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 MIM_c36040 863f77e805e03ae46d729c00c15091e9 199 Gene3D G3DSA:3.40.50.360 1 199 3.6E-76 T 12-10-2018 IPR029039 Flavoprotein-like superfamily MIM_c36040 863f77e805e03ae46d729c00c15091e9 199 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 2 197 4.5E-97 T 12-10-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 Pfam PF14520 Helix-hairpin-helix domain 459 513 1.4E-5 T 12-10-2018 MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 SMART SM00278 524 543 180.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 SMART SM00278 556 575 160.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 SMART SM00278 458 477 87.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 SMART SM00278 492 511 0.49 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 Hamap MF_01588 DNA ligase [ligA]. 7 677 53.38 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 Gene3D G3DSA:1.10.150.20 517 594 3.0E-28 T 12-10-2018 MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 Gene3D G3DSA:2.40.50.140 330 401 4.1E-34 T 12-10-2018 MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 SUPERFAMILY SSF56091 7 327 1.5E-114 T 12-10-2018 MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 Gene3D G3DSA:1.10.287.610 7 73 2.2E-26 T 12-10-2018 MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 126 155 - T 12-10-2018 IPR018239 NAD-dependent DNA ligase, active site MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 Gene3D G3DSA:3.40.50.10190 595 678 1.1E-27 T 12-10-2018 IPR036420 BRCT domain superfamily MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 Gene3D G3DSA:1.10.150.20 444 516 6.6E-28 T 12-10-2018 MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 343 358 - T 12-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 334 410 1.5E-35 T 12-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 SMART SM00532 8 460 7.7E-259 T 12-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 Pfam PF12826 Helix-hairpin-helix motif 522 584 8.3E-23 T 12-10-2018 MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 602 676 4.9E-15 T 12-10-2018 IPR001357 BRCT domain MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 SUPERFAMILY SSF52113 601 677 3.49E-20 T 12-10-2018 IPR036420 BRCT domain superfamily MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 8 330 2.5E-119 T 12-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 SUPERFAMILY SSF50249 329 412 6.34E-29 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 SMART SM00292 603 679 4.5E-13 T 12-10-2018 IPR001357 BRCT domain MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 Gene3D G3DSA:3.30.470.90 74 329 4.6E-95 T 12-10-2018 MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 419 446 5.8E-11 T 12-10-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 16 672 1.3E-249 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 SUPERFAMILY SSF47781 415 595 3.34E-62 T 12-10-2018 IPR010994 RuvA domain 2-like MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 Gene3D G3DSA:2.20.70.80 403 443 4.0E-18 T 12-10-2018 MIM_c24280 79f8b4e439388c51bafa0bbc85774570 679 PIRSF PIRSF001604 1 679 3.1E-243 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 MIM_c30700 c3dcfd648e70bf57c11db30c8bacf407 392 Pfam PF01266 FAD dependent oxidoreductase 9 361 9.6E-55 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MIM_c30700 c3dcfd648e70bf57c11db30c8bacf407 392 SUPERFAMILY SSF51905 8 380 1.23E-44 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c30700 c3dcfd648e70bf57c11db30c8bacf407 392 Gene3D G3DSA:3.30.9.10 96 320 5.1E-84 T 12-10-2018 MIM_c30700 c3dcfd648e70bf57c11db30c8bacf407 392 Gene3D G3DSA:3.50.50.60 9 361 5.1E-84 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c20520 9bdc3ed6bf448d1c3c24e95e0a6d85cb 348 Pfam PF04909 Amidohydrolase 35 346 3.5E-30 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MIM_c20520 9bdc3ed6bf448d1c3c24e95e0a6d85cb 348 SUPERFAMILY SSF51556 33 346 9.36E-32 T 12-10-2018 IPR032466 Metal-dependent hydrolase MIM_c20520 9bdc3ed6bf448d1c3c24e95e0a6d85cb 348 Gene3D G3DSA:3.20.20.140 32 348 1.0E-66 T 12-10-2018 MIM_c01600 11f41aa4389ac8a44e74ff4dd5a3c60a 439 TIGRFAM TIGR04555 sulfite_DH_soxC: sulfite dehydrogenase 21 437 7.2E-184 T 12-10-2018 IPR030835 Sulfite dehydrogenase SoxC MIM_c01600 11f41aa4389ac8a44e74ff4dd5a3c60a 439 SUPERFAMILY SSF56524 97 343 6.8E-71 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 MIM_c01600 11f41aa4389ac8a44e74ff4dd5a3c60a 439 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 310 424 1.4E-17 T 12-10-2018 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 MIM_c01600 11f41aa4389ac8a44e74ff4dd5a3c60a 439 Gene3D G3DSA:2.60.40.650 312 439 4.5E-49 T 12-10-2018 MIM_c01600 11f41aa4389ac8a44e74ff4dd5a3c60a 439 Pfam PF00174 Oxidoreductase molybdopterin binding domain 130 289 1.5E-47 T 12-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 MIM_c01600 11f41aa4389ac8a44e74ff4dd5a3c60a 439 SUPERFAMILY SSF81296 313 428 2.59E-30 T 12-10-2018 IPR014756 Immunoglobulin E-set MIM_c01600 11f41aa4389ac8a44e74ff4dd5a3c60a 439 PRINTS PR00407 Eukaryotic molybdopterin domain signature 393 405 3.1E-19 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 MIM_c01600 11f41aa4389ac8a44e74ff4dd5a3c60a 439 PRINTS PR00407 Eukaryotic molybdopterin domain signature 336 350 3.1E-19 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 MIM_c01600 11f41aa4389ac8a44e74ff4dd5a3c60a 439 PRINTS PR00407 Eukaryotic molybdopterin domain signature 255 268 3.1E-19 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 MIM_c01600 11f41aa4389ac8a44e74ff4dd5a3c60a 439 PRINTS PR00407 Eukaryotic molybdopterin domain signature 118 134 3.1E-19 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 MIM_c01600 11f41aa4389ac8a44e74ff4dd5a3c60a 439 PRINTS PR00407 Eukaryotic molybdopterin domain signature 271 284 3.1E-19 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 MIM_c01600 11f41aa4389ac8a44e74ff4dd5a3c60a 439 PRINTS PR00407 Eukaryotic molybdopterin domain signature 192 207 3.1E-19 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 MIM_c01600 11f41aa4389ac8a44e74ff4dd5a3c60a 439 Gene3D G3DSA:3.90.420.10 57 311 3.5E-85 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 MIM_c00820 07ed1700cf7ed2ba5253dd0862b77ea6 422 Pfam PF13629 Pilus formation protein N terminal region 28 95 7.0E-16 T 12-10-2018 IPR032789 Pilus formation protein, N-terminal MIM_c00820 07ed1700cf7ed2ba5253dd0862b77ea6 422 PRINTS PR00811 Bacterial general secretion pathway protein D signature 217 241 4.5E-15 T 12-10-2018 IPR001775 GspD/PilQ family MIM_c00820 07ed1700cf7ed2ba5253dd0862b77ea6 422 PRINTS PR00811 Bacterial general secretion pathway protein D signature 346 364 4.5E-15 T 12-10-2018 IPR001775 GspD/PilQ family MIM_c00820 07ed1700cf7ed2ba5253dd0862b77ea6 422 PRINTS PR00811 Bacterial general secretion pathway protein D signature 369 383 4.5E-15 T 12-10-2018 IPR001775 GspD/PilQ family MIM_c00820 07ed1700cf7ed2ba5253dd0862b77ea6 422 Pfam PF00263 Bacterial type II and III secretion system protein 221 382 1.3E-44 T 12-10-2018 IPR004846 Type II/III secretion system GO:0009306 MIM_c30120 5f6096323793188fdde9b827e50ffa93 367 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 89 292 1.1E-38 T 12-10-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 MIM_c30120 5f6096323793188fdde9b827e50ffa93 367 Pfam PF10503 Esterase PHB depolymerase 87 291 3.5E-66 T 12-10-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 MIM_c30120 5f6096323793188fdde9b827e50ffa93 367 SUPERFAMILY SSF53474 80 334 7.43E-34 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c30120 5f6096323793188fdde9b827e50ffa93 367 Gene3D G3DSA:3.40.50.1820 71 363 1.8E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c21820 f1815e324a59ec1b956fe18906c0de64 340 SUPERFAMILY SSF55681 93 339 6.47E-75 T 12-10-2018 MIM_c21820 f1815e324a59ec1b956fe18906c0de64 340 Gene3D G3DSA:3.30.930.10 9 340 7.8E-112 T 12-10-2018 MIM_c21820 f1815e324a59ec1b956fe18906c0de64 340 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 338 45.252 T 12-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 MIM_c21820 f1815e324a59ec1b956fe18906c0de64 340 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 21 88 5.0E-19 T 12-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MIM_c21820 f1815e324a59ec1b956fe18906c0de64 340 Pfam PF01409 tRNA synthetases class II core domain (F) 93 338 2.1E-93 T 12-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 MIM_c21820 f1815e324a59ec1b956fe18906c0de64 340 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 43 339 2.5E-96 T 12-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 MIM_c21820 f1815e324a59ec1b956fe18906c0de64 340 SUPERFAMILY SSF46589 15 100 1.46E-18 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 MIM_c25560 35830965b64290899d16f198bb773a1a 543 Pfam PF13403 Hint domain 204 340 1.1E-43 T 12-10-2018 IPR028992 Hedgehog/Intein (Hint) domain MIM_c25560 35830965b64290899d16f198bb773a1a 543 SUPERFAMILY SSF51294 203 318 2.94E-15 T 12-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MIM_c20560 9d4bbb12628f4cdfc0df97cb1ebb849f 241 Pfam PF12697 Alpha/beta hydrolase family 11 231 7.5E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c20560 9d4bbb12628f4cdfc0df97cb1ebb849f 241 Gene3D G3DSA:3.40.50.1820 3 241 3.8E-46 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c20560 9d4bbb12628f4cdfc0df97cb1ebb849f 241 SUPERFAMILY SSF53474 7 239 4.86E-32 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c34870 c1c8f1a2ef1e3acf87a31afb53cba673 360 SMART SM00354 13 83 2.3E-22 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MIM_c34870 c1c8f1a2ef1e3acf87a31afb53cba673 360 Gene3D G3DSA:1.10.260.40 12 71 1.5E-18 T 12-10-2018 MIM_c34870 c1c8f1a2ef1e3acf87a31afb53cba673 360 ProSitePatterns PS00356 LacI-type HTH domain signature. 16 34 - T 12-10-2018 MIM_c34870 c1c8f1a2ef1e3acf87a31afb53cba673 360 Pfam PF00356 Bacterial regulatory proteins, lacI family 15 60 1.1E-13 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MIM_c34870 c1c8f1a2ef1e3acf87a31afb53cba673 360 Gene3D G3DSA:3.40.50.2300 74 337 2.9E-68 T 12-10-2018 MIM_c34870 c1c8f1a2ef1e3acf87a31afb53cba673 360 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 15 25 4.0E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MIM_c34870 c1c8f1a2ef1e3acf87a31afb53cba673 360 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 25 35 4.0E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MIM_c34870 c1c8f1a2ef1e3acf87a31afb53cba673 360 Pfam PF13377 Periplasmic binding protein-like domain 181 345 1.5E-30 T 12-10-2018 MIM_c34870 c1c8f1a2ef1e3acf87a31afb53cba673 360 SUPERFAMILY SSF47413 13 71 1.33E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c34870 c1c8f1a2ef1e3acf87a31afb53cba673 360 Gene3D G3DSA:3.40.50.2300 173 342 2.9E-68 T 12-10-2018 MIM_c34870 c1c8f1a2ef1e3acf87a31afb53cba673 360 SUPERFAMILY SSF53822 72 349 7.43E-63 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c05600 fd862cad7f0ad3353fe0ce67e400d861 408 Pfam PF02222 ATP-grasp domain 130 308 2.9E-52 T 12-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type MIM_c05600 fd862cad7f0ad3353fe0ce67e400d861 408 Hamap MF_01643 Formate-dependent phosphoribosylglycinamide formyltransferase [purT]. 14 405 50.383 T 12-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 MIM_c05600 fd862cad7f0ad3353fe0ce67e400d861 408 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 20 404 7.5E-172 T 12-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 MIM_c05600 fd862cad7f0ad3353fe0ce67e400d861 408 SUPERFAMILY SSF51246 334 404 1.32E-14 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MIM_c05600 fd862cad7f0ad3353fe0ce67e400d861 408 Gene3D G3DSA:3.40.50.20 9 129 2.9E-51 T 12-10-2018 MIM_c05600 fd862cad7f0ad3353fe0ce67e400d861 408 Pfam PF01370 NAD dependent epimerase/dehydratase family 25 87 1.2E-6 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MIM_c05600 fd862cad7f0ad3353fe0ce67e400d861 408 Gene3D G3DSA:3.30.1490.20 130 204 3.0E-32 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MIM_c05600 fd862cad7f0ad3353fe0ce67e400d861 408 Gene3D G3DSA:3.30.470.20 205 408 3.3E-59 T 12-10-2018 MIM_c05600 fd862cad7f0ad3353fe0ce67e400d861 408 SUPERFAMILY SSF52440 10 119 2.01E-32 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MIM_c05600 fd862cad7f0ad3353fe0ce67e400d861 408 SUPERFAMILY SSF56059 120 327 1.36E-54 T 12-10-2018 MIM_c11590 d924583fa0cb86a89f7d6c91e8751545 258 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 38 253 4.5E-59 T 12-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 MIM_c11590 d924583fa0cb86a89f7d6c91e8751545 258 Gene3D G3DSA:3.40.190.10 34 255 2.2E-75 T 12-10-2018 MIM_c11590 d924583fa0cb86a89f7d6c91e8751545 258 SUPERFAMILY SSF53850 32 258 7.17E-64 T 12-10-2018 MIM_c11590 d924583fa0cb86a89f7d6c91e8751545 258 Gene3D G3DSA:3.40.190.10 112 218 2.2E-75 T 12-10-2018 MIM_c11590 d924583fa0cb86a89f7d6c91e8751545 258 Pfam PF13531 Bacterial extracellular solute-binding protein 33 256 2.0E-50 T 12-10-2018 MIM_c11590 d924583fa0cb86a89f7d6c91e8751545 258 PIRSF PIRSF004846 1 258 1.0E-79 T 12-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 MIM_c08120 9eb2e12bdb0fdee1e71d3584380f8f65 350 PIRSF PIRSF500176 23 350 1.8E-88 T 12-10-2018 MIM_c08120 9eb2e12bdb0fdee1e71d3584380f8f65 350 Pfam PF00710 Asparaginase, N-terminal 27 215 1.7E-55 T 12-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 MIM_c08120 9eb2e12bdb0fdee1e71d3584380f8f65 350 Gene3D G3DSA:3.40.50.40 233 348 2.0E-33 T 12-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 MIM_c08120 9eb2e12bdb0fdee1e71d3584380f8f65 350 Gene3D G3DSA:3.40.50.1170 20 232 4.9E-69 T 12-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 MIM_c08120 9eb2e12bdb0fdee1e71d3584380f8f65 350 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 105 115 - T 12-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 MIM_c08120 9eb2e12bdb0fdee1e71d3584380f8f65 350 SUPERFAMILY SSF53774 22 341 9.29E-98 T 12-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 MIM_c08120 9eb2e12bdb0fdee1e71d3584380f8f65 350 PIRSF PIRSF001220 21 350 1.2E-95 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c08120 9eb2e12bdb0fdee1e71d3584380f8f65 350 PRINTS PR00139 Asparaginase/glutaminase family signature 278 296 3.5E-17 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c08120 9eb2e12bdb0fdee1e71d3584380f8f65 350 PRINTS PR00139 Asparaginase/glutaminase family signature 27 38 3.5E-17 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c08120 9eb2e12bdb0fdee1e71d3584380f8f65 350 PRINTS PR00139 Asparaginase/glutaminase family signature 104 122 3.5E-17 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c08120 9eb2e12bdb0fdee1e71d3584380f8f65 350 SMART SM00870 26 343 4.2E-129 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c24750 840c3dfb19a8ffb5085f09e525cde1de 451 SUPERFAMILY SSF56935 65 451 1.02E-63 T 12-10-2018 MIM_c24750 840c3dfb19a8ffb5085f09e525cde1de 451 Pfam PF13609 Gram-negative porin 57 424 6.7E-50 T 12-10-2018 MIM_c24750 840c3dfb19a8ffb5085f09e525cde1de 451 PRINTS PR00184 Neisseria sp. porin signature 210 227 2.8E-9 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 MIM_c24750 840c3dfb19a8ffb5085f09e525cde1de 451 PRINTS PR00184 Neisseria sp. porin signature 400 424 2.8E-9 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 MIM_c24750 840c3dfb19a8ffb5085f09e525cde1de 451 PRINTS PR00184 Neisseria sp. porin signature 109 134 2.8E-9 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 MIM_c24750 840c3dfb19a8ffb5085f09e525cde1de 451 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 107 118 2.9E-5 T 12-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 MIM_c24750 840c3dfb19a8ffb5085f09e525cde1de 451 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 151 161 2.9E-5 T 12-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 MIM_c24750 840c3dfb19a8ffb5085f09e525cde1de 451 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 403 420 2.9E-5 T 12-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 MIM_c24750 840c3dfb19a8ffb5085f09e525cde1de 451 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 211 222 2.9E-5 T 12-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 MIM_c03920 27df485ae2d2825cf8f0c9ae1c376e95 595 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 65 586 1.1E-203 T 12-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 MIM_c03920 27df485ae2d2825cf8f0c9ae1c376e95 595 Pfam PF01019 Gamma-glutamyltranspeptidase 80 587 3.8E-188 T 12-10-2018 MIM_c03920 27df485ae2d2825cf8f0c9ae1c376e95 595 SUPERFAMILY SSF56235 57 595 1.91E-198 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MIM_c03920 27df485ae2d2825cf8f0c9ae1c376e95 595 Gene3D G3DSA:1.10.246.130 293 406 1.1E-42 T 12-10-2018 MIM_c03920 27df485ae2d2825cf8f0c9ae1c376e95 595 ProSitePatterns PS00462 Gamma-glutamyltranspeptidase signature. 407 431 - T 12-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 MIM_c03920 27df485ae2d2825cf8f0c9ae1c376e95 595 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 161 179 2.0E-82 T 12-10-2018 MIM_c03920 27df485ae2d2825cf8f0c9ae1c376e95 595 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 179 198 2.0E-82 T 12-10-2018 MIM_c03920 27df485ae2d2825cf8f0c9ae1c376e95 595 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 496 513 2.0E-82 T 12-10-2018 MIM_c03920 27df485ae2d2825cf8f0c9ae1c376e95 595 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 472 487 2.0E-82 T 12-10-2018 MIM_c03920 27df485ae2d2825cf8f0c9ae1c376e95 595 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 431 449 2.0E-82 T 12-10-2018 MIM_c03920 27df485ae2d2825cf8f0c9ae1c376e95 595 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 307 326 2.0E-82 T 12-10-2018 MIM_c03920 27df485ae2d2825cf8f0c9ae1c376e95 595 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 277 293 2.0E-82 T 12-10-2018 MIM_c03920 27df485ae2d2825cf8f0c9ae1c376e95 595 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 407 425 2.0E-82 T 12-10-2018 MIM_c03920 27df485ae2d2825cf8f0c9ae1c376e95 595 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 87 112 2.0E-82 T 12-10-2018 MIM_c03920 27df485ae2d2825cf8f0c9ae1c376e95 595 Gene3D G3DSA:3.60.20.40 407 595 2.4E-78 T 12-10-2018 MIM_c03210 a8cc763c14a3ff1e14759af777c484a3 907 Pfam PF01131 DNA topoisomerase 154 599 7.0E-113 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MIM_c03210 a8cc763c14a3ff1e14759af777c484a3 907 TIGRFAM TIGR01056 topB: DNA topoisomerase III 3 625 2.3E-164 T 12-10-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 MIM_c03210 a8cc763c14a3ff1e14759af777c484a3 907 Gene3D G3DSA:1.10.460.10 160 609 1.2E-157 T 12-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 MIM_c03210 a8cc763c14a3ff1e14759af777c484a3 907 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 316 331 - T 12-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 MIM_c03210 a8cc763c14a3ff1e14759af777c484a3 907 Gene3D G3DSA:3.40.50.140 3 153 7.3E-41 T 12-10-2018 MIM_c03210 a8cc763c14a3ff1e14759af777c484a3 907 Gene3D G3DSA:2.70.20.10 215 492 1.2E-157 T 12-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 MIM_c03210 a8cc763c14a3ff1e14759af777c484a3 907 Pfam PF13342 C-terminal repeat of topoisomerase 650 709 1.7E-20 T 12-10-2018 IPR025589 Topoisomerase C-terminal repeat MIM_c03210 a8cc763c14a3ff1e14759af777c484a3 907 Pfam PF13342 C-terminal repeat of topoisomerase 755 815 1.4E-18 T 12-10-2018 IPR025589 Topoisomerase C-terminal repeat MIM_c03210 a8cc763c14a3ff1e14759af777c484a3 907 SMART SM00493 3 126 3.4E-12 T 12-10-2018 IPR006171 TOPRIM domain MIM_c03210 a8cc763c14a3ff1e14759af777c484a3 907 Pfam PF01751 Toprim domain 4 132 7.1E-13 T 12-10-2018 IPR006171 TOPRIM domain MIM_c03210 a8cc763c14a3ff1e14759af777c484a3 907 SMART SM00437 279 561 1.6E-76 T 12-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 MIM_c03210 a8cc763c14a3ff1e14759af777c484a3 907 Gene3D G3DSA:1.10.290.10 288 423 1.2E-157 T 12-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 MIM_c03210 a8cc763c14a3ff1e14759af777c484a3 907 SMART SM00436 126 221 1.8E-22 T 12-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 MIM_c03210 a8cc763c14a3ff1e14759af777c484a3 907 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 409 425 2.0E-25 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MIM_c03210 a8cc763c14a3ff1e14759af777c484a3 907 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 100 113 2.0E-25 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MIM_c03210 a8cc763c14a3ff1e14759af777c484a3 907 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 322 331 2.0E-25 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MIM_c03210 a8cc763c14a3ff1e14759af777c484a3 907 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 191 209 2.0E-25 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MIM_c03210 a8cc763c14a3ff1e14759af777c484a3 907 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 524 538 2.0E-25 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MIM_c03210 a8cc763c14a3ff1e14759af777c484a3 907 SUPERFAMILY SSF56712 3 614 2.09E-166 T 12-10-2018 IPR023405 DNA topoisomerase, type IA, core domain MIM_c25480 0bbf8f659ad34ab1b4e9fcf13dd43191 275 Pfam PF01418 Helix-turn-helix domain, rpiR family 5 72 2.2E-13 T 12-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 MIM_c25480 0bbf8f659ad34ab1b4e9fcf13dd43191 275 Gene3D G3DSA:3.40.50.10490 105 275 7.1E-30 T 12-10-2018 MIM_c25480 0bbf8f659ad34ab1b4e9fcf13dd43191 275 Pfam PF01380 SIS domain 137 262 1.2E-17 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MIM_c25480 0bbf8f659ad34ab1b4e9fcf13dd43191 275 SUPERFAMILY SSF53697 107 272 1.29E-23 T 12-10-2018 MIM_c25480 0bbf8f659ad34ab1b4e9fcf13dd43191 275 Gene3D G3DSA:1.10.10.10 2 78 5.4E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c25480 0bbf8f659ad34ab1b4e9fcf13dd43191 275 SUPERFAMILY SSF46689 5 77 5.38E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c05710 40cddc312cc78098782c1d3acd2700df 258 SMART SM00382 27 207 4.8E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c05710 40cddc312cc78098782c1d3acd2700df 258 SUPERFAMILY SSF52540 3 213 5.32E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c05710 40cddc312cc78098782c1d3acd2700df 258 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c05710 40cddc312cc78098782c1d3acd2700df 258 Gene3D G3DSA:3.40.50.300 1 224 6.4E-60 T 12-10-2018 MIM_c05710 40cddc312cc78098782c1d3acd2700df 258 Pfam PF00005 ABC transporter 19 157 3.3E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c00610 be7d54e53b0031075ab551f2a056442e 216 Pfam PF13305 WHG domain 103 188 2.4E-9 T 12-10-2018 IPR025996 WHG domain MIM_c00610 be7d54e53b0031075ab551f2a056442e 216 Gene3D G3DSA:1.10.357.10 12 215 5.9E-45 T 12-10-2018 MIM_c00610 be7d54e53b0031075ab551f2a056442e 216 SUPERFAMILY SSF46689 15 87 5.67E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c00610 be7d54e53b0031075ab551f2a056442e 216 SUPERFAMILY SSF48498 100 209 3.89E-13 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MIM_c00610 be7d54e53b0031075ab551f2a056442e 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 70 1.3E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c00610 be7d54e53b0031075ab551f2a056442e 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 1.9E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c00610 be7d54e53b0031075ab551f2a056442e 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 1.9E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c12040 55b11d954fdcda4b6407447b224c6c95 398 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 218 2.1E-21 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MIM_c12040 55b11d954fdcda4b6407447b224c6c95 398 Gene3D G3DSA:1.20.140.10 235 398 3.2E-37 T 12-10-2018 MIM_c12040 55b11d954fdcda4b6407447b224c6c95 398 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 395 3.7E-19 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MIM_c12040 55b11d954fdcda4b6407447b224c6c95 398 Gene3D G3DSA:2.40.110.10 120 234 1.2E-38 T 12-10-2018 MIM_c12040 55b11d954fdcda4b6407447b224c6c95 398 SUPERFAMILY SSF56645 2 244 2.36E-78 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c12040 55b11d954fdcda4b6407447b224c6c95 398 Gene3D G3DSA:1.10.540.10 2 119 4.3E-29 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c12040 55b11d954fdcda4b6407447b224c6c95 398 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 120 1.9E-20 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c12040 55b11d954fdcda4b6407447b224c6c95 398 SUPERFAMILY SSF47203 231 398 1.02E-20 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c36160 e8c13964ddc4f0378a2bfec45981c048 299 Pfam PF03466 LysR substrate binding domain 95 289 4.0E-20 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c36160 e8c13964ddc4f0378a2bfec45981c048 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 5.4E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c36160 e8c13964ddc4f0378a2bfec45981c048 299 Gene3D G3DSA:3.40.190.10 164 264 4.9E-33 T 12-10-2018 MIM_c36160 e8c13964ddc4f0378a2bfec45981c048 299 Gene3D G3DSA:3.40.190.10 103 289 4.9E-33 T 12-10-2018 MIM_c36160 e8c13964ddc4f0378a2bfec45981c048 299 SUPERFAMILY SSF46785 4 87 4.84E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c36160 e8c13964ddc4f0378a2bfec45981c048 299 Gene3D G3DSA:1.10.10.10 7 94 1.9E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c36160 e8c13964ddc4f0378a2bfec45981c048 299 SUPERFAMILY SSF53850 87 292 1.54E-22 T 12-10-2018 MIM_c18620 e46e77e0cbb1efe1b2f959bb3021381f 459 SUPERFAMILY SSF51338 4 450 8.5E-21 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MIM_c18620 e46e77e0cbb1efe1b2f959bb3021381f 459 SUPERFAMILY SSF51556 60 379 3.54E-74 T 12-10-2018 IPR032466 Metal-dependent hydrolase MIM_c18620 e46e77e0cbb1efe1b2f959bb3021381f 459 Gene3D G3DSA:2.30.40.10 5 449 2.9E-112 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MIM_c18620 e46e77e0cbb1efe1b2f959bb3021381f 459 Gene3D G3DSA:3.20.20.140 58 420 2.9E-112 T 12-10-2018 MIM_c18620 e46e77e0cbb1efe1b2f959bb3021381f 459 Pfam PF01979 Amidohydrolase family 54 433 8.0E-20 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MIM_c13790 a871930a25c2dcd5e704f89e822e307b 301 Gene3D G3DSA:3.40.190.10 84 169 5.4E-12 T 12-10-2018 MIM_c13790 a871930a25c2dcd5e704f89e822e307b 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 4.9E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c13790 a871930a25c2dcd5e704f89e822e307b 301 SUPERFAMILY SSF46785 3 89 4.4E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c13790 a871930a25c2dcd5e704f89e822e307b 301 Pfam PF03466 LysR substrate binding domain 90 292 5.5E-28 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c13790 a871930a25c2dcd5e704f89e822e307b 301 Gene3D G3DSA:1.10.10.10 1 83 2.6E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c13790 a871930a25c2dcd5e704f89e822e307b 301 SUPERFAMILY SSF53850 91 295 4.03E-28 T 12-10-2018 MIM_c13790 a871930a25c2dcd5e704f89e822e307b 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 8.2E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c13790 a871930a25c2dcd5e704f89e822e307b 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 8.2E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c13790 a871930a25c2dcd5e704f89e822e307b 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 8.2E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c13790 a871930a25c2dcd5e704f89e822e307b 301 Gene3D G3DSA:3.40.190.10 176 263 5.2E-7 T 12-10-2018 MIM_c00590 6b9eec4f0236a65f548256e76efa89fe 371 Pfam PF00005 ABC transporter 28 171 4.9E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c00590 6b9eec4f0236a65f548256e76efa89fe 371 Gene3D G3DSA:2.40.50.940 232 355 7.9E-23 T 12-10-2018 MIM_c00590 6b9eec4f0236a65f548256e76efa89fe 371 SUPERFAMILY SSF52540 12 251 8.87E-86 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c00590 6b9eec4f0236a65f548256e76efa89fe 371 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c00590 6b9eec4f0236a65f548256e76efa89fe 371 Pfam PF08402 TOBE domain 283 344 3.2E-5 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 MIM_c00590 6b9eec4f0236a65f548256e76efa89fe 371 SUPERFAMILY SSF50331 247 363 2.38E-17 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MIM_c00590 6b9eec4f0236a65f548256e76efa89fe 371 Gene3D G3DSA:3.40.50.300 11 231 8.0E-68 T 12-10-2018 MIM_c00590 6b9eec4f0236a65f548256e76efa89fe 371 SMART SM00382 36 221 1.6E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c00590 6b9eec4f0236a65f548256e76efa89fe 371 Gene3D G3DSA:2.40.50.140 290 346 7.9E-23 T 12-10-2018 MIM_c17150 7c170d9daacb997d7374ae27bd395cc7 205 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 79 2.9E-15 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MIM_c17150 7c170d9daacb997d7374ae27bd395cc7 205 Pfam PF00043 Glutathione S-transferase, C-terminal domain 127 191 8.0E-11 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal MIM_c17150 7c170d9daacb997d7374ae27bd395cc7 205 SUPERFAMILY SSF47616 72 198 9.69E-27 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MIM_c17150 7c170d9daacb997d7374ae27bd395cc7 205 Gene3D G3DSA:1.20.1050.10 85 194 1.1E-25 T 12-10-2018 MIM_c17150 7c170d9daacb997d7374ae27bd395cc7 205 SUPERFAMILY SSF52833 1 84 1.14E-24 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c17150 7c170d9daacb997d7374ae27bd395cc7 205 Gene3D G3DSA:3.40.30.10 1 82 2.4E-23 T 12-10-2018 MIM_c40020 3a70b699f1fb6be0c4cfeb613013ddce 219 Gene3D G3DSA:1.10.3720.10 8 219 3.4E-43 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c40020 3a70b699f1fb6be0c4cfeb613013ddce 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 218 1.4E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c40020 3a70b699f1fb6be0c4cfeb613013ddce 219 SUPERFAMILY SSF161098 8 203 4.19E-40 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c04420 dc4d5e1c7f9821b6068c826f1743c94a 834 SUPERFAMILY SSF56935 157 833 5.72E-131 T 12-10-2018 MIM_c04420 dc4d5e1c7f9821b6068c826f1743c94a 834 Pfam PF07715 TonB-dependent Receptor Plug Domain 165 267 7.5E-16 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain MIM_c04420 dc4d5e1c7f9821b6068c826f1743c94a 834 Pfam PF00593 TonB dependent receptor 360 833 3.5E-54 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MIM_c04420 dc4d5e1c7f9821b6068c826f1743c94a 834 Pfam PF07660 Secretin and TonB N terminus short domain 72 121 8.3E-11 T 12-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MIM_c04420 dc4d5e1c7f9821b6068c826f1743c94a 834 Gene3D G3DSA:3.55.50.30 48 130 5.0E-22 T 12-10-2018 MIM_c04420 dc4d5e1c7f9821b6068c826f1743c94a 834 Gene3D G3DSA:2.170.130.10 141 275 3.8E-37 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MIM_c04420 dc4d5e1c7f9821b6068c826f1743c94a 834 Gene3D G3DSA:2.40.170.20 276 834 2.0E-162 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MIM_c04420 dc4d5e1c7f9821b6068c826f1743c94a 834 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 167 833 1.1E-105 T 12-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 MIM_c04420 dc4d5e1c7f9821b6068c826f1743c94a 834 SMART SM00965 72 122 7.9E-12 T 12-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MIM_c38620 8f0673330872ef6b90923630c2fea7a2 951 Hamap MF_00205 UvrABC system protein A [uvrA]. 1 946 22.13 T 12-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 MIM_c38620 8f0673330872ef6b90923630c2fea7a2 951 Gene3D G3DSA:1.20.1580.10 699 836 1.5E-140 T 12-10-2018 MIM_c38620 8f0673330872ef6b90923630c2fea7a2 951 Gene3D G3DSA:1.10.8.280 285 401 6.4E-246 T 12-10-2018 MIM_c38620 8f0673330872ef6b90923630c2fea7a2 951 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 4 931 0.0 T 12-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 MIM_c38620 8f0673330872ef6b90923630c2fea7a2 951 Gene3D G3DSA:3.40.50.300 620 942 1.5E-140 T 12-10-2018 MIM_c38620 8f0673330872ef6b90923630c2fea7a2 951 ProSitePatterns PS00211 ABC transporters family signature. 836 850 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c38620 8f0673330872ef6b90923630c2fea7a2 951 Gene3D G3DSA:3.40.50.300 6 602 6.4E-246 T 12-10-2018 MIM_c38620 8f0673330872ef6b90923630c2fea7a2 951 SUPERFAMILY SSF52540 628 919 4.06E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c38620 8f0673330872ef6b90923630c2fea7a2 951 Gene3D G3DSA:1.20.1580.10 90 499 6.4E-246 T 12-10-2018 MIM_c38620 8f0673330872ef6b90923630c2fea7a2 951 ProSitePatterns PS00211 ABC transporters family signature. 494 508 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c38620 8f0673330872ef6b90923630c2fea7a2 951 SUPERFAMILY SSF52540 1 576 1.71E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c38620 8f0673330872ef6b90923630c2fea7a2 951 Gene3D G3DSA:3.30.190.20 130 242 6.4E-246 T 12-10-2018 MIM_c37370 8bdf07b255165e0ac7090ca2e81dbbe9 250 Gene3D G3DSA:1.10.10.60 156 249 2.7E-12 T 12-10-2018 MIM_c37370 8bdf07b255165e0ac7090ca2e81dbbe9 250 SUPERFAMILY SSF46689 161 204 3.19E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c37370 8bdf07b255165e0ac7090ca2e81dbbe9 250 SMART SM00342 170 243 7.4E-4 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c04580 67c8a4cf604cc818346c09033389ca94 258 Pfam PF02104 SURF1 family 19 234 2.8E-27 T 12-10-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c15750 82052c4630b56edebd22d545e728f301 316 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 56 63 - T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MIM_c15750 82052c4630b56edebd22d545e728f301 316 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 10 308 78.521 T 12-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 MIM_c15750 82052c4630b56edebd22d545e728f301 316 SUPERFAMILY SSF53671 9 307 3.77E-103 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MIM_c15750 82052c4630b56edebd22d545e728f301 316 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 11 151 3.1E-49 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 MIM_c15750 82052c4630b56edebd22d545e728f301 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 1.6E-27 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MIM_c15750 82052c4630b56edebd22d545e728f301 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 56 75 1.6E-27 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MIM_c15750 82052c4630b56edebd22d545e728f301 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 272 295 1.6E-27 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MIM_c15750 82052c4630b56edebd22d545e728f301 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 138 149 1.6E-27 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MIM_c15750 82052c4630b56edebd22d545e728f301 316 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 11 307 5.9E-116 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MIM_c15750 82052c4630b56edebd22d545e728f301 316 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 157 305 7.3E-49 T 12-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 MIM_c15750 82052c4630b56edebd22d545e728f301 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 87 100 4.8E-30 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MIM_c15750 82052c4630b56edebd22d545e728f301 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 127 141 4.8E-30 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MIM_c15750 82052c4630b56edebd22d545e728f301 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 54 68 4.8E-30 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MIM_c15750 82052c4630b56edebd22d545e728f301 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 224 234 4.8E-30 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MIM_c15750 82052c4630b56edebd22d545e728f301 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 286 297 4.8E-30 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MIM_c15750 82052c4630b56edebd22d545e728f301 316 Gene3D G3DSA:3.40.50.1370 141 303 3.9E-114 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MIM_c15750 82052c4630b56edebd22d545e728f301 316 Gene3D G3DSA:3.40.50.1370 11 140 3.9E-114 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MIM_c33110 574bf2fe9a39aaf279b428e812683af6 249 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 62 248 2.3E-52 T 12-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 MIM_c33110 574bf2fe9a39aaf279b428e812683af6 249 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 37 249 29.837 T 12-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 MIM_c33110 574bf2fe9a39aaf279b428e812683af6 249 SUPERFAMILY SSF53335 29 248 3.5E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c33110 574bf2fe9a39aaf279b428e812683af6 249 Gene3D G3DSA:3.40.50.150 43 249 2.5E-64 T 12-10-2018 MIM_c33110 574bf2fe9a39aaf279b428e812683af6 249 Pfam PF02390 Putative methyltransferase 77 242 8.5E-53 T 12-10-2018 MIM_c09720 d2ad2fb076046a9079a4dd0bca9a282b 932 Gene3D G3DSA:3.40.1190.10 101 336 1.7E-69 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MIM_c09720 d2ad2fb076046a9079a4dd0bca9a282b 932 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 485 920 31.644 T 12-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MIM_c09720 d2ad2fb076046a9079a4dd0bca9a282b 932 SUPERFAMILY SSF63418 18 100 1.96E-16 T 12-10-2018 IPR035911 MurE/MurF, N-terminal MIM_c09720 d2ad2fb076046a9079a4dd0bca9a282b 932 Gene3D G3DSA:3.90.190.20 344 494 4.6E-48 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MIM_c09720 d2ad2fb076046a9079a4dd0bca9a282b 932 Pfam PF02875 Mur ligase family, glutamate ligase domain 333 427 9.1E-20 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 MIM_c09720 d2ad2fb076046a9079a4dd0bca9a282b 932 Pfam PF02875 Mur ligase family, glutamate ligase domain 789 870 1.8E-13 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 MIM_c09720 d2ad2fb076046a9079a4dd0bca9a282b 932 Gene3D G3DSA:3.40.1390.10 4 100 2.0E-22 T 12-10-2018 MIM_c09720 d2ad2fb076046a9079a4dd0bca9a282b 932 SUPERFAMILY SSF53244 789 919 2.75E-35 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MIM_c09720 d2ad2fb076046a9079a4dd0bca9a282b 932 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 502 919 4.9E-128 T 12-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MIM_c09720 d2ad2fb076046a9079a4dd0bca9a282b 932 Gene3D G3DSA:3.40.1190.10 555 786 2.3E-73 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MIM_c09720 d2ad2fb076046a9079a4dd0bca9a282b 932 SUPERFAMILY SSF53244 333 488 1.44E-38 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MIM_c09720 d2ad2fb076046a9079a4dd0bca9a282b 932 SUPERFAMILY SSF63418 499 571 5.62E-20 T 12-10-2018 IPR035911 MurE/MurF, N-terminal MIM_c09720 d2ad2fb076046a9079a4dd0bca9a282b 932 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 492 30.998 T 12-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 MIM_c09720 d2ad2fb076046a9079a4dd0bca9a282b 932 Pfam PF08245 Mur ligase middle domain 110 312 3.3E-42 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MIM_c09720 d2ad2fb076046a9079a4dd0bca9a282b 932 Pfam PF08245 Mur ligase middle domain 579 769 8.9E-43 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MIM_c09720 d2ad2fb076046a9079a4dd0bca9a282b 932 SUPERFAMILY SSF53623 574 787 8.37E-52 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MIM_c09720 d2ad2fb076046a9079a4dd0bca9a282b 932 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 19 486 5.6E-136 T 12-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 MIM_c09720 d2ad2fb076046a9079a4dd0bca9a282b 932 Gene3D G3DSA:3.40.1390.10 495 554 3.4E-18 T 12-10-2018 MIM_c09720 d2ad2fb076046a9079a4dd0bca9a282b 932 Pfam PF01225 Mur ligase family, catalytic domain 500 544 1.2E-7 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MIM_c09720 d2ad2fb076046a9079a4dd0bca9a282b 932 Pfam PF01225 Mur ligase family, catalytic domain 21 98 3.5E-10 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MIM_c09720 d2ad2fb076046a9079a4dd0bca9a282b 932 SUPERFAMILY SSF53623 101 328 4.84E-64 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MIM_c09720 d2ad2fb076046a9079a4dd0bca9a282b 932 Gene3D G3DSA:3.90.190.20 788 923 1.1E-40 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MIM_c27690 6c3b5bf3602bdf0635e05bdae5db351f 395 Gene3D G3DSA:3.40.50.20 9 116 5.1E-38 T 12-10-2018 MIM_c27690 6c3b5bf3602bdf0635e05bdae5db351f 395 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 16 374 40.426 T 12-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 MIM_c27690 6c3b5bf3602bdf0635e05bdae5db351f 395 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 17 379 3.4E-117 T 12-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 MIM_c27690 6c3b5bf3602bdf0635e05bdae5db351f 395 Pfam PF02222 ATP-grasp domain 122 290 2.0E-47 T 12-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type MIM_c27690 6c3b5bf3602bdf0635e05bdae5db351f 395 SUPERFAMILY SSF51246 314 386 4.16E-17 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MIM_c27690 6c3b5bf3602bdf0635e05bdae5db351f 395 SUPERFAMILY SSF52440 15 109 3.74E-23 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MIM_c27690 6c3b5bf3602bdf0635e05bdae5db351f 395 Gene3D G3DSA:3.30.470.20 190 390 1.4E-77 T 12-10-2018 MIM_c27690 6c3b5bf3602bdf0635e05bdae5db351f 395 SUPERFAMILY SSF56059 112 310 1.4E-54 T 12-10-2018 MIM_c27690 6c3b5bf3602bdf0635e05bdae5db351f 395 Gene3D G3DSA:3.30.1490.20 117 189 1.4E-19 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MIM_c30040 c782924bce509d20c16da33295817434 229 Pfam PF13410 Glutathione S-transferase, C-terminal domain 127 200 7.6E-7 T 12-10-2018 MIM_c30040 c782924bce509d20c16da33295817434 229 Gene3D G3DSA:3.40.30.10 7 198 5.9E-54 T 12-10-2018 MIM_c30040 c782924bce509d20c16da33295817434 229 Pfam PF13417 Glutathione S-transferase, N-terminal domain 10 82 1.1E-13 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MIM_c30040 c782924bce509d20c16da33295817434 229 SUPERFAMILY SSF52833 2 82 4.03E-16 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c30040 c782924bce509d20c16da33295817434 229 Gene3D G3DSA:1.20.1050.10 85 194 5.9E-54 T 12-10-2018 MIM_c30040 c782924bce509d20c16da33295817434 229 SUPERFAMILY SSF47616 83 200 1.56E-16 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MIM_c07460 1992b5ae33a42658f40d115eff20c308 295 Pfam PF00119 ATP synthase A chain 42 288 7.7E-56 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07460 1992b5ae33a42658f40d115eff20c308 295 Gene3D G3DSA:1.20.120.220 93 295 3.6E-49 T 12-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07460 1992b5ae33a42658f40d115eff20c308 295 ProSitePatterns PS00449 ATP synthase a subunit signature. 218 227 - T 12-10-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07460 1992b5ae33a42658f40d115eff20c308 295 Hamap MF_01393 ATP synthase subunit a [atpB]. 14 295 14.276 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07460 1992b5ae33a42658f40d115eff20c308 295 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 37 290 2.9E-40 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07460 1992b5ae33a42658f40d115eff20c308 295 SUPERFAMILY SSF81336 97 288 8.24E-36 T 12-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c04770 00d9a52853d5e7481f63879b0a200464 181 Pfam PF02470 MlaD protein 37 115 3.0E-20 T 12-10-2018 IPR003399 Mce/MlaD MIM_c04770 00d9a52853d5e7481f63879b0a200464 181 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 2 146 2.3E-56 T 12-10-2018 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 MIM_c20690 6137b46b6268444c58501310588efa77 256 Gene3D G3DSA:3.90.226.10 1 193 2.4E-63 T 12-10-2018 MIM_c20690 6137b46b6268444c58501310588efa77 256 SUPERFAMILY SSF52096 3 255 7.83E-77 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c20690 6137b46b6268444c58501310588efa77 256 Gene3D G3DSA:1.10.12.10 198 255 2.4E-15 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MIM_c20690 6137b46b6268444c58501310588efa77 256 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 255 9.1E-57 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c32880 e7d952ffe3188c01baf3ff221f5c90b3 228 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 185 7.9E-27 T 12-10-2018 MIM_c32880 e7d952ffe3188c01baf3ff221f5c90b3 228 SUPERFAMILY SSF56784 7 221 4.66E-53 T 12-10-2018 IPR036412 HAD-like superfamily MIM_c32880 e7d952ffe3188c01baf3ff221f5c90b3 228 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 47 185 4.4E-19 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MIM_c32880 e7d952ffe3188c01baf3ff221f5c90b3 228 Gene3D G3DSA:3.40.50.1000 9 205 2.3E-61 T 12-10-2018 IPR023214 HAD superfamily MIM_c32880 e7d952ffe3188c01baf3ff221f5c90b3 228 Gene3D G3DSA:1.10.150.240 21 87 2.3E-61 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MIM_c06450 ee03c82db5deb6ce9527966f8048e111 499 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 35 441 1.3E-117 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MIM_c06450 ee03c82db5deb6ce9527966f8048e111 499 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 7 493 5.8E-210 T 12-10-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 MIM_c06450 ee03c82db5deb6ce9527966f8048e111 499 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 423 443 - T 12-10-2018 IPR018212 Sodium/solute symporter, conserved site MIM_c06450 ee03c82db5deb6ce9527966f8048e111 499 Pfam PF00474 Sodium:solute symporter family 35 441 7.3E-127 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MIM_c06450 ee03c82db5deb6ce9527966f8048e111 499 Gene3D G3DSA:1.20.1730.10 21 495 3.7E-93 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily MIM_c32920 b9e941ba2a79a173c6f63126db49771b 348 Pfam PF01571 Aminomethyltransferase folate-binding domain 1 238 2.0E-84 T 12-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain MIM_c32920 b9e941ba2a79a173c6f63126db49771b 348 Gene3D G3DSA:2.40.30.110 261 347 5.1E-27 T 12-10-2018 MIM_c32920 b9e941ba2a79a173c6f63126db49771b 348 Gene3D G3DSA:3.30.70.1400 34 123 1.9E-79 T 12-10-2018 MIM_c32920 b9e941ba2a79a173c6f63126db49771b 348 Gene3D G3DSA:4.10.1250.10 217 260 1.4E-19 T 12-10-2018 MIM_c32920 b9e941ba2a79a173c6f63126db49771b 348 SUPERFAMILY SSF101790 260 341 2.13E-20 T 12-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal MIM_c32920 b9e941ba2a79a173c6f63126db49771b 348 PIRSF PIRSF006487 1 346 7.8E-80 T 12-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 MIM_c32920 b9e941ba2a79a173c6f63126db49771b 348 SUPERFAMILY SSF103025 1 257 1.79E-85 T 12-10-2018 MIM_c32920 b9e941ba2a79a173c6f63126db49771b 348 Gene3D G3DSA:3.30.1360.120 2 216 1.9E-79 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 MIM_c32920 b9e941ba2a79a173c6f63126db49771b 348 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 248 333 9.6E-13 T 12-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MIM_c32920 b9e941ba2a79a173c6f63126db49771b 348 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 1 339 7.0E-116 T 12-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 MIM_c14090 4961a596a31858f9dc45793af695c48f 553 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 263 277 - T 12-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 MIM_c14090 4961a596a31858f9dc45793af695c48f 553 Gene3D G3DSA:3.30.70.580 226 385 1.2E-46 T 12-10-2018 MIM_c14090 4961a596a31858f9dc45793af695c48f 553 SUPERFAMILY SSF55174 163 254 1.41E-15 T 12-10-2018 MIM_c14090 4961a596a31858f9dc45793af695c48f 553 Gene3D G3DSA:3.30.70.1560 287 377 1.2E-46 T 12-10-2018 MIM_c14090 4961a596a31858f9dc45793af695c48f 553 SUPERFAMILY SSF55120 223 391 4.64E-41 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MIM_c14090 4961a596a31858f9dc45793af695c48f 553 SMART SM00363 162 222 2.1E-8 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c14090 4961a596a31858f9dc45793af695c48f 553 Pfam PF01479 S4 domain 164 207 2.1E-8 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c14090 4961a596a31858f9dc45793af695c48f 553 Pfam PF00849 RNA pseudouridylate synthase 225 358 2.8E-15 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MIM_c14090 4961a596a31858f9dc45793af695c48f 553 Gene3D G3DSA:3.10.290.10 158 216 5.5E-20 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MIM_c14090 4961a596a31858f9dc45793af695c48f 553 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 229 389 2.1E-52 T 12-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 MIM_c23730 f018742b77d0d83c87c7ed00327ba501 509 Gene3D G3DSA:3.40.220.10 1 179 1.2E-29 T 12-10-2018 MIM_c23730 f018742b77d0d83c87c7ed00327ba501 509 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 4 504 36.48 T 12-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 MIM_c23730 f018742b77d0d83c87c7ed00327ba501 509 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 21 143 1.0E-14 T 12-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MIM_c23730 f018742b77d0d83c87c7ed00327ba501 509 PRINTS PR00481 Cytosol aminopeptidase signature 379 394 7.3E-55 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MIM_c23730 f018742b77d0d83c87c7ed00327ba501 509 PRINTS PR00481 Cytosol aminopeptidase signature 270 287 7.3E-55 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MIM_c23730 f018742b77d0d83c87c7ed00327ba501 509 PRINTS PR00481 Cytosol aminopeptidase signature 329 350 7.3E-55 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MIM_c23730 f018742b77d0d83c87c7ed00327ba501 509 PRINTS PR00481 Cytosol aminopeptidase signature 351 371 7.3E-55 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MIM_c23730 f018742b77d0d83c87c7ed00327ba501 509 PRINTS PR00481 Cytosol aminopeptidase signature 292 313 7.3E-55 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MIM_c23730 f018742b77d0d83c87c7ed00327ba501 509 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 355 362 - T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MIM_c23730 f018742b77d0d83c87c7ed00327ba501 509 Gene3D G3DSA:3.40.630.10 180 504 8.0E-137 T 12-10-2018 MIM_c23730 f018742b77d0d83c87c7ed00327ba501 509 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 186 495 9.9E-123 T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MIM_c23730 f018742b77d0d83c87c7ed00327ba501 509 SUPERFAMILY SSF52949 2 183 2.12E-27 T 12-10-2018 MIM_c23730 f018742b77d0d83c87c7ed00327ba501 509 SUPERFAMILY SSF53187 179 502 2.35E-120 T 12-10-2018 MIM_c01420 9476dbd0d2bcbe0253953d3ac18c0e7c 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 319 6.9E-60 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c01420 9476dbd0d2bcbe0253953d3ac18c0e7c 331 Gene3D G3DSA:3.40.190.150 32 318 8.9E-89 T 12-10-2018 MIM_c01420 9476dbd0d2bcbe0253953d3ac18c0e7c 331 SUPERFAMILY SSF53850 100 286 4.7E-7 T 12-10-2018 MIM_c01420 9476dbd0d2bcbe0253953d3ac18c0e7c 331 Gene3D G3DSA:3.40.190.10 129 253 8.9E-89 T 12-10-2018 MIM_c01420 9476dbd0d2bcbe0253953d3ac18c0e7c 331 PIRSF PIRSF017082 1 327 8.3E-67 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c36310 a57122c63f754ce260e245dae5ebcbe8 430 Gene3D G3DSA:3.30.70.360 223 332 5.9E-108 T 12-10-2018 MIM_c36310 a57122c63f754ce260e245dae5ebcbe8 430 Pfam PF01546 Peptidase family M20/M25/M40 119 420 3.3E-27 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 MIM_c36310 a57122c63f754ce260e245dae5ebcbe8 430 Pfam PF07687 Peptidase dimerisation domain 221 319 6.4E-16 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain MIM_c36310 a57122c63f754ce260e245dae5ebcbe8 430 PIRSF PIRSF037238 31 424 5.8E-101 T 12-10-2018 IPR017150 Peptidase M20, glutamate carboxypeptidase MIM_c36310 a57122c63f754ce260e245dae5ebcbe8 430 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 117 126 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 MIM_c36310 a57122c63f754ce260e245dae5ebcbe8 430 Gene3D G3DSA:3.40.630.10 48 412 5.9E-108 T 12-10-2018 MIM_c36310 a57122c63f754ce260e245dae5ebcbe8 430 SUPERFAMILY SSF53187 33 423 1.26E-50 T 12-10-2018 MIM_c36310 a57122c63f754ce260e245dae5ebcbe8 430 SUPERFAMILY SSF55031 224 335 2.75E-19 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain MIM_c03800 ae9a3b04642bcdfcfdada29dd10ce012 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 4.8E-41 T 12-10-2018 MIM_c03800 ae9a3b04642bcdfcfdada29dd10ce012 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 433 453 4.8E-41 T 12-10-2018 MIM_c03800 ae9a3b04642bcdfcfdada29dd10ce012 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 4.8E-41 T 12-10-2018 MIM_c03800 ae9a3b04642bcdfcfdada29dd10ce012 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 4.8E-41 T 12-10-2018 MIM_c03800 ae9a3b04642bcdfcfdada29dd10ce012 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 306 313 4.8E-41 T 12-10-2018 MIM_c03800 ae9a3b04642bcdfcfdada29dd10ce012 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 411 426 4.8E-41 T 12-10-2018 MIM_c03800 ae9a3b04642bcdfcfdada29dd10ce012 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 138 147 4.8E-41 T 12-10-2018 MIM_c03800 ae9a3b04642bcdfcfdada29dd10ce012 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 262 276 4.8E-41 T 12-10-2018 MIM_c03800 ae9a3b04642bcdfcfdada29dd10ce012 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 343 364 4.8E-41 T 12-10-2018 MIM_c03800 ae9a3b04642bcdfcfdada29dd10ce012 482 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 326 3.3E-41 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MIM_c03800 ae9a3b04642bcdfcfdada29dd10ce012 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 1.9E-22 T 12-10-2018 MIM_c03800 ae9a3b04642bcdfcfdada29dd10ce012 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 277 1.9E-22 T 12-10-2018 MIM_c03800 ae9a3b04642bcdfcfdada29dd10ce012 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 291 313 1.9E-22 T 12-10-2018 MIM_c03800 ae9a3b04642bcdfcfdada29dd10ce012 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.9E-22 T 12-10-2018 MIM_c03800 ae9a3b04642bcdfcfdada29dd10ce012 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 1.9E-22 T 12-10-2018 MIM_c03800 ae9a3b04642bcdfcfdada29dd10ce012 482 SUPERFAMILY SSF51905 1 364 4.38E-40 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c03800 ae9a3b04642bcdfcfdada29dd10ce012 482 Gene3D G3DSA:3.50.50.60 147 268 4.0E-95 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c03800 ae9a3b04642bcdfcfdada29dd10ce012 482 SUPERFAMILY SSF55424 349 466 1.31E-26 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MIM_c03800 ae9a3b04642bcdfcfdada29dd10ce012 482 Gene3D G3DSA:1.10.287.990 37 107 4.0E-95 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c03800 ae9a3b04642bcdfcfdada29dd10ce012 482 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 350 458 5.6E-18 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MIM_c03800 ae9a3b04642bcdfcfdada29dd10ce012 482 Gene3D G3DSA:3.30.390.30 346 469 1.4E-42 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MIM_c03800 ae9a3b04642bcdfcfdada29dd10ce012 482 PIRSF PIRSF000350 1 466 1.2E-61 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 MIM_c03800 ae9a3b04642bcdfcfdada29dd10ce012 482 Gene3D G3DSA:3.50.50.60 7 329 4.0E-95 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c11750 79ec112a9176931ddb39c23f1938e893 464 Pfam PF00890 FAD binding domain 8 431 6.0E-39 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MIM_c11750 79ec112a9176931ddb39c23f1938e893 464 Gene3D G3DSA:3.50.50.60 7 458 4.1E-94 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c11750 79ec112a9176931ddb39c23f1938e893 464 SUPERFAMILY SSF51905 5 461 6.35E-40 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c11750 79ec112a9176931ddb39c23f1938e893 464 Gene3D G3DSA:3.90.700.10 238 399 4.1E-94 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 MIM_c11750 79ec112a9176931ddb39c23f1938e893 464 SUPERFAMILY SSF56425 266 403 9.77E-24 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 MIM_c11750 79ec112a9176931ddb39c23f1938e893 464 TIGRFAM TIGR02485 CobZ_N-term: precorrin 3B synthase CobZ 7 462 1.1E-181 T 12-10-2018 IPR012831 Precorrin 3B synthase CobZ MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 Gene3D G3DSA:3.55.50.10 107 197 8.9E-99 T 12-10-2018 MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 SUPERFAMILY SSF69349 456 626 1.8E-33 T 12-10-2018 MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 SUPERFAMILY SSF69279 196 378 1.7E-30 T 12-10-2018 MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1739 1816 3.8E-26 T 12-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 Gene3D G3DSA:2.30.110.50 29 341 8.9E-99 T 12-10-2018 MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 Gene3D G3DSA:3.90.930.1 993 1087 2.1E-5 T 12-10-2018 MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 Gene3D G3DSA:3.90.930.1 1088 1232 1.5E-12 T 12-10-2018 MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 Pfam PF03527 RHS protein 1714 1745 8.8E-12 T 12-10-2018 IPR001826 RHS protein MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 19 538 1.0E-174 T 12-10-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 Pfam PF05954 Phage late control gene D protein (GPD) 37 339 1.2E-82 T 12-10-2018 MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 SUPERFAMILY SSF69255 378 466 4.18E-32 T 12-10-2018 MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 Gene3D G3DSA:3.30.1920.30 233 295 8.9E-99 T 12-10-2018 MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 SUPERFAMILY SSF69279 21 192 5.53E-49 T 12-10-2018 MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 Gene3D G3DSA:2.40.50.230 369 470 2.3E-41 T 12-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 Gene3D G3DSA:2.180.10.10 1261 1386 2.1E-9 T 12-10-2018 MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 Gene3D G3DSA:2.180.10.10 1463 1816 1.3E-40 T 12-10-2018 MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1625 1655 6.5E-9 T 12-10-2018 IPR006530 YD repeat MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1124 1162 3.0E-5 T 12-10-2018 IPR006530 YD repeat MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1248 1288 1.3E-8 T 12-10-2018 IPR006530 YD repeat MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1081 1122 1.2E-11 T 12-10-2018 IPR006530 YD repeat MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 33 520 3.5E-136 T 12-10-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 Pfam PF05593 RHS Repeat 1234 1264 1.9E-6 T 12-10-2018 IPR031325 RHS repeat MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 Pfam PF05593 RHS Repeat 1143 1179 2.5E-6 T 12-10-2018 IPR031325 RHS repeat MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 Pfam PF05593 RHS Repeat 1102 1137 1.1E-6 T 12-10-2018 IPR031325 RHS repeat MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 Pfam PF05593 RHS Repeat 1625 1653 1.5E-4 T 12-10-2018 IPR031325 RHS repeat MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 Pfam PF05593 RHS Repeat 1061 1096 1.8E-6 T 12-10-2018 IPR031325 RHS repeat MIM_c33950 a88608562cd0f0a4dcb11a1aca841a7d 1990 Pfam PF05593 RHS Repeat 920 955 1.3E-4 T 12-10-2018 IPR031325 RHS repeat MIM_c26260 6be3825e766443878e7be2f0a2d766a9 161 Pfam PF04073 Aminoacyl-tRNA editing domain 37 150 3.8E-21 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MIM_c26260 6be3825e766443878e7be2f0a2d766a9 161 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 10 158 3.5E-46 T 12-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC MIM_c26260 6be3825e766443878e7be2f0a2d766a9 161 Gene3D G3DSA:3.90.960.10 2 161 6.4E-45 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 MIM_c26260 6be3825e766443878e7be2f0a2d766a9 161 PIRSF PIRSF006181 5 161 3.3E-43 T 12-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC MIM_c26260 6be3825e766443878e7be2f0a2d766a9 161 SUPERFAMILY SSF55826 10 159 1.15E-39 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 MIM_c29010 b5a0ddb46df1a53f372b0cb23abb9861 1184 Pfam PF00005 ABC transporter 959 1108 1.1E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c29010 b5a0ddb46df1a53f372b0cb23abb9861 1184 Pfam PF00005 ABC transporter 352 499 5.9E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c29010 b5a0ddb46df1a53f372b0cb23abb9861 1184 SMART SM00382 968 1160 1.8E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c29010 b5a0ddb46df1a53f372b0cb23abb9861 1184 SMART SM00382 360 546 1.0E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c29010 b5a0ddb46df1a53f372b0cb23abb9861 1184 SUPERFAMILY SSF90123 7 299 2.62E-45 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MIM_c29010 b5a0ddb46df1a53f372b0cb23abb9861 1184 SUPERFAMILY SSF90123 617 925 2.35E-50 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MIM_c29010 b5a0ddb46df1a53f372b0cb23abb9861 1184 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c29010 b5a0ddb46df1a53f372b0cb23abb9861 1184 SUPERFAMILY SSF52540 326 570 2.66E-85 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c29010 b5a0ddb46df1a53f372b0cb23abb9861 1184 Gene3D G3DSA:1.20.1560.10 614 923 3.1E-48 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MIM_c29010 b5a0ddb46df1a53f372b0cb23abb9861 1184 Gene3D G3DSA:1.20.1560.10 5 316 1.3E-40 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MIM_c29010 b5a0ddb46df1a53f372b0cb23abb9861 1184 ProSitePatterns PS00211 ABC transporters family signature. 1080 1094 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c29010 b5a0ddb46df1a53f372b0cb23abb9861 1184 SUPERFAMILY SSF52540 935 1178 2.85E-88 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c29010 b5a0ddb46df1a53f372b0cb23abb9861 1184 Gene3D G3DSA:3.40.50.300 936 1183 1.2E-86 T 12-10-2018 MIM_c29010 b5a0ddb46df1a53f372b0cb23abb9861 1184 Gene3D G3DSA:3.40.50.300 329 584 2.1E-87 T 12-10-2018 MIM_c29010 b5a0ddb46df1a53f372b0cb23abb9861 1184 Pfam PF00664 ABC transporter transmembrane region 28 280 6.3E-22 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MIM_c29010 b5a0ddb46df1a53f372b0cb23abb9861 1184 Pfam PF00664 ABC transporter transmembrane region 630 886 3.0E-18 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MIM_c37090 cf084f67cb6ca8e996c9d80296346098 315 Pfam PF03466 LysR substrate binding domain 94 304 3.1E-20 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c37090 cf084f67cb6ca8e996c9d80296346098 315 Gene3D G3DSA:1.10.10.10 1 88 7.7E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c37090 cf084f67cb6ca8e996c9d80296346098 315 Gene3D G3DSA:3.40.190.10 94 298 2.4E-52 T 12-10-2018 MIM_c37090 cf084f67cb6ca8e996c9d80296346098 315 SUPERFAMILY SSF46785 3 76 2.79E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c37090 cf084f67cb6ca8e996c9d80296346098 315 Gene3D G3DSA:3.40.190.10 169 275 2.4E-52 T 12-10-2018 MIM_c37090 cf084f67cb6ca8e996c9d80296346098 315 SUPERFAMILY SSF53850 93 303 1.99E-31 T 12-10-2018 MIM_c37090 cf084f67cb6ca8e996c9d80296346098 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 4.3E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c15370 d22a426f5324c20f9897f2ab2d11f7c5 302 Gene3D G3DSA:1.10.760.10 178 299 3.1E-41 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c15370 d22a426f5324c20f9897f2ab2d11f7c5 302 SUPERFAMILY SSF46626 86 169 4.71E-22 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c15370 d22a426f5324c20f9897f2ab2d11f7c5 302 Gene3D G3DSA:1.10.760.10 47 173 1.2E-37 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c15370 d22a426f5324c20f9897f2ab2d11f7c5 302 SUPERFAMILY SSF46626 178 285 1.75E-17 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c15370 d22a426f5324c20f9897f2ab2d11f7c5 302 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 189 275 2.8E-7 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c29600 ccfef3ffda7f5d1ab9793d943d46e42d 223 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 8 216 22.461 T 12-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MIM_c29600 ccfef3ffda7f5d1ab9793d943d46e42d 223 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 10 209 1.1E-47 T 12-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MIM_c29600 ccfef3ffda7f5d1ab9793d943d46e42d 223 Pfam PF02581 Thiamine monophosphate synthase 10 197 3.4E-46 T 12-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MIM_c29600 ccfef3ffda7f5d1ab9793d943d46e42d 223 Gene3D G3DSA:3.20.20.70 5 217 2.6E-52 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c29600 ccfef3ffda7f5d1ab9793d943d46e42d 223 SUPERFAMILY SSF51391 7 216 3.27E-52 T 12-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MIM_c28030 f611969e5ef181bd0e7e2c32f78e64b9 1183 Gene3D G3DSA:1.10.150.870 938 1001 1.5E-6 T 12-10-2018 MIM_c28030 f611969e5ef181bd0e7e2c32f78e64b9 1183 Pfam PF02811 PHP domain 20 218 1.5E-7 T 12-10-2018 IPR004013 PHP domain GO:0003824 MIM_c28030 f611969e5ef181bd0e7e2c32f78e64b9 1183 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 163 898 1.9E-146 T 12-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MIM_c28030 f611969e5ef181bd0e7e2c32f78e64b9 1183 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 17 1183 13.48 T 12-10-2018 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MIM_c28030 f611969e5ef181bd0e7e2c32f78e64b9 1183 SUPERFAMILY SSF81585 947 998 4.18E-6 T 12-10-2018 MIM_c28030 f611969e5ef181bd0e7e2c32f78e64b9 1183 SMART SM00481 18 172 0.001 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal MIM_c28030 f611969e5ef181bd0e7e2c32f78e64b9 1183 Pfam PF14579 Helix-hairpin-helix motif 886 1014 2.6E-22 T 12-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MIM_c28030 f611969e5ef181bd0e7e2c32f78e64b9 1183 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 388 811 2.8E-146 T 12-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MIM_c08750 29a3a60ddbf3f6a9e1a01086363447ff 447 SUPERFAMILY SSF118215 22 415 1.29E-118 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MIM_c08750 29a3a60ddbf3f6a9e1a01086363447ff 447 PRINTS PR00173 Glutamate-aspartate symporter signature 340 359 9.1E-31 T 12-10-2018 MIM_c08750 29a3a60ddbf3f6a9e1a01086363447ff 447 PRINTS PR00173 Glutamate-aspartate symporter signature 16 36 9.1E-31 T 12-10-2018 MIM_c08750 29a3a60ddbf3f6a9e1a01086363447ff 447 PRINTS PR00173 Glutamate-aspartate symporter signature 87 112 9.1E-31 T 12-10-2018 MIM_c08750 29a3a60ddbf3f6a9e1a01086363447ff 447 PRINTS PR00173 Glutamate-aspartate symporter signature 57 77 9.1E-31 T 12-10-2018 MIM_c08750 29a3a60ddbf3f6a9e1a01086363447ff 447 PRINTS PR00173 Glutamate-aspartate symporter signature 158 180 9.1E-31 T 12-10-2018 MIM_c08750 29a3a60ddbf3f6a9e1a01086363447ff 447 PRINTS PR00173 Glutamate-aspartate symporter signature 305 331 9.1E-31 T 12-10-2018 MIM_c08750 29a3a60ddbf3f6a9e1a01086363447ff 447 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 308 331 - T 12-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site MIM_c08750 29a3a60ddbf3f6a9e1a01086363447ff 447 Pfam PF00375 Sodium:dicarboxylate symporter family 22 414 1.7E-109 T 12-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MIM_c08750 29a3a60ddbf3f6a9e1a01086363447ff 447 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 49 64 - T 12-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site MIM_c08750 29a3a60ddbf3f6a9e1a01086363447ff 447 Gene3D G3DSA:1.10.3860.10 12 430 6.3E-124 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MIM_c08750 29a3a60ddbf3f6a9e1a01086363447ff 447 Hamap MF_01300 C4-dicarboxylate transport protein [dctA]. 15 441 37.761 T 12-10-2018 IPR023954 C4-dicarboxylate transport protein GO:0006835|GO:0015293|GO:0016021 MIM_c27090 f4d000fa2952b83b1db4243b65d8da73 340 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 187 282 5.2E-24 T 12-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 MIM_c27090 f4d000fa2952b83b1db4243b65d8da73 340 Gene3D G3DSA:2.60.120.330 4 331 5.9E-93 T 12-10-2018 IPR027443 Isopenicillin N synthase-like MIM_c27090 f4d000fa2952b83b1db4243b65d8da73 340 SUPERFAMILY SSF51197 9 329 8.93E-89 T 12-10-2018 MIM_c27090 f4d000fa2952b83b1db4243b65d8da73 340 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 11 135 8.5E-33 T 12-10-2018 IPR026992 Non-haem dioxygenase N-terminal domain MIM_c27090 f4d000fa2952b83b1db4243b65d8da73 340 PRINTS PR00682 Isopenicillin N synthase signature 207 228 9.2E-14 T 12-10-2018 MIM_c27090 f4d000fa2952b83b1db4243b65d8da73 340 PRINTS PR00682 Isopenicillin N synthase signature 35 52 9.2E-14 T 12-10-2018 MIM_c27090 f4d000fa2952b83b1db4243b65d8da73 340 PRINTS PR00682 Isopenicillin N synthase signature 242 268 9.2E-14 T 12-10-2018 MIM_c16170 9677a843eb921a91ccab866c8b2cedfb 223 SMART SM00986 50 211 2.4E-41 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MIM_c16170 9677a843eb921a91ccab866c8b2cedfb 223 SMART SM00987 50 211 2.4E-41 T 12-10-2018 MIM_c16170 9677a843eb921a91ccab866c8b2cedfb 223 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 58 67 - T 12-10-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MIM_c16170 9677a843eb921a91ccab866c8b2cedfb 223 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 6 215 3.7E-89 T 12-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MIM_c16170 9677a843eb921a91ccab866c8b2cedfb 223 Pfam PF03167 Uracil DNA glycosylase superfamily 55 210 5.1E-27 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MIM_c16170 9677a843eb921a91ccab866c8b2cedfb 223 Gene3D G3DSA:3.40.470.10 3 223 7.2E-105 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MIM_c16170 9677a843eb921a91ccab866c8b2cedfb 223 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 5 222 40.753 T 12-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MIM_c16170 9677a843eb921a91ccab866c8b2cedfb 223 SUPERFAMILY SSF52141 5 222 1.5E-95 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MIM_c06510 d99e063b470f1db31f120ceb9b46a48b 447 TIGRFAM TIGR03353 VI_chp_4: type VI secretion protein, VC_A0114 family 5 443 1.5E-139 T 12-10-2018 IPR010263 Type VI secretion protein, VC_A0114 MIM_c06510 d99e063b470f1db31f120ceb9b46a48b 447 Pfam PF05936 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE 19 441 9.0E-149 T 12-10-2018 IPR010263 Type VI secretion protein, VC_A0114 MIM_c20350 760110842ced49af898a0199ec5fde33 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 323 4.1E-70 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c20350 760110842ced49af898a0199ec5fde33 327 Gene3D G3DSA:3.40.190.10 129 252 3.0E-92 T 12-10-2018 MIM_c20350 760110842ced49af898a0199ec5fde33 327 SUPERFAMILY SSF53850 99 290 1.18E-7 T 12-10-2018 MIM_c20350 760110842ced49af898a0199ec5fde33 327 Gene3D G3DSA:3.40.190.150 32 317 3.0E-92 T 12-10-2018 MIM_c20350 760110842ced49af898a0199ec5fde33 327 PIRSF PIRSF017082 2 327 3.6E-63 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c35350 b32ccdac4a73308a6a685f9d7e13946f 441 Pfam PF00296 Luciferase-like monooxygenase 19 389 1.1E-64 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MIM_c35350 b32ccdac4a73308a6a685f9d7e13946f 441 PIRSF PIRSF000337 4 440 6.2E-166 T 12-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MIM_c35350 b32ccdac4a73308a6a685f9d7e13946f 441 SUPERFAMILY SSF51679 6 437 2.62E-139 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MIM_c35350 b32ccdac4a73308a6a685f9d7e13946f 441 Gene3D G3DSA:3.20.20.30 3 440 4.8E-164 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MIM_c35350 b32ccdac4a73308a6a685f9d7e13946f 441 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 10 431 3.3E-183 T 12-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MIM_c29220 da650fc98d51ed2c1e3da24ce681c489 414 PIRSF PIRSF000412 2 414 4.7E-163 T 12-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MIM_c29220 da650fc98d51ed2c1e3da24ce681c489 414 SUPERFAMILY SSF53383 7 413 3.58E-179 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c29220 da650fc98d51ed2c1e3da24ce681c489 414 Gene3D G3DSA:3.40.640.10 37 286 2.8E-183 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c29220 da650fc98d51ed2c1e3da24ce681c489 414 Gene3D G3DSA:3.90.1150.10 10 392 2.8E-183 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c29220 da650fc98d51ed2c1e3da24ce681c489 414 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 221 237 - T 12-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MIM_c29220 da650fc98d51ed2c1e3da24ce681c489 414 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 414 52.194 T 12-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MIM_c29220 da650fc98d51ed2c1e3da24ce681c489 414 Pfam PF00464 Serine hydroxymethyltransferase 8 382 3.8E-170 T 12-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MIM_c30410 20881c2ea93036e5db0dc49738845096 1000 PIRSF PIRSF037980 1 999 0.0 T 12-10-2018 IPR006277 Sarcosine oxidase, alpha subunit GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 MIM_c30410 20881c2ea93036e5db0dc49738845096 1000 SUPERFAMILY SSF51905 159 481 2.81E-34 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c30410 20881c2ea93036e5db0dc49738845096 1000 Gene3D G3DSA:2.40.30.110 904 998 1.6E-9 T 12-10-2018 MIM_c30410 20881c2ea93036e5db0dc49738845096 1000 SUPERFAMILY SSF103025 609 901 4.24E-94 T 12-10-2018 MIM_c30410 20881c2ea93036e5db0dc49738845096 1000 Pfam PF01571 Aminomethyltransferase folate-binding domain 615 879 2.2E-76 T 12-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain MIM_c30410 20881c2ea93036e5db0dc49738845096 1000 Gene3D G3DSA:3.30.70.1400 668 894 2.9E-90 T 12-10-2018 MIM_c30410 20881c2ea93036e5db0dc49738845096 1000 Gene3D G3DSA:3.50.50.60 292 418 2.4E-91 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c30410 20881c2ea93036e5db0dc49738845096 1000 Gene3D G3DSA:3.30.1360.120 610 870 2.9E-90 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 MIM_c30410 20881c2ea93036e5db0dc49738845096 1000 Gene3D G3DSA:1.10.10.1100 502 583 2.4E-91 T 12-10-2018 MIM_c30410 20881c2ea93036e5db0dc49738845096 1000 Gene3D G3DSA:3.50.50.60 170 588 2.4E-91 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c30410 20881c2ea93036e5db0dc49738845096 1000 SUPERFAMILY SSF101790 899 998 3.27E-16 T 12-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal MIM_c30410 20881c2ea93036e5db0dc49738845096 1000 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 190 3.1E-7 T 12-10-2018 MIM_c30410 20881c2ea93036e5db0dc49738845096 1000 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 280 298 3.1E-7 T 12-10-2018 MIM_c30410 20881c2ea93036e5db0dc49738845096 1000 Gene3D G3DSA:3.10.20.440 12 103 3.6E-8 T 12-10-2018 MIM_c30410 20881c2ea93036e5db0dc49738845096 1000 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 17 101 5.0E-24 T 12-10-2018 MIM_c30410 20881c2ea93036e5db0dc49738845096 1000 TIGRFAM TIGR01372 soxA: sarcosine oxidase, alpha subunit family 3 999 0.0 T 12-10-2018 IPR006277 Sarcosine oxidase, alpha subunit GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 MIM_c30410 20881c2ea93036e5db0dc49738845096 1000 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 886 985 2.3E-15 T 12-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MIM_c30410 20881c2ea93036e5db0dc49738845096 1000 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 369 385 1.3E-10 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MIM_c30410 20881c2ea93036e5db0dc49738845096 1000 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 170 192 1.3E-10 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MIM_c30410 20881c2ea93036e5db0dc49738845096 1000 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 281 289 1.3E-10 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MIM_c30410 20881c2ea93036e5db0dc49738845096 1000 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 320 344 1.3E-10 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MIM_c30410 20881c2ea93036e5db0dc49738845096 1000 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 170 428 4.7E-15 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MIM_c20550 c0f73b5df2cc67e50efab664024719ed 340 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 66 336 8.2E-58 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c20550 c0f73b5df2cc67e50efab664024719ed 340 Gene3D G3DSA:3.40.190.150 48 330 1.2E-82 T 12-10-2018 MIM_c20550 c0f73b5df2cc67e50efab664024719ed 340 SUPERFAMILY SSF53850 136 299 1.23E-8 T 12-10-2018 MIM_c20550 c0f73b5df2cc67e50efab664024719ed 340 PIRSF PIRSF017082 20 340 9.2E-56 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c20550 c0f73b5df2cc67e50efab664024719ed 340 Gene3D G3DSA:3.40.190.10 144 264 1.2E-82 T 12-10-2018 MIM_c14330 0e8e77022639902cf3992548da556f23 674 TIGRFAM TIGR00232 tktlase_bact: transketolase 14 670 1.1E-271 T 12-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 MIM_c14330 0e8e77022639902cf3992548da556f23 674 SUPERFAMILY SSF52922 542 671 5.1E-40 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MIM_c14330 0e8e77022639902cf3992548da556f23 674 Pfam PF02780 Transketolase, C-terminal domain 550 598 9.4E-9 T 12-10-2018 IPR033248 Transketolase, C-terminal domain MIM_c14330 0e8e77022639902cf3992548da556f23 674 ProSitePatterns PS00801 Transketolase signature 1. 19 39 - T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MIM_c14330 0e8e77022639902cf3992548da556f23 674 Pfam PF02779 Transketolase, pyrimidine binding domain 365 533 1.5E-46 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MIM_c14330 0e8e77022639902cf3992548da556f23 674 SMART SM00861 365 536 6.0E-68 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MIM_c14330 0e8e77022639902cf3992548da556f23 674 Gene3D G3DSA:3.40.50.970 338 547 2.7E-77 T 12-10-2018 MIM_c14330 0e8e77022639902cf3992548da556f23 674 SUPERFAMILY SSF52518 358 533 2.95E-65 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c14330 0e8e77022639902cf3992548da556f23 674 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 12 344 9.4E-154 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MIM_c14330 0e8e77022639902cf3992548da556f23 674 ProSitePatterns PS00802 Transketolase signature 2. 477 493 - T 12-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MIM_c14330 0e8e77022639902cf3992548da556f23 674 SUPERFAMILY SSF52518 11 330 5.89E-113 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c14330 0e8e77022639902cf3992548da556f23 674 Gene3D G3DSA:3.40.50.920 549 674 5.0E-38 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MIM_c14330 0e8e77022639902cf3992548da556f23 674 Gene3D G3DSA:3.40.50.970 10 336 1.0E-121 T 12-10-2018 MIM_c27740 9b30833ec5de976e9485c81a4c5a1c69 209 Pfam PF00994 Probable molybdopterin binding domain 18 160 1.1E-27 T 12-10-2018 IPR001453 MoaB/Mog domain MIM_c27740 9b30833ec5de976e9485c81a4c5a1c69 209 SMART SM00852 17 167 3.6E-22 T 12-10-2018 IPR001453 MoaB/Mog domain MIM_c27740 9b30833ec5de976e9485c81a4c5a1c69 209 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 79 92 - T 12-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 MIM_c27740 9b30833ec5de976e9485c81a4c5a1c69 209 SUPERFAMILY SSF53218 14 202 3.01E-45 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily MIM_c27740 9b30833ec5de976e9485c81a4c5a1c69 209 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 16 160 6.8E-35 T 12-10-2018 IPR001453 MoaB/Mog domain MIM_c27740 9b30833ec5de976e9485c81a4c5a1c69 209 Gene3D G3DSA:3.40.980.10 13 209 4.0E-60 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily MIM_c09010 2ac22ba65de5a4b4a6f7f0f62f023e10 484 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 483 1.1E-156 T 12-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 MIM_c09010 2ac22ba65de5a4b4a6f7f0f62f023e10 484 Gene3D G3DSA:1.10.10.410 423 484 1.1E-22 T 12-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal MIM_c09010 2ac22ba65de5a4b4a6f7f0f62f023e10 484 Pfam PF02934 GatB/GatE catalytic domain 5 293 1.5E-107 T 12-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 MIM_c09010 2ac22ba65de5a4b4a6f7f0f62f023e10 484 SUPERFAMILY SSF55931 4 300 4.32E-117 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 MIM_c09010 2ac22ba65de5a4b4a6f7f0f62f023e10 484 Pfam PF02637 GatB domain 332 483 2.5E-48 T 12-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 MIM_c09010 2ac22ba65de5a4b4a6f7f0f62f023e10 484 Gene3D G3DSA:1.10.150.380 305 421 6.6E-29 T 12-10-2018 MIM_c09010 2ac22ba65de5a4b4a6f7f0f62f023e10 484 SMART SM00845 332 483 1.6E-75 T 12-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 MIM_c09010 2ac22ba65de5a4b4a6f7f0f62f023e10 484 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 148 162 - T 12-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 MIM_c09010 2ac22ba65de5a4b4a6f7f0f62f023e10 484 SUPERFAMILY SSF89095 301 407 8.24E-30 T 12-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 MIM_c09010 2ac22ba65de5a4b4a6f7f0f62f023e10 484 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 484 36.794 T 12-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 MIM_c28520 10241e66e5b64ecf039c0859fc940651 358 Gene3D G3DSA:1.10.10.10 4 121 6.7E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c28520 10241e66e5b64ecf039c0859fc940651 358 Gene3D G3DSA:3.40.190.10 205 307 9.0E-10 T 12-10-2018 MIM_c28520 10241e66e5b64ecf039c0859fc940651 358 Pfam PF12727 PBP superfamily domain 152 326 3.8E-46 T 12-10-2018 IPR024370 PBP domain MIM_c28520 10241e66e5b64ecf039c0859fc940651 358 Gene3D G3DSA:3.40.190.10 199 330 9.0E-10 T 12-10-2018 MIM_c28520 10241e66e5b64ecf039c0859fc940651 358 SUPERFAMILY SSF53850 197 341 2.32E-14 T 12-10-2018 MIM_c28520 10241e66e5b64ecf039c0859fc940651 358 SUPERFAMILY SSF46785 9 141 6.98E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c28520 10241e66e5b64ecf039c0859fc940651 358 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 28 84 4.1E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c32500 c9a4d2c0582e0faccd32a95a9f090cd0 462 Gene3D G3DSA:3.40.120.10 1 150 5.9E-45 T 12-10-2018 MIM_c32500 c9a4d2c0582e0faccd32a95a9f090cd0 462 SUPERFAMILY SSF53738 155 256 2.12E-31 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MIM_c32500 c9a4d2c0582e0faccd32a95a9f090cd0 462 SUPERFAMILY SSF53738 6 133 1.14E-36 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MIM_c32500 c9a4d2c0582e0faccd32a95a9f090cd0 462 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 157 254 8.0E-26 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MIM_c32500 c9a4d2c0582e0faccd32a95a9f090cd0 462 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 392 448 2.1E-10 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MIM_c32500 c9a4d2c0582e0faccd32a95a9f090cd0 462 Gene3D G3DSA:3.30.310.50 369 462 7.1E-27 T 12-10-2018 MIM_c32500 c9a4d2c0582e0faccd32a95a9f090cd0 462 SUPERFAMILY SSF55957 369 460 9.94E-20 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MIM_c32500 c9a4d2c0582e0faccd32a95a9f090cd0 462 Gene3D G3DSA:3.40.120.10 173 250 2.1E-32 T 12-10-2018 MIM_c32500 c9a4d2c0582e0faccd32a95a9f090cd0 462 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 259 357 3.5E-20 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MIM_c32500 c9a4d2c0582e0faccd32a95a9f090cd0 462 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 98 107 - T 12-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MIM_c32500 c9a4d2c0582e0faccd32a95a9f090cd0 462 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 97 111 7.5E-22 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MIM_c32500 c9a4d2c0582e0faccd32a95a9f090cd0 462 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 205 218 7.5E-22 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MIM_c32500 c9a4d2c0582e0faccd32a95a9f090cd0 462 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 234 249 7.5E-22 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MIM_c32500 c9a4d2c0582e0faccd32a95a9f090cd0 462 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 171 190 7.5E-22 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MIM_c32500 c9a4d2c0582e0faccd32a95a9f090cd0 462 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 9 128 5.8E-31 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MIM_c32500 c9a4d2c0582e0faccd32a95a9f090cd0 462 Gene3D G3DSA:3.40.120.10 251 368 1.2E-40 T 12-10-2018 MIM_c32500 c9a4d2c0582e0faccd32a95a9f090cd0 462 SUPERFAMILY SSF53738 258 356 1.61E-30 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MIM_c23630 e7f7eb021e9350396f7fe03902f99ef8 114 PIRSF PIRSF020408 5 109 1.6E-38 T 12-10-2018 IPR016772 Uncharacterised conserved protein UCP020408 MIM_c23630 e7f7eb021e9350396f7fe03902f99ef8 114 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 7 96 1.5E-16 T 12-10-2018 IPR016772 Uncharacterised conserved protein UCP020408 MIM_c28140 058aadecc693d9f76de58dda0bb3291f 304 SUPERFAMILY SSF53850 88 297 1.63E-43 T 12-10-2018 MIM_c28140 058aadecc693d9f76de58dda0bb3291f 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 7.0E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c28140 058aadecc693d9f76de58dda0bb3291f 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 7.0E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c28140 058aadecc693d9f76de58dda0bb3291f 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 7.0E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c28140 058aadecc693d9f76de58dda0bb3291f 304 Gene3D G3DSA:1.10.10.10 3 89 3.0E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c28140 058aadecc693d9f76de58dda0bb3291f 304 Pfam PF03466 LysR substrate binding domain 88 292 4.0E-39 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c28140 058aadecc693d9f76de58dda0bb3291f 304 SUPERFAMILY SSF46785 4 87 1.43E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c28140 058aadecc693d9f76de58dda0bb3291f 304 Gene3D G3DSA:3.40.190.290 91 293 1.7E-64 T 12-10-2018 MIM_c28140 058aadecc693d9f76de58dda0bb3291f 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.0E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c40160 05fb947be1e85f32ad1f710f9673d60e 386 SUPERFAMILY SSF47203 229 384 9.99E-43 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c40160 05fb947be1e85f32ad1f710f9673d60e 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 218 2.8E-21 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MIM_c40160 05fb947be1e85f32ad1f710f9673d60e 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 363 4.5E-33 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MIM_c40160 05fb947be1e85f32ad1f710f9673d60e 386 Gene3D G3DSA:1.20.140.10 236 379 3.8E-36 T 12-10-2018 MIM_c40160 05fb947be1e85f32ad1f710f9673d60e 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 115 1.1E-24 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c40160 05fb947be1e85f32ad1f710f9673d60e 386 PIRSF PIRSF016578 236 385 8.4E-7 T 12-10-2018 MIM_c40160 05fb947be1e85f32ad1f710f9673d60e 386 PIRSF PIRSF016578 1 193 2.4E-9 T 12-10-2018 MIM_c40160 05fb947be1e85f32ad1f710f9673d60e 386 Gene3D G3DSA:1.10.540.10 3 115 1.0E-28 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c40160 05fb947be1e85f32ad1f710f9673d60e 386 SUPERFAMILY SSF56645 5 243 3.14E-60 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c40160 05fb947be1e85f32ad1f710f9673d60e 386 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 338 357 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MIM_c40160 05fb947be1e85f32ad1f710f9673d60e 386 Gene3D G3DSA:2.40.110.10 119 235 1.6E-32 T 12-10-2018 MIM_c40030 042830e8ada2dcbad401a5a9ecb9852f 336 SMART SM00930 259 334 4.0E-20 T 12-10-2018 IPR018449 NIL domain MIM_c40030 042830e8ada2dcbad401a5a9ecb9852f 336 Gene3D G3DSA:3.40.50.300 1 249 3.7E-79 T 12-10-2018 MIM_c40030 042830e8ada2dcbad401a5a9ecb9852f 336 Gene3D G3DSA:3.30.70.260 250 336 7.4E-16 T 12-10-2018 MIM_c40030 042830e8ada2dcbad401a5a9ecb9852f 336 SUPERFAMILY SSF55021 259 334 1.37E-16 T 12-10-2018 MIM_c40030 042830e8ada2dcbad401a5a9ecb9852f 336 Pfam PF09383 NIL domain 261 333 2.1E-21 T 12-10-2018 IPR018449 NIL domain MIM_c40030 042830e8ada2dcbad401a5a9ecb9852f 336 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c40030 042830e8ada2dcbad401a5a9ecb9852f 336 SMART SM00382 30 217 5.4E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c40030 042830e8ada2dcbad401a5a9ecb9852f 336 SUPERFAMILY SSF52540 1 238 4.56E-86 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c40030 042830e8ada2dcbad401a5a9ecb9852f 336 Pfam PF00005 ABC transporter 22 169 3.2E-37 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c25000 4a1a437307fa9b1c0d89371cfd3a9c37 392 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 MIM_c25000 4a1a437307fa9b1c0d89371cfd3a9c37 392 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 12-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 MIM_c25000 4a1a437307fa9b1c0d89371cfd3a9c37 392 PIRSF PIRSF000429 1 392 2.0E-112 T 12-10-2018 IPR002155 Thiolase GO:0016747 MIM_c25000 4a1a437307fa9b1c0d89371cfd3a9c37 392 SUPERFAMILY SSF53901 1 266 7.77E-66 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c25000 4a1a437307fa9b1c0d89371cfd3a9c37 392 Gene3D G3DSA:3.40.47.10 4 275 7.8E-134 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c25000 4a1a437307fa9b1c0d89371cfd3a9c37 392 Pfam PF02803 Thiolase, C-terminal domain 270 390 4.6E-42 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 MIM_c25000 4a1a437307fa9b1c0d89371cfd3a9c37 392 Pfam PF00108 Thiolase, N-terminal domain 5 261 2.0E-57 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 MIM_c25000 4a1a437307fa9b1c0d89371cfd3a9c37 392 SUPERFAMILY SSF53901 271 391 5.76E-40 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c25000 4a1a437307fa9b1c0d89371cfd3a9c37 392 Gene3D G3DSA:3.40.47.10 126 384 7.8E-134 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c25000 4a1a437307fa9b1c0d89371cfd3a9c37 392 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 3.7E-121 T 12-10-2018 IPR002155 Thiolase GO:0016747 MIM_c40400 a2f98b7694dcde2eeea8a5348e187a0a 247 Gene3D G3DSA:3.90.550.10 3 231 1.0E-23 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MIM_c40400 a2f98b7694dcde2eeea8a5348e187a0a 247 SUPERFAMILY SSF53448 1 225 1.31E-26 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MIM_c40400 a2f98b7694dcde2eeea8a5348e187a0a 247 Pfam PF00535 Glycosyl transferase family 2 7 133 2.8E-16 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MIM_c03680 2034c805470c115e57941d0ce8c9b475 123 Pfam PF09722 Protein of unknown function (DUF2384) 70 121 6.9E-10 T 12-10-2018 IPR024467 Domain of unknown function DUF2384 MIM_c03680 2034c805470c115e57941d0ce8c9b475 123 SUPERFAMILY SSF47413 10 50 4.34E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c03680 2034c805470c115e57941d0ce8c9b475 123 Pfam PF01381 Helix-turn-helix 23 47 4.2E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c24110 86b5066db910d227eaadf06f9f395518 776 SUPERFAMILY SSF81301 217 395 1.63E-55 T 12-10-2018 MIM_c24110 86b5066db910d227eaadf06f9f395518 776 Pfam PF13291 ACT domain 700 775 5.9E-18 T 12-10-2018 IPR002912 ACT domain MIM_c24110 86b5066db910d227eaadf06f9f395518 776 Gene3D G3DSA:3.30.460.10 218 350 2.7E-44 T 12-10-2018 MIM_c24110 86b5066db910d227eaadf06f9f395518 776 SUPERFAMILY SSF109604 16 215 3.14E-37 T 12-10-2018 MIM_c24110 86b5066db910d227eaadf06f9f395518 776 Pfam PF13328 HD domain 37 201 7.2E-40 T 12-10-2018 IPR003607 HD/PDEase domain MIM_c24110 86b5066db910d227eaadf06f9f395518 776 Gene3D G3DSA:3.30.70.260 699 776 1.7E-17 T 12-10-2018 MIM_c24110 86b5066db910d227eaadf06f9f395518 776 SMART SM00954 260 370 5.0E-59 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 MIM_c24110 86b5066db910d227eaadf06f9f395518 776 SUPERFAMILY SSF81271 447 507 3.05E-18 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MIM_c24110 86b5066db910d227eaadf06f9f395518 776 Pfam PF02824 TGS domain 449 507 1.9E-21 T 12-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 MIM_c24110 86b5066db910d227eaadf06f9f395518 776 SUPERFAMILY SSF55021 699 775 1.46E-11 T 12-10-2018 MIM_c24110 86b5066db910d227eaadf06f9f395518 776 Pfam PF04607 Region found in RelA / SpoT proteins 260 369 4.6E-36 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 MIM_c24110 86b5066db910d227eaadf06f9f395518 776 Gene3D G3DSA:3.10.20.30 445 513 2.0E-27 T 12-10-2018 IPR012675 Beta-grasp domain superfamily MIM_c24110 86b5066db910d227eaadf06f9f395518 776 Gene3D G3DSA:1.10.3210.10 12 216 2.7E-36 T 12-10-2018 MIM_c15600 a1a6fb1591c37a1d5d386d12454e8f08 244 Pfam PF00588 SpoU rRNA Methylase family 98 237 5.1E-39 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MIM_c15600 a1a6fb1591c37a1d5d386d12454e8f08 244 SUPERFAMILY SSF75217 70 243 6.54E-48 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases MIM_c15600 a1a6fb1591c37a1d5d386d12454e8f08 244 SMART SM00967 6 82 3.2E-17 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MIM_c15600 a1a6fb1591c37a1d5d386d12454e8f08 244 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 7 80 7.0E-17 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MIM_c15600 a1a6fb1591c37a1d5d386d12454e8f08 244 Hamap MF_01887 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB [rlmB]. 4 244 42.821 T 12-10-2018 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB MIM_c15600 a1a6fb1591c37a1d5d386d12454e8f08 244 Gene3D G3DSA:3.40.1280.10 80 244 7.4E-56 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MIM_c15600 a1a6fb1591c37a1d5d386d12454e8f08 244 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 5 243 4.2E-72 T 12-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 MIM_c15600 a1a6fb1591c37a1d5d386d12454e8f08 244 SUPERFAMILY SSF55315 2 78 6.71E-17 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like MIM_c15600 a1a6fb1591c37a1d5d386d12454e8f08 244 Gene3D G3DSA:3.30.1330.30 1 78 1.7E-21 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like MIM_c27820 7c4a266b00b808dda8675867c55da1f4 153 SUPERFAMILY SSF55811 17 142 1.62E-17 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MIM_c27820 7c4a266b00b808dda8675867c55da1f4 153 Pfam PF00293 NUDIX domain 23 131 2.9E-12 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MIM_c27820 7c4a266b00b808dda8675867c55da1f4 153 Gene3D G3DSA:3.90.79.10 1 151 7.1E-26 T 12-10-2018 MIM_c27820 7c4a266b00b808dda8675867c55da1f4 153 PRINTS PR00502 NUDIX hydrolase family signature 59 74 4.9E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MIM_c27820 7c4a266b00b808dda8675867c55da1f4 153 PRINTS PR00502 NUDIX hydrolase family signature 45 59 4.9E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MIM_c26390 27fe6f1523959e452fb1d077f4c1bcce 326 SMART SM00382 32 231 8.8E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c26390 27fe6f1523959e452fb1d077f4c1bcce 326 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c26390 27fe6f1523959e452fb1d077f4c1bcce 326 Pfam PF00005 ABC transporter 24 181 6.4E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c26390 27fe6f1523959e452fb1d077f4c1bcce 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 315 4.2E-23 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c26390 27fe6f1523959e452fb1d077f4c1bcce 326 SUPERFAMILY SSF52540 3 253 9.03E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c26390 27fe6f1523959e452fb1d077f4c1bcce 326 Gene3D G3DSA:3.40.50.300 1 319 1.5E-94 T 12-10-2018 MIM_c26390 27fe6f1523959e452fb1d077f4c1bcce 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 297 2.3E-16 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c37430 97343754f0505b11cb982f7dfc4030c2 386 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 197 211 - T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MIM_c37430 97343754f0505b11cb982f7dfc4030c2 386 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 18 384 2.9E-113 T 12-10-2018 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8 MIM_c37430 97343754f0505b11cb982f7dfc4030c2 386 Gene3D G3DSA:3.40.640.10 4 253 2.7E-64 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c37430 97343754f0505b11cb982f7dfc4030c2 386 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 17 382 1.3E-92 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MIM_c37430 97343754f0505b11cb982f7dfc4030c2 386 PIRSF PIRSF001434 1 386 5.0E-109 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MIM_c37430 97343754f0505b11cb982f7dfc4030c2 386 SUPERFAMILY SSF53383 29 382 6.53E-80 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c37430 97343754f0505b11cb982f7dfc4030c2 386 Gene3D G3DSA:3.90.1150.10 254 386 9.1E-37 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c30940 0cdded0ce0c3aefa9a4968033b23731d 237 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 12 191 1.4E-71 T 12-10-2018 IPR022301 Integral membrane protein YjbE MIM_c30940 0cdded0ce0c3aefa9a4968033b23731d 237 Pfam PF03741 Integral membrane protein TerC family 14 190 3.0E-44 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 SUPERFAMILY SSF56059 128 408 6.01E-106 T 12-10-2018 MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1065 13.239 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 304 311 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 Gene3D G3DSA:3.40.50.1380 938 1078 5.8E-37 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 SUPERFAMILY SSF52335 937 1075 2.88E-37 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 Pfam PF02142 MGS-like domain 958 1039 9.0E-19 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 429 549 3.9E-44 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 SUPERFAMILY SSF52440 1 127 3.88E-49 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 840 847 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 SMART SM00851 957 1044 5.6E-28 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 SUPERFAMILY SSF56059 675 935 1.54E-104 T 12-10-2018 MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 SUPERFAMILY SSF52440 558 677 2.59E-49 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1073 13.406 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 Gene3D G3DSA:3.40.50.20 1 116 1.4E-49 T 12-10-2018 MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 SUPERFAMILY SSF48108 403 556 1.57E-55 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 Gene3D G3DSA:3.30.470.20 667 937 1.2E-120 T 12-10-2018 MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 304 333 3.8E-66 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 175 187 3.8E-66 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 3.8E-66 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 211 230 3.8E-66 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 387 405 3.8E-66 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 246 263 3.8E-66 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 3.8E-66 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 Gene3D G3DSA:1.10.1030.10 410 555 1.1E-51 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 SMART SM01096 426 549 4.0E-79 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 711 725 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 Gene3D G3DSA:3.30.470.20 120 409 3.5E-127 T 12-10-2018 MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 Gene3D G3DSA:3.40.50.20 556 664 2.1E-49 T 12-10-2018 MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1054 0.0 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 341 3.5E-69 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MIM_c26080 53ec132d1aa0c88cee0988170e09538b 1083 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 675 877 2.5E-37 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MIM_c00740 40157bd8a008e61376e97a52bebc138c 333 TIGRFAM TIGR02551 SpaO_YscQ: type III secretion apparatus protein, YscQ/HrcQ family 149 328 8.2E-34 T 12-10-2018 IPR013385 Type III secretion system apparatus protein YscQ/HrcQ/SpaO GO:0030254 MIM_c00740 40157bd8a008e61376e97a52bebc138c 333 SUPERFAMILY SSF101801 257 331 4.05E-17 T 12-10-2018 IPR036429 SpoA-like superfamily MIM_c00740 40157bd8a008e61376e97a52bebc138c 333 Gene3D G3DSA:2.30.330.10 246 332 1.2E-24 T 12-10-2018 IPR036429 SpoA-like superfamily MIM_c00740 40157bd8a008e61376e97a52bebc138c 333 PRINTS PR00956 Flagellar motor switch protein FliN signature 259 275 4.0E-12 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MIM_c00740 40157bd8a008e61376e97a52bebc138c 333 PRINTS PR00956 Flagellar motor switch protein FliN signature 292 305 4.0E-12 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MIM_c00740 40157bd8a008e61376e97a52bebc138c 333 PRINTS PR00956 Flagellar motor switch protein FliN signature 276 292 4.0E-12 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MIM_c00740 40157bd8a008e61376e97a52bebc138c 333 PRINTS PR00956 Flagellar motor switch protein FliN signature 305 320 4.0E-12 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MIM_c00740 40157bd8a008e61376e97a52bebc138c 333 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 260 328 1.5E-16 T 12-10-2018 IPR001543 Surface presentation of antigen (SpoA) MIM_c32420 57d8108a01041a1e664e5daaecfe8cae 214 SUPERFAMILY SSF50715 1 188 1.52E-52 T 12-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MIM_c32420 57d8108a01041a1e664e5daaecfe8cae 214 Gene3D G3DSA:2.170.120.20 95 194 5.8E-23 T 12-10-2018 IPR037121 Ribosomal protein L25, C-terminal MIM_c32420 57d8108a01041a1e664e5daaecfe8cae 214 Hamap MF_01336 50S ribosomal protein L25 [rplY]. 1 93 23.465 T 12-10-2018 IPR020055 Ribosomal protein L25, short-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 MIM_c32420 57d8108a01041a1e664e5daaecfe8cae 214 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 4 171 5.4E-43 T 12-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 MIM_c32420 57d8108a01041a1e664e5daaecfe8cae 214 Pfam PF01386 Ribosomal L25p family 4 90 2.8E-24 T 12-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 MIM_c32420 57d8108a01041a1e664e5daaecfe8cae 214 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 99 179 3.8E-24 T 12-10-2018 IPR020057 Ribosomal protein L25, beta domain MIM_c32420 57d8108a01041a1e664e5daaecfe8cae 214 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 1 93 3.0E-28 T 12-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 MIM_c32420 57d8108a01041a1e664e5daaecfe8cae 214 Gene3D G3DSA:2.40.240.10 1 93 5.4E-31 T 12-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MIM_c32420 57d8108a01041a1e664e5daaecfe8cae 214 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 1 184 29.229 T 12-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 MIM_c19440 3828031963f93e2efdb6a45d265161c8 152 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 3 146 6.8E-58 T 12-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MIM_c19440 3828031963f93e2efdb6a45d265161c8 152 SUPERFAMILY SSF54637 5 147 9.31E-48 T 12-10-2018 IPR029069 HotDog domain superfamily MIM_c19440 3828031963f93e2efdb6a45d265161c8 152 Pfam PF07977 FabA-like domain 12 140 1.3E-39 T 12-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MIM_c19440 3828031963f93e2efdb6a45d265161c8 152 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 3 148 34.238 T 12-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MIM_c19440 3828031963f93e2efdb6a45d265161c8 152 Gene3D G3DSA:3.10.129.10 1 149 4.6E-58 T 12-10-2018 MIM_c23240 ebe346d46d97d3022853f2448f920995 908 Pfam PF01433 Peptidase family M1 domain 211 444 9.5E-52 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MIM_c23240 ebe346d46d97d3022853f2448f920995 908 Gene3D G3DSA:1.25.50.10 582 907 8.9E-111 T 12-10-2018 IPR037144 Peptidase M1, alanyl aminopeptidase, C-terminal domain superfamily MIM_c23240 ebe346d46d97d3022853f2448f920995 908 Pfam PF11940 Domain of unknown function (DUF3458) Ig-like fold 463 581 6.6E-26 T 12-10-2018 IPR035414 Peptidase M1, alanyl aminopeptidase, Ig-like fold MIM_c23240 ebe346d46d97d3022853f2448f920995 908 SUPERFAMILY SSF63737 5 196 5.75E-42 T 12-10-2018 MIM_c23240 ebe346d46d97d3022853f2448f920995 908 Gene3D G3DSA:1.10.1740.60 198 282 1.2E-34 T 12-10-2018 MIM_c23240 ebe346d46d97d3022853f2448f920995 908 Gene3D G3DSA:2.60.40.1840 463 581 3.0E-29 T 12-10-2018 IPR038438 Alanyl aminopeptidase, Ig-like domain superfamily MIM_c23240 ebe346d46d97d3022853f2448f920995 908 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 261 271 2.0E-7 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MIM_c23240 ebe346d46d97d3022853f2448f920995 908 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 316 328 2.0E-7 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MIM_c23240 ebe346d46d97d3022853f2448f920995 908 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 179 194 2.0E-7 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MIM_c23240 ebe346d46d97d3022853f2448f920995 908 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 297 312 2.0E-7 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MIM_c23240 ebe346d46d97d3022853f2448f920995 908 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 13 906 0.0 T 12-10-2018 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 MIM_c23240 ebe346d46d97d3022853f2448f920995 908 SUPERFAMILY SSF55486 207 469 5.49E-69 T 12-10-2018 MIM_c23240 ebe346d46d97d3022853f2448f920995 908 Gene3D G3DSA:1.10.390.10 283 462 6.2E-60 T 12-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily MIM_c23240 ebe346d46d97d3022853f2448f920995 908 Gene3D G3DSA:2.60.40.1730 16 197 1.8E-68 T 12-10-2018 MIM_c23240 ebe346d46d97d3022853f2448f920995 908 Pfam PF17432 Domain of unknown function (DUF3458_C) ARM repeats 585 906 4.9E-116 T 12-10-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal MIM_c03530 2e9a57e49b5919ca903511946a829388 560 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 8 93 1.4E-22 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MIM_c03530 2e9a57e49b5919ca903511946a829388 560 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 131 140 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c03530 2e9a57e49b5919ca903511946a829388 560 Pfam PF00750 tRNA synthetases class I (R) 103 409 3.4E-21 T 12-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 MIM_c03530 2e9a57e49b5919ca903511946a829388 560 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 9 560 1.2E-131 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MIM_c03530 2e9a57e49b5919ca903511946a829388 560 PRINTS PR01038 Arginyl-tRNA synthetase signature 310 331 3.1E-23 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MIM_c03530 2e9a57e49b5919ca903511946a829388 560 PRINTS PR01038 Arginyl-tRNA synthetase signature 121 136 3.1E-23 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MIM_c03530 2e9a57e49b5919ca903511946a829388 560 PRINTS PR01038 Arginyl-tRNA synthetase signature 136 152 3.1E-23 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MIM_c03530 2e9a57e49b5919ca903511946a829388 560 PRINTS PR01038 Arginyl-tRNA synthetase signature 160 173 3.1E-23 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MIM_c03530 2e9a57e49b5919ca903511946a829388 560 SMART SM00836 443 560 1.3E-48 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MIM_c03530 2e9a57e49b5919ca903511946a829388 560 Gene3D G3DSA:1.10.730.10 438 560 2.7E-151 T 12-10-2018 MIM_c03530 2e9a57e49b5919ca903511946a829388 560 SUPERFAMILY SSF52374 118 454 1.07E-81 T 12-10-2018 MIM_c03530 2e9a57e49b5919ca903511946a829388 560 Hamap MF_00123 Arginine--tRNA ligase [argS]. 3 560 25.259 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MIM_c03530 2e9a57e49b5919ca903511946a829388 560 Gene3D G3DSA:3.40.50.620 121 437 2.7E-151 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c03530 2e9a57e49b5919ca903511946a829388 560 SUPERFAMILY SSF55190 5 113 4.45E-22 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 MIM_c03530 2e9a57e49b5919ca903511946a829388 560 Gene3D G3DSA:3.30.1360.70 2 112 3.0E-24 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 MIM_c03530 2e9a57e49b5919ca903511946a829388 560 SMART SM01016 7 93 4.4E-33 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MIM_c03530 2e9a57e49b5919ca903511946a829388 560 Pfam PF05746 DALR anticodon binding domain 443 560 1.1E-33 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MIM_c03530 2e9a57e49b5919ca903511946a829388 560 SUPERFAMILY SSF47323 438 560 1.96E-33 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c16510 220e6c2397a0a5b84a8180ce1132f44d 249 SUPERFAMILY SSF52402 1 242 4.74E-85 T 12-10-2018 MIM_c16510 220e6c2397a0a5b84a8180ce1132f44d 249 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 12-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 MIM_c16510 220e6c2397a0a5b84a8180ce1132f44d 249 SMART SM00893 23 211 6.8E-67 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MIM_c16510 220e6c2397a0a5b84a8180ce1132f44d 249 Pfam PF01012 Electron transfer flavoprotein domain 29 206 6.2E-44 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MIM_c16510 220e6c2397a0a5b84a8180ce1132f44d 249 Gene3D G3DSA:3.40.50.620 1 247 2.2E-87 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c16510 220e6c2397a0a5b84a8180ce1132f44d 249 PIRSF PIRSF000090 1 249 1.2E-85 T 12-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 MIM_c32120 4fb10f90f40c02c979172a25cede5a07 185 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 10 151 25.862 T 12-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MIM_c32120 4fb10f90f40c02c979172a25cede5a07 185 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 16 146 1.4E-37 T 12-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MIM_c32120 4fb10f90f40c02c979172a25cede5a07 185 SUPERFAMILY SSF52121 8 151 2.09E-48 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MIM_c32120 4fb10f90f40c02c979172a25cede5a07 185 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 14 148 8.4E-48 T 12-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MIM_c32120 4fb10f90f40c02c979172a25cede5a07 185 Gene3D G3DSA:3.40.50.960 5 151 5.1E-50 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MIM_c15270 27ab395391061e4cdd379557929d40f0 487 SUPERFAMILY SSF50249 39 124 9.53E-18 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c15270 27ab395391061e4cdd379557929d40f0 487 SMART SM00316 37 118 1.1E-10 T 12-10-2018 IPR022967 RNA-binding domain, S1 MIM_c15270 27ab395391061e4cdd379557929d40f0 487 Gene3D G3DSA:2.40.50.140 31 124 1.1E-27 T 12-10-2018 MIM_c15270 27ab395391061e4cdd379557929d40f0 487 Pfam PF00575 S1 RNA binding domain 37 105 7.3E-5 T 12-10-2018 IPR003029 S1 domain GO:0003676 MIM_c15270 27ab395391061e4cdd379557929d40f0 487 Pfam PF10150 Ribonuclease E/G family 120 391 5.2E-100 T 12-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 MIM_c15270 27ab395391061e4cdd379557929d40f0 487 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 424 1.1E-149 T 12-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 MIM_c29350 e8f639eb6aaf5f501be80393168e4eed 822 Pfam PF00583 Acetyltransferase (GNAT) family 726 798 3.3E-8 T 12-10-2018 IPR000182 GNAT domain MIM_c29350 e8f639eb6aaf5f501be80393168e4eed 822 Pfam PF13549 ATP-grasp domain 506 615 1.2E-18 T 12-10-2018 MIM_c29350 e8f639eb6aaf5f501be80393168e4eed 822 SUPERFAMILY SSF55729 656 805 1.46E-18 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c29350 e8f639eb6aaf5f501be80393168e4eed 822 Gene3D G3DSA:3.30.470.20 506 602 1.6E-15 T 12-10-2018 MIM_c29350 e8f639eb6aaf5f501be80393168e4eed 822 SUPERFAMILY SSF52210 278 436 2.49E-20 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c29350 e8f639eb6aaf5f501be80393168e4eed 822 Gene3D G3DSA:3.40.50.261 124 275 6.2E-40 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c29350 e8f639eb6aaf5f501be80393168e4eed 822 SUPERFAMILY SSF52210 125 273 4.45E-30 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c29350 e8f639eb6aaf5f501be80393168e4eed 822 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 145 271 1.8E-34 T 12-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain MIM_c29350 e8f639eb6aaf5f501be80393168e4eed 822 Gene3D G3DSA:3.40.50.261 276 441 4.6E-23 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c29350 e8f639eb6aaf5f501be80393168e4eed 822 Gene3D G3DSA:3.40.630.30 647 821 6.1E-42 T 12-10-2018 MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 SUPERFAMILY SSF82714 182 272 3.66E-21 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 SUPERFAMILY SSF82866 296 496 3.92E-49 T 12-10-2018 MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1040 0.0 T 12-10-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0006855|GO:0015562|GO:0016021 MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 Gene3D G3DSA:3.30.2090.10 722 810 0.0 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 Gene3D G3DSA:3.30.70.1320 132 332 0.0 T 12-10-2018 MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 SUPERFAMILY SSF82714 723 808 3.79E-18 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 SUPERFAMILY SSF82693 673 857 2.88E-23 T 12-10-2018 MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 Gene3D G3DSA:1.20.1640.10 8 517 0.0 T 12-10-2018 MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 Gene3D G3DSA:3.30.70.1430 572 669 0.0 T 12-10-2018 MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 SUPERFAMILY SSF82693 570 672 5.75E-29 T 12-10-2018 MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 SUPERFAMILY SSF82693 135 330 9.42E-27 T 12-10-2018 MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 Gene3D G3DSA:1.20.1640.10 518 1023 0.0 T 12-10-2018 MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 Gene3D G3DSA:3.30.70.1440 670 866 0.0 T 12-10-2018 MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 Pfam PF00873 AcrB/AcrD/AcrF family 1 1027 0.0 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 SUPERFAMILY SSF82693 38 130 4.19E-25 T 12-10-2018 MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 PRINTS PR00702 Acriflavin resistance protein family signature 624 638 6.0E-107 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 6.0E-107 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 6.0E-107 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 6.0E-107 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 6.0E-107 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 6.0E-107 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 6.0E-107 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 6.0E-107 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 PRINTS PR00702 Acriflavin resistance protein family signature 557 574 6.0E-107 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 Gene3D G3DSA:3.30.2090.10 179 275 0.0 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 SUPERFAMILY SSF82866 842 1026 1.96E-39 T 12-10-2018 MIM_c09500 0e750d515d52558b6f9efd64c560d02e 1047 Gene3D G3DSA:3.30.70.1430 38 818 0.0 T 12-10-2018 MIM_c20170 e12932a477b05fcf90395b549a698098 155 Pfam PF01575 MaoC like domain 21 122 4.9E-7 T 12-10-2018 IPR002539 MaoC-like dehydratase domain MIM_c20170 e12932a477b05fcf90395b549a698098 155 Gene3D G3DSA:3.10.129.10 1 149 3.1E-30 T 12-10-2018 MIM_c20170 e12932a477b05fcf90395b549a698098 155 SUPERFAMILY SSF54637 4 150 1.75E-23 T 12-10-2018 IPR029069 HotDog domain superfamily MIM_c24660 9aefb3e5c2e186ba75eb8eb314bb8960 250 Gene3D G3DSA:3.20.20.70 3 250 1.9E-92 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c24660 9aefb3e5c2e186ba75eb8eb314bb8960 250 Pfam PF00121 Triosephosphate isomerase 7 247 8.8E-82 T 12-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c24660 9aefb3e5c2e186ba75eb8eb314bb8960 250 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 7 241 8.2E-60 T 12-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c24660 9aefb3e5c2e186ba75eb8eb314bb8960 250 ProSitePatterns PS00171 Triosephosphate isomerase active site. 170 180 - T 12-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c24660 9aefb3e5c2e186ba75eb8eb314bb8960 250 SUPERFAMILY SSF51351 2 249 1.09E-83 T 12-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c24660 9aefb3e5c2e186ba75eb8eb314bb8960 250 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 4 250 57.262 T 12-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c18670 c95d5bbb8e09d6bd817a932786458efd 250 Gene3D G3DSA:3.40.50.720 3 247 1.3E-50 T 12-10-2018 MIM_c18670 c95d5bbb8e09d6bd817a932786458efd 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.5E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c18670 c95d5bbb8e09d6bd817a932786458efd 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.5E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c18670 c95d5bbb8e09d6bd817a932786458efd 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.5E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c18670 c95d5bbb8e09d6bd817a932786458efd 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.5E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c18670 c95d5bbb8e09d6bd817a932786458efd 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.5E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c18670 c95d5bbb8e09d6bd817a932786458efd 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.5E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c18670 c95d5bbb8e09d6bd817a932786458efd 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c18670 c95d5bbb8e09d6bd817a932786458efd 250 Pfam PF00106 short chain dehydrogenase 6 199 4.1E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c18670 c95d5bbb8e09d6bd817a932786458efd 250 SUPERFAMILY SSF51735 4 236 4.03E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c07370 cd6d8b3784cb872098ad2ea29f5bdb84 87 SUPERFAMILY SSF52833 2 86 3.21E-26 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c07370 cd6d8b3784cb872098ad2ea29f5bdb84 87 Gene3D G3DSA:3.40.30.10 1 86 8.1E-27 T 12-10-2018 MIM_c07370 cd6d8b3784cb872098ad2ea29f5bdb84 87 ProSitePatterns PS00195 Glutaredoxin active site. 7 23 - T 12-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 MIM_c07370 cd6d8b3784cb872098ad2ea29f5bdb84 87 Pfam PF00462 Glutaredoxin 5 66 1.1E-18 T 12-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 MIM_c07370 cd6d8b3784cb872098ad2ea29f5bdb84 87 PRINTS PR00160 Glutaredoxin signature 49 62 6.9E-16 T 12-10-2018 IPR014025 Glutaredoxin subgroup MIM_c07370 cd6d8b3784cb872098ad2ea29f5bdb84 87 PRINTS PR00160 Glutaredoxin signature 5 23 6.9E-16 T 12-10-2018 IPR014025 Glutaredoxin subgroup MIM_c07370 cd6d8b3784cb872098ad2ea29f5bdb84 87 PRINTS PR00160 Glutaredoxin signature 63 76 6.9E-16 T 12-10-2018 IPR014025 Glutaredoxin subgroup MIM_c07370 cd6d8b3784cb872098ad2ea29f5bdb84 87 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 5 85 7.5E-34 T 12-10-2018 IPR011900 Glutaredoxin, GrxC GO:0045454 MIM_c31190 feccde7e8e32d4bdc3ec20907577048e 746 SUPERFAMILY SSF56003 10 267 1.36E-41 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 MIM_c31190 feccde7e8e32d4bdc3ec20907577048e 746 Gene3D G3DSA:3.30.365.10 348 574 1.6E-54 T 12-10-2018 MIM_c31190 feccde7e8e32d4bdc3ec20907577048e 746 PIRSF PIRSF036389 20 746 4.1E-226 T 12-10-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related MIM_c31190 feccde7e8e32d4bdc3ec20907577048e 746 SUPERFAMILY SSF56003 348 743 3.14E-108 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 MIM_c31190 feccde7e8e32d4bdc3ec20907577048e 746 Gene3D G3DSA:3.30.365.10 66 204 2.1E-18 T 12-10-2018 MIM_c31190 feccde7e8e32d4bdc3ec20907577048e 746 Gene3D G3DSA:3.30.365.10 366 464 1.6E-54 T 12-10-2018 MIM_c31190 feccde7e8e32d4bdc3ec20907577048e 746 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 59 210 3.5E-12 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MIM_c31190 feccde7e8e32d4bdc3ec20907577048e 746 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 348 576 3.1E-30 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MIM_c31190 feccde7e8e32d4bdc3ec20907577048e 746 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 618 698 6.0E-9 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MIM_c31190 feccde7e8e32d4bdc3ec20907577048e 746 Gene3D G3DSA:3.30.365.10 603 746 2.9E-28 T 12-10-2018 MIM_c31190 feccde7e8e32d4bdc3ec20907577048e 746 Gene3D G3DSA:3.90.1170.50 205 303 1.2E-10 T 12-10-2018 MIM_c31190 feccde7e8e32d4bdc3ec20907577048e 746 SMART SM01008 233 316 4.0E-20 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MIM_c40220 2b722b4d3dea62d15dbb446453ad53ca 211 Gene3D G3DSA:1.20.1050.10 85 191 6.1E-51 T 12-10-2018 MIM_c40220 2b722b4d3dea62d15dbb446453ad53ca 211 Pfam PF00043 Glutathione S-transferase, C-terminal domain 109 192 1.4E-7 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal MIM_c40220 2b722b4d3dea62d15dbb446453ad53ca 211 Gene3D G3DSA:3.40.30.10 9 196 6.1E-51 T 12-10-2018 MIM_c40220 2b722b4d3dea62d15dbb446453ad53ca 211 SUPERFAMILY SSF52833 3 86 3.33E-23 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c40220 2b722b4d3dea62d15dbb446453ad53ca 211 SUPERFAMILY SSF47616 83 200 1.53E-22 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MIM_c40220 2b722b4d3dea62d15dbb446453ad53ca 211 Pfam PF02798 Glutathione S-transferase, N-terminal domain 6 76 2.2E-14 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MIM_c12780 b45962146165703eddee99ca02f7cbab 323 Gene3D G3DSA:3.40.190.10 125 248 2.9E-108 T 12-10-2018 MIM_c12780 b45962146165703eddee99ca02f7cbab 323 SUPERFAMILY SSF53850 114 287 2.61E-13 T 12-10-2018 MIM_c12780 b45962146165703eddee99ca02f7cbab 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 319 1.4E-80 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c12780 b45962146165703eddee99ca02f7cbab 323 PIRSF PIRSF017082 1 323 8.1E-81 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c12780 b45962146165703eddee99ca02f7cbab 323 Gene3D G3DSA:3.40.190.150 29 313 2.9E-108 T 12-10-2018 MIM_c37910 ffa72595359aa733aba2a99eb90ccc23 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 154 179 4.5E-6 T 12-10-2018 MIM_c37910 ffa72595359aa733aba2a99eb90ccc23 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 301 308 4.5E-6 T 12-10-2018 MIM_c37910 ffa72595359aa733aba2a99eb90ccc23 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 4.5E-6 T 12-10-2018 MIM_c37910 ffa72595359aa733aba2a99eb90ccc23 459 Gene3D G3DSA:3.50.50.60 122 262 7.6E-35 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c37910 ffa72595359aa733aba2a99eb90ccc23 459 PIRSF PIRSF037495 2 459 4.9E-134 T 12-10-2018 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 MIM_c37910 ffa72595359aa733aba2a99eb90ccc23 459 Pfam PF04324 BFD-like [2Fe-2S] binding domain 376 428 1.6E-5 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain MIM_c37910 ffa72595359aa733aba2a99eb90ccc23 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 9.8E-9 T 12-10-2018 MIM_c37910 ffa72595359aa733aba2a99eb90ccc23 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 286 308 9.8E-9 T 12-10-2018 MIM_c37910 ffa72595359aa733aba2a99eb90ccc23 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 110 128 9.8E-9 T 12-10-2018 MIM_c37910 ffa72595359aa733aba2a99eb90ccc23 459 SUPERFAMILY SSF51905 7 331 4.19E-35 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c37910 ffa72595359aa733aba2a99eb90ccc23 459 Gene3D G3DSA:3.50.50.60 7 310 7.6E-35 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c37910 ffa72595359aa733aba2a99eb90ccc23 459 Gene3D G3DSA:1.10.10.1100 365 437 6.1E-15 T 12-10-2018 MIM_c37910 ffa72595359aa733aba2a99eb90ccc23 459 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 308 8.8E-18 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MIM_c03330 5205a3b021ba3c1a5cae8893064ec50e 355 Gene3D G3DSA:3.60.15.10 22 293 5.0E-54 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MIM_c03330 5205a3b021ba3c1a5cae8893064ec50e 355 Pfam PF00753 Metallo-beta-lactamase superfamily 42 266 8.2E-24 T 12-10-2018 IPR001279 Metallo-beta-lactamase MIM_c03330 5205a3b021ba3c1a5cae8893064ec50e 355 SUPERFAMILY SSF56281 15 351 2.36E-68 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MIM_c03330 5205a3b021ba3c1a5cae8893064ec50e 355 SMART SM00849 42 266 5.8E-20 T 12-10-2018 IPR001279 Metallo-beta-lactamase MIM_c03330 5205a3b021ba3c1a5cae8893064ec50e 355 Gene3D G3DSA:1.10.10.10 297 350 2.5E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c14080 e0babde0965cdfd83a625e04bb4715a9 380 Gene3D G3DSA:1.10.10.10 83 176 3.9E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c14080 e0babde0965cdfd83a625e04bb4715a9 380 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 168 4.8E-48 T 12-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 MIM_c14080 e0babde0965cdfd83a625e04bb4715a9 380 Gene3D G3DSA:1.10.10.10 1 82 4.5E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c14080 e0babde0965cdfd83a625e04bb4715a9 380 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 9 171 2.7E-32 T 12-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 MIM_c14080 e0babde0965cdfd83a625e04bb4715a9 380 SUPERFAMILY SSF46785 7 82 2.72E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c14080 e0babde0965cdfd83a625e04bb4715a9 380 SUPERFAMILY SSF46785 85 160 1.54E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c20790 7bedfcc4d82af8e8a5baeef459cea03e 281 Gene3D G3DSA:3.40.50.720 4 281 3.4E-75 T 12-10-2018 MIM_c20790 7bedfcc4d82af8e8a5baeef459cea03e 281 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 188 0.0083 T 12-10-2018 MIM_c20790 7bedfcc4d82af8e8a5baeef459cea03e 281 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c20790 7bedfcc4d82af8e8a5baeef459cea03e 281 SUPERFAMILY SSF51735 6 251 1.08E-59 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c20790 7bedfcc4d82af8e8a5baeef459cea03e 281 Pfam PF00106 short chain dehydrogenase 9 190 2.4E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20790 7bedfcc4d82af8e8a5baeef459cea03e 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 3.1E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20790 7bedfcc4d82af8e8a5baeef459cea03e 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 3.1E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20790 7bedfcc4d82af8e8a5baeef459cea03e 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 3.1E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20790 7bedfcc4d82af8e8a5baeef459cea03e 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 3.1E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20790 7bedfcc4d82af8e8a5baeef459cea03e 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.1E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20790 7bedfcc4d82af8e8a5baeef459cea03e 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 8.0E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20790 7bedfcc4d82af8e8a5baeef459cea03e 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 8.0E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20790 7bedfcc4d82af8e8a5baeef459cea03e 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 8.0E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c39230 eb92009dcccb437000f70f2400f08bef 832 TIGRFAM TIGR03074 PQQ_membr_DH: membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family 13 830 0.0 T 12-10-2018 IPR017511 PQQ-dependent membrane bound dehydrogenase GO:0016021|GO:0016614|GO:0048038|GO:0055114 MIM_c39230 eb92009dcccb437000f70f2400f08bef 832 SUPERFAMILY SSF50998 174 830 2.22E-148 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MIM_c39230 eb92009dcccb437000f70f2400f08bef 832 SMART SM00564 529 560 260.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c39230 eb92009dcccb437000f70f2400f08bef 832 SMART SM00564 753 786 0.071 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c39230 eb92009dcccb437000f70f2400f08bef 832 SMART SM00564 232 264 4.6 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c39230 eb92009dcccb437000f70f2400f08bef 832 SMART SM00564 456 506 320.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c39230 eb92009dcccb437000f70f2400f08bef 832 SMART SM00564 383 425 1.0E-4 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c39230 eb92009dcccb437000f70f2400f08bef 832 Pfam PF01011 PQQ enzyme repeat 759 796 8.5E-6 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat MIM_c39230 eb92009dcccb437000f70f2400f08bef 832 Pfam PF01011 PQQ enzyme repeat 238 269 2.0E-5 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat MIM_c01950 f5f92358011089733b2eabcb196130ab 184 Pfam PF01799 [2Fe-2S] binding domain 84 167 1.8E-21 T 12-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 MIM_c01950 f5f92358011089733b2eabcb196130ab 184 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 11 70 1.2E-4 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MIM_c01950 f5f92358011089733b2eabcb196130ab 184 SUPERFAMILY SSF47741 100 171 3.01E-22 T 12-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily MIM_c01950 f5f92358011089733b2eabcb196130ab 184 Gene3D G3DSA:3.10.20.30 5 87 7.3E-20 T 12-10-2018 IPR012675 Beta-grasp domain superfamily MIM_c01950 f5f92358011089733b2eabcb196130ab 184 SUPERFAMILY SSF54292 7 88 7.21E-17 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MIM_c01950 f5f92358011089733b2eabcb196130ab 184 Gene3D G3DSA:1.10.150.120 94 176 1.2E-22 T 12-10-2018 MIM_c18970 32b4003e4947967c41ef9c9fd38b1b69 234 Gene3D G3DSA:3.40.50.300 4 229 3.5E-67 T 12-10-2018 MIM_c18970 32b4003e4947967c41ef9c9fd38b1b69 234 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c18970 32b4003e4947967c41ef9c9fd38b1b69 234 SUPERFAMILY SSF52540 7 226 3.51E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c18970 32b4003e4947967c41ef9c9fd38b1b69 234 Pfam PF00005 ABC transporter 27 170 1.5E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c18970 32b4003e4947967c41ef9c9fd38b1b69 234 SMART SM00382 35 228 9.9E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c11210 3168a2a39e7f4b4d9e2ed05c479d163e 326 Gene3D G3DSA:3.40.50.720 7 313 9.6E-92 T 12-10-2018 MIM_c11210 3168a2a39e7f4b4d9e2ed05c479d163e 326 SUPERFAMILY SSF52283 7 130 8.93E-16 T 12-10-2018 MIM_c11210 3168a2a39e7f4b4d9e2ed05c479d163e 326 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 117 294 2.4E-52 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MIM_c11210 3168a2a39e7f4b4d9e2ed05c479d163e 326 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 23 313 8.9E-8 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 MIM_c11210 3168a2a39e7f4b4d9e2ed05c479d163e 326 SUPERFAMILY SSF51735 109 295 3.45E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c11210 3168a2a39e7f4b4d9e2ed05c479d163e 326 Gene3D G3DSA:3.40.50.720 110 310 9.6E-92 T 12-10-2018 MIM_c03770 a5bac70ace95ff7aa965a9c358748926 323 SUPERFAMILY SSF53850 21 312 3.01E-67 T 12-10-2018 MIM_c03770 a5bac70ace95ff7aa965a9c358748926 323 PIRSF PIRSF002825 2 321 9.1E-66 T 12-10-2018 IPR026045 Ferric binding protein MIM_c03770 a5bac70ace95ff7aa965a9c358748926 323 Gene3D G3DSA:3.40.190.10 26 290 6.3E-74 T 12-10-2018 MIM_c03770 a5bac70ace95ff7aa965a9c358748926 323 Gene3D G3DSA:3.40.190.10 127 303 6.3E-74 T 12-10-2018 MIM_c03770 a5bac70ace95ff7aa965a9c358748926 323 Pfam PF13343 Bacterial extracellular solute-binding protein 75 302 2.9E-32 T 12-10-2018 MIM_c30310 3cfa535cae79d3845dc858bdc67e24a4 474 Gene3D G3DSA:2.20.200.10 107 361 5.3E-111 T 12-10-2018 MIM_c30310 3cfa535cae79d3845dc858bdc67e24a4 474 Gene3D G3DSA:1.20.1600.10 60 473 5.3E-111 T 12-10-2018 MIM_c30310 3cfa535cae79d3845dc858bdc67e24a4 474 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 11 472 1.7E-82 T 12-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 MIM_c30310 3cfa535cae79d3845dc858bdc67e24a4 474 SUPERFAMILY SSF56954 1 474 3.53E-92 T 12-10-2018 MIM_c30310 3cfa535cae79d3845dc858bdc67e24a4 474 Pfam PF02321 Outer membrane efflux protein 70 261 2.0E-23 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MIM_c30310 3cfa535cae79d3845dc858bdc67e24a4 474 Pfam PF02321 Outer membrane efflux protein 290 463 1.6E-20 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MIM_c16820 7aae38941cfe297f325500f10782b436 54 Gene3D G3DSA:2.20.28.10 1 53 9.5E-26 T 12-10-2018 MIM_c16820 7aae38941cfe297f325500f10782b436 54 PIRSF PIRSF000071 1 53 1.7E-22 T 12-10-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 MIM_c16820 7aae38941cfe297f325500f10782b436 54 PRINTS PR00163 Rubredoxin signature 3 19 8.0E-8 T 12-10-2018 IPR024935 Rubredoxin domain GO:0005506 MIM_c16820 7aae38941cfe297f325500f10782b436 54 PRINTS PR00163 Rubredoxin signature 33 49 8.0E-8 T 12-10-2018 IPR024935 Rubredoxin domain GO:0005506 MIM_c16820 7aae38941cfe297f325500f10782b436 54 Pfam PF00301 Rubredoxin 3 49 5.9E-22 T 12-10-2018 IPR024935 Rubredoxin domain GO:0005506 MIM_c16820 7aae38941cfe297f325500f10782b436 54 SUPERFAMILY SSF57802 2 52 1.04E-20 T 12-10-2018 MIM_c16820 7aae38941cfe297f325500f10782b436 54 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 12-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 MIM_c39470 8dbe2b0a132081d7b97840bf0189508a 357 SUPERFAMILY SSF89733 12 352 7.32E-88 T 12-10-2018 IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily GO:0016491|GO:0055114 MIM_c39470 8dbe2b0a132081d7b97840bf0189508a 357 Pfam PF02615 Malate/L-lactate dehydrogenase 14 338 1.5E-89 T 12-10-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0016491|GO:0055114 MIM_c39470 8dbe2b0a132081d7b97840bf0189508a 357 Gene3D G3DSA:3.30.1370.60 77 316 2.3E-89 T 12-10-2018 MIM_c39470 8dbe2b0a132081d7b97840bf0189508a 357 Gene3D G3DSA:1.10.1530.10 23 347 2.3E-89 T 12-10-2018 MIM_c38140 eb4c52cdbafbe4d0795025f62f148d7d 336 PIRSF PIRSF017082 4 336 3.5E-80 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c38140 eb4c52cdbafbe4d0795025f62f148d7d 336 SUPERFAMILY SSF53850 40 290 4.86E-14 T 12-10-2018 MIM_c38140 eb4c52cdbafbe4d0795025f62f148d7d 336 Gene3D G3DSA:3.40.190.10 136 261 1.0E-102 T 12-10-2018 MIM_c38140 eb4c52cdbafbe4d0795025f62f148d7d 336 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 57 332 6.3E-86 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c38140 eb4c52cdbafbe4d0795025f62f148d7d 336 Gene3D G3DSA:3.40.190.150 38 326 1.0E-102 T 12-10-2018 MIM_c11920 f316dce0b12fbdea5ad775f86d173a35 329 SUPERFAMILY SSF53850 118 292 2.61E-12 T 12-10-2018 MIM_c11920 f316dce0b12fbdea5ad775f86d173a35 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 325 6.3E-88 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c11920 f316dce0b12fbdea5ad775f86d173a35 329 Gene3D G3DSA:3.40.190.150 32 319 1.3E-112 T 12-10-2018 MIM_c11920 f316dce0b12fbdea5ad775f86d173a35 329 PIRSF PIRSF017082 1 328 5.9E-82 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c11920 f316dce0b12fbdea5ad775f86d173a35 329 Gene3D G3DSA:3.40.190.10 131 254 1.3E-112 T 12-10-2018 MIM_c12180 b54044ebb94bb0a0b59ca37d459e668f 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.132 T 12-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c12180 b54044ebb94bb0a0b59ca37d459e668f 89 Pfam PF00312 Ribosomal protein S15 8 88 1.0E-37 T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c12180 b54044ebb94bb0a0b59ca37d459e668f 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 6 89 6.2E-39 T 12-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c12180 b54044ebb94bb0a0b59ca37d459e668f 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 5.0E-30 T 12-10-2018 MIM_c12180 b54044ebb94bb0a0b59ca37d459e668f 89 SMART SM01387 8 88 3.3E-53 T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c12180 b54044ebb94bb0a0b59ca37d459e668f 89 Gene3D G3DSA:1.10.287.10 2 89 4.2E-35 T 12-10-2018 MIM_c12180 b54044ebb94bb0a0b59ca37d459e668f 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c12180 b54044ebb94bb0a0b59ca37d459e668f 89 SUPERFAMILY SSF47060 4 89 4.12E-35 T 12-10-2018 IPR009068 S15/NS1, RNA-binding MIM_c37550 38939687c01dec4fed78a76877b9304f 321 PIRSF PIRSF017082 2 320 9.0E-95 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c37550 38939687c01dec4fed78a76877b9304f 321 SUPERFAMILY SSF53850 112 279 3.12E-12 T 12-10-2018 MIM_c37550 38939687c01dec4fed78a76877b9304f 321 Gene3D G3DSA:3.40.190.10 124 246 6.7E-114 T 12-10-2018 MIM_c37550 38939687c01dec4fed78a76877b9304f 321 Gene3D G3DSA:3.40.190.150 28 311 6.7E-114 T 12-10-2018 MIM_c37550 38939687c01dec4fed78a76877b9304f 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 316 1.5E-86 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c39420 96d3ae43e003f661dcd19e5119200424 594 SUPERFAMILY SSF143975 4 379 2.75E-116 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MIM_c39420 96d3ae43e003f661dcd19e5119200424 594 Pfam PF00920 Dehydratase family 45 572 8.9E-155 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MIM_c39420 96d3ae43e003f661dcd19e5119200424 594 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 128 138 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MIM_c39420 96d3ae43e003f661dcd19e5119200424 594 SUPERFAMILY SSF52016 382 577 1.41E-45 T 12-10-2018 MIM_c39420 96d3ae43e003f661dcd19e5119200424 594 Gene3D G3DSA:3.50.30.80 382 547 3.1E-33 T 12-10-2018 MIM_c34780 82c1f0649f894605e27f9c40de302b7d 356 SUPERFAMILY SSF141571 23 164 7.32E-20 T 12-10-2018 MIM_c34780 82c1f0649f894605e27f9c40de302b7d 356 Pfam PF13599 Pentapeptide repeats (9 copies) 176 252 2.7E-11 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c34780 82c1f0649f894605e27f9c40de302b7d 356 Pfam PF13599 Pentapeptide repeats (9 copies) 30 91 5.4E-7 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c34780 82c1f0649f894605e27f9c40de302b7d 356 Gene3D G3DSA:2.160.20.80 257 356 7.2E-11 T 12-10-2018 MIM_c34780 82c1f0649f894605e27f9c40de302b7d 356 Pfam PF00805 Pentapeptide repeats (8 copies) 261 292 1.1E-4 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c34780 82c1f0649f894605e27f9c40de302b7d 356 Gene3D G3DSA:2.160.20.100 12 108 6.3E-20 T 12-10-2018 MIM_c34780 82c1f0649f894605e27f9c40de302b7d 356 SUPERFAMILY SSF141571 148 318 3.63E-36 T 12-10-2018 MIM_c34780 82c1f0649f894605e27f9c40de302b7d 356 Gene3D G3DSA:2.160.20.100 128 256 1.5E-26 T 12-10-2018 MIM_c08140 56b9478ee57e40e6d65cc89955969cd7 191 Gene3D G3DSA:1.20.1290.10 42 182 2.4E-26 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c08140 56b9478ee57e40e6d65cc89955969cd7 191 SUPERFAMILY SSF69118 7 178 3.12E-26 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c08140 56b9478ee57e40e6d65cc89955969cd7 191 Pfam PF02627 Carboxymuconolactone decarboxylase family 46 112 5.1E-6 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c24080 30e26954d0fa40e4b3541ae75785fe5c 291 Pfam PF01039 Carboxyl transferase domain 102 242 1.6E-15 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 MIM_c24080 30e26954d0fa40e4b3541ae75785fe5c 291 SUPERFAMILY SSF52096 27 284 2.61E-86 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c24080 30e26954d0fa40e4b3541ae75785fe5c 291 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 283 38.361 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MIM_c24080 30e26954d0fa40e4b3541ae75785fe5c 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 165 183 6.2E-39 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MIM_c24080 30e26954d0fa40e4b3541ae75785fe5c 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 202 219 6.2E-39 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MIM_c24080 30e26954d0fa40e4b3541ae75785fe5c 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 131 145 6.2E-39 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MIM_c24080 30e26954d0fa40e4b3541ae75785fe5c 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 253 262 6.2E-39 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MIM_c24080 30e26954d0fa40e4b3541ae75785fe5c 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 231 242 6.2E-39 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MIM_c24080 30e26954d0fa40e4b3541ae75785fe5c 291 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 285 1.3E-125 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MIM_c24080 30e26954d0fa40e4b3541ae75785fe5c 291 Gene3D G3DSA:3.90.226.10 27 288 1.0E-85 T 12-10-2018 MIM_c24990 74b11eea46d91c28749c672111b99501 260 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 13 197 0.0081 T 12-10-2018 MIM_c24990 74b11eea46d91c28749c672111b99501 260 Gene3D G3DSA:3.40.50.720 2 259 6.4E-79 T 12-10-2018 MIM_c24990 74b11eea46d91c28749c672111b99501 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 258 4.1E-55 T 12-10-2018 MIM_c24990 74b11eea46d91c28749c672111b99501 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 1.3E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c24990 74b11eea46d91c28749c672111b99501 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 1.3E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c24990 74b11eea46d91c28749c672111b99501 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 1.3E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c24990 74b11eea46d91c28749c672111b99501 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 1.2E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c24990 74b11eea46d91c28749c672111b99501 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 1.2E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c24990 74b11eea46d91c28749c672111b99501 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 1.2E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c24990 74b11eea46d91c28749c672111b99501 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 1.2E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c24990 74b11eea46d91c28749c672111b99501 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 1.2E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c24990 74b11eea46d91c28749c672111b99501 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 1.2E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c24990 74b11eea46d91c28749c672111b99501 260 SUPERFAMILY SSF51735 12 259 4.51E-75 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c24990 74b11eea46d91c28749c672111b99501 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 153 181 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c26150 bba621b544960fa2d31ab706afdc8ff1 1115 Pfam PF12705 PD-(D/E)XK nuclease superfamily 942 1086 2.2E-4 T 12-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type MIM_c26150 bba621b544960fa2d31ab706afdc8ff1 1115 Gene3D G3DSA:3.90.320.10 936 1106 6.0E-8 T 12-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal MIM_c26150 bba621b544960fa2d31ab706afdc8ff1 1115 Pfam PF13361 UvrD-like helicase C-terminal domain 749 852 5.4E-14 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MIM_c26150 bba621b544960fa2d31ab706afdc8ff1 1115 SUPERFAMILY SSF52980 936 1102 4.77E-8 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MIM_c26150 bba621b544960fa2d31ab706afdc8ff1 1115 Pfam PF13361 UvrD-like helicase C-terminal domain 475 662 1.3E-9 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MIM_c26150 bba621b544960fa2d31ab706afdc8ff1 1115 Pfam PF00580 UvrD/REP helicase N-terminal domain 15 462 1.5E-46 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 MIM_c26150 bba621b544960fa2d31ab706afdc8ff1 1115 Gene3D G3DSA:3.40.50.300 354 497 1.7E-29 T 12-10-2018 MIM_c26150 bba621b544960fa2d31ab706afdc8ff1 1115 Gene3D G3DSA:3.40.50.300 741 874 6.6E-22 T 12-10-2018 MIM_c26150 bba621b544960fa2d31ab706afdc8ff1 1115 SUPERFAMILY SSF52540 18 858 7.84E-89 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c26150 bba621b544960fa2d31ab706afdc8ff1 1115 Gene3D G3DSA:3.40.50.300 545 639 8.5E-12 T 12-10-2018 MIM_c34980 3833e94f1e2fe4a5d080aa6864b8d4d2 377 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 257 263 - T 12-10-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Reactome: R-HSA-9033241 MIM_c34980 3833e94f1e2fe4a5d080aa6864b8d4d2 377 Pfam PF01070 FMN-dependent dehydrogenase 34 360 2.5E-100 T 12-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 MIM_c34980 3833e94f1e2fe4a5d080aa6864b8d4d2 377 SUPERFAMILY SSF51395 26 359 7.33E-76 T 12-10-2018 MIM_c34980 3833e94f1e2fe4a5d080aa6864b8d4d2 377 PIRSF PIRSF000138 12 364 2.0E-101 T 12-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 MIM_c34980 3833e94f1e2fe4a5d080aa6864b8d4d2 377 Gene3D G3DSA:3.20.20.70 24 361 7.0E-103 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c37850 545b36154bab8e65a7987c7069315421 425 Pfam PF05159 Capsule polysaccharide biosynthesis protein 82 388 2.1E-85 T 12-10-2018 IPR007833 Capsule polysaccharide biosynthesis GO:0000271|GO:0015774 MIM_c03170 a6487a0e104133a08b8303a61c52534e 195 SUPERFAMILY SSF69118 14 191 4.76E-39 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c03170 a6487a0e104133a08b8303a61c52534e 195 Gene3D G3DSA:1.20.1290.10 77 194 1.6E-33 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c03170 a6487a0e104133a08b8303a61c52534e 195 TIGRFAM TIGR01926 peroxid_rel: uncharacterized peroxidase-related enzyme 19 193 1.8E-55 T 12-10-2018 IPR010195 Uncharacterised peroxidase-related MIM_c03170 a6487a0e104133a08b8303a61c52534e 195 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 75 104 2.6E-11 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c03170 a6487a0e104133a08b8303a61c52534e 195 Pfam PF02627 Carboxymuconolactone decarboxylase family 66 140 2.2E-13 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c06720 dd169926672784a0ea49298b3b5e294e 286 Pfam PF03099 Biotin/lipoate A/B protein ligase family 29 159 1.2E-11 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 MIM_c06720 dd169926672784a0ea49298b3b5e294e 286 Gene3D G3DSA:2.30.30.100 235 285 5.9E-12 T 12-10-2018 MIM_c06720 dd169926672784a0ea49298b3b5e294e 286 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 24 280 9.4E-35 T 12-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MIM_c06720 dd169926672784a0ea49298b3b5e294e 286 SUPERFAMILY SSF55681 22 231 9.77E-36 T 12-10-2018 MIM_c06720 dd169926672784a0ea49298b3b5e294e 286 Pfam PF02237 Biotin protein ligase C terminal domain 237 281 8.9E-6 T 12-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MIM_c06720 dd169926672784a0ea49298b3b5e294e 286 SUPERFAMILY SSF50037 236 281 3.34E-5 T 12-10-2018 IPR008988 Transcriptional repressor, C-terminal MIM_c06720 dd169926672784a0ea49298b3b5e294e 286 Gene3D G3DSA:3.30.930.10 9 233 2.6E-43 T 12-10-2018 MIM_c28370 1e934c965d6932f9c2a05c09e7055811 272 SUPERFAMILY SSF161098 49 247 3.27E-37 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c28370 1e934c965d6932f9c2a05c09e7055811 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 70 260 2.6E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c28370 1e934c965d6932f9c2a05c09e7055811 272 Gene3D G3DSA:1.10.3720.10 40 267 3.2E-46 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c28370 1e934c965d6932f9c2a05c09e7055811 272 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 48 156 1.1E-18 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c27300 5d53fcf9d700561c68c10503d402b7b4 186 SUPERFAMILY SSF55729 17 175 1.95E-22 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c27300 5d53fcf9d700561c68c10503d402b7b4 186 Pfam PF00583 Acetyltransferase (GNAT) family 46 152 1.0E-8 T 12-10-2018 IPR000182 GNAT domain MIM_c27300 5d53fcf9d700561c68c10503d402b7b4 186 Gene3D G3DSA:3.40.630.30 5 182 7.2E-21 T 12-10-2018 MIM_c20980 53ee0319679a62db772cec1f8fd1b247 553 Pfam PF05199 GMC oxidoreductase 391 525 3.9E-36 T 12-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 MIM_c20980 53ee0319679a62db772cec1f8fd1b247 553 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 255 269 - T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c20980 53ee0319679a62db772cec1f8fd1b247 553 SUPERFAMILY SSF51905 4 535 7.12E-82 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c20980 53ee0319679a62db772cec1f8fd1b247 553 Gene3D G3DSA:1.10.1220.110 98 151 6.0E-169 T 12-10-2018 MIM_c20980 53ee0319679a62db772cec1f8fd1b247 553 Gene3D G3DSA:4.10.450.10 39 197 6.0E-169 T 12-10-2018 IPR027424 Glucose Oxidase, domain 2 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 MIM_c20980 53ee0319679a62db772cec1f8fd1b247 553 Pfam PF00732 GMC oxidoreductase 6 296 3.6E-81 T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c20980 53ee0319679a62db772cec1f8fd1b247 553 SUPERFAMILY SSF54373 291 477 8.24E-42 T 12-10-2018 MIM_c20980 53ee0319679a62db772cec1f8fd1b247 553 Gene3D G3DSA:3.50.50.60 5 531 6.0E-169 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c20980 53ee0319679a62db772cec1f8fd1b247 553 Gene3D G3DSA:3.30.410.40 152 474 6.0E-169 T 12-10-2018 MIM_c20980 53ee0319679a62db772cec1f8fd1b247 553 PIRSF PIRSF000137 1 537 2.8E-143 T 12-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c13650 b54e557b9b02e8718ea1b5cbfd36c483 210 SUPERFAMILY SSF102114 45 137 1.24E-8 T 12-10-2018 MIM_c13650 b54e557b9b02e8718ea1b5cbfd36c483 210 Pfam PF13394 4Fe-4S single cluster domain 25 122 2.1E-6 T 12-10-2018 MIM_c13650 b54e557b9b02e8718ea1b5cbfd36c483 210 PIRSF PIRSF000370 1 210 8.3E-37 T 12-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 MIM_c13650 b54e557b9b02e8718ea1b5cbfd36c483 210 Pfam PF04055 Radical SAM superfamily 45 122 3.6E-7 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MIM_c13650 b54e557b9b02e8718ea1b5cbfd36c483 210 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 210 32.773 T 12-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 MIM_c13650 b54e557b9b02e8718ea1b5cbfd36c483 210 Gene3D G3DSA:3.20.20.70 2 210 6.7E-70 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c13650 b54e557b9b02e8718ea1b5cbfd36c483 210 TIGRFAM TIGR04508 queE_Cx14CxxC: 7-carboxy-7-deazaguanine synthase 3 210 1.6E-108 T 12-10-2018 IPR030977 7-carboxy-7-deazaguanine synthase, Cx14CxxC-type GO:0008616|GO:0046872 KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 MIM_c00080 a7620e549fef1596cdfcad113bce0477 162 Pfam PF03974 Ecotin 34 150 3.1E-27 T 12-10-2018 IPR005658 Proteinase inhibitor I11, ecotin MIM_c00080 a7620e549fef1596cdfcad113bce0477 162 SUPERFAMILY SSF49772 37 158 7.06E-17 T 12-10-2018 IPR036198 Ecotin superfamily MIM_c00080 a7620e549fef1596cdfcad113bce0477 162 Gene3D G3DSA:2.60.40.550 25 161 3.8E-25 T 12-10-2018 MIM_c19780 4130b889d878abc57601b87114a10492 206 SMART SM00478 50 200 1.3E-4 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MIM_c19780 4130b889d878abc57601b87114a10492 206 Gene3D G3DSA:1.10.340.30 36 148 8.6E-69 T 12-10-2018 MIM_c19780 4130b889d878abc57601b87114a10492 206 Gene3D G3DSA:1.10.1670.40 8 198 8.6E-69 T 12-10-2018 MIM_c19780 4130b889d878abc57601b87114a10492 206 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 44 182 4.6E-14 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MIM_c19780 4130b889d878abc57601b87114a10492 206 SUPERFAMILY SSF48150 37 198 2.09E-36 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MIM_c13150 215e9a0109aca8246537839fb74bb0b6 803 Gene3D G3DSA:1.25.40.310 15 103 1.6E-33 T 12-10-2018 IPR036288 Aconitase B, HEAT-like domain superfamily GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MIM_c13150 215e9a0109aca8246537839fb74bb0b6 803 Pfam PF11791 Aconitate B N-terminal domain 18 98 2.7E-31 T 12-10-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MIM_c13150 215e9a0109aca8246537839fb74bb0b6 803 TIGRFAM TIGR00117 acnB: aconitate hydratase 2 19 796 0.0 T 12-10-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MIM_c13150 215e9a0109aca8246537839fb74bb0b6 803 SUPERFAMILY SSF52016 104 312 7.06E-66 T 12-10-2018 MIM_c13150 215e9a0109aca8246537839fb74bb0b6 803 Gene3D G3DSA:3.40.1060.10 325 624 4.5E-151 T 12-10-2018 IPR015932 Aconitase, domain 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MIM_c13150 215e9a0109aca8246537839fb74bb0b6 803 Gene3D G3DSA:3.30.499.10 345 472 4.5E-151 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 MIM_c13150 215e9a0109aca8246537839fb74bb0b6 803 Gene3D G3DSA:3.30.499.10 626 803 4.1E-64 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 MIM_c13150 215e9a0109aca8246537839fb74bb0b6 803 Pfam PF00330 Aconitase family (aconitate hydratase) 414 757 6.2E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c13150 215e9a0109aca8246537839fb74bb0b6 803 Gene3D G3DSA:3.20.19.10 104 301 2.5E-74 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 MIM_c13150 215e9a0109aca8246537839fb74bb0b6 803 Pfam PF06434 Aconitate hydratase 2 N-terminus 110 322 2.0E-96 T 12-10-2018 IPR015929 Aconitase B, swivel GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MIM_c13150 215e9a0109aca8246537839fb74bb0b6 803 SUPERFAMILY SSF74778 18 102 1.44E-33 T 12-10-2018 IPR036288 Aconitase B, HEAT-like domain superfamily GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MIM_c13150 215e9a0109aca8246537839fb74bb0b6 803 ProSitePatterns PS00450 Aconitase family signature 1. 645 662 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MIM_c13150 215e9a0109aca8246537839fb74bb0b6 803 SUPERFAMILY SSF53732 319 796 5.76E-146 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 MIM_c11460 095d1f8d7961640a0f113205292d3fb1 337 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 337 79.849 T 12-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MIM_c11460 095d1f8d7961640a0f113205292d3fb1 337 Gene3D G3DSA:3.30.43.10 4 70 3.2E-11 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 MIM_c11460 095d1f8d7961640a0f113205292d3fb1 337 Gene3D G3DSA:3.30.465.10 73 225 8.7E-55 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MIM_c11460 095d1f8d7961640a0f113205292d3fb1 337 SUPERFAMILY SSF56194 209 336 8.5E-47 T 12-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MIM_c11460 095d1f8d7961640a0f113205292d3fb1 337 SUPERFAMILY SSF56176 9 196 1.45E-42 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MIM_c11460 095d1f8d7961640a0f113205292d3fb1 337 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 13 332 9.5E-71 T 12-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MIM_c11460 095d1f8d7961640a0f113205292d3fb1 337 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 213 335 8.5E-34 T 12-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MIM_c11460 095d1f8d7961640a0f113205292d3fb1 337 Gene3D G3DSA:3.90.78.10 226 337 3.0E-41 T 12-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MIM_c11460 095d1f8d7961640a0f113205292d3fb1 337 Pfam PF01565 FAD binding domain 22 150 2.1E-19 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MIM_c24120 03ebe576c52f5d3d6111a5a2f18fd1cb 169 SUPERFAMILY SSF52218 9 166 3.65E-19 T 12-10-2018 IPR029039 Flavoprotein-like superfamily MIM_c24120 03ebe576c52f5d3d6111a5a2f18fd1cb 169 Pfam PF03358 NADPH-dependent FMN reductase 57 121 1.1E-5 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 MIM_c24120 03ebe576c52f5d3d6111a5a2f18fd1cb 169 Gene3D G3DSA:3.40.50.360 7 169 7.3E-14 T 12-10-2018 IPR029039 Flavoprotein-like superfamily MIM_c16190 eaa15ffa4a06daa1ec34fd22df242d59 184 SUPERFAMILY SSF69118 1 175 1.57E-26 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c16190 eaa15ffa4a06daa1ec34fd22df242d59 184 Gene3D G3DSA:1.20.1290.10 13 177 6.5E-25 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c16190 eaa15ffa4a06daa1ec34fd22df242d59 184 Pfam PF02627 Carboxymuconolactone decarboxylase family 42 105 4.0E-7 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c04080 d684203dc85117c3bdc75f58797118d4 368 SUPERFAMILY SSF56634 36 348 6.8E-88 T 12-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c04080 d684203dc85117c3bdc75f58797118d4 368 Gene3D G3DSA:1.20.1280.120 55 344 7.7E-103 T 12-10-2018 MIM_c04080 d684203dc85117c3bdc75f58797118d4 368 Gene3D G3DSA:2.40.180.20 74 330 7.7E-103 T 12-10-2018 MIM_c04080 d684203dc85117c3bdc75f58797118d4 368 PIRSF PIRSF000296 17 351 2.5E-113 T 12-10-2018 IPR024168 Catalase, SrpA-type, predicted MIM_c04080 d684203dc85117c3bdc75f58797118d4 368 SMART SM01060 49 368 1.1E-6 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c04080 d684203dc85117c3bdc75f58797118d4 368 Pfam PF00199 Catalase 68 345 7.7E-26 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c16740 3dce9bfbb32563113f25e966d2ae8363 270 PIRSF PIRSF001430 2 259 7.8E-76 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MIM_c16740 3dce9bfbb32563113f25e966d2ae8363 270 Gene3D G3DSA:3.30.70.580 1 106 1.5E-37 T 12-10-2018 MIM_c16740 3dce9bfbb32563113f25e966d2ae8363 270 Gene3D G3DSA:3.30.70.660 107 243 7.3E-45 T 12-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 MIM_c16740 3dce9bfbb32563113f25e966d2ae8363 270 SUPERFAMILY SSF55120 3 251 5.61E-89 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MIM_c16740 3dce9bfbb32563113f25e966d2ae8363 270 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 3 245 33.608 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MIM_c16740 3dce9bfbb32563113f25e966d2ae8363 270 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 3 239 1.5E-67 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MIM_c16740 3dce9bfbb32563113f25e966d2ae8363 270 Pfam PF01416 tRNA pseudouridine synthase 144 246 2.0E-28 T 12-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MIM_c16740 3dce9bfbb32563113f25e966d2ae8363 270 Pfam PF01416 tRNA pseudouridine synthase 10 104 1.6E-6 T 12-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MIM_c36290 1866c0936c8df4ec7456e0eb44c07867 451 Gene3D G3DSA:2.60.120.10 282 419 7.7E-64 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c36290 1866c0936c8df4ec7456e0eb44c07867 451 Pfam PF04209 homogentisate 1,2-dioxygenase 24 449 4.7E-195 T 12-10-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 MIM_c36290 1866c0936c8df4ec7456e0eb44c07867 451 TIGRFAM TIGR01015 hmgA: homogentisate 1,2-dioxygenase 22 449 2.5E-192 T 12-10-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 MIM_c36290 1866c0936c8df4ec7456e0eb44c07867 451 SUPERFAMILY SSF51182 23 450 5.6E-158 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c27250 fb4697ea9e9e07e1f34ba8bdcd5469c2 258 SUPERFAMILY SSF52540 5 247 6.35E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c27250 fb4697ea9e9e07e1f34ba8bdcd5469c2 258 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 246 1.1E-7 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal MIM_c27250 fb4697ea9e9e07e1f34ba8bdcd5469c2 258 SMART SM00382 30 224 3.4E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c27250 fb4697ea9e9e07e1f34ba8bdcd5469c2 258 Gene3D G3DSA:3.40.50.300 4 251 1.5E-55 T 12-10-2018 MIM_c27250 fb4697ea9e9e07e1f34ba8bdcd5469c2 258 Pfam PF00005 ABC transporter 22 176 6.6E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c16880 c1f5bc01b06a8186b434b10f98a37a02 400 TIGRFAM TIGR03538 DapC_gpp: succinyldiaminopimelate transaminase 1 394 7.4E-187 T 12-10-2018 IPR019878 Succinyldiaminopimelate transaminase, DapC, beta/gammaproteobacteria GO:0009016|GO:0009089 MIM_c16880 c1f5bc01b06a8186b434b10f98a37a02 400 SUPERFAMILY SSF53383 2 396 2.53E-79 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c16880 c1f5bc01b06a8186b434b10f98a37a02 400 Gene3D G3DSA:3.90.1150.10 13 382 3.1E-107 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c16880 c1f5bc01b06a8186b434b10f98a37a02 400 Gene3D G3DSA:3.40.640.10 44 291 3.1E-107 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c16880 c1f5bc01b06a8186b434b10f98a37a02 400 Pfam PF00155 Aminotransferase class I and II 33 376 8.1E-40 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MIM_c14870 c3b2dfa0868c17c4b6158d754dc310d6 460 SUPERFAMILY SSF52540 190 442 4.86E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c14870 c3b2dfa0868c17c4b6158d754dc310d6 460 Pfam PF03796 DnaB-like helicase C terminal domain 192 449 4.1E-112 T 12-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 MIM_c14870 c3b2dfa0868c17c4b6158d754dc310d6 460 SUPERFAMILY SSF48024 12 123 3.79E-34 T 12-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 MIM_c14870 c3b2dfa0868c17c4b6158d754dc310d6 460 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 13 451 1.2E-168 T 12-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 MIM_c14870 c3b2dfa0868c17c4b6158d754dc310d6 460 Gene3D G3DSA:3.40.50.300 171 452 3.3E-101 T 12-10-2018 MIM_c14870 c3b2dfa0868c17c4b6158d754dc310d6 460 Gene3D G3DSA:1.10.860.10 7 170 1.1E-49 T 12-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal MIM_c14870 c3b2dfa0868c17c4b6158d754dc310d6 460 SMART SM00382 209 409 0.0055 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c14870 c3b2dfa0868c17c4b6158d754dc310d6 460 Pfam PF00772 DnaB-like helicase N terminal domain 14 115 4.4E-32 T 12-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 MIM_c00660 badc6a8ea7bbe1d8046f7fa0d970ad2c 636 SUPERFAMILY SSF49785 58 128 1.19E-6 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily MIM_c00660 badc6a8ea7bbe1d8046f7fa0d970ad2c 636 Gene3D G3DSA:2.60.120.260 34 137 4.1E-5 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily MIM_c00660 badc6a8ea7bbe1d8046f7fa0d970ad2c 636 Pfam PF07730 Histidine kinase 436 479 6.7E-5 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MIM_c00660 badc6a8ea7bbe1d8046f7fa0d970ad2c 636 Gene3D G3DSA:3.30.565.10 507 629 2.5E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c00660 badc6a8ea7bbe1d8046f7fa0d970ad2c 636 SUPERFAMILY SSF55874 504 623 9.31E-12 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c00660 badc6a8ea7bbe1d8046f7fa0d970ad2c 636 SMART SM00387 537 631 4.0E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c35340 c814fee7c69a080745e4422e9d589df4 200 Gene3D G3DSA:1.10.357.10 70 199 5.6E-31 T 12-10-2018 MIM_c35340 c814fee7c69a080745e4422e9d589df4 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 8.8E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c35340 c814fee7c69a080745e4422e9d589df4 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 8.8E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c35340 c814fee7c69a080745e4422e9d589df4 200 SUPERFAMILY SSF48498 81 196 7.12E-26 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MIM_c35340 c814fee7c69a080745e4422e9d589df4 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 8.0E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c35340 c814fee7c69a080745e4422e9d589df4 200 Gene3D G3DSA:1.10.10.60 2 68 4.9E-29 T 12-10-2018 MIM_c35340 c814fee7c69a080745e4422e9d589df4 200 SUPERFAMILY SSF46689 2 84 2.29E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c36560 c7c1bc96a02d0c9029100ca5095b6ebb 559 Gene3D G3DSA:3.10.310.70 87 217 2.7E-105 T 12-10-2018 MIM_c36560 c7c1bc96a02d0c9029100ca5095b6ebb 559 Pfam PF07969 Amidohydrolase family 62 551 1.2E-77 T 12-10-2018 IPR013108 Amidohydrolase 3 MIM_c36560 c7c1bc96a02d0c9029100ca5095b6ebb 559 SUPERFAMILY SSF51556 67 513 1.13E-34 T 12-10-2018 IPR032466 Metal-dependent hydrolase MIM_c36560 c7c1bc96a02d0c9029100ca5095b6ebb 559 SUPERFAMILY SSF51338 19 552 1.27E-11 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MIM_c36560 c7c1bc96a02d0c9029100ca5095b6ebb 559 Gene3D G3DSA:2.30.40.10 19 530 2.7E-105 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MIM_c36560 c7c1bc96a02d0c9029100ca5095b6ebb 559 Gene3D G3DSA:3.20.20.140 68 512 2.7E-105 T 12-10-2018 MIM_c30400 9ff2408b64ff4613d6877abf27820e8c 415 SUPERFAMILY SSF51905 33 404 8.05E-57 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c30400 9ff2408b64ff4613d6877abf27820e8c 415 Gene3D G3DSA:3.30.9.10 116 345 2.4E-116 T 12-10-2018 MIM_c30400 9ff2408b64ff4613d6877abf27820e8c 415 TIGRFAM TIGR01373 soxB: sarcosine oxidase, beta subunit family 4 407 2.1E-215 T 12-10-2018 IPR006278 Sarcosine oxidase subunit beta GO:0008115|GO:0046653|GO:0055114 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 MIM_c30400 9ff2408b64ff4613d6877abf27820e8c 415 Gene3D G3DSA:3.50.50.60 35 389 2.4E-116 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c30400 9ff2408b64ff4613d6877abf27820e8c 415 Pfam PF01266 FAD dependent oxidoreductase 35 379 6.9E-63 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MIM_c17160 0818fd8c33ef98491e04e9b380b8b1cd 157 Pfam PF07080 Protein of unknown function (DUF1348) 10 139 3.4E-68 T 12-10-2018 IPR009783 Protein of unknown function DUF1348 MIM_c17160 0818fd8c33ef98491e04e9b380b8b1cd 157 Gene3D G3DSA:3.10.450.50 13 157 1.0E-78 T 12-10-2018 MIM_c17160 0818fd8c33ef98491e04e9b380b8b1cd 157 SUPERFAMILY SSF54427 4 157 1.07E-81 T 12-10-2018 IPR032710 NTF2-like domain superfamily MIM_c36120 9873a31c8b04b8b49053ab376ce6c1ec 255 Pfam PF01614 Bacterial transcriptional regulator 120 242 4.1E-31 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal MIM_c36120 9873a31c8b04b8b49053ab376ce6c1ec 255 SUPERFAMILY SSF46785 4 75 1.69E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c36120 9873a31c8b04b8b49053ab376ce6c1ec 255 Gene3D G3DSA:1.10.10.10 3 73 6.5E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c36120 9873a31c8b04b8b49053ab376ce6c1ec 255 Pfam PF09339 IclR helix-turn-helix domain 5 56 9.3E-13 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c36120 9873a31c8b04b8b49053ab376ce6c1ec 255 Gene3D G3DSA:3.30.450.40 74 253 3.6E-57 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c36120 9873a31c8b04b8b49053ab376ce6c1ec 255 SMART SM00346 2 92 4.0E-15 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c36120 9873a31c8b04b8b49053ab376ce6c1ec 255 SUPERFAMILY SSF55781 74 246 7.85E-51 T 12-10-2018 MIM_c16090 bfc8fece8df096c14d147ca4bcb9ea2b 295 SUPERFAMILY SSF53850 90 293 5.21E-38 T 12-10-2018 MIM_c16090 bfc8fece8df096c14d147ca4bcb9ea2b 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 2.9E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c16090 bfc8fece8df096c14d147ca4bcb9ea2b 295 Pfam PF03466 LysR substrate binding domain 89 292 3.0E-35 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c16090 bfc8fece8df096c14d147ca4bcb9ea2b 295 SUPERFAMILY SSF46785 1 112 5.03E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c16090 bfc8fece8df096c14d147ca4bcb9ea2b 295 Gene3D G3DSA:1.10.10.10 3 90 1.7E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c16090 bfc8fece8df096c14d147ca4bcb9ea2b 295 Gene3D G3DSA:3.40.190.290 92 294 4.9E-35 T 12-10-2018 MIM_c40060 c91cc976e2425d9d7df9401c01f5bca4 701 PRINTS PR00315 GTP-binding elongation factor signature 101 112 4.3E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c40060 c91cc976e2425d9d7df9401c01f5bca4 701 PRINTS PR00315 GTP-binding elongation factor signature 137 146 4.3E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c40060 c91cc976e2425d9d7df9401c01f5bca4 701 PRINTS PR00315 GTP-binding elongation factor signature 85 95 4.3E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c40060 c91cc976e2425d9d7df9401c01f5bca4 701 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.3E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c40060 c91cc976e2425d9d7df9401c01f5bca4 701 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.3E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c40060 c91cc976e2425d9d7df9401c01f5bca4 701 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 187 1.5E-30 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MIM_c40060 c91cc976e2425d9d7df9401c01f5bca4 701 Gene3D G3DSA:3.30.230.10 489 695 1.6E-88 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MIM_c40060 c91cc976e2425d9d7df9401c01f5bca4 701 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 700 0.0 T 12-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MIM_c40060 c91cc976e2425d9d7df9401c01f5bca4 701 Gene3D G3DSA:3.40.50.300 1 293 4.0E-114 T 12-10-2018 MIM_c40060 c91cc976e2425d9d7df9401c01f5bca4 701 Pfam PF00679 Elongation factor G C-terminus 607 694 2.8E-31 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like MIM_c40060 c91cc976e2425d9d7df9401c01f5bca4 701 SUPERFAMILY SSF50447 271 409 1.97E-36 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MIM_c40060 c91cc976e2425d9d7df9401c01f5bca4 701 Gene3D G3DSA:2.40.30.10 294 421 2.7E-51 T 12-10-2018 MIM_c40060 c91cc976e2425d9d7df9401c01f5bca4 701 SUPERFAMILY SSF52540 6 288 7.22E-108 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c40060 c91cc976e2425d9d7df9401c01f5bca4 701 SUPERFAMILY SSF54980 610 697 8.15E-29 T 12-10-2018 IPR035647 EF-G domain III/V-like MIM_c40060 c91cc976e2425d9d7df9401c01f5bca4 701 SMART SM00838 607 695 1.2E-55 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like MIM_c40060 c91cc976e2425d9d7df9401c01f5bca4 701 SUPERFAMILY SSF54980 409 486 7.55E-25 T 12-10-2018 IPR035647 EF-G domain III/V-like MIM_c40060 c91cc976e2425d9d7df9401c01f5bca4 701 Pfam PF00009 Elongation factor Tu GTP binding domain 9 288 7.7E-65 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c40060 c91cc976e2425d9d7df9401c01f5bca4 701 Gene3D G3DSA:3.30.70.240 611 682 1.6E-88 T 12-10-2018 MIM_c40060 c91cc976e2425d9d7df9401c01f5bca4 701 Pfam PF14492 Elongation Factor G, domain II 409 483 7.8E-34 T 12-10-2018 MIM_c40060 c91cc976e2425d9d7df9401c01f5bca4 701 Pfam PF03144 Elongation factor Tu domain 2 329 396 2.8E-18 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MIM_c40060 c91cc976e2425d9d7df9401c01f5bca4 701 SMART SM00889 485 605 9.5E-77 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 MIM_c40060 c91cc976e2425d9d7df9401c01f5bca4 701 Pfam PF03764 Elongation factor G, domain IV 484 605 5.0E-48 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 MIM_c40060 c91cc976e2425d9d7df9401c01f5bca4 701 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site MIM_c40060 c91cc976e2425d9d7df9401c01f5bca4 701 SUPERFAMILY SSF54211 484 605 3.79E-43 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MIM_c40060 c91cc976e2425d9d7df9401c01f5bca4 701 Gene3D G3DSA:3.30.70.870 438 488 5.5E-26 T 12-10-2018 MIM_c40060 c91cc976e2425d9d7df9401c01f5bca4 701 Hamap MF_00054_B Elongation factor G [fusA]. 6 699 112.508 T 12-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MIM_c36640 58c490afa1611554e88a40d98b49e7e4 270 SUPERFAMILY SSF52540 8 230 2.16E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c36640 58c490afa1611554e88a40d98b49e7e4 270 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c36640 58c490afa1611554e88a40d98b49e7e4 270 Pfam PF00005 ABC transporter 29 169 9.5E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c36640 58c490afa1611554e88a40d98b49e7e4 270 Gene3D G3DSA:3.40.50.300 6 253 8.4E-55 T 12-10-2018 MIM_c36640 58c490afa1611554e88a40d98b49e7e4 270 SMART SM00382 38 228 3.7E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c03640 0436d3de3f4ab0b54224a192958ba41a 619 SUPERFAMILY SSF46785 313 416 9.26E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c03640 0436d3de3f4ab0b54224a192958ba41a 619 Gene3D G3DSA:3.40.190.290 408 617 1.3E-22 T 12-10-2018 MIM_c03640 0436d3de3f4ab0b54224a192958ba41a 619 SUPERFAMILY SSF53850 424 612 1.07E-26 T 12-10-2018 MIM_c03640 0436d3de3f4ab0b54224a192958ba41a 619 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 317 377 3.2E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c03640 0436d3de3f4ab0b54224a192958ba41a 619 SUPERFAMILY SSF46785 8 64 6.72E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c03640 0436d3de3f4ab0b54224a192958ba41a 619 Gene3D G3DSA:1.10.10.10 313 406 1.3E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c03640 0436d3de3f4ab0b54224a192958ba41a 619 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 332 343 3.2E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c03640 0436d3de3f4ab0b54224a192958ba41a 619 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 353 364 3.2E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c03640 0436d3de3f4ab0b54224a192958ba41a 619 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 343 353 3.2E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c03640 0436d3de3f4ab0b54224a192958ba41a 619 Pfam PF03466 LysR substrate binding domain 408 612 7.3E-26 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c39080 799438cd4d6ce19dd9c455f804f006ce 109 Gene3D G3DSA:2.30.30.30 2 103 8.2E-34 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 MIM_c39080 799438cd4d6ce19dd9c455f804f006ce 109 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 2 96 19.053 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c39080 799438cd4d6ce19dd9c455f804f006ce 109 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 101 2.4E-23 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c39080 799438cd4d6ce19dd9c455f804f006ce 109 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 2 102 5.7E-30 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c39080 799438cd4d6ce19dd9c455f804f006ce 109 SUPERFAMILY SSF50104 3 101 9.53E-30 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily MIM_c39080 799438cd4d6ce19dd9c455f804f006ce 109 ProSitePatterns PS01108 Ribosomal protein L24 signature. 7 24 - T 12-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c19230 36fea768110f90c77aeb320f802ac462 434 SUPERFAMILY SSF53623 9 288 6.98E-88 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MIM_c19230 36fea768110f90c77aeb320f802ac462 434 PIRSF PIRSF001563 4 432 7.9E-106 T 12-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 MIM_c19230 36fea768110f90c77aeb320f802ac462 434 TIGRFAM TIGR01499 folC: bifunctional protein FolC 30 428 2.7E-102 T 12-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 MIM_c19230 36fea768110f90c77aeb320f802ac462 434 Gene3D G3DSA:3.90.190.20 292 431 7.2E-30 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MIM_c19230 36fea768110f90c77aeb320f802ac462 434 Pfam PF08245 Mur ligase middle domain 52 266 9.3E-12 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MIM_c19230 36fea768110f90c77aeb320f802ac462 434 Gene3D G3DSA:3.40.1190.10 2 291 4.5E-91 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MIM_c19230 36fea768110f90c77aeb320f802ac462 434 SUPERFAMILY SSF53244 290 429 5.13E-29 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MIM_c35280 1e9f45df4a31f042e543801104934619 570 Pfam PF17287 POTRA domain 156 210 5.6E-19 T 12-10-2018 IPR035251 ShlB, POTRA domain MIM_c35280 1e9f45df4a31f042e543801104934619 570 Gene3D G3DSA:2.40.160.50 188 570 1.7E-104 T 12-10-2018 MIM_c35280 1e9f45df4a31f042e543801104934619 570 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 215 533 1.1E-109 T 12-10-2018 IPR005565 Haemolysin activator HlyB, C-terminal MIM_c35280 1e9f45df4a31f042e543801104934619 570 Pfam PF08479 POTRA domain, ShlB-type 70 155 2.6E-14 T 12-10-2018 IPR013686 Polypeptide-transport-associated, ShlB-type MIM_c35280 1e9f45df4a31f042e543801104934619 570 PIRSF PIRSF029745 2 570 7.3E-155 T 12-10-2018 IPR027282 Two partner secretion pathway transporter GO:0015031 MIM_c00280 bc57fc133290145c5ec6dac9c8e5480e 349 Gene3D G3DSA:3.20.20.140 31 347 3.3E-68 T 12-10-2018 MIM_c00280 bc57fc133290145c5ec6dac9c8e5480e 349 Pfam PF04909 Amidohydrolase 34 343 5.4E-22 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MIM_c00280 bc57fc133290145c5ec6dac9c8e5480e 349 SUPERFAMILY SSF51556 32 344 1.24E-37 T 12-10-2018 IPR032466 Metal-dependent hydrolase MIM_c15510 6af1e6205b044ece074a94d9bbfe623f 303 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 13 272 2.4E-120 T 12-10-2018 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 MIM_c15510 6af1e6205b044ece074a94d9bbfe623f 303 SUPERFAMILY SSF161098 10 263 1.78E-52 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c15510 6af1e6205b044ece074a94d9bbfe623f 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 269 3.5E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c15510 6af1e6205b044ece074a94d9bbfe623f 303 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 13 270 1.6E-95 T 12-10-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 MIM_c15510 6af1e6205b044ece074a94d9bbfe623f 303 Gene3D G3DSA:1.10.3720.10 14 274 7.0E-61 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c27160 26773e8f51f416f8dfcf0dd89736c10c 423 SUPERFAMILY SSF63380 130 273 8.23E-38 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MIM_c27160 26773e8f51f416f8dfcf0dd89736c10c 423 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 50 61 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MIM_c27160 26773e8f51f416f8dfcf0dd89736c10c 423 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 21 32 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MIM_c27160 26773e8f51f416f8dfcf0dd89736c10c 423 SUPERFAMILY SSF52343 269 423 4.32E-34 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MIM_c27160 26773e8f51f416f8dfcf0dd89736c10c 423 Pfam PF00175 Oxidoreductase NAD-binding domain 281 390 1.4E-13 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MIM_c27160 26773e8f51f416f8dfcf0dd89736c10c 423 Gene3D G3DSA:2.40.30.10 126 265 7.4E-38 T 12-10-2018 MIM_c27160 26773e8f51f416f8dfcf0dd89736c10c 423 Gene3D G3DSA:3.30.70.20 6 68 1.4E-12 T 12-10-2018 MIM_c27160 26773e8f51f416f8dfcf0dd89736c10c 423 TIGRFAM TIGR03224 benzo_boxA: benzoyl-CoA oxygenase/reductase, BoxA protein 10 423 1.3E-213 T 12-10-2018 IPR017634 Benzoyl-CoA oxygenase/reductase, BoxA protein KEGG: 00362+1.14.13.208|MetaCyc: PWY-1361 MIM_c27160 26773e8f51f416f8dfcf0dd89736c10c 423 Gene3D G3DSA:3.40.50.80 266 423 2.1E-35 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MIM_c27160 26773e8f51f416f8dfcf0dd89736c10c 423 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 244 253 6.8E-19 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MIM_c27160 26773e8f51f416f8dfcf0dd89736c10c 423 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 311 320 6.8E-19 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MIM_c27160 26773e8f51f416f8dfcf0dd89736c10c 423 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 377 385 6.8E-19 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MIM_c27160 26773e8f51f416f8dfcf0dd89736c10c 423 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 185 195 6.8E-19 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MIM_c27160 26773e8f51f416f8dfcf0dd89736c10c 423 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 353 369 6.8E-19 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MIM_c27160 26773e8f51f416f8dfcf0dd89736c10c 423 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 280 299 6.8E-19 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MIM_c27160 26773e8f51f416f8dfcf0dd89736c10c 423 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 208 215 6.8E-19 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MIM_c27160 26773e8f51f416f8dfcf0dd89736c10c 423 Pfam PF12838 4Fe-4S dicluster domain 21 64 9.8E-7 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MIM_c27160 26773e8f51f416f8dfcf0dd89736c10c 423 PIRSF PIRSF000361 71 423 3.5E-68 T 12-10-2018 IPR015701 Ferredoxin--NADP reductase GO:0016491|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 MIM_c27160 26773e8f51f416f8dfcf0dd89736c10c 423 SUPERFAMILY SSF54862 15 75 1.48E-19 T 12-10-2018 MIM_c27160 26773e8f51f416f8dfcf0dd89736c10c 423 PIRSF PIRSF501177 1 423 2.5E-211 T 12-10-2018 IPR017634 Benzoyl-CoA oxygenase/reductase, BoxA protein KEGG: 00362+1.14.13.208|MetaCyc: PWY-1361 MIM_c25780 db013d637acbe1ee5b44fb7453d24c72 316 Gene3D G3DSA:3.40.190.10 163 259 6.8E-42 T 12-10-2018 MIM_c25780 db013d637acbe1ee5b44fb7453d24c72 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 4.0E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c25780 db013d637acbe1ee5b44fb7453d24c72 316 SUPERFAMILY SSF46785 2 83 2.49E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c25780 db013d637acbe1ee5b44fb7453d24c72 316 Pfam PF03466 LysR substrate binding domain 91 292 3.5E-32 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c25780 db013d637acbe1ee5b44fb7453d24c72 316 Gene3D G3DSA:3.40.190.10 103 288 6.8E-42 T 12-10-2018 MIM_c25780 db013d637acbe1ee5b44fb7453d24c72 316 Gene3D G3DSA:1.10.10.10 4 95 1.7E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c25780 db013d637acbe1ee5b44fb7453d24c72 316 SUPERFAMILY SSF53850 93 294 1.77E-34 T 12-10-2018 MIM_c25780 db013d637acbe1ee5b44fb7453d24c72 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c25780 db013d637acbe1ee5b44fb7453d24c72 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c25780 db013d637acbe1ee5b44fb7453d24c72 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c26090 7f8f4b313e9bf3251a7e570e70c542ef 384 Pfam PF00117 Glutamine amidotransferase class-I 203 378 6.7E-43 T 12-10-2018 IPR017926 Glutamine amidotransferase MIM_c26090 7f8f4b313e9bf3251a7e570e70c542ef 384 Gene3D G3DSA:3.40.50.880 161 383 3.3E-69 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c26090 7f8f4b313e9bf3251a7e570e70c542ef 384 SMART SM01097 14 144 3.8E-90 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MIM_c26090 7f8f4b313e9bf3251a7e570e70c542ef 384 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 16 381 7.4E-140 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MIM_c26090 7f8f4b313e9bf3251a7e570e70c542ef 384 SUPERFAMILY SSF52021 15 152 3.01E-56 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MIM_c26090 7f8f4b313e9bf3251a7e570e70c542ef 384 SUPERFAMILY SSF52317 164 381 1.08E-58 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c26090 7f8f4b313e9bf3251a7e570e70c542ef 384 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 312 323 2.5E-37 T 12-10-2018 MIM_c26090 7f8f4b313e9bf3251a7e570e70c542ef 384 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 270 286 2.5E-37 T 12-10-2018 MIM_c26090 7f8f4b313e9bf3251a7e570e70c542ef 384 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 287 304 2.5E-37 T 12-10-2018 MIM_c26090 7f8f4b313e9bf3251a7e570e70c542ef 384 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 239 253 2.5E-37 T 12-10-2018 MIM_c26090 7f8f4b313e9bf3251a7e570e70c542ef 384 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 200 214 2.5E-37 T 12-10-2018 MIM_c26090 7f8f4b313e9bf3251a7e570e70c542ef 384 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 14 384 46.342 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MIM_c26090 7f8f4b313e9bf3251a7e570e70c542ef 384 PRINTS PR00096 Glutamine amidotransferase superfamily signature 270 281 1.2E-9 T 12-10-2018 MIM_c26090 7f8f4b313e9bf3251a7e570e70c542ef 384 PRINTS PR00096 Glutamine amidotransferase superfamily signature 355 368 1.2E-9 T 12-10-2018 MIM_c26090 7f8f4b313e9bf3251a7e570e70c542ef 384 PRINTS PR00096 Glutamine amidotransferase superfamily signature 242 251 1.2E-9 T 12-10-2018 MIM_c26090 7f8f4b313e9bf3251a7e570e70c542ef 384 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 16 143 1.6E-51 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MIM_c26090 7f8f4b313e9bf3251a7e570e70c542ef 384 Gene3D G3DSA:3.50.30.20 14 160 5.6E-58 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MIM_c26980 c5b2194b29543d04451049bbe029f7d2 297 SUPERFAMILY SSF46785 6 115 6.64E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c26980 c5b2194b29543d04451049bbe029f7d2 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 6.9E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c26980 c5b2194b29543d04451049bbe029f7d2 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 6.9E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c26980 c5b2194b29543d04451049bbe029f7d2 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 6.9E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c26980 c5b2194b29543d04451049bbe029f7d2 297 Pfam PF03466 LysR substrate binding domain 91 294 8.1E-27 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c26980 c5b2194b29543d04451049bbe029f7d2 297 Gene3D G3DSA:3.40.190.10 104 291 2.7E-43 T 12-10-2018 MIM_c26980 c5b2194b29543d04451049bbe029f7d2 297 Gene3D G3DSA:1.10.10.10 7 86 1.2E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c26980 c5b2194b29543d04451049bbe029f7d2 297 Gene3D G3DSA:3.40.190.10 164 264 2.7E-43 T 12-10-2018 MIM_c26980 c5b2194b29543d04451049bbe029f7d2 297 SUPERFAMILY SSF53850 92 295 4.89E-29 T 12-10-2018 MIM_c26980 c5b2194b29543d04451049bbe029f7d2 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 66 1.3E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c04300 3ee522c15200b5f1db27319babfdbc1a 397 Gene3D G3DSA:3.10.310.10 15 386 3.4E-138 T 12-10-2018 MIM_c04300 3ee522c15200b5f1db27319babfdbc1a 397 SUPERFAMILY SSF54506 181 390 1.26E-57 T 12-10-2018 MIM_c04300 3ee522c15200b5f1db27319babfdbc1a 397 SUPERFAMILY SSF54506 10 177 3.69E-59 T 12-10-2018 MIM_c04300 3ee522c15200b5f1db27319babfdbc1a 397 Pfam PF04303 PrpF protein 14 388 1.5E-115 T 12-10-2018 IPR007400 PrpF protein MIM_c04300 3ee522c15200b5f1db27319babfdbc1a 397 Gene3D G3DSA:3.10.310.10 177 372 3.4E-138 T 12-10-2018 MIM_c41050 e276c8e9b33d2a9dd2b9fdc9b0b421d4 398 Pfam PF02515 CoA-transferase family III 11 372 9.5E-106 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 MIM_c41050 e276c8e9b33d2a9dd2b9fdc9b0b421d4 398 Gene3D G3DSA:3.40.50.10540 10 389 1.6E-108 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c41050 e276c8e9b33d2a9dd2b9fdc9b0b421d4 398 Gene3D G3DSA:3.30.1540.10 227 324 1.6E-108 T 12-10-2018 MIM_c41050 e276c8e9b33d2a9dd2b9fdc9b0b421d4 398 SUPERFAMILY SSF89796 6 395 4.58E-116 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 PRINTS PR00681 Ribosomal protein S1 signature 31 49 1.3E-81 T 12-10-2018 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 PRINTS PR00681 Ribosomal protein S1 signature 136 153 1.3E-81 T 12-10-2018 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 PRINTS PR00681 Ribosomal protein S1 signature 222 243 1.3E-81 T 12-10-2018 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 PRINTS PR00681 Ribosomal protein S1 signature 165 185 1.3E-81 T 12-10-2018 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 PRINTS PR00681 Ribosomal protein S1 signature 340 358 1.3E-81 T 12-10-2018 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 PRINTS PR00681 Ribosomal protein S1 signature 49 63 1.3E-81 T 12-10-2018 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 PRINTS PR00681 Ribosomal protein S1 signature 94 113 1.3E-81 T 12-10-2018 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 PRINTS PR00681 Ribosomal protein S1 signature 300 319 1.3E-81 T 12-10-2018 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 PRINTS PR00681 Ribosomal protein S1 signature 118 134 1.3E-81 T 12-10-2018 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 SUPERFAMILY SSF50249 265 365 5.37E-26 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 Gene3D G3DSA:2.40.50.140 16 107 1.4E-14 T 12-10-2018 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 SMART SM00316 200 270 7.3E-29 T 12-10-2018 IPR022967 RNA-binding domain, S1 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 SMART SM00316 29 97 0.45 T 12-10-2018 IPR022967 RNA-binding domain, S1 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 SMART SM00316 113 181 6.1E-9 T 12-10-2018 IPR022967 RNA-binding domain, S1 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 SMART SM00316 372 444 4.7E-21 T 12-10-2018 IPR022967 RNA-binding domain, S1 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 SMART SM00316 285 357 5.2E-24 T 12-10-2018 IPR022967 RNA-binding domain, S1 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 SMART SM00316 459 530 1.7E-17 T 12-10-2018 IPR022967 RNA-binding domain, S1 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 13 530 1.4E-202 T 12-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 Pfam PF00575 S1 RNA binding domain 29 95 2.4E-4 T 12-10-2018 IPR003029 S1 domain GO:0003676 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 Pfam PF00575 S1 RNA binding domain 200 270 4.9E-23 T 12-10-2018 IPR003029 S1 domain GO:0003676 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 Pfam PF00575 S1 RNA binding domain 286 357 2.3E-20 T 12-10-2018 IPR003029 S1 domain GO:0003676 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 Pfam PF00575 S1 RNA binding domain 460 530 1.3E-15 T 12-10-2018 IPR003029 S1 domain GO:0003676 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 Pfam PF00575 S1 RNA binding domain 372 444 1.8E-16 T 12-10-2018 IPR003029 S1 domain GO:0003676 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 Pfam PF00575 S1 RNA binding domain 113 181 3.0E-12 T 12-10-2018 IPR003029 S1 domain GO:0003676 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 SUPERFAMILY SSF50249 352 450 8.95E-23 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 SUPERFAMILY SSF50249 14 123 2.36E-17 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 SUPERFAMILY SSF50249 439 541 1.12E-20 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 Gene3D G3DSA:2.40.50.140 197 277 1.6E-28 T 12-10-2018 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 SUPERFAMILY SSF50249 199 287 1.29E-26 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 PIRSF PIRSF002111 2 544 3.8E-210 T 12-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 Gene3D G3DSA:2.40.50.140 108 191 1.0E-8 T 12-10-2018 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 Gene3D G3DSA:2.40.50.140 367 454 8.1E-24 T 12-10-2018 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 Gene3D G3DSA:2.40.50.140 278 366 1.2E-27 T 12-10-2018 MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 SUPERFAMILY SSF50249 113 195 1.48E-14 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c22790 8d217fde333b110bf4475cdf2c27e91f 570 Gene3D G3DSA:2.40.50.140 455 537 1.7E-19 T 12-10-2018 MIM_c04730 feb0c0d69480f2d61e34ae5e5aab1c27 1582 Gene3D G3DSA:3.20.20.70 821 1286 1.4E-203 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c04730 feb0c0d69480f2d61e34ae5e5aab1c27 1582 Pfam PF00310 Glutamine amidotransferases class-II 43 466 1.8E-183 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain MIM_c04730 feb0c0d69480f2d61e34ae5e5aab1c27 1582 Pfam PF01645 Conserved region in glutamate synthase 837 1236 6.0E-153 T 12-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 MIM_c04730 feb0c0d69480f2d61e34ae5e5aab1c27 1582 SUPERFAMILY SSF56235 43 469 1.85E-151 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MIM_c04730 feb0c0d69480f2d61e34ae5e5aab1c27 1582 SUPERFAMILY SSF51395 490 1272 5.7E-258 T 12-10-2018 MIM_c04730 feb0c0d69480f2d61e34ae5e5aab1c27 1582 Gene3D G3DSA:3.60.20.10 43 478 1.2E-179 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MIM_c04730 feb0c0d69480f2d61e34ae5e5aab1c27 1582 Pfam PF04898 Glutamate synthase central domain 497 776 4.8E-110 T 12-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 MIM_c04730 feb0c0d69480f2d61e34ae5e5aab1c27 1582 Gene3D G3DSA:2.160.20.60 1287 1580 6.2E-106 T 12-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 MIM_c04730 feb0c0d69480f2d61e34ae5e5aab1c27 1582 Pfam PF01493 GXGXG motif 1314 1500 1.1E-78 T 12-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 MIM_c04730 feb0c0d69480f2d61e34ae5e5aab1c27 1582 SUPERFAMILY SSF69336 1283 1570 1.44E-88 T 12-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 MIM_c04730 feb0c0d69480f2d61e34ae5e5aab1c27 1582 Gene3D G3DSA:3.20.20.70 479 820 3.0E-119 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c09960 390a29d00d58504d4f560fbd878064dc 504 SUPERFAMILY SSF52151 53 373 8.63E-33 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase MIM_c09960 390a29d00d58504d4f560fbd878064dc 504 Gene3D G3DSA:3.40.1090.10 39 142 5.2E-10 T 12-10-2018 MIM_c09960 390a29d00d58504d4f560fbd878064dc 504 Pfam PF01734 Patatin-like phospholipase 55 291 6.5E-18 T 12-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 MIM_c10240 f3557ad6ad28b32cf9c843719eeaecf5 385 Gene3D G3DSA:3.30.9.50 79 261 3.0E-67 T 12-10-2018 MIM_c10240 f3557ad6ad28b32cf9c843719eeaecf5 385 Pfam PF01494 FAD binding domain 151 312 4.3E-10 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 MIM_c10240 f3557ad6ad28b32cf9c843719eeaecf5 385 Gene3D G3DSA:3.50.50.60 7 313 3.0E-67 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c10240 f3557ad6ad28b32cf9c843719eeaecf5 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 154 169 4.4E-15 T 12-10-2018 MIM_c10240 f3557ad6ad28b32cf9c843719eeaecf5 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 287 303 4.4E-15 T 12-10-2018 MIM_c10240 f3557ad6ad28b32cf9c843719eeaecf5 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 4.4E-15 T 12-10-2018 MIM_c10240 f3557ad6ad28b32cf9c843719eeaecf5 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 272 287 4.4E-15 T 12-10-2018 MIM_c10240 f3557ad6ad28b32cf9c843719eeaecf5 385 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 286 299 - T 12-10-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 MIM_c10240 f3557ad6ad28b32cf9c843719eeaecf5 385 SUPERFAMILY SSF51905 5 375 5.18E-32 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c10240 f3557ad6ad28b32cf9c843719eeaecf5 385 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 7 380 1.2E-87 T 12-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 MIM_c08540 9960d9d612a5e0e46aca9dc271f5dd49 314 SUPERFAMILY SSF51412 1 309 4.73E-57 T 12-10-2018 MIM_c08540 9960d9d612a5e0e46aca9dc271f5dd49 314 Pfam PF03060 Nitronate monooxygenase 3 74 7.7E-16 T 12-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 MIM_c08540 9960d9d612a5e0e46aca9dc271f5dd49 314 Pfam PF03060 Nitronate monooxygenase 89 303 2.6E-38 T 12-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 MIM_c08540 9960d9d612a5e0e46aca9dc271f5dd49 314 Gene3D G3DSA:3.20.20.70 1 313 2.3E-87 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c22090 d69ea4cb34ee2320885fa5bb966cd612 231 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 3 231 5.4E-99 T 12-10-2018 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE MIM_c22090 d69ea4cb34ee2320885fa5bb966cd612 231 Gene3D G3DSA:3.40.50.300 1 225 1.6E-59 T 12-10-2018 MIM_c22090 d69ea4cb34ee2320885fa5bb966cd612 231 Pfam PF00005 ABC transporter 18 160 2.9E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c22090 d69ea4cb34ee2320885fa5bb966cd612 231 SMART SM00382 27 210 2.1E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c22090 d69ea4cb34ee2320885fa5bb966cd612 231 SUPERFAMILY SSF52540 3 220 1.18E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c05180 7c58da44003d157ba3b3364769a174df 388 Gene3D G3DSA:3.30.300.10 7 237 3.8E-176 T 12-10-2018 MIM_c05180 7c58da44003d157ba3b3364769a174df 388 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 386 7.2E-181 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MIM_c05180 7c58da44003d157ba3b3364769a174df 388 SUPERFAMILY SSF55973 115 236 6.77E-52 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MIM_c05180 7c58da44003d157ba3b3364769a174df 388 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 120 130 - T 12-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MIM_c05180 7c58da44003d157ba3b3364769a174df 388 Pfam PF02772 S-adenosylmethionine synthetase, central domain 119 235 4.4E-45 T 12-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MIM_c05180 7c58da44003d157ba3b3364769a174df 388 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 237 375 9.0E-67 T 12-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MIM_c05180 7c58da44003d157ba3b3364769a174df 388 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 6 103 4.0E-41 T 12-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MIM_c05180 7c58da44003d157ba3b3364769a174df 388 Gene3D G3DSA:3.30.300.10 13 274 3.8E-176 T 12-10-2018 MIM_c05180 7c58da44003d157ba3b3364769a174df 388 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 263 271 - T 12-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MIM_c05180 7c58da44003d157ba3b3364769a174df 388 PIRSF PIRSF000497 1 388 4.2E-169 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MIM_c05180 7c58da44003d157ba3b3364769a174df 388 SUPERFAMILY SSF55973 237 386 3.92E-66 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MIM_c05180 7c58da44003d157ba3b3364769a174df 388 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 4 387 56.523 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MIM_c05180 7c58da44003d157ba3b3364769a174df 388 SUPERFAMILY SSF55973 5 112 7.85E-46 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MIM_c05180 7c58da44003d157ba3b3364769a174df 388 Gene3D G3DSA:3.30.300.10 104 379 3.8E-176 T 12-10-2018 MIM_c23870 c3a9d5d0c30ef9b17322894ccb395681 199 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 47 78 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MIM_c23870 c3a9d5d0c30ef9b17322894ccb395681 199 TIGRFAM TIGR02939 RpoE_Sigma70: RNA polymerase sigma factor RpoE 1 191 2.6E-89 T 12-10-2018 IPR014286 RNA polymerase sigma-70 RpoE type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MIM_c23870 c3a9d5d0c30ef9b17322894ccb395681 199 SUPERFAMILY SSF88659 125 188 3.18E-18 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MIM_c23870 c3a9d5d0c30ef9b17322894ccb395681 199 Gene3D G3DSA:1.10.10.10 127 189 2.0E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c23870 c3a9d5d0c30ef9b17322894ccb395681 199 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 186 1.3E-33 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MIM_c23870 c3a9d5d0c30ef9b17322894ccb395681 199 SUPERFAMILY SSF88946 5 103 1.1E-30 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MIM_c23870 c3a9d5d0c30ef9b17322894ccb395681 199 Gene3D G3DSA:1.10.1740.10 1 122 2.3E-37 T 12-10-2018 MIM_c23870 c3a9d5d0c30ef9b17322894ccb395681 199 Pfam PF08281 Sigma-70, region 4 133 182 1.4E-18 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MIM_c23870 c3a9d5d0c30ef9b17322894ccb395681 199 Pfam PF04542 Sigma-70 region 2 25 92 1.4E-18 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MIM_c01060 04601ef899bf8d9067342d0a97aadbb8 136 SUPERFAMILY SSF117856 6 128 1.86E-16 T 12-10-2018 MIM_c01060 04601ef899bf8d9067342d0a97aadbb8 136 Pfam PF03479 Domain of unknown function (DUF296) 13 128 6.5E-14 T 12-10-2018 IPR005175 PPC domain MIM_c01060 04601ef899bf8d9067342d0a97aadbb8 136 Gene3D G3DSA:3.30.1330.80 4 135 1.3E-16 T 12-10-2018 MIM_c17270 0ffe945e4708507b834006010bca2414 407 Pfam PF07690 Major Facilitator Superfamily 25 301 8.9E-37 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c17270 0ffe945e4708507b834006010bca2414 407 ProSitePatterns PS00216 Sugar transport proteins signature 1. 276 293 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MIM_c17270 0ffe945e4708507b834006010bca2414 407 ProSitePatterns PS00217 Sugar transport proteins signature 2. 110 135 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MIM_c17270 0ffe945e4708507b834006010bca2414 407 Gene3D G3DSA:1.20.1250.20 12 407 4.7E-78 T 12-10-2018 MIM_c17270 0ffe945e4708507b834006010bca2414 407 SUPERFAMILY SSF103473 6 405 3.27E-79 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c13320 a2f3bc85ea728bf9d0af0b747c82ad53 760 Pfam PF00390 Malic enzyme, N-terminal domain 19 152 1.0E-25 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MIM_c13320 a2f3bc85ea728bf9d0af0b747c82ad53 760 SMART SM00919 164 401 3.1E-142 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MIM_c13320 a2f3bc85ea728bf9d0af0b747c82ad53 760 Gene3D G3DSA:3.40.50.10750 574 728 7.7E-96 T 12-10-2018 MIM_c13320 a2f3bc85ea728bf9d0af0b747c82ad53 760 Gene3D G3DSA:3.40.50.10950 443 754 7.7E-96 T 12-10-2018 MIM_c13320 a2f3bc85ea728bf9d0af0b747c82ad53 760 SUPERFAMILY SSF53223 11 162 7.19E-49 T 12-10-2018 MIM_c13320 a2f3bc85ea728bf9d0af0b747c82ad53 760 Pfam PF03949 Malic enzyme, NAD binding domain 166 361 5.3E-23 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MIM_c13320 a2f3bc85ea728bf9d0af0b747c82ad53 760 SUPERFAMILY SSF51735 164 440 6.57E-85 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c13320 a2f3bc85ea728bf9d0af0b747c82ad53 760 PIRSF PIRSF036684 1 760 0.0 T 12-10-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 MIM_c13320 a2f3bc85ea728bf9d0af0b747c82ad53 760 SMART SM01274 18 152 2.7E-75 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MIM_c13320 a2f3bc85ea728bf9d0af0b747c82ad53 760 Gene3D G3DSA:3.40.50.720 162 437 3.9E-82 T 12-10-2018 MIM_c13320 a2f3bc85ea728bf9d0af0b747c82ad53 760 SUPERFAMILY SSF53659 430 755 1.48E-87 T 12-10-2018 MIM_c13320 a2f3bc85ea728bf9d0af0b747c82ad53 760 Gene3D G3DSA:3.40.50.10380 1 161 1.5E-64 T 12-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 MIM_c13320 a2f3bc85ea728bf9d0af0b747c82ad53 760 Pfam PF01515 Phosphate acetyl/butaryl transferase 431 752 1.6E-94 T 12-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MIM_c19080 040d398a45a2cc5f93e5f1e40189cadf 289 Gene3D G3DSA:3.40.50.720 1 169 1.8E-46 T 12-10-2018 MIM_c19080 040d398a45a2cc5f93e5f1e40189cadf 289 SUPERFAMILY SSF48179 167 275 2.38E-32 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c19080 040d398a45a2cc5f93e5f1e40189cadf 289 SUPERFAMILY SSF51735 6 166 1.55E-31 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c19080 040d398a45a2cc5f93e5f1e40189cadf 289 PIRSF PIRSF000193 4 275 2.6E-67 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MIM_c19080 040d398a45a2cc5f93e5f1e40189cadf 289 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 7 272 6.7E-74 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MIM_c19080 040d398a45a2cc5f93e5f1e40189cadf 289 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 6 99 1.3E-13 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal MIM_c19080 040d398a45a2cc5f93e5f1e40189cadf 289 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 168 272 6.6E-34 T 12-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MIM_c19080 040d398a45a2cc5f93e5f1e40189cadf 289 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 5 272 24.946 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MIM_c19080 040d398a45a2cc5f93e5f1e40189cadf 289 Gene3D G3DSA:1.10.3730.10 170 277 3.2E-38 T 12-10-2018 MIM_c23420 85c7b21687f6b49888993bbb0cde2660 418 SUPERFAMILY SSF53383 4 402 1.24E-81 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c23420 85c7b21687f6b49888993bbb0cde2660 418 Pfam PF00266 Aminotransferase class-V 78 354 9.2E-19 T 12-10-2018 IPR000192 Aminotransferase class V domain MIM_c23420 85c7b21687f6b49888993bbb0cde2660 418 Hamap MF_01970 Kynureninase [kynU]. 1 401 33.542 T 12-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 MIM_c23420 85c7b21687f6b49888993bbb0cde2660 418 Gene3D G3DSA:3.40.640.10 41 304 6.7E-152 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c23420 85c7b21687f6b49888993bbb0cde2660 418 Gene3D G3DSA:3.90.1150.10 10 401 6.7E-152 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c23420 85c7b21687f6b49888993bbb0cde2660 418 PIRSF PIRSF038800 1 409 1.0E-140 T 12-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 MIM_c23420 85c7b21687f6b49888993bbb0cde2660 418 TIGRFAM TIGR01814 kynureninase: kynureninase 8 401 1.8E-99 T 12-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 MIM_c18400 7b61615b6059be4099cdd6da661bae33 418 SUPERFAMILY SSF52540 91 371 4.6E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c18400 7b61615b6059be4099cdd6da661bae33 418 SUPERFAMILY SSF50249 49 125 3.88E-28 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c18400 7b61615b6059be4099cdd6da661bae33 418 SMART SM00382 170 349 1.6E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c18400 7b61615b6059be4099cdd6da661bae33 418 SMART SM00357 52 118 1.3E-16 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 MIM_c18400 7b61615b6059be4099cdd6da661bae33 418 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 363 6.2E-24 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MIM_c18400 7b61615b6059be4099cdd6da661bae33 418 SMART SM00959 5 47 2.2E-16 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 MIM_c18400 7b61615b6059be4099cdd6da661bae33 418 Gene3D G3DSA:1.10.720.10 1 46 1.0E-17 T 12-10-2018 MIM_c18400 7b61615b6059be4099cdd6da661bae33 418 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 1.1E-30 T 12-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 MIM_c18400 7b61615b6059be4099cdd6da661bae33 418 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 418 238.508 T 12-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 MIM_c18400 7b61615b6059be4099cdd6da661bae33 418 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 6.4E-15 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 MIM_c18400 7b61615b6059be4099cdd6da661bae33 418 Gene3D G3DSA:3.40.50.300 130 417 2.9E-126 T 12-10-2018 MIM_c18400 7b61615b6059be4099cdd6da661bae33 418 SUPERFAMILY SSF68912 1 46 3.88E-11 T 12-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily MIM_c18400 7b61615b6059be4099cdd6da661bae33 418 Gene3D G3DSA:2.40.50.140 47 123 1.2E-32 T 12-10-2018 MIM_c18400 7b61615b6059be4099cdd6da661bae33 418 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 418 3.5E-206 T 12-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 MIM_c23280 35da68a102a176a21108f6febd152b40 326 Gene3D G3DSA:3.40.50.720 124 269 2.7E-111 T 12-10-2018 MIM_c23280 35da68a102a176a21108f6febd152b40 326 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 87 1.0E-8 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MIM_c23280 35da68a102a176a21108f6febd152b40 326 Gene3D G3DSA:3.90.180.10 16 319 2.7E-111 T 12-10-2018 MIM_c23280 35da68a102a176a21108f6febd152b40 326 SMART SM00829 12 323 3.4E-24 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MIM_c23280 35da68a102a176a21108f6febd152b40 326 SUPERFAMILY SSF51735 113 268 2.81E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c23280 35da68a102a176a21108f6febd152b40 326 SUPERFAMILY SSF50129 10 145 2.36E-32 T 12-10-2018 IPR011032 GroES-like superfamily MIM_c23280 35da68a102a176a21108f6febd152b40 326 Pfam PF00107 Zinc-binding dehydrogenase 152 259 7.3E-27 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MIM_c24310 fc6ba86354139c0c7fb510d700075ac2 437 Gene3D G3DSA:1.20.1250.20 2 415 1.7E-24 T 12-10-2018 MIM_c24310 fc6ba86354139c0c7fb510d700075ac2 437 SUPERFAMILY SSF103473 3 417 3.92E-25 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c24310 fc6ba86354139c0c7fb510d700075ac2 437 Pfam PF07690 Major Facilitator Superfamily 9 350 1.8E-17 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c32430 3bdfb3f97f7e839246a73f03b1197d97 316 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 7 314 9.7E-118 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 MIM_c32430 3bdfb3f97f7e839246a73f03b1197d97 316 SMART SM01400 6 123 1.9E-71 T 12-10-2018 MIM_c32430 3bdfb3f97f7e839246a73f03b1197d97 316 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 7 123 1.2E-45 T 12-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 MIM_c32430 3bdfb3f97f7e839246a73f03b1197d97 316 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 6 315 47.77 T 12-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 MIM_c32430 3bdfb3f97f7e839246a73f03b1197d97 316 Gene3D G3DSA:3.40.50.2020 9 303 9.8E-127 T 12-10-2018 MIM_c32430 3bdfb3f97f7e839246a73f03b1197d97 316 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 131 146 - T 12-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 MIM_c32430 3bdfb3f97f7e839246a73f03b1197d97 316 SUPERFAMILY SSF53271 71 305 1.51E-61 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like MIM_c32430 3bdfb3f97f7e839246a73f03b1197d97 316 Pfam PF14572 Phosphoribosyl synthetase-associated domain 205 314 2.0E-27 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 MIM_c32430 3bdfb3f97f7e839246a73f03b1197d97 316 Gene3D G3DSA:3.40.50.2020 150 291 9.8E-127 T 12-10-2018 MIM_c13900 faefe5354abb439a6a66bba9673ec44b 386 SUPERFAMILY SSF53822 27 383 1.08E-61 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c13900 faefe5354abb439a6a66bba9673ec44b 386 Pfam PF13458 Periplasmic binding protein 28 377 1.0E-55 T 12-10-2018 IPR028081 Leucine-binding protein domain MIM_c13900 faefe5354abb439a6a66bba9673ec44b 386 Gene3D G3DSA:3.40.50.2300 30 348 4.4E-59 T 12-10-2018 MIM_c13900 faefe5354abb439a6a66bba9673ec44b 386 Gene3D G3DSA:3.40.50.2300 150 280 4.4E-59 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:1.20.5.170 2211 2303 9.2E-9 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 SUPERFAMILY SSF101967 2290 2390 7.45E-6 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 SUPERFAMILY SSF101967 902 1004 2.09E-5 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05658 Head domain of trimeric autotransporter adhesin 227 250 1.3E-4 T 12-10-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 SUPERFAMILY SSF101967 2887 2990 2.48E-6 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.150.10.10 143 269 2.4E-16 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF13018 Extended Signal Peptide of Type V secretion system 2 24 9.2E-8 T 12-10-2018 IPR024973 ESPR domain MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 SUPERFAMILY SSF101967 3484 3590 3.53E-6 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 SUPERFAMILY SSF101967 3335 3440 1.16E-6 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 SUPERFAMILY SSF101967 3787 3890 2.48E-5 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 SUPERFAMILY SSF101967 2737 2840 2.48E-6 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:3.30.1300.30 4214 4309 1.0E-31 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 SUPERFAMILY SSF101967 2589 2690 8.24E-5 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.150.10.10 2841 2990 1.2E-17 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.150.10.10 2541 2690 3.0E-14 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.150.10.10 3291 3440 5.9E-17 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.150.10.10 2393 2540 6.3E-13 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.150.10.10 3890 4055 1.2E-8 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.150.10.10 4056 4213 1.4E-12 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.150.10.10 3141 3290 8.6E-14 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.150.10.10 385 508 1.2E-5 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.150.10.10 270 384 6.6E-26 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.150.10.10 1576 1684 5.0E-7 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.150.10.10 1685 1835 6.3E-14 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.150.10.10 3741 3889 3.5E-15 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.150.10.10 1836 1985 5.6E-13 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.150.10.10 2691 2840 1.1E-17 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.150.10.10 2991 3140 8.1E-18 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.150.10.10 3591 3740 2.2E-17 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.150.10.10 1986 2135 3.5E-10 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.150.10.10 3441 3590 1.8E-17 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1555 1585 3.7E-6 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 3565 3599 9.2E-10 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1331 1368 1.9E-7 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 358 400 8.2E-8 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 3865 3900 7.5E-7 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1960 1994 3.4E-5 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 2665 2699 2.0E-6 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1443 1481 1.5E-7 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 2815 2849 9.2E-10 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 2515 2549 5.6E-4 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 981 1021 1.8E-6 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 3265 3299 5.4E-5 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 4189 4230 3.7E-7 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 3115 3149 9.2E-10 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1100 1140 3.4E-6 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 2365 2399 8.2E-9 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 484 524 8.9E-5 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1810 1844 7.0E-6 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 2965 2999 9.2E-10 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 729 768 3.8E-6 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 3715 3749 9.2E-10 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 4033 4068 0.4 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 2110 2140 4.2E-6 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 603 642 5.0E-6 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 3415 3449 9.2E-10 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 2215 2249 3.4E-5 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1660 1694 3.4E-5 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 855 894 1.9E-5 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1219 1256 1.9E-7 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 SUPERFAMILY SSF101967 649 752 4.05E-5 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 SUPERFAMILY SSF101967 776 878 3.79E-5 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 SUPERFAMILY SSF101967 1011 1123 9.15E-6 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 SUPERFAMILY SSF101967 2016 2132 1.1E-5 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.20.25.490 1253 1307 2.5E-6 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.20.25.490 649 699 3.6E-6 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.20.25.490 523 573 3.8E-6 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.20.25.490 1139 1195 2.5E-6 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.20.25.490 901 957 2.0E-6 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.20.25.490 2137 2191 3.5E-6 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.20.25.490 1365 1414 3.4E-6 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.20.25.490 1020 1076 2.5E-6 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.20.25.490 1475 1531 8.8E-7 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:2.20.25.490 775 831 2.0E-6 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 SUPERFAMILY SSF101967 511 626 2.35E-5 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 SUPERFAMILY SSF101967 2144 2240 9.55E-5 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 SUPERFAMILY SSF101967 401 507 1.57E-6 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 SUPERFAMILY SSF101967 1259 1354 9.29E-6 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 SUPERFAMILY SSF101967 3634 3740 3.27E-6 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 SUPERFAMILY SSF101967 1481 1578 9.15E-6 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Pfam PF03895 YadA-like membrane anchor domain 4249 4309 1.1E-16 T 12-10-2018 IPR005594 YadA-like, C-terminal MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 SUPERFAMILY SSF54523 4202 4309 1.88E-21 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 SUPERFAMILY SSF101967 1140 1242 7.98E-6 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 SUPERFAMILY SSF101967 4119 4213 9.15E-5 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 SUPERFAMILY SSF101967 165 383 1.1E-24 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 SUPERFAMILY SSF101967 3037 3140 2.35E-6 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 SUPERFAMILY SSF101967 1371 1466 7.72E-6 T 12-10-2018 MIM_c22480 b05e49a33a828c36c77cc93b813e820b 4309 Gene3D G3DSA:1.20.5.170 2371 2392 1.1E-6 T 12-10-2018 MIM_c01890 28e036477c089e80fc6c7674e0574855 221 Gene3D G3DSA:2.130.10.10 9 219 1.5E-11 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MIM_c01890 28e036477c089e80fc6c7674e0574855 221 SUPERFAMILY SSF50969 28 218 8.63E-22 T 12-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like MIM_c12860 f7f8493bbd275f2571b050741fd6bb3a 279 Gene3D G3DSA:3.40.50.300 17 253 1.3E-63 T 12-10-2018 MIM_c12860 f7f8493bbd275f2571b050741fd6bb3a 279 Pfam PF00005 ABC transporter 33 180 1.6E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c12860 f7f8493bbd275f2571b050741fd6bb3a 279 SMART SM00382 41 230 1.2E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c12860 f7f8493bbd275f2571b050741fd6bb3a 279 SUPERFAMILY SSF52540 19 233 1.63E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c24860 546019730e0c0c7650a5e1c56b905cb0 226 Gene3D G3DSA:4.10.860.20 180 226 4.6E-21 T 12-10-2018 MIM_c24860 546019730e0c0c7650a5e1c56b905cb0 226 Gene3D G3DSA:2.60.120.620 1 178 9.5E-41 T 12-10-2018 MIM_c24860 546019730e0c0c7650a5e1c56b905cb0 226 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 83 176 1.8E-15 T 12-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 MIM_c24860 546019730e0c0c7650a5e1c56b905cb0 226 SMART SM00702 1 177 1.9E-13 T 12-10-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 MIM_c24860 546019730e0c0c7650a5e1c56b905cb0 226 Hamap MF_00657 PKHD-type hydroxylase YbiX [ybiX]. 1 226 43.072 T 12-10-2018 IPR023550 PKHD-type hydroxylase GO:0016706|GO:0055114 MIM_c27650 aeeca65a14ac4f89c889b0f32dbbebc9 139 Gene3D G3DSA:3.30.160.250 1 96 1.3E-16 T 12-10-2018 MIM_c27650 aeeca65a14ac4f89c889b0f32dbbebc9 139 SUPERFAMILY SSF143100 1 65 6.02E-15 T 12-10-2018 IPR035069 TTHA1013/TTHA0281-like MIM_c27650 aeeca65a14ac4f89c889b0f32dbbebc9 139 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 4 123 2.1E-11 T 12-10-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system MIM_c33450 08cdff724a3ad98cba73881f74ab5f15 93 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 7 85 2.9E-13 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MIM_c33450 08cdff724a3ad98cba73881f74ab5f15 93 SUPERFAMILY SSF54292 4 91 5.64E-21 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MIM_c33450 08cdff724a3ad98cba73881f74ab5f15 93 Gene3D G3DSA:3.10.20.30 1 93 6.1E-22 T 12-10-2018 IPR012675 Beta-grasp domain superfamily MIM_c33450 08cdff724a3ad98cba73881f74ab5f15 93 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MIM_c41150 46507e8fd2cfd32375ecedf2e83e97b8 358 SUPERFAMILY SSF51735 120 327 6.62E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c41150 46507e8fd2cfd32375ecedf2e83e97b8 358 Gene3D G3DSA:3.40.50.720 72 355 8.0E-71 T 12-10-2018 MIM_c41150 46507e8fd2cfd32375ecedf2e83e97b8 358 Gene3D G3DSA:3.40.50.720 118 332 8.0E-71 T 12-10-2018 MIM_c41150 46507e8fd2cfd32375ecedf2e83e97b8 358 SUPERFAMILY SSF52283 70 148 1.43E-7 T 12-10-2018 MIM_c41150 46507e8fd2cfd32375ecedf2e83e97b8 358 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 126 326 1.9E-41 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MIM_c40230 0e0c2ce2fc250810da45680c6e5d0e42 187 SMART SM00530 13 68 1.3E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c40230 0e0c2ce2fc250810da45680c6e5d0e42 187 SUPERFAMILY SSF51182 61 182 1.56E-15 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c40230 0e0c2ce2fc250810da45680c6e5d0e42 187 Pfam PF01381 Helix-turn-helix 14 67 6.5E-12 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c40230 0e0c2ce2fc250810da45680c6e5d0e42 187 SUPERFAMILY SSF47413 7 72 1.55E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c40230 0e0c2ce2fc250810da45680c6e5d0e42 187 Gene3D G3DSA:1.10.260.40 1 78 1.9E-18 T 12-10-2018 MIM_c40230 0e0c2ce2fc250810da45680c6e5d0e42 187 Gene3D G3DSA:2.60.120.10 81 184 2.0E-6 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c28770 bc8ff1d0d1e0032850e1aeaae182109b 808 Gene3D G3DSA:2.40.50.230 359 461 1.5E-42 T 12-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily MIM_c28770 bc8ff1d0d1e0032850e1aeaae182109b 808 SUPERFAMILY SSF69279 193 367 9.18E-36 T 12-10-2018 MIM_c28770 bc8ff1d0d1e0032850e1aeaae182109b 808 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 20 525 1.7E-176 T 12-10-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset MIM_c28770 bc8ff1d0d1e0032850e1aeaae182109b 808 SUPERFAMILY SSF69349 446 657 4.39E-27 T 12-10-2018 MIM_c28770 bc8ff1d0d1e0032850e1aeaae182109b 808 Pfam PF05954 Phage late control gene D protein (GPD) 32 331 5.5E-91 T 12-10-2018 MIM_c28770 bc8ff1d0d1e0032850e1aeaae182109b 808 SUPERFAMILY SSF69279 19 189 2.98E-55 T 12-10-2018 MIM_c28770 bc8ff1d0d1e0032850e1aeaae182109b 808 Gene3D G3DSA:3.55.50.10 103 193 2.4E-108 T 12-10-2018 MIM_c28770 bc8ff1d0d1e0032850e1aeaae182109b 808 SUPERFAMILY SSF69255 369 456 4.18E-32 T 12-10-2018 MIM_c28770 bc8ff1d0d1e0032850e1aeaae182109b 808 Gene3D G3DSA:3.30.1920.30 229 291 2.4E-108 T 12-10-2018 MIM_c28770 bc8ff1d0d1e0032850e1aeaae182109b 808 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 26 507 7.3E-140 T 12-10-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein MIM_c28770 bc8ff1d0d1e0032850e1aeaae182109b 808 Gene3D G3DSA:2.30.110.50 17 334 2.4E-108 T 12-10-2018 MIM_c07620 f818fe967731b6968df4428f14491572 687 Gene3D G3DSA:3.40.50.300 9 268 5.9E-86 T 12-10-2018 MIM_c07620 f818fe967731b6968df4428f14491572 687 Gene3D G3DSA:1.10.486.10 379 553 1.3E-103 T 12-10-2018 MIM_c07620 f818fe967731b6968df4428f14491572 687 Gene3D G3DSA:1.10.10.160 113 183 5.9E-86 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily MIM_c07620 f818fe967731b6968df4428f14491572 687 Pfam PF00580 UvrD/REP helicase N-terminal domain 8 267 7.6E-68 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 MIM_c07620 f818fe967731b6968df4428f14491572 687 Hamap MF_01920 ATP-dependent DNA helicase Rep [rep]. 6 684 36.38 T 12-10-2018 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 MIM_c07620 f818fe967731b6968df4428f14491572 687 SUPERFAMILY SSF52540 2 654 1.05E-151 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c07620 f818fe967731b6968df4428f14491572 687 Pfam PF13361 UvrD-like helicase C-terminal domain 273 634 4.5E-60 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MIM_c07620 f818fe967731b6968df4428f14491572 687 Gene3D G3DSA:3.40.50.300 276 653 1.3E-103 T 12-10-2018 MIM_c12350 dfe0525456bff372382e776e4d558d89 291 ProSitePatterns PS00211 ABC transporters family signature. 184 198 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c12350 dfe0525456bff372382e776e4d558d89 291 TIGRFAM TIGR03005 ectoine_ehuA: ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA 39 288 1.0E-122 T 12-10-2018 IPR014343 Ectoine/hydroxyectoine ABC transporter, ATP-binding protein MIM_c12350 dfe0525456bff372382e776e4d558d89 291 SUPERFAMILY SSF52540 38 283 5.44E-79 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c12350 dfe0525456bff372382e776e4d558d89 291 Gene3D G3DSA:3.40.50.300 35 290 9.6E-80 T 12-10-2018 MIM_c12350 dfe0525456bff372382e776e4d558d89 291 Pfam PF00005 ABC transporter 54 212 1.2E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c12350 dfe0525456bff372382e776e4d558d89 291 PIRSF PIRSF039085 35 289 3.7E-109 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MIM_c12350 dfe0525456bff372382e776e4d558d89 291 SMART SM00382 63 261 1.8E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c21310 e3bffc061565b8ee1e3a3760147a1a49 260 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 248 6.1E-19 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase MIM_c21310 e3bffc061565b8ee1e3a3760147a1a49 260 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 255 6.5E-76 T 12-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 MIM_c21310 e3bffc061565b8ee1e3a3760147a1a49 260 SUPERFAMILY SSF56219 1 256 7.59E-78 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MIM_c21310 e3bffc061565b8ee1e3a3760147a1a49 260 Gene3D G3DSA:3.60.10.10 1 256 2.0E-70 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MIM_c21310 e3bffc061565b8ee1e3a3760147a1a49 260 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 255 2.2E-78 T 12-10-2018 MIM_c20760 93532e95647fb63cd5ed55e5f0d6e4b1 235 Gene3D G3DSA:3.40.50.300 3 235 3.5E-56 T 12-10-2018 MIM_c20760 93532e95647fb63cd5ed55e5f0d6e4b1 235 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c20760 93532e95647fb63cd5ed55e5f0d6e4b1 235 SUPERFAMILY SSF52540 6 233 3.84E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c20760 93532e95647fb63cd5ed55e5f0d6e4b1 235 Pfam PF00005 ABC transporter 23 163 6.8E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c20760 93532e95647fb63cd5ed55e5f0d6e4b1 235 SMART SM00382 32 214 3.0E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c22260 7d925dd3a821d5259e801db51075b20e 69 PIRSF PIRSF002599 1 69 1.2E-22 T 12-10-2018 IPR012156 Cold shock, CspA GO:0003676 MIM_c22260 7d925dd3a821d5259e801db51075b20e 69 SMART SM00357 5 69 1.3E-24 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 MIM_c22260 7d925dd3a821d5259e801db51075b20e 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 17 36 - T 12-10-2018 IPR019844 Cold-shock conserved site MIM_c22260 7d925dd3a821d5259e801db51075b20e 69 Pfam PF00313 'Cold-shock' DNA-binding domain 5 67 2.6E-27 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MIM_c22260 7d925dd3a821d5259e801db51075b20e 69 PRINTS PR00050 Cold shock protein signature 27 36 4.9E-15 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MIM_c22260 7d925dd3a821d5259e801db51075b20e 69 PRINTS PR00050 Cold shock protein signature 6 21 4.9E-15 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MIM_c22260 7d925dd3a821d5259e801db51075b20e 69 PRINTS PR00050 Cold shock protein signature 42 60 4.9E-15 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MIM_c22260 7d925dd3a821d5259e801db51075b20e 69 SUPERFAMILY SSF50249 4 67 7.5E-23 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c22260 7d925dd3a821d5259e801db51075b20e 69 Gene3D G3DSA:2.40.50.140 4 68 9.9E-28 T 12-10-2018 MIM_c06270 22896246bd415263c26011174961c377 1105 SUPERFAMILY SSF52096 818 1085 6.39E-57 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c06270 22896246bd415263c26011174961c377 1105 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 526 543 - T 12-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MIM_c06270 22896246bd415263c26011174961c377 1105 Gene3D G3DSA:3.30.1490.20 129 200 1.3E-19 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MIM_c06270 22896246bd415263c26011174961c377 1105 SUPERFAMILY SSF51246 336 457 2.41E-26 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MIM_c06270 22896246bd415263c26011174961c377 1105 SMART SM00878 342 452 5.1E-34 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MIM_c06270 22896246bd415263c26011174961c377 1105 SUPERFAMILY SSF52440 1 109 6.69E-40 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MIM_c06270 22896246bd415263c26011174961c377 1105 Gene3D G3DSA:3.90.226.10 847 1085 2.3E-66 T 12-10-2018 MIM_c06270 22896246bd415263c26011174961c377 1105 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 113 325 7.3E-56 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MIM_c06270 22896246bd415263c26011174961c377 1105 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 288 295 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MIM_c06270 22896246bd415263c26011174961c377 1105 Pfam PF01039 Carboxyl transferase domain 616 1083 5.8E-71 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 MIM_c06270 22896246bd415263c26011174961c377 1105 Gene3D G3DSA:3.40.50.20 1 128 1.7E-46 T 12-10-2018 MIM_c06270 22896246bd415263c26011174961c377 1105 Gene3D G3DSA:3.30.470.20 201 466 1.5E-89 T 12-10-2018 MIM_c06270 22896246bd415263c26011174961c377 1105 Gene3D G3DSA:2.40.50.100 505 572 1.6E-18 T 12-10-2018 MIM_c06270 22896246bd415263c26011174961c377 1105 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 107 2.3E-39 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MIM_c06270 22896246bd415263c26011174961c377 1105 SUPERFAMILY SSF56059 81 332 7.6E-51 T 12-10-2018 MIM_c06270 22896246bd415263c26011174961c377 1105 Pfam PF02785 Biotin carboxylase C-terminal domain 342 452 1.7E-26 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MIM_c06270 22896246bd415263c26011174961c377 1105 Gene3D G3DSA:3.90.226.10 586 846 3.1E-68 T 12-10-2018 MIM_c06270 22896246bd415263c26011174961c377 1105 Pfam PF00364 Biotin-requiring enzyme 509 569 6.4E-14 T 12-10-2018 IPR000089 Biotin/lipoyl attachment MIM_c06270 22896246bd415263c26011174961c377 1105 SUPERFAMILY SSF51230 495 570 6.41E-18 T 12-10-2018 IPR011053 Single hybrid motif MIM_c06270 22896246bd415263c26011174961c377 1105 SUPERFAMILY SSF52096 593 848 6.14E-50 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c03380 fc12f8b78fd8bc8d0b21b92be0749c26 798 SUPERFAMILY SSF56645 411 640 3.8E-67 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c03380 fc12f8b78fd8bc8d0b21b92be0749c26 798 Gene3D G3DSA:1.10.540.10 3 118 9.3E-17 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c03380 fc12f8b78fd8bc8d0b21b92be0749c26 798 SUPERFAMILY SSF47203 629 793 1.21E-8 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c03380 fc12f8b78fd8bc8d0b21b92be0749c26 798 SUPERFAMILY SSF47203 230 368 1.61E-29 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c03380 fc12f8b78fd8bc8d0b21b92be0749c26 798 Gene3D G3DSA:1.20.140.10 634 798 2.7E-19 T 12-10-2018 MIM_c03380 fc12f8b78fd8bc8d0b21b92be0749c26 798 Gene3D G3DSA:1.20.140.10 224 362 5.8E-27 T 12-10-2018 MIM_c03380 fc12f8b78fd8bc8d0b21b92be0749c26 798 Gene3D G3DSA:1.10.540.10 409 518 5.6E-24 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c03380 fc12f8b78fd8bc8d0b21b92be0749c26 798 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 411 519 5.6E-18 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c03380 fc12f8b78fd8bc8d0b21b92be0749c26 798 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 94 3.0E-8 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c03380 fc12f8b78fd8bc8d0b21b92be0749c26 798 Gene3D G3DSA:2.40.110.10 523 633 2.1E-34 T 12-10-2018 MIM_c03380 fc12f8b78fd8bc8d0b21b92be0749c26 798 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 629 792 3.4E-8 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MIM_c03380 fc12f8b78fd8bc8d0b21b92be0749c26 798 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 347 2.4E-22 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MIM_c03380 fc12f8b78fd8bc8d0b21b92be0749c26 798 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 524 617 5.8E-19 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MIM_c03380 fc12f8b78fd8bc8d0b21b92be0749c26 798 Gene3D G3DSA:2.40.110.10 129 223 4.1E-5 T 12-10-2018 MIM_c03380 fc12f8b78fd8bc8d0b21b92be0749c26 798 SUPERFAMILY SSF56645 8 215 2.36E-18 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c17890 5ab5e9217a82c6043d22efc30e85d314 435 Pfam PF13393 Histidyl-tRNA synthetase 15 318 2.2E-45 T 12-10-2018 MIM_c17890 5ab5e9217a82c6043d22efc30e85d314 435 SUPERFAMILY SSF55681 12 324 3.58E-95 T 12-10-2018 MIM_c17890 5ab5e9217a82c6043d22efc30e85d314 435 Gene3D G3DSA:3.30.930.10 7 329 1.6E-112 T 12-10-2018 MIM_c17890 5ab5e9217a82c6043d22efc30e85d314 435 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 12 411 1.8E-146 T 12-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 MIM_c17890 5ab5e9217a82c6043d22efc30e85d314 435 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 8 430 30.863 T 12-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 MIM_c17890 5ab5e9217a82c6043d22efc30e85d314 435 PIRSF PIRSF001549 6 432 8.0E-112 T 12-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 MIM_c17890 5ab5e9217a82c6043d22efc30e85d314 435 Pfam PF03129 Anticodon binding domain 346 428 4.2E-7 T 12-10-2018 IPR004154 Anticodon-binding MIM_c17890 5ab5e9217a82c6043d22efc30e85d314 435 SUPERFAMILY SSF52954 332 430 1.39E-16 T 12-10-2018 MIM_c17890 5ab5e9217a82c6043d22efc30e85d314 435 Gene3D G3DSA:3.40.50.800 330 429 1.6E-19 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily MIM_c38350 950aa4e77160e233a019b451e79f6c51 713 SUPERFAMILY SSF56059 491 705 4.99E-40 T 12-10-2018 MIM_c38350 950aa4e77160e233a019b451e79f6c51 713 SUPERFAMILY SSF52210 157 304 3.27E-38 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c38350 950aa4e77160e233a019b451e79f6c51 713 Gene3D G3DSA:3.40.50.261 149 306 4.2E-49 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c38350 950aa4e77160e233a019b451e79f6c51 713 Gene3D G3DSA:3.30.1490.20 509 586 2.2E-77 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MIM_c38350 950aa4e77160e233a019b451e79f6c51 713 SUPERFAMILY SSF51735 13 141 3.5E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c38350 950aa4e77160e233a019b451e79f6c51 713 Pfam PF13549 ATP-grasp domain 491 702 8.0E-66 T 12-10-2018 MIM_c38350 950aa4e77160e233a019b451e79f6c51 713 SUPERFAMILY SSF52210 313 468 1.14E-21 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c38350 950aa4e77160e233a019b451e79f6c51 713 Gene3D G3DSA:3.40.50.261 311 472 8.6E-26 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c38350 950aa4e77160e233a019b451e79f6c51 713 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 166 303 3.5E-47 T 12-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain MIM_c38350 950aa4e77160e233a019b451e79f6c51 713 SMART SM00881 16 111 2.9E-36 T 12-10-2018 IPR003781 CoA-binding GO:0048037 MIM_c38350 950aa4e77160e233a019b451e79f6c51 713 Gene3D G3DSA:3.40.50.720 11 140 6.6E-42 T 12-10-2018 MIM_c38350 950aa4e77160e233a019b451e79f6c51 713 Pfam PF13380 CoA binding domain 22 144 3.4E-23 T 12-10-2018 IPR003781 CoA-binding GO:0048037 MIM_c38350 950aa4e77160e233a019b451e79f6c51 713 Gene3D G3DSA:3.30.470.20 492 702 2.2E-77 T 12-10-2018 MIM_c07510 08aedf204254973aeef8720c415ae71a 303 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 303 4.6E-98 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07510 08aedf204254973aeef8720c415ae71a 303 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 289 302 - T 12-10-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07510 08aedf204254973aeef8720c415ae71a 303 PRINTS PR00126 ATP synthase gamma subunit signature 250 269 1.8E-33 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07510 08aedf204254973aeef8720c415ae71a 303 PRINTS PR00126 ATP synthase gamma subunit signature 281 302 1.8E-33 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07510 08aedf204254973aeef8720c415ae71a 303 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 1.8E-33 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07510 08aedf204254973aeef8720c415ae71a 303 PRINTS PR00126 ATP synthase gamma subunit signature 167 184 1.8E-33 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07510 08aedf204254973aeef8720c415ae71a 303 Gene3D G3DSA:1.10.287.80 6 299 7.4E-101 T 12-10-2018 MIM_c07510 08aedf204254973aeef8720c415ae71a 303 Pfam PF00231 ATP synthase 4 302 1.6E-90 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07510 08aedf204254973aeef8720c415ae71a 303 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 303 34.854 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07510 08aedf204254973aeef8720c415ae71a 303 SUPERFAMILY SSF52943 3 303 7.85E-90 T 12-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07510 08aedf204254973aeef8720c415ae71a 303 Gene3D G3DSA:3.40.1380.10 61 222 7.4E-101 T 12-10-2018 MIM_c16160 195dafd07b7d89d4b34b781cbeb8526f 676 SUPERFAMILY SSF102588 29 289 3.4E-13 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 MIM_c16160 195dafd07b7d89d4b34b781cbeb8526f 676 SUPERFAMILY SSF89372 238 419 2.22E-6 T 12-10-2018 MIM_c16160 195dafd07b7d89d4b34b781cbeb8526f 676 SUPERFAMILY SSF89372 447 619 5.62E-7 T 12-10-2018 MIM_c16160 195dafd07b7d89d4b34b781cbeb8526f 676 Gene3D G3DSA:3.40.50.10320 25 260 4.3E-9 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 MIM_c16160 195dafd07b7d89d4b34b781cbeb8526f 676 Pfam PF02585 GlcNAc-PI de-N-acetylase 29 217 1.3E-12 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 MIM_c11580 81180dfdb86484eb1f8f9b76a0694648 296 ProSitePatterns PS01335 Methylglyoxal synthase active site. 223 231 - T 12-10-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 MIM_c11580 81180dfdb86484eb1f8f9b76a0694648 296 Gene3D G3DSA:3.40.50.1380 16 144 4.8E-8 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily MIM_c11580 81180dfdb86484eb1f8f9b76a0694648 296 SUPERFAMILY SSF52335 17 141 5.04E-17 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily MIM_c11580 81180dfdb86484eb1f8f9b76a0694648 296 SUPERFAMILY SSF52335 158 292 5.26E-30 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily MIM_c11580 81180dfdb86484eb1f8f9b76a0694648 296 Gene3D G3DSA:3.40.50.1380 159 295 7.0E-40 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily MIM_c22970 319a14b7a4e3c08e0e5ae3032381a793 408 Pfam PF01471 Putative peptidoglycan binding domain 352 407 2.9E-11 T 12-10-2018 IPR002477 Peptidoglycan binding-like MIM_c22970 319a14b7a4e3c08e0e5ae3032381a793 408 Gene3D G3DSA:1.10.8.350 48 212 2.1E-83 T 12-10-2018 MIM_c22970 319a14b7a4e3c08e0e5ae3032381a793 408 Gene3D G3DSA:1.10.101.10 343 408 3.2E-10 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 MIM_c22970 319a14b7a4e3c08e0e5ae3032381a793 408 SUPERFAMILY SSF53955 21 338 2.53E-96 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily MIM_c22970 319a14b7a4e3c08e0e5ae3032381a793 408 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 36 334 1.4E-110 T 12-10-2018 IPR011970 Lytic murein transglycosylase MIM_c22970 319a14b7a4e3c08e0e5ae3032381a793 408 Pfam PF13406 Transglycosylase SLT domain 37 331 4.5E-105 T 12-10-2018 IPR031304 Transglycosylase SLT domain 2 MIM_c22970 319a14b7a4e3c08e0e5ae3032381a793 408 Gene3D G3DSA:1.10.530.10 79 330 2.1E-83 T 12-10-2018 MIM_c22970 319a14b7a4e3c08e0e5ae3032381a793 408 SUPERFAMILY SSF47090 338 407 2.59E-16 T 12-10-2018 IPR036365 PGBD-like superfamily MIM_c37330 1122bc4cbfd0f305d59cb79822cb8ba9 110 Gene3D G3DSA:1.10.1660.10 14 105 2.0E-21 T 12-10-2018 MIM_c37330 1122bc4cbfd0f305d59cb79822cb8ba9 110 Pfam PF13591 MerR HTH family regulatory protein 20 100 6.3E-15 T 12-10-2018 MIM_c29760 0dd5bcee4b482713f27f027279259b09 181 Pfam PF07291 Methylamine utilisation protein MauE 1 178 2.0E-51 T 12-10-2018 IPR009908 Methylamine utilisation protein, MauE GO:0016021|GO:0030416 MIM_c33990 e0a9cb0ac71eeae88dabb635d3f1c113 700 Pfam PF05954 Phage late control gene D protein (GPD) 38 340 2.9E-83 T 12-10-2018 MIM_c33990 e0a9cb0ac71eeae88dabb635d3f1c113 700 SUPERFAMILY SSF69255 379 467 7.59E-33 T 12-10-2018 MIM_c33990 e0a9cb0ac71eeae88dabb635d3f1c113 700 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 34 521 1.4E-134 T 12-10-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein MIM_c33990 e0a9cb0ac71eeae88dabb635d3f1c113 700 Gene3D G3DSA:2.40.50.230 370 471 4.7E-42 T 12-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily MIM_c33990 e0a9cb0ac71eeae88dabb635d3f1c113 700 SUPERFAMILY SSF69279 197 379 5.44E-32 T 12-10-2018 MIM_c33990 e0a9cb0ac71eeae88dabb635d3f1c113 700 SUPERFAMILY SSF69349 457 655 1.26E-44 T 12-10-2018 MIM_c33990 e0a9cb0ac71eeae88dabb635d3f1c113 700 Gene3D G3DSA:3.55.50.10 108 198 2.8E-99 T 12-10-2018 MIM_c33990 e0a9cb0ac71eeae88dabb635d3f1c113 700 SUPERFAMILY SSF69279 27 193 9.78E-49 T 12-10-2018 MIM_c33990 e0a9cb0ac71eeae88dabb635d3f1c113 700 Gene3D G3DSA:2.30.110.50 30 342 2.8E-99 T 12-10-2018 MIM_c33990 e0a9cb0ac71eeae88dabb635d3f1c113 700 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 25 538 2.0E-174 T 12-10-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset MIM_c33990 e0a9cb0ac71eeae88dabb635d3f1c113 700 Gene3D G3DSA:3.30.1920.30 234 296 2.8E-99 T 12-10-2018 MIM_c28580 2ca5b8374386542277258b80a4671ed1 466 Pfam PF07690 Major Facilitator Superfamily 36 400 2.7E-32 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c28580 2ca5b8374386542277258b80a4671ed1 466 Gene3D G3DSA:1.20.1250.20 17 447 1.5E-41 T 12-10-2018 MIM_c28580 2ca5b8374386542277258b80a4671ed1 466 SUPERFAMILY SSF103473 20 447 2.09E-47 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c15690 31ab842fe2a6f7754ab1c8016dbd0347 378 SUPERFAMILY SSF56300 1 317 2.25E-60 T 12-10-2018 MIM_c15690 31ab842fe2a6f7754ab1c8016dbd0347 378 Pfam PF00149 Calcineurin-like phosphoesterase 1 215 1.7E-13 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MIM_c15690 31ab842fe2a6f7754ab1c8016dbd0347 378 Gene3D G3DSA:3.60.21.10 1 263 1.2E-84 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like MIM_c15690 31ab842fe2a6f7754ab1c8016dbd0347 378 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 264 352 1.6E-11 T 12-10-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain MIM_c15690 31ab842fe2a6f7754ab1c8016dbd0347 378 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 243 1.0E-55 T 12-10-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 MIM_c02830 65472bb7a147d7642b4ea70d2323e302 310 Gene3D G3DSA:1.10.3720.10 84 297 9.1E-23 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c02830 65472bb7a147d7642b4ea70d2323e302 310 SUPERFAMILY SSF161098 89 286 3.49E-20 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c02830 65472bb7a147d7642b4ea70d2323e302 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 302 4.8E-38 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c38460 2dc863ed31ff00de0b1f59c807725f46 698 Pfam PF00122 E1-E2 ATPase 117 303 2.7E-29 T 12-10-2018 MIM_c38460 2dc863ed31ff00de0b1f59c807725f46 698 Gene3D G3DSA:2.70.150.20 116 226 3.3E-23 T 12-10-2018 MIM_c38460 2dc863ed31ff00de0b1f59c807725f46 698 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 557 569 4.1E-24 T 12-10-2018 MIM_c38460 2dc863ed31ff00de0b1f59c807725f46 698 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 534 553 4.1E-24 T 12-10-2018 MIM_c38460 2dc863ed31ff00de0b1f59c807725f46 698 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 325 339 4.1E-24 T 12-10-2018 MIM_c38460 2dc863ed31ff00de0b1f59c807725f46 698 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 168 182 4.1E-24 T 12-10-2018 MIM_c38460 2dc863ed31ff00de0b1f59c807725f46 698 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 481 491 4.1E-24 T 12-10-2018 MIM_c38460 2dc863ed31ff00de0b1f59c807725f46 698 Gene3D G3DSA:3.40.1110.10 337 468 3.8E-45 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MIM_c38460 2dc863ed31ff00de0b1f59c807725f46 698 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 31 695 0.0 T 12-10-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 MIM_c38460 2dc863ed31ff00de0b1f59c807725f46 698 Pfam PF00702 haloacid dehalogenase-like hydrolase 321 548 3.3E-30 T 12-10-2018 MIM_c38460 2dc863ed31ff00de0b1f59c807725f46 698 SUPERFAMILY SSF81665 43 636 4.97E-14 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 MIM_c38460 2dc863ed31ff00de0b1f59c807725f46 698 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 393 616 1.3E-42 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MIM_c38460 2dc863ed31ff00de0b1f59c807725f46 698 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 86 363 1.6E-29 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MIM_c38460 2dc863ed31ff00de0b1f59c807725f46 698 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 327 333 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MIM_c38460 2dc863ed31ff00de0b1f59c807725f46 698 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 22 698 39.181 T 12-10-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 MIM_c38460 2dc863ed31ff00de0b1f59c807725f46 698 SUPERFAMILY SSF81653 129 221 9.02E-17 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 MIM_c38460 2dc863ed31ff00de0b1f59c807725f46 698 SUPERFAMILY SSF56784 313 577 2.62E-37 T 12-10-2018 IPR036412 HAD-like superfamily MIM_c02110 2467dd95aace33a5bf5ff48a830e6cac 269 Gene3D G3DSA:3.40.190.10 118 225 5.2E-28 T 12-10-2018 MIM_c02110 2467dd95aace33a5bf5ff48a830e6cac 269 SUPERFAMILY SSF53850 35 264 2.68E-38 T 12-10-2018 MIM_c02110 2467dd95aace33a5bf5ff48a830e6cac 269 Gene3D G3DSA:3.40.190.10 37 261 5.2E-28 T 12-10-2018 MIM_c02110 2467dd95aace33a5bf5ff48a830e6cac 269 Pfam PF13531 Bacterial extracellular solute-binding protein 36 262 8.2E-30 T 12-10-2018 MIM_c25800 42a1f9c6fbdd8f84edbf832976813074 822 Gene3D G3DSA:1.10.274.90 194 339 5.2E-46 T 12-10-2018 MIM_c25800 42a1f9c6fbdd8f84edbf832976813074 822 Pfam PF06276 Ferric iron reductase FhuF-like transporter 622 778 3.1E-35 T 12-10-2018 IPR022770 Ferric iron reductase FhuF domain MIM_c25800 42a1f9c6fbdd8f84edbf832976813074 822 SUPERFAMILY SSF55729 12 180 1.78E-40 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c25800 42a1f9c6fbdd8f84edbf832976813074 822 Pfam PF13523 Acetyltransferase (GNAT) domain 24 166 2.1E-41 T 12-10-2018 MIM_c25800 42a1f9c6fbdd8f84edbf832976813074 822 SMART SM01006 20 67 3.5E-5 T 12-10-2018 IPR019432 Siderophore biosynthesis protein, conserved domain MIM_c25800 42a1f9c6fbdd8f84edbf832976813074 822 Gene3D G3DSA:3.40.630.30 5 183 1.1E-45 T 12-10-2018 MIM_c25800 42a1f9c6fbdd8f84edbf832976813074 822 Gene3D G3DSA:1.10.510.40 589 797 3.5E-68 T 12-10-2018 MIM_c25800 42a1f9c6fbdd8f84edbf832976813074 822 Pfam PF04183 IucA / IucC family 350 600 5.0E-74 T 12-10-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0019290 MIM_c00540 823e8e75f04199b5d4764c22815520d8 402 Gene3D G3DSA:3.20.20.120 134 391 3.4E-61 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MIM_c00540 823e8e75f04199b5d4764c22815520d8 402 SUPERFAMILY SSF51604 124 387 1.57E-50 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MIM_c00540 823e8e75f04199b5d4764c22815520d8 402 Pfam PF13378 Enolase C-terminal domain-like 163 385 2.6E-37 T 12-10-2018 IPR029065 Enolase C-terminal domain-like MIM_c00540 823e8e75f04199b5d4764c22815520d8 402 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 48 136 2.4E-11 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain MIM_c00540 823e8e75f04199b5d4764c22815520d8 402 SMART SM00922 160 261 3.2E-8 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MIM_c00540 823e8e75f04199b5d4764c22815520d8 402 Gene3D G3DSA:3.30.390.10 12 133 4.2E-19 T 12-10-2018 IPR029017 Enolase-like, N-terminal MIM_c00540 823e8e75f04199b5d4764c22815520d8 402 SUPERFAMILY SSF54826 13 140 3.54E-19 T 12-10-2018 MIM_c39950 2d7179d175d98df3caa52a935ef86e1e 501 Gene3D G3DSA:3.40.309.10 257 451 1.4E-142 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MIM_c39950 2d7179d175d98df3caa52a935ef86e1e 501 Pfam PF00171 Aldehyde dehydrogenase family 21 479 1.3E-131 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c39950 2d7179d175d98df3caa52a935ef86e1e 501 Gene3D G3DSA:3.40.605.10 23 476 1.4E-142 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c39950 2d7179d175d98df3caa52a935ef86e1e 501 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 253 260 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MIM_c39950 2d7179d175d98df3caa52a935ef86e1e 501 SUPERFAMILY SSF53720 18 487 1.96E-134 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c28430 866109efc39270950aa25e461fc08a2a 506 SUPERFAMILY SSF103473 8 372 4.58E-47 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c28430 866109efc39270950aa25e461fc08a2a 506 Gene3D G3DSA:1.20.1250.20 4 182 1.8E-17 T 12-10-2018 MIM_c28430 866109efc39270950aa25e461fc08a2a 506 Pfam PF07690 Major Facilitator Superfamily 11 341 1.6E-26 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c28430 866109efc39270950aa25e461fc08a2a 506 Gene3D G3DSA:1.20.1250.20 199 378 2.3E-21 T 12-10-2018 MIM_c24370 a6a5b6249271c7c21f5842c056cc2148 172 SUPERFAMILY SSF69118 4 170 5.9E-39 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c24370 a6a5b6249271c7c21f5842c056cc2148 172 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 110 158 2.7E-9 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c24370 a6a5b6249271c7c21f5842c056cc2148 172 Gene3D G3DSA:1.20.1290.10 3 172 8.7E-51 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c24370 a6a5b6249271c7c21f5842c056cc2148 172 Pfam PF02627 Carboxymuconolactone decarboxylase family 101 170 3.9E-11 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c24370 a6a5b6249271c7c21f5842c056cc2148 172 Hamap MF_01676 Alkyl hydroperoxide reductase AhpD [ahpD]. 1 172 67.541 T 12-10-2018 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c40470 e466f448f59bd03209e4b7a358543e1d 397 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 150 166 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site MIM_c40470 e466f448f59bd03209e4b7a358543e1d 397 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 71 233 3.2E-22 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MIM_c40470 e466f448f59bd03209e4b7a358543e1d 397 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 240 331 2.9E-21 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MIM_c40470 e466f448f59bd03209e4b7a358543e1d 397 SUPERFAMILY SSF53901 67 389 5.11E-44 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c40470 e466f448f59bd03209e4b7a358543e1d 397 Gene3D G3DSA:3.40.47.10 52 242 1.4E-34 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c40470 e466f448f59bd03209e4b7a358543e1d 397 Gene3D G3DSA:3.40.47.10 243 393 2.4E-36 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c40470 e466f448f59bd03209e4b7a358543e1d 397 SMART SM00825 Beta-ketoacyl synthase 66 397 9.1E-7 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MIM_c32810 8018ea27e11b84e84804a2526768cbe3 146 Pfam PF01047 MarR family 36 93 4.4E-16 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c32810 8018ea27e11b84e84804a2526768cbe3 146 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MIM_c32810 8018ea27e11b84e84804a2526768cbe3 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 9.2E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c32810 8018ea27e11b84e84804a2526768cbe3 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 9.2E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c32810 8018ea27e11b84e84804a2526768cbe3 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 9.2E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c32810 8018ea27e11b84e84804a2526768cbe3 146 SUPERFAMILY SSF46785 8 141 5.45E-29 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c32810 8018ea27e11b84e84804a2526768cbe3 146 Gene3D G3DSA:1.10.10.10 2 144 2.0E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c32810 8018ea27e11b84e84804a2526768cbe3 146 SMART SM00347 29 129 5.9E-19 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c05380 b6ec9deb4298621c2e77be6b2e21ba70 236 Hamap MF_00495 Phosphoglycolate phosphatase [gph]. 3 221 33.393 T 12-10-2018 IPR037512 Phosphoglycolate phosphatase, prokaryotic GO:0005975|GO:0008967 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 MIM_c05380 b6ec9deb4298621c2e77be6b2e21ba70 236 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 191 9.4E-35 T 12-10-2018 MIM_c05380 b6ec9deb4298621c2e77be6b2e21ba70 236 SUPERFAMILY SSF56784 1 222 1.76E-55 T 12-10-2018 IPR036412 HAD-like superfamily MIM_c05380 b6ec9deb4298621c2e77be6b2e21ba70 236 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 7 216 5.9E-63 T 12-10-2018 IPR006346 2-phosphoglycolate phosphatase-like, prokaryotic GO:0016791 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 MIM_c05380 b6ec9deb4298621c2e77be6b2e21ba70 236 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 96 190 1.8E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MIM_c05380 b6ec9deb4298621c2e77be6b2e21ba70 236 Gene3D G3DSA:1.10.150.240 18 90 1.0E-57 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MIM_c05380 b6ec9deb4298621c2e77be6b2e21ba70 236 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 105 185 5.7E-11 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MIM_c05380 b6ec9deb4298621c2e77be6b2e21ba70 236 Gene3D G3DSA:3.40.50.1000 7 211 1.0E-57 T 12-10-2018 IPR023214 HAD superfamily MIM_c05380 b6ec9deb4298621c2e77be6b2e21ba70 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 104 117 2.8E-9 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MIM_c05380 b6ec9deb4298621c2e77be6b2e21ba70 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 135 151 2.8E-9 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MIM_c05380 b6ec9deb4298621c2e77be6b2e21ba70 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 2.8E-9 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MIM_c05380 b6ec9deb4298621c2e77be6b2e21ba70 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 153 173 2.8E-9 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MIM_c05380 b6ec9deb4298621c2e77be6b2e21ba70 236 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 87 189 1.6E-14 T 12-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 MIM_c20650 921bd915cc2edef6a5db5344df43b998 233 Gene3D G3DSA:3.30.750.190 92 126 4.7E-19 T 12-10-2018 MIM_c20650 921bd915cc2edef6a5db5344df43b998 233 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 131 206 3.4E-13 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MIM_c20650 921bd915cc2edef6a5db5344df43b998 233 Gene3D G3DSA:1.10.1040.50 127 203 4.7E-19 T 12-10-2018 MIM_c20650 921bd915cc2edef6a5db5344df43b998 233 SUPERFAMILY SSF48179 128 206 7.4E-15 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c41110 69e63d38a8dd6e1d93efefc86830f01f 714 Pfam PF13549 ATP-grasp domain 497 707 2.8E-56 T 12-10-2018 MIM_c41110 69e63d38a8dd6e1d93efefc86830f01f 714 SUPERFAMILY SSF51735 20 155 2.31E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c41110 69e63d38a8dd6e1d93efefc86830f01f 714 SUPERFAMILY SSF56059 500 711 6.36E-26 T 12-10-2018 MIM_c41110 69e63d38a8dd6e1d93efefc86830f01f 714 Gene3D G3DSA:3.40.50.261 155 312 6.4E-46 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c41110 69e63d38a8dd6e1d93efefc86830f01f 714 Gene3D G3DSA:3.30.470.20 500 705 8.0E-61 T 12-10-2018 MIM_c41110 69e63d38a8dd6e1d93efefc86830f01f 714 SUPERFAMILY SSF52210 161 314 2.35E-36 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c41110 69e63d38a8dd6e1d93efefc86830f01f 714 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 173 309 5.4E-45 T 12-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain MIM_c41110 69e63d38a8dd6e1d93efefc86830f01f 714 Pfam PF13380 CoA binding domain 28 152 6.8E-16 T 12-10-2018 IPR003781 CoA-binding GO:0048037 MIM_c41110 69e63d38a8dd6e1d93efefc86830f01f 714 SMART SM00881 23 118 5.8E-19 T 12-10-2018 IPR003781 CoA-binding GO:0048037 MIM_c41110 69e63d38a8dd6e1d93efefc86830f01f 714 Gene3D G3DSA:3.40.50.720 21 147 9.0E-34 T 12-10-2018 MIM_c41110 69e63d38a8dd6e1d93efefc86830f01f 714 Gene3D G3DSA:3.30.1490.20 518 591 8.0E-61 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MIM_c41110 69e63d38a8dd6e1d93efefc86830f01f 714 SUPERFAMILY SSF52210 328 474 3.27E-15 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c41110 69e63d38a8dd6e1d93efefc86830f01f 714 Gene3D G3DSA:3.40.50.261 327 484 4.9E-16 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c01310 867334f86a30015172d97275fb026896 219 SUPERFAMILY SSF51735 2 205 2.48E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c01310 867334f86a30015172d97275fb026896 219 Gene3D G3DSA:3.40.50.720 4 219 1.6E-45 T 12-10-2018 MIM_c01310 867334f86a30015172d97275fb026896 219 Pfam PF13460 NAD(P)H-binding 8 193 8.3E-40 T 12-10-2018 IPR016040 NAD(P)-binding domain MIM_c02280 17d95328dff9ac7e995a22ae413a7a77 507 Gene3D G3DSA:3.40.605.10 25 493 2.1E-164 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c02280 17d95328dff9ac7e995a22ae413a7a77 507 Pfam PF00171 Aldehyde dehydrogenase family 29 493 1.3E-166 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c02280 17d95328dff9ac7e995a22ae413a7a77 507 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 296 307 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MIM_c02280 17d95328dff9ac7e995a22ae413a7a77 507 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 263 270 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MIM_c02280 17d95328dff9ac7e995a22ae413a7a77 507 SUPERFAMILY SSF53720 16 499 4.19E-164 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c02280 17d95328dff9ac7e995a22ae413a7a77 507 Gene3D G3DSA:3.40.309.10 268 465 2.1E-164 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MIM_c10870 1a7f245550958deb4e1c6ca22b07bb5e 100 Gene3D G3DSA:1.10.3230.30 1 95 5.3E-8 T 12-10-2018 MIM_c10870 1a7f245550958deb4e1c6ca22b07bb5e 100 Pfam PF05135 Phage gp6-like head-tail connector protein 4 75 1.7E-6 T 12-10-2018 IPR021146 Phage gp6-like head-tail connector protein MIM_c31290 58ba2a4babd697b25deef7f6aa499aa6 254 Pfam PF09836 Putative DNA-binding domain 7 96 9.8E-22 T 12-10-2018 IPR018640 Putative DNA-binding domain, bacteria MIM_c40840 ab03c25649acd63e56e90f9a6f177e24 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 17 28 7.1E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c40840 ab03c25649acd63e56e90f9a6f177e24 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 49 7.1E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c40840 ab03c25649acd63e56e90f9a6f177e24 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 38 7.1E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c40840 ab03c25649acd63e56e90f9a6f177e24 301 Gene3D G3DSA:3.40.190.290 90 294 2.1E-30 T 12-10-2018 MIM_c40840 ab03c25649acd63e56e90f9a6f177e24 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 2 61 5.9E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c40840 ab03c25649acd63e56e90f9a6f177e24 301 SUPERFAMILY SSF46785 3 77 1.14E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c40840 ab03c25649acd63e56e90f9a6f177e24 301 Gene3D G3DSA:1.10.10.10 1 89 3.1E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c40840 ab03c25649acd63e56e90f9a6f177e24 301 SUPERFAMILY SSF53850 89 290 3.1E-31 T 12-10-2018 MIM_c40840 ab03c25649acd63e56e90f9a6f177e24 301 Pfam PF03466 LysR substrate binding domain 86 287 3.3E-32 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c21850 6a6c171d640336746b51e8337095f963 519 Gene3D G3DSA:3.40.50.300 209 519 3.6E-54 T 12-10-2018 MIM_c21850 6a6c171d640336746b51e8337095f963 519 SUPERFAMILY SSF54211 10 181 1.86E-22 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MIM_c21850 6a6c171d640336746b51e8337095f963 519 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 8 514 1.4E-154 T 12-10-2018 IPR004482 Mg chelatase-related protein MIM_c21850 6a6c171d640336746b51e8337095f963 519 SUPERFAMILY SSF52540 213 514 4.22E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c21850 6a6c171d640336746b51e8337095f963 519 SMART SM00382 233 413 1.8E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c21850 6a6c171d640336746b51e8337095f963 519 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 139 7.6E-35 T 12-10-2018 MIM_c21850 6a6c171d640336746b51e8337095f963 519 Pfam PF01078 Magnesium chelatase, subunit ChlI 214 410 7.5E-88 T 12-10-2018 IPR000523 Magnesium chelatase ChlI domain MIM_c21850 6a6c171d640336746b51e8337095f963 519 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 423 514 8.1E-26 T 12-10-2018 IPR025158 Mg chelatase-related protein, C-terminal domain MIM_c21850 6a6c171d640336746b51e8337095f963 519 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 310 324 1.1E-5 T 12-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 MIM_c21850 6a6c171d640336746b51e8337095f963 519 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 338 351 1.1E-5 T 12-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 MIM_c21850 6a6c171d640336746b51e8337095f963 519 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 362 374 1.1E-5 T 12-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 MIM_c21850 6a6c171d640336746b51e8337095f963 519 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 232 247 1.1E-5 T 12-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 MIM_c18440 bf0c186ea0039bb6e3a8b9a05a162f99 346 Gene3D G3DSA:2.40.30.10 102 203 7.3E-22 T 12-10-2018 MIM_c18440 bf0c186ea0039bb6e3a8b9a05a162f99 346 SUPERFAMILY SSF63380 102 203 1.97E-20 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MIM_c18440 bf0c186ea0039bb6e3a8b9a05a162f99 346 SUPERFAMILY SSF54292 3 91 5.77E-27 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MIM_c18440 bf0c186ea0039bb6e3a8b9a05a162f99 346 Gene3D G3DSA:3.10.20.30 2 100 1.8E-25 T 12-10-2018 IPR012675 Beta-grasp domain superfamily MIM_c18440 bf0c186ea0039bb6e3a8b9a05a162f99 346 Gene3D G3DSA:3.40.50.80 204 339 9.3E-30 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MIM_c18440 bf0c186ea0039bb6e3a8b9a05a162f99 346 Pfam PF00970 Oxidoreductase FAD-binding domain 106 201 3.8E-12 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 MIM_c18440 bf0c186ea0039bb6e3a8b9a05a162f99 346 PRINTS PR00410 Phenol hydroxylase reductase family signature 132 144 3.2E-22 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MIM_c18440 bf0c186ea0039bb6e3a8b9a05a162f99 346 PRINTS PR00410 Phenol hydroxylase reductase family signature 196 205 3.2E-22 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MIM_c18440 bf0c186ea0039bb6e3a8b9a05a162f99 346 PRINTS PR00410 Phenol hydroxylase reductase family signature 212 231 3.2E-22 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MIM_c18440 bf0c186ea0039bb6e3a8b9a05a162f99 346 PRINTS PR00410 Phenol hydroxylase reductase family signature 304 312 3.2E-22 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MIM_c18440 bf0c186ea0039bb6e3a8b9a05a162f99 346 PRINTS PR00410 Phenol hydroxylase reductase family signature 148 155 3.2E-22 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MIM_c18440 bf0c186ea0039bb6e3a8b9a05a162f99 346 PRINTS PR00410 Phenol hydroxylase reductase family signature 237 246 3.2E-22 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MIM_c18440 bf0c186ea0039bb6e3a8b9a05a162f99 346 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MIM_c18440 bf0c186ea0039bb6e3a8b9a05a162f99 346 SUPERFAMILY SSF52343 204 338 2.62E-36 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MIM_c18440 bf0c186ea0039bb6e3a8b9a05a162f99 346 Pfam PF00175 Oxidoreductase NAD-binding domain 213 317 8.9E-20 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MIM_c18440 bf0c186ea0039bb6e3a8b9a05a162f99 346 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 148 155 3.7E-5 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MIM_c18440 bf0c186ea0039bb6e3a8b9a05a162f99 346 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 237 246 3.7E-5 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MIM_c18440 bf0c186ea0039bb6e3a8b9a05a162f99 346 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 212 231 3.7E-5 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MIM_c18440 bf0c186ea0039bb6e3a8b9a05a162f99 346 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 304 312 3.7E-5 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MIM_c18440 bf0c186ea0039bb6e3a8b9a05a162f99 346 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 82 1.7E-13 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MIM_c40630 3f989d9ee444ac85a6b23c7a74683764 1371 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 9 1366 0.0 T 12-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c40630 3f989d9ee444ac85a6b23c7a74683764 1371 Pfam PF00562 RNA polymerase Rpb2, domain 6 724 1292 2.1E-158 T 12-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c40630 3f989d9ee444ac85a6b23c7a74683764 1371 Pfam PF10385 RNA polymerase beta subunit external 1 domain 597 662 7.1E-25 T 12-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c40630 3f989d9ee444ac85a6b23c7a74683764 1371 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1370 12.226 T 12-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c40630 3f989d9ee444ac85a6b23c7a74683764 1371 Gene3D G3DSA:2.40.270.10 1054 1270 5.9E-81 T 12-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c40630 3f989d9ee444ac85a6b23c7a74683764 1371 Gene3D G3DSA:3.90.1800.10 1280 1362 9.0E-11 T 12-10-2018 MIM_c40630 3f989d9ee444ac85a6b23c7a74683764 1371 Gene3D G3DSA:2.40.50.150 839 959 3.5E-43 T 12-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c40630 3f989d9ee444ac85a6b23c7a74683764 1371 Gene3D G3DSA:2.40.50.100 720 794 1.7E-29 T 12-10-2018 MIM_c40630 3f989d9ee444ac85a6b23c7a74683764 1371 Pfam PF04561 RNA polymerase Rpb2, domain 2 155 229 1.5E-6 T 12-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c40630 3f989d9ee444ac85a6b23c7a74683764 1371 Pfam PF04561 RNA polymerase Rpb2, domain 2 358 460 3.4E-15 T 12-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c40630 3f989d9ee444ac85a6b23c7a74683764 1371 Gene3D G3DSA:2.40.270.10 796 838 1.2E-6 T 12-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c40630 3f989d9ee444ac85a6b23c7a74683764 1371 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1082 1094 - T 12-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c40630 3f989d9ee444ac85a6b23c7a74683764 1371 Pfam PF04565 RNA polymerase Rpb2, domain 3 519 586 1.2E-31 T 12-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c40630 3f989d9ee444ac85a6b23c7a74683764 1371 Gene3D G3DSA:3.90.1100.10 447 630 9.7E-72 T 12-10-2018 MIM_c40630 3f989d9ee444ac85a6b23c7a74683764 1371 Gene3D G3DSA:3.90.1110.10 321 446 2.1E-29 T 12-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c40630 3f989d9ee444ac85a6b23c7a74683764 1371 SUPERFAMILY SSF64484 12 1369 0.0 T 12-10-2018 MIM_c40630 3f989d9ee444ac85a6b23c7a74683764 1371 Pfam PF04563 RNA polymerase beta subunit 26 506 9.6E-38 T 12-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c40630 3f989d9ee444ac85a6b23c7a74683764 1371 Pfam PF04560 RNA polymerase Rpb2, domain 7 1294 1368 1.6E-25 T 12-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c40630 3f989d9ee444ac85a6b23c7a74683764 1371 Gene3D G3DSA:3.90.1100.10 650 719 2.0E-21 T 12-10-2018 MIM_c40630 3f989d9ee444ac85a6b23c7a74683764 1371 Gene3D G3DSA:3.90.1100.10 18 174 1.6E-53 T 12-10-2018 MIM_c37950 941fc3676dfe47dee11079e0be95e37b 272 Gene3D G3DSA:1.10.10.10 10 83 7.6E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c37950 941fc3676dfe47dee11079e0be95e37b 272 SUPERFAMILY SSF55781 83 257 3.14E-25 T 12-10-2018 MIM_c37950 941fc3676dfe47dee11079e0be95e37b 272 Pfam PF09339 IclR helix-turn-helix domain 12 62 2.6E-15 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c37950 941fc3676dfe47dee11079e0be95e37b 272 Gene3D G3DSA:3.30.450.40 84 258 2.1E-24 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c37950 941fc3676dfe47dee11079e0be95e37b 272 SUPERFAMILY SSF46785 12 80 5.0E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c37950 941fc3676dfe47dee11079e0be95e37b 272 SMART SM00346 9 93 1.7E-13 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c37950 941fc3676dfe47dee11079e0be95e37b 272 Pfam PF01614 Bacterial transcriptional regulator 148 254 8.4E-8 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal MIM_c22270 81de4edbab63da5b33166a6bc7d01bb2 865 Gene3D G3DSA:3.40.50.300 552 765 1.2E-86 T 12-10-2018 MIM_c22270 81de4edbab63da5b33166a6bc7d01bb2 865 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 60 1.0E-9 T 12-10-2018 IPR004176 Clp, N-terminal MIM_c22270 81de4edbab63da5b33166a6bc7d01bb2 865 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 145 4.0E-11 T 12-10-2018 IPR004176 Clp, N-terminal MIM_c22270 81de4edbab63da5b33166a6bc7d01bb2 865 Gene3D G3DSA:1.10.1780.10 1 146 6.8E-33 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 MIM_c22270 81de4edbab63da5b33166a6bc7d01bb2 865 Gene3D G3DSA:3.40.50.300 147 342 3.2E-74 T 12-10-2018 MIM_c22270 81de4edbab63da5b33166a6bc7d01bb2 865 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 856 0.0 T 12-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 MIM_c22270 81de4edbab63da5b33166a6bc7d01bb2 865 Pfam PF07724 AAA domain (Cdc48 subfamily) 598 761 1.3E-55 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MIM_c22270 81de4edbab63da5b33166a6bc7d01bb2 865 SMART SM01086 767 856 1.4E-37 T 12-10-2018 IPR019489 Clp ATPase, C-terminal MIM_c22270 81de4edbab63da5b33166a6bc7d01bb2 865 SMART SM00382 198 344 3.5E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c22270 81de4edbab63da5b33166a6bc7d01bb2 865 SMART SM00382 599 768 1.2E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c22270 81de4edbab63da5b33166a6bc7d01bb2 865 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 MIM_c22270 81de4edbab63da5b33166a6bc7d01bb2 865 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 767 847 1.7E-24 T 12-10-2018 IPR019489 Clp ATPase, C-terminal MIM_c22270 81de4edbab63da5b33166a6bc7d01bb2 865 Gene3D G3DSA:1.10.8.60 767 862 3.2E-27 T 12-10-2018 MIM_c22270 81de4edbab63da5b33166a6bc7d01bb2 865 SUPERFAMILY SSF52540 548 856 1.43E-83 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c22270 81de4edbab63da5b33166a6bc7d01bb2 865 SUPERFAMILY SSF52540 159 547 4.21E-100 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c22270 81de4edbab63da5b33166a6bc7d01bb2 865 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 633 651 - T 12-10-2018 IPR028299 ClpA/B, conserved site 2 MIM_c22270 81de4edbab63da5b33166a6bc7d01bb2 865 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 677 695 8.7E-43 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 MIM_c22270 81de4edbab63da5b33166a6bc7d01bb2 865 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 648 666 8.7E-43 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 MIM_c22270 81de4edbab63da5b33166a6bc7d01bb2 865 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 710 724 8.7E-43 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 MIM_c22270 81de4edbab63da5b33166a6bc7d01bb2 865 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 603 621 8.7E-43 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 MIM_c22270 81de4edbab63da5b33166a6bc7d01bb2 865 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 336 9.2E-14 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MIM_c22270 81de4edbab63da5b33166a6bc7d01bb2 865 SUPERFAMILY SSF81923 4 141 6.28E-37 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 MIM_c22270 81de4edbab63da5b33166a6bc7d01bb2 865 Gene3D G3DSA:3.40.50.300 343 546 2.4E-68 T 12-10-2018 MIM_c17080 6fd9cbf21b3971a3191e2ff7e53a0fd5 222 Gene3D G3DSA:2.60.120.590 20 221 1.8E-55 T 12-10-2018 IPR037151 Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily MIM_c17080 6fd9cbf21b3971a3191e2ff7e53a0fd5 222 SUPERFAMILY SSF51197 24 220 1.1E-59 T 12-10-2018 MIM_c17080 6fd9cbf21b3971a3191e2ff7e53a0fd5 222 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 48 219 8.9E-50 T 12-10-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like MIM_c40790 6b08dab3fb6bed963209be18b3c63ffa 391 Pfam PF00155 Aminotransferase class I and II 30 387 3.3E-55 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MIM_c40790 6b08dab3fb6bed963209be18b3c63ffa 391 SUPERFAMILY SSF53383 5 390 1.12E-94 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c40790 6b08dab3fb6bed963209be18b3c63ffa 391 Gene3D G3DSA:3.40.640.10 43 285 1.4E-129 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c40790 6b08dab3fb6bed963209be18b3c63ffa 391 Gene3D G3DSA:3.90.1150.10 15 384 1.4E-129 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c16910 f5890d1835a512ce9e46adfd0d78d2c7 314 Gene3D G3DSA:3.40.190.150 26 310 1.8E-85 T 12-10-2018 MIM_c16910 f5890d1835a512ce9e46adfd0d78d2c7 314 SUPERFAMILY SSF53850 105 280 7.33E-6 T 12-10-2018 MIM_c16910 f5890d1835a512ce9e46adfd0d78d2c7 314 Gene3D G3DSA:3.40.190.10 122 245 1.8E-85 T 12-10-2018 MIM_c16910 f5890d1835a512ce9e46adfd0d78d2c7 314 PIRSF PIRSF017082 3 314 1.5E-65 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c16910 f5890d1835a512ce9e46adfd0d78d2c7 314 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 310 1.6E-50 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c05190 d5045a056b6d1411ceff7ebb8faaf01d 464 SMART SM00997 224 383 2.4E-113 T 12-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MIM_c05190 d5045a056b6d1411ceff7ebb8faaf01d 464 Gene3D G3DSA:3.40.50.1480 5 464 3.0E-237 T 12-10-2018 MIM_c05190 d5045a056b6d1411ceff7ebb8faaf01d 464 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 5 456 1.8E-185 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MIM_c05190 d5045a056b6d1411ceff7ebb8faaf01d 464 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 76 90 - T 12-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MIM_c05190 d5045a056b6d1411ceff7ebb8faaf01d 464 SMART SM00996 4 463 0.0 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MIM_c05190 d5045a056b6d1411ceff7ebb8faaf01d 464 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 224 383 7.6E-81 T 12-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MIM_c05190 d5045a056b6d1411ceff7ebb8faaf01d 464 SUPERFAMILY SSF51735 224 383 1.26E-78 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c05190 d5045a056b6d1411ceff7ebb8faaf01d 464 SUPERFAMILY SSF52283 2 464 9.07E-113 T 12-10-2018 MIM_c05190 d5045a056b6d1411ceff7ebb8faaf01d 464 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 1 456 47.926 T 12-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 MIM_c05190 d5045a056b6d1411ceff7ebb8faaf01d 464 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 246 262 - T 12-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MIM_c05190 d5045a056b6d1411ceff7ebb8faaf01d 464 PIRSF PIRSF001109 1 464 3.9E-189 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MIM_c05190 d5045a056b6d1411ceff7ebb8faaf01d 464 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 4 463 7.1E-146 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MIM_c05190 d5045a056b6d1411ceff7ebb8faaf01d 464 Gene3D G3DSA:3.40.50.720 226 383 3.0E-237 T 12-10-2018 MIM_c36190 0e3ebbb39d1f39816326750184a0b08e 295 Pfam PF02678 Pirin 20 127 6.1E-35 T 12-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 MIM_c36190 0e3ebbb39d1f39816326750184a0b08e 295 SUPERFAMILY SSF51182 2 287 9.57E-87 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c36190 0e3ebbb39d1f39816326750184a0b08e 295 Pfam PF05726 Pirin C-terminal cupin domain 182 284 5.7E-28 T 12-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 MIM_c36190 0e3ebbb39d1f39816326750184a0b08e 295 Gene3D G3DSA:2.60.120.10 17 279 9.7E-85 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c36190 0e3ebbb39d1f39816326750184a0b08e 295 Gene3D G3DSA:2.60.120.10 149 253 9.7E-85 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c36190 0e3ebbb39d1f39816326750184a0b08e 295 PIRSF PIRSF006232 2 292 3.0E-92 T 12-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 MIM_c39030 04065d0453917cf4e493682516c88793 121 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 2 121 24.656 T 12-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c39030 04065d0453917cf4e493682516c88793 121 Gene3D G3DSA:3.30.420.100 1 121 2.9E-40 T 12-10-2018 MIM_c39030 04065d0453917cf4e493682516c88793 121 SUPERFAMILY SSF53137 3 119 2.4E-49 T 12-10-2018 MIM_c39030 04065d0453917cf4e493682516c88793 121 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 4 121 1.9E-33 T 12-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c39030 04065d0453917cf4e493682516c88793 121 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 1 121 2.0E-34 T 12-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c29710 85aa83aa4e0035843bff15cbe4b0d6cb 471 PIRSF PIRSF036426 1 464 2.4E-193 T 12-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MIM_c29710 85aa83aa4e0035843bff15cbe4b0d6cb 471 Gene3D G3DSA:3.40.1010.10 213 330 2.7E-45 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 MIM_c29710 85aa83aa4e0035843bff15cbe4b0d6cb 471 SUPERFAMILY SSF53790 214 449 1.01E-77 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 MIM_c29710 85aa83aa4e0035843bff15cbe4b0d6cb 471 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 295 328 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MIM_c29710 85aa83aa4e0035843bff15cbe4b0d6cb 471 Pfam PF10414 Sirohaem synthase dimerisation region 151 207 6.2E-20 T 12-10-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MIM_c29710 85aa83aa4e0035843bff15cbe4b0d6cb 471 Gene3D G3DSA:3.40.50.720 1 112 1.8E-32 T 12-10-2018 MIM_c29710 85aa83aa4e0035843bff15cbe4b0d6cb 471 Gene3D G3DSA:3.30.950.10 331 458 1.1E-41 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 MIM_c29710 85aa83aa4e0035843bff15cbe4b0d6cb 471 Pfam PF13241 Putative NAD(P)-binding 6 115 1.1E-28 T 12-10-2018 MIM_c29710 85aa83aa4e0035843bff15cbe4b0d6cb 471 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 217 426 8.6E-53 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 MIM_c29710 85aa83aa4e0035843bff15cbe4b0d6cb 471 SUPERFAMILY SSF51735 1 112 1.9E-24 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c29710 85aa83aa4e0035843bff15cbe4b0d6cb 471 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 207 1.3E-76 T 12-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MIM_c29710 85aa83aa4e0035843bff15cbe4b0d6cb 471 Gene3D G3DSA:3.30.160.110 113 148 8.2E-18 T 12-10-2018 MIM_c29710 85aa83aa4e0035843bff15cbe4b0d6cb 471 Gene3D G3DSA:1.10.8.210 149 208 1.0E-13 T 12-10-2018 IPR037115 Sirohaem synthase, dimerisation domain superfamily GO:0006779|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MIM_c29710 85aa83aa4e0035843bff15cbe4b0d6cb 471 SUPERFAMILY SSF75615 114 212 4.05E-26 T 12-10-2018 MIM_c29710 85aa83aa4e0035843bff15cbe4b0d6cb 471 Hamap MF_01646 Siroheme synthase [cysG]. 1 457 48.22 T 12-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MIM_c29710 85aa83aa4e0035843bff15cbe4b0d6cb 471 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 215 448 9.7E-93 T 12-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MIM_c29710 85aa83aa4e0035843bff15cbe4b0d6cb 471 Pfam PF14824 Sirohaem biosynthesis protein central 119 144 6.9E-7 T 12-10-2018 IPR028281 Siroheme synthase, central domain KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MIM_c25190 bc927d0a628e213fb0ee193c180f7748 329 Pfam PF00296 Luciferase-like monooxygenase 20 293 6.4E-37 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MIM_c25190 bc927d0a628e213fb0ee193c180f7748 329 Gene3D G3DSA:3.20.20.30 1 324 7.3E-95 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MIM_c25190 bc927d0a628e213fb0ee193c180f7748 329 SUPERFAMILY SSF51679 4 320 2.49E-76 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MIM_c25190 bc927d0a628e213fb0ee193c180f7748 329 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 4 321 4.1E-124 T 12-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 MIM_c00010 b63166b7ef157cea3a6dd718ad01ef0e 510 ProSitePatterns PS01008 DnaA protein signature. 468 487 - T 12-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 MIM_c00010 b63166b7ef157cea3a6dd718ad01ef0e 510 Gene3D G3DSA:1.10.1750.10 413 509 6.8E-35 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 MIM_c00010 b63166b7ef157cea3a6dd718ad01ef0e 510 Pfam PF11638 DnaA N-terminal domain 2 67 9.4E-13 T 12-10-2018 IPR024633 DnaA N-terminal domain MIM_c00010 b63166b7ef157cea3a6dd718ad01ef0e 510 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 419 487 6.0E-31 T 12-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 MIM_c00010 b63166b7ef157cea3a6dd718ad01ef0e 510 SUPERFAMILY SSF48295 407 509 8.11E-36 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 MIM_c00010 b63166b7ef157cea3a6dd718ad01ef0e 510 Gene3D G3DSA:3.30.300.180 2 109 6.7E-16 T 12-10-2018 IPR038454 DnaA, N-terminal domain superfamily MIM_c00010 b63166b7ef157cea3a6dd718ad01ef0e 510 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 2 509 30.05 T 12-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 MIM_c00010 b63166b7ef157cea3a6dd718ad01ef0e 510 SUPERFAMILY SSF52540 173 385 6.84E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c00010 b63166b7ef157cea3a6dd718ad01ef0e 510 Gene3D G3DSA:3.40.50.300 170 338 3.0E-44 T 12-10-2018 MIM_c00010 b63166b7ef157cea3a6dd718ad01ef0e 510 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 270 284 2.0E-46 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MIM_c00010 b63166b7ef157cea3a6dd718ad01ef0e 510 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 468 487 2.0E-46 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MIM_c00010 b63166b7ef157cea3a6dd718ad01ef0e 510 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 206 226 2.0E-46 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MIM_c00010 b63166b7ef157cea3a6dd718ad01ef0e 510 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 238 252 2.0E-46 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MIM_c00010 b63166b7ef157cea3a6dd718ad01ef0e 510 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 304 331 2.0E-46 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MIM_c00010 b63166b7ef157cea3a6dd718ad01ef0e 510 Gene3D G3DSA:1.10.8.60 339 412 1.8E-17 T 12-10-2018 MIM_c00010 b63166b7ef157cea3a6dd718ad01ef0e 510 SMART SM00760 418 487 1.9E-41 T 12-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 MIM_c00010 b63166b7ef157cea3a6dd718ad01ef0e 510 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 5 508 7.0E-154 T 12-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 MIM_c00010 b63166b7ef157cea3a6dd718ad01ef0e 510 Pfam PF00308 Bacterial dnaA protein 173 391 2.8E-79 T 12-10-2018 IPR013317 Chromosomal replication initiator protein DnaA MIM_c00010 b63166b7ef157cea3a6dd718ad01ef0e 510 SMART SM00382 205 336 1.7E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c19310 dbdadcb41da4f4c039b64e1dd2511586 867 Gene3D G3DSA:1.10.3210.10 419 556 4.7E-9 T 12-10-2018 MIM_c19310 dbdadcb41da4f4c039b64e1dd2511586 867 SUPERFAMILY SSF55021 790 843 5.64E-7 T 12-10-2018 MIM_c19310 dbdadcb41da4f4c039b64e1dd2511586 867 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 867 268.028 T 12-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 MIM_c19310 dbdadcb41da4f4c039b64e1dd2511586 867 Pfam PF01909 Nucleotidyltransferase domain 55 95 3.0E-5 T 12-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 MIM_c19310 dbdadcb41da4f4c039b64e1dd2511586 867 Gene3D G3DSA:3.30.70.260 789 865 5.4E-5 T 12-10-2018 MIM_c19310 dbdadcb41da4f4c039b64e1dd2511586 867 SUPERFAMILY SSF109604 405 529 2.12E-15 T 12-10-2018 MIM_c19310 dbdadcb41da4f4c039b64e1dd2511586 867 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 22 857 4.6E-217 T 12-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 MIM_c19310 dbdadcb41da4f4c039b64e1dd2511586 867 SUPERFAMILY SSF81301 38 157 6.87E-20 T 12-10-2018 MIM_c19310 dbdadcb41da4f4c039b64e1dd2511586 867 SMART SM00471 434 581 4.3E-6 T 12-10-2018 IPR003607 HD/PDEase domain MIM_c19310 dbdadcb41da4f4c039b64e1dd2511586 867 SUPERFAMILY SSF55021 673 726 3.52E-9 T 12-10-2018 MIM_c19310 dbdadcb41da4f4c039b64e1dd2511586 867 Pfam PF08335 GlnD PII-uridylyltransferase 164 297 4.4E-24 T 12-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 MIM_c19310 dbdadcb41da4f4c039b64e1dd2511586 867 PIRSF PIRSF006288 2 867 3.3E-277 T 12-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 MIM_c19310 dbdadcb41da4f4c039b64e1dd2511586 867 Pfam PF01966 HD domain 439 549 2.3E-7 T 12-10-2018 IPR006674 HD domain MIM_c08960 66fc9e1cbf1c323ce7bcf52e4e5fc359 295 SMART SM00342 209 290 1.4E-27 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c08960 66fc9e1cbf1c323ce7bcf52e4e5fc359 295 Pfam PF14525 AraC-binding-like domain 26 120 2.7E-7 T 12-10-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like MIM_c08960 66fc9e1cbf1c323ce7bcf52e4e5fc359 295 SUPERFAMILY SSF46689 246 291 6.72E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c08960 66fc9e1cbf1c323ce7bcf52e4e5fc359 295 Gene3D G3DSA:1.10.10.60 193 293 7.6E-24 T 12-10-2018 MIM_c08960 66fc9e1cbf1c323ce7bcf52e4e5fc359 295 Pfam PF12833 Helix-turn-helix domain 215 291 1.4E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c08960 66fc9e1cbf1c323ce7bcf52e4e5fc359 295 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 259 274 1.7E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MIM_c08960 66fc9e1cbf1c323ce7bcf52e4e5fc359 295 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 274 290 1.7E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MIM_c08960 66fc9e1cbf1c323ce7bcf52e4e5fc359 295 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 246 286 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MIM_c08960 66fc9e1cbf1c323ce7bcf52e4e5fc359 295 SUPERFAMILY SSF46689 193 240 1.08E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c14490 0f793e4284cffd0290917534a9e9ae9e 106 Pfam PF04341 Protein of unknown function, DUF485 11 98 5.0E-27 T 12-10-2018 IPR007436 Protein of unknown function DUF485 MIM_c09840 8a3f8ed271bc4006c80fb2c61308e228 336 Gene3D G3DSA:2.70.70.10 132 287 4.3E-50 T 12-10-2018 IPR011055 Duplicated hybrid motif MIM_c09840 8a3f8ed271bc4006c80fb2c61308e228 336 Pfam PF01551 Peptidase family M23 185 278 2.7E-33 T 12-10-2018 IPR016047 Peptidase M23 MIM_c09840 8a3f8ed271bc4006c80fb2c61308e228 336 SUPERFAMILY SSF51261 159 282 2.46E-56 T 12-10-2018 IPR011055 Duplicated hybrid motif MIM_c20130 b26c47a14ed938fda0506b53be22d013 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 316 2.7E-67 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c20130 b26c47a14ed938fda0506b53be22d013 320 PIRSF PIRSF017082 1 318 3.2E-66 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c20130 b26c47a14ed938fda0506b53be22d013 320 Gene3D G3DSA:3.40.190.10 123 245 6.2E-91 T 12-10-2018 MIM_c20130 b26c47a14ed938fda0506b53be22d013 320 Gene3D G3DSA:3.40.190.150 28 310 6.2E-91 T 12-10-2018 MIM_c20130 b26c47a14ed938fda0506b53be22d013 320 SUPERFAMILY SSF53850 94 283 2.52E-10 T 12-10-2018 MIM_c40450 43df207facb0a06c2c21f171c6141294 418 SUPERFAMILY SSF51905 9 366 3.79E-47 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c40450 43df207facb0a06c2c21f171c6141294 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 11 33 2.1E-7 T 12-10-2018 MIM_c40450 43df207facb0a06c2c21f171c6141294 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 158 173 2.1E-7 T 12-10-2018 MIM_c40450 43df207facb0a06c2c21f171c6141294 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 306 2.1E-7 T 12-10-2018 MIM_c40450 43df207facb0a06c2c21f171c6141294 418 Gene3D G3DSA:3.50.50.60 7 417 9.6E-130 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c40450 43df207facb0a06c2c21f171c6141294 418 Pfam PF01494 FAD binding domain 10 338 3.1E-21 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 MIM_c06590 c0a064af5ce12d95f7d9f480fa44be0d 165 SUPERFAMILY SSF55781 17 155 3.93E-38 T 12-10-2018 MIM_c06590 c0a064af5ce12d95f7d9f480fa44be0d 165 Pfam PF13185 GAF domain 55 154 9.5E-10 T 12-10-2018 IPR003018 GAF domain GO:0005515 MIM_c06590 c0a064af5ce12d95f7d9f480fa44be0d 165 Gene3D G3DSA:3.30.450.40 13 164 9.5E-61 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c06590 c0a064af5ce12d95f7d9f480fa44be0d 165 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 100 117 - T 12-10-2018 IPR000614 Free Met sulfoxide reductase conserved site MIM_c28510 a3e985d24f38d211791006d53a0ea6cd 368 SMART SM00729 38 251 3.7E-9 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MIM_c28510 a3e985d24f38d211791006d53a0ea6cd 368 Pfam PF06463 Molybdenum Cofactor Synthesis C 220 345 9.7E-36 T 12-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MIM_c28510 a3e985d24f38d211791006d53a0ea6cd 368 Pfam PF13394 4Fe-4S single cluster domain 45 139 2.9E-8 T 12-10-2018 MIM_c28510 a3e985d24f38d211791006d53a0ea6cd 368 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 30 368 7.2E-117 T 12-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MIM_c28510 a3e985d24f38d211791006d53a0ea6cd 368 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 29 368 40.691 T 12-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MIM_c28510 a3e985d24f38d211791006d53a0ea6cd 368 Gene3D G3DSA:3.20.20.70 27 368 1.5E-97 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c28510 a3e985d24f38d211791006d53a0ea6cd 368 Pfam PF04055 Radical SAM superfamily 42 211 7.0E-29 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MIM_c28510 a3e985d24f38d211791006d53a0ea6cd 368 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 44 55 - T 12-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MIM_c28510 a3e985d24f38d211791006d53a0ea6cd 368 SUPERFAMILY SSF102114 28 311 1.1E-74 T 12-10-2018 MIM_c08260 6ccd528c28328ba06ad19da1c09a9a41 321 Gene3D G3DSA:3.40.190.10 122 245 1.6E-88 T 12-10-2018 MIM_c08260 6ccd528c28328ba06ad19da1c09a9a41 321 PIRSF PIRSF017082 6 314 1.0E-60 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c08260 6ccd528c28328ba06ad19da1c09a9a41 321 Gene3D G3DSA:3.40.190.150 26 305 1.6E-88 T 12-10-2018 MIM_c08260 6ccd528c28328ba06ad19da1c09a9a41 321 SUPERFAMILY SSF53850 111 281 1.29E-10 T 12-10-2018 MIM_c08260 6ccd528c28328ba06ad19da1c09a9a41 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 307 4.4E-58 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c21360 914984d8faad4e096898a117bb2c13fc 552 SUPERFAMILY SSF52402 273 535 9.92E-79 T 12-10-2018 MIM_c21360 914984d8faad4e096898a117bb2c13fc 552 Gene3D G3DSA:3.60.110.10 1 254 3.4E-82 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MIM_c21360 914984d8faad4e096898a117bb2c13fc 552 Hamap MF_02090 Glutamine-dependent NAD(+) synthetase [nadE]. 5 552 29.061 T 12-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MIM_c21360 914984d8faad4e096898a117bb2c13fc 552 TIGRFAM TIGR00552 nadE: NAD+ synthetase 286 532 1.7E-62 T 12-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 MIM_c21360 914984d8faad4e096898a117bb2c13fc 552 SUPERFAMILY SSF56317 4 245 2.49E-54 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MIM_c21360 914984d8faad4e096898a117bb2c13fc 552 Gene3D G3DSA:3.40.50.620 276 551 9.6E-117 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c21360 914984d8faad4e096898a117bb2c13fc 552 Pfam PF00795 Carbon-nitrogen hydrolase 7 251 2.7E-24 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 MIM_c21360 914984d8faad4e096898a117bb2c13fc 552 PIRSF PIRSF006630 2 552 6.6E-193 T 12-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MIM_c21360 914984d8faad4e096898a117bb2c13fc 552 Pfam PF02540 NAD synthase 279 526 1.3E-72 T 12-10-2018 IPR022310 NAD/GMP synthase MIM_c03560 6aff1fd036abd9653c79217eab0407ca 567 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 40 56 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MIM_c03560 6aff1fd036abd9653c79217eab0407ca 567 Pfam PF00682 HMGL-like 33 311 2.1E-78 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 MIM_c03560 6aff1fd036abd9653c79217eab0407ca 567 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 243 256 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MIM_c03560 6aff1fd036abd9653c79217eab0407ca 567 Pfam PF08502 LeuA allosteric (dimerisation) domain 423 552 3.6E-26 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MIM_c03560 6aff1fd036abd9653c79217eab0407ca 567 SUPERFAMILY SSF89000 388 437 1.8E-13 T 12-10-2018 MIM_c03560 6aff1fd036abd9653c79217eab0407ca 567 SMART SM00917 422 553 5.9E-26 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MIM_c03560 6aff1fd036abd9653c79217eab0407ca 567 Gene3D G3DSA:3.20.20.70 13 376 1.0E-153 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c03560 6aff1fd036abd9653c79217eab0407ca 567 SUPERFAMILY SSF110921 449 552 3.14E-30 T 12-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MIM_c03560 6aff1fd036abd9653c79217eab0407ca 567 Gene3D G3DSA:3.30.160.270 377 552 6.2E-57 T 12-10-2018 MIM_c03560 6aff1fd036abd9653c79217eab0407ca 567 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 6 554 52.307 T 12-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MIM_c03560 6aff1fd036abd9653c79217eab0407ca 567 SUPERFAMILY SSF51569 22 330 4.21E-101 T 12-10-2018 MIM_c03560 6aff1fd036abd9653c79217eab0407ca 567 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 5 552 1.2E-241 T 12-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MIM_c27810 955b163aa4e1f0506e63b0b6763658ec 263 PIRSF PIRSF015601 3 262 3.4E-51 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 MIM_c27810 955b163aa4e1f0506e63b0b6763658ec 263 Gene3D G3DSA:3.40.1280.10 74 261 8.5E-56 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MIM_c27810 955b163aa4e1f0506e63b0b6763658ec 263 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 5 260 9.9E-44 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 MIM_c27810 955b163aa4e1f0506e63b0b6763658ec 263 Gene3D G3DSA:2.40.240.20 1 65 6.0E-16 T 12-10-2018 MIM_c27810 955b163aa4e1f0506e63b0b6763658ec 263 SUPERFAMILY SSF88697 4 56 6.21E-12 T 12-10-2018 IPR015947 PUA-like superfamily MIM_c27810 955b163aa4e1f0506e63b0b6763658ec 263 SUPERFAMILY SSF75217 75 261 2.88E-42 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases MIM_c27810 955b163aa4e1f0506e63b0b6763658ec 263 Pfam PF04452 RNA methyltransferase 20 256 5.1E-59 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 MIM_c33970 9d9f202e0da839411ae69d10a85c8289 391 SUPERFAMILY SSF53955 188 369 1.07E-13 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily MIM_c33970 9d9f202e0da839411ae69d10a85c8289 391 Gene3D G3DSA:1.10.530.40 200 382 6.3E-27 T 12-10-2018 MIM_c16730 968805b2be24085d092b64e382ebc7ca 376 PIRSF PIRSF000148 2 376 9.5E-62 T 12-10-2018 MIM_c16730 968805b2be24085d092b64e382ebc7ca 376 SUPERFAMILY SSF51735 4 148 1.85E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c16730 968805b2be24085d092b64e382ebc7ca 376 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 122 1.5E-21 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MIM_c16730 968805b2be24085d092b64e382ebc7ca 376 SMART SM00859 4 123 2.2E-21 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MIM_c16730 968805b2be24085d092b64e382ebc7ca 376 SUPERFAMILY SSF55347 135 360 2.36E-72 T 12-10-2018 MIM_c16730 968805b2be24085d092b64e382ebc7ca 376 Gene3D G3DSA:3.40.50.720 1 140 1.9E-57 T 12-10-2018 MIM_c16730 968805b2be24085d092b64e382ebc7ca 376 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 145 359 3.1E-54 T 12-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MIM_c16730 968805b2be24085d092b64e382ebc7ca 376 Gene3D G3DSA:3.30.360.10 141 356 1.1E-79 T 12-10-2018 MIM_c16730 968805b2be24085d092b64e382ebc7ca 376 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 2 373 31.699 T 12-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MIM_c16730 968805b2be24085d092b64e382ebc7ca 376 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 267 281 - T 12-10-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MIM_c16730 968805b2be24085d092b64e382ebc7ca 376 TIGRFAM TIGR01745 asd_gamma: aspartate-semialdehyde dehydrogenase 4 371 6.0E-180 T 12-10-2018 IPR011534 Aspartate-semialdehyde dehydrogenase, gamma-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MIM_c32340 0e7b01ecd56c8023a8492e36b429df9a 283 SUPERFAMILY SSF74653 172 275 9.55E-21 T 12-10-2018 MIM_c32340 0e7b01ecd56c8023a8492e36b429df9a 283 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 196 273 1.6E-15 T 12-10-2018 IPR037682 TonB, C-terminal GO:0055085 MIM_c32340 0e7b01ecd56c8023a8492e36b429df9a 283 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 196 274 4.2E-19 T 12-10-2018 IPR006260 TonB/TolA, C-terminal MIM_c32340 0e7b01ecd56c8023a8492e36b429df9a 283 Gene3D G3DSA:3.30.1150.10 136 276 2.0E-29 T 12-10-2018 MIM_c13450 53c035ea5634d24828bc3812a6654932 320 PIRSF PIRSF017082 2 320 2.7E-89 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c13450 53c035ea5634d24828bc3812a6654932 320 Gene3D G3DSA:3.40.190.150 25 311 1.1E-113 T 12-10-2018 MIM_c13450 53c035ea5634d24828bc3812a6654932 320 Gene3D G3DSA:3.40.190.10 123 246 1.1E-113 T 12-10-2018 MIM_c13450 53c035ea5634d24828bc3812a6654932 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 317 1.0E-89 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c13450 53c035ea5634d24828bc3812a6654932 320 SUPERFAMILY SSF53850 110 285 2.67E-11 T 12-10-2018 MIM_c22310 ae5e01ecb7c5cb28a9a8b96e5cfabc07 268 SMART SM00079 38 253 0.0039 T 12-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 MIM_c22310 ae5e01ecb7c5cb28a9a8b96e5cfabc07 268 Gene3D G3DSA:3.40.190.10 30 250 2.5E-56 T 12-10-2018 MIM_c22310 ae5e01ecb7c5cb28a9a8b96e5cfabc07 268 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 255 5.8E-51 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c22310 ae5e01ecb7c5cb28a9a8b96e5cfabc07 268 SMART SM00062 38 258 6.1E-42 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c22310 ae5e01ecb7c5cb28a9a8b96e5cfabc07 268 SUPERFAMILY SSF53850 11 257 1.07E-57 T 12-10-2018 MIM_c22310 ae5e01ecb7c5cb28a9a8b96e5cfabc07 268 Gene3D G3DSA:3.40.190.10 125 216 2.5E-56 T 12-10-2018 MIM_c29720 7d472d14a878c8499e81453206996725 637 Pfam PF01964 Radical SAM ThiC family 139 598 1.1E-197 T 12-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MIM_c29720 7d472d14a878c8499e81453206996725 637 Gene3D G3DSA:3.20.20.540 221 534 1.1E-152 T 12-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MIM_c29720 7d472d14a878c8499e81453206996725 637 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 137 603 99.138 T 12-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MIM_c29720 7d472d14a878c8499e81453206996725 637 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 137 601 3.7E-212 T 12-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MIM_c29720 7d472d14a878c8499e81453206996725 637 Pfam PF13667 ThiC-associated domain 22 98 3.0E-32 T 12-10-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MIM_c40040 6c680a70a1f0a3f3bb040c21f68a7e71 103 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 12-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c40040 6c680a70a1f0a3f3bb040c21f68a7e71 103 Gene3D G3DSA:3.30.70.600 1 103 1.1E-37 T 12-10-2018 IPR036838 Ribosomal protein S10 domain superfamily MIM_c40040 6c680a70a1f0a3f3bb040c21f68a7e71 103 Pfam PF00338 Ribosomal protein S10p/S20e 7 100 2.5E-36 T 12-10-2018 IPR027486 Ribosomal protein S10 domain MIM_c40040 6c680a70a1f0a3f3bb040c21f68a7e71 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.59 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c40040 6c680a70a1f0a3f3bb040c21f68a7e71 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 4.3E-46 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c40040 6c680a70a1f0a3f3bb040c21f68a7e71 103 SMART SM01403 7 101 1.5E-56 T 12-10-2018 IPR027486 Ribosomal protein S10 domain MIM_c40040 6c680a70a1f0a3f3bb040c21f68a7e71 103 SUPERFAMILY SSF54999 5 101 4.45E-38 T 12-10-2018 IPR036838 Ribosomal protein S10 domain superfamily MIM_c40040 6c680a70a1f0a3f3bb040c21f68a7e71 103 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 2.3E-18 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c40040 6c680a70a1f0a3f3bb040c21f68a7e71 103 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 2.3E-18 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c40040 6c680a70a1f0a3f3bb040c21f68a7e71 103 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 2.3E-18 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c21570 f9db96b29a19c001c5eb3952e19efe13 114 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 4 113 1.1E-44 T 12-10-2018 IPR004624 PhnA protein MIM_c21570 f9db96b29a19c001c5eb3952e19efe13 114 Gene3D G3DSA:2.20.25.10 1 44 1.3E-14 T 12-10-2018 MIM_c21570 f9db96b29a19c001c5eb3952e19efe13 114 SUPERFAMILY SSF57783 3 35 6.46E-10 T 12-10-2018 MIM_c21570 f9db96b29a19c001c5eb3952e19efe13 114 Pfam PF03831 PhnA domain 47 114 3.5E-33 T 12-10-2018 IPR013988 PhnA protein, C-terminal MIM_c21570 f9db96b29a19c001c5eb3952e19efe13 114 Pfam PF08274 PhnA Zinc-Ribbon 3 33 1.0E-10 T 12-10-2018 IPR013987 PhnA protein, N-terminal MIM_c21570 f9db96b29a19c001c5eb3952e19efe13 114 SUPERFAMILY SSF82057 42 114 8.24E-29 T 12-10-2018 MIM_c21570 f9db96b29a19c001c5eb3952e19efe13 114 Gene3D G3DSA:2.30.30.40 45 114 2.7E-35 T 12-10-2018 MIM_c25440 1fbb060e164c18906e10e89786170e2f 323 Gene3D G3DSA:3.40.190.10 126 248 4.7E-106 T 12-10-2018 MIM_c25440 1fbb060e164c18906e10e89786170e2f 323 SUPERFAMILY SSF53850 112 280 9.05E-14 T 12-10-2018 MIM_c25440 1fbb060e164c18906e10e89786170e2f 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 319 2.0E-78 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c25440 1fbb060e164c18906e10e89786170e2f 323 Gene3D G3DSA:3.40.190.150 29 313 4.7E-106 T 12-10-2018 MIM_c25440 1fbb060e164c18906e10e89786170e2f 323 PIRSF PIRSF017082 1 323 3.4E-75 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c31160 3c897f3ae7a2f09230bf91fd3154417c 300 Gene3D G3DSA:3.40.190.290 94 294 5.9E-51 T 12-10-2018 MIM_c31160 3c897f3ae7a2f09230bf91fd3154417c 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 3.1E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c31160 3c897f3ae7a2f09230bf91fd3154417c 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 3.1E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c31160 3c897f3ae7a2f09230bf91fd3154417c 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 3.1E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c31160 3c897f3ae7a2f09230bf91fd3154417c 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 2.1E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c31160 3c897f3ae7a2f09230bf91fd3154417c 300 Gene3D G3DSA:1.10.10.10 4 93 1.9E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c31160 3c897f3ae7a2f09230bf91fd3154417c 300 SUPERFAMILY SSF53850 90 294 1.34E-39 T 12-10-2018 MIM_c31160 3c897f3ae7a2f09230bf91fd3154417c 300 SUPERFAMILY SSF46785 5 90 1.26E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c31160 3c897f3ae7a2f09230bf91fd3154417c 300 Pfam PF03466 LysR substrate binding domain 90 294 4.6E-35 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c09250 9471b2074081b14c5fc32c13829d02bd 1041 Gene3D G3DSA:3.30.70.1320 135 326 2.2E-283 T 12-10-2018 MIM_c09250 9471b2074081b14c5fc32c13829d02bd 1041 Gene3D G3DSA:3.30.70.1430 40 800 2.2E-283 T 12-10-2018 MIM_c09250 9471b2074081b14c5fc32c13829d02bd 1041 Gene3D G3DSA:3.30.70.1440 652 851 2.2E-283 T 12-10-2018 MIM_c09250 9471b2074081b14c5fc32c13829d02bd 1041 SUPERFAMILY SSF82866 814 1014 6.93E-42 T 12-10-2018 MIM_c09250 9471b2074081b14c5fc32c13829d02bd 1041 PRINTS PR00702 Acriflavin resistance protein family signature 543 560 3.8E-79 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09250 9471b2074081b14c5fc32c13829d02bd 1041 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 3.8E-79 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09250 9471b2074081b14c5fc32c13829d02bd 1041 PRINTS PR00702 Acriflavin resistance protein family signature 607 621 3.8E-79 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09250 9471b2074081b14c5fc32c13829d02bd 1041 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 3.8E-79 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09250 9471b2074081b14c5fc32c13829d02bd 1041 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 3.8E-79 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09250 9471b2074081b14c5fc32c13829d02bd 1041 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 3.8E-79 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09250 9471b2074081b14c5fc32c13829d02bd 1041 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 3.8E-79 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09250 9471b2074081b14c5fc32c13829d02bd 1041 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 3.8E-79 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09250 9471b2074081b14c5fc32c13829d02bd 1041 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 3.8E-79 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09250 9471b2074081b14c5fc32c13829d02bd 1041 SUPERFAMILY SSF82693 556 652 9.68E-15 T 12-10-2018 MIM_c09250 9471b2074081b14c5fc32c13829d02bd 1041 SUPERFAMILY SSF82866 291 490 1.18E-45 T 12-10-2018 MIM_c09250 9471b2074081b14c5fc32c13829d02bd 1041 Gene3D G3DSA:3.30.2090.10 704 792 2.2E-283 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c09250 9471b2074081b14c5fc32c13829d02bd 1041 Pfam PF00873 AcrB/AcrD/AcrF family 5 1012 0.0 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09250 9471b2074081b14c5fc32c13829d02bd 1041 SUPERFAMILY SSF82714 183 265 1.31E-15 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c09250 9471b2074081b14c5fc32c13829d02bd 1041 SUPERFAMILY SSF82693 137 324 5.75E-20 T 12-10-2018 MIM_c09250 9471b2074081b14c5fc32c13829d02bd 1041 Gene3D G3DSA:3.30.70.1430 558 651 2.2E-283 T 12-10-2018 MIM_c09250 9471b2074081b14c5fc32c13829d02bd 1041 SUPERFAMILY SSF82714 707 790 3.92E-13 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c09250 9471b2074081b14c5fc32c13829d02bd 1041 SUPERFAMILY SSF82693 41 128 1.7E-21 T 12-10-2018 MIM_c09250 9471b2074081b14c5fc32c13829d02bd 1041 Gene3D G3DSA:3.30.2090.10 179 269 2.2E-283 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c09250 9471b2074081b14c5fc32c13829d02bd 1041 SUPERFAMILY SSF82693 664 836 2.35E-8 T 12-10-2018 MIM_c09250 9471b2074081b14c5fc32c13829d02bd 1041 Gene3D G3DSA:1.20.1640.10 10 503 2.2E-283 T 12-10-2018 MIM_c09250 9471b2074081b14c5fc32c13829d02bd 1041 Gene3D G3DSA:1.20.1640.10 504 1009 2.2E-283 T 12-10-2018 MIM_c01350 29e35ed57ff86c70915c8c31c4ec32f9 285 Gene3D G3DSA:3.20.20.70 120 273 3.1E-103 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c01350 29e35ed57ff86c70915c8c31c4ec32f9 285 SUPERFAMILY SSF54675 5 116 2.86E-32 T 12-10-2018 MIM_c01350 29e35ed57ff86c70915c8c31c4ec32f9 285 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 28 115 3.3E-26 T 12-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 MIM_c01350 29e35ed57ff86c70915c8c31c4ec32f9 285 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 17 283 1.8E-96 T 12-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 MIM_c01350 29e35ed57ff86c70915c8c31c4ec32f9 285 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 117 282 2.9E-57 T 12-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 MIM_c01350 29e35ed57ff86c70915c8c31c4ec32f9 285 PIRSF PIRSF006250 11 285 2.0E-90 T 12-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 MIM_c01350 29e35ed57ff86c70915c8c31c4ec32f9 285 Gene3D G3DSA:3.90.1170.20 19 282 3.1E-103 T 12-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 MIM_c01350 29e35ed57ff86c70915c8c31c4ec32f9 285 SUPERFAMILY SSF51690 117 283 4.32E-56 T 12-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MIM_c14350 0a15cec5c7eb379584d75eae8c25bd17 360 ProSitePatterns PS00124 Fructose-1-6-bisphosphatase active site. 276 288 - T 12-10-2018 IPR020548 Fructose-1,6-bisphosphatase, active site GO:0005975|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MIM_c14350 0a15cec5c7eb379584d75eae8c25bd17 360 PIRSF PIRSF000904 3 340 6.6E-122 T 12-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MIM_c14350 0a15cec5c7eb379584d75eae8c25bd17 360 PIRSF PIRSF500210 3 339 8.5E-123 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MIM_c14350 0a15cec5c7eb379584d75eae8c25bd17 360 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 7 336 45.366 T 12-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MIM_c14350 0a15cec5c7eb379584d75eae8c25bd17 360 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 8 197 4.3E-58 T 12-10-2018 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MIM_c14350 0a15cec5c7eb379584d75eae8c25bd17 360 Gene3D G3DSA:3.30.540.10 7 198 3.0E-69 T 12-10-2018 MIM_c14350 0a15cec5c7eb379584d75eae8c25bd17 360 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 32 59 1.1E-63 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MIM_c14350 0a15cec5c7eb379584d75eae8c25bd17 360 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 69 95 1.1E-63 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MIM_c14350 0a15cec5c7eb379584d75eae8c25bd17 360 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 151 174 1.1E-63 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MIM_c14350 0a15cec5c7eb379584d75eae8c25bd17 360 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 182 205 1.1E-63 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MIM_c14350 0a15cec5c7eb379584d75eae8c25bd17 360 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 310 335 1.1E-63 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MIM_c14350 0a15cec5c7eb379584d75eae8c25bd17 360 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 208 235 1.1E-63 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MIM_c14350 0a15cec5c7eb379584d75eae8c25bd17 360 Gene3D G3DSA:3.40.190.80 200 339 2.1E-51 T 12-10-2018 MIM_c14350 0a15cec5c7eb379584d75eae8c25bd17 360 SUPERFAMILY SSF56655 5 334 1.28E-108 T 12-10-2018 MIM_c32730 b0c7d259a0d7cc24f4791d01340495b4 415 SUPERFAMILY SSF50249 35 130 4.8E-17 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c32730 b0c7d259a0d7cc24f4791d01340495b4 415 Gene3D G3DSA:3.40.50.720 170 398 6.9E-27 T 12-10-2018 MIM_c32730 b0c7d259a0d7cc24f4791d01340495b4 415 Pfam PF00106 short chain dehydrogenase 170 359 3.2E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c32730 b0c7d259a0d7cc24f4791d01340495b4 415 SUPERFAMILY SSF51735 163 394 3.93E-27 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c32730 b0c7d259a0d7cc24f4791d01340495b4 415 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 321 340 5.0E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c32730 b0c7d259a0d7cc24f4791d01340495b4 415 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 241 252 5.0E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c32730 b0c7d259a0d7cc24f4791d01340495b4 415 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 5.0E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c32730 b0c7d259a0d7cc24f4791d01340495b4 415 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 37 70 1.2E-8 T 12-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal MIM_c32730 b0c7d259a0d7cc24f4791d01340495b4 415 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 72 132 2.5E-6 T 12-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal MIM_c02300 0484c1c5220b6b804b02788db1e07d95 779 Gene3D G3DSA:3.90.1170.50 203 319 9.5E-13 T 12-10-2018 MIM_c02300 0484c1c5220b6b804b02788db1e07d95 779 SMART SM01008 232 321 8.9E-31 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MIM_c02300 0484c1c5220b6b804b02788db1e07d95 779 Gene3D G3DSA:3.30.365.10 374 466 2.3E-48 T 12-10-2018 MIM_c02300 0484c1c5220b6b804b02788db1e07d95 779 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 637 722 8.4E-16 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MIM_c02300 0484c1c5220b6b804b02788db1e07d95 779 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 71 202 7.8E-14 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MIM_c02300 0484c1c5220b6b804b02788db1e07d95 779 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 342 628 2.2E-30 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MIM_c02300 0484c1c5220b6b804b02788db1e07d95 779 SUPERFAMILY SSF56003 67 266 3.49E-41 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 MIM_c02300 0484c1c5220b6b804b02788db1e07d95 779 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 232 282 2.3E-6 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MIM_c02300 0484c1c5220b6b804b02788db1e07d95 779 PIRSF PIRSF036389 11 779 3.1E-250 T 12-10-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related MIM_c02300 0484c1c5220b6b804b02788db1e07d95 779 Gene3D G3DSA:3.30.365.10 626 778 5.9E-38 T 12-10-2018 MIM_c02300 0484c1c5220b6b804b02788db1e07d95 779 Gene3D G3DSA:3.30.365.10 350 573 2.3E-48 T 12-10-2018 MIM_c02300 0484c1c5220b6b804b02788db1e07d95 779 SUPERFAMILY SSF56003 346 771 1.28E-104 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 MIM_c02300 0484c1c5220b6b804b02788db1e07d95 779 Gene3D G3DSA:3.30.365.10 65 202 9.0E-22 T 12-10-2018 MIM_c33420 f091c002d597741e54934cfc76b16b5e 254 Gene3D G3DSA:3.40.50.720 11 254 9.5E-76 T 12-10-2018 MIM_c33420 f091c002d597741e54934cfc76b16b5e 254 SUPERFAMILY SSF51735 12 254 6.22E-73 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c33420 f091c002d597741e54934cfc76b16b5e 254 Pfam PF00106 short chain dehydrogenase 15 209 2.4E-54 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c33420 f091c002d597741e54934cfc76b16b5e 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 14 206 0.0055 T 12-10-2018 MIM_c33420 f091c002d597741e54934cfc76b16b5e 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 153 181 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c33420 f091c002d597741e54934cfc76b16b5e 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 5.1E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c33420 f091c002d597741e54934cfc76b16b5e 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 5.1E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c33420 f091c002d597741e54934cfc76b16b5e 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 5.1E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c33420 f091c002d597741e54934cfc76b16b5e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 2.2E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c33420 f091c002d597741e54934cfc76b16b5e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 2.2E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c33420 f091c002d597741e54934cfc76b16b5e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 2.2E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c33420 f091c002d597741e54934cfc76b16b5e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 2.2E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c33420 f091c002d597741e54934cfc76b16b5e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 2.2E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c33420 f091c002d597741e54934cfc76b16b5e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 2.2E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c11050 507f97ebe44236c80d127828b2399187 544 SUPERFAMILY SSF51294 204 292 9.81E-15 T 12-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MIM_c11050 507f97ebe44236c80d127828b2399187 544 Pfam PF13403 Hint domain 205 341 3.3E-43 T 12-10-2018 IPR028992 Hedgehog/Intein (Hint) domain MIM_c00530 155ac79563bebd1a14e038d4c602f22d 565 SUPERFAMILY SSF51905 2 563 1.32E-61 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c00530 155ac79563bebd1a14e038d4c602f22d 565 Gene3D G3DSA:3.50.50.60 498 558 8.2E-30 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c00530 155ac79563bebd1a14e038d4c602f22d 565 Gene3D G3DSA:3.30.410.40 475 497 8.2E-30 T 12-10-2018 MIM_c00530 155ac79563bebd1a14e038d4c602f22d 565 Gene3D G3DSA:3.30.410.40 158 423 7.2E-116 T 12-10-2018 MIM_c00530 155ac79563bebd1a14e038d4c602f22d 565 Gene3D G3DSA:3.50.50.60 5 394 7.2E-116 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c00530 155ac79563bebd1a14e038d4c602f22d 565 SUPERFAMILY SSF54373 297 503 9.42E-16 T 12-10-2018 MIM_c00530 155ac79563bebd1a14e038d4c602f22d 565 PIRSF PIRSF000137 1 359 4.9E-75 T 12-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c00530 155ac79563bebd1a14e038d4c602f22d 565 PIRSF PIRSF000137 354 564 7.8E-38 T 12-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c00530 155ac79563bebd1a14e038d4c602f22d 565 Pfam PF00732 GMC oxidoreductase 6 302 7.1E-56 T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c00530 155ac79563bebd1a14e038d4c602f22d 565 Pfam PF05199 GMC oxidoreductase 369 556 6.4E-32 T 12-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 MIM_c22140 bd4a250840f01786ee9fd1297af3b1b4 571 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 300 317 2.1E-33 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c22140 bd4a250840f01786ee9fd1297af3b1b4 571 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 432 445 2.1E-33 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c22140 bd4a250840f01786ee9fd1297af3b1b4 571 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 339 355 2.1E-33 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c22140 bd4a250840f01786ee9fd1297af3b1b4 571 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 406 421 2.1E-33 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c22140 bd4a250840f01786ee9fd1297af3b1b4 571 Gene3D G3DSA:3.20.20.140 134 571 1.1E-288 T 12-10-2018 MIM_c22140 bd4a250840f01786ee9fd1297af3b1b4 571 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 4 571 6.0E-286 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c22140 bd4a250840f01786ee9fd1297af3b1b4 571 ProSitePatterns PS00145 Urease active site. 322 338 - T 12-10-2018 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c22140 bd4a250840f01786ee9fd1297af3b1b4 571 ProSitePatterns PS01120 Urease nickel ligands signature. 132 145 - T 12-10-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c22140 bd4a250840f01786ee9fd1297af3b1b4 571 SUPERFAMILY SSF51338 427 482 4.32E-6 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MIM_c22140 bd4a250840f01786ee9fd1297af3b1b4 571 Pfam PF01979 Amidohydrolase family 130 459 9.0E-75 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MIM_c22140 bd4a250840f01786ee9fd1297af3b1b4 571 SUPERFAMILY SSF51556 134 571 4.44E-197 T 12-10-2018 IPR032466 Metal-dependent hydrolase MIM_c22140 bd4a250840f01786ee9fd1297af3b1b4 571 Gene3D G3DSA:2.30.40.10 4 485 1.1E-288 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MIM_c22140 bd4a250840f01786ee9fd1297af3b1b4 571 Pfam PF00449 Urease alpha-subunit, N-terminal domain 3 124 2.6E-50 T 12-10-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c22140 bd4a250840f01786ee9fd1297af3b1b4 571 SUPERFAMILY SSF51338 2 183 2.73E-54 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MIM_c22140 bd4a250840f01786ee9fd1297af3b1b4 571 Hamap MF_01953 Urease subunit alpha [ureC]. 2 571 56.394 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c31390 087bad4b30e577745094aca9a4e4da50 401 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 380 1.7E-38 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MIM_c31390 087bad4b30e577745094aca9a4e4da50 401 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 217 2.7E-20 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MIM_c31390 087bad4b30e577745094aca9a4e4da50 401 Gene3D G3DSA:2.40.110.10 120 238 5.9E-27 T 12-10-2018 MIM_c31390 087bad4b30e577745094aca9a4e4da50 401 Gene3D G3DSA:1.10.540.10 1 113 1.2E-26 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c31390 087bad4b30e577745094aca9a4e4da50 401 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 5 106 2.5E-20 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c31390 087bad4b30e577745094aca9a4e4da50 401 SUPERFAMILY SSF47203 233 386 2.09E-43 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c31390 087bad4b30e577745094aca9a4e4da50 401 PIRSF PIRSF016578 2 383 4.1E-18 T 12-10-2018 MIM_c31390 087bad4b30e577745094aca9a4e4da50 401 SUPERFAMILY SSF56645 3 226 1.57E-50 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c31390 087bad4b30e577745094aca9a4e4da50 401 Gene3D G3DSA:1.20.140.10 239 394 8.6E-44 T 12-10-2018 MIM_c21250 3e83b1b4f9729fbba44a1705a13969b3 426 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 44 379 1.0E-86 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MIM_c21250 3e83b1b4f9729fbba44a1705a13969b3 426 Gene3D G3DSA:2.40.420.20 309 377 3.9E-107 T 12-10-2018 MIM_c21250 3e83b1b4f9729fbba44a1705a13969b3 426 Gene3D G3DSA:2.40.30.170 56 308 3.9E-107 T 12-10-2018 MIM_c21250 3e83b1b4f9729fbba44a1705a13969b3 426 Gene3D G3DSA:2.40.50.100 68 212 3.9E-107 T 12-10-2018 MIM_c21250 3e83b1b4f9729fbba44a1705a13969b3 426 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 68 298 1.6E-14 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MIM_c21250 3e83b1b4f9729fbba44a1705a13969b3 426 SUPERFAMILY SSF111369 56 305 2.22E-79 T 12-10-2018 MIM_c21250 3e83b1b4f9729fbba44a1705a13969b3 426 Gene3D G3DSA:1.10.287.470 103 176 3.9E-107 T 12-10-2018 MIM_c28330 1063242e72692eb446c89cfc8d7c900a 523 SUPERFAMILY SSF56024 105 297 9.73E-43 T 12-10-2018 MIM_c28330 1063242e72692eb446c89cfc8d7c900a 523 Gene3D G3DSA:3.30.870.10 330 522 4.2E-34 T 12-10-2018 MIM_c28330 1063242e72692eb446c89cfc8d7c900a 523 SUPERFAMILY SSF56024 333 500 3.14E-43 T 12-10-2018 MIM_c28330 1063242e72692eb446c89cfc8d7c900a 523 Pfam PF13091 PLD-like domain 368 492 3.7E-29 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MIM_c28330 1063242e72692eb446c89cfc8d7c900a 523 Pfam PF13091 PLD-like domain 145 286 8.0E-12 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MIM_c28330 1063242e72692eb446c89cfc8d7c900a 523 SMART SM00155 227 254 0.013 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MIM_c28330 1063242e72692eb446c89cfc8d7c900a 523 SMART SM00155 439 466 3.8E-8 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MIM_c28330 1063242e72692eb446c89cfc8d7c900a 523 Pfam PF13396 Phospholipase_D-nuclease N-terminal 34 72 2.6E-7 T 12-10-2018 IPR027379 Cardiolipin synthase N-terminal MIM_c28330 1063242e72692eb446c89cfc8d7c900a 523 PIRSF PIRSF000850 421 506 0.038 T 12-10-2018 MIM_c28330 1063242e72692eb446c89cfc8d7c900a 523 PIRSF PIRSF000850 358 426 1.2 T 12-10-2018 MIM_c28330 1063242e72692eb446c89cfc8d7c900a 523 PIRSF PIRSF000850 110 196 3.1 T 12-10-2018 MIM_c28330 1063242e72692eb446c89cfc8d7c900a 523 Gene3D G3DSA:3.30.870.10 127 324 4.2E-42 T 12-10-2018 MIM_c17110 a53ed8886efbce35d8e92bbd2913e621 653 SUPERFAMILY SSF55816 419 566 3.4E-22 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MIM_c17110 a53ed8886efbce35d8e92bbd2913e621 653 Pfam PF02872 5'-nucleotidase, C-terminal domain 442 564 3.1E-16 T 12-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MIM_c17110 a53ed8886efbce35d8e92bbd2913e621 653 Gene3D G3DSA:3.60.21.10 217 420 5.0E-33 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like MIM_c17110 a53ed8886efbce35d8e92bbd2913e621 653 SUPERFAMILY SSF56300 54 419 6.17E-27 T 12-10-2018 MIM_c17110 a53ed8886efbce35d8e92bbd2913e621 653 Gene3D G3DSA:3.90.780.10 422 587 3.1E-47 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MIM_c14980 197788e7a5b8eed534f8058bba87d6c6 564 Gene3D G3DSA:3.50.50.60 7 300 8.8E-22 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c14980 197788e7a5b8eed534f8058bba87d6c6 564 SUPERFAMILY SSF51905 9 548 2.59E-51 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c14980 197788e7a5b8eed534f8058bba87d6c6 564 Pfam PF01593 Flavin containing amine oxidoreductase 21 285 2.0E-18 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 MIM_c14980 197788e7a5b8eed534f8058bba87d6c6 564 Pfam PF01593 Flavin containing amine oxidoreductase 449 548 6.0E-9 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 MIM_c14980 197788e7a5b8eed534f8058bba87d6c6 564 PRINTS PR00419 Adrenodoxin reductase family signature 35 48 6.1E-6 T 12-10-2018 MIM_c14980 197788e7a5b8eed534f8058bba87d6c6 564 PRINTS PR00419 Adrenodoxin reductase family signature 12 34 6.1E-6 T 12-10-2018 MIM_c06800 68385f42a3052d73c07cb88572830112 344 SUPERFAMILY SSF51735 1 337 1.96E-99 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c06800 68385f42a3052d73c07cb88572830112 344 Gene3D G3DSA:3.90.25.10 194 329 5.9E-142 T 12-10-2018 MIM_c06800 68385f42a3052d73c07cb88572830112 344 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 335 1.3E-143 T 12-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 MIM_c06800 68385f42a3052d73c07cb88572830112 344 Gene3D G3DSA:3.40.50.720 4 274 5.9E-142 T 12-10-2018 MIM_c06800 68385f42a3052d73c07cb88572830112 344 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 262 5.1E-59 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MIM_c33220 ab665e023b984f9a09b8113bdaa9a561 637 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 35 191 1.0E-11 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c33220 ab665e023b984f9a09b8113bdaa9a561 637 Gene3D G3DSA:3.30.230.80 241 408 7.6E-69 T 12-10-2018 MIM_c33220 ab665e023b984f9a09b8113bdaa9a561 637 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 33 42 - T 12-10-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0051082 MIM_c33220 ab665e023b984f9a09b8113bdaa9a561 637 Gene3D G3DSA:3.40.50.11260 409 498 1.0E-32 T 12-10-2018 MIM_c33220 ab665e023b984f9a09b8113bdaa9a561 637 Gene3D G3DSA:3.30.565.10 1 235 5.1E-75 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c33220 ab665e023b984f9a09b8113bdaa9a561 637 Pfam PF00183 Hsp90 protein 222 635 6.8E-130 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 MIM_c33220 ab665e023b984f9a09b8113bdaa9a561 637 SUPERFAMILY SSF54211 242 497 1.29E-98 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MIM_c33220 ab665e023b984f9a09b8113bdaa9a561 637 PRINTS PR00775 90kDa heat shock protein signature 34 56 2.9E-61 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal MIM_c33220 ab665e023b984f9a09b8113bdaa9a561 637 PRINTS PR00775 90kDa heat shock protein signature 128 150 2.9E-61 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal MIM_c33220 ab665e023b984f9a09b8113bdaa9a561 637 PRINTS PR00775 90kDa heat shock protein signature 198 216 2.9E-61 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal MIM_c33220 ab665e023b984f9a09b8113bdaa9a561 637 PRINTS PR00775 90kDa heat shock protein signature 83 100 2.9E-61 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal MIM_c33220 ab665e023b984f9a09b8113bdaa9a561 637 PRINTS PR00775 90kDa heat shock protein signature 101 118 2.9E-61 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal MIM_c33220 ab665e023b984f9a09b8113bdaa9a561 637 PRINTS PR00775 90kDa heat shock protein signature 13 33 2.9E-61 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal MIM_c33220 ab665e023b984f9a09b8113bdaa9a561 637 PRINTS PR00775 90kDa heat shock protein signature 180 197 2.9E-61 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal MIM_c33220 ab665e023b984f9a09b8113bdaa9a561 637 SUPERFAMILY SSF110942 523 635 5.23E-35 T 12-10-2018 IPR037196 HSP90, C-terminal domain MIM_c33220 ab665e023b984f9a09b8113bdaa9a561 637 Hamap MF_00505 Chaperone protein HtpG [htpG]. 10 635 32.699 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 MIM_c33220 ab665e023b984f9a09b8113bdaa9a561 637 Gene3D G3DSA:1.20.120.790 503 636 3.1E-42 T 12-10-2018 IPR037196 HSP90, C-terminal domain MIM_c33220 ab665e023b984f9a09b8113bdaa9a561 637 SUPERFAMILY SSF55874 12 223 3.14E-66 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c33220 ab665e023b984f9a09b8113bdaa9a561 637 PIRSF PIRSF002583 1 637 5.7E-215 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 MIM_c33220 ab665e023b984f9a09b8113bdaa9a561 637 SMART SM00387 35 192 1.9E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c40880 b2e3fce0971c374576e1bebfc791b014 512 Gene3D G3DSA:3.40.190.10 187 500 6.5E-107 T 12-10-2018 MIM_c40880 b2e3fce0971c374576e1bebfc791b014 512 PIRSF PIRSF002741 18 510 1.0E-85 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MIM_c40880 b2e3fce0971c374576e1bebfc791b014 512 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 64 421 6.5E-77 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain MIM_c40880 b2e3fce0971c374576e1bebfc791b014 512 Gene3D G3DSA:3.90.76.10 40 186 6.5E-107 T 12-10-2018 MIM_c40880 b2e3fce0971c374576e1bebfc791b014 512 SUPERFAMILY SSF53850 22 510 1.49E-110 T 12-10-2018 MIM_c40880 b2e3fce0971c374576e1bebfc791b014 512 Gene3D G3DSA:3.10.105.10 279 488 6.5E-107 T 12-10-2018 MIM_c40880 b2e3fce0971c374576e1bebfc791b014 512 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 70 92 - T 12-10-2018 IPR023765 Solute-binding protein family 5, conserved site MIM_c11310 8849b488f368f73f465f1e358f77269b 260 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 2.2E-15 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MIM_c11310 8849b488f368f73f465f1e358f77269b 260 Pfam PF00455 DeoR C terminal sensor domain 82 238 9.4E-42 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain MIM_c11310 8849b488f368f73f465f1e358f77269b 260 SUPERFAMILY SSF46785 5 66 3.6E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c11310 8849b488f368f73f465f1e358f77269b 260 SMART SM01134 80 240 3.3E-49 T 12-10-2018 MIM_c11310 8849b488f368f73f465f1e358f77269b 260 Gene3D G3DSA:1.10.10.10 1 60 1.4E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c11310 8849b488f368f73f465f1e358f77269b 260 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 5.6E-9 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MIM_c11310 8849b488f368f73f465f1e358f77269b 260 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 5.6E-9 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MIM_c11310 8849b488f368f73f465f1e358f77269b 260 SMART SM00420 6 58 9.6E-14 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MIM_c11310 8849b488f368f73f465f1e358f77269b 260 SUPERFAMILY SSF100950 81 240 2.93E-23 T 12-10-2018 IPR037171 NagB/RpiA transferase-like MIM_c11310 8849b488f368f73f465f1e358f77269b 260 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 MIM_c11310 8849b488f368f73f465f1e358f77269b 260 Gene3D G3DSA:3.30.750.70 76 137 2.9E-5 T 12-10-2018 MIM_c15720 ab8e9147de7f05066fa4c090b30eb0a1 368 SMART SM00388 136 201 4.7E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MIM_c15720 ab8e9147de7f05066fa4c090b30eb0a1 368 PRINTS PR00344 Bacterial sensor protein C-terminal signature 315 333 4.0E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c15720 ab8e9147de7f05066fa4c090b30eb0a1 368 PRINTS PR00344 Bacterial sensor protein C-terminal signature 283 297 4.0E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c15720 ab8e9147de7f05066fa4c090b30eb0a1 368 PRINTS PR00344 Bacterial sensor protein C-terminal signature 301 311 4.0E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c15720 ab8e9147de7f05066fa4c090b30eb0a1 368 SUPERFAMILY SSF55874 191 353 1.83E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c15720 ab8e9147de7f05066fa4c090b30eb0a1 368 SMART SM00387 248 356 7.1E-29 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c15720 ab8e9147de7f05066fa4c090b30eb0a1 368 Pfam PF00512 His Kinase A (phospho-acceptor) domain 136 201 5.9E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MIM_c15720 ab8e9147de7f05066fa4c090b30eb0a1 368 Gene3D G3DSA:3.30.565.10 207 354 1.9E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c15720 ab8e9147de7f05066fa4c090b30eb0a1 368 SUPERFAMILY SSF47384 119 200 7.06E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MIM_c15720 ab8e9147de7f05066fa4c090b30eb0a1 368 Gene3D G3DSA:1.10.287.130 86 200 2.3E-15 T 12-10-2018 MIM_c15720 ab8e9147de7f05066fa4c090b30eb0a1 368 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 248 353 3.0E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c40420 09126dd36ad3d349a23651340571aee3 144 SUPERFAMILY SSF54637 8 140 2.92E-32 T 12-10-2018 IPR029069 HotDog domain superfamily MIM_c40420 09126dd36ad3d349a23651340571aee3 144 Gene3D G3DSA:3.10.129.10 8 143 1.4E-28 T 12-10-2018 MIM_c40420 09126dd36ad3d349a23651340571aee3 144 Pfam PF13279 Thioesterase-like superfamily 19 121 5.4E-8 T 12-10-2018 MIM_c40420 09126dd36ad3d349a23651340571aee3 144 PIRSF PIRSF003230 2 144 2.4E-20 T 12-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 MIM_c25730 e597a24aca81c46b4dfc69968ba74e0a 300 Gene3D G3DSA:3.40.50.1980 190 296 5.0E-18 T 12-10-2018 MIM_c25730 e597a24aca81c46b4dfc69968ba74e0a 300 SUPERFAMILY SSF53807 8 296 1.62E-65 T 12-10-2018 MIM_c25730 e597a24aca81c46b4dfc69968ba74e0a 300 Pfam PF01297 Zinc-uptake complex component A periplasmic 26 274 6.1E-51 T 12-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 MIM_c25730 e597a24aca81c46b4dfc69968ba74e0a 300 PRINTS PR00691 Adhesin B signature 20 41 1.4E-10 T 12-10-2018 IPR006129 Adhesin B GO:0007155 MIM_c25730 e597a24aca81c46b4dfc69968ba74e0a 300 PRINTS PR00691 Adhesin B signature 64 83 1.4E-10 T 12-10-2018 IPR006129 Adhesin B GO:0007155 MIM_c25730 e597a24aca81c46b4dfc69968ba74e0a 300 PRINTS PR00691 Adhesin B signature 127 146 1.4E-10 T 12-10-2018 IPR006129 Adhesin B GO:0007155 MIM_c25730 e597a24aca81c46b4dfc69968ba74e0a 300 PRINTS PR00691 Adhesin B signature 185 202 1.4E-10 T 12-10-2018 IPR006129 Adhesin B GO:0007155 MIM_c25730 e597a24aca81c46b4dfc69968ba74e0a 300 PRINTS PR00691 Adhesin B signature 45 63 1.4E-10 T 12-10-2018 IPR006129 Adhesin B GO:0007155 MIM_c25730 e597a24aca81c46b4dfc69968ba74e0a 300 PRINTS PR00690 Adhesin family signature 51 64 8.0E-10 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 MIM_c25730 e597a24aca81c46b4dfc69968ba74e0a 300 PRINTS PR00690 Adhesin family signature 64 81 8.0E-10 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 MIM_c25730 e597a24aca81c46b4dfc69968ba74e0a 300 PRINTS PR00690 Adhesin family signature 185 206 8.0E-10 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 MIM_c25730 e597a24aca81c46b4dfc69968ba74e0a 300 PRINTS PR00690 Adhesin family signature 238 256 8.0E-10 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 MIM_c25730 e597a24aca81c46b4dfc69968ba74e0a 300 Gene3D G3DSA:3.40.50.1980 13 185 7.5E-37 T 12-10-2018 MIM_c32130 964f4e1b0bdeee96ab214dadf41d4c8d 382 Gene3D G3DSA:3.90.870.10 7 217 1.4E-86 T 12-10-2018 MIM_c32130 964f4e1b0bdeee96ab214dadf41d4c8d 382 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 13 215 38.115 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MIM_c32130 964f4e1b0bdeee96ab214dadf41d4c8d 382 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 20 210 8.0E-81 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MIM_c32130 964f4e1b0bdeee96ab214dadf41d4c8d 382 PIRSF PIRSF001259 14 380 8.6E-115 T 12-10-2018 MIM_c32130 964f4e1b0bdeee96ab214dadf41d4c8d 382 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 16 211 1.6E-72 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MIM_c32130 964f4e1b0bdeee96ab214dadf41d4c8d 382 SUPERFAMILY SSF142695 216 376 1.03E-40 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MIM_c32130 964f4e1b0bdeee96ab214dadf41d4c8d 382 Gene3D G3DSA:3.40.50.10990 218 378 5.5E-24 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MIM_c32130 964f4e1b0bdeee96ab214dadf41d4c8d 382 SUPERFAMILY SSF55821 13 214 2.06E-84 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily MIM_c32130 964f4e1b0bdeee96ab214dadf41d4c8d 382 Pfam PF00925 GTP cyclohydrolase II 223 375 2.6E-33 T 12-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MIM_c21430 4e3921e275a412ce9b349f3076f9bd4d 251 Pfam PF01975 Survival protein SurE 4 183 2.8E-58 T 12-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 MIM_c21430 4e3921e275a412ce9b349f3076f9bd4d 251 Gene3D G3DSA:3.40.1210.10 1 250 2.1E-88 T 12-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 MIM_c21430 4e3921e275a412ce9b349f3076f9bd4d 251 SUPERFAMILY SSF64167 3 246 5.62E-81 T 12-10-2018 MIM_c21430 4e3921e275a412ce9b349f3076f9bd4d 251 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 3 234 8.9E-63 T 12-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 MIM_c21430 4e3921e275a412ce9b349f3076f9bd4d 251 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 2 251 37.77 T 12-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 SUPERFAMILY SSF69255 375 463 2.88E-32 T 12-10-2018 MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 Pfam PF03527 RHS protein 1709 1744 3.6E-15 T 12-10-2018 IPR001826 RHS protein MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 Pfam PF05954 Phage late control gene D protein (GPD) 34 336 8.0E-83 T 12-10-2018 MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 Gene3D G3DSA:3.55.50.10 104 194 1.1E-97 T 12-10-2018 MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 PRINTS PR00394 RHS protein signature 1756 1776 6.6E-16 T 12-10-2018 IPR001826 RHS protein MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 PRINTS PR00394 RHS protein signature 1702 1722 6.6E-16 T 12-10-2018 IPR001826 RHS protein MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 PRINTS PR00394 RHS protein signature 1779 1798 6.6E-16 T 12-10-2018 IPR001826 RHS protein MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 Pfam PF05593 RHS Repeat 1058 1093 2.2E-7 T 12-10-2018 IPR031325 RHS repeat MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 Pfam PF05593 RHS Repeat 1140 1176 1.0E-10 T 12-10-2018 IPR031325 RHS repeat MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 Pfam PF05593 RHS Repeat 1245 1281 5.0E-7 T 12-10-2018 IPR031325 RHS repeat MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 Pfam PF05593 RHS Repeat 1099 1131 5.3E-6 T 12-10-2018 IPR031325 RHS repeat MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 SUPERFAMILY SSF69279 193 375 2.72E-30 T 12-10-2018 MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 30 517 1.1E-134 T 12-10-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 SUPERFAMILY SSF69349 453 624 1.26E-32 T 12-10-2018 MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1161 1190 1.0E-5 T 12-10-2018 IPR006530 YD repeat MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1287 1329 4.7E-4 T 12-10-2018 IPR006530 YD repeat MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1245 1285 1.4E-7 T 12-10-2018 IPR006530 YD repeat MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1078 1119 7.7E-12 T 12-10-2018 IPR006530 YD repeat MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1203 1237 1.8E-4 T 12-10-2018 IPR006530 YD repeat MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1620 1654 3.0E-8 T 12-10-2018 IPR006530 YD repeat MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1121 1159 2.5E-6 T 12-10-2018 IPR006530 YD repeat MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 Gene3D G3DSA:3.30.1920.30 230 292 1.1E-97 T 12-10-2018 MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 Gene3D G3DSA:3.90.930.1 1232 1381 3.8E-13 T 12-10-2018 MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 Gene3D G3DSA:3.90.930.1 1065 1192 3.5E-13 T 12-10-2018 MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 Gene3D G3DSA:2.40.50.230 366 467 1.8E-41 T 12-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 Gene3D G3DSA:2.30.110.50 26 338 1.1E-97 T 12-10-2018 MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1736 1812 8.6E-27 T 12-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 SUPERFAMILY SSF69279 17 189 7.23E-49 T 12-10-2018 MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 14 535 3.9E-173 T 12-10-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset MIM_c33390 453119d18ab540b1c43d670b1f7b8750 1965 Gene3D G3DSA:2.180.10.10 1472 1812 4.9E-38 T 12-10-2018 MIM_c02560 93f0edddb73b179b3d0099fb35dcd9f8 363 SMART SM01329 5 349 1.1E-161 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MIM_c02560 93f0edddb73b179b3d0099fb35dcd9f8 363 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 349 1.7E-83 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MIM_c02560 93f0edddb73b179b3d0099fb35dcd9f8 363 Gene3D G3DSA:3.40.718.10 1 357 1.6E-127 T 12-10-2018 MIM_c02560 93f0edddb73b179b3d0099fb35dcd9f8 363 SUPERFAMILY SSF53659 2 353 1.32E-111 T 12-10-2018 MIM_c02560 93f0edddb73b179b3d0099fb35dcd9f8 363 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 1 353 6.6E-166 T 12-10-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 MIM_c02560 93f0edddb73b179b3d0099fb35dcd9f8 363 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 242 261 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 MIM_c25960 6a8fb54f0ff0f722011290aca93cdcba 505 TIGRFAM TIGR03706 exo_poly_only: exopolyphosphatase 15 313 2.0E-93 T 12-10-2018 IPR022371 Exopolyphosphatase GO:0004309|GO:0006793 MIM_c25960 6a8fb54f0ff0f722011290aca93cdcba 505 PIRSF PIRSF001267 6 504 3.7E-181 T 12-10-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 MIM_c25960 6a8fb54f0ff0f722011290aca93cdcba 505 SUPERFAMILY SSF53067 145 316 9.39E-40 T 12-10-2018 MIM_c25960 6a8fb54f0ff0f722011290aca93cdcba 505 Pfam PF02541 Ppx/GppA phosphatase family 33 314 1.7E-72 T 12-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 MIM_c25960 6a8fb54f0ff0f722011290aca93cdcba 505 Gene3D G3DSA:3.30.420.40 16 310 2.8E-82 T 12-10-2018 MIM_c25960 6a8fb54f0ff0f722011290aca93cdcba 505 SUPERFAMILY SSF53067 15 140 9.62E-35 T 12-10-2018 MIM_c25960 6a8fb54f0ff0f722011290aca93cdcba 505 SUPERFAMILY SSF109604 320 503 6.28E-39 T 12-10-2018 MIM_c25960 6a8fb54f0ff0f722011290aca93cdcba 505 Gene3D G3DSA:1.10.3210.10 317 504 4.7E-51 T 12-10-2018 MIM_c25960 6a8fb54f0ff0f722011290aca93cdcba 505 Gene3D G3DSA:3.30.420.150 123 302 2.8E-82 T 12-10-2018 MIM_c08630 7bc20780a0a81d29d0baf7bbb5b883ad 463 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 116 2.9E-8 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MIM_c08630 7bc20780a0a81d29d0baf7bbb5b883ad 463 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 295 313 2.9E-8 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MIM_c08630 7bc20780a0a81d29d0baf7bbb5b883ad 463 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 2.9E-8 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MIM_c08630 7bc20780a0a81d29d0baf7bbb5b883ad 463 Gene3D G3DSA:3.50.50.60 7 316 1.2E-33 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c08630 7bc20780a0a81d29d0baf7bbb5b883ad 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 5.6E-12 T 12-10-2018 MIM_c08630 7bc20780a0a81d29d0baf7bbb5b883ad 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 252 268 5.6E-12 T 12-10-2018 MIM_c08630 7bc20780a0a81d29d0baf7bbb5b883ad 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 5.6E-12 T 12-10-2018 MIM_c08630 7bc20780a0a81d29d0baf7bbb5b883ad 463 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 318 1.5E-18 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MIM_c08630 7bc20780a0a81d29d0baf7bbb5b883ad 463 Pfam PF04324 BFD-like [2Fe-2S] binding domain 377 428 2.4E-9 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain MIM_c08630 7bc20780a0a81d29d0baf7bbb5b883ad 463 Gene3D G3DSA:1.10.10.1100 366 438 6.7E-21 T 12-10-2018 MIM_c08630 7bc20780a0a81d29d0baf7bbb5b883ad 463 Gene3D G3DSA:3.50.50.60 119 260 1.2E-33 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c08630 7bc20780a0a81d29d0baf7bbb5b883ad 463 PIRSF PIRSF037495 1 463 4.4E-151 T 12-10-2018 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 MIM_c08630 7bc20780a0a81d29d0baf7bbb5b883ad 463 SUPERFAMILY SSF51905 1 331 3.09E-34 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c31570 40f75d094c8835222587933990d81170 344 PIRSF PIRSF500176 11 343 7.2E-68 T 12-10-2018 MIM_c31570 40f75d094c8835222587933990d81170 344 Gene3D G3DSA:3.40.50.40 233 342 5.0E-27 T 12-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 MIM_c31570 40f75d094c8835222587933990d81170 344 PIRSF PIRSF001220 9 343 2.8E-66 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c31570 40f75d094c8835222587933990d81170 344 Pfam PF00710 Asparaginase, N-terminal 14 208 4.1E-47 T 12-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 MIM_c31570 40f75d094c8835222587933990d81170 344 PRINTS PR00139 Asparaginase/glutaminase family signature 101 119 1.6E-14 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c31570 40f75d094c8835222587933990d81170 344 PRINTS PR00139 Asparaginase/glutaminase family signature 15 26 1.6E-14 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c31570 40f75d094c8835222587933990d81170 344 PRINTS PR00139 Asparaginase/glutaminase family signature 280 298 1.6E-14 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c31570 40f75d094c8835222587933990d81170 344 SMART SM00870 14 338 1.1E-87 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c31570 40f75d094c8835222587933990d81170 344 Gene3D G3DSA:3.40.50.1170 13 231 3.7E-63 T 12-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 MIM_c31570 40f75d094c8835222587933990d81170 344 SUPERFAMILY SSF53774 9 341 5.76E-80 T 12-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 MIM_24p00020 0e4ae3e1f482dd053bf9e3d26c01e61e 423 SUPERFAMILY SSF56672 2 236 2.85E-64 T 12-10-2018 MIM_24p00020 0e4ae3e1f482dd053bf9e3d26c01e61e 423 Pfam PF13438 Domain of unknown function (DUF4113) 370 420 2.1E-18 T 12-10-2018 IPR025188 Domain of unknown function DUF4113 MIM_24p00020 0e4ae3e1f482dd053bf9e3d26c01e61e 423 Gene3D G3DSA:3.30.70.270 6 153 5.3E-40 T 12-10-2018 MIM_24p00020 0e4ae3e1f482dd053bf9e3d26c01e61e 423 Pfam PF11798 IMS family HHH motif 172 199 6.3E-6 T 12-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 MIM_24p00020 0e4ae3e1f482dd053bf9e3d26c01e61e 423 Gene3D G3DSA:1.10.150.20 169 237 4.6E-10 T 12-10-2018 MIM_24p00020 0e4ae3e1f482dd053bf9e3d26c01e61e 423 Gene3D G3DSA:2.30.40.20 11 73 5.3E-40 T 12-10-2018 MIM_24p00020 0e4ae3e1f482dd053bf9e3d26c01e61e 423 Pfam PF11799 impB/mucB/samB family C-terminal domain 242 352 2.7E-11 T 12-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MIM_24p00020 0e4ae3e1f482dd053bf9e3d26c01e61e 423 Pfam PF00817 impB/mucB/samB family 6 148 2.7E-34 T 12-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MIM_c37360 1ae3ebd7db893ae0e21824f181227594 506 Gene3D G3DSA:3.40.309.10 258 459 1.9E-153 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MIM_c37360 1ae3ebd7db893ae0e21824f181227594 506 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 14 490 1.2E-202 T 12-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 MIM_c37360 1ae3ebd7db893ae0e21824f181227594 506 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 283 294 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MIM_c37360 1ae3ebd7db893ae0e21824f181227594 506 SUPERFAMILY SSF53720 15 492 1.44E-149 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c37360 1ae3ebd7db893ae0e21824f181227594 506 Gene3D G3DSA:3.40.605.10 32 467 1.9E-153 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c37360 1ae3ebd7db893ae0e21824f181227594 506 Pfam PF00171 Aldehyde dehydrogenase family 24 486 1.0E-144 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c01490 84ff9214cb09e260a14a5b4b5c05e71a 373 Gene3D G3DSA:3.20.20.30 1 360 4.2E-142 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MIM_c01490 84ff9214cb09e260a14a5b4b5c05e71a 373 Pfam PF00296 Luciferase-like monooxygenase 4 325 1.7E-87 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MIM_c01490 84ff9214cb09e260a14a5b4b5c05e71a 373 TIGRFAM TIGR03565 alk_sulf_monoox: alkanesulfonate monooxygenase, FMNH(2)-dependent 4 349 1.9E-176 T 12-10-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 MIM_c01490 84ff9214cb09e260a14a5b4b5c05e71a 373 SUPERFAMILY SSF51679 3 352 5.63E-101 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MIM_c01490 84ff9214cb09e260a14a5b4b5c05e71a 373 Hamap MF_01229 Alkanesulfonate monooxygenase [ssuD]. 3 370 72.202 T 12-10-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 MIM_c35660 25df4f84895c2300ee4c9f9ff4533f65 662 Pfam PF05954 Phage late control gene D protein (GPD) 31 330 1.4E-96 T 12-10-2018 MIM_c35660 25df4f84895c2300ee4c9f9ff4533f65 662 SUPERFAMILY SSF69349 445 638 1.1E-19 T 12-10-2018 MIM_c35660 25df4f84895c2300ee4c9f9ff4533f65 662 SUPERFAMILY SSF69279 190 365 1.02E-42 T 12-10-2018 MIM_c35660 25df4f84895c2300ee4c9f9ff4533f65 662 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 21 521 1.5E-176 T 12-10-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset MIM_c35660 25df4f84895c2300ee4c9f9ff4533f65 662 Gene3D G3DSA:2.40.50.230 357 459 7.9E-43 T 12-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily MIM_c35660 25df4f84895c2300ee4c9f9ff4533f65 662 SUPERFAMILY SSF69255 367 454 2.62E-33 T 12-10-2018 MIM_c35660 25df4f84895c2300ee4c9f9ff4533f65 662 Gene3D G3DSA:2.30.110.50 16 333 1.4E-116 T 12-10-2018 MIM_c35660 25df4f84895c2300ee4c9f9ff4533f65 662 Gene3D G3DSA:3.55.50.10 101 191 1.4E-116 T 12-10-2018 MIM_c35660 25df4f84895c2300ee4c9f9ff4533f65 662 SUPERFAMILY SSF69279 22 187 2.21E-56 T 12-10-2018 MIM_c35660 25df4f84895c2300ee4c9f9ff4533f65 662 Gene3D G3DSA:3.30.1920.30 227 289 1.4E-116 T 12-10-2018 MIM_c35660 25df4f84895c2300ee4c9f9ff4533f65 662 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 26 505 8.8E-145 T 12-10-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein MIM_c27140 c4ae78839e11538d221a367763f3f3c9 301 SUPERFAMILY SSF46785 2 85 4.83E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c27140 c4ae78839e11538d221a367763f3f3c9 301 Pfam PF03466 LysR substrate binding domain 90 290 1.6E-30 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c27140 c4ae78839e11538d221a367763f3f3c9 301 Gene3D G3DSA:1.10.10.10 7 90 1.1E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c27140 c4ae78839e11538d221a367763f3f3c9 301 Gene3D G3DSA:3.40.190.10 103 286 3.3E-39 T 12-10-2018 MIM_c27140 c4ae78839e11538d221a367763f3f3c9 301 SUPERFAMILY SSF53850 92 293 3.8E-33 T 12-10-2018 MIM_c27140 c4ae78839e11538d221a367763f3f3c9 301 Gene3D G3DSA:3.40.190.10 163 262 3.3E-39 T 12-10-2018 MIM_c27140 c4ae78839e11538d221a367763f3f3c9 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 3.6E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c27140 c4ae78839e11538d221a367763f3f3c9 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.6E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c27140 c4ae78839e11538d221a367763f3f3c9 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.6E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c27140 c4ae78839e11538d221a367763f3f3c9 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.6E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c39680 d92c0c5e27c0996c271c3a4ab69f1ade 275 SMART SM01383 42 118 1.4E-41 T 12-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c39680 d92c0c5e27c0996c271c3a4ab69f1ade 275 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 45.723 T 12-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 MIM_c39680 d92c0c5e27c0996c271c3a4ab69f1ade 275 PIRSF PIRSF002158 7 275 1.3E-99 T 12-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c39680 d92c0c5e27c0996c271c3a4ab69f1ade 275 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 4 273 1.6E-125 T 12-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 MIM_c39680 d92c0c5e27c0996c271c3a4ab69f1ade 275 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 116 3.6E-32 T 12-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c39680 d92c0c5e27c0996c271c3a4ab69f1ade 275 Gene3D G3DSA:2.30.30.30 118 196 1.8E-31 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 MIM_c39680 d92c0c5e27c0996c271c3a4ab69f1ade 275 Gene3D G3DSA:4.10.950.10 197 274 3.4E-34 T 12-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39680 d92c0c5e27c0996c271c3a4ab69f1ade 275 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 12-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39680 d92c0c5e27c0996c271c3a4ab69f1ade 275 Gene3D G3DSA:2.40.50.140 1 114 1.4E-46 T 12-10-2018 MIM_c39680 d92c0c5e27c0996c271c3a4ab69f1ade 275 SMART SM01382 124 252 1.2E-87 T 12-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 MIM_c39680 d92c0c5e27c0996c271c3a4ab69f1ade 275 SUPERFAMILY SSF50104 126 272 7.22E-60 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily MIM_c39680 d92c0c5e27c0996c271c3a4ab69f1ade 275 SUPERFAMILY SSF50249 3 124 3.43E-46 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c39680 d92c0c5e27c0996c271c3a4ab69f1ade 275 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 250 1.4E-55 T 12-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 MIM_c30820 f9031e77a8ff587648fecbe06142b818 334 SUPERFAMILY SSF81345 5 329 1.2E-74 T 12-10-2018 IPR037294 ABC transporter, BtuC-like MIM_c30820 f9031e77a8ff587648fecbe06142b818 334 Pfam PF01032 FecCD transport family 20 329 3.1E-86 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MIM_c30820 f9031e77a8ff587648fecbe06142b818 334 Gene3D G3DSA:1.10.3470.10 7 333 2.1E-86 T 12-10-2018 IPR037294 ABC transporter, BtuC-like MIM_c26000 95b144be95516528d0bd0999a7bafe94 636 Gene3D G3DSA:3.40.50.300 143 324 9.1E-70 T 12-10-2018 MIM_c26000 95b144be95516528d0bd0999a7bafe94 636 Pfam PF06480 FtsH Extracellular 11 77 3.8E-7 T 12-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 MIM_c26000 95b144be95516528d0bd0999a7bafe94 636 Gene3D G3DSA:2.40.50.920 30 104 6.0E-8 T 12-10-2018 MIM_c26000 95b144be95516528d0bd0999a7bafe94 636 SUPERFAMILY SSF140990 406 604 4.32E-74 T 12-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 MIM_c26000 95b144be95516528d0bd0999a7bafe94 636 SUPERFAMILY SSF52540 148 395 3.01E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c26000 95b144be95516528d0bd0999a7bafe94 636 Pfam PF01434 Peptidase family M41 386 593 3.2E-79 T 12-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 MIM_c26000 95b144be95516528d0bd0999a7bafe94 636 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 7 613 37.298 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 MIM_c26000 95b144be95516528d0bd0999a7bafe94 636 ProSitePatterns PS00674 AAA-protein family signature. 295 313 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 MIM_c26000 95b144be95516528d0bd0999a7bafe94 636 Gene3D G3DSA:1.10.8.60 326 403 7.9E-29 T 12-10-2018 MIM_c26000 95b144be95516528d0bd0999a7bafe94 636 Gene3D G3DSA:1.20.58.760 406 603 1.5E-71 T 12-10-2018 MIM_c26000 95b144be95516528d0bd0999a7bafe94 636 SMART SM00382 188 327 2.8E-26 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c26000 95b144be95516528d0bd0999a7bafe94 636 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 192 324 1.2E-46 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MIM_c26000 95b144be95516528d0bd0999a7bafe94 636 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 103 595 9.3E-240 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 MIM_c19860 7c82e490ee6be2d02814a363f1e1b68b 655 Pfam PF14518 Iron-containing redox enzyme 530 643 9.3E-9 T 12-10-2018 MIM_c19860 7c82e490ee6be2d02814a363f1e1b68b 655 SUPERFAMILY SSF53901 6 202 6.72E-27 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c19860 7c82e490ee6be2d02814a363f1e1b68b 655 SUPERFAMILY SSF48613 436 648 3.02E-27 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 MIM_c19860 7c82e490ee6be2d02814a363f1e1b68b 655 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 285 359 6.4E-8 T 12-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MIM_c19860 7c82e490ee6be2d02814a363f1e1b68b 655 Gene3D G3DSA:3.40.47.10 8 202 8.6E-36 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c19860 7c82e490ee6be2d02814a363f1e1b68b 655 SUPERFAMILY SSF53901 253 369 3.31E-14 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c19860 7c82e490ee6be2d02814a363f1e1b68b 655 Gene3D G3DSA:1.20.910.10 436 655 4.8E-41 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 MIM_c19860 7c82e490ee6be2d02814a363f1e1b68b 655 Gene3D G3DSA:3.40.47.10 230 375 3.4E-25 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c05450 45db1e6997b409262142922c108b5061 300 TIGRFAM TIGR00761 argB: acetylglutamate kinase 34 275 6.4E-74 T 12-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MIM_c05450 45db1e6997b409262142922c108b5061 300 SUPERFAMILY SSF53633 16 299 5.76E-86 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MIM_c05450 45db1e6997b409262142922c108b5061 300 Pfam PF00696 Amino acid kinase family 33 277 1.6E-44 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 MIM_c05450 45db1e6997b409262142922c108b5061 300 Hamap MF_00082 Acetylglutamate kinase [argB]. 32 293 47.965 T 12-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MIM_c05450 45db1e6997b409262142922c108b5061 300 Gene3D G3DSA:3.40.1160.10 9 300 2.6E-95 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MIM_c05450 45db1e6997b409262142922c108b5061 300 PIRSF PIRSF000728 18 300 5.2E-102 T 12-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MIM_c05450 45db1e6997b409262142922c108b5061 300 PRINTS PR00474 Glutamate 5-kinase family signature 200 227 5.3E-5 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MIM_c05450 45db1e6997b409262142922c108b5061 300 PRINTS PR00474 Glutamate 5-kinase family signature 250 270 5.3E-5 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MIM_c07010 44f26466ff98ed3f94c792b3ec57ce6e 656 Gene3D G3DSA:3.40.50.12780 339 476 6.6E-35 T 12-10-2018 MIM_c07010 44f26466ff98ed3f94c792b3ec57ce6e 656 SUPERFAMILY SSF56801 11 612 2.35E-110 T 12-10-2018 MIM_c07010 44f26466ff98ed3f94c792b3ec57ce6e 656 Pfam PF00501 AMP-binding enzyme 21 477 2.5E-88 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MIM_c07010 44f26466ff98ed3f94c792b3ec57ce6e 656 ProSitePatterns PS00455 Putative AMP-binding domain signature. 195 206 - T 12-10-2018 IPR020845 AMP-binding, conserved site MIM_c07010 44f26466ff98ed3f94c792b3ec57ce6e 656 Gene3D G3DSA:3.40.50.12780 7 314 2.0E-52 T 12-10-2018 MIM_c05890 c86e34cb3d28065cfcd5aa4dcbd2c915 638 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 562 597 1.1E-8 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c05890 c86e34cb3d28065cfcd5aa4dcbd2c915 638 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 262 293 2.6E-5 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c05890 c86e34cb3d28065cfcd5aa4dcbd2c915 638 ProSitePatterns PS00211 ABC transporters family signature. 183 197 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c05890 c86e34cb3d28065cfcd5aa4dcbd2c915 638 SUPERFAMILY SSF52540 26 282 4.86E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c05890 c86e34cb3d28065cfcd5aa4dcbd2c915 638 Pfam PF00005 ABC transporter 360 509 1.6E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c05890 c86e34cb3d28065cfcd5aa4dcbd2c915 638 SUPERFAMILY SSF52540 332 582 5.11E-72 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c05890 c86e34cb3d28065cfcd5aa4dcbd2c915 638 SMART SM00382 368 560 4.8E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c05890 c86e34cb3d28065cfcd5aa4dcbd2c915 638 SMART SM00382 55 260 3.6E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c05890 c86e34cb3d28065cfcd5aa4dcbd2c915 638 Pfam PF00005 ABC transporter 47 210 2.7E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c05890 c86e34cb3d28065cfcd5aa4dcbd2c915 638 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 560 610 9.4E-12 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c05890 c86e34cb3d28065cfcd5aa4dcbd2c915 638 Gene3D G3DSA:3.40.50.300 331 635 2.7E-86 T 12-10-2018 MIM_c05890 c86e34cb3d28065cfcd5aa4dcbd2c915 638 Gene3D G3DSA:3.40.50.300 24 330 2.1E-82 T 12-10-2018 MIM_c05890 c86e34cb3d28065cfcd5aa4dcbd2c915 638 ProSitePatterns PS00211 ABC transporters family signature. 483 497 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c21710 1c441bbb74d87b8b0c6940de6fe9ee6e 388 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 273 279 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MIM_c21710 1c441bbb74d87b8b0c6940de6fe9ee6e 388 Pfam PF05175 Methyltransferase small domain 177 324 5.4E-18 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 MIM_c21710 1c441bbb74d87b8b0c6940de6fe9ee6e 388 SUPERFAMILY SSF53335 148 352 1.15E-29 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c21710 1c441bbb74d87b8b0c6940de6fe9ee6e 388 Gene3D G3DSA:3.40.50.150 166 358 9.4E-30 T 12-10-2018 MIM_c08460 76a2208c29a191cfcecb61998a021aee 274 Gene3D G3DSA:3.40.190.10 121 215 4.6E-58 T 12-10-2018 MIM_c08460 76a2208c29a191cfcecb61998a021aee 274 SMART SM00062 33 258 4.0E-52 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c08460 76a2208c29a191cfcecb61998a021aee 274 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 57 70 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site MIM_c08460 76a2208c29a191cfcecb61998a021aee 274 Gene3D G3DSA:3.40.190.10 23 256 4.6E-58 T 12-10-2018 MIM_c08460 76a2208c29a191cfcecb61998a021aee 274 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 34 256 3.1E-53 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c08460 76a2208c29a191cfcecb61998a021aee 274 SUPERFAMILY SSF53850 3 257 1.34E-57 T 12-10-2018 MIM_c09540 bccf080c56fd0061cbee5a874d80cbf8 255 SUPERFAMILY SSF51735 11 254 3.59E-81 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c09540 bccf080c56fd0061cbee5a874d80cbf8 255 Gene3D G3DSA:3.40.50.720 2 255 6.0E-81 T 12-10-2018 MIM_c09540 bccf080c56fd0061cbee5a874d80cbf8 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 191 3.0E-4 T 12-10-2018 MIM_c09540 bccf080c56fd0061cbee5a874d80cbf8 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 253 2.1E-61 T 12-10-2018 MIM_c09540 bccf080c56fd0061cbee5a874d80cbf8 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c09540 bccf080c56fd0061cbee5a874d80cbf8 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 2.6E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c09540 bccf080c56fd0061cbee5a874d80cbf8 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 2.6E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c09540 bccf080c56fd0061cbee5a874d80cbf8 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 2.6E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c09540 bccf080c56fd0061cbee5a874d80cbf8 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.5E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c09540 bccf080c56fd0061cbee5a874d80cbf8 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.5E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c09540 bccf080c56fd0061cbee5a874d80cbf8 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.5E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c09540 bccf080c56fd0061cbee5a874d80cbf8 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 1.5E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c09540 bccf080c56fd0061cbee5a874d80cbf8 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 1.5E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c09540 bccf080c56fd0061cbee5a874d80cbf8 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.5E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c16840 147f7743cd825bf068bda3109b4263b2 648 Gene3D G3DSA:3.40.50.300 8 278 1.3E-59 T 12-10-2018 MIM_c16840 147f7743cd825bf068bda3109b4263b2 648 Gene3D G3DSA:3.40.50.300 279 542 7.3E-51 T 12-10-2018 MIM_c16840 147f7743cd825bf068bda3109b4263b2 648 ProSitePatterns PS00211 ABC transporters family signature. 435 449 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c16840 147f7743cd825bf068bda3109b4263b2 648 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c16840 147f7743cd825bf068bda3109b4263b2 648 SUPERFAMILY SSF52540 296 520 9.55E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c16840 147f7743cd825bf068bda3109b4263b2 648 Pfam PF16326 ABC transporter C-terminal domain 572 636 4.1E-8 T 12-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 MIM_c16840 147f7743cd825bf068bda3109b4263b2 648 Pfam PF00005 ABC transporter 17 177 2.1E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c16840 147f7743cd825bf068bda3109b4263b2 648 Pfam PF00005 ABC transporter 332 463 1.2E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c16840 147f7743cd825bf068bda3109b4263b2 648 Pfam PF12848 ABC transporter 216 292 9.0E-24 T 12-10-2018 IPR032781 ABC-transporter extension domain MIM_c16840 147f7743cd825bf068bda3109b4263b2 648 SUPERFAMILY SSF52540 2 244 4.02E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c16840 147f7743cd825bf068bda3109b4263b2 648 SMART SM00382 341 508 1.3E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c16840 147f7743cd825bf068bda3109b4263b2 648 SMART SM00382 26 222 7.3E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c19670 e910512a29c0554b1932f4dbd51ef16b 231 Gene3D G3DSA:3.40.30.10 2 202 7.2E-83 T 12-10-2018 MIM_c19670 e910512a29c0554b1932f4dbd51ef16b 231 Pfam PF00043 Glutathione S-transferase, C-terminal domain 124 196 1.7E-9 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal MIM_c19670 e910512a29c0554b1932f4dbd51ef16b 231 SUPERFAMILY SSF47616 78 206 6.82E-36 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MIM_c19670 e910512a29c0554b1932f4dbd51ef16b 231 Pfam PF02798 Glutathione S-transferase, N-terminal domain 4 81 4.0E-14 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MIM_c19670 e910512a29c0554b1932f4dbd51ef16b 231 SUPERFAMILY SSF52833 1 84 4.75E-22 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c19670 e910512a29c0554b1932f4dbd51ef16b 231 Gene3D G3DSA:1.20.1050.10 88 195 7.2E-83 T 12-10-2018 MIM_c39410 0a2589b2f788e48e1a637a4e2b56188a 469 Pfam PF02913 FAD linked oxidases, C-terminal domain 224 464 9.5E-66 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 MIM_c39410 0a2589b2f788e48e1a637a4e2b56188a 469 SUPERFAMILY SSF56176 10 224 1.17E-70 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MIM_c39410 0a2589b2f788e48e1a637a4e2b56188a 469 Gene3D G3DSA:1.10.45.10 425 465 3.0E-13 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 MIM_c39410 0a2589b2f788e48e1a637a4e2b56188a 469 Pfam PF01565 FAD binding domain 50 187 4.4E-41 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MIM_c39410 0a2589b2f788e48e1a637a4e2b56188a 469 SUPERFAMILY SSF55103 228 468 1.28E-72 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MIM_c39410 0a2589b2f788e48e1a637a4e2b56188a 469 Gene3D G3DSA:3.30.70.2740 342 424 6.3E-13 T 12-10-2018 MIM_c39410 0a2589b2f788e48e1a637a4e2b56188a 469 Gene3D G3DSA:3.30.465.40 26 239 6.1E-72 T 12-10-2018 MIM_c26290 0fafdcb3dc6e182cd27832e9aa114e6e 442 Gene3D G3DSA:2.60.40.3500 35 153 4.7E-32 T 12-10-2018 MIM_c26290 0fafdcb3dc6e182cd27832e9aa114e6e 442 Gene3D G3DSA:3.40.630.40 199 442 1.5E-82 T 12-10-2018 MIM_c26290 0fafdcb3dc6e182cd27832e9aa114e6e 442 SMART SM00646 274 429 1.5E-60 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MIM_c26290 0fafdcb3dc6e182cd27832e9aa114e6e 442 SUPERFAMILY SSF53187 212 432 5.02E-55 T 12-10-2018 MIM_c26290 0fafdcb3dc6e182cd27832e9aa114e6e 442 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 214 429 1.3E-48 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MIM_c26290 0fafdcb3dc6e182cd27832e9aa114e6e 442 Pfam PF11741 AMIN domain 47 150 8.6E-24 T 12-10-2018 IPR021731 AMIN domain MIM_c08380 1727207be39a260a5f8d42176a741b9e 696 Pfam PF00199 Catalase 38 423 4.3E-178 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c08380 1727207be39a260a5f8d42176a741b9e 696 Gene3D G3DSA:1.20.1370.20 449 545 2.5E-29 T 12-10-2018 MIM_c08380 1727207be39a260a5f8d42176a741b9e 696 SUPERFAMILY SSF52317 550 670 6.56E-12 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c08380 1727207be39a260a5f8d42176a741b9e 696 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 368 376 - T 12-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c08380 1727207be39a260a5f8d42176a741b9e 696 PIRSF PIRSF038927 3 694 9.0E-293 T 12-10-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 MIM_c08380 1727207be39a260a5f8d42176a741b9e 696 SUPERFAMILY SSF56634 29 529 3.01E-215 T 12-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c08380 1727207be39a260a5f8d42176a741b9e 696 Pfam PF06628 Catalase-related immune-responsive 451 515 7.0E-21 T 12-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c08380 1727207be39a260a5f8d42176a741b9e 696 PRINTS PR00067 Catalase signature 114 132 2.2E-68 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c08380 1727207be39a260a5f8d42176a741b9e 696 PRINTS PR00067 Catalase signature 154 172 2.2E-68 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c08380 1727207be39a260a5f8d42176a741b9e 696 PRINTS PR00067 Catalase signature 323 350 2.2E-68 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c08380 1727207be39a260a5f8d42176a741b9e 696 PRINTS PR00067 Catalase signature 51 74 2.2E-68 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c08380 1727207be39a260a5f8d42176a741b9e 696 PRINTS PR00067 Catalase signature 135 152 2.2E-68 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c08380 1727207be39a260a5f8d42176a741b9e 696 PRINTS PR00067 Catalase signature 355 381 2.2E-68 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c08380 1727207be39a260a5f8d42176a741b9e 696 Gene3D G3DSA:2.40.180.10 1 446 2.1E-200 T 12-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 MIM_c08380 1727207be39a260a5f8d42176a741b9e 696 SMART SM01060 38 426 1.1E-269 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c08380 1727207be39a260a5f8d42176a741b9e 696 ProSitePatterns PS00438 Catalase proximal active site signature. 74 90 - T 12-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c08380 1727207be39a260a5f8d42176a741b9e 696 Gene3D G3DSA:3.40.50.880 546 693 7.8E-28 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c20180 0b08d4d3fed2a2bece2feb3405c88993 394 SUPERFAMILY SSF56645 20 251 6.54E-57 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c20180 0b08d4d3fed2a2bece2feb3405c88993 394 SUPERFAMILY SSF47203 237 392 1.1E-44 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c20180 0b08d4d3fed2a2bece2feb3405c88993 394 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 24 122 2.2E-19 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c20180 0b08d4d3fed2a2bece2feb3405c88993 394 Gene3D G3DSA:1.10.540.10 10 124 3.9E-22 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c20180 0b08d4d3fed2a2bece2feb3405c88993 394 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 346 365 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MIM_c20180 0b08d4d3fed2a2bece2feb3405c88993 394 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 210 9.3E-16 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MIM_c20180 0b08d4d3fed2a2bece2feb3405c88993 394 Gene3D G3DSA:1.20.140.10 243 393 1.4E-37 T 12-10-2018 MIM_c20180 0b08d4d3fed2a2bece2feb3405c88993 394 Gene3D G3DSA:2.40.110.10 127 242 2.4E-32 T 12-10-2018 MIM_c20180 0b08d4d3fed2a2bece2feb3405c88993 394 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 239 372 6.6E-34 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MIM_c40660 b278079070fcb321a7e1d1a98d0edf81 231 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 12-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c40660 b278079070fcb321a7e1d1a98d0edf81 231 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 227 9.5E-104 T 12-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 MIM_c40660 b278079070fcb321a7e1d1a98d0edf81 231 Gene3D G3DSA:3.30.190.20 25 221 2.4E-78 T 12-10-2018 MIM_c40660 b278079070fcb321a7e1d1a98d0edf81 231 Gene3D G3DSA:3.40.50.790 68 159 2.4E-78 T 12-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich MIM_c40660 b278079070fcb321a7e1d1a98d0edf81 231 SUPERFAMILY SSF56808 6 225 1.57E-81 T 12-10-2018 IPR023674 Ribosomal protein L1-like MIM_c40660 b278079070fcb321a7e1d1a98d0edf81 231 PIRSF PIRSF002155 1 227 2.9E-77 T 12-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c40660 b278079070fcb321a7e1d1a98d0edf81 231 Pfam PF00687 Ribosomal protein L1p/L10e family 31 219 7.6E-51 T 12-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein MIM_c40660 b278079070fcb321a7e1d1a98d0edf81 231 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 43.621 T 12-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 MIM_c28560 2c98f0ea9d7cc029da1cf88a86d9261e 315 Gene3D G3DSA:3.10.20.10 56 127 4.8E-9 T 12-10-2018 MIM_c28560 2c98f0ea9d7cc029da1cf88a86d9261e 315 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 28 315 31.824 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MIM_c28560 2c98f0ea9d7cc029da1cf88a86d9261e 315 SUPERFAMILY SSF53927 36 315 9.63E-73 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 MIM_c28560 2c98f0ea9d7cc029da1cf88a86d9261e 315 PIRSF PIRSF015626 161 315 9.2E-51 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MIM_c28560 2c98f0ea9d7cc029da1cf88a86d9261e 315 PIRSF PIRSF015626 19 164 1.9E-22 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MIM_c28560 2c98f0ea9d7cc029da1cf88a86d9261e 315 Gene3D G3DSA:3.40.140.10 172 315 1.2E-50 T 12-10-2018 MIM_c28560 2c98f0ea9d7cc029da1cf88a86d9261e 315 Pfam PF02634 FdhD/NarQ family 54 314 5.9E-71 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MIM_c22840 ec12ced2eed90a5ce0380fe7e4fff1ad 362 SMART SM00830 13 95 1.6E-23 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MIM_c22840 ec12ced2eed90a5ce0380fe7e4fff1ad 362 SUPERFAMILY SSF53850 96 279 2.61E-58 T 12-10-2018 MIM_c22840 ec12ced2eed90a5ce0380fe7e4fff1ad 362 PIRSF PIRSF001500 2 362 2.0E-137 T 12-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 MIM_c22840 ec12ced2eed90a5ce0380fe7e4fff1ad 362 Gene3D G3DSA:3.40.190.10 99 269 8.7E-57 T 12-10-2018 MIM_c22840 ec12ced2eed90a5ce0380fe7e4fff1ad 362 Pfam PF00800 Prephenate dehydratase 97 271 4.8E-60 T 12-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 MIM_c22840 ec12ced2eed90a5ce0380fe7e4fff1ad 362 TIGRFAM TIGR01807 CM_P2: chorismate mutase 9 85 9.9E-21 T 12-10-2018 IPR010957 Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626 MIM_c22840 ec12ced2eed90a5ce0380fe7e4fff1ad 362 Gene3D G3DSA:1.20.59.10 5 95 8.9E-23 T 12-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MIM_c22840 ec12ced2eed90a5ce0380fe7e4fff1ad 362 SUPERFAMILY SSF55021 266 361 5.34E-27 T 12-10-2018 MIM_c22840 ec12ced2eed90a5ce0380fe7e4fff1ad 362 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 309 316 - T 12-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 MIM_c22840 ec12ced2eed90a5ce0380fe7e4fff1ad 362 SUPERFAMILY SSF48600 8 99 7.88E-18 T 12-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MIM_c22840 ec12ced2eed90a5ce0380fe7e4fff1ad 362 Pfam PF01817 Chorismate mutase type II 13 93 1.9E-19 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MIM_c22840 ec12ced2eed90a5ce0380fe7e4fff1ad 362 Gene3D G3DSA:3.40.190.10 177 261 8.7E-57 T 12-10-2018 MIM_c22840 ec12ced2eed90a5ce0380fe7e4fff1ad 362 Gene3D G3DSA:3.30.70.260 275 362 9.1E-29 T 12-10-2018 MIM_c22840 ec12ced2eed90a5ce0380fe7e4fff1ad 362 Pfam PF01842 ACT domain 282 346 2.5E-8 T 12-10-2018 IPR002912 ACT domain MIM_c22010 1b2a7f4b67092197204677248b8b7238 435 Gene3D G3DSA:1.10.8.60 317 425 2.0E-37 T 12-10-2018 MIM_c22010 1b2a7f4b67092197204677248b8b7238 435 SUPERFAMILY SSF52540 64 401 3.71E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c22010 1b2a7f4b67092197204677248b8b7238 435 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 6 416 51.976 T 12-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 MIM_c22010 1b2a7f4b67092197204677248b8b7238 435 Gene3D G3DSA:3.30.50.30 2 52 2.1E-19 T 12-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily MIM_c22010 1b2a7f4b67092197204677248b8b7238 435 Pfam PF06689 ClpX C4-type zinc finger 13 50 1.1E-18 T 12-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 MIM_c22010 1b2a7f4b67092197204677248b8b7238 435 SMART SM00382 114 267 9.4E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c22010 1b2a7f4b67092197204677248b8b7238 435 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 412 5.6E-197 T 12-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 MIM_c22010 1b2a7f4b67092197204677248b8b7238 435 SMART SM00994 12 52 3.4E-19 T 12-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 MIM_c22010 1b2a7f4b67092197204677248b8b7238 435 SUPERFAMILY SSF57716 13 49 2.42E-9 T 12-10-2018 MIM_c22010 1b2a7f4b67092197204677248b8b7238 435 SMART SM01086 318 413 7.9E-32 T 12-10-2018 IPR019489 Clp ATPase, C-terminal MIM_c22010 1b2a7f4b67092197204677248b8b7238 435 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 318 395 1.6E-16 T 12-10-2018 IPR019489 Clp ATPase, C-terminal MIM_c22010 1b2a7f4b67092197204677248b8b7238 435 Gene3D G3DSA:3.40.50.300 58 316 2.2E-108 T 12-10-2018 MIM_c22010 1b2a7f4b67092197204677248b8b7238 435 Pfam PF07724 AAA domain (Cdc48 subfamily) 115 311 3.1E-47 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MIM_c09180 fb83624d84954afb14b608caca1d1a18 85 Pfam PF00196 Bacterial regulatory proteins, luxR family 16 69 1.6E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MIM_c09180 fb83624d84954afb14b608caca1d1a18 85 SUPERFAMILY SSF46894 10 72 1.63E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MIM_c09180 fb83624d84954afb14b608caca1d1a18 85 Gene3D G3DSA:1.10.10.10 12 73 4.1E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c09180 fb83624d84954afb14b608caca1d1a18 85 SMART SM00421 14 71 1.9E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MIM_c09180 fb83624d84954afb14b608caca1d1a18 85 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 47 59 3.9E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MIM_c09180 fb83624d84954afb14b608caca1d1a18 85 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 17 31 3.9E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MIM_c09180 fb83624d84954afb14b608caca1d1a18 85 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 31 47 3.9E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MIM_c15800 82807d037bf47da0579f1bed8ff7325d 219 Pfam PF05191 Adenylate kinase, active site lid 123 158 1.8E-17 T 12-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 MIM_c15800 82807d037bf47da0579f1bed8ff7325d 219 PRINTS PR00094 Adenylate kinase signature 173 187 7.4E-34 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MIM_c15800 82807d037bf47da0579f1bed8ff7325d 219 PRINTS PR00094 Adenylate kinase signature 156 171 7.4E-34 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MIM_c15800 82807d037bf47da0579f1bed8ff7325d 219 PRINTS PR00094 Adenylate kinase signature 32 46 7.4E-34 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MIM_c15800 82807d037bf47da0579f1bed8ff7325d 219 PRINTS PR00094 Adenylate kinase signature 4 17 7.4E-34 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MIM_c15800 82807d037bf47da0579f1bed8ff7325d 219 PRINTS PR00094 Adenylate kinase signature 81 97 7.4E-34 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MIM_c15800 82807d037bf47da0579f1bed8ff7325d 219 Gene3D G3DSA:3.40.50.300 1 217 9.3E-79 T 12-10-2018 MIM_c15800 82807d037bf47da0579f1bed8ff7325d 219 TIGRFAM TIGR01351 adk: adenylate kinase 2 216 6.1E-75 T 12-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 MIM_c15800 82807d037bf47da0579f1bed8ff7325d 219 SUPERFAMILY SSF52540 1 216 9.46E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c15800 82807d037bf47da0579f1bed8ff7325d 219 Pfam PF00406 Adenylate kinase 5 185 8.8E-57 T 12-10-2018 MIM_c15800 82807d037bf47da0579f1bed8ff7325d 219 Hamap MF_00235 Adenylate kinase [adk]. 1 217 51.677 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MIM_c15800 82807d037bf47da0579f1bed8ff7325d 219 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 12-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MIM_c26960 88296587ef72597f85659df5a464fc03 844 Pfam PF00577 Outer membrane usher protein 196 742 9.3E-146 T 12-10-2018 IPR000015 Outer membrane usher protein GO:0009297|GO:0015473|GO:0016020 MIM_c26960 88296587ef72597f85659df5a464fc03 844 Gene3D G3DSA:3.10.20.410 31 156 2.9E-26 T 12-10-2018 MIM_c26960 88296587ef72597f85659df5a464fc03 844 Gene3D G3DSA:2.60.40.2610 665 755 4.0E-24 T 12-10-2018 MIM_c26960 88296587ef72597f85659df5a464fc03 844 SUPERFAMILY SSF141729 32 156 3.53E-26 T 12-10-2018 IPR037224 PapC, N-terminal domain superfamily GO:0005515 MIM_c26960 88296587ef72597f85659df5a464fc03 844 Pfam PF13954 PapC N-terminal domain 33 178 3.3E-40 T 12-10-2018 IPR025885 PapC, N-terminal domain GO:0005515 MIM_c26960 88296587ef72597f85659df5a464fc03 844 Gene3D G3DSA:2.60.40.3110 271 360 3.8E-36 T 12-10-2018 MIM_c26960 88296587ef72597f85659df5a464fc03 844 ProSitePatterns PS01151 Fimbrial biogenesis outer membrane usher protein signature. 313 323 - T 12-10-2018 IPR018030 Fimbrial membrane usher, conserved site MIM_c26960 88296587ef72597f85659df5a464fc03 844 Pfam PF13953 PapC C-terminal domain 759 823 1.1E-17 T 12-10-2018 IPR025949 PapC-like, C-terminal domain MIM_c26960 88296587ef72597f85659df5a464fc03 844 Gene3D G3DSA:2.60.40.2070 757 844 1.2E-14 T 12-10-2018 MIM_c01390 0edcd5a0fe2f23edb5c673f106e39921 281 Pfam PF01261 Xylose isomerase-like TIM barrel 25 223 5.8E-18 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MIM_c01390 0edcd5a0fe2f23edb5c673f106e39921 281 SUPERFAMILY SSF51658 7 271 9.95E-45 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily MIM_c01390 0edcd5a0fe2f23edb5c673f106e39921 281 Gene3D G3DSA:3.20.20.150 1 274 3.4E-47 T 12-10-2018 MIM_c14110 5b73431c18e69ee3d0e4c2347a5cda3a 494 Pfam PF08529 NusA N-terminal domain 4 127 4.5E-35 T 12-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 MIM_c14110 5b73431c18e69ee3d0e4c2347a5cda3a 494 Gene3D G3DSA:3.30.1480.10 1 132 6.5E-40 T 12-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 MIM_c14110 5b73431c18e69ee3d0e4c2347a5cda3a 494 SUPERFAMILY SSF47794 359 418 3.14E-16 T 12-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 MIM_c14110 5b73431c18e69ee3d0e4c2347a5cda3a 494 SUPERFAMILY SSF50249 135 201 4.05E-16 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c14110 5b73431c18e69ee3d0e4c2347a5cda3a 494 SMART SM00316 136 202 7.1E-10 T 12-10-2018 IPR022967 RNA-binding domain, S1 MIM_c14110 5b73431c18e69ee3d0e4c2347a5cda3a 494 SUPERFAMILY SSF69705 1 129 2.22E-39 T 12-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 MIM_c14110 5b73431c18e69ee3d0e4c2347a5cda3a 494 Pfam PF14520 Helix-hairpin-helix domain 431 485 2.0E-11 T 12-10-2018 MIM_c14110 5b73431c18e69ee3d0e4c2347a5cda3a 494 Gene3D G3DSA:3.30.300.20 280 348 1.2E-23 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta MIM_c14110 5b73431c18e69ee3d0e4c2347a5cda3a 494 Pfam PF00575 S1 RNA binding domain 139 194 2.7E-7 T 12-10-2018 IPR003029 S1 domain GO:0003676 MIM_c14110 5b73431c18e69ee3d0e4c2347a5cda3a 494 Gene3D G3DSA:3.30.300.20 201 279 3.5E-30 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta MIM_c14110 5b73431c18e69ee3d0e4c2347a5cda3a 494 SUPERFAMILY SSF54814 281 344 2.49E-13 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 MIM_c14110 5b73431c18e69ee3d0e4c2347a5cda3a 494 SUPERFAMILY SSF54814 202 279 2.29E-28 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 MIM_c14110 5b73431c18e69ee3d0e4c2347a5cda3a 494 Pfam PF13184 NusA-like KH domain 232 299 5.2E-23 T 12-10-2018 IPR025249 KH domain, NusA-like GO:0003723 MIM_c14110 5b73431c18e69ee3d0e4c2347a5cda3a 494 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 412 28.821 T 12-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 MIM_c14110 5b73431c18e69ee3d0e4c2347a5cda3a 494 Gene3D G3DSA:1.10.150.20 430 488 2.4E-21 T 12-10-2018 MIM_c14110 5b73431c18e69ee3d0e4c2347a5cda3a 494 SUPERFAMILY SSF47794 428 489 1.57E-15 T 12-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 MIM_c14110 5b73431c18e69ee3d0e4c2347a5cda3a 494 Gene3D G3DSA:1.10.150.20 356 423 4.4E-28 T 12-10-2018 MIM_c14110 5b73431c18e69ee3d0e4c2347a5cda3a 494 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 343 1.3E-120 T 12-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 MIM_c14110 5b73431c18e69ee3d0e4c2347a5cda3a 494 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 444 488 1.4E-14 T 12-10-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication MIM_c14110 5b73431c18e69ee3d0e4c2347a5cda3a 494 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 367 416 2.0E-20 T 12-10-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication MIM_c14110 5b73431c18e69ee3d0e4c2347a5cda3a 494 Gene3D G3DSA:2.40.50.140 137 200 2.5E-20 T 12-10-2018 MIM_c07200 daad60eec94c3fc8786dd91598b687f5 442 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 141 161 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 MIM_c07200 daad60eec94c3fc8786dd91598b687f5 442 Pfam PF00919 Uncharacterized protein family UPF0004 5 88 5.9E-20 T 12-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 MIM_c07200 daad60eec94c3fc8786dd91598b687f5 442 Gene3D G3DSA:3.80.30.20 135 375 3.4E-72 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe MIM_c07200 daad60eec94c3fc8786dd91598b687f5 442 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 4 438 61.235 T 12-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 MIM_c07200 daad60eec94c3fc8786dd91598b687f5 442 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 5 436 1.1E-100 T 12-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 MIM_c07200 daad60eec94c3fc8786dd91598b687f5 442 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 5 435 2.8E-176 T 12-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 MIM_c07200 daad60eec94c3fc8786dd91598b687f5 442 SUPERFAMILY SSF102114 119 367 6.02E-54 T 12-10-2018 MIM_c07200 daad60eec94c3fc8786dd91598b687f5 442 Gene3D G3DSA:2.40.50.140 377 440 1.8E-17 T 12-10-2018 MIM_c07200 daad60eec94c3fc8786dd91598b687f5 442 Pfam PF04055 Radical SAM superfamily 143 319 4.0E-29 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MIM_c07200 daad60eec94c3fc8786dd91598b687f5 442 SMART SM00729 137 362 1.1E-51 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MIM_c07200 daad60eec94c3fc8786dd91598b687f5 442 Gene3D G3DSA:3.40.50.12160 5 124 1.4E-27 T 12-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily MIM_c07200 daad60eec94c3fc8786dd91598b687f5 442 Pfam PF01938 TRAM domain 375 436 1.6E-4 T 12-10-2018 IPR002792 TRAM domain MIM_c24350 26f6b68a629ca87d48702e6b35d11911 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 4.1E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c24350 26f6b68a629ca87d48702e6b35d11911 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 413 4.1E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c24350 26f6b68a629ca87d48702e6b35d11911 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 437 4.1E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c24350 26f6b68a629ca87d48702e6b35d11911 467 SMART SM00304 189 242 8.0E-12 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MIM_c24350 26f6b68a629ca87d48702e6b35d11911 467 SUPERFAMILY SSF55874 303 459 1.18E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c24350 26f6b68a629ca87d48702e6b35d11911 467 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 347 441 1.6E-14 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c24350 26f6b68a629ca87d48702e6b35d11911 467 SMART SM00388 243 302 1.3E-6 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MIM_c24350 26f6b68a629ca87d48702e6b35d11911 467 SMART SM00387 344 459 1.2E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c24350 26f6b68a629ca87d48702e6b35d11911 467 SUPERFAMILY SSF158472 189 239 4.97E-6 T 12-10-2018 MIM_c24350 26f6b68a629ca87d48702e6b35d11911 467 SUPERFAMILY SSF47384 227 298 2.75E-10 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MIM_c24350 26f6b68a629ca87d48702e6b35d11911 467 Gene3D G3DSA:3.30.565.10 301 463 2.7E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c24350 26f6b68a629ca87d48702e6b35d11911 467 Pfam PF00672 HAMP domain 189 238 1.8E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MIM_c24350 26f6b68a629ca87d48702e6b35d11911 467 Pfam PF16524 Periplasmic domain of Sensor histidine kinase RisS 54 159 1.7E-29 T 12-10-2018 IPR032408 Sensor histidine kinase RisS, periplasmic domain MIM_c24350 26f6b68a629ca87d48702e6b35d11911 467 Pfam PF00512 His Kinase A (phospho-acceptor) domain 245 298 2.3E-6 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MIM_c24350 26f6b68a629ca87d48702e6b35d11911 467 Gene3D G3DSA:1.10.287.130 187 297 6.9E-20 T 12-10-2018 MIM_c24350 26f6b68a629ca87d48702e6b35d11911 467 Gene3D G3DSA:3.30.450.300 41 163 1.1E-33 T 12-10-2018 IPR038421 Sensor histidine kinase RisS, periplasmic domain superfamily MIM_c03090 e01a7ad970fc4305d94b88494d23252e 486 SUPERFAMILY SSF51905 44 263 2.43E-29 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c03090 e01a7ad970fc4305d94b88494d23252e 486 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 44 264 5.2E-15 T 12-10-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase MIM_c03090 e01a7ad970fc4305d94b88494d23252e 486 SUPERFAMILY SSF51905 211 352 3.13E-15 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c03090 e01a7ad970fc4305d94b88494d23252e 486 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 181 199 8.5E-8 T 12-10-2018 MIM_c03090 e01a7ad970fc4305d94b88494d23252e 486 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 226 244 8.5E-8 T 12-10-2018 MIM_c03090 e01a7ad970fc4305d94b88494d23252e 486 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 46 65 8.5E-8 T 12-10-2018 MIM_c03090 e01a7ad970fc4305d94b88494d23252e 486 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 45 67 8.9E-10 T 12-10-2018 MIM_c03090 e01a7ad970fc4305d94b88494d23252e 486 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 226 251 8.9E-10 T 12-10-2018 MIM_c03090 e01a7ad970fc4305d94b88494d23252e 486 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 184 193 8.9E-10 T 12-10-2018 MIM_c03090 e01a7ad970fc4305d94b88494d23252e 486 Gene3D G3DSA:3.50.50.60 36 380 6.6E-38 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c09030 4cb9ec142f96fc3c7651715fc0d2ec9d 102 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 19 97 6.5E-20 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 MIM_c09030 4cb9ec142f96fc3c7651715fc0d2ec9d 102 SUPERFAMILY SSF141000 3 100 1.09E-23 T 12-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 MIM_c09030 4cb9ec142f96fc3c7651715fc0d2ec9d 102 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 102 22.358 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 MIM_c09030 4cb9ec142f96fc3c7651715fc0d2ec9d 102 Gene3D G3DSA:1.10.20.60 1 100 1.1E-22 T 12-10-2018 MIM_c09030 4cb9ec142f96fc3c7651715fc0d2ec9d 102 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 102 2.5E-25 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 MIM_c16180 97f53896ce43d964d32e803bd856dd5f 234 SUPERFAMILY SSF46785 156 228 6.22E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c16180 97f53896ce43d964d32e803bd856dd5f 234 SUPERFAMILY SSF51206 9 149 2.88E-26 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like MIM_c16180 97f53896ce43d964d32e803bd856dd5f 234 Gene3D G3DSA:1.10.10.10 154 229 1.3E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c16180 97f53896ce43d964d32e803bd856dd5f 234 SMART SM00100 17 139 2.3E-13 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain MIM_c16180 97f53896ce43d964d32e803bd856dd5f 234 Pfam PF00027 Cyclic nucleotide-binding domain 47 126 1.8E-13 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain MIM_c16180 97f53896ce43d964d32e803bd856dd5f 234 Gene3D G3DSA:2.60.120.10 5 153 1.9E-35 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c16180 97f53896ce43d964d32e803bd856dd5f 234 SMART SM00419 173 221 2.3E-4 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MIM_c16180 97f53896ce43d964d32e803bd856dd5f 234 Pfam PF13545 Crp-like helix-turn-helix domain 159 227 4.4E-12 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MIM_c01560 847fa3ef4bd37b4313d00f731b321e3f 281 Gene3D G3DSA:3.40.50.300 17 280 9.7E-57 T 12-10-2018 MIM_c01560 847fa3ef4bd37b4313d00f731b321e3f 281 SMART SM00382 43 212 1.0E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c01560 847fa3ef4bd37b4313d00f731b321e3f 281 Pfam PF00005 ABC transporter 34 162 2.2E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c01560 847fa3ef4bd37b4313d00f731b321e3f 281 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c01560 847fa3ef4bd37b4313d00f731b321e3f 281 SUPERFAMILY SSF52540 19 227 1.02E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c25420 a93594ff86897cdd95d83027ab7d8db0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 3.7E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c25420 a93594ff86897cdd95d83027ab7d8db0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 3.7E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c25420 a93594ff86897cdd95d83027ab7d8db0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 3.7E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c25420 a93594ff86897cdd95d83027ab7d8db0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 3.7E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c25420 a93594ff86897cdd95d83027ab7d8db0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 3.7E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c25420 a93594ff86897cdd95d83027ab7d8db0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 3.7E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c25420 a93594ff86897cdd95d83027ab7d8db0 255 SUPERFAMILY SSF51735 10 253 3.23E-84 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c25420 a93594ff86897cdd95d83027ab7d8db0 255 Gene3D G3DSA:3.40.50.720 1 254 1.4E-80 T 12-10-2018 MIM_c25420 a93594ff86897cdd95d83027ab7d8db0 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 250 2.0E-64 T 12-10-2018 MIM_c25420 a93594ff86897cdd95d83027ab7d8db0 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c25420 a93594ff86897cdd95d83027ab7d8db0 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 2.3E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c25420 a93594ff86897cdd95d83027ab7d8db0 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 2.3E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c25420 a93594ff86897cdd95d83027ab7d8db0 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 2.3E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c29930 bdc3bfb8c9d0a053edb67961dd901965 580 Gene3D G3DSA:3.30.930.10 11 468 5.0E-231 T 12-10-2018 MIM_c29930 bdc3bfb8c9d0a053edb67961dd901965 580 Pfam PF04073 Aminoacyl-tRNA editing domain 257 382 1.4E-26 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MIM_c29930 bdc3bfb8c9d0a053edb67961dd901965 580 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 574 39.951 T 12-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MIM_c29930 bdc3bfb8c9d0a053edb67961dd901965 580 PIRSF PIRSF001535 1 577 2.0E-261 T 12-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MIM_c29930 bdc3bfb8c9d0a053edb67961dd901965 580 Gene3D G3DSA:3.90.960.10 240 392 5.0E-231 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 MIM_c29930 bdc3bfb8c9d0a053edb67961dd901965 580 SUPERFAMILY SSF55826 218 393 3.01E-31 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 MIM_c29930 bdc3bfb8c9d0a053edb67961dd901965 580 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 1.4E-17 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MIM_c29930 bdc3bfb8c9d0a053edb67961dd901965 580 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 1.4E-17 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MIM_c29930 bdc3bfb8c9d0a053edb67961dd901965 580 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 1.4E-17 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MIM_c29930 bdc3bfb8c9d0a053edb67961dd901965 580 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 1.4E-17 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MIM_c29930 bdc3bfb8c9d0a053edb67961dd901965 580 Gene3D G3DSA:3.40.50.800 4 554 5.0E-231 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily MIM_c29930 bdc3bfb8c9d0a053edb67961dd901965 580 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 568 1.9E-227 T 12-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MIM_c29930 bdc3bfb8c9d0a053edb67961dd901965 580 SUPERFAMILY SSF55681 10 481 1.91E-97 T 12-10-2018 MIM_c29930 bdc3bfb8c9d0a053edb67961dd901965 580 Pfam PF03129 Anticodon binding domain 478 571 2.0E-17 T 12-10-2018 IPR004154 Anticodon-binding MIM_c29930 bdc3bfb8c9d0a053edb67961dd901965 580 SUPERFAMILY SSF52954 466 576 3.93E-31 T 12-10-2018 MIM_c29930 bdc3bfb8c9d0a053edb67961dd901965 580 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 462 5.4E-46 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c23200 2e2fee58c442f87223191122e37662ef 501 Gene3D G3DSA:3.30.465.40 20 252 1.0E-60 T 12-10-2018 MIM_c23200 2e2fee58c442f87223191122e37662ef 501 Pfam PF02913 FAD linked oxidases, C-terminal domain 232 472 8.1E-65 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 MIM_c23200 2e2fee58c442f87223191122e37662ef 501 Pfam PF01565 FAD binding domain 58 196 7.1E-39 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MIM_c23200 2e2fee58c442f87223191122e37662ef 501 Gene3D G3DSA:3.30.70.2740 353 433 6.6E-7 T 12-10-2018 MIM_c23200 2e2fee58c442f87223191122e37662ef 501 SUPERFAMILY SSF56176 21 233 2.71E-64 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MIM_c23200 2e2fee58c442f87223191122e37662ef 501 SUPERFAMILY SSF55103 207 475 1.96E-71 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MIM_c41120 6d7a2b94320f17de5699a9420e067139 382 Gene3D G3DSA:2.40.110.10 121 230 3.3E-27 T 12-10-2018 MIM_c41120 6d7a2b94320f17de5699a9420e067139 382 Gene3D G3DSA:1.20.140.10 231 375 7.9E-41 T 12-10-2018 MIM_c41120 6d7a2b94320f17de5699a9420e067139 382 SUPERFAMILY SSF56645 1 225 1.44E-55 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c41120 6d7a2b94320f17de5699a9420e067139 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 225 372 7.2E-40 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MIM_c41120 6d7a2b94320f17de5699a9420e067139 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 117 3.5E-21 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c41120 6d7a2b94320f17de5699a9420e067139 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 211 1.1E-16 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MIM_c41120 6d7a2b94320f17de5699a9420e067139 382 SUPERFAMILY SSF47203 225 375 2.74E-42 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c41120 6d7a2b94320f17de5699a9420e067139 382 Gene3D G3DSA:1.10.540.10 1 119 1.1E-27 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c29240 740b734bc92c2c3ff76e7eb03e4b860a 409 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 10 407 47.674 T 12-10-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 MIM_c29240 740b734bc92c2c3ff76e7eb03e4b860a 409 SUPERFAMILY SSF55174 327 404 1.14E-16 T 12-10-2018 MIM_c29240 740b734bc92c2c3ff76e7eb03e4b860a 409 SUPERFAMILY SSF52374 36 328 1.13E-88 T 12-10-2018 MIM_c29240 740b734bc92c2c3ff76e7eb03e4b860a 409 Gene3D G3DSA:1.10.240.10 231 338 6.8E-31 T 12-10-2018 MIM_c29240 740b734bc92c2c3ff76e7eb03e4b860a 409 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 27 407 2.9E-117 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MIM_c29240 740b734bc92c2c3ff76e7eb03e4b860a 409 Gene3D G3DSA:3.40.50.620 11 230 1.4E-68 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c29240 740b734bc92c2c3ff76e7eb03e4b860a 409 Pfam PF01479 S4 domain 349 391 2.5E-6 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c29240 740b734bc92c2c3ff76e7eb03e4b860a 409 Gene3D G3DSA:3.10.290.10 339 407 6.8E-17 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MIM_c29240 740b734bc92c2c3ff76e7eb03e4b860a 409 Pfam PF00579 tRNA synthetases class I (W and Y) 44 328 2.6E-72 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c29240 740b734bc92c2c3ff76e7eb03e4b860a 409 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 54 64 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c29240 740b734bc92c2c3ff76e7eb03e4b860a 409 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 58 80 2.6E-25 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MIM_c29240 740b734bc92c2c3ff76e7eb03e4b860a 409 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 173 188 2.6E-25 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MIM_c29240 740b734bc92c2c3ff76e7eb03e4b860a 409 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 190 212 2.6E-25 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MIM_c29240 740b734bc92c2c3ff76e7eb03e4b860a 409 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 223 235 2.6E-25 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MIM_c20470 88965e2b81074d9d056e2bbc5ede69c0 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.6E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c20470 88965e2b81074d9d056e2bbc5ede69c0 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.6E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c20470 88965e2b81074d9d056e2bbc5ede69c0 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.6E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c20470 88965e2b81074d9d056e2bbc5ede69c0 296 Gene3D G3DSA:1.10.10.10 3 87 5.8E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c20470 88965e2b81074d9d056e2bbc5ede69c0 296 SUPERFAMILY SSF46785 6 90 7.09E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c20470 88965e2b81074d9d056e2bbc5ede69c0 296 SUPERFAMILY SSF53850 91 295 1.1E-37 T 12-10-2018 MIM_c20470 88965e2b81074d9d056e2bbc5ede69c0 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 65 1.7E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c20470 88965e2b81074d9d056e2bbc5ede69c0 296 Gene3D G3DSA:3.40.190.290 94 296 4.8E-50 T 12-10-2018 MIM_c20470 88965e2b81074d9d056e2bbc5ede69c0 296 Pfam PF03466 LysR substrate binding domain 92 295 8.7E-33 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c26590 2bdcd6de13f25f3de4bd017f7e5b2c44 255 Gene3D G3DSA:1.10.12.10 198 255 3.2E-24 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MIM_c26590 2bdcd6de13f25f3de4bd017f7e5b2c44 255 SUPERFAMILY SSF52096 2 254 2.21E-82 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c26590 2bdcd6de13f25f3de4bd017f7e5b2c44 255 Gene3D G3DSA:3.90.226.10 1 197 1.7E-71 T 12-10-2018 MIM_c26590 2bdcd6de13f25f3de4bd017f7e5b2c44 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 254 6.3E-59 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c26590 2bdcd6de13f25f3de4bd017f7e5b2c44 255 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 96 116 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 MIM_c25640 a83694a49d3cf0d01d8f9db43a8490d9 399 Gene3D G3DSA:2.40.50.100 65 228 4.9E-80 T 12-10-2018 MIM_c25640 a83694a49d3cf0d01d8f9db43a8490d9 399 Gene3D G3DSA:1.10.287.470 99 190 4.9E-80 T 12-10-2018 MIM_c25640 a83694a49d3cf0d01d8f9db43a8490d9 399 Gene3D G3DSA:2.40.30.170 54 323 4.9E-80 T 12-10-2018 MIM_c25640 a83694a49d3cf0d01d8f9db43a8490d9 399 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 43 386 7.6E-47 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MIM_c25640 a83694a49d3cf0d01d8f9db43a8490d9 399 SUPERFAMILY SSF111369 55 240 1.14E-20 T 12-10-2018 MIM_c25640 a83694a49d3cf0d01d8f9db43a8490d9 399 Gene3D G3DSA:2.40.420.20 50 385 4.9E-80 T 12-10-2018 MIM_c25640 a83694a49d3cf0d01d8f9db43a8490d9 399 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 62 273 6.2E-17 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MIM_c35020 497a80fc27e2e250406a250fc2188f4b 252 Gene3D G3DSA:3.40.50.300 2 240 1.0E-57 T 12-10-2018 MIM_c35020 497a80fc27e2e250406a250fc2188f4b 252 SUPERFAMILY SSF52540 5 232 2.3E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c35020 497a80fc27e2e250406a250fc2188f4b 252 Pfam PF00005 ABC transporter 20 168 2.5E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c35020 497a80fc27e2e250406a250fc2188f4b 252 SMART SM00382 29 241 1.4E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c35020 497a80fc27e2e250406a250fc2188f4b 252 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c30460 adde664f99586a89c3aeb70bd3c0245e 504 Pfam PF00206 Lyase 67 309 3.4E-55 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal MIM_c30460 adde664f99586a89c3aeb70bd3c0245e 504 PRINTS PR00149 Fumarate lyase superfamily signature 156 174 8.3E-25 T 12-10-2018 IPR000362 Fumarate lyase family MIM_c30460 adde664f99586a89c3aeb70bd3c0245e 504 PRINTS PR00149 Fumarate lyase superfamily signature 284 300 8.3E-25 T 12-10-2018 IPR000362 Fumarate lyase family MIM_c30460 adde664f99586a89c3aeb70bd3c0245e 504 PRINTS PR00149 Fumarate lyase superfamily signature 240 267 8.3E-25 T 12-10-2018 IPR000362 Fumarate lyase family MIM_c30460 adde664f99586a89c3aeb70bd3c0245e 504 PRINTS PR00149 Fumarate lyase superfamily signature 111 129 8.3E-25 T 12-10-2018 IPR000362 Fumarate lyase family MIM_c30460 adde664f99586a89c3aeb70bd3c0245e 504 Gene3D G3DSA:1.10.40.30 370 451 2.2E-133 T 12-10-2018 MIM_c30460 adde664f99586a89c3aeb70bd3c0245e 504 TIGRFAM TIGR00838 argH: argininosuccinate lyase 44 471 5.6E-113 T 12-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MIM_c30460 adde664f99586a89c3aeb70bd3c0245e 504 Hamap MF_00006 Argininosuccinate lyase [argH]. 9 471 30.406 T 12-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MIM_c30460 adde664f99586a89c3aeb70bd3c0245e 504 Gene3D G3DSA:1.20.200.10 128 467 2.2E-133 T 12-10-2018 MIM_c30460 adde664f99586a89c3aeb70bd3c0245e 504 PRINTS PR00145 Argininosuccinate lyase family signature 240 264 2.8E-37 T 12-10-2018 MIM_c30460 adde664f99586a89c3aeb70bd3c0245e 504 PRINTS PR00145 Argininosuccinate lyase family signature 151 171 2.8E-37 T 12-10-2018 MIM_c30460 adde664f99586a89c3aeb70bd3c0245e 504 PRINTS PR00145 Argininosuccinate lyase family signature 202 218 2.8E-37 T 12-10-2018 MIM_c30460 adde664f99586a89c3aeb70bd3c0245e 504 PRINTS PR00145 Argininosuccinate lyase family signature 110 132 2.8E-37 T 12-10-2018 MIM_c30460 adde664f99586a89c3aeb70bd3c0245e 504 PRINTS PR00145 Argininosuccinate lyase family signature 284 300 2.8E-37 T 12-10-2018 MIM_c30460 adde664f99586a89c3aeb70bd3c0245e 504 SUPERFAMILY SSF48557 33 470 6.13E-100 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 MIM_c30460 adde664f99586a89c3aeb70bd3c0245e 504 Pfam PF14698 Argininosuccinate lyase C-terminal 373 449 3.2E-15 T 12-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MIM_c30460 adde664f99586a89c3aeb70bd3c0245e 504 Gene3D G3DSA:1.10.275.10 44 238 2.2E-133 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal MIM_c09470 3ff3c7b6ea9ba364e445a952bb852f96 230 SMART SM00862 150 226 2.7E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MIM_c09470 3ff3c7b6ea9ba364e445a952bb852f96 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 226 2.8E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MIM_c09470 3ff3c7b6ea9ba364e445a952bb852f96 230 SUPERFAMILY SSF46894 135 227 1.21E-24 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MIM_c09470 3ff3c7b6ea9ba364e445a952bb852f96 230 SMART SM00448 8 118 5.0E-40 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c09470 3ff3c7b6ea9ba364e445a952bb852f96 230 Gene3D G3DSA:1.10.10.10 136 229 1.1E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c09470 3ff3c7b6ea9ba364e445a952bb852f96 230 Gene3D G3DSA:3.40.50.2300 2 134 8.1E-35 T 12-10-2018 MIM_c09470 3ff3c7b6ea9ba364e445a952bb852f96 230 SUPERFAMILY SSF52172 6 130 1.99E-39 T 12-10-2018 IPR011006 CheY-like superfamily MIM_c09470 3ff3c7b6ea9ba364e445a952bb852f96 230 Pfam PF00072 Response regulator receiver domain 10 118 3.9E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c26820 ac1fcb86c20da8f2f40ccd5be98a99f5 557 Pfam PF00005 ABC transporter 343 476 5.0E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c26820 ac1fcb86c20da8f2f40ccd5be98a99f5 557 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 2 556 8.8E-290 T 12-10-2018 IPR022374 Energy-dependent translational throttle protein EttA GO:0045900 MIM_c26820 ac1fcb86c20da8f2f40ccd5be98a99f5 557 Pfam PF12848 ABC transporter 233 308 2.9E-13 T 12-10-2018 IPR032781 ABC-transporter extension domain MIM_c26820 ac1fcb86c20da8f2f40ccd5be98a99f5 557 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c26820 ac1fcb86c20da8f2f40ccd5be98a99f5 557 Gene3D G3DSA:3.40.50.300 1 288 9.6E-82 T 12-10-2018 MIM_c26820 ac1fcb86c20da8f2f40ccd5be98a99f5 557 SUPERFAMILY SSF52540 305 532 1.87E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c26820 ac1fcb86c20da8f2f40ccd5be98a99f5 557 SUPERFAMILY SSF52540 12 239 2.33E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c26820 ac1fcb86c20da8f2f40ccd5be98a99f5 557 Gene3D G3DSA:3.40.50.300 289 556 1.6E-74 T 12-10-2018 MIM_c26820 ac1fcb86c20da8f2f40ccd5be98a99f5 557 SMART SM00382 351 529 9.3E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c26820 ac1fcb86c20da8f2f40ccd5be98a99f5 557 SMART SM00382 31 239 1.3E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c26820 ac1fcb86c20da8f2f40ccd5be98a99f5 557 Pfam PF00005 ABC transporter 22 194 2.2E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c29620 63bda2ce5c64cf90f7c2659d01d6d17e 408 Gene3D G3DSA:3.60.70.12 9 278 4.5E-91 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MIM_c29620 63bda2ce5c64cf90f7c2659d01d6d17e 408 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 408 149.997 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MIM_c29620 63bda2ce5c64cf90f7c2659d01d6d17e 408 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 15 408 6.9E-125 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MIM_c29620 63bda2ce5c64cf90f7c2659d01d6d17e 408 Gene3D G3DSA:3.10.20.340 279 408 1.9E-38 T 12-10-2018 MIM_c29620 63bda2ce5c64cf90f7c2659d01d6d17e 408 SUPERFAMILY SSF56266 16 405 2.35E-136 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MIM_c29620 63bda2ce5c64cf90f7c2659d01d6d17e 408 Pfam PF01960 ArgJ family 23 408 3.0E-140 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MIM_c29620 63bda2ce5c64cf90f7c2659d01d6d17e 408 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 24 406 8.0E-145 T 12-10-2018 MIM_c22800 131239acc4ba64e351db04e620a70b76 226 SUPERFAMILY SSF52540 13 223 1.4E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c22800 131239acc4ba64e351db04e620a70b76 226 Hamap MF_00238 Cytidylate kinase [cmk]. 12 226 32.52 T 12-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 MIM_c22800 131239acc4ba64e351db04e620a70b76 226 Gene3D G3DSA:3.40.50.300 8 226 1.1E-74 T 12-10-2018 MIM_c22800 131239acc4ba64e351db04e620a70b76 226 Pfam PF02224 Cytidylate kinase 14 221 5.5E-72 T 12-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 MIM_c22800 131239acc4ba64e351db04e620a70b76 226 TIGRFAM TIGR00017 cmk: cytidylate kinase 12 220 7.6E-73 T 12-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 MIM_c36150 95d420681efc11608e0d26bbe57a477c 403 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 7 396 52.399 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MIM_c36150 95d420681efc11608e0d26bbe57a477c 403 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 86 100 - T 12-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MIM_c36150 95d420681efc11608e0d26bbe57a477c 403 SUPERFAMILY SSF53686 9 394 1.7E-149 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MIM_c36150 95d420681efc11608e0d26bbe57a477c 403 Gene3D G3DSA:3.40.50.1100 15 211 8.2E-189 T 12-10-2018 MIM_c36150 95d420681efc11608e0d26bbe57a477c 403 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 12 395 6.7E-195 T 12-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MIM_c36150 95d420681efc11608e0d26bbe57a477c 403 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 58 383 1.6E-46 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MIM_c36150 95d420681efc11608e0d26bbe57a477c 403 Gene3D G3DSA:3.40.50.1100 59 389 8.2E-189 T 12-10-2018 MIM_c36150 95d420681efc11608e0d26bbe57a477c 403 PIRSF PIRSF001413 3 402 8.9E-164 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MIM_c14040 de77f515e3e51e69939a851f3aa904d5 111 SUPERFAMILY SSF47598 72 109 1.48E-5 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 MIM_c14040 de77f515e3e51e69939a851f3aa904d5 111 SUPERFAMILY SSF143100 1 76 8.37E-7 T 12-10-2018 IPR035069 TTHA1013/TTHA0281-like MIM_c14040 de77f515e3e51e69939a851f3aa904d5 111 Pfam PF05534 HicB family 55 104 4.1E-21 T 12-10-2018 IPR008651 Uncharacterised protein family HicB MIM_c28980 4e08adb34332b9defa0fd50c69e44521 762 Pfam PF01568 Molydopterin dinucleotide binding domain 642 749 2.4E-16 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 MIM_c28980 4e08adb34332b9defa0fd50c69e44521 762 Gene3D G3DSA:3.40.50.740 125 496 5.7E-71 T 12-10-2018 MIM_c28980 4e08adb34332b9defa0fd50c69e44521 762 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 18 754 3.4E-294 T 12-10-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 MIM_c28980 4e08adb34332b9defa0fd50c69e44521 762 Pfam PF00384 Molybdopterin oxidoreductase 114 487 9.6E-25 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c28980 4e08adb34332b9defa0fd50c69e44521 762 Gene3D G3DSA:2.40.40.20 642 755 4.6E-7 T 12-10-2018 MIM_c28980 4e08adb34332b9defa0fd50c69e44521 762 SUPERFAMILY SSF53706 52 625 1.57E-143 T 12-10-2018 MIM_c28980 4e08adb34332b9defa0fd50c69e44521 762 Gene3D G3DSA:3.40.228.10 189 411 5.7E-71 T 12-10-2018 MIM_c28980 4e08adb34332b9defa0fd50c69e44521 762 PIRSF PIRSF000144 1 759 0.0 T 12-10-2018 MIM_c28980 4e08adb34332b9defa0fd50c69e44521 762 SUPERFAMILY SSF50692 638 756 6.56E-20 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily MIM_c08680 c6ba506ef9fbf907bba1708bd450f14f 352 SMART SM00382 28 211 6.5E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c08680 c6ba506ef9fbf907bba1708bd450f14f 352 Gene3D G3DSA:2.40.50.140 285 339 5.8E-8 T 12-10-2018 MIM_c08680 c6ba506ef9fbf907bba1708bd450f14f 352 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 34 327 4.1E-107 T 12-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 MIM_c08680 c6ba506ef9fbf907bba1708bd450f14f 352 SUPERFAMILY SSF52540 4 243 1.77E-88 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c08680 c6ba506ef9fbf907bba1708bd450f14f 352 SUPERFAMILY SSF50331 237 347 1.59E-10 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MIM_c08680 c6ba506ef9fbf907bba1708bd450f14f 352 Pfam PF08402 TOBE domain 279 347 4.8E-9 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 MIM_c08680 c6ba506ef9fbf907bba1708bd450f14f 352 Gene3D G3DSA:3.40.50.300 3 221 8.0E-68 T 12-10-2018 MIM_c08680 c6ba506ef9fbf907bba1708bd450f14f 352 Pfam PF00005 ABC transporter 20 161 8.6E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c08680 c6ba506ef9fbf907bba1708bd450f14f 352 Gene3D G3DSA:2.40.50.940 222 284 5.8E-8 T 12-10-2018 MIM_c08680 c6ba506ef9fbf907bba1708bd450f14f 352 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c16700 005c0318d76409a38f6d1a2aaa538c62 467 Pfam PF00330 Aconitase family (aconitate hydratase) 7 458 6.3E-159 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c16700 005c0318d76409a38f6d1a2aaa538c62 467 ProSitePatterns PS01244 Aconitase family signature 2. 400 413 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MIM_c16700 005c0318d76409a38f6d1a2aaa538c62 467 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 2 466 3.1E-239 T 12-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 MIM_c16700 005c0318d76409a38f6d1a2aaa538c62 467 Gene3D G3DSA:3.30.499.10 324 467 2.7E-50 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 MIM_c16700 005c0318d76409a38f6d1a2aaa538c62 467 SUPERFAMILY SSF53732 3 466 3.27E-167 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 MIM_c16700 005c0318d76409a38f6d1a2aaa538c62 467 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MIM_c16700 005c0318d76409a38f6d1a2aaa538c62 467 Gene3D G3DSA:3.30.499.20 4 286 6.7E-97 T 12-10-2018 MIM_c16700 005c0318d76409a38f6d1a2aaa538c62 467 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 467 60.398 T 12-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 MIM_c16700 005c0318d76409a38f6d1a2aaa538c62 467 PRINTS PR00415 Aconitase family signature 108 116 8.6E-50 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c16700 005c0318d76409a38f6d1a2aaa538c62 467 PRINTS PR00415 Aconitase family signature 195 208 8.6E-50 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c16700 005c0318d76409a38f6d1a2aaa538c62 467 PRINTS PR00415 Aconitase family signature 286 300 8.6E-50 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c16700 005c0318d76409a38f6d1a2aaa538c62 467 PRINTS PR00415 Aconitase family signature 209 222 8.6E-50 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c16700 005c0318d76409a38f6d1a2aaa538c62 467 PRINTS PR00415 Aconitase family signature 400 413 8.6E-50 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c16700 005c0318d76409a38f6d1a2aaa538c62 467 PRINTS PR00415 Aconitase family signature 119 132 8.6E-50 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c16700 005c0318d76409a38f6d1a2aaa538c62 467 PRINTS PR00415 Aconitase family signature 82 95 8.6E-50 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c16700 005c0318d76409a38f6d1a2aaa538c62 467 PRINTS PR00415 Aconitase family signature 133 148 8.6E-50 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c16700 005c0318d76409a38f6d1a2aaa538c62 467 PRINTS PR00415 Aconitase family signature 343 354 8.6E-50 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c10140 a2b5dc23e3947ae3fe77caa3bab4fe3b 314 Pfam PF12833 Helix-turn-helix domain 242 314 1.0E-16 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c10140 a2b5dc23e3947ae3fe77caa3bab4fe3b 314 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 270 311 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MIM_c10140 a2b5dc23e3947ae3fe77caa3bab4fe3b 314 Gene3D G3DSA:1.10.10.60 213 314 4.8E-19 T 12-10-2018 MIM_c10140 a2b5dc23e3947ae3fe77caa3bab4fe3b 314 SMART SM00342 233 313 3.9E-17 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c10140 a2b5dc23e3947ae3fe77caa3bab4fe3b 314 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 299 314 7.4E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MIM_c10140 a2b5dc23e3947ae3fe77caa3bab4fe3b 314 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 284 299 7.4E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MIM_c10140 a2b5dc23e3947ae3fe77caa3bab4fe3b 314 SUPERFAMILY SSF46689 269 314 1.61E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c12470 2e32e7b067e87ff6f786689b3b015719 332 SUPERFAMILY SSF53850 118 287 5.61E-12 T 12-10-2018 MIM_c12470 2e32e7b067e87ff6f786689b3b015719 332 Gene3D G3DSA:3.40.190.150 36 321 5.6E-104 T 12-10-2018 MIM_c12470 2e32e7b067e87ff6f786689b3b015719 332 PIRSF PIRSF017082 1 331 1.4E-70 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c12470 2e32e7b067e87ff6f786689b3b015719 332 Gene3D G3DSA:3.40.190.10 133 256 5.6E-104 T 12-10-2018 MIM_c12470 2e32e7b067e87ff6f786689b3b015719 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 327 2.4E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c33490 01cb871b07ff5c2b17f44dcd82e080fd 159 Pfam PF03928 Haem-degrading 8 137 9.8E-25 T 12-10-2018 IPR005624 Haem-degrading MIM_c33490 01cb871b07ff5c2b17f44dcd82e080fd 159 SUPERFAMILY SSF143744 4 141 3.92E-33 T 12-10-2018 IPR038084 GlcG-like domain superfamily MIM_c33490 01cb871b07ff5c2b17f44dcd82e080fd 159 Gene3D G3DSA:3.30.450.150 1 143 3.7E-39 T 12-10-2018 IPR038084 GlcG-like domain superfamily MIM_c13410 e31f854cb8e026b61b5fb0765b6468f5 291 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 16 65 2.3E-8 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MIM_c13410 e31f854cb8e026b61b5fb0765b6468f5 291 Gene3D G3DSA:1.10.3720.10 80 285 6.8E-21 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c13410 e31f854cb8e026b61b5fb0765b6468f5 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 289 3.0E-31 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c13410 e31f854cb8e026b61b5fb0765b6468f5 291 SUPERFAMILY SSF161098 96 270 1.96E-28 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c30610 4a882c8729f024b98538fe69e559fc09 220 SUPERFAMILY SSF46689 2 60 2.59E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c30610 4a882c8729f024b98538fe69e559fc09 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 3.0E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c30610 4a882c8729f024b98538fe69e559fc09 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 3.0E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c30610 4a882c8729f024b98538fe69e559fc09 220 Gene3D G3DSA:1.10.357.10 1 176 3.7E-15 T 12-10-2018 MIM_c30610 4a882c8729f024b98538fe69e559fc09 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 48 4.1E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c32840 6c054ceea4d3e8e69492a91cd2ff560c 399 Gene3D G3DSA:2.40.50.940 242 297 1.3E-13 T 12-10-2018 MIM_c32840 6c054ceea4d3e8e69492a91cd2ff560c 399 SUPERFAMILY SSF50331 255 382 9.92E-15 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MIM_c32840 6c054ceea4d3e8e69492a91cd2ff560c 399 Gene3D G3DSA:3.40.50.300 4 241 5.3E-62 T 12-10-2018 MIM_c32840 6c054ceea4d3e8e69492a91cd2ff560c 399 Pfam PF00005 ABC transporter 20 180 2.1E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c32840 6c054ceea4d3e8e69492a91cd2ff560c 399 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c32840 6c054ceea4d3e8e69492a91cd2ff560c 399 Gene3D G3DSA:2.40.50.140 298 347 1.3E-13 T 12-10-2018 MIM_c32840 6c054ceea4d3e8e69492a91cd2ff560c 399 SUPERFAMILY SSF52540 5 263 5.2E-78 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c32840 6c054ceea4d3e8e69492a91cd2ff560c 399 SMART SM00382 29 238 3.2E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c17830 db6f6d151042cda3bfc9267ebda11077 183 Gene3D G3DSA:3.30.300.20 24 183 3.1E-31 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta MIM_c17830 db6f6d151042cda3bfc9267ebda11077 183 Pfam PF02566 OsmC-like protein 70 178 5.1E-23 T 12-10-2018 IPR003718 OsmC/Ohr family MIM_c17830 db6f6d151042cda3bfc9267ebda11077 183 SUPERFAMILY SSF82784 9 180 5.76E-30 T 12-10-2018 IPR036102 OsmC/Ohr superfamily MIM_c28650 49e2f0a03911d7978fd85592c2f9adbc 371 SUPERFAMILY SSF53448 31 229 1.33E-38 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MIM_c28650 49e2f0a03911d7978fd85592c2f9adbc 371 Pfam PF00535 Glycosyl transferase family 2 38 199 5.3E-30 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MIM_c28650 49e2f0a03911d7978fd85592c2f9adbc 371 Gene3D G3DSA:3.90.550.10 21 228 3.4E-38 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MIM_c15020 f8243346bd3d7c8cf033c4fa08562d5c 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.3E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c15020 f8243346bd3d7c8cf033c4fa08562d5c 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 1.3E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c15020 f8243346bd3d7c8cf033c4fa08562d5c 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 68 79 1.3E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c15020 f8243346bd3d7c8cf033c4fa08562d5c 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 1.3E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c15020 f8243346bd3d7c8cf033c4fa08562d5c 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 197 217 1.3E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c15020 f8243346bd3d7c8cf033c4fa08562d5c 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 115 131 1.3E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c15020 f8243346bd3d7c8cf033c4fa08562d5c 235 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 233 1.4E-55 T 12-10-2018 MIM_c15020 f8243346bd3d7c8cf033c4fa08562d5c 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 68 79 2.9E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c15020 f8243346bd3d7c8cf033c4fa08562d5c 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 121 129 2.9E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c15020 f8243346bd3d7c8cf033c4fa08562d5c 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 2.9E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c15020 f8243346bd3d7c8cf033c4fa08562d5c 235 Gene3D G3DSA:3.40.50.720 1 235 3.9E-72 T 12-10-2018 MIM_c15020 f8243346bd3d7c8cf033c4fa08562d5c 235 SUPERFAMILY SSF51735 2 234 1.6E-72 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c06330 248065c12d0f341f23d5940aecdb6f7a 269 Gene3D G3DSA:3.40.50.300 5 251 3.6E-60 T 12-10-2018 MIM_c06330 248065c12d0f341f23d5940aecdb6f7a 269 SUPERFAMILY SSF52540 8 234 4.61E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c06330 248065c12d0f341f23d5940aecdb6f7a 269 Pfam PF00005 ABC transporter 29 167 3.0E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c06330 248065c12d0f341f23d5940aecdb6f7a 269 SMART SM00382 37 217 8.1E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c06330 248065c12d0f341f23d5940aecdb6f7a 269 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 PRINTS PR00397 Sirohaem Fe-binding site signature 680 698 5.1E-7 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 PRINTS PR00397 Sirohaem Fe-binding site signature 637 655 5.1E-7 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 SUPERFAMILY SSF56014 634 799 3.14E-50 T 12-10-2018 MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 SUPERFAMILY SSF55124 520 642 8.58E-23 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 Gene3D G3DSA:3.30.413.10 637 799 2.4E-36 T 12-10-2018 MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 281 1.8E-11 T 12-10-2018 MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 1.8E-11 T 12-10-2018 MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.8E-11 T 12-10-2018 MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 1.8E-11 T 12-10-2018 MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 Gene3D G3DSA:3.50.50.60 7 290 9.3E-90 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 Gene3D G3DSA:3.30.390.30 318 397 1.2E-7 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 633 770 8.9E-28 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 SUPERFAMILY SSF51905 2 193 1.13E-43 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 283 9.3E-52 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 563 625 2.6E-13 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 Gene3D G3DSA:3.50.50.60 115 241 9.3E-90 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 6 798 1.7E-280 T 12-10-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 Pfam PF04324 BFD-like [2Fe-2S] binding domain 487 537 4.2E-15 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 Pfam PF04324 BFD-like [2Fe-2S] binding domain 423 471 1.2E-13 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 Gene3D G3DSA:3.90.480.10 566 636 3.2E-5 T 12-10-2018 MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 Gene3D G3DSA:1.10.10.1100 422 475 3.7E-8 T 12-10-2018 MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 6.2E-21 T 12-10-2018 MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 6.2E-21 T 12-10-2018 MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 6.2E-21 T 12-10-2018 MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 6.2E-21 T 12-10-2018 MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 6.2E-21 T 12-10-2018 MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 SUPERFAMILY SSF51905 144 308 4.0E-29 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 PIRSF PIRSF037149 1 808 0.0 T 12-10-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 MIM_c09430 287579195e4f50f4ec16bcce9ebbfba6 810 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 680 696 - T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MIM_c13950 fdf46bd28e297ffe79068fb2b55a2d12 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 318 3.9E-64 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c13950 fdf46bd28e297ffe79068fb2b55a2d12 322 Gene3D G3DSA:3.40.190.10 126 247 9.3E-95 T 12-10-2018 MIM_c13950 fdf46bd28e297ffe79068fb2b55a2d12 322 PIRSF PIRSF017082 1 321 2.6E-62 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c13950 fdf46bd28e297ffe79068fb2b55a2d12 322 Gene3D G3DSA:3.40.190.150 28 312 9.3E-95 T 12-10-2018 MIM_c13950 fdf46bd28e297ffe79068fb2b55a2d12 322 SUPERFAMILY SSF53850 104 285 5.6E-11 T 12-10-2018 MIM_c08590 941eb982b3de5764c399396c1f339970 543 Pfam PF00501 AMP-binding enzyme 13 435 3.9E-97 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MIM_c08590 941eb982b3de5764c399396c1f339970 543 Pfam PF13193 AMP-binding enzyme C-terminal domain 444 513 5.2E-16 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MIM_c08590 941eb982b3de5764c399396c1f339970 543 Gene3D G3DSA:3.30.300.310 432 535 1.6E-25 T 12-10-2018 MIM_c08590 941eb982b3de5764c399396c1f339970 543 ProSitePatterns PS00455 Putative AMP-binding domain signature. 189 200 - T 12-10-2018 IPR020845 AMP-binding, conserved site MIM_c08590 941eb982b3de5764c399396c1f339970 543 SUPERFAMILY SSF56801 7 534 1.57E-141 T 12-10-2018 MIM_c08590 941eb982b3de5764c399396c1f339970 543 Gene3D G3DSA:3.40.50.12780 2 431 1.7E-108 T 12-10-2018 MIM_c05860 50ffecdbd0d0a41adde765febea4b815 369 Gene3D G3DSA:3.20.20.70 4 356 2.5E-113 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c05860 50ffecdbd0d0a41adde765febea4b815 369 SUPERFAMILY SSF51395 2 356 9.58E-108 T 12-10-2018 MIM_c05860 50ffecdbd0d0a41adde765febea4b815 369 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 6 339 3.2E-63 T 12-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 MIM_c40070 b5ab2057204992367c7296f7bc43d480 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 3.4E-65 T 12-10-2018 IPR023798 Ribosomal protein S7 domain MIM_c40070 b5ab2057204992367c7296f7bc43d480 156 Gene3D G3DSA:1.10.455.10 2 156 7.6E-59 T 12-10-2018 IPR036823 Ribosomal protein S7 domain superfamily MIM_c40070 b5ab2057204992367c7296f7bc43d480 156 PIRSF PIRSF002122 3 156 8.0E-56 T 12-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 MIM_c40070 b5ab2057204992367c7296f7bc43d480 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 12-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c40070 b5ab2057204992367c7296f7bc43d480 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 2.3E-65 T 12-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 MIM_c40070 b5ab2057204992367c7296f7bc43d480 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.042 T 12-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 MIM_c40070 b5ab2057204992367c7296f7bc43d480 156 SUPERFAMILY SSF47973 2 149 1.96E-59 T 12-10-2018 IPR036823 Ribosomal protein S7 domain superfamily MIM_c14150 a12a60cfc5661d007c48f242ca93eb04 606 SMART SM00838 399 484 0.0012 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like MIM_c14150 a12a60cfc5661d007c48f242ca93eb04 606 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site MIM_c14150 a12a60cfc5661d007c48f242ca93eb04 606 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 138 1.7E-23 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MIM_c14150 a12a60cfc5661d007c48f242ca93eb04 606 PRINTS PR00315 GTP-binding elongation factor signature 71 81 7.7E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c14150 a12a60cfc5661d007c48f242ca93eb04 606 PRINTS PR00315 GTP-binding elongation factor signature 7 20 7.7E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c14150 a12a60cfc5661d007c48f242ca93eb04 606 PRINTS PR00315 GTP-binding elongation factor signature 87 98 7.7E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c14150 a12a60cfc5661d007c48f242ca93eb04 606 PRINTS PR00315 GTP-binding elongation factor signature 51 59 7.7E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c14150 a12a60cfc5661d007c48f242ca93eb04 606 PRINTS PR00315 GTP-binding elongation factor signature 123 132 7.7E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c14150 a12a60cfc5661d007c48f242ca93eb04 606 SUPERFAMILY SSF52540 5 219 1.3E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c14150 a12a60cfc5661d007c48f242ca93eb04 606 Gene3D G3DSA:2.40.30.10 199 300 7.1E-32 T 12-10-2018 MIM_c14150 a12a60cfc5661d007c48f242ca93eb04 606 Gene3D G3DSA:3.40.50.300 2 197 4.5E-65 T 12-10-2018 MIM_c14150 a12a60cfc5661d007c48f242ca93eb04 606 Pfam PF00009 Elongation factor Tu GTP binding domain 5 195 6.8E-55 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c14150 a12a60cfc5661d007c48f242ca93eb04 606 SUPERFAMILY SSF54980 303 388 2.21E-12 T 12-10-2018 IPR035647 EF-G domain III/V-like MIM_c14150 a12a60cfc5661d007c48f242ca93eb04 606 SUPERFAMILY SSF54980 399 514 1.15E-29 T 12-10-2018 IPR035647 EF-G domain III/V-like MIM_c14150 a12a60cfc5661d007c48f242ca93eb04 606 Gene3D G3DSA:3.30.70.870 307 591 5.7E-131 T 12-10-2018 MIM_c14150 a12a60cfc5661d007c48f242ca93eb04 606 SUPERFAMILY SSF50447 181 302 3.3E-27 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MIM_c14150 a12a60cfc5661d007c48f242ca93eb04 606 Gene3D G3DSA:2.40.50.250 484 600 5.7E-131 T 12-10-2018 MIM_c14150 a12a60cfc5661d007c48f242ca93eb04 606 Pfam PF00679 Elongation factor G C-terminus 398 478 1.6E-23 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like MIM_c14150 a12a60cfc5661d007c48f242ca93eb04 606 Pfam PF03144 Elongation factor Tu domain 2 219 290 2.7E-12 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MIM_c14150 a12a60cfc5661d007c48f242ca93eb04 606 Gene3D G3DSA:3.30.70.240 390 483 5.7E-131 T 12-10-2018 MIM_c14150 a12a60cfc5661d007c48f242ca93eb04 606 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 5 600 1.8E-290 T 12-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 MIM_c39550 6d812c0a6726dae271cdae04ade6784f 313 SUPERFAMILY SSF53613 1 305 1.31E-84 T 12-10-2018 IPR029056 Ribokinase-like MIM_c39550 6d812c0a6726dae271cdae04ade6784f 313 Gene3D G3DSA:3.40.1190.20 3 312 5.5E-89 T 12-10-2018 IPR029056 Ribokinase-like MIM_c39550 6d812c0a6726dae271cdae04ade6784f 313 PRINTS PR00990 Ribokinase signature 186 201 9.1E-5 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MIM_c39550 6d812c0a6726dae271cdae04ade6784f 313 PRINTS PR00990 Ribokinase signature 225 236 9.1E-5 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MIM_c39550 6d812c0a6726dae271cdae04ade6784f 313 PRINTS PR00990 Ribokinase signature 30 49 9.1E-5 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MIM_c39550 6d812c0a6726dae271cdae04ade6784f 313 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 255 268 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MIM_c39550 6d812c0a6726dae271cdae04ade6784f 313 Pfam PF00294 pfkB family carbohydrate kinase 5 302 2.7E-61 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB MIM_c09850 d050dd9b1ce4f76dcc4bca65a18bb9f5 916 Gene3D G3DSA:3.90.1440.10 228 368 1.1E-174 T 12-10-2018 MIM_c09850 d050dd9b1ce4f76dcc4bca65a18bb9f5 916 SUPERFAMILY SSF81767 226 368 1.57E-41 T 12-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 MIM_c09850 d050dd9b1ce4f76dcc4bca65a18bb9f5 916 Gene3D G3DSA:3.40.50.300 21 415 1.1E-174 T 12-10-2018 MIM_c09850 d050dd9b1ce4f76dcc4bca65a18bb9f5 916 Pfam PF07517 SecA DEAD-like domain 5 402 2.2E-130 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 MIM_c09850 d050dd9b1ce4f76dcc4bca65a18bb9f5 916 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 27 823 0.0 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MIM_c09850 d050dd9b1ce4f76dcc4bca65a18bb9f5 916 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 838 19.748 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MIM_c09850 d050dd9b1ce4f76dcc4bca65a18bb9f5 916 Pfam PF01043 SecA preprotein cross-linking domain 231 358 1.8E-35 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 MIM_c09850 d050dd9b1ce4f76dcc4bca65a18bb9f5 916 ProSitePatterns PS01312 SecA family signature. 500 515 - T 12-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 MIM_c09850 d050dd9b1ce4f76dcc4bca65a18bb9f5 916 Pfam PF02810 SEC-C motif 896 914 1.8E-10 T 12-10-2018 IPR004027 SEC-C motif MIM_c09850 d050dd9b1ce4f76dcc4bca65a18bb9f5 916 Gene3D G3DSA:1.10.3060.10 627 839 2.1E-73 T 12-10-2018 MIM_c09850 d050dd9b1ce4f76dcc4bca65a18bb9f5 916 SUPERFAMILY SSF52540 417 620 7.16E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c09850 d050dd9b1ce4f76dcc4bca65a18bb9f5 916 PRINTS PR00906 SecA protein signature 116 126 2.6E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MIM_c09850 d050dd9b1ce4f76dcc4bca65a18bb9f5 916 PRINTS PR00906 SecA protein signature 62 86 2.6E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MIM_c09850 d050dd9b1ce4f76dcc4bca65a18bb9f5 916 PRINTS PR00906 SecA protein signature 339 361 2.6E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MIM_c09850 d050dd9b1ce4f76dcc4bca65a18bb9f5 916 PRINTS PR00906 SecA protein signature 100 114 2.6E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MIM_c09850 d050dd9b1ce4f76dcc4bca65a18bb9f5 916 PRINTS PR00906 SecA protein signature 413 426 2.6E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MIM_c09850 d050dd9b1ce4f76dcc4bca65a18bb9f5 916 PRINTS PR00906 SecA protein signature 169 189 2.6E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MIM_c09850 d050dd9b1ce4f76dcc4bca65a18bb9f5 916 PRINTS PR00906 SecA protein signature 376 393 2.6E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MIM_c09850 d050dd9b1ce4f76dcc4bca65a18bb9f5 916 Pfam PF07516 SecA Wing and Scaffold domain 623 836 1.8E-64 T 12-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 MIM_c09850 d050dd9b1ce4f76dcc4bca65a18bb9f5 916 SUPERFAMILY SSF52540 4 415 1.1E-83 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c09850 d050dd9b1ce4f76dcc4bca65a18bb9f5 916 Gene3D G3DSA:3.40.50.300 417 626 6.2E-85 T 12-10-2018 MIM_c09850 d050dd9b1ce4f76dcc4bca65a18bb9f5 916 SMART SM00957 5 402 1.1E-294 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 MIM_c09850 d050dd9b1ce4f76dcc4bca65a18bb9f5 916 SUPERFAMILY SSF81886 627 904 7.98E-80 T 12-10-2018 IPR036266 SecA, Wing/Scaffold superfamily MIM_c09850 d050dd9b1ce4f76dcc4bca65a18bb9f5 916 SMART SM00958 227 358 6.7E-73 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 MIM_c09850 d050dd9b1ce4f76dcc4bca65a18bb9f5 916 Gene3D G3DSA:3.10.450.50 843 915 1.0E-8 T 12-10-2018 MIM_c17880 9767f119a86d63b8f696b577ecc179d7 433 Pfam PF04551 GcpE protein 30 410 7.1E-113 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MIM_c17880 9767f119a86d63b8f696b577ecc179d7 433 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 18 412 27.936 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MIM_c17880 9767f119a86d63b8f696b577ecc179d7 433 PIRSF PIRSF004640 11 420 1.6E-126 T 12-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MIM_c17880 9767f119a86d63b8f696b577ecc179d7 433 SUPERFAMILY SSF56014 309 416 2.27E-7 T 12-10-2018 MIM_c17880 9767f119a86d63b8f696b577ecc179d7 433 Gene3D G3DSA:3.20.20.20 13 303 2.7E-93 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MIM_c17880 9767f119a86d63b8f696b577ecc179d7 433 Gene3D G3DSA:3.30.413.10 304 421 3.0E-38 T 12-10-2018 MIM_c17880 9767f119a86d63b8f696b577ecc179d7 433 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 17 409 7.9E-115 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MIM_c18130 76e64b95dc4b6d4c75df8034c3625d18 72 Gene3D G3DSA:1.20.58.660 1 72 2.5E-24 T 12-10-2018 MIM_c18130 76e64b95dc4b6d4c75df8034c3625d18 72 Pfam PF04325 Protein of unknown function (DUF465) 19 66 5.1E-11 T 12-10-2018 IPR007420 Protein of unknown function DUF465 MIM_c40520 5eed64bc992b435c951ccdc012619bde 326 Gene3D G3DSA:3.40.190.10 126 249 6.9E-104 T 12-10-2018 MIM_c40520 5eed64bc992b435c951ccdc012619bde 326 Gene3D G3DSA:3.40.190.150 28 319 6.9E-104 T 12-10-2018 MIM_c40520 5eed64bc992b435c951ccdc012619bde 326 SUPERFAMILY SSF53850 113 285 1.63E-9 T 12-10-2018 MIM_c40520 5eed64bc992b435c951ccdc012619bde 326 PIRSF PIRSF017082 1 326 1.5E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c40520 5eed64bc992b435c951ccdc012619bde 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 323 1.8E-72 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c09130 35a0ed4e34dccc696af420fef5f15617 369 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 160 255 1.8E-19 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c09130 35a0ed4e34dccc696af420fef5f15617 369 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 177 361 8.8E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c09130 35a0ed4e34dccc696af420fef5f15617 369 SUPERFAMILY SSF161098 157 354 2.88E-41 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c09130 35a0ed4e34dccc696af420fef5f15617 369 Gene3D G3DSA:1.10.3720.10 148 366 2.4E-48 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c25830 23eb15f6ffbe04b4e576db7390fa0d81 728 Gene3D G3DSA:2.170.130.10 64 193 1.9E-33 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MIM_c25830 23eb15f6ffbe04b4e576db7390fa0d81 728 Gene3D G3DSA:2.40.170.20 194 728 6.3E-142 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MIM_c25830 23eb15f6ffbe04b4e576db7390fa0d81 728 SUPERFAMILY SSF56935 75 728 1.1E-114 T 12-10-2018 MIM_c25830 23eb15f6ffbe04b4e576db7390fa0d81 728 Pfam PF00593 TonB dependent receptor 289 727 6.7E-43 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MIM_c25830 23eb15f6ffbe04b4e576db7390fa0d81 728 Pfam PF07715 TonB-dependent Receptor Plug Domain 86 186 4.3E-15 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain MIM_c25830 23eb15f6ffbe04b4e576db7390fa0d81 728 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 88 727 4.8E-106 T 12-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 MIM_c40290 f2ba14d0f3288328d41c9cbe9cac66ef 238 SMART SM00895 86 215 8.6E-15 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c40290 f2ba14d0f3288328d41c9cbe9cac66ef 238 SMART SM00345 18 76 1.6E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c40290 f2ba14d0f3288328d41c9cbe9cac66ef 238 SUPERFAMILY SSF48008 82 221 4.71E-22 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c40290 f2ba14d0f3288328d41c9cbe9cac66ef 238 Pfam PF07729 FCD domain 86 211 1.9E-21 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c40290 f2ba14d0f3288328d41c9cbe9cac66ef 238 SUPERFAMILY SSF46785 8 85 1.23E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c40290 f2ba14d0f3288328d41c9cbe9cac66ef 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 76 2.4E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c40290 f2ba14d0f3288328d41c9cbe9cac66ef 238 Gene3D G3DSA:1.20.120.530 81 223 9.6E-27 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c40290 f2ba14d0f3288328d41c9cbe9cac66ef 238 Gene3D G3DSA:1.10.10.10 5 76 5.8E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c23600 267038f7a5b25a2ad9e8516906e1ff04 548 Gene3D G3DSA:3.50.50.60 8 385 4.5E-198 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c23600 267038f7a5b25a2ad9e8516906e1ff04 548 Gene3D G3DSA:3.30.9.90 80 448 4.5E-198 T 12-10-2018 MIM_c23600 267038f7a5b25a2ad9e8516906e1ff04 548 Gene3D G3DSA:3.30.70.20 449 543 7.1E-40 T 12-10-2018 MIM_c23600 267038f7a5b25a2ad9e8516906e1ff04 548 SUPERFAMILY SSF54862 448 546 1.38E-28 T 12-10-2018 MIM_c23600 267038f7a5b25a2ad9e8516906e1ff04 548 Pfam PF13450 NAD(P)-binding Rossmann-like domain 13 58 4.1E-6 T 12-10-2018 MIM_c23600 267038f7a5b25a2ad9e8516906e1ff04 548 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 444 546 2.9E-50 T 12-10-2018 MIM_c23600 267038f7a5b25a2ad9e8516906e1ff04 548 SUPERFAMILY SSF54373 212 306 4.32E-38 T 12-10-2018 MIM_c23600 267038f7a5b25a2ad9e8516906e1ff04 548 SUPERFAMILY SSF51905 3 446 2.55E-55 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c01380 6a1b93c11d98695925adba6b34e36aaf 355 SUPERFAMILY SSF89733 8 348 2.35E-102 T 12-10-2018 IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily GO:0016491|GO:0055114 MIM_c01380 6a1b93c11d98695925adba6b34e36aaf 355 Gene3D G3DSA:3.30.1370.60 73 322 2.6E-118 T 12-10-2018 MIM_c01380 6a1b93c11d98695925adba6b34e36aaf 355 Gene3D G3DSA:1.10.1530.10 15 343 2.6E-118 T 12-10-2018 MIM_c01380 6a1b93c11d98695925adba6b34e36aaf 355 Pfam PF02615 Malate/L-lactate dehydrogenase 9 339 2.0E-112 T 12-10-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0016491|GO:0055114 MIM_c17020 bb1adfcf991d0fbea32a06a18f117d88 298 Pfam PF13560 Helix-turn-helix domain 26 105 9.3E-16 T 12-10-2018 MIM_c17020 bb1adfcf991d0fbea32a06a18f117d88 298 Gene3D G3DSA:3.30.450.180 128 296 4.4E-9 T 12-10-2018 MIM_c17020 bb1adfcf991d0fbea32a06a18f117d88 298 SMART SM00530 30 102 2.8E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c17020 bb1adfcf991d0fbea32a06a18f117d88 298 SUPERFAMILY SSF47413 25 100 6.52E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c17020 bb1adfcf991d0fbea32a06a18f117d88 298 Gene3D G3DSA:1.10.260.40 41 119 4.0E-5 T 12-10-2018 MIM_c17190 a1c224e915c31aefe3324933f75989c8 472 SUPERFAMILY SSF55874 304 467 1.7E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c17190 a1c224e915c31aefe3324933f75989c8 472 Pfam PF00672 HAMP domain 198 243 2.4E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MIM_c17190 a1c224e915c31aefe3324933f75989c8 472 SMART SM00387 359 469 1.0E-25 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c17190 a1c224e915c31aefe3324933f75989c8 472 Gene3D G3DSA:3.30.565.10 324 470 2.7E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c17190 a1c224e915c31aefe3324933f75989c8 472 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 359 464 6.3E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c17190 a1c224e915c31aefe3324933f75989c8 472 Gene3D G3DSA:1.10.287.130 198 314 5.3E-21 T 12-10-2018 MIM_c17190 a1c224e915c31aefe3324933f75989c8 472 SUPERFAMILY SSF158472 196 245 1.96E-6 T 12-10-2018 MIM_c17190 a1c224e915c31aefe3324933f75989c8 472 Pfam PF00512 His Kinase A (phospho-acceptor) domain 255 314 3.4E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MIM_c17190 a1c224e915c31aefe3324933f75989c8 472 SUPERFAMILY SSF47384 231 314 8.44E-13 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MIM_c17190 a1c224e915c31aefe3324933f75989c8 472 SMART SM00304 194 247 1.2E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MIM_c17190 a1c224e915c31aefe3324933f75989c8 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 408 1.2E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c17190 a1c224e915c31aefe3324933f75989c8 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 425 443 1.2E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c17190 a1c224e915c31aefe3324933f75989c8 472 SMART SM00388 248 314 3.7E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MIM_c22550 737c8b310b10b993fb3f0f1b2eff7f2c 171 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 11 159 22.163 T 12-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MIM_c22550 737c8b310b10b993fb3f0f1b2eff7f2c 171 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 17 154 5.7E-34 T 12-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MIM_c22550 737c8b310b10b993fb3f0f1b2eff7f2c 171 Gene3D G3DSA:3.40.50.960 7 161 7.1E-46 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MIM_c22550 737c8b310b10b993fb3f0f1b2eff7f2c 171 SUPERFAMILY SSF52121 9 159 1.15E-42 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MIM_c03550 8d80ae2e54e535e23d08576c310e9b12 120 Pfam PF08895 Domain of unknown function (DUF1840) 1 114 5.6E-31 T 12-10-2018 IPR014991 Protein of unknown function DUF1840 MIM_c25890 abb46652b3c33822ce2384f3226b043e 143 Pfam PF13411 MerR HTH family regulatory protein 1 67 3.9E-20 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MIM_c25890 abb46652b3c33822ce2384f3226b043e 143 SUPERFAMILY SSF46955 1 126 3.52E-35 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily MIM_c25890 abb46652b3c33822ce2384f3226b043e 143 TIGRFAM TIGR02047 CadR-PbrR: Cd(II)/Pb(II)-responsive transcriptional regulator 1 127 9.3E-51 T 12-10-2018 IPR011791 Cd(II)/Pb(II)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0045893|GO:0046872 MIM_c25890 abb46652b3c33822ce2384f3226b043e 143 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 6.7E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MIM_c25890 abb46652b3c33822ce2384f3226b043e 143 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 6.7E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MIM_c25890 abb46652b3c33822ce2384f3226b043e 143 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 6.7E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MIM_c25890 abb46652b3c33822ce2384f3226b043e 143 Gene3D G3DSA:1.10.1660.10 1 126 1.6E-34 T 12-10-2018 MIM_c25890 abb46652b3c33822ce2384f3226b043e 143 SMART SM00422 1 70 4.5E-28 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MIM_c06350 294b757e5cbb107fdcda638f35a9aacc 363 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 MIM_c06350 294b757e5cbb107fdcda638f35a9aacc 363 SMART SM01329 6 355 1.8E-185 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MIM_c06350 294b757e5cbb107fdcda638f35a9aacc 363 Gene3D G3DSA:3.40.718.10 1 361 4.4E-146 T 12-10-2018 MIM_c06350 294b757e5cbb107fdcda638f35a9aacc 363 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 3 357 2.7E-172 T 12-10-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 MIM_c06350 294b757e5cbb107fdcda638f35a9aacc 363 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 6 355 1.2E-89 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MIM_c06350 294b757e5cbb107fdcda638f35a9aacc 363 SUPERFAMILY SSF53659 3 357 1.32E-118 T 12-10-2018 MIM_c04370 87334409a4ebfab50fc00e09521aed6a 472 Gene3D G3DSA:3.30.499.10 305 472 1.1E-46 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 MIM_c04370 87334409a4ebfab50fc00e09521aed6a 472 Pfam PF00330 Aconitase family (aconitate hydratase) 9 459 9.4E-137 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c04370 87334409a4ebfab50fc00e09521aed6a 472 ProSitePatterns PS01244 Aconitase family signature 2. 401 414 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MIM_c04370 87334409a4ebfab50fc00e09521aed6a 472 SUPERFAMILY SSF53732 5 467 1.57E-146 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 MIM_c04370 87334409a4ebfab50fc00e09521aed6a 472 PRINTS PR00415 Aconitase family signature 401 414 6.8E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c04370 87334409a4ebfab50fc00e09521aed6a 472 PRINTS PR00415 Aconitase family signature 197 210 6.8E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c04370 87334409a4ebfab50fc00e09521aed6a 472 PRINTS PR00415 Aconitase family signature 211 224 6.8E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c04370 87334409a4ebfab50fc00e09521aed6a 472 PRINTS PR00415 Aconitase family signature 110 118 6.8E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c04370 87334409a4ebfab50fc00e09521aed6a 472 PRINTS PR00415 Aconitase family signature 135 150 6.8E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c04370 87334409a4ebfab50fc00e09521aed6a 472 PRINTS PR00415 Aconitase family signature 121 134 6.8E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c04370 87334409a4ebfab50fc00e09521aed6a 472 PRINTS PR00415 Aconitase family signature 345 356 6.8E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c04370 87334409a4ebfab50fc00e09521aed6a 472 PRINTS PR00415 Aconitase family signature 288 302 6.8E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c04370 87334409a4ebfab50fc00e09521aed6a 472 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 4 465 7.2E-179 T 12-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 MIM_c04370 87334409a4ebfab50fc00e09521aed6a 472 Gene3D G3DSA:3.30.499.20 13 288 2.8E-82 T 12-10-2018 MIM_c01470 f3c4a0788bf0d06add635cddd6204cf1 327 Pfam PF00753 Metallo-beta-lactamase superfamily 92 279 2.0E-22 T 12-10-2018 IPR001279 Metallo-beta-lactamase MIM_c01470 f3c4a0788bf0d06add635cddd6204cf1 327 Gene3D G3DSA:3.60.15.10 33 326 1.1E-87 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MIM_c01470 f3c4a0788bf0d06add635cddd6204cf1 327 SMART SM00849 92 297 6.3E-18 T 12-10-2018 IPR001279 Metallo-beta-lactamase MIM_c01470 f3c4a0788bf0d06add635cddd6204cf1 327 SUPERFAMILY SSF56281 37 308 1.24E-44 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MIM_c12400 02862084dd5d5150bcac962e959e7c43 279 SUPERFAMILY SSF82689 171 265 1.44E-17 T 12-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MIM_c12400 02862084dd5d5150bcac962e959e7c43 279 SUPERFAMILY SSF82861 18 102 2.09E-18 T 12-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 MIM_c12400 02862084dd5d5150bcac962e959e7c43 279 Pfam PF05552 Conserved TM helix 7 48 7.2E-7 T 12-10-2018 IPR008910 Conserved TM helix MIM_c12400 02862084dd5d5150bcac962e959e7c43 279 Pfam PF00924 Mechanosensitive ion channel 67 258 6.0E-45 T 12-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MIM_c12400 02862084dd5d5150bcac962e959e7c43 279 Gene3D G3DSA:3.30.70.100 170 263 7.9E-15 T 12-10-2018 MIM_c12400 02862084dd5d5150bcac962e959e7c43 279 SUPERFAMILY SSF50182 104 170 1.05E-14 T 12-10-2018 IPR010920 LSM domain superfamily MIM_c12400 02862084dd5d5150bcac962e959e7c43 279 Gene3D G3DSA:2.30.30.60 119 169 8.0E-14 T 12-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily MIM_c30200 552babdaeae92f6ba6bb6ca70b608a97 332 Gene3D G3DSA:3.40.190.10 133 257 1.6E-107 T 12-10-2018 MIM_c30200 552babdaeae92f6ba6bb6ca70b608a97 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 328 1.6E-90 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c30200 552babdaeae92f6ba6bb6ca70b608a97 332 PIRSF PIRSF017082 1 332 7.4E-84 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c30200 552babdaeae92f6ba6bb6ca70b608a97 332 SUPERFAMILY SSF53850 120 294 1.88E-12 T 12-10-2018 MIM_c30200 552babdaeae92f6ba6bb6ca70b608a97 332 Gene3D G3DSA:3.40.190.150 36 322 1.6E-107 T 12-10-2018 MIM_c06870 0f36a573185f80040b6e5dffb2752720 377 Pfam PF13439 Glycosyltransferase Family 4 15 173 3.6E-17 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MIM_c06870 0f36a573185f80040b6e5dffb2752720 377 SUPERFAMILY SSF53756 2 369 1.12E-70 T 12-10-2018 MIM_c06870 0f36a573185f80040b6e5dffb2752720 377 Gene3D G3DSA:3.40.50.2000 184 352 1.1E-32 T 12-10-2018 MIM_c06870 0f36a573185f80040b6e5dffb2752720 377 Gene3D G3DSA:3.40.50.2000 1 183 2.0E-26 T 12-10-2018 MIM_c06870 0f36a573185f80040b6e5dffb2752720 377 Pfam PF00534 Glycosyl transferases group 1 194 346 7.4E-28 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 MIM_c33080 0e9ed50df98bfede8a563483e4e6a1ee 177 Pfam PF02417 Chromate transporter 5 168 4.6E-33 T 12-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 MIM_c00890 de63258da024bfa979c33c5dde0823c2 325 SUPERFAMILY SSF46785 26 138 4.41E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c00890 de63258da024bfa979c33c5dde0823c2 325 Gene3D G3DSA:1.10.10.10 28 115 7.8E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c00890 de63258da024bfa979c33c5dde0823c2 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 3.5E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c00890 de63258da024bfa979c33c5dde0823c2 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 67 78 3.5E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c00890 de63258da024bfa979c33c5dde0823c2 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 57 67 3.5E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c00890 de63258da024bfa979c33c5dde0823c2 325 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 31 89 1.3E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c00890 de63258da024bfa979c33c5dde0823c2 325 SUPERFAMILY SSF53850 117 317 5.43E-36 T 12-10-2018 MIM_c00890 de63258da024bfa979c33c5dde0823c2 325 Pfam PF03466 LysR substrate binding domain 116 312 3.2E-31 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c00890 de63258da024bfa979c33c5dde0823c2 325 Gene3D G3DSA:3.40.190.290 118 314 8.8E-39 T 12-10-2018 MIM_c28300 377581de150d5e96e064fa74d1af47d9 521 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 119 519 3.2E-143 T 12-10-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 MIM_c28300 377581de150d5e96e064fa74d1af47d9 521 Pfam PF08666 SAF domain 22 92 2.7E-8 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 MIM_c28300 377581de150d5e96e064fa74d1af47d9 521 SMART SM00858 22 92 2.2E-10 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 MIM_c28300 377581de150d5e96e064fa74d1af47d9 521 TIGRFAM TIGR03248 galactar-dH20: galactarate dehydratase 14 521 9.0E-266 T 12-10-2018 IPR017654 Galactarate dehydratase GarD-like GO:0008867|GO:0046392 KEGG: 00053+4.2.1.42|MetaCyc: PWY-6497 MIM_c28300 377581de150d5e96e064fa74d1af47d9 521 Gene3D G3DSA:3.90.1210.30 14 91 1.8E-23 T 12-10-2018 MIM_c07110 beb39a25199e5ea07d3ac62785558e2b 191 Pfam PF03358 NADPH-dependent FMN reductase 6 150 4.7E-38 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 MIM_c07110 beb39a25199e5ea07d3ac62785558e2b 191 SUPERFAMILY SSF52218 6 178 3.11E-46 T 12-10-2018 IPR029039 Flavoprotein-like superfamily MIM_c07110 beb39a25199e5ea07d3ac62785558e2b 191 Gene3D G3DSA:3.40.50.360 1 190 3.2E-58 T 12-10-2018 IPR029039 Flavoprotein-like superfamily MIM_c26910 b442e05ac5f3055db5d2199418969077 173 Gene3D G3DSA:2.30.110.10 1 169 1.3E-41 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MIM_c26910 b442e05ac5f3055db5d2199418969077 173 SMART SM00903 17 166 3.9E-45 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MIM_c26910 b442e05ac5f3055db5d2199418969077 173 Pfam PF01613 Flavin reductase like domain 18 164 7.4E-31 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MIM_c26910 b442e05ac5f3055db5d2199418969077 173 SUPERFAMILY SSF50475 9 164 4.49E-39 T 12-10-2018 MIM_c40210 3b50c765c35563d39c574a8f8a70e367 457 Gene3D G3DSA:1.10.275.10 4 131 4.6E-48 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal MIM_c40210 3b50c765c35563d39c574a8f8a70e367 457 Hamap MF_00743 Fumarate hydratase class II [fumC]. 3 455 73.875 T 12-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MIM_c40210 3b50c765c35563d39c574a8f8a70e367 457 PRINTS PR00145 Argininosuccinate lyase family signature 126 148 2.9E-5 T 12-10-2018 MIM_c40210 3b50c765c35563d39c574a8f8a70e367 457 PRINTS PR00145 Argininosuccinate lyase family signature 168 188 2.9E-5 T 12-10-2018 MIM_c40210 3b50c765c35563d39c574a8f8a70e367 457 PRINTS PR00145 Argininosuccinate lyase family signature 310 326 2.9E-5 T 12-10-2018 MIM_c40210 3b50c765c35563d39c574a8f8a70e367 457 PRINTS PR00149 Fumarate lyase superfamily signature 310 326 6.6E-27 T 12-10-2018 IPR000362 Fumarate lyase family MIM_c40210 3b50c765c35563d39c574a8f8a70e367 457 PRINTS PR00149 Fumarate lyase superfamily signature 264 291 6.6E-27 T 12-10-2018 IPR000362 Fumarate lyase family MIM_c40210 3b50c765c35563d39c574a8f8a70e367 457 PRINTS PR00149 Fumarate lyase superfamily signature 173 191 6.6E-27 T 12-10-2018 IPR000362 Fumarate lyase family MIM_c40210 3b50c765c35563d39c574a8f8a70e367 457 PRINTS PR00149 Fumarate lyase superfamily signature 127 145 6.6E-27 T 12-10-2018 IPR000362 Fumarate lyase family MIM_c40210 3b50c765c35563d39c574a8f8a70e367 457 SUPERFAMILY SSF48557 3 453 1.41E-133 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 MIM_c40210 3b50c765c35563d39c574a8f8a70e367 457 Pfam PF00206 Lyase 11 335 1.4E-91 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal MIM_c40210 3b50c765c35563d39c574a8f8a70e367 457 ProSitePatterns PS00163 Fumarate lyases signature. 310 319 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MIM_c40210 3b50c765c35563d39c574a8f8a70e367 457 Gene3D G3DSA:1.20.200.10 132 398 9.2E-97 T 12-10-2018 MIM_c40210 3b50c765c35563d39c574a8f8a70e367 457 Gene3D G3DSA:1.10.40.30 401 456 4.3E-18 T 12-10-2018 MIM_c40210 3b50c765c35563d39c574a8f8a70e367 457 Pfam PF10415 Fumarase C C-terminus 401 453 4.7E-18 T 12-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MIM_c34720 b64bb7bfc54a2ec626f4e3ef474f7f0a 320 PIRSF PIRSF017082 1 319 5.6E-82 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c34720 b64bb7bfc54a2ec626f4e3ef474f7f0a 320 SUPERFAMILY SSF53850 108 282 1.72E-16 T 12-10-2018 MIM_c34720 b64bb7bfc54a2ec626f4e3ef474f7f0a 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 44 316 2.6E-84 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c34720 b64bb7bfc54a2ec626f4e3ef474f7f0a 320 Gene3D G3DSA:3.40.190.150 24 309 4.8E-109 T 12-10-2018 MIM_c34720 b64bb7bfc54a2ec626f4e3ef474f7f0a 320 Gene3D G3DSA:3.40.190.10 122 245 4.8E-109 T 12-10-2018 MIM_c05800 4e5d2faab4a0cfa83971893e3dcad116 225 SUPERFAMILY SSF53335 10 188 1.59E-32 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c05800 4e5d2faab4a0cfa83971893e3dcad116 225 Gene3D G3DSA:3.40.50.150 3 223 2.0E-46 T 12-10-2018 MIM_c05800 4e5d2faab4a0cfa83971893e3dcad116 225 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 14 197 1.9E-36 T 12-10-2018 MIM_c21440 85491350fd5723d2cc28743288980998 214 Pfam PF02660 Glycerol-3-phosphate acyltransferase 17 200 2.1E-50 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MIM_c21440 85491350fd5723d2cc28743288980998 214 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 12 209 20.312 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MIM_c21440 85491350fd5723d2cc28743288980998 214 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 10 211 2.3E-61 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MIM_c21440 85491350fd5723d2cc28743288980998 214 SMART SM01207 15 201 5.3E-85 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MIM_c19630 a86bf995c141e3afdb23fc4d3d87ad21 218 Pfam PF12796 Ankyrin repeats (3 copies) 81 158 3.6E-14 T 12-10-2018 IPR020683 Ankyrin repeat-containing domain MIM_c19630 a86bf995c141e3afdb23fc4d3d87ad21 218 SUPERFAMILY SSF48403 35 215 3.66E-42 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily MIM_c19630 a86bf995c141e3afdb23fc4d3d87ad21 218 Gene3D G3DSA:1.25.40.20 12 218 2.1E-46 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily MIM_c19630 a86bf995c141e3afdb23fc4d3d87ad21 218 SMART SM00248 129 158 3.4E-6 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 MIM_c19630 a86bf995c141e3afdb23fc4d3d87ad21 218 SMART SM00248 65 95 1100.0 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 MIM_c19630 a86bf995c141e3afdb23fc4d3d87ad21 218 SMART SM00248 162 191 0.0039 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 MIM_c19630 a86bf995c141e3afdb23fc4d3d87ad21 218 SMART SM00248 99 128 1.6 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 MIM_c19630 a86bf995c141e3afdb23fc4d3d87ad21 218 PRINTS PR01415 Ankyrin repeat signature 178 192 2.2E-7 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 MIM_c19630 a86bf995c141e3afdb23fc4d3d87ad21 218 PRINTS PR01415 Ankyrin repeat signature 130 145 2.2E-7 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 MIM_c13670 6138b5c2586bcc7122421949a9b6cd3d 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 6.9E-22 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c13670 6138b5c2586bcc7122421949a9b6cd3d 300 Gene3D G3DSA:1.10.10.10 5 94 1.8E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c13670 6138b5c2586bcc7122421949a9b6cd3d 300 Gene3D G3DSA:3.40.190.290 95 295 1.9E-52 T 12-10-2018 MIM_c13670 6138b5c2586bcc7122421949a9b6cd3d 300 Pfam PF03466 LysR substrate binding domain 90 294 1.1E-38 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c13670 6138b5c2586bcc7122421949a9b6cd3d 300 SUPERFAMILY SSF53850 90 298 5.79E-41 T 12-10-2018 MIM_c13670 6138b5c2586bcc7122421949a9b6cd3d 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 5.1E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c13670 6138b5c2586bcc7122421949a9b6cd3d 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 5.1E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c13670 6138b5c2586bcc7122421949a9b6cd3d 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 5.1E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c13670 6138b5c2586bcc7122421949a9b6cd3d 300 SUPERFAMILY SSF46785 6 90 8.71E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c27680 a6b0c08dea94cbd81461c0af93f9ec2a 345 Gene3D G3DSA:3.40.50.11030 226 344 5.2E-16 T 12-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily MIM_c27680 a6b0c08dea94cbd81461c0af93f9ec2a 345 PIRSF PIRSF004930 1 345 2.0E-97 T 12-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 MIM_c27680 a6b0c08dea94cbd81461c0af93f9ec2a 345 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 15 223 4.9E-48 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 MIM_c27680 a6b0c08dea94cbd81461c0af93f9ec2a 345 Pfam PF03481 Putative GTP-binding controlling metal-binding 214 342 1.2E-19 T 12-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain MIM_c27680 a6b0c08dea94cbd81461c0af93f9ec2a 345 Pfam PF01300 Telomere recombination 23 212 1.9E-51 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 MIM_c27680 a6b0c08dea94cbd81461c0af93f9ec2a 345 Gene3D G3DSA:3.90.870.10 5 225 8.0E-74 T 12-10-2018 MIM_c27680 a6b0c08dea94cbd81461c0af93f9ec2a 345 SUPERFAMILY SSF55821 15 224 1.56E-54 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily MIM_c14100 0da12617adb37f328135ba11e90973cd 162 Pfam PF02576 RimP N-terminal domain 9 74 2.8E-18 T 12-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal MIM_c14100 0da12617adb37f328135ba11e90973cd 162 SUPERFAMILY SSF74942 75 155 3.27E-10 T 12-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily MIM_c14100 0da12617adb37f328135ba11e90973cd 162 Gene3D G3DSA:3.30.300.70 1 71 1.2E-11 T 12-10-2018 IPR035956 RimP, N-terminal domain superfamily MIM_c14100 0da12617adb37f328135ba11e90973cd 162 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 2 155 21.296 T 12-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 MIM_c14100 0da12617adb37f328135ba11e90973cd 162 SUPERFAMILY SSF75420 3 74 8.37E-16 T 12-10-2018 IPR035956 RimP, N-terminal domain superfamily MIM_c14100 0da12617adb37f328135ba11e90973cd 162 Pfam PF17384 RimP C-terminal SH3 domain 77 153 1.3E-10 T 12-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal MIM_c34250 7ba23ce461f425176b807101086c22da 368 Pfam PF06114 IrrE N-terminal-like domain 152 270 2.1E-22 T 12-10-2018 IPR010359 IrrE N-terminal-like domain MIM_c34250 7ba23ce461f425176b807101086c22da 368 Gene3D G3DSA:1.10.260.40 5 88 8.4E-13 T 12-10-2018 MIM_c34250 7ba23ce461f425176b807101086c22da 368 SMART SM00530 8 63 1.1E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c34250 7ba23ce461f425176b807101086c22da 368 SUPERFAMILY SSF47413 5 70 9.12E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c34250 7ba23ce461f425176b807101086c22da 368 Pfam PF01381 Helix-turn-helix 12 62 7.2E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c12830 b316dda55694a16ee24e0448b0974d0b 323 Pfam PF01497 Periplasmic binding protein 95 252 1.8E-15 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain MIM_c12830 b316dda55694a16ee24e0448b0974d0b 323 Gene3D G3DSA:3.40.50.1980 140 321 7.5E-66 T 12-10-2018 MIM_c12830 b316dda55694a16ee24e0448b0974d0b 323 Gene3D G3DSA:3.40.50.1980 24 139 1.3E-31 T 12-10-2018 MIM_c12830 b316dda55694a16ee24e0448b0974d0b 323 SUPERFAMILY SSF53807 24 304 1.3E-35 T 12-10-2018 MIM_c29170 ae5cbd448cf41c6f53fcf56303ce50e3 101 PIRSF PIRSF028744 1 99 1.2E-37 T 12-10-2018 IPR014056 Addiction module killer protein, predicted MIM_c29170 ae5cbd448cf41c6f53fcf56303ce50e3 101 TIGRFAM TIGR02683 upstrm_HI1419: putative addiction module killer protein 4 95 5.8E-37 T 12-10-2018 IPR014056 Addiction module killer protein, predicted MIM_c29170 ae5cbd448cf41c6f53fcf56303ce50e3 101 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 12 90 1.6E-7 T 12-10-2018 IPR009241 Toxin HigB-like MIM_c21330 4183a3e5475466dbb3aaea1fd7d4652e 241 SUPERFAMILY SSF55120 64 239 1.6E-38 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MIM_c21330 4183a3e5475466dbb3aaea1fd7d4652e 241 Gene3D G3DSA:3.10.290.10 1 55 6.9E-17 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MIM_c21330 4183a3e5475466dbb3aaea1fd7d4652e 241 Gene3D G3DSA:3.30.2350.10 60 240 6.2E-46 T 12-10-2018 MIM_c21330 4183a3e5475466dbb3aaea1fd7d4652e 241 Pfam PF01479 S4 domain 5 40 3.0E-7 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c21330 4183a3e5475466dbb3aaea1fd7d4652e 241 Pfam PF00849 RNA pseudouridylate synthase 65 204 1.3E-10 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MIM_c21330 4183a3e5475466dbb3aaea1fd7d4652e 241 SMART SM00363 4 60 1.1E-4 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c21330 4183a3e5475466dbb3aaea1fd7d4652e 241 SUPERFAMILY SSF55174 4 95 2.09E-13 T 12-10-2018 MIM_c21330 4183a3e5475466dbb3aaea1fd7d4652e 241 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 104 235 3.6E-39 T 12-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 MIM_c32110 c49c3a184ac6b67eaff21473003d1ec5 147 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 4 139 20.463 T 12-10-2018 IPR011605 NusB antitermination factor GO:0006353 MIM_c32110 c49c3a184ac6b67eaff21473003d1ec5 147 Gene3D G3DSA:1.10.940.10 1 142 7.3E-39 T 12-10-2018 IPR035926 NusB-like superfamily MIM_c32110 c49c3a184ac6b67eaff21473003d1ec5 147 SUPERFAMILY SSF48013 3 139 9.03E-35 T 12-10-2018 IPR035926 NusB-like superfamily MIM_c32110 c49c3a184ac6b67eaff21473003d1ec5 147 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 6 136 2.9E-35 T 12-10-2018 IPR011605 NusB antitermination factor GO:0006353 MIM_c32110 c49c3a184ac6b67eaff21473003d1ec5 147 Pfam PF01029 NusB family 7 135 3.2E-28 T 12-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MIM_c06060 8687e5e31fd43ed30e2ee22e6129e940 331 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 12 252 1.9E-87 T 12-10-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 MIM_c06060 8687e5e31fd43ed30e2ee22e6129e940 331 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 33 278 3.3E-67 T 12-10-2018 MIM_c06060 8687e5e31fd43ed30e2ee22e6129e940 331 Gene3D G3DSA:3.40.190.10 116 228 3.8E-95 T 12-10-2018 MIM_c06060 8687e5e31fd43ed30e2ee22e6129e940 331 TIGRFAM TIGR03431 PhnD: phosphonate ABC transporter, periplasmic phosphonate binding protein 8 290 1.1E-102 T 12-10-2018 IPR017797 Phosphonate ABC transporter, substrate-binding protein GO:0015716|GO:0043190 MIM_c06060 8687e5e31fd43ed30e2ee22e6129e940 331 SUPERFAMILY SSF53850 52 244 2.32E-40 T 12-10-2018 MIM_c06060 8687e5e31fd43ed30e2ee22e6129e940 331 Gene3D G3DSA:1.20.58.90 276 331 3.2E-19 T 12-10-2018 MIM_c06060 8687e5e31fd43ed30e2ee22e6129e940 331 Gene3D G3DSA:3.40.190.10 32 259 3.8E-95 T 12-10-2018 MIM_c02710 827c333e457c583e6bda22cf8c0c3439 423 Gene3D G3DSA:3.40.50.10540 24 407 5.9E-113 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c02710 827c333e457c583e6bda22cf8c0c3439 423 Pfam PF02515 CoA-transferase family III 25 394 5.0E-109 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 MIM_c02710 827c333e457c583e6bda22cf8c0c3439 423 SUPERFAMILY SSF89796 23 407 1.1E-115 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c02710 827c333e457c583e6bda22cf8c0c3439 423 Gene3D G3DSA:3.30.1540.10 248 345 5.9E-113 T 12-10-2018 MIM_c39710 6cf15db2718dbc21e9ea62933dd007e1 229 Gene3D G3DSA:2.40.50.620 42 102 8.9E-13 T 12-10-2018 MIM_c39710 6cf15db2718dbc21e9ea62933dd007e1 229 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 14 217 7.4E-83 T 12-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c39710 6cf15db2718dbc21e9ea62933dd007e1 229 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 12 221 37.348 T 12-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c39710 6cf15db2718dbc21e9ea62933dd007e1 229 Gene3D G3DSA:2.40.30.10 145 224 9.2E-17 T 12-10-2018 MIM_c39710 6cf15db2718dbc21e9ea62933dd007e1 229 SUPERFAMILY SSF50447 9 225 1.24E-76 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MIM_c39710 6cf15db2718dbc21e9ea62933dd007e1 229 Pfam PF00297 Ribosomal protein L3 75 196 9.7E-18 T 12-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c39710 6cf15db2718dbc21e9ea62933dd007e1 229 ProSitePatterns PS00474 Ribosomal protein L3 signature. 115 138 - T 12-10-2018 IPR019926 Ribosomal protein L3, conserved site MIM_c16800 e2fd1a5f5b270b0a0453be850cb80d68 392 SUPERFAMILY SSF53850 38 268 2.61E-38 T 12-10-2018 MIM_c16800 e2fd1a5f5b270b0a0453be850cb80d68 392 Gene3D G3DSA:3.40.190.10 36 126 1.1E-14 T 12-10-2018 MIM_c16800 e2fd1a5f5b270b0a0453be850cb80d68 392 Gene3D G3DSA:3.40.190.10 172 384 2.7E-38 T 12-10-2018 MIM_c16800 e2fd1a5f5b270b0a0453be850cb80d68 392 Pfam PF13379 NMT1-like family 34 271 1.2E-45 T 12-10-2018 MIM_c39140 9c9ba84a17aa46b504750e784f95d7f9 456 Gene3D G3DSA:3.90.1150.10 13 448 6.2E-163 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c39140 9c9ba84a17aa46b504750e784f95d7f9 456 PIRSF PIRSF000521 4 450 1.6E-31 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MIM_c39140 9c9ba84a17aa46b504750e784f95d7f9 456 SUPERFAMILY SSF53383 12 448 6.41E-120 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c39140 9c9ba84a17aa46b504750e784f95d7f9 456 Pfam PF00202 Aminotransferase class-III 30 447 1.6E-91 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MIM_c39140 9c9ba84a17aa46b504750e784f95d7f9 456 Gene3D G3DSA:3.40.640.10 66 345 6.2E-163 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c39140 9c9ba84a17aa46b504750e784f95d7f9 456 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 255 292 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MIM_c29260 38aad16b85d93a79b1af00a79a9df20f 122 Gene3D G3DSA:2.60.300.12 17 122 1.7E-34 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 MIM_c29260 38aad16b85d93a79b1af00a79a9df20f 122 Pfam PF01521 Iron-sulphur cluster biosynthesis 18 117 3.8E-20 T 12-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MIM_c29260 38aad16b85d93a79b1af00a79a9df20f 122 Hamap MF_01380 Iron-sulfur cluster insertion protein ErpA [erpA]. 1 122 37.365 T 12-10-2018 IPR023063 FeS cluster insertion protein ErpA GO:0097428 MIM_c29260 38aad16b85d93a79b1af00a79a9df20f 122 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 19 122 2.0E-38 T 12-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 MIM_c29260 38aad16b85d93a79b1af00a79a9df20f 122 SUPERFAMILY SSF89360 17 111 5.49E-31 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 MIM_c29260 38aad16b85d93a79b1af00a79a9df20f 122 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 103 120 - T 12-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 MIM_c06310 9db72e6bc39dbf5938e49b5f8d4b913c 165 Gene3D G3DSA:3.40.470.10 7 164 5.0E-50 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MIM_c06310 9db72e6bc39dbf5938e49b5f8d4b913c 165 SUPERFAMILY SSF52141 10 160 2.75E-27 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MIM_c06310 9db72e6bc39dbf5938e49b5f8d4b913c 165 TIGRFAM TIGR04274 hypoxanDNAglyco: DNA-deoxyinosine glycosylase 9 156 4.4E-45 T 12-10-2018 IPR026353 Hypoxanthine-DNA glycosylase MIM_c30750 f6f3f6270645d42e08d67430388a959a 353 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 110 311 9.9E-17 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase MIM_c30750 f6f3f6270645d42e08d67430388a959a 353 SUPERFAMILY SSF56219 99 319 3.8E-32 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MIM_c30750 f6f3f6270645d42e08d67430388a959a 353 Gene3D G3DSA:3.60.10.10 98 320 4.6E-21 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MIM_c33670 b5eca67cdaa3d815c3a2b1590f9fcf6f 314 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 245 312 2.2E-10 T 12-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MIM_c33670 b5eca67cdaa3d815c3a2b1590f9fcf6f 314 SUPERFAMILY SSF53901 152 313 2.72E-12 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c33670 b5eca67cdaa3d815c3a2b1590f9fcf6f 314 SUPERFAMILY SSF53901 46 165 3.72E-9 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c33670 b5eca67cdaa3d815c3a2b1590f9fcf6f 314 Gene3D G3DSA:3.40.47.10 170 313 3.4E-23 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c33670 b5eca67cdaa3d815c3a2b1590f9fcf6f 314 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 105 174 1.5E-5 T 12-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MIM_c33670 b5eca67cdaa3d815c3a2b1590f9fcf6f 314 Gene3D G3DSA:3.40.47.10 7 168 1.5E-28 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c32320 b5fa406a6ffa91df7b0f4a8f31e3e084 363 Pfam PF01926 50S ribosome-binding GTPase 5 121 1.7E-23 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 MIM_c32320 b5fa406a6ffa91df7b0f4a8f31e3e084 363 SUPERFAMILY SSF81271 279 359 1.11E-33 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MIM_c32320 b5fa406a6ffa91df7b0f4a8f31e3e084 363 Gene3D G3DSA:3.40.50.300 3 278 5.4E-147 T 12-10-2018 MIM_c32320 b5fa406a6ffa91df7b0f4a8f31e3e084 363 PIRSF PIRSF006641 1 363 2.9E-151 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 MIM_c32320 b5fa406a6ffa91df7b0f4a8f31e3e084 363 Pfam PF06071 Protein of unknown function (DUF933) 279 362 5.0E-37 T 12-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 MIM_c32320 b5fa406a6ffa91df7b0f4a8f31e3e084 363 Gene3D G3DSA:3.10.20.30 48 361 5.4E-147 T 12-10-2018 IPR012675 Beta-grasp domain superfamily MIM_c32320 b5fa406a6ffa91df7b0f4a8f31e3e084 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 1.5E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 MIM_c32320 b5fa406a6ffa91df7b0f4a8f31e3e084 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 1.5E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 MIM_c32320 b5fa406a6ffa91df7b0f4a8f31e3e084 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 1.5E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 MIM_c32320 b5fa406a6ffa91df7b0f4a8f31e3e084 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.5E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 MIM_c32320 b5fa406a6ffa91df7b0f4a8f31e3e084 363 Gene3D G3DSA:1.10.150.300 113 200 5.4E-147 T 12-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 MIM_c32320 b5fa406a6ffa91df7b0f4a8f31e3e084 363 SUPERFAMILY SSF52540 3 301 1.05E-83 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c32320 b5fa406a6ffa91df7b0f4a8f31e3e084 363 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 363 43.818 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 MIM_c32320 b5fa406a6ffa91df7b0f4a8f31e3e084 363 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 363 3.0E-154 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 MIM_c07770 4b2bc2033276184a655689fb258aeca5 176 Gene3D G3DSA:2.40.50.90 27 166 1.7E-31 T 12-10-2018 IPR035437 SNase-like, OB-fold superfamily MIM_c07770 4b2bc2033276184a655689fb258aeca5 176 SUPERFAMILY SSF50199 24 167 5.23E-35 T 12-10-2018 MIM_c07770 4b2bc2033276184a655689fb258aeca5 176 Pfam PF00565 Staphylococcal nuclease homologue 54 160 3.4E-24 T 12-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 MIM_c07770 4b2bc2033276184a655689fb258aeca5 176 ProSitePatterns PS01123 Thermonuclease family signature 1. 40 64 - T 12-10-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 MIM_c07770 4b2bc2033276184a655689fb258aeca5 176 ProSitePatterns PS01284 Thermonuclease family signature 2. 94 104 - T 12-10-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 MIM_c07770 4b2bc2033276184a655689fb258aeca5 176 SMART SM00318 29 160 3.1E-41 T 12-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 MIM_c24820 bd5fc0200a655e4cae809a98d89a7bc9 705 Gene3D G3DSA:3.40.50.261 304 466 9.8E-27 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c24820 bd5fc0200a655e4cae809a98d89a7bc9 705 Pfam PF13380 CoA binding domain 16 141 7.2E-20 T 12-10-2018 IPR003781 CoA-binding GO:0048037 MIM_c24820 bd5fc0200a655e4cae809a98d89a7bc9 705 Gene3D G3DSA:3.40.50.261 145 301 1.1E-37 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c24820 bd5fc0200a655e4cae809a98d89a7bc9 705 SMART SM00881 12 107 5.2E-31 T 12-10-2018 IPR003781 CoA-binding GO:0048037 MIM_c24820 bd5fc0200a655e4cae809a98d89a7bc9 705 Pfam PF13549 ATP-grasp domain 483 699 2.8E-49 T 12-10-2018 MIM_c24820 bd5fc0200a655e4cae809a98d89a7bc9 705 Gene3D G3DSA:3.30.1490.20 506 581 1.2E-57 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MIM_c24820 bd5fc0200a655e4cae809a98d89a7bc9 705 Gene3D G3DSA:3.30.470.20 487 698 1.2E-57 T 12-10-2018 MIM_c24820 bd5fc0200a655e4cae809a98d89a7bc9 705 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 163 299 2.4E-37 T 12-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain MIM_c24820 bd5fc0200a655e4cae809a98d89a7bc9 705 SUPERFAMILY SSF51735 6 144 2.49E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c24820 bd5fc0200a655e4cae809a98d89a7bc9 705 SUPERFAMILY SSF56059 487 698 1.87E-31 T 12-10-2018 MIM_c24820 bd5fc0200a655e4cae809a98d89a7bc9 705 Gene3D G3DSA:3.40.50.720 8 136 5.6E-38 T 12-10-2018 MIM_c24820 bd5fc0200a655e4cae809a98d89a7bc9 705 SUPERFAMILY SSF52210 309 459 1.83E-22 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c24820 bd5fc0200a655e4cae809a98d89a7bc9 705 SUPERFAMILY SSF52210 149 301 1.7E-31 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c31220 7e0b336094f2fe6bd9b2cd97527290ca 561 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 125 135 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MIM_c31220 7e0b336094f2fe6bd9b2cd97527290ca 561 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 7 559 43.458 T 12-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MIM_c31220 7e0b336094f2fe6bd9b2cd97527290ca 561 SUPERFAMILY SSF143975 5 380 8.5E-134 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MIM_c31220 7e0b336094f2fe6bd9b2cd97527290ca 561 Pfam PF00920 Dehydratase family 37 556 2.9E-201 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MIM_c31220 7e0b336094f2fe6bd9b2cd97527290ca 561 SUPERFAMILY SSF52016 382 559 7.85E-55 T 12-10-2018 MIM_c31220 7e0b336094f2fe6bd9b2cd97527290ca 561 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 467 478 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MIM_c31220 7e0b336094f2fe6bd9b2cd97527290ca 561 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 20 559 2.9E-223 T 12-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MIM_c31220 7e0b336094f2fe6bd9b2cd97527290ca 561 Gene3D G3DSA:3.50.30.80 381 530 5.5E-50 T 12-10-2018 MIM_c17470 a2c0be9899652ffd96fcd10fec8b15e2 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.7E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c17470 a2c0be9899652ffd96fcd10fec8b15e2 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.7E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c17470 a2c0be9899652ffd96fcd10fec8b15e2 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.7E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c17470 a2c0be9899652ffd96fcd10fec8b15e2 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.7E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c17470 a2c0be9899652ffd96fcd10fec8b15e2 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.7E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c17470 a2c0be9899652ffd96fcd10fec8b15e2 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 2.7E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c17470 a2c0be9899652ffd96fcd10fec8b15e2 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 257 2.1E-47 T 12-10-2018 MIM_c17470 a2c0be9899652ffd96fcd10fec8b15e2 261 Gene3D G3DSA:3.40.50.720 3 260 9.0E-67 T 12-10-2018 MIM_c17470 a2c0be9899652ffd96fcd10fec8b15e2 261 SUPERFAMILY SSF51735 7 259 1.21E-67 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c26130 f8692a158159ccfddd63fb5159bcf156 108 PIRSF PIRSF004555 2 108 2.0E-37 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MIM_c26130 f8692a158159ccfddd63fb5159bcf156 108 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 4 97 22.049 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MIM_c26130 f8692a158159ccfddd63fb5159bcf156 108 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 3 104 4.7E-32 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MIM_c26130 f8692a158159ccfddd63fb5159bcf156 108 SUPERFAMILY SSF82607 10 102 1.7E-34 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily MIM_c26130 f8692a158159ccfddd63fb5159bcf156 108 Pfam PF02575 YbaB/EbfC DNA-binding family 10 98 2.9E-34 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MIM_c26130 f8692a158159ccfddd63fb5159bcf156 108 Gene3D G3DSA:3.30.1310.10 1 108 1.3E-43 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily MIM_c28410 286294bfd55b359a9ca41cb9ac69df8e 468 Pfam PF02913 FAD linked oxidases, C-terminal domain 219 467 6.3E-54 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 MIM_c28410 286294bfd55b359a9ca41cb9ac69df8e 468 Gene3D G3DSA:3.30.43.10 1 93 2.4E-26 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 MIM_c28410 286294bfd55b359a9ca41cb9ac69df8e 468 Pfam PF01565 FAD binding domain 40 177 2.4E-35 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MIM_c28410 286294bfd55b359a9ca41cb9ac69df8e 468 SUPERFAMILY SSF56176 1 214 1.11E-70 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MIM_c28410 286294bfd55b359a9ca41cb9ac69df8e 468 Gene3D G3DSA:3.30.70.2190 216 340 6.8E-32 T 12-10-2018 MIM_c28410 286294bfd55b359a9ca41cb9ac69df8e 468 Gene3D G3DSA:1.10.45.10 428 468 2.4E-17 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 MIM_c28410 286294bfd55b359a9ca41cb9ac69df8e 468 SUPERFAMILY SSF55103 220 468 3.6E-56 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MIM_c28410 286294bfd55b359a9ca41cb9ac69df8e 468 Gene3D G3DSA:3.30.465.10 95 215 2.1E-41 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MIM_c28410 286294bfd55b359a9ca41cb9ac69df8e 468 Gene3D G3DSA:3.30.70.2740 341 427 2.4E-27 T 12-10-2018 MIM_c07500 d28964b1850d4b6f4fdc691cff82b27f 513 Gene3D G3DSA:3.40.50.300 94 382 1.3E-131 T 12-10-2018 MIM_c07500 d28964b1850d4b6f4fdc691cff82b27f 513 Gene3D G3DSA:2.40.30.20 1 93 2.6E-34 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MIM_c07500 d28964b1850d4b6f4fdc691cff82b27f 513 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 25 92 8.3E-17 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MIM_c07500 d28964b1850d4b6f4fdc691cff82b27f 513 SUPERFAMILY SSF50615 10 94 1.71E-28 T 12-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MIM_c07500 d28964b1850d4b6f4fdc691cff82b27f 513 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 505 2.4E-46 T 12-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07500 d28964b1850d4b6f4fdc691cff82b27f 513 Gene3D G3DSA:1.20.150.20 383 511 3.2E-47 T 12-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07500 d28964b1850d4b6f4fdc691cff82b27f 513 SUPERFAMILY SSF52540 96 381 5.32E-95 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c07500 d28964b1850d4b6f4fdc691cff82b27f 513 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 509 8.8E-249 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07500 d28964b1850d4b6f4fdc691cff82b27f 513 SUPERFAMILY SSF47917 383 509 1.83E-46 T 12-10-2018 MIM_c07500 d28964b1850d4b6f4fdc691cff82b27f 513 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MIM_c07500 d28964b1850d4b6f4fdc691cff82b27f 513 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 375 7.6E-74 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MIM_c07500 d28964b1850d4b6f4fdc691cff82b27f 513 PIRSF PIRSF039088 1 512 2.0E-237 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07500 d28964b1850d4b6f4fdc691cff82b27f 513 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 512 50.495 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c19110 56862d68c3444f437029055c87b7a2e7 412 Pfam PF02653 Branched-chain amino acid transport system / permease component 109 393 3.0E-50 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c19110 56862d68c3444f437029055c87b7a2e7 412 Pfam PF11862 Domain of unknown function (DUF3382) 3 99 2.0E-22 T 12-10-2018 IPR021807 High-affinity branched-chain amino acid transport system permease, LivHM, N-terminal MIM_c23300 41f90f15c768a60b3c04d48ab91a4599 499 Gene3D G3DSA:3.40.50.300 199 370 6.3E-21 T 12-10-2018 MIM_c23300 41f90f15c768a60b3c04d48ab91a4599 499 SUPERFAMILY SSF52540 11 372 4.12E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c23300 41f90f15c768a60b3c04d48ab91a4599 499 Pfam PF05872 Bacterial protein of unknown function (DUF853) 5 499 5.8E-232 T 12-10-2018 IPR033186 Helicase HerA-like C-terminal MIM_c23300 41f90f15c768a60b3c04d48ab91a4599 499 Gene3D G3DSA:3.40.50.300 6 89 1.4E-9 T 12-10-2018 MIM_c37570 2862e6c15a60d05bfef08bf0aac62ebc 243 SUPERFAMILY SSF46785 9 87 3.99E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c37570 2862e6c15a60d05bfef08bf0aac62ebc 243 Gene3D G3DSA:3.40.1410.10 84 241 7.8E-39 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MIM_c37570 2862e6c15a60d05bfef08bf0aac62ebc 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 3.4E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c37570 2862e6c15a60d05bfef08bf0aac62ebc 243 SUPERFAMILY SSF64288 66 240 3.93E-33 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MIM_c37570 2862e6c15a60d05bfef08bf0aac62ebc 243 SMART SM00866 96 238 2.1E-25 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MIM_c37570 2862e6c15a60d05bfef08bf0aac62ebc 243 Gene3D G3DSA:1.10.10.10 10 77 1.1E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c37570 2862e6c15a60d05bfef08bf0aac62ebc 243 Pfam PF07702 UTRA domain 101 237 1.0E-27 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MIM_c37570 2862e6c15a60d05bfef08bf0aac62ebc 243 SMART SM00345 17 76 3.2E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c07230 90d7b8dd0b0f38d03f1cb9818c824e1d 756 SMART SM00387 630 751 4.0E-29 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c07230 90d7b8dd0b0f38d03f1cb9818c824e1d 756 PRINTS PR00344 Bacterial sensor protein C-terminal signature 682 696 2.1E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c07230 90d7b8dd0b0f38d03f1cb9818c824e1d 756 PRINTS PR00344 Bacterial sensor protein C-terminal signature 711 729 2.1E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c07230 90d7b8dd0b0f38d03f1cb9818c824e1d 756 PRINTS PR00344 Bacterial sensor protein C-terminal signature 700 710 2.1E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c07230 90d7b8dd0b0f38d03f1cb9818c824e1d 756 Pfam PF00672 HAMP domain 314 362 1.2E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MIM_c07230 90d7b8dd0b0f38d03f1cb9818c824e1d 756 Gene3D G3DSA:1.10.287.130 499 578 7.2E-11 T 12-10-2018 MIM_c07230 90d7b8dd0b0f38d03f1cb9818c824e1d 756 Pfam PF00512 His Kinase A (phospho-acceptor) domain 510 577 8.1E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MIM_c07230 90d7b8dd0b0f38d03f1cb9818c824e1d 756 SMART SM00304 314 366 3.9E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MIM_c07230 90d7b8dd0b0f38d03f1cb9818c824e1d 756 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 631 747 1.7E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c07230 90d7b8dd0b0f38d03f1cb9818c824e1d 756 SUPERFAMILY SSF47384 506 579 1.96E-10 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MIM_c07230 90d7b8dd0b0f38d03f1cb9818c824e1d 756 Gene3D G3DSA:3.30.450.20 370 498 1.3E-13 T 12-10-2018 MIM_c07230 90d7b8dd0b0f38d03f1cb9818c824e1d 756 Gene3D G3DSA:3.30.565.10 581 752 8.2E-35 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c07230 90d7b8dd0b0f38d03f1cb9818c824e1d 756 SMART SM00388 509 581 2.9E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MIM_c07230 90d7b8dd0b0f38d03f1cb9818c824e1d 756 PIRSF PIRSF037532 1 755 1.5E-217 T 12-10-2018 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator MIM_c07230 90d7b8dd0b0f38d03f1cb9818c824e1d 756 SUPERFAMILY SSF55785 373 499 1.45E-8 T 12-10-2018 IPR035965 PAS domain superfamily MIM_c07230 90d7b8dd0b0f38d03f1cb9818c824e1d 756 Pfam PF13188 PAS domain 380 439 3.1E-4 T 12-10-2018 IPR000014 PAS domain MIM_c07230 90d7b8dd0b0f38d03f1cb9818c824e1d 756 SUPERFAMILY SSF55874 580 747 4.98E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c07230 90d7b8dd0b0f38d03f1cb9818c824e1d 756 Gene3D G3DSA:1.20.1480.50 279 369 9.0E-10 T 12-10-2018 MIM_c07230 90d7b8dd0b0f38d03f1cb9818c824e1d 756 SUPERFAMILY SSF158472 314 363 1.7E-6 T 12-10-2018 MIM_c11620 97e9792795ad11d92ab533f1ee5fde48 252 Gene3D G3DSA:2.40.50.100 119 249 2.7E-27 T 12-10-2018 MIM_c11620 97e9792795ad11d92ab533f1ee5fde48 252 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 18 81 9.7E-13 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c11620 97e9792795ad11d92ab533f1ee5fde48 252 Gene3D G3DSA:2.40.50.100 178 242 2.7E-27 T 12-10-2018 MIM_c11620 97e9792795ad11d92ab533f1ee5fde48 252 SUPERFAMILY SSF50331 119 186 7.94E-14 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MIM_c11620 97e9792795ad11d92ab533f1ee5fde48 252 SUPERFAMILY SSF46785 8 99 6.35E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c11620 97e9792795ad11d92ab533f1ee5fde48 252 SUPERFAMILY SSF50331 192 251 1.66E-5 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MIM_c11620 97e9792795ad11d92ab533f1ee5fde48 252 Pfam PF03459 TOBE domain 120 182 2.6E-9 T 12-10-2018 IPR005116 Transport-associated OB, type 1 MIM_c11620 97e9792795ad11d92ab533f1ee5fde48 252 PIRSF PIRSF005763 2 252 3.3E-56 T 12-10-2018 IPR016462 Molybdate-dependent transcriptional regulator ModE GO:0006355|GO:0015689|GO:0030151 MIM_c11620 97e9792795ad11d92ab533f1ee5fde48 252 Gene3D G3DSA:1.10.10.10 1 114 1.3E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c12070 ca677a5b86503e003ac4aaff0f7da944 549 Pfam PF13193 AMP-binding enzyme C-terminal domain 465 542 1.7E-23 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MIM_c12070 ca677a5b86503e003ac4aaff0f7da944 549 Gene3D G3DSA:3.40.50.12780 13 451 1.4E-112 T 12-10-2018 MIM_c12070 ca677a5b86503e003ac4aaff0f7da944 549 SUPERFAMILY SSF56801 21 548 2.88E-149 T 12-10-2018 MIM_c12070 ca677a5b86503e003ac4aaff0f7da944 549 Pfam PF00501 AMP-binding enzyme 32 455 6.7E-104 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MIM_c12070 ca677a5b86503e003ac4aaff0f7da944 549 ProSitePatterns PS00455 Putative AMP-binding domain signature. 206 217 - T 12-10-2018 IPR020845 AMP-binding, conserved site MIM_c12070 ca677a5b86503e003ac4aaff0f7da944 549 Gene3D G3DSA:3.30.300.310 452 549 8.9E-29 T 12-10-2018 MIM_c10220 9b4a93cc63f4f46c735d461e8e267a93 78 Gene3D G3DSA:1.10.10.60 1 77 6.8E-20 T 12-10-2018 MIM_c10220 9b4a93cc63f4f46c735d461e8e267a93 78 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 58 78 3.3E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MIM_c10220 9b4a93cc63f4f46c735d461e8e267a93 78 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 41 58 3.3E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MIM_c10220 9b4a93cc63f4f46c735d461e8e267a93 78 PIRSF PIRSF002097 1 78 3.4E-26 T 12-10-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 MIM_c10220 9b4a93cc63f4f46c735d461e8e267a93 78 SUPERFAMILY SSF46689 8 76 2.01E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c10220 9b4a93cc63f4f46c735d461e8e267a93 78 Pfam PF02954 Bacterial regulatory protein, Fis family 38 72 6.5E-13 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MIM_c21650 53e2184c658a54fddc6078c9ba381a6d 1353 Pfam PF02769 AIR synthase related protein, C-terminal domain 454 606 9.6E-23 T 12-10-2018 IPR010918 PurM-like, C-terminal domain MIM_c21650 53e2184c658a54fddc6078c9ba381a6d 1353 Pfam PF02769 AIR synthase related protein, C-terminal domain 882 1012 1.0E-13 T 12-10-2018 IPR010918 PurM-like, C-terminal domain MIM_c21650 53e2184c658a54fddc6078c9ba381a6d 1353 SUPERFAMILY SSF55326 235 441 1.43E-55 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MIM_c21650 53e2184c658a54fddc6078c9ba381a6d 1353 Gene3D G3DSA:3.30.1330.10 647 840 1.2E-18 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MIM_c21650 53e2184c658a54fddc6078c9ba381a6d 1353 Gene3D G3DSA:3.40.50.880 1037 1353 7.5E-118 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c21650 53e2184c658a54fddc6078c9ba381a6d 1353 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 13 1351 0.0 T 12-10-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MIM_c21650 53e2184c658a54fddc6078c9ba381a6d 1353 Gene3D G3DSA:3.90.650.10 436 614 1.9E-51 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MIM_c21650 53e2184c658a54fddc6078c9ba381a6d 1353 Gene3D G3DSA:3.30.1330.10 228 435 7.1E-41 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MIM_c21650 53e2184c658a54fddc6078c9ba381a6d 1353 Gene3D G3DSA:3.90.650.10 841 1036 2.4E-29 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MIM_c21650 53e2184c658a54fddc6078c9ba381a6d 1353 SUPERFAMILY SSF56042 453 687 1.18E-44 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MIM_c21650 53e2184c658a54fddc6078c9ba381a6d 1353 SUPERFAMILY SSF82697 9 160 1.67E-39 T 12-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MIM_c21650 53e2184c658a54fddc6078c9ba381a6d 1353 SUPERFAMILY SSF55326 654 847 2.88E-61 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MIM_c21650 53e2184c658a54fddc6078c9ba381a6d 1353 SUPERFAMILY SSF56042 855 1088 5.53E-47 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MIM_c21650 53e2184c658a54fddc6078c9ba381a6d 1353 SUPERFAMILY SSF52317 1092 1350 3.85E-85 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c21650 53e2184c658a54fddc6078c9ba381a6d 1353 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1095 1349 2.3E-95 T 12-10-2018 MIM_c21650 53e2184c658a54fddc6078c9ba381a6d 1353 SMART SM01211 1095 1352 1.7E-139 T 12-10-2018 MIM_c21650 53e2184c658a54fddc6078c9ba381a6d 1353 SUPERFAMILY SSF109736 169 234 3.53E-20 T 12-10-2018 MIM_c21650 53e2184c658a54fddc6078c9ba381a6d 1353 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 8 1353 20.126 T 12-10-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MIM_c21650 53e2184c658a54fddc6078c9ba381a6d 1353 Gene3D G3DSA:1.10.8.750 168 227 6.6E-24 T 12-10-2018 MIM_c34040 4061d86f67a8f6d7fc9bdc041a35959e 538 SUPERFAMILY SSF46689 422 538 2.96E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c34040 4061d86f67a8f6d7fc9bdc041a35959e 538 SMART SM00065 37 188 9.6E-10 T 12-10-2018 IPR003018 GAF domain GO:0005515 MIM_c34040 4061d86f67a8f6d7fc9bdc041a35959e 538 Gene3D G3DSA:3.40.50.300 199 381 2.8E-67 T 12-10-2018 MIM_c34040 4061d86f67a8f6d7fc9bdc041a35959e 538 Pfam PF02954 Bacterial regulatory protein, Fis family 504 535 2.7E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MIM_c34040 4061d86f67a8f6d7fc9bdc041a35959e 538 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 422 431 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site MIM_c34040 4061d86f67a8f6d7fc9bdc041a35959e 538 Gene3D G3DSA:1.10.10.60 494 538 2.4E-7 T 12-10-2018 MIM_c34040 4061d86f67a8f6d7fc9bdc041a35959e 538 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 234 247 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MIM_c34040 4061d86f67a8f6d7fc9bdc041a35959e 538 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 296 311 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MIM_c34040 4061d86f67a8f6d7fc9bdc041a35959e 538 Pfam PF01590 GAF domain 39 175 3.3E-12 T 12-10-2018 IPR003018 GAF domain GO:0005515 MIM_c34040 4061d86f67a8f6d7fc9bdc041a35959e 538 SUPERFAMILY SSF52540 209 452 6.84E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c34040 4061d86f67a8f6d7fc9bdc041a35959e 538 SUPERFAMILY SSF55781 21 179 7.41E-18 T 12-10-2018 MIM_c34040 4061d86f67a8f6d7fc9bdc041a35959e 538 SMART SM00382 230 373 1.3E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c34040 4061d86f67a8f6d7fc9bdc041a35959e 538 Gene3D G3DSA:3.30.450.40 17 190 2.8E-34 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c34040 4061d86f67a8f6d7fc9bdc041a35959e 538 Pfam PF00158 Sigma-54 interaction domain 210 377 6.3E-72 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MIM_c34040 4061d86f67a8f6d7fc9bdc041a35959e 538 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 502 519 1.2E-9 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MIM_c34040 4061d86f67a8f6d7fc9bdc041a35959e 538 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 519 538 1.2E-9 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MIM_c34040 4061d86f67a8f6d7fc9bdc041a35959e 538 Gene3D G3DSA:1.10.8.60 383 453 1.8E-23 T 12-10-2018 MIM_c39970 47ec7c846baba527d7206753bf2540cb 522 Gene3D G3DSA:3.50.50.60 438 521 1.8E-12 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c39970 47ec7c846baba527d7206753bf2540cb 522 Gene3D G3DSA:3.50.50.60 177 345 4.9E-8 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c39970 47ec7c846baba527d7206753bf2540cb 522 Gene3D G3DSA:3.50.50.60 9 169 4.6E-18 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c39970 47ec7c846baba527d7206753bf2540cb 522 Pfam PF05199 GMC oxidoreductase 390 508 4.1E-22 T 12-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 MIM_c39970 47ec7c846baba527d7206753bf2540cb 522 SUPERFAMILY SSF54373 291 458 1.02E-14 T 12-10-2018 MIM_c39970 47ec7c846baba527d7206753bf2540cb 522 Pfam PF00732 GMC oxidoreductase 13 282 1.3E-20 T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c39970 47ec7c846baba527d7206753bf2540cb 522 SUPERFAMILY SSF51905 12 518 1.21E-59 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c35650 c1cefa7dda73c7bdba07956231b6ebc3 254 SUPERFAMILY SSF161098 48 230 2.49E-31 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c35650 c1cefa7dda73c7bdba07956231b6ebc3 254 Gene3D G3DSA:1.10.3720.10 48 239 3.1E-24 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c35650 c1cefa7dda73c7bdba07956231b6ebc3 254 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 238 1.1E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c15030 fa3af0bd46a3384436a6e557b6755bb7 453 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 448 1.4E-187 T 12-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 MIM_c15030 fa3af0bd46a3384436a6e557b6755bb7 453 Gene3D G3DSA:3.40.50.300 65 279 1.3E-41 T 12-10-2018 MIM_c15030 fa3af0bd46a3384436a6e557b6755bb7 453 Gene3D G3DSA:3.30.230.10 331 453 5.2E-14 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MIM_c15030 fa3af0bd46a3384436a6e557b6755bb7 453 SUPERFAMILY SSF54211 253 452 8.72E-38 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MIM_c15030 fa3af0bd46a3384436a6e557b6755bb7 453 SUPERFAMILY SSF52540 67 289 2.9E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c15030 fa3af0bd46a3384436a6e557b6755bb7 453 Hamap MF_01498 DNA repair protein RadA [radA]. 21 453 43.268 T 12-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 MIM_c15030 fa3af0bd46a3384436a6e557b6755bb7 453 PRINTS PR01874 DNA repair protein radA signature 122 139 4.0E-94 T 12-10-2018 MIM_c15030 fa3af0bd46a3384436a6e557b6755bb7 453 PRINTS PR01874 DNA repair protein radA signature 10 34 4.0E-94 T 12-10-2018 MIM_c15030 fa3af0bd46a3384436a6e557b6755bb7 453 PRINTS PR01874 DNA repair protein radA signature 320 343 4.0E-94 T 12-10-2018 MIM_c15030 fa3af0bd46a3384436a6e557b6755bb7 453 PRINTS PR01874 DNA repair protein radA signature 211 239 4.0E-94 T 12-10-2018 MIM_c15030 fa3af0bd46a3384436a6e557b6755bb7 453 PRINTS PR01874 DNA repair protein radA signature 172 196 4.0E-94 T 12-10-2018 MIM_c15030 fa3af0bd46a3384436a6e557b6755bb7 453 PRINTS PR01874 DNA repair protein radA signature 246 272 4.0E-94 T 12-10-2018 MIM_c15030 fa3af0bd46a3384436a6e557b6755bb7 453 PRINTS PR01874 DNA repair protein radA signature 81 109 4.0E-94 T 12-10-2018 MIM_c15030 fa3af0bd46a3384436a6e557b6755bb7 453 SMART SM00382 89 242 8.7E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c15030 fa3af0bd46a3384436a6e557b6755bb7 453 Pfam PF13481 AAA domain 84 220 1.7E-16 T 12-10-2018 MIM_c15030 fa3af0bd46a3384436a6e557b6755bb7 453 Pfam PF13541 Subunit ChlI of Mg-chelatase 348 428 1.7E-6 T 12-10-2018 MIM_c23160 54efb3594a312424a5045854c921ea3c 458 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 16 454 2.3E-124 T 12-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MIM_c23160 54efb3594a312424a5045854c921ea3c 458 ProSitePatterns PS00163 Fumarate lyases signature. 297 306 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MIM_c23160 54efb3594a312424a5045854c921ea3c 458 Pfam PF08328 Adenylosuccinate lyase C-terminal 334 448 1.0E-49 T 12-10-2018 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 MIM_c23160 54efb3594a312424a5045854c921ea3c 458 Pfam PF00206 Lyase 18 315 3.0E-58 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal MIM_c23160 54efb3594a312424a5045854c921ea3c 458 Gene3D G3DSA:1.10.40.30 385 448 1.2E-145 T 12-10-2018 MIM_c23160 54efb3594a312424a5045854c921ea3c 458 PRINTS PR00149 Fumarate lyase superfamily signature 254 281 6.5E-17 T 12-10-2018 IPR000362 Fumarate lyase family MIM_c23160 54efb3594a312424a5045854c921ea3c 458 PRINTS PR00149 Fumarate lyase superfamily signature 166 184 6.5E-17 T 12-10-2018 IPR000362 Fumarate lyase family MIM_c23160 54efb3594a312424a5045854c921ea3c 458 PRINTS PR00149 Fumarate lyase superfamily signature 120 138 6.5E-17 T 12-10-2018 IPR000362 Fumarate lyase family MIM_c23160 54efb3594a312424a5045854c921ea3c 458 PRINTS PR00149 Fumarate lyase superfamily signature 297 313 6.5E-17 T 12-10-2018 IPR000362 Fumarate lyase family MIM_c23160 54efb3594a312424a5045854c921ea3c 458 Gene3D G3DSA:1.10.275.10 2 120 2.4E-41 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal MIM_c23160 54efb3594a312424a5045854c921ea3c 458 Gene3D G3DSA:1.20.200.10 121 449 1.2E-145 T 12-10-2018 MIM_c23160 54efb3594a312424a5045854c921ea3c 458 SUPERFAMILY SSF48557 7 450 6.6E-100 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 MIM_c11160 bc59f62ad36464bb0467673576c75805 319 Gene3D G3DSA:3.40.630.10 15 315 3.9E-53 T 12-10-2018 MIM_c11160 bc59f62ad36464bb0467673576c75805 319 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 33 199 1.7E-15 T 12-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 MIM_c11160 bc59f62ad36464bb0467673576c75805 319 SUPERFAMILY SSF53187 4 311 7.85E-52 T 12-10-2018 MIM_c30960 23bcb2c94f97ebe9cf9d4bc661d87e7d 367 Gene3D G3DSA:2.40.37.10 6 367 1.4E-146 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MIM_c30960 23bcb2c94f97ebe9cf9d4bc661d87e7d 367 TIGRFAM TIGR01047 nspC: carboxynorspermidine decarboxylase 6 364 5.5E-124 T 12-10-2018 IPR005730 Carboxynorspermidine decarboxylase GO:0016831|GO:0045312 KEGG: 00330+4.1.1.96|MetaCyc: PWY-6562 MIM_c30960 23bcb2c94f97ebe9cf9d4bc661d87e7d 367 SUPERFAMILY SSF50621 208 356 2.51E-32 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MIM_c30960 23bcb2c94f97ebe9cf9d4bc661d87e7d 367 PIRSF PIRSF038941 1 367 1.2E-136 T 12-10-2018 IPR005730 Carboxynorspermidine decarboxylase GO:0016831|GO:0045312 KEGG: 00330+4.1.1.96|MetaCyc: PWY-6562 MIM_c30960 23bcb2c94f97ebe9cf9d4bc661d87e7d 367 Gene3D G3DSA:3.20.20.10 13 239 1.4E-146 T 12-10-2018 IPR029066 PLP-binding barrel MIM_c30960 23bcb2c94f97ebe9cf9d4bc661d87e7d 367 SUPERFAMILY SSF51419 12 240 8.34E-41 T 12-10-2018 IPR029066 PLP-binding barrel MIM_c30960 23bcb2c94f97ebe9cf9d4bc661d87e7d 367 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 194 324 3.4E-11 T 12-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 MIM_c14580 54cfa3f88aad31066ac7a58a6c1d9227 428 Hamap MF_00318 Enolase [eno]. 2 412 44.641 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MIM_c14580 54cfa3f88aad31066ac7a58a6c1d9227 428 SUPERFAMILY SSF54826 4 136 2.05E-56 T 12-10-2018 MIM_c14580 54cfa3f88aad31066ac7a58a6c1d9227 428 ProSitePatterns PS00164 Enolase signature. 335 348 - T 12-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c14580 54cfa3f88aad31066ac7a58a6c1d9227 428 SMART SM01193 4 134 5.5E-95 T 12-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MIM_c14580 54cfa3f88aad31066ac7a58a6c1d9227 428 Gene3D G3DSA:3.20.20.120 128 428 2.0E-131 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MIM_c14580 54cfa3f88aad31066ac7a58a6c1d9227 428 Pfam PF03952 Enolase, N-terminal domain 4 133 3.8E-59 T 12-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MIM_c14580 54cfa3f88aad31066ac7a58a6c1d9227 428 PIRSF PIRSF001400 1 426 1.9E-189 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MIM_c14580 54cfa3f88aad31066ac7a58a6c1d9227 428 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 424 1.3E-130 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MIM_c14580 54cfa3f88aad31066ac7a58a6c1d9227 428 SMART SM01192 139 426 1.2E-217 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MIM_c14580 54cfa3f88aad31066ac7a58a6c1d9227 428 Gene3D G3DSA:3.30.390.10 1 127 3.6E-57 T 12-10-2018 IPR029017 Enolase-like, N-terminal MIM_c14580 54cfa3f88aad31066ac7a58a6c1d9227 428 PRINTS PR00148 Enolase signature 335 349 3.9E-46 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MIM_c14580 54cfa3f88aad31066ac7a58a6c1d9227 428 PRINTS PR00148 Enolase signature 161 174 3.9E-46 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MIM_c14580 54cfa3f88aad31066ac7a58a6c1d9227 428 PRINTS PR00148 Enolase signature 312 323 3.9E-46 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MIM_c14580 54cfa3f88aad31066ac7a58a6c1d9227 428 PRINTS PR00148 Enolase signature 107 123 3.9E-46 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MIM_c14580 54cfa3f88aad31066ac7a58a6c1d9227 428 PRINTS PR00148 Enolase signature 37 51 3.9E-46 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MIM_c14580 54cfa3f88aad31066ac7a58a6c1d9227 428 PRINTS PR00148 Enolase signature 364 381 3.9E-46 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MIM_c14580 54cfa3f88aad31066ac7a58a6c1d9227 428 SUPERFAMILY SSF51604 139 427 1.56E-127 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MIM_c14580 54cfa3f88aad31066ac7a58a6c1d9227 428 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 426 8.1E-207 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MIM_c14180 f27a47245c7adee2a6bf76d4b8cb2b19 357 Gene3D G3DSA:2.40.50.940 222 349 4.3E-28 T 12-10-2018 MIM_c14180 f27a47245c7adee2a6bf76d4b8cb2b19 357 SUPERFAMILY SSF52540 4 242 8.52E-85 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c14180 f27a47245c7adee2a6bf76d4b8cb2b19 357 SUPERFAMILY SSF50331 236 356 5.35E-25 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MIM_c14180 f27a47245c7adee2a6bf76d4b8cb2b19 357 SMART SM00382 28 211 1.5E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c14180 f27a47245c7adee2a6bf76d4b8cb2b19 357 Gene3D G3DSA:2.40.50.140 287 340 4.3E-28 T 12-10-2018 MIM_c14180 f27a47245c7adee2a6bf76d4b8cb2b19 357 Pfam PF08402 TOBE domain 281 348 5.9E-7 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 MIM_c14180 f27a47245c7adee2a6bf76d4b8cb2b19 357 Gene3D G3DSA:3.40.50.300 2 221 6.3E-66 T 12-10-2018 MIM_c14180 f27a47245c7adee2a6bf76d4b8cb2b19 357 Pfam PF00005 ABC transporter 19 161 9.3E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c14180 f27a47245c7adee2a6bf76d4b8cb2b19 357 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c16210 c76e350821664854a83c56f6103b5db9 296 Pfam PF04909 Amidohydrolase 23 286 9.6E-38 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MIM_c16210 c76e350821664854a83c56f6103b5db9 296 Gene3D G3DSA:3.20.20.140 3 294 2.1E-74 T 12-10-2018 MIM_c16210 c76e350821664854a83c56f6103b5db9 296 SUPERFAMILY SSF51556 19 286 1.32E-67 T 12-10-2018 IPR032466 Metal-dependent hydrolase MIM_c18250 27b7b0b5cba5de12fd6cb89a4753b2b3 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 7.8E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c18250 27b7b0b5cba5de12fd6cb89a4753b2b3 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 7.8E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c18250 27b7b0b5cba5de12fd6cb89a4753b2b3 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 7.8E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c18250 27b7b0b5cba5de12fd6cb89a4753b2b3 306 SUPERFAMILY SSF46785 2 112 1.11E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c18250 27b7b0b5cba5de12fd6cb89a4753b2b3 306 Pfam PF03466 LysR substrate binding domain 89 293 5.4E-39 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c18250 27b7b0b5cba5de12fd6cb89a4753b2b3 306 Gene3D G3DSA:1.10.10.10 1 91 1.7E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c18250 27b7b0b5cba5de12fd6cb89a4753b2b3 306 SUPERFAMILY SSF53850 89 294 1.72E-38 T 12-10-2018 MIM_c18250 27b7b0b5cba5de12fd6cb89a4753b2b3 306 Gene3D G3DSA:3.40.190.10 92 292 2.2E-73 T 12-10-2018 MIM_c18250 27b7b0b5cba5de12fd6cb89a4753b2b3 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 4.1E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c18250 27b7b0b5cba5de12fd6cb89a4753b2b3 306 Gene3D G3DSA:3.40.190.10 163 269 2.2E-73 T 12-10-2018 MIM_c23220 823f326851b518c7d283fc7d58880fdc 485 Gene3D G3DSA:3.30.2290.10 12 244 1.7E-18 T 12-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal MIM_c23220 823f326851b518c7d283fc7d58880fdc 485 SUPERFAMILY SSF111283 25 484 1.57E-132 T 12-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 MIM_c23220 823f326851b518c7d283fc7d58880fdc 485 PIRSF PIRSF004919 23 485 2.2E-136 T 12-10-2018 IPR025502 TldD MIM_c23220 823f326851b518c7d283fc7d58880fdc 485 Pfam PF01523 Putative modulator of DNA gyrase 43 336 2.5E-68 T 12-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 MIM_c37650 87be59b91f9a44060c812596dacc6e24 543 Pfam PF13403 Hint domain 203 339 6.3E-43 T 12-10-2018 IPR028992 Hedgehog/Intein (Hint) domain MIM_c37650 87be59b91f9a44060c812596dacc6e24 543 SUPERFAMILY SSF51294 202 327 1.07E-15 T 12-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MIM_c02240 59d863e1bd9d0d0802f67f16b0cf4f32 244 Gene3D G3DSA:3.40.50.720 1 244 2.9E-77 T 12-10-2018 MIM_c02240 59d863e1bd9d0d0802f67f16b0cf4f32 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 2.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c02240 59d863e1bd9d0d0802f67f16b0cf4f32 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c02240 59d863e1bd9d0d0802f67f16b0cf4f32 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 2.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c02240 59d863e1bd9d0d0802f67f16b0cf4f32 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c02240 59d863e1bd9d0d0802f67f16b0cf4f32 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 2.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c02240 59d863e1bd9d0d0802f67f16b0cf4f32 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c02240 59d863e1bd9d0d0802f67f16b0cf4f32 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 6.9E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c02240 59d863e1bd9d0d0802f67f16b0cf4f32 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 6.9E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c02240 59d863e1bd9d0d0802f67f16b0cf4f32 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 6.9E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c02240 59d863e1bd9d0d0802f67f16b0cf4f32 244 SUPERFAMILY SSF51735 3 243 2.77E-75 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c02240 59d863e1bd9d0d0802f67f16b0cf4f32 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c02240 59d863e1bd9d0d0802f67f16b0cf4f32 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 218 0.0012 T 12-10-2018 MIM_c02240 59d863e1bd9d0d0802f67f16b0cf4f32 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 243 1.1E-57 T 12-10-2018 MIM_c12490 38c1a0b8fed9ee5e3ec5f15e9a245769 327 Gene3D G3DSA:3.40.190.10 129 252 2.5E-116 T 12-10-2018 MIM_c12490 38c1a0b8fed9ee5e3ec5f15e9a245769 327 Gene3D G3DSA:3.40.190.150 32 317 2.5E-116 T 12-10-2018 MIM_c12490 38c1a0b8fed9ee5e3ec5f15e9a245769 327 SUPERFAMILY SSF53850 113 294 5.87E-13 T 12-10-2018 MIM_c12490 38c1a0b8fed9ee5e3ec5f15e9a245769 327 PIRSF PIRSF017082 1 327 8.1E-83 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c12490 38c1a0b8fed9ee5e3ec5f15e9a245769 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 321 3.1E-96 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c20480 ae6b6aec7656881f49e4f1a4ab3a8ac2 242 Pfam PF01872 RibD C-terminal domain 3 229 2.1E-14 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 MIM_c20480 ae6b6aec7656881f49e4f1a4ab3a8ac2 242 Gene3D G3DSA:3.40.430.10 1 236 1.5E-32 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MIM_c20480 ae6b6aec7656881f49e4f1a4ab3a8ac2 242 SUPERFAMILY SSF53597 1 234 5.89E-27 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MIM_c34090 829ff561a557e77b49a53625ecadac0f 452 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 80 353 9.1E-38 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MIM_c34090 829ff561a557e77b49a53625ecadac0f 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 219 237 6.3E-18 T 12-10-2018 MIM_c34090 829ff561a557e77b49a53625ecadac0f 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 80 99 6.3E-18 T 12-10-2018 MIM_c34090 829ff561a557e77b49a53625ecadac0f 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 331 353 6.3E-18 T 12-10-2018 MIM_c34090 829ff561a557e77b49a53625ecadac0f 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 175 193 6.3E-18 T 12-10-2018 MIM_c34090 829ff561a557e77b49a53625ecadac0f 452 Gene3D G3DSA:2.20.28.10 3 62 1.1E-24 T 12-10-2018 MIM_c34090 829ff561a557e77b49a53625ecadac0f 452 ProSitePatterns PS00202 Rubredoxin signature. 40 50 - T 12-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 MIM_c34090 829ff561a557e77b49a53625ecadac0f 452 Gene3D G3DSA:3.50.50.60 81 353 8.8E-64 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c34090 829ff561a557e77b49a53625ecadac0f 452 Pfam PF00301 Rubredoxin 11 56 3.3E-21 T 12-10-2018 IPR024935 Rubredoxin domain GO:0005506 MIM_c34090 829ff561a557e77b49a53625ecadac0f 452 Gene3D G3DSA:3.50.50.60 183 317 8.8E-64 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c34090 829ff561a557e77b49a53625ecadac0f 452 SUPERFAMILY SSF51905 79 380 4.35E-34 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c34090 829ff561a557e77b49a53625ecadac0f 452 SUPERFAMILY SSF57802 7 61 2.36E-20 T 12-10-2018 MIM_c34090 829ff561a557e77b49a53625ecadac0f 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 346 353 7.6E-13 T 12-10-2018 MIM_c34090 829ff561a557e77b49a53625ecadac0f 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 79 101 7.6E-13 T 12-10-2018 MIM_c34090 829ff561a557e77b49a53625ecadac0f 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 219 244 7.6E-13 T 12-10-2018 MIM_c34090 829ff561a557e77b49a53625ecadac0f 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 306 320 7.6E-13 T 12-10-2018 MIM_c34090 829ff561a557e77b49a53625ecadac0f 452 PRINTS PR00163 Rubredoxin signature 40 56 5.3E-8 T 12-10-2018 IPR024935 Rubredoxin domain GO:0005506 MIM_c34090 829ff561a557e77b49a53625ecadac0f 452 PRINTS PR00163 Rubredoxin signature 10 26 5.3E-8 T 12-10-2018 IPR024935 Rubredoxin domain GO:0005506 MIM_c00490 f1581d7814c645a871f8a29ce4dc4ae1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.1E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c00490 f1581d7814c645a871f8a29ce4dc4ae1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 1.1E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c00490 f1581d7814c645a871f8a29ce4dc4ae1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.1E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c00490 f1581d7814c645a871f8a29ce4dc4ae1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.1E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c00490 f1581d7814c645a871f8a29ce4dc4ae1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.1E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c00490 f1581d7814c645a871f8a29ce4dc4ae1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.1E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c00490 f1581d7814c645a871f8a29ce4dc4ae1 258 Gene3D G3DSA:3.40.50.720 1 257 3.4E-51 T 12-10-2018 MIM_c00490 f1581d7814c645a871f8a29ce4dc4ae1 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 257 1.4E-29 T 12-10-2018 MIM_c00490 f1581d7814c645a871f8a29ce4dc4ae1 258 SUPERFAMILY SSF51735 6 257 5.88E-51 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c33180 a5bb497a2573656b27708be170ab2839 205 Gene3D G3DSA:3.40.80.10 14 187 3.6E-54 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MIM_c33180 a5bb497a2573656b27708be170ab2839 205 SUPERFAMILY SSF55846 20 191 1.18E-60 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MIM_c33180 a5bb497a2573656b27708be170ab2839 205 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 37 175 2.8E-26 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MIM_c33180 a5bb497a2573656b27708be170ab2839 205 SMART SM00644 26 174 2.4E-48 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MIM_c12700 fd13f651d27ba00b81c85c1fb0c87079 694 SUPERFAMILY SSF52210 145 294 7.85E-40 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c12700 fd13f651d27ba00b81c85c1fb0c87079 694 Gene3D G3DSA:3.40.50.720 1 129 1.4E-34 T 12-10-2018 MIM_c12700 fd13f651d27ba00b81c85c1fb0c87079 694 Gene3D G3DSA:3.40.50.261 298 460 2.2E-27 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c12700 fd13f651d27ba00b81c85c1fb0c87079 694 Gene3D G3DSA:3.30.1490.20 495 570 8.0E-58 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MIM_c12700 fd13f651d27ba00b81c85c1fb0c87079 694 Pfam PF13380 CoA binding domain 11 133 1.5E-16 T 12-10-2018 IPR003781 CoA-binding GO:0048037 MIM_c12700 fd13f651d27ba00b81c85c1fb0c87079 694 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 156 292 5.2E-49 T 12-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain MIM_c12700 fd13f651d27ba00b81c85c1fb0c87079 694 SUPERFAMILY SSF51735 2 137 1.61E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c12700 fd13f651d27ba00b81c85c1fb0c87079 694 Pfam PF13549 ATP-grasp domain 475 688 6.5E-50 T 12-10-2018 MIM_c12700 fd13f651d27ba00b81c85c1fb0c87079 694 Gene3D G3DSA:3.30.470.20 476 687 8.0E-58 T 12-10-2018 MIM_c12700 fd13f651d27ba00b81c85c1fb0c87079 694 Gene3D G3DSA:3.40.50.261 133 295 7.4E-51 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c12700 fd13f651d27ba00b81c85c1fb0c87079 694 SUPERFAMILY SSF52210 300 452 1.44E-21 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c12700 fd13f651d27ba00b81c85c1fb0c87079 694 SMART SM00881 7 102 1.4E-27 T 12-10-2018 IPR003781 CoA-binding GO:0048037 MIM_c12700 fd13f651d27ba00b81c85c1fb0c87079 694 SUPERFAMILY SSF56059 477 691 1.94E-33 T 12-10-2018 MIM_c07040 3dda5f7c594b1056f8d2853e145f611e 354 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 329 1.4E-29 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c09070 98ad106dcebd67b7b4a8321dbc9fe59c 689 SUPERFAMILY SSF56601 252 620 2.18E-93 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MIM_c09070 98ad106dcebd67b7b4a8321dbc9fe59c 689 SUPERFAMILY SSF56519 55 251 4.45E-46 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 MIM_c09070 98ad106dcebd67b7b4a8321dbc9fe59c 689 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 18 620 9.7E-212 T 12-10-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0009002|GO:0009252|GO:0016020 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MIM_c09070 98ad106dcebd67b7b4a8321dbc9fe59c 689 Gene3D G3DSA:3.30.1390.30 83 158 2.5E-42 T 12-10-2018 MIM_c09070 98ad106dcebd67b7b4a8321dbc9fe59c 689 Hamap MF_02081 Peptidoglycan D,D-transpeptidase MrdA [mrdA]. 6 623 47.074 T 12-10-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0009002|GO:0009252|GO:0016020 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MIM_c09070 98ad106dcebd67b7b4a8321dbc9fe59c 689 Gene3D G3DSA:3.40.710.10 251 633 2.4E-95 T 12-10-2018 MIM_c09070 98ad106dcebd67b7b4a8321dbc9fe59c 689 Pfam PF03717 Penicillin-binding Protein dimerisation domain 62 237 3.8E-42 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MIM_c09070 98ad106dcebd67b7b4a8321dbc9fe59c 689 Pfam PF00905 Penicillin binding protein transpeptidase domain 277 615 7.6E-67 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MIM_c09070 98ad106dcebd67b7b4a8321dbc9fe59c 689 Gene3D G3DSA:3.90.1310.10 62 246 2.5E-42 T 12-10-2018 MIM_c31580 bdb43949e1e74c1a76437353fd49ae34 200 Pfam PF13577 SnoaL-like domain 12 145 2.0E-10 T 12-10-2018 IPR037401 SnoaL-like domain MIM_c31580 bdb43949e1e74c1a76437353fd49ae34 200 SUPERFAMILY SSF54427 6 154 7.69E-16 T 12-10-2018 IPR032710 NTF2-like domain superfamily MIM_c31580 bdb43949e1e74c1a76437353fd49ae34 200 Gene3D G3DSA:3.10.450.50 1 159 3.9E-29 T 12-10-2018 MIM_c04840 2986c06f41242aaffbe0e3c2020ae60d 222 Pfam PF01634 ATP phosphoribosyltransferase 56 212 3.5E-49 T 12-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 MIM_c04840 2986c06f41242aaffbe0e3c2020ae60d 222 Gene3D G3DSA:3.40.190.10 101 187 9.9E-70 T 12-10-2018 MIM_c04840 2986c06f41242aaffbe0e3c2020ae60d 222 SUPERFAMILY SSF53850 6 214 2.48E-64 T 12-10-2018 MIM_c04840 2986c06f41242aaffbe0e3c2020ae60d 222 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 6 219 55.607 T 12-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 MIM_c04840 2986c06f41242aaffbe0e3c2020ae60d 222 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 154 175 - T 12-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 MIM_c04840 2986c06f41242aaffbe0e3c2020ae60d 222 Gene3D G3DSA:3.40.190.10 8 206 9.9E-70 T 12-10-2018 MIM_c04840 2986c06f41242aaffbe0e3c2020ae60d 222 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 7 195 6.1E-60 T 12-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 MIM_c14970 034a6de2e763ac77f4be20f23e24f54c 592 Gene3D G3DSA:3.10.580.10 440 571 2.6E-17 T 12-10-2018 MIM_c14970 034a6de2e763ac77f4be20f23e24f54c 592 PRINTS PR00762 Chloride channel signature 365 381 3.7E-24 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MIM_c14970 034a6de2e763ac77f4be20f23e24f54c 592 PRINTS PR00762 Chloride channel signature 122 141 3.7E-24 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MIM_c14970 034a6de2e763ac77f4be20f23e24f54c 592 PRINTS PR00762 Chloride channel signature 173 192 3.7E-24 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MIM_c14970 034a6de2e763ac77f4be20f23e24f54c 592 PRINTS PR00762 Chloride channel signature 336 356 3.7E-24 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MIM_c14970 034a6de2e763ac77f4be20f23e24f54c 592 PRINTS PR00762 Chloride channel signature 383 402 3.7E-24 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MIM_c14970 034a6de2e763ac77f4be20f23e24f54c 592 Pfam PF00654 Voltage gated chloride channel 79 414 1.3E-68 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MIM_c14970 034a6de2e763ac77f4be20f23e24f54c 592 SUPERFAMILY SSF54631 446 573 1.16E-19 T 12-10-2018 MIM_c14970 034a6de2e763ac77f4be20f23e24f54c 592 SMART SM00116 455 505 3.0 T 12-10-2018 IPR000644 CBS domain MIM_c14970 034a6de2e763ac77f4be20f23e24f54c 592 SMART SM00116 522 571 2.3 T 12-10-2018 IPR000644 CBS domain MIM_c14970 034a6de2e763ac77f4be20f23e24f54c 592 Gene3D G3DSA:1.10.3080.10 6 436 1.0E-80 T 12-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 MIM_c14970 034a6de2e763ac77f4be20f23e24f54c 592 SUPERFAMILY SSF81340 8 437 3.01E-89 T 12-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 MIM_c14970 034a6de2e763ac77f4be20f23e24f54c 592 Pfam PF00571 CBS domain 526 569 0.0036 T 12-10-2018 IPR000644 CBS domain MIM_c14970 034a6de2e763ac77f4be20f23e24f54c 592 Pfam PF00571 CBS domain 448 496 3.0E-8 T 12-10-2018 IPR000644 CBS domain MIM_c23130 161fb43fe9ce72df0ae6f16b9ab2b9f0 187 SUPERFAMILY SSF117074 42 166 2.22E-8 T 12-10-2018 MIM_c05090 bc8edc6141a2e631d8aae343bc94f8c8 371 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 13 194 1.1E-52 T 12-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain MIM_c05090 bc8edc6141a2e631d8aae343bc94f8c8 371 SUPERFAMILY SSF52540 12 215 5.83E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c05090 bc8edc6141a2e631d8aae343bc94f8c8 371 SUPERFAMILY SSF90002 274 368 1.1E-23 T 12-10-2018 MIM_c05090 bc8edc6141a2e631d8aae343bc94f8c8 371 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 274 368 1.0E-19 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MIM_c05090 bc8edc6141a2e631d8aae343bc94f8c8 371 Gene3D G3DSA:3.30.1220.10 254 368 6.5E-33 T 12-10-2018 IPR036627 CobW-like, C-terminal domain superfamily MIM_c05090 bc8edc6141a2e631d8aae343bc94f8c8 371 SMART SM00833 274 368 1.3E-11 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MIM_c05090 bc8edc6141a2e631d8aae343bc94f8c8 371 Gene3D G3DSA:3.40.50.300 9 213 9.1E-71 T 12-10-2018 MIM_c02390 0816bc3c49e208dabfad40dd25ee47c6 153 Pfam PF09278 MerR, DNA binding 55 120 1.8E-14 T 12-10-2018 IPR015358 Transcription regulator MerR, DNA binding MIM_c02390 0816bc3c49e208dabfad40dd25ee47c6 153 SMART SM00422 13 81 3.9E-24 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MIM_c02390 0816bc3c49e208dabfad40dd25ee47c6 153 ProSitePatterns PS00552 MerR-type HTH domain signature. 16 38 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MIM_c02390 0816bc3c49e208dabfad40dd25ee47c6 153 Gene3D G3DSA:1.10.1660.10 3 136 2.1E-31 T 12-10-2018 MIM_c02390 0816bc3c49e208dabfad40dd25ee47c6 153 SUPERFAMILY SSF46955 13 137 2.45E-27 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily MIM_c02390 0816bc3c49e208dabfad40dd25ee47c6 153 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 13 149 3.7E-67 T 12-10-2018 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 MIM_c02390 0816bc3c49e208dabfad40dd25ee47c6 153 Pfam PF00376 MerR family regulatory protein 14 50 6.3E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MIM_c02390 0816bc3c49e208dabfad40dd25ee47c6 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 25 2.4E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MIM_c02390 0816bc3c49e208dabfad40dd25ee47c6 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 25 38 2.4E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MIM_c02390 0816bc3c49e208dabfad40dd25ee47c6 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 48 68 2.4E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MIM_c28790 79cacbe219383c28ec21b2406e7cc0c8 390 SUPERFAMILY SSF52317 69 239 1.35E-37 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c28790 79cacbe219383c28ec21b2406e7cc0c8 390 Gene3D G3DSA:3.40.50.880 46 276 2.0E-45 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c28790 79cacbe219383c28ec21b2406e7cc0c8 390 Pfam PF01965 DJ-1/PfpI family 65 226 3.0E-16 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 MIM_c24100 5d6ea6262cf8ddf85640903084eb3d73 399 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 85 99 - T 12-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MIM_c24100 5d6ea6262cf8ddf85640903084eb3d73 399 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 6 395 50.849 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MIM_c24100 5d6ea6262cf8ddf85640903084eb3d73 399 PIRSF PIRSF001413 2 399 4.9E-160 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MIM_c24100 5d6ea6262cf8ddf85640903084eb3d73 399 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 58 382 5.4E-50 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MIM_c24100 5d6ea6262cf8ddf85640903084eb3d73 399 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 11 394 3.5E-188 T 12-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MIM_c24100 5d6ea6262cf8ddf85640903084eb3d73 399 Gene3D G3DSA:3.40.50.1100 14 210 2.5E-183 T 12-10-2018 MIM_c24100 5d6ea6262cf8ddf85640903084eb3d73 399 SUPERFAMILY SSF53686 7 394 2.1E-146 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MIM_c24100 5d6ea6262cf8ddf85640903084eb3d73 399 Gene3D G3DSA:3.40.50.1100 58 388 2.5E-183 T 12-10-2018 MIM_c38690 7323f167cb4035e5969ba4f6d3cef6af 109 SUPERFAMILY SSF55387 1 104 1.12E-29 T 12-10-2018 MIM_c38690 7323f167cb4035e5969ba4f6d3cef6af 109 ProSitePatterns PS01344 Frataxin family signature. 52 66 - T 12-10-2018 IPR020895 Frataxin conserved site Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MIM_c38690 7323f167cb4035e5969ba4f6d3cef6af 109 Gene3D G3DSA:3.30.920.10 1 108 9.4E-34 T 12-10-2018 IPR036524 Frataxin/CyaY superfamily GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MIM_c38690 7323f167cb4035e5969ba4f6d3cef6af 109 Pfam PF01491 Frataxin-like domain 1 104 2.6E-25 T 12-10-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MIM_c38690 7323f167cb4035e5969ba4f6d3cef6af 109 SMART SM01219 1 108 1.8E-35 T 12-10-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MIM_c38690 7323f167cb4035e5969ba4f6d3cef6af 109 Hamap MF_00142 Iron-sulfur cluster assembly protein CyaY [cyaY]. 1 107 22.512 T 12-10-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MIM_c38690 7323f167cb4035e5969ba4f6d3cef6af 109 TIGRFAM TIGR03421 FeS_CyaY: iron donor protein CyaY 2 106 5.5E-32 T 12-10-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MIM_c00460 19d36cbb28d279d3ffaa73768d023330 224 Gene3D G3DSA:2.30.110.10 30 154 4.9E-28 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MIM_c00460 19d36cbb28d279d3ffaa73768d023330 224 SUPERFAMILY SSF50475 38 142 4.71E-18 T 12-10-2018 MIM_c00460 19d36cbb28d279d3ffaa73768d023330 224 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 39 132 4.0E-17 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MIM_c38090 47f6ff39f26e91a89c8b03cd08c26c95 349 Pfam PF06812 ImpA, N-terminal, type VI secretion system 14 130 7.8E-30 T 12-10-2018 IPR010657 ImpA, N-terminal MIM_c38090 47f6ff39f26e91a89c8b03cd08c26c95 349 TIGRFAM TIGR03363 VI_chp_8: type VI secretion-associated protein, ImpA family 4 342 4.1E-66 T 12-10-2018 IPR017740 Type VI secretion system-associated, ImpA MIM_c32010 448bec762360afdaaf2fbe8d121346b4 95 PRINTS PR00297 10kDa chaperonin signature 81 94 9.8E-33 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MIM_c32010 448bec762360afdaaf2fbe8d121346b4 95 PRINTS PR00297 10kDa chaperonin signature 3 18 9.8E-33 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MIM_c32010 448bec762360afdaaf2fbe8d121346b4 95 PRINTS PR00297 10kDa chaperonin signature 60 72 9.8E-33 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MIM_c32010 448bec762360afdaaf2fbe8d121346b4 95 PRINTS PR00297 10kDa chaperonin signature 25 46 9.8E-33 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MIM_c32010 448bec762360afdaaf2fbe8d121346b4 95 SUPERFAMILY SSF50129 1 94 1.33E-33 T 12-10-2018 IPR011032 GroES-like superfamily MIM_c32010 448bec762360afdaaf2fbe8d121346b4 95 Pfam PF00166 Chaperonin 10 Kd subunit 3 94 1.3E-34 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MIM_c32010 448bec762360afdaaf2fbe8d121346b4 95 Gene3D G3DSA:2.30.33.40 1 95 1.4E-38 T 12-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 MIM_c32010 448bec762360afdaaf2fbe8d121346b4 95 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 26.356 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MIM_c32010 448bec762360afdaaf2fbe8d121346b4 95 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 12-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 MIM_c32010 448bec762360afdaaf2fbe8d121346b4 95 SMART SM00883 2 94 1.2E-53 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MIM_c26180 930e789377a7c448488a26c4f3debff4 247 SMART SM00345 17 76 4.8E-23 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c26180 930e789377a7c448488a26c4f3debff4 247 Gene3D G3DSA:3.40.1410.10 77 245 7.8E-52 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MIM_c26180 930e789377a7c448488a26c4f3debff4 247 SUPERFAMILY SSF64288 64 244 7.38E-52 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MIM_c26180 930e789377a7c448488a26c4f3debff4 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 2.8E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c26180 930e789377a7c448488a26c4f3debff4 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 2.8E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c26180 930e789377a7c448488a26c4f3debff4 247 SMART SM00866 97 237 1.4E-39 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MIM_c26180 930e789377a7c448488a26c4f3debff4 247 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 76 4.2E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c26180 930e789377a7c448488a26c4f3debff4 247 Gene3D G3DSA:1.10.10.10 5 76 2.9E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c26180 930e789377a7c448488a26c4f3debff4 247 SUPERFAMILY SSF46785 5 80 6.07E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c26180 930e789377a7c448488a26c4f3debff4 247 Pfam PF07702 UTRA domain 99 236 2.6E-41 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MIM_c14930 acde8af6e9bfff9c19e02db50933567e 434 SUPERFAMILY SSF51735 1 158 1.4E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c14930 acde8af6e9bfff9c19e02db50933567e 434 SUPERFAMILY SSF55021 353 422 3.5E-13 T 12-10-2018 MIM_c14930 acde8af6e9bfff9c19e02db50933567e 434 Gene3D G3DSA:3.40.50.720 5 340 1.7E-163 T 12-10-2018 MIM_c14930 acde8af6e9bfff9c19e02db50933567e 434 Gene3D G3DSA:3.30.70.260 349 421 1.7E-163 T 12-10-2018 MIM_c14930 acde8af6e9bfff9c19e02db50933567e 434 Pfam PF00742 Homoserine dehydrogenase 137 315 5.6E-62 T 12-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MIM_c14930 acde8af6e9bfff9c19e02db50933567e 434 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 129 7.2E-20 T 12-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 MIM_c14930 acde8af6e9bfff9c19e02db50933567e 434 Pfam PF01842 ACT domain 354 418 6.1E-15 T 12-10-2018 IPR002912 ACT domain MIM_c14930 acde8af6e9bfff9c19e02db50933567e 434 PIRSF PIRSF000098 1 433 7.3E-160 T 12-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MIM_c14930 acde8af6e9bfff9c19e02db50933567e 434 SUPERFAMILY SSF55347 137 302 1.37E-50 T 12-10-2018 MIM_c14930 acde8af6e9bfff9c19e02db50933567e 434 Gene3D G3DSA:3.30.360.10 136 348 1.7E-163 T 12-10-2018 MIM_c14930 acde8af6e9bfff9c19e02db50933567e 434 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 183 205 - T 12-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MIM_c27410 74ff779c9605a72c2b90fcc1529a416f 481 Pfam PF00171 Aldehyde dehydrogenase family 21 474 1.2E-176 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c27410 74ff779c9605a72c2b90fcc1529a416f 481 SUPERFAMILY SSF53720 5 479 3.27E-176 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c27410 74ff779c9605a72c2b90fcc1529a416f 481 Gene3D G3DSA:3.40.309.10 259 448 6.9E-193 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MIM_c27410 74ff779c9605a72c2b90fcc1529a416f 481 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MIM_c27410 74ff779c9605a72c2b90fcc1529a416f 481 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 28 474 5.4E-225 T 12-10-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 MIM_c27410 74ff779c9605a72c2b90fcc1529a416f 481 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MIM_c27410 74ff779c9605a72c2b90fcc1529a416f 481 Gene3D G3DSA:3.40.605.10 19 471 6.9E-193 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c22110 dd79bd1245d1ba851e4dcadb360419c7 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 7.0E-39 T 12-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c22110 dd79bd1245d1ba851e4dcadb360419c7 100 Gene3D G3DSA:3.30.280.10 1 100 3.3E-46 T 12-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c22110 dd79bd1245d1ba851e4dcadb360419c7 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 34.326 T 12-10-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c22110 dd79bd1245d1ba851e4dcadb360419c7 100 PIRSF PIRSF001223 1 100 5.9E-50 T 12-10-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c22110 dd79bd1245d1ba851e4dcadb360419c7 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 99 1.1E-48 T 12-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c22110 dd79bd1245d1ba851e4dcadb360419c7 100 Pfam PF00547 Urease, gamma subunit 1 99 6.9E-46 T 12-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c22110 dd79bd1245d1ba851e4dcadb360419c7 100 SUPERFAMILY SSF54111 1 99 1.1E-44 T 12-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c00930 f92899a34ee989d01a7e8ffb7fbd3208 737 Pfam PF07715 TonB-dependent Receptor Plug Domain 91 186 3.1E-16 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain MIM_c00930 f92899a34ee989d01a7e8ffb7fbd3208 737 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 94 737 9.9E-108 T 12-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 MIM_c00930 f92899a34ee989d01a7e8ffb7fbd3208 737 Pfam PF00593 TonB dependent receptor 281 735 9.1E-44 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MIM_c00930 f92899a34ee989d01a7e8ffb7fbd3208 737 Gene3D G3DSA:2.40.170.20 204 737 2.5E-86 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MIM_c00930 f92899a34ee989d01a7e8ffb7fbd3208 737 SUPERFAMILY SSF56935 46 737 6.02E-109 T 12-10-2018 MIM_c00930 f92899a34ee989d01a7e8ffb7fbd3208 737 Gene3D G3DSA:2.170.130.10 87 203 3.1E-24 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MIM_c01320 204ff313ba7791c3150f109ba60d4fec 552 SUPERFAMILY SSF46977 444 523 7.98E-15 T 12-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MIM_c01320 204ff313ba7791c3150f109ba60d4fec 552 Gene3D G3DSA:3.90.700.10 242 352 2.7E-152 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 MIM_c01320 204ff313ba7791c3150f109ba60d4fec 552 Pfam PF00890 FAD binding domain 5 386 5.1E-88 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MIM_c01320 204ff313ba7791c3150f109ba60d4fec 552 SUPERFAMILY SSF56425 232 346 4.04E-42 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 MIM_c01320 204ff313ba7791c3150f109ba60d4fec 552 Pfam PF02910 Fumarate reductase flavoprotein C-term 445 522 2.4E-8 T 12-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MIM_c01320 204ff313ba7791c3150f109ba60d4fec 552 SUPERFAMILY SSF51905 2 407 1.56E-64 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c01320 204ff313ba7791c3150f109ba60d4fec 552 Gene3D G3DSA:1.20.58.100 435 537 8.0E-20 T 12-10-2018 MIM_c01320 204ff313ba7791c3150f109ba60d4fec 552 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 3 521 1.5E-161 T 12-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 MIM_c01320 204ff313ba7791c3150f109ba60d4fec 552 Gene3D G3DSA:3.50.50.60 5 398 2.7E-152 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c01320 204ff313ba7791c3150f109ba60d4fec 552 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 191 209 2.4E-6 T 12-10-2018 MIM_c01320 204ff313ba7791c3150f109ba60d4fec 552 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 349 371 2.4E-6 T 12-10-2018 MIM_c01320 204ff313ba7791c3150f109ba60d4fec 552 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 65 84 2.4E-6 T 12-10-2018 MIM_c11390 fcb2e612fe3b46f11b7cf2da4392bf23 663 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 62 510 2.8E-137 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c11390 fcb2e612fe3b46f11b7cf2da4392bf23 663 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 286 340 - T 12-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c11390 fcb2e612fe3b46f11b7cf2da4392bf23 663 SUPERFAMILY SSF81442 49 566 9.81E-180 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c11390 fcb2e612fe3b46f11b7cf2da4392bf23 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 172 184 2.0E-93 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c11390 fcb2e612fe3b46f11b7cf2da4392bf23 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 233 252 2.0E-93 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c11390 fcb2e612fe3b46f11b7cf2da4392bf23 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 284 305 2.0E-93 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c11390 fcb2e612fe3b46f11b7cf2da4392bf23 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 330 345 2.0E-93 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c11390 fcb2e612fe3b46f11b7cf2da4392bf23 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 130 154 2.0E-93 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c11390 fcb2e612fe3b46f11b7cf2da4392bf23 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 389 407 2.0E-93 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c11390 fcb2e612fe3b46f11b7cf2da4392bf23 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 417 436 2.0E-93 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c11390 fcb2e612fe3b46f11b7cf2da4392bf23 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 204 222 2.0E-93 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c11390 fcb2e612fe3b46f11b7cf2da4392bf23 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 53 78 2.0E-93 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c11390 fcb2e612fe3b46f11b7cf2da4392bf23 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 103 126 2.0E-93 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c11390 fcb2e612fe3b46f11b7cf2da4392bf23 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 354 375 2.0E-93 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c11390 fcb2e612fe3b46f11b7cf2da4392bf23 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 467 488 2.0E-93 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c11390 fcb2e612fe3b46f11b7cf2da4392bf23 663 Gene3D G3DSA:1.20.210.10 22 571 3.5E-190 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c11390 fcb2e612fe3b46f11b7cf2da4392bf23 663 TIGRFAM TIGR02843 CyoB: cytochrome o ubiquinol oxidase, subunit I 8 652 0.0 T 12-10-2018 IPR014207 Cytochrome o ubiquinol oxidase, subunit I GO:0016682|GO:0055114 MetaCyc: PWY-7544 MIM_c04450 c962320f7ae83fbdd14bda47f19ac08a 610 SUPERFAMILY SSF56235 2 237 1.12E-70 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MIM_c04450 c962320f7ae83fbdd14bda47f19ac08a 610 Gene3D G3DSA:3.40.50.10490 252 609 1.2E-141 T 12-10-2018 MIM_c04450 c962320f7ae83fbdd14bda47f19ac08a 610 Pfam PF01380 SIS domain 464 592 1.1E-26 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MIM_c04450 c962320f7ae83fbdd14bda47f19ac08a 610 Pfam PF01380 SIS domain 292 413 9.9E-28 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MIM_c04450 c962320f7ae83fbdd14bda47f19ac08a 610 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 610 38.972 T 12-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 MIM_c04450 c962320f7ae83fbdd14bda47f19ac08a 610 Gene3D G3DSA:3.40.50.10490 448 595 1.2E-141 T 12-10-2018 MIM_c04450 c962320f7ae83fbdd14bda47f19ac08a 610 SUPERFAMILY SSF53697 248 610 3.62E-107 T 12-10-2018 MIM_c04450 c962320f7ae83fbdd14bda47f19ac08a 610 Pfam PF13522 Glutamine amidotransferase domain 62 194 3.9E-21 T 12-10-2018 MIM_c04450 c962320f7ae83fbdd14bda47f19ac08a 610 Gene3D G3DSA:3.60.20.10 2 244 6.1E-75 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MIM_c04450 c962320f7ae83fbdd14bda47f19ac08a 610 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 610 2.6E-249 T 12-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 MIM_c10130 2af6d7e363245e5e13e6c6cad3d0b456 722 Gene3D G3DSA:2.170.130.10 57 198 1.7E-31 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MIM_c10130 2af6d7e363245e5e13e6c6cad3d0b456 722 Pfam PF07715 TonB-dependent Receptor Plug Domain 82 185 7.1E-19 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain MIM_c10130 2af6d7e363245e5e13e6c6cad3d0b456 722 SUPERFAMILY SSF56935 72 722 1.53E-135 T 12-10-2018 MIM_c10130 2af6d7e363245e5e13e6c6cad3d0b456 722 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 82 721 1.8E-120 T 12-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 MIM_c10130 2af6d7e363245e5e13e6c6cad3d0b456 722 Gene3D G3DSA:2.40.170.20 199 722 1.3E-123 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MIM_c10130 2af6d7e363245e5e13e6c6cad3d0b456 722 Pfam PF00593 TonB dependent receptor 271 721 8.8E-56 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MIM_c02210 479633a9060d22ba663f05bfc6292e48 318 SUPERFAMILY SSF81345 9 314 5.49E-52 T 12-10-2018 IPR037294 ABC transporter, BtuC-like MIM_c02210 479633a9060d22ba663f05bfc6292e48 318 Gene3D G3DSA:1.10.3470.10 4 318 1.8E-51 T 12-10-2018 IPR037294 ABC transporter, BtuC-like MIM_c02210 479633a9060d22ba663f05bfc6292e48 318 Pfam PF01032 FecCD transport family 26 314 4.4E-50 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MIM_c41060 520a27d304c863abb14a257b1799c09d 309 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 12 28 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MIM_c41060 520a27d304c863abb14a257b1799c09d 309 Pfam PF00682 HMGL-like 5 278 2.1E-43 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 MIM_c41060 520a27d304c863abb14a257b1799c09d 309 Gene3D G3DSA:3.20.20.70 1 290 2.9E-102 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c41060 520a27d304c863abb14a257b1799c09d 309 SUPERFAMILY SSF51569 1 285 5.31E-64 T 12-10-2018 MIM_c41130 3ec04a5550fd387774713e2f5417b5b1 259 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 23 206 4.2E-46 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal MIM_c41130 3ec04a5550fd387774713e2f5417b5b1 259 SUPERFAMILY SSF53639 17 228 4.32E-60 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily MIM_c41130 3ec04a5550fd387774713e2f5417b5b1 259 Gene3D G3DSA:3.40.225.10 7 259 8.6E-77 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily MIM_c41130 3ec04a5550fd387774713e2f5417b5b1 259 SMART SM01007 22 206 3.7E-62 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal MIM_c27700 329414fb47067842556b779f6395b40b 182 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 22 175 30.506 T 12-10-2018 IPR033747 Class I PurE MIM_c27700 329414fb47067842556b779f6395b40b 182 Gene3D G3DSA:3.40.50.7700 9 180 3.8E-70 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 MIM_c27700 329414fb47067842556b779f6395b40b 182 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 22 170 1.3E-60 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MIM_c27700 329414fb47067842556b779f6395b40b 182 Pfam PF00731 AIR carboxylase 22 169 1.8E-60 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MIM_c27700 329414fb47067842556b779f6395b40b 182 PIRSF PIRSF001338 17 176 8.1E-63 T 12-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 MIM_c27700 329414fb47067842556b779f6395b40b 182 SMART SM01001 20 171 8.2E-93 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MIM_c27700 329414fb47067842556b779f6395b40b 182 SUPERFAMILY SSF52255 21 174 7.19E-62 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 MIM_c24410 e930df6463e51761b41d6fe9fc4ec8af 291 Gene3D G3DSA:3.40.50.1000 10 281 3.9E-73 T 12-10-2018 IPR023214 HAD superfamily MIM_c24410 e930df6463e51761b41d6fe9fc4ec8af 291 Pfam PF12710 haloacid dehalogenase-like hydrolase 76 243 5.3E-21 T 12-10-2018 MIM_c24410 e930df6463e51761b41d6fe9fc4ec8af 291 SUPERFAMILY SSF56784 64 275 2.4E-47 T 12-10-2018 IPR036412 HAD-like superfamily MIM_c24410 e930df6463e51761b41d6fe9fc4ec8af 291 Pfam PF13284 Domain of unknown function (DUF4072) 3 42 7.6E-6 T 12-10-2018 IPR025138 Domain of unknown function DUF4072 MIM_c24410 e930df6463e51761b41d6fe9fc4ec8af 291 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 74 245 1.5E-32 T 12-10-2018 MIM_c24410 e930df6463e51761b41d6fe9fc4ec8af 291 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 67 276 3.4E-70 T 12-10-2018 MIM_c36340 37366076c2b4cd059d7ddcf3d38c6e33 184 Pfam PF00565 Staphylococcal nuclease homologue 51 146 1.9E-24 T 12-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 MIM_c36340 37366076c2b4cd059d7ddcf3d38c6e33 184 SUPERFAMILY SSF50199 23 153 4.32E-38 T 12-10-2018 MIM_c36340 37366076c2b4cd059d7ddcf3d38c6e33 184 SMART SM00318 25 146 7.5E-33 T 12-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 MIM_c36340 37366076c2b4cd059d7ddcf3d38c6e33 184 ProSitePatterns PS01123 Thermonuclease family signature 1. 36 61 - T 12-10-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 MIM_c36340 37366076c2b4cd059d7ddcf3d38c6e33 184 Gene3D G3DSA:2.40.50.90 23 157 2.8E-31 T 12-10-2018 IPR035437 SNase-like, OB-fold superfamily MIM_c36340 37366076c2b4cd059d7ddcf3d38c6e33 184 ProSitePatterns PS01284 Thermonuclease family signature 2. 91 101 - T 12-10-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 MIM_c39690 8ea119fc1fb0ed5d3b7cd911eec4eab9 100 Pfam PF00276 Ribosomal protein L23 8 96 1.7E-26 T 12-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 MIM_c39690 8ea119fc1fb0ed5d3b7cd911eec4eab9 100 SUPERFAMILY SSF54189 5 97 1.47E-24 T 12-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c39690 8ea119fc1fb0ed5d3b7cd911eec4eab9 100 Gene3D G3DSA:3.30.70.330 1 100 1.4E-28 T 12-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily MIM_c39690 8ea119fc1fb0ed5d3b7cd911eec4eab9 100 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 7 99 19.82 T 12-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 MIM_c29670 9985f8ee7bd9dedd738582d2b35b713a 386 PIRSF PIRSF000729 7 376 4.3E-128 T 12-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 MIM_c29670 9985f8ee7bd9dedd738582d2b35b713a 386 Gene3D G3DSA:2.30.130.10 273 375 5.6E-33 T 12-10-2018 IPR036974 PUA domain superfamily GO:0003723 MIM_c29670 9985f8ee7bd9dedd738582d2b35b713a 386 Gene3D G3DSA:3.40.1160.10 4 270 1.1E-90 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MIM_c29670 9985f8ee7bd9dedd738582d2b35b713a 386 Hamap MF_00456 Glutamate 5-kinase [proB]. 12 268 35.905 T 12-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MIM_c29670 9985f8ee7bd9dedd738582d2b35b713a 386 PRINTS PR00474 Glutamate 5-kinase family signature 83 111 6.3E-50 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MIM_c29670 9985f8ee7bd9dedd738582d2b35b713a 386 PRINTS PR00474 Glutamate 5-kinase family signature 49 63 6.3E-50 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MIM_c29670 9985f8ee7bd9dedd738582d2b35b713a 386 PRINTS PR00474 Glutamate 5-kinase family signature 123 144 6.3E-50 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MIM_c29670 9985f8ee7bd9dedd738582d2b35b713a 386 PRINTS PR00474 Glutamate 5-kinase family signature 155 182 6.3E-50 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MIM_c29670 9985f8ee7bd9dedd738582d2b35b713a 386 PRINTS PR00474 Glutamate 5-kinase family signature 216 236 6.3E-50 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MIM_c29670 9985f8ee7bd9dedd738582d2b35b713a 386 ProSitePatterns PS00902 Glutamate 5-kinase signature. 214 231 - T 12-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MIM_c29670 9985f8ee7bd9dedd738582d2b35b713a 386 TIGRFAM TIGR01027 proB: glutamate 5-kinase 12 374 2.1E-127 T 12-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MIM_c29670 9985f8ee7bd9dedd738582d2b35b713a 386 SMART SM00359 284 367 1.1E-14 T 12-10-2018 IPR002478 PUA domain GO:0003723 MIM_c29670 9985f8ee7bd9dedd738582d2b35b713a 386 Pfam PF00696 Amino acid kinase family 12 241 5.4E-43 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 MIM_c29670 9985f8ee7bd9dedd738582d2b35b713a 386 Pfam PF01472 PUA domain 284 358 2.0E-20 T 12-10-2018 IPR002478 PUA domain GO:0003723 MIM_c29670 9985f8ee7bd9dedd738582d2b35b713a 386 SUPERFAMILY SSF88697 284 374 1.64E-24 T 12-10-2018 IPR015947 PUA-like superfamily MIM_c29670 9985f8ee7bd9dedd738582d2b35b713a 386 SUPERFAMILY SSF53633 12 261 1.7E-68 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MIM_c30830 b59fa47024473cb537de3310fba387c4 343 Pfam PF01032 FecCD transport family 31 340 1.4E-82 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MIM_c30830 b59fa47024473cb537de3310fba387c4 343 Gene3D G3DSA:1.10.3470.10 17 343 4.1E-87 T 12-10-2018 IPR037294 ABC transporter, BtuC-like MIM_c30830 b59fa47024473cb537de3310fba387c4 343 SUPERFAMILY SSF81345 12 340 3.92E-74 T 12-10-2018 IPR037294 ABC transporter, BtuC-like MIM_c23820 0be35c0032ea44f7aa20fd786897b979 268 ProSitePatterns PS00501 Signal peptidases I serine active site. 73 80 - T 12-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 MIM_c23820 0be35c0032ea44f7aa20fd786897b979 268 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 49 257 2.4E-52 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MIM_c23820 0be35c0032ea44f7aa20fd786897b979 268 SUPERFAMILY SSF51306 62 264 5.08E-70 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily MIM_c23820 0be35c0032ea44f7aa20fd786897b979 268 ProSitePatterns PS00761 Signal peptidases I signature 3. 223 236 - T 12-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 MIM_c23820 0be35c0032ea44f7aa20fd786897b979 268 Gene3D G3DSA:2.170.230.10 139 217 3.3E-73 T 12-10-2018 MIM_c23820 0be35c0032ea44f7aa20fd786897b979 268 Pfam PF10502 Signal peptidase, peptidase S26 217 255 2.4E-6 T 12-10-2018 IPR019533 Peptidase S26 MIM_c23820 0be35c0032ea44f7aa20fd786897b979 268 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 64 80 7.9E-26 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MIM_c23820 0be35c0032ea44f7aa20fd786897b979 268 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 128 140 7.9E-26 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MIM_c23820 0be35c0032ea44f7aa20fd786897b979 268 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 218 237 7.9E-26 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MIM_c23820 0be35c0032ea44f7aa20fd786897b979 268 Pfam PF00717 Peptidase S24-like 70 152 1.1E-21 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MIM_c23820 0be35c0032ea44f7aa20fd786897b979 268 Gene3D G3DSA:2.10.109.10 62 258 3.3E-73 T 12-10-2018 MIM_c23820 0be35c0032ea44f7aa20fd786897b979 268 ProSitePatterns PS00760 Signal peptidases I lysine active site. 130 142 - T 12-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 MIM_c23650 5ce133ef916b766e2a594dcc9a97cb36 773 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 72 180 3.4E-18 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c23650 5ce133ef916b766e2a594dcc9a97cb36 773 SUPERFAMILY SSF56645 67 301 1.44E-44 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c23650 5ce133ef916b766e2a594dcc9a97cb36 773 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 307 454 7.3E-16 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MIM_c23650 5ce133ef916b766e2a594dcc9a97cb36 773 Pfam PF09317 Domain of unknown function (DUF1974) 461 749 7.7E-109 T 12-10-2018 IPR015396 Acyl-CoA dehydrogenase, C-termina, bacterial type GO:0003995|GO:0033539|GO:0055114 KEGG: 00071+1.3.8.8+1.3.8.7|KEGG: 00280+1.3.8.7|KEGG: 00410+1.3.8.7|KEGG: 00640+1.3.8.7|MetaCyc: PWY-7094|MetaCyc: PWY-7654 MIM_c23650 5ce133ef916b766e2a594dcc9a97cb36 773 Gene3D G3DSA:1.20.140.10 307 454 1.3E-95 T 12-10-2018 MIM_c23650 5ce133ef916b766e2a594dcc9a97cb36 773 Gene3D G3DSA:2.40.110.10 183 306 1.3E-95 T 12-10-2018 MIM_c23650 5ce133ef916b766e2a594dcc9a97cb36 773 SUPERFAMILY SSF47203 307 454 1.93E-27 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c23650 5ce133ef916b766e2a594dcc9a97cb36 773 Gene3D G3DSA:1.10.540.10 70 182 1.3E-95 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c00270 3a14f19dc09886f2686e2514f8f4cc2c 322 Gene3D G3DSA:3.40.190.150 27 313 6.0E-97 T 12-10-2018 MIM_c00270 3a14f19dc09886f2686e2514f8f4cc2c 322 SUPERFAMILY SSF53850 105 284 2.3E-9 T 12-10-2018 MIM_c00270 3a14f19dc09886f2686e2514f8f4cc2c 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 319 2.8E-67 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c00270 3a14f19dc09886f2686e2514f8f4cc2c 322 Gene3D G3DSA:3.40.190.10 125 248 6.0E-97 T 12-10-2018 MIM_c00270 3a14f19dc09886f2686e2514f8f4cc2c 322 PIRSF PIRSF017082 1 322 1.5E-78 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c07350 41fd69940e389bbf7d8a0be93fd32455 346 PIRSF PIRSF000114 6 346 9.4E-95 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MIM_c07350 41fd69940e389bbf7d8a0be93fd32455 346 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 10 337 34.06 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MIM_c07350 41fd69940e389bbf7d8a0be93fd32455 346 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 196 335 1.1E-45 T 12-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MIM_c07350 41fd69940e389bbf7d8a0be93fd32455 346 Gene3D G3DSA:3.40.50.720 7 203 6.4E-52 T 12-10-2018 MIM_c07350 41fd69940e389bbf7d8a0be93fd32455 346 SUPERFAMILY SSF51735 11 196 2.36E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c07350 41fd69940e389bbf7d8a0be93fd32455 346 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 12 173 1.3E-37 T 12-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MIM_c07350 41fd69940e389bbf7d8a0be93fd32455 346 Gene3D G3DSA:1.10.1040.10 205 346 9.2E-46 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MIM_c07350 41fd69940e389bbf7d8a0be93fd32455 346 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 254 271 1.4E-36 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MIM_c07350 41fd69940e389bbf7d8a0be93fd32455 346 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 14 31 1.4E-36 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MIM_c07350 41fd69940e389bbf7d8a0be93fd32455 346 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 149 169 1.4E-36 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MIM_c07350 41fd69940e389bbf7d8a0be93fd32455 346 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 214 238 1.4E-36 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MIM_c07350 41fd69940e389bbf7d8a0be93fd32455 346 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 189 213 1.4E-36 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MIM_c07350 41fd69940e389bbf7d8a0be93fd32455 346 SUPERFAMILY SSF48179 196 346 6.12E-50 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c07350 41fd69940e389bbf7d8a0be93fd32455 346 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 204 225 - T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MIM_c06030 3f8a16c1d9f7bd5fec9e9a79be3ada77 415 Gene3D G3DSA:3.30.9.10 138 356 2.8E-44 T 12-10-2018 MIM_c06030 3f8a16c1d9f7bd5fec9e9a79be3ada77 415 Gene3D G3DSA:3.50.50.60 8 54 7.0E-13 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c06030 3f8a16c1d9f7bd5fec9e9a79be3ada77 415 Gene3D G3DSA:3.50.50.60 123 397 2.8E-44 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c06030 3f8a16c1d9f7bd5fec9e9a79be3ada77 415 SUPERFAMILY SSF54373 272 357 3.27E-8 T 12-10-2018 MIM_c06030 3f8a16c1d9f7bd5fec9e9a79be3ada77 415 SUPERFAMILY SSF51905 7 414 8.55E-51 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c06030 3f8a16c1d9f7bd5fec9e9a79be3ada77 415 Pfam PF01266 FAD dependent oxidoreductase 8 395 5.0E-53 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MIM_c01570 903e0789365a5927fc4653e27e00f6ae 289 SUPERFAMILY SSF161098 87 272 8.5E-33 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c01570 903e0789365a5927fc4653e27e00f6ae 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 281 2.1E-26 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c01570 903e0789365a5927fc4653e27e00f6ae 289 Gene3D G3DSA:1.10.3720.10 86 282 8.2E-25 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c22080 b3cb0ed686e7b00e745baabe97074c91 282 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 260 281 6.6E-8 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal MIM_c22080 b3cb0ed686e7b00e745baabe97074c91 282 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 34 282 1.7E-101 T 12-10-2018 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD MIM_c22080 b3cb0ed686e7b00e745baabe97074c91 282 ProSitePatterns PS00211 ABC transporters family signature. 181 195 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c22080 b3cb0ed686e7b00e745baabe97074c91 282 Gene3D G3DSA:3.40.50.300 34 280 3.5E-49 T 12-10-2018 MIM_c22080 b3cb0ed686e7b00e745baabe97074c91 282 Pfam PF00005 ABC transporter 51 209 8.0E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c22080 b3cb0ed686e7b00e745baabe97074c91 282 SUPERFAMILY SSF52540 34 280 1.49E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c07520 6bcf283c8b1afd40a73f5b41981d8d96 466 Gene3D G3DSA:3.40.50.300 81 349 1.6E-112 T 12-10-2018 MIM_c07520 6bcf283c8b1afd40a73f5b41981d8d96 466 SUPERFAMILY SSF47917 350 465 2.43E-53 T 12-10-2018 MIM_c07520 6bcf283c8b1afd40a73f5b41981d8d96 466 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 78 2.2E-17 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MIM_c07520 6bcf283c8b1afd40a73f5b41981d8d96 466 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 465 56.107 T 12-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 MIM_c07520 6bcf283c8b1afd40a73f5b41981d8d96 466 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 465 7.4E-248 T 12-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 MIM_c07520 6bcf283c8b1afd40a73f5b41981d8d96 466 Gene3D G3DSA:1.10.1140.10 350 466 4.7E-58 T 12-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MIM_c07520 6bcf283c8b1afd40a73f5b41981d8d96 466 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 338 347 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MIM_c07520 6bcf283c8b1afd40a73f5b41981d8d96 466 SMART SM00382 147 324 0.0047 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c07520 6bcf283c8b1afd40a73f5b41981d8d96 466 SUPERFAMILY SSF52540 82 352 5.67E-89 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c07520 6bcf283c8b1afd40a73f5b41981d8d96 466 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 135 347 1.1E-63 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MIM_c07520 6bcf283c8b1afd40a73f5b41981d8d96 466 Gene3D G3DSA:2.40.10.170 2 80 7.9E-26 T 12-10-2018 MIM_c07520 6bcf283c8b1afd40a73f5b41981d8d96 466 SUPERFAMILY SSF50615 3 78 8.37E-23 T 12-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MIM_c34950 f2616e0bf7071594bf9167e3983cec23 540 Gene3D G3DSA:3.40.250.10 132 238 3.0E-21 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily MIM_c34950 f2616e0bf7071594bf9167e3983cec23 540 Pfam PF00581 Rhodanese-like domain 14 106 1.6E-5 T 12-10-2018 IPR001763 Rhodanese-like domain MIM_c34950 f2616e0bf7071594bf9167e3983cec23 540 Pfam PF00581 Rhodanese-like domain 395 480 2.5E-5 T 12-10-2018 IPR001763 Rhodanese-like domain MIM_c34950 f2616e0bf7071594bf9167e3983cec23 540 Pfam PF00581 Rhodanese-like domain 144 230 4.1E-9 T 12-10-2018 IPR001763 Rhodanese-like domain MIM_c34950 f2616e0bf7071594bf9167e3983cec23 540 Pfam PF00581 Rhodanese-like domain 279 353 3.2E-6 T 12-10-2018 IPR001763 Rhodanese-like domain MIM_c34950 f2616e0bf7071594bf9167e3983cec23 540 Gene3D G3DSA:3.40.250.10 383 488 5.6E-12 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily MIM_c34950 f2616e0bf7071594bf9167e3983cec23 540 SUPERFAMILY SSF52821 262 354 5.63E-16 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily MIM_c34950 f2616e0bf7071594bf9167e3983cec23 540 SMART SM00450 13 110 3.8E-4 T 12-10-2018 IPR001763 Rhodanese-like domain MIM_c34950 f2616e0bf7071594bf9167e3983cec23 540 SMART SM00450 136 234 6.1E-9 T 12-10-2018 IPR001763 Rhodanese-like domain MIM_c34950 f2616e0bf7071594bf9167e3983cec23 540 SMART SM00450 272 361 2.8 T 12-10-2018 IPR001763 Rhodanese-like domain MIM_c34950 f2616e0bf7071594bf9167e3983cec23 540 SMART SM00450 383 484 2.6E-4 T 12-10-2018 IPR001763 Rhodanese-like domain MIM_c34950 f2616e0bf7071594bf9167e3983cec23 540 SUPERFAMILY SSF52821 382 540 6.68E-15 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily MIM_c34950 f2616e0bf7071594bf9167e3983cec23 540 Gene3D G3DSA:3.40.250.10 10 116 7.0E-18 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily MIM_c34950 f2616e0bf7071594bf9167e3983cec23 540 Gene3D G3DSA:3.40.250.10 268 355 1.5E-15 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily MIM_c34950 f2616e0bf7071594bf9167e3983cec23 540 SUPERFAMILY SSF52821 113 240 3.67E-29 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily MIM_c34950 f2616e0bf7071594bf9167e3983cec23 540 SUPERFAMILY SSF52821 11 126 6.29E-23 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily MIM_c09310 3e9345fed804f4b7338a6666ad55e0c5 253 Gene3D G3DSA:3.40.190.10 34 248 1.0E-80 T 12-10-2018 MIM_c09310 3e9345fed804f4b7338a6666ad55e0c5 253 SUPERFAMILY SSF53850 9 250 1.76E-77 T 12-10-2018 MIM_c09310 3e9345fed804f4b7338a6666ad55e0c5 253 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 32 250 1.2E-72 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c09310 3e9345fed804f4b7338a6666ad55e0c5 253 SMART SM00079 31 250 4.4E-10 T 12-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 MIM_c09310 3e9345fed804f4b7338a6666ad55e0c5 253 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 53 66 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site MIM_c09310 3e9345fed804f4b7338a6666ad55e0c5 253 Gene3D G3DSA:3.40.190.10 115 211 1.0E-80 T 12-10-2018 MIM_c09310 3e9345fed804f4b7338a6666ad55e0c5 253 SMART SM00062 31 251 2.0E-72 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c18020 0de626aba63b49d4eb08c94e7e0d2dc4 634 Gene3D G3DSA:3.90.980.10 108 237 8.3E-37 T 12-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily MIM_c18020 0de626aba63b49d4eb08c94e7e0d2dc4 634 SMART SM00766 503 627 5.8E-6 T 12-10-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 MIM_c18020 0de626aba63b49d4eb08c94e7e0d2dc4 634 SUPERFAMILY SSF57783 2 98 1.04E-34 T 12-10-2018 MIM_c18020 0de626aba63b49d4eb08c94e7e0d2dc4 634 Pfam PF08278 DNA primase DnaG DnaB-binding 505 625 6.4E-7 T 12-10-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 MIM_c18020 0de626aba63b49d4eb08c94e7e0d2dc4 634 Pfam PF01807 CHC2 zinc finger 3 98 1.4E-36 T 12-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MIM_c18020 0de626aba63b49d4eb08c94e7e0d2dc4 634 PIRSF PIRSF002811 1 632 6.1E-137 T 12-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 MIM_c18020 0de626aba63b49d4eb08c94e7e0d2dc4 634 TIGRFAM TIGR01391 dnaG: DNA primase 2 414 2.8E-131 T 12-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 MIM_c18020 0de626aba63b49d4eb08c94e7e0d2dc4 634 SMART SM00400 33 87 1.2E-33 T 12-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MIM_c18020 0de626aba63b49d4eb08c94e7e0d2dc4 634 Gene3D G3DSA:3.90.580.10 1 99 3.6E-37 T 12-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 MIM_c18020 0de626aba63b49d4eb08c94e7e0d2dc4 634 Hamap MF_00974 DNA primase [dnaG]. 1 631 26.52 T 12-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 MIM_c18020 0de626aba63b49d4eb08c94e7e0d2dc4 634 Pfam PF08275 DNA primase catalytic core, N-terminal domain 134 247 6.2E-36 T 12-10-2018 IPR013264 DNA primase, catalytic core, N-terminal MIM_c18020 0de626aba63b49d4eb08c94e7e0d2dc4 634 Pfam PF10410 DnaB-helicase binding domain of primase 367 419 7.7E-11 T 12-10-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 MIM_c18020 0de626aba63b49d4eb08c94e7e0d2dc4 634 Pfam PF13662 Toprim domain 257 320 4.5E-11 T 12-10-2018 IPR006171 TOPRIM domain MIM_c18020 0de626aba63b49d4eb08c94e7e0d2dc4 634 Gene3D G3DSA:1.20.50.20 365 422 6.6E-5 T 12-10-2018 MIM_c18020 0de626aba63b49d4eb08c94e7e0d2dc4 634 SMART SM00493 256 327 5.3E-15 T 12-10-2018 IPR006171 TOPRIM domain MIM_c18020 0de626aba63b49d4eb08c94e7e0d2dc4 634 Gene3D G3DSA:3.40.1360.10 238 363 1.7E-36 T 12-10-2018 MIM_c18020 0de626aba63b49d4eb08c94e7e0d2dc4 634 SUPERFAMILY SSF56731 119 419 6.8E-97 T 12-10-2018 MIM_c28610 d7ab32cc4206caf52b8dd16794c74159 155 PRINTS PR01438 Universal stress protein signature 108 120 1.3E-16 T 12-10-2018 IPR006015 Universal stress protein A MIM_c28610 d7ab32cc4206caf52b8dd16794c74159 155 PRINTS PR01438 Universal stress protein signature 126 148 1.3E-16 T 12-10-2018 IPR006015 Universal stress protein A MIM_c28610 d7ab32cc4206caf52b8dd16794c74159 155 PRINTS PR01438 Universal stress protein signature 2 20 1.3E-16 T 12-10-2018 IPR006015 Universal stress protein A MIM_c28610 d7ab32cc4206caf52b8dd16794c74159 155 Pfam PF00582 Universal stress protein family 1 148 6.0E-29 T 12-10-2018 IPR006016 UspA MIM_c28610 d7ab32cc4206caf52b8dd16794c74159 155 Gene3D G3DSA:3.40.50.620 1 148 2.0E-35 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c28610 d7ab32cc4206caf52b8dd16794c74159 155 SUPERFAMILY SSF52402 2 148 3.77E-34 T 12-10-2018 MIM_c22390 6e61967184f30fc22bbb516c09a77ef5 537 Gene3D G3DSA:3.30.300.310 435 536 2.4E-31 T 12-10-2018 MIM_c22390 6e61967184f30fc22bbb516c09a77ef5 537 SUPERFAMILY SSF56801 20 533 7.72E-138 T 12-10-2018 MIM_c22390 6e61967184f30fc22bbb516c09a77ef5 537 ProSitePatterns PS00455 Putative AMP-binding domain signature. 182 193 - T 12-10-2018 IPR020845 AMP-binding, conserved site MIM_c22390 6e61967184f30fc22bbb516c09a77ef5 537 Pfam PF00501 AMP-binding enzyme 34 435 1.1E-84 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MIM_c22390 6e61967184f30fc22bbb516c09a77ef5 537 Gene3D G3DSA:3.40.50.12780 13 434 3.2E-101 T 12-10-2018 MIM_c22390 6e61967184f30fc22bbb516c09a77ef5 537 Pfam PF13193 AMP-binding enzyme C-terminal domain 446 521 1.0E-18 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MIM_c19420 a78cadefcccb0300daba1ef521d2ac3b 205 Pfam PF03938 Outer membrane protein (OmpH-like) 48 201 3.4E-36 T 12-10-2018 IPR005632 Chaperone protein Skp GO:0051082 MIM_c19420 a78cadefcccb0300daba1ef521d2ac3b 205 SMART SM00935 23 202 9.2E-55 T 12-10-2018 IPR005632 Chaperone protein Skp GO:0051082 MIM_c19420 a78cadefcccb0300daba1ef521d2ac3b 205 SUPERFAMILY SSF111384 62 202 3.01E-36 T 12-10-2018 MIM_c19420 a78cadefcccb0300daba1ef521d2ac3b 205 Gene3D G3DSA:3.30.910.20 61 202 3.2E-40 T 12-10-2018 IPR024930 Skp domain superfamily MIM_c19420 a78cadefcccb0300daba1ef521d2ac3b 205 PIRSF PIRSF002094 39 205 2.8E-46 T 12-10-2018 IPR005632 Chaperone protein Skp GO:0051082 MIM_c06570 a5f56acf0c179680546ac23f55c893dc 1274 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 143 254 2.2E-47 T 12-10-2018 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 MIM_c06570 a5f56acf0c179680546ac23f55c893dc 1274 SUPERFAMILY SSF51730 257 602 1.06E-118 T 12-10-2018 IPR029041 FAD-linked oxidoreductase-like MIM_c06570 a5f56acf0c179680546ac23f55c893dc 1274 Gene3D G3DSA:3.20.20.220 211 598 1.2E-150 T 12-10-2018 MIM_c06570 a5f56acf0c179680546ac23f55c893dc 1274 Gene3D G3DSA:3.40.309.10 881 1073 3.4E-148 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MIM_c06570 a5f56acf0c179680546ac23f55c893dc 1274 Gene3D G3DSA:1.10.1220.10 12 53 4.0E-10 T 12-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 MIM_c06570 a5f56acf0c179680546ac23f55c893dc 1274 SUPERFAMILY SSF53720 641 1102 3.8E-130 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c06570 a5f56acf0c179680546ac23f55c893dc 1274 Pfam PF00171 Aldehyde dehydrogenase family 655 1097 2.1E-118 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c06570 a5f56acf0c179680546ac23f55c893dc 1274 Gene3D G3DSA:1.20.5.550 88 137 1.7E-15 T 12-10-2018 IPR024090 Proline dehydrogenase PutA, domain I GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 MIM_c06570 a5f56acf0c179680546ac23f55c893dc 1274 Pfam PF01619 Proline dehydrogenase 265 561 7.4E-100 T 12-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 MIM_c06570 a5f56acf0c179680546ac23f55c893dc 1274 PIRSF PIRSF000197 76 1274 0.0 T 12-10-2018 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 MIM_c06570 a5f56acf0c179680546ac23f55c893dc 1274 SUPERFAMILY SSF47598 4 46 3.33E-7 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 MIM_c06570 a5f56acf0c179680546ac23f55c893dc 1274 SUPERFAMILY SSF81935 89 255 3.14E-62 T 12-10-2018 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 MIM_c06570 a5f56acf0c179680546ac23f55c893dc 1274 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 906 917 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MIM_c06570 a5f56acf0c179680546ac23f55c893dc 1274 Gene3D G3DSA:3.40.605.10 640 1102 3.4E-148 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c06570 a5f56acf0c179680546ac23f55c893dc 1274 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 607 1102 4.0E-234 T 12-10-2018 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 MIM_c39050 c5fef2153162153642f573d0ab173a5e 131 SUPERFAMILY SSF56047 2 130 4.19E-48 T 12-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39050 c5fef2153162153642f573d0ab173a5e 131 ProSitePatterns PS00053 Ribosomal protein S8 signature. 101 118 - T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39050 c5fef2153162153642f573d0ab173a5e 131 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 131 32.704 T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39050 c5fef2153162153642f573d0ab173a5e 131 Pfam PF00410 Ribosomal protein S8 5 130 7.8E-51 T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39050 c5fef2153162153642f573d0ab173a5e 131 Gene3D G3DSA:3.30.1490.10 74 131 3.3E-24 T 12-10-2018 MIM_c39050 c5fef2153162153642f573d0ab173a5e 131 Gene3D G3DSA:3.30.1370.30 2 73 7.0E-29 T 12-10-2018 MIM_c02270 235c1169071975e6192e0e984ab5ce2b 666 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 343 356 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MIM_c02270 235c1169071975e6192e0e984ab5ce2b 666 Gene3D G3DSA:3.40.50.300 322 491 3.0E-54 T 12-10-2018 MIM_c02270 235c1169071975e6192e0e984ab5ce2b 666 Gene3D G3DSA:1.10.10.60 617 662 4.2E-12 T 12-10-2018 MIM_c02270 235c1169071975e6192e0e984ab5ce2b 666 SUPERFAMILY SSF52540 322 560 6.15E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c02270 235c1169071975e6192e0e984ab5ce2b 666 Gene3D G3DSA:3.30.450.40 6 191 9.3E-48 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c02270 235c1169071975e6192e0e984ab5ce2b 666 SUPERFAMILY SSF46689 608 660 3.94E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c02270 235c1169071975e6192e0e984ab5ce2b 666 Gene3D G3DSA:1.10.8.60 495 564 1.5E-9 T 12-10-2018 MIM_c02270 235c1169071975e6192e0e984ab5ce2b 666 SMART SM00382 339 483 5.8E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c02270 235c1169071975e6192e0e984ab5ce2b 666 Pfam PF01590 GAF domain 79 190 7.4E-5 T 12-10-2018 IPR003018 GAF domain GO:0005515 MIM_c02270 235c1169071975e6192e0e984ab5ce2b 666 Pfam PF02954 Bacterial regulatory protein, Fis family 621 659 5.0E-9 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MIM_c02270 235c1169071975e6192e0e984ab5ce2b 666 Pfam PF00158 Sigma-54 interaction domain 324 483 1.3E-58 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MIM_c02270 235c1169071975e6192e0e984ab5ce2b 666 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 644 664 1.9E-5 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MIM_c02270 235c1169071975e6192e0e984ab5ce2b 666 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 627 644 1.9E-5 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MIM_c27560 65e644de9e6fa6c551e96df53d796498 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 47 63 5.8E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c27560 65e644de9e6fa6c551e96df53d796498 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 79 5.8E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c27560 65e644de9e6fa6c551e96df53d796498 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 5.8E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c27560 65e644de9e6fa6c551e96df53d796498 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 133 5.8E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c27560 65e644de9e6fa6c551e96df53d796498 155 SUPERFAMILY SSF46785 5 138 3.67E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c27560 65e644de9e6fa6c551e96df53d796498 155 Gene3D G3DSA:1.10.10.10 1 135 1.3E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c27560 65e644de9e6fa6c551e96df53d796498 155 Pfam PF12802 MarR family 29 87 1.4E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c27560 65e644de9e6fa6c551e96df53d796498 155 SMART SM00347 23 123 5.6E-16 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c35400 033d5058b825cdfa19130c61f69fe27f 503 SUPERFAMILY SSF51556 21 480 6.97E-37 T 12-10-2018 IPR032466 Metal-dependent hydrolase MIM_c35400 033d5058b825cdfa19130c61f69fe27f 503 Pfam PF04909 Amidohydrolase 37 320 2.4E-14 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MIM_c00500 99dcbd357c82136a8a9f174ab65be975 574 SUPERFAMILY SSF52467 165 365 1.64E-34 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MIM_c00500 99dcbd357c82136a8a9f174ab65be975 574 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 435 454 - T 12-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 MIM_c00500 99dcbd357c82136a8a9f174ab65be975 574 SUPERFAMILY SSF52518 4 191 9.68E-56 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c00500 99dcbd357c82136a8a9f174ab65be975 574 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 202 336 3.3E-27 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MIM_c00500 99dcbd357c82136a8a9f174ab65be975 574 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 13 178 1.0E-52 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MIM_c00500 99dcbd357c82136a8a9f174ab65be975 574 Gene3D G3DSA:3.40.50.1220 196 363 5.2E-32 T 12-10-2018 MIM_c00500 99dcbd357c82136a8a9f174ab65be975 574 Gene3D G3DSA:3.40.50.970 370 568 7.5E-57 T 12-10-2018 MIM_c00500 99dcbd357c82136a8a9f174ab65be975 574 Gene3D G3DSA:3.40.50.970 2 181 7.0E-61 T 12-10-2018 MIM_c00500 99dcbd357c82136a8a9f174ab65be975 574 SUPERFAMILY SSF52518 377 551 2.14E-56 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c00500 99dcbd357c82136a8a9f174ab65be975 574 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 399 544 3.7E-41 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MIM_c18030 288d3204a83b0fb9957a4d87f8be173c 837 Gene3D G3DSA:1.10.601.10 347 671 8.0E-123 T 12-10-2018 MIM_c18030 288d3204a83b0fb9957a4d87f8be173c 837 SUPERFAMILY SSF88659 732 833 9.38E-26 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MIM_c18030 288d3204a83b0fb9957a4d87f8be173c 837 Pfam PF03979 Sigma-70 factor, region 1.1 236 315 6.6E-28 T 12-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 MIM_c18030 288d3204a83b0fb9957a4d87f8be173c 837 PRINTS PR00046 Major sigma-70 factor signature 795 810 1.2E-30 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MIM_c18030 288d3204a83b0fb9957a4d87f8be173c 837 PRINTS PR00046 Major sigma-70 factor signature 810 821 1.2E-30 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MIM_c18030 288d3204a83b0fb9957a4d87f8be173c 837 PRINTS PR00046 Major sigma-70 factor signature 774 786 1.2E-30 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MIM_c18030 288d3204a83b0fb9957a4d87f8be173c 837 PRINTS PR00046 Major sigma-70 factor signature 650 658 1.2E-30 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MIM_c18030 288d3204a83b0fb9957a4d87f8be173c 837 PRINTS PR00046 Major sigma-70 factor signature 626 639 1.2E-30 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MIM_c18030 288d3204a83b0fb9957a4d87f8be173c 837 Pfam PF00140 Sigma-70 factor, region 1.2 332 364 1.2E-13 T 12-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MIM_c18030 288d3204a83b0fb9957a4d87f8be173c 837 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 795 821 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MIM_c18030 288d3204a83b0fb9957a4d87f8be173c 837 SUPERFAMILY SSF88659 675 749 1.89E-18 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MIM_c18030 288d3204a83b0fb9957a4d87f8be173c 837 Gene3D G3DSA:1.10.220.120 233 296 2.8E-27 T 12-10-2018 MIM_c18030 288d3204a83b0fb9957a4d87f8be173c 837 Gene3D G3DSA:1.10.10.10 675 750 1.3E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c18030 288d3204a83b0fb9957a4d87f8be173c 837 Gene3D G3DSA:1.10.10.10 752 836 3.6E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c18030 288d3204a83b0fb9957a4d87f8be173c 837 Pfam PF04545 Sigma-70, region 4 770 823 1.1E-18 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 MIM_c18030 288d3204a83b0fb9957a4d87f8be173c 837 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 626 639 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MIM_c18030 288d3204a83b0fb9957a4d87f8be173c 837 Pfam PF04539 Sigma-70 region 3 681 755 1.8E-23 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 MIM_c18030 288d3204a83b0fb9957a4d87f8be173c 837 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 598 823 1.9E-39 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MIM_c18030 288d3204a83b0fb9957a4d87f8be173c 837 Pfam PF04542 Sigma-70 region 2 602 671 2.7E-21 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MIM_c18030 288d3204a83b0fb9957a4d87f8be173c 837 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 229 835 41.772 T 12-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 MIM_c18030 288d3204a83b0fb9957a4d87f8be173c 837 SUPERFAMILY SSF88946 349 669 1.16E-96 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MIM_c18030 288d3204a83b0fb9957a4d87f8be173c 837 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 598 834 3.3E-118 T 12-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 MIM_c18030 288d3204a83b0fb9957a4d87f8be173c 837 Pfam PF04546 Sigma-70, non-essential region 373 571 2.0E-61 T 12-10-2018 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MIM_c26300 c842e995b541fffa66781dc6455ef47c 646 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 97 103 - T 12-10-2018 IPR014762 DNA mismatch repair, conserved site MIM_c26300 c842e995b541fffa66781dc6455ef47c 646 SMART SM00853 459 602 2.7E-50 T 12-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 MIM_c26300 c842e995b541fffa66781dc6455ef47c 646 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 28 130 2.6E-14 T 12-10-2018 MIM_c26300 c842e995b541fffa66781dc6455ef47c 646 Gene3D G3DSA:3.30.1370.100 502 597 2.6E-58 T 12-10-2018 MIM_c26300 c842e995b541fffa66781dc6455ef47c 646 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 208 325 7.5E-36 T 12-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 MIM_c26300 c842e995b541fffa66781dc6455ef47c 646 Gene3D G3DSA:3.30.565.10 6 211 9.7E-66 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c26300 c842e995b541fffa66781dc6455ef47c 646 SUPERFAMILY SSF118116 454 644 4.58E-58 T 12-10-2018 IPR037198 MutL, C-terminal domain superfamily MIM_c26300 c842e995b541fffa66781dc6455ef47c 646 Gene3D G3DSA:2.30.42.20 461 639 2.6E-58 T 12-10-2018 MIM_c26300 c842e995b541fffa66781dc6455ef47c 646 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 6 306 1.7E-90 T 12-10-2018 IPR002099 DNA mismatch repair protein family, N-terminal GO:0005524|GO:0006298|GO:0030983 MIM_c26300 c842e995b541fffa66781dc6455ef47c 646 SMART SM01340 208 326 1.2E-54 T 12-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 MIM_c26300 c842e995b541fffa66781dc6455ef47c 646 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 5 642 27.28 T 12-10-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 MIM_c26300 c842e995b541fffa66781dc6455ef47c 646 SUPERFAMILY SSF55874 5 201 2.36E-51 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c26300 c842e995b541fffa66781dc6455ef47c 646 SUPERFAMILY SSF54211 190 326 4.17E-35 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MIM_c26300 c842e995b541fffa66781dc6455ef47c 646 Gene3D G3DSA:3.30.230.10 213 325 3.1E-35 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MIM_c26300 c842e995b541fffa66781dc6455ef47c 646 Pfam PF08676 MutL C terminal dimerisation domain 455 602 2.1E-47 T 12-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 MIM_c01970 3a82d593f379a6072790b780a2f0d510 220 Gene3D G3DSA:3.40.430.10 1 194 9.9E-36 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MIM_c01970 3a82d593f379a6072790b780a2f0d510 220 SUPERFAMILY SSF53597 2 194 6.49E-24 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MIM_c01970 3a82d593f379a6072790b780a2f0d510 220 Pfam PF01872 RibD C-terminal domain 2 188 7.1E-24 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 MIM_c22940 2522d2552fd4dd6044f0d7a701d5a1be 1022 SUPERFAMILY SSF82693 136 312 9.42E-15 T 12-10-2018 MIM_c22940 2522d2552fd4dd6044f0d7a701d5a1be 1022 Gene3D G3DSA:3.30.70.1430 546 645 1.2E-281 T 12-10-2018 MIM_c22940 2522d2552fd4dd6044f0d7a701d5a1be 1022 Pfam PF00873 AcrB/AcrD/AcrF family 5 1003 1.5E-223 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c22940 2522d2552fd4dd6044f0d7a701d5a1be 1022 SUPERFAMILY SSF82693 544 644 8.37E-10 T 12-10-2018 MIM_c22940 2522d2552fd4dd6044f0d7a701d5a1be 1022 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 1.4E-51 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c22940 2522d2552fd4dd6044f0d7a701d5a1be 1022 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 1.4E-51 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c22940 2522d2552fd4dd6044f0d7a701d5a1be 1022 PRINTS PR00702 Acriflavin resistance protein family signature 531 548 1.4E-51 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c22940 2522d2552fd4dd6044f0d7a701d5a1be 1022 PRINTS PR00702 Acriflavin resistance protein family signature 436 459 1.4E-51 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c22940 2522d2552fd4dd6044f0d7a701d5a1be 1022 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.4E-51 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c22940 2522d2552fd4dd6044f0d7a701d5a1be 1022 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.4E-51 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c22940 2522d2552fd4dd6044f0d7a701d5a1be 1022 PRINTS PR00702 Acriflavin resistance protein family signature 355 376 1.4E-51 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c22940 2522d2552fd4dd6044f0d7a701d5a1be 1022 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 1.4E-51 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c22940 2522d2552fd4dd6044f0d7a701d5a1be 1022 Gene3D G3DSA:1.20.1640.10 500 1000 1.2E-281 T 12-10-2018 MIM_c22940 2522d2552fd4dd6044f0d7a701d5a1be 1022 Gene3D G3DSA:3.30.2090.10 694 784 1.2E-281 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c22940 2522d2552fd4dd6044f0d7a701d5a1be 1022 SUPERFAMILY SSF82866 783 1004 3.01E-44 T 12-10-2018 MIM_c22940 2522d2552fd4dd6044f0d7a701d5a1be 1022 Gene3D G3DSA:3.30.70.1320 134 324 1.2E-281 T 12-10-2018 MIM_c22940 2522d2552fd4dd6044f0d7a701d5a1be 1022 Gene3D G3DSA:3.30.70.1440 646 841 1.2E-281 T 12-10-2018 MIM_c22940 2522d2552fd4dd6044f0d7a701d5a1be 1022 Gene3D G3DSA:3.30.70.1430 40 792 1.2E-281 T 12-10-2018 MIM_c22940 2522d2552fd4dd6044f0d7a701d5a1be 1022 Gene3D G3DSA:1.20.1640.10 10 499 1.2E-281 T 12-10-2018 MIM_c22940 2522d2552fd4dd6044f0d7a701d5a1be 1022 SUPERFAMILY SSF82693 40 132 1.75E-20 T 12-10-2018 MIM_c22940 2522d2552fd4dd6044f0d7a701d5a1be 1022 SUPERFAMILY SSF82866 292 488 6.41E-45 T 12-10-2018 MIM_c22940 2522d2552fd4dd6044f0d7a701d5a1be 1022 Gene3D G3DSA:3.30.2090.10 178 268 1.2E-281 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c22940 2522d2552fd4dd6044f0d7a701d5a1be 1022 SUPERFAMILY SSF82714 695 782 5.75E-8 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c22940 2522d2552fd4dd6044f0d7a701d5a1be 1022 SUPERFAMILY SSF82714 182 264 1.31E-11 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c00300 1959c1d3c984d4c6e844b97b59576255 335 Gene3D G3DSA:3.40.190.150 42 326 4.4E-105 T 12-10-2018 MIM_c00300 1959c1d3c984d4c6e844b97b59576255 335 Gene3D G3DSA:3.40.190.10 138 261 4.4E-105 T 12-10-2018 MIM_c00300 1959c1d3c984d4c6e844b97b59576255 335 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 60 332 2.8E-82 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c00300 1959c1d3c984d4c6e844b97b59576255 335 SUPERFAMILY SSF53850 128 300 9.41E-10 T 12-10-2018 MIM_c00300 1959c1d3c984d4c6e844b97b59576255 335 PIRSF PIRSF017082 4 335 4.5E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c32190 3f0142c02ab1d8e320956b567c296c47 786 Gene3D G3DSA:3.20.20.70 418 772 1.3E-110 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c32190 3f0142c02ab1d8e320956b567c296c47 786 Gene3D G3DSA:3.50.50.60 3 349 2.8E-123 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c32190 3f0142c02ab1d8e320956b567c296c47 786 Gene3D G3DSA:3.30.9.20 40 256 2.8E-123 T 12-10-2018 MIM_c32190 3f0142c02ab1d8e320956b567c296c47 786 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 307 3.0E-10 T 12-10-2018 MIM_c32190 3f0142c02ab1d8e320956b567c296c47 786 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 3.0E-10 T 12-10-2018 MIM_c32190 3f0142c02ab1d8e320956b567c296c47 786 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 131 146 3.0E-10 T 12-10-2018 MIM_c32190 3f0142c02ab1d8e320956b567c296c47 786 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 276 291 3.0E-10 T 12-10-2018 MIM_c32190 3f0142c02ab1d8e320956b567c296c47 786 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 419 748 2.1E-64 T 12-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 MIM_c32190 3f0142c02ab1d8e320956b567c296c47 786 SUPERFAMILY SSF51905 1 357 9.99E-39 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c32190 3f0142c02ab1d8e320956b567c296c47 786 SUPERFAMILY SSF51395 416 772 4.71E-111 T 12-10-2018 MIM_c11570 81b6b07852723d28756d34400f4e3a93 373 SUPERFAMILY SSF57938 133 209 3.01E-22 T 12-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily MIM_c11570 81b6b07852723d28756d34400f4e3a93 373 Pfam PF00226 DnaJ domain 5 67 2.3E-27 T 12-10-2018 IPR001623 DnaJ domain MIM_c11570 81b6b07852723d28756d34400f4e3a93 373 SUPERFAMILY SSF49493 114 255 4.71E-18 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MIM_c11570 81b6b07852723d28756d34400f4e3a93 373 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 12-10-2018 IPR018253 DnaJ domain, conserved site MIM_c11570 81b6b07852723d28756d34400f4e3a93 373 Gene3D G3DSA:2.10.230.10 144 210 1.7E-21 T 12-10-2018 MIM_c11570 81b6b07852723d28756d34400f4e3a93 373 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 348 9.8E-135 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 MIM_c11570 81b6b07852723d28756d34400f4e3a93 373 SUPERFAMILY SSF49493 258 343 1.57E-22 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MIM_c11570 81b6b07852723d28756d34400f4e3a93 373 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 371 41.649 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 MIM_c11570 81b6b07852723d28756d34400f4e3a93 373 Pfam PF00684 DnaJ central domain 146 206 4.4E-14 T 12-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 MIM_c11570 81b6b07852723d28756d34400f4e3a93 373 Pfam PF01556 DnaJ C terminal domain 120 332 2.4E-41 T 12-10-2018 IPR002939 Chaperone DnaJ, C-terminal MIM_c11570 81b6b07852723d28756d34400f4e3a93 373 PRINTS PR00625 DnaJ domain signature 62 81 2.4E-32 T 12-10-2018 IPR001623 DnaJ domain MIM_c11570 81b6b07852723d28756d34400f4e3a93 373 PRINTS PR00625 DnaJ domain signature 42 62 2.4E-32 T 12-10-2018 IPR001623 DnaJ domain MIM_c11570 81b6b07852723d28756d34400f4e3a93 373 PRINTS PR00625 DnaJ domain signature 7 25 2.4E-32 T 12-10-2018 IPR001623 DnaJ domain MIM_c11570 81b6b07852723d28756d34400f4e3a93 373 PRINTS PR00625 DnaJ domain signature 25 40 2.4E-32 T 12-10-2018 IPR001623 DnaJ domain MIM_c11570 81b6b07852723d28756d34400f4e3a93 373 Gene3D G3DSA:2.60.260.20 255 361 4.3E-28 T 12-10-2018 MIM_c11570 81b6b07852723d28756d34400f4e3a93 373 SUPERFAMILY SSF46565 1 111 2.62E-37 T 12-10-2018 IPR036869 Chaperone J-domain superfamily MIM_c11570 81b6b07852723d28756d34400f4e3a93 373 SMART SM00271 4 62 8.8E-31 T 12-10-2018 IPR001623 DnaJ domain MIM_c11570 81b6b07852723d28756d34400f4e3a93 373 Gene3D G3DSA:1.10.287.110 1 110 8.6E-38 T 12-10-2018 IPR036869 Chaperone J-domain superfamily MIM_c15290 8166b0220ce52ae09163d55ea38c1d88 678 SUPERFAMILY SSF56935 33 678 1.31E-129 T 12-10-2018 MIM_c15290 8166b0220ce52ae09163d55ea38c1d88 678 Gene3D G3DSA:2.40.170.20 167 678 1.3E-134 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MIM_c15290 8166b0220ce52ae09163d55ea38c1d88 678 Gene3D G3DSA:2.170.130.10 28 161 1.4E-39 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MIM_c15290 8166b0220ce52ae09163d55ea38c1d88 678 Pfam PF00593 TonB dependent receptor 271 677 2.6E-60 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MIM_c15290 8166b0220ce52ae09163d55ea38c1d88 678 Pfam PF07715 TonB-dependent Receptor Plug Domain 46 156 1.8E-27 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain MIM_c07840 372fe84fe54e927dee955291306a98ac 613 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c07840 372fe84fe54e927dee955291306a98ac 613 Gene3D G3DSA:1.20.1560.10 4 341 1.9E-52 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MIM_c07840 372fe84fe54e927dee955291306a98ac 613 Pfam PF00005 ABC transporter 373 520 1.1E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c07840 372fe84fe54e927dee955291306a98ac 613 SMART SM00382 380 566 8.1E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c07840 372fe84fe54e927dee955291306a98ac 613 SUPERFAMILY SSF52540 344 591 1.68E-87 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c07840 372fe84fe54e927dee955291306a98ac 613 Gene3D G3DSA:3.40.50.300 345 602 1.5E-88 T 12-10-2018 MIM_c07840 372fe84fe54e927dee955291306a98ac 613 SUPERFAMILY SSF90123 21 330 1.7E-46 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MIM_c07840 372fe84fe54e927dee955291306a98ac 613 Pfam PF00664 ABC transporter transmembrane region 33 306 2.8E-20 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MIM_c09740 b420c17d34c45261b999749ede8bd7bd 510 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 14 500 2.4E-109 T 12-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MIM_c09740 b420c17d34c45261b999749ede8bd7bd 510 SUPERFAMILY SSF53623 129 361 2.35E-45 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MIM_c09740 b420c17d34c45261b999749ede8bd7bd 510 Gene3D G3DSA:3.40.1190.10 110 363 8.5E-51 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MIM_c09740 b420c17d34c45261b999749ede8bd7bd 510 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 13 502 31.274 T 12-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MIM_c09740 b420c17d34c45261b999749ede8bd7bd 510 Pfam PF08245 Mur ligase middle domain 135 343 1.2E-28 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MIM_c09740 b420c17d34c45261b999749ede8bd7bd 510 SUPERFAMILY SSF53244 367 502 2.88E-40 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MIM_c09740 b420c17d34c45261b999749ede8bd7bd 510 Gene3D G3DSA:3.90.190.20 369 501 5.1E-44 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MIM_c09740 b420c17d34c45261b999749ede8bd7bd 510 SUPERFAMILY SSF51984 13 99 1.53E-10 T 12-10-2018 MIM_c09740 b420c17d34c45261b999749ede8bd7bd 510 Gene3D G3DSA:3.40.50.720 12 108 3.6E-16 T 12-10-2018 MIM_c02190 320de94ed9ce677829395f1c06d664d7 311 Pfam PF01497 Periplasmic binding protein 52 281 6.1E-28 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain MIM_c02190 320de94ed9ce677829395f1c06d664d7 311 SUPERFAMILY SSF53807 31 293 1.14E-65 T 12-10-2018 MIM_c02190 320de94ed9ce677829395f1c06d664d7 311 Gene3D G3DSA:3.40.50.1980 42 296 5.2E-90 T 12-10-2018 MIM_c02190 320de94ed9ce677829395f1c06d664d7 311 Gene3D G3DSA:3.40.50.12260 178 282 5.2E-90 T 12-10-2018 MIM_c40620 412b45248a34de561f6710c79a9e0293 1416 SMART SM00663 235 514 3.8E-172 T 12-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c40620 412b45248a34de561f6710c79a9e0293 1416 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 11 1376 18.851 T 12-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c40620 412b45248a34de561f6710c79a9e0293 1416 SUPERFAMILY SSF64484 16 1363 0.0 T 12-10-2018 MIM_c40620 412b45248a34de561f6710c79a9e0293 1416 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 19 1365 0.0 T 12-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c40620 412b45248a34de561f6710c79a9e0293 1416 Pfam PF05000 RNA polymerase Rpb1, domain 4 674 763 4.9E-18 T 12-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c40620 412b45248a34de561f6710c79a9e0293 1416 Gene3D G3DSA:2.40.50.100 948 1023 5.8E-26 T 12-10-2018 MIM_c40620 412b45248a34de561f6710c79a9e0293 1416 Pfam PF04998 RNA polymerase Rpb1, domain 5 766 1315 8.7E-77 T 12-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c40620 412b45248a34de561f6710c79a9e0293 1416 Pfam PF00623 RNA polymerase Rpb1, domain 2 404 485 2.4E-26 T 12-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c40620 412b45248a34de561f6710c79a9e0293 1416 Pfam PF00623 RNA polymerase Rpb1, domain 2 344 396 2.2E-8 T 12-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c40620 412b45248a34de561f6710c79a9e0293 1416 Gene3D G3DSA:1.10.132.30 638 790 4.8E-64 T 12-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c40620 412b45248a34de561f6710c79a9e0293 1416 Gene3D G3DSA:2.40.50.100 1024 1126 8.9E-29 T 12-10-2018 MIM_c40620 412b45248a34de561f6710c79a9e0293 1416 Pfam PF04997 RNA polymerase Rpb1, domain 1 15 342 8.1E-87 T 12-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c40620 412b45248a34de561f6710c79a9e0293 1416 Pfam PF04983 RNA polymerase Rpb1, domain 3 489 644 6.3E-23 T 12-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c40620 412b45248a34de561f6710c79a9e0293 1416 Gene3D G3DSA:2.40.50.100 1151 1214 1.4E-66 T 12-10-2018 MIM_c40620 412b45248a34de561f6710c79a9e0293 1416 Gene3D G3DSA:1.10.1790.20 1135 1313 1.4E-66 T 12-10-2018 MIM_c40620 412b45248a34de561f6710c79a9e0293 1416 Gene3D G3DSA:1.10.40.90 374 416 9.9E-20 T 12-10-2018 MIM_c40620 412b45248a34de561f6710c79a9e0293 1416 Gene3D G3DSA:1.10.150.390 1315 1377 9.7E-29 T 12-10-2018 MIM_c40620 412b45248a34de561f6710c79a9e0293 1416 Gene3D G3DSA:1.10.274.100 490 637 1.7E-32 T 12-10-2018 MIM_c25580 2f57e90aaa7066dc4f38f1f42ab44391 274 Gene3D G3DSA:1.20.144.10 121 218 3.3E-21 T 12-10-2018 MIM_c25580 2f57e90aaa7066dc4f38f1f42ab44391 274 SUPERFAMILY SSF48317 6 207 2.88E-37 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily MIM_c25580 2f57e90aaa7066dc4f38f1f42ab44391 274 SMART SM00014 93 205 1.8E-13 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MIM_c25580 2f57e90aaa7066dc4f38f1f42ab44391 274 Pfam PF01569 PAP2 superfamily 95 205 6.5E-18 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MIM_c24570 e8e40bf011051d8ced00127d7adaaecd 204 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 33 166 1.6E-44 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24570 e8e40bf011051d8ced00127d7adaaecd 204 SUPERFAMILY SSF143243 8 186 6.41E-55 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24570 e8e40bf011051d8ced00127d7adaaecd 204 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 92 153 8.0E-24 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24570 e8e40bf011051d8ced00127d7adaaecd 204 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 32 164 1.8E-40 T 12-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24570 e8e40bf011051d8ced00127d7adaaecd 204 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 126 147 - T 12-10-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24570 e8e40bf011051d8ced00127d7adaaecd 204 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 7 173 34.39 T 12-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24570 e8e40bf011051d8ced00127d7adaaecd 204 Gene3D G3DSA:3.30.460.80 1 145 1.7E-44 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c31660 47ad8240d7f26e691295ff9a4cf903d7 232 Gene3D G3DSA:3.30.70.100 120 227 7.7E-6 T 12-10-2018 MIM_c31660 47ad8240d7f26e691295ff9a4cf903d7 232 SUPERFAMILY SSF54909 124 218 7.24E-10 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel MIM_c38440 1af6084d7a7ee7dd2ea40011f53bc838 241 SUPERFAMILY SSF52172 6 134 1.02E-38 T 12-10-2018 IPR011006 CheY-like superfamily MIM_c38440 1af6084d7a7ee7dd2ea40011f53bc838 241 Pfam PF00072 Response regulator receiver domain 14 123 9.6E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c38440 1af6084d7a7ee7dd2ea40011f53bc838 241 SUPERFAMILY SSF46894 142 234 1.98E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MIM_c38440 1af6084d7a7ee7dd2ea40011f53bc838 241 Gene3D G3DSA:1.10.10.10 138 240 1.9E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c38440 1af6084d7a7ee7dd2ea40011f53bc838 241 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 233 4.5E-18 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MIM_c38440 1af6084d7a7ee7dd2ea40011f53bc838 241 SMART SM00862 157 233 6.0E-18 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MIM_c38440 1af6084d7a7ee7dd2ea40011f53bc838 241 SMART SM00448 12 122 9.6E-37 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c38440 1af6084d7a7ee7dd2ea40011f53bc838 241 Gene3D G3DSA:3.40.50.2300 1 137 1.4E-34 T 12-10-2018 MIM_c13490 e05b06e70be9f284d48d72668209e375 704 Gene3D G3DSA:3.40.50.300 493 692 3.0E-35 T 12-10-2018 MIM_c13490 e05b06e70be9f284d48d72668209e375 704 SMART SM00491 534 660 2.1E-34 T 12-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 MIM_c13490 e05b06e70be9f284d48d72668209e375 704 Gene3D G3DSA:3.40.50.300 35 297 5.2E-46 T 12-10-2018 MIM_c13490 e05b06e70be9f284d48d72668209e375 704 SUPERFAMILY SSF52540 201 646 2.55E-9 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c13490 e05b06e70be9f284d48d72668209e375 704 Pfam PF13307 Helicase C-terminal domain 510 673 1.2E-32 T 12-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 MIM_c13490 e05b06e70be9f284d48d72668209e375 704 SUPERFAMILY SSF52540 13 646 1.63E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c13490 e05b06e70be9f284d48d72668209e375 704 SMART SM00487 33 296 0.0048 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MIM_c34320 75bf6e420c7e5729931e2ec803adc70e 339 SMART SM00382 28 211 7.6E-20 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c34320 75bf6e420c7e5729931e2ec803adc70e 339 SUPERFAMILY SSF52540 4 240 1.21E-86 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c34320 75bf6e420c7e5729931e2ec803adc70e 339 Pfam PF00005 ABC transporter 20 161 8.4E-37 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c34320 75bf6e420c7e5729931e2ec803adc70e 339 SUPERFAMILY SSF50331 254 338 3.74E-6 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MIM_c34320 75bf6e420c7e5729931e2ec803adc70e 339 Gene3D G3DSA:3.40.50.300 2 238 5.6E-80 T 12-10-2018 MIM_c34320 75bf6e420c7e5729931e2ec803adc70e 339 Pfam PF08402 TOBE domain 257 331 9.5E-7 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 MIM_c34320 75bf6e420c7e5729931e2ec803adc70e 339 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c05780 41b6c1c9bdc409c1415457eda1ad8b5d 212 SUPERFAMILY SSF47616 84 209 1.13E-19 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MIM_c05780 41b6c1c9bdc409c1415457eda1ad8b5d 212 Gene3D G3DSA:1.20.1050.10 86 198 8.1E-60 T 12-10-2018 MIM_c05780 41b6c1c9bdc409c1415457eda1ad8b5d 212 SUPERFAMILY SSF52833 3 86 3.34E-13 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c05780 41b6c1c9bdc409c1415457eda1ad8b5d 212 Gene3D G3DSA:3.40.30.10 7 205 8.1E-60 T 12-10-2018 MIM_c05780 41b6c1c9bdc409c1415457eda1ad8b5d 212 Pfam PF02798 Glutathione S-transferase, N-terminal domain 6 73 3.2E-6 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MIM_c05780 41b6c1c9bdc409c1415457eda1ad8b5d 212 Pfam PF00043 Glutathione S-transferase, C-terminal domain 126 199 1.1E-5 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal MIM_c32780 a9cc4e2dcd2de34b57ac5b8ccec7c815 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 117 136 3.7E-17 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MIM_c32780 a9cc4e2dcd2de34b57ac5b8ccec7c815 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 28 38 3.7E-17 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MIM_c32780 a9cc4e2dcd2de34b57ac5b8ccec7c815 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 142 151 3.7E-17 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MIM_c32780 a9cc4e2dcd2de34b57ac5b8ccec7c815 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 193 201 3.7E-17 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MIM_c32780 a9cc4e2dcd2de34b57ac5b8ccec7c815 322 Gene3D G3DSA:3.40.50.80 108 225 5.0E-26 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MIM_c32780 a9cc4e2dcd2de34b57ac5b8ccec7c815 322 Gene3D G3DSA:3.10.20.30 227 322 3.2E-22 T 12-10-2018 IPR012675 Beta-grasp domain superfamily MIM_c32780 a9cc4e2dcd2de34b57ac5b8ccec7c815 322 SUPERFAMILY SSF54292 216 321 1.44E-25 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MIM_c32780 a9cc4e2dcd2de34b57ac5b8ccec7c815 322 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 244 312 5.0E-8 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MIM_c32780 a9cc4e2dcd2de34b57ac5b8ccec7c815 322 Pfam PF00175 Oxidoreductase NAD-binding domain 118 206 6.8E-6 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MIM_c32780 a9cc4e2dcd2de34b57ac5b8ccec7c815 322 Gene3D G3DSA:2.40.30.10 1 105 4.7E-20 T 12-10-2018 MIM_c32780 a9cc4e2dcd2de34b57ac5b8ccec7c815 322 SUPERFAMILY SSF52343 110 225 9.43E-28 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MIM_c32780 a9cc4e2dcd2de34b57ac5b8ccec7c815 322 SUPERFAMILY SSF63380 2 104 5.91E-18 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MIM_c07430 3af5a717301754db93d9f4e57fd77e7f 591 Pfam PF13180 PDZ domain 494 573 3.8E-10 T 12-10-2018 IPR001478 PDZ domain GO:0005515 MIM_c07430 3af5a717301754db93d9f4e57fd77e7f 591 SMART SM00228 494 564 6.0E-5 T 12-10-2018 IPR001478 PDZ domain GO:0005515 MIM_c07430 3af5a717301754db93d9f4e57fd77e7f 591 SUPERFAMILY SSF55486 247 468 4.39E-9 T 12-10-2018 MIM_c07430 3af5a717301754db93d9f4e57fd77e7f 591 Pfam PF05299 M61 glycyl aminopeptidase 284 400 4.1E-47 T 12-10-2018 IPR007963 Peptidase M61, catalytic domain MIM_c07430 3af5a717301754db93d9f4e57fd77e7f 591 Gene3D G3DSA:1.10.390.60 182 470 1.5E-103 T 12-10-2018 MIM_c07430 3af5a717301754db93d9f4e57fd77e7f 591 Gene3D G3DSA:2.30.42.10 496 591 1.4E-18 T 12-10-2018 MIM_c07430 3af5a717301754db93d9f4e57fd77e7f 591 Gene3D G3DSA:2.60.40.3650 3 180 4.7E-65 T 12-10-2018 MIM_c07430 3af5a717301754db93d9f4e57fd77e7f 591 SUPERFAMILY SSF50156 509 574 1.84E-11 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 MIM_c07430 3af5a717301754db93d9f4e57fd77e7f 591 PIRSF PIRSF016493 1 591 3.5E-212 T 12-10-2018 IPR024191 Peptidase M61 MIM_c03040 d36e6171a136ddfc16db69ef6d824187 169 SUPERFAMILY SSF82199 14 152 1.57E-38 T 12-10-2018 MIM_c03040 d36e6171a136ddfc16db69ef6d824187 169 SMART SM00317 11 132 2.5E-26 T 12-10-2018 IPR001214 SET domain GO:0005515 MIM_c03040 d36e6171a136ddfc16db69ef6d824187 169 Pfam PF00856 SET domain 23 126 1.9E-18 T 12-10-2018 IPR001214 SET domain GO:0005515 MIM_c03040 d36e6171a136ddfc16db69ef6d824187 169 Gene3D G3DSA:2.170.270.10 6 169 4.5E-40 T 12-10-2018 MIM_c36950 e859ea15cf5e543c5b50e94a918dd081 1258 Pfam PF00809 Pterin binding enzyme 372 610 4.3E-57 T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MIM_c36950 e859ea15cf5e543c5b50e94a918dd081 1258 Gene3D G3DSA:3.40.50.280 774 929 1.3E-52 T 12-10-2018 MIM_c36950 e859ea15cf5e543c5b50e94a918dd081 1258 SUPERFAMILY SSF51717 368 635 7.2E-86 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MIM_c36950 e859ea15cf5e543c5b50e94a918dd081 1258 Gene3D G3DSA:1.10.1240.10 670 761 6.9E-38 T 12-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MIM_c36950 e859ea15cf5e543c5b50e94a918dd081 1258 PIRSF PIRSF000381 14 1230 0.0 T 12-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MIM_c36950 e859ea15cf5e543c5b50e94a918dd081 1258 Gene3D G3DSA:1.10.288.10 970 1128 1.1E-132 T 12-10-2018 MIM_c36950 e859ea15cf5e543c5b50e94a918dd081 1258 SUPERFAMILY SSF82282 20 411 2.22E-115 T 12-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 MIM_c36950 e859ea15cf5e543c5b50e94a918dd081 1258 Pfam PF02310 B12 binding domain 779 873 6.1E-18 T 12-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MIM_c36950 e859ea15cf5e543c5b50e94a918dd081 1258 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 971 1242 1.1E-116 T 12-10-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MIM_c36950 e859ea15cf5e543c5b50e94a918dd081 1258 SMART SM01018 677 764 3.9E-41 T 12-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MIM_c36950 e859ea15cf5e543c5b50e94a918dd081 1258 Gene3D G3DSA:3.10.196.10 941 1257 1.1E-132 T 12-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MIM_c36950 e859ea15cf5e543c5b50e94a918dd081 1258 Pfam PF02574 Homocysteine S-methyltransferase 29 337 2.3E-79 T 12-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 MIM_c36950 e859ea15cf5e543c5b50e94a918dd081 1258 TIGRFAM TIGR02082 metH: methionine synthase 26 1227 0.0 T 12-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MIM_c36950 e859ea15cf5e543c5b50e94a918dd081 1258 Gene3D G3DSA:3.20.20.330 16 351 4.2E-123 T 12-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 MIM_c36950 e859ea15cf5e543c5b50e94a918dd081 1258 SUPERFAMILY SSF52242 773 928 8.63E-42 T 12-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 MIM_c36950 e859ea15cf5e543c5b50e94a918dd081 1258 Gene3D G3DSA:3.20.20.20 352 665 5.0E-124 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MIM_c36950 e859ea15cf5e543c5b50e94a918dd081 1258 SUPERFAMILY SSF56507 935 1257 6.15E-121 T 12-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MIM_c36950 e859ea15cf5e543c5b50e94a918dd081 1258 SUPERFAMILY SSF47644 672 763 1.83E-26 T 12-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MIM_c36950 e859ea15cf5e543c5b50e94a918dd081 1258 Pfam PF02607 B12 binding domain 679 756 4.8E-25 T 12-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MIM_c17730 fe571a0917cc127da99c7208ec1a4f87 551 Pfam PF01494 FAD binding domain 9 369 9.8E-68 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 MIM_c17730 fe571a0917cc127da99c7208ec1a4f87 551 Gene3D G3DSA:3.40.30.120 424 551 3.0E-22 T 12-10-2018 MIM_c17730 fe571a0917cc127da99c7208ec1a4f87 551 Gene3D G3DSA:3.30.9.50 77 303 3.0E-97 T 12-10-2018 MIM_c17730 fe571a0917cc127da99c7208ec1a4f87 551 SUPERFAMILY SSF51905 9 381 2.87E-52 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c17730 fe571a0917cc127da99c7208ec1a4f87 551 Gene3D G3DSA:3.50.50.60 10 366 3.0E-97 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c17730 fe571a0917cc127da99c7208ec1a4f87 551 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 339 357 5.0E-39 T 12-10-2018 MIM_c17730 fe571a0917cc127da99c7208ec1a4f87 551 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 321 337 5.0E-39 T 12-10-2018 MIM_c17730 fe571a0917cc127da99c7208ec1a4f87 551 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 179 194 5.0E-39 T 12-10-2018 MIM_c17730 fe571a0917cc127da99c7208ec1a4f87 551 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 11 33 5.0E-39 T 12-10-2018 MIM_c17730 fe571a0917cc127da99c7208ec1a4f87 551 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 357 373 5.0E-39 T 12-10-2018 MIM_c17730 fe571a0917cc127da99c7208ec1a4f87 551 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 306 321 5.0E-39 T 12-10-2018 MIM_c06920 5b15a4c03717d52b635e347cd93b21da 378 Gene3D G3DSA:3.40.50.2000 22 374 2.4E-55 T 12-10-2018 MIM_c06920 5b15a4c03717d52b635e347cd93b21da 378 SUPERFAMILY SSF53756 19 377 2.83E-69 T 12-10-2018 MIM_c06920 5b15a4c03717d52b635e347cd93b21da 378 Pfam PF13439 Glycosyltransferase Family 4 22 178 3.3E-12 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MIM_c06920 5b15a4c03717d52b635e347cd93b21da 378 Pfam PF00534 Glycosyl transferases group 1 200 357 5.5E-29 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 MIM_c06920 5b15a4c03717d52b635e347cd93b21da 378 Gene3D G3DSA:3.40.50.2000 177 358 2.4E-55 T 12-10-2018 MIM_c02720 afc85b983d014ff6f4ec49c33d8a870a 388 Gene3D G3DSA:2.40.110.10 122 237 1.9E-32 T 12-10-2018 MIM_c02720 afc85b983d014ff6f4ec49c33d8a870a 388 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 340 359 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MIM_c02720 afc85b983d014ff6f4ec49c33d8a870a 388 PIRSF PIRSF016578 4 96 0.0042 T 12-10-2018 MIM_c02720 afc85b983d014ff6f4ec49c33d8a870a 388 PIRSF PIRSF016578 242 385 4.8E-11 T 12-10-2018 MIM_c02720 afc85b983d014ff6f4ec49c33d8a870a 388 PIRSF PIRSF016578 137 201 2.2 T 12-10-2018 MIM_c02720 afc85b983d014ff6f4ec49c33d8a870a 388 Gene3D G3DSA:1.20.140.10 238 382 7.5E-43 T 12-10-2018 MIM_c02720 afc85b983d014ff6f4ec49c33d8a870a 388 SUPERFAMILY SSF56645 1 232 3.93E-62 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c02720 afc85b983d014ff6f4ec49c33d8a870a 388 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 118 3.2E-24 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c02720 afc85b983d014ff6f4ec49c33d8a870a 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 220 1.6E-21 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MIM_c02720 afc85b983d014ff6f4ec49c33d8a870a 388 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 365 5.2E-39 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MIM_c02720 afc85b983d014ff6f4ec49c33d8a870a 388 SUPERFAMILY SSF47203 231 386 4.83E-49 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c02720 afc85b983d014ff6f4ec49c33d8a870a 388 Gene3D G3DSA:1.10.540.10 1 119 2.9E-30 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c15130 f2b1ff1b14bb7e44d7b4163a3d121c58 225 SUPERFAMILY SSF100950 4 152 1.12E-37 T 12-10-2018 IPR037171 NagB/RpiA transferase-like MIM_c15130 f2b1ff1b14bb7e44d7b4163a3d121c58 225 SUPERFAMILY SSF75445 133 204 7.19E-18 T 12-10-2018 MIM_c15130 f2b1ff1b14bb7e44d7b4163a3d121c58 225 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 8 220 3.1E-59 T 12-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 MIM_c15130 f2b1ff1b14bb7e44d7b4163a3d121c58 225 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 4 223 30.163 T 12-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 MIM_c15130 f2b1ff1b14bb7e44d7b4163a3d121c58 225 Gene3D G3DSA:3.40.50.1360 8 219 6.2E-68 T 12-10-2018 MIM_c15130 f2b1ff1b14bb7e44d7b4163a3d121c58 225 Gene3D G3DSA:3.30.70.260 131 202 6.2E-68 T 12-10-2018 MIM_c15130 f2b1ff1b14bb7e44d7b4163a3d121c58 225 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 54 219 3.8E-51 T 12-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 MIM_c31200 7e79aaf07efd5f07aa99a8b6f2f9ffee 157 Pfam PF01799 [2Fe-2S] binding domain 72 149 2.3E-23 T 12-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 MIM_c31200 7e79aaf07efd5f07aa99a8b6f2f9ffee 157 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MIM_c31200 7e79aaf07efd5f07aa99a8b6f2f9ffee 157 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 61 3.3E-8 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MIM_c31200 7e79aaf07efd5f07aa99a8b6f2f9ffee 157 Gene3D G3DSA:3.10.20.30 1 75 3.1E-27 T 12-10-2018 IPR012675 Beta-grasp domain superfamily MIM_c31200 7e79aaf07efd5f07aa99a8b6f2f9ffee 157 Gene3D G3DSA:1.10.150.120 79 157 7.3E-23 T 12-10-2018 MIM_c31200 7e79aaf07efd5f07aa99a8b6f2f9ffee 157 SUPERFAMILY SSF54292 3 76 8.52E-26 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MIM_c31200 7e79aaf07efd5f07aa99a8b6f2f9ffee 157 SUPERFAMILY SSF47741 84 155 2.22E-25 T 12-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily MIM_c23270 9ea42d9c04862f71f622a1660a348603 315 Gene3D G3DSA:3.40.190.10 174 276 7.4E-11 T 12-10-2018 MIM_c23270 9ea42d9c04862f71f622a1660a348603 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 18 74 1.4E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c23270 9ea42d9c04862f71f622a1660a348603 315 Gene3D G3DSA:3.40.190.10 105 286 7.4E-11 T 12-10-2018 MIM_c23270 9ea42d9c04862f71f622a1660a348603 315 SUPERFAMILY SSF46785 12 117 3.2E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c23270 9ea42d9c04862f71f622a1660a348603 315 Pfam PF03466 LysR substrate binding domain 102 288 4.1E-21 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c23270 9ea42d9c04862f71f622a1660a348603 315 SUPERFAMILY SSF53850 100 302 1.09E-22 T 12-10-2018 MIM_c23270 9ea42d9c04862f71f622a1660a348603 315 Gene3D G3DSA:1.10.10.10 16 103 8.6E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c03910 1e3ae3e259bfd40303394c290c909dca 129 Pfam PF01479 S4 domain 5 50 2.7E-11 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c03910 1e3ae3e259bfd40303394c290c909dca 129 SUPERFAMILY SSF55174 2 99 7.07E-27 T 12-10-2018 MIM_c03910 1e3ae3e259bfd40303394c290c909dca 129 Gene3D G3DSA:3.10.290.10 1 102 5.1E-35 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MIM_c03910 1e3ae3e259bfd40303394c290c909dca 129 SMART SM00363 4 65 4.2E-6 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c03910 1e3ae3e259bfd40303394c290c909dca 129 PIRSF PIRSF016821 1 128 1.4E-44 T 12-10-2018 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 MIM_c35460 9800e1930fe8d3edf57316674bbb7165 333 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 242 328 2.3E-25 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c35460 9800e1930fe8d3edf57316674bbb7165 333 SUPERFAMILY SSF52540 11 264 6.25E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c35460 9800e1930fe8d3edf57316674bbb7165 333 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c35460 9800e1930fe8d3edf57316674bbb7165 333 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 244 309 5.7E-19 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c35460 9800e1930fe8d3edf57316674bbb7165 333 Pfam PF00005 ABC transporter 41 192 8.0E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c35460 9800e1930fe8d3edf57316674bbb7165 333 Gene3D G3DSA:3.40.50.300 8 333 2.6E-94 T 12-10-2018 MIM_c35460 9800e1930fe8d3edf57316674bbb7165 333 SMART SM00382 50 242 1.4E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c27970 b493ef04915f6d9a4e26469921236e68 312 Pfam PF02355 Protein export membrane protein 107 291 2.0E-66 T 12-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial MIM_c27970 b493ef04915f6d9a4e26469921236e68 312 Gene3D G3DSA:1.20.1640.10 92 304 1.7E-14 T 12-10-2018 MIM_c27970 b493ef04915f6d9a4e26469921236e68 312 Pfam PF07549 SecD/SecF GG Motif 32 59 4.8E-9 T 12-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site MIM_c27970 b493ef04915f6d9a4e26469921236e68 312 PRINTS PR01755 Bacterial translocase SecF protein signature 151 165 2.1E-27 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MIM_c27970 b493ef04915f6d9a4e26469921236e68 312 PRINTS PR01755 Bacterial translocase SecF protein signature 37 52 2.1E-27 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MIM_c27970 b493ef04915f6d9a4e26469921236e68 312 PRINTS PR01755 Bacterial translocase SecF protein signature 199 217 2.1E-27 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MIM_c27970 b493ef04915f6d9a4e26469921236e68 312 PRINTS PR01755 Bacterial translocase SecF protein signature 231 246 2.1E-27 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MIM_c27970 b493ef04915f6d9a4e26469921236e68 312 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 38 283 1.6E-76 T 12-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 MIM_c27970 b493ef04915f6d9a4e26469921236e68 312 SUPERFAMILY SSF82866 75 294 1.09E-40 T 12-10-2018 MIM_c27970 b493ef04915f6d9a4e26469921236e68 312 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 10 294 27.929 T 12-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 MIM_c27970 b493ef04915f6d9a4e26469921236e68 312 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 98 280 2.4E-51 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MIM_c05690 23849229f29592c8a03e312cf981e967 255 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 42 57 - T 12-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 MIM_c05690 23849229f29592c8a03e312cf981e967 255 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 22 253 36.3 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MIM_c05690 23849229f29592c8a03e312cf981e967 255 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 31 253 2.3E-75 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MIM_c05690 23849229f29592c8a03e312cf981e967 255 Pfam PF01209 ubiE/COQ5 methyltransferase family 27 253 8.9E-87 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MIM_c05690 23849229f29592c8a03e312cf981e967 255 SUPERFAMILY SSF53335 23 251 2.79E-46 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c05690 23849229f29592c8a03e312cf981e967 255 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 162 176 - T 12-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 MIM_c05690 23849229f29592c8a03e312cf981e967 255 Gene3D G3DSA:3.40.50.150 37 254 1.6E-68 T 12-10-2018 MIM_c29550 0dc4218683a41f09970c21538cc61595 317 Gene3D G3DSA:3.40.50.1370 145 292 7.6E-88 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MIM_c29550 0dc4218683a41f09970c21538cc61595 317 PRINTS PR00101 Aspartate carbamoyltransferase signature 270 275 7.0E-28 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MIM_c29550 0dc4218683a41f09970c21538cc61595 317 PRINTS PR00101 Aspartate carbamoyltransferase signature 144 161 7.0E-28 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MIM_c29550 0dc4218683a41f09970c21538cc61595 317 PRINTS PR00101 Aspartate carbamoyltransferase signature 49 71 7.0E-28 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MIM_c29550 0dc4218683a41f09970c21538cc61595 317 PRINTS PR00101 Aspartate carbamoyltransferase signature 87 96 7.0E-28 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MIM_c29550 0dc4218683a41f09970c21538cc61595 317 PRINTS PR00101 Aspartate carbamoyltransferase signature 229 238 7.0E-28 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MIM_c29550 0dc4218683a41f09970c21538cc61595 317 PRINTS PR00101 Aspartate carbamoyltransferase signature 294 308 7.0E-28 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MIM_c29550 0dc4218683a41f09970c21538cc61595 317 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 59 78 1.5E-18 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MIM_c29550 0dc4218683a41f09970c21538cc61595 317 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 145 156 1.5E-18 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MIM_c29550 0dc4218683a41f09970c21538cc61595 317 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 266 275 1.5E-18 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MIM_c29550 0dc4218683a41f09970c21538cc61595 317 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 278 301 1.5E-18 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MIM_c29550 0dc4218683a41f09970c21538cc61595 317 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 59 66 - T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MIM_c29550 0dc4218683a41f09970c21538cc61595 317 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 14 312 3.2E-92 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MIM_c29550 0dc4218683a41f09970c21538cc61595 317 SUPERFAMILY SSF53671 13 314 1.96E-92 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MIM_c29550 0dc4218683a41f09970c21538cc61595 317 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 12 315 40.868 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MIM_c29550 0dc4218683a41f09970c21538cc61595 317 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 14 157 8.3E-37 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 MIM_c29550 0dc4218683a41f09970c21538cc61595 317 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 165 310 3.9E-24 T 12-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 MIM_c29550 0dc4218683a41f09970c21538cc61595 317 Gene3D G3DSA:3.40.50.1370 17 308 7.6E-88 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MIM_c10230 81a96f2c1a8428daed33fb2592c4a07b 337 PIRSF PIRSF006621 1 330 2.9E-99 T 12-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MIM_c10230 81a96f2c1a8428daed33fb2592c4a07b 337 Pfam PF01207 Dihydrouridine synthase (Dus) 14 322 4.0E-99 T 12-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MIM_c10230 81a96f2c1a8428daed33fb2592c4a07b 337 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 3 321 4.4E-117 T 12-10-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 MIM_c10230 81a96f2c1a8428daed33fb2592c4a07b 337 Gene3D G3DSA:3.20.20.70 7 251 1.5E-73 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c10230 81a96f2c1a8428daed33fb2592c4a07b 337 Hamap MF_02042 tRNA-dihydrouridine synthase B [dusB]. 1 324 49.178 T 12-10-2018 IPR032887 tRNA-dihydrouridine synthase B GO:0002943|GO:0017150 MIM_c10230 81a96f2c1a8428daed33fb2592c4a07b 337 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 94 112 - T 12-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 MIM_c10230 81a96f2c1a8428daed33fb2592c4a07b 337 SUPERFAMILY SSF51395 10 321 1.72E-86 T 12-10-2018 MIM_c10230 81a96f2c1a8428daed33fb2592c4a07b 337 Gene3D G3DSA:1.10.1200.80 256 329 4.5E-11 T 12-10-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 MIM_c22020 ed686228249667411e7099b211d6ca3b 218 Gene3D G3DSA:3.90.226.10 13 216 6.9E-81 T 12-10-2018 MIM_c22020 ed686228249667411e7099b211d6ca3b 218 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 133 146 - T 12-10-2018 IPR033135 ClpP, histidine active site MIM_c22020 ed686228249667411e7099b211d6ca3b 218 SUPERFAMILY SSF52096 32 214 1.74E-70 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c22020 ed686228249667411e7099b211d6ca3b 218 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 24 212 1.5E-103 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MIM_c22020 ed686228249667411e7099b211d6ca3b 218 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 24 214 43.469 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MIM_c22020 ed686228249667411e7099b211d6ca3b 218 Pfam PF00574 Clp protease 34 213 5.5E-85 T 12-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA MIM_c22020 ed686228249667411e7099b211d6ca3b 218 PRINTS PR00127 Clp protease catalytic subunit P signature 111 128 7.9E-49 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MIM_c22020 ed686228249667411e7099b211d6ca3b 218 PRINTS PR00127 Clp protease catalytic subunit P signature 80 100 7.9E-49 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MIM_c22020 ed686228249667411e7099b211d6ca3b 218 PRINTS PR00127 Clp protease catalytic subunit P signature 132 151 7.9E-49 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MIM_c22020 ed686228249667411e7099b211d6ca3b 218 PRINTS PR00127 Clp protease catalytic subunit P signature 189 208 7.9E-49 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MIM_c22020 ed686228249667411e7099b211d6ca3b 218 PRINTS PR00127 Clp protease catalytic subunit P signature 40 55 7.9E-49 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MIM_c07720 7cb6138241d7a00fea8a5520339c87d8 423 SUPERFAMILY SSF56672 1 236 2.76E-63 T 12-10-2018 MIM_c07720 7cb6138241d7a00fea8a5520339c87d8 423 Gene3D G3DSA:3.30.70.270 6 153 1.5E-38 T 12-10-2018 MIM_c07720 7cb6138241d7a00fea8a5520339c87d8 423 Pfam PF13438 Domain of unknown function (DUF4113) 370 420 7.2E-17 T 12-10-2018 IPR025188 Domain of unknown function DUF4113 MIM_c07720 7cb6138241d7a00fea8a5520339c87d8 423 Gene3D G3DSA:2.30.40.20 11 73 1.5E-38 T 12-10-2018 MIM_c07720 7cb6138241d7a00fea8a5520339c87d8 423 Pfam PF11799 impB/mucB/samB family C-terminal domain 240 352 3.3E-12 T 12-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MIM_c07720 7cb6138241d7a00fea8a5520339c87d8 423 Gene3D G3DSA:1.10.150.20 169 234 3.4E-9 T 12-10-2018 MIM_c07720 7cb6138241d7a00fea8a5520339c87d8 423 Pfam PF00817 impB/mucB/samB family 6 148 8.0E-33 T 12-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MIM_c31880 13e946762d8b06e22a8ba6e725115859 315 SUPERFAMILY SSF53474 25 308 1.96E-71 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c31880 13e946762d8b06e22a8ba6e725115859 315 Pfam PF07859 alpha/beta hydrolase fold 80 286 8.0E-73 T 12-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 MIM_c31880 13e946762d8b06e22a8ba6e725115859 315 Gene3D G3DSA:3.40.50.1820 1 314 1.6E-93 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c31880 13e946762d8b06e22a8ba6e725115859 315 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 80 96 - T 12-10-2018 IPR002168 Lipase, GDXG, putative histidine active site GO:0016787 Reactome: R-HSA-163560 MIM_c20750 55bd0fd05421f9e036163d1b6cb750d7 283 SMART SM00382 62 265 2.3E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c20750 55bd0fd05421f9e036163d1b6cb750d7 283 Pfam PF00005 ABC transporter 53 209 1.0E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c20750 55bd0fd05421f9e036163d1b6cb750d7 283 SUPERFAMILY SSF52540 36 278 2.66E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c20750 55bd0fd05421f9e036163d1b6cb750d7 283 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 257 278 4.4E-7 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal MIM_c20750 55bd0fd05421f9e036163d1b6cb750d7 283 Gene3D G3DSA:3.40.50.300 36 282 6.4E-60 T 12-10-2018 MIM_c32850 0c0ed828ddb37caddcf72e0db8f918e0 309 SUPERFAMILY SSF161098 70 297 5.36E-56 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c32850 0c0ed828ddb37caddcf72e0db8f918e0 309 Gene3D G3DSA:1.10.3720.10 65 307 8.9E-69 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c32850 0c0ed828ddb37caddcf72e0db8f918e0 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 302 8.9E-12 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c22300 bf218067a352c6f380ee51463bec4f9a 310 Pfam PF03466 LysR substrate binding domain 91 293 1.4E-45 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c22300 bf218067a352c6f380ee51463bec4f9a 310 SUPERFAMILY SSF46785 4 112 7.96E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c22300 bf218067a352c6f380ee51463bec4f9a 310 Gene3D G3DSA:3.40.190.290 91 293 9.8E-70 T 12-10-2018 MIM_c22300 bf218067a352c6f380ee51463bec4f9a 310 Gene3D G3DSA:1.10.10.10 3 88 5.5E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c22300 bf218067a352c6f380ee51463bec4f9a 310 SUPERFAMILY SSF53850 90 296 6.24E-49 T 12-10-2018 MIM_c22300 bf218067a352c6f380ee51463bec4f9a 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 3.1E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c29360 8d26079569c3cf53a60f10bbc3331854 471 PRINTS PR00987 Glutamyl-tRNA synthetase signature 14 26 7.3E-27 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MIM_c29360 8d26079569c3cf53a60f10bbc3331854 471 PRINTS PR00987 Glutamyl-tRNA synthetase signature 43 56 7.3E-27 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MIM_c29360 8d26079569c3cf53a60f10bbc3331854 471 PRINTS PR00987 Glutamyl-tRNA synthetase signature 28 39 7.3E-27 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MIM_c29360 8d26079569c3cf53a60f10bbc3331854 471 PRINTS PR00987 Glutamyl-tRNA synthetase signature 191 201 7.3E-27 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MIM_c29360 8d26079569c3cf53a60f10bbc3331854 471 PRINTS PR00987 Glutamyl-tRNA synthetase signature 207 215 7.3E-27 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MIM_c29360 8d26079569c3cf53a60f10bbc3331854 471 SUPERFAMILY SSF48163 311 470 9.02E-38 T 12-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MIM_c29360 8d26079569c3cf53a60f10bbc3331854 471 Gene3D G3DSA:1.10.10.350 384 471 4.9E-17 T 12-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MIM_c29360 8d26079569c3cf53a60f10bbc3331854 471 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 10 471 30.776 T 12-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MIM_c29360 8d26079569c3cf53a60f10bbc3331854 471 Gene3D G3DSA:3.40.50.620 9 326 8.5E-136 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c29360 8d26079569c3cf53a60f10bbc3331854 471 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 11 469 1.9E-171 T 12-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MIM_c29360 8d26079569c3cf53a60f10bbc3331854 471 SUPERFAMILY SSF52374 11 308 1.07E-110 T 12-10-2018 MIM_c29360 8d26079569c3cf53a60f10bbc3331854 471 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 11 317 3.3E-104 T 12-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 MIM_c29360 8d26079569c3cf53a60f10bbc3331854 471 Gene3D G3DSA:1.10.8.70 327 383 4.1E-5 T 12-10-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 MIM_c29360 8d26079569c3cf53a60f10bbc3331854 471 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 17 28 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c03030 2bf7ff3df11e406032714f94d2a236a9 167 Gene3D G3DSA:3.40.50.450 1 165 3.3E-53 T 12-10-2018 MIM_c03030 2bf7ff3df11e406032714f94d2a236a9 167 SUPERFAMILY SSF52309 1 160 2.29E-47 T 12-10-2018 MIM_c03030 2bf7ff3df11e406032714f94d2a236a9 167 Pfam PF05014 Nucleoside 2-deoxyribosyltransferase 4 140 2.0E-44 T 12-10-2018 IPR007710 Nucleoside 2-deoxyribosyltransferase Reactome: R-HSA-74259 MIM_c13570 72b8e10412b8091009b46352393f2729 374 Gene3D G3DSA:3.40.50.300 9 196 2.3E-39 T 12-10-2018 MIM_c13570 72b8e10412b8091009b46352393f2729 374 SUPERFAMILY SSF52540 10 185 4.23E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c13570 72b8e10412b8091009b46352393f2729 374 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 281 354 3.9E-7 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MIM_c13570 72b8e10412b8091009b46352393f2729 374 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 13 183 1.6E-33 T 12-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain MIM_c13570 72b8e10412b8091009b46352393f2729 374 SUPERFAMILY SSF90002 282 349 1.05E-7 T 12-10-2018 MIM_c13570 72b8e10412b8091009b46352393f2729 374 SMART SM00833 279 372 0.0064 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MIM_c21380 0b3b131ec0d739fc77d28054dbd2f4c8 451 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 419 429 - T 12-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site MIM_c21380 0b3b131ec0d739fc77d28054dbd2f4c8 451 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 363 397 - T 12-10-2018 IPR030390 RNA methyltransferase TrmA, active site MIM_c21380 0b3b131ec0d739fc77d28054dbd2f4c8 451 SUPERFAMILY SSF50249 4 59 4.91E-11 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c21380 0b3b131ec0d739fc77d28054dbd2f4c8 451 SUPERFAMILY SSF53335 62 435 5.09E-72 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c21380 0b3b131ec0d739fc77d28054dbd2f4c8 451 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 10 429 6.6E-92 T 12-10-2018 MIM_c21380 0b3b131ec0d739fc77d28054dbd2f4c8 451 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 4 437 65.613 T 12-10-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 MIM_c21380 0b3b131ec0d739fc77d28054dbd2f4c8 451 Gene3D G3DSA:3.40.1350.30 121 263 6.9E-101 T 12-10-2018 MIM_c21380 0b3b131ec0d739fc77d28054dbd2f4c8 451 Gene3D G3DSA:3.40.50.150 74 431 6.9E-101 T 12-10-2018 MIM_c21380 0b3b131ec0d739fc77d28054dbd2f4c8 451 Gene3D G3DSA:2.40.50.140 2 73 1.7E-21 T 12-10-2018 MIM_c21380 0b3b131ec0d739fc77d28054dbd2f4c8 451 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 260 431 1.9E-14 T 12-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 MIM_c36370 ac675dacb9f5d279d906af2bb6987b56 154 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 48 66 - T 12-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site MIM_c36370 ac675dacb9f5d279d906af2bb6987b56 154 SUPERFAMILY SSF46785 2 129 3.14E-35 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c36370 ac675dacb9f5d279d906af2bb6987b56 154 Gene3D G3DSA:1.10.10.10 1 137 3.4E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c36370 ac675dacb9f5d279d906af2bb6987b56 154 Pfam PF02082 Transcriptional regulator 1 81 1.1E-21 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type MIM_c36370 ac675dacb9f5d279d906af2bb6987b56 154 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 127 1.2E-34 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type MIM_c00420 6bae25977e852f52c9e804de9bf5ceec 393 Gene3D G3DSA:3.30.70.260 277 390 4.9E-12 T 12-10-2018 MIM_c00420 6bae25977e852f52c9e804de9bf5ceec 393 SUPERFAMILY SSF52540 47 283 1.1E-80 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c00420 6bae25977e852f52c9e804de9bf5ceec 393 Pfam PF09383 NIL domain 313 376 3.4E-13 T 12-10-2018 IPR018449 NIL domain MIM_c00420 6bae25977e852f52c9e804de9bf5ceec 393 SUPERFAMILY SSF55021 291 389 1.95E-11 T 12-10-2018 MIM_c00420 6bae25977e852f52c9e804de9bf5ceec 393 Gene3D G3DSA:3.40.50.300 45 276 3.1E-75 T 12-10-2018 MIM_c00420 6bae25977e852f52c9e804de9bf5ceec 393 SMART SM00382 74 262 1.3E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c00420 6bae25977e852f52c9e804de9bf5ceec 393 Pfam PF00005 ABC transporter 65 213 4.4E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c00420 6bae25977e852f52c9e804de9bf5ceec 393 ProSitePatterns PS00211 ABC transporters family signature. 185 199 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c00420 6bae25977e852f52c9e804de9bf5ceec 393 SMART SM00930 310 384 1.4E-9 T 12-10-2018 IPR018449 NIL domain MIM_c00200 6f976a0445cc8beb5bd60dd768f6a4be 138 Pfam PF07883 Cupin domain 52 124 3.4E-14 T 12-10-2018 IPR013096 Cupin 2, conserved barrel MIM_c00200 6f976a0445cc8beb5bd60dd768f6a4be 138 SUPERFAMILY SSF51182 21 130 3.7E-20 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c00200 6f976a0445cc8beb5bd60dd768f6a4be 138 Gene3D G3DSA:2.60.120.10 23 135 1.6E-17 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c33610 9cb72a8d76ded66a5d6e9ebe2100eb4d 229 Gene3D G3DSA:3.60.21.10 7 223 8.2E-45 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like MIM_c33610 9cb72a8d76ded66a5d6e9ebe2100eb4d 229 SUPERFAMILY SSF56300 12 210 1.24E-36 T 12-10-2018 MIM_c33610 9cb72a8d76ded66a5d6e9ebe2100eb4d 229 Pfam PF00149 Calcineurin-like phosphoesterase 21 191 5.9E-11 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MIM_c34930 8be567d2903dc21b82341b7f47da50ba 411 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 34 128 3.7E-12 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c34930 8be567d2903dc21b82341b7f47da50ba 411 PIRSF PIRSF016578 141 403 2.9E-18 T 12-10-2018 MIM_c34930 8be567d2903dc21b82341b7f47da50ba 411 PIRSF PIRSF016578 1 98 2.4E-12 T 12-10-2018 MIM_c34930 8be567d2903dc21b82341b7f47da50ba 411 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 143 222 3.3E-12 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MIM_c34930 8be567d2903dc21b82341b7f47da50ba 411 Gene3D G3DSA:1.20.140.10 234 409 1.4E-54 T 12-10-2018 MIM_c34930 8be567d2903dc21b82341b7f47da50ba 411 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 249 385 7.9E-17 T 12-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain MIM_c34930 8be567d2903dc21b82341b7f47da50ba 411 Gene3D G3DSA:2.40.110.10 131 233 9.0E-31 T 12-10-2018 MIM_c34930 8be567d2903dc21b82341b7f47da50ba 411 Gene3D G3DSA:1.10.540.10 27 129 8.2E-22 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c34930 8be567d2903dc21b82341b7f47da50ba 411 SUPERFAMILY SSF47203 245 402 2.58E-21 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c34930 8be567d2903dc21b82341b7f47da50ba 411 SUPERFAMILY SSF56645 32 230 2.75E-45 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c05720 75e38049110e5b1eb3933008af1474f0 332 SUPERFAMILY SSF53850 26 247 4.27E-37 T 12-10-2018 MIM_c05720 75e38049110e5b1eb3933008af1474f0 332 Gene3D G3DSA:3.40.190.10 18 131 2.4E-13 T 12-10-2018 MIM_c05720 75e38049110e5b1eb3933008af1474f0 332 Pfam PF13379 NMT1-like family 24 248 2.1E-22 T 12-10-2018 MIM_c05720 75e38049110e5b1eb3933008af1474f0 332 Gene3D G3DSA:3.40.190.10 132 321 2.0E-19 T 12-10-2018 MIM_c10490 544cc62014503ea33113889ad6283e31 706 Pfam PF01139 tRNA-splicing ligase RtcB 27 705 2.0E-133 T 12-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 MIM_c10490 544cc62014503ea33113889ad6283e31 706 Gene3D G3DSA:3.90.75.20 151 245 5.4E-7 T 12-10-2018 MIM_c10490 544cc62014503ea33113889ad6283e31 706 Pfam PF13392 HNH endonuclease 194 238 5.2E-14 T 12-10-2018 IPR003615 HNH nuclease MIM_c10490 544cc62014503ea33113889ad6283e31 706 SMART SM00305 338 385 3.7E-4 T 12-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MIM_c10490 544cc62014503ea33113889ad6283e31 706 SUPERFAMILY SSF51294 77 380 3.34E-23 T 12-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MIM_c10490 544cc62014503ea33113889ad6283e31 706 SUPERFAMILY SSF103365 379 705 3.92E-108 T 12-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 MIM_c10490 544cc62014503ea33113889ad6283e31 706 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 77 151 1.5E-8 T 12-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MIM_c10490 544cc62014503ea33113889ad6283e31 706 SMART SM00306 75 173 4.1E-4 T 12-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MIM_c10490 544cc62014503ea33113889ad6283e31 706 Pfam PF14890 Intein splicing domain 84 379 9.6E-21 T 12-10-2018 MIM_c10490 544cc62014503ea33113889ad6283e31 706 SUPERFAMILY SSF54060 175 244 2.35E-12 T 12-10-2018 MIM_c10490 544cc62014503ea33113889ad6283e31 706 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 319 340 - T 12-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 MIM_c10490 544cc62014503ea33113889ad6283e31 706 Gene3D G3DSA:3.90.1860.10 2 142 1.0E-16 T 12-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 MIM_c10490 544cc62014503ea33113889ad6283e31 706 Gene3D G3DSA:3.90.1860.10 366 705 9.1E-96 T 12-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 MIM_c10490 544cc62014503ea33113889ad6283e31 706 SUPERFAMILY SSF103365 10 77 4.58E-19 T 12-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 MIM_c10490 544cc62014503ea33113889ad6283e31 706 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 357 380 1.6E-7 T 12-10-2018 IPR030934 Intein C-terminal splicing region MIM_c24930 ed0a0000a8a5ccc503dd194fe63467f1 600 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 487 596 2.4E-22 T 12-10-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain MIM_c24930 ed0a0000a8a5ccc503dd194fe63467f1 600 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 34 154 2.4E-6 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c24930 ed0a0000a8a5ccc503dd194fe63467f1 600 SUPERFAMILY SSF56645 33 280 8.77E-51 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c24930 ed0a0000a8a5ccc503dd194fe63467f1 600 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 160 273 3.7E-18 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MIM_c24930 ed0a0000a8a5ccc503dd194fe63467f1 600 Gene3D G3DSA:1.10.540.10 19 157 2.6E-11 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c24930 ed0a0000a8a5ccc503dd194fe63467f1 600 Gene3D G3DSA:2.40.110.10 158 288 4.3E-23 T 12-10-2018 MIM_c24930 ed0a0000a8a5ccc503dd194fe63467f1 600 SUPERFAMILY SSF47203 297 470 1.16E-41 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c24930 ed0a0000a8a5ccc503dd194fe63467f1 600 Gene3D G3DSA:1.20.140.10 289 466 2.3E-39 T 12-10-2018 MIM_c24930 ed0a0000a8a5ccc503dd194fe63467f1 600 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 292 456 6.7E-19 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MIM_c24560 0be910d66e2c5081d6f0271e2cbc7b58 418 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 120 418 7.3E-123 T 12-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24560 0be910d66e2c5081d6f0271e2cbc7b58 418 SUPERFAMILY SSF56762 16 418 1.11E-136 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24560 0be910d66e2c5081d6f0271e2cbc7b58 418 Gene3D G3DSA:1.10.645.20 4 418 1.3E-172 T 12-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24560 0be910d66e2c5081d6f0271e2cbc7b58 418 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 43 54 - T 12-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24560 0be910d66e2c5081d6f0271e2cbc7b58 418 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 6 418 6.1E-186 T 12-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24560 0be910d66e2c5081d6f0271e2cbc7b58 418 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 1 418 50.124 T 12-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c02620 d113c7967b3fa73340629211cb181d8c 253 Pfam PF01061 ABC-2 type transporter 6 216 1.9E-35 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MIM_c02620 d113c7967b3fa73340629211cb181d8c 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 193 212 6.9E-13 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MIM_c02620 d113c7967b3fa73340629211cb181d8c 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 99 124 6.9E-13 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MIM_c02620 d113c7967b3fa73340629211cb181d8c 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 21 42 6.9E-13 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MIM_c02620 d113c7967b3fa73340629211cb181d8c 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 136 160 6.9E-13 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MIM_c02620 d113c7967b3fa73340629211cb181d8c 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 173 192 6.9E-13 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MIM_c02620 d113c7967b3fa73340629211cb181d8c 253 PIRSF PIRSF006648 12 250 2.6E-28 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MIM_c36800 29797e1230544828d7510a23906b91bc 404 SMART SM00922 157 267 4.1E-13 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MIM_c36800 29797e1230544828d7510a23906b91bc 404 Gene3D G3DSA:3.20.20.120 106 379 2.9E-95 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MIM_c36800 29797e1230544828d7510a23906b91bc 404 Gene3D G3DSA:3.30.390.10 1 105 1.7E-27 T 12-10-2018 IPR029017 Enolase-like, N-terminal MIM_c36800 29797e1230544828d7510a23906b91bc 404 SUPERFAMILY SSF54826 1 113 6.76E-29 T 12-10-2018 MIM_c36800 29797e1230544828d7510a23906b91bc 404 Pfam PF13378 Enolase C-terminal domain-like 166 387 8.9E-53 T 12-10-2018 IPR029065 Enolase C-terminal domain-like MIM_c36800 29797e1230544828d7510a23906b91bc 404 SUPERFAMILY SSF51604 97 391 4.72E-70 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MIM_c36800 29797e1230544828d7510a23906b91bc 404 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 11 109 2.6E-17 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain MIM_c23170 460352c290b600909e26698e2ae703de 372 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 9 372 38.801 T 12-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 MIM_c23170 460352c290b600909e26698e2ae703de 372 Gene3D G3DSA:3.40.50.620 1 218 6.0E-91 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c23170 460352c290b600909e26698e2ae703de 372 Gene3D G3DSA:2.40.30.10 293 372 3.2E-21 T 12-10-2018 MIM_c23170 460352c290b600909e26698e2ae703de 372 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 10 371 3.2E-129 T 12-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 MIM_c23170 460352c290b600909e26698e2ae703de 372 Pfam PF03054 tRNA methyl transferase 10 371 1.1E-128 T 12-10-2018 MIM_c23170 460352c290b600909e26698e2ae703de 372 SUPERFAMILY SSF52402 8 250 7.72E-57 T 12-10-2018 MIM_c23170 460352c290b600909e26698e2ae703de 372 Gene3D G3DSA:2.30.30.280 219 291 1.9E-26 T 12-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 MIM_c25630 48ebbbebea99e9b090366737cd6aa1df 695 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c25630 48ebbbebea99e9b090366737cd6aa1df 695 Pfam PF02687 FtsX-like permease family 602 688 4.1E-8 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MIM_c25630 48ebbbebea99e9b090366737cd6aa1df 695 Gene3D G3DSA:3.40.50.300 11 268 6.3E-65 T 12-10-2018 MIM_c25630 48ebbbebea99e9b090366737cd6aa1df 695 SMART SM00382 44 231 6.0E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c25630 48ebbbebea99e9b090366737cd6aa1df 695 Pfam PF00005 ABC transporter 35 183 4.3E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c25630 48ebbbebea99e9b090366737cd6aa1df 695 Pfam PF12704 MacB-like periplasmic core domain 321 539 5.3E-32 T 12-10-2018 IPR025857 MacB-like periplasmic core domain MIM_c25630 48ebbbebea99e9b090366737cd6aa1df 695 SUPERFAMILY SSF52540 13 236 7.26E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c26900 78b40495c6e58196b31a398e091ded1c 210 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 1 210 5.8E-84 T 12-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MIM_c26900 78b40495c6e58196b31a398e091ded1c 210 PIRSF PIRSF000190 1 210 9.4E-79 T 12-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MIM_c26900 78b40495c6e58196b31a398e091ded1c 210 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 34 118 1.7E-21 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MIM_c26900 78b40495c6e58196b31a398e091ded1c 210 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 179 192 - T 12-10-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MIM_c26900 78b40495c6e58196b31a398e091ded1c 210 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 169 210 1.3E-20 T 12-10-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MIM_c26900 78b40495c6e58196b31a398e091ded1c 210 Gene3D G3DSA:2.30.110.10 1 210 4.1E-80 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MIM_c26900 78b40495c6e58196b31a398e091ded1c 210 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 9 210 36.9 T 12-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MIM_c26900 78b40495c6e58196b31a398e091ded1c 210 SUPERFAMILY SSF50475 6 210 7.44E-59 T 12-10-2018 MIM_c17780 457164a4e8517d761dc9d0a7680c278f 132 Pfam PF06339 Ectoine synthase 1 126 2.5E-58 T 12-10-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108 MIM_c17780 457164a4e8517d761dc9d0a7680c278f 132 SUPERFAMILY SSF51182 1 126 1.54E-21 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c17780 457164a4e8517d761dc9d0a7680c278f 132 Gene3D G3DSA:2.60.120.10 1 116 2.2E-45 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c17780 457164a4e8517d761dc9d0a7680c278f 132 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 118 7.0E-56 T 12-10-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108 MIM_c17780 457164a4e8517d761dc9d0a7680c278f 132 Hamap MF_01255 L-ectoine synthase [ectC]. 1 128 40.806 T 12-10-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108 MIM_c40010 a91f2d0fd01a20a5782648dc00ee5995 262 Pfam PF03180 NLPA lipoprotein 27 262 9.7E-103 T 12-10-2018 IPR004872 Lipoprotein NlpA family MIM_c40010 a91f2d0fd01a20a5782648dc00ee5995 262 Gene3D G3DSA:3.40.190.10 108 212 2.3E-105 T 12-10-2018 MIM_c40010 a91f2d0fd01a20a5782648dc00ee5995 262 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 47 261 1.6E-73 T 12-10-2018 IPR004872 Lipoprotein NlpA family MIM_c40010 a91f2d0fd01a20a5782648dc00ee5995 262 SUPERFAMILY SSF53850 27 262 1.81E-88 T 12-10-2018 MIM_c40010 a91f2d0fd01a20a5782648dc00ee5995 262 PIRSF PIRSF002854 2 262 3.0E-108 T 12-10-2018 IPR004872 Lipoprotein NlpA family MIM_c40010 a91f2d0fd01a20a5782648dc00ee5995 262 Gene3D G3DSA:3.40.190.10 27 259 2.3E-105 T 12-10-2018 MIM_c14440 16e47011fa6e786d21b7d3e009fcf8c9 304 Gene3D G3DSA:3.40.190.10 133 244 4.7E-13 T 12-10-2018 MIM_c14440 16e47011fa6e786d21b7d3e009fcf8c9 304 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 45 274 5.2E-10 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c14440 16e47011fa6e786d21b7d3e009fcf8c9 304 SMART SM00062 44 289 1.5E-16 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c14440 16e47011fa6e786d21b7d3e009fcf8c9 304 SUPERFAMILY SSF53850 43 288 2.74E-20 T 12-10-2018 MIM_c14440 16e47011fa6e786d21b7d3e009fcf8c9 304 Gene3D G3DSA:3.40.190.10 43 273 4.7E-13 T 12-10-2018 MIM_c14440 16e47011fa6e786d21b7d3e009fcf8c9 304 TIGRFAM TIGR03871 ABC_peri_MoxJ_2: quinoprotein dehydrogenase-associated probable ABC transporter substrate-binding protein 45 290 9.4E-81 T 12-10-2018 IPR022448 Quinoprotein dehydrogenase-associated MIM_c34620 ed4e66505a36ff49423b1460a67306a0 320 SUPERFAMILY SSF53850 98 288 8.69E-25 T 12-10-2018 MIM_c34620 ed4e66505a36ff49423b1460a67306a0 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 2.9E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c34620 ed4e66505a36ff49423b1460a67306a0 320 Gene3D G3DSA:1.10.10.10 7 97 2.4E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c34620 ed4e66505a36ff49423b1460a67306a0 320 Gene3D G3DSA:3.40.190.10 99 282 2.0E-23 T 12-10-2018 MIM_c34620 ed4e66505a36ff49423b1460a67306a0 320 Pfam PF03466 LysR substrate binding domain 98 287 5.8E-23 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c34620 ed4e66505a36ff49423b1460a67306a0 320 SUPERFAMILY SSF46785 6 116 2.41E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c34620 ed4e66505a36ff49423b1460a67306a0 320 Gene3D G3DSA:3.40.190.10 169 273 2.0E-23 T 12-10-2018 MIM_c12330 244492f9df1651bbfe39e8b4b32bbf46 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 26 215 2.5E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c12330 244492f9df1651bbfe39e8b4b32bbf46 223 SUPERFAMILY SSF161098 10 207 2.09E-40 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c12330 244492f9df1651bbfe39e8b4b32bbf46 223 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 8 110 1.6E-22 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c12330 244492f9df1651bbfe39e8b4b32bbf46 223 TIGRFAM TIGR03004 ectoine_ehuC: ectoine/hydroxyectoine ABC transporter, permease protein EhuC 6 219 4.5E-82 T 12-10-2018 IPR014342 Ectoine/hydroxyectoine ABC transporter, permease protein EhuC MIM_c12330 244492f9df1651bbfe39e8b4b32bbf46 223 Gene3D G3DSA:1.10.3720.10 4 217 5.0E-47 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c27750 8a685d6b09ae0e65bf7622cefb522b72 280 Pfam PF00795 Carbon-nitrogen hydrolase 12 263 3.5E-41 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 MIM_c27750 8a685d6b09ae0e65bf7622cefb522b72 280 Gene3D G3DSA:3.60.110.10 1 278 1.5E-67 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MIM_c27750 8a685d6b09ae0e65bf7622cefb522b72 280 SUPERFAMILY SSF56317 8 272 1.7E-62 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MIM_c05670 af6bfc14d1235766bc615d7356a9bffe 446 SUPERFAMILY SSF55785 82 195 9.42E-5 T 12-10-2018 IPR035965 PAS domain superfamily MIM_c05670 af6bfc14d1235766bc615d7356a9bffe 446 Gene3D G3DSA:1.10.287.130 196 271 1.6E-21 T 12-10-2018 MIM_c05670 af6bfc14d1235766bc615d7356a9bffe 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 406 1.0E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c05670 af6bfc14d1235766bc615d7356a9bffe 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 381 1.0E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c05670 af6bfc14d1235766bc615d7356a9bffe 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 425 1.0E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c05670 af6bfc14d1235766bc615d7356a9bffe 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 367 1.0E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c05670 af6bfc14d1235766bc615d7356a9bffe 446 Pfam PF11808 Domain of unknown function (DUF3329) 8 85 6.8E-8 T 12-10-2018 IPR021766 Phosphate regulon sensor protein PhoR GO:0000155|GO:0000160|GO:0004721 MIM_c05670 af6bfc14d1235766bc615d7356a9bffe 446 SUPERFAMILY SSF55874 262 426 1.09E-38 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c05670 af6bfc14d1235766bc615d7356a9bffe 446 SMART SM00387 315 428 1.3E-35 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c05670 af6bfc14d1235766bc615d7356a9bffe 446 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 93 424 2.2E-113 T 12-10-2018 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 MIM_c05670 af6bfc14d1235766bc615d7356a9bffe 446 SMART SM00388 203 272 9.2E-21 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MIM_c05670 af6bfc14d1235766bc615d7356a9bffe 446 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 319 427 3.1E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c05670 af6bfc14d1235766bc615d7356a9bffe 446 Gene3D G3DSA:3.30.565.10 272 437 8.7E-39 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c05670 af6bfc14d1235766bc615d7356a9bffe 446 SUPERFAMILY SSF47384 189 272 3.34E-19 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MIM_c05670 af6bfc14d1235766bc615d7356a9bffe 446 Pfam PF00512 His Kinase A (phospho-acceptor) domain 204 271 6.7E-21 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MIM_c33620 065136f97edd5054d3733baa6e400c43 317 Gene3D G3DSA:1.10.490.140 65 163 1.8E-5 T 12-10-2018 MIM_c33620 065136f97edd5054d3733baa6e400c43 317 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 110 222 6.8E-6 T 12-10-2018 IPR003776 YcaO-like domain MIM_c18830 8a955bdcb55f312259f98794797de17e 654 Gene3D G3DSA:1.10.4030.30 246 382 2.4E-26 T 12-10-2018 MIM_c18830 8a955bdcb55f312259f98794797de17e 654 SUPERFAMILY SSF54534 263 371 7.2E-20 T 12-10-2018 MIM_c18830 8a955bdcb55f312259f98794797de17e 654 SUPERFAMILY SSF109998 42 240 1.02E-21 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily MIM_c18830 8a955bdcb55f312259f98794797de17e 654 Pfam PF13616 PPIC-type PPIASE domain 260 368 6.1E-17 T 12-10-2018 MIM_c18830 8a955bdcb55f312259f98794797de17e 654 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 308 329 - T 12-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 MIM_c18830 8a955bdcb55f312259f98794797de17e 654 Gene3D G3DSA:3.10.50.40 267 370 2.4E-26 T 12-10-2018 MIM_c18830 8a955bdcb55f312259f98794797de17e 654 Gene3D G3DSA:1.10.4030.30 43 174 1.8E-7 T 12-10-2018 MIM_c18830 8a955bdcb55f312259f98794797de17e 654 Pfam PF13624 SurA N-terminal domain 1 162 7.5E-41 T 12-10-2018 MIM_c08110 42da0955db5035cfcb1cf93ca2c9e90b 188 Gene3D G3DSA:3.40.50.300 9 173 3.0E-8 T 12-10-2018 MIM_c08110 42da0955db5035cfcb1cf93ca2c9e90b 188 Pfam PF13521 AAA domain 9 172 7.8E-40 T 12-10-2018 IPR038727 NadR/Ttd14, AAA domain MIM_c08110 42da0955db5035cfcb1cf93ca2c9e90b 188 SUPERFAMILY SSF52540 6 176 1.94E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c32750 d16de924b7459393ffe0c100c2aff1cb 546 ProSitePatterns PS00455 Putative AMP-binding domain signature. 169 180 - T 12-10-2018 IPR020845 AMP-binding, conserved site MIM_c32750 d16de924b7459393ffe0c100c2aff1cb 546 Pfam PF13193 AMP-binding enzyme C-terminal domain 433 514 7.6E-14 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MIM_c32750 d16de924b7459393ffe0c100c2aff1cb 546 Pfam PF00501 AMP-binding enzyme 13 424 2.9E-72 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MIM_c32750 d16de924b7459393ffe0c100c2aff1cb 546 Gene3D G3DSA:3.40.50.12780 1 417 1.5E-80 T 12-10-2018 MIM_c32750 d16de924b7459393ffe0c100c2aff1cb 546 Gene3D G3DSA:3.30.300.30 418 528 1.6E-24 T 12-10-2018 MIM_c32750 d16de924b7459393ffe0c100c2aff1cb 546 SUPERFAMILY SSF56801 5 529 3.92E-111 T 12-10-2018 MIM_c24300 2407b746166909b214eca88711cfdad4 1201 Pfam PF02463 RecF/RecN/SMC N terminal domain 29 1184 2.4E-64 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal MIM_c24300 2407b746166909b214eca88711cfdad4 1201 Gene3D G3DSA:3.40.50.300 898 1200 1.3E-46 T 12-10-2018 MIM_c24300 2407b746166909b214eca88711cfdad4 1201 Gene3D G3DSA:3.40.50.300 25 257 1.1E-50 T 12-10-2018 MIM_c24300 2407b746166909b214eca88711cfdad4 1201 SUPERFAMILY SSF57997 307 524 2.42E-8 T 12-10-2018 MIM_c24300 2407b746166909b214eca88711cfdad4 1201 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 28 1191 0.0 T 12-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 MIM_c24300 2407b746166909b214eca88711cfdad4 1201 SMART SM00968 544 651 8.8E-4 T 12-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 MIM_c24300 2407b746166909b214eca88711cfdad4 1201 Pfam PF06470 SMC proteins Flexible Hinge Domain 547 648 2.6E-6 T 12-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 MIM_c24300 2407b746166909b214eca88711cfdad4 1201 Hamap MF_01894 Chromosome partition protein Smc [smc]. 27 1193 22.211 T 12-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 MIM_c24300 2407b746166909b214eca88711cfdad4 1201 PIRSF PIRSF005719 26 1198 3.2E-256 T 12-10-2018 IPR024704 Structural maintenance of chromosomes protein MIM_c24300 2407b746166909b214eca88711cfdad4 1201 SUPERFAMILY SSF75553 512 699 1.96E-12 T 12-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 MIM_c24300 2407b746166909b214eca88711cfdad4 1201 SUPERFAMILY SSF52540 28 1194 3.23E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c22540 157a8d412cb21047f9a11a9365650d3c 212 SUPERFAMILY SSF53335 1 164 1.18E-26 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c22540 157a8d412cb21047f9a11a9365650d3c 212 Pfam PF13649 Methyltransferase domain 41 132 5.1E-13 T 12-10-2018 MIM_c22540 157a8d412cb21047f9a11a9365650d3c 212 Gene3D G3DSA:3.40.50.150 1 195 1.1E-40 T 12-10-2018 MIM_c34990 793912002d77c1c6477a9ccfb8b91313 532 SUPERFAMILY SSF53850 30 530 3.26E-133 T 12-10-2018 MIM_c34990 793912002d77c1c6477a9ccfb8b91313 532 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 76 442 1.9E-90 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain MIM_c34990 793912002d77c1c6477a9ccfb8b91313 532 Gene3D G3DSA:3.10.105.10 280 500 5.5E-130 T 12-10-2018 MIM_c34990 793912002d77c1c6477a9ccfb8b91313 532 Gene3D G3DSA:3.90.76.10 65 181 5.5E-130 T 12-10-2018 MIM_c34990 793912002d77c1c6477a9ccfb8b91313 532 PIRSF PIRSF002741 1 532 1.3E-136 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MIM_c34990 793912002d77c1c6477a9ccfb8b91313 532 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 82 104 - T 12-10-2018 IPR023765 Solute-binding protein family 5, conserved site MIM_c34990 793912002d77c1c6477a9ccfb8b91313 532 Gene3D G3DSA:3.40.190.10 44 514 5.5E-130 T 12-10-2018 MIM_c24920 dd61827cd4f0afe8949781c21f80ee4c 360 Gene3D G3DSA:3.20.20.70 2 351 1.2E-104 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c24920 dd61827cd4f0afe8949781c21f80ee4c 360 SUPERFAMILY SSF51412 15 352 2.59E-54 T 12-10-2018 MIM_c24920 dd61827cd4f0afe8949781c21f80ee4c 360 Pfam PF03060 Nitronate monooxygenase 10 349 5.9E-80 T 12-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 MIM_c24200 83eb1574e467f3794407f10795d81224 252 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c24200 83eb1574e467f3794407f10795d81224 252 Pfam PF00005 ABC transporter 21 170 1.9E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c24200 83eb1574e467f3794407f10795d81224 252 SUPERFAMILY SSF52540 4 240 7.21E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c24200 83eb1574e467f3794407f10795d81224 252 SMART SM00382 29 221 1.0E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c24200 83eb1574e467f3794407f10795d81224 252 Gene3D G3DSA:3.40.50.300 2 243 5.9E-57 T 12-10-2018 MIM_c26470 30a9568ce8bae48af4c1cf44e7f93917 256 SUPERFAMILY SSF46785 4 76 5.33E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c26470 30a9568ce8bae48af4c1cf44e7f93917 256 SUPERFAMILY SSF55781 75 247 1.24E-53 T 12-10-2018 MIM_c26470 30a9568ce8bae48af4c1cf44e7f93917 256 Pfam PF01614 Bacterial transcriptional regulator 121 243 3.5E-30 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal MIM_c26470 30a9568ce8bae48af4c1cf44e7f93917 256 Gene3D G3DSA:3.30.450.40 75 251 2.1E-58 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c26470 30a9568ce8bae48af4c1cf44e7f93917 256 SMART SM00346 2 93 2.6E-17 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c26470 30a9568ce8bae48af4c1cf44e7f93917 256 Gene3D G3DSA:1.10.10.10 3 74 1.3E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c26470 30a9568ce8bae48af4c1cf44e7f93917 256 Pfam PF09339 IclR helix-turn-helix domain 5 54 4.2E-9 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c12440 4d2c974582008818b079f2cf882cd6ec 288 Gene3D G3DSA:3.10.129.10 7 157 3.9E-42 T 12-10-2018 MIM_c12440 4d2c974582008818b079f2cf882cd6ec 288 SUPERFAMILY SSF54637 10 153 1.58E-40 T 12-10-2018 IPR029069 HotDog domain superfamily MIM_c12440 4d2c974582008818b079f2cf882cd6ec 288 Pfam PF01575 MaoC like domain 162 276 9.0E-27 T 12-10-2018 IPR002539 MaoC-like dehydratase domain MIM_c12440 4d2c974582008818b079f2cf882cd6ec 288 Gene3D G3DSA:3.10.129.10 160 288 3.7E-37 T 12-10-2018 MIM_c12440 4d2c974582008818b079f2cf882cd6ec 288 SUPERFAMILY SSF54637 163 279 3.84E-27 T 12-10-2018 IPR029069 HotDog domain superfamily MIM_c12440 4d2c974582008818b079f2cf882cd6ec 288 Pfam PF13452 N-terminal half of MaoC dehydratase 52 136 1.6E-10 T 12-10-2018 IPR039569 N-terminal of MaoC-like dehydratase Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-9033241|Reactome: R-HSA-9033500 MIM_c15220 51b25b7e74e24e25c547e6232ef2579a 119 Gene3D G3DSA:1.10.10.10 4 119 1.4E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c15220 51b25b7e74e24e25c547e6232ef2579a 119 Pfam PF01638 HxlR-like helix-turn-helix 20 105 4.0E-25 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type MIM_c15220 51b25b7e74e24e25c547e6232ef2579a 119 SMART SM00418 16 99 0.0063 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MIM_c15220 51b25b7e74e24e25c547e6232ef2579a 119 SUPERFAMILY SSF46785 10 105 2.51E-29 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c33060 b7e7393fe82f279805fc6790ebfdc5ec 391 Pfam PF07690 Major Facilitator Superfamily 8 230 3.1E-26 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c33060 b7e7393fe82f279805fc6790ebfdc5ec 391 SUPERFAMILY SSF103473 6 383 6.93E-51 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c33060 b7e7393fe82f279805fc6790ebfdc5ec 391 ProSitePatterns PS00216 Sugar transport proteins signature 1. 61 77 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MIM_c33060 b7e7393fe82f279805fc6790ebfdc5ec 391 Gene3D G3DSA:1.20.1250.20 3 382 2.0E-49 T 12-10-2018 MIM_c20510 020322fd753d040dd50bc20910c6985d 334 SUPERFAMILY SSF53850 115 296 4.35E-10 T 12-10-2018 MIM_c20510 020322fd753d040dd50bc20910c6985d 334 PIRSF PIRSF017082 1 333 1.3E-56 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c20510 020322fd753d040dd50bc20910c6985d 334 Gene3D G3DSA:3.40.190.150 37 325 6.1E-84 T 12-10-2018 MIM_c20510 020322fd753d040dd50bc20910c6985d 334 Gene3D G3DSA:3.40.190.10 133 256 6.1E-84 T 12-10-2018 MIM_c20510 020322fd753d040dd50bc20910c6985d 334 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 327 3.1E-60 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c25010 671f711b2f872b64add57f016b78dcc7 695 SUPERFAMILY SSF48179 478 580 1.19E-25 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c25010 671f711b2f872b64add57f016b78dcc7 695 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 299 474 6.6E-59 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MIM_c25010 671f711b2f872b64add57f016b78dcc7 695 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 95 115 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 MIM_c25010 671f711b2f872b64add57f016b78dcc7 695 Gene3D G3DSA:1.10.1040.50 482 694 6.0E-72 T 12-10-2018 MIM_c25010 671f711b2f872b64add57f016b78dcc7 695 SUPERFAMILY SSF48179 602 693 6.63E-20 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c25010 671f711b2f872b64add57f016b78dcc7 695 Gene3D G3DSA:3.90.226.10 3 294 1.8E-83 T 12-10-2018 MIM_c25010 671f711b2f872b64add57f016b78dcc7 695 SUPERFAMILY SSF52096 7 288 3.32E-65 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c25010 671f711b2f872b64add57f016b78dcc7 695 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 607 690 5.8E-5 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MIM_c25010 671f711b2f872b64add57f016b78dcc7 695 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 479 571 9.9E-25 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MIM_c25010 671f711b2f872b64add57f016b78dcc7 695 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 193 7.4E-38 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c25010 671f711b2f872b64add57f016b78dcc7 695 Gene3D G3DSA:3.40.50.720 295 481 5.8E-63 T 12-10-2018 MIM_c25010 671f711b2f872b64add57f016b78dcc7 695 SUPERFAMILY SSF51735 295 474 3.95E-54 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c13830 dcbd402b3965f047007c0120c4ec6d23 289 Gene3D G3DSA:3.20.20.60 1 288 2.3E-85 T 12-10-2018 MIM_c13830 dcbd402b3965f047007c0120c4ec6d23 289 SUPERFAMILY SSF51621 1 236 1.37E-56 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MIM_c13830 dcbd402b3965f047007c0120c4ec6d23 289 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 2 226 1.9E-38 T 12-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 MIM_c13830 dcbd402b3965f047007c0120c4ec6d23 289 PIRSF PIRSF015582 1 288 3.7E-74 T 12-10-2018 IPR011206 Citrate lyase beta subunit-like MIM_c37280 1df9356bab93e6ab265b49b1e3d3af1a 1124 SUPERFAMILY SSF82171 339 586 2.9E-18 T 12-10-2018 MIM_c37280 1df9356bab93e6ab265b49b1e3d3af1a 1124 Gene3D G3DSA:2.130.10.10 336 554 8.6E-9 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MIM_c37280 1df9356bab93e6ab265b49b1e3d3af1a 1124 Gene3D G3DSA:3.40.50.10140 1 145 3.3E-16 T 12-10-2018 IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily MIM_c37280 1df9356bab93e6ab265b49b1e3d3af1a 1124 SUPERFAMILY SSF50978 697 964 1.04E-24 T 12-10-2018 IPR036322 WD40-repeat-containing domain superfamily GO:0005515 MIM_c37280 1df9356bab93e6ab265b49b1e3d3af1a 1124 SUPERFAMILY SSF52200 3 128 2.88E-11 T 12-10-2018 IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily MIM_c37280 1df9356bab93e6ab265b49b1e3d3af1a 1124 Pfam PF13676 TIR domain 15 129 1.8E-8 T 12-10-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 MIM_c37280 1df9356bab93e6ab265b49b1e3d3af1a 1124 Gene3D G3DSA:2.130.10.10 718 859 3.2E-10 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MIM_c37280 1df9356bab93e6ab265b49b1e3d3af1a 1124 Gene3D G3DSA:2.130.10.10 860 990 2.0E-9 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MIM_c19280 a4b7a2be502de01076f6d3a791df4ed4 408 SUPERFAMILY SSF103473 7 394 9.55E-57 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c19280 a4b7a2be502de01076f6d3a791df4ed4 408 Gene3D G3DSA:1.20.1720.10 11 386 1.3E-86 T 12-10-2018 MIM_c19280 a4b7a2be502de01076f6d3a791df4ed4 408 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 9 378 1.4E-75 T 12-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 MIM_c19280 a4b7a2be502de01076f6d3a791df4ed4 408 Pfam PF07690 Major Facilitator Superfamily 15 354 7.0E-41 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c34370 ae33bdc1e72efe83f1879efac3ec5ffc 366 Pfam PF13784 Fic/DOC family N-terminal 26 108 9.3E-22 T 12-10-2018 IPR025758 Fic/DOC N-terminal MIM_c34370 ae33bdc1e72efe83f1879efac3ec5ffc 366 PIRSF PIRSF038925 1 360 3.2E-106 T 12-10-2018 IPR026287 Adenosine monophosphate-protein transferase MIM_c34370 ae33bdc1e72efe83f1879efac3ec5ffc 366 Gene3D G3DSA:1.10.3290.10 40 274 5.9E-34 T 12-10-2018 IPR036597 Fido-like domain superfamily MIM_c34370 ae33bdc1e72efe83f1879efac3ec5ffc 366 Pfam PF02661 Fic/DOC family 139 213 2.2E-16 T 12-10-2018 IPR003812 Fido domain MIM_c34370 ae33bdc1e72efe83f1879efac3ec5ffc 366 SUPERFAMILY SSF140931 95 280 9.42E-30 T 12-10-2018 IPR036597 Fido-like domain superfamily MIM_c12280 8a789f65c2834866da12e83a9b139b2d 301 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 10 296 62.646 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MIM_c12280 8a789f65c2834866da12e83a9b139b2d 301 Gene3D G3DSA:3.20.20.70 11 301 9.0E-104 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c12280 8a789f65c2834866da12e83a9b139b2d 301 SUPERFAMILY SSF51569 11 299 3.87E-98 T 12-10-2018 MIM_c12280 8a789f65c2834866da12e83a9b139b2d 301 SMART SM01130 10 298 1.2E-130 T 12-10-2018 IPR002220 DapA-like GO:0016829 MIM_c12280 8a789f65c2834866da12e83a9b139b2d 301 PIRSF PIRSF001365 8 301 7.1E-90 T 12-10-2018 IPR002220 DapA-like GO:0016829 MIM_c12280 8a789f65c2834866da12e83a9b139b2d 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 112 128 5.9E-34 T 12-10-2018 IPR002220 DapA-like GO:0016829 MIM_c12280 8a789f65c2834866da12e83a9b139b2d 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 137 154 5.9E-34 T 12-10-2018 IPR002220 DapA-like GO:0016829 MIM_c12280 8a789f65c2834866da12e83a9b139b2d 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 44 65 5.9E-34 T 12-10-2018 IPR002220 DapA-like GO:0016829 MIM_c12280 8a789f65c2834866da12e83a9b139b2d 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 80 98 5.9E-34 T 12-10-2018 IPR002220 DapA-like GO:0016829 MIM_c12280 8a789f65c2834866da12e83a9b139b2d 301 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 142 172 - T 12-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 MIM_c12280 8a789f65c2834866da12e83a9b139b2d 301 Pfam PF00701 Dihydrodipicolinate synthetase family 11 295 1.6E-95 T 12-10-2018 IPR002220 DapA-like GO:0016829 MIM_c12280 8a789f65c2834866da12e83a9b139b2d 301 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 14 296 2.2E-103 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MIM_c28320 5a2f4dcaecc5ba4f8a9341faa92de4dd 216 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 126 205 6.1E-31 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MIM_c28320 5a2f4dcaecc5ba4f8a9341faa92de4dd 216 SUPERFAMILY SSF53155 43 129 8.44E-13 T 12-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MIM_c28320 5a2f4dcaecc5ba4f8a9341faa92de4dd 216 Gene3D G3DSA:1.10.10.10 124 207 4.4E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c28320 5a2f4dcaecc5ba4f8a9341faa92de4dd 216 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 47 206 35.403 T 12-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 MIM_c28320 5a2f4dcaecc5ba4f8a9341faa92de4dd 216 SUPERFAMILY SSF46767 125 207 4.71E-30 T 12-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 MIM_c28320 5a2f4dcaecc5ba4f8a9341faa92de4dd 216 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 176 182 - T 12-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MIM_c28320 5a2f4dcaecc5ba4f8a9341faa92de4dd 216 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 43 121 1.2E-8 T 12-10-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MIM_c28320 5a2f4dcaecc5ba4f8a9341faa92de4dd 216 Gene3D G3DSA:3.30.160.70 43 122 4.4E-13 T 12-10-2018 MIM_c28320 5a2f4dcaecc5ba4f8a9341faa92de4dd 216 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 127 207 3.8E-31 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MIM_24p00210 6f74b7ffc0b497004a2f9dea804d9726 90 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 7 88 1.9E-27 T 12-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MIM_24p00210 6f74b7ffc0b497004a2f9dea804d9726 90 Gene3D G3DSA:3.30.2310.20 3 89 9.1E-34 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MIM_24p00210 6f74b7ffc0b497004a2f9dea804d9726 90 Pfam PF15738 Bacterial toxin of type II toxin-antitoxin system, YafQ 6 89 1.8E-34 T 12-10-2018 IPR004386 Toxin-antitoxin system, YafQ-like toxin MIM_24p00210 6f74b7ffc0b497004a2f9dea804d9726 90 PIRSF PIRSF006156 1 90 1.7E-27 T 12-10-2018 IPR004386 Toxin-antitoxin system, YafQ-like toxin MIM_24p00210 6f74b7ffc0b497004a2f9dea804d9726 90 TIGRFAM TIGR00053 TIGR00053: addiction module toxin component, YafQ family 7 88 2.4E-28 T 12-10-2018 IPR004386 Toxin-antitoxin system, YafQ-like toxin MIM_24p00210 6f74b7ffc0b497004a2f9dea804d9726 90 SUPERFAMILY SSF143011 5 88 6.67E-27 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MIM_c40080 b59a5433dea6ed50f3e0b950f611bddb 125 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 124 1.0E-69 T 12-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c40080 b59a5433dea6ed50f3e0b950f611bddb 125 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.037 T 12-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c40080 b59a5433dea6ed50f3e0b950f611bddb 125 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c40080 b59a5433dea6ed50f3e0b950f611bddb 125 PRINTS PR01034 Ribosomal protein S12 signature 58 77 8.1E-61 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c40080 b59a5433dea6ed50f3e0b950f611bddb 125 PRINTS PR01034 Ribosomal protein S12 signature 77 94 8.1E-61 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c40080 b59a5433dea6ed50f3e0b950f611bddb 125 PRINTS PR01034 Ribosomal protein S12 signature 110 122 8.1E-61 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c40080 b59a5433dea6ed50f3e0b950f611bddb 125 PRINTS PR01034 Ribosomal protein S12 signature 42 57 8.1E-61 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c40080 b59a5433dea6ed50f3e0b950f611bddb 125 PRINTS PR01034 Ribosomal protein S12 signature 27 42 8.1E-61 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c40080 b59a5433dea6ed50f3e0b950f611bddb 125 PRINTS PR01034 Ribosomal protein S12 signature 94 110 8.1E-61 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c40080 b59a5433dea6ed50f3e0b950f611bddb 125 Pfam PF00164 Ribosomal protein S12/S23 16 123 7.3E-43 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c40080 b59a5433dea6ed50f3e0b950f611bddb 125 Gene3D G3DSA:2.40.50.140 1 125 2.0E-63 T 12-10-2018 MIM_c40080 b59a5433dea6ed50f3e0b950f611bddb 125 PIRSF PIRSF002133 1 124 5.6E-55 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c40080 b59a5433dea6ed50f3e0b950f611bddb 125 SUPERFAMILY SSF50249 2 124 3.6E-52 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c18940 12b41279d5b59a41756aa65a7a879622 470 Gene3D G3DSA:3.30.590.10 106 458 5.1E-144 T 12-10-2018 MIM_c18940 12b41279d5b59a41756aa65a7a879622 470 SUPERFAMILY SSF54368 3 98 4.45E-33 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MIM_c18940 12b41279d5b59a41756aa65a7a879622 470 SMART SM01230 103 380 1.5E-145 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MIM_c18940 12b41279d5b59a41756aa65a7a879622 470 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 6 469 8.3E-195 T 12-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MIM_c18940 12b41279d5b59a41756aa65a7a879622 470 ProSitePatterns PS00180 Glutamine synthetase signature 1. 51 69 - T 12-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MIM_c18940 12b41279d5b59a41756aa65a7a879622 470 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 387 399 - T 12-10-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MIM_c18940 12b41279d5b59a41756aa65a7a879622 470 Gene3D G3DSA:3.10.20.70 3 105 6.0E-36 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MIM_c18940 12b41279d5b59a41756aa65a7a879622 470 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 15 96 1.4E-29 T 12-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MIM_c18940 12b41279d5b59a41756aa65a7a879622 470 SUPERFAMILY SSF55931 103 469 2.94E-135 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 MIM_c18940 12b41279d5b59a41756aa65a7a879622 470 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 260 275 - T 12-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MIM_c18940 12b41279d5b59a41756aa65a7a879622 470 Pfam PF00120 Glutamine synthetase, catalytic domain 104 467 3.1E-134 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MIM_c12730 63f5785565f5266cd42bf0820683b9d4 258 Gene3D G3DSA:3.30.450.40 92 254 1.7E-24 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c12730 63f5785565f5266cd42bf0820683b9d4 258 Gene3D G3DSA:1.10.10.10 2 84 5.0E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c12730 63f5785565f5266cd42bf0820683b9d4 258 SUPERFAMILY SSF55781 89 253 7.19E-25 T 12-10-2018 MIM_c12730 63f5785565f5266cd42bf0820683b9d4 258 Pfam PF01614 Bacterial transcriptional regulator 140 232 1.0E-7 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal MIM_c12730 63f5785565f5266cd42bf0820683b9d4 258 SUPERFAMILY SSF46785 18 88 5.45E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c12730 63f5785565f5266cd42bf0820683b9d4 258 SMART SM00346 16 106 6.9E-14 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c12730 63f5785565f5266cd42bf0820683b9d4 258 Pfam PF09339 IclR helix-turn-helix domain 18 68 6.3E-14 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c36260 e873bcaf80408850bfc984194224d8bf 232 Pfam PF01965 DJ-1/PfpI family 10 169 5.7E-26 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 MIM_c36260 e873bcaf80408850bfc984194224d8bf 232 SUPERFAMILY SSF52317 8 189 2.93E-43 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c36260 e873bcaf80408850bfc984194224d8bf 232 Gene3D G3DSA:3.40.50.880 3 229 2.2E-64 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c00240 6d7344721aa49299837ad3bfdc2542dd 291 SUPERFAMILY SSF161098 89 270 8.37E-30 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c00240 6d7344721aa49299837ad3bfdc2542dd 291 Gene3D G3DSA:1.10.3720.10 90 281 6.9E-24 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c00240 6d7344721aa49299837ad3bfdc2542dd 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 281 5.9E-24 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c14630 8ed1cc227f8ce3d78d3f5d5ad3a4c010 450 Gene3D G3DSA:3.40.50.12780 12 437 2.5E-53 T 12-10-2018 MIM_c14630 8ed1cc227f8ce3d78d3f5d5ad3a4c010 450 SUPERFAMILY SSF56801 6 436 1.31E-50 T 12-10-2018 MIM_c14630 8ed1cc227f8ce3d78d3f5d5ad3a4c010 450 Pfam PF00501 AMP-binding enzyme 38 435 2.8E-33 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MIM_c11320 9aeb8ff965db28bdde89babc5f38fedc 283 Gene3D G3DSA:3.40.50.1820 31 280 9.1E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c11320 9aeb8ff965db28bdde89babc5f38fedc 283 SUPERFAMILY SSF53474 36 277 1.46E-38 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c11320 9aeb8ff965db28bdde89babc5f38fedc 283 Pfam PF12697 Alpha/beta hydrolase family 52 273 4.5E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c31020 43e9f96ff76d8e3faa2b6353ba4aa1c4 476 Gene3D G3DSA:3.40.605.10 10 471 8.9E-160 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c31020 43e9f96ff76d8e3faa2b6353ba4aa1c4 476 SUPERFAMILY SSF53720 4 473 7.07E-155 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c31020 43e9f96ff76d8e3faa2b6353ba4aa1c4 476 Pfam PF00171 Aldehyde dehydrogenase family 14 472 1.2E-153 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c31020 43e9f96ff76d8e3faa2b6353ba4aa1c4 476 Gene3D G3DSA:3.40.309.10 254 443 8.9E-160 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MIM_c37810 f4575f1191efc29baf18d0b4f4b573a1 219 Gene3D G3DSA:3.40.50.300 1 219 3.6E-44 T 12-10-2018 MIM_c37810 f4575f1191efc29baf18d0b4f4b573a1 219 ProSitePatterns PS00211 ABC transporters family signature. 126 140 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c37810 f4575f1191efc29baf18d0b4f4b573a1 219 Pfam PF00005 ABC transporter 22 153 2.6E-16 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c37810 f4575f1191efc29baf18d0b4f4b573a1 219 SUPERFAMILY SSF52540 1 215 2.45E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c37810 f4575f1191efc29baf18d0b4f4b573a1 219 SMART SM00382 30 209 1.1E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c36660 593b5e1019d67c297ed78bf7943c71d2 270 SMART SM00079 39 260 2.9E-6 T 12-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 MIM_c36660 593b5e1019d67c297ed78bf7943c71d2 270 SMART SM00062 39 261 3.5E-60 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c36660 593b5e1019d67c297ed78bf7943c71d2 270 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 259 1.3E-60 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c36660 593b5e1019d67c297ed78bf7943c71d2 270 Gene3D G3DSA:3.40.190.10 42 258 2.5E-68 T 12-10-2018 MIM_c36660 593b5e1019d67c297ed78bf7943c71d2 270 Gene3D G3DSA:3.40.190.10 123 220 2.5E-68 T 12-10-2018 MIM_c36660 593b5e1019d67c297ed78bf7943c71d2 270 SUPERFAMILY SSF53850 13 259 1.44E-65 T 12-10-2018 MIM_c16870 7e9d3c04aa6aacb73d925e8670d20a3a 273 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 5 70 2.6E-25 T 12-10-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 MIM_c16870 7e9d3c04aa6aacb73d925e8670d20a3a 273 Gene3D G3DSA:2.160.10.10 88 258 1.2E-57 T 12-10-2018 MIM_c16870 7e9d3c04aa6aacb73d925e8670d20a3a 273 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 135 163 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MIM_c16870 7e9d3c04aa6aacb73d925e8670d20a3a 273 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 5 272 2.5E-142 T 12-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 MIM_c16870 7e9d3c04aa6aacb73d925e8670d20a3a 273 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 2 273 56.387 T 12-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 MIM_c16870 7e9d3c04aa6aacb73d925e8670d20a3a 273 SUPERFAMILY SSF51161 3 257 5.27E-75 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily MIM_c16870 7e9d3c04aa6aacb73d925e8670d20a3a 273 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 116 167 5.1E-4 T 12-10-2018 IPR001451 Hexapeptide repeat MIM_c16870 7e9d3c04aa6aacb73d925e8670d20a3a 273 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 176 210 2.0E-13 T 12-10-2018 IPR001451 Hexapeptide repeat MIM_c16870 7e9d3c04aa6aacb73d925e8670d20a3a 273 Gene3D G3DSA:1.10.166.10 1 71 1.4E-28 T 12-10-2018 IPR037133 Tetrahydrodipicolinate-N-succinyltransferase, N-terminal domain superfamily KEGG: 00300+2.3.1.117 MIM_c19930 1ff487bee8dafd3fba1c3dd09afaa8c3 308 Gene3D G3DSA:1.10.10.10 8 99 3.9E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c19930 1ff487bee8dafd3fba1c3dd09afaa8c3 308 Gene3D G3DSA:3.40.190.10 170 274 1.9E-49 T 12-10-2018 MIM_c19930 1ff487bee8dafd3fba1c3dd09afaa8c3 308 Gene3D G3DSA:3.40.190.10 100 294 1.9E-49 T 12-10-2018 MIM_c19930 1ff487bee8dafd3fba1c3dd09afaa8c3 308 SUPERFAMILY SSF46785 9 117 1.15E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c19930 1ff487bee8dafd3fba1c3dd09afaa8c3 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 4.7E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c19930 1ff487bee8dafd3fba1c3dd09afaa8c3 308 SUPERFAMILY SSF53850 94 301 4.04E-34 T 12-10-2018 MIM_c19930 1ff487bee8dafd3fba1c3dd09afaa8c3 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 8.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c19930 1ff487bee8dafd3fba1c3dd09afaa8c3 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 8.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c19930 1ff487bee8dafd3fba1c3dd09afaa8c3 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 8.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c19930 1ff487bee8dafd3fba1c3dd09afaa8c3 308 Pfam PF03466 LysR substrate binding domain 93 293 4.2E-35 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c02680 27eec24558a7070fcc5aec93ad8e0950 334 Gene3D G3DSA:3.40.190.100 120 249 3.3E-38 T 12-10-2018 MIM_c02680 27eec24558a7070fcc5aec93ad8e0950 334 Gene3D G3DSA:3.10.105.10 20 119 2.9E-7 T 12-10-2018 MIM_c02680 27eec24558a7070fcc5aec93ad8e0950 334 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 36 313 1.4E-62 T 12-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 MIM_c02680 27eec24558a7070fcc5aec93ad8e0950 334 SUPERFAMILY SSF53850 30 330 6.51E-81 T 12-10-2018 MIM_c10800 e7189d6088b9a331dbf7cff2757f3937 572 Gene3D G3DSA:3.40.50.300 41 258 3.2E-18 T 12-10-2018 MIM_c10800 e7189d6088b9a331dbf7cff2757f3937 572 Pfam PF03354 Phage Terminase 84 552 1.6E-72 T 12-10-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type MIM_c11380 6a7597da1f96fd24e0009747c4eef589 212 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 33 211 2.9E-78 T 12-10-2018 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 MIM_c11380 6a7597da1f96fd24e0009747c4eef589 212 Gene3D G3DSA:1.20.120.80 26 211 1.0E-53 T 12-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c11380 6a7597da1f96fd24e0009747c4eef589 212 SUPERFAMILY SSF81452 22 209 3.53E-56 T 12-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c11380 6a7597da1f96fd24e0009747c4eef589 212 Pfam PF00510 Cytochrome c oxidase subunit III 28 209 4.1E-15 T 12-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c25770 daae762a55e227e62b66c55b75ca98dd 409 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 174 184 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site MIM_c25770 daae762a55e227e62b66c55b75ca98dd 409 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 343 353 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site MIM_c25770 daae762a55e227e62b66c55b75ca98dd 409 SUPERFAMILY SSF52743 128 396 6.94E-71 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 MIM_c25770 daae762a55e227e62b66c55b75ca98dd 409 PRINTS PR00723 Subtilisin serine protease family (S8) signature 170 183 5.4E-22 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related MIM_c25770 daae762a55e227e62b66c55b75ca98dd 409 PRINTS PR00723 Subtilisin serine protease family (S8) signature 342 358 5.4E-22 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related MIM_c25770 daae762a55e227e62b66c55b75ca98dd 409 PRINTS PR00723 Subtilisin serine protease family (S8) signature 133 152 5.4E-22 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related MIM_c25770 daae762a55e227e62b66c55b75ca98dd 409 Gene3D G3DSA:3.40.50.200 89 401 8.3E-76 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 MIM_c25770 daae762a55e227e62b66c55b75ca98dd 409 Pfam PF00082 Subtilase family 133 391 4.2E-48 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MIM_c30550 b6778f0dc0a3079bc8568e58250b8495 556 SUPERFAMILY SSF52540 16 266 1.39E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c30550 b6778f0dc0a3079bc8568e58250b8495 556 SUPERFAMILY SSF52540 287 534 3.66E-72 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c30550 b6778f0dc0a3079bc8568e58250b8495 556 ProSitePatterns PS00211 ABC transporters family signature. 435 449 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c30550 b6778f0dc0a3079bc8568e58250b8495 556 Gene3D G3DSA:3.40.50.300 287 556 2.1E-85 T 12-10-2018 MIM_c30550 b6778f0dc0a3079bc8568e58250b8495 556 Gene3D G3DSA:3.40.50.300 14 286 6.3E-83 T 12-10-2018 MIM_c30550 b6778f0dc0a3079bc8568e58250b8495 556 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 514 539 0.0013 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c30550 b6778f0dc0a3079bc8568e58250b8495 556 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 247 279 5.4E-6 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c30550 b6778f0dc0a3079bc8568e58250b8495 556 Pfam PF00005 ABC transporter 36 195 2.8E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c30550 b6778f0dc0a3079bc8568e58250b8495 556 SMART SM00382 45 245 4.0E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c30550 b6778f0dc0a3079bc8568e58250b8495 556 SMART SM00382 321 512 8.7E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c30550 b6778f0dc0a3079bc8568e58250b8495 556 Pfam PF00005 ABC transporter 313 462 2.6E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c30550 b6778f0dc0a3079bc8568e58250b8495 556 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c17550 2284b6990a9672972f14fd0b5da25ab7 485 Pfam PF00171 Aldehyde dehydrogenase family 17 471 3.2E-173 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c17550 2284b6990a9672972f14fd0b5da25ab7 485 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 241 248 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MIM_c17550 2284b6990a9672972f14fd0b5da25ab7 485 Gene3D G3DSA:3.40.309.10 246 441 2.9E-177 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MIM_c17550 2284b6990a9672972f14fd0b5da25ab7 485 SUPERFAMILY SSF53720 3 477 2.75E-165 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c17550 2284b6990a9672972f14fd0b5da25ab7 485 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 269 280 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MIM_c17550 2284b6990a9672972f14fd0b5da25ab7 485 Gene3D G3DSA:3.40.605.10 7 469 2.9E-177 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c17550 2284b6990a9672972f14fd0b5da25ab7 485 TIGRFAM TIGR02299 HpaE: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 3 485 2.3E-239 T 12-10-2018 IPR011985 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase GO:0018480|GO:1901023 MIM_c16680 83f8288312f273b9e56c954a404e4fdc 351 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MIM_c16680 83f8288312f273b9e56c954a404e4fdc 351 TIGRFAM TIGR00033 aroC: chorismate synthase 10 349 6.7E-133 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MIM_c16680 83f8288312f273b9e56c954a404e4fdc 351 ProSitePatterns PS00789 Chorismate synthase signature 3. 319 335 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MIM_c16680 83f8288312f273b9e56c954a404e4fdc 351 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MIM_c16680 83f8288312f273b9e56c954a404e4fdc 351 Gene3D G3DSA:3.60.150.10 1 351 1.6E-143 T 12-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MIM_c16680 83f8288312f273b9e56c954a404e4fdc 351 Pfam PF01264 Chorismate synthase 10 345 6.4E-130 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MIM_c16680 83f8288312f273b9e56c954a404e4fdc 351 Hamap MF_00300 Chorismate synthase [aroC]. 10 349 35.042 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MIM_c16680 83f8288312f273b9e56c954a404e4fdc 351 SUPERFAMILY SSF103263 4 349 2.88E-140 T 12-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MIM_c16680 83f8288312f273b9e56c954a404e4fdc 351 PIRSF PIRSF001456 3 351 2.0E-129 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MIM_c13290 dc7b56ac1c353e8d1b749e7b9902c9d8 167 Gene3D G3DSA:1.10.10.10 3 160 4.9E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c13290 dc7b56ac1c353e8d1b749e7b9902c9d8 167 Pfam PF01047 MarR family 51 110 5.3E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c13290 dc7b56ac1c353e8d1b749e7b9902c9d8 167 SMART SM00347 44 145 7.4E-20 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c13290 dc7b56ac1c353e8d1b749e7b9902c9d8 167 ProSitePatterns PS01117 MarR-type HTH domain signature. 84 118 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MIM_c13290 dc7b56ac1c353e8d1b749e7b9902c9d8 167 SUPERFAMILY SSF46785 20 159 4.27E-30 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c13290 dc7b56ac1c353e8d1b749e7b9902c9d8 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 85 3.9E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c13290 dc7b56ac1c353e8d1b749e7b9902c9d8 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 135 155 3.9E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c13290 dc7b56ac1c353e8d1b749e7b9902c9d8 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 101 3.9E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c13290 dc7b56ac1c353e8d1b749e7b9902c9d8 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 105 121 3.9E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c39510 f8d395b5c354ac8b5165b5eb32b838b1 281 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 72 279 4.1E-69 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 MIM_c39510 f8d395b5c354ac8b5165b5eb32b838b1 281 SUPERFAMILY SSF56529 62 280 2.09E-79 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MIM_c39510 f8d395b5c354ac8b5165b5eb32b838b1 281 Gene3D G3DSA:3.90.850.10 67 281 3.7E-84 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MIM_c01010 76715eca814b9421d794e84e8d8021c6 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.5E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01010 76715eca814b9421d794e84e8d8021c6 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 1.5E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01010 76715eca814b9421d794e84e8d8021c6 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 1.5E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01010 76715eca814b9421d794e84e8d8021c6 265 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c01010 76715eca814b9421d794e84e8d8021c6 265 SUPERFAMILY SSF51735 6 262 9.21E-76 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c01010 76715eca814b9421d794e84e8d8021c6 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 2.9E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01010 76715eca814b9421d794e84e8d8021c6 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 2.9E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01010 76715eca814b9421d794e84e8d8021c6 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 2.9E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01010 76715eca814b9421d794e84e8d8021c6 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 2.9E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01010 76715eca814b9421d794e84e8d8021c6 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 2.9E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01010 76715eca814b9421d794e84e8d8021c6 265 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 261 3.0E-61 T 12-10-2018 MIM_c01010 76715eca814b9421d794e84e8d8021c6 265 Gene3D G3DSA:3.40.50.720 1 264 1.1E-80 T 12-10-2018 MIM_c29490 e3cb037224683d521281674444acbcec 282 SUPERFAMILY SSF53223 4 104 6.33E-26 T 12-10-2018 MIM_c29490 e3cb037224683d521281674444acbcec 282 Gene3D G3DSA:3.40.50.10860 7 261 2.4E-74 T 12-10-2018 MIM_c29490 e3cb037224683d521281674444acbcec 282 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 4 277 30.717 T 12-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 MIM_c29490 e3cb037224683d521281674444acbcec 282 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 6 278 7.7E-73 T 12-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 MIM_c29490 e3cb037224683d521281674444acbcec 282 Gene3D G3DSA:3.40.50.720 118 243 2.4E-74 T 12-10-2018 MIM_c29490 e3cb037224683d521281674444acbcec 282 SUPERFAMILY SSF51735 105 276 1.19E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c29490 e3cb037224683d521281674444acbcec 282 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 9 92 6.6E-20 T 12-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 MIM_c29490 e3cb037224683d521281674444acbcec 282 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 119 198 1.5E-11 T 12-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase MIM_c14560 3cfe1de1a1609021b50f4186e52ca0dd 285 Pfam PF00793 DAHP synthetase I family 9 273 6.1E-66 T 12-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MIM_c14560 3cfe1de1a1609021b50f4186e52ca0dd 285 SUPERFAMILY SSF51569 2 276 3.66E-101 T 12-10-2018 MIM_c14560 3cfe1de1a1609021b50f4186e52ca0dd 285 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 13 274 1.4E-122 T 12-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MIM_c14560 3cfe1de1a1609021b50f4186e52ca0dd 285 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 8 276 53.021 T 12-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MIM_c14560 3cfe1de1a1609021b50f4186e52ca0dd 285 Gene3D G3DSA:3.20.20.70 3 281 5.9E-101 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c20030 477aeed9ed5ec59719ff1427504760bf 191 Gene3D G3DSA:2.60.120.480 10 170 1.6E-15 T 12-10-2018 IPR024060 Ureidoglycolate lyase domain superfamily GO:0004848 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 MIM_c20030 477aeed9ed5ec59719ff1427504760bf 191 SUPERFAMILY SSF51182 11 157 1.82E-21 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c20030 477aeed9ed5ec59719ff1427504760bf 191 Pfam PF04115 Ureidoglycolate lyase 64 158 1.4E-11 T 12-10-2018 IPR007247 Ureidoglycolate lyase GO:0000256|GO:0050385 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 MIM_c17840 eb81a24eb50e76ce6652ae282ff4836d 946 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c17840 eb81a24eb50e76ce6652ae282ff4836d 946 TIGRFAM TIGR00422 valS: valine--tRNA ligase 11 928 0.0 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MIM_c17840 eb81a24eb50e76ce6652ae282ff4836d 946 Hamap MF_02004 Valine--tRNA ligase [valS]. 10 946 15.64 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MIM_c17840 eb81a24eb50e76ce6652ae282ff4836d 946 Gene3D G3DSA:3.90.740.10 253 347 4.0E-26 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MIM_c17840 eb81a24eb50e76ce6652ae282ff4836d 946 SUPERFAMILY SSF50677 205 359 3.4E-62 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MIM_c17840 eb81a24eb50e76ce6652ae282ff4836d 946 SUPERFAMILY SSF52374 10 642 1.42E-134 T 12-10-2018 MIM_c17840 eb81a24eb50e76ce6652ae282ff4836d 946 Pfam PF08264 Anticodon-binding domain of tRNA 674 827 1.8E-40 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 MIM_c17840 eb81a24eb50e76ce6652ae282ff4836d 946 SUPERFAMILY SSF46589 881 945 1.52E-16 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 MIM_c17840 eb81a24eb50e76ce6652ae282ff4836d 946 Gene3D G3DSA:3.90.740.10 214 252 1.5E-5 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MIM_c17840 eb81a24eb50e76ce6652ae282ff4836d 946 Gene3D G3DSA:1.10.730.10 583 821 1.7E-70 T 12-10-2018 MIM_c17840 eb81a24eb50e76ce6652ae282ff4836d 946 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 881 945 3.4E-18 T 12-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 MIM_c17840 eb81a24eb50e76ce6652ae282ff4836d 946 Gene3D G3DSA:3.40.50.620 348 582 2.6E-62 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c17840 eb81a24eb50e76ce6652ae282ff4836d 946 SUPERFAMILY SSF47323 643 896 3.74E-59 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c17840 eb81a24eb50e76ce6652ae282ff4836d 946 Gene3D G3DSA:1.10.287.380 874 945 9.7E-16 T 12-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 MIM_c17840 eb81a24eb50e76ce6652ae282ff4836d 946 Gene3D G3DSA:3.40.50.620 12 213 2.2E-59 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c17840 eb81a24eb50e76ce6652ae282ff4836d 946 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 23 632 1.0E-203 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c17840 eb81a24eb50e76ce6652ae282ff4836d 946 PRINTS PR00986 Valyl-tRNA synthetase signature 50 61 1.6E-34 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MIM_c17840 eb81a24eb50e76ce6652ae282ff4836d 946 PRINTS PR00986 Valyl-tRNA synthetase signature 507 525 1.6E-34 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MIM_c17840 eb81a24eb50e76ce6652ae282ff4836d 946 PRINTS PR00986 Valyl-tRNA synthetase signature 476 497 1.6E-34 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MIM_c17840 eb81a24eb50e76ce6652ae282ff4836d 946 PRINTS PR00986 Valyl-tRNA synthetase signature 247 264 1.6E-34 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MIM_c17840 eb81a24eb50e76ce6652ae282ff4836d 946 PRINTS PR00986 Valyl-tRNA synthetase signature 363 376 1.6E-34 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MIM_c29660 03bc15a6a01d050051fd70de5a76a1fd 371 PIRSF PIRSF002401 1 369 7.8E-133 T 12-10-2018 IPR035101 GTP-binding protein, Obg-type MIM_c29660 03bc15a6a01d050051fd70de5a76a1fd 371 SUPERFAMILY SSF82051 2 158 7.98E-56 T 12-10-2018 IPR036726 GTP1/OBG domain superfamily MIM_c29660 03bc15a6a01d050051fd70de5a76a1fd 371 SUPERFAMILY SSF52540 151 348 8.59E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c29660 03bc15a6a01d050051fd70de5a76a1fd 371 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 334 1.4E-137 T 12-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 MIM_c29660 03bc15a6a01d050051fd70de5a76a1fd 371 Pfam PF01926 50S ribosome-binding GTPase 161 289 3.5E-24 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 MIM_c29660 03bc15a6a01d050051fd70de5a76a1fd 371 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 7.4E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 MIM_c29660 03bc15a6a01d050051fd70de5a76a1fd 371 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 7.4E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 MIM_c29660 03bc15a6a01d050051fd70de5a76a1fd 371 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 7.4E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 MIM_c29660 03bc15a6a01d050051fd70de5a76a1fd 371 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 7.4E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 MIM_c29660 03bc15a6a01d050051fd70de5a76a1fd 371 Gene3D G3DSA:2.70.210.12 1 158 1.4E-58 T 12-10-2018 IPR036726 GTP1/OBG domain superfamily MIM_c29660 03bc15a6a01d050051fd70de5a76a1fd 371 Hamap MF_01454 GTPase Obg [obg]. 2 336 46.696 T 12-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 MIM_c29660 03bc15a6a01d050051fd70de5a76a1fd 371 Pfam PF01018 GTP1/OBG 4 158 2.7E-58 T 12-10-2018 IPR006169 GTP1/OBG domain MIM_c29660 03bc15a6a01d050051fd70de5a76a1fd 371 Gene3D G3DSA:3.40.50.300 159 349 6.3E-50 T 12-10-2018 MIM_c29660 03bc15a6a01d050051fd70de5a76a1fd 371 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 12-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 MIM_c29330 02814421cd8556f44daae30882f7eeba 179 Gene3D G3DSA:1.10.60.30 25 101 1.0E-20 T 12-10-2018 MIM_c29330 02814421cd8556f44daae30882f7eeba 179 Pfam PF04751 Protein of unknown function (DUF615) 15 173 3.8E-47 T 12-10-2018 IPR006839 Ribosome-associated, YjgA MIM_c29330 02814421cd8556f44daae30882f7eeba 179 Gene3D G3DSA:1.10.60.30 102 178 7.7E-19 T 12-10-2018 MIM_c29330 02814421cd8556f44daae30882f7eeba 179 PIRSF PIRSF016183 1 179 1.3E-53 T 12-10-2018 IPR006839 Ribosome-associated, YjgA MIM_c29330 02814421cd8556f44daae30882f7eeba 179 SUPERFAMILY SSF158710 27 173 1.96E-38 T 12-10-2018 IPR023153 PSPTO4464-like domain superfamily MIM_c08700 0e267e193d65f49960f977e31909e26a 302 Gene3D G3DSA:3.40.190.290 90 299 2.6E-27 T 12-10-2018 MIM_c08700 0e267e193d65f49960f977e31909e26a 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 5.1E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c08700 0e267e193d65f49960f977e31909e26a 302 Gene3D G3DSA:1.10.10.10 1 82 9.8E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c08700 0e267e193d65f49960f977e31909e26a 302 SUPERFAMILY SSF53850 90 290 1.05E-28 T 12-10-2018 MIM_c08700 0e267e193d65f49960f977e31909e26a 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.5E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c08700 0e267e193d65f49960f977e31909e26a 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.5E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c08700 0e267e193d65f49960f977e31909e26a 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.5E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c08700 0e267e193d65f49960f977e31909e26a 302 SUPERFAMILY SSF46785 1 78 1.5E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c08700 0e267e193d65f49960f977e31909e26a 302 Pfam PF03466 LysR substrate binding domain 88 289 8.6E-28 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c29410 aa4c1c62f57da8957b0a59a248a9ba1c 305 PIRSF PIRSF000401 1 304 1.7E-91 T 12-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 MIM_c29410 aa4c1c62f57da8957b0a59a248a9ba1c 305 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 1 302 31.859 T 12-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 MIM_c29410 aa4c1c62f57da8957b0a59a248a9ba1c 305 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 296 1.3E-64 T 12-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 MIM_c29410 aa4c1c62f57da8957b0a59a248a9ba1c 305 Gene3D G3DSA:3.40.50.150 106 305 3.0E-60 T 12-10-2018 MIM_c29410 aa4c1c62f57da8957b0a59a248a9ba1c 305 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 3 302 2.5E-86 T 12-10-2018 MIM_c29410 aa4c1c62f57da8957b0a59a248a9ba1c 305 SUPERFAMILY SSF53335 65 282 4.33E-39 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c15170 22c028335dc7592cdfbfa74ab919ee82 1297 Gene3D G3DSA:1.20.120.1080 444 548 3.1E-20 T 12-10-2018 MIM_c15170 22c028335dc7592cdfbfa74ab919ee82 1297 Gene3D G3DSA:3.40.50.300 230 418 8.7E-56 T 12-10-2018 MIM_c15170 22c028335dc7592cdfbfa74ab919ee82 1297 Pfam PF11898 Domain of unknown function (DUF3418) 705 1293 5.0E-199 T 12-10-2018 IPR024590 RNA helicase HrpA, C-terminal MIM_c15170 22c028335dc7592cdfbfa74ab919ee82 1297 SMART SM00487 46 235 1.0E-25 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MIM_c15170 22c028335dc7592cdfbfa74ab919ee82 1297 Pfam PF00271 Helicase conserved C-terminal domain 282 400 4.3E-13 T 12-10-2018 IPR001650 Helicase, C-terminal MIM_c15170 22c028335dc7592cdfbfa74ab919ee82 1297 Gene3D G3DSA:3.40.50.300 3 228 1.8E-75 T 12-10-2018 MIM_c15170 22c028335dc7592cdfbfa74ab919ee82 1297 Pfam PF04408 Helicase associated domain (HA2) 463 541 2.8E-20 T 12-10-2018 IPR007502 Helicase-associated domain GO:0004386 MIM_c15170 22c028335dc7592cdfbfa74ab919ee82 1297 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 15 1293 0.0 T 12-10-2018 IPR010222 RNA helicase HrpA GO:0004004 MIM_c15170 22c028335dc7592cdfbfa74ab919ee82 1297 SMART SM00847 460 550 3.4E-34 T 12-10-2018 IPR007502 Helicase-associated domain GO:0004386 MIM_c15170 22c028335dc7592cdfbfa74ab919ee82 1297 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 614 689 2.0E-15 T 12-10-2018 IPR011709 Domain of unknown function DUF1605 MIM_c15170 22c028335dc7592cdfbfa74ab919ee82 1297 SMART SM00490 299 400 1.7E-18 T 12-10-2018 IPR001650 Helicase, C-terminal MIM_c15170 22c028335dc7592cdfbfa74ab919ee82 1297 SUPERFAMILY SSF52540 45 558 1.17E-104 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c34400 f1c2a58dcb24110599e4f0830795a43d 268 SUPERFAMILY SSF52096 19 267 1.21E-66 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c34400 f1c2a58dcb24110599e4f0830795a43d 268 Pfam PF00378 Enoyl-CoA hydratase/isomerase 31 267 3.6E-44 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c34400 f1c2a58dcb24110599e4f0830795a43d 268 Gene3D G3DSA:1.10.12.10 211 268 1.8E-16 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MIM_c34400 f1c2a58dcb24110599e4f0830795a43d 268 Gene3D G3DSA:3.90.226.10 12 208 4.0E-49 T 12-10-2018 MIM_c11560 620d86e193fa4f459336f38b137dd6ab 642 Gene3D G3DSA:3.30.420.40 5 380 1.7E-163 T 12-10-2018 MIM_c11560 620d86e193fa4f459336f38b137dd6ab 642 SUPERFAMILY SSF100934 508 606 3.92E-19 T 12-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 MIM_c11560 620d86e193fa4f459336f38b137dd6ab 642 Gene3D G3DSA:1.20.1270.10 525 608 2.0E-25 T 12-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 MIM_c11560 620d86e193fa4f459336f38b137dd6ab 642 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 604 1.8E-285 T 12-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 MIM_c11560 620d86e193fa4f459336f38b137dd6ab 642 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.3E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MIM_c11560 620d86e193fa4f459336f38b137dd6ab 642 PRINTS PR00301 70kDa heat shock protein signature 335 351 2.3E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MIM_c11560 620d86e193fa4f459336f38b137dd6ab 642 PRINTS PR00301 70kDa heat shock protein signature 54 62 2.3E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MIM_c11560 620d86e193fa4f459336f38b137dd6ab 642 PRINTS PR00301 70kDa heat shock protein signature 199 209 2.3E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MIM_c11560 620d86e193fa4f459336f38b137dd6ab 642 PRINTS PR00301 70kDa heat shock protein signature 366 386 2.3E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MIM_c11560 620d86e193fa4f459336f38b137dd6ab 642 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.3E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MIM_c11560 620d86e193fa4f459336f38b137dd6ab 642 PRINTS PR00301 70kDa heat shock protein signature 138 158 2.3E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MIM_c11560 620d86e193fa4f459336f38b137dd6ab 642 PRINTS PR00301 70kDa heat shock protein signature 389 408 2.3E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MIM_c11560 620d86e193fa4f459336f38b137dd6ab 642 PRINTS PR00301 70kDa heat shock protein signature 470 486 2.3E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MIM_c11560 620d86e193fa4f459336f38b137dd6ab 642 Pfam PF00012 Hsp70 protein 4 604 8.2E-261 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MIM_c11560 620d86e193fa4f459336f38b137dd6ab 642 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 637 36.563 T 12-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 MIM_c11560 620d86e193fa4f459336f38b137dd6ab 642 Gene3D G3DSA:2.60.34.10 384 524 4.9E-66 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 MIM_c11560 620d86e193fa4f459336f38b137dd6ab 642 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MIM_c11560 620d86e193fa4f459336f38b137dd6ab 642 SUPERFAMILY SSF53067 188 383 1.3E-67 T 12-10-2018 MIM_c11560 620d86e193fa4f459336f38b137dd6ab 642 SUPERFAMILY SSF100920 385 541 1.02E-60 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 MIM_c11560 620d86e193fa4f459336f38b137dd6ab 642 Gene3D G3DSA:3.30.420.40 180 367 1.7E-163 T 12-10-2018 MIM_c11560 620d86e193fa4f459336f38b137dd6ab 642 Gene3D G3DSA:3.90.640.10 230 317 1.7E-163 T 12-10-2018 MIM_c11560 620d86e193fa4f459336f38b137dd6ab 642 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 193 206 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MIM_c11560 620d86e193fa4f459336f38b137dd6ab 642 SUPERFAMILY SSF53067 4 184 3.72E-63 T 12-10-2018 MIM_c11560 620d86e193fa4f459336f38b137dd6ab 642 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 338 352 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MIM_c32220 2ea9b6b69cede87c1a5a26d432c14bb6 577 Gene3D G3DSA:1.40.20.10 392 573 1.8E-20 T 12-10-2018 IPR038186 CHAD domain superfamily MIM_c32220 2ea9b6b69cede87c1a5a26d432c14bb6 577 Pfam PF05235 CHAD domain 244 535 6.1E-43 T 12-10-2018 IPR007899 CHAD domain MIM_c32220 2ea9b6b69cede87c1a5a26d432c14bb6 577 Pfam PF01928 CYTH domain 3 187 1.8E-18 T 12-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 MIM_c32220 2ea9b6b69cede87c1a5a26d432c14bb6 577 SMART SM00880 242 570 1.5E-36 T 12-10-2018 IPR007899 CHAD domain MIM_c32220 2ea9b6b69cede87c1a5a26d432c14bb6 577 SUPERFAMILY SSF55154 2 195 3.11E-30 T 12-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 MIM_c32220 2ea9b6b69cede87c1a5a26d432c14bb6 577 SMART SM01118 3 195 1.1E-25 T 12-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 MIM_c32220 2ea9b6b69cede87c1a5a26d432c14bb6 577 Gene3D G3DSA:2.40.320.10 2 190 7.9E-26 T 12-10-2018 MIM_c31110 4993b718378ac03d764e706060e6ac7f 170 Pfam PF01799 [2Fe-2S] binding domain 90 162 2.6E-25 T 12-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 MIM_c31110 4993b718378ac03d764e706060e6ac7f 170 SUPERFAMILY SSF54292 19 95 6.03E-23 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MIM_c31110 4993b718378ac03d764e706060e6ac7f 170 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 56 64 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MIM_c31110 4993b718378ac03d764e706060e6ac7f 170 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 24 69 3.1E-5 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MIM_c31110 4993b718378ac03d764e706060e6ac7f 170 Gene3D G3DSA:3.10.20.30 16 91 5.9E-26 T 12-10-2018 IPR012675 Beta-grasp domain superfamily MIM_c31110 4993b718378ac03d764e706060e6ac7f 170 Gene3D G3DSA:1.10.150.120 92 169 1.9E-25 T 12-10-2018 MIM_c31110 4993b718378ac03d764e706060e6ac7f 170 SUPERFAMILY SSF47741 101 167 9.68E-28 T 12-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily MIM_c35580 754f6e9a2721542337d01b927062d6c5 325 PIRSF PIRSF017082 5 323 1.2E-56 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c35580 754f6e9a2721542337d01b927062d6c5 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 43 320 1.2E-55 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c35580 754f6e9a2721542337d01b927062d6c5 325 SUPERFAMILY SSF53850 114 281 1.03E-7 T 12-10-2018 MIM_c35580 754f6e9a2721542337d01b927062d6c5 325 Gene3D G3DSA:3.40.190.10 122 246 2.9E-85 T 12-10-2018 MIM_c35580 754f6e9a2721542337d01b927062d6c5 325 Gene3D G3DSA:3.40.190.150 24 314 2.9E-85 T 12-10-2018 MIM_c20830 178a868cbeccd6474fa91690269793af 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 318 1.7E-68 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c20830 178a868cbeccd6474fa91690269793af 322 Gene3D G3DSA:3.40.190.10 125 247 1.1E-95 T 12-10-2018 MIM_c20830 178a868cbeccd6474fa91690269793af 322 PIRSF PIRSF017082 2 322 1.3E-75 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c20830 178a868cbeccd6474fa91690269793af 322 Gene3D G3DSA:3.40.190.150 28 311 1.1E-95 T 12-10-2018 MIM_c20830 178a868cbeccd6474fa91690269793af 322 SUPERFAMILY SSF53850 151 284 1.03E-7 T 12-10-2018 MIM_c12550 747fddb978373f451b263c197fd7d7f8 267 SUPERFAMILY SSF56300 11 222 6.54E-17 T 12-10-2018 MIM_c12550 747fddb978373f451b263c197fd7d7f8 267 Pfam PF00149 Calcineurin-like phosphoesterase 11 212 1.9E-5 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MIM_c12550 747fddb978373f451b263c197fd7d7f8 267 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 259 76.233 T 12-10-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 MIM_c12550 747fddb978373f451b263c197fd7d7f8 267 Gene3D G3DSA:3.60.21.10 11 228 2.5E-11 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like MIM_c12550 747fddb978373f451b263c197fd7d7f8 267 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 15 233 3.6E-57 T 12-10-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 MIM_c16760 38e4b362a82f9d3bb704dcf820bc4cbc 204 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 29 161 1.0E-26 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ MIM_c40560 8248ddbb7c3810795e5e4a5c50e1d546 139 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.4E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MIM_c40560 8248ddbb7c3810795e5e4a5c50e1d546 139 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.4E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MIM_c40560 8248ddbb7c3810795e5e4a5c50e1d546 139 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.4E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MIM_c40560 8248ddbb7c3810795e5e4a5c50e1d546 139 Gene3D G3DSA:3.30.70.920 54 139 6.0E-12 T 12-10-2018 MIM_c40560 8248ddbb7c3810795e5e4a5c50e1d546 139 Gene3D G3DSA:1.10.10.10 1 52 6.0E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c40560 8248ddbb7c3810795e5e4a5c50e1d546 139 SUPERFAMILY SSF46785 1 57 6.56E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c40560 8248ddbb7c3810795e5e4a5c50e1d546 139 SMART SM00344 1 107 6.9E-15 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MIM_c40560 8248ddbb7c3810795e5e4a5c50e1d546 139 Pfam PF01037 Lrp/AsnC ligand binding domain 71 136 1.7E-8 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MIM_c40560 8248ddbb7c3810795e5e4a5c50e1d546 139 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 47 2.4E-13 T 12-10-2018 MIM_c40560 8248ddbb7c3810795e5e4a5c50e1d546 139 SUPERFAMILY SSF54909 63 137 7.24E-11 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel MIM_c02350 39641b63377ee45f954e66f80afc57ee 387 Pfam PF01546 Peptidase family M20/M25/M40 72 383 4.8E-37 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 MIM_c02350 39641b63377ee45f954e66f80afc57ee 387 SUPERFAMILY SSF55031 180 285 1.24E-19 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain MIM_c02350 39641b63377ee45f954e66f80afc57ee 387 Gene3D G3DSA:3.30.70.360 180 297 6.8E-101 T 12-10-2018 MIM_c02350 39641b63377ee45f954e66f80afc57ee 387 Pfam PF07687 Peptidase dimerisation domain 176 286 2.4E-24 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain MIM_c02350 39641b63377ee45f954e66f80afc57ee 387 Gene3D G3DSA:3.40.630.10 14 373 6.8E-101 T 12-10-2018 MIM_c02350 39641b63377ee45f954e66f80afc57ee 387 SUPERFAMILY SSF53187 9 384 1.06E-54 T 12-10-2018 MIM_c02350 39641b63377ee45f954e66f80afc57ee 387 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 106 143 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 MIM_c02350 39641b63377ee45f954e66f80afc57ee 387 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 71 80 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 MIM_c02350 39641b63377ee45f954e66f80afc57ee 387 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 11 383 3.8E-111 T 12-10-2018 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 MIM_c14890 174b92e5be900cd1b7467a55a37abdd8 602 Gene3D G3DSA:3.40.50.300 384 599 2.6E-66 T 12-10-2018 MIM_c14890 174b92e5be900cd1b7467a55a37abdd8 602 SUPERFAMILY SSF88723 145 292 5.3E-12 T 12-10-2018 IPR029060 PIN-like domain superfamily MIM_c14890 174b92e5be900cd1b7467a55a37abdd8 602 SMART SM00670 144 278 1.1E-9 T 12-10-2018 IPR002716 PIN domain MIM_c14890 174b92e5be900cd1b7467a55a37abdd8 602 Pfam PF13638 PIN domain 146 290 4.0E-38 T 12-10-2018 IPR002716 PIN domain MIM_c14890 174b92e5be900cd1b7467a55a37abdd8 602 SUPERFAMILY SSF52540 385 580 1.0E-28 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c14890 174b92e5be900cd1b7467a55a37abdd8 602 Pfam PF02562 PhoH-like protein 386 593 1.8E-53 T 12-10-2018 IPR003714 PhoH-like protein GO:0005524 MIM_c14890 174b92e5be900cd1b7467a55a37abdd8 602 Gene3D G3DSA:3.40.50.1010 142 293 4.6E-24 T 12-10-2018 MIM_c09970 34c8ab18fe95e7112de3ceacfd77fc0c 165 TIGRFAM TIGR01935 NOT-MenG: RraA family 11 159 5.0E-55 T 12-10-2018 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 MIM_c09970 34c8ab18fe95e7112de3ceacfd77fc0c 165 Gene3D G3DSA:3.50.30.40 8 165 6.4E-58 T 12-10-2018 MIM_c09970 34c8ab18fe95e7112de3ceacfd77fc0c 165 Pfam PF03737 Aldolase/RraA 11 158 2.3E-42 T 12-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MIM_c09970 34c8ab18fe95e7112de3ceacfd77fc0c 165 SUPERFAMILY SSF89562 11 163 1.57E-44 T 12-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily MIM_c20390 8b9d33d6d5b2876202d7fc8e946b9d98 323 Gene3D G3DSA:3.40.190.10 126 248 3.6E-93 T 12-10-2018 MIM_c20390 8b9d33d6d5b2876202d7fc8e946b9d98 323 PIRSF PIRSF017082 1 321 6.4E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c20390 8b9d33d6d5b2876202d7fc8e946b9d98 323 SUPERFAMILY SSF53850 106 284 3.04E-6 T 12-10-2018 MIM_c20390 8b9d33d6d5b2876202d7fc8e946b9d98 323 Gene3D G3DSA:3.40.190.150 29 311 3.6E-93 T 12-10-2018 MIM_c20390 8b9d33d6d5b2876202d7fc8e946b9d98 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 308 6.0E-64 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c35130 5756cd4203ac99ea39d24ecac1130424 173 Pfam PF13302 Acetyltransferase (GNAT) domain 9 144 7.6E-23 T 12-10-2018 IPR000182 GNAT domain MIM_c35130 5756cd4203ac99ea39d24ecac1130424 173 Gene3D G3DSA:3.40.630.30 6 170 2.4E-51 T 12-10-2018 MIM_c35130 5756cd4203ac99ea39d24ecac1130424 173 SUPERFAMILY SSF55729 9 168 2.84E-42 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c00790 34dc18cf0695b660bfd97f2c15385579 294 ProDom PD128471 PLASMID Y4YQ BLL1803 TRANSMEMBRANE MLR6347 MEMBRANE ID195 16 294 3.0E-17 T 12-10-2018 MIM_c00790 34dc18cf0695b660bfd97f2c15385579 294 Pfam PF16693 Inner membrane component of T3SS, periplasmic domain 173 292 5.8E-8 T 12-10-2018 IPR032034 Yop protein translocation protein D, periplasmic domain MIM_c00790 34dc18cf0695b660bfd97f2c15385579 294 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 16 72 6.3E-12 T 12-10-2018 IPR032030 YscD, cytoplasmic domain MIM_c00790 34dc18cf0695b660bfd97f2c15385579 294 Gene3D G3DSA:2.60.200.20 10 118 2.2E-8 T 12-10-2018 MIM_c00790 34dc18cf0695b660bfd97f2c15385579 294 SUPERFAMILY SSF49879 9 70 1.67E-5 T 12-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 MIM_c22580 462c35d7ab4608fa600585fa77e0d139 107 Pfam PF14213 STAS-like domain of unknown function (DUF4325) 27 91 1.4E-20 T 12-10-2018 IPR025474 Domain of unknown function DUF4325 MIM_c32910 7353bba0de4299f82d6181493f0265f7 123 SUPERFAMILY SSF51230 3 121 3.27E-39 T 12-10-2018 IPR011053 Single hybrid motif MIM_c32910 7353bba0de4299f82d6181493f0265f7 123 Pfam PF01597 Glycine cleavage H-protein 7 121 4.4E-38 T 12-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate MIM_c32910 7353bba0de4299f82d6181493f0265f7 123 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 121 3.9E-39 T 12-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 MIM_c32910 7353bba0de4299f82d6181493f0265f7 123 Gene3D G3DSA:2.40.50.100 1 123 2.4E-43 T 12-10-2018 MIM_c32910 7353bba0de4299f82d6181493f0265f7 123 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MIM_c32910 7353bba0de4299f82d6181493f0265f7 123 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 123 33.621 T 12-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 MIM_c27720 8a340f5dcb7a17fa4964771c5211a7b3 1243 SUPERFAMILY SSF51126 659 801 1.44E-11 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor MIM_c27720 8a340f5dcb7a17fa4964771c5211a7b3 1243 Pfam PF03797 Autotransporter beta-domain 976 1223 1.5E-51 T 12-10-2018 IPR005546 Autotransporter beta-domain MIM_c27720 8a340f5dcb7a17fa4964771c5211a7b3 1243 SMART SM00869 973 1233 1.5E-39 T 12-10-2018 IPR005546 Autotransporter beta-domain MIM_c27720 8a340f5dcb7a17fa4964771c5211a7b3 1243 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 128 138 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site MIM_c27720 8a340f5dcb7a17fa4964771c5211a7b3 1243 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 765 1243 9.3E-39 T 12-10-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 MIM_c27720 8a340f5dcb7a17fa4964771c5211a7b3 1243 SUPERFAMILY SSF52743 59 495 5.5E-38 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 MIM_c27720 8a340f5dcb7a17fa4964771c5211a7b3 1243 Pfam PF12951 Passenger-associated-transport-repeat 688 716 4.4E-6 T 12-10-2018 IPR013425 Autotransporter-associated beta strand repeat MIM_c27720 8a340f5dcb7a17fa4964771c5211a7b3 1243 Pfam PF12951 Passenger-associated-transport-repeat 619 647 2.1E-7 T 12-10-2018 IPR013425 Autotransporter-associated beta strand repeat MIM_c27720 8a340f5dcb7a17fa4964771c5211a7b3 1243 SUPERFAMILY SSF51126 604 671 1.48E-5 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor MIM_c27720 8a340f5dcb7a17fa4964771c5211a7b3 1243 Pfam PF00082 Subtilase family 83 464 4.0E-21 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MIM_c27720 8a340f5dcb7a17fa4964771c5211a7b3 1243 PRINTS PR00723 Subtilisin serine protease family (S8) signature 124 137 5.1E-6 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related MIM_c27720 8a340f5dcb7a17fa4964771c5211a7b3 1243 PRINTS PR00723 Subtilisin serine protease family (S8) signature 80 99 5.1E-6 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related MIM_c27720 8a340f5dcb7a17fa4964771c5211a7b3 1243 PRINTS PR00723 Subtilisin serine protease family (S8) signature 413 429 5.1E-6 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related MIM_c27720 8a340f5dcb7a17fa4964771c5211a7b3 1243 Gene3D G3DSA:2.40.128.130 953 1243 1.5E-59 T 12-10-2018 IPR036709 Autotransporter beta-domain superfamily MIM_c27720 8a340f5dcb7a17fa4964771c5211a7b3 1243 SUPERFAMILY SSF103515 927 1243 1.29E-59 T 12-10-2018 IPR036709 Autotransporter beta-domain superfamily MIM_c27720 8a340f5dcb7a17fa4964771c5211a7b3 1243 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 618 649 2.0E-9 T 12-10-2018 IPR013425 Autotransporter-associated beta strand repeat MIM_c27720 8a340f5dcb7a17fa4964771c5211a7b3 1243 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 688 716 1.4E-6 T 12-10-2018 IPR013425 Autotransporter-associated beta strand repeat MIM_c36030 b4a1ece5fa1fc00c733ee8d5a94f6ad1 199 SUPERFAMILY SSF48498 87 198 1.63E-10 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MIM_c36030 b4a1ece5fa1fc00c733ee8d5a94f6ad1 199 Gene3D G3DSA:1.10.357.10 61 198 5.3E-23 T 12-10-2018 MIM_c36030 b4a1ece5fa1fc00c733ee8d5a94f6ad1 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 1.4E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c36030 b4a1ece5fa1fc00c733ee8d5a94f6ad1 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 1.4E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c36030 b4a1ece5fa1fc00c733ee8d5a94f6ad1 199 SUPERFAMILY SSF46689 14 88 6.67E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c36030 b4a1ece5fa1fc00c733ee8d5a94f6ad1 199 Gene3D G3DSA:1.10.10.60 16 60 1.7E-17 T 12-10-2018 MIM_c36030 b4a1ece5fa1fc00c733ee8d5a94f6ad1 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 7.1E-17 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c15010 f93fd228ebce8cc4cd8084410e113f85 391 Pfam PF00842 Alanine racemase, C-terminal domain 259 380 3.5E-42 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MIM_c15010 f93fd228ebce8cc4cd8084410e113f85 391 PRINTS PR00992 Alanine racemase signature 312 329 8.0E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MIM_c15010 f93fd228ebce8cc4cd8084410e113f85 391 PRINTS PR00992 Alanine racemase signature 274 289 8.0E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MIM_c15010 f93fd228ebce8cc4cd8084410e113f85 391 PRINTS PR00992 Alanine racemase signature 46 62 8.0E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MIM_c15010 f93fd228ebce8cc4cd8084410e113f85 391 PRINTS PR00992 Alanine racemase signature 291 306 8.0E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MIM_c15010 f93fd228ebce8cc4cd8084410e113f85 391 PRINTS PR00992 Alanine racemase signature 80 98 8.0E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MIM_c15010 f93fd228ebce8cc4cd8084410e113f85 391 PRINTS PR00992 Alanine racemase signature 177 188 8.0E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MIM_c15010 f93fd228ebce8cc4cd8084410e113f85 391 PRINTS PR00992 Alanine racemase signature 217 244 8.0E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MIM_c15010 f93fd228ebce8cc4cd8084410e113f85 391 PRINTS PR00992 Alanine racemase signature 140 152 8.0E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MIM_c15010 f93fd228ebce8cc4cd8084410e113f85 391 PRINTS PR00992 Alanine racemase signature 365 378 8.0E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MIM_c15010 f93fd228ebce8cc4cd8084410e113f85 391 TIGRFAM TIGR00492 alr: alanine racemase 7 380 5.1E-98 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MIM_c15010 f93fd228ebce8cc4cd8084410e113f85 391 SMART SM01005 258 383 2.2E-65 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MIM_c15010 f93fd228ebce8cc4cd8084410e113f85 391 Pfam PF01168 Alanine racemase, N-terminal domain 37 244 6.6E-53 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MIM_c15010 f93fd228ebce8cc4cd8084410e113f85 391 Hamap MF_01201 Alanine racemase. 2 383 31.28 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MIM_c15010 f93fd228ebce8cc4cd8084410e113f85 391 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 51 61 - T 12-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MIM_c15010 f93fd228ebce8cc4cd8084410e113f85 391 SUPERFAMILY SSF51419 42 259 3.05E-49 T 12-10-2018 IPR029066 PLP-binding barrel MIM_c15010 f93fd228ebce8cc4cd8084410e113f85 391 SUPERFAMILY SSF50621 251 383 2.55E-45 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MIM_c15010 f93fd228ebce8cc4cd8084410e113f85 391 Gene3D G3DSA:2.40.37.10 243 378 7.7E-105 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MIM_c15010 f93fd228ebce8cc4cd8084410e113f85 391 Gene3D G3DSA:3.20.20.10 45 242 7.7E-105 T 12-10-2018 IPR029066 PLP-binding barrel MIM_c40120 1da336cb3f4ec5b0f5855e103c8c032f 269 Gene3D G3DSA:3.20.20.60 1 268 3.7E-82 T 12-10-2018 MIM_c40120 1da336cb3f4ec5b0f5855e103c8c032f 269 PIRSF PIRSF015582 1 269 9.2E-82 T 12-10-2018 IPR011206 Citrate lyase beta subunit-like MIM_c40120 1da336cb3f4ec5b0f5855e103c8c032f 269 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 4 211 4.4E-33 T 12-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 MIM_c40120 1da336cb3f4ec5b0f5855e103c8c032f 269 SUPERFAMILY SSF51621 2 223 7.68E-57 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MIM_c07820 659b861bbf2b94d6fc2ac5702eb04a9c 102 SUPERFAMILY SSF47413 27 93 5.63E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c07820 659b861bbf2b94d6fc2ac5702eb04a9c 102 Pfam PF01381 Helix-turn-helix 46 91 2.4E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c07820 659b861bbf2b94d6fc2ac5702eb04a9c 102 Gene3D G3DSA:1.10.260.40 36 100 6.3E-7 T 12-10-2018 MIM_c07820 659b861bbf2b94d6fc2ac5702eb04a9c 102 TIGRFAM TIGR02684 dnstrm_HI1420: probable addiction module antidote protein 4 90 3.2E-34 T 12-10-2018 IPR014057 Uncharacterized protein HI1420 MIM_c07820 659b861bbf2b94d6fc2ac5702eb04a9c 102 SMART SM00530 39 92 1.4E-4 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c14590 345949eaf02dc072880a8ae888bae862 151 Pfam PF04977 Septum formation initiator 13 88 5.6E-19 T 12-10-2018 IPR007060 Septum formation initiator FtsL/DivIC MIM_c14590 345949eaf02dc072880a8ae888bae862 151 Hamap MF_00599 Cell division protein FtsB [ftsB]. 1 90 30.118 T 12-10-2018 IPR023081 Cell division protein FtsB MIM_c23710 151764294767167be73cba0d1fbfd9a2 329 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 64 2.5E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c23710 151764294767167be73cba0d1fbfd9a2 329 Gene3D G3DSA:1.10.10.10 1 86 1.3E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c23710 151764294767167be73cba0d1fbfd9a2 329 SUPERFAMILY SSF53850 92 304 1.49E-33 T 12-10-2018 MIM_c23710 151764294767167be73cba0d1fbfd9a2 329 Gene3D G3DSA:3.40.190.10 167 272 2.9E-86 T 12-10-2018 MIM_c23710 151764294767167be73cba0d1fbfd9a2 329 Gene3D G3DSA:3.40.190.10 92 308 2.9E-86 T 12-10-2018 MIM_c23710 151764294767167be73cba0d1fbfd9a2 329 Pfam PF03466 LysR substrate binding domain 90 266 1.5E-34 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c23710 151764294767167be73cba0d1fbfd9a2 329 SUPERFAMILY SSF46785 12 113 8.71E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c25940 30f4c78311c9ee8b4cd25f6b91de82d0 347 SUPERFAMILY SSF53850 27 335 3.26E-99 T 12-10-2018 MIM_c25940 30f4c78311c9ee8b4cd25f6b91de82d0 347 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 27 335 2.1E-124 T 12-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 MIM_c25940 30f4c78311c9ee8b4cd25f6b91de82d0 347 PIRSF PIRSF002756 2 338 1.8E-110 T 12-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 MIM_c25940 30f4c78311c9ee8b4cd25f6b91de82d0 347 Pfam PF12849 PBP superfamily domain 22 307 2.6E-63 T 12-10-2018 IPR024370 PBP domain MIM_c25940 30f4c78311c9ee8b4cd25f6b91de82d0 347 Gene3D G3DSA:3.40.190.10 101 277 6.0E-124 T 12-10-2018 MIM_c25940 30f4c78311c9ee8b4cd25f6b91de82d0 347 Gene3D G3DSA:3.40.190.10 28 324 6.0E-124 T 12-10-2018 MIM_c31620 fbf879cd36a8a719dd2dafeddf347aae 425 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 180 420 1.1E-27 T 12-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 MIM_c31620 fbf879cd36a8a719dd2dafeddf347aae 425 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 81 101 8.3E-16 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 MIM_c31620 fbf879cd36a8a719dd2dafeddf347aae 425 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 181 203 8.3E-16 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 MIM_c31620 fbf879cd36a8a719dd2dafeddf347aae 425 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 28 53 8.3E-16 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 MIM_c31620 fbf879cd36a8a719dd2dafeddf347aae 425 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 102 122 8.3E-16 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 MIM_c31620 fbf879cd36a8a719dd2dafeddf347aae 425 Pfam PF00355 Rieske [2Fe-2S] domain 43 129 1.0E-16 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MIM_c31620 fbf879cd36a8a719dd2dafeddf347aae 425 SUPERFAMILY SSF50022 8 157 3.8E-44 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MIM_c31620 fbf879cd36a8a719dd2dafeddf347aae 425 Gene3D G3DSA:2.102.10.10 41 164 5.8E-64 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MIM_c31620 fbf879cd36a8a719dd2dafeddf347aae 425 SUPERFAMILY SSF55961 163 422 2.51E-30 T 12-10-2018 MIM_c31620 fbf879cd36a8a719dd2dafeddf347aae 425 Gene3D G3DSA:3.90.380.10 23 392 5.8E-64 T 12-10-2018 MIM_c26540 f4109840efdc02f52dcf920b00627fbc 155 Hamap MF_00771 UPF0310 protein . 2 137 27.847 T 12-10-2018 IPR022996 Uncharacterised protein family UPF0310 MIM_c26540 f4109840efdc02f52dcf920b00627fbc 155 SUPERFAMILY SSF88697 3 137 1.64E-31 T 12-10-2018 IPR015947 PUA-like superfamily MIM_c26540 f4109840efdc02f52dcf920b00627fbc 155 Pfam PF01878 EVE domain 3 135 7.2E-19 T 12-10-2018 IPR002740 EVE domain MIM_c26540 f4109840efdc02f52dcf920b00627fbc 155 Gene3D G3DSA:3.10.590.10 1 135 2.8E-30 T 12-10-2018 MIM_c02520 a58707c178fcddfccfacbd46f0da74c6 328 SUPERFAMILY SSF53850 115 290 1.38E-15 T 12-10-2018 MIM_c02520 a58707c178fcddfccfacbd46f0da74c6 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 323 3.6E-71 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c02520 a58707c178fcddfccfacbd46f0da74c6 328 Gene3D G3DSA:3.40.190.150 31 318 3.2E-102 T 12-10-2018 MIM_c02520 a58707c178fcddfccfacbd46f0da74c6 328 PIRSF PIRSF017082 1 328 2.3E-82 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c02520 a58707c178fcddfccfacbd46f0da74c6 328 Gene3D G3DSA:3.40.190.10 130 253 3.2E-102 T 12-10-2018 MIM_c19210 506d99ccb220d582fb5313b6a6244eb1 566 TIGRFAM TIGR01348 PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase 96 565 5.9E-189 T 12-10-2018 IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex GO:0004742|GO:0006096|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 MIM_c19210 506d99ccb220d582fb5313b6a6244eb1 566 Gene3D G3DSA:4.10.320.10 263 305 3.2E-17 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MIM_c19210 506d99ccb220d582fb5313b6a6244eb1 566 Gene3D G3DSA:2.40.50.100 124 201 3.0E-19 T 12-10-2018 MIM_c19210 506d99ccb220d582fb5313b6a6244eb1 566 Gene3D G3DSA:2.40.50.100 3 82 4.2E-21 T 12-10-2018 MIM_c19210 506d99ccb220d582fb5313b6a6244eb1 566 Gene3D G3DSA:3.30.559.10 324 566 7.8E-92 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MIM_c19210 506d99ccb220d582fb5313b6a6244eb1 566 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 148 177 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MIM_c19210 506d99ccb220d582fb5313b6a6244eb1 566 SUPERFAMILY SSF52777 331 565 1.51E-82 T 12-10-2018 MIM_c19210 506d99ccb220d582fb5313b6a6244eb1 566 SUPERFAMILY SSF47005 258 301 4.32E-11 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MIM_c19210 506d99ccb220d582fb5313b6a6244eb1 566 SUPERFAMILY SSF51230 124 216 6.67E-21 T 12-10-2018 IPR011053 Single hybrid motif MIM_c19210 506d99ccb220d582fb5313b6a6244eb1 566 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MIM_c19210 506d99ccb220d582fb5313b6a6244eb1 566 Pfam PF02817 e3 binding domain 262 297 1.3E-13 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 MIM_c19210 506d99ccb220d582fb5313b6a6244eb1 566 SUPERFAMILY SSF51230 3 96 6.02E-24 T 12-10-2018 IPR011053 Single hybrid motif MIM_c19210 506d99ccb220d582fb5313b6a6244eb1 566 Pfam PF00364 Biotin-requiring enzyme 6 77 2.8E-21 T 12-10-2018 IPR000089 Biotin/lipoyl attachment MIM_c19210 506d99ccb220d582fb5313b6a6244eb1 566 Pfam PF00364 Biotin-requiring enzyme 126 197 1.8E-20 T 12-10-2018 IPR000089 Biotin/lipoyl attachment MIM_c19210 506d99ccb220d582fb5313b6a6244eb1 566 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 341 565 2.7E-79 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 MIM_c34790 10216a23708b3f241b5ccf9fd9274a22 984 SUPERFAMILY SSF141571 663 799 1.5E-27 T 12-10-2018 MIM_c34790 10216a23708b3f241b5ccf9fd9274a22 984 Pfam PF00805 Pentapeptide repeats (8 copies) 695 733 1.9E-11 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c34790 10216a23708b3f241b5ccf9fd9274a22 984 Pfam PF00805 Pentapeptide repeats (8 copies) 924 957 1.8E-6 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c34790 10216a23708b3f241b5ccf9fd9274a22 984 Pfam PF00805 Pentapeptide repeats (8 copies) 860 899 1.1E-8 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c34790 10216a23708b3f241b5ccf9fd9274a22 984 SUPERFAMILY SSF141571 854 960 3.66E-22 T 12-10-2018 MIM_c34790 10216a23708b3f241b5ccf9fd9274a22 984 Gene3D G3DSA:2.160.20.80 843 983 9.8E-24 T 12-10-2018 MIM_c34790 10216a23708b3f241b5ccf9fd9274a22 984 Pfam PF09937 Uncharacterized protein conserved in bacteria (DUF2169) 20 349 1.5E-91 T 12-10-2018 IPR018683 Domain of unknown function DUF2169 MIM_c34790 10216a23708b3f241b5ccf9fd9274a22 984 Gene3D G3DSA:2.160.20.80 636 818 1.7E-31 T 12-10-2018 MIM_c06540 dc2149e3d0c58097b729798bd3f40d95 247 PIRSF PIRSF029287 8 246 5.9E-51 T 12-10-2018 IPR017748 T6S-associated protein TagF MIM_c06540 dc2149e3d0c58097b729798bd3f40d95 247 Pfam PF09867 Uncharacterized protein conserved in bacteria (DUF2094) 14 146 2.1E-42 T 12-10-2018 IPR017748 T6S-associated protein TagF MIM_c06540 dc2149e3d0c58097b729798bd3f40d95 247 Gene3D G3DSA:3.40.1730.10 10 245 7.5E-44 T 12-10-2018 IPR038225 T6S-associated protein TagF superfamily MIM_c06540 dc2149e3d0c58097b729798bd3f40d95 247 TIGRFAM TIGR03373 VI_minor_4: type VI secretion-associated protein, BMA_A0400 family 14 147 1.5E-33 T 12-10-2018 IPR017748 T6S-associated protein TagF MIM_c27590 145ae4c52ee363a7a481187d72d2a0e6 158 Gene3D G3DSA:3.10.129.10 4 143 7.5E-25 T 12-10-2018 MIM_c27590 145ae4c52ee363a7a481187d72d2a0e6 158 SUPERFAMILY SSF54637 8 144 2.33E-24 T 12-10-2018 IPR029069 HotDog domain superfamily MIM_c27590 145ae4c52ee363a7a481187d72d2a0e6 158 Pfam PF13279 Thioesterase-like superfamily 19 134 2.4E-7 T 12-10-2018 MIM_c06480 72238c19a8fdd0eecd7a5c947a6d2908 370 Pfam PF00498 FHA domain 24 93 2.9E-4 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MIM_c06480 72238c19a8fdd0eecd7a5c947a6d2908 370 SUPERFAMILY SSF49879 9 110 3.44E-11 T 12-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 MIM_c06480 72238c19a8fdd0eecd7a5c947a6d2908 370 Gene3D G3DSA:2.60.200.20 2 105 1.9E-7 T 12-10-2018 MIM_c00020 b684a6b5459a1eddddbd1afec62d5eba 369 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 247 368 6.1E-21 T 12-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 MIM_c00020 b684a6b5459a1eddddbd1afec62d5eba 369 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 6 120 1.1E-26 T 12-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 MIM_c00020 b684a6b5459a1eddddbd1afec62d5eba 369 SUPERFAMILY SSF55979 247 369 1.42E-28 T 12-10-2018 MIM_c00020 b684a6b5459a1eddddbd1afec62d5eba 369 SUPERFAMILY SSF55979 127 246 2.24E-28 T 12-10-2018 MIM_c00020 b684a6b5459a1eddddbd1afec62d5eba 369 Gene3D G3DSA:3.10.150.10 5 244 7.0E-104 T 12-10-2018 MIM_c00020 b684a6b5459a1eddddbd1afec62d5eba 369 Pfam PF02767 DNA polymerase III beta subunit, central domain 132 245 9.1E-30 T 12-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 MIM_c00020 b684a6b5459a1eddddbd1afec62d5eba 369 SMART SM00480 18 365 4.2E-85 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 MIM_c00020 b684a6b5459a1eddddbd1afec62d5eba 369 SUPERFAMILY SSF55979 5 118 1.02E-20 T 12-10-2018 MIM_c00020 b684a6b5459a1eddddbd1afec62d5eba 369 PIRSF PIRSF000804 1 369 3.9E-104 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 MIM_c00020 b684a6b5459a1eddddbd1afec62d5eba 369 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 7 368 9.2E-86 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 MIM_c00020 b684a6b5459a1eddddbd1afec62d5eba 369 Gene3D G3DSA:3.70.10.10 140 367 7.0E-104 T 12-10-2018 MIM_c13270 75a800ec1435566b844d266462502356 86 SUPERFAMILY SSF109910 3 81 1.7E-19 T 12-10-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily MIM_c13270 75a800ec1435566b844d266462502356 86 Pfam PF03937 Flavinator of succinate dehydrogenase 9 78 3.5E-20 T 12-10-2018 IPR005631 Flavinator of succinate dehydrogenase MIM_c13270 75a800ec1435566b844d266462502356 86 Gene3D G3DSA:1.10.150.250 1 85 2.3E-19 T 12-10-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily MIM_c40090 035c7c62e2fae98f0572480666d5f1f0 249 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 225 4.2E-16 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MIM_c40090 035c7c62e2fae98f0572480666d5f1f0 249 SUPERFAMILY SSF52172 1 183 1.06E-30 T 12-10-2018 IPR011006 CheY-like superfamily MIM_c40090 035c7c62e2fae98f0572480666d5f1f0 249 Gene3D G3DSA:3.40.50.2300 1 124 6.5E-27 T 12-10-2018 MIM_c40090 035c7c62e2fae98f0572480666d5f1f0 249 SMART SM00448 1 114 3.1E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c40090 035c7c62e2fae98f0572480666d5f1f0 249 Pfam PF00072 Response regulator receiver domain 3 114 1.6E-20 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c40090 035c7c62e2fae98f0572480666d5f1f0 249 SMART SM00862 149 225 5.0E-17 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MIM_c40090 035c7c62e2fae98f0572480666d5f1f0 249 Gene3D G3DSA:1.10.10.10 125 231 5.0E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c21830 f1f8339b2325757af2d34d7d7de65597 119 Gene3D G3DSA:1.10.720.90 2 55 5.6E-25 T 12-10-2018 MIM_c21830 f1f8339b2325757af2d34d7d7de65597 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 6.0E-49 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c21830 f1f8339b2325757af2d34d7d7de65597 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 29.976 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c21830 f1f8339b2325757af2d34d7d7de65597 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 71 3.0E-22 T 12-10-2018 MIM_c21830 f1f8339b2325757af2d34d7d7de65597 119 Gene3D G3DSA:1.10.1900.20 56 118 6.0E-29 T 12-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c21830 f1f8339b2325757af2d34d7d7de65597 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c21830 f1f8339b2325757af2d34d7d7de65597 119 SUPERFAMILY SSF74731 2 117 2.49E-49 T 12-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c21830 f1f8339b2325757af2d34d7d7de65597 119 Pfam PF00453 Ribosomal protein L20 3 108 1.4E-48 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c21830 f1f8339b2325757af2d34d7d7de65597 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 8.5E-39 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c21830 f1f8339b2325757af2d34d7d7de65597 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 8.5E-39 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c21830 f1f8339b2325757af2d34d7d7de65597 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 8.5E-39 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c20710 1dfa12253fbce657e0109087ba3957af 415 Pfam PF02515 CoA-transferase family III 25 391 2.0E-115 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 MIM_c20710 1dfa12253fbce657e0109087ba3957af 415 Gene3D G3DSA:3.30.1540.10 246 337 1.0E-112 T 12-10-2018 MIM_c20710 1dfa12253fbce657e0109087ba3957af 415 SUPERFAMILY SSF89796 24 415 1.44E-115 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c20710 1dfa12253fbce657e0109087ba3957af 415 Gene3D G3DSA:3.40.50.10540 25 358 1.0E-112 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c32290 1849912b2bc2ab3a23ca80ff2e6c43a6 136 Gene3D G3DSA:1.10.10.690 1 136 1.7E-34 T 12-10-2018 IPR027405 YidB-like MIM_c32290 1849912b2bc2ab3a23ca80ff2e6c43a6 136 SUPERFAMILY SSF140804 14 135 3.27E-33 T 12-10-2018 IPR027405 YidB-like MIM_c32290 1849912b2bc2ab3a23ca80ff2e6c43a6 136 Pfam PF06078 Bacterial protein of unknown function (DUF937) 3 108 1.2E-10 T 12-10-2018 IPR009282 Protein of unknown function DUF937 MIM_c13820 3fdf75ce9ac8a6d39d2e140e429eef4b 391 Gene3D G3DSA:1.10.540.10 2 122 5.9E-25 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c13820 3fdf75ce9ac8a6d39d2e140e429eef4b 391 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 217 8.5E-20 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MIM_c13820 3fdf75ce9ac8a6d39d2e140e429eef4b 391 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 375 5.4E-38 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MIM_c13820 3fdf75ce9ac8a6d39d2e140e429eef4b 391 Gene3D G3DSA:2.40.110.10 123 234 2.7E-30 T 12-10-2018 MIM_c13820 3fdf75ce9ac8a6d39d2e140e429eef4b 391 Gene3D G3DSA:1.20.140.10 235 384 4.4E-44 T 12-10-2018 MIM_c13820 3fdf75ce9ac8a6d39d2e140e429eef4b 391 SUPERFAMILY SSF56645 5 229 1.05E-54 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c13820 3fdf75ce9ac8a6d39d2e140e429eef4b 391 SUPERFAMILY SSF47203 229 377 6.28E-43 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c13820 3fdf75ce9ac8a6d39d2e140e429eef4b 391 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 120 2.1E-22 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c37310 e9612548e21b366fbed3dfd58de1170e 763 SUPERFAMILY SSF51735 163 438 1.18E-82 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c37310 e9612548e21b366fbed3dfd58de1170e 763 SMART SM01274 18 151 1.2E-75 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MIM_c37310 e9612548e21b366fbed3dfd58de1170e 763 SUPERFAMILY SSF53223 10 161 5.11E-50 T 12-10-2018 MIM_c37310 e9612548e21b366fbed3dfd58de1170e 763 Gene3D G3DSA:3.40.50.10380 2 160 2.3E-66 T 12-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 MIM_c37310 e9612548e21b366fbed3dfd58de1170e 763 Pfam PF01515 Phosphate acetyl/butaryl transferase 429 755 1.1E-92 T 12-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MIM_c37310 e9612548e21b366fbed3dfd58de1170e 763 Gene3D G3DSA:3.40.50.720 161 442 1.1E-79 T 12-10-2018 MIM_c37310 e9612548e21b366fbed3dfd58de1170e 763 Pfam PF03949 Malic enzyme, NAD binding domain 165 357 1.1E-18 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MIM_c37310 e9612548e21b366fbed3dfd58de1170e 763 SMART SM00919 163 400 8.8E-137 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MIM_c37310 e9612548e21b366fbed3dfd58de1170e 763 Gene3D G3DSA:3.40.50.10750 577 731 2.8E-94 T 12-10-2018 MIM_c37310 e9612548e21b366fbed3dfd58de1170e 763 SUPERFAMILY SSF53659 430 760 6.17E-85 T 12-10-2018 MIM_c37310 e9612548e21b366fbed3dfd58de1170e 763 Pfam PF00390 Malic enzyme, N-terminal domain 19 151 4.7E-25 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MIM_c37310 e9612548e21b366fbed3dfd58de1170e 763 PIRSF PIRSF036684 1 763 0.0 T 12-10-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 MIM_c37310 e9612548e21b366fbed3dfd58de1170e 763 Gene3D G3DSA:3.40.50.10950 448 755 2.8E-94 T 12-10-2018 MIM_c38970 aa3b51e4227290e324abf3fce2397492 121 Pfam PF00416 Ribosomal protein S13/S18 3 108 2.0E-31 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c38970 aa3b51e4227290e324abf3fce2397492 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 26.693 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c38970 aa3b51e4227290e324abf3fce2397492 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 3.7E-51 T 12-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c38970 aa3b51e4227290e324abf3fce2397492 121 Gene3D G3DSA:4.10.910.10 72 117 1.6E-23 T 12-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c38970 aa3b51e4227290e324abf3fce2397492 121 PIRSF PIRSF002134 1 121 1.3E-39 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c38970 aa3b51e4227290e324abf3fce2397492 121 Gene3D G3DSA:1.10.8.50 1 71 6.9E-27 T 12-10-2018 MIM_c38970 aa3b51e4227290e324abf3fce2397492 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 12-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c38970 aa3b51e4227290e324abf3fce2397492 121 SUPERFAMILY SSF46946 2 114 1.18E-43 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 MIM_c16750 483894b376882f56aad5de98bdd99df8 366 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 43 325 1.1E-58 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 MIM_c16750 483894b376882f56aad5de98bdd99df8 366 PIRSF PIRSF039026 1 358 5.3E-121 T 12-10-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like MIM_c16750 483894b376882f56aad5de98bdd99df8 366 Gene3D G3DSA:3.40.190.10 155 325 1.1E-123 T 12-10-2018 MIM_c16750 483894b376882f56aad5de98bdd99df8 366 Gene3D G3DSA:3.40.190.170 36 339 1.1E-123 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily MIM_c16750 483894b376882f56aad5de98bdd99df8 366 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 28 8.8E-4 T 12-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal MIM_c18920 6da2fb2cb2d1e9ad016a7cb5abc9c8da 197 Gene3D G3DSA:3.90.950.10 1 196 1.5E-68 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MIM_c18920 6da2fb2cb2d1e9ad016a7cb5abc9c8da 197 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 191 2.8E-49 T 12-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 MIM_c18920 6da2fb2cb2d1e9ad016a7cb5abc9c8da 197 Pfam PF01725 Ham1 family 3 191 2.6E-50 T 12-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 MIM_c18920 6da2fb2cb2d1e9ad016a7cb5abc9c8da 197 SUPERFAMILY SSF52972 1 193 1.28E-63 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MIM_c18920 6da2fb2cb2d1e9ad016a7cb5abc9c8da 197 Hamap MF_01405 dITP/XTP pyrophosphatase. 1 196 45.617 T 12-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 MIM_c08950 c5a7099363058b663d3696ecfff1bbaa 588 SMART SM00382 364 550 3.6E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c08950 c5a7099363058b663d3696ecfff1bbaa 588 SUPERFAMILY SSF52540 331 574 1.96E-84 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c08950 c5a7099363058b663d3696ecfff1bbaa 588 Gene3D G3DSA:3.40.50.300 336 582 5.2E-86 T 12-10-2018 MIM_c08950 c5a7099363058b663d3696ecfff1bbaa 588 Gene3D G3DSA:1.20.1560.10 6 324 1.8E-41 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MIM_c08950 c5a7099363058b663d3696ecfff1bbaa 588 SUPERFAMILY SSF90123 12 328 7.72E-46 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MIM_c08950 c5a7099363058b663d3696ecfff1bbaa 588 ProSitePatterns PS00211 ABC transporters family signature. 476 490 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c08950 c5a7099363058b663d3696ecfff1bbaa 588 Pfam PF00664 ABC transporter transmembrane region 62 286 2.3E-22 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MIM_c08950 c5a7099363058b663d3696ecfff1bbaa 588 Pfam PF00005 ABC transporter 355 504 1.3E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c20880 688a08ab48ebb8d127c195fe6fb73d74 410 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 121 2.9E-24 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c20880 688a08ab48ebb8d127c195fe6fb73d74 410 Gene3D G3DSA:2.40.110.10 126 240 5.2E-29 T 12-10-2018 MIM_c20880 688a08ab48ebb8d127c195fe6fb73d74 410 Gene3D G3DSA:1.10.540.10 3 124 2.1E-29 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c20880 688a08ab48ebb8d127c195fe6fb73d74 410 SUPERFAMILY SSF47203 233 388 3.54E-46 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c20880 688a08ab48ebb8d127c195fe6fb73d74 410 Gene3D G3DSA:1.20.140.10 241 388 2.2E-43 T 12-10-2018 MIM_c20880 688a08ab48ebb8d127c195fe6fb73d74 410 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 383 7.7E-40 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MIM_c20880 688a08ab48ebb8d127c195fe6fb73d74 410 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 213 9.2E-14 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MIM_c20880 688a08ab48ebb8d127c195fe6fb73d74 410 SUPERFAMILY SSF56645 8 248 1.57E-63 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c17610 746ba8bc63f0f0ceafd974316dff0616 378 Pfam PF00155 Aminotransferase class I and II 42 359 1.3E-52 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MIM_c17610 746ba8bc63f0f0ceafd974316dff0616 378 Gene3D G3DSA:3.90.1150.10 39 361 4.2E-98 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c17610 746ba8bc63f0f0ceafd974316dff0616 378 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 11 369 50.459 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 MIM_c17610 746ba8bc63f0f0ceafd974316dff0616 378 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 15 366 2.8E-87 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 MIM_c17610 746ba8bc63f0f0ceafd974316dff0616 378 Gene3D G3DSA:3.40.640.10 54 278 4.2E-98 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c17610 746ba8bc63f0f0ceafd974316dff0616 378 SUPERFAMILY SSF53383 21 367 5.35E-74 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c17610 746ba8bc63f0f0ceafd974316dff0616 378 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 230 239 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 MIM_c24050 59c44b24a4984277c40801ab9123686d 319 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 43 315 3.8E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c24050 59c44b24a4984277c40801ab9123686d 319 Gene3D G3DSA:3.40.190.10 121 244 1.4E-110 T 12-10-2018 MIM_c24050 59c44b24a4984277c40801ab9123686d 319 Gene3D G3DSA:3.40.190.150 24 309 1.4E-110 T 12-10-2018 MIM_c24050 59c44b24a4984277c40801ab9123686d 319 SUPERFAMILY SSF53850 110 279 2.17E-15 T 12-10-2018 MIM_c24050 59c44b24a4984277c40801ab9123686d 319 PIRSF PIRSF017082 3 319 3.1E-85 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c36910 084cf6fda0de08df3f8cfd31ac961738 767 SUPERFAMILY SSF81653 256 352 1.44E-30 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 MIM_c36910 084cf6fda0de08df3f8cfd31ac961738 767 Gene3D G3DSA:3.40.1110.10 465 585 7.9E-93 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MIM_c36910 084cf6fda0de08df3f8cfd31ac961738 767 Gene3D G3DSA:3.40.50.1000 435 705 7.9E-93 T 12-10-2018 IPR023214 HAD superfamily MIM_c36910 084cf6fda0de08df3f8cfd31ac961738 767 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 302 316 1.5E-24 T 12-10-2018 MIM_c36910 084cf6fda0de08df3f8cfd31ac961738 767 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 600 610 1.5E-24 T 12-10-2018 MIM_c36910 084cf6fda0de08df3f8cfd31ac961738 767 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 653 672 1.5E-24 T 12-10-2018 MIM_c36910 084cf6fda0de08df3f8cfd31ac961738 767 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 454 468 1.5E-24 T 12-10-2018 MIM_c36910 084cf6fda0de08df3f8cfd31ac961738 767 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 676 688 1.5E-24 T 12-10-2018 MIM_c36910 084cf6fda0de08df3f8cfd31ac961738 767 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 167 763 1.5E-179 T 12-10-2018 MIM_c36910 084cf6fda0de08df3f8cfd31ac961738 767 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 456 462 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MIM_c36910 084cf6fda0de08df3f8cfd31ac961738 767 Pfam PF00403 Heavy-metal-associated domain 27 85 2.2E-12 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MIM_c36910 084cf6fda0de08df3f8cfd31ac961738 767 PRINTS PR00943 Copper-transporting ATPase signature 726 740 1.0E-8 T 12-10-2018 MIM_c36910 084cf6fda0de08df3f8cfd31ac961738 767 PRINTS PR00943 Copper-transporting ATPase signature 375 389 1.0E-8 T 12-10-2018 MIM_c36910 084cf6fda0de08df3f8cfd31ac961738 767 PRINTS PR00943 Copper-transporting ATPase signature 222 241 1.0E-8 T 12-10-2018 MIM_c36910 084cf6fda0de08df3f8cfd31ac961738 767 PRINTS PR00943 Copper-transporting ATPase signature 170 189 1.0E-8 T 12-10-2018 MIM_c36910 084cf6fda0de08df3f8cfd31ac961738 767 Gene3D G3DSA:2.70.150.20 246 356 7.6E-42 T 12-10-2018 MIM_c36910 084cf6fda0de08df3f8cfd31ac961738 767 ProSitePatterns PS01047 Heavy-metal-associated domain. 29 58 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 MIM_c36910 084cf6fda0de08df3f8cfd31ac961738 767 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 185 762 9.7E-194 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MIM_c36910 084cf6fda0de08df3f8cfd31ac961738 767 SUPERFAMILY SSF56784 452 760 2.18E-60 T 12-10-2018 IPR036412 HAD-like superfamily MIM_c36910 084cf6fda0de08df3f8cfd31ac961738 767 SUPERFAMILY SSF55008 20 93 4.71E-19 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 MIM_c36910 084cf6fda0de08df3f8cfd31ac961738 767 SUPERFAMILY SSF81665 201 741 6.28E-16 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 MIM_c36910 084cf6fda0de08df3f8cfd31ac961738 767 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 224 731 6.5E-97 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MIM_c36910 084cf6fda0de08df3f8cfd31ac961738 767 Gene3D G3DSA:3.30.70.100 24 91 1.3E-20 T 12-10-2018 MIM_c36910 084cf6fda0de08df3f8cfd31ac961738 767 Pfam PF00122 E1-E2 ATPase 253 433 8.9E-60 T 12-10-2018 MIM_c36910 084cf6fda0de08df3f8cfd31ac961738 767 Pfam PF00702 haloacid dehalogenase-like hydrolase 450 667 4.6E-44 T 12-10-2018 MIM_c23050 8addb6f1480b119b0ecad47adc896d15 99 Pfam PF01337 Barstar (barnase inhibitor) 14 91 5.1E-19 T 12-10-2018 IPR000468 Barstar (barnase inhibitor) MIM_c23050 8addb6f1480b119b0ecad47adc896d15 99 SUPERFAMILY SSF52038 14 94 1.31E-18 T 12-10-2018 IPR035905 Barstar-like superfamily MIM_c23050 8addb6f1480b119b0ecad47adc896d15 99 Gene3D G3DSA:3.30.370.10 13 99 1.7E-23 T 12-10-2018 IPR035905 Barstar-like superfamily MIM_c29450 2b9041d937eccebcce4efefac24654e1 176 Pfam PF00578 AhpC/TSA family 46 152 4.4E-17 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MIM_c29450 2b9041d937eccebcce4efefac24654e1 176 SUPERFAMILY SSF52833 46 175 1.13E-24 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c29450 2b9041d937eccebcce4efefac24654e1 176 ProSitePatterns PS00194 Thioredoxin family active site. 68 86 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MIM_c29450 2b9041d937eccebcce4efefac24654e1 176 Gene3D G3DSA:3.40.30.10 47 175 3.4E-27 T 12-10-2018 MIM_c36300 117d4c504cc672f42d661bd68291f65d 162 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 7 158 39.212 T 12-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 MIM_c36300 117d4c504cc672f42d661bd68291f65d 162 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 3 73 2.8E-8 T 12-10-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MIM_c36300 117d4c504cc672f42d661bd68291f65d 162 SUPERFAMILY SSF53155 4 83 1.39E-18 T 12-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MIM_c36300 117d4c504cc672f42d661bd68291f65d 162 Gene3D G3DSA:3.30.160.70 2 74 3.1E-18 T 12-10-2018 MIM_c36300 117d4c504cc672f42d661bd68291f65d 162 Gene3D G3DSA:1.10.10.10 75 159 1.6E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c36300 117d4c504cc672f42d661bd68291f65d 162 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 78 157 9.6E-33 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MIM_c36300 117d4c504cc672f42d661bd68291f65d 162 SUPERFAMILY SSF46767 77 158 1.96E-30 T 12-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 MIM_c36300 117d4c504cc672f42d661bd68291f65d 162 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 79 158 5.5E-31 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MIM_c38960 d3237c1bdd3bd02c5ee0522b6973ca50 132 Gene3D G3DSA:3.30.420.80 5 132 1.4E-53 T 12-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 MIM_c38960 d3237c1bdd3bd02c5ee0522b6973ca50 132 SUPERFAMILY SSF53137 18 132 3.92E-47 T 12-10-2018 MIM_c38960 d3237c1bdd3bd02c5ee0522b6973ca50 132 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 10 132 32.479 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MIM_c38960 d3237c1bdd3bd02c5ee0522b6973ca50 132 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 13 129 2.1E-54 T 12-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c38960 d3237c1bdd3bd02c5ee0522b6973ca50 132 ProSitePatterns PS00054 Ribosomal protein S11 signature. 100 122 - T 12-10-2018 IPR018102 Ribosomal S11, conserved site MIM_c38960 d3237c1bdd3bd02c5ee0522b6973ca50 132 PIRSF PIRSF002131 2 132 1.5E-51 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MIM_c38960 d3237c1bdd3bd02c5ee0522b6973ca50 132 Pfam PF00411 Ribosomal protein S11 22 131 4.7E-50 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MIM_c04130 e3551a1e5071e7843c91c603962fe9ab 320 SUPERFAMILY SSF53850 41 280 9.58E-15 T 12-10-2018 MIM_c04130 e3551a1e5071e7843c91c603962fe9ab 320 Gene3D G3DSA:3.40.190.10 125 244 3.2E-74 T 12-10-2018 MIM_c04130 e3551a1e5071e7843c91c603962fe9ab 320 Gene3D G3DSA:3.40.190.150 29 306 3.2E-74 T 12-10-2018 MIM_c04130 e3551a1e5071e7843c91c603962fe9ab 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 314 5.0E-48 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c04130 e3551a1e5071e7843c91c603962fe9ab 320 PIRSF PIRSF017082 1 318 9.0E-69 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c34500 277a8fa659d69e975bd47e7237a37fc5 282 SUPERFAMILY SSF103481 179 280 1.24E-6 T 12-10-2018 MIM_c34500 277a8fa659d69e975bd47e7237a37fc5 282 Pfam PF00892 EamA-like transporter family 143 280 5.8E-7 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MIM_c34500 277a8fa659d69e975bd47e7237a37fc5 282 SUPERFAMILY SSF103481 38 138 1.83E-13 T 12-10-2018 MIM_c27040 894d051aa4c0683b562c264057b712f0 569 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 3 569 3.8E-260 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c27040 894d051aa4c0683b562c264057b712f0 569 Gene3D G3DSA:3.20.20.140 132 569 4.4E-274 T 12-10-2018 MIM_c27040 894d051aa4c0683b562c264057b712f0 569 Pfam PF00449 Urease alpha-subunit, N-terminal domain 3 122 2.7E-54 T 12-10-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c27040 894d051aa4c0683b562c264057b712f0 569 SUPERFAMILY SSF51338 1 180 2.68E-59 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MIM_c27040 894d051aa4c0683b562c264057b712f0 569 Pfam PF01979 Amidohydrolase family 128 449 1.6E-57 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MIM_c27040 894d051aa4c0683b562c264057b712f0 569 Gene3D G3DSA:2.30.40.10 4 482 4.4E-274 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MIM_c27040 894d051aa4c0683b562c264057b712f0 569 Hamap MF_01953 Urease subunit alpha [ureC]. 2 569 53.329 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c27040 894d051aa4c0683b562c264057b712f0 569 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 429 442 1.1E-30 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c27040 894d051aa4c0683b562c264057b712f0 569 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 337 353 1.1E-30 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c27040 894d051aa4c0683b562c264057b712f0 569 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 298 315 1.1E-30 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c27040 894d051aa4c0683b562c264057b712f0 569 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 403 418 1.1E-30 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c27040 894d051aa4c0683b562c264057b712f0 569 ProSitePatterns PS01120 Urease nickel ligands signature. 130 143 - T 12-10-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c27040 894d051aa4c0683b562c264057b712f0 569 SUPERFAMILY SSF51556 132 569 1.53E-175 T 12-10-2018 IPR032466 Metal-dependent hydrolase MIM_c02820 50d8410f58e255578b48d5000181d30a 317 Gene3D G3DSA:1.10.3720.10 103 316 5.7E-25 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c02820 50d8410f58e255578b48d5000181d30a 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 130 314 2.4E-32 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c02820 50d8410f58e255578b48d5000181d30a 317 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 37 89 6.0E-12 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MIM_c02820 50d8410f58e255578b48d5000181d30a 317 SUPERFAMILY SSF161098 108 297 4.84E-30 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c37340 9858be4ce04ea2741e6a7e5659aabaea 316 SUPERFAMILY SSF49493 210 294 8.5E-19 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MIM_c37340 9858be4ce04ea2741e6a7e5659aabaea 316 PRINTS PR00625 DnaJ domain signature 41 61 7.1E-23 T 12-10-2018 IPR001623 DnaJ domain MIM_c37340 9858be4ce04ea2741e6a7e5659aabaea 316 PRINTS PR00625 DnaJ domain signature 7 25 7.1E-23 T 12-10-2018 IPR001623 DnaJ domain MIM_c37340 9858be4ce04ea2741e6a7e5659aabaea 316 PRINTS PR00625 DnaJ domain signature 25 40 7.1E-23 T 12-10-2018 IPR001623 DnaJ domain MIM_c37340 9858be4ce04ea2741e6a7e5659aabaea 316 PRINTS PR00625 DnaJ domain signature 61 80 7.1E-23 T 12-10-2018 IPR001623 DnaJ domain MIM_c37340 9858be4ce04ea2741e6a7e5659aabaea 316 SUPERFAMILY SSF46565 1 78 1.19E-28 T 12-10-2018 IPR036869 Chaperone J-domain superfamily MIM_c37340 9858be4ce04ea2741e6a7e5659aabaea 316 SMART SM00271 4 61 6.9E-26 T 12-10-2018 IPR001623 DnaJ domain MIM_c37340 9858be4ce04ea2741e6a7e5659aabaea 316 Gene3D G3DSA:2.60.260.20 123 203 9.6E-18 T 12-10-2018 MIM_c37340 9858be4ce04ea2741e6a7e5659aabaea 316 Gene3D G3DSA:1.10.287.110 2 120 1.6E-31 T 12-10-2018 IPR036869 Chaperone J-domain superfamily MIM_c37340 9858be4ce04ea2741e6a7e5659aabaea 316 Pfam PF00226 DnaJ domain 5 66 1.2E-24 T 12-10-2018 IPR001623 DnaJ domain MIM_c37340 9858be4ce04ea2741e6a7e5659aabaea 316 SUPERFAMILY SSF49493 120 211 9.42E-17 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MIM_c37340 9858be4ce04ea2741e6a7e5659aabaea 316 Pfam PF01556 DnaJ C terminal domain 128 283 1.3E-34 T 12-10-2018 IPR002939 Chaperone DnaJ, C-terminal MIM_c37340 9858be4ce04ea2741e6a7e5659aabaea 316 Gene3D G3DSA:2.60.260.20 204 283 1.4E-26 T 12-10-2018 MIM_c37340 9858be4ce04ea2741e6a7e5659aabaea 316 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 12-10-2018 IPR018253 DnaJ domain, conserved site MIM_c12200 2a8cb5f7796264fa0fc8cc7a48e56cf3 450 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 199 448 8.3E-84 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MIM_c12200 2a8cb5f7796264fa0fc8cc7a48e56cf3 450 Gene3D G3DSA:1.10.285.10 386 450 7.4E-8 T 12-10-2018 MIM_c12200 2a8cb5f7796264fa0fc8cc7a48e56cf3 450 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 374 385 3.5E-29 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MIM_c12200 2a8cb5f7796264fa0fc8cc7a48e56cf3 450 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 232 252 3.5E-29 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MIM_c12200 2a8cb5f7796264fa0fc8cc7a48e56cf3 450 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 190 212 3.5E-29 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MIM_c12200 2a8cb5f7796264fa0fc8cc7a48e56cf3 450 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 111 125 3.5E-29 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MIM_c12200 2a8cb5f7796264fa0fc8cc7a48e56cf3 450 Gene3D G3DSA:1.10.285.10 3 385 2.1E-162 T 12-10-2018 MIM_c12200 2a8cb5f7796264fa0fc8cc7a48e56cf3 450 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 54 182 3.5E-50 T 12-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MIM_c12200 2a8cb5f7796264fa0fc8cc7a48e56cf3 450 PIRSF PIRSF000185 19 450 5.7E-115 T 12-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 MIM_c12200 2a8cb5f7796264fa0fc8cc7a48e56cf3 450 SUPERFAMILY SSF53223 2 193 1.82E-72 T 12-10-2018 MIM_c12200 2a8cb5f7796264fa0fc8cc7a48e56cf3 450 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 119 132 - T 12-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MIM_c12200 2a8cb5f7796264fa0fc8cc7a48e56cf3 450 SMART SM00839 201 448 7.9E-85 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MIM_c12200 2a8cb5f7796264fa0fc8cc7a48e56cf3 450 Gene3D G3DSA:3.40.50.720 206 375 2.1E-162 T 12-10-2018 MIM_c12200 2a8cb5f7796264fa0fc8cc7a48e56cf3 450 Gene3D G3DSA:3.40.50.10860 52 187 2.1E-162 T 12-10-2018 MIM_c12200 2a8cb5f7796264fa0fc8cc7a48e56cf3 450 SUPERFAMILY SSF51735 199 448 1.46E-73 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c17620 fb9a2cf0767d0b6e80f51361a78cc566 564 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 8 176 3.5E-43 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MIM_c17620 fb9a2cf0767d0b6e80f51361a78cc566 564 Gene3D G3DSA:3.40.50.970 1 186 7.1E-50 T 12-10-2018 MIM_c17620 fb9a2cf0767d0b6e80f51361a78cc566 564 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 203 329 2.0E-27 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MIM_c17620 fb9a2cf0767d0b6e80f51361a78cc566 564 SUPERFAMILY SSF52467 202 358 1.12E-34 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MIM_c17620 fb9a2cf0767d0b6e80f51361a78cc566 564 Gene3D G3DSA:3.40.50.1220 201 364 1.0E-36 T 12-10-2018 MIM_c17620 fb9a2cf0767d0b6e80f51361a78cc566 564 SUPERFAMILY SSF52518 365 543 7.68E-54 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c17620 fb9a2cf0767d0b6e80f51361a78cc566 564 Gene3D G3DSA:3.40.50.970 365 538 2.7E-52 T 12-10-2018 MIM_c17620 fb9a2cf0767d0b6e80f51361a78cc566 564 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 390 530 1.4E-35 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MIM_c17620 fb9a2cf0767d0b6e80f51361a78cc566 564 SUPERFAMILY SSF52518 6 176 5.01E-43 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c20120 58f54b82b2c1594e3d0e1425d95d9597 327 Gene3D G3DSA:3.40.190.10 128 251 1.3E-91 T 12-10-2018 MIM_c20120 58f54b82b2c1594e3d0e1425d95d9597 327 SUPERFAMILY SSF53850 124 282 7.01E-12 T 12-10-2018 MIM_c20120 58f54b82b2c1594e3d0e1425d95d9597 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 324 8.7E-74 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c20120 58f54b82b2c1594e3d0e1425d95d9597 327 Gene3D G3DSA:3.40.190.150 31 317 1.3E-91 T 12-10-2018 MIM_c20120 58f54b82b2c1594e3d0e1425d95d9597 327 PIRSF PIRSF017082 1 326 5.3E-73 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c23800 d5f14bbc76c7c1ea9bf952ac13c9c21d 313 Hamap MF_00367 GTPase Era [era]. 23 312 33.341 T 12-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c23800 d5f14bbc76c7c1ea9bf952ac13c9c21d 313 SUPERFAMILY SSF54814 198 313 1.37E-37 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 MIM_c23800 d5f14bbc76c7c1ea9bf952ac13c9c21d 313 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 24 186 3.2E-25 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MIM_c23800 d5f14bbc76c7c1ea9bf952ac13c9c21d 313 TIGRFAM TIGR00436 era: GTP-binding protein Era 26 295 7.6E-79 T 12-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c23800 d5f14bbc76c7c1ea9bf952ac13c9c21d 313 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 28 48 7.3E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 MIM_c23800 d5f14bbc76c7c1ea9bf952ac13c9c21d 313 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 96 114 7.3E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 MIM_c23800 d5f14bbc76c7c1ea9bf952ac13c9c21d 313 Gene3D G3DSA:3.40.50.300 24 200 3.6E-44 T 12-10-2018 MIM_c23800 d5f14bbc76c7c1ea9bf952ac13c9c21d 313 Pfam PF01926 50S ribosome-binding GTPase 28 139 1.7E-23 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 MIM_c23800 d5f14bbc76c7c1ea9bf952ac13c9c21d 313 Gene3D G3DSA:3.30.300.20 202 313 2.4E-37 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta MIM_c23800 d5f14bbc76c7c1ea9bf952ac13c9c21d 313 Pfam PF07650 KH domain 225 300 6.1E-15 T 12-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c23800 d5f14bbc76c7c1ea9bf952ac13c9c21d 313 SUPERFAMILY SSF52540 28 219 7.09E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c15710 3145ddb073218f1de8ee35dd8ad900ad 228 SMART SM00862 145 218 2.0E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MIM_c15710 3145ddb073218f1de8ee35dd8ad900ad 228 SUPERFAMILY SSF46894 118 220 1.13E-25 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MIM_c15710 3145ddb073218f1de8ee35dd8ad900ad 228 Gene3D G3DSA:1.10.10.10 123 225 7.2E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c15710 3145ddb073218f1de8ee35dd8ad900ad 228 SMART SM00448 1 112 2.8E-42 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c15710 3145ddb073218f1de8ee35dd8ad900ad 228 SUPERFAMILY SSF52172 1 133 1.02E-38 T 12-10-2018 IPR011006 CheY-like superfamily MIM_c15710 3145ddb073218f1de8ee35dd8ad900ad 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 218 1.3E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MIM_c15710 3145ddb073218f1de8ee35dd8ad900ad 228 Gene3D G3DSA:3.40.50.2300 1 122 3.3E-39 T 12-10-2018 MIM_c15710 3145ddb073218f1de8ee35dd8ad900ad 228 Pfam PF00072 Response regulator receiver domain 3 112 9.2E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c10150 a309d854342b228a91620834d1df368c 350 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 262 340 4.0E-33 T 12-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 MIM_c10150 a309d854342b228a91620834d1df368c 350 SUPERFAMILY SSF46785 268 342 5.94E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c10150 a309d854342b228a91620834d1df368c 350 SMART SM00382 63 191 2.0E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c10150 a309d854342b228a91620834d1df368c 350 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 35 338 2.6E-147 T 12-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 MIM_c10150 a309d854342b228a91620834d1df368c 350 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 21 247 2.3E-118 T 12-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 MIM_c10150 a309d854342b228a91620834d1df368c 350 Gene3D G3DSA:1.10.10.10 269 347 2.8E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c10150 a309d854342b228a91620834d1df368c 350 Gene3D G3DSA:1.10.8.60 194 268 1.6E-30 T 12-10-2018 MIM_c10150 a309d854342b228a91620834d1df368c 350 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 350 179.834 T 12-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 MIM_c10150 a309d854342b228a91620834d1df368c 350 Gene3D G3DSA:3.40.50.300 30 193 6.0E-41 T 12-10-2018 MIM_c10150 a309d854342b228a91620834d1df368c 350 SUPERFAMILY SSF52540 32 262 3.07E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c10150 a309d854342b228a91620834d1df368c 350 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 265 338 1.3E-32 T 12-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 MIM_c10150 a309d854342b228a91620834d1df368c 350 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 71 90 2.8E-6 T 12-10-2018 MIM_c10150 a309d854342b228a91620834d1df368c 350 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 340 350 2.8E-6 T 12-10-2018 MIM_c04900 d03049c23b0a4b1f2cf14ee03c2e3a02 130 SUPERFAMILY SSF141734 3 110 2.62E-48 T 12-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 MIM_c04900 d03049c23b0a4b1f2cf14ee03c2e3a02 130 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 3 107 32.493 T 12-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 MIM_c04900 d03049c23b0a4b1f2cf14ee03c2e3a02 130 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 29 103 3.7E-35 T 12-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 MIM_c04900 d03049c23b0a4b1f2cf14ee03c2e3a02 130 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 52 106 3.0E-18 T 12-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 MIM_c04900 d03049c23b0a4b1f2cf14ee03c2e3a02 130 Gene3D G3DSA:3.10.20.400 2 94 6.7E-39 T 12-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 MIM_c21670 ca78597dbb7b3f6954c52c41b5c2e334 238 Pfam PF02230 Phospholipase/Carboxylesterase 84 211 4.2E-5 T 12-10-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 MIM_c21670 ca78597dbb7b3f6954c52c41b5c2e334 238 Gene3D G3DSA:3.40.50.1820 2 198 5.0E-7 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c36980 bb2f365a84f8d1d54c18f859eddf7c39 302 Gene3D G3DSA:3.50.50.60 126 230 3.5E-44 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c36980 bb2f365a84f8d1d54c18f859eddf7c39 302 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 7 29 4.5E-16 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MIM_c36980 bb2f365a84f8d1d54c18f859eddf7c39 302 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 152 176 4.5E-16 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MIM_c36980 bb2f365a84f8d1d54c18f859eddf7c39 302 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 115 123 4.5E-16 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MIM_c36980 bb2f365a84f8d1d54c18f859eddf7c39 302 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 279 7.3E-23 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MIM_c36980 bb2f365a84f8d1d54c18f859eddf7c39 302 SUPERFAMILY SSF51905 4 297 1.41E-37 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c36980 bb2f365a84f8d1d54c18f859eddf7c39 302 Gene3D G3DSA:3.50.50.60 6 290 3.5E-44 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c36980 bb2f365a84f8d1d54c18f859eddf7c39 302 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 114 132 3.2E-21 T 12-10-2018 MIM_c36980 bb2f365a84f8d1d54c18f859eddf7c39 302 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 3.2E-21 T 12-10-2018 MIM_c36980 bb2f365a84f8d1d54c18f859eddf7c39 302 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 3.2E-21 T 12-10-2018 MIM_c36980 bb2f365a84f8d1d54c18f859eddf7c39 302 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 250 272 3.2E-21 T 12-10-2018 MIM_c36980 bb2f365a84f8d1d54c18f859eddf7c39 302 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 222 238 3.2E-21 T 12-10-2018 MIM_c11890 4a3b14339afeef85642df2850f23f1b6 338 SUPERFAMILY SSF51735 1 182 4.85E-74 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c11890 4a3b14339afeef85642df2850f23f1b6 338 SUPERFAMILY SSF48179 183 333 6.63E-70 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c11890 4a3b14339afeef85642df2850f23f1b6 338 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 326 7.8E-135 T 12-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MIM_c11890 4a3b14339afeef85642df2850f23f1b6 338 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 328 44.919 T 12-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MIM_c11890 4a3b14339afeef85642df2850f23f1b6 338 Gene3D G3DSA:3.40.50.720 1 182 9.8E-77 T 12-10-2018 MIM_c11890 4a3b14339afeef85642df2850f23f1b6 338 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 326 3.3E-64 T 12-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MIM_c11890 4a3b14339afeef85642df2850f23f1b6 338 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 177 4.2E-74 T 12-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MIM_c11890 4a3b14339afeef85642df2850f23f1b6 338 PIRSF PIRSF000116 201 332 2.6E-14 T 12-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MIM_c11890 4a3b14339afeef85642df2850f23f1b6 338 PIRSF PIRSF000116 2 209 1.1E-49 T 12-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MIM_c11890 4a3b14339afeef85642df2850f23f1b6 338 Gene3D G3DSA:1.10.3730.40 183 338 2.6E-73 T 12-10-2018 MIM_c27220 7c3a108382233f38673ee88c4db82775 389 Gene3D G3DSA:3.40.50.2300 144 362 2.1E-114 T 12-10-2018 MIM_c27220 7c3a108382233f38673ee88c4db82775 389 Pfam PF13458 Periplasmic binding protein 26 364 5.1E-74 T 12-10-2018 IPR028081 Leucine-binding protein domain MIM_c27220 7c3a108382233f38673ee88c4db82775 389 SUPERFAMILY SSF53822 26 369 1.14E-86 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c27220 7c3a108382233f38673ee88c4db82775 389 Gene3D G3DSA:3.40.50.2300 28 356 2.1E-114 T 12-10-2018 MIM_c19370 95d688694f50756f35772c019cb0f264 255 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 188 205 - T 12-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 MIM_c19370 95d688694f50756f35772c019cb0f264 255 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 15 243 39.911 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MIM_c19370 95d688694f50756f35772c019cb0f264 255 Pfam PF01255 Putative undecaprenyl diphosphate synthase 22 242 5.6E-79 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MIM_c19370 95d688694f50756f35772c019cb0f264 255 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 15 242 4.4E-92 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MIM_c19370 95d688694f50756f35772c019cb0f264 255 Gene3D G3DSA:3.40.1180.10 3 246 2.2E-91 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 MIM_c19370 95d688694f50756f35772c019cb0f264 255 SUPERFAMILY SSF64005 12 238 2.49E-87 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 MIM_c06360 c90ca911dd17d4e97755799a7b8cb5dd 335 PIRSF PIRSF500176 8 332 1.3E-73 T 12-10-2018 MIM_c06360 c90ca911dd17d4e97755799a7b8cb5dd 335 Gene3D G3DSA:3.40.50.1170 8 211 9.4E-62 T 12-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 MIM_c06360 c90ca911dd17d4e97755799a7b8cb5dd 335 SUPERFAMILY SSF53774 8 330 7.59E-82 T 12-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 MIM_c06360 c90ca911dd17d4e97755799a7b8cb5dd 335 Pfam PF00710 Asparaginase, N-terminal 14 200 1.2E-47 T 12-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 MIM_c06360 c90ca911dd17d4e97755799a7b8cb5dd 335 PRINTS PR00139 Asparaginase/glutaminase family signature 88 106 2.2E-10 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c06360 c90ca911dd17d4e97755799a7b8cb5dd 335 PRINTS PR00139 Asparaginase/glutaminase family signature 12 23 2.2E-10 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c06360 c90ca911dd17d4e97755799a7b8cb5dd 335 PRINTS PR00139 Asparaginase/glutaminase family signature 261 279 2.2E-10 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c06360 c90ca911dd17d4e97755799a7b8cb5dd 335 Gene3D G3DSA:3.40.50.40 215 330 9.2E-26 T 12-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 MIM_c06360 c90ca911dd17d4e97755799a7b8cb5dd 335 PIRSF PIRSF001220 7 335 3.5E-81 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c06360 c90ca911dd17d4e97755799a7b8cb5dd 335 SMART SM00870 11 327 8.7E-100 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c09450 f43aec839dd04dfb67f6fd75886aded0 908 Gene3D G3DSA:1.10.10.1100 853 904 4.4E-10 T 12-10-2018 MIM_c09450 f43aec839dd04dfb67f6fd75886aded0 908 PIRSF PIRSF036643 7 735 1.3E-160 T 12-10-2018 MIM_c09450 f43aec839dd04dfb67f6fd75886aded0 908 Gene3D G3DSA:3.40.228.10 155 356 1.4E-178 T 12-10-2018 MIM_c09450 f43aec839dd04dfb67f6fd75886aded0 908 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 18 67 1.8E-15 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c09450 f43aec839dd04dfb67f6fd75886aded0 908 SUPERFAMILY SSF53706 16 599 1.31E-186 T 12-10-2018 MIM_c09450 f43aec839dd04dfb67f6fd75886aded0 908 SUPERFAMILY SSF50692 565 713 4.29E-38 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily MIM_c09450 f43aec839dd04dfb67f6fd75886aded0 908 Gene3D G3DSA:3.40.50.740 84 558 1.4E-178 T 12-10-2018 MIM_c09450 f43aec839dd04dfb67f6fd75886aded0 908 Pfam PF04324 BFD-like [2Fe-2S] binding domain 853 900 1.6E-9 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain MIM_c09450 f43aec839dd04dfb67f6fd75886aded0 908 Gene3D G3DSA:2.20.25.90 14 71 7.0E-15 T 12-10-2018 MIM_c09450 f43aec839dd04dfb67f6fd75886aded0 908 Pfam PF00384 Molybdopterin oxidoreductase 83 503 6.0E-79 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c09450 f43aec839dd04dfb67f6fd75886aded0 908 Gene3D G3DSA:2.40.40.20 590 715 1.5E-37 T 12-10-2018 MIM_c09450 f43aec839dd04dfb67f6fd75886aded0 908 SMART SM00926 17 71 5.3E-15 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c09450 f43aec839dd04dfb67f6fd75886aded0 908 Pfam PF01568 Molydopterin dinucleotide binding domain 599 709 2.8E-26 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 MIM_c09450 f43aec839dd04dfb67f6fd75886aded0 908 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 22 40 - T 12-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 MIM_c09730 87fec2425ddc4f72513ae8cbd4fd72fa 389 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 68 80 1.9E-5 T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c09730 87fec2425ddc4f72513ae8cbd4fd72fa 389 Pfam PF00953 Glycosyl transferase family 4 99 307 3.4E-35 T 12-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 MIM_c09730 87fec2425ddc4f72513ae8cbd4fd72fa 389 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 387 23.299 T 12-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c09730 87fec2425ddc4f72513ae8cbd4fd72fa 389 ProSitePatterns PS01348 MraY family signature 2. 212 223 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c09730 87fec2425ddc4f72513ae8cbd4fd72fa 389 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 38 389 6.5E-121 T 12-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c09730 87fec2425ddc4f72513ae8cbd4fd72fa 389 ProSitePatterns PS01347 MraY family signature 1. 68 80 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c13560 317f9afe677fae94550a89d97c9fdfe2 400 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 17 380 2.3E-140 T 12-10-2018 IPR007434 Peptidogalycan biosysnthesis/recognition MIM_c13560 317f9afe677fae94550a89d97c9fdfe2 400 SUPERFAMILY SSF55729 182 350 3.22E-34 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c11970 dcc2bab14e120169f8c239724c69b601 327 SUPERFAMILY SSF53850 116 298 5.07E-14 T 12-10-2018 MIM_c11970 dcc2bab14e120169f8c239724c69b601 327 Gene3D G3DSA:3.40.190.10 131 253 1.4E-88 T 12-10-2018 MIM_c11970 dcc2bab14e120169f8c239724c69b601 327 Gene3D G3DSA:3.40.190.150 35 313 1.4E-88 T 12-10-2018 MIM_c11970 dcc2bab14e120169f8c239724c69b601 327 PIRSF PIRSF017082 5 327 1.4E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c11970 dcc2bab14e120169f8c239724c69b601 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 55 323 3.8E-95 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c02550 0062697720717e2c85e59e9cda26a04d 340 Gene3D G3DSA:3.40.190.150 45 330 3.5E-112 T 12-10-2018 MIM_c02550 0062697720717e2c85e59e9cda26a04d 340 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 65 337 5.4E-85 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c02550 0062697720717e2c85e59e9cda26a04d 340 SUPERFAMILY SSF53850 126 300 5.35E-18 T 12-10-2018 MIM_c02550 0062697720717e2c85e59e9cda26a04d 340 PIRSF PIRSF017082 11 340 1.5E-81 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c02550 0062697720717e2c85e59e9cda26a04d 340 Gene3D G3DSA:3.40.190.10 142 265 3.5E-112 T 12-10-2018 MIM_c33370 0d2ea3c12c94a5f7c4cfa2e9e411021e 52 SUPERFAMILY SSF48295 1 42 5.23E-7 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 MIM_c34570 f73f6203f3d8e18fea454107db8ae7f5 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 260 2.4E-12 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c34570 f73f6203f3d8e18fea454107db8ae7f5 285 SUPERFAMILY SSF161098 8 270 2.34E-44 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c34570 f73f6203f3d8e18fea454107db8ae7f5 285 Gene3D G3DSA:1.10.3720.10 10 275 2.8E-41 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c04880 c512f4ab37deb52b0727b2763bb473d8 250 Gene3D G3DSA:3.20.20.70 1 242 2.9E-87 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c04880 c512f4ab37deb52b0727b2763bb473d8 250 Pfam PF00977 Histidine biosynthesis protein 3 232 1.3E-79 T 12-10-2018 IPR006062 Histidine biosynthesis GO:0000105 MIM_c04880 c512f4ab37deb52b0727b2763bb473d8 250 SUPERFAMILY SSF51366 1 239 3.69E-74 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MIM_c04880 c512f4ab37deb52b0727b2763bb473d8 250 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 236 7.1E-78 T 12-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 MIM_c04880 c512f4ab37deb52b0727b2763bb473d8 250 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 240 36.749 T 12-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 MIM_c21640 7fd4fbff42713af5be87121b3a1ab095 486 PIRSF PIRSF000130 1 486 8.8E-204 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 MIM_c21640 7fd4fbff42713af5be87121b3a1ab095 486 Pfam PF00571 CBS domain 95 138 2.4E-10 T 12-10-2018 IPR000644 CBS domain MIM_c21640 7fd4fbff42713af5be87121b3a1ab095 486 Pfam PF00571 CBS domain 149 201 1.9E-4 T 12-10-2018 IPR000644 CBS domain MIM_c21640 7fd4fbff42713af5be87121b3a1ab095 486 SUPERFAMILY SSF51412 2 476 9.68E-127 T 12-10-2018 MIM_c21640 7fd4fbff42713af5be87121b3a1ab095 486 SMART SM01240 6 472 0.0 T 12-10-2018 MIM_c21640 7fd4fbff42713af5be87121b3a1ab095 486 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 7 472 1.4E-164 T 12-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 MIM_c21640 7fd4fbff42713af5be87121b3a1ab095 486 SMART SM00116 156 204 2.0E-5 T 12-10-2018 IPR000644 CBS domain MIM_c21640 7fd4fbff42713af5be87121b3a1ab095 486 SMART SM00116 95 142 1.4E-10 T 12-10-2018 IPR000644 CBS domain MIM_c21640 7fd4fbff42713af5be87121b3a1ab095 486 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 7 485 86.548 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 MIM_c21640 7fd4fbff42713af5be87121b3a1ab095 486 SUPERFAMILY SSF54631 94 201 4.27E-27 T 12-10-2018 MIM_c21640 7fd4fbff42713af5be87121b3a1ab095 486 Gene3D G3DSA:3.20.20.70 1 485 3.7E-213 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c21640 7fd4fbff42713af5be87121b3a1ab095 486 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 7 453 4.9E-191 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 MIM_c21640 7fd4fbff42713af5be87121b3a1ab095 486 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 293 305 - T 12-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 MIM_c27960 e5b35269a489eabee800a32a23c9b69d 631 SUPERFAMILY SSF82866 409 608 9.42E-41 T 12-10-2018 MIM_c27960 e5b35269a489eabee800a32a23c9b69d 631 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 358 592 1.3E-71 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MIM_c27960 e5b35269a489eabee800a32a23c9b69d 631 Pfam PF02355 Protein export membrane protein 432 595 2.1E-19 T 12-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial MIM_c27960 e5b35269a489eabee800a32a23c9b69d 631 Gene3D G3DSA:3.30.1360.200 289 430 1.0E-52 T 12-10-2018 MIM_c27960 e5b35269a489eabee800a32a23c9b69d 631 Gene3D G3DSA:1.20.1640.10 433 612 2.9E-10 T 12-10-2018 MIM_c27960 e5b35269a489eabee800a32a23c9b69d 631 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 132 598 1.2E-138 T 12-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 MIM_c27960 e5b35269a489eabee800a32a23c9b69d 631 Pfam PF07549 SecD/SecF GG Motif 124 149 9.0E-7 T 12-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site MIM_c27960 e5b35269a489eabee800a32a23c9b69d 631 Gene3D G3DSA:3.30.70.3400 229 432 1.0E-52 T 12-10-2018 MIM_c27960 e5b35269a489eabee800a32a23c9b69d 631 Pfam PF13721 SecD export protein N-terminal TM region 1 112 4.3E-35 T 12-10-2018 IPR027398 SecD export protein N-terminal TM domain MIM_c27960 e5b35269a489eabee800a32a23c9b69d 631 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 614 45.342 T 12-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 MIM_c38220 9fc2103b1826ebc84cca93189f2ff8c4 293 SUPERFAMILY SSF103481 188 288 2.35E-8 T 12-10-2018 MIM_c38220 9fc2103b1826ebc84cca93189f2ff8c4 293 Pfam PF00892 EamA-like transporter family 13 136 4.2E-13 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MIM_c38220 9fc2103b1826ebc84cca93189f2ff8c4 293 Pfam PF00892 EamA-like transporter family 154 286 6.7E-14 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MIM_c38220 9fc2103b1826ebc84cca93189f2ff8c4 293 SUPERFAMILY SSF103481 49 136 1.7E-8 T 12-10-2018 MIM_c18870 560c95d39272c8fd599faa403a03cf28 211 ProSitePatterns PS00856 Guanylate kinase-like signature. 40 57 - T 12-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 MIM_c18870 560c95d39272c8fd599faa403a03cf28 211 SUPERFAMILY SSF52540 3 191 9.96E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c18870 560c95d39272c8fd599faa403a03cf28 211 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 6 184 1.2E-70 T 12-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 MIM_c18870 560c95d39272c8fd599faa403a03cf28 211 SMART SM00072 5 187 9.4E-60 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit MIM_c18870 560c95d39272c8fd599faa403a03cf28 211 Gene3D G3DSA:3.30.63.10 37 96 3.3E-63 T 12-10-2018 MIM_c18870 560c95d39272c8fd599faa403a03cf28 211 Pfam PF00625 Guanylate kinase 9 185 3.3E-46 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit MIM_c18870 560c95d39272c8fd599faa403a03cf28 211 Hamap MF_00328 Guanylate kinase [gmk]. 4 187 35.46 T 12-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 MIM_c18870 560c95d39272c8fd599faa403a03cf28 211 Gene3D G3DSA:3.40.50.300 10 183 3.3E-63 T 12-10-2018 MIM_c35540 93c6cbb23b7a50e2dbc40738d5d08127 147 SUPERFAMILY SSF54427 36 134 8.49E-35 T 12-10-2018 IPR032710 NTF2-like domain superfamily MIM_c35540 93c6cbb23b7a50e2dbc40738d5d08127 147 Gene3D G3DSA:3.10.450.50 11 136 7.0E-38 T 12-10-2018 MIM_c35540 93c6cbb23b7a50e2dbc40738d5d08127 147 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 9 133 28.182 T 12-10-2018 IPR023006 Uncharacterised protein family UPF0225 MIM_c08530 3d1216a2b3f12da33a5a64103fc57934 170 SMART SM00347 42 142 4.6E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c08530 3d1216a2b3f12da33a5a64103fc57934 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 132 152 9.2E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c08530 3d1216a2b3f12da33a5a64103fc57934 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 102 118 9.2E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c08530 3d1216a2b3f12da33a5a64103fc57934 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 82 9.2E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c08530 3d1216a2b3f12da33a5a64103fc57934 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 98 9.2E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c08530 3d1216a2b3f12da33a5a64103fc57934 170 Gene3D G3DSA:1.10.10.10 8 154 1.4E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c08530 3d1216a2b3f12da33a5a64103fc57934 170 Pfam PF12802 MarR family 48 106 2.5E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c08530 3d1216a2b3f12da33a5a64103fc57934 170 SUPERFAMILY SSF46785 23 153 2.55E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c40150 48f5e231271460bb68a816062711740d 325 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 1.6E-14 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c40150 48f5e231271460bb68a816062711740d 325 SUPERFAMILY SSF46785 3 115 1.82E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c40150 48f5e231271460bb68a816062711740d 325 Gene3D G3DSA:3.40.190.290 94 307 1.4E-36 T 12-10-2018 MIM_c40150 48f5e231271460bb68a816062711740d 325 Pfam PF03466 LysR substrate binding domain 91 300 7.6E-38 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c40150 48f5e231271460bb68a816062711740d 325 SUPERFAMILY SSF53850 92 301 1.09E-39 T 12-10-2018 MIM_c40150 48f5e231271460bb68a816062711740d 325 Gene3D G3DSA:1.10.10.10 5 92 2.3E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c27370 c928829e349e073de11d3ae4fd46893b 497 Gene3D G3DSA:3.40.605.10 26 460 2.0E-143 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c27370 c928829e349e073de11d3ae4fd46893b 497 Pfam PF00171 Aldehyde dehydrogenase family 17 479 4.8E-136 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c27370 c928829e349e073de11d3ae4fd46893b 497 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 8 483 2.4E-208 T 12-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 MIM_c27370 c928829e349e073de11d3ae4fd46893b 497 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MIM_c27370 c928829e349e073de11d3ae4fd46893b 497 SUPERFAMILY SSF53720 4 484 3.93E-145 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c27370 c928829e349e073de11d3ae4fd46893b 497 Gene3D G3DSA:3.40.309.10 252 452 2.0E-143 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MIM_c15250 09da5a16905e8e2a8f89a848e982a981 585 SUPERFAMILY SSF90123 15 328 3.4E-72 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MIM_c15250 09da5a16905e8e2a8f89a848e982a981 585 Gene3D G3DSA:3.40.50.300 331 583 2.1E-91 T 12-10-2018 MIM_c15250 09da5a16905e8e2a8f89a848e982a981 585 Pfam PF00664 ABC transporter transmembrane region 30 299 7.5E-51 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MIM_c15250 09da5a16905e8e2a8f89a848e982a981 585 SUPERFAMILY SSF52540 341 582 1.11E-91 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c15250 09da5a16905e8e2a8f89a848e982a981 585 TIGRFAM TIGR02203 MsbA_lipidA: lipid A export permease/ATP-binding protein MsbA 14 584 3.2E-242 T 12-10-2018 IPR011917 ABC transporter, lipid A export, MsbA GO:0005524|GO:0016021|GO:0034040 MIM_c15250 09da5a16905e8e2a8f89a848e982a981 585 SMART SM00382 370 557 2.5E-19 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c15250 09da5a16905e8e2a8f89a848e982a981 585 ProSitePatterns PS00211 ABC transporters family signature. 483 497 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c15250 09da5a16905e8e2a8f89a848e982a981 585 Pfam PF00005 ABC transporter 361 511 1.2E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c15250 09da5a16905e8e2a8f89a848e982a981 585 Gene3D G3DSA:1.20.1560.10 3 330 3.4E-76 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MIM_c12000 1b5112b0fbd45e0f59fbffb92fbe291b 322 SUPERFAMILY SSF51412 12 310 4.94E-60 T 12-10-2018 MIM_c12000 1b5112b0fbd45e0f59fbffb92fbe291b 322 Pfam PF03060 Nitronate monooxygenase 76 251 2.4E-22 T 12-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 MIM_c12000 1b5112b0fbd45e0f59fbffb92fbe291b 322 Gene3D G3DSA:3.20.20.70 9 321 1.2E-68 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c38560 18d6f38a1c615b1106371e354e5324c4 308 SUPERFAMILY SSF53850 83 277 2.02E-32 T 12-10-2018 MIM_c38560 18d6f38a1c615b1106371e354e5324c4 308 Gene3D G3DSA:3.40.190.10 90 274 8.0E-27 T 12-10-2018 MIM_c38560 18d6f38a1c615b1106371e354e5324c4 308 Gene3D G3DSA:1.10.10.10 1 83 4.6E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c38560 18d6f38a1c615b1106371e354e5324c4 308 SUPERFAMILY SSF46785 1 110 1.48E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c38560 18d6f38a1c615b1106371e354e5324c4 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c38560 18d6f38a1c615b1106371e354e5324c4 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c38560 18d6f38a1c615b1106371e354e5324c4 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c38560 18d6f38a1c615b1106371e354e5324c4 308 Gene3D G3DSA:3.40.190.10 163 265 8.0E-27 T 12-10-2018 MIM_c38560 18d6f38a1c615b1106371e354e5324c4 308 Pfam PF03466 LysR substrate binding domain 89 279 4.4E-33 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c38560 18d6f38a1c615b1106371e354e5324c4 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 6.1E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c19350 9265c98b9121654bfe7829f8d91bdd37 237 Pfam PF00696 Amino acid kinase family 6 214 1.0E-27 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 MIM_c19350 9265c98b9121654bfe7829f8d91bdd37 237 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 5 236 6.5E-100 T 12-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 MIM_c19350 9265c98b9121654bfe7829f8d91bdd37 237 PIRSF PIRSF005650 1 237 3.5E-92 T 12-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 MIM_c19350 9265c98b9121654bfe7829f8d91bdd37 237 Hamap MF_01220_B Uridylate kinase [pyrH]. 3 236 44.447 T 12-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 MIM_c19350 9265c98b9121654bfe7829f8d91bdd37 237 Gene3D G3DSA:3.40.1160.10 1 237 1.4E-77 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MIM_c19350 9265c98b9121654bfe7829f8d91bdd37 237 SUPERFAMILY SSF53633 3 236 2.75E-71 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MIM_c31150 1c3ea0dab5184f99423b33bdc7ccc4df 438 SUPERFAMILY SSF103473 15 432 2.88E-84 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c31150 1c3ea0dab5184f99423b33bdc7ccc4df 438 Pfam PF07690 Major Facilitator Superfamily 32 381 1.4E-42 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c31150 1c3ea0dab5184f99423b33bdc7ccc4df 438 Gene3D G3DSA:1.20.1250.20 15 436 1.8E-74 T 12-10-2018 MIM_c28460 96c6128454ce3acf31264a233456aab0 84 Pfam PF02597 ThiS family 9 84 2.3E-16 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 MIM_c28460 96c6128454ce3acf31264a233456aab0 84 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 7 84 1.0E-20 T 12-10-2018 MIM_c28460 96c6128454ce3acf31264a233456aab0 84 Gene3D G3DSA:3.10.20.30 7 84 1.6E-22 T 12-10-2018 IPR012675 Beta-grasp domain superfamily MIM_c28460 96c6128454ce3acf31264a233456aab0 84 SUPERFAMILY SSF54285 7 84 1.47E-16 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp MIM_c25920 c62879b443e45a24df9a4ce4f320cc1b 297 Gene3D G3DSA:1.10.3720.10 80 294 9.4E-27 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c25920 c62879b443e45a24df9a4ce4f320cc1b 297 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 32 293 8.8E-84 T 12-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 MIM_c25920 c62879b443e45a24df9a4ce4f320cc1b 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 291 1.2E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c25920 c62879b443e45a24df9a4ce4f320cc1b 297 SUPERFAMILY SSF161098 34 291 4.49E-34 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c01260 9d06b7143fbe1cc647c004114e26a21d 278 Pfam PF07883 Cupin domain 195 260 1.4E-7 T 12-10-2018 IPR013096 Cupin 2, conserved barrel MIM_c01260 9d06b7143fbe1cc647c004114e26a21d 278 Pfam PF07883 Cupin domain 72 141 1.1E-11 T 12-10-2018 IPR013096 Cupin 2, conserved barrel MIM_c01260 9d06b7143fbe1cc647c004114e26a21d 278 SUPERFAMILY SSF51182 20 272 1.48E-83 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c01260 9d06b7143fbe1cc647c004114e26a21d 278 TIGRFAM TIGR03214 ura-cupin: putative allantoin catabolism protein 6 272 8.8E-120 T 12-10-2018 IPR017627 Conserved hypothetical protein CHP03214, putative allantoin-urate catabolism protein KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 MIM_c01260 9d06b7143fbe1cc647c004114e26a21d 278 Gene3D G3DSA:2.60.120.10 27 268 9.1E-109 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c01260 9d06b7143fbe1cc647c004114e26a21d 278 Gene3D G3DSA:2.60.120.10 40 165 9.1E-109 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c35810 98e0ea590aa8fa323db87fcf192f3b2a 241 Gene3D G3DSA:2.60.130.10 1 241 1.0E-103 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 MIM_c35810 98e0ea590aa8fa323db87fcf192f3b2a 241 TIGRFAM TIGR02422 protocat_beta: protocatechuate 3,4-dioxygenase, beta subunit 17 238 4.7E-106 T 12-10-2018 IPR012785 Protocatechuate 3,4-dioxygenase, beta subunit GO:0005506|GO:0018578|GO:0019619|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3|MetaCyc: PWY-6041 MIM_c35810 98e0ea590aa8fa323db87fcf192f3b2a 241 Pfam PF12391 Protocatechuate 3,4-dioxygenase beta subunit N terminal 11 43 8.3E-15 T 12-10-2018 IPR024756 Protocatechuate 3,4-dioxygenase beta subunit, N-terminal KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3|MetaCyc: PWY-6041 MIM_c35810 98e0ea590aa8fa323db87fcf192f3b2a 241 Pfam PF00775 Dioxygenase 47 229 6.7E-48 T 12-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 MIM_c35810 98e0ea590aa8fa323db87fcf192f3b2a 241 SUPERFAMILY SSF49482 9 238 2.22E-73 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 MIM_c35810 98e0ea590aa8fa323db87fcf192f3b2a 241 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 81 109 - T 12-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 MIM_c26860 a0a6bd8eb8ac37e8d76552f473a29574 1898 SMART SM00382 664 951 0.31 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c26860 a0a6bd8eb8ac37e8d76552f473a29574 1898 SMART SM00382 1039 1496 3.2 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c26860 a0a6bd8eb8ac37e8d76552f473a29574 1898 SMART SM00382 1564 1851 1.3 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c26860 a0a6bd8eb8ac37e8d76552f473a29574 1898 ProSitePatterns PS00211 ABC transporters family signature. 1762 1776 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c26860 a0a6bd8eb8ac37e8d76552f473a29574 1898 SUPERFAMILY SSF52540 1546 1855 2.51E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c26860 a0a6bd8eb8ac37e8d76552f473a29574 1898 SUPERFAMILY SSF52540 7 602 3.72E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c26860 a0a6bd8eb8ac37e8d76552f473a29574 1898 Gene3D G3DSA:3.40.50.300 1008 1125 9.1E-24 T 12-10-2018 MIM_c26860 a0a6bd8eb8ac37e8d76552f473a29574 1898 SUPERFAMILY SSF52540 653 958 3.32E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c26860 a0a6bd8eb8ac37e8d76552f473a29574 1898 ProSitePatterns PS00211 ABC transporters family signature. 1419 1433 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c26860 a0a6bd8eb8ac37e8d76552f473a29574 1898 Gene3D G3DSA:1.20.1580.10 723 865 6.8E-129 T 12-10-2018 MIM_c26860 a0a6bd8eb8ac37e8d76552f473a29574 1898 Gene3D G3DSA:1.20.1580.10 1625 1762 7.2E-129 T 12-10-2018 MIM_c26860 a0a6bd8eb8ac37e8d76552f473a29574 1898 Gene3D G3DSA:1.10.8.280 297 405 1.5E-222 T 12-10-2018 MIM_c26860 a0a6bd8eb8ac37e8d76552f473a29574 1898 Gene3D G3DSA:3.40.50.300 648 981 6.8E-129 T 12-10-2018 MIM_c26860 a0a6bd8eb8ac37e8d76552f473a29574 1898 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 969 4.9E-297 T 12-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 MIM_c26860 a0a6bd8eb8ac37e8d76552f473a29574 1898 SUPERFAMILY SSF52540 1026 1501 1.17E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c26860 a0a6bd8eb8ac37e8d76552f473a29574 1898 Gene3D G3DSA:3.40.50.300 1545 1882 7.2E-129 T 12-10-2018 MIM_c26860 a0a6bd8eb8ac37e8d76552f473a29574 1898 Gene3D G3DSA:3.30.190.20 131 247 1.5E-222 T 12-10-2018 MIM_c26860 a0a6bd8eb8ac37e8d76552f473a29574 1898 Gene3D G3DSA:3.40.50.300 1259 1529 7.1E-61 T 12-10-2018 MIM_c26860 a0a6bd8eb8ac37e8d76552f473a29574 1898 Gene3D G3DSA:3.30.190.20 1141 1258 8.0E-28 T 12-10-2018 MIM_c26860 a0a6bd8eb8ac37e8d76552f473a29574 1898 Gene3D G3DSA:1.20.1580.10 91 525 1.5E-222 T 12-10-2018 MIM_c26860 a0a6bd8eb8ac37e8d76552f473a29574 1898 Gene3D G3DSA:3.40.50.300 7 626 1.5E-222 T 12-10-2018 MIM_c20620 5617c036c3e6bae80b2518987fc9ebdc 405 Gene3D G3DSA:3.40.50.2300 55 360 5.5E-107 T 12-10-2018 MIM_c20620 5617c036c3e6bae80b2518987fc9ebdc 405 SUPERFAMILY SSF53822 30 402 6.73E-86 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c20620 5617c036c3e6bae80b2518987fc9ebdc 405 Pfam PF13458 Periplasmic binding protein 30 367 7.1E-82 T 12-10-2018 IPR028081 Leucine-binding protein domain MIM_c20620 5617c036c3e6bae80b2518987fc9ebdc 405 Gene3D G3DSA:3.40.50.2300 150 368 5.5E-107 T 12-10-2018 MIM_c13220 383001bdd13e31b9105a7ade9319b750 251 SMART SM00866 103 245 4.0E-27 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MIM_c13220 383001bdd13e31b9105a7ade9319b750 251 SUPERFAMILY SSF64288 71 248 3.14E-38 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MIM_c13220 383001bdd13e31b9105a7ade9319b750 251 SMART SM00345 23 82 4.6E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c13220 383001bdd13e31b9105a7ade9319b750 251 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 2.5E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c13220 383001bdd13e31b9105a7ade9319b750 251 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 2.5E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c13220 383001bdd13e31b9105a7ade9319b750 251 SUPERFAMILY SSF46785 17 86 5.46E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c13220 383001bdd13e31b9105a7ade9319b750 251 Gene3D G3DSA:3.40.1410.10 90 250 2.4E-51 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MIM_c13220 383001bdd13e31b9105a7ade9319b750 251 Gene3D G3DSA:1.10.10.10 15 83 3.1E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c13220 383001bdd13e31b9105a7ade9319b750 251 Pfam PF07702 UTRA domain 107 244 2.6E-29 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MIM_c13220 383001bdd13e31b9105a7ade9319b750 251 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 82 3.9E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c19170 9cd8d0816ad12a21f2bc52ddbba72d2f 287 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 1.6E-37 T 12-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MIM_c19170 9cd8d0816ad12a21f2bc52ddbba72d2f 287 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 259 267 - T 12-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MIM_c19170 9cd8d0816ad12a21f2bc52ddbba72d2f 287 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 75 100 - T 12-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MIM_c19170 9cd8d0816ad12a21f2bc52ddbba72d2f 287 Gene3D G3DSA:3.40.50.10860 8 275 6.5E-111 T 12-10-2018 MIM_c19170 9cd8d0816ad12a21f2bc52ddbba72d2f 287 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 281 2.2E-70 T 12-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MIM_c19170 9cd8d0816ad12a21f2bc52ddbba72d2f 287 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 38.227 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MIM_c19170 9cd8d0816ad12a21f2bc52ddbba72d2f 287 SUPERFAMILY SSF53223 1 121 3.84E-38 T 12-10-2018 MIM_c19170 9cd8d0816ad12a21f2bc52ddbba72d2f 287 SUPERFAMILY SSF51735 122 279 2.23E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c19170 9cd8d0816ad12a21f2bc52ddbba72d2f 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 8.6E-81 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MIM_c19170 9cd8d0816ad12a21f2bc52ddbba72d2f 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 8.6E-81 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MIM_c19170 9cd8d0816ad12a21f2bc52ddbba72d2f 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 8.6E-81 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MIM_c19170 9cd8d0816ad12a21f2bc52ddbba72d2f 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 8.6E-81 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MIM_c19170 9cd8d0816ad12a21f2bc52ddbba72d2f 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 8.6E-81 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MIM_c19170 9cd8d0816ad12a21f2bc52ddbba72d2f 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 8.6E-81 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MIM_c19170 9cd8d0816ad12a21f2bc52ddbba72d2f 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 8.6E-81 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MIM_c19170 9cd8d0816ad12a21f2bc52ddbba72d2f 287 Gene3D G3DSA:3.40.50.720 6 258 6.5E-111 T 12-10-2018 MIM_c24040 9432be60c28903a4eff19c10465ad02f 1074 Gene3D G3DSA:3.40.1260.20 399 508 3.9E-36 T 12-10-2018 MIM_c24040 9432be60c28903a4eff19c10465ad02f 1074 Pfam PF10150 Ribonuclease E/G family 120 389 6.0E-94 T 12-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 MIM_c24040 9432be60c28903a4eff19c10465ad02f 1074 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 423 8.2E-158 T 12-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 MIM_c24040 9432be60c28903a4eff19c10465ad02f 1074 Gene3D G3DSA:2.40.50.140 31 124 2.4E-29 T 12-10-2018 MIM_c24040 9432be60c28903a4eff19c10465ad02f 1074 SMART SM00316 37 118 1.6E-7 T 12-10-2018 IPR022967 RNA-binding domain, S1 MIM_c24040 9432be60c28903a4eff19c10465ad02f 1074 Hamap MF_00970 Ribonuclease E [rne]. 1 1008 33.892 T 12-10-2018 IPR028878 Ribonuclease E GO:0006396|GO:0008995 MIM_c24040 9432be60c28903a4eff19c10465ad02f 1074 SUPERFAMILY SSF50249 39 124 1.26E-16 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c24040 9432be60c28903a4eff19c10465ad02f 1074 Pfam PF00575 S1 RNA binding domain 36 117 4.2E-8 T 12-10-2018 IPR003029 S1 domain GO:0003676 MIM_c29380 e774220429a2db5f28219457f659f501 182 Pfam PF02325 YGGT family 109 176 6.1E-17 T 12-10-2018 IPR003425 CCB3/YggT GO:0016020 MIM_c29380 e774220429a2db5f28219457f659f501 182 Pfam PF02325 YGGT family 12 80 8.3E-12 T 12-10-2018 IPR003425 CCB3/YggT GO:0016020 MIM_c00400 e0a36a30b660a2333b4f993b4259f807 414 Gene3D G3DSA:1.10.540.10 28 134 9.8E-26 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c00400 e0a36a30b660a2333b4f993b4259f807 414 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 255 389 1.7E-17 T 12-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain MIM_c00400 e0a36a30b660a2333b4f993b4259f807 414 Gene3D G3DSA:1.20.140.10 240 412 2.5E-53 T 12-10-2018 MIM_c00400 e0a36a30b660a2333b4f993b4259f807 414 SUPERFAMILY SSF56645 34 237 4.19E-44 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c00400 e0a36a30b660a2333b4f993b4259f807 414 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 31 133 4.2E-13 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c00400 e0a36a30b660a2333b4f993b4259f807 414 PIRSF PIRSF016578 14 406 1.4E-32 T 12-10-2018 MIM_c00400 e0a36a30b660a2333b4f993b4259f807 414 Gene3D G3DSA:2.40.110.10 136 239 6.6E-27 T 12-10-2018 MIM_c00400 e0a36a30b660a2333b4f993b4259f807 414 TIGRFAM TIGR04022 sulfur_SfnB: sulfur acquisition oxidoreductase, SfnB family 22 414 7.0E-175 T 12-10-2018 IPR023922 Sulphate-starvation-induced SfnB MIM_c00400 e0a36a30b660a2333b4f993b4259f807 414 SUPERFAMILY SSF47203 252 412 4.0E-19 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c23140 74b0f423bb312867ab04a35492e3c2d9 229 Gene3D G3DSA:1.20.950.20 1 175 8.2E-18 T 12-10-2018 MIM_c23140 74b0f423bb312867ab04a35492e3c2d9 229 SUPERFAMILY SSF81342 1 191 1.33E-34 T 12-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 MIM_c23140 74b0f423bb312867ab04a35492e3c2d9 229 Pfam PF01292 Prokaryotic cytochrome b561 6 186 2.0E-24 T 12-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 MIM_c11100 d0af1b7f60b76a81b9c9c459598c72ce 409 SMART SM00062 29 253 1.6E-4 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c11100 d0af1b7f60b76a81b9c9c459598c72ce 409 Gene3D G3DSA:3.40.190.10 115 209 1.2E-9 T 12-10-2018 MIM_c11100 d0af1b7f60b76a81b9c9c459598c72ce 409 Gene3D G3DSA:1.10.760.10 285 399 8.7E-12 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c11100 d0af1b7f60b76a81b9c9c459598c72ce 409 SUPERFAMILY SSF53850 44 249 5.23E-15 T 12-10-2018 MIM_c11100 d0af1b7f60b76a81b9c9c459598c72ce 409 Gene3D G3DSA:3.40.190.10 106 249 1.2E-9 T 12-10-2018 MIM_c11100 d0af1b7f60b76a81b9c9c459598c72ce 409 SUPERFAMILY SSF46626 294 388 1.2E-13 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c11100 d0af1b7f60b76a81b9c9c459598c72ce 409 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 304 377 1.3E-8 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c11100 d0af1b7f60b76a81b9c9c459598c72ce 409 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 109 249 1.8E-9 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c23150 a48df9327581e8f53982d8c72a2f2d31 148 Pfam PF01322 Cytochrome C' 29 145 3.8E-33 T 12-10-2018 IPR002321 Cytochrome c, class II GO:0005506|GO:0009055|GO:0020037 MIM_c23150 a48df9327581e8f53982d8c72a2f2d31 148 Gene3D G3DSA:1.20.120.10 22 147 1.8E-39 T 12-10-2018 MIM_c23150 a48df9327581e8f53982d8c72a2f2d31 148 PIRSF PIRSF000027 4 147 2.1E-37 T 12-10-2018 IPR012127 Cytochrome c prime GO:0005506|GO:0009055|GO:0020037|GO:0042597 MIM_c23150 a48df9327581e8f53982d8c72a2f2d31 148 PRINTS PR00608 Class II cytochrome C signature 134 145 9.7E-7 T 12-10-2018 IPR015984 Cytochrome c prime, subgroup MIM_c23150 a48df9327581e8f53982d8c72a2f2d31 148 PRINTS PR00608 Class II cytochrome C signature 111 134 9.7E-7 T 12-10-2018 IPR015984 Cytochrome c prime, subgroup MIM_c23150 a48df9327581e8f53982d8c72a2f2d31 148 SUPERFAMILY SSF47175 23 145 9.86E-36 T 12-10-2018 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 MIM_c23320 3519a6e352e6e88e016adf7e8cd55ff7 427 Gene3D G3DSA:3.30.470.20 189 331 2.3E-54 T 12-10-2018 MIM_c23320 3519a6e352e6e88e016adf7e8cd55ff7 427 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 333 422 4.2E-28 T 12-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MIM_c23320 3519a6e352e6e88e016adf7e8cd55ff7 427 SUPERFAMILY SSF51246 331 424 1.02E-28 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MIM_c23320 3519a6e352e6e88e016adf7e8cd55ff7 427 Gene3D G3DSA:3.30.1490.20 119 188 1.1E-25 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MIM_c23320 3519a6e352e6e88e016adf7e8cd55ff7 427 SUPERFAMILY SSF56059 102 328 3.36E-61 T 12-10-2018 MIM_c23320 3519a6e352e6e88e016adf7e8cd55ff7 427 SUPERFAMILY SSF52440 1 101 8.06E-34 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MIM_c23320 3519a6e352e6e88e016adf7e8cd55ff7 427 SMART SM01210 332 424 2.0E-49 T 12-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MIM_c23320 3519a6e352e6e88e016adf7e8cd55ff7 427 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 424 40.827 T 12-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MIM_c23320 3519a6e352e6e88e016adf7e8cd55ff7 427 SMART SM01209 101 298 7.0E-130 T 12-10-2018 MIM_c23320 3519a6e352e6e88e016adf7e8cd55ff7 427 Gene3D G3DSA:3.40.50.20 1 93 5.6E-34 T 12-10-2018 MIM_c23320 3519a6e352e6e88e016adf7e8cd55ff7 427 Gene3D G3DSA:3.90.600.10 332 427 1.5E-32 T 12-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MIM_c23320 3519a6e352e6e88e016adf7e8cd55ff7 427 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 424 1.2E-160 T 12-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MIM_c23320 3519a6e352e6e88e016adf7e8cd55ff7 427 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 298 9.4E-75 T 12-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MIM_c23320 3519a6e352e6e88e016adf7e8cd55ff7 427 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 4.6E-35 T 12-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MIM_c13780 5ad30f8fe9a9d01414454cfeddf762a8 392 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 218 1.1E-18 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MIM_c13780 5ad30f8fe9a9d01414454cfeddf762a8 392 Gene3D G3DSA:2.40.110.10 124 234 2.2E-25 T 12-10-2018 MIM_c13780 5ad30f8fe9a9d01414454cfeddf762a8 392 PIRSF PIRSF016578 3 221 6.0E-8 T 12-10-2018 MIM_c13780 5ad30f8fe9a9d01414454cfeddf762a8 392 PIRSF PIRSF016578 235 378 2.5E-6 T 12-10-2018 MIM_c13780 5ad30f8fe9a9d01414454cfeddf762a8 392 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 121 1.2E-21 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c13780 5ad30f8fe9a9d01414454cfeddf762a8 392 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 376 8.2E-37 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MIM_c13780 5ad30f8fe9a9d01414454cfeddf762a8 392 SUPERFAMILY SSF56645 6 230 1.96E-54 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c13780 5ad30f8fe9a9d01414454cfeddf762a8 392 Gene3D G3DSA:1.20.140.10 235 383 8.9E-42 T 12-10-2018 MIM_c13780 5ad30f8fe9a9d01414454cfeddf762a8 392 SUPERFAMILY SSF47203 231 378 1.45E-40 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c13780 5ad30f8fe9a9d01414454cfeddf762a8 392 Gene3D G3DSA:1.10.540.10 2 122 5.5E-26 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c33030 bd441d680007db88eed89c22591943e5 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 194 1.4E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c33030 bd441d680007db88eed89c22591943e5 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 104 115 1.4E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c33030 bd441d680007db88eed89c22591943e5 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 165 1.4E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c33030 bd441d680007db88eed89c22591943e5 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 196 213 1.4E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c33030 bd441d680007db88eed89c22591943e5 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 230 250 1.4E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c33030 bd441d680007db88eed89c22591943e5 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 29 46 1.4E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c33030 bd441d680007db88eed89c22591943e5 267 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 34 266 8.9E-58 T 12-10-2018 MIM_c33030 bd441d680007db88eed89c22591943e5 267 SUPERFAMILY SSF51735 29 266 3.08E-72 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c33030 bd441d680007db88eed89c22591943e5 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 175 194 7.2E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c33030 bd441d680007db88eed89c22591943e5 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 104 115 7.2E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c33030 bd441d680007db88eed89c22591943e5 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 163 7.2E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c33030 bd441d680007db88eed89c22591943e5 267 Gene3D G3DSA:3.40.50.720 2 266 8.5E-71 T 12-10-2018 MIM_c28800 62c6bf13ca2a7f1fe0755cd6837ad3a3 291 SUPERFAMILY SSF46785 1 109 3.63E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c28800 62c6bf13ca2a7f1fe0755cd6837ad3a3 291 Gene3D G3DSA:3.40.190.10 89 270 3.3E-30 T 12-10-2018 MIM_c28800 62c6bf13ca2a7f1fe0755cd6837ad3a3 291 SUPERFAMILY SSF53850 88 284 7.91E-34 T 12-10-2018 MIM_c28800 62c6bf13ca2a7f1fe0755cd6837ad3a3 291 Gene3D G3DSA:1.10.10.10 1 88 3.2E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c28800 62c6bf13ca2a7f1fe0755cd6837ad3a3 291 Gene3D G3DSA:3.40.190.10 164 261 3.3E-30 T 12-10-2018 MIM_c28800 62c6bf13ca2a7f1fe0755cd6837ad3a3 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 7.8E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c28800 62c6bf13ca2a7f1fe0755cd6837ad3a3 291 Pfam PF03466 LysR substrate binding domain 86 283 5.1E-34 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c29920 1566d016cc63e4f4faa71747a15d9774 277 Gene3D G3DSA:3.90.79.10 1 158 1.4E-45 T 12-10-2018 MIM_c29920 1566d016cc63e4f4faa71747a15d9774 277 SUPERFAMILY SSF55811 4 159 3.11E-32 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MIM_c29920 1566d016cc63e4f4faa71747a15d9774 277 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MIM_c29920 1566d016cc63e4f4faa71747a15d9774 277 Pfam PF00293 NUDIX domain 7 134 1.0E-24 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MIM_c29920 1566d016cc63e4f4faa71747a15d9774 277 PRINTS PR00502 NUDIX hydrolase family signature 47 62 7.9E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MIM_c29920 1566d016cc63e4f4faa71747a15d9774 277 PRINTS PR00502 NUDIX hydrolase family signature 33 47 7.9E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MIM_c29920 1566d016cc63e4f4faa71747a15d9774 277 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 1 156 37.903 T 12-10-2018 IPR022927 RNA pyrophosphohydrolase RppH MIM_c20720 e00f8677c76231151c35114c4e88bf2a 569 SUPERFAMILY SSF55785 102 197 1.51E-7 T 12-10-2018 IPR035965 PAS domain superfamily MIM_c20720 e00f8677c76231151c35114c4e88bf2a 569 Gene3D G3DSA:3.40.50.300 231 412 2.8E-57 T 12-10-2018 MIM_c20720 e00f8677c76231151c35114c4e88bf2a 569 SMART SM00382 261 405 5.6E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c20720 e00f8677c76231151c35114c4e88bf2a 569 Pfam PF02954 Bacterial regulatory protein, Fis family 526 563 3.2E-11 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MIM_c20720 e00f8677c76231151c35114c4e88bf2a 569 SUPERFAMILY SSF46689 455 566 2.37E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c20720 e00f8677c76231151c35114c4e88bf2a 569 Gene3D G3DSA:3.30.450.20 100 199 1.8E-10 T 12-10-2018 MIM_c20720 e00f8677c76231151c35114c4e88bf2a 569 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 455 464 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site MIM_c20720 e00f8677c76231151c35114c4e88bf2a 569 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 547 567 1.0E-5 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MIM_c20720 e00f8677c76231151c35114c4e88bf2a 569 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 530 547 1.0E-5 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MIM_c20720 e00f8677c76231151c35114c4e88bf2a 569 SUPERFAMILY SSF52540 241 482 7.55E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c20720 e00f8677c76231151c35114c4e88bf2a 569 Gene3D G3DSA:1.10.8.60 413 492 1.1E-20 T 12-10-2018 MIM_c20720 e00f8677c76231151c35114c4e88bf2a 569 Pfam PF00158 Sigma-54 interaction domain 241 408 1.6E-60 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MIM_c20720 e00f8677c76231151c35114c4e88bf2a 569 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 265 278 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MIM_c20720 e00f8677c76231151c35114c4e88bf2a 569 Gene3D G3DSA:1.10.10.60 514 567 5.1E-13 T 12-10-2018 MIM_c10310 64738429892c84f4514533ad4a2a0882 473 Pfam PF00270 DEAD/DEAH box helicase 40 214 3.7E-51 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MIM_c10310 64738429892c84f4514533ad4a2a0882 473 SMART SM00490 276 357 7.3E-33 T 12-10-2018 IPR001650 Helicase, C-terminal MIM_c10310 64738429892c84f4514533ad4a2a0882 473 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 171 179 - T 12-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MIM_c10310 64738429892c84f4514533ad4a2a0882 473 SUPERFAMILY SSF52540 92 378 5.22E-78 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c10310 64738429892c84f4514533ad4a2a0882 473 SMART SM00487 35 240 6.1E-67 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MIM_c10310 64738429892c84f4514533ad4a2a0882 473 Gene3D G3DSA:3.40.50.300 2 228 2.0E-84 T 12-10-2018 MIM_c10310 64738429892c84f4514533ad4a2a0882 473 Pfam PF00271 Helicase conserved C-terminal domain 250 357 7.1E-28 T 12-10-2018 IPR001650 Helicase, C-terminal MIM_c10310 64738429892c84f4514533ad4a2a0882 473 Gene3D G3DSA:3.40.50.300 232 393 2.0E-50 T 12-10-2018 MIM_c12750 276379f54883fb3a8658404e1c0045aa 499 PIRSF PIRSF038928 2 490 3.6E-235 T 12-10-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c12750 276379f54883fb3a8658404e1c0045aa 499 SMART SM01060 13 395 1.8E-272 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c12750 276379f54883fb3a8658404e1c0045aa 499 ProSitePatterns PS00438 Catalase proximal active site signature. 49 65 - T 12-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c12750 276379f54883fb3a8658404e1c0045aa 499 Gene3D G3DSA:2.40.180.10 2 497 5.2E-224 T 12-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 MIM_c12750 276379f54883fb3a8658404e1c0045aa 499 Pfam PF06628 Catalase-related immune-responsive 422 483 1.3E-13 T 12-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c12750 276379f54883fb3a8658404e1c0045aa 499 SUPERFAMILY SSF56634 9 486 3.93E-199 T 12-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c12750 276379f54883fb3a8658404e1c0045aa 499 Pfam PF00199 Catalase 13 391 9.8E-185 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c12750 276379f54883fb3a8658404e1c0045aa 499 PRINTS PR00067 Catalase signature 293 320 2.2E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c12750 276379f54883fb3a8658404e1c0045aa 499 PRINTS PR00067 Catalase signature 26 49 2.2E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c12750 276379f54883fb3a8658404e1c0045aa 499 PRINTS PR00067 Catalase signature 128 146 2.2E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c12750 276379f54883fb3a8658404e1c0045aa 499 PRINTS PR00067 Catalase signature 88 106 2.2E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c12750 276379f54883fb3a8658404e1c0045aa 499 PRINTS PR00067 Catalase signature 109 126 2.2E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c12750 276379f54883fb3a8658404e1c0045aa 499 PRINTS PR00067 Catalase signature 325 351 2.2E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c12750 276379f54883fb3a8658404e1c0045aa 499 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 338 346 - T 12-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MIM_c32490 b4cc0c06d17302e2d3aa9d7b000abac7 474 Pfam PF01565 FAD binding domain 38 175 2.0E-37 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MIM_c32490 b4cc0c06d17302e2d3aa9d7b000abac7 474 Gene3D G3DSA:3.30.70.2190 215 341 2.6E-32 T 12-10-2018 MIM_c32490 b4cc0c06d17302e2d3aa9d7b000abac7 474 Gene3D G3DSA:1.10.45.10 429 469 3.2E-17 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 MIM_c32490 b4cc0c06d17302e2d3aa9d7b000abac7 474 Pfam PF02913 FAD linked oxidases, C-terminal domain 215 468 4.7E-53 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 MIM_c32490 b4cc0c06d17302e2d3aa9d7b000abac7 474 Gene3D G3DSA:3.30.43.10 1 91 3.0E-27 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 MIM_c32490 b4cc0c06d17302e2d3aa9d7b000abac7 474 SUPERFAMILY SSF55103 218 470 3.11E-57 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MIM_c32490 b4cc0c06d17302e2d3aa9d7b000abac7 474 Gene3D G3DSA:3.30.70.2740 342 428 9.5E-30 T 12-10-2018 MIM_c32490 b4cc0c06d17302e2d3aa9d7b000abac7 474 Gene3D G3DSA:3.30.465.10 93 214 6.0E-46 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MIM_c32490 b4cc0c06d17302e2d3aa9d7b000abac7 474 SUPERFAMILY SSF56176 2 215 1.06E-77 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MIM_c13880 1bc389871d5f6389aa03de86af059081 328 SUPERFAMILY SSF63829 33 303 3.6E-51 T 12-10-2018 MIM_c13880 1bc389871d5f6389aa03de86af059081 328 Gene3D G3DSA:2.120.10.30 10 328 8.6E-100 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MIM_c13880 1bc389871d5f6389aa03de86af059081 328 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 56 279 1.2E-25 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region MIM_c26800 fe1f3d135e2bc25b341490f1990d9e89 271 SUPERFAMILY SSF52540 1 269 8.0E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c26800 fe1f3d135e2bc25b341490f1990d9e89 271 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 268 4.7E-104 T 12-10-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 MIM_c26800 fe1f3d135e2bc25b341490f1990d9e89 271 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 226 1.4E-18 T 12-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain MIM_c26800 fe1f3d135e2bc25b341490f1990d9e89 271 PIRSF PIRSF003092 1 271 1.7E-92 T 12-10-2018 IPR025501 ATP binding protein MinD MIM_c26800 fe1f3d135e2bc25b341490f1990d9e89 271 Gene3D G3DSA:3.40.50.300 1 260 1.8E-70 T 12-10-2018 MIM_c05060 09c3259b962536aef6575d3d158a52ec 443 SUPERFAMILY SSF52540 5 438 6.21E-84 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c05060 09c3259b962536aef6575d3d158a52ec 443 SMART SM01086 335 431 1.3E-20 T 12-10-2018 IPR019489 Clp ATPase, C-terminal MIM_c05060 09c3259b962536aef6575d3d158a52ec 443 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 55 102 1.6E-6 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MIM_c05060 09c3259b962536aef6575d3d158a52ec 443 Gene3D G3DSA:1.10.8.60 335 440 2.0E-36 T 12-10-2018 MIM_c05060 09c3259b962536aef6575d3d158a52ec 443 Pfam PF07724 AAA domain (Cdc48 subfamily) 187 329 7.6E-40 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MIM_c05060 09c3259b962536aef6575d3d158a52ec 443 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 335 407 7.4E-6 T 12-10-2018 IPR019489 Clp ATPase, C-terminal MIM_c05060 09c3259b962536aef6575d3d158a52ec 443 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 3 443 42.623 T 12-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 MIM_c05060 09c3259b962536aef6575d3d158a52ec 443 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 6 443 1.1E-202 T 12-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 MIM_c05060 09c3259b962536aef6575d3d158a52ec 443 SMART SM00382 51 332 1.2E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c08020 2f05ca55210f1c6534d22b6e24c3ff78 554 Gene3D G3DSA:3.40.190.10 222 539 1.2E-88 T 12-10-2018 MIM_c08020 2f05ca55210f1c6534d22b6e24c3ff78 554 Gene3D G3DSA:3.10.105.10 304 529 1.2E-88 T 12-10-2018 MIM_c08020 2f05ca55210f1c6534d22b6e24c3ff78 554 SUPERFAMILY SSF53850 61 552 7.96E-93 T 12-10-2018 MIM_c08020 2f05ca55210f1c6534d22b6e24c3ff78 554 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 85 465 2.0E-62 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain MIM_c08020 2f05ca55210f1c6534d22b6e24c3ff78 554 PIRSF PIRSF002741 64 547 6.9E-57 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MIM_c08020 2f05ca55210f1c6534d22b6e24c3ff78 554 Gene3D G3DSA:3.90.76.10 63 221 1.2E-88 T 12-10-2018 MIM_c31970 55434f51b4663a3364374d01c174e37e 290 Gene3D G3DSA:3.40.50.300 18 195 1.2E-9 T 12-10-2018 MIM_c31970 55434f51b4663a3364374d01c174e37e 290 SUPERFAMILY SSF52540 41 273 1.92E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c31970 55434f51b4663a3364374d01c174e37e 290 Pfam PF05621 Bacterial TniB protein 17 264 1.1E-21 T 12-10-2018 IPR008868 Bacterial TniB MIM_c29150 966ab00937c76576efb8059f996fdcb6 105 Pfam PF13744 Helix-turn-helix domain 28 85 4.3E-11 T 12-10-2018 IPR039554 HigA2-like, helix-turn-helix domain MIM_c29150 966ab00937c76576efb8059f996fdcb6 105 Gene3D G3DSA:1.10.260.40 20 89 6.1E-14 T 12-10-2018 MIM_c29150 966ab00937c76576efb8059f996fdcb6 105 SUPERFAMILY SSF47413 23 85 8.04E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c29150 966ab00937c76576efb8059f996fdcb6 105 SMART SM00530 29 84 4.0E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c27880 4e033640ac29b94d7302f258b9a5765e 516 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 458 1.7E-161 T 12-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 MIM_c27880 4e033640ac29b94d7302f258b9a5765e 516 SUPERFAMILY SSF143968 350 514 9.02E-66 T 12-10-2018 MIM_c27880 4e033640ac29b94d7302f258b9a5765e 516 SUPERFAMILY SSF50475 3 349 7.45E-107 T 12-10-2018 MIM_c27880 4e033640ac29b94d7302f258b9a5765e 516 Gene3D G3DSA:1.20.5.570 482 516 2.3E-14 T 12-10-2018 MIM_c27880 4e033640ac29b94d7302f258b9a5765e 516 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 281 4.1E-77 T 12-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 MIM_c27880 4e033640ac29b94d7302f258b9a5765e 516 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 305 482 1.6E-76 T 12-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 MIM_c27880 4e033640ac29b94d7302f258b9a5765e 516 Hamap MF_01636 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [ubiD]. 1 514 70.625 T 12-10-2018 IPR023677 UbiD decarboxylyase, bacteria GO:0005886|GO:0006744|GO:0008694 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 MIM_c27880 4e033640ac29b94d7302f258b9a5765e 516 Gene3D G3DSA:3.40.1670.10 364 481 1.3E-50 T 12-10-2018 MIM_c30430 bf21029a45235f33188878e067e26b59 283 SUPERFAMILY SSF53850 35 265 2.92E-56 T 12-10-2018 MIM_c30430 bf21029a45235f33188878e067e26b59 283 Gene3D G3DSA:3.40.190.10 135 224 9.9E-60 T 12-10-2018 MIM_c30430 bf21029a45235f33188878e067e26b59 283 SMART SM00062 45 266 2.2E-48 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c30430 bf21029a45235f33188878e067e26b59 283 Gene3D G3DSA:3.40.190.10 40 257 9.9E-60 T 12-10-2018 MIM_c30430 bf21029a45235f33188878e067e26b59 283 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 46 263 7.3E-45 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c18510 ffb1db24a4d52dcc612fd1a8c57d6341 165 SUPERFAMILY SSF52788 2 155 1.57E-53 T 12-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily MIM_c18510 ffb1db24a4d52dcc612fd1a8c57d6341 165 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 150 2.0E-41 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I MIM_c18510 ffb1db24a4d52dcc612fd1a8c57d6341 165 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 84 99 3.4E-22 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MIM_c18510 ffb1db24a4d52dcc612fd1a8c57d6341 165 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 126 141 3.4E-22 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MIM_c18510 ffb1db24a4d52dcc612fd1a8c57d6341 165 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 50 66 3.4E-22 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MIM_c18510 ffb1db24a4d52dcc612fd1a8c57d6341 165 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 7 24 3.4E-22 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MIM_c18510 ffb1db24a4d52dcc612fd1a8c57d6341 165 Gene3D G3DSA:3.40.50.2300 1 161 3.8E-59 T 12-10-2018 MIM_c18510 ffb1db24a4d52dcc612fd1a8c57d6341 165 SMART SM00226 5 154 1.2E-46 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I MIM_c14420 056179465ee07f27abd1812cf8547565 315 Gene3D G3DSA:2.130.10.10 65 156 2.1E-26 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MIM_c14420 056179465ee07f27abd1812cf8547565 315 Gene3D G3DSA:2.130.10.10 18 64 4.3E-7 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MIM_c14420 056179465ee07f27abd1812cf8547565 315 SMART SM00320 212 251 0.82 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 MIM_c14420 056179465ee07f27abd1812cf8547565 315 SMART SM00320 127 167 72.0 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 MIM_c14420 056179465ee07f27abd1812cf8547565 315 SMART SM00320 254 293 43.0 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 MIM_c14420 056179465ee07f27abd1812cf8547565 315 SUPERFAMILY SSF50974 9 313 5.49E-79 T 12-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 MIM_c14420 056179465ee07f27abd1812cf8547565 315 Pfam PF10282 Lactonase, 7-bladed beta-propeller 175 295 2.0E-11 T 12-10-2018 IPR019405 Lactonase, 7-bladed beta propeller MIM_c14420 056179465ee07f27abd1812cf8547565 315 Pfam PF02239 Cytochrome D1 heme domain 34 138 2.6E-6 T 12-10-2018 MIM_c14420 056179465ee07f27abd1812cf8547565 315 Gene3D G3DSA:2.130.10.10 157 315 7.3E-52 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MIM_c14420 056179465ee07f27abd1812cf8547565 315 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 274 314 5.2E-16 T 12-10-2018 IPR011964 YVTN beta-propeller repeat MIM_c14420 056179465ee07f27abd1812cf8547565 315 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 232 273 6.4E-14 T 12-10-2018 IPR011964 YVTN beta-propeller repeat MIM_c12810 659ab44b3f62c3b87763d9b57e254ef7 294 Gene3D G3DSA:3.40.50.10490 106 288 2.9E-26 T 12-10-2018 MIM_c12810 659ab44b3f62c3b87763d9b57e254ef7 294 SUPERFAMILY SSF53697 112 268 4.0E-19 T 12-10-2018 MIM_c12810 659ab44b3f62c3b87763d9b57e254ef7 294 SUPERFAMILY SSF46689 17 86 7.08E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c12810 659ab44b3f62c3b87763d9b57e254ef7 294 Pfam PF01380 SIS domain 141 261 2.3E-10 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MIM_c12810 659ab44b3f62c3b87763d9b57e254ef7 294 Pfam PF01418 Helix-turn-helix domain, rpiR family 17 86 5.2E-11 T 12-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 MIM_c12810 659ab44b3f62c3b87763d9b57e254ef7 294 Gene3D G3DSA:1.10.10.10 9 91 5.1E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c02260 2c7447b965c6c339f2f76bcfc72fceae 165 SUPERFAMILY SSF54593 6 162 4.03E-43 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c02260 2c7447b965c6c339f2f76bcfc72fceae 165 Gene3D G3DSA:3.10.180.70 2 165 1.1E-61 T 12-10-2018 MIM_c02260 2c7447b965c6c339f2f76bcfc72fceae 165 PIRSF PIRSF021700 2 164 1.7E-55 T 12-10-2018 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase MIM_c02260 2c7447b965c6c339f2f76bcfc72fceae 165 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 6 126 6.2E-45 T 12-10-2018 IPR028973 PhnB-like MIM_c17700 f34b637a7867b83f22c7de0836983ad9 196 Gene3D G3DSA:3.10.450.50 4 196 9.7E-54 T 12-10-2018 MIM_c17700 f34b637a7867b83f22c7de0836983ad9 196 Pfam PF00866 Ring hydroxylating beta subunit 38 188 3.1E-33 T 12-10-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0006725|GO:0055114 MIM_c17700 f34b637a7867b83f22c7de0836983ad9 196 SUPERFAMILY SSF54427 25 196 9.57E-37 T 12-10-2018 IPR032710 NTF2-like domain superfamily MIM_c07310 7a93f7974c51a6fd4f061f10bf211701 244 Gene3D G3DSA:3.40.190.10 112 202 3.9E-69 T 12-10-2018 MIM_c07310 7a93f7974c51a6fd4f061f10bf211701 244 Gene3D G3DSA:3.40.190.10 29 239 3.9E-69 T 12-10-2018 MIM_c07310 7a93f7974c51a6fd4f061f10bf211701 244 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 27 241 2.7E-64 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c07310 7a93f7974c51a6fd4f061f10bf211701 244 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 48 61 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site MIM_c07310 7a93f7974c51a6fd4f061f10bf211701 244 SUPERFAMILY SSF53850 1 241 5.3E-72 T 12-10-2018 MIM_c07310 7a93f7974c51a6fd4f061f10bf211701 244 SMART SM00062 26 243 1.8E-69 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c07310 7a93f7974c51a6fd4f061f10bf211701 244 SMART SM00079 26 242 8.4E-6 T 12-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 MIM_c01110 a334ec46ea65543739c33e2a5861a899 516 Gene3D G3DSA:3.40.50.12780 7 406 6.9E-109 T 12-10-2018 MIM_c01110 a334ec46ea65543739c33e2a5861a899 516 SUPERFAMILY SSF56801 8 508 7.98E-139 T 12-10-2018 MIM_c01110 a334ec46ea65543739c33e2a5861a899 516 Gene3D G3DSA:3.30.300.30 408 514 8.5E-27 T 12-10-2018 MIM_c01110 a334ec46ea65543739c33e2a5861a899 516 ProSitePatterns PS00455 Putative AMP-binding domain signature. 167 178 - T 12-10-2018 IPR020845 AMP-binding, conserved site MIM_c01110 a334ec46ea65543739c33e2a5861a899 516 Pfam PF00501 AMP-binding enzyme 20 413 1.8E-94 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MIM_c01110 a334ec46ea65543739c33e2a5861a899 516 Pfam PF13193 AMP-binding enzyme C-terminal domain 422 497 2.6E-18 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MIM_c11680 f8cfa4b6293ed7a2a7748fa18ad516c8 1358 Pfam PF00550 Phosphopantetheine attachment site 543 597 2.3E-4 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain MIM_c11680 f8cfa4b6293ed7a2a7748fa18ad516c8 1358 SUPERFAMILY SSF51161 976 1089 5.13E-18 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily MIM_c11680 f8cfa4b6293ed7a2a7748fa18ad516c8 1358 TIGRFAM TIGR02353 NRPS_term_dom: non-ribosomal peptide synthetase terminal domain of unknown function 631 1326 8.8E-209 T 12-10-2018 IPR012728 Non-ribosomal peptide synthetase, C-terminal MIM_c11680 f8cfa4b6293ed7a2a7748fa18ad516c8 1358 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 48 441 1.1E-120 T 12-10-2018 IPR010071 Amino acid adenylation domain MIM_c11680 f8cfa4b6293ed7a2a7748fa18ad516c8 1358 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 1034 1062 0.0017 T 12-10-2018 IPR001451 Hexapeptide repeat MIM_c11680 f8cfa4b6293ed7a2a7748fa18ad516c8 1358 SUPERFAMILY SSF47336 525 598 4.58E-8 T 12-10-2018 IPR036736 ACP-like superfamily MIM_c11680 f8cfa4b6293ed7a2a7748fa18ad516c8 1358 Gene3D G3DSA:3.30.300.30 410 515 6.0E-29 T 12-10-2018 MIM_c11680 f8cfa4b6293ed7a2a7748fa18ad516c8 1358 SUPERFAMILY SSF51161 1173 1332 4.16E-17 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily MIM_c11680 f8cfa4b6293ed7a2a7748fa18ad516c8 1358 Gene3D G3DSA:1.10.1200.10 516 608 6.9E-12 T 12-10-2018 IPR036736 ACP-like superfamily MIM_c11680 f8cfa4b6293ed7a2a7748fa18ad516c8 1358 ProSitePatterns PS00012 Phosphopantetheine attachment site. 556 571 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site MIM_c11680 f8cfa4b6293ed7a2a7748fa18ad516c8 1358 SUPERFAMILY SSF56801 20 528 1.31E-138 T 12-10-2018 MIM_c11680 f8cfa4b6293ed7a2a7748fa18ad516c8 1358 SUPERFAMILY SSF51161 729 847 7.35E-13 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily MIM_c11680 f8cfa4b6293ed7a2a7748fa18ad516c8 1358 Pfam PF00501 AMP-binding enzyme 27 417 1.1E-87 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MIM_c11680 f8cfa4b6293ed7a2a7748fa18ad516c8 1358 Gene3D G3DSA:2.160.10.10 727 851 1.5E-6 T 12-10-2018 MIM_c11680 f8cfa4b6293ed7a2a7748fa18ad516c8 1358 Gene3D G3DSA:2.160.10.10 1227 1348 4.8E-14 T 12-10-2018 MIM_c11680 f8cfa4b6293ed7a2a7748fa18ad516c8 1358 Gene3D G3DSA:3.40.50.12780 18 409 1.0E-114 T 12-10-2018 MIM_c11680 f8cfa4b6293ed7a2a7748fa18ad516c8 1358 Pfam PF13193 AMP-binding enzyme C-terminal domain 425 502 7.8E-8 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MIM_c11680 f8cfa4b6293ed7a2a7748fa18ad516c8 1358 ProSitePatterns PS00455 Putative AMP-binding domain signature. 168 179 - T 12-10-2018 IPR020845 AMP-binding, conserved site MIM_c11680 f8cfa4b6293ed7a2a7748fa18ad516c8 1358 Gene3D G3DSA:2.160.10.10 973 1105 8.2E-9 T 12-10-2018 MIM_c25330 54df04ca7260ff094fe84ec55ba96f14 471 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 66 7.4E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c25330 54df04ca7260ff094fe84ec55ba96f14 471 SMART SM00345 7 66 3.1E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c25330 54df04ca7260ff094fe84ec55ba96f14 471 Pfam PF00155 Aminotransferase class I and II 149 459 1.8E-34 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MIM_c25330 54df04ca7260ff094fe84ec55ba96f14 471 Gene3D G3DSA:3.40.640.10 143 361 4.0E-102 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c25330 54df04ca7260ff094fe84ec55ba96f14 471 SUPERFAMILY SSF53383 98 466 1.06E-92 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c25330 54df04ca7260ff094fe84ec55ba96f14 471 Gene3D G3DSA:3.90.1150.10 98 465 4.0E-102 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c25330 54df04ca7260ff094fe84ec55ba96f14 471 SUPERFAMILY SSF46785 2 70 1.63E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c25330 54df04ca7260ff094fe84ec55ba96f14 471 Gene3D G3DSA:1.10.10.10 1 67 4.8E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c22690 ad6a3a760718e1d79399bae4111e2f1b 219 TIGRFAM TIGR00781 ccoO: cytochrome c oxidase, cbb3-type, subunit II 11 189 1.5E-78 T 12-10-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO MIM_c22690 ad6a3a760718e1d79399bae4111e2f1b 219 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 11 193 3.1E-76 T 12-10-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO MIM_c22690 ad6a3a760718e1d79399bae4111e2f1b 219 Gene3D G3DSA:1.10.760.10 48 208 9.9E-68 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c22690 ad6a3a760718e1d79399bae4111e2f1b 219 SUPERFAMILY SSF46626 22 202 5.85E-26 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c29200 8c5c572018bdb03f1e46c65017482cfa 372 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 142 352 6.4E-58 T 12-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 MIM_c29200 8c5c572018bdb03f1e46c65017482cfa 372 Pfam PF01872 RibD C-terminal domain 144 328 2.3E-47 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 MIM_c29200 8c5c572018bdb03f1e46c65017482cfa 372 SUPERFAMILY SSF53927 1 139 1.57E-42 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 MIM_c29200 8c5c572018bdb03f1e46c65017482cfa 372 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 44 85 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MIM_c29200 8c5c572018bdb03f1e46c65017482cfa 372 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 1 348 1.5E-107 T 12-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 MIM_c29200 8c5c572018bdb03f1e46c65017482cfa 372 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 2 96 2.1E-18 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain MIM_c29200 8c5c572018bdb03f1e46c65017482cfa 372 Gene3D G3DSA:3.40.140.10 1 138 5.4E-42 T 12-10-2018 MIM_c29200 8c5c572018bdb03f1e46c65017482cfa 372 SUPERFAMILY SSF53597 142 350 4.38E-59 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MIM_c29200 8c5c572018bdb03f1e46c65017482cfa 372 Gene3D G3DSA:3.40.430.10 139 354 6.3E-67 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MIM_c29200 8c5c572018bdb03f1e46c65017482cfa 372 PIRSF PIRSF006769 1 355 6.6E-117 T 12-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 MIM_c25520 25bd7325bc867523e1b01619afce0893 104 Pfam PF06627 Protein of unknown function (DUF1153) 7 63 4.8E-7 T 12-10-2018 IPR009534 Protein of unknown function DUF1153 MIM_c25520 25bd7325bc867523e1b01619afce0893 104 Gene3D G3DSA:1.10.10.10 4 75 1.7E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c25520 25bd7325bc867523e1b01619afce0893 104 SUPERFAMILY SSF48295 2 67 5.75E-15 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 MIM_c14920 ca3c1aad69f385d6cd8024a671e297e7 396 Gene3D G3DSA:3.90.1150.10 288 385 6.2E-130 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c14920 ca3c1aad69f385d6cd8024a671e297e7 396 Gene3D G3DSA:3.40.640.10 64 287 6.2E-130 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c14920 ca3c1aad69f385d6cd8024a671e297e7 396 SUPERFAMILY SSF53383 1 389 5.59E-106 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c14920 ca3c1aad69f385d6cd8024a671e297e7 396 Pfam PF00155 Aminotransferase class I and II 31 375 1.3E-56 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MIM_c17990 dbd600f2ffb932b13dd1678569edfd2b 440 Pfam PF00709 Adenylosuccinate synthetase 11 429 1.9E-177 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MIM_c17990 dbd600f2ffb932b13dd1678569edfd2b 440 SMART SM00788 10 430 2.5E-298 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MIM_c17990 dbd600f2ffb932b13dd1678569edfd2b 440 Gene3D G3DSA:3.40.440.10 12 255 3.7E-102 T 12-10-2018 MIM_c17990 dbd600f2ffb932b13dd1678569edfd2b 440 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 440 211.912 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MIM_c17990 dbd600f2ffb932b13dd1678569edfd2b 440 Gene3D G3DSA:1.10.300.10 108 207 3.7E-102 T 12-10-2018 MIM_c17990 dbd600f2ffb932b13dd1678569edfd2b 440 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 12 433 8.5E-178 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MIM_c17990 dbd600f2ffb932b13dd1678569edfd2b 440 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 139 150 - T 12-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MIM_c17990 dbd600f2ffb932b13dd1678569edfd2b 440 Gene3D G3DSA:3.90.170.10 273 437 7.1E-65 T 12-10-2018 MIM_c17990 dbd600f2ffb932b13dd1678569edfd2b 440 SUPERFAMILY SSF52540 9 435 2.97E-177 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c17990 dbd600f2ffb932b13dd1678569edfd2b 440 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 17 24 - T 12-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MIM_c15590 1f1d79751e52d93e67db448a4bf521a0 817 SUPERFAMILY SSF50249 670 750 1.79E-19 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c15590 1f1d79751e52d93e67db448a4bf521a0 817 SUPERFAMILY SSF50249 196 669 2.11E-131 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c15590 1f1d79751e52d93e67db448a4bf521a0 817 Pfam PF08206 Ribonuclease B OB domain 97 153 6.4E-21 T 12-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain MIM_c15590 1f1d79751e52d93e67db448a4bf521a0 817 SMART SM00955 269 609 3.6E-172 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 MIM_c15590 1f1d79751e52d93e67db448a4bf521a0 817 SUPERFAMILY SSF50249 81 156 2.35E-18 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c15590 1f1d79751e52d93e67db448a4bf521a0 817 Pfam PF00773 RNB domain 269 609 6.7E-101 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 MIM_c15590 1f1d79751e52d93e67db448a4bf521a0 817 TIGRFAM TIGR02063 RNase_R: ribonuclease R 29 752 2.3E-246 T 12-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 MIM_c15590 1f1d79751e52d93e67db448a4bf521a0 817 SMART SM00357 96 154 1.2E-12 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 MIM_c15590 1f1d79751e52d93e67db448a4bf521a0 817 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 92 751 1.3E-202 T 12-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 MIM_c15590 1f1d79751e52d93e67db448a4bf521a0 817 ProSitePatterns PS01175 Ribonuclease II family signature. 576 600 - T 12-10-2018 IPR022966 Ribonuclease II/R, conserved site MIM_c15590 1f1d79751e52d93e67db448a4bf521a0 817 Gene3D G3DSA:2.40.50.140 85 157 1.8E-19 T 12-10-2018 MIM_c15590 1f1d79751e52d93e67db448a4bf521a0 817 SMART SM00316 668 751 9.7E-14 T 12-10-2018 IPR022967 RNA-binding domain, S1 MIM_c15590 1f1d79751e52d93e67db448a4bf521a0 817 Gene3D G3DSA:2.40.50.140 671 778 1.2E-22 T 12-10-2018 MIM_c15590 1f1d79751e52d93e67db448a4bf521a0 817 Hamap MF_01895 Ribonuclease R [rnr]. 48 751 53.577 T 12-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 MIM_c15590 1f1d79751e52d93e67db448a4bf521a0 817 Pfam PF00575 S1 RNA binding domain 669 749 4.4E-13 T 12-10-2018 IPR003029 S1 domain GO:0003676 MIM_c01280 6a70607ec5d0fc990a2a1d427967cc34 423 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 35 50 - T 12-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site MIM_c01280 6a70607ec5d0fc990a2a1d427967cc34 423 SUPERFAMILY SSF118215 8 402 1.83E-112 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MIM_c01280 6a70607ec5d0fc990a2a1d427967cc34 423 Gene3D G3DSA:1.10.3860.10 1 416 3.0E-116 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MIM_c01280 6a70607ec5d0fc990a2a1d427967cc34 423 PRINTS PR00173 Glutamate-aspartate symporter signature 327 346 5.9E-31 T 12-10-2018 MIM_c01280 6a70607ec5d0fc990a2a1d427967cc34 423 PRINTS PR00173 Glutamate-aspartate symporter signature 43 63 5.9E-31 T 12-10-2018 MIM_c01280 6a70607ec5d0fc990a2a1d427967cc34 423 PRINTS PR00173 Glutamate-aspartate symporter signature 292 318 5.9E-31 T 12-10-2018 MIM_c01280 6a70607ec5d0fc990a2a1d427967cc34 423 PRINTS PR00173 Glutamate-aspartate symporter signature 2 22 5.9E-31 T 12-10-2018 MIM_c01280 6a70607ec5d0fc990a2a1d427967cc34 423 PRINTS PR00173 Glutamate-aspartate symporter signature 145 167 5.9E-31 T 12-10-2018 MIM_c01280 6a70607ec5d0fc990a2a1d427967cc34 423 PRINTS PR00173 Glutamate-aspartate symporter signature 192 211 5.9E-31 T 12-10-2018 MIM_c01280 6a70607ec5d0fc990a2a1d427967cc34 423 PRINTS PR00173 Glutamate-aspartate symporter signature 73 98 5.9E-31 T 12-10-2018 MIM_c01280 6a70607ec5d0fc990a2a1d427967cc34 423 Pfam PF00375 Sodium:dicarboxylate symporter family 8 400 1.9E-103 T 12-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MIM_c01280 6a70607ec5d0fc990a2a1d427967cc34 423 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 295 318 - T 12-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site MIM_c20360 3b5152c0caecf872894dc22cf857b3d7 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 3.4E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c20360 3b5152c0caecf872894dc22cf857b3d7 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 3.4E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c20360 3b5152c0caecf872894dc22cf857b3d7 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 3.4E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c20360 3b5152c0caecf872894dc22cf857b3d7 280 SUPERFAMILY SSF53474 2 269 3.86E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c20360 3b5152c0caecf872894dc22cf857b3d7 280 Pfam PF00561 alpha/beta hydrolase fold 27 126 2.2E-22 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c20360 3b5152c0caecf872894dc22cf857b3d7 280 Gene3D G3DSA:3.40.50.1820 5 271 5.2E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c11130 f2d1c43cb52a87758e8f27c243b48c5b 552 Pfam PF13193 AMP-binding enzyme C-terminal domain 455 529 2.4E-15 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MIM_c11130 f2d1c43cb52a87758e8f27c243b48c5b 552 Pfam PF00501 AMP-binding enzyme 24 445 2.9E-80 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MIM_c11130 f2d1c43cb52a87758e8f27c243b48c5b 552 ProSitePatterns PS00455 Putative AMP-binding domain signature. 188 199 - T 12-10-2018 IPR020845 AMP-binding, conserved site MIM_c11130 f2d1c43cb52a87758e8f27c243b48c5b 552 SUPERFAMILY SSF56801 17 538 1.96E-127 T 12-10-2018 MIM_c11130 f2d1c43cb52a87758e8f27c243b48c5b 552 Gene3D G3DSA:3.40.50.12780 4 440 1.7E-115 T 12-10-2018 MIM_c11130 f2d1c43cb52a87758e8f27c243b48c5b 552 Gene3D G3DSA:3.30.300.310 441 543 2.6E-29 T 12-10-2018 MIM_c06470 60661ac15a7285949f18e54780fc95d1 875 Gene3D G3DSA:3.40.50.300 367 555 1.5E-45 T 12-10-2018 MIM_c06470 60661ac15a7285949f18e54780fc95d1 875 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 226 359 5.7E-11 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MIM_c06470 60661ac15a7285949f18e54780fc95d1 875 SUPERFAMILY SSF52540 183 556 1.66E-72 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c06470 60661ac15a7285949f18e54780fc95d1 875 Pfam PF07724 AAA domain (Cdc48 subfamily) 607 773 5.6E-37 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MIM_c06470 60661ac15a7285949f18e54780fc95d1 875 SMART SM00382 608 751 4.3E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c06470 60661ac15a7285949f18e54780fc95d1 875 SMART SM00382 221 366 6.6E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c06470 60661ac15a7285949f18e54780fc95d1 875 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 780 855 5.7E-14 T 12-10-2018 IPR019489 Clp ATPase, C-terminal MIM_c06470 60661ac15a7285949f18e54780fc95d1 875 Gene3D G3DSA:1.10.1780.10 1 161 6.0E-41 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 MIM_c06470 60661ac15a7285949f18e54780fc95d1 875 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 657 675 3.4E-32 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 MIM_c06470 60661ac15a7285949f18e54780fc95d1 875 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 686 704 3.4E-32 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 MIM_c06470 60661ac15a7285949f18e54780fc95d1 875 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 612 630 3.4E-32 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 MIM_c06470 60661ac15a7285949f18e54780fc95d1 875 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 719 733 3.4E-32 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 MIM_c06470 60661ac15a7285949f18e54780fc95d1 875 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 317 329 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 MIM_c06470 60661ac15a7285949f18e54780fc95d1 875 Gene3D G3DSA:1.10.8.60 780 875 1.8E-13 T 12-10-2018 MIM_c06470 60661ac15a7285949f18e54780fc95d1 875 Gene3D G3DSA:3.40.50.300 178 365 1.5E-64 T 12-10-2018 MIM_c06470 60661ac15a7285949f18e54780fc95d1 875 SUPERFAMILY SSF81923 15 129 1.22E-15 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 MIM_c06470 60661ac15a7285949f18e54780fc95d1 875 Gene3D G3DSA:3.40.50.300 561 777 3.6E-63 T 12-10-2018 MIM_c06470 60661ac15a7285949f18e54780fc95d1 875 SUPERFAMILY SSF52540 557 871 2.63E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c06470 60661ac15a7285949f18e54780fc95d1 875 SMART SM01086 780 872 2.1E-17 T 12-10-2018 IPR019489 Clp ATPase, C-terminal MIM_c06470 60661ac15a7285949f18e54780fc95d1 875 TIGRFAM TIGR03345 VI_ClpV1: type VI secretion ATPase, ClpV1 family 14 864 0.0 T 12-10-2018 IPR017729 Type VI secretion system, ATPase ClpV1 MIM_c32900 dc76033df30440799d5b4a2bf4956b6b 969 Pfam PF02347 Glycine cleavage system P-protein 25 445 1.6E-180 T 12-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MIM_c32900 dc76033df30440799d5b4a2bf4956b6b 969 Pfam PF02347 Glycine cleavage system P-protein 467 742 2.1E-10 T 12-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MIM_c32900 dc76033df30440799d5b4a2bf4956b6b 969 Gene3D G3DSA:3.40.640.10 103 360 1.2E-108 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c32900 dc76033df30440799d5b4a2bf4956b6b 969 Gene3D G3DSA:3.40.640.10 529 760 4.8E-59 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c32900 dc76033df30440799d5b4a2bf4956b6b 969 Gene3D G3DSA:3.90.1150.10 775 915 3.2E-40 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c32900 dc76033df30440799d5b4a2bf4956b6b 969 SUPERFAMILY SSF53383 487 963 1.42E-99 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c32900 dc76033df30440799d5b4a2bf4956b6b 969 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 16 967 25.103 T 12-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MIM_c32900 dc76033df30440799d5b4a2bf4956b6b 969 SUPERFAMILY SSF53383 25 448 3.02E-103 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c32900 dc76033df30440799d5b4a2bf4956b6b 969 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 25 961 0.0 T 12-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MIM_c37030 50ee3e9a477baecbacdc54a4d1c437c6 109 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 5 102 2.8E-45 T 12-10-2018 IPR004480 Monothiol glutaredoxin-related MIM_c37030 50ee3e9a477baecbacdc54a4d1c437c6 109 PIRSF PIRSF005894 1 109 4.8E-48 T 12-10-2018 IPR014434 Monothiol glutaredoxin GO:0015036 Reactome: R-HSA-1362409 MIM_c37030 50ee3e9a477baecbacdc54a4d1c437c6 109 Gene3D G3DSA:3.40.30.10 8 104 5.2E-34 T 12-10-2018 MIM_c37030 50ee3e9a477baecbacdc54a4d1c437c6 109 SUPERFAMILY SSF52833 1 106 2.16E-33 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c37030 50ee3e9a477baecbacdc54a4d1c437c6 109 Pfam PF00462 Glutaredoxin 17 82 8.5E-19 T 12-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 MIM_c23290 96b54ebf38b5b944a55bfa60ff0bc1ab 204 ProSitePatterns PS01117 MarR-type HTH domain signature. 100 134 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MIM_c23290 96b54ebf38b5b944a55bfa60ff0bc1ab 204 Pfam PF01047 MarR family 68 126 2.7E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c23290 96b54ebf38b5b944a55bfa60ff0bc1ab 204 SMART SM00347 61 161 5.0E-23 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c23290 96b54ebf38b5b944a55bfa60ff0bc1ab 204 Gene3D G3DSA:1.10.10.10 34 174 1.6E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c23290 96b54ebf38b5b944a55bfa60ff0bc1ab 204 PRINTS PR00598 Bacterial regulatory protein MarR family signature 102 117 3.2E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c23290 96b54ebf38b5b944a55bfa60ff0bc1ab 204 PRINTS PR00598 Bacterial regulatory protein MarR family signature 121 137 3.2E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c23290 96b54ebf38b5b944a55bfa60ff0bc1ab 204 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 3.2E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c23290 96b54ebf38b5b944a55bfa60ff0bc1ab 204 PRINTS PR00598 Bacterial regulatory protein MarR family signature 151 171 3.2E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c23290 96b54ebf38b5b944a55bfa60ff0bc1ab 204 SUPERFAMILY SSF46785 43 176 2.12E-32 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c13480 f613d0efe766b8e93e327fbfce807453 791 SUPERFAMILY SSF158832 19 339 3.66E-109 T 12-10-2018 MIM_c13480 f613d0efe766b8e93e327fbfce807453 791 Gene3D G3DSA:1.10.3500.10 127 517 1.9E-149 T 12-10-2018 IPR023323 Tex-like domain superfamily MIM_c13480 f613d0efe766b8e93e327fbfce807453 791 Gene3D G3DSA:1.10.150.310 518 649 5.6E-49 T 12-10-2018 MIM_c13480 f613d0efe766b8e93e327fbfce807453 791 Gene3D G3DSA:3.30.420.140 343 470 1.9E-149 T 12-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 MIM_c13480 f613d0efe766b8e93e327fbfce807453 791 Pfam PF16921 Tex protein YqgF-like domain 344 470 2.0E-52 T 12-10-2018 IPR032639 Tex protein, YqgF-like domain MIM_c13480 f613d0efe766b8e93e327fbfce807453 791 Pfam PF09371 Tex-like protein N-terminal domain 24 208 1.1E-67 T 12-10-2018 IPR018974 Tex-like protein, N-terminal MIM_c13480 f613d0efe766b8e93e327fbfce807453 791 Gene3D G3DSA:2.40.50.140 650 744 2.1E-29 T 12-10-2018 MIM_c13480 f613d0efe766b8e93e327fbfce807453 791 SUPERFAMILY SSF47781 579 651 3.33E-19 T 12-10-2018 IPR010994 RuvA domain 2-like MIM_c13480 f613d0efe766b8e93e327fbfce807453 791 SMART SM00316 668 739 3.0E-25 T 12-10-2018 IPR022967 RNA-binding domain, S1 MIM_c13480 f613d0efe766b8e93e327fbfce807453 791 Gene3D G3DSA:1.10.10.650 17 124 1.9E-38 T 12-10-2018 IPR023319 Tex-like protein, HTH domain superfamily MIM_c13480 f613d0efe766b8e93e327fbfce807453 791 SUPERFAMILY SSF50249 657 741 1.12E-24 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c13480 f613d0efe766b8e93e327fbfce807453 791 SUPERFAMILY SSF47781 489 577 4.67E-26 T 12-10-2018 IPR010994 RuvA domain 2-like MIM_c13480 f613d0efe766b8e93e327fbfce807453 791 SUPERFAMILY SSF53098 340 488 8.34E-51 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily MIM_c13480 f613d0efe766b8e93e327fbfce807453 791 Pfam PF00575 S1 RNA binding domain 668 739 3.4E-22 T 12-10-2018 IPR003029 S1 domain GO:0003676 MIM_c13480 f613d0efe766b8e93e327fbfce807453 791 SMART SM00732 344 443 2.1E-37 T 12-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 MIM_c13480 f613d0efe766b8e93e327fbfce807453 791 Pfam PF12836 Helix-hairpin-helix motif 510 574 1.9E-25 T 12-10-2018 MIM_c11300 96cc47f66685ffd76cf8ce6bb11ea0d9 230 SUPERFAMILY SSF56784 5 217 6.78E-43 T 12-10-2018 IPR036412 HAD-like superfamily MIM_c11300 96cc47f66685ffd76cf8ce6bb11ea0d9 230 Pfam PF13419 Haloacid dehalogenase-like hydrolase 10 188 9.0E-31 T 12-10-2018 MIM_c11300 96cc47f66685ffd76cf8ce6bb11ea0d9 230 Gene3D G3DSA:1.10.150.240 22 88 1.5E-40 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MIM_c11300 96cc47f66685ffd76cf8ce6bb11ea0d9 230 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 81 183 7.2E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MIM_c11300 96cc47f66685ffd76cf8ce6bb11ea0d9 230 Gene3D G3DSA:3.40.50.1000 10 195 1.5E-40 T 12-10-2018 IPR023214 HAD superfamily MIM_c09510 fdd9e86c28457043ebda5a410a551d1e 473 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 11 469 2.5E-119 T 12-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 MIM_c09510 fdd9e86c28457043ebda5a410a551d1e 473 Gene3D G3DSA:1.20.1600.10 59 469 1.6E-130 T 12-10-2018 MIM_c09510 fdd9e86c28457043ebda5a410a551d1e 473 Gene3D G3DSA:2.20.200.10 105 358 1.6E-130 T 12-10-2018 MIM_c09510 fdd9e86c28457043ebda5a410a551d1e 473 SUPERFAMILY SSF56954 1 470 2.62E-107 T 12-10-2018 MIM_c09510 fdd9e86c28457043ebda5a410a551d1e 473 Pfam PF02321 Outer membrane efflux protein 70 258 7.9E-26 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MIM_c09510 fdd9e86c28457043ebda5a410a551d1e 473 Pfam PF02321 Outer membrane efflux protein 286 454 2.4E-27 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MIM_c39650 449680809085aa20cd4bb903d705098e 267 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 12-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39650 449680809085aa20cd4bb903d705098e 267 Pfam PF07650 KH domain 39 110 4.2E-19 T 12-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39650 449680809085aa20cd4bb903d705098e 267 SMART SM00322 60 125 3.2E-7 T 12-10-2018 IPR004087 K Homology domain GO:0003676 MIM_c39650 449680809085aa20cd4bb903d705098e 267 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 38.694 T 12-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 MIM_c39650 449680809085aa20cd4bb903d705098e 267 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 1.5E-92 T 12-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 MIM_c39650 449680809085aa20cd4bb903d705098e 267 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 5.7E-40 T 12-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39650 449680809085aa20cd4bb903d705098e 267 SUPERFAMILY SSF54821 108 206 1.83E-39 T 12-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39650 449680809085aa20cd4bb903d705098e 267 Gene3D G3DSA:3.30.300.20 17 107 2.3E-27 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta MIM_c39650 449680809085aa20cd4bb903d705098e 267 SUPERFAMILY SSF54814 2 106 7.33E-37 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 MIM_c39650 449680809085aa20cd4bb903d705098e 267 Gene3D G3DSA:3.30.1140.32 108 208 7.2E-44 T 12-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c13580 a8c515800f0e990eed40d6f71a9428b9 69 Pfam PF05532 CsbD-like 4 56 6.4E-19 T 12-10-2018 IPR008462 CsbD-like domain MIM_c13580 a8c515800f0e990eed40d6f71a9428b9 69 SUPERFAMILY SSF69047 1 67 3.53E-25 T 12-10-2018 IPR036629 YjbJ superfamily MIM_c13580 a8c515800f0e990eed40d6f71a9428b9 69 PIRSF PIRSF039008 1 66 5.7E-29 T 12-10-2018 IPR026042 Stress response protein YjbJ MIM_c13580 a8c515800f0e990eed40d6f71a9428b9 69 Gene3D G3DSA:1.10.1470.10 1 65 2.1E-30 T 12-10-2018 IPR036629 YjbJ superfamily MIM_c10030 de6e5291c370deebad1ec3a8eb6e0167 937 Pfam PF00694 Aconitase C-terminal domain 736 866 7.1E-43 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 MIM_c10030 de6e5291c370deebad1ec3a8eb6e0167 937 ProSitePatterns PS00450 Aconitase family signature 1. 472 488 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MIM_c10030 de6e5291c370deebad1ec3a8eb6e0167 937 SUPERFAMILY SSF53732 4 672 7.46E-220 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 MIM_c10030 de6e5291c370deebad1ec3a8eb6e0167 937 Gene3D G3DSA:3.20.19.10 698 937 1.8E-101 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 MIM_c10030 de6e5291c370deebad1ec3a8eb6e0167 937 PRINTS PR00415 Aconitase family signature 217 232 9.7E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c10030 de6e5291c370deebad1ec3a8eb6e0167 937 PRINTS PR00415 Aconitase family signature 476 487 9.7E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c10030 de6e5291c370deebad1ec3a8eb6e0167 937 PRINTS PR00415 Aconitase family signature 146 159 9.7E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c10030 de6e5291c370deebad1ec3a8eb6e0167 937 PRINTS PR00415 Aconitase family signature 170 178 9.7E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c10030 de6e5291c370deebad1ec3a8eb6e0167 937 PRINTS PR00415 Aconitase family signature 203 216 9.7E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c10030 de6e5291c370deebad1ec3a8eb6e0167 937 PRINTS PR00415 Aconitase family signature 538 551 9.7E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c10030 de6e5291c370deebad1ec3a8eb6e0167 937 PRINTS PR00415 Aconitase family signature 279 292 9.7E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c10030 de6e5291c370deebad1ec3a8eb6e0167 937 PRINTS PR00415 Aconitase family signature 293 306 9.7E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c10030 de6e5291c370deebad1ec3a8eb6e0167 937 PRINTS PR00415 Aconitase family signature 372 386 9.7E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c10030 de6e5291c370deebad1ec3a8eb6e0167 937 SUPERFAMILY SSF52016 677 936 6.08E-81 T 12-10-2018 MIM_c10030 de6e5291c370deebad1ec3a8eb6e0167 937 Gene3D G3DSA:1.10.1440.20 637 696 4.3E-19 T 12-10-2018 MIM_c10030 de6e5291c370deebad1ec3a8eb6e0167 937 Gene3D G3DSA:3.30.499.20 8 372 2.6E-157 T 12-10-2018 MIM_c10030 de6e5291c370deebad1ec3a8eb6e0167 937 Pfam PF00330 Aconitase family (aconitate hydratase) 69 607 3.1E-178 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c10030 de6e5291c370deebad1ec3a8eb6e0167 937 ProSitePatterns PS01244 Aconitase family signature 2. 538 551 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MIM_c07920 353fc200164d9a8f1bf26de55105afc1 307 Gene3D G3DSA:3.30.70.250 121 186 3.1E-47 T 12-10-2018 MIM_c07920 353fc200164d9a8f1bf26de55105afc1 307 Gene3D G3DSA:3.40.366.10 4 275 3.1E-47 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 MIM_c07920 353fc200164d9a8f1bf26de55105afc1 307 SUPERFAMILY SSF55048 124 181 5.23E-6 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding MIM_c07920 353fc200164d9a8f1bf26de55105afc1 307 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6 299 2.3E-8 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain MIM_c07920 353fc200164d9a8f1bf26de55105afc1 307 SUPERFAMILY SSF52151 2 290 6.02E-36 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase MIM_c30320 262ca59973a735b121d2fc84b57a5108 889 Pfam PF13298 DNA polymerase Ligase (LigD) 33 137 5.2E-35 T 12-10-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain MIM_c30320 262ca59973a735b121d2fc84b57a5108 889 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 606 849 3.9E-92 T 12-10-2018 IPR014145 DNA ligase D, polymerase domain MIM_c30320 262ca59973a735b121d2fc84b57a5108 889 Gene3D G3DSA:2.40.50.140 476 592 3.5E-27 T 12-10-2018 MIM_c30320 262ca59973a735b121d2fc84b57a5108 889 Gene3D G3DSA:3.30.470.30 316 429 1.6E-41 T 12-10-2018 MIM_c30320 262ca59973a735b121d2fc84b57a5108 889 Pfam PF04679 ATP dependent DNA ligase C terminal region 491 586 1.5E-17 T 12-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 MIM_c30320 262ca59973a735b121d2fc84b57a5108 889 TIGRFAM TIGR02777 LigD_PE_dom: DNA ligase D, 3'-phosphoesterase domain 3 156 1.8E-68 T 12-10-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain MIM_c30320 262ca59973a735b121d2fc84b57a5108 889 Gene3D G3DSA:3.30.1490.70 304 470 1.6E-41 T 12-10-2018 MIM_c30320 262ca59973a735b121d2fc84b57a5108 889 SUPERFAMILY SSF50249 478 591 3.34E-19 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c30320 262ca59973a735b121d2fc84b57a5108 889 Pfam PF01068 ATP dependent DNA ligase domain 305 472 2.6E-23 T 12-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 MIM_c30320 262ca59973a735b121d2fc84b57a5108 889 Gene3D G3DSA:3.90.920.30 613 889 1.5E-100 T 12-10-2018 MIM_c30320 262ca59973a735b121d2fc84b57a5108 889 TIGRFAM TIGR02776 NHEJ_ligase_prk: DNA ligase D 302 877 2.6E-179 T 12-10-2018 IPR014143 DNA ligase D MIM_c30320 262ca59973a735b121d2fc84b57a5108 889 SUPERFAMILY SSF56091 287 473 1.87E-43 T 12-10-2018 MIM_c30320 262ca59973a735b121d2fc84b57a5108 889 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 293 591 1.2E-86 T 12-10-2018 IPR014146 DNA ligase D, ligase domain MIM_c30420 cea5203f2e1b4c13d641afac85163d9e 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.6E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c30420 cea5203f2e1b4c13d641afac85163d9e 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.6E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c30420 cea5203f2e1b4c13d641afac85163d9e 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.6E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c30420 cea5203f2e1b4c13d641afac85163d9e 297 Pfam PF03466 LysR substrate binding domain 88 293 1.8E-32 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c30420 cea5203f2e1b4c13d641afac85163d9e 297 SUPERFAMILY SSF53850 90 295 2.65E-30 T 12-10-2018 MIM_c30420 cea5203f2e1b4c13d641afac85163d9e 297 Gene3D G3DSA:3.40.190.10 164 264 2.4E-30 T 12-10-2018 MIM_c30420 cea5203f2e1b4c13d641afac85163d9e 297 Gene3D G3DSA:1.10.10.10 1 92 6.6E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c30420 cea5203f2e1b4c13d641afac85163d9e 297 SUPERFAMILY SSF46785 1 110 1.72E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c30420 cea5203f2e1b4c13d641afac85163d9e 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 5.8E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c30420 cea5203f2e1b4c13d641afac85163d9e 297 Gene3D G3DSA:3.40.190.10 93 163 2.4E-30 T 12-10-2018 MIM_c04990 f8e6e2fbc911bd3333933bdb82ecc33b 461 Pfam PF00033 Cytochrome b/b6/petB 31 219 3.2E-69 T 12-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 MIM_c04990 f8e6e2fbc911bd3333933bdb82ecc33b 461 SUPERFAMILY SSF81342 15 287 3.45E-99 T 12-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 MIM_c04990 f8e6e2fbc911bd3333933bdb82ecc33b 461 PIRSF PIRSF038885 334 459 3.7E-20 T 12-10-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 MIM_c04990 f8e6e2fbc911bd3333933bdb82ecc33b 461 PIRSF PIRSF038885 4 340 2.0E-132 T 12-10-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 MIM_c04990 f8e6e2fbc911bd3333933bdb82ecc33b 461 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 285 433 1.6E-37 T 12-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 MIM_c04990 f8e6e2fbc911bd3333933bdb82ecc33b 461 Gene3D G3DSA:1.20.810.10 2 460 8.9E-150 T 12-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 MIM_c04990 f8e6e2fbc911bd3333933bdb82ecc33b 461 SUPERFAMILY SSF81648 289 340 1.5E-8 T 12-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 MIM_c04990 f8e6e2fbc911bd3333933bdb82ecc33b 461 SUPERFAMILY SSF81648 355 447 5.12E-16 T 12-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 MIM_c31790 4a71a54f333d1727e692468e05b61fcb 396 SUPERFAMILY SSF51604 117 371 1.21E-62 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MIM_c31790 4a71a54f333d1727e692468e05b61fcb 396 Gene3D G3DSA:3.30.390.10 10 370 3.1E-116 T 12-10-2018 IPR029017 Enolase-like, N-terminal MIM_c31790 4a71a54f333d1727e692468e05b61fcb 396 SMART SM00922 145 241 9.0E-13 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MIM_c31790 4a71a54f333d1727e692468e05b61fcb 396 SUPERFAMILY SSF54826 1 117 2.41E-22 T 12-10-2018 MIM_c31790 4a71a54f333d1727e692468e05b61fcb 396 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 34 117 4.9E-11 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain MIM_c31790 4a71a54f333d1727e692468e05b61fcb 396 Gene3D G3DSA:3.20.20.120 118 357 3.1E-116 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MIM_c31790 4a71a54f333d1727e692468e05b61fcb 396 Pfam PF13378 Enolase C-terminal domain-like 149 361 1.0E-47 T 12-10-2018 IPR029065 Enolase C-terminal domain-like MIM_c10430 cb3a5db9766e737913db0ebe8d71da4a 299 Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase 34 249 7.3E-48 T 12-10-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 MIM_c10430 cb3a5db9766e737913db0ebe8d71da4a 299 Gene3D G3DSA:1.10.800.10 9 296 1.9E-105 T 12-10-2018 IPR036951 Aromatic amino acid hydroxylase superfamily GO:0004497|GO:0005506|GO:0009072|GO:0055114 MIM_c10430 cb3a5db9766e737913db0ebe8d71da4a 299 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 227 246 4.3E-8 T 12-10-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 MIM_c10430 cb3a5db9766e737913db0ebe8d71da4a 299 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 195 213 4.3E-8 T 12-10-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 MIM_c10430 cb3a5db9766e737913db0ebe8d71da4a 299 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 90 112 4.3E-8 T 12-10-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 MIM_c10430 cb3a5db9766e737913db0ebe8d71da4a 299 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 154 173 4.3E-8 T 12-10-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 MIM_c10430 cb3a5db9766e737913db0ebe8d71da4a 299 TIGRFAM TIGR01267 Phe4hydrox_mono: phenylalanine-4-hydroxylase 25 272 5.7E-107 T 12-10-2018 IPR005960 Phenylalanine-4-hydroxylase, monomeric form GO:0004505|GO:0006559|GO:0055114 KEGG: 00360+1.14.16.1|KEGG: 00400+1.14.16.1|KEGG: 00790+1.14.16.1|MetaCyc: PWY-6134|MetaCyc: PWY-7158 MIM_c10430 cb3a5db9766e737913db0ebe8d71da4a 299 SUPERFAMILY SSF56534 21 281 3.14E-99 T 12-10-2018 IPR036329 Aromatic amino acid monoxygenase, C-terminal domain superfamily MIM_c31260 6fd0b845791c7cb3ee247c72e9c26cdb 191 SUPERFAMILY SSF88946 14 115 7.32E-18 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MIM_c31260 6fd0b845791c7cb3ee247c72e9c26cdb 191 Gene3D G3DSA:1.10.1740.10 11 102 6.3E-13 T 12-10-2018 MIM_c31260 6fd0b845791c7cb3ee247c72e9c26cdb 191 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 185 9.3E-20 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MIM_c31260 6fd0b845791c7cb3ee247c72e9c26cdb 191 Pfam PF08281 Sigma-70, region 4 132 183 4.9E-13 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MIM_c31260 6fd0b845791c7cb3ee247c72e9c26cdb 191 Pfam PF04542 Sigma-70 region 2 37 103 1.2E-10 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MIM_c31260 6fd0b845791c7cb3ee247c72e9c26cdb 191 Gene3D G3DSA:1.10.10.10 107 189 1.8E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c31260 6fd0b845791c7cb3ee247c72e9c26cdb 191 SUPERFAMILY SSF88659 125 186 3.92E-12 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MIM_c02310 bbd2491376c2fa1d6841db10ebb9606d 216 Gene3D G3DSA:3.90.550.10 14 208 1.2E-47 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MIM_c02310 bbd2491376c2fa1d6841db10ebb9606d 216 Pfam PF12804 MobA-like NTP transferase domain 18 180 3.0E-34 T 12-10-2018 IPR025877 MobA-like NTP transferase MIM_c02310 bbd2491376c2fa1d6841db10ebb9606d 216 SUPERFAMILY SSF53448 14 203 7.43E-29 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MIM_c28290 fe31eec71ae79777e597d9a2e9288666 242 SUPERFAMILY SSF46785 15 86 4.61E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c28290 fe31eec71ae79777e597d9a2e9288666 242 Gene3D G3DSA:1.20.120.530 101 242 6.6E-32 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c28290 fe31eec71ae79777e597d9a2e9288666 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 82 1.3E-22 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c28290 fe31eec71ae79777e597d9a2e9288666 242 SMART SM00345 23 82 1.8E-22 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c28290 fe31eec71ae79777e597d9a2e9288666 242 SUPERFAMILY SSF48008 103 240 2.62E-26 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c28290 fe31eec71ae79777e597d9a2e9288666 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 1.5E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c28290 fe31eec71ae79777e597d9a2e9288666 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 1.5E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c28290 fe31eec71ae79777e597d9a2e9288666 242 SMART SM00895 107 232 1.5E-23 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c28290 fe31eec71ae79777e597d9a2e9288666 242 Pfam PF07729 FCD domain 108 230 4.7E-24 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c28290 fe31eec71ae79777e597d9a2e9288666 242 Gene3D G3DSA:1.10.10.10 12 92 6.5E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c03420 e7c28935b56622ef121e318555107051 152 SUPERFAMILY SSF54637 14 150 8.87E-32 T 12-10-2018 IPR029069 HotDog domain superfamily MIM_c03420 e7c28935b56622ef121e318555107051 152 Pfam PF01575 MaoC like domain 14 118 8.1E-18 T 12-10-2018 IPR002539 MaoC-like dehydratase domain MIM_c03420 e7c28935b56622ef121e318555107051 152 Gene3D G3DSA:3.10.129.10 3 149 8.3E-38 T 12-10-2018 MIM_c38670 fefabad9e2aa73da0fab89c57b18d135 188 SUPERFAMILY SSF52540 19 181 6.68E-31 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c38670 fefabad9e2aa73da0fab89c57b18d135 188 Pfam PF01202 Shikimate kinase 25 177 4.5E-49 T 12-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MIM_c38670 fefabad9e2aa73da0fab89c57b18d135 188 ProSitePatterns PS01128 Shikimate kinase signature. 72 97 - T 12-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MIM_c38670 fefabad9e2aa73da0fab89c57b18d135 188 Hamap MF_00109 Shikimate kinase [aroK]. 16 182 29.495 T 12-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MIM_c38670 fefabad9e2aa73da0fab89c57b18d135 188 PRINTS PR01100 Shikimate kinase family signature 89 98 8.9E-26 T 12-10-2018 MIM_c38670 fefabad9e2aa73da0fab89c57b18d135 188 PRINTS PR01100 Shikimate kinase family signature 43 56 8.9E-26 T 12-10-2018 MIM_c38670 fefabad9e2aa73da0fab89c57b18d135 188 PRINTS PR01100 Shikimate kinase family signature 110 127 8.9E-26 T 12-10-2018 MIM_c38670 fefabad9e2aa73da0fab89c57b18d135 188 PRINTS PR01100 Shikimate kinase family signature 71 79 8.9E-26 T 12-10-2018 MIM_c38670 fefabad9e2aa73da0fab89c57b18d135 188 PRINTS PR01100 Shikimate kinase family signature 19 34 8.9E-26 T 12-10-2018 MIM_c38670 fefabad9e2aa73da0fab89c57b18d135 188 Gene3D G3DSA:3.40.50.300 12 186 1.0E-56 T 12-10-2018 MIM_c17820 a2c6342570a5fd058f1bf85325b3f755 285 PRINTS PR00069 Aldo-keto reductase signature 93 111 1.2E-47 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MIM_c17820 a2c6342570a5fd058f1bf85325b3f755 285 PRINTS PR00069 Aldo-keto reductase signature 195 219 1.2E-47 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MIM_c17820 a2c6342570a5fd058f1bf85325b3f755 285 PRINTS PR00069 Aldo-keto reductase signature 122 139 1.2E-47 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MIM_c17820 a2c6342570a5fd058f1bf85325b3f755 285 PRINTS PR00069 Aldo-keto reductase signature 156 185 1.2E-47 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MIM_c17820 a2c6342570a5fd058f1bf85325b3f755 285 PRINTS PR00069 Aldo-keto reductase signature 37 61 1.2E-47 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MIM_c17820 a2c6342570a5fd058f1bf85325b3f755 285 SUPERFAMILY SSF51430 5 268 5.24E-90 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MIM_c17820 a2c6342570a5fd058f1bf85325b3f755 285 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 122 139 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MIM_c17820 a2c6342570a5fd058f1bf85325b3f755 285 Gene3D G3DSA:3.20.20.100 1 282 3.7E-108 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MIM_c17820 a2c6342570a5fd058f1bf85325b3f755 285 PIRSF PIRSF000097 1 277 2.9E-82 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MIM_c17820 a2c6342570a5fd058f1bf85325b3f755 285 Pfam PF00248 Aldo/keto reductase family 17 259 2.1E-51 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain MIM_c07890 b4515b02cef62fa6decc7699d1de93c7 263 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 213 255 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MIM_c07890 b4515b02cef62fa6decc7699d1de93c7 263 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 228 243 6.3E-7 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MIM_c07890 b4515b02cef62fa6decc7699d1de93c7 263 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 243 259 6.3E-7 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MIM_c07890 b4515b02cef62fa6decc7699d1de93c7 263 Pfam PF00072 Response regulator receiver domain 25 136 3.0E-9 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c07890 b4515b02cef62fa6decc7699d1de93c7 263 SMART SM00342 176 259 1.2E-30 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c07890 b4515b02cef62fa6decc7699d1de93c7 263 Gene3D G3DSA:1.10.10.60 210 263 9.5E-18 T 12-10-2018 MIM_c07890 b4515b02cef62fa6decc7699d1de93c7 263 Gene3D G3DSA:3.40.50.2300 18 156 3.9E-15 T 12-10-2018 MIM_c07890 b4515b02cef62fa6decc7699d1de93c7 263 SUPERFAMILY SSF46689 161 209 4.66E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c07890 b4515b02cef62fa6decc7699d1de93c7 263 Gene3D G3DSA:1.10.10.60 157 209 4.7E-11 T 12-10-2018 MIM_c07890 b4515b02cef62fa6decc7699d1de93c7 263 SUPERFAMILY SSF46689 212 261 1.43E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c07890 b4515b02cef62fa6decc7699d1de93c7 263 SUPERFAMILY SSF52172 16 150 1.35E-18 T 12-10-2018 IPR011006 CheY-like superfamily MIM_c07890 b4515b02cef62fa6decc7699d1de93c7 263 Pfam PF12833 Helix-turn-helix domain 182 260 4.3E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c07890 b4515b02cef62fa6decc7699d1de93c7 263 SMART SM00448 22 136 3.0E-7 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c04290 31fef50ea88e4460a61662bb52d48a93 237 Gene3D G3DSA:1.10.10.10 14 93 3.9E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c04290 31fef50ea88e4460a61662bb52d48a93 237 SMART SM00895 101 224 9.9E-18 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c04290 31fef50ea88e4460a61662bb52d48a93 237 SUPERFAMILY SSF46785 28 119 3.3E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c04290 31fef50ea88e4460a61662bb52d48a93 237 SUPERFAMILY SSF48008 97 232 6.28E-22 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c04290 31fef50ea88e4460a61662bb52d48a93 237 Gene3D G3DSA:1.20.120.530 94 232 4.4E-26 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c04290 31fef50ea88e4460a61662bb52d48a93 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 30 91 1.5E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c04290 31fef50ea88e4460a61662bb52d48a93 237 Pfam PF07729 FCD domain 101 222 6.2E-20 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c04290 31fef50ea88e4460a61662bb52d48a93 237 SMART SM00345 33 91 1.1E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c35900 0528b0c13d4d67159bc4acc0f3c3bc7b 475 SUPERFAMILY SSF53732 3 470 6.54E-147 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 MIM_c35900 0528b0c13d4d67159bc4acc0f3c3bc7b 475 ProSitePatterns PS00450 Aconitase family signature 1. 342 358 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MIM_c35900 0528b0c13d4d67159bc4acc0f3c3bc7b 475 ProSitePatterns PS01244 Aconitase family signature 2. 402 415 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MIM_c35900 0528b0c13d4d67159bc4acc0f3c3bc7b 475 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 3 468 6.3E-179 T 12-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 MIM_c35900 0528b0c13d4d67159bc4acc0f3c3bc7b 475 Gene3D G3DSA:3.30.499.20 5 288 1.1E-84 T 12-10-2018 MIM_c35900 0528b0c13d4d67159bc4acc0f3c3bc7b 475 PRINTS PR00415 Aconitase family signature 197 210 2.0E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c35900 0528b0c13d4d67159bc4acc0f3c3bc7b 475 PRINTS PR00415 Aconitase family signature 121 134 2.0E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c35900 0528b0c13d4d67159bc4acc0f3c3bc7b 475 PRINTS PR00415 Aconitase family signature 84 97 2.0E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c35900 0528b0c13d4d67159bc4acc0f3c3bc7b 475 PRINTS PR00415 Aconitase family signature 211 224 2.0E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c35900 0528b0c13d4d67159bc4acc0f3c3bc7b 475 PRINTS PR00415 Aconitase family signature 288 302 2.0E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c35900 0528b0c13d4d67159bc4acc0f3c3bc7b 475 PRINTS PR00415 Aconitase family signature 402 415 2.0E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c35900 0528b0c13d4d67159bc4acc0f3c3bc7b 475 PRINTS PR00415 Aconitase family signature 135 150 2.0E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c35900 0528b0c13d4d67159bc4acc0f3c3bc7b 475 PRINTS PR00415 Aconitase family signature 110 118 2.0E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c35900 0528b0c13d4d67159bc4acc0f3c3bc7b 475 PRINTS PR00415 Aconitase family signature 346 357 2.0E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c35900 0528b0c13d4d67159bc4acc0f3c3bc7b 475 Gene3D G3DSA:3.30.499.10 327 475 2.1E-50 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 MIM_c35900 0528b0c13d4d67159bc4acc0f3c3bc7b 475 Pfam PF00330 Aconitase family (aconitate hydratase) 9 460 2.7E-134 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c40530 0dbe89437bda3cabd119c76b9c2fc0ca 294 Gene3D G3DSA:3.40.50.1820 1 293 5.5E-77 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c40530 0dbe89437bda3cabd119c76b9c2fc0ca 294 SUPERFAMILY SSF53474 5 293 5.01E-66 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c40530 0dbe89437bda3cabd119c76b9c2fc0ca 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 115 128 7.3E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c40530 0dbe89437bda3cabd119c76b9c2fc0ca 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 7.3E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c40530 0dbe89437bda3cabd119c76b9c2fc0ca 294 Pfam PF00561 alpha/beta hydrolase fold 29 133 3.5E-21 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c40530 0dbe89437bda3cabd119c76b9c2fc0ca 294 PRINTS PR00412 Epoxide hydrolase signature 33 51 2.5E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MIM_c40530 0dbe89437bda3cabd119c76b9c2fc0ca 294 PRINTS PR00412 Epoxide hydrolase signature 115 128 2.5E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MIM_c40530 0dbe89437bda3cabd119c76b9c2fc0ca 294 PRINTS PR00412 Epoxide hydrolase signature 269 291 2.5E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MIM_c40530 0dbe89437bda3cabd119c76b9c2fc0ca 294 PRINTS PR00412 Epoxide hydrolase signature 101 114 2.5E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MIM_c02010 4014b13ebec41c41c98e6596cc81a34c 271 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 242 264 7.3E-11 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal MIM_c02010 4014b13ebec41c41c98e6596cc81a34c 271 Gene3D G3DSA:3.40.50.300 13 265 3.7E-61 T 12-10-2018 MIM_c02010 4014b13ebec41c41c98e6596cc81a34c 271 Pfam PF00005 ABC transporter 32 192 2.8E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c02010 4014b13ebec41c41c98e6596cc81a34c 271 SUPERFAMILY SSF52540 16 264 1.6E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c02010 4014b13ebec41c41c98e6596cc81a34c 271 SMART SM00382 41 250 2.4E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c09770 1b4cfa2580a3e4500921695c7d80c6c3 470 SUPERFAMILY SSF53623 91 313 2.75E-68 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MIM_c09770 1b4cfa2580a3e4500921695c7d80c6c3 470 Gene3D G3DSA:3.90.190.20 313 469 1.0E-43 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MIM_c09770 1b4cfa2580a3e4500921695c7d80c6c3 470 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 7 462 2.0E-168 T 12-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MIM_c09770 1b4cfa2580a3e4500921695c7d80c6c3 470 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 5 470 42.702 T 12-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MIM_c09770 1b4cfa2580a3e4500921695c7d80c6c3 470 Gene3D G3DSA:3.40.50.720 6 92 3.5E-32 T 12-10-2018 MIM_c09770 1b4cfa2580a3e4500921695c7d80c6c3 470 SUPERFAMILY SSF51984 6 92 1.44E-29 T 12-10-2018 MIM_c09770 1b4cfa2580a3e4500921695c7d80c6c3 470 Pfam PF01225 Mur ligase family, catalytic domain 7 105 9.7E-28 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MIM_c09770 1b4cfa2580a3e4500921695c7d80c6c3 470 Gene3D G3DSA:3.40.1190.10 94 312 2.0E-74 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MIM_c09770 1b4cfa2580a3e4500921695c7d80c6c3 470 Pfam PF08245 Mur ligase middle domain 110 295 6.3E-28 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MIM_c09770 1b4cfa2580a3e4500921695c7d80c6c3 470 Pfam PF02875 Mur ligase family, glutamate ligase domain 316 409 8.6E-20 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 MIM_c09770 1b4cfa2580a3e4500921695c7d80c6c3 470 SUPERFAMILY SSF53244 314 461 3.82E-45 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MIM_c12050 b5c44facbeccd093235e8d1ed40ec953 694 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 296 471 8.6E-61 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MIM_c12050 b5c44facbeccd093235e8d1ed40ec953 694 Gene3D G3DSA:1.10.1040.50 478 694 7.3E-75 T 12-10-2018 MIM_c12050 b5c44facbeccd093235e8d1ed40ec953 694 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 93 113 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 MIM_c12050 b5c44facbeccd093235e8d1ed40ec953 694 SUPERFAMILY SSF48179 598 690 1.62E-19 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c12050 b5c44facbeccd093235e8d1ed40ec953 694 SUPERFAMILY SSF48179 475 617 1.19E-23 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c12050 b5c44facbeccd093235e8d1ed40ec953 694 Gene3D G3DSA:3.40.50.720 293 476 6.9E-65 T 12-10-2018 MIM_c12050 b5c44facbeccd093235e8d1ed40ec953 694 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 178 6.5E-38 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c12050 b5c44facbeccd093235e8d1ed40ec953 694 SUPERFAMILY SSF52096 2 287 1.55E-61 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c12050 b5c44facbeccd093235e8d1ed40ec953 694 Gene3D G3DSA:3.90.226.10 2 290 9.3E-80 T 12-10-2018 MIM_c12050 b5c44facbeccd093235e8d1ed40ec953 694 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 476 568 3.3E-22 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MIM_c12050 b5c44facbeccd093235e8d1ed40ec953 694 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 604 691 3.9E-5 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MIM_c12050 b5c44facbeccd093235e8d1ed40ec953 694 SUPERFAMILY SSF51735 292 471 3.12E-55 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c38790 92637faf4b1c03feabece0784dea1da7 337 Pfam PF00490 Delta-aminolevulinic acid dehydratase 12 331 4.1E-136 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MIM_c38790 92637faf4b1c03feabece0784dea1da7 337 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 252 264 - T 12-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MIM_c38790 92637faf4b1c03feabece0784dea1da7 337 PIRSF PIRSF001415 2 336 2.7E-144 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MIM_c38790 92637faf4b1c03feabece0784dea1da7 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 307 326 9.2E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MIM_c38790 92637faf4b1c03feabece0784dea1da7 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 252 268 9.2E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MIM_c38790 92637faf4b1c03feabece0784dea1da7 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 277 292 9.2E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MIM_c38790 92637faf4b1c03feabece0784dea1da7 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 160 179 9.2E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MIM_c38790 92637faf4b1c03feabece0784dea1da7 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 198 217 9.2E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MIM_c38790 92637faf4b1c03feabece0784dea1da7 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 129 143 9.2E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MIM_c38790 92637faf4b1c03feabece0784dea1da7 337 SUPERFAMILY SSF51569 6 334 1.76E-141 T 12-10-2018 MIM_c38790 92637faf4b1c03feabece0784dea1da7 337 Gene3D G3DSA:3.20.20.70 2 336 3.4E-143 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c38790 92637faf4b1c03feabece0784dea1da7 337 SMART SM01004 9 333 1.6E-230 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MIM_c06290 880859d4009289408d479260d9c8b7ad 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.5E-11 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c06290 880859d4009289408d479260d9c8b7ad 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.5E-11 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c06290 880859d4009289408d479260d9c8b7ad 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.5E-11 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c06290 880859d4009289408d479260d9c8b7ad 311 Gene3D G3DSA:3.40.190.10 91 269 3.4E-36 T 12-10-2018 MIM_c06290 880859d4009289408d479260d9c8b7ad 311 Gene3D G3DSA:3.40.190.10 164 266 3.4E-36 T 12-10-2018 MIM_c06290 880859d4009289408d479260d9c8b7ad 311 SUPERFAMILY SSF46785 1 108 5.14E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c06290 880859d4009289408d479260d9c8b7ad 311 Gene3D G3DSA:1.10.10.10 1 88 1.9E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c06290 880859d4009289408d479260d9c8b7ad 311 Pfam PF03466 LysR substrate binding domain 89 271 5.6E-33 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c06290 880859d4009289408d479260d9c8b7ad 311 SUPERFAMILY SSF53850 91 296 2.04E-32 T 12-10-2018 MIM_c06290 880859d4009289408d479260d9c8b7ad 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.4E-22 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c23900 a75df0e2851f24b68f9b146297c1fe90 78 Gene3D G3DSA:1.10.1200.10 1 78 1.5E-30 T 12-10-2018 IPR036736 ACP-like superfamily MIM_c23900 a75df0e2851f24b68f9b146297c1fe90 78 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 77 1.4E-35 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 MIM_c23900 a75df0e2851f24b68f9b146297c1fe90 78 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 76 5.0E-4 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 MIM_c23900 a75df0e2851f24b68f9b146297c1fe90 78 SUPERFAMILY SSF47336 2 76 6.41E-24 T 12-10-2018 IPR036736 ACP-like superfamily MIM_c23900 a75df0e2851f24b68f9b146297c1fe90 78 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.766 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 MIM_c23900 a75df0e2851f24b68f9b146297c1fe90 78 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site MIM_c23900 a75df0e2851f24b68f9b146297c1fe90 78 Pfam PF00550 Phosphopantetheine attachment site 6 73 1.0E-17 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain MIM_c28910 845bf8ae27e36e6acd66a336b2850684 383 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 139 149 - T 12-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 MIM_c28910 845bf8ae27e36e6acd66a336b2850684 383 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 61 69 - T 12-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 MIM_c28910 845bf8ae27e36e6acd66a336b2850684 383 Gene3D G3DSA:3.40.50.1170 53 262 1.0E-77 T 12-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 MIM_c28910 845bf8ae27e36e6acd66a336b2850684 383 Pfam PF00710 Asparaginase, N-terminal 58 246 5.1E-58 T 12-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 MIM_c28910 845bf8ae27e36e6acd66a336b2850684 383 PIRSF PIRSF500176 55 382 3.0E-80 T 12-10-2018 MIM_c28910 845bf8ae27e36e6acd66a336b2850684 383 TIGRFAM TIGR00520 asnASE_II: L-asparaginase, type II 42 380 2.3E-115 T 12-10-2018 IPR004550 L-asparaginase, type II GO:0004067|GO:0006528 MIM_c28910 845bf8ae27e36e6acd66a336b2850684 383 SUPERFAMILY SSF53774 57 373 1.57E-97 T 12-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 MIM_c28910 845bf8ae27e36e6acd66a336b2850684 383 SMART SM00870 58 375 4.6E-131 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c28910 845bf8ae27e36e6acd66a336b2850684 383 PRINTS PR00139 Asparaginase/glutaminase family signature 138 156 2.2E-22 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c28910 845bf8ae27e36e6acd66a336b2850684 383 PRINTS PR00139 Asparaginase/glutaminase family signature 59 70 2.2E-22 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c28910 845bf8ae27e36e6acd66a336b2850684 383 PRINTS PR00139 Asparaginase/glutaminase family signature 315 333 2.2E-22 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c28910 845bf8ae27e36e6acd66a336b2850684 383 Gene3D G3DSA:3.40.50.40 268 381 4.5E-36 T 12-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 MIM_c28910 845bf8ae27e36e6acd66a336b2850684 383 PIRSF PIRSF001220 53 382 2.2E-90 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c26360 5a091a6016b5d83cd087a717981f30e5 470 Gene3D G3DSA:1.10.3090.10 179 424 1.4E-80 T 12-10-2018 MIM_c26360 5a091a6016b5d83cd087a717981f30e5 470 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 25 446 2.0E-149 T 12-10-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 MIM_c26360 5a091a6016b5d83cd087a717981f30e5 470 Pfam PF12626 Polymerase A arginine-rich C-terminus 323 443 3.0E-36 T 12-10-2018 IPR025866 Polymerase A arginine-rich C-terminal domain MIM_c26360 5a091a6016b5d83cd087a717981f30e5 470 SUPERFAMILY SSF81891 179 387 2.35E-47 T 12-10-2018 MIM_c26360 5a091a6016b5d83cd087a717981f30e5 470 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 14 445 35.587 T 12-10-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 MIM_c26360 5a091a6016b5d83cd087a717981f30e5 470 Pfam PF01743 Poly A polymerase head domain 56 181 2.4E-34 T 12-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 MIM_c26360 5a091a6016b5d83cd087a717981f30e5 470 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 210 269 3.4E-17 T 12-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 MIM_c26360 5a091a6016b5d83cd087a717981f30e5 470 SUPERFAMILY SSF81301 28 177 3.27E-39 T 12-10-2018 MIM_c26360 5a091a6016b5d83cd087a717981f30e5 470 Gene3D G3DSA:3.30.460.10 22 177 3.7E-57 T 12-10-2018 MIM_c34910 9c047c0c969c62d62c17e473502ecb7f 279 Gene3D G3DSA:1.10.3720.10 66 268 6.6E-22 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c34910 9c047c0c969c62d62c17e473502ecb7f 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 275 2.8E-28 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c34910 9c047c0c969c62d62c17e473502ecb7f 279 SUPERFAMILY SSF161098 69 257 2.09E-27 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c32210 8c7bfce7b2beeb026991ee9ee6815307 531 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 371 381 - T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MIM_c32210 8c7bfce7b2beeb026991ee9ee6815307 531 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 21 38 - T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MIM_c32210 8c7bfce7b2beeb026991ee9ee6815307 531 Pfam PF01266 FAD dependent oxidoreductase 17 342 1.4E-52 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MIM_c32210 8c7bfce7b2beeb026991ee9ee6815307 531 SUPERFAMILY SSF54373 244 337 2.35E-7 T 12-10-2018 MIM_c32210 8c7bfce7b2beeb026991ee9ee6815307 531 Gene3D G3DSA:1.10.8.870 411 480 4.4E-25 T 12-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MIM_c32210 8c7bfce7b2beeb026991ee9ee6815307 531 Gene3D G3DSA:3.30.9.10 94 338 3.6E-136 T 12-10-2018 MIM_c32210 8c7bfce7b2beeb026991ee9ee6815307 531 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 399 495 4.8E-11 T 12-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MIM_c32210 8c7bfce7b2beeb026991ee9ee6815307 531 Gene3D G3DSA:3.50.50.60 17 385 3.6E-136 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c32210 8c7bfce7b2beeb026991ee9ee6815307 531 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 16 28 7.4E-30 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MIM_c32210 8c7bfce7b2beeb026991ee9ee6815307 531 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 29 39 7.4E-30 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MIM_c32210 8c7bfce7b2beeb026991ee9ee6815307 531 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 331 337 7.4E-30 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MIM_c32210 8c7bfce7b2beeb026991ee9ee6815307 531 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 90 102 7.4E-30 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MIM_c32210 8c7bfce7b2beeb026991ee9ee6815307 531 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 366 378 7.4E-30 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MIM_c32210 8c7bfce7b2beeb026991ee9ee6815307 531 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 45 57 7.4E-30 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MIM_c32210 8c7bfce7b2beeb026991ee9ee6815307 531 SUPERFAMILY SSF51905 14 393 8.1E-34 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c39790 84a34b4c3fc67c9c4f11874552f3bfc7 520 Pfam PF00005 ABC transporter 296 450 1.9E-15 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c39790 84a34b4c3fc67c9c4f11874552f3bfc7 520 Pfam PF00005 ABC transporter 39 195 6.6E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c39790 84a34b4c3fc67c9c4f11874552f3bfc7 520 Gene3D G3DSA:3.40.50.300 21 283 5.7E-54 T 12-10-2018 MIM_c39790 84a34b4c3fc67c9c4f11874552f3bfc7 520 ProSitePatterns PS00211 ABC transporters family signature. 423 437 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c39790 84a34b4c3fc67c9c4f11874552f3bfc7 520 SUPERFAMILY SSF52540 23 257 2.27E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c39790 84a34b4c3fc67c9c4f11874552f3bfc7 520 Gene3D G3DSA:3.40.50.300 288 518 5.8E-40 T 12-10-2018 MIM_c39790 84a34b4c3fc67c9c4f11874552f3bfc7 520 SMART SM00382 304 499 16.0 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c39790 84a34b4c3fc67c9c4f11874552f3bfc7 520 SMART SM00382 48 250 2.8E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c39790 84a34b4c3fc67c9c4f11874552f3bfc7 520 SUPERFAMILY SSF52540 294 512 2.17E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c15530 3c17f458fa4fb5e46285d238029e2323 338 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 25 334 7.7E-131 T 12-10-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 MIM_c15530 3c17f458fa4fb5e46285d238029e2323 338 SUPERFAMILY SSF53850 28 335 4.31E-77 T 12-10-2018 MIM_c15530 3c17f458fa4fb5e46285d238029e2323 338 Gene3D G3DSA:3.40.190.10 35 304 5.6E-128 T 12-10-2018 MIM_c15530 3c17f458fa4fb5e46285d238029e2323 338 Gene3D G3DSA:3.40.190.10 123 333 5.6E-128 T 12-10-2018 MIM_c15530 3c17f458fa4fb5e46285d238029e2323 338 ProSitePatterns PS00401 Prokaryotic sulfate-binding proteins signature 1. 56 68 - T 12-10-2018 IPR000957 Sulphate/thiosulphate-binding, conserved site MIM_c15530 3c17f458fa4fb5e46285d238029e2323 338 Pfam PF13531 Bacterial extracellular solute-binding protein 41 289 1.8E-39 T 12-10-2018 MIM_c15530 3c17f458fa4fb5e46285d238029e2323 338 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 154 162 - T 12-10-2018 IPR034408 Sulphate/thiosulphate-binding site GO:1901681 MIM_c39910 2ddffb4668a0976c289f591f3f56c5e4 300 SUPERFAMILY SSF54001 8 277 1.47E-44 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily MIM_c39910 2ddffb4668a0976c289f591f3f56c5e4 300 SMART SM00460 181 251 6.8E-20 T 12-10-2018 IPR002931 Transglutaminase-like MIM_c39910 2ddffb4668a0976c289f591f3f56c5e4 300 Pfam PF01841 Transglutaminase-like superfamily 138 249 1.2E-21 T 12-10-2018 IPR002931 Transglutaminase-like MIM_c39910 2ddffb4668a0976c289f591f3f56c5e4 300 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 4 82 3.8E-22 T 12-10-2018 IPR013589 Bacterial transglutaminase-like, N-terminal MIM_c39910 2ddffb4668a0976c289f591f3f56c5e4 300 Gene3D G3DSA:3.10.620.30 100 288 1.4E-45 T 12-10-2018 MIM_c19510 6d742f64412359d88c3dbd97356b088e 788 SUPERFAMILY SSF56059 1 384 6.47E-108 T 12-10-2018 MIM_c19510 6d742f64412359d88c3dbd97356b088e 788 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 480 786 1.1E-54 T 12-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 MIM_c19510 6d742f64412359d88c3dbd97356b088e 788 Gene3D G3DSA:3.20.20.60 477 788 2.6E-95 T 12-10-2018 MIM_c19510 6d742f64412359d88c3dbd97356b088e 788 SUPERFAMILY SSF51621 466 787 3.14E-89 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MIM_c19510 6d742f64412359d88c3dbd97356b088e 788 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 413 424 - T 12-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 MIM_c19510 6d742f64412359d88c3dbd97356b088e 788 Gene3D G3DSA:3.50.30.10 356 466 3.5E-40 T 12-10-2018 MIM_c19510 6d742f64412359d88c3dbd97356b088e 788 Gene3D G3DSA:3.30.470.20 191 355 2.0E-55 T 12-10-2018 MIM_c19510 6d742f64412359d88c3dbd97356b088e 788 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 4 787 0.0 T 12-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 MIM_c19510 6d742f64412359d88c3dbd97356b088e 788 SUPERFAMILY SSF52009 346 466 2.22E-34 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 MIM_c19510 6d742f64412359d88c3dbd97356b088e 788 PIRSF PIRSF000854 1 788 0.0 T 12-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 MIM_c19510 6d742f64412359d88c3dbd97356b088e 788 Pfam PF00391 PEP-utilising enzyme, mobile domain 383 454 9.0E-26 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MIM_c19510 6d742f64412359d88c3dbd97356b088e 788 Gene3D G3DSA:3.30.1490.20 1 190 6.8E-71 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MIM_c19510 6d742f64412359d88c3dbd97356b088e 788 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 16 347 1.2E-114 T 12-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 MIM_c19510 6d742f64412359d88c3dbd97356b088e 788 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 693 711 - T 12-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 MIM_c28780 becc89af9ee53f7c7ad0b78ec8e60f7b 310 Gene3D G3DSA:3.90.110.10 148 309 2.2E-42 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 MIM_c28780 becc89af9ee53f7c7ad0b78ec8e60f7b 310 SUPERFAMILY SSF56327 146 308 4.04E-37 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 MIM_c28780 becc89af9ee53f7c7ad0b78ec8e60f7b 310 PIRSF PIRSF000102 1 310 2.7E-66 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MIM_c28780 becc89af9ee53f7c7ad0b78ec8e60f7b 310 Gene3D G3DSA:3.40.50.720 1 147 2.7E-35 T 12-10-2018 MIM_c28780 becc89af9ee53f7c7ad0b78ec8e60f7b 310 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 1 139 3.9E-22 T 12-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c28780 becc89af9ee53f7c7ad0b78ec8e60f7b 310 PRINTS PR00086 L-lactate dehydrogenase signature 143 161 3.3E-22 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MIM_c28780 becc89af9ee53f7c7ad0b78ec8e60f7b 310 PRINTS PR00086 L-lactate dehydrogenase signature 27 51 3.3E-22 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MIM_c28780 becc89af9ee53f7c7ad0b78ec8e60f7b 310 PRINTS PR00086 L-lactate dehydrogenase signature 2 26 3.3E-22 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MIM_c28780 becc89af9ee53f7c7ad0b78ec8e60f7b 310 PRINTS PR00086 L-lactate dehydrogenase signature 121 141 3.3E-22 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MIM_c28780 becc89af9ee53f7c7ad0b78ec8e60f7b 310 PRINTS PR00086 L-lactate dehydrogenase signature 173 186 3.3E-22 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MIM_c28780 becc89af9ee53f7c7ad0b78ec8e60f7b 310 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 148 307 1.0E-16 T 12-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 MIM_c28780 becc89af9ee53f7c7ad0b78ec8e60f7b 310 SUPERFAMILY SSF51735 2 139 3.42E-26 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c39070 bd7385c20cb9d8d35111ee793b4ff6a2 179 Gene3D G3DSA:3.30.1440.10 1 179 5.4E-77 T 12-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39070 bd7385c20cb9d8d35111ee793b4ff6a2 179 Pfam PF00281 Ribosomal protein L5 26 80 1.1E-25 T 12-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39070 bd7385c20cb9d8d35111ee793b4ff6a2 179 PIRSF PIRSF002161 1 179 4.4E-62 T 12-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39070 bd7385c20cb9d8d35111ee793b4ff6a2 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 12-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39070 bd7385c20cb9d8d35111ee793b4ff6a2 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 43.293 T 12-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c39070 bd7385c20cb9d8d35111ee793b4ff6a2 179 SUPERFAMILY SSF55282 3 179 1.27E-75 T 12-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39070 bd7385c20cb9d8d35111ee793b4ff6a2 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 2.6E-40 T 12-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c09340 114be5628c03dafc50688130b5d13316 619 SUPERFAMILY SSF52016 424 615 6.59E-60 T 12-10-2018 MIM_c09340 114be5628c03dafc50688130b5d13316 619 Pfam PF00920 Dehydratase family 34 610 1.5E-215 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MIM_c09340 114be5628c03dafc50688130b5d13316 619 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 512 523 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MIM_c09340 114be5628c03dafc50688130b5d13316 619 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 613 7.8E-251 T 12-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MIM_c09340 114be5628c03dafc50688130b5d13316 619 Gene3D G3DSA:3.50.30.80 424 575 2.0E-54 T 12-10-2018 MIM_c09340 114be5628c03dafc50688130b5d13316 619 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 613 44.28 T 12-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MIM_c09340 114be5628c03dafc50688130b5d13316 619 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MIM_c09340 114be5628c03dafc50688130b5d13316 619 SUPERFAMILY SSF143975 4 423 3.27E-130 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MIM_c30050 ced6f49ba86b69f4b7b379aef2eb30c2 192 SUPERFAMILY SSF52317 1 186 1.21E-51 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c30050 ced6f49ba86b69f4b7b379aef2eb30c2 192 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 4 187 2.9E-55 T 12-10-2018 IPR006286 Deglycase PfpI MIM_c30050 ced6f49ba86b69f4b7b379aef2eb30c2 192 Gene3D G3DSA:3.40.50.880 1 191 5.6E-53 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c30050 ced6f49ba86b69f4b7b379aef2eb30c2 192 Pfam PF01965 DJ-1/PfpI family 3 184 8.7E-50 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 MIM_c00160 c9da9db4d07fccad7f7ec06d828d94f1 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c00160 c9da9db4d07fccad7f7ec06d828d94f1 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 246 1.7E-61 T 12-10-2018 MIM_c00160 c9da9db4d07fccad7f7ec06d828d94f1 249 SUPERFAMILY SSF51735 6 246 6.18E-79 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c00160 c9da9db4d07fccad7f7ec06d828d94f1 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 181 4.5E-4 T 12-10-2018 MIM_c00160 c9da9db4d07fccad7f7ec06d828d94f1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.0E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c00160 c9da9db4d07fccad7f7ec06d828d94f1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.0E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c00160 c9da9db4d07fccad7f7ec06d828d94f1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.0E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c00160 c9da9db4d07fccad7f7ec06d828d94f1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.0E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c00160 c9da9db4d07fccad7f7ec06d828d94f1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.0E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c00160 c9da9db4d07fccad7f7ec06d828d94f1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.0E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c00160 c9da9db4d07fccad7f7ec06d828d94f1 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 2.0E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c00160 c9da9db4d07fccad7f7ec06d828d94f1 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.0E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c00160 c9da9db4d07fccad7f7ec06d828d94f1 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 2.0E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c00160 c9da9db4d07fccad7f7ec06d828d94f1 249 Gene3D G3DSA:3.40.50.720 1 248 1.3E-82 T 12-10-2018 MIM_c20890 f2149317293c03bb723de575201f067d 262 Gene3D G3DSA:1.10.12.10 204 262 1.0E-16 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MIM_c20890 f2149317293c03bb723de575201f067d 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 261 4.9E-64 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c20890 f2149317293c03bb723de575201f067d 262 Gene3D G3DSA:3.90.226.10 1 203 6.8E-70 T 12-10-2018 MIM_c20890 f2149317293c03bb723de575201f067d 262 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 103 123 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 MIM_c20890 f2149317293c03bb723de575201f067d 262 SUPERFAMILY SSF52096 2 262 7.19E-85 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c03000 930934a8441a43f6e8c4ef90ef085103 527 Gene3D G3DSA:3.40.640.10 209 426 4.6E-76 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c03000 930934a8441a43f6e8c4ef90ef085103 527 SUPERFAMILY SSF53383 188 525 3.63E-74 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c03000 930934a8441a43f6e8c4ef90ef085103 527 SMART SM00345 81 140 3.4E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c03000 930934a8441a43f6e8c4ef90ef085103 527 Gene3D G3DSA:1.10.10.10 71 141 1.9E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c03000 930934a8441a43f6e8c4ef90ef085103 527 Gene3D G3DSA:3.90.1150.10 184 514 4.6E-76 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c03000 930934a8441a43f6e8c4ef90ef085103 527 Pfam PF00392 Bacterial regulatory proteins, gntR family 79 140 2.6E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c03000 930934a8441a43f6e8c4ef90ef085103 527 Pfam PF00155 Aminotransferase class I and II 175 513 5.5E-37 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MIM_c03000 930934a8441a43f6e8c4ef90ef085103 527 SUPERFAMILY SSF46785 73 150 2.4E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c39160 e79c2fccff38aea5548a601842e523b0 265 Pfam PF05013 N-formylglutamate amidohydrolase 14 232 4.3E-62 T 12-10-2018 IPR007709 N-formylglutamate amidohydrolase MIM_c39160 e79c2fccff38aea5548a601842e523b0 265 TIGRFAM TIGR02017 hutG_amidohyd: N-formylglutamate deformylase 6 264 9.6E-102 T 12-10-2018 IPR010247 N-formylglutamate deformylase MIM_c39160 e79c2fccff38aea5548a601842e523b0 265 SUPERFAMILY SSF53187 5 261 8.79E-73 T 12-10-2018 MIM_c39160 e79c2fccff38aea5548a601842e523b0 265 Gene3D G3DSA:3.40.630.40 2 263 1.3E-69 T 12-10-2018 MIM_c21150 825ed0aad8a603825e5574f1f775033c 995 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 61 113 2.9E-8 T 12-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c21150 825ed0aad8a603825e5574f1f775033c 995 Pfam PF13244 Domain of unknown function (DUF4040) 613 678 5.1E-21 T 12-10-2018 IPR025383 Domain of unknown function DUF4040 MIM_c21150 825ed0aad8a603825e5574f1f775033c 995 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 103 123 2.0E-40 T 12-10-2018 MIM_c21150 825ed0aad8a603825e5574f1f775033c 995 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 415 434 2.0E-40 T 12-10-2018 MIM_c21150 825ed0aad8a603825e5574f1f775033c 995 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 75 100 2.0E-40 T 12-10-2018 MIM_c21150 825ed0aad8a603825e5574f1f775033c 995 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 238 264 2.0E-40 T 12-10-2018 MIM_c21150 825ed0aad8a603825e5574f1f775033c 995 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 150 171 2.0E-40 T 12-10-2018 MIM_c21150 825ed0aad8a603825e5574f1f775033c 995 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 216 237 2.0E-40 T 12-10-2018 MIM_c21150 825ed0aad8a603825e5574f1f775033c 995 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 306 318 2.0E-40 T 12-10-2018 MIM_c21150 825ed0aad8a603825e5574f1f775033c 995 Pfam PF00361 Proton-conducting membrane transporter 126 400 1.8E-65 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c21150 825ed0aad8a603825e5574f1f775033c 995 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 815 936 2.5E-29 T 12-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein MIM_c33790 fed674e154481a3beb03675722fe1eaf 882 Pfam PF09937 Uncharacterized protein conserved in bacteria (DUF2169) 23 301 1.3E-66 T 12-10-2018 IPR018683 Domain of unknown function DUF2169 MIM_c33790 fed674e154481a3beb03675722fe1eaf 882 Pfam PF13599 Pentapeptide repeats (9 copies) 557 623 1.3E-10 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c33790 fed674e154481a3beb03675722fe1eaf 882 Pfam PF13599 Pentapeptide repeats (9 copies) 677 738 1.2E-6 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c33790 fed674e154481a3beb03675722fe1eaf 882 SUPERFAMILY SSF141571 554 658 7.98E-22 T 12-10-2018 MIM_c33790 fed674e154481a3beb03675722fe1eaf 882 Gene3D G3DSA:2.160.20.80 509 647 1.9E-20 T 12-10-2018 MIM_c33790 fed674e154481a3beb03675722fe1eaf 882 SUPERFAMILY SSF141571 716 848 3.27E-23 T 12-10-2018 MIM_c33790 fed674e154481a3beb03675722fe1eaf 882 Pfam PF00805 Pentapeptide repeats (8 copies) 802 835 2.4E-7 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c33790 fed674e154481a3beb03675722fe1eaf 882 Pfam PF00805 Pentapeptide repeats (8 copies) 759 796 6.9E-5 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c33790 fed674e154481a3beb03675722fe1eaf 882 Gene3D G3DSA:2.160.20.80 664 866 5.9E-27 T 12-10-2018 MIM_c11710 afcfc74fa8772187a6846b48f0b434c3 388 Gene3D G3DSA:3.20.20.120 128 387 1.5E-66 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MIM_c11710 afcfc74fa8772187a6846b48f0b434c3 388 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 10 134 1.1E-4 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain MIM_c11710 afcfc74fa8772187a6846b48f0b434c3 388 SMART SM00922 162 259 7.7E-16 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MIM_c11710 afcfc74fa8772187a6846b48f0b434c3 388 SUPERFAMILY SSF51604 123 380 4.98E-55 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MIM_c11710 afcfc74fa8772187a6846b48f0b434c3 388 Gene3D G3DSA:3.30.390.10 1 127 6.7E-68 T 12-10-2018 IPR029017 Enolase-like, N-terminal MIM_c11710 afcfc74fa8772187a6846b48f0b434c3 388 SUPERFAMILY SSF54826 1 138 2.25E-29 T 12-10-2018 MIM_c11710 afcfc74fa8772187a6846b48f0b434c3 388 Pfam PF13378 Enolase C-terminal domain-like 165 376 4.4E-42 T 12-10-2018 IPR029065 Enolase C-terminal domain-like MIM_c39350 d098dbc7b106b802e2d50c61641dc0ed 171 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 13 169 1.5E-12 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like MIM_c39350 d098dbc7b106b802e2d50c61641dc0ed 171 Gene3D G3DSA:3.30.530.20 3 171 4.1E-31 T 12-10-2018 IPR023393 START-like domain superfamily MIM_c39350 d098dbc7b106b802e2d50c61641dc0ed 171 SUPERFAMILY SSF55961 2 170 3.34E-28 T 12-10-2018 MIM_c11470 69467c82f3059347a2b77e1795dc5259 263 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 1 122 2.2E-36 T 12-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MIM_c11470 69467c82f3059347a2b77e1795dc5259 263 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 1 262 33.232 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MIM_c11470 69467c82f3059347a2b77e1795dc5259 263 SUPERFAMILY SSF51735 1 262 4.16E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c11470 69467c82f3059347a2b77e1795dc5259 263 PIRSF PIRSF000161 1 263 4.7E-83 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MIM_c11470 69467c82f3059347a2b77e1795dc5259 263 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 125 261 2.3E-40 T 12-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MIM_c11470 69467c82f3059347a2b77e1795dc5259 263 SUPERFAMILY SSF55347 124 233 1.0E-34 T 12-10-2018 MIM_c11470 69467c82f3059347a2b77e1795dc5259 263 Gene3D G3DSA:3.40.50.720 2 260 4.2E-96 T 12-10-2018 MIM_c11470 69467c82f3059347a2b77e1795dc5259 263 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 1 262 1.1E-88 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MIM_c11470 69467c82f3059347a2b77e1795dc5259 263 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 147 164 - T 12-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MIM_c11470 69467c82f3059347a2b77e1795dc5259 263 Gene3D G3DSA:3.30.360.10 124 231 4.2E-96 T 12-10-2018 MIM_c18890 95648307f53c5fa087ef1083a78eee47 297 Gene3D G3DSA:2.60.120.10 3 243 1.7E-56 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c18890 95648307f53c5fa087ef1083a78eee47 297 PIRSF PIRSF006232 1 281 2.0E-65 T 12-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 MIM_c18890 95648307f53c5fa087ef1083a78eee47 297 Pfam PF02678 Pirin 18 118 6.7E-27 T 12-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 MIM_c18890 95648307f53c5fa087ef1083a78eee47 297 Pfam PF05726 Pirin C-terminal cupin domain 170 267 5.0E-13 T 12-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 MIM_c18890 95648307f53c5fa087ef1083a78eee47 297 SUPERFAMILY SSF51182 9 274 1.38E-59 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c16140 9f66e06c28a58411127792ed021c6c5c 391 Pfam PF03060 Nitronate monooxygenase 16 299 6.6E-32 T 12-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 MIM_c16140 9f66e06c28a58411127792ed021c6c5c 391 SUPERFAMILY SSF51412 4 317 1.98E-31 T 12-10-2018 MIM_c16140 9f66e06c28a58411127792ed021c6c5c 391 Gene3D G3DSA:3.20.20.70 12 388 3.3E-46 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c18530 f078acfe28ea13045db034333dc9bf8c 403 TIGRFAM TIGR02006 IscS: cysteine desulfurase IscS 2 403 7.5E-228 T 12-10-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 MIM_c18530 f078acfe28ea13045db034333dc9bf8c 403 Gene3D G3DSA:3.40.640.10 17 261 1.4E-162 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c18530 f078acfe28ea13045db034333dc9bf8c 403 PIRSF PIRSF005572 3 383 1.1E-134 T 12-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 MIM_c18530 f078acfe28ea13045db034333dc9bf8c 403 SUPERFAMILY SSF53383 6 390 4.92E-111 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c18530 f078acfe28ea13045db034333dc9bf8c 403 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 2 394 54.607 T 12-10-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 MIM_c18530 f078acfe28ea13045db034333dc9bf8c 403 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 196 215 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MIM_c18530 f078acfe28ea13045db034333dc9bf8c 403 Gene3D G3DSA:3.90.1150.10 6 374 1.4E-162 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c18530 f078acfe28ea13045db034333dc9bf8c 403 Pfam PF00266 Aminotransferase class-V 6 367 1.7E-86 T 12-10-2018 IPR000192 Aminotransferase class V domain MIM_c13340 c490302695945ac5248508ba30ab2296 412 Gene3D G3DSA:3.30.559.10 180 412 7.4E-93 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MIM_c13340 c490302695945ac5248508ba30ab2296 412 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 4 411 4.8E-170 T 12-10-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 MIM_c13340 c490302695945ac5248508ba30ab2296 412 SUPERFAMILY SSF52777 182 411 2.0E-86 T 12-10-2018 MIM_c13340 c490302695945ac5248508ba30ab2296 412 Gene3D G3DSA:2.40.50.100 2 106 1.4E-22 T 12-10-2018 MIM_c13340 c490302695945ac5248508ba30ab2296 412 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MIM_c13340 c490302695945ac5248508ba30ab2296 412 SUPERFAMILY SSF47005 116 159 2.09E-8 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MIM_c13340 c490302695945ac5248508ba30ab2296 412 Pfam PF02817 e3 binding domain 124 155 7.1E-11 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 MIM_c13340 c490302695945ac5248508ba30ab2296 412 Pfam PF00364 Biotin-requiring enzyme 5 77 1.5E-20 T 12-10-2018 IPR000089 Biotin/lipoyl attachment MIM_c13340 c490302695945ac5248508ba30ab2296 412 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 182 410 1.1E-79 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 MIM_c13340 c490302695945ac5248508ba30ab2296 412 Gene3D G3DSA:4.10.320.10 118 164 1.0E-9 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MIM_c13340 c490302695945ac5248508ba30ab2296 412 SUPERFAMILY SSF51230 2 97 1.13E-26 T 12-10-2018 IPR011053 Single hybrid motif MIM_c35690 d1e404ad226c108e7267d438ff99e12b 876 Gene3D G3DSA:2.160.20.80 532 661 6.6E-22 T 12-10-2018 MIM_c35690 d1e404ad226c108e7267d438ff99e12b 876 SUPERFAMILY SSF141571 739 844 1.15E-22 T 12-10-2018 MIM_c35690 d1e404ad226c108e7267d438ff99e12b 876 Gene3D G3DSA:2.160.20.100 662 736 2.9E-5 T 12-10-2018 MIM_c35690 d1e404ad226c108e7267d438ff99e12b 876 Pfam PF13599 Pentapeptide repeats (9 copies) 742 809 5.2E-9 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c35690 d1e404ad226c108e7267d438ff99e12b 876 Pfam PF13599 Pentapeptide repeats (9 copies) 555 631 3.4E-11 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c35690 d1e404ad226c108e7267d438ff99e12b 876 Pfam PF00805 Pentapeptide repeats (8 copies) 810 840 1.1E-5 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c35690 d1e404ad226c108e7267d438ff99e12b 876 Pfam PF09937 Uncharacterized protein conserved in bacteria (DUF2169) 60 301 2.4E-64 T 12-10-2018 IPR018683 Domain of unknown function DUF2169 MIM_c35690 d1e404ad226c108e7267d438ff99e12b 876 SUPERFAMILY SSF141571 550 652 1.57E-20 T 12-10-2018 MIM_c35690 d1e404ad226c108e7267d438ff99e12b 876 SUPERFAMILY SSF141571 662 732 3.92E-6 T 12-10-2018 MIM_c35690 d1e404ad226c108e7267d438ff99e12b 876 Gene3D G3DSA:2.160.20.100 737 859 3.3E-22 T 12-10-2018 MIM_c21890 2cea895020b77ce0d99dbcb9223aadad 408 ProSitePatterns PS01219 Ammonium transporters signature. 161 186 - T 12-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 MIM_c21890 2cea895020b77ce0d99dbcb9223aadad 408 Pfam PF00909 Ammonium Transporter Family 7 406 2.1E-119 T 12-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 MIM_c21890 2cea895020b77ce0d99dbcb9223aadad 408 TIGRFAM TIGR00836 amt: ammonium transporter 5 406 2.7E-132 T 12-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 MIM_c21890 2cea895020b77ce0d99dbcb9223aadad 408 Gene3D G3DSA:1.10.3430.10 1 408 4.2E-138 T 12-10-2018 IPR029020 Ammonium/urea transporter MIM_c21890 2cea895020b77ce0d99dbcb9223aadad 408 SUPERFAMILY SSF111352 2 383 6.41E-123 T 12-10-2018 MIM_c15150 6f6003ee8279951698b8e5262996dded 90 Pfam PF04362 Bacterial Fe(2+) trafficking 1 88 2.3E-40 T 12-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 MIM_c15150 6f6003ee8279951698b8e5262996dded 90 SUPERFAMILY SSF111148 1 89 4.84E-37 T 12-10-2018 IPR036766 Fe(II) trafficking protein YggX superfamily GO:0005506 MIM_c15150 6f6003ee8279951698b8e5262996dded 90 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 1 76 1.0E-31 T 12-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 MIM_c15150 6f6003ee8279951698b8e5262996dded 90 PIRSF PIRSF029827 1 90 1.0E-39 T 12-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 MIM_c15150 6f6003ee8279951698b8e5262996dded 90 Gene3D G3DSA:1.10.3880.10 1 90 1.1E-37 T 12-10-2018 IPR036766 Fe(II) trafficking protein YggX superfamily GO:0005506 MIM_c15150 6f6003ee8279951698b8e5262996dded 90 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 1 88 27.717 T 12-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 MIM_c24670 8adf8f7dc15037ff36b0d29a1dc4e802 325 Pfam PF00107 Zinc-binding dehydrogenase 151 266 2.3E-33 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MIM_c24670 8adf8f7dc15037ff36b0d29a1dc4e802 325 SUPERFAMILY SSF50129 1 137 3.35E-37 T 12-10-2018 IPR011032 GroES-like superfamily MIM_c24670 8adf8f7dc15037ff36b0d29a1dc4e802 325 Gene3D G3DSA:3.90.180.10 13 323 2.7E-107 T 12-10-2018 MIM_c24670 8adf8f7dc15037ff36b0d29a1dc4e802 325 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 325 6.9E-149 T 12-10-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 MIM_c24670 8adf8f7dc15037ff36b0d29a1dc4e802 325 Gene3D G3DSA:3.40.50.720 120 262 2.7E-107 T 12-10-2018 MIM_c24670 8adf8f7dc15037ff36b0d29a1dc4e802 325 SUPERFAMILY SSF51735 111 287 1.32E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c24670 8adf8f7dc15037ff36b0d29a1dc4e802 325 SMART SM00829 10 323 8.6E-58 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MIM_c24670 8adf8f7dc15037ff36b0d29a1dc4e802 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 2.7E-7 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MIM_c03730 67f71536b0a145dfb44ffad414bdd736 118 PIRSF PIRSF031804 2 118 3.5E-35 T 12-10-2018 IPR016983 Uncharacterised conserved protein UCP031804 MIM_c03730 67f71536b0a145dfb44ffad414bdd736 118 Pfam PF06803 Protein of unknown function (DUF1232) 57 90 1.6E-13 T 12-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 MIM_c39580 a1f6f48ffd53ba0aab6b226cdf18f0cf 477 Pfam PF02913 FAD linked oxidases, C-terminal domain 229 469 9.7E-67 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 MIM_c39580 a1f6f48ffd53ba0aab6b226cdf18f0cf 477 Pfam PF01565 FAD binding domain 55 192 3.3E-41 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MIM_c39580 a1f6f48ffd53ba0aab6b226cdf18f0cf 477 Gene3D G3DSA:3.30.465.40 26 245 2.5E-73 T 12-10-2018 MIM_c39580 a1f6f48ffd53ba0aab6b226cdf18f0cf 477 Gene3D G3DSA:3.30.70.2740 347 429 1.1E-12 T 12-10-2018 MIM_c39580 a1f6f48ffd53ba0aab6b226cdf18f0cf 477 SUPERFAMILY SSF55103 232 472 1.34E-71 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MIM_c39580 a1f6f48ffd53ba0aab6b226cdf18f0cf 477 Gene3D G3DSA:1.10.45.10 430 470 1.1E-13 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 MIM_c39580 a1f6f48ffd53ba0aab6b226cdf18f0cf 477 SUPERFAMILY SSF56176 12 229 4.67E-71 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MIM_c39860 4b43c322e11c00b1373eaaebf7b3d42d 274 Gene3D G3DSA:3.40.50.300 1 268 2.8E-60 T 12-10-2018 MIM_c39860 4b43c322e11c00b1373eaaebf7b3d42d 274 Pfam PF00005 ABC transporter 27 197 1.5E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c39860 4b43c322e11c00b1373eaaebf7b3d42d 274 SUPERFAMILY SSF52540 4 258 5.52E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c39860 4b43c322e11c00b1373eaaebf7b3d42d 274 SMART SM00382 35 247 8.4E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c39860 4b43c322e11c00b1373eaaebf7b3d42d 274 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 252 269 4.6E-5 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal MIM_c05300 ff84f8f29312efa538627f4bb4c10f53 324 SUPERFAMILY SSF161111 12 225 2.35E-39 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily MIM_c05300 ff84f8f29312efa538627f4bb4c10f53 324 Gene3D G3DSA:3.30.70.1350 226 306 4.9E-5 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 MIM_c05300 ff84f8f29312efa538627f4bb4c10f53 324 Gene3D G3DSA:1.20.1510.10 13 223 2.0E-35 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily MIM_c05300 ff84f8f29312efa538627f4bb4c10f53 324 SUPERFAMILY SSF160240 228 303 7.19E-7 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 MIM_c05300 ff84f8f29312efa538627f4bb4c10f53 324 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 15 307 1.6E-39 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MIM_c05300 ff84f8f29312efa538627f4bb4c10f53 324 Pfam PF01545 Cation efflux family 17 220 1.1E-33 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MIM_c12610 f7d5ebbb5cd5b8c7467de23bc4ae6c93 339 Pfam PF09179 TilS substrate binding domain 263 330 4.6E-11 T 12-10-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MIM_c12610 f7d5ebbb5cd5b8c7467de23bc4ae6c93 339 SUPERFAMILY SSF82829 253 333 1.83E-14 T 12-10-2018 MIM_c12610 f7d5ebbb5cd5b8c7467de23bc4ae6c93 339 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 28 215 1.8E-45 T 12-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MIM_c12610 f7d5ebbb5cd5b8c7467de23bc4ae6c93 339 Gene3D G3DSA:3.40.50.620 23 245 2.5E-63 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c12610 f7d5ebbb5cd5b8c7467de23bc4ae6c93 339 Pfam PF01171 PP-loop family 28 211 1.5E-48 T 12-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 MIM_c12610 f7d5ebbb5cd5b8c7467de23bc4ae6c93 339 Gene3D G3DSA:1.20.59.20 247 333 6.4E-6 T 12-10-2018 MIM_c12610 f7d5ebbb5cd5b8c7467de23bc4ae6c93 339 SUPERFAMILY SSF52402 28 244 6.28E-50 T 12-10-2018 MIM_c12610 f7d5ebbb5cd5b8c7467de23bc4ae6c93 339 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 16 324 21.034 T 12-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MIM_c29340 1d182531549c6e4f5e16b36ee98ec463 228 SUPERFAMILY SSF53474 20 226 2.47E-48 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c29340 1d182531549c6e4f5e16b36ee98ec463 228 Pfam PF02230 Phospholipase/Carboxylesterase 18 226 1.1E-49 T 12-10-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 MIM_c29340 1d182531549c6e4f5e16b36ee98ec463 228 Gene3D G3DSA:3.40.50.1820 11 228 3.1E-64 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c14260 e2d7eff7bdcf44d24a5f3a2397c22fa0 396 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 255 341 8.5E-8 T 12-10-2018 IPR023885 4Fe4S-binding SPASM domain MIM_c14260 e2d7eff7bdcf44d24a5f3a2397c22fa0 396 Pfam PF13186 Iron-sulfur cluster-binding domain 248 314 1.8E-8 T 12-10-2018 IPR023885 4Fe4S-binding SPASM domain MIM_c14260 e2d7eff7bdcf44d24a5f3a2397c22fa0 396 PIRSF PIRSF037420 4 360 4.8E-114 T 12-10-2018 IPR017200 Coenzyme PQQ synthesis protein E MIM_c14260 e2d7eff7bdcf44d24a5f3a2397c22fa0 396 Pfam PF04055 Radical SAM superfamily 25 179 3.4E-21 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MIM_c14260 e2d7eff7bdcf44d24a5f3a2397c22fa0 396 TIGRFAM TIGR02109 PQQ_syn_pqqE: coenzyme PQQ biosynthesis enzyme PqqE 14 369 4.8E-161 T 12-10-2018 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 MIM_c14260 e2d7eff7bdcf44d24a5f3a2397c22fa0 396 SUPERFAMILY SSF102114 17 323 1.27E-70 T 12-10-2018 MIM_c14260 e2d7eff7bdcf44d24a5f3a2397c22fa0 396 Gene3D G3DSA:3.20.20.70 20 298 2.1E-42 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c14260 e2d7eff7bdcf44d24a5f3a2397c22fa0 396 Hamap MF_00660 Coenzyme PQQ synthesis protein E [pqqE]. 1 382 181.194 T 12-10-2018 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 MIM_c14260 e2d7eff7bdcf44d24a5f3a2397c22fa0 396 Pfam PF13394 4Fe-4S single cluster domain 28 85 6.2E-8 T 12-10-2018 MIM_c15090 db2d1e00c9df63a53cb2d2df30e0ddec 374 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 47 372 1.9E-123 T 12-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 MIM_c15090 db2d1e00c9df63a53cb2d2df30e0ddec 374 SUPERFAMILY SSF52540 17 256 9.2E-86 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c15090 db2d1e00c9df63a53cb2d2df30e0ddec 374 Gene3D G3DSA:2.40.50.940 235 298 1.7E-11 T 12-10-2018 MIM_c15090 db2d1e00c9df63a53cb2d2df30e0ddec 374 Gene3D G3DSA:3.40.50.300 17 234 2.1E-66 T 12-10-2018 MIM_c15090 db2d1e00c9df63a53cb2d2df30e0ddec 374 Gene3D G3DSA:2.40.50.140 299 346 1.7E-11 T 12-10-2018 MIM_c15090 db2d1e00c9df63a53cb2d2df30e0ddec 374 SMART SM00382 41 230 2.1E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c15090 db2d1e00c9df63a53cb2d2df30e0ddec 374 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c15090 db2d1e00c9df63a53cb2d2df30e0ddec 374 Pfam PF00005 ABC transporter 33 174 2.7E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c15090 db2d1e00c9df63a53cb2d2df30e0ddec 374 Pfam PF08402 TOBE domain 292 372 1.4E-14 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 MIM_c15090 db2d1e00c9df63a53cb2d2df30e0ddec 374 SUPERFAMILY SSF50331 250 372 6.23E-15 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MIM_c32020 320603359302170f982a0c4efb465c1e 548 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 521 1.4E-100 T 12-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 MIM_c32020 320603359302170f982a0c4efb465c1e 548 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 12-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MIM_c32020 320603359302170f982a0c4efb465c1e 548 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 526 6.9E-256 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MIM_c32020 320603359302170f982a0c4efb465c1e 548 Gene3D G3DSA:3.30.260.10 136 410 8.9E-239 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily MIM_c32020 320603359302170f982a0c4efb465c1e 548 PRINTS PR00298 60kDa chaperonin signature 83 110 9.1E-75 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MIM_c32020 320603359302170f982a0c4efb465c1e 548 PRINTS PR00298 60kDa chaperonin signature 398 419 9.1E-75 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MIM_c32020 320603359302170f982a0c4efb465c1e 548 PRINTS PR00298 60kDa chaperonin signature 27 53 9.1E-75 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MIM_c32020 320603359302170f982a0c4efb465c1e 548 PRINTS PR00298 60kDa chaperonin signature 268 291 9.1E-75 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MIM_c32020 320603359302170f982a0c4efb465c1e 548 PRINTS PR00298 60kDa chaperonin signature 350 375 9.1E-75 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MIM_c32020 320603359302170f982a0c4efb465c1e 548 Gene3D G3DSA:3.50.7.10 192 372 8.9E-239 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily MIM_c32020 320603359302170f982a0c4efb465c1e 548 Hamap MF_00600 60 kDa chaperonin [groL]. 2 545 41.401 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MIM_c32020 320603359302170f982a0c4efb465c1e 548 Gene3D G3DSA:1.10.560.10 8 521 8.9E-239 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily MIM_c32020 320603359302170f982a0c4efb465c1e 548 SUPERFAMILY SSF54849 137 203 5.95E-25 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily MIM_c32020 320603359302170f982a0c4efb465c1e 548 SUPERFAMILY SSF48592 7 521 6.41E-78 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily MIM_c32020 320603359302170f982a0c4efb465c1e 548 SUPERFAMILY SSF52029 184 376 3.29E-83 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily MIM_c10900 8063d996a9f7a7a7836718ce103bb985 154 Gene3D G3DSA:3.40.50.150 3 137 4.8E-13 T 12-10-2018 MIM_c10900 8063d996a9f7a7a7836718ce103bb985 154 SUPERFAMILY SSF53335 7 131 2.35E-14 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c18570 492719329400206d0d88ae20e0f60c35 620 Gene3D G3DSA:3.30.420.40 192 363 9.7E-109 T 12-10-2018 MIM_c18570 492719329400206d0d88ae20e0f60c35 620 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 24 31 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MIM_c18570 492719329400206d0d88ae20e0f60c35 620 Gene3D G3DSA:1.20.1270.10 524 618 1.1E-24 T 12-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 MIM_c18570 492719329400206d0d88ae20e0f60c35 620 SUPERFAMILY SSF100920 387 536 1.44E-49 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 MIM_c18570 492719329400206d0d88ae20e0f60c35 620 TIGRFAM TIGR01991 HscA: Fe-S protein assembly chaperone HscA 21 617 8.2E-266 T 12-10-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 MIM_c18570 492719329400206d0d88ae20e0f60c35 620 SUPERFAMILY SSF100934 507 618 9.61E-31 T 12-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 MIM_c18570 492719329400206d0d88ae20e0f60c35 620 PRINTS PR00301 70kDa heat shock protein signature 209 219 4.3E-54 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MIM_c18570 492719329400206d0d88ae20e0f60c35 620 PRINTS PR00301 70kDa heat shock protein signature 388 407 4.3E-54 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MIM_c18570 492719329400206d0d88ae20e0f60c35 620 PRINTS PR00301 70kDa heat shock protein signature 48 60 4.3E-54 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MIM_c18570 492719329400206d0d88ae20e0f60c35 620 PRINTS PR00301 70kDa heat shock protein signature 331 347 4.3E-54 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MIM_c18570 492719329400206d0d88ae20e0f60c35 620 PRINTS PR00301 70kDa heat shock protein signature 150 170 4.3E-54 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MIM_c18570 492719329400206d0d88ae20e0f60c35 620 PRINTS PR00301 70kDa heat shock protein signature 469 485 4.3E-54 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MIM_c18570 492719329400206d0d88ae20e0f60c35 620 PRINTS PR00301 70kDa heat shock protein signature 362 382 4.3E-54 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MIM_c18570 492719329400206d0d88ae20e0f60c35 620 PRINTS PR00301 70kDa heat shock protein signature 20 33 4.3E-54 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MIM_c18570 492719329400206d0d88ae20e0f60c35 620 Gene3D G3DSA:2.60.34.10 382 523 4.2E-51 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 MIM_c18570 492719329400206d0d88ae20e0f60c35 620 Gene3D G3DSA:3.30.420.40 22 376 9.7E-109 T 12-10-2018 MIM_c18570 492719329400206d0d88ae20e0f60c35 620 Gene3D G3DSA:3.90.640.10 236 313 9.7E-109 T 12-10-2018 MIM_c18570 492719329400206d0d88ae20e0f60c35 620 Pfam PF00012 Hsp70 protein 21 602 2.3E-177 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MIM_c18570 492719329400206d0d88ae20e0f60c35 620 Hamap MF_00679 Chaperone protein HscA [hscA]. 1 619 41.832 T 12-10-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 MIM_c18570 492719329400206d0d88ae20e0f60c35 620 SUPERFAMILY SSF53067 198 378 4.76E-47 T 12-10-2018 MIM_c18570 492719329400206d0d88ae20e0f60c35 620 SUPERFAMILY SSF53067 19 194 1.68E-51 T 12-10-2018 MIM_c18570 492719329400206d0d88ae20e0f60c35 620 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 203 216 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MIM_c13080 134de7db86510f59944940d8ba111fd2 161 Pfam PF04461 Protein of unknown function (DUF520) 2 160 3.6E-64 T 12-10-2018 IPR007551 Protein of unknown function DUF520 MIM_c13080 134de7db86510f59944940d8ba111fd2 161 Gene3D G3DSA:3.30.70.990 9 98 1.9E-57 T 12-10-2018 IPR035570 UPF0234, N-terminal MIM_c13080 134de7db86510f59944940d8ba111fd2 161 SUPERFAMILY SSF89963 89 161 1.88E-25 T 12-10-2018 IPR036183 YajQ-like superfamily MIM_c13080 134de7db86510f59944940d8ba111fd2 161 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 1 161 27.282 T 12-10-2018 IPR007551 Protein of unknown function DUF520 MIM_c13080 134de7db86510f59944940d8ba111fd2 161 SUPERFAMILY SSF89963 2 87 1.65E-30 T 12-10-2018 IPR036183 YajQ-like superfamily MIM_c13080 134de7db86510f59944940d8ba111fd2 161 Gene3D G3DSA:3.30.70.860 3 160 1.9E-57 T 12-10-2018 IPR035571 UPF0234-like, C-terminal MIM_c01180 7df566426637ed44e175b00e1e25feaa 235 SMART SM00382 27 214 1.3E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c01180 7df566426637ed44e175b00e1e25feaa 235 Gene3D G3DSA:3.40.50.300 1 235 6.0E-61 T 12-10-2018 MIM_c01180 7df566426637ed44e175b00e1e25feaa 235 SUPERFAMILY SSF52540 2 233 1.33E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c01180 7df566426637ed44e175b00e1e25feaa 235 Pfam PF00005 ABC transporter 18 163 2.1E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c01180 7df566426637ed44e175b00e1e25feaa 235 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c31120 99c720cf0de7dc99e8006764553c21b3 957 SUPERFAMILY SSF46626 710 817 5.49E-14 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c31120 99c720cf0de7dc99e8006764553c21b3 957 Gene3D G3DSA:3.30.365.10 296 510 1.3E-16 T 12-10-2018 MIM_c31120 99c720cf0de7dc99e8006764553c21b3 957 SUPERFAMILY SSF46626 562 688 1.26E-22 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c31120 99c720cf0de7dc99e8006764553c21b3 957 SUPERFAMILY SSF56003 141 505 3.81E-27 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 MIM_c31120 99c720cf0de7dc99e8006764553c21b3 957 SMART SM01008 29 103 0.002 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MIM_c31120 99c720cf0de7dc99e8006764553c21b3 957 SUPERFAMILY SSF46626 836 943 2.55E-15 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c31120 99c720cf0de7dc99e8006764553c21b3 957 Pfam PF00034 Cytochrome c 566 665 3.9E-6 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c31120 99c720cf0de7dc99e8006764553c21b3 957 Gene3D G3DSA:3.30.365.10 141 216 3.2E-7 T 12-10-2018 MIM_c31120 99c720cf0de7dc99e8006764553c21b3 957 Gene3D G3DSA:1.10.760.10 686 829 1.2E-6 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c31120 99c720cf0de7dc99e8006764553c21b3 957 Gene3D G3DSA:1.10.760.10 518 673 7.0E-10 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c31120 99c720cf0de7dc99e8006764553c21b3 957 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 849 929 2.8E-7 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c31120 99c720cf0de7dc99e8006764553c21b3 957 SUPERFAMILY SSF54665 34 101 2.62E-6 T 12-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily MIM_c31120 99c720cf0de7dc99e8006764553c21b3 957 Gene3D G3DSA:1.10.760.10 830 956 1.8E-18 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c38270 3eaf50c3919ee865ad8ac2e61ed40853 267 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c38270 3eaf50c3919ee865ad8ac2e61ed40853 267 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 13 152 0.0089 T 12-10-2018 MIM_c38270 3eaf50c3919ee865ad8ac2e61ed40853 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.3E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38270 3eaf50c3919ee865ad8ac2e61ed40853 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 1.3E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38270 3eaf50c3919ee865ad8ac2e61ed40853 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 1.3E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38270 3eaf50c3919ee865ad8ac2e61ed40853 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.3E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38270 3eaf50c3919ee865ad8ac2e61ed40853 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.3E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38270 3eaf50c3919ee865ad8ac2e61ed40853 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.3E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38270 3eaf50c3919ee865ad8ac2e61ed40853 267 Gene3D G3DSA:3.40.50.720 3 265 5.1E-82 T 12-10-2018 MIM_c38270 3eaf50c3919ee865ad8ac2e61ed40853 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 1.6E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38270 3eaf50c3919ee865ad8ac2e61ed40853 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 1.6E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38270 3eaf50c3919ee865ad8ac2e61ed40853 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.6E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38270 3eaf50c3919ee865ad8ac2e61ed40853 267 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 253 2.1E-67 T 12-10-2018 MIM_c38270 3eaf50c3919ee865ad8ac2e61ed40853 267 SUPERFAMILY SSF51735 9 255 4.38E-79 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c31820 eac1741f5e44d05033b5e9b50825d5af 543 Pfam PF00732 GMC oxidoreductase 8 305 4.3E-80 T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c31820 eac1741f5e44d05033b5e9b50825d5af 543 SUPERFAMILY SSF54373 300 483 5.3E-58 T 12-10-2018 MIM_c31820 eac1741f5e44d05033b5e9b50825d5af 543 Gene3D G3DSA:3.30.560.10 46 478 1.2E-178 T 12-10-2018 MIM_c31820 eac1741f5e44d05033b5e9b50825d5af 543 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 85 108 - T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c31820 eac1741f5e44d05033b5e9b50825d5af 543 PIRSF PIRSF000137 1 543 4.8E-151 T 12-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c31820 eac1741f5e44d05033b5e9b50825d5af 543 SUPERFAMILY SSF51905 4 541 1.05E-86 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c31820 eac1741f5e44d05033b5e9b50825d5af 543 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 264 278 - T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c31820 eac1741f5e44d05033b5e9b50825d5af 543 Pfam PF05199 GMC oxidoreductase 397 535 3.9E-39 T 12-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 MIM_c31820 eac1741f5e44d05033b5e9b50825d5af 543 Gene3D G3DSA:3.50.50.60 8 539 1.2E-178 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c16280 048e9280e75943a6edef7016a766717a 685 SUPERFAMILY SSF52540 298 627 7.19E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c16280 048e9280e75943a6edef7016a766717a 685 Gene3D G3DSA:3.30.450.380 229 408 5.9E-37 T 12-10-2018 MIM_c16280 048e9280e75943a6edef7016a766717a 685 SMART SM00240 21 71 1.6E-6 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MIM_c16280 048e9280e75943a6edef7016a766717a 685 Gene3D G3DSA:2.60.200.20 6 95 1.9E-15 T 12-10-2018 MIM_c16280 048e9280e75943a6edef7016a766717a 685 SUPERFAMILY SSF49879 21 92 9.32E-18 T 12-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 MIM_c16280 048e9280e75943a6edef7016a766717a 685 Pfam PF00498 FHA domain 23 86 1.3E-12 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MIM_c16280 048e9280e75943a6edef7016a766717a 685 Gene3D G3DSA:3.40.50.300 414 630 3.5E-70 T 12-10-2018 MIM_c16280 048e9280e75943a6edef7016a766717a 685 Pfam PF00437 Type II/IV secretion system protein 314 590 3.0E-79 T 12-10-2018 IPR001482 Type II/IV secretion system protein MIM_c14280 9d01296cff760c0fc4321cb348c8712b 309 Hamap MF_00653 Coenzyme PQQ synthesis protein B [pqqB]. 1 309 160.542 T 12-10-2018 IPR011842 Coenzyme PQQ biosynthesis protein B MIM_c14280 9d01296cff760c0fc4321cb348c8712b 309 SUPERFAMILY SSF56281 1 309 4.77E-57 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MIM_c14280 9d01296cff760c0fc4321cb348c8712b 309 Gene3D G3DSA:3.60.15.10 1 309 6.6E-88 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MIM_c14280 9d01296cff760c0fc4321cb348c8712b 309 TIGRFAM TIGR02108 PQQ_syn_pqqB: coenzyme PQQ biosynthesis protein B 2 309 1.4E-121 T 12-10-2018 IPR011842 Coenzyme PQQ biosynthesis protein B MIM_c14280 9d01296cff760c0fc4321cb348c8712b 309 Pfam PF12706 Beta-lactamase superfamily domain 51 276 2.6E-44 T 12-10-2018 IPR001279 Metallo-beta-lactamase MIM_c26370 c28adb16cbf077282c3cb46903ff163f 164 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 87 98 - T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MIM_c26370 c28adb16cbf077282c3cb46903ff163f 164 SUPERFAMILY SSF55083 1 153 4.45E-51 T 12-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MIM_c26370 c28adb16cbf077282c3cb46903ff163f 164 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 132 3.6E-36 T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MIM_c26370 c28adb16cbf077282c3cb46903ff163f 164 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 132 1.1E-38 T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MIM_c26370 c28adb16cbf077282c3cb46903ff163f 164 Gene3D G3DSA:3.30.70.560 1 156 1.0E-50 T 12-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MIM_c16920 053a21a3c8eb675830742ed690dcc8ae 318 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 42 314 1.6E-83 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c16920 053a21a3c8eb675830742ed690dcc8ae 318 PIRSF PIRSF017082 3 318 3.4E-74 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c16920 053a21a3c8eb675830742ed690dcc8ae 318 Gene3D G3DSA:3.40.190.150 23 308 1.5E-104 T 12-10-2018 MIM_c16920 053a21a3c8eb675830742ed690dcc8ae 318 SUPERFAMILY SSF53850 109 281 4.29E-11 T 12-10-2018 MIM_c16920 053a21a3c8eb675830742ed690dcc8ae 318 Gene3D G3DSA:3.40.190.10 121 243 1.5E-104 T 12-10-2018 MIM_c35980 ad0f6350aed9593c61fce3f022d60eba 345 Gene3D G3DSA:1.10.260.40 1 61 1.0E-21 T 12-10-2018 MIM_c35980 ad0f6350aed9593c61fce3f022d60eba 345 SUPERFAMILY SSF53822 64 316 2.86E-59 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c35980 ad0f6350aed9593c61fce3f022d60eba 345 SMART SM00354 7 77 3.3E-30 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MIM_c35980 ad0f6350aed9593c61fce3f022d60eba 345 Gene3D G3DSA:3.40.50.2300 165 292 2.6E-65 T 12-10-2018 MIM_c35980 ad0f6350aed9593c61fce3f022d60eba 345 Pfam PF13377 Periplasmic binding protein-like domain 173 334 2.1E-29 T 12-10-2018 MIM_c35980 ad0f6350aed9593c61fce3f022d60eba 345 Gene3D G3DSA:3.40.50.2300 62 309 2.6E-65 T 12-10-2018 MIM_c35980 ad0f6350aed9593c61fce3f022d60eba 345 SUPERFAMILY SSF47413 7 65 4.69E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c35980 ad0f6350aed9593c61fce3f022d60eba 345 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 54 2.7E-16 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MIM_c21900 59ebbf95e240b4608ed6bc0dbe6d2fa0 585 Gene3D G3DSA:3.50.30.10 21 253 3.3E-66 T 12-10-2018 MIM_c21900 59ebbf95e240b4608ed6bc0dbe6d2fa0 585 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 17 566 3.0E-158 T 12-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 MIM_c21900 59ebbf95e240b4608ed6bc0dbe6d2fa0 585 Gene3D G3DSA:1.10.274.10 36 161 3.3E-66 T 12-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 MIM_c21900 59ebbf95e240b4608ed6bc0dbe6d2fa0 585 SUPERFAMILY SSF51621 272 565 1.84E-97 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MIM_c21900 59ebbf95e240b4608ed6bc0dbe6d2fa0 585 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 276 559 1.0E-105 T 12-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 MIM_c21900 59ebbf95e240b4608ed6bc0dbe6d2fa0 585 Pfam PF00391 PEP-utilising enzyme, mobile domain 176 245 5.4E-22 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MIM_c21900 59ebbf95e240b4608ed6bc0dbe6d2fa0 585 Pfam PF05524 PEP-utilising enzyme, N-terminal 18 141 7.6E-25 T 12-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 MIM_c21900 59ebbf95e240b4608ed6bc0dbe6d2fa0 585 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 466 484 - T 12-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 MIM_c21900 59ebbf95e240b4608ed6bc0dbe6d2fa0 585 PIRSF PIRSF000732 12 583 5.1E-200 T 12-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 MIM_c21900 59ebbf95e240b4608ed6bc0dbe6d2fa0 585 SUPERFAMILY SSF52009 140 266 9.16E-32 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 MIM_c21900 59ebbf95e240b4608ed6bc0dbe6d2fa0 585 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 519 531 1.1E-25 T 12-10-2018 MIM_c21900 59ebbf95e240b4608ed6bc0dbe6d2fa0 585 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 483 498 1.1E-25 T 12-10-2018 MIM_c21900 59ebbf95e240b4608ed6bc0dbe6d2fa0 585 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 466 481 1.1E-25 T 12-10-2018 MIM_c21900 59ebbf95e240b4608ed6bc0dbe6d2fa0 585 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 313 332 1.1E-25 T 12-10-2018 MIM_c21900 59ebbf95e240b4608ed6bc0dbe6d2fa0 585 Gene3D G3DSA:3.20.20.60 254 583 3.4E-110 T 12-10-2018 MIM_c21900 59ebbf95e240b4608ed6bc0dbe6d2fa0 585 SUPERFAMILY SSF47831 39 158 1.7E-28 T 12-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 MIM_c21900 59ebbf95e240b4608ed6bc0dbe6d2fa0 585 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 204 215 - T 12-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 MIM_c24810 0b5e9e7ba21817d381fdc54047c36fa6 326 Gene3D G3DSA:3.40.190.150 30 316 2.0E-115 T 12-10-2018 MIM_c24810 0b5e9e7ba21817d381fdc54047c36fa6 326 Gene3D G3DSA:3.40.190.10 128 251 2.0E-115 T 12-10-2018 MIM_c24810 0b5e9e7ba21817d381fdc54047c36fa6 326 PIRSF PIRSF017082 1 325 2.1E-81 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c24810 0b5e9e7ba21817d381fdc54047c36fa6 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 321 1.1E-87 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c24810 0b5e9e7ba21817d381fdc54047c36fa6 326 SUPERFAMILY SSF53850 113 290 3.39E-14 T 12-10-2018 MIM_c15080 6479826157b342b89a02fda583112891 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 179 198 1.1E-62 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MIM_c15080 6479826157b342b89a02fda583112891 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 311 337 1.1E-62 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MIM_c15080 6479826157b342b89a02fda583112891 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 49 70 1.1E-62 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MIM_c15080 6479826157b342b89a02fda583112891 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 33 49 1.1E-62 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MIM_c15080 6479826157b342b89a02fda583112891 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 76 90 1.1E-62 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MIM_c15080 6479826157b342b89a02fda583112891 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 125 141 1.1E-62 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MIM_c15080 6479826157b342b89a02fda583112891 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 266 285 1.1E-62 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MIM_c15080 6479826157b342b89a02fda583112891 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 92 105 1.1E-62 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MIM_c15080 6479826157b342b89a02fda583112891 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 156 170 1.1E-62 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MIM_c15080 6479826157b342b89a02fda583112891 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 216 235 1.1E-62 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MIM_c15080 6479826157b342b89a02fda583112891 367 Pfam PF13416 Bacterial extracellular solute-binding protein 47 332 2.4E-33 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein MIM_c15080 6479826157b342b89a02fda583112891 367 PIRSF PIRSF019574 1 367 3.6E-137 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MIM_c15080 6479826157b342b89a02fda583112891 367 SUPERFAMILY SSF53850 27 366 8.98E-96 T 12-10-2018 MIM_c15080 6479826157b342b89a02fda583112891 367 Gene3D G3DSA:3.40.190.10 30 335 2.3E-127 T 12-10-2018 MIM_c15080 6479826157b342b89a02fda583112891 367 Gene3D G3DSA:3.40.190.10 134 360 2.3E-127 T 12-10-2018 MIM_c11400 f7e7925ed7937281df7480927ec92228 356 Gene3D G3DSA:1.10.287.90 24 109 3.0E-30 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c11400 f7e7925ed7937281df7480927ec92228 356 SUPERFAMILY SSF49503 127 286 3.65E-49 T 12-10-2018 IPR008972 Cupredoxin MIM_c11400 f7e7925ed7937281df7480927ec92228 356 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 155 225 6.1E-7 T 12-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c11400 f7e7925ed7937281df7480927ec92228 356 TIGRFAM TIGR01433 CyoA: ubiquinol oxidase, subunit II 11 244 2.3E-108 T 12-10-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 MIM_c11400 f7e7925ed7937281df7480927ec92228 356 SUPERFAMILY SSF81464 26 114 2.62E-22 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c11400 f7e7925ed7937281df7480927ec92228 356 Gene3D G3DSA:2.60.40.420 110 286 3.8E-52 T 12-10-2018 IPR008972 Cupredoxin MIM_c11400 f7e7925ed7937281df7480927ec92228 356 PIRSF PIRSF000292 1 315 1.1E-127 T 12-10-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 MIM_c11400 f7e7925ed7937281df7480927ec92228 356 Pfam PF06481 COX Aromatic Rich Motif 244 289 8.1E-19 T 12-10-2018 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 MIM_c22530 c65e5f4ce217f8703a2a3bf1735ff7c7 89 Pfam PF11720 Peptidase inhibitor I78 family 30 89 3.5E-16 T 12-10-2018 IPR021719 Proteinase inhibitor I78 MIM_c22530 c65e5f4ce217f8703a2a3bf1735ff7c7 89 Gene3D G3DSA:3.30.10.10 26 88 2.3E-18 T 12-10-2018 MIM_c11830 57eaab5d5ce8890147cbe5e2a3507b0f 452 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 442 9.8E-152 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MIM_c11830 57eaab5d5ce8890147cbe5e2a3507b0f 452 PRINTS PR00981 Seryl-tRNA synthetase signature 359 375 1.1E-31 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MIM_c11830 57eaab5d5ce8890147cbe5e2a3507b0f 452 PRINTS PR00981 Seryl-tRNA synthetase signature 342 355 1.1E-31 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MIM_c11830 57eaab5d5ce8890147cbe5e2a3507b0f 452 PRINTS PR00981 Seryl-tRNA synthetase signature 377 393 1.1E-31 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MIM_c11830 57eaab5d5ce8890147cbe5e2a3507b0f 452 PRINTS PR00981 Seryl-tRNA synthetase signature 290 302 1.1E-31 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MIM_c11830 57eaab5d5ce8890147cbe5e2a3507b0f 452 PRINTS PR00981 Seryl-tRNA synthetase signature 302 315 1.1E-31 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MIM_c11830 57eaab5d5ce8890147cbe5e2a3507b0f 452 SUPERFAMILY SSF55681 136 445 2.74E-97 T 12-10-2018 MIM_c11830 57eaab5d5ce8890147cbe5e2a3507b0f 452 SUPERFAMILY SSF46589 1 112 2.04E-28 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 MIM_c11830 57eaab5d5ce8890147cbe5e2a3507b0f 452 Gene3D G3DSA:3.30.930.10 105 450 2.0E-112 T 12-10-2018 MIM_c11830 57eaab5d5ce8890147cbe5e2a3507b0f 452 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 447 38.503 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MIM_c11830 57eaab5d5ce8890147cbe5e2a3507b0f 452 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 5.1E-25 T 12-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 MIM_c11830 57eaab5d5ce8890147cbe5e2a3507b0f 452 PIRSF PIRSF001529 1 451 1.0E-161 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MIM_c11830 57eaab5d5ce8890147cbe5e2a3507b0f 452 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 249 425 5.1E-33 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c11830 57eaab5d5ce8890147cbe5e2a3507b0f 452 Gene3D G3DSA:1.10.287.40 1 104 8.9E-20 T 12-10-2018 MIM_c02070 8dde3fbac814793321b222db57d89ed4 230 Pfam PF00440 Bacterial regulatory proteins, tetR family 35 81 6.2E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c02070 8dde3fbac814793321b222db57d89ed4 230 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 48 1.1E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c02070 8dde3fbac814793321b222db57d89ed4 230 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 56 79 1.1E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c02070 8dde3fbac814793321b222db57d89ed4 230 SUPERFAMILY SSF46689 24 99 1.44E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c02070 8dde3fbac814793321b222db57d89ed4 230 SUPERFAMILY SSF48498 105 229 8.89E-27 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MIM_c02070 8dde3fbac814793321b222db57d89ed4 230 Gene3D G3DSA:1.10.357.10 33 230 2.9E-60 T 12-10-2018 MIM_c11080 99a9f325c3059a23c72402b9c8e716f5 238 SUPERFAMILY SSF89562 14 191 1.83E-41 T 12-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily MIM_c11080 99a9f325c3059a23c72402b9c8e716f5 238 Pfam PF03737 Aldolase/RraA 16 181 4.2E-32 T 12-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MIM_c11080 99a9f325c3059a23c72402b9c8e716f5 238 Gene3D G3DSA:3.50.30.100 2 203 1.0E-49 T 12-10-2018 MIM_c18290 b02ba78e306010a4633a1209c09c5edf 293 SUPERFAMILY SSF52210 128 291 4.84E-51 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c18290 b02ba78e306010a4633a1209c09c5edf 293 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 293 9.4E-128 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MIM_c18290 b02ba78e306010a4633a1209c09c5edf 293 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 241 254 - T 12-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site MIM_c18290 b02ba78e306010a4633a1209c09c5edf 293 Gene3D G3DSA:3.40.50.261 129 293 4.0E-67 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c18290 b02ba78e306010a4633a1209c09c5edf 293 Gene3D G3DSA:3.40.50.720 2 128 2.3E-42 T 12-10-2018 MIM_c18290 b02ba78e306010a4633a1209c09c5edf 293 Pfam PF02629 CoA binding domain 6 102 1.9E-22 T 12-10-2018 IPR003781 CoA-binding GO:0048037 MIM_c18290 b02ba78e306010a4633a1209c09c5edf 293 SUPERFAMILY SSF51735 1 127 1.47E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c18290 b02ba78e306010a4633a1209c09c5edf 293 PIRSF PIRSF001553 1 293 2.1E-117 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MIM_c18290 b02ba78e306010a4633a1209c09c5edf 293 SMART SM00881 4 103 3.6E-29 T 12-10-2018 IPR003781 CoA-binding GO:0048037 MIM_c18290 b02ba78e306010a4633a1209c09c5edf 293 PRINTS PR01798 Succinyl-CoA synthase signature 213 226 1.7E-34 T 12-10-2018 MIM_c18290 b02ba78e306010a4633a1209c09c5edf 293 PRINTS PR01798 Succinyl-CoA synthase signature 245 262 1.7E-34 T 12-10-2018 MIM_c18290 b02ba78e306010a4633a1209c09c5edf 293 PRINTS PR01798 Succinyl-CoA synthase signature 182 200 1.7E-34 T 12-10-2018 MIM_c18290 b02ba78e306010a4633a1209c09c5edf 293 PRINTS PR01798 Succinyl-CoA synthase signature 85 102 1.7E-34 T 12-10-2018 MIM_c18290 b02ba78e306010a4633a1209c09c5edf 293 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 293 40.464 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MIM_c18290 b02ba78e306010a4633a1209c09c5edf 293 Pfam PF00549 CoA-ligase 156 270 9.8E-16 T 12-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c18290 b02ba78e306010a4633a1209c09c5edf 293 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 157 186 - T 12-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site MIM_c13130 d1afa2d132b98f1319790c510186e1f0 396 SUPERFAMILY SSF53383 6 394 3.84E-98 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c13130 d1afa2d132b98f1319790c510186e1f0 396 Gene3D G3DSA:3.40.640.10 67 286 1.3E-132 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c13130 d1afa2d132b98f1319790c510186e1f0 396 Gene3D G3DSA:3.90.1150.10 20 393 1.3E-132 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c13130 d1afa2d132b98f1319790c510186e1f0 396 Pfam PF00155 Aminotransferase class I and II 52 386 7.6E-32 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MIM_c31350 7a7ae58ca0c5e0a07dd462f6c7339120 384 Pfam PF00285 Citrate synthase, C-terminal domain 18 367 3.1E-112 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 MIM_c31350 7a7ae58ca0c5e0a07dd462f6c7339120 384 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 17 384 1.5E-154 T 12-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 MIM_c31350 7a7ae58ca0c5e0a07dd462f6c7339120 384 PRINTS PR00143 Citrate synthase signature 337 351 1.2E-35 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 MIM_c31350 7a7ae58ca0c5e0a07dd462f6c7339120 384 PRINTS PR00143 Citrate synthase signature 260 280 1.2E-35 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 MIM_c31350 7a7ae58ca0c5e0a07dd462f6c7339120 384 PRINTS PR00143 Citrate synthase signature 135 148 1.2E-35 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 MIM_c31350 7a7ae58ca0c5e0a07dd462f6c7339120 384 PRINTS PR00143 Citrate synthase signature 317 333 1.2E-35 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 MIM_c31350 7a7ae58ca0c5e0a07dd462f6c7339120 384 PRINTS PR00143 Citrate synthase signature 207 235 1.2E-35 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 MIM_c31350 7a7ae58ca0c5e0a07dd462f6c7339120 384 PRINTS PR00143 Citrate synthase signature 185 200 1.2E-35 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 MIM_c31350 7a7ae58ca0c5e0a07dd462f6c7339120 384 PIRSF PIRSF001369 11 384 9.9E-108 T 12-10-2018 IPR024176 Citrate synthase, bacterial-type MIM_c31350 7a7ae58ca0c5e0a07dd462f6c7339120 384 SUPERFAMILY SSF48256 18 378 9.29E-123 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 MIM_c31350 7a7ae58ca0c5e0a07dd462f6c7339120 384 ProSitePatterns PS00480 Citrate synthase signature. 267 279 - T 12-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MIM_c31350 7a7ae58ca0c5e0a07dd462f6c7339120 384 Gene3D G3DSA:1.10.580.10 38 364 1.8E-124 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MIM_c31350 7a7ae58ca0c5e0a07dd462f6c7339120 384 Gene3D G3DSA:1.10.230.10 233 331 1.8E-124 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain MIM_c30390 9a1acfaa5988ee557d2aac79b6fe25b1 364 SUPERFAMILY SSF46689 285 336 1.48E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c30390 9a1acfaa5988ee557d2aac79b6fe25b1 364 SUPERFAMILY SSF52317 17 213 1.32E-35 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c30390 9a1acfaa5988ee557d2aac79b6fe25b1 364 Gene3D G3DSA:1.10.10.60 234 337 2.6E-29 T 12-10-2018 MIM_c30390 9a1acfaa5988ee557d2aac79b6fe25b1 364 SUPERFAMILY SSF46689 233 282 4.03E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c30390 9a1acfaa5988ee557d2aac79b6fe25b1 364 SMART SM00342 249 332 4.2E-29 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c30390 9a1acfaa5988ee557d2aac79b6fe25b1 364 Pfam PF12833 Helix-turn-helix domain 255 334 1.7E-23 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c30390 9a1acfaa5988ee557d2aac79b6fe25b1 364 Gene3D G3DSA:3.40.50.880 7 231 1.2E-41 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c30390 9a1acfaa5988ee557d2aac79b6fe25b1 364 Pfam PF01965 DJ-1/PfpI family 55 194 1.4E-9 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 MIM_c31480 f70b39eacd0c08f6ef90c35a32d8d380 161 Pfam PF01037 Lrp/AsnC ligand binding domain 72 144 2.3E-15 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MIM_c31480 f70b39eacd0c08f6ef90c35a32d8d380 161 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 52 4.9E-14 T 12-10-2018 MIM_c31480 f70b39eacd0c08f6ef90c35a32d8d380 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 6.5E-11 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MIM_c31480 f70b39eacd0c08f6ef90c35a32d8d380 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 6.5E-11 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MIM_c31480 f70b39eacd0c08f6ef90c35a32d8d380 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 6.5E-11 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MIM_c31480 f70b39eacd0c08f6ef90c35a32d8d380 161 Gene3D G3DSA:1.10.10.10 1 56 5.7E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c31480 f70b39eacd0c08f6ef90c35a32d8d380 161 SUPERFAMILY SSF54909 65 153 6.03E-14 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel MIM_c31480 f70b39eacd0c08f6ef90c35a32d8d380 161 Gene3D G3DSA:3.30.70.920 57 150 1.0E-18 T 12-10-2018 MIM_c31480 f70b39eacd0c08f6ef90c35a32d8d380 161 SUPERFAMILY SSF46785 4 65 3.62E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c31480 f70b39eacd0c08f6ef90c35a32d8d380 161 SMART SM00344 5 114 4.9E-34 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MIM_c13680 1839afd887b9fb5ed5e27a1b4c15bbb0 297 SUPERFAMILY SSF46785 6 90 2.1E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c13680 1839afd887b9fb5ed5e27a1b4c15bbb0 297 Gene3D G3DSA:1.10.10.10 5 93 5.4E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c13680 1839afd887b9fb5ed5e27a1b4c15bbb0 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 4.4E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c13680 1839afd887b9fb5ed5e27a1b4c15bbb0 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 4.4E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c13680 1839afd887b9fb5ed5e27a1b4c15bbb0 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 4.4E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c13680 1839afd887b9fb5ed5e27a1b4c15bbb0 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 1.8E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c13680 1839afd887b9fb5ed5e27a1b4c15bbb0 297 Pfam PF03466 LysR substrate binding domain 91 294 9.3E-35 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c13680 1839afd887b9fb5ed5e27a1b4c15bbb0 297 SUPERFAMILY SSF53850 91 295 3.26E-39 T 12-10-2018 MIM_c13680 1839afd887b9fb5ed5e27a1b4c15bbb0 297 Gene3D G3DSA:3.40.190.290 94 296 2.4E-50 T 12-10-2018 MIM_c04140 1598de2369db6af11249cf0b4fd64a7f 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.1E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c04140 1598de2369db6af11249cf0b4fd64a7f 308 Gene3D G3DSA:3.40.190.10 165 268 4.3E-49 T 12-10-2018 MIM_c04140 1598de2369db6af11249cf0b4fd64a7f 308 Gene3D G3DSA:1.10.10.10 3 90 7.1E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c04140 1598de2369db6af11249cf0b4fd64a7f 308 SUPERFAMILY SSF53850 90 295 6.15E-39 T 12-10-2018 MIM_c04140 1598de2369db6af11249cf0b4fd64a7f 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 3.7E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c04140 1598de2369db6af11249cf0b4fd64a7f 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 3.7E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c04140 1598de2369db6af11249cf0b4fd64a7f 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 3.7E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c04140 1598de2369db6af11249cf0b4fd64a7f 308 SUPERFAMILY SSF46785 4 89 7.82E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c04140 1598de2369db6af11249cf0b4fd64a7f 308 Gene3D G3DSA:3.40.190.10 93 292 4.3E-49 T 12-10-2018 MIM_c04140 1598de2369db6af11249cf0b4fd64a7f 308 Pfam PF03466 LysR substrate binding domain 89 293 3.0E-33 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c20630 6f3123534cdbbc41d43ed6d45f546baa 329 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 140 161 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 MIM_c20630 6f3123534cdbbc41d43ed6d45f546baa 329 SUPERFAMILY SSF51735 112 273 7.51E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c20630 6f3123534cdbbc41d43ed6d45f546baa 329 SMART SM00829 12 326 1.5E-40 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MIM_c20630 6f3123534cdbbc41d43ed6d45f546baa 329 Gene3D G3DSA:3.40.50.720 123 271 4.1E-91 T 12-10-2018 MIM_c20630 6f3123534cdbbc41d43ed6d45f546baa 329 Pfam PF00107 Zinc-binding dehydrogenase 151 278 1.6E-23 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MIM_c20630 6f3123534cdbbc41d43ed6d45f546baa 329 Gene3D G3DSA:3.90.180.10 12 322 4.1E-91 T 12-10-2018 MIM_c20630 6f3123534cdbbc41d43ed6d45f546baa 329 SUPERFAMILY SSF50129 1 139 1.67E-39 T 12-10-2018 IPR011032 GroES-like superfamily MIM_c20630 6f3123534cdbbc41d43ed6d45f546baa 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 91 1.7E-11 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MIM_c29750 9a8c5161625d5f7a86a5b56e620ab848 208 Pfam PF00578 AhpC/TSA family 52 164 2.0E-6 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MIM_c29750 9a8c5161625d5f7a86a5b56e620ab848 208 SUPERFAMILY SSF52833 48 182 4.82E-16 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c29750 9a8c5161625d5f7a86a5b56e620ab848 208 Gene3D G3DSA:3.40.30.10 46 182 1.2E-15 T 12-10-2018 MIM_c29750 9a8c5161625d5f7a86a5b56e620ab848 208 TIGRFAM TIGR02661 MauD: methylamine dehydrogenase accessory protein MauD 5 193 1.3E-98 T 12-10-2018 IPR013478 Methylamine dehydrogenase accessory protein MauD GO:0030416 MIM_c39810 c44ba0fee7e156866b1f4839dc80e4bf 234 SUPERFAMILY SSF100950 76 232 3.35E-28 T 12-10-2018 IPR037171 NagB/RpiA transferase-like MIM_c39810 c44ba0fee7e156866b1f4839dc80e4bf 234 Pfam PF00455 DeoR C terminal sensor domain 76 232 9.8E-48 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain MIM_c39810 c44ba0fee7e156866b1f4839dc80e4bf 234 Pfam PF08220 DeoR-like helix-turn-helix domain 6 41 2.8E-10 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MIM_c39810 c44ba0fee7e156866b1f4839dc80e4bf 234 SMART SM00420 6 55 9.6E-5 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MIM_c39810 c44ba0fee7e156866b1f4839dc80e4bf 234 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 MIM_c39810 c44ba0fee7e156866b1f4839dc80e4bf 234 SMART SM01134 73 234 4.2E-62 T 12-10-2018 MIM_c11700 b109d7c138fb098b570d41af87c65b1d 331 Gene3D G3DSA:3.40.190.150 32 321 2.0E-91 T 12-10-2018 MIM_c11700 b109d7c138fb098b570d41af87c65b1d 331 SUPERFAMILY SSF53850 118 289 4.19E-8 T 12-10-2018 MIM_c11700 b109d7c138fb098b570d41af87c65b1d 331 PIRSF PIRSF017082 4 330 6.7E-70 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c11700 b109d7c138fb098b570d41af87c65b1d 331 Gene3D G3DSA:3.40.190.10 128 253 2.0E-91 T 12-10-2018 MIM_c11700 b109d7c138fb098b570d41af87c65b1d 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 328 9.1E-67 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c14540 2d40bd6fe7e055379cdef37b10aff235 290 Gene3D G3DSA:3.30.1600.10 34 194 8.6E-77 T 12-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily MIM_c14540 2d40bd6fe7e055379cdef37b10aff235 290 SUPERFAMILY SSF52467 4 269 9.0E-74 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MIM_c14540 2d40bd6fe7e055379cdef37b10aff235 290 Gene3D G3DSA:3.40.50.1220 12 266 8.6E-77 T 12-10-2018 MIM_c14540 2d40bd6fe7e055379cdef37b10aff235 290 Pfam PF02146 Sir2 family 24 225 1.7E-45 T 12-10-2018 IPR003000 Sirtuin family GO:0070403 MIM_c14540 2d40bd6fe7e055379cdef37b10aff235 290 Hamap MF_01967 NAD-dependent protein deacetylase [cobB]. 1 269 58.969 T 12-10-2018 IPR026587 Sirtuin, class II Reactome: R-HSA-2151201 MIM_c16450 d73aefbfb21c25ae299cb2799adebb92 609 SMART SM00465 17 98 4.3E-17 T 12-10-2018 IPR000305 GIY-YIG endonuclease MIM_c16450 d73aefbfb21c25ae299cb2799adebb92 609 Gene3D G3DSA:1.10.150.20 555 609 3.6E-21 T 12-10-2018 MIM_c16450 d73aefbfb21c25ae299cb2799adebb92 609 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 7 588 1.1E-175 T 12-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 MIM_c16450 d73aefbfb21c25ae299cb2799adebb92 609 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 396 542 4.1E-43 T 12-10-2018 IPR001162 UvrC family homology region MIM_c16450 d73aefbfb21c25ae299cb2799adebb92 609 Gene3D G3DSA:3.40.1440.10 4 102 7.7E-32 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 MIM_c16450 d73aefbfb21c25ae299cb2799adebb92 609 SUPERFAMILY SSF47781 524 609 3.81E-18 T 12-10-2018 IPR010994 RuvA domain 2-like MIM_c16450 d73aefbfb21c25ae299cb2799adebb92 609 Pfam PF01541 GIY-YIG catalytic domain 19 93 1.3E-8 T 12-10-2018 IPR000305 GIY-YIG endonuclease MIM_c16450 d73aefbfb21c25ae299cb2799adebb92 609 SUPERFAMILY SSF46600 190 242 6.28E-13 T 12-10-2018 IPR036876 UVR domain superfamily MIM_c16450 d73aefbfb21c25ae299cb2799adebb92 609 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 607 27.155 T 12-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 MIM_c16450 d73aefbfb21c25ae299cb2799adebb92 609 Pfam PF02151 UvrB/uvrC motif 204 234 3.0E-8 T 12-10-2018 IPR001943 UVR domain GO:0005515 MIM_c16450 d73aefbfb21c25ae299cb2799adebb92 609 Gene3D G3DSA:3.30.420.340 379 542 6.3E-44 T 12-10-2018 IPR038476 UvrC homology region 2 superfamily MIM_c16450 d73aefbfb21c25ae299cb2799adebb92 609 SUPERFAMILY SSF82771 17 100 4.32E-22 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 MIM_c16450 d73aefbfb21c25ae299cb2799adebb92 609 Pfam PF14520 Helix-hairpin-helix domain 557 609 2.0E-8 T 12-10-2018 MIM_c16450 d73aefbfb21c25ae299cb2799adebb92 609 SMART SM00278 556 575 1.6 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MIM_c16450 d73aefbfb21c25ae299cb2799adebb92 609 SMART SM00278 588 607 0.41 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MIM_c24540 4ab97ce8f0fad447803b122dfd39527f 453 SMART SM00928 356 401 7.3E-24 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24540 4ab97ce8f0fad447803b122dfd39527f 453 Pfam PF10531 SLBB domain 270 318 4.7E-14 T 12-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24540 4ab97ce8f0fad447803b122dfd39527f 453 SUPERFAMILY SSF140490 353 450 4.97E-37 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24540 4ab97ce8f0fad447803b122dfd39527f 453 SUPERFAMILY SSF142984 268 351 8.5E-26 T 12-10-2018 MIM_c24540 4ab97ce8f0fad447803b122dfd39527f 453 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 75 246 3.0E-47 T 12-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24540 4ab97ce8f0fad447803b122dfd39527f 453 Gene3D G3DSA:3.40.50.11540 80 257 2.3E-76 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24540 4ab97ce8f0fad447803b122dfd39527f 453 Gene3D G3DSA:3.10.20.600 259 353 3.0E-34 T 12-10-2018 MIM_c24540 4ab97ce8f0fad447803b122dfd39527f 453 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 360 441 1.0E-29 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24540 4ab97ce8f0fad447803b122dfd39527f 453 SUPERFAMILY SSF142019 41 267 2.35E-85 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24540 4ab97ce8f0fad447803b122dfd39527f 453 Gene3D G3DSA:1.20.1440.230 354 452 1.4E-32 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24540 4ab97ce8f0fad447803b122dfd39527f 453 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 369 380 - T 12-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24540 4ab97ce8f0fad447803b122dfd39527f 453 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 41 442 3.3E-193 T 12-10-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c22730 f6c30e1a8560cff7353e31e8b7401668 187 SUPERFAMILY SSF47781 14 72 2.56E-13 T 12-10-2018 IPR010994 RuvA domain 2-like MIM_c22730 f6c30e1a8560cff7353e31e8b7401668 187 Gene3D G3DSA:1.10.150.280 7 77 1.2E-13 T 12-10-2018 MIM_c22730 f6c30e1a8560cff7353e31e8b7401668 187 SMART SM00278 23 42 0.42 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MIM_c22730 f6c30e1a8560cff7353e31e8b7401668 187 SMART SM00278 53 72 110.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MIM_c22730 f6c30e1a8560cff7353e31e8b7401668 187 Pfam PF12836 Helix-hairpin-helix motif 12 69 4.7E-14 T 12-10-2018 MIM_c38410 bd1e71cadf10bcbc84aee2bd043f3956 324 SUPERFAMILY SSF53850 115 288 1.81E-9 T 12-10-2018 MIM_c38410 bd1e71cadf10bcbc84aee2bd043f3956 324 Gene3D G3DSA:3.40.190.150 31 314 1.2E-84 T 12-10-2018 MIM_c38410 bd1e71cadf10bcbc84aee2bd043f3956 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 320 3.0E-57 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c38410 bd1e71cadf10bcbc84aee2bd043f3956 324 PIRSF PIRSF017082 1 324 2.0E-61 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c38410 bd1e71cadf10bcbc84aee2bd043f3956 324 Gene3D G3DSA:3.40.190.10 126 249 1.2E-84 T 12-10-2018 MIM_c29040 fb20ed7aaee26b7efa91b333e3e426ce 411 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 266 381 8.1E-30 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MIM_c29040 fb20ed7aaee26b7efa91b333e3e426ce 411 Gene3D G3DSA:3.40.50.300 11 239 1.9E-71 T 12-10-2018 MIM_c29040 fb20ed7aaee26b7efa91b333e3e426ce 411 SMART SM00833 266 381 1.6E-54 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MIM_c29040 fb20ed7aaee26b7efa91b333e3e426ce 411 SUPERFAMILY SSF52540 9 315 9.56E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c29040 fb20ed7aaee26b7efa91b333e3e426ce 411 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 15 219 9.2E-58 T 12-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain MIM_c38020 dc8d548baa7c6ec2c38d99ea4a28ea24 216 Pfam PF12059 Protein of unknown function (DUF3540) 21 216 5.6E-72 T 12-10-2018 IPR021927 Protein of unknown function DUF3540 MIM_c14120 47869f72f91193db747b44ebd25973b5 1000 SUPERFAMILY SSF52540 499 671 2.09E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c14120 47869f72f91193db747b44ebd25973b5 1000 Pfam PF00009 Elongation factor Tu GTP binding domain 506 661 2.6E-36 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c14120 47869f72f91193db747b44ebd25973b5 1000 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 418 1000 8.4E-254 T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 MIM_c14120 47869f72f91193db747b44ebd25973b5 1000 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 505 660 7.7E-35 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MIM_c14120 47869f72f91193db747b44ebd25973b5 1000 Gene3D G3DSA:2.40.30.10 673 791 2.6E-38 T 12-10-2018 MIM_c14120 47869f72f91193db747b44ebd25973b5 1000 Pfam PF11987 Translation-initiation factor 2 786 889 8.1E-36 T 12-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 MIM_c14120 47869f72f91193db747b44ebd25973b5 1000 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 998 17.359 T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 MIM_c14120 47869f72f91193db747b44ebd25973b5 1000 SUPERFAMILY SSF50447 902 998 2.21E-31 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MIM_c14120 47869f72f91193db747b44ebd25973b5 1000 ProSitePatterns PS01176 Initiation factor 2 signature. 951 973 - T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 MIM_c14120 47869f72f91193db747b44ebd25973b5 1000 Gene3D G3DSA:3.40.50.300 498 672 7.9E-73 T 12-10-2018 MIM_c14120 47869f72f91193db747b44ebd25973b5 1000 Gene3D G3DSA:2.40.30.10 902 999 5.1E-30 T 12-10-2018 MIM_c14120 47869f72f91193db747b44ebd25973b5 1000 Gene3D G3DSA:3.30.56.50 3 51 1.5E-5 T 12-10-2018 MIM_c14120 47869f72f91193db747b44ebd25973b5 1000 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 60 97 4.2E-13 T 12-10-2018 IPR013575 Initiation factor 2 associated domain, bacterial MIM_c14120 47869f72f91193db747b44ebd25973b5 1000 SUPERFAMILY SSF46955 4 51 3.84E-9 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily MIM_c14120 47869f72f91193db747b44ebd25973b5 1000 SUPERFAMILY SSF50447 674 755 6.41E-25 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MIM_c14120 47869f72f91193db747b44ebd25973b5 1000 SUPERFAMILY SSF52156 779 907 1.14E-36 T 12-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily MIM_c14120 47869f72f91193db747b44ebd25973b5 1000 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 3 50 2.4E-7 T 12-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal MIM_c14120 47869f72f91193db747b44ebd25973b5 1000 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 424 474 2.4E-15 T 12-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal MIM_c14120 47869f72f91193db747b44ebd25973b5 1000 Gene3D G3DSA:3.40.50.10050 794 901 1.2E-37 T 12-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily MIM_c13750 5d44d5092fb9cac322f568c3365050ee 283 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 39 56 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MIM_c13750 5d44d5092fb9cac322f568c3365050ee 283 SUPERFAMILY SSF51430 3 262 9.3E-87 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MIM_c13750 5d44d5092fb9cac322f568c3365050ee 283 PIRSF PIRSF000097 1 115 1.4E-37 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MIM_c13750 5d44d5092fb9cac322f568c3365050ee 283 PIRSF PIRSF000097 110 271 2.7E-42 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MIM_c13750 5d44d5092fb9cac322f568c3365050ee 283 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 120 137 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MIM_c13750 5d44d5092fb9cac322f568c3365050ee 283 PRINTS PR00069 Aldo-keto reductase signature 154 183 3.2E-41 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MIM_c13750 5d44d5092fb9cac322f568c3365050ee 283 PRINTS PR00069 Aldo-keto reductase signature 193 217 3.2E-41 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MIM_c13750 5d44d5092fb9cac322f568c3365050ee 283 PRINTS PR00069 Aldo-keto reductase signature 120 137 3.2E-41 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MIM_c13750 5d44d5092fb9cac322f568c3365050ee 283 PRINTS PR00069 Aldo-keto reductase signature 35 59 3.2E-41 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MIM_c13750 5d44d5092fb9cac322f568c3365050ee 283 PRINTS PR00069 Aldo-keto reductase signature 91 109 3.2E-41 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MIM_c13750 5d44d5092fb9cac322f568c3365050ee 283 Pfam PF00248 Aldo/keto reductase family 16 256 4.6E-45 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain MIM_c13750 5d44d5092fb9cac322f568c3365050ee 283 Gene3D G3DSA:3.20.20.100 1 283 2.9E-123 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MIM_c25460 d6c47ffe935498c78e56b85ded5fe1cf 268 Gene3D G3DSA:2.60.120.10 124 267 4.6E-58 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c25460 d6c47ffe935498c78e56b85ded5fe1cf 268 Pfam PF04962 KduI/IolB family 8 265 2.8E-95 T 12-10-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 MIM_c25460 d6c47ffe935498c78e56b85ded5fe1cf 268 SUPERFAMILY SSF51182 12 254 2.71E-57 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c25460 d6c47ffe935498c78e56b85ded5fe1cf 268 PIRSF PIRSF036628 1 268 6.8E-97 T 12-10-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 MIM_c25460 d6c47ffe935498c78e56b85ded5fe1cf 268 TIGRFAM TIGR04378 myo_inos_iolB: 5-deoxy-glucuronate isomerase 20 265 1.8E-89 T 12-10-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 MIM_c25460 d6c47ffe935498c78e56b85ded5fe1cf 268 Gene3D G3DSA:2.60.120.10 11 123 3.1E-23 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c31680 b2acaedbc38dd86a5ca58957f67e90d0 294 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 248 290 1.1E-13 T 12-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain MIM_c31680 b2acaedbc38dd86a5ca58957f67e90d0 294 Gene3D G3DSA:3.40.50.80 132 241 1.2E-8 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MIM_c31680 b2acaedbc38dd86a5ca58957f67e90d0 294 Gene3D G3DSA:2.10.240.10 248 292 3.0E-12 T 12-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily MIM_c31680 b2acaedbc38dd86a5ca58957f67e90d0 294 SUPERFAMILY SSF52343 124 290 1.87E-21 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MIM_c31680 b2acaedbc38dd86a5ca58957f67e90d0 294 SUPERFAMILY SSF63380 32 129 2.15E-20 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MIM_c31680 b2acaedbc38dd86a5ca58957f67e90d0 294 Gene3D G3DSA:2.40.30.10 29 127 6.4E-25 T 12-10-2018 MIM_c31680 b2acaedbc38dd86a5ca58957f67e90d0 294 PIRSF PIRSF006816 28 294 1.0E-45 T 12-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 MIM_c28600 ae908cad73c6959fa24455c5c5e528a5 440 Pfam PF00512 His Kinase A (phospho-acceptor) domain 218 268 4.8E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MIM_c28600 ae908cad73c6959fa24455c5c5e528a5 440 Pfam PF00672 HAMP domain 165 210 2.1E-6 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MIM_c28600 ae908cad73c6959fa24455c5c5e528a5 440 SUPERFAMILY SSF47384 199 271 6.47E-12 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MIM_c28600 ae908cad73c6959fa24455c5c5e528a5 440 SMART SM00388 216 279 0.002 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MIM_c28600 ae908cad73c6959fa24455c5c5e528a5 440 Gene3D G3DSA:1.20.1480.50 131 220 9.6E-10 T 12-10-2018 MIM_c28600 ae908cad73c6959fa24455c5c5e528a5 440 Gene3D G3DSA:1.10.287.130 221 279 2.3E-32 T 12-10-2018 MIM_c28600 ae908cad73c6959fa24455c5c5e528a5 440 SMART SM00304 165 215 2.0E-4 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MIM_c28600 ae908cad73c6959fa24455c5c5e528a5 440 SMART SM00387 323 440 1.9E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c28600 ae908cad73c6959fa24455c5c5e528a5 440 SUPERFAMILY SSF55874 282 433 6.42E-22 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c28600 ae908cad73c6959fa24455c5c5e528a5 440 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 329 433 3.8E-12 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c28600 ae908cad73c6959fa24455c5c5e528a5 440 SUPERFAMILY SSF158472 165 212 3.92E-6 T 12-10-2018 MIM_c28600 ae908cad73c6959fa24455c5c5e528a5 440 Gene3D G3DSA:3.30.565.10 280 433 2.3E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c26500 eacfaf5a42e1f25386806de31027dab9 276 Gene3D G3DSA:3.40.1080.10 12 260 3.1E-56 T 12-10-2018 MIM_c26500 eacfaf5a42e1f25386806de31027dab9 276 Gene3D G3DSA:3.30.30.40 123 159 3.1E-56 T 12-10-2018 MIM_c26500 eacfaf5a42e1f25386806de31027dab9 276 SUPERFAMILY SSF100950 9 255 4.84E-58 T 12-10-2018 IPR037171 NagB/RpiA transferase-like MIM_c26500 eacfaf5a42e1f25386806de31027dab9 276 Pfam PF01144 Coenzyme A transferase 13 227 7.1E-21 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MIM_c26500 eacfaf5a42e1f25386806de31027dab9 276 SMART SM00882 11 231 3.1E-24 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MIM_c25070 7f47df43522233de22234dd712295f22 161 Gene3D G3DSA:3.10.129.10 9 158 1.2E-40 T 12-10-2018 MIM_c25070 7f47df43522233de22234dd712295f22 161 Pfam PF01575 MaoC like domain 21 128 5.5E-10 T 12-10-2018 IPR002539 MaoC-like dehydratase domain MIM_c25070 7f47df43522233de22234dd712295f22 161 SUPERFAMILY SSF54637 9 155 1.95E-29 T 12-10-2018 IPR029069 HotDog domain superfamily MIM_c08970 fcc3f87a630c75a19afd3dd196b5baeb 707 Pfam PF00593 TonB dependent receptor 270 705 9.3E-32 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MIM_c08970 fcc3f87a630c75a19afd3dd196b5baeb 707 Pfam PF07715 TonB-dependent Receptor Plug Domain 71 172 1.2E-8 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain MIM_c08970 fcc3f87a630c75a19afd3dd196b5baeb 707 SUPERFAMILY SSF56935 67 707 3.43E-91 T 12-10-2018 MIM_c08970 fcc3f87a630c75a19afd3dd196b5baeb 707 Gene3D G3DSA:2.40.170.20 65 707 4.1E-109 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MIM_c04030 bfa871716c2d3d4d1efdbf8da24d5ce2 228 SUPERFAMILY SSF52540 21 200 4.19E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c04030 bfa871716c2d3d4d1efdbf8da24d5ce2 228 Pfam PF13476 AAA domain 22 59 6.8E-8 T 12-10-2018 IPR038729 Rad50/SbcC-type AAA domain MIM_c04030 bfa871716c2d3d4d1efdbf8da24d5ce2 228 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 130 183 5.3E-8 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MIM_c04030 bfa871716c2d3d4d1efdbf8da24d5ce2 228 SMART SM00382 18 195 7.0E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c04030 bfa871716c2d3d4d1efdbf8da24d5ce2 228 Gene3D G3DSA:3.40.50.300 6 72 1.5E-7 T 12-10-2018 MIM_c04030 bfa871716c2d3d4d1efdbf8da24d5ce2 228 Gene3D G3DSA:3.40.50.300 85 206 3.6E-11 T 12-10-2018 MIM_c24160 2c994f2f1fb3bc11e78f8b0e0d49170d 259 Pfam PF00175 Oxidoreductase NAD-binding domain 120 235 1.9E-10 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MIM_c24160 2c994f2f1fb3bc11e78f8b0e0d49170d 259 SUPERFAMILY SSF52343 112 249 1.22E-29 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MIM_c24160 2c994f2f1fb3bc11e78f8b0e0d49170d 259 Gene3D G3DSA:2.40.30.10 1 105 6.8E-26 T 12-10-2018 MIM_c24160 2c994f2f1fb3bc11e78f8b0e0d49170d 259 Gene3D G3DSA:3.40.50.80 106 259 1.3E-37 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MIM_c24160 2c994f2f1fb3bc11e78f8b0e0d49170d 259 SUPERFAMILY SSF63380 14 107 2.33E-18 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MIM_c24160 2c994f2f1fb3bc11e78f8b0e0d49170d 259 PRINTS PR00410 Phenol hydroxylase reductase family signature 119 138 5.4E-6 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MIM_c24160 2c994f2f1fb3bc11e78f8b0e0d49170d 259 PRINTS PR00410 Phenol hydroxylase reductase family signature 35 47 5.4E-6 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MIM_c24160 2c994f2f1fb3bc11e78f8b0e0d49170d 259 PRINTS PR00410 Phenol hydroxylase reductase family signature 220 228 5.4E-6 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MIM_c24160 2c994f2f1fb3bc11e78f8b0e0d49170d 259 PRINTS PR00410 Phenol hydroxylase reductase family signature 144 153 5.4E-6 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MIM_c12570 08603bba8a7fd19715b09ab5493710f5 188 SUPERFAMILY SSF48452 74 162 2.11E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MIM_c12570 08603bba8a7fd19715b09ab5493710f5 188 Gene3D G3DSA:1.25.40.10 7 177 3.1E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MIM_c12570 08603bba8a7fd19715b09ab5493710f5 188 SMART SM00028 77 110 150.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MIM_c12570 08603bba8a7fd19715b09ab5493710f5 188 SMART SM00028 111 144 0.0011 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MIM_c04110 cebc472ed32247e6a41508650f767f74 91 SUPERFAMILY SSF54909 16 89 8.94E-11 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel MIM_c04110 cebc472ed32247e6a41508650f767f74 91 Gene3D G3DSA:3.30.70.100 11 91 1.2E-9 T 12-10-2018 MIM_c04110 cebc472ed32247e6a41508650f767f74 91 Pfam PF03992 Antibiotic biosynthesis monooxygenase 18 68 5.8E-5 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain MIM_c05650 2d5414f4add1a4f37bed280fae474383 340 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 25 302 7.4E-82 T 12-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B MIM_c05650 2d5414f4add1a4f37bed280fae474383 340 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 3 327 2.3E-78 T 12-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B MIM_c05650 2d5414f4add1a4f37bed280fae474383 340 SMART SM00797 24 319 2.0E-103 T 12-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B MIM_c05650 2d5414f4add1a4f37bed280fae474383 340 Gene3D G3DSA:2.40.100.10 192 329 3.4E-47 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily MIM_c13930 8dd6843bf9844d1851c4d851b65c67d1 254 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c13930 8dd6843bf9844d1851c4d851b65c67d1 254 Gene3D G3DSA:3.40.50.300 1 250 9.3E-59 T 12-10-2018 MIM_c13930 8dd6843bf9844d1851c4d851b65c67d1 254 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 228 248 2.9E-6 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal MIM_c13930 8dd6843bf9844d1851c4d851b65c67d1 254 Pfam PF00005 ABC transporter 22 176 1.8E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c13930 8dd6843bf9844d1851c4d851b65c67d1 254 SUPERFAMILY SSF52540 4 250 8.49E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c13930 8dd6843bf9844d1851c4d851b65c67d1 254 SMART SM00382 30 225 2.4E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c03660 e4921deac4444e6a29449dbbf435bd7c 385 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 9 383 22.698 T 12-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 MIM_c03660 e4921deac4444e6a29449dbbf435bd7c 385 Gene3D G3DSA:1.20.1530.10 7 385 2.4E-142 T 12-10-2018 IPR023171 Na/H antiporter domain superfamily MIM_c03660 e4921deac4444e6a29449dbbf435bd7c 385 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 12 377 3.1E-133 T 12-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 MIM_c03660 e4921deac4444e6a29449dbbf435bd7c 385 Pfam PF06965 Na+/H+ antiporter 1 11 377 2.2E-141 T 12-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 MIM_c25650 69c9dca3e0208e31f7c730f2ad580bff 829 Pfam PF07660 Secretin and TonB N terminus short domain 70 118 1.6E-11 T 12-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MIM_c25650 69c9dca3e0208e31f7c730f2ad580bff 829 Gene3D G3DSA:3.55.50.30 45 118 6.1E-22 T 12-10-2018 MIM_c25650 69c9dca3e0208e31f7c730f2ad580bff 829 Gene3D G3DSA:2.170.130.10 150 284 5.9E-39 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MIM_c25650 69c9dca3e0208e31f7c730f2ad580bff 829 SUPERFAMILY SSF56935 129 829 3.92E-118 T 12-10-2018 MIM_c25650 69c9dca3e0208e31f7c730f2ad580bff 829 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 175 825 3.1E-97 T 12-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 MIM_c25650 69c9dca3e0208e31f7c730f2ad580bff 829 Pfam PF00593 TonB dependent receptor 362 827 8.4E-47 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MIM_c25650 69c9dca3e0208e31f7c730f2ad580bff 829 Gene3D G3DSA:2.40.170.20 285 829 6.5E-154 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MIM_c25650 69c9dca3e0208e31f7c730f2ad580bff 829 Pfam PF07715 TonB-dependent Receptor Plug Domain 173 277 1.0E-16 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain MIM_c25650 69c9dca3e0208e31f7c730f2ad580bff 829 SMART SM00965 70 120 7.4E-13 T 12-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MIM_c27550 4e7b67eb16222bfa1e205d2bf7fa2754 439 SUPERFAMILY SSF103473 17 425 5.36E-56 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c27550 4e7b67eb16222bfa1e205d2bf7fa2754 439 Pfam PF00083 Sugar (and other) transporter 238 417 2.3E-5 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MIM_c27550 4e7b67eb16222bfa1e205d2bf7fa2754 439 Pfam PF00083 Sugar (and other) transporter 20 221 2.5E-17 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MIM_c27550 4e7b67eb16222bfa1e205d2bf7fa2754 439 ProSitePatterns PS00217 Sugar transport proteins signature 2. 128 153 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MIM_c27550 4e7b67eb16222bfa1e205d2bf7fa2754 439 Gene3D G3DSA:1.20.1250.20 17 426 2.1E-49 T 12-10-2018 MIM_c24090 7e08517b9bb4702b842e49314bdc626a 276 Gene3D G3DSA:3.20.20.70 1 275 2.4E-90 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c24090 7e08517b9bb4702b842e49314bdc626a 276 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 16 246 1.0E-66 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MIM_c24090 7e08517b9bb4702b842e49314bdc626a 276 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 13 270 31.529 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MIM_c24090 7e08517b9bb4702b842e49314bdc626a 276 SUPERFAMILY SSF51366 5 246 3.48E-79 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MIM_c24090 7e08517b9bb4702b842e49314bdc626a 276 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 12-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MIM_c24090 7e08517b9bb4702b842e49314bdc626a 276 Pfam PF00290 Tryptophan synthase alpha chain 15 248 1.6E-79 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MIM_c23480 2e53456dafc5e00c70a7e986b5e6a924 406 Gene3D G3DSA:1.20.1720.10 16 395 5.0E-103 T 12-10-2018 MIM_c23480 2e53456dafc5e00c70a7e986b5e6a924 406 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 16 392 5.0E-93 T 12-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 MIM_c23480 2e53456dafc5e00c70a7e986b5e6a924 406 SUPERFAMILY SSF103473 11 397 4.97E-62 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c23480 2e53456dafc5e00c70a7e986b5e6a924 406 Pfam PF07690 Major Facilitator Superfamily 22 362 2.5E-39 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c13210 59dc4f82a93f868981487b0f6f64024d 329 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 5 322 2.8E-145 T 12-10-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 MIM_c13210 59dc4f82a93f868981487b0f6f64024d 329 PIRSF PIRSF000102 2 326 4.4E-66 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MIM_c13210 59dc4f82a93f868981487b0f6f64024d 329 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 6 155 1.7E-38 T 12-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c13210 59dc4f82a93f868981487b0f6f64024d 329 SUPERFAMILY SSF56327 160 328 1.08E-60 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 MIM_c13210 59dc4f82a93f868981487b0f6f64024d 329 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 160 322 5.8E-33 T 12-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 MIM_c13210 59dc4f82a93f868981487b0f6f64024d 329 Gene3D G3DSA:3.90.110.10 158 329 1.6E-62 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 MIM_c13210 59dc4f82a93f868981487b0f6f64024d 329 SUPERFAMILY SSF51735 5 158 1.39E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c13210 59dc4f82a93f868981487b0f6f64024d 329 Gene3D G3DSA:3.40.50.720 1 157 6.5E-61 T 12-10-2018 MIM_c13210 59dc4f82a93f868981487b0f6f64024d 329 Hamap MF_01517 Malate dehydrogenase [mdh]. 2 328 56.598 T 12-10-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 MIM_c05350 b08da0ab3e18f0f8321d10d4b9e9690c 343 Pfam PF02885 Glycosyl transferase family, helical bundle domain 7 68 2.2E-11 T 12-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 MIM_c05350 b08da0ab3e18f0f8321d10d4b9e9690c 343 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 10 335 3.2E-123 T 12-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 MIM_c05350 b08da0ab3e18f0f8321d10d4b9e9690c 343 Pfam PF00591 Glycosyl transferase family, a/b domain 78 327 6.3E-91 T 12-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MIM_c05350 b08da0ab3e18f0f8321d10d4b9e9690c 343 SUPERFAMILY SSF47648 4 71 3.14E-16 T 12-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MIM_c05350 b08da0ab3e18f0f8321d10d4b9e9690c 343 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 7 337 36.137 T 12-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 MIM_c05350 b08da0ab3e18f0f8321d10d4b9e9690c 343 Gene3D G3DSA:3.40.1030.10 74 342 1.1E-104 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MIM_c05350 b08da0ab3e18f0f8321d10d4b9e9690c 343 SUPERFAMILY SSF52418 77 340 1.44E-93 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MIM_c05350 b08da0ab3e18f0f8321d10d4b9e9690c 343 Gene3D G3DSA:1.20.970.10 1 72 9.1E-29 T 12-10-2018 MIM_c37440 ae17a2e8815496fa5d08d1719f4e7b9a 528 Gene3D G3DSA:3.40.250.10 263 353 3.9E-15 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily MIM_c37440 ae17a2e8815496fa5d08d1719f4e7b9a 528 SMART SM00450 5 104 3.9E-11 T 12-10-2018 IPR001763 Rhodanese-like domain MIM_c37440 ae17a2e8815496fa5d08d1719f4e7b9a 528 SMART SM00450 378 462 18.0 T 12-10-2018 IPR001763 Rhodanese-like domain MIM_c37440 ae17a2e8815496fa5d08d1719f4e7b9a 528 SMART SM00450 131 229 9.1E-10 T 12-10-2018 IPR001763 Rhodanese-like domain MIM_c37440 ae17a2e8815496fa5d08d1719f4e7b9a 528 SUPERFAMILY SSF52821 256 353 4.71E-14 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily MIM_c37440 ae17a2e8815496fa5d08d1719f4e7b9a 528 Gene3D G3DSA:3.40.250.10 126 233 7.0E-22 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily MIM_c37440 ae17a2e8815496fa5d08d1719f4e7b9a 528 Gene3D G3DSA:3.40.250.10 2 108 2.2E-18 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily MIM_c37440 ae17a2e8815496fa5d08d1719f4e7b9a 528 SUPERFAMILY SSF52821 106 235 6.29E-31 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily MIM_c37440 ae17a2e8815496fa5d08d1719f4e7b9a 528 Pfam PF00581 Rhodanese-like domain 7 101 5.6E-8 T 12-10-2018 IPR001763 Rhodanese-like domain MIM_c37440 ae17a2e8815496fa5d08d1719f4e7b9a 528 Pfam PF00581 Rhodanese-like domain 131 225 1.9E-10 T 12-10-2018 IPR001763 Rhodanese-like domain MIM_c37440 ae17a2e8815496fa5d08d1719f4e7b9a 528 SUPERFAMILY SSF52821 2 122 3.54E-22 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily MIM_c37440 ae17a2e8815496fa5d08d1719f4e7b9a 528 SUPERFAMILY SSF52821 364 457 1.57E-8 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily MIM_c37440 ae17a2e8815496fa5d08d1719f4e7b9a 528 Gene3D G3DSA:3.40.250.10 369 468 2.3E-5 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily MIM_c35030 188f87d307e5e425a497dbea97c8dc54 264 Pfam PF00005 ABC transporter 30 190 8.8E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c35030 188f87d307e5e425a497dbea97c8dc54 264 Gene3D G3DSA:3.40.50.300 13 262 5.4E-64 T 12-10-2018 MIM_c35030 188f87d307e5e425a497dbea97c8dc54 264 SUPERFAMILY SSF52540 15 259 1.17E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c35030 188f87d307e5e425a497dbea97c8dc54 264 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c35030 188f87d307e5e425a497dbea97c8dc54 264 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 240 261 1.4E-4 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal MIM_c35030 188f87d307e5e425a497dbea97c8dc54 264 SMART SM00382 39 238 2.9E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c29460 e780c25ebd18e14ac312567e41dc04ea 462 Pfam PF02875 Mur ligase family, glutamate ligase domain 313 378 3.6E-10 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 MIM_c29460 e780c25ebd18e14ac312567e41dc04ea 462 Gene3D G3DSA:3.40.1190.10 91 314 4.9E-56 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MIM_c29460 e780c25ebd18e14ac312567e41dc04ea 462 SUPERFAMILY SSF53623 97 309 2.22E-48 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MIM_c29460 e780c25ebd18e14ac312567e41dc04ea 462 Hamap MF_02020 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase [mpl]. 1 454 56.101 T 12-10-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 MetaCyc: PWY-7883 MIM_c29460 e780c25ebd18e14ac312567e41dc04ea 462 Pfam PF08245 Mur ligase middle domain 108 292 2.7E-21 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MIM_c29460 e780c25ebd18e14ac312567e41dc04ea 462 Gene3D G3DSA:3.40.50.720 1 90 3.1E-35 T 12-10-2018 MIM_c29460 e780c25ebd18e14ac312567e41dc04ea 462 Gene3D G3DSA:3.90.190.20 315 454 2.4E-28 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MIM_c29460 e780c25ebd18e14ac312567e41dc04ea 462 SUPERFAMILY SSF51984 1 90 5.23E-20 T 12-10-2018 MIM_c29460 e780c25ebd18e14ac312567e41dc04ea 462 Pfam PF01225 Mur ligase family, catalytic domain 2 101 1.1E-17 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MIM_c29460 e780c25ebd18e14ac312567e41dc04ea 462 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 2 454 7.9E-204 T 12-10-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 MetaCyc: PWY-7883 MIM_c29460 e780c25ebd18e14ac312567e41dc04ea 462 SUPERFAMILY SSF53244 311 450 1.83E-35 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MIM_c30930 f080659e877c73b46ad5bbc285f9b166 211 Gene3D G3DSA:3.40.1050.10 2 209 7.3E-64 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 MIM_c30930 f080659e877c73b46ad5bbc285f9b166 211 SMART SM00947 30 200 2.2E-62 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MIM_c30930 f080659e877c73b46ad5bbc285f9b166 211 SUPERFAMILY SSF53056 3 208 4.32E-56 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 MIM_c30930 f080659e877c73b46ad5bbc285f9b166 211 Pfam PF00484 Carbonic anhydrase 38 195 1.2E-46 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MIM_c14550 08120f827fdece96a98b2715afc9176b 550 Gene3D G3DSA:3.40.50.880 290 548 3.7E-102 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c14550 08120f827fdece96a98b2715afc9176b 550 Gene3D G3DSA:3.40.50.300 1 289 2.1E-128 T 12-10-2018 MIM_c14550 08120f827fdece96a98b2715afc9176b 550 Pfam PF06418 CTP synthase N-terminus 3 269 5.1E-124 T 12-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 MIM_c14550 08120f827fdece96a98b2715afc9176b 550 SUPERFAMILY SSF52317 292 545 1.35E-85 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c14550 08120f827fdece96a98b2715afc9176b 550 Hamap MF_01227 CTP synthase [pyrG]. 2 543 50.359 T 12-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 MIM_c14550 08120f827fdece96a98b2715afc9176b 550 Pfam PF00117 Glutamine amidotransferase class-I 305 537 3.9E-55 T 12-10-2018 IPR017926 Glutamine amidotransferase MIM_c14550 08120f827fdece96a98b2715afc9176b 550 SUPERFAMILY SSF52540 2 270 3.72E-120 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c14550 08120f827fdece96a98b2715afc9176b 550 TIGRFAM TIGR00337 PyrG: CTP synthase 1 538 2.7E-236 T 12-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 MIM_c10100 1b7c722cf23cc8db18991aa4c03d9ae1 609 SUPERFAMILY SSF47819 533 607 2.62E-22 T 12-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 MIM_c10100 1b7c722cf23cc8db18991aa4c03d9ae1 609 Gene3D G3DSA:3.40.50.300 2 202 1.6E-81 T 12-10-2018 MIM_c10100 1b7c722cf23cc8db18991aa4c03d9ae1 609 Pfam PF00271 Helicase conserved C-terminal domain 220 325 6.2E-15 T 12-10-2018 IPR001650 Helicase, C-terminal MIM_c10100 1b7c722cf23cc8db18991aa4c03d9ae1 609 Pfam PF16124 RecQ zinc-binding 338 399 2.5E-17 T 12-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain MIM_c10100 1b7c722cf23cc8db18991aa4c03d9ae1 609 SMART SM00341 535 609 2.9E-10 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 MIM_c10100 1b7c722cf23cc8db18991aa4c03d9ae1 609 SMART SM00956 406 513 2.1E-48 T 12-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 MIM_c10100 1b7c722cf23cc8db18991aa4c03d9ae1 609 SMART SM00487 16 212 1.7E-32 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MIM_c10100 1b7c722cf23cc8db18991aa4c03d9ae1 609 SUPERFAMILY SSF52540 202 453 4.65E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c10100 1b7c722cf23cc8db18991aa4c03d9ae1 609 Pfam PF00570 HRDC domain 539 603 1.5E-22 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 MIM_c10100 1b7c722cf23cc8db18991aa4c03d9ae1 609 SUPERFAMILY SSF52540 8 192 1.3E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c10100 1b7c722cf23cc8db18991aa4c03d9ae1 609 SMART SM00490 245 326 1.1E-24 T 12-10-2018 IPR001650 Helicase, C-terminal MIM_c10100 1b7c722cf23cc8db18991aa4c03d9ae1 609 Pfam PF00270 DEAD/DEAH box helicase 24 182 1.2E-17 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MIM_c10100 1b7c722cf23cc8db18991aa4c03d9ae1 609 Gene3D G3DSA:1.10.10.10 336 523 7.5E-50 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c10100 1b7c722cf23cc8db18991aa4c03d9ae1 609 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 9 462 6.5E-154 T 12-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 MIM_c10100 1b7c722cf23cc8db18991aa4c03d9ae1 609 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 9 605 4.1E-238 T 12-10-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 MIM_c10100 1b7c722cf23cc8db18991aa4c03d9ae1 609 Gene3D G3DSA:3.40.50.300 203 335 7.7E-39 T 12-10-2018 MIM_c10100 1b7c722cf23cc8db18991aa4c03d9ae1 609 Pfam PF09382 RQC domain 401 515 1.7E-38 T 12-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 MIM_c10100 1b7c722cf23cc8db18991aa4c03d9ae1 609 Gene3D G3DSA:1.10.150.80 537 607 5.5E-23 T 12-10-2018 MIM_c07950 ec3dadba31319c2efb23eaae8220743b 236 Gene3D G3DSA:3.90.226.10 5 228 5.4E-22 T 12-10-2018 MIM_c07950 ec3dadba31319c2efb23eaae8220743b 236 SUPERFAMILY SSF52096 59 193 3.73E-18 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c07950 ec3dadba31319c2efb23eaae8220743b 236 Pfam PF06833 Malonate decarboxylase gamma subunit (MdcE) 6 232 1.1E-60 T 12-10-2018 MIM_c25990 c7c398bf59eda7a50ce3f9c09bf65144 283 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 54 67 - T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MIM_c25990 c7c398bf59eda7a50ce3f9c09bf65144 283 Gene3D G3DSA:3.20.20.20 1 280 1.5E-109 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MIM_c25990 c7c398bf59eda7a50ce3f9c09bf65144 283 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 20 274 6.0E-98 T 12-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 MIM_c25990 c7c398bf59eda7a50ce3f9c09bf65144 283 SUPERFAMILY SSF51717 6 276 1.14E-100 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MIM_c25990 c7c398bf59eda7a50ce3f9c09bf65144 283 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 20 35 - T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MIM_c25990 c7c398bf59eda7a50ce3f9c09bf65144 283 Pfam PF00809 Pterin binding enzyme 21 260 4.1E-80 T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MIM_c18480 d24571a0efaa49983b2a0e613f325c90 196 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 9 192 1.6E-38 T 12-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 MIM_c18480 d24571a0efaa49983b2a0e613f325c90 196 Gene3D G3DSA:2.30.30.240 105 196 1.9E-18 T 12-10-2018 MIM_c18480 d24571a0efaa49983b2a0e613f325c90 196 Pfam PF01782 RimM N-terminal domain 10 100 2.1E-22 T 12-10-2018 IPR002676 RimM, N-terminal GO:0006364 MIM_c18480 d24571a0efaa49983b2a0e613f325c90 196 SUPERFAMILY SSF50346 109 195 8.63E-13 T 12-10-2018 IPR011033 PRC-barrel-like superfamily MIM_c18480 d24571a0efaa49983b2a0e613f325c90 196 SUPERFAMILY SSF50447 7 102 2.86E-17 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MIM_c18480 d24571a0efaa49983b2a0e613f325c90 196 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 8 196 23.613 T 12-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 MIM_c18480 d24571a0efaa49983b2a0e613f325c90 196 Gene3D G3DSA:2.40.30.60 7 103 1.7E-27 T 12-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 MIM_c19540 8169df912ebc641a084200dc09540f2a 310 Gene3D G3DSA:3.30.479.30 50 183 9.0E-43 T 12-10-2018 MIM_c19540 8169df912ebc641a084200dc09540f2a 310 SMART SM00244 23 181 2.3E-58 T 12-10-2018 IPR001107 Band 7 domain MIM_c19540 8169df912ebc641a084200dc09540f2a 310 PRINTS PR00721 Stomatin signature 30 52 5.1E-33 T 12-10-2018 IPR001972 Stomatin family GO:0016020 MIM_c19540 8169df912ebc641a084200dc09540f2a 310 PRINTS PR00721 Stomatin signature 133 156 5.1E-33 T 12-10-2018 IPR001972 Stomatin family GO:0016020 MIM_c19540 8169df912ebc641a084200dc09540f2a 310 PRINTS PR00721 Stomatin signature 78 99 5.1E-33 T 12-10-2018 IPR001972 Stomatin family GO:0016020 MIM_c19540 8169df912ebc641a084200dc09540f2a 310 PRINTS PR00721 Stomatin signature 176 197 5.1E-33 T 12-10-2018 IPR001972 Stomatin family GO:0016020 MIM_c19540 8169df912ebc641a084200dc09540f2a 310 PRINTS PR00721 Stomatin signature 157 175 5.1E-33 T 12-10-2018 IPR001972 Stomatin family GO:0016020 MIM_c19540 8169df912ebc641a084200dc09540f2a 310 PRINTS PR00721 Stomatin signature 113 130 5.1E-33 T 12-10-2018 IPR001972 Stomatin family GO:0016020 MIM_c19540 8169df912ebc641a084200dc09540f2a 310 Pfam PF16200 C-terminal region of band_7 247 306 8.9E-27 T 12-10-2018 IPR032435 Band 7, C-terminal extension Reactome: R-HSA-8949664 MIM_c19540 8169df912ebc641a084200dc09540f2a 310 SUPERFAMILY SSF117892 54 188 8.5E-42 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily MIM_c19540 8169df912ebc641a084200dc09540f2a 310 Pfam PF01145 SPFH domain / Band 7 family 27 196 2.8E-31 T 12-10-2018 IPR001107 Band 7 domain MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 Gene3D G3DSA:3.30.230.10 230 405 1.3E-71 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 Gene3D G3DSA:3.40.50.670 709 814 4.6E-27 T 12-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 PRINTS PR01159 DNA gyrase subunit B signature 483 492 6.1E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 PRINTS PR01159 DNA gyrase subunit B signature 785 801 6.1E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 PRINTS PR01159 DNA gyrase subunit B signature 190 205 6.1E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 PRINTS PR01159 DNA gyrase subunit B signature 325 341 6.1E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 PRINTS PR01159 DNA gyrase subunit B signature 373 387 6.1E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 PRINTS PR01159 DNA gyrase subunit B signature 205 218 6.1E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 PRINTS PR01159 DNA gyrase subunit B signature 387 407 6.1E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 PRINTS PR01159 DNA gyrase subunit B signature 229 251 6.1E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 PRINTS PR01159 DNA gyrase subunit B signature 255 273 6.1E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 PRINTS PR01159 DNA gyrase subunit B signature 769 781 6.1E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 PRINTS PR01159 DNA gyrase subunit B signature 13 23 6.1E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 SUPERFAMILY SSF54211 230 405 1.16E-56 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 Pfam PF01751 Toprim domain 432 543 2.7E-18 T 12-10-2018 IPR006171 TOPRIM domain MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 ProSitePatterns PS00177 DNA topoisomerase II signature. 435 443 - T 12-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 13 816 2.4E-298 T 12-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 PRINTS PR00418 DNA topoisomerase II family signature 281 294 2.1E-68 T 12-10-2018 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 PRINTS PR00418 DNA topoisomerase II family signature 123 137 2.1E-68 T 12-10-2018 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 PRINTS PR00418 DNA topoisomerase II family signature 537 549 2.1E-68 T 12-10-2018 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 PRINTS PR00418 DNA topoisomerase II family signature 433 447 2.1E-68 T 12-10-2018 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 PRINTS PR00418 DNA topoisomerase II family signature 748 764 2.1E-68 T 12-10-2018 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 PRINTS PR00418 DNA topoisomerase II family signature 499 515 2.1E-68 T 12-10-2018 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 PRINTS PR00418 DNA topoisomerase II family signature 78 91 2.1E-68 T 12-10-2018 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 PRINTS PR00418 DNA topoisomerase II family signature 517 534 2.1E-68 T 12-10-2018 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 PRINTS PR00418 DNA topoisomerase II family signature 43 58 2.1E-68 T 12-10-2018 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 SUPERFAMILY SSF56719 407 806 1.36E-83 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 SMART SM00387 39 185 6.7E-25 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 746 805 1.3E-29 T 12-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 Pfam PF00204 DNA gyrase B 230 403 1.4E-58 T 12-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 SUPERFAMILY SSF55874 13 225 4.32E-69 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 Gene3D G3DSA:3.30.565.10 9 229 4.5E-93 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 SMART SM00433 43 809 1.2E-261 T 12-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 10 816 99.772 T 12-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 Gene3D G3DSA:3.40.50.670 411 606 7.2E-73 T 12-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MIM_c00030 921a2c316f5d84d363ba0cd1069a5dc4 816 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 40 160 7.3E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c39000 1e394b27a517dbd77f0bf3e11940c3c1 147 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 31 145 1.3E-29 T 12-10-2018 IPR021131 Ribosomal protein L18e/L15P MIM_c39000 1e394b27a517dbd77f0bf3e11940c3c1 147 Gene3D G3DSA:3.100.10.10 72 147 3.7E-14 T 12-10-2018 MIM_c39000 1e394b27a517dbd77f0bf3e11940c3c1 147 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 5 145 9.4E-49 T 12-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c39000 1e394b27a517dbd77f0bf3e11940c3c1 147 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 6 146 19.774 T 12-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 MIM_c39000 1e394b27a517dbd77f0bf3e11940c3c1 147 SUPERFAMILY SSF52080 7 144 1.31E-46 T 12-10-2018 IPR036227 Ribosomal L18e/L15P superfamily MIM_c38950 32a5d8b03bcc54ed39f75b1968de5272 172 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 167 26.033 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 MIM_c38950 32a5d8b03bcc54ed39f75b1968de5272 172 Pfam PF01479 S4 domain 98 144 1.0E-17 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c38950 32a5d8b03bcc54ed39f75b1968de5272 172 SUPERFAMILY SSF55174 3 149 7.33E-54 T 12-10-2018 MIM_c38950 32a5d8b03bcc54ed39f75b1968de5272 172 SMART SM00363 97 159 4.2E-16 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c38950 32a5d8b03bcc54ed39f75b1968de5272 172 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 154 1.1E-60 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 MIM_c38950 32a5d8b03bcc54ed39f75b1968de5272 172 Gene3D G3DSA:1.10.1050.10 1 103 5.7E-43 T 12-10-2018 MIM_c38950 32a5d8b03bcc54ed39f75b1968de5272 172 ProSitePatterns PS00632 Ribosomal protein S4 signature. 95 119 - T 12-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c38950 32a5d8b03bcc54ed39f75b1968de5272 172 SMART SM01390 3 96 1.6E-49 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 MIM_c38950 32a5d8b03bcc54ed39f75b1968de5272 172 Gene3D G3DSA:3.10.290.10 104 169 4.0E-21 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MIM_c38950 32a5d8b03bcc54ed39f75b1968de5272 172 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 96 1.4E-32 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 MIM_c33120 5cfef34f8dbaf9b44cbf9fee859addf3 312 SUPERFAMILY SSF53474 2 294 5.4E-61 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c33120 5cfef34f8dbaf9b44cbf9fee859addf3 312 Pfam PF00561 alpha/beta hydrolase fold 35 294 1.1E-26 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c33120 5cfef34f8dbaf9b44cbf9fee859addf3 312 Gene3D G3DSA:3.40.50.1820 1 312 3.0E-102 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c33120 5cfef34f8dbaf9b44cbf9fee859addf3 312 PIRSF PIRSF006431 1 312 1.9E-136 T 12-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 MIM_c33120 5cfef34f8dbaf9b44cbf9fee859addf3 312 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 104 118 6.1E-14 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MIM_c33120 5cfef34f8dbaf9b44cbf9fee859addf3 312 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 34 42 6.1E-14 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MIM_c33120 5cfef34f8dbaf9b44cbf9fee859addf3 312 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 60 71 6.1E-14 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MIM_c33120 5cfef34f8dbaf9b44cbf9fee859addf3 312 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 6 309 2.5E-122 T 12-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 MIM_c22700 dc95684280392b0f848dbdf8bb4e427a 490 Gene3D G3DSA:1.20.210.10 7 476 6.6E-201 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c22700 dc95684280392b0f848dbdf8bb4e427a 490 SUPERFAMILY SSF81442 16 469 5.36E-123 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c22700 dc95684280392b0f848dbdf8bb4e427a 490 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 207 262 - T 12-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c22700 dc95684280392b0f848dbdf8bb4e427a 490 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 18 446 4.4E-116 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c22700 dc95684280392b0f848dbdf8bb4e427a 490 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 14 474 2.0E-228 T 12-10-2018 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 MIM_c01270 260242c50dcee065303a4a611fffa238 167 PIRSF PIRSF017306 4 163 5.2E-43 T 12-10-2018 IPR007247 Ureidoglycolate lyase GO:0000256|GO:0050385 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 MIM_c01270 260242c50dcee065303a4a611fffa238 167 Gene3D G3DSA:2.60.120.480 3 162 1.5E-57 T 12-10-2018 IPR024060 Ureidoglycolate lyase domain superfamily GO:0004848 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 MIM_c01270 260242c50dcee065303a4a611fffa238 167 SUPERFAMILY SSF51182 5 159 8.89E-55 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c01270 260242c50dcee065303a4a611fffa238 167 Pfam PF04115 Ureidoglycolate lyase 5 159 4.2E-52 T 12-10-2018 IPR007247 Ureidoglycolate lyase GO:0000256|GO:0050385 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 MIM_c05410 38cebf1726b2ebac7b06dbe9fa2267a3 429 Gene3D G3DSA:2.40.40.10 43 170 4.3E-23 T 12-10-2018 IPR036908 RlpA-like domain superfamily MIM_c05410 38cebf1726b2ebac7b06dbe9fa2267a3 429 Gene3D G3DSA:2.40.40.10 326 428 8.1E-37 T 12-10-2018 IPR036908 RlpA-like domain superfamily MIM_c05410 38cebf1726b2ebac7b06dbe9fa2267a3 429 PIRSF PIRSF019422 1 428 2.1E-127 T 12-10-2018 IPR026044 Membrane-bound lytic murein transglycosylase A MIM_c05410 38cebf1726b2ebac7b06dbe9fa2267a3 429 SMART SM00925 167 322 1.4E-85 T 12-10-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 MIM_c05410 38cebf1726b2ebac7b06dbe9fa2267a3 429 Gene3D G3DSA:2.40.240.50 171 323 6.2E-60 T 12-10-2018 MIM_c05410 38cebf1726b2ebac7b06dbe9fa2267a3 429 SUPERFAMILY SSF50685 56 422 1.5E-124 T 12-10-2018 IPR036908 RlpA-like domain superfamily MIM_c05410 38cebf1726b2ebac7b06dbe9fa2267a3 429 Pfam PF06725 3D domain 345 418 5.3E-25 T 12-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 MIM_c05410 38cebf1726b2ebac7b06dbe9fa2267a3 429 Pfam PF03562 MltA specific insert domain 77 322 1.5E-83 T 12-10-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 MIM_c02730 e89472c8a4754488296759b352ad162e 254 Gene3D G3DSA:1.10.10.10 7 81 1.9E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c02730 e89472c8a4754488296759b352ad162e 254 SUPERFAMILY SSF46785 13 84 1.8E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c02730 e89472c8a4754488296759b352ad162e 254 SUPERFAMILY SSF55781 88 252 2.09E-27 T 12-10-2018 MIM_c02730 e89472c8a4754488296759b352ad162e 254 Pfam PF09339 IclR helix-turn-helix domain 17 63 1.3E-8 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c02730 e89472c8a4754488296759b352ad162e 254 SMART SM00346 13 103 0.0098 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c02730 e89472c8a4754488296759b352ad162e 254 Pfam PF01614 Bacterial transcriptional regulator 137 242 2.1E-13 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal MIM_c02730 e89472c8a4754488296759b352ad162e 254 Gene3D G3DSA:3.30.450.40 82 253 7.6E-27 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c03440 16be87813dc676d4815a005380962455 409 SUPERFAMILY SSF89796 6 409 2.75E-140 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c03440 16be87813dc676d4815a005380962455 409 Pfam PF02515 CoA-transferase family III 8 386 1.9E-130 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 MIM_c03440 16be87813dc676d4815a005380962455 409 Gene3D G3DSA:3.40.50.10540 7 403 4.7E-143 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c03440 16be87813dc676d4815a005380962455 409 Gene3D G3DSA:3.30.1540.10 246 337 4.7E-143 T 12-10-2018 MIM_c12340 555501ce0e8c5f58ef861339be7e1c3b 230 TIGRFAM TIGR03003 ectoine_ehuD: ectoine/hydroxyectoine ABC transporter, permease protein EhuD 12 221 9.7E-90 T 12-10-2018 IPR014341 Ectoine/hydroxyectoine ABC transporter, permease protein EhuD MIM_c12340 555501ce0e8c5f58ef861339be7e1c3b 230 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 20 117 1.4E-28 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c12340 555501ce0e8c5f58ef861339be7e1c3b 230 SUPERFAMILY SSF161098 21 208 4.71E-41 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c12340 555501ce0e8c5f58ef861339be7e1c3b 230 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 42 220 5.7E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c12340 555501ce0e8c5f58ef861339be7e1c3b 230 Gene3D G3DSA:1.10.3720.10 10 224 2.4E-50 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c08170 1c767a99d9a7f1c5c0246317986eff47 627 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 46 170 5.7E-27 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ MIM_c08170 1c767a99d9a7f1c5c0246317986eff47 627 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 222 623 3.9E-89 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 MIM_c08170 1c767a99d9a7f1c5c0246317986eff47 627 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 212 621 5.4E-95 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit MIM_c16850 8a103bf346d95cfda198880590ad18b8 299 Pfam PF05175 Methyltransferase small domain 116 214 5.2E-17 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 MIM_c16850 8a103bf346d95cfda198880590ad18b8 299 Hamap MF_02125 50S ribosomal protein L3 glutamine methyltransferase [prmB]. 2 298 49.244 T 12-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 MIM_c16850 8a103bf346d95cfda198880590ad18b8 299 Gene3D G3DSA:3.40.50.150 105 277 2.9E-45 T 12-10-2018 MIM_c16850 8a103bf346d95cfda198880590ad18b8 299 Gene3D G3DSA:1.10.8.10 11 101 4.5E-5 T 12-10-2018 MIM_c16850 8a103bf346d95cfda198880590ad18b8 299 SUPERFAMILY SSF53335 12 265 3.14E-50 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c16850 8a103bf346d95cfda198880590ad18b8 299 PIRSF PIRSF037167 1 299 9.9E-123 T 12-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 MIM_c16850 8a103bf346d95cfda198880590ad18b8 299 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 202 208 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MIM_c16850 8a103bf346d95cfda198880590ad18b8 299 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 9 293 2.1E-119 T 12-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 MIM_c16850 8a103bf346d95cfda198880590ad18b8 299 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 11 275 1.3E-69 T 12-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 MIM_c03120 d0610fe2bd938a77c3cf08666ddb9a7d 330 Pfam PF00005 ABC transporter 27 184 5.6E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c03120 d0610fe2bd938a77c3cf08666ddb9a7d 330 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 300 5.0E-19 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c03120 d0610fe2bd938a77c3cf08666ddb9a7d 330 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 318 1.6E-26 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c03120 d0610fe2bd938a77c3cf08666ddb9a7d 330 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c03120 d0610fe2bd938a77c3cf08666ddb9a7d 330 SMART SM00382 35 234 1.2E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c03120 d0610fe2bd938a77c3cf08666ddb9a7d 330 SUPERFAMILY SSF52540 35 303 4.26E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c03120 d0610fe2bd938a77c3cf08666ddb9a7d 330 Gene3D G3DSA:3.40.50.300 4 327 4.3E-97 T 12-10-2018 MIM_c40440 64086f37ab17e580cdec1506a5a4cade 781 SUPERFAMILY SSF82866 202 401 4.71E-18 T 12-10-2018 MIM_c40440 64086f37ab17e580cdec1506a5a4cade 781 Gene3D G3DSA:1.20.1640.10 246 403 2.1E-5 T 12-10-2018 MIM_c40440 64086f37ab17e580cdec1506a5a4cade 781 SUPERFAMILY SSF82866 620 775 6.67E-16 T 12-10-2018 MIM_c07540 6e75417325b50f73f9cb81648a486333 383 SUPERFAMILY SSF53187 11 382 2.99E-80 T 12-10-2018 MIM_c07540 6e75417325b50f73f9cb81648a486333 383 Pfam PF07687 Peptidase dimerisation domain 184 278 4.1E-9 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain MIM_c07540 6e75417325b50f73f9cb81648a486333 383 PIRSF PIRSF005962 2 383 7.9E-120 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 MIM_c07540 6e75417325b50f73f9cb81648a486333 383 Pfam PF01546 Peptidase family M20/M25/M40 72 378 2.8E-31 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 MIM_c07540 6e75417325b50f73f9cb81648a486333 383 SUPERFAMILY SSF55031 183 288 2.49E-28 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain MIM_c07540 6e75417325b50f73f9cb81648a486333 383 Gene3D G3DSA:3.40.630.10 15 366 2.8E-125 T 12-10-2018 MIM_c07540 6e75417325b50f73f9cb81648a486333 383 Gene3D G3DSA:3.30.70.360 180 294 2.8E-125 T 12-10-2018 MIM_c07540 6e75417325b50f73f9cb81648a486333 383 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 13 370 1.0E-100 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 MIM_c38700 dc4a31bdb1dd6944fb635cd06887ce65 432 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 24 428 41.569 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MIM_c38700 dc4a31bdb1dd6944fb635cd06887ce65 432 SUPERFAMILY SSF50621 267 429 3.77E-54 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MIM_c38700 dc4a31bdb1dd6944fb635cd06887ce65 432 Gene3D G3DSA:3.20.20.10 43 287 2.7E-146 T 12-10-2018 IPR029066 PLP-binding barrel MIM_c38700 dc4a31bdb1dd6944fb635cd06887ce65 432 SUPERFAMILY SSF51419 35 294 1.21E-76 T 12-10-2018 IPR029066 PLP-binding barrel MIM_c38700 dc4a31bdb1dd6944fb635cd06887ce65 432 Gene3D G3DSA:2.40.37.10 23 425 2.7E-146 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MIM_c38700 dc4a31bdb1dd6944fb635cd06887ce65 432 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 45 291 7.2E-66 T 12-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 MIM_c38700 dc4a31bdb1dd6944fb635cd06887ce65 432 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 39 385 7.3E-27 T 12-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 MIM_c38700 dc4a31bdb1dd6944fb635cd06887ce65 432 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 18 427 8.5E-155 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MIM_c38700 dc4a31bdb1dd6944fb635cd06887ce65 432 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 86 98 3.3E-22 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MIM_c38700 dc4a31bdb1dd6944fb635cd06887ce65 432 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 385 398 3.3E-22 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MIM_c38700 dc4a31bdb1dd6944fb635cd06887ce65 432 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 199 212 3.3E-22 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MIM_c38700 dc4a31bdb1dd6944fb635cd06887ce65 432 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 282 301 3.3E-22 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MIM_c38700 dc4a31bdb1dd6944fb635cd06887ce65 432 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 66 84 3.3E-22 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MIM_c38700 dc4a31bdb1dd6944fb635cd06887ce65 432 PRINTS PR01181 Diaminopimelate decarboxylase signature 173 182 2.2E-30 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MIM_c38700 dc4a31bdb1dd6944fb635cd06887ce65 432 PRINTS PR01181 Diaminopimelate decarboxylase signature 310 328 2.2E-30 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MIM_c38700 dc4a31bdb1dd6944fb635cd06887ce65 432 PRINTS PR01181 Diaminopimelate decarboxylase signature 84 101 2.2E-30 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MIM_c38700 dc4a31bdb1dd6944fb635cd06887ce65 432 PRINTS PR01181 Diaminopimelate decarboxylase signature 395 417 2.2E-30 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MIM_c34490 633b008ed92f3e13c34ff58b8b52dc79 297 PRINTS PR00412 Epoxide hydrolase signature 236 252 5.2E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MIM_c34490 633b008ed92f3e13c34ff58b8b52dc79 297 PRINTS PR00412 Epoxide hydrolase signature 49 64 5.2E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MIM_c34490 633b008ed92f3e13c34ff58b8b52dc79 297 PRINTS PR00412 Epoxide hydrolase signature 111 124 5.2E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MIM_c34490 633b008ed92f3e13c34ff58b8b52dc79 297 PRINTS PR00412 Epoxide hydrolase signature 270 292 5.2E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MIM_c34490 633b008ed92f3e13c34ff58b8b52dc79 297 PRINTS PR00412 Epoxide hydrolase signature 29 47 5.2E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MIM_c34490 633b008ed92f3e13c34ff58b8b52dc79 297 PRINTS PR00412 Epoxide hydrolase signature 97 110 5.2E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MIM_c34490 633b008ed92f3e13c34ff58b8b52dc79 297 Pfam PF00561 alpha/beta hydrolase fold 24 277 3.2E-20 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c34490 633b008ed92f3e13c34ff58b8b52dc79 297 Gene3D G3DSA:3.40.50.1820 1 294 1.2E-75 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c34490 633b008ed92f3e13c34ff58b8b52dc79 297 SUPERFAMILY SSF53474 3 291 9.53E-53 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c21790 aac00d618f7e8ff08ed0ee71a31f4342 129 Pfam PF13411 MerR HTH family regulatory protein 21 89 2.7E-21 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MIM_c21790 aac00d618f7e8ff08ed0ee71a31f4342 129 Gene3D G3DSA:1.10.1660.10 17 92 4.4E-20 T 12-10-2018 MIM_c21790 aac00d618f7e8ff08ed0ee71a31f4342 129 SUPERFAMILY SSF46955 19 125 6.87E-19 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily MIM_c21790 aac00d618f7e8ff08ed0ee71a31f4342 129 SMART SM00422 21 91 6.1E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MIM_c02870 64a13359877a1397b18214b3340448b2 257 SUPERFAMILY SSF52343 103 254 1.83E-41 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MIM_c02870 64a13359877a1397b18214b3340448b2 257 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 51 58 8.7E-8 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MIM_c02870 64a13359877a1397b18214b3340448b2 257 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 136 145 8.7E-8 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MIM_c02870 64a13359877a1397b18214b3340448b2 257 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 111 130 8.7E-8 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MIM_c02870 64a13359877a1397b18214b3340448b2 257 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 215 223 8.7E-8 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MIM_c02870 64a13359877a1397b18214b3340448b2 257 Gene3D G3DSA:2.40.30.10 1 97 3.1E-28 T 12-10-2018 MIM_c02870 64a13359877a1397b18214b3340448b2 257 SUPERFAMILY SSF63380 4 99 1.45E-25 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MIM_c02870 64a13359877a1397b18214b3340448b2 257 Pfam PF00970 Oxidoreductase FAD-binding domain 18 91 1.8E-8 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 MIM_c02870 64a13359877a1397b18214b3340448b2 257 Pfam PF00175 Oxidoreductase NAD-binding domain 112 228 1.3E-8 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MIM_c02870 64a13359877a1397b18214b3340448b2 257 Gene3D G3DSA:3.40.50.80 100 253 8.9E-46 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MIM_c08070 8c2023673f63404bc7b798d9632b095c 417 Gene3D G3DSA:3.40.630.10 24 408 3.2E-150 T 12-10-2018 MIM_c08070 8c2023673f63404bc7b798d9632b095c 417 PIRSF PIRSF001235 10 417 1.2E-134 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 MIM_c08070 8c2023673f63404bc7b798d9632b095c 417 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 16 411 3.3E-133 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 MIM_c08070 8c2023673f63404bc7b798d9632b095c 417 Pfam PF07687 Peptidase dimerisation domain 216 319 8.4E-7 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain MIM_c08070 8c2023673f63404bc7b798d9632b095c 417 Gene3D G3DSA:3.30.70.360 218 332 3.2E-150 T 12-10-2018 MIM_c08070 8c2023673f63404bc7b798d9632b095c 417 Pfam PF01546 Peptidase family M20/M25/M40 85 410 7.1E-33 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 MIM_c08070 8c2023673f63404bc7b798d9632b095c 417 SUPERFAMILY SSF55031 218 333 9.03E-30 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain MIM_c08070 8c2023673f63404bc7b798d9632b095c 417 SUPERFAMILY SSF53187 9 412 5.71E-95 T 12-10-2018 MIM_c36170 8afbdaa6621c0f66d82f003191587991 128 Pfam PF10861 Protein of Unknown function (DUF2784) 4 111 1.8E-35 T 12-10-2018 IPR021218 Protein of unknown function DUF2784 MIM_c33350 54f73cde41b6f8b625e13c49cd1f8dc0 425 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 5 421 1.8E-159 T 12-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 MIM_c33350 54f73cde41b6f8b625e13c49cd1f8dc0 425 PIRSF PIRSF000447 2 425 3.1E-156 T 12-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 MIM_c33350 54f73cde41b6f8b625e13c49cd1f8dc0 425 SUPERFAMILY SSF53901 4 263 6.47E-69 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c33350 54f73cde41b6f8b625e13c49cd1f8dc0 425 SMART SM00825 Beta-ketoacyl synthase 7 425 7.5E-13 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MIM_c33350 54f73cde41b6f8b625e13c49cd1f8dc0 425 Gene3D G3DSA:3.40.47.10 1 266 1.4E-77 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c33350 54f73cde41b6f8b625e13c49cd1f8dc0 425 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 258 1.2E-53 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MIM_c33350 54f73cde41b6f8b625e13c49cd1f8dc0 425 SUPERFAMILY SSF53901 226 424 4.61E-64 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c33350 54f73cde41b6f8b625e13c49cd1f8dc0 425 Gene3D G3DSA:3.40.47.10 272 425 3.3E-55 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c33350 54f73cde41b6f8b625e13c49cd1f8dc0 425 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 267 379 2.2E-35 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MIM_c33350 54f73cde41b6f8b625e13c49cd1f8dc0 425 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 165 181 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site MIM_c38680 56382ba5e47ff102bd31574842fe8723 804 SUPERFAMILY SSF56601 221 750 2.2E-113 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MIM_c38680 56382ba5e47ff102bd31574842fe8723 804 Gene3D G3DSA:2.40.50.140 366 436 1.9E-16 T 12-10-2018 MIM_c38680 56382ba5e47ff102bd31574842fe8723 804 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 75 729 1.8E-176 T 12-10-2018 MIM_c38680 56382ba5e47ff102bd31574842fe8723 804 Gene3D G3DSA:1.10.3810.10 60 255 3.1E-74 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c38680 56382ba5e47ff102bd31574842fe8723 804 Pfam PF00905 Penicillin binding protein transpeptidase domain 440 691 7.7E-40 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MIM_c38680 56382ba5e47ff102bd31574842fe8723 804 SUPERFAMILY SSF53955 52 264 4.5E-75 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily MIM_c38680 56382ba5e47ff102bd31574842fe8723 804 Pfam PF00912 Transglycosylase 67 239 2.1E-61 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c38680 56382ba5e47ff102bd31574842fe8723 804 Pfam PF17092 Penicillin-binding protein OB-like domain 331 438 5.0E-14 T 12-10-2018 IPR031376 Penicillin-binding protein, OB-like domain KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c13440 1c739777f063d4ebc4c9ff40ce8a2f5c 600 Pfam PF00005 ABC transporter 371 520 1.0E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c13440 1c739777f063d4ebc4c9ff40ce8a2f5c 600 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c13440 1c739777f063d4ebc4c9ff40ce8a2f5c 600 Pfam PF00664 ABC transporter transmembrane region 36 309 6.4E-37 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MIM_c13440 1c739777f063d4ebc4c9ff40ce8a2f5c 600 SMART SM00382 380 566 9.3E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c13440 1c739777f063d4ebc4c9ff40ce8a2f5c 600 Gene3D G3DSA:3.40.50.300 346 599 2.3E-96 T 12-10-2018 MIM_c13440 1c739777f063d4ebc4c9ff40ce8a2f5c 600 SUPERFAMILY SSF90123 25 343 4.84E-62 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MIM_c13440 1c739777f063d4ebc4c9ff40ce8a2f5c 600 SUPERFAMILY SSF52540 347 591 5.43E-95 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c13440 1c739777f063d4ebc4c9ff40ce8a2f5c 600 Gene3D G3DSA:1.20.1560.10 28 344 2.9E-112 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MIM_c05790 5cd359cb33b60f2c3e38e8279afa2b28 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 6.4E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c05790 5cd359cb33b60f2c3e38e8279afa2b28 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.0E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c05790 5cd359cb33b60f2c3e38e8279afa2b28 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.0E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c05790 5cd359cb33b60f2c3e38e8279afa2b28 188 SUPERFAMILY SSF46689 4 82 2.29E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c05790 5cd359cb33b60f2c3e38e8279afa2b28 188 Gene3D G3DSA:1.10.357.10 3 186 4.0E-40 T 12-10-2018 MIM_c05790 5cd359cb33b60f2c3e38e8279afa2b28 188 SUPERFAMILY SSF48498 96 184 3.71E-8 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MIM_c16420 c18eb1683c1631005061ee3ed67563bc 181 Gene3D G3DSA:3.30.420.10 2 181 5.3E-70 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MIM_c16420 c18eb1683c1631005061ee3ed67563bc 181 Pfam PF00929 Exonuclease 9 170 3.8E-31 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MIM_c16420 c18eb1683c1631005061ee3ed67563bc 181 SUPERFAMILY SSF53098 2 180 6.96E-47 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily MIM_c16420 c18eb1683c1631005061ee3ed67563bc 181 SMART SM00479 7 180 2.1E-24 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MIM_c16420 c18eb1683c1631005061ee3ed67563bc 181 Hamap MF_00045 Oligoribonuclease [orn]. 3 181 42.147 T 12-10-2018 IPR022894 Oligoribonuclease GO:0000175 MIM_c36580 48d034e2117dc1605e1514c0c251ea10 349 Pfam PF01515 Phosphate acetyl/butaryl transferase 4 327 2.0E-115 T 12-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MIM_c36580 48d034e2117dc1605e1514c0c251ea10 349 SUPERFAMILY SSF53659 2 331 8.22E-87 T 12-10-2018 MIM_c36580 48d034e2117dc1605e1514c0c251ea10 349 Gene3D G3DSA:3.40.50.10750 142 303 1.3E-125 T 12-10-2018 MIM_c36580 48d034e2117dc1605e1514c0c251ea10 349 PIRSF PIRSF000428 1 334 1.4E-105 T 12-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MIM_c36580 48d034e2117dc1605e1514c0c251ea10 349 Gene3D G3DSA:3.40.50.10950 9 330 1.3E-125 T 12-10-2018 MIM_c36580 48d034e2117dc1605e1514c0c251ea10 349 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 18 326 7.6E-110 T 12-10-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MIM_c38240 d22169c0b801608aa5c51d7ddccc8fe2 190 Pfam PF03551 Transcriptional regulator PadR-like family 40 108 1.2E-13 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal MIM_c38240 d22169c0b801608aa5c51d7ddccc8fe2 190 SUPERFAMILY SSF46785 36 167 6.24E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c38240 d22169c0b801608aa5c51d7ddccc8fe2 190 Gene3D G3DSA:1.10.10.10 24 133 1.2E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c26700 1556b12a84605f42b0dc0b8e21e5a5c0 806 Pfam PF04453 Organic solvent tolerance protein 292 711 9.0E-79 T 12-10-2018 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 MIM_c26700 1556b12a84605f42b0dc0b8e21e5a5c0 806 Gene3D G3DSA:2.60.450.10 45 147 1.2E-5 T 12-10-2018 MIM_c26700 1556b12a84605f42b0dc0b8e21e5a5c0 806 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 9 773 18.964 T 12-10-2018 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 MIM_c00990 2c4c2d5ce8efffd2aa98c5653f9b3b8f 263 SUPERFAMILY SSF51197 2 245 5.59E-54 T 12-10-2018 MIM_c00990 2c4c2d5ce8efffd2aa98c5653f9b3b8f 263 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 11 217 1.1E-32 T 12-10-2018 IPR008775 Phytanoyl-CoA dioxygenase MIM_c00990 2c4c2d5ce8efffd2aa98c5653f9b3b8f 263 Gene3D G3DSA:2.60.120.620 1 258 2.3E-85 T 12-10-2018 MIM_c09640 b27e3f7691263aaad19632a4182b0f35 91 Gene3D G3DSA:1.10.245.10 10 91 1.3E-29 T 12-10-2018 IPR036885 SWIB/MDM2 domain superfamily MIM_c09640 b27e3f7691263aaad19632a4182b0f35 91 Pfam PF02201 SWIB/MDM2 domain 18 90 4.3E-30 T 12-10-2018 IPR003121 SWIB/MDM2 domain GO:0005515 MIM_c09640 b27e3f7691263aaad19632a4182b0f35 91 SMART SM00151 16 91 2.7E-36 T 12-10-2018 IPR019835 SWIB domain Reactome: R-HSA-3214858|Reactome: R-HSA-8939243 MIM_c09640 b27e3f7691263aaad19632a4182b0f35 91 SUPERFAMILY SSF47592 11 90 2.62E-29 T 12-10-2018 IPR036885 SWIB/MDM2 domain superfamily MIM_c01240 f410c32be3757fbd5621b77431c318ec 308 Gene3D G3DSA:3.40.190.10 91 294 9.5E-64 T 12-10-2018 MIM_c01240 f410c32be3757fbd5621b77431c318ec 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 3.5E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c01240 f410c32be3757fbd5621b77431c318ec 308 Pfam PF03466 LysR substrate binding domain 89 295 7.6E-41 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c01240 f410c32be3757fbd5621b77431c318ec 308 Gene3D G3DSA:1.10.10.10 3 88 5.8E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c01240 f410c32be3757fbd5621b77431c318ec 308 SUPERFAMILY SSF53850 90 299 2.71E-43 T 12-10-2018 MIM_c01240 f410c32be3757fbd5621b77431c318ec 308 SUPERFAMILY SSF46785 4 111 1.18E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c01240 f410c32be3757fbd5621b77431c318ec 308 Gene3D G3DSA:3.40.190.10 163 267 9.5E-64 T 12-10-2018 MIM_c08330 52f1db529e7c70046a0e711b92781002 424 Gene3D G3DSA:3.30.70.420 111 220 3.5E-135 T 12-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MIM_c08330 52f1db529e7c70046a0e711b92781002 424 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 17 381 9.4E-115 T 12-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MIM_c08330 52f1db529e7c70046a0e711b92781002 424 SUPERFAMILY SSF56542 7 421 2.49E-104 T 12-10-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MIM_c08330 52f1db529e7c70046a0e711b92781002 424 SUPERFAMILY SSF55035 113 219 5.75E-30 T 12-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MIM_c08330 52f1db529e7c70046a0e711b92781002 424 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 176 190 - T 12-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MIM_c08330 52f1db529e7c70046a0e711b92781002 424 TIGRFAM TIGR00532 HMG_CoA_R_NAD: hydroxymethylglutaryl-CoA reductase, degradative 4 381 1.2E-140 T 12-10-2018 IPR004553 Hydroxymethylglutaryl-CoA reductase, bacterial-type GO:0015936|GO:0016616|GO:0050662 MIM_c08330 52f1db529e7c70046a0e711b92781002 424 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 51 72 2.7E-8 T 12-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MIM_c08330 52f1db529e7c70046a0e711b92781002 424 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 308 329 2.7E-8 T 12-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MIM_c08330 52f1db529e7c70046a0e711b92781002 424 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 78 98 2.7E-8 T 12-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MIM_c08330 52f1db529e7c70046a0e711b92781002 424 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 174 192 2.7E-8 T 12-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MIM_c08330 52f1db529e7c70046a0e711b92781002 424 Gene3D G3DSA:1.10.8.660 371 421 1.1E-14 T 12-10-2018 MIM_c08330 52f1db529e7c70046a0e711b92781002 424 ProSitePatterns PS01192 Hydroxymethylglutaryl-coenzyme A reductases signature 3. 366 379 - T 12-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MIM_c08330 52f1db529e7c70046a0e711b92781002 424 Gene3D G3DSA:3.90.770.10 16 367 3.5E-135 T 12-10-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MIM_c08330 52f1db529e7c70046a0e711b92781002 424 ProSitePatterns PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 320 327 - T 12-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MIM_c10700 24f266a02b0f20fec9d904dd34ce91b6 442 Gene3D G3DSA:1.10.860.10 2 149 1.7E-38 T 12-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal MIM_c10700 24f266a02b0f20fec9d904dd34ce91b6 442 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 5 422 3.3E-118 T 12-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 MIM_c10700 24f266a02b0f20fec9d904dd34ce91b6 442 SUPERFAMILY SSF48024 3 103 1.1E-25 T 12-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 MIM_c10700 24f266a02b0f20fec9d904dd34ce91b6 442 SMART SM00382 186 371 2.1E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c10700 24f266a02b0f20fec9d904dd34ce91b6 442 Pfam PF00772 DnaB-like helicase N terminal domain 4 95 3.6E-24 T 12-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 MIM_c10700 24f266a02b0f20fec9d904dd34ce91b6 442 Pfam PF03796 DnaB-like helicase C terminal domain 170 420 1.5E-78 T 12-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 MIM_c10700 24f266a02b0f20fec9d904dd34ce91b6 442 Gene3D G3DSA:3.40.50.300 153 425 3.4E-82 T 12-10-2018 MIM_c10700 24f266a02b0f20fec9d904dd34ce91b6 442 SUPERFAMILY SSF52540 168 412 2.35E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c29280 f3ce1bf093720ae91a3827acb58cef4e 351 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 164 322 2.3E-21 T 12-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MIM_c29280 f3ce1bf093720ae91a3827acb58cef4e 351 SUPERFAMILY SSF55347 155 319 8.18E-52 T 12-10-2018 MIM_c29280 f3ce1bf093720ae91a3827acb58cef4e 351 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 9 146 1.0E-35 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MIM_c29280 f3ce1bf093720ae91a3827acb58cef4e 351 SMART SM00859 9 147 6.3E-58 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MIM_c29280 f3ce1bf093720ae91a3827acb58cef4e 351 Gene3D G3DSA:3.40.50.720 9 337 3.5E-130 T 12-10-2018 MIM_c29280 f3ce1bf093720ae91a3827acb58cef4e 351 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 150 166 - T 12-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MIM_c29280 f3ce1bf093720ae91a3827acb58cef4e 351 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 8 345 41.814 T 12-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MIM_c29280 f3ce1bf093720ae91a3827acb58cef4e 351 SUPERFAMILY SSF51735 8 179 4.32E-54 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c29280 f3ce1bf093720ae91a3827acb58cef4e 351 Gene3D G3DSA:3.30.360.10 153 319 3.5E-130 T 12-10-2018 MIM_c29280 f3ce1bf093720ae91a3827acb58cef4e 351 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 8 351 1.6E-128 T 12-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MIM_c19920 00814468e9047438907430bf0a8502d4 304 SUPERFAMILY SSF53850 92 283 1.37E-28 T 12-10-2018 MIM_c19920 00814468e9047438907430bf0a8502d4 304 Gene3D G3DSA:1.10.10.10 2 84 1.7E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c19920 00814468e9047438907430bf0a8502d4 304 Pfam PF03466 LysR substrate binding domain 92 280 1.2E-27 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c19920 00814468e9047438907430bf0a8502d4 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 1.3E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c19920 00814468e9047438907430bf0a8502d4 304 SUPERFAMILY SSF46785 4 111 1.72E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c19920 00814468e9047438907430bf0a8502d4 304 Gene3D G3DSA:3.40.190.10 98 272 8.5E-21 T 12-10-2018 MIM_c19920 00814468e9047438907430bf0a8502d4 304 Gene3D G3DSA:3.40.190.10 166 268 8.5E-21 T 12-10-2018 MIM_c19920 00814468e9047438907430bf0a8502d4 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c19920 00814468e9047438907430bf0a8502d4 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c19920 00814468e9047438907430bf0a8502d4 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c38390 c2b6a760fdf2634753c540f51ea193c6 313 Gene3D G3DSA:3.40.190.10 91 293 4.7E-48 T 12-10-2018 MIM_c38390 c2b6a760fdf2634753c540f51ea193c6 313 Pfam PF03466 LysR substrate binding domain 88 295 4.3E-31 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c38390 c2b6a760fdf2634753c540f51ea193c6 313 SUPERFAMILY SSF46785 3 112 5.54E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c38390 c2b6a760fdf2634753c540f51ea193c6 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.9E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c38390 c2b6a760fdf2634753c540f51ea193c6 313 Gene3D G3DSA:1.10.10.10 3 89 2.5E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c38390 c2b6a760fdf2634753c540f51ea193c6 313 Gene3D G3DSA:3.40.190.10 163 264 4.7E-48 T 12-10-2018 MIM_c38390 c2b6a760fdf2634753c540f51ea193c6 313 SUPERFAMILY SSF53850 89 298 1.38E-33 T 12-10-2018 MIM_c38650 f3aab846fdbdcdfd2a19571414b3d1f0 376 Pfam PF13286 Phosphohydrolase-associated domain 286 372 1.3E-28 T 12-10-2018 IPR026875 Phosphohydrolase-associated domain MIM_c38650 f3aab846fdbdcdfd2a19571414b3d1f0 376 SUPERFAMILY SSF109604 17 375 3.39E-88 T 12-10-2018 MIM_c38650 f3aab846fdbdcdfd2a19571414b3d1f0 376 SMART SM00471 62 210 1.0E-9 T 12-10-2018 IPR003607 HD/PDEase domain MIM_c38650 f3aab846fdbdcdfd2a19571414b3d1f0 376 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 29 171 3.2E-55 T 12-10-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 MIM_c38650 f3aab846fdbdcdfd2a19571414b3d1f0 376 Pfam PF01966 HD domain 66 199 6.7E-13 T 12-10-2018 IPR006674 HD domain MIM_c38650 f3aab846fdbdcdfd2a19571414b3d1f0 376 Gene3D G3DSA:1.10.3210.10 1 375 3.8E-130 T 12-10-2018 MIM_c38650 f3aab846fdbdcdfd2a19571414b3d1f0 376 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 6 374 37.456 T 12-10-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 MIM_c40980 65204c96e2ba616da68c96f777bf4283 482 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 83 5.3E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c40980 65204c96e2ba616da68c96f777bf4283 482 Gene3D G3DSA:3.40.640.10 108 466 1.4E-107 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c40980 65204c96e2ba616da68c96f777bf4283 482 SUPERFAMILY SSF53383 109 473 2.16E-80 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c40980 65204c96e2ba616da68c96f777bf4283 482 Gene3D G3DSA:1.10.10.10 16 105 2.4E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c40980 65204c96e2ba616da68c96f777bf4283 482 SMART SM00345 24 83 1.7E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c40980 65204c96e2ba616da68c96f777bf4283 482 SUPERFAMILY SSF46785 13 85 2.23E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c40980 65204c96e2ba616da68c96f777bf4283 482 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 3.6E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c40980 65204c96e2ba616da68c96f777bf4283 482 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 3.6E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c40980 65204c96e2ba616da68c96f777bf4283 482 Pfam PF00155 Aminotransferase class I and II 147 410 4.8E-21 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MIM_c25880 b8b20df030befe308b5bce8f1c4c110c 788 SUPERFAMILY SSF81665 226 464 9.94E-15 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 MIM_c25880 b8b20df030befe308b5bce8f1c4c110c 788 Gene3D G3DSA:3.30.70.100 1 76 4.8E-8 T 12-10-2018 MIM_c25880 b8b20df030befe308b5bce8f1c4c110c 788 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 478 484 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MIM_c25880 b8b20df030befe308b5bce8f1c4c110c 788 SUPERFAMILY SSF56784 475 777 7.33E-49 T 12-10-2018 IPR036412 HAD-like superfamily MIM_c25880 b8b20df030befe308b5bce8f1c4c110c 788 Gene3D G3DSA:3.40.50.1000 457 730 7.6E-76 T 12-10-2018 IPR023214 HAD superfamily MIM_c25880 b8b20df030befe308b5bce8f1c4c110c 788 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 225 780 1.7E-166 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MIM_c25880 b8b20df030befe308b5bce8f1c4c110c 788 Gene3D G3DSA:3.40.1110.10 487 608 7.6E-76 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MIM_c25880 b8b20df030befe308b5bce8f1c4c110c 788 SUPERFAMILY SSF55008 10 74 7.2E-12 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 MIM_c25880 b8b20df030befe308b5bce8f1c4c110c 788 Pfam PF00702 haloacid dehalogenase-like hydrolase 475 691 4.4E-33 T 12-10-2018 MIM_c25880 b8b20df030befe308b5bce8f1c4c110c 788 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 677 693 1.4E-5 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MIM_c25880 b8b20df030befe308b5bce8f1c4c110c 788 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 648 664 1.4E-5 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MIM_c25880 b8b20df030befe308b5bce8f1c4c110c 788 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 709 734 1.4E-5 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MIM_c25880 b8b20df030befe308b5bce8f1c4c110c 788 Pfam PF00122 E1-E2 ATPase 276 455 2.0E-52 T 12-10-2018 MIM_c25880 b8b20df030befe308b5bce8f1c4c110c 788 SUPERFAMILY SSF81653 278 374 8.11E-23 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 MIM_c25880 b8b20df030befe308b5bce8f1c4c110c 788 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 701 713 1.2E-21 T 12-10-2018 MIM_c25880 b8b20df030befe308b5bce8f1c4c110c 788 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 623 633 1.2E-21 T 12-10-2018 MIM_c25880 b8b20df030befe308b5bce8f1c4c110c 788 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 677 696 1.2E-21 T 12-10-2018 MIM_c25880 b8b20df030befe308b5bce8f1c4c110c 788 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 325 339 1.2E-21 T 12-10-2018 MIM_c25880 b8b20df030befe308b5bce8f1c4c110c 788 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 476 490 1.2E-21 T 12-10-2018 MIM_c25880 b8b20df030befe308b5bce8f1c4c110c 788 Gene3D G3DSA:2.70.150.20 269 380 6.6E-31 T 12-10-2018 MIM_c25880 b8b20df030befe308b5bce8f1c4c110c 788 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 248 514 3.1E-36 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MIM_c25880 b8b20df030befe308b5bce8f1c4c110c 788 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 575 755 4.8E-38 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MIM_c37860 7b57de26f429830dc5ed2ea55d53f1b3 653 Pfam PF04632 Fusaric acid resistance protein family 22 637 1.8E-66 T 12-10-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0022857|GO:0055085 MIM_c09400 68928a098024667ee94b27592db15a06 443 Pfam PF13379 NMT1-like family 68 318 1.4E-102 T 12-10-2018 MIM_c09400 68928a098024667ee94b27592db15a06 443 Gene3D G3DSA:3.40.190.10 161 432 1.5E-125 T 12-10-2018 MIM_c09400 68928a098024667ee94b27592db15a06 443 SUPERFAMILY SSF53850 71 306 3.8E-31 T 12-10-2018 MIM_c09400 68928a098024667ee94b27592db15a06 443 Gene3D G3DSA:3.40.190.10 75 427 1.5E-125 T 12-10-2018 MIM_c17850 14c65e9b15abc27e8d14fdc6aa76994f 135 SUPERFAMILY SSF54919 1 134 1.06E-55 T 12-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MIM_c17850 14c65e9b15abc27e8d14fdc6aa76994f 135 SMART SM00562 3 135 9.7E-80 T 12-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MIM_c17850 14c65e9b15abc27e8d14fdc6aa76994f 135 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 5.0E-40 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MIM_c17850 14c65e9b15abc27e8d14fdc6aa76994f 135 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 5.0E-40 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MIM_c17850 14c65e9b15abc27e8d14fdc6aa76994f 135 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 5.0E-40 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MIM_c17850 14c65e9b15abc27e8d14fdc6aa76994f 135 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 5.0E-40 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MIM_c17850 14c65e9b15abc27e8d14fdc6aa76994f 135 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 5.0E-40 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MIM_c17850 14c65e9b15abc27e8d14fdc6aa76994f 135 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 135 33.249 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MIM_c17850 14c65e9b15abc27e8d14fdc6aa76994f 135 Gene3D G3DSA:3.30.70.141 1 135 2.1E-58 T 12-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MIM_c17850 14c65e9b15abc27e8d14fdc6aa76994f 135 Pfam PF00334 Nucleoside diphosphate kinase 4 134 3.5E-55 T 12-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MIM_c04340 2f12012866498456e576f3955bc71ce2 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 319 1.3E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c04340 2f12012866498456e576f3955bc71ce2 324 SUPERFAMILY SSF53850 105 278 7.48E-11 T 12-10-2018 MIM_c04340 2f12012866498456e576f3955bc71ce2 324 Gene3D G3DSA:3.40.190.10 128 250 1.8E-102 T 12-10-2018 MIM_c04340 2f12012866498456e576f3955bc71ce2 324 Gene3D G3DSA:3.40.190.150 30 313 1.8E-102 T 12-10-2018 MIM_c04340 2f12012866498456e576f3955bc71ce2 324 PIRSF PIRSF017082 4 323 5.4E-81 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c18230 3b3c5f862df302054f3f2731089cf742 159 Pfam PF02631 RecX family 40 155 3.5E-26 T 12-10-2018 IPR003783 Regulatory protein RecX GO:0006282 MIM_c18230 3b3c5f862df302054f3f2731089cf742 159 Gene3D G3DSA:1.10.10.10 110 158 1.3E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c18230 3b3c5f862df302054f3f2731089cf742 159 Gene3D G3DSA:1.10.10.10 16 62 9.6E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c18230 3b3c5f862df302054f3f2731089cf742 159 Hamap MF_01114 Regulatory protein RecX [recX]. 14 159 12.471 T 12-10-2018 IPR003783 Regulatory protein RecX GO:0006282 MIM_24p00230 e765ef912026351b0b3e736166d33ce0 215 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 190 9.9E-15 T 12-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain MIM_24p00230 e765ef912026351b0b3e736166d33ce0 215 PIRSF PIRSF009320 1 215 2.3E-36 T 12-10-2018 MIM_24p00230 e765ef912026351b0b3e736166d33ce0 215 SUPERFAMILY SSF52540 2 214 1.9E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_24p00230 e765ef912026351b0b3e736166d33ce0 215 Gene3D G3DSA:3.40.50.300 1 215 1.9E-41 T 12-10-2018 MIM_c06140 86a513f1320fe0359e684321f39fad9c 234 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 40 53 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MIM_c06140 86a513f1320fe0359e684321f39fad9c 234 Pfam PF00005 ABC transporter 27 181 1.1E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c06140 86a513f1320fe0359e684321f39fad9c 234 SMART SM00382 36 229 1.5E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c06140 86a513f1320fe0359e684321f39fad9c 234 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c06140 86a513f1320fe0359e684321f39fad9c 234 Gene3D G3DSA:3.40.50.300 1 232 1.9E-49 T 12-10-2018 MIM_c06140 86a513f1320fe0359e684321f39fad9c 234 SUPERFAMILY SSF52540 3 226 6.34E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c06140 86a513f1320fe0359e684321f39fad9c 234 TIGRFAM TIGR02324 CP_lyasePhnL: phosphonate C-P lyase system protein PhnL 5 225 5.0E-106 T 12-10-2018 IPR012701 Phosphonate C-P lyase system, PhnL KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 MIM_c32770 2dc272952d1d8106f60e77a276b8f50e 450 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 64 79 2.2E-35 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 MIM_c32770 2dc272952d1d8106f60e77a276b8f50e 450 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 107 127 2.2E-35 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 MIM_c32770 2dc272952d1d8106f60e77a276b8f50e 450 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 195 217 2.2E-35 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 MIM_c32770 2dc272952d1d8106f60e77a276b8f50e 450 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 153 179 2.2E-35 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 MIM_c32770 2dc272952d1d8106f60e77a276b8f50e 450 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 85 105 2.2E-35 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 MIM_c32770 2dc272952d1d8106f60e77a276b8f50e 450 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 34 59 2.2E-35 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 MIM_c32770 2dc272952d1d8106f60e77a276b8f50e 450 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 204 439 5.6E-11 T 12-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 MIM_c32770 2dc272952d1d8106f60e77a276b8f50e 450 Gene3D G3DSA:3.90.380.10 27 439 2.8E-97 T 12-10-2018 MIM_c32770 2dc272952d1d8106f60e77a276b8f50e 450 SUPERFAMILY SSF50022 20 168 2.49E-42 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MIM_c32770 2dc272952d1d8106f60e77a276b8f50e 450 SUPERFAMILY SSF55961 169 443 1.1E-50 T 12-10-2018 MIM_c32770 2dc272952d1d8106f60e77a276b8f50e 450 Gene3D G3DSA:2.102.10.10 47 178 2.8E-97 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MIM_c32770 2dc272952d1d8106f60e77a276b8f50e 450 Pfam PF00355 Rieske [2Fe-2S] domain 49 133 5.5E-19 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MIM_c21370 9336f761c38d25c7f713162230d5b5b9 470 Gene3D G3DSA:1.10.275.10 39 243 2.3E-187 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal MIM_c21370 9336f761c38d25c7f713162230d5b5b9 470 Gene3D G3DSA:1.10.40.30 374 446 2.3E-187 T 12-10-2018 MIM_c21370 9336f761c38d25c7f713162230d5b5b9 470 Pfam PF14698 Argininosuccinate lyase C-terminal 377 444 2.6E-26 T 12-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MIM_c21370 9336f761c38d25c7f713162230d5b5b9 470 TIGRFAM TIGR00838 argH: argininosuccinate lyase 18 465 8.6E-185 T 12-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MIM_c21370 9336f761c38d25c7f713162230d5b5b9 470 Hamap MF_00006 Argininosuccinate lyase [argH]. 16 467 43.022 T 12-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MIM_c21370 9336f761c38d25c7f713162230d5b5b9 470 ProSitePatterns PS00163 Fumarate lyases signature. 289 298 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MIM_c21370 9336f761c38d25c7f713162230d5b5b9 470 SUPERFAMILY SSF48557 18 464 5.34E-150 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 MIM_c21370 9336f761c38d25c7f713162230d5b5b9 470 PRINTS PR00145 Argininosuccinate lyase family signature 115 137 9.0E-68 T 12-10-2018 MIM_c21370 9336f761c38d25c7f713162230d5b5b9 470 PRINTS PR00145 Argininosuccinate lyase family signature 289 305 9.0E-68 T 12-10-2018 MIM_c21370 9336f761c38d25c7f713162230d5b5b9 470 PRINTS PR00145 Argininosuccinate lyase family signature 156 176 9.0E-68 T 12-10-2018 MIM_c21370 9336f761c38d25c7f713162230d5b5b9 470 PRINTS PR00145 Argininosuccinate lyase family signature 324 343 9.0E-68 T 12-10-2018 MIM_c21370 9336f761c38d25c7f713162230d5b5b9 470 PRINTS PR00145 Argininosuccinate lyase family signature 207 223 9.0E-68 T 12-10-2018 MIM_c21370 9336f761c38d25c7f713162230d5b5b9 470 PRINTS PR00145 Argininosuccinate lyase family signature 245 269 9.0E-68 T 12-10-2018 MIM_c21370 9336f761c38d25c7f713162230d5b5b9 470 Gene3D G3DSA:1.20.200.10 133 460 2.3E-187 T 12-10-2018 MIM_c21370 9336f761c38d25c7f713162230d5b5b9 470 Pfam PF00206 Lyase 21 314 5.2E-75 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal MIM_c21370 9336f761c38d25c7f713162230d5b5b9 470 PRINTS PR00149 Fumarate lyase superfamily signature 245 272 4.2E-31 T 12-10-2018 IPR000362 Fumarate lyase family MIM_c21370 9336f761c38d25c7f713162230d5b5b9 470 PRINTS PR00149 Fumarate lyase superfamily signature 116 134 4.2E-31 T 12-10-2018 IPR000362 Fumarate lyase family MIM_c21370 9336f761c38d25c7f713162230d5b5b9 470 PRINTS PR00149 Fumarate lyase superfamily signature 289 305 4.2E-31 T 12-10-2018 IPR000362 Fumarate lyase family MIM_c21370 9336f761c38d25c7f713162230d5b5b9 470 PRINTS PR00149 Fumarate lyase superfamily signature 161 179 4.2E-31 T 12-10-2018 IPR000362 Fumarate lyase family MIM_c17940 615a5a84638f239b804d82b2bb105c11 80 Gene3D G3DSA:2.30.30.100 1 76 2.5E-33 T 12-10-2018 MIM_c17940 615a5a84638f239b804d82b2bb105c11 80 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 6 65 4.0E-29 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 MIM_c17940 615a5a84638f239b804d82b2bb105c11 80 SUPERFAMILY SSF50182 8 70 3.27E-24 T 12-10-2018 IPR010920 LSM domain superfamily MIM_c17940 615a5a84638f239b804d82b2bb105c11 80 Pfam PF17209 Hfq protein 8 69 1.3E-31 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 MIM_c17940 615a5a84638f239b804d82b2bb105c11 80 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 4 65 28.21 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 MIM_c36500 53a52ecd31735074a8e1fffcee3584f1 612 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 14 612 50.17 T 12-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 MIM_c36500 53a52ecd31735074a8e1fffcee3584f1 612 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 249 609 2.1E-163 T 12-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 MIM_c36500 53a52ecd31735074a8e1fffcee3584f1 612 SUPERFAMILY SSF53795 249 610 7.78E-151 T 12-10-2018 MIM_c36500 53a52ecd31735074a8e1fffcee3584f1 612 Gene3D G3DSA:3.90.228.20 249 604 1.9E-262 T 12-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 MIM_c36500 53a52ecd31735074a8e1fffcee3584f1 612 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 26 245 1.4E-106 T 12-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 MIM_c36500 53a52ecd31735074a8e1fffcee3584f1 612 Gene3D G3DSA:2.170.8.10 61 403 1.9E-262 T 12-10-2018 MIM_c36500 53a52ecd31735074a8e1fffcee3584f1 612 SUPERFAMILY SSF68923 14 248 1.1E-102 T 12-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 MIM_c36500 53a52ecd31735074a8e1fffcee3584f1 612 Gene3D G3DSA:3.40.449.10 25 248 1.9E-262 T 12-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 MIM_c36500 53a52ecd31735074a8e1fffcee3584f1 612 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 273 281 - T 12-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 MIM_c36500 53a52ecd31735074a8e1fffcee3584f1 612 PIRSF PIRSF001348 5 612 1.6E-277 T 12-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 MIM_c26680 72e15597817222bdf4905d3606d8ae6e 259 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 5 252 5.2E-84 T 12-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 MIM_c26680 72e15597817222bdf4905d3606d8ae6e 259 SUPERFAMILY SSF53335 4 254 1.77E-71 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c26680 72e15597817222bdf4905d3606d8ae6e 259 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 4 253 54.15 T 12-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 MIM_c26680 72e15597817222bdf4905d3606d8ae6e 259 Pfam PF00398 Ribosomal RNA adenine dimethylase 4 252 4.1E-59 T 12-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm MIM_c26680 72e15597817222bdf4905d3606d8ae6e 259 Gene3D G3DSA:1.10.8.100 194 257 9.3E-17 T 12-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 MIM_c26680 72e15597817222bdf4905d3606d8ae6e 259 SMART SM00650 20 188 8.2E-77 T 12-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 MIM_c26680 72e15597817222bdf4905d3606d8ae6e 259 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 36 63 - T 12-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 MIM_c26680 72e15597817222bdf4905d3606d8ae6e 259 Gene3D G3DSA:3.40.50.150 2 187 1.2E-61 T 12-10-2018 MIM_c03500 bdb9acd46020d19c2fe72781b940080d 279 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 38 261 29.683 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 MIM_c03500 bdb9acd46020d19c2fe72781b940080d 279 Gene3D G3DSA:3.20.20.10 16 273 4.0E-87 T 12-10-2018 IPR029066 PLP-binding barrel MIM_c03500 bdb9acd46020d19c2fe72781b940080d 279 Pfam PF01168 Alanine racemase, N-terminal domain 39 262 3.7E-25 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MIM_c03500 bdb9acd46020d19c2fe72781b940080d 279 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 35 262 5.4E-60 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 MIM_c03500 bdb9acd46020d19c2fe72781b940080d 279 SUPERFAMILY SSF51419 30 260 6.15E-74 T 12-10-2018 IPR029066 PLP-binding barrel MIM_c03500 bdb9acd46020d19c2fe72781b940080d 279 PIRSF PIRSF004848 24 268 1.9E-70 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 MIM_c09100 fb0288a85a45ae3ec003b12b6d782710 302 PIRSF PIRSF003097 2 302 1.7E-48 T 12-10-2018 IPR004513 Cell division protein FtsX GO:0016021 MIM_c09100 fb0288a85a45ae3ec003b12b6d782710 302 Pfam PF02687 FtsX-like permease family 206 298 7.1E-7 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MIM_c15990 fcfed103578aebb426fa0c5b59c9838f 955 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c15990 fcfed103578aebb426fa0c5b59c9838f 955 SUPERFAMILY SSF47323 673 945 1.05E-66 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c15990 fcfed103578aebb426fa0c5b59c9838f 955 SUPERFAMILY SSF52374 1 669 8.85E-132 T 12-10-2018 MIM_c15990 fcfed103578aebb426fa0c5b59c9838f 955 Gene3D G3DSA:3.90.740.10 191 415 3.3E-214 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MIM_c15990 fcfed103578aebb426fa0c5b59c9838f 955 Gene3D G3DSA:3.40.50.620 24 649 3.3E-214 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c15990 fcfed103578aebb426fa0c5b59c9838f 955 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 946 20.403 T 12-10-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 MIM_c15990 fcfed103578aebb426fa0c5b59c9838f 955 Pfam PF06827 Zinc finger found in FPG and IleRS 917 942 5.6E-6 T 12-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 MIM_c15990 fcfed103578aebb426fa0c5b59c9838f 955 Pfam PF08264 Anticodon-binding domain of tRNA 706 867 3.6E-23 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 MIM_c15990 fcfed103578aebb426fa0c5b59c9838f 955 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 661 7.6E-186 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c15990 fcfed103578aebb426fa0c5b59c9838f 955 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 582 591 5.7E-31 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MIM_c15990 fcfed103578aebb426fa0c5b59c9838f 955 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 5.7E-31 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MIM_c15990 fcfed103578aebb426fa0c5b59c9838f 955 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 408 423 5.7E-31 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MIM_c15990 fcfed103578aebb426fa0c5b59c9838f 955 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 539 552 5.7E-31 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MIM_c15990 fcfed103578aebb426fa0c5b59c9838f 955 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 233 256 5.7E-31 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MIM_c15990 fcfed103578aebb426fa0c5b59c9838f 955 Gene3D G3DSA:1.10.730.20 661 947 3.5E-85 T 12-10-2018 MIM_c15990 fcfed103578aebb426fa0c5b59c9838f 955 SUPERFAMILY SSF50677 200 410 5.02E-45 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MIM_c15990 fcfed103578aebb426fa0c5b59c9838f 955 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 14 870 1.5E-259 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MIM_c39010 c04510d0ddff8ebb40a0e98826223cbb 62 PIRSF PIRSF002211 1 62 2.0E-26 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c39010 c04510d0ddff8ebb40a0e98826223cbb 62 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 3 61 19.853 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c39010 c04510d0ddff8ebb40a0e98826223cbb 62 SUPERFAMILY SSF55129 5 61 6.8E-20 T 12-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily MIM_c39010 c04510d0ddff8ebb40a0e98826223cbb 62 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 7 61 4.2E-24 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c39010 c04510d0ddff8ebb40a0e98826223cbb 62 Gene3D G3DSA:3.30.1390.20 3 61 1.1E-23 T 12-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily MIM_c39010 c04510d0ddff8ebb40a0e98826223cbb 62 ProSitePatterns PS00634 Ribosomal protein L30 signature. 25 57 - T 12-10-2018 IPR018038 Ribosomal protein L30, conserved site MIM_c39010 c04510d0ddff8ebb40a0e98826223cbb 62 Pfam PF00327 Ribosomal protein L30p/L7e 7 57 2.7E-17 T 12-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain MIM_c27050 2d044514e064d9c8f52c14bcca9cf5f0 186 SUPERFAMILY SSF51278 79 183 3.01E-41 T 12-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c27050 2d044514e064d9c8f52c14bcca9cf5f0 186 Pfam PF00699 Urease beta subunit 81 177 1.6E-37 T 12-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c27050 2d044514e064d9c8f52c14bcca9cf5f0 186 Gene3D G3DSA:2.10.150.10 79 186 2.4E-41 T 12-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c27050 2d044514e064d9c8f52c14bcca9cf5f0 186 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 79 180 6.9E-37 T 12-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c09780 d533413af9eb2f2389b9976ffadcf193 320 Gene3D G3DSA:3.30.1490.20 114 179 5.4E-70 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MIM_c09780 d533413af9eb2f2389b9976ffadcf193 320 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 248 276 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MIM_c09780 d533413af9eb2f2389b9976ffadcf193 320 Pfam PF01820 D-ala D-ala ligase N-terminus 7 89 1.3E-18 T 12-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MIM_c09780 d533413af9eb2f2389b9976ffadcf193 320 SUPERFAMILY SSF56059 99 303 2.02E-57 T 12-10-2018 MIM_c09780 d533413af9eb2f2389b9976ffadcf193 320 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 66 77 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MIM_c09780 d533413af9eb2f2389b9976ffadcf193 320 Pfam PF07478 D-ala D-ala ligase C-terminus 107 302 3.0E-52 T 12-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MIM_c09780 d533413af9eb2f2389b9976ffadcf193 320 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 6 306 34.377 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MIM_c09780 d533413af9eb2f2389b9976ffadcf193 320 Gene3D G3DSA:3.30.470.20 88 301 5.4E-70 T 12-10-2018 MIM_c09780 d533413af9eb2f2389b9976ffadcf193 320 Gene3D G3DSA:3.40.50.20 1 87 2.2E-29 T 12-10-2018 MIM_c09780 d533413af9eb2f2389b9976ffadcf193 320 PIRSF PIRSF039102 4 55 6.5E-7 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MIM_c09780 d533413af9eb2f2389b9976ffadcf193 320 PIRSF PIRSF039102 44 313 6.5E-82 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MIM_c09780 d533413af9eb2f2389b9976ffadcf193 320 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 7 305 1.5E-94 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MIM_c09780 d533413af9eb2f2389b9976ffadcf193 320 SUPERFAMILY SSF52440 7 99 3.36E-29 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MIM_c12980 042ebd5f497f3fe3e1cd4a735d9e98e2 206 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 4 154 5.0E-37 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MIM_c12980 042ebd5f497f3fe3e1cd4a735d9e98e2 206 PIRSF PIRSF006755 1 202 3.3E-44 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MIM_c12980 042ebd5f497f3fe3e1cd4a735d9e98e2 206 SUPERFAMILY SSF52540 1 182 5.67E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c12980 042ebd5f497f3fe3e1cd4a735d9e98e2 206 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 197 24.506 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MIM_c12980 042ebd5f497f3fe3e1cd4a735d9e98e2 206 Pfam PF13500 AAA domain 2 179 1.3E-49 T 12-10-2018 MIM_c12980 042ebd5f497f3fe3e1cd4a735d9e98e2 206 Gene3D G3DSA:3.40.50.300 1 193 1.3E-53 T 12-10-2018 MIM_c29880 fe29167d81f0acef76a2d40688e6ebe8 270 Gene3D G3DSA:3.30.70.2970 62 185 4.3E-10 T 12-10-2018 MIM_c29880 fe29167d81f0acef76a2d40688e6ebe8 270 Gene3D G3DSA:3.30.110.170 53 261 4.3E-10 T 12-10-2018 MIM_c29880 fe29167d81f0acef76a2d40688e6ebe8 270 Pfam PF04402 Protein of unknown function (DUF541) 52 263 1.6E-23 T 12-10-2018 IPR007497 Protein of unknown function DUF541 MIM_c01210 7cdb596dc28007d4c72fcfac73f34603 348 Pfam PF00753 Metallo-beta-lactamase superfamily 114 247 2.8E-18 T 12-10-2018 IPR001279 Metallo-beta-lactamase MIM_c01210 7cdb596dc28007d4c72fcfac73f34603 348 SUPERFAMILY SSF56281 98 304 3.54E-41 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MIM_c01210 7cdb596dc28007d4c72fcfac73f34603 348 SMART SM00849 113 300 2.9E-25 T 12-10-2018 IPR001279 Metallo-beta-lactamase MIM_c01210 7cdb596dc28007d4c72fcfac73f34603 348 Gene3D G3DSA:3.60.15.10 90 343 1.3E-59 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MIM_c08160 d6ccd2a065207d8fadb22d414161be3c 339 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 39 312 1.6E-73 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 MIM_c08160 d6ccd2a065207d8fadb22d414161be3c 339 PIRSF PIRSF006470 6 336 4.4E-72 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 MIM_c08160 d6ccd2a065207d8fadb22d414161be3c 339 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 39 291 1.6E-69 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 MIM_c08160 d6ccd2a065207d8fadb22d414161be3c 339 Gene3D G3DSA:3.40.190.170 31 339 6.5E-107 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily MIM_c15740 87a4ce8a49813757d3b93b6a67b712e6 406 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 10 18 - T 12-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MIM_c15740 87a4ce8a49813757d3b93b6a67b712e6 406 Pfam PF00764 Arginosuccinate synthase 8 399 2.4E-150 T 12-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MIM_c15740 87a4ce8a49813757d3b93b6a67b712e6 406 SUPERFAMILY SSF52402 5 169 7.94E-47 T 12-10-2018 MIM_c15740 87a4ce8a49813757d3b93b6a67b712e6 406 Gene3D G3DSA:3.90.1260.10 181 406 1.3E-95 T 12-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MIM_c15740 87a4ce8a49813757d3b93b6a67b712e6 406 Hamap MF_00005 Argininosuccinate synthase [argG]. 4 405 51.369 T 12-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MIM_c15740 87a4ce8a49813757d3b93b6a67b712e6 406 TIGRFAM TIGR00032 argG: argininosuccinate synthase 6 399 3.1E-139 T 12-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MIM_c15740 87a4ce8a49813757d3b93b6a67b712e6 406 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 120 131 - T 12-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MIM_c15740 87a4ce8a49813757d3b93b6a67b712e6 406 SUPERFAMILY SSF69864 180 401 6.02E-90 T 12-10-2018 MIM_c15740 87a4ce8a49813757d3b93b6a67b712e6 406 Gene3D G3DSA:3.40.50.620 5 177 5.4E-67 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c05490 d7404afdfb1efe58d9431ce704af1c84 314 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 108 119 - T 12-10-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 MIM_c05490 d7404afdfb1efe58d9431ce704af1c84 314 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 31 303 3.4E-71 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 MIM_c05490 d7404afdfb1efe58d9431ce704af1c84 314 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 30 254 32.785 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 MIM_c05490 d7404afdfb1efe58d9431ce704af1c84 314 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 31 233 5.2E-29 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 MIM_c05490 d7404afdfb1efe58d9431ce704af1c84 314 Gene3D G3DSA:3.30.950.10 138 262 9.7E-36 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 MIM_c05490 d7404afdfb1efe58d9431ce704af1c84 314 PIRSF PIRSF005917 19 308 7.9E-93 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 MIM_c05490 d7404afdfb1efe58d9431ce704af1c84 314 Gene3D G3DSA:3.40.1010.10 16 137 2.1E-37 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 MIM_c05490 d7404afdfb1efe58d9431ce704af1c84 314 SUPERFAMILY SSF53790 29 252 5.1E-71 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 MIM_c40810 db4639a95e4f26552ed481c7222612a0 446 SUPERFAMILY SSF56024 54 240 9.68E-40 T 12-10-2018 MIM_c40810 db4639a95e4f26552ed481c7222612a0 446 Gene3D G3DSA:3.30.870.10 53 262 7.7E-36 T 12-10-2018 MIM_c40810 db4639a95e4f26552ed481c7222612a0 446 Pfam PF13091 PLD-like domain 317 444 7.6E-17 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MIM_c40810 db4639a95e4f26552ed481c7222612a0 446 Pfam PF13091 PLD-like domain 82 227 5.1E-14 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MIM_c40810 db4639a95e4f26552ed481c7222612a0 446 SUPERFAMILY SSF56024 283 444 1.1E-25 T 12-10-2018 MIM_c40810 db4639a95e4f26552ed481c7222612a0 446 Gene3D G3DSA:3.30.870.10 289 446 2.8E-33 T 12-10-2018 MIM_c40810 db4639a95e4f26552ed481c7222612a0 446 SMART SM00155 168 195 0.15 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MIM_c40810 db4639a95e4f26552ed481c7222612a0 446 SMART SM00155 408 435 4.7E-5 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MIM_c36740 2dc0452463df8d78bfe66551746187ee 309 Gene3D G3DSA:3.40.190.10 88 289 2.4E-48 T 12-10-2018 MIM_c36740 2dc0452463df8d78bfe66551746187ee 309 SUPERFAMILY SSF46785 1 80 6.82E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c36740 2dc0452463df8d78bfe66551746187ee 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.2E-23 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c36740 2dc0452463df8d78bfe66551746187ee 309 SUPERFAMILY SSF53850 87 297 2.96E-26 T 12-10-2018 MIM_c36740 2dc0452463df8d78bfe66551746187ee 309 Gene3D G3DSA:1.10.10.10 1 83 1.4E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c36740 2dc0452463df8d78bfe66551746187ee 309 Gene3D G3DSA:3.40.190.10 166 272 2.4E-48 T 12-10-2018 MIM_c36740 2dc0452463df8d78bfe66551746187ee 309 Pfam PF03466 LysR substrate binding domain 88 296 3.0E-30 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c36740 2dc0452463df8d78bfe66551746187ee 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.4E-11 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c36740 2dc0452463df8d78bfe66551746187ee 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.4E-11 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c36740 2dc0452463df8d78bfe66551746187ee 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.4E-11 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c07300 00ae5a6951be23fc8a22c54f89e77fe2 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 110 6.6E-27 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c07300 00ae5a6951be23fc8a22c54f89e77fe2 222 Gene3D G3DSA:1.10.3720.10 1 218 3.0E-58 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c07300 00ae5a6951be23fc8a22c54f89e77fe2 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 215 1.6E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c07300 00ae5a6951be23fc8a22c54f89e77fe2 222 SUPERFAMILY SSF161098 12 201 2.75E-47 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c01290 15f9020b353e3c615f2b4ac9b3e0ef8f 232 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 4.3E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c01290 15f9020b353e3c615f2b4ac9b3e0ef8f 232 Gene3D G3DSA:1.20.120.530 75 218 2.3E-16 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c01290 15f9020b353e3c615f2b4ac9b3e0ef8f 232 SUPERFAMILY SSF46785 7 78 8.76E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c01290 15f9020b353e3c615f2b4ac9b3e0ef8f 232 SUPERFAMILY SSF48008 86 217 2.2E-15 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c01290 15f9020b353e3c615f2b4ac9b3e0ef8f 232 Pfam PF07729 FCD domain 86 212 3.1E-15 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c01290 15f9020b353e3c615f2b4ac9b3e0ef8f 232 SMART SM00345 16 74 3.5E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c01290 15f9020b353e3c615f2b4ac9b3e0ef8f 232 Gene3D G3DSA:1.10.10.10 8 74 2.1E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c01290 15f9020b353e3c615f2b4ac9b3e0ef8f 232 SMART SM00895 84 213 6.5E-7 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c16350 ad5f3c6935b561d0941335dc05f61290 380 SUPERFAMILY SSF89796 12 376 3.27E-128 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c16350 ad5f3c6935b561d0941335dc05f61290 380 Pfam PF02515 CoA-transferase family III 13 374 8.8E-123 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 MIM_c16350 ad5f3c6935b561d0941335dc05f61290 380 Gene3D G3DSA:3.40.50.10540 13 357 1.1E-128 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c16350 ad5f3c6935b561d0941335dc05f61290 380 Gene3D G3DSA:3.30.1540.10 233 324 1.1E-128 T 12-10-2018 MIM_c12140 41487c399a96f733e9f75f85fe56aea2 296 SUPERFAMILY SSF53850 1 264 4.98E-57 T 12-10-2018 MIM_c12140 41487c399a96f733e9f75f85fe56aea2 296 Gene3D G3DSA:3.40.190.10 24 266 5.9E-88 T 12-10-2018 MIM_c12140 41487c399a96f733e9f75f85fe56aea2 296 Gene3D G3DSA:3.40.190.10 125 220 5.9E-88 T 12-10-2018 MIM_c12140 41487c399a96f733e9f75f85fe56aea2 296 SMART SM00062 33 263 5.0E-50 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c12140 41487c399a96f733e9f75f85fe56aea2 296 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 261 2.1E-47 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c38150 02c0f121aa57eb80ed710f8723f42a6b 515 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 169 1.3E-36 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MIM_c38150 02c0f121aa57eb80ed710f8723f42a6b 515 SUPERFAMILY SSF52467 176 327 1.43E-7 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MIM_c38150 02c0f121aa57eb80ed710f8723f42a6b 515 Gene3D G3DSA:3.40.50.1220 178 330 1.4E-7 T 12-10-2018 MIM_c38150 02c0f121aa57eb80ed710f8723f42a6b 515 SUPERFAMILY SSF52518 1 176 1.28E-39 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c38150 02c0f121aa57eb80ed710f8723f42a6b 515 Gene3D G3DSA:3.40.50.970 1 176 1.1E-41 T 12-10-2018 MIM_c38150 02c0f121aa57eb80ed710f8723f42a6b 515 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 383 512 6.0E-26 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MIM_c38150 02c0f121aa57eb80ed710f8723f42a6b 515 Gene3D G3DSA:3.40.50.970 334 515 5.9E-43 T 12-10-2018 MIM_c38150 02c0f121aa57eb80ed710f8723f42a6b 515 SUPERFAMILY SSF52518 338 515 1.47E-39 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c21520 a13fed4b29d3d946d8974e335df8dc78 842 Gene3D G3DSA:2.40.170.20 296 841 1.4E-68 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MIM_c21520 a13fed4b29d3d946d8974e335df8dc78 842 Pfam PF07715 TonB-dependent Receptor Plug Domain 165 267 2.0E-18 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain MIM_c21520 a13fed4b29d3d946d8974e335df8dc78 842 SMART SM00965 77 128 2.7E-6 T 12-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MIM_c21520 a13fed4b29d3d946d8974e335df8dc78 842 Pfam PF00593 TonB dependent receptor 375 837 4.8E-45 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MIM_c21520 a13fed4b29d3d946d8974e335df8dc78 842 Gene3D G3DSA:3.55.50.30 55 126 3.2E-23 T 12-10-2018 MIM_c21520 a13fed4b29d3d946d8974e335df8dc78 842 SUPERFAMILY SSF56935 154 842 3.0E-93 T 12-10-2018 MIM_c21520 a13fed4b29d3d946d8974e335df8dc78 842 Gene3D G3DSA:2.170.130.10 162 275 7.6E-19 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MIM_c21520 a13fed4b29d3d946d8974e335df8dc78 842 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 171 822 6.7E-97 T 12-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 MIM_c30760 9171fa7e6c1456c97f9aeb12e4319ea2 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 323 1.4E-80 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c30760 9171fa7e6c1456c97f9aeb12e4319ea2 329 Gene3D G3DSA:3.40.190.150 32 318 4.7E-110 T 12-10-2018 MIM_c30760 9171fa7e6c1456c97f9aeb12e4319ea2 329 SUPERFAMILY SSF53850 114 286 5.43E-9 T 12-10-2018 MIM_c30760 9171fa7e6c1456c97f9aeb12e4319ea2 329 Gene3D G3DSA:3.40.190.10 130 253 4.7E-110 T 12-10-2018 MIM_c30760 9171fa7e6c1456c97f9aeb12e4319ea2 329 PIRSF PIRSF017082 1 328 5.2E-78 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c19410 f356711fa20059e8d8e806b89d7e8be3 789 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 33 789 4.1E-245 T 12-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 MIM_c19410 f356711fa20059e8d8e806b89d7e8be3 789 Gene3D G3DSA:3.10.20.310 357 433 2.5E-25 T 12-10-2018 MIM_c19410 f356711fa20059e8d8e806b89d7e8be3 789 Gene3D G3DSA:3.10.20.310 274 355 1.9E-14 T 12-10-2018 MIM_c19410 f356711fa20059e8d8e806b89d7e8be3 789 PIRSF PIRSF006076 1 789 5.3E-235 T 12-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 MIM_c19410 f356711fa20059e8d8e806b89d7e8be3 789 Pfam PF01103 Surface antigen 457 789 6.2E-72 T 12-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 MIM_c19410 f356711fa20059e8d8e806b89d7e8be3 789 Gene3D G3DSA:3.10.20.310 101 182 1.0E-14 T 12-10-2018 MIM_c19410 f356711fa20059e8d8e806b89d7e8be3 789 Pfam PF07244 Surface antigen variable number repeat 275 353 5.4E-10 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 MIM_c19410 f356711fa20059e8d8e806b89d7e8be3 789 Pfam PF07244 Surface antigen variable number repeat 356 430 1.3E-14 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 MIM_c19410 f356711fa20059e8d8e806b89d7e8be3 789 Pfam PF07244 Surface antigen variable number repeat 185 272 1.3E-15 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 MIM_c19410 f356711fa20059e8d8e806b89d7e8be3 789 Pfam PF07244 Surface antigen variable number repeat 101 180 9.8E-9 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 MIM_c19410 f356711fa20059e8d8e806b89d7e8be3 789 Gene3D G3DSA:3.10.20.310 29 100 2.1E-15 T 12-10-2018 MIM_c19410 f356711fa20059e8d8e806b89d7e8be3 789 Gene3D G3DSA:2.40.160.50 434 789 9.4E-96 T 12-10-2018 MIM_c19410 f356711fa20059e8d8e806b89d7e8be3 789 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 17 789 24.201 T 12-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 MIM_c19410 f356711fa20059e8d8e806b89d7e8be3 789 Gene3D G3DSA:3.10.20.310 184 273 1.1E-24 T 12-10-2018 MIM_c19830 3d881d41779a9e409e14736356671b5b 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 51 2.0E-12 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MIM_c19830 3d881d41779a9e409e14736356671b5b 338 Gene3D G3DSA:3.40.50.2300 169 297 1.9E-32 T 12-10-2018 MIM_c19830 3d881d41779a9e409e14736356671b5b 338 SMART SM00354 3 74 1.2E-17 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MIM_c19830 3d881d41779a9e409e14736356671b5b 338 Gene3D G3DSA:3.40.50.2300 79 321 1.9E-32 T 12-10-2018 MIM_c19830 3d881d41779a9e409e14736356671b5b 338 SUPERFAMILY SSF47413 2 61 2.88E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c19830 3d881d41779a9e409e14736356671b5b 338 Gene3D G3DSA:1.10.260.40 1 62 3.2E-19 T 12-10-2018 MIM_c19830 3d881d41779a9e409e14736356671b5b 338 SUPERFAMILY SSF53822 77 330 1.03E-26 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c19830 3d881d41779a9e409e14736356671b5b 338 Pfam PF13377 Periplasmic binding protein-like domain 200 336 3.2E-14 T 12-10-2018 MIM_c35360 2aa6677f54f599c252cbd21ec19a79fd 315 SMART SM00382 71 252 3.1E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c35360 2aa6677f54f599c252cbd21ec19a79fd 315 Pfam PF00005 ABC transporter 62 201 3.9E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c35360 2aa6677f54f599c252cbd21ec19a79fd 315 Gene3D G3DSA:3.40.50.300 40 277 6.2E-58 T 12-10-2018 MIM_c35360 2aa6677f54f599c252cbd21ec19a79fd 315 ProSitePatterns PS00211 ABC transporters family signature. 174 188 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c35360 2aa6677f54f599c252cbd21ec19a79fd 315 SUPERFAMILY SSF52540 45 277 3.5E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c08250 2dc9bb590a835dc7b073f96db5625a52 255 SUPERFAMILY SSF52096 9 255 2.35E-55 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c08250 2dc9bb590a835dc7b073f96db5625a52 255 Gene3D G3DSA:1.10.12.10 210 255 6.1E-6 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MIM_c08250 2dc9bb590a835dc7b073f96db5625a52 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 254 1.1E-32 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c08250 2dc9bb590a835dc7b073f96db5625a52 255 Gene3D G3DSA:3.90.226.10 10 209 4.8E-47 T 12-10-2018 MIM_c08250 2dc9bb590a835dc7b073f96db5625a52 255 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 MIM_c15490 1bc585578181c93539adc53cce14e655 433 Pfam PF00009 Elongation factor Tu GTP binding domain 10 202 6.0E-37 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c15490 1bc585578181c93539adc53cce14e655 433 PRINTS PR00315 GTP-binding elongation factor signature 152 161 1.8E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c15490 1bc585578181c93539adc53cce14e655 433 PRINTS PR00315 GTP-binding elongation factor signature 11 24 1.8E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c15490 1bc585578181c93539adc53cce14e655 433 PRINTS PR00315 GTP-binding elongation factor signature 91 101 1.8E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c15490 1bc585578181c93539adc53cce14e655 433 PRINTS PR00315 GTP-binding elongation factor signature 107 118 1.8E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c15490 1bc585578181c93539adc53cce14e655 433 PRINTS PR00315 GTP-binding elongation factor signature 71 79 1.8E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c15490 1bc585578181c93539adc53cce14e655 433 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 64 79 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site MIM_c15490 1bc585578181c93539adc53cce14e655 433 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 10 429 2.0E-158 T 12-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MIM_c15490 1bc585578181c93539adc53cce14e655 433 SUPERFAMILY SSF52540 1 224 3.3E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c15490 1bc585578181c93539adc53cce14e655 433 SUPERFAMILY SSF50465 328 430 4.03E-29 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal MIM_c15490 1bc585578181c93539adc53cce14e655 433 Gene3D G3DSA:3.40.50.300 1 228 6.7E-63 T 12-10-2018 MIM_c15490 1bc585578181c93539adc53cce14e655 433 Gene3D G3DSA:2.40.30.10 233 323 3.4E-18 T 12-10-2018 MIM_c15490 1bc585578181c93539adc53cce14e655 433 SUPERFAMILY SSF50447 233 322 5.96E-16 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MIM_c15490 1bc585578181c93539adc53cce14e655 433 Gene3D G3DSA:2.40.30.10 326 430 9.2E-33 T 12-10-2018 MIM_c40050 cc89fc25bc45c95ad311acbb283cd4bc 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 8.5E-15 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MIM_c40050 cc89fc25bc45c95ad311acbb283cd4bc 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.342 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MIM_c40050 cc89fc25bc45c95ad311acbb283cd4bc 396 SUPERFAMILY SSF50465 304 396 1.7E-35 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal MIM_c40050 cc89fc25bc45c95ad311acbb283cd4bc 396 Gene3D G3DSA:2.40.30.10 340 395 1.8E-28 T 12-10-2018 MIM_c40050 cc89fc25bc45c95ad311acbb283cd4bc 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.9E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c40050 cc89fc25bc45c95ad311acbb283cd4bc 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.9E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c40050 cc89fc25bc45c95ad311acbb283cd4bc 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.9E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c40050 cc89fc25bc45c95ad311acbb283cd4bc 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.9E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c40050 cc89fc25bc45c95ad311acbb283cd4bc 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.9E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c40050 cc89fc25bc45c95ad311acbb283cd4bc 396 Gene3D G3DSA:2.40.30.10 208 336 8.4E-52 T 12-10-2018 MIM_c40050 cc89fc25bc45c95ad311acbb283cd4bc 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 1.0E-33 T 12-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal MIM_c40050 cc89fc25bc45c95ad311acbb283cd4bc 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 3.3E-58 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c40050 cc89fc25bc45c95ad311acbb283cd4bc 396 SUPERFAMILY SSF50447 207 303 7.86E-31 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MIM_c40050 cc89fc25bc45c95ad311acbb283cd4bc 396 Gene3D G3DSA:3.40.50.300 1 205 7.2E-69 T 12-10-2018 MIM_c40050 cc89fc25bc45c95ad311acbb283cd4bc 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site MIM_c40050 cc89fc25bc45c95ad311acbb283cd4bc 396 SUPERFAMILY SSF52540 5 221 2.13E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c40050 cc89fc25bc45c95ad311acbb283cd4bc 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 1.9E-17 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MIM_c40050 cc89fc25bc45c95ad311acbb283cd4bc 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 395 4.1E-228 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MIM_c40710 cc89fc25bc45c95ad311acbb283cd4bc 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 8.5E-15 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MIM_c40710 cc89fc25bc45c95ad311acbb283cd4bc 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.342 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MIM_c40710 cc89fc25bc45c95ad311acbb283cd4bc 396 SUPERFAMILY SSF50465 304 396 1.7E-35 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal MIM_c40710 cc89fc25bc45c95ad311acbb283cd4bc 396 Gene3D G3DSA:2.40.30.10 340 395 1.8E-28 T 12-10-2018 MIM_c40710 cc89fc25bc45c95ad311acbb283cd4bc 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.9E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c40710 cc89fc25bc45c95ad311acbb283cd4bc 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.9E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c40710 cc89fc25bc45c95ad311acbb283cd4bc 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.9E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c40710 cc89fc25bc45c95ad311acbb283cd4bc 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.9E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c40710 cc89fc25bc45c95ad311acbb283cd4bc 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.9E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c40710 cc89fc25bc45c95ad311acbb283cd4bc 396 Gene3D G3DSA:2.40.30.10 208 336 8.4E-52 T 12-10-2018 MIM_c40710 cc89fc25bc45c95ad311acbb283cd4bc 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 1.0E-33 T 12-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal MIM_c40710 cc89fc25bc45c95ad311acbb283cd4bc 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 3.3E-58 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c40710 cc89fc25bc45c95ad311acbb283cd4bc 396 SUPERFAMILY SSF50447 207 303 7.86E-31 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MIM_c40710 cc89fc25bc45c95ad311acbb283cd4bc 396 Gene3D G3DSA:3.40.50.300 1 205 7.2E-69 T 12-10-2018 MIM_c40710 cc89fc25bc45c95ad311acbb283cd4bc 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site MIM_c40710 cc89fc25bc45c95ad311acbb283cd4bc 396 SUPERFAMILY SSF52540 5 221 2.13E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c40710 cc89fc25bc45c95ad311acbb283cd4bc 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 1.9E-17 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MIM_c40710 cc89fc25bc45c95ad311acbb283cd4bc 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 395 4.1E-228 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MIM_c10770 b13097f0042e16473668fb6e20907788 128 Pfam PF01844 HNH endonuclease 69 115 2.7E-8 T 12-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 MIM_c10770 b13097f0042e16473668fb6e20907788 128 SMART SM00507 56 110 1.9E-7 T 12-10-2018 IPR003615 HNH nuclease MIM_c10770 b13097f0042e16473668fb6e20907788 128 Gene3D G3DSA:3.30.40.60 29 128 9.9E-6 T 12-10-2018 MIM_c05920 337032110b8a0d7c4ca3ecac90623110 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 298 2.1E-30 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c05920 337032110b8a0d7c4ca3ecac90623110 300 SUPERFAMILY SSF161098 92 282 1.11E-31 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c05920 337032110b8a0d7c4ca3ecac90623110 300 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 22 74 3.2E-12 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MIM_c05920 337032110b8a0d7c4ca3ecac90623110 300 Gene3D G3DSA:1.10.3720.10 88 294 4.4E-25 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c18170 dceb2c3646a5ab67b82a4d55c405d9c5 240 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 189 201 9.1E-12 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MIM_c18170 dceb2c3646a5ab67b82a4d55c405d9c5 240 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 150 160 9.1E-12 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MIM_c18170 dceb2c3646a5ab67b82a4d55c405d9c5 240 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 161 172 9.1E-12 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MIM_c18170 dceb2c3646a5ab67b82a4d55c405d9c5 240 SUPERFAMILY SSF46785 4 70 1.81E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c18170 dceb2c3646a5ab67b82a4d55c405d9c5 240 Gene3D G3DSA:1.10.10.10 3 71 4.6E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c18170 dceb2c3646a5ab67b82a4d55c405d9c5 240 Gene3D G3DSA:2.10.109.10 119 239 2.7E-42 T 12-10-2018 MIM_c18170 dceb2c3646a5ab67b82a4d55c405d9c5 240 Pfam PF00717 Peptidase S24-like 153 220 2.0E-14 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MIM_c18170 dceb2c3646a5ab67b82a4d55c405d9c5 240 Hamap MF_00015 LexA repressor [lexA]. 4 237 31.663 T 12-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 MIM_c18170 dceb2c3646a5ab67b82a4d55c405d9c5 240 TIGRFAM TIGR00498 lexA: repressor LexA 4 236 1.0E-70 T 12-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 MIM_c18170 dceb2c3646a5ab67b82a4d55c405d9c5 240 SUPERFAMILY SSF51306 114 235 4.19E-35 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily MIM_c18170 dceb2c3646a5ab67b82a4d55c405d9c5 240 Pfam PF01726 LexA DNA binding domain 4 66 4.1E-27 T 12-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 MIM_c15140 af97280e5330c566b75edbd912801f7a 253 Gene3D G3DSA:1.20.58.220 1 114 2.7E-34 T 12-10-2018 IPR038078 PhoU-like domain superfamily MIM_c15140 af97280e5330c566b75edbd912801f7a 253 Gene3D G3DSA:1.20.58.220 115 233 4.1E-35 T 12-10-2018 IPR038078 PhoU-like domain superfamily MIM_c15140 af97280e5330c566b75edbd912801f7a 253 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 8 217 4.4E-66 T 12-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 MIM_c15140 af97280e5330c566b75edbd912801f7a 253 Pfam PF01895 PhoU domain 127 209 1.2E-17 T 12-10-2018 IPR026022 PhoU domain MIM_c15140 af97280e5330c566b75edbd912801f7a 253 Pfam PF01895 PhoU domain 21 107 6.6E-19 T 12-10-2018 IPR026022 PhoU domain MIM_c15140 af97280e5330c566b75edbd912801f7a 253 SUPERFAMILY SSF109755 8 227 1.78E-67 T 12-10-2018 MIM_c15140 af97280e5330c566b75edbd912801f7a 253 PIRSF PIRSF003107 2 223 3.4E-61 T 12-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 MIM_c10720 0cd0476f3b21bba48c5efcdf741cdee8 232 Pfam PF00149 Calcineurin-like phosphoesterase 23 167 2.8E-10 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MIM_c10720 0cd0476f3b21bba48c5efcdf741cdee8 232 Gene3D G3DSA:3.60.21.10 7 228 2.3E-44 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like MIM_c10720 0cd0476f3b21bba48c5efcdf741cdee8 232 SUPERFAMILY SSF56300 15 227 1.12E-35 T 12-10-2018 MIM_c33200 a1fbf975fd88407e2a71426e9da0c010 244 SUPERFAMILY SSF89562 69 210 1.19E-28 T 12-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily MIM_c33200 a1fbf975fd88407e2a71426e9da0c010 244 Gene3D G3DSA:3.50.30.100 9 222 2.6E-44 T 12-10-2018 MIM_c33200 a1fbf975fd88407e2a71426e9da0c010 244 Pfam PF03737 Aldolase/RraA 41 198 3.6E-26 T 12-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MIM_c06160 98258621409997bb1ead607ffc38da15 193 Hamap MF_00836 Ribose 1,5-bisphosphate phosphokinase PhnN [phnN]. 2 185 30.779 T 12-10-2018 IPR012699 Ribose 1,5-bisphosphate phosphokinase PhnN GO:0006015|GO:0033863 KEGG: 00030+2.7.4.23|MetaCyc: PWY-7805|MetaCyc: PWY-7807 MIM_c06160 98258621409997bb1ead607ffc38da15 193 SMART SM00072 2 188 3.8E-5 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit MIM_c06160 98258621409997bb1ead607ffc38da15 193 Pfam PF00625 Guanylate kinase 5 185 5.4E-5 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit MIM_c06160 98258621409997bb1ead607ffc38da15 193 TIGRFAM TIGR02322 phosphon_PhnN: phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN 3 186 8.7E-60 T 12-10-2018 IPR012699 Ribose 1,5-bisphosphate phosphokinase PhnN GO:0006015|GO:0033863 KEGG: 00030+2.7.4.23|MetaCyc: PWY-7805|MetaCyc: PWY-7807 MIM_c06160 98258621409997bb1ead607ffc38da15 193 Gene3D G3DSA:3.40.50.300 2 188 2.5E-18 T 12-10-2018 MIM_c06160 98258621409997bb1ead607ffc38da15 193 SUPERFAMILY SSF52540 3 188 2.75E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c03240 59c4953445a91ea754f10d0db19a1b88 152 Hamap MF_00598 Protein Smg [smg]. 1 152 25.898 T 12-10-2018 IPR007456 Smg MIM_c03240 59c4953445a91ea754f10d0db19a1b88 152 Pfam PF04361 Protein of unknown function (DUF494) 1 152 3.5E-53 T 12-10-2018 IPR007456 Smg MIM_c11900 622b5568afade1db111fcab5254891b6 259 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 49 62 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site MIM_c11900 622b5568afade1db111fcab5254891b6 259 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 27 253 4.3E-58 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c11900 622b5568afade1db111fcab5254891b6 259 SMART SM00062 26 255 1.3E-62 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c11900 622b5568afade1db111fcab5254891b6 259 Gene3D G3DSA:3.40.190.10 28 251 2.1E-74 T 12-10-2018 MIM_c11900 622b5568afade1db111fcab5254891b6 259 SUPERFAMILY SSF53850 6 255 1.3E-60 T 12-10-2018 MIM_c11900 622b5568afade1db111fcab5254891b6 259 Gene3D G3DSA:3.40.190.10 112 212 2.1E-74 T 12-10-2018 MIM_c23890 8a2f41dd87685d3b13b467fbe502bdba 409 SUPERFAMILY SSF53901 213 408 2.11E-68 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c23890 8a2f41dd87685d3b13b467fbe502bdba 409 SUPERFAMILY SSF53901 2 251 1.61E-81 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c23890 8a2f41dd87685d3b13b467fbe502bdba 409 SMART SM00825 Beta-ketoacyl synthase 5 409 5.4E-15 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MIM_c23890 8a2f41dd87685d3b13b467fbe502bdba 409 PIRSF PIRSF000447 1 409 1.2E-183 T 12-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 MIM_c23890 8a2f41dd87685d3b13b467fbe502bdba 409 Gene3D G3DSA:3.40.47.10 1 255 7.6E-98 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c23890 8a2f41dd87685d3b13b467fbe502bdba 409 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 246 2.0E-62 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MIM_c23890 8a2f41dd87685d3b13b467fbe502bdba 409 Gene3D G3DSA:3.40.47.10 256 398 5.8E-51 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c23890 8a2f41dd87685d3b13b467fbe502bdba 409 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 154 170 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site MIM_c23890 8a2f41dd87685d3b13b467fbe502bdba 409 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 366 2.0E-33 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MIM_c23890 8a2f41dd87685d3b13b467fbe502bdba 409 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 3 407 2.9E-199 T 12-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 MIM_c32330 5f35ee03ad7da3fe2e96249499ffe2be 443 Gene3D G3DSA:1.25.40.10 39 148 9.4E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MIM_c32330 5f35ee03ad7da3fe2e96249499ffe2be 443 SUPERFAMILY SSF48452 67 153 6.03E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MIM_c32330 5f35ee03ad7da3fe2e96249499ffe2be 443 Pfam PF04575 Protein of unknown function (DUF560) 155 443 1.9E-77 T 12-10-2018 IPR007655 Protein of unknown function DUF560 MIM_c34810 3f8f6d17c252849315594f2d4d2792cb 799 Pfam PF05954 Phage late control gene D protein (GPD) 30 330 8.5E-98 T 12-10-2018 MIM_c34810 3f8f6d17c252849315594f2d4d2792cb 799 SUPERFAMILY SSF69255 367 454 1.28E-31 T 12-10-2018 MIM_c34810 3f8f6d17c252849315594f2d4d2792cb 799 SUPERFAMILY SSF69279 191 365 8.33E-45 T 12-10-2018 MIM_c34810 3f8f6d17c252849315594f2d4d2792cb 799 Gene3D G3DSA:3.30.1920.30 227 289 6.9E-117 T 12-10-2018 MIM_c34810 3f8f6d17c252849315594f2d4d2792cb 799 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 20 524 3.0E-180 T 12-10-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset MIM_c34810 3f8f6d17c252849315594f2d4d2792cb 799 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 25 505 1.2E-146 T 12-10-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein MIM_c34810 3f8f6d17c252849315594f2d4d2792cb 799 Gene3D G3DSA:2.40.50.230 357 459 6.8E-42 T 12-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily MIM_c34810 3f8f6d17c252849315594f2d4d2792cb 799 SUPERFAMILY SSF69349 445 602 2.2E-22 T 12-10-2018 MIM_c34810 3f8f6d17c252849315594f2d4d2792cb 799 SUPERFAMILY SSF69279 19 187 4.25E-55 T 12-10-2018 MIM_c34810 3f8f6d17c252849315594f2d4d2792cb 799 Gene3D G3DSA:3.55.50.10 101 191 6.9E-117 T 12-10-2018 MIM_c34810 3f8f6d17c252849315594f2d4d2792cb 799 Gene3D G3DSA:2.30.110.50 16 333 6.9E-117 T 12-10-2018 MIM_c06300 0f10678f673ad4e24d93b18edcfaa1d9 260 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 254 1.3E-41 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c06300 0f10678f673ad4e24d93b18edcfaa1d9 260 Gene3D G3DSA:3.40.190.10 120 211 1.2E-75 T 12-10-2018 MIM_c06300 0f10678f673ad4e24d93b18edcfaa1d9 260 SUPERFAMILY SSF53850 1 257 7.12E-57 T 12-10-2018 MIM_c06300 0f10678f673ad4e24d93b18edcfaa1d9 260 SMART SM00062 34 257 1.7E-41 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c06300 0f10678f673ad4e24d93b18edcfaa1d9 260 Gene3D G3DSA:3.40.190.10 26 244 1.2E-75 T 12-10-2018 MIM_c41070 7c6430ff4343d011927601cfbb595ff5 316 Pfam PF03466 LysR substrate binding domain 90 296 5.8E-34 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c41070 7c6430ff4343d011927601cfbb595ff5 316 Gene3D G3DSA:3.40.190.290 93 301 4.2E-35 T 12-10-2018 MIM_c41070 7c6430ff4343d011927601cfbb595ff5 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 1.1E-13 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c41070 7c6430ff4343d011927601cfbb595ff5 316 SUPERFAMILY SSF53850 90 299 5.68E-42 T 12-10-2018 MIM_c41070 7c6430ff4343d011927601cfbb595ff5 316 SUPERFAMILY SSF46785 4 113 6.8E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c41070 7c6430ff4343d011927601cfbb595ff5 316 Gene3D G3DSA:1.10.10.10 5 92 3.3E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c12770 d7b2279128e616705fe91a23af1edd03 382 Pfam PF13378 Enolase C-terminal domain-like 153 362 3.8E-60 T 12-10-2018 IPR029065 Enolase C-terminal domain-like MIM_c12770 d7b2279128e616705fe91a23af1edd03 382 SUPERFAMILY SSF51604 115 367 1.02E-69 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MIM_c12770 d7b2279128e616705fe91a23af1edd03 382 SUPERFAMILY SSF54826 4 128 8.76E-30 T 12-10-2018 MIM_c12770 d7b2279128e616705fe91a23af1edd03 382 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 9 127 6.0E-23 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain MIM_c12770 d7b2279128e616705fe91a23af1edd03 382 Gene3D G3DSA:3.20.20.120 121 360 1.0E-104 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MIM_c12770 d7b2279128e616705fe91a23af1edd03 382 Gene3D G3DSA:3.30.390.10 7 365 1.0E-104 T 12-10-2018 IPR029017 Enolase-like, N-terminal MIM_c12770 d7b2279128e616705fe91a23af1edd03 382 SMART SM00922 149 247 5.6E-27 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MIM_c26640 b5cf0be8bddeb1b324f1efaea3d75779 266 Pfam PF01863 Protein of unknown function DUF45 42 255 1.4E-54 T 12-10-2018 IPR002725 Protein of unknown function DUF45 MIM_c26640 b5cf0be8bddeb1b324f1efaea3d75779 266 Gene3D G3DSA:3.30.2010.10 172 258 1.3E-18 T 12-10-2018 MIM_c06750 1aa5b355502e1d222b1f94cd4a123d4e 435 SUPERFAMILY SSF56601 1 328 7.47E-80 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MIM_c06750 1aa5b355502e1d222b1f94cd4a123d4e 435 SUPERFAMILY SSF69189 328 420 3.14E-19 T 12-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MIM_c06750 1aa5b355502e1d222b1f94cd4a123d4e 435 Gene3D G3DSA:3.40.710.10 68 327 1.1E-90 T 12-10-2018 MIM_c06750 1aa5b355502e1d222b1f94cd4a123d4e 435 Gene3D G3DSA:2.60.410.10 328 418 1.2E-21 T 12-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MIM_c06750 1aa5b355502e1d222b1f94cd4a123d4e 435 SMART SM00936 328 418 8.4E-24 T 12-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MIM_c06750 1aa5b355502e1d222b1f94cd4a123d4e 435 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 168 185 8.9E-16 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MIM_c06750 1aa5b355502e1d222b1f94cd4a123d4e 435 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 195 208 8.9E-16 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MIM_c06750 1aa5b355502e1d222b1f94cd4a123d4e 435 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 115 126 8.9E-16 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MIM_c06750 1aa5b355502e1d222b1f94cd4a123d4e 435 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 328 417 2.3E-15 T 12-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MIM_c06750 1aa5b355502e1d222b1f94cd4a123d4e 435 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 84 308 2.7E-78 T 12-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 MIM_c10390 b2185a7ed07f78cb8205a625bac578ee 248 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 248 90.162 T 12-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 MIM_c10390 b2185a7ed07f78cb8205a625bac578ee 248 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 39 225 1.1E-48 T 12-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 MIM_c10390 b2185a7ed07f78cb8205a625bac578ee 248 SUPERFAMILY SSF55729 3 233 2.75E-84 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c10390 b2185a7ed07f78cb8205a625bac578ee 248 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 36 213 1.0E-69 T 12-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 MIM_c10390 b2185a7ed07f78cb8205a625bac578ee 248 Gene3D G3DSA:2.30.210.20 5 61 3.6E-23 T 12-10-2018 MIM_c10390 b2185a7ed07f78cb8205a625bac578ee 248 Gene3D G3DSA:3.40.630.70 62 241 1.2E-61 T 12-10-2018 MIM_c00910 ced2af49315e620e6a865b749daf1fd3 400 SUPERFAMILY SSF103473 12 392 5.75E-55 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c00910 ced2af49315e620e6a865b749daf1fd3 400 Gene3D G3DSA:1.20.1250.20 7 385 4.9E-45 T 12-10-2018 MIM_c00910 ced2af49315e620e6a865b749daf1fd3 400 Pfam PF07690 Major Facilitator Superfamily 19 338 2.1E-33 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c19490 eb1a547c9c1e35e33066b0fe45f77e7e 257 SUPERFAMILY SSF75217 108 255 3.4E-40 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases MIM_c19490 eb1a547c9c1e35e33066b0fe45f77e7e 257 Pfam PF00588 SpoU rRNA Methylase family 111 248 6.9E-32 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MIM_c19490 eb1a547c9c1e35e33066b0fe45f77e7e 257 Gene3D G3DSA:3.40.1280.10 104 257 1.9E-42 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MIM_c19490 eb1a547c9c1e35e33066b0fe45f77e7e 257 Gene3D G3DSA:3.30.1330.30 9 100 5.7E-9 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like MIM_c19490 eb1a547c9c1e35e33066b0fe45f77e7e 257 SMART SM00967 28 102 0.0013 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MIM_c19490 eb1a547c9c1e35e33066b0fe45f77e7e 257 SUPERFAMILY SSF55315 3 99 1.53E-11 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like MIM_c38840 3947e5c1c7aca43faad14fe64fb58a45 541 ProSitePatterns PS00455 Putative AMP-binding domain signature. 186 197 - T 12-10-2018 IPR020845 AMP-binding, conserved site MIM_c38840 3947e5c1c7aca43faad14fe64fb58a45 541 Gene3D G3DSA:3.30.300.310 439 540 1.3E-31 T 12-10-2018 MIM_c38840 3947e5c1c7aca43faad14fe64fb58a45 541 Pfam PF13193 AMP-binding enzyme C-terminal domain 452 526 9.1E-19 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MIM_c38840 3947e5c1c7aca43faad14fe64fb58a45 541 SUPERFAMILY SSF56801 12 535 5.76E-140 T 12-10-2018 MIM_c38840 3947e5c1c7aca43faad14fe64fb58a45 541 Gene3D G3DSA:3.40.50.12780 8 438 2.8E-105 T 12-10-2018 MIM_c38840 3947e5c1c7aca43faad14fe64fb58a45 541 Pfam PF00501 AMP-binding enzyme 27 443 1.4E-90 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MIM_c40430 171ca46abc0514d23007f74eccc03519 208 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 42 201 1.8E-11 T 12-10-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like MIM_c40430 171ca46abc0514d23007f74eccc03519 208 SUPERFAMILY SSF89392 31 201 1.33E-17 T 12-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX MIM_c40430 171ca46abc0514d23007f74eccc03519 208 Gene3D G3DSA:2.50.20.10 29 202 7.0E-26 T 12-10-2018 MIM_c32670 65f6ca93c4fb5b7d257cf563babb337f 598 SMART SM00382 374 572 1.2E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c32670 65f6ca93c4fb5b7d257cf563babb337f 598 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 574 594 5.9E-7 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal MIM_c32670 65f6ca93c4fb5b7d257cf563babb337f 598 Pfam PF02653 Branched-chain amino acid transport system / permease component 32 300 3.2E-27 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c32670 65f6ca93c4fb5b7d257cf563babb337f 598 Gene3D G3DSA:3.40.50.300 344 595 3.7E-56 T 12-10-2018 MIM_c32670 65f6ca93c4fb5b7d257cf563babb337f 598 Pfam PF00005 ABC transporter 365 523 4.2E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c32670 65f6ca93c4fb5b7d257cf563babb337f 598 SUPERFAMILY SSF52540 349 593 2.57E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c11120 a1e22e76b34cb437f6e341c81aaa7db0 362 SUPERFAMILY SSF46689 89 136 1.92E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c11120 a1e22e76b34cb437f6e341c81aaa7db0 362 Pfam PF12833 Helix-turn-helix domain 110 188 3.2E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c11120 a1e22e76b34cb437f6e341c81aaa7db0 362 Pfam PF02805 Metal binding domain of Ada 15 77 1.1E-28 T 12-10-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 MIM_c11120 a1e22e76b34cb437f6e341c81aaa7db0 362 SUPERFAMILY SSF53155 194 273 1.96E-21 T 12-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MIM_c11120 a1e22e76b34cb437f6e341c81aaa7db0 362 SUPERFAMILY SSF46767 274 355 3.14E-31 T 12-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 MIM_c11120 a1e22e76b34cb437f6e341c81aaa7db0 362 Gene3D G3DSA:1.10.10.60 85 150 3.2E-25 T 12-10-2018 MIM_c11120 a1e22e76b34cb437f6e341c81aaa7db0 362 Gene3D G3DSA:3.40.10.10 7 80 4.2E-28 T 12-10-2018 IPR035451 Ada-like domain superfamily MIM_c11120 a1e22e76b34cb437f6e341c81aaa7db0 362 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 276 354 4.0E-33 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MIM_c11120 a1e22e76b34cb437f6e341c81aaa7db0 362 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 275 354 2.3E-34 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MIM_c11120 a1e22e76b34cb437f6e341c81aaa7db0 362 SUPERFAMILY SSF57884 10 96 4.71E-28 T 12-10-2018 IPR035451 Ada-like domain superfamily MIM_c11120 a1e22e76b34cb437f6e341c81aaa7db0 362 Gene3D G3DSA:3.30.160.70 181 273 1.2E-30 T 12-10-2018 MIM_c11120 a1e22e76b34cb437f6e341c81aaa7db0 362 Gene3D G3DSA:1.10.10.10 274 358 3.5E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c11120 a1e22e76b34cb437f6e341c81aaa7db0 362 SMART SM00342 104 187 1.7E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c11120 a1e22e76b34cb437f6e341c81aaa7db0 362 PIRSF PIRSF000409 1 362 9.7E-138 T 12-10-2018 IPR016221 Bifunctional regulatory protein Ada MIM_c11120 a1e22e76b34cb437f6e341c81aaa7db0 362 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 325 331 - T 12-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MIM_c09090 cd28d62fbd00b26e5a1a4a87b09cff9f 368 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 193 209 1.3E-4 T 12-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 MIM_c09090 cd28d62fbd00b26e5a1a4a87b09cff9f 368 SMART SM00525 192 212 0.007 T 12-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 MIM_c09090 cd28d62fbd00b26e5a1a4a87b09cff9f 368 Gene3D G3DSA:1.10.340.30 18 129 4.1E-84 T 12-10-2018 MIM_c09090 cd28d62fbd00b26e5a1a4a87b09cff9f 368 Gene3D G3DSA:3.90.79.10 226 356 1.5E-14 T 12-10-2018 MIM_c09090 cd28d62fbd00b26e5a1a4a87b09cff9f 368 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 3 276 3.3E-103 T 12-10-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 MIM_c09090 cd28d62fbd00b26e5a1a4a87b09cff9f 368 SUPERFAMILY SSF55811 221 352 3.27E-20 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MIM_c09090 cd28d62fbd00b26e5a1a4a87b09cff9f 368 Pfam PF14815 NUDIX domain 236 351 7.5E-21 T 12-10-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MIM_c09090 cd28d62fbd00b26e5a1a4a87b09cff9f 368 Pfam PF00633 Helix-hairpin-helix motif 99 125 4.2E-7 T 12-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 MIM_c09090 cd28d62fbd00b26e5a1a4a87b09cff9f 368 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 193 209 - T 12-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MIM_c09090 cd28d62fbd00b26e5a1a4a87b09cff9f 368 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 33 163 4.5E-21 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MIM_c09090 cd28d62fbd00b26e5a1a4a87b09cff9f 368 SMART SM00478 36 191 1.5E-43 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MIM_c09090 cd28d62fbd00b26e5a1a4a87b09cff9f 368 Gene3D G3DSA:1.10.1670.10 7 212 4.1E-84 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 MIM_c09090 cd28d62fbd00b26e5a1a4a87b09cff9f 368 SUPERFAMILY SSF48150 3 225 1.88E-71 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MIM_c22780 d2c6cf75dfdfb60bdfaa8e73a4493200 120 Pfam PF00216 Bacterial DNA-binding protein 1 90 8.7E-27 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MIM_c22780 d2c6cf75dfdfb60bdfaa8e73a4493200 120 Gene3D G3DSA:4.10.520.10 1 93 1.4E-30 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 MIM_c22780 d2c6cf75dfdfb60bdfaa8e73a4493200 120 SUPERFAMILY SSF47729 1 91 3.83E-28 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 MIM_c22780 d2c6cf75dfdfb60bdfaa8e73a4493200 120 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 5.8E-17 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MIM_c22780 d2c6cf75dfdfb60bdfaa8e73a4493200 120 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 5.8E-17 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MIM_c22780 d2c6cf75dfdfb60bdfaa8e73a4493200 120 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 5.8E-17 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MIM_c22780 d2c6cf75dfdfb60bdfaa8e73a4493200 120 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 2 91 1.7E-37 T 12-10-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 MIM_c22780 d2c6cf75dfdfb60bdfaa8e73a4493200 120 SMART SM00411 1 91 4.0E-36 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MIM_c37200 ea94b5866b45915184acbd57379dd0e6 270 SMART SM00346 18 108 8.5E-10 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c37200 ea94b5866b45915184acbd57379dd0e6 270 Gene3D G3DSA:1.10.10.10 18 92 3.7E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c37200 ea94b5866b45915184acbd57379dd0e6 270 Gene3D G3DSA:3.30.450.40 93 267 2.6E-50 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c37200 ea94b5866b45915184acbd57379dd0e6 270 SUPERFAMILY SSF55781 78 263 3.99E-44 T 12-10-2018 MIM_c37200 ea94b5866b45915184acbd57379dd0e6 270 Pfam PF01614 Bacterial transcriptional regulator 135 261 6.4E-29 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal MIM_c37200 ea94b5866b45915184acbd57379dd0e6 270 SUPERFAMILY SSF46785 20 91 7.61E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c37200 ea94b5866b45915184acbd57379dd0e6 270 Pfam PF09339 IclR helix-turn-helix domain 23 68 1.7E-5 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c21230 87c79bbdf7d2d18158d9b5b42f3464cf 502 Gene3D G3DSA:2.20.200.10 102 357 5.1E-138 T 12-10-2018 MIM_c21230 87c79bbdf7d2d18158d9b5b42f3464cf 502 Pfam PF02321 Outer membrane efflux protein 66 257 1.6E-26 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MIM_c21230 87c79bbdf7d2d18158d9b5b42f3464cf 502 Pfam PF02321 Outer membrane efflux protein 287 466 1.3E-24 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MIM_c21230 87c79bbdf7d2d18158d9b5b42f3464cf 502 SUPERFAMILY SSF56954 8 470 1.83E-111 T 12-10-2018 MIM_c21230 87c79bbdf7d2d18158d9b5b42f3464cf 502 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 15 468 7.8E-126 T 12-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 MIM_c21230 87c79bbdf7d2d18158d9b5b42f3464cf 502 Gene3D G3DSA:1.20.1600.10 56 469 5.1E-138 T 12-10-2018 MIM_c17300 1c28b6a3cf76262751ad8ad0f471d35d 420 SUPERFAMILY SSF53187 7 416 2.24E-81 T 12-10-2018 MIM_c17300 1c28b6a3cf76262751ad8ad0f471d35d 420 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 19 416 9.9E-118 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 MIM_c17300 1c28b6a3cf76262751ad8ad0f471d35d 420 SUPERFAMILY SSF55031 223 338 1.2E-22 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain MIM_c17300 1c28b6a3cf76262751ad8ad0f471d35d 420 Gene3D G3DSA:3.40.630.10 23 412 2.9E-133 T 12-10-2018 MIM_c17300 1c28b6a3cf76262751ad8ad0f471d35d 420 Gene3D G3DSA:3.30.70.360 223 336 2.9E-133 T 12-10-2018 MIM_c17300 1c28b6a3cf76262751ad8ad0f471d35d 420 Pfam PF01546 Peptidase family M20/M25/M40 90 415 6.3E-34 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 MIM_c17300 1c28b6a3cf76262751ad8ad0f471d35d 420 PIRSF PIRSF001235 13 420 5.3E-126 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 MIM_c17300 1c28b6a3cf76262751ad8ad0f471d35d 420 Pfam PF07687 Peptidase dimerisation domain 222 317 3.1E-8 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain MIM_c19570 0cf007ab8f68a63cdd288e189c3eb887 382 Gene3D G3DSA:3.90.226.10 4 380 4.4E-118 T 12-10-2018 MIM_c19570 0cf007ab8f68a63cdd288e189c3eb887 382 SUPERFAMILY SSF52096 15 348 9.07E-61 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c19570 0cf007ab8f68a63cdd288e189c3eb887 382 Pfam PF16113 Enoyl-CoA hydratase/isomerase 19 361 8.5E-110 T 12-10-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 MIM_c26780 7e2122dc0e720907daf6f06e8c9d03b4 586 Gene3D G3DSA:2.40.240.10 374 582 9.9E-71 T 12-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MIM_c26780 7e2122dc0e720907daf6f06e8c9d03b4 586 SUPERFAMILY SSF50715 374 584 4.87E-68 T 12-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MIM_c26780 7e2122dc0e720907daf6f06e8c9d03b4 586 Gene3D G3DSA:2.40.240.10 382 501 9.9E-71 T 12-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MIM_c26780 7e2122dc0e720907daf6f06e8c9d03b4 586 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 52 371 1.7E-100 T 12-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 MIM_c26780 7e2122dc0e720907daf6f06e8c9d03b4 586 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 2 585 50.96 T 12-10-2018 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 MIM_c26780 7e2122dc0e720907daf6f06e8c9d03b4 586 Gene3D G3DSA:1.10.1160.10 295 372 2.7E-31 T 12-10-2018 IPR020061 Glutamine-tRNA ligase, alpha-bundle domain superfamily GO:0005524 MIM_c26780 7e2122dc0e720907daf6f06e8c9d03b4 586 Gene3D G3DSA:3.40.50.620 53 277 4.6E-96 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c26780 7e2122dc0e720907daf6f06e8c9d03b4 586 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 374 564 6.7E-50 T 12-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MIM_c26780 7e2122dc0e720907daf6f06e8c9d03b4 586 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 58 69 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c26780 7e2122dc0e720907daf6f06e8c9d03b4 586 Gene3D G3DSA:3.90.800.10 130 238 4.6E-96 T 12-10-2018 MIM_c26780 7e2122dc0e720907daf6f06e8c9d03b4 586 SUPERFAMILY SSF52374 52 379 3.94E-92 T 12-10-2018 MIM_c26780 7e2122dc0e720907daf6f06e8c9d03b4 586 PRINTS PR00987 Glutamyl-tRNA synthetase signature 69 80 3.7E-10 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MIM_c26780 7e2122dc0e720907daf6f06e8c9d03b4 586 PRINTS PR00987 Glutamyl-tRNA synthetase signature 239 249 3.7E-10 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MIM_c26780 7e2122dc0e720907daf6f06e8c9d03b4 586 PRINTS PR00987 Glutamyl-tRNA synthetase signature 84 97 3.7E-10 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MIM_c26780 7e2122dc0e720907daf6f06e8c9d03b4 586 PRINTS PR00987 Glutamyl-tRNA synthetase signature 55 67 3.7E-10 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MIM_c26780 7e2122dc0e720907daf6f06e8c9d03b4 586 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 52 586 8.5E-205 T 12-10-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MIM_c09750 fe564c687a1971a19b0fd400df9706e3 406 Hamap MF_00913 Probable peptidoglycan glycosyltransferase FtsW [ftsW]. 23 396 37.667 T 12-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c09750 fe564c687a1971a19b0fd400df9706e3 406 Pfam PF01098 Cell cycle protein 28 389 2.0E-102 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c09750 fe564c687a1971a19b0fd400df9706e3 406 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 346 370 - T 12-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c09750 fe564c687a1971a19b0fd400df9706e3 406 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 26 387 7.4E-120 T 12-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c16790 6abc1ec171698a9495d5a7e008593aba 271 Gene3D G3DSA:1.10.3720.10 74 266 5.2E-23 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c16790 6abc1ec171698a9495d5a7e008593aba 271 SUPERFAMILY SSF161098 73 257 4.06E-29 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c16790 6abc1ec171698a9495d5a7e008593aba 271 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 265 1.0E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c20100 0566ba361809cb84bb2ed285f6c52157 326 Gene3D G3DSA:3.40.190.10 127 250 1.7E-94 T 12-10-2018 MIM_c20100 0566ba361809cb84bb2ed285f6c52157 326 Gene3D G3DSA:3.40.190.150 31 311 1.7E-94 T 12-10-2018 MIM_c20100 0566ba361809cb84bb2ed285f6c52157 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 322 1.3E-71 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c20100 0566ba361809cb84bb2ed285f6c52157 326 SUPERFAMILY SSF53850 116 288 2.61E-15 T 12-10-2018 MIM_c20100 0566ba361809cb84bb2ed285f6c52157 326 PIRSF PIRSF017082 1 325 7.6E-80 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c26660 1dbc9d56feca5d168ee480e01477ae47 489 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 9 480 3.7E-163 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MIM_c26660 1dbc9d56feca5d168ee480e01477ae47 489 Gene3D G3DSA:3.40.1380.20 345 479 1.9E-160 T 12-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MIM_c26660 1dbc9d56feca5d168ee480e01477ae47 489 SUPERFAMILY SSF52935 332 482 1.68E-34 T 12-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MIM_c26660 1dbc9d56feca5d168ee480e01477ae47 489 ProSitePatterns PS00110 Pyruvate kinase active site signature. 221 233 - T 12-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MIM_c26660 1dbc9d56feca5d168ee480e01477ae47 489 Gene3D G3DSA:2.40.33.10 77 175 1.9E-160 T 12-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MIM_c26660 1dbc9d56feca5d168ee480e01477ae47 489 Gene3D G3DSA:3.20.20.60 9 344 1.9E-160 T 12-10-2018 MIM_c26660 1dbc9d56feca5d168ee480e01477ae47 489 SUPERFAMILY SSF51621 5 349 5.5E-90 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MIM_c26660 1dbc9d56feca5d168ee480e01477ae47 489 PRINTS PR01050 Pyruvate kinase family signature 226 252 4.8E-50 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MIM_c26660 1dbc9d56feca5d168ee480e01477ae47 489 PRINTS PR01050 Pyruvate kinase family signature 253 277 4.8E-50 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MIM_c26660 1dbc9d56feca5d168ee480e01477ae47 489 PRINTS PR01050 Pyruvate kinase family signature 322 338 4.8E-50 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MIM_c26660 1dbc9d56feca5d168ee480e01477ae47 489 PRINTS PR01050 Pyruvate kinase family signature 278 302 4.8E-50 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MIM_c26660 1dbc9d56feca5d168ee480e01477ae47 489 PRINTS PR01050 Pyruvate kinase family signature 303 321 4.8E-50 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MIM_c26660 1dbc9d56feca5d168ee480e01477ae47 489 PRINTS PR01050 Pyruvate kinase family signature 66 82 4.8E-50 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MIM_c26660 1dbc9d56feca5d168ee480e01477ae47 489 PRINTS PR01050 Pyruvate kinase family signature 193 207 4.8E-50 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MIM_c26660 1dbc9d56feca5d168ee480e01477ae47 489 Pfam PF00224 Pyruvate kinase, barrel domain 9 347 6.6E-124 T 12-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MIM_c26660 1dbc9d56feca5d168ee480e01477ae47 489 Pfam PF02887 Pyruvate kinase, alpha/beta domain 366 480 1.1E-25 T 12-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MIM_c26660 1dbc9d56feca5d168ee480e01477ae47 489 SUPERFAMILY SSF50800 77 172 7.67E-25 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily MIM_c12390 d7f92beb8ef3c3501629b1d9a85f19bb 497 Pfam PF10423 Bacterial AMP nucleoside phosphorylase N-terminus 28 182 2.9E-52 T 12-10-2018 IPR018953 AMP nucleoside phosphorylase, N-terminal KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 MIM_c12390 d7f92beb8ef3c3501629b1d9a85f19bb 497 Pfam PF01048 Phosphorylase superfamily 281 442 1.0E-12 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MIM_c12390 d7f92beb8ef3c3501629b1d9a85f19bb 497 Gene3D G3DSA:3.40.50.1580 188 497 3.8E-102 T 12-10-2018 MIM_c12390 d7f92beb8ef3c3501629b1d9a85f19bb 497 SUPERFAMILY SSF53167 26 496 6.2E-147 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 MIM_c12390 d7f92beb8ef3c3501629b1d9a85f19bb 497 TIGRFAM TIGR01717 AMP-nucleosdse: AMP nucleosidase 28 497 3.8E-204 T 12-10-2018 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 MIM_c12390 d7f92beb8ef3c3501629b1d9a85f19bb 497 Gene3D G3DSA:3.30.1730.10 20 185 1.1E-44 T 12-10-2018 IPR037109 AMP nucleoside phosphorylase, N-terminal domain superfamily KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 MIM_c12390 d7f92beb8ef3c3501629b1d9a85f19bb 497 Hamap MF_01932 AMP nucleosidase [amn]. 18 497 59.966 T 12-10-2018 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 MIM_c24140 6402f2c67f6f6c65408e3130862b3b56 391 SUPERFAMILY SSF51690 117 388 2.16E-86 T 12-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MIM_c24140 6402f2c67f6f6c65408e3130862b3b56 391 TIGRFAM TIGR01514 NAPRTase: nicotinate phosphoribosyltransferase 2 389 1.7E-145 T 12-10-2018 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MIM_c24140 6402f2c67f6f6c65408e3130862b3b56 391 Hamap MF_00570 Nicotinate phosphoribosyltransferase [pncB]. 1 390 46.037 T 12-10-2018 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MIM_c24140 6402f2c67f6f6c65408e3130862b3b56 391 SUPERFAMILY SSF54675 1 135 4.41E-42 T 12-10-2018 MIM_c24140 6402f2c67f6f6c65408e3130862b3b56 391 PIRSF PIRSF000484 1 375 2.0E-68 T 12-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 MIM_c24140 6402f2c67f6f6c65408e3130862b3b56 391 Gene3D G3DSA:3.20.140.10 1 391 1.6E-152 T 12-10-2018 MIM_c24140 6402f2c67f6f6c65408e3130862b3b56 391 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 163 389 2.5E-73 T 12-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 MIM_c26630 0911d3ebadbae2ca2ad59ec627b7a01d 244 SUPERFAMILY SSF69593 5 240 2.48E-42 T 12-10-2018 MIM_c26630 0911d3ebadbae2ca2ad59ec627b7a01d 244 Pfam PF01553 Acyltransferase 58 183 2.6E-22 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MIM_c26630 0911d3ebadbae2ca2ad59ec627b7a01d 244 SMART SM00563 71 186 5.0E-26 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MIM_c20900 a6e890077cf0448365461d32f2ff5110 708 SUPERFAMILY SSF56059 489 693 3.53E-26 T 12-10-2018 MIM_c20900 a6e890077cf0448365461d32f2ff5110 708 Gene3D G3DSA:3.30.1490.20 502 574 1.9E-50 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MIM_c20900 a6e890077cf0448365461d32f2ff5110 708 SUPERFAMILY SSF51735 3 139 8.74E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c20900 a6e890077cf0448365461d32f2ff5110 708 Gene3D G3DSA:3.40.50.261 134 299 4.9E-41 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c20900 a6e890077cf0448365461d32f2ff5110 708 Gene3D G3DSA:3.40.50.261 310 468 2.5E-23 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c20900 a6e890077cf0448365461d32f2ff5110 708 SUPERFAMILY SSF52210 136 298 1.13E-32 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c20900 a6e890077cf0448365461d32f2ff5110 708 Pfam PF13549 ATP-grasp domain 491 692 7.4E-38 T 12-10-2018 MIM_c20900 a6e890077cf0448365461d32f2ff5110 708 SUPERFAMILY SSF52210 311 461 5.36E-25 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c20900 a6e890077cf0448365461d32f2ff5110 708 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 162 298 7.4E-39 T 12-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain MIM_c20900 a6e890077cf0448365461d32f2ff5110 708 Gene3D G3DSA:3.30.470.20 490 690 1.9E-50 T 12-10-2018 MIM_c20900 a6e890077cf0448365461d32f2ff5110 708 Pfam PF13380 CoA binding domain 15 137 2.2E-23 T 12-10-2018 IPR003781 CoA-binding GO:0048037 MIM_c20900 a6e890077cf0448365461d32f2ff5110 708 SMART SM00881 10 105 5.4E-37 T 12-10-2018 IPR003781 CoA-binding GO:0048037 MIM_c20900 a6e890077cf0448365461d32f2ff5110 708 Gene3D G3DSA:3.40.50.720 6 133 2.1E-42 T 12-10-2018 MIM_c11180 768753f12b5b0c2c13e327eef5a8b846 232 Pfam PF07729 FCD domain 93 209 2.1E-18 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c11180 768753f12b5b0c2c13e327eef5a8b846 232 SMART SM00345 25 83 1.8E-20 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c11180 768753f12b5b0c2c13e327eef5a8b846 232 SMART SM00895 93 220 6.4E-7 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c11180 768753f12b5b0c2c13e327eef5a8b846 232 Gene3D G3DSA:1.10.10.10 17 84 1.9E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c11180 768753f12b5b0c2c13e327eef5a8b846 232 Gene3D G3DSA:1.20.120.530 87 232 5.0E-20 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c11180 768753f12b5b0c2c13e327eef5a8b846 232 SUPERFAMILY SSF46785 17 87 2.4E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c11180 768753f12b5b0c2c13e327eef5a8b846 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 1.3E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c11180 768753f12b5b0c2c13e327eef5a8b846 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 1.3E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c11180 768753f12b5b0c2c13e327eef5a8b846 232 SUPERFAMILY SSF48008 89 222 1.46E-17 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c11180 768753f12b5b0c2c13e327eef5a8b846 232 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 83 1.6E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c23680 dea7dcc17bb40886cd38adc5fa5bfd45 489 Gene3D G3DSA:2.40.160.60 31 489 9.5E-143 T 12-10-2018 MIM_c23680 dea7dcc17bb40886cd38adc5fa5bfd45 489 SUPERFAMILY SSF56935 31 489 4.52E-88 T 12-10-2018 MIM_c23680 dea7dcc17bb40886cd38adc5fa5bfd45 489 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 25 489 4.2E-111 T 12-10-2018 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) MIM_c40640 2202917a7f57e25c7c3c671805fc3efc 126 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 62 105 2.0E-14 T 12-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c40640 2202917a7f57e25c7c3c671805fc3efc 126 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 52 7.2E-19 T 12-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c40640 2202917a7f57e25c7c3c671805fc3efc 126 SUPERFAMILY SSF48300 4 62 1.19E-15 T 12-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c40640 2202917a7f57e25c7c3c671805fc3efc 126 Gene3D G3DSA:1.20.5.710 3 55 3.7E-20 T 12-10-2018 MIM_c40640 2202917a7f57e25c7c3c671805fc3efc 126 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 126 2.4E-48 T 12-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c40640 2202917a7f57e25c7c3c671805fc3efc 126 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 126 25.747 T 12-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c40640 2202917a7f57e25c7c3c671805fc3efc 126 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 60 126 2.5E-31 T 12-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c40640 2202917a7f57e25c7c3c671805fc3efc 126 SUPERFAMILY SSF54736 56 126 4.01E-25 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MIM_c40640 2202917a7f57e25c7c3c671805fc3efc 126 Gene3D G3DSA:3.30.1390.10 56 126 1.2E-30 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MIM_c21700 72080223b8c740a5bf356732abb031ee 793 Pfam PF13361 UvrD-like helicase C-terminal domain 615 686 5.6E-13 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MIM_c21700 72080223b8c740a5bf356732abb031ee 793 Pfam PF13245 AAA domain 41 497 9.3E-24 T 12-10-2018 MIM_c21700 72080223b8c740a5bf356732abb031ee 793 Gene3D G3DSA:3.40.50.300 522 707 3.8E-23 T 12-10-2018 MIM_c21700 72080223b8c740a5bf356732abb031ee 793 Gene3D G3DSA:3.40.50.300 33 168 6.0E-25 T 12-10-2018 MIM_c21700 72080223b8c740a5bf356732abb031ee 793 Gene3D G3DSA:3.40.50.300 307 514 1.4E-21 T 12-10-2018 MIM_c21700 72080223b8c740a5bf356732abb031ee 793 SUPERFAMILY SSF52540 35 703 5.48E-72 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c20450 eb183b383d3dcb3e2a580a0a52de41e4 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 6.8E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20450 eb183b383d3dcb3e2a580a0a52de41e4 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 6.8E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20450 eb183b383d3dcb3e2a580a0a52de41e4 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 6.8E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20450 eb183b383d3dcb3e2a580a0a52de41e4 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.5E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20450 eb183b383d3dcb3e2a580a0a52de41e4 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.5E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20450 eb183b383d3dcb3e2a580a0a52de41e4 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.5E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20450 eb183b383d3dcb3e2a580a0a52de41e4 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.5E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20450 eb183b383d3dcb3e2a580a0a52de41e4 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.5E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20450 eb183b383d3dcb3e2a580a0a52de41e4 245 Pfam PF00106 short chain dehydrogenase 8 197 4.4E-63 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20450 eb183b383d3dcb3e2a580a0a52de41e4 245 PIRSF PIRSF000126 1 243 3.1E-53 T 12-10-2018 MIM_c20450 eb183b383d3dcb3e2a580a0a52de41e4 245 Gene3D G3DSA:3.40.50.720 2 245 2.8E-74 T 12-10-2018 MIM_c20450 eb183b383d3dcb3e2a580a0a52de41e4 245 SUPERFAMILY SSF51735 2 229 1.33E-73 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c20450 eb183b383d3dcb3e2a580a0a52de41e4 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 190 1.1E-4 T 12-10-2018 MIM_c20450 eb183b383d3dcb3e2a580a0a52de41e4 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c34540 b3dfb8af72073642f5ae9120a268f81c 311 Gene3D G3DSA:2.120.10.30 5 305 1.2E-97 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MIM_c34540 b3dfb8af72073642f5ae9120a268f81c 311 SUPERFAMILY SSF63829 4 309 4.14E-64 T 12-10-2018 MIM_c34540 b3dfb8af72073642f5ae9120a268f81c 311 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 39 296 8.2E-61 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region MIM_c34540 b3dfb8af72073642f5ae9120a268f81c 311 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 40 57 4.6E-12 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MIM_c34540 b3dfb8af72073642f5ae9120a268f81c 311 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 279 297 4.6E-12 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MIM_c34540 b3dfb8af72073642f5ae9120a268f81c 311 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 234 251 4.6E-12 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MIM_c34540 b3dfb8af72073642f5ae9120a268f81c 311 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 170 192 4.6E-12 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MIM_c34060 8ed89aec5a4f5bbaac3c8ce8c8f5aee2 313 Pfam PF00005 ABC transporter 35 175 8.3E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c34060 8ed89aec5a4f5bbaac3c8ce8c8f5aee2 313 Gene3D G3DSA:3.40.50.300 15 275 3.8E-66 T 12-10-2018 MIM_c34060 8ed89aec5a4f5bbaac3c8ce8c8f5aee2 313 SMART SM00382 43 225 3.3E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c34060 8ed89aec5a4f5bbaac3c8ce8c8f5aee2 313 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c34060 8ed89aec5a4f5bbaac3c8ce8c8f5aee2 313 SUPERFAMILY SSF52540 16 234 6.01E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c34060 8ed89aec5a4f5bbaac3c8ce8c8f5aee2 313 TIGRFAM TIGR01184 ntrCD: nitrate ABC transporter, ATP-binding proteins C and D 35 263 1.0E-94 T 12-10-2018 IPR005890 Nitrate transport ATP-binding subunit C/D GO:0015112|GO:0015706|GO:0016020 MIM_c40990 4d2c23d1488c9571d01712f9308ca36b 162 SUPERFAMILY SSF69118 6 145 7.59E-42 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c40990 4d2c23d1488c9571d01712f9308ca36b 162 Pfam PF02627 Carboxymuconolactone decarboxylase family 12 95 1.4E-21 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c40990 4d2c23d1488c9571d01712f9308ca36b 162 Gene3D G3DSA:1.20.1290.10 1 153 9.3E-45 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c40990 4d2c23d1488c9571d01712f9308ca36b 162 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 31 78 1.4E-14 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c05770 dd27886c98d5c0408f409e2c16288d2c 164 Gene3D G3DSA:3.40.50.620 28 161 2.9E-30 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c05770 dd27886c98d5c0408f409e2c16288d2c 164 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 29 91 1.4E-13 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MIM_c05770 dd27886c98d5c0408f409e2c16288d2c 164 Pfam PF01467 Cytidylyltransferase-like 31 126 8.2E-16 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MIM_c05770 dd27886c98d5c0408f409e2c16288d2c 164 SUPERFAMILY SSF52374 27 157 6.22E-23 T 12-10-2018 MIM_c13500 b33a5836b1c32168c8741aebd186b0c6 257 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 1 230 34.023 T 12-10-2018 IPR017689 Outer membrane protein assembly factor BamD MIM_c13500 b33a5836b1c32168c8741aebd186b0c6 257 Gene3D G3DSA:1.25.40.10 19 240 4.1E-52 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MIM_c13500 b33a5836b1c32168c8741aebd186b0c6 257 Pfam PF13525 Outer membrane lipoprotein 18 224 8.5E-60 T 12-10-2018 IPR039565 Outer membrane lipoprotein BamD-like MIM_c13500 b33a5836b1c32168c8741aebd186b0c6 257 SUPERFAMILY SSF48452 21 97 8.07E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MIM_c13500 b33a5836b1c32168c8741aebd186b0c6 257 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 1 236 1.7E-75 T 12-10-2018 IPR017689 Outer membrane protein assembly factor BamD MIM_c29520 a7061915d1f0a2ca869dac3e21fa3778 272 Gene3D G3DSA:3.60.21.10 1 272 9.7E-72 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like MIM_c29520 a7061915d1f0a2ca869dac3e21fa3778 272 Pfam PF00149 Calcineurin-like phosphoesterase 1 150 2.7E-11 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MIM_c29520 a7061915d1f0a2ca869dac3e21fa3778 272 SUPERFAMILY SSF56300 1 257 2.03E-47 T 12-10-2018 MIM_c29520 a7061915d1f0a2ca869dac3e21fa3778 272 PIRSF PIRSF000903 1 272 1.3E-100 T 12-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 MIM_c29520 a7061915d1f0a2ca869dac3e21fa3778 272 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 1 268 5.6E-72 T 12-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 MIM_c17740 8f06e881fb8f27908500582c9be75c4e 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 8.5E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c17740 8f06e881fb8f27908500582c9be75c4e 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 8.5E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c17740 8f06e881fb8f27908500582c9be75c4e 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 8.5E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c17740 8f06e881fb8f27908500582c9be75c4e 306 SUPERFAMILY SSF46785 3 112 9.7E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c17740 8f06e881fb8f27908500582c9be75c4e 306 SUPERFAMILY SSF53850 92 296 3.91E-38 T 12-10-2018 MIM_c17740 8f06e881fb8f27908500582c9be75c4e 306 Pfam PF03466 LysR substrate binding domain 90 291 3.0E-37 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c17740 8f06e881fb8f27908500582c9be75c4e 306 Gene3D G3DSA:1.10.10.10 4 93 9.8E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c17740 8f06e881fb8f27908500582c9be75c4e 306 Gene3D G3DSA:3.40.190.290 94 299 6.4E-38 T 12-10-2018 MIM_c17740 8f06e881fb8f27908500582c9be75c4e 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 5.4E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_24p00060 d79d793bf3655568a8da18009f167a04 227 SUPERFAMILY SSF53098 52 216 3.29E-43 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily MIM_24p00060 d79d793bf3655568a8da18009f167a04 227 Pfam PF00665 Integrase core domain 60 173 5.0E-35 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 MIM_24p00060 d79d793bf3655568a8da18009f167a04 227 Gene3D G3DSA:3.30.420.10 57 219 9.9E-19 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MIM_c29540 6fc2d0f866437d226fa02ec8c6eea6eb 430 Gene3D G3DSA:2.30.40.10 9 426 2.4E-108 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MIM_c29540 6fc2d0f866437d226fa02ec8c6eea6eb 430 SUPERFAMILY SSF51556 56 362 8.96E-84 T 12-10-2018 IPR032466 Metal-dependent hydrolase MIM_c29540 6fc2d0f866437d226fa02ec8c6eea6eb 430 SUPERFAMILY SSF51338 2 428 4.32E-28 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MIM_c29540 6fc2d0f866437d226fa02ec8c6eea6eb 430 Pfam PF01979 Amidohydrolase family 52 426 2.5E-10 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MIM_c29540 6fc2d0f866437d226fa02ec8c6eea6eb 430 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 40 427 3.1E-88 T 12-10-2018 MIM_c29540 6fc2d0f866437d226fa02ec8c6eea6eb 430 Gene3D G3DSA:3.20.20.140 57 367 2.4E-108 T 12-10-2018 MIM_c22750 e8b8d329a7925c8865c6b4b989f00962 309 Gene3D G3DSA:3.40.1190.20 2 309 6.2E-116 T 12-10-2018 IPR029056 Ribokinase-like MIM_c22750 e8b8d329a7925c8865c6b4b989f00962 309 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 52 75 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MIM_c22750 e8b8d329a7925c8865c6b4b989f00962 309 SUPERFAMILY SSF53613 12 308 7.64E-59 T 12-10-2018 IPR029056 Ribokinase-like MIM_c22750 e8b8d329a7925c8865c6b4b989f00962 309 TIGRFAM TIGR02198 rfaE_dom_I: bifunctional protein RfaE, domain I 6 309 1.0E-121 T 12-10-2018 IPR011913 RfaE bifunctional protein, domain I GO:0005975|GO:0016773|GO:0016779 KEGG: 00540+2.7.7.70+2.7.1.167 MIM_c22750 e8b8d329a7925c8865c6b4b989f00962 309 Pfam PF00294 pfkB family carbohydrate kinase 12 302 1.2E-43 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB MIM_c13990 7988fbaec3c64d4d865fa9b3c67805bf 334 SUPERFAMILY SSF53850 121 297 4.34E-10 T 12-10-2018 MIM_c13990 7988fbaec3c64d4d865fa9b3c67805bf 334 Gene3D G3DSA:3.40.190.10 136 259 2.0E-108 T 12-10-2018 MIM_c13990 7988fbaec3c64d4d865fa9b3c67805bf 334 Gene3D G3DSA:3.40.190.150 39 324 2.0E-108 T 12-10-2018 MIM_c13990 7988fbaec3c64d4d865fa9b3c67805bf 334 PIRSF PIRSF017082 6 334 2.6E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c13990 7988fbaec3c64d4d865fa9b3c67805bf 334 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 58 330 4.8E-81 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c08150 e58d1ef7fc2765149b5907f7237aacc1 354 Gene3D G3DSA:1.10.260.40 9 71 8.2E-16 T 12-10-2018 MIM_c08150 e58d1ef7fc2765149b5907f7237aacc1 354 Pfam PF13407 Periplasmic binding protein domain 131 325 4.0E-36 T 12-10-2018 IPR025997 Periplasmic binding protein MIM_c08150 e58d1ef7fc2765149b5907f7237aacc1 354 Gene3D G3DSA:3.40.50.2300 180 353 3.5E-39 T 12-10-2018 MIM_c08150 e58d1ef7fc2765149b5907f7237aacc1 354 Pfam PF00356 Bacterial regulatory proteins, lacI family 19 62 9.6E-15 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MIM_c08150 e58d1ef7fc2765149b5907f7237aacc1 354 SUPERFAMILY SSF47413 16 63 3.47E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c08150 e58d1ef7fc2765149b5907f7237aacc1 354 SUPERFAMILY SSF53822 76 346 5.1E-38 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c08150 e58d1ef7fc2765149b5907f7237aacc1 354 ProSitePatterns PS00356 LacI-type HTH domain signature. 19 37 - T 12-10-2018 MIM_c08150 e58d1ef7fc2765149b5907f7237aacc1 354 Gene3D G3DSA:3.40.50.2300 100 344 3.5E-39 T 12-10-2018 MIM_c08150 e58d1ef7fc2765149b5907f7237aacc1 354 SMART SM00354 16 86 4.7E-11 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MIM_c17660 e043590df1d49b80cd83ab9dcec6f8af 255 SMART SM00346 11 101 3.7E-20 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c17660 e043590df1d49b80cd83ab9dcec6f8af 255 Pfam PF01614 Bacterial transcriptional regulator 143 241 1.1E-14 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal MIM_c17660 e043590df1d49b80cd83ab9dcec6f8af 255 SUPERFAMILY SSF46785 11 83 1.19E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c17660 e043590df1d49b80cd83ab9dcec6f8af 255 Pfam PF09339 IclR helix-turn-helix domain 13 61 4.3E-12 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c17660 e043590df1d49b80cd83ab9dcec6f8af 255 Gene3D G3DSA:1.10.10.10 5 80 4.0E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c17660 e043590df1d49b80cd83ab9dcec6f8af 255 SUPERFAMILY SSF55781 69 250 6.54E-35 T 12-10-2018 MIM_c17660 e043590df1d49b80cd83ab9dcec6f8af 255 Gene3D G3DSA:3.30.450.40 81 242 1.1E-37 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c13230 e1031dd77cba38106f32ed1a08f2e7af 137 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 7 131 1.3E-32 T 12-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MIM_c13230 e1031dd77cba38106f32ed1a08f2e7af 137 SUPERFAMILY SSF81343 2 133 1.06E-24 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MIM_c13230 e1031dd77cba38106f32ed1a08f2e7af 137 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 7 129 2.0E-26 T 12-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MIM_c13230 e1031dd77cba38106f32ed1a08f2e7af 137 PIRSF PIRSF000178 3 134 1.0E-25 T 12-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MIM_c13230 e1031dd77cba38106f32ed1a08f2e7af 137 Gene3D G3DSA:1.20.1300.10 3 134 1.4E-31 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MIM_c03590 d1e7a1105bdaee5555a1b6d97bde6d03 158 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MIM_c03590 d1e7a1105bdaee5555a1b6d97bde6d03 158 Pfam PF00210 Ferritin-like domain 9 141 5.5E-35 T 12-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 MIM_c03590 d1e7a1105bdaee5555a1b6d97bde6d03 158 Gene3D G3DSA:1.20.1260.10 1 158 4.0E-62 T 12-10-2018 IPR012347 Ferritin-like MIM_c03590 d1e7a1105bdaee5555a1b6d97bde6d03 158 PIRSF PIRSF002560 1 157 7.6E-67 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MIM_c03590 d1e7a1105bdaee5555a1b6d97bde6d03 158 PRINTS PR00601 Bacterioferritin signature 107 127 3.6E-61 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MIM_c03590 d1e7a1105bdaee5555a1b6d97bde6d03 158 PRINTS PR00601 Bacterioferritin signature 65 85 3.6E-61 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MIM_c03590 d1e7a1105bdaee5555a1b6d97bde6d03 158 PRINTS PR00601 Bacterioferritin signature 23 43 3.6E-61 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MIM_c03590 d1e7a1105bdaee5555a1b6d97bde6d03 158 PRINTS PR00601 Bacterioferritin signature 3 22 3.6E-61 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MIM_c03590 d1e7a1105bdaee5555a1b6d97bde6d03 158 PRINTS PR00601 Bacterioferritin signature 44 64 3.6E-61 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MIM_c03590 d1e7a1105bdaee5555a1b6d97bde6d03 158 PRINTS PR00601 Bacterioferritin signature 128 149 3.6E-61 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MIM_c03590 d1e7a1105bdaee5555a1b6d97bde6d03 158 PRINTS PR00601 Bacterioferritin signature 86 106 3.6E-61 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MIM_c03590 d1e7a1105bdaee5555a1b6d97bde6d03 158 TIGRFAM TIGR00754 bfr: bacterioferritin 1 156 7.5E-71 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MIM_c03590 d1e7a1105bdaee5555a1b6d97bde6d03 158 SUPERFAMILY SSF47240 1 156 6.55E-48 T 12-10-2018 IPR009078 Ferritin-like superfamily MIM_c01790 236b3db0ab57d6a1c32c939e6f6c3462 365 SUPERFAMILY SSF46689 317 364 1.43E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c01790 236b3db0ab57d6a1c32c939e6f6c3462 365 SMART SM00342 280 362 6.7E-28 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c01790 236b3db0ab57d6a1c32c939e6f6c3462 365 Gene3D G3DSA:1.10.10.60 260 365 1.7E-24 T 12-10-2018 MIM_c01790 236b3db0ab57d6a1c32c939e6f6c3462 365 Pfam PF12833 Helix-turn-helix domain 286 364 5.0E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c01790 236b3db0ab57d6a1c32c939e6f6c3462 365 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 317 358 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MIM_c01790 236b3db0ab57d6a1c32c939e6f6c3462 365 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 331 346 1.2E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MIM_c01790 236b3db0ab57d6a1c32c939e6f6c3462 365 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 346 362 1.2E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MIM_c01790 236b3db0ab57d6a1c32c939e6f6c3462 365 SUPERFAMILY SSF46689 272 314 1.79E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c37410 7069056ae94b8fa6a69732f2aaddc062 286 SUPERFAMILY SSF53850 88 282 2.79E-28 T 12-10-2018 MIM_c37410 7069056ae94b8fa6a69732f2aaddc062 286 Gene3D G3DSA:3.40.190.10 162 255 7.7E-52 T 12-10-2018 MIM_c37410 7069056ae94b8fa6a69732f2aaddc062 286 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 4.4E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c37410 7069056ae94b8fa6a69732f2aaddc062 286 Gene3D G3DSA:1.10.10.10 4 94 1.9E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c37410 7069056ae94b8fa6a69732f2aaddc062 286 SUPERFAMILY SSF46785 4 111 1.11E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c37410 7069056ae94b8fa6a69732f2aaddc062 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c37410 7069056ae94b8fa6a69732f2aaddc062 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c37410 7069056ae94b8fa6a69732f2aaddc062 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c37410 7069056ae94b8fa6a69732f2aaddc062 286 Pfam PF03466 LysR substrate binding domain 88 281 6.8E-26 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c37410 7069056ae94b8fa6a69732f2aaddc062 286 Gene3D G3DSA:3.40.190.10 96 262 7.7E-52 T 12-10-2018 MIM_c03610 79067c576062e6bfe0b0312484bef8d0 538 SUPERFAMILY SSF54980 391 462 3.6E-16 T 12-10-2018 IPR035647 EF-G domain III/V-like MIM_c03610 79067c576062e6bfe0b0312484bef8d0 538 Gene3D G3DSA:3.40.50.300 14 376 2.7E-105 T 12-10-2018 MIM_c03610 79067c576062e6bfe0b0312484bef8d0 538 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 4 527 51.212 T 12-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 MIM_c03610 79067c576062e6bfe0b0312484bef8d0 538 PRINTS PR00315 GTP-binding elongation factor signature 101 112 2.4E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c03610 79067c576062e6bfe0b0312484bef8d0 538 PRINTS PR00315 GTP-binding elongation factor signature 137 146 2.4E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c03610 79067c576062e6bfe0b0312484bef8d0 538 PRINTS PR00315 GTP-binding elongation factor signature 65 73 2.4E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c03610 79067c576062e6bfe0b0312484bef8d0 538 PRINTS PR00315 GTP-binding elongation factor signature 15 28 2.4E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c03610 79067c576062e6bfe0b0312484bef8d0 538 PRINTS PR00315 GTP-binding elongation factor signature 85 95 2.4E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c03610 79067c576062e6bfe0b0312484bef8d0 538 Pfam PF16658 Class II release factor RF3, C-terminal domain 386 514 4.2E-44 T 12-10-2018 IPR032090 Peptide chain release factor 3, C-terminal MIM_c03610 79067c576062e6bfe0b0312484bef8d0 538 SUPERFAMILY SSF52540 10 276 4.63E-87 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c03610 79067c576062e6bfe0b0312484bef8d0 538 Gene3D G3DSA:3.30.70.3280 389 529 2.2E-47 T 12-10-2018 IPR038467 Peptide chain release factor 3, C-terminal domain superfamily MIM_c03610 79067c576062e6bfe0b0312484bef8d0 538 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 58 73 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site MIM_c03610 79067c576062e6bfe0b0312484bef8d0 538 Gene3D G3DSA:3.40.50.300 21 274 2.7E-105 T 12-10-2018 MIM_c03610 79067c576062e6bfe0b0312484bef8d0 538 Pfam PF00009 Elongation factor Tu GTP binding domain 13 276 2.0E-51 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c03610 79067c576062e6bfe0b0312484bef8d0 538 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 8 529 4.4E-215 T 12-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 MIM_c03610 79067c576062e6bfe0b0312484bef8d0 538 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 16 148 3.3E-22 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MIM_c03610 79067c576062e6bfe0b0312484bef8d0 538 SUPERFAMILY SSF50447 260 390 4.71E-26 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MIM_c00720 dca637f3ae0d645ce9be3e910fe0b9be 231 Pfam PF06635 Nodulation protein NolV 47 214 6.2E-10 T 12-10-2018 IPR010586 Nodulation NolV GO:0009877 MIM_c34630 c8387137928a4166c29d4e19a47a8e33 335 Gene3D G3DSA:3.40.190.10 124 212 4.1E-21 T 12-10-2018 MIM_c34630 c8387137928a4166c29d4e19a47a8e33 335 Gene3D G3DSA:3.40.190.10 30 123 2.6E-11 T 12-10-2018 MIM_c34630 c8387137928a4166c29d4e19a47a8e33 335 Gene3D G3DSA:3.40.190.10 217 335 9.1E-10 T 12-10-2018 MIM_c34630 c8387137928a4166c29d4e19a47a8e33 335 Pfam PF09084 NMT1/THI5 like 46 263 4.0E-25 T 12-10-2018 IPR015168 SsuA/THI5-like MIM_c34630 c8387137928a4166c29d4e19a47a8e33 335 SUPERFAMILY SSF53850 37 275 1.37E-42 T 12-10-2018 MIM_c31410 ffdd7dda080510b2fd710f36ba3d5540 229 Gene3D G3DSA:1.20.1290.10 129 217 7.5E-18 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c31410 ffdd7dda080510b2fd710f36ba3d5540 229 SUPERFAMILY SSF69118 16 150 5.37E-8 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c31410 ffdd7dda080510b2fd710f36ba3d5540 229 SUPERFAMILY SSF69118 129 212 7.72E-19 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c31410 ffdd7dda080510b2fd710f36ba3d5540 229 Gene3D G3DSA:1.20.1290.10 1 112 1.4E-7 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c31410 ffdd7dda080510b2fd710f36ba3d5540 229 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 163 206 4.4E-16 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c31410 ffdd7dda080510b2fd710f36ba3d5540 229 Pfam PF02627 Carboxymuconolactone decarboxylase family 143 208 2.8E-12 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c31500 bc6cafab20c99e9206ba8ca318d8dca9 301 Gene3D G3DSA:3.40.190.10 177 275 8.5E-15 T 12-10-2018 MIM_c31500 bc6cafab20c99e9206ba8ca318d8dca9 301 Pfam PF03466 LysR substrate binding domain 97 299 4.7E-23 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c31500 bc6cafab20c99e9206ba8ca318d8dca9 301 Gene3D G3DSA:3.40.190.10 118 285 8.5E-15 T 12-10-2018 MIM_c31500 bc6cafab20c99e9206ba8ca318d8dca9 301 Gene3D G3DSA:1.10.10.10 11 100 2.3E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c31500 bc6cafab20c99e9206ba8ca318d8dca9 301 SUPERFAMILY SSF53850 99 300 1.36E-22 T 12-10-2018 MIM_c31500 bc6cafab20c99e9206ba8ca318d8dca9 301 SUPERFAMILY SSF46785 11 97 5.09E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c31500 bc6cafab20c99e9206ba8ca318d8dca9 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 72 1.1E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c08610 3288cb078889b567429f64aa1f5a2d49 371 Gene3D G3DSA:3.50.50.60 8 357 9.6E-94 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c08610 3288cb078889b567429f64aa1f5a2d49 371 Pfam PF01266 FAD dependent oxidoreductase 8 351 3.1E-62 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MIM_c08610 3288cb078889b567429f64aa1f5a2d49 371 Gene3D G3DSA:3.30.9.10 87 315 9.6E-94 T 12-10-2018 MIM_c08610 3288cb078889b567429f64aa1f5a2d49 371 SUPERFAMILY SSF51905 6 370 3.04E-57 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c04640 10dc2a2ba1582b39cf57018bf8adb9ce 292 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 260 286 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MIM_c04640 10dc2a2ba1582b39cf57018bf8adb9ce 292 Pfam PF04545 Sigma-70, region 4 235 287 2.2E-16 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 MIM_c04640 10dc2a2ba1582b39cf57018bf8adb9ce 292 SUPERFAMILY SSF88659 196 290 1.53E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MIM_c04640 10dc2a2ba1582b39cf57018bf8adb9ce 292 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 5 292 49.712 T 12-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 MIM_c04640 10dc2a2ba1582b39cf57018bf8adb9ce 292 PRINTS PR00046 Major sigma-70 factor signature 239 251 5.9E-19 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MIM_c04640 10dc2a2ba1582b39cf57018bf8adb9ce 292 PRINTS PR00046 Major sigma-70 factor signature 260 275 5.9E-19 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MIM_c04640 10dc2a2ba1582b39cf57018bf8adb9ce 292 PRINTS PR00046 Major sigma-70 factor signature 275 286 5.9E-19 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MIM_c04640 10dc2a2ba1582b39cf57018bf8adb9ce 292 PRINTS PR00046 Major sigma-70 factor signature 86 99 5.9E-19 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MIM_c04640 10dc2a2ba1582b39cf57018bf8adb9ce 292 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 58 288 4.0E-31 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MIM_c04640 10dc2a2ba1582b39cf57018bf8adb9ce 292 Pfam PF04542 Sigma-70 region 2 62 131 1.5E-16 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MIM_c04640 10dc2a2ba1582b39cf57018bf8adb9ce 292 SUPERFAMILY SSF88946 24 131 9.42E-39 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MIM_c04640 10dc2a2ba1582b39cf57018bf8adb9ce 292 Gene3D G3DSA:1.10.601.10 8 134 2.8E-30 T 12-10-2018 MIM_c04640 10dc2a2ba1582b39cf57018bf8adb9ce 292 Gene3D G3DSA:1.10.10.10 220 290 1.6E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c04640 10dc2a2ba1582b39cf57018bf8adb9ce 292 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 86 99 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MIM_c04640 10dc2a2ba1582b39cf57018bf8adb9ce 292 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 24 290 1.9E-117 T 12-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 MIM_c12880 ecbc2bb7f33947a8925e00115ed38148 312 Gene3D G3DSA:1.10.10.10 9 95 3.9E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c12880 ecbc2bb7f33947a8925e00115ed38148 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 1.5E-14 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c12880 ecbc2bb7f33947a8925e00115ed38148 312 SUPERFAMILY SSF46785 11 118 3.11E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c12880 ecbc2bb7f33947a8925e00115ed38148 312 Pfam PF03466 LysR substrate binding domain 94 296 2.0E-37 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c12880 ecbc2bb7f33947a8925e00115ed38148 312 SUPERFAMILY SSF53850 95 297 1.07E-39 T 12-10-2018 MIM_c12880 ecbc2bb7f33947a8925e00115ed38148 312 Gene3D G3DSA:3.40.190.290 97 299 7.8E-58 T 12-10-2018 MIM_c25930 e5cd0cc16b5a00c286d79266a06d420c 338 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 319 1.3E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c25930 e5cd0cc16b5a00c286d79266a06d420c 338 Gene3D G3DSA:1.10.3720.10 91 333 2.5E-32 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c25930 e5cd0cc16b5a00c286d79266a06d420c 338 SUPERFAMILY SSF161098 46 321 1.23E-33 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c25930 e5cd0cc16b5a00c286d79266a06d420c 338 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 37 330 2.6E-93 T 12-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 MIM_c28400 330f4c69982b9f7ef8285cd0a5df3021 287 SUPERFAMILY SSF103481 183 281 7.72E-8 T 12-10-2018 MIM_c28400 330f4c69982b9f7ef8285cd0a5df3021 287 SUPERFAMILY SSF103481 42 135 1.18E-5 T 12-10-2018 MIM_c09680 adbda34e1c64aa0fd53fc992d4727ce8 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 44.141 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 MIM_c09680 adbda34e1c64aa0fd53fc992d4727ce8 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 3 131 7.6E-33 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 MIM_c09680 adbda34e1c64aa0fd53fc992d4727ce8 143 Gene3D G3DSA:2.40.330.20 1 139 2.8E-35 T 12-10-2018 IPR038619 MraZ superfamily MIM_c09680 adbda34e1c64aa0fd53fc992d4727ce8 143 Pfam PF02381 MraZ protein, putative antitoxin-like 2 67 1.2E-10 T 12-10-2018 IPR020603 MraZ domain MIM_c09680 adbda34e1c64aa0fd53fc992d4727ce8 143 Pfam PF02381 MraZ protein, putative antitoxin-like 74 131 1.7E-11 T 12-10-2018 IPR020603 MraZ domain MIM_c09680 adbda34e1c64aa0fd53fc992d4727ce8 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 2 118 3.0E-45 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 MIM_c09680 adbda34e1c64aa0fd53fc992d4727ce8 143 SUPERFAMILY SSF89447 2 130 2.24E-35 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily MIM_c19340 c05a9ec5e4d87e4962ae0e9d55a6b6ac 291 ProSitePatterns PS01127 Elongation factor Ts signature 2. 77 87 - T 12-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MIM_c19340 c05a9ec5e4d87e4962ae0e9d55a6b6ac 291 SUPERFAMILY SSF54713 151 288 1.18E-44 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 MIM_c19340 c05a9ec5e4d87e4962ae0e9d55a6b6ac 291 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 287 4.1E-92 T 12-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MIM_c19340 c05a9ec5e4d87e4962ae0e9d55a6b6ac 291 SUPERFAMILY SSF54713 56 147 3.6E-23 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 MIM_c19340 c05a9ec5e4d87e4962ae0e9d55a6b6ac 291 Hamap MF_00050 Elongation factor Ts [tsf]. 1 288 76.358 T 12-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MIM_c19340 c05a9ec5e4d87e4962ae0e9d55a6b6ac 291 Gene3D G3DSA:3.30.479.20 57 153 7.2E-27 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 MIM_c19340 c05a9ec5e4d87e4962ae0e9d55a6b6ac 291 Gene3D G3DSA:3.30.479.20 155 270 5.8E-36 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 MIM_c19340 c05a9ec5e4d87e4962ae0e9d55a6b6ac 291 Pfam PF00889 Elongation factor TS 73 271 5.1E-66 T 12-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 MIM_c19340 c05a9ec5e4d87e4962ae0e9d55a6b6ac 291 SUPERFAMILY SSF46934 4 56 3.78E-14 T 12-10-2018 IPR009060 UBA-like superfamily GO:0005515 MIM_c19340 c05a9ec5e4d87e4962ae0e9d55a6b6ac 291 Gene3D G3DSA:1.10.8.10 1 56 1.3E-21 T 12-10-2018 MIM_c19340 c05a9ec5e4d87e4962ae0e9d55a6b6ac 291 Gene3D G3DSA:1.10.286.20 190 236 5.8E-36 T 12-10-2018 MIM_c15870 fc84b60ffe5f7de4aa7a654f9840e76b 102 SUPERFAMILY SSF54736 15 99 2.72E-32 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MIM_c15870 fc84b60ffe5f7de4aa7a654f9840e76b 102 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 2 95 28.705 T 12-10-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS MIM_c15870 fc84b60ffe5f7de4aa7a654f9840e76b 102 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 18 95 5.5E-36 T 12-10-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 MIM_c15870 fc84b60ffe5f7de4aa7a654f9840e76b 102 Gene3D G3DSA:3.30.1390.10 1 101 2.2E-44 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MIM_c40180 8a6c839517c5f9aae8ae09c92bf7719a 319 SUPERFAMILY SSF46689 218 266 2.78E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c40180 8a6c839517c5f9aae8ae09c92bf7719a 319 SMART SM00342 232 315 1.9E-25 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c40180 8a6c839517c5f9aae8ae09c92bf7719a 319 Pfam PF12833 Helix-turn-helix domain 238 317 6.1E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c40180 8a6c839517c5f9aae8ae09c92bf7719a 319 Gene3D G3DSA:1.10.10.60 217 319 1.8E-27 T 12-10-2018 MIM_c40180 8a6c839517c5f9aae8ae09c92bf7719a 319 Pfam PF01965 DJ-1/PfpI family 40 177 2.7E-12 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 MIM_c40180 8a6c839517c5f9aae8ae09c92bf7719a 319 Gene3D G3DSA:3.40.50.880 1 201 5.1E-40 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c40180 8a6c839517c5f9aae8ae09c92bf7719a 319 SUPERFAMILY SSF52317 1 196 3.88E-34 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c40180 8a6c839517c5f9aae8ae09c92bf7719a 319 SUPERFAMILY SSF46689 268 318 2.11E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c11290 b493ab2a0c555ae84a013410c3a0fa4c 378 Gene3D G3DSA:3.40.50.300 3 239 2.5E-62 T 12-10-2018 MIM_c11290 b493ab2a0c555ae84a013410c3a0fa4c 378 SMART SM00382 28 229 2.9E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c11290 b493ab2a0c555ae84a013410c3a0fa4c 378 Pfam PF00005 ABC transporter 19 179 4.8E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c11290 b493ab2a0c555ae84a013410c3a0fa4c 378 Pfam PF08402 TOBE domain 288 360 1.1E-5 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 MIM_c11290 b493ab2a0c555ae84a013410c3a0fa4c 378 Gene3D G3DSA:2.40.50.940 240 361 1.3E-14 T 12-10-2018 MIM_c11290 b493ab2a0c555ae84a013410c3a0fa4c 378 SUPERFAMILY SSF50331 255 367 9.18E-15 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MIM_c11290 b493ab2a0c555ae84a013410c3a0fa4c 378 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c11290 b493ab2a0c555ae84a013410c3a0fa4c 378 Gene3D G3DSA:2.40.50.140 295 352 1.3E-14 T 12-10-2018 MIM_c11290 b493ab2a0c555ae84a013410c3a0fa4c 378 SUPERFAMILY SSF52540 4 262 5.56E-77 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c02480 a859568c7290be779212d0df67a20ea2 310 SUPERFAMILY SSF51569 3 280 2.56E-64 T 12-10-2018 MIM_c02480 a859568c7290be779212d0df67a20ea2 310 Gene3D G3DSA:3.20.20.70 5 292 4.6E-105 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c02480 a859568c7290be779212d0df67a20ea2 310 Pfam PF00682 HMGL-like 9 278 4.0E-45 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 MIM_c29030 29443f190488e18f4a1e5502096947d2 345 SUPERFAMILY SSF46689 291 341 8.51E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c29030 29443f190488e18f4a1e5502096947d2 345 SUPERFAMILY SSF46689 240 287 1.43E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c29030 29443f190488e18f4a1e5502096947d2 345 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 291 333 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MIM_c29030 29443f190488e18f4a1e5502096947d2 345 Gene3D G3DSA:1.10.10.60 240 344 3.9E-27 T 12-10-2018 MIM_c29030 29443f190488e18f4a1e5502096947d2 345 SMART SM00342 254 337 1.1E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c29030 29443f190488e18f4a1e5502096947d2 345 Pfam PF01965 DJ-1/PfpI family 21 199 2.0E-19 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 MIM_c29030 29443f190488e18f4a1e5502096947d2 345 Pfam PF12833 Helix-turn-helix domain 260 339 1.9E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c29030 29443f190488e18f4a1e5502096947d2 345 Gene3D G3DSA:3.40.50.880 17 239 1.6E-56 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c29030 29443f190488e18f4a1e5502096947d2 345 SUPERFAMILY SSF52317 20 218 1.3E-42 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c11530 999a4cb82539da590b3dddf13ee2b19a 329 Gene3D G3DSA:3.40.50.1400 164 302 1.9E-93 T 12-10-2018 MIM_c11530 999a4cb82539da590b3dddf13ee2b19a 329 SUPERFAMILY SSF53800 2 325 7.03E-97 T 12-10-2018 MIM_c11530 999a4cb82539da590b3dddf13ee2b19a 329 Gene3D G3DSA:3.40.50.1400 3 321 1.9E-93 T 12-10-2018 MIM_c11530 999a4cb82539da590b3dddf13ee2b19a 329 ProSitePatterns PS00534 Ferrochelatase signature. 190 208 - T 12-10-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MIM_c11530 999a4cb82539da590b3dddf13ee2b19a 329 TIGRFAM TIGR00109 hemH: ferrochelatase 2 321 1.4E-84 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MIM_c11530 999a4cb82539da590b3dddf13ee2b19a 329 Hamap MF_00323 Ferrochelatase [hemH]. 1 321 34.814 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MIM_c11530 999a4cb82539da590b3dddf13ee2b19a 329 Pfam PF00762 Ferrochelatase 3 321 3.4E-105 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MIM_c06260 706ac96b94fa0b73a4f811b9c8f9bd42 819 Gene3D G3DSA:3.40.50.10540 12 354 3.0E-64 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c06260 706ac96b94fa0b73a4f811b9c8f9bd42 819 Pfam PF02515 CoA-transferase family III 409 784 2.4E-99 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 MIM_c06260 706ac96b94fa0b73a4f811b9c8f9bd42 819 Pfam PF02515 CoA-transferase family III 12 384 2.6E-55 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 MIM_c06260 706ac96b94fa0b73a4f811b9c8f9bd42 819 Gene3D G3DSA:3.40.50.10540 408 802 1.8E-110 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c06260 706ac96b94fa0b73a4f811b9c8f9bd42 819 Gene3D G3DSA:3.30.1540.10 238 330 3.0E-64 T 12-10-2018 MIM_c06260 706ac96b94fa0b73a4f811b9c8f9bd42 819 SUPERFAMILY SSF89796 407 807 2.88E-97 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c06260 706ac96b94fa0b73a4f811b9c8f9bd42 819 Gene3D G3DSA:3.30.1540.10 642 735 1.8E-110 T 12-10-2018 MIM_c06260 706ac96b94fa0b73a4f811b9c8f9bd42 819 SUPERFAMILY SSF89796 11 384 1.31E-63 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c38630 6606bfd1c387ea90a7eaeaa185c1f729 546 Gene3D G3DSA:3.30.300.30 442 545 1.5E-29 T 12-10-2018 MIM_c38630 6606bfd1c387ea90a7eaeaa185c1f729 546 Pfam PF00501 AMP-binding enzyme 39 444 1.6E-84 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MIM_c38630 6606bfd1c387ea90a7eaeaa185c1f729 546 Gene3D G3DSA:3.40.50.12780 15 441 6.6E-111 T 12-10-2018 MIM_c38630 6606bfd1c387ea90a7eaeaa185c1f729 546 Pfam PF13193 AMP-binding enzyme C-terminal domain 455 532 1.1E-20 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MIM_c38630 6606bfd1c387ea90a7eaeaa185c1f729 546 ProSitePatterns PS00455 Putative AMP-binding domain signature. 194 205 - T 12-10-2018 IPR020845 AMP-binding, conserved site MIM_c38630 6606bfd1c387ea90a7eaeaa185c1f729 546 SUPERFAMILY SSF56801 12 542 2.49E-141 T 12-10-2018 MIM_c36820 84a7ccb14228f14139d2eb35485201e5 208 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 13 208 5.1E-78 T 12-10-2018 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent MIM_c36820 84a7ccb14228f14139d2eb35485201e5 208 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 35 123 6.7E-14 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MIM_c36820 84a7ccb14228f14139d2eb35485201e5 208 Gene3D G3DSA:2.30.110.10 34 160 4.8E-21 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MIM_c36820 84a7ccb14228f14139d2eb35485201e5 208 SUPERFAMILY SSF50475 30 177 7.2E-19 T 12-10-2018 MIM_c31310 dd3e5d894b6adcc625cfed68237719f4 103 Pfam PF10048 Predicted integral membrane protein (DUF2282) 42 93 7.0E-24 T 12-10-2018 IPR018740 Protein of unknown function DUF2282, integral membrane MIM_c38370 7560fae5cf105695034697f32452654a 264 Pfam PF01613 Flavin reductase like domain 114 257 2.1E-24 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MIM_c38370 7560fae5cf105695034697f32452654a 264 Gene3D G3DSA:2.30.110.10 90 262 9.4E-36 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MIM_c38370 7560fae5cf105695034697f32452654a 264 SUPERFAMILY SSF50475 109 261 5.89E-34 T 12-10-2018 MIM_c38370 7560fae5cf105695034697f32452654a 264 SMART SM00903 114 258 3.1E-31 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MIM_c09820 b6af2da9ded736c6850cfc8544b8a10b 307 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 3 296 3.7E-115 T 12-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 MIM_c09820 b6af2da9ded736c6850cfc8544b8a10b 307 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 2 283 44.808 T 12-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 MIM_c09820 b6af2da9ded736c6850cfc8544b8a10b 307 Gene3D G3DSA:3.30.230.20 1 127 4.2E-48 T 12-10-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 MIM_c09820 b6af2da9ded736c6850cfc8544b8a10b 307 SUPERFAMILY SSF54211 3 125 1.59E-41 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MIM_c09820 b6af2da9ded736c6850cfc8544b8a10b 307 SUPERFAMILY SSF54211 143 282 2.2E-49 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MIM_c09820 b6af2da9ded736c6850cfc8544b8a10b 307 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 4 279 7.4E-106 T 12-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 MIM_c09820 b6af2da9ded736c6850cfc8544b8a10b 307 Gene3D G3DSA:3.30.1700.10 128 305 3.9E-63 T 12-10-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 MIM_c00980 20c5f957b02f27757a08edd6fa680b5f 241 SMART SM00345 15 73 2.9E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c00980 20c5f957b02f27757a08edd6fa680b5f 241 SUPERFAMILY SSF48008 80 219 9.68E-21 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c00980 20c5f957b02f27757a08edd6fa680b5f 241 SMART SM00895 83 213 1.0E-4 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c00980 20c5f957b02f27757a08edd6fa680b5f 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 73 3.0E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c00980 20c5f957b02f27757a08edd6fa680b5f 241 Gene3D G3DSA:1.20.120.530 77 225 1.6E-19 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c00980 20c5f957b02f27757a08edd6fa680b5f 241 SUPERFAMILY SSF46785 5 77 2.06E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c00980 20c5f957b02f27757a08edd6fa680b5f 241 Pfam PF07729 FCD domain 83 212 4.9E-16 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c00980 20c5f957b02f27757a08edd6fa680b5f 241 Gene3D G3DSA:1.10.10.10 2 74 1.2E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c07860 ae3da066a5fa480df61d735170bb49af 323 SUPERFAMILY SSF53850 100 287 3.47E-9 T 12-10-2018 MIM_c07860 ae3da066a5fa480df61d735170bb49af 323 Gene3D G3DSA:3.40.190.150 29 313 8.7E-108 T 12-10-2018 MIM_c07860 ae3da066a5fa480df61d735170bb49af 323 Gene3D G3DSA:3.40.190.10 127 248 8.7E-108 T 12-10-2018 MIM_c07860 ae3da066a5fa480df61d735170bb49af 323 PIRSF PIRSF017082 1 323 1.1E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c07860 ae3da066a5fa480df61d735170bb49af 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 319 1.5E-80 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c25050 8e8a0b362dea26ec3ea77367b8032662 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 3.3E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c25050 8e8a0b362dea26ec3ea77367b8032662 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 3.3E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c25050 8e8a0b362dea26ec3ea77367b8032662 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.3E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c25050 8e8a0b362dea26ec3ea77367b8032662 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 3.3E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c25050 8e8a0b362dea26ec3ea77367b8032662 232 SUPERFAMILY SSF51735 4 220 6.62E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c25050 8e8a0b362dea26ec3ea77367b8032662 232 Gene3D G3DSA:3.40.50.720 2 231 5.6E-46 T 12-10-2018 MIM_c25050 8e8a0b362dea26ec3ea77367b8032662 232 Pfam PF00106 short chain dehydrogenase 5 174 1.4E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c31060 1a457f632b58a96ddc02501ddb1524b7 289 SUPERFAMILY SSF53474 6 277 2.53E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c31060 1a457f632b58a96ddc02501ddb1524b7 289 Pfam PF00561 alpha/beta hydrolase fold 34 145 1.5E-16 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c31060 1a457f632b58a96ddc02501ddb1524b7 289 Gene3D G3DSA:3.40.50.1820 18 283 3.1E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c31060 1a457f632b58a96ddc02501ddb1524b7 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 124 137 4.9E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c31060 1a457f632b58a96ddc02501ddb1524b7 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 60 75 4.9E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c31060 1a457f632b58a96ddc02501ddb1524b7 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 110 123 4.9E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c26070 4f357a63fce271c6a04071d23b366d3b 154 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MIM_c26070 4f357a63fce271c6a04071d23b366d3b 154 SUPERFAMILY SSF47240 1 154 2.92E-45 T 12-10-2018 IPR009078 Ferritin-like superfamily MIM_c26070 4f357a63fce271c6a04071d23b366d3b 154 PRINTS PR00601 Bacterioferritin signature 106 126 4.8E-42 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MIM_c26070 4f357a63fce271c6a04071d23b366d3b 154 PRINTS PR00601 Bacterioferritin signature 23 43 4.8E-42 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MIM_c26070 4f357a63fce271c6a04071d23b366d3b 154 PRINTS PR00601 Bacterioferritin signature 3 22 4.8E-42 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MIM_c26070 4f357a63fce271c6a04071d23b366d3b 154 PRINTS PR00601 Bacterioferritin signature 85 105 4.8E-42 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MIM_c26070 4f357a63fce271c6a04071d23b366d3b 154 PRINTS PR00601 Bacterioferritin signature 128 149 4.8E-42 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MIM_c26070 4f357a63fce271c6a04071d23b366d3b 154 PRINTS PR00601 Bacterioferritin signature 44 64 4.8E-42 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MIM_c26070 4f357a63fce271c6a04071d23b366d3b 154 TIGRFAM TIGR00754 bfr: bacterioferritin 1 154 3.5E-48 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MIM_c26070 4f357a63fce271c6a04071d23b366d3b 154 Gene3D G3DSA:1.20.1260.10 1 154 1.6E-63 T 12-10-2018 IPR012347 Ferritin-like MIM_c26070 4f357a63fce271c6a04071d23b366d3b 154 PIRSF PIRSF002560 1 154 4.5E-63 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MIM_c26070 4f357a63fce271c6a04071d23b366d3b 154 Pfam PF00210 Ferritin-like domain 8 143 1.5E-32 T 12-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 MIM_c08790 cd2ee727a82b37735e1c526f5fdd2d7a 236 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 219 9.9E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c08790 cd2ee727a82b37735e1c526f5fdd2d7a 236 Gene3D G3DSA:1.10.3720.10 18 228 4.3E-43 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c08790 cd2ee727a82b37735e1c526f5fdd2d7a 236 SUPERFAMILY SSF161098 19 219 4.47E-37 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c08790 cd2ee727a82b37735e1c526f5fdd2d7a 236 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 19 120 5.2E-14 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c37390 217ccd4937b53166b3f9e8a3bb6037d9 149 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 32 139 6.2E-16 T 12-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 MIM_c37390 217ccd4937b53166b3f9e8a3bb6037d9 149 Pfam PF03061 Thioesterase superfamily 55 127 2.8E-10 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MIM_c37390 217ccd4937b53166b3f9e8a3bb6037d9 149 Gene3D G3DSA:3.10.129.10 5 141 9.7E-31 T 12-10-2018 MIM_c37390 217ccd4937b53166b3f9e8a3bb6037d9 149 SUPERFAMILY SSF54637 7 144 2.16E-26 T 12-10-2018 IPR029069 HotDog domain superfamily MIM_c21950 4abcff6057a5b223a229a2ca699836dd 644 Gene3D G3DSA:3.30.54.20 135 191 4.1E-66 T 12-10-2018 MIM_c21950 4abcff6057a5b223a229a2ca699836dd 644 SMART SM00863 174 223 8.0E-25 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 MIM_c21950 4abcff6057a5b223a229a2ca699836dd 644 PRINTS PR01047 Threonyl-tRNA synthetase signature 366 389 1.8E-52 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MIM_c21950 4abcff6057a5b223a229a2ca699836dd 644 PRINTS PR01047 Threonyl-tRNA synthetase signature 538 550 1.8E-52 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MIM_c21950 4abcff6057a5b223a229a2ca699836dd 644 PRINTS PR01047 Threonyl-tRNA synthetase signature 511 524 1.8E-52 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MIM_c21950 4abcff6057a5b223a229a2ca699836dd 644 PRINTS PR01047 Threonyl-tRNA synthetase signature 333 361 1.8E-52 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MIM_c21950 4abcff6057a5b223a229a2ca699836dd 644 PRINTS PR01047 Threonyl-tRNA synthetase signature 468 496 1.8E-52 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MIM_c21950 4abcff6057a5b223a229a2ca699836dd 644 Gene3D G3DSA:3.10.20.30 1 67 3.2E-16 T 12-10-2018 IPR012675 Beta-grasp domain superfamily MIM_c21950 4abcff6057a5b223a229a2ca699836dd 644 Gene3D G3DSA:3.30.930.10 227 535 2.7E-124 T 12-10-2018 MIM_c21950 4abcff6057a5b223a229a2ca699836dd 644 SUPERFAMILY SSF81271 3 66 2.35E-8 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MIM_c21950 4abcff6057a5b223a229a2ca699836dd 644 Pfam PF02824 TGS domain 3 66 9.9E-5 T 12-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 MIM_c21950 4abcff6057a5b223a229a2ca699836dd 644 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 77 635 1.1E-217 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MIM_c21950 4abcff6057a5b223a229a2ca699836dd 644 SUPERFAMILY SSF52954 534 636 7.4E-30 T 12-10-2018 MIM_c21950 4abcff6057a5b223a229a2ca699836dd 644 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 71 638 34.082 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MIM_c21950 4abcff6057a5b223a229a2ca699836dd 644 Pfam PF03129 Anticodon binding domain 545 633 2.8E-19 T 12-10-2018 IPR004154 Anticodon-binding MIM_c21950 4abcff6057a5b223a229a2ca699836dd 644 Gene3D G3DSA:3.40.50.800 536 643 1.6E-29 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily MIM_c21950 4abcff6057a5b223a229a2ca699836dd 644 Gene3D G3DSA:3.30.980.10 74 226 4.1E-66 T 12-10-2018 MIM_c21950 4abcff6057a5b223a229a2ca699836dd 644 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 174 223 1.5E-14 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 MIM_c21950 4abcff6057a5b223a229a2ca699836dd 644 SUPERFAMILY SSF55681 247 530 2.87E-98 T 12-10-2018 MIM_c21950 4abcff6057a5b223a229a2ca699836dd 644 SUPERFAMILY SSF55186 69 245 2.62E-66 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 MIM_c21950 4abcff6057a5b223a229a2ca699836dd 644 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 322 533 1.5E-40 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c06130 232d3ca40989789b7606b0af3ed020c0 276 Pfam PF00005 ABC transporter 41 197 2.1E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c06130 232d3ca40989789b7606b0af3ed020c0 276 Gene3D G3DSA:3.40.50.300 23 276 5.3E-66 T 12-10-2018 MIM_c06130 232d3ca40989789b7606b0af3ed020c0 276 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c06130 232d3ca40989789b7606b0af3ed020c0 276 PIRSF PIRSF037116 13 276 2.2E-139 T 12-10-2018 IPR012700 Phosphonate C-P lyase system, PhnK MIM_c06130 232d3ca40989789b7606b0af3ed020c0 276 TIGRFAM TIGR02323 CP_lyasePhnK: phosphonate C-P lyase system protein PhnK 22 274 9.4E-115 T 12-10-2018 IPR012700 Phosphonate C-P lyase system, PhnK MIM_c06130 232d3ca40989789b7606b0af3ed020c0 276 SUPERFAMILY SSF52540 19 272 2.85E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c06130 232d3ca40989789b7606b0af3ed020c0 276 SMART SM00382 49 247 2.3E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c03780 84cc9d2e478e7a55b84c1632c0a87cb6 569 Gene3D G3DSA:1.10.3720.10 17 281 6.4E-49 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c03780 84cc9d2e478e7a55b84c1632c0a87cb6 569 Gene3D G3DSA:1.10.3720.10 300 560 5.7E-42 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c03780 84cc9d2e478e7a55b84c1632c0a87cb6 569 SUPERFAMILY SSF161098 16 279 1.57E-42 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c03780 84cc9d2e478e7a55b84c1632c0a87cb6 569 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 385 563 9.1E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c03780 84cc9d2e478e7a55b84c1632c0a87cb6 569 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 281 2.0E-13 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c03780 84cc9d2e478e7a55b84c1632c0a87cb6 569 SUPERFAMILY SSF161098 299 558 1.96E-46 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c36610 bd0c9ccc1fb10af7409117add011c3c7 266 Gene3D G3DSA:1.10.10.10 19 88 8.5E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c36610 bd0c9ccc1fb10af7409117add011c3c7 266 Gene3D G3DSA:3.30.450.40 91 262 4.3E-51 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c36610 bd0c9ccc1fb10af7409117add011c3c7 266 SMART SM00346 16 106 2.8E-5 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c36610 bd0c9ccc1fb10af7409117add011c3c7 266 Pfam PF09339 IclR helix-turn-helix domain 21 68 1.1E-9 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c36610 bd0c9ccc1fb10af7409117add011c3c7 266 SUPERFAMILY SSF46785 20 85 1.13E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c36610 bd0c9ccc1fb10af7409117add011c3c7 266 SUPERFAMILY SSF55781 94 257 9.16E-47 T 12-10-2018 MIM_c36610 bd0c9ccc1fb10af7409117add011c3c7 266 Pfam PF01614 Bacterial transcriptional regulator 134 256 4.1E-32 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal MIM_c33190 7e8f3f6e6d8d522cbe7c9ece9bfe16ca 334 PIRSF PIRSF017082 9 333 4.9E-73 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c33190 7e8f3f6e6d8d522cbe7c9ece9bfe16ca 334 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 58 330 2.0E-71 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c33190 7e8f3f6e6d8d522cbe7c9ece9bfe16ca 334 SUPERFAMILY SSF53850 126 299 1.9E-11 T 12-10-2018 MIM_c33190 7e8f3f6e6d8d522cbe7c9ece9bfe16ca 334 Gene3D G3DSA:3.40.190.10 137 259 1.6E-94 T 12-10-2018 MIM_c33190 7e8f3f6e6d8d522cbe7c9ece9bfe16ca 334 Gene3D G3DSA:3.40.190.150 39 323 1.6E-94 T 12-10-2018 MIM_c22890 cc20fc95d60f9dec96acd5cf731cdd0a 227 SUPERFAMILY SSF56784 1 204 3.81E-50 T 12-10-2018 IPR036412 HAD-like superfamily MIM_c22890 cc20fc95d60f9dec96acd5cf731cdd0a 227 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 72 183 6.7E-11 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MIM_c22890 cc20fc95d60f9dec96acd5cf731cdd0a 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 184 2.9E-30 T 12-10-2018 MIM_c22890 cc20fc95d60f9dec96acd5cf731cdd0a 227 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 5 193 7.6E-52 T 12-10-2018 IPR006346 2-phosphoglycolate phosphatase-like, prokaryotic GO:0016791 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 MIM_c22890 cc20fc95d60f9dec96acd5cf731cdd0a 227 Gene3D G3DSA:3.40.50.1000 5 189 2.5E-50 T 12-10-2018 IPR023214 HAD superfamily MIM_c22890 cc20fc95d60f9dec96acd5cf731cdd0a 227 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 92 179 1.1E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MIM_c22890 cc20fc95d60f9dec96acd5cf731cdd0a 227 Gene3D G3DSA:1.10.150.240 17 84 2.5E-50 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MIM_c34960 4dfac4cc285500948904af410d9cab15 349 Gene3D G3DSA:3.40.50.720 1 210 8.6E-54 T 12-10-2018 MIM_c34960 4dfac4cc285500948904af410d9cab15 349 Gene3D G3DSA:1.10.1040.10 211 347 1.8E-33 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MIM_c34960 4dfac4cc285500948904af410d9cab15 349 Pfam PF02558 Ketopantoate reductase PanE/ApbA 4 180 5.7E-22 T 12-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain MIM_c34960 4dfac4cc285500948904af410d9cab15 349 SUPERFAMILY SSF51735 1 109 1.18E-6 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c34960 4dfac4cc285500948904af410d9cab15 349 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 211 333 4.1E-27 T 12-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain MIM_c34960 4dfac4cc285500948904af410d9cab15 349 SUPERFAMILY SSF48179 211 334 1.02E-28 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c14250 196957ffffcf6fe0994326c61663ffdd 677 Gene3D G3DSA:3.40.50.300 350 522 5.8E-59 T 12-10-2018 MIM_c14250 196957ffffcf6fe0994326c61663ffdd 677 Pfam PF02954 Bacterial regulatory protein, Fis family 624 663 4.4E-12 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MIM_c14250 196957ffffcf6fe0994326c61663ffdd 677 Gene3D G3DSA:3.30.450.40 20 206 2.5E-46 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c14250 196957ffffcf6fe0994326c61663ffdd 677 Pfam PF01590 GAF domain 93 204 1.0E-7 T 12-10-2018 IPR003018 GAF domain GO:0005515 MIM_c14250 196957ffffcf6fe0994326c61663ffdd 677 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 630 647 3.2E-6 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MIM_c14250 196957ffffcf6fe0994326c61663ffdd 677 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 647 667 3.2E-6 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MIM_c14250 196957ffffcf6fe0994326c61663ffdd 677 SUPERFAMILY SSF55781 69 189 6.67E-5 T 12-10-2018 MIM_c14250 196957ffffcf6fe0994326c61663ffdd 677 Pfam PF00158 Sigma-54 interaction domain 357 517 1.4E-61 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MIM_c14250 196957ffffcf6fe0994326c61663ffdd 677 SUPERFAMILY SSF52540 357 588 7.22E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c14250 196957ffffcf6fe0994326c61663ffdd 677 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 374 387 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MIM_c14250 196957ffffcf6fe0994326c61663ffdd 677 Gene3D G3DSA:1.10.10.60 620 669 1.8E-13 T 12-10-2018 MIM_c14250 196957ffffcf6fe0994326c61663ffdd 677 SUPERFAMILY SSF46689 559 666 3.39E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c14250 196957ffffcf6fe0994326c61663ffdd 677 Gene3D G3DSA:1.10.8.60 523 597 4.5E-12 T 12-10-2018 MIM_c14250 196957ffffcf6fe0994326c61663ffdd 677 SMART SM00382 370 514 3.2E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c14250 196957ffffcf6fe0994326c61663ffdd 677 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 437 452 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MIM_c35470 8bcc32580818a7b242fb98a265de4e85 330 Gene3D G3DSA:3.40.50.300 6 329 7.3E-98 T 12-10-2018 MIM_c35470 8bcc32580818a7b242fb98a265de4e85 330 Pfam PF00005 ABC transporter 29 188 1.9E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c35470 8bcc32580818a7b242fb98a265de4e85 330 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 238 323 5.0E-27 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c35470 8bcc32580818a7b242fb98a265de4e85 330 SUPERFAMILY SSF52540 8 260 2.55E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c35470 8bcc32580818a7b242fb98a265de4e85 330 SMART SM00382 37 240 1.0E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c35470 8bcc32580818a7b242fb98a265de4e85 330 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 240 304 2.8E-20 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c40310 70b035665d4c4d3f6d4a54f1992c001f 322 PIRSF PIRSF000105 4 312 6.4E-66 T 12-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 MIM_c40310 70b035665d4c4d3f6d4a54f1992c001f 322 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 186 210 - T 12-10-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MIM_c40310 70b035665d4c4d3f6d4a54f1992c001f 322 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 189 256 2.2E-16 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MIM_c40310 70b035665d4c4d3f6d4a54f1992c001f 322 SUPERFAMILY SSF48179 189 261 1.87E-14 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c40310 70b035665d4c4d3f6d4a54f1992c001f 322 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 9 185 1.5E-45 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MIM_c40310 70b035665d4c4d3f6d4a54f1992c001f 322 SUPERFAMILY SSF51735 8 183 2.66E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c40310 70b035665d4c4d3f6d4a54f1992c001f 322 Gene3D G3DSA:3.40.50.720 6 189 7.4E-50 T 12-10-2018 MIM_c40310 70b035665d4c4d3f6d4a54f1992c001f 322 Gene3D G3DSA:1.10.1040.10 190 314 9.1E-46 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MIM_c26610 c6f35ecde47590354bc8f41b2d09f43f 711 SUPERFAMILY SSF109604 355 500 1.26E-9 T 12-10-2018 MIM_c26610 c6f35ecde47590354bc8f41b2d09f43f 711 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 330 346 1.2E-31 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MIM_c26610 c6f35ecde47590354bc8f41b2d09f43f 711 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 51 63 1.2E-31 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MIM_c26610 c6f35ecde47590354bc8f41b2d09f43f 711 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 6 19 1.2E-31 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MIM_c26610 c6f35ecde47590354bc8f41b2d09f43f 711 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 257 272 1.2E-31 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MIM_c26610 c6f35ecde47590354bc8f41b2d09f43f 711 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 406 425 1.2E-31 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MIM_c26610 c6f35ecde47590354bc8f41b2d09f43f 711 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 2 709 22.412 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MIM_c26610 c6f35ecde47590354bc8f41b2d09f43f 711 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 5 574 1.1E-182 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MIM_c26610 c6f35ecde47590354bc8f41b2d09f43f 711 Pfam PF05746 DALR anticodon binding domain 604 701 2.0E-7 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MIM_c26610 c6f35ecde47590354bc8f41b2d09f43f 711 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 5 709 6.8E-175 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MIM_c22960 351650a6789a13e55513a910b7087b8f 736 Gene3D G3DSA:3.90.226.10 360 600 7.6E-56 T 12-10-2018 MIM_c22960 351650a6789a13e55513a910b7087b8f 736 SMART SM00245 362 582 5.5E-45 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 MIM_c22960 351650a6789a13e55513a910b7087b8f 736 Gene3D G3DSA:2.30.42.10 268 354 1.0E-13 T 12-10-2018 MIM_c22960 351650a6789a13e55513a910b7087b8f 736 Pfam PF11818 C-terminal domain of tail specific protease (DUF3340) 585 733 4.3E-32 T 12-10-2018 IPR020992 Tail specific protease, C-terminal MIM_c22960 351650a6789a13e55513a910b7087b8f 736 SUPERFAMILY SSF52096 198 586 6.63E-60 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c22960 351650a6789a13e55513a910b7087b8f 736 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 275 353 7.7E-13 T 12-10-2018 IPR001478 PDZ domain GO:0005515 MIM_c22960 351650a6789a13e55513a910b7087b8f 736 SMART SM00228 279 357 3.3E-9 T 12-10-2018 IPR001478 PDZ domain GO:0005515 MIM_c22960 351650a6789a13e55513a910b7087b8f 736 Pfam PF03572 Peptidase family S41 396 580 7.8E-44 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 MIM_c22960 351650a6789a13e55513a910b7087b8f 736 SUPERFAMILY SSF50156 278 352 8.05E-12 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 MIM_c22960 351650a6789a13e55513a910b7087b8f 736 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 239 601 8.6E-86 T 12-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 MIM_c37890 e53f346b62883a789476769c79d3c34a 353 Gene3D G3DSA:3.40.190.10 136 333 2.6E-64 T 12-10-2018 MIM_c37890 e53f346b62883a789476769c79d3c34a 353 Pfam PF13416 Bacterial extracellular solute-binding protein 55 313 1.8E-28 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein MIM_c37890 e53f346b62883a789476769c79d3c34a 353 SUPERFAMILY SSF53850 33 349 6.96E-54 T 12-10-2018 MIM_c37890 e53f346b62883a789476769c79d3c34a 353 Gene3D G3DSA:3.40.190.10 40 318 2.6E-64 T 12-10-2018 MIM_c30110 c9fdaad0d3a4555cc9c2367024b06050 618 Gene3D G3DSA:3.60.120.10 49 400 4.9E-95 T 12-10-2018 IPR005801 ADC synthase GO:0009058 MIM_c30110 c9fdaad0d3a4555cc9c2367024b06050 618 Gene3D G3DSA:3.20.10.10 486 616 4.5E-30 T 12-10-2018 MIM_c30110 c9fdaad0d3a4555cc9c2367024b06050 618 PRINTS PR00095 Anthranilate synthase component I signature 320 334 6.6E-7 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MIM_c30110 c9fdaad0d3a4555cc9c2367024b06050 618 PRINTS PR00095 Anthranilate synthase component I signature 226 239 6.6E-7 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MIM_c30110 c9fdaad0d3a4555cc9c2367024b06050 618 PRINTS PR00095 Anthranilate synthase component I signature 240 253 6.6E-7 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MIM_c30110 c9fdaad0d3a4555cc9c2367024b06050 618 Gene3D G3DSA:3.30.470.10 401 483 4.1E-10 T 12-10-2018 MIM_c30110 c9fdaad0d3a4555cc9c2367024b06050 618 SUPERFAMILY SSF56752 343 614 1.31E-43 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 MIM_c30110 c9fdaad0d3a4555cc9c2367024b06050 618 SUPERFAMILY SSF56322 60 396 4.45E-83 T 12-10-2018 IPR005801 ADC synthase GO:0009058 MIM_c30110 c9fdaad0d3a4555cc9c2367024b06050 618 Pfam PF00425 chorismate binding enzyme 122 390 7.5E-71 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal MIM_c30110 c9fdaad0d3a4555cc9c2367024b06050 618 Pfam PF01063 Amino-transferase class IV 403 614 3.1E-35 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 MIM_c22830 16bb37b0b74d6f9333cbefb93d21ffbd 378 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 237 246 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 MIM_c22830 16bb37b0b74d6f9333cbefb93d21ffbd 378 SUPERFAMILY SSF53383 18 376 4.17E-80 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c22830 16bb37b0b74d6f9333cbefb93d21ffbd 378 Gene3D G3DSA:3.90.1150.10 35 369 2.1E-105 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c22830 16bb37b0b74d6f9333cbefb93d21ffbd 378 Pfam PF00155 Aminotransferase class I and II 40 367 1.5E-43 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MIM_c22830 16bb37b0b74d6f9333cbefb93d21ffbd 378 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 9 376 58.88 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 MIM_c22830 16bb37b0b74d6f9333cbefb93d21ffbd 378 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 13 375 1.0E-100 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 MIM_c22830 16bb37b0b74d6f9333cbefb93d21ffbd 378 Gene3D G3DSA:3.40.640.10 52 285 2.1E-105 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c34830 ca0bfb8f72db137d6f3e8c4d17328ff5 273 SMART SM00342 187 269 3.1E-26 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c34830 ca0bfb8f72db137d6f3e8c4d17328ff5 273 SUPERFAMILY SSF51215 36 153 8.37E-6 T 12-10-2018 IPR037923 Transcription regulator HTH-like MIM_c34830 ca0bfb8f72db137d6f3e8c4d17328ff5 273 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 224 265 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MIM_c34830 ca0bfb8f72db137d6f3e8c4d17328ff5 273 Pfam PF12852 Cupin 3 156 8.8E-25 T 12-10-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain MIM_c34830 ca0bfb8f72db137d6f3e8c4d17328ff5 273 Gene3D G3DSA:1.10.10.60 169 222 2.3E-11 T 12-10-2018 MIM_c34830 ca0bfb8f72db137d6f3e8c4d17328ff5 273 Gene3D G3DSA:1.10.10.60 223 271 2.6E-9 T 12-10-2018 MIM_c34830 ca0bfb8f72db137d6f3e8c4d17328ff5 273 SUPERFAMILY SSF46689 170 221 8.51E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c34830 ca0bfb8f72db137d6f3e8c4d17328ff5 273 SUPERFAMILY SSF46689 223 271 6.27E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c34830 ca0bfb8f72db137d6f3e8c4d17328ff5 273 Pfam PF12833 Helix-turn-helix domain 193 269 5.6E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c36050 64b4b5219f0e8b395cd6e8b38350730b 338 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 113 288 1.4E-51 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MIM_c36050 64b4b5219f0e8b395cd6e8b38350730b 338 SUPERFAMILY SSF52283 13 138 2.27E-29 T 12-10-2018 MIM_c36050 64b4b5219f0e8b395cd6e8b38350730b 338 Gene3D G3DSA:3.40.50.720 15 312 1.4E-89 T 12-10-2018 MIM_c36050 64b4b5219f0e8b395cd6e8b38350730b 338 Gene3D G3DSA:3.40.50.720 104 286 1.4E-89 T 12-10-2018 MIM_c36050 64b4b5219f0e8b395cd6e8b38350730b 338 SUPERFAMILY SSF51735 104 289 8.91E-51 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c36050 64b4b5219f0e8b395cd6e8b38350730b 338 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 14 320 4.7E-28 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 MIM_c12310 56594a0ccbe1888e701d1786d01840b2 877 SMART SM00534 623 810 7.8E-107 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MIM_c12310 56594a0ccbe1888e701d1786d01840b2 877 SUPERFAMILY SSF48334 274 581 4.58E-82 T 12-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily MIM_c12310 56594a0ccbe1888e701d1786d01840b2 877 Pfam PF05188 MutS domain II 145 260 1.9E-20 T 12-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 MIM_c12310 56594a0ccbe1888e701d1786d01840b2 877 SMART SM00533 290 608 6.5E-85 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 MIM_c12310 56594a0ccbe1888e701d1786d01840b2 877 PIRSF PIRSF037677 5 864 8.7E-149 T 12-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 MIM_c12310 56594a0ccbe1888e701d1786d01840b2 877 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 13 865 24.303 T 12-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 MIM_c12310 56594a0ccbe1888e701d1786d01840b2 877 Pfam PF05192 MutS domain III 277 576 1.8E-38 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 MIM_c12310 56594a0ccbe1888e701d1786d01840b2 877 Gene3D G3DSA:1.10.1420.10 407 552 2.2E-95 T 12-10-2018 MIM_c12310 56594a0ccbe1888e701d1786d01840b2 877 Pfam PF00488 MutS domain V 627 813 9.3E-80 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MIM_c12310 56594a0ccbe1888e701d1786d01840b2 877 Gene3D G3DSA:3.40.1170.10 5 127 3.5E-49 T 12-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 MIM_c12310 56594a0ccbe1888e701d1786d01840b2 877 Gene3D G3DSA:1.10.1420.10 273 576 2.2E-95 T 12-10-2018 MIM_c12310 56594a0ccbe1888e701d1786d01840b2 877 SUPERFAMILY SSF52540 584 814 5.03E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c12310 56594a0ccbe1888e701d1786d01840b2 877 Pfam PF05190 MutS family domain IV 445 535 4.1E-28 T 12-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 MIM_c12310 56594a0ccbe1888e701d1786d01840b2 877 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 704 720 - T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MIM_c12310 56594a0ccbe1888e701d1786d01840b2 877 SUPERFAMILY SSF53150 123 287 3.01E-35 T 12-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 MIM_c12310 56594a0ccbe1888e701d1786d01840b2 877 Gene3D G3DSA:3.40.50.300 585 874 2.9E-94 T 12-10-2018 MIM_c12310 56594a0ccbe1888e701d1786d01840b2 877 Gene3D G3DSA:3.30.420.110 136 267 6.6E-31 T 12-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 MIM_c12310 56594a0ccbe1888e701d1786d01840b2 877 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 13 870 0.0 T 12-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 MIM_c12310 56594a0ccbe1888e701d1786d01840b2 877 SUPERFAMILY SSF55271 9 119 1.44E-41 T 12-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 MIM_c12310 56594a0ccbe1888e701d1786d01840b2 877 Pfam PF01624 MutS domain I 14 125 1.1E-40 T 12-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 MIM_c05580 dd92531b0047eb5cca3efd30dda8a3de 198 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 29 181 4.5E-43 T 12-10-2018 IPR010023 KdsC family GO:0016788 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MIM_c05580 dd92531b0047eb5cca3efd30dda8a3de 198 PIRSF PIRSF006118 16 188 5.3E-59 T 12-10-2018 IPR010023 KdsC family GO:0016788 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MIM_c05580 dd92531b0047eb5cca3efd30dda8a3de 198 Pfam PF08282 haloacid dehalogenase-like hydrolase 96 161 1.7E-6 T 12-10-2018 MIM_c05580 dd92531b0047eb5cca3efd30dda8a3de 198 SUPERFAMILY SSF56784 27 183 1.84E-38 T 12-10-2018 IPR036412 HAD-like superfamily MIM_c05580 dd92531b0047eb5cca3efd30dda8a3de 198 Gene3D G3DSA:3.40.50.1000 9 187 1.4E-47 T 12-10-2018 IPR023214 HAD superfamily MIM_c38940 5f6349754bfe2bdfb825443ad5221115 327 SUPERFAMILY SSF55257 4 228 3.66E-32 T 12-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c38940 5f6349754bfe2bdfb825443ad5221115 327 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 223 7.1E-23 T 12-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c38940 5f6349754bfe2bdfb825443ad5221115 327 SMART SM00662 20 230 2.7E-94 T 12-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c38940 5f6349754bfe2bdfb825443ad5221115 327 Gene3D G3DSA:2.170.120.12 50 173 8.8E-84 T 12-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c38940 5f6349754bfe2bdfb825443ad5221115 327 SUPERFAMILY SSF56553 50 174 4.84E-42 T 12-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c38940 5f6349754bfe2bdfb825443ad5221115 327 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 315 35.722 T 12-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c38940 5f6349754bfe2bdfb825443ad5221115 327 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 254 324 2.0E-34 T 12-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c38940 5f6349754bfe2bdfb825443ad5221115 327 SUPERFAMILY SSF47789 249 321 2.09E-26 T 12-10-2018 MIM_c38940 5f6349754bfe2bdfb825443ad5221115 327 Gene3D G3DSA:3.30.1360.10 16 223 8.8E-84 T 12-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c38940 5f6349754bfe2bdfb825443ad5221115 327 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 59 149 5.7E-23 T 12-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c38940 5f6349754bfe2bdfb825443ad5221115 327 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 21 314 6.3E-108 T 12-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c38940 5f6349754bfe2bdfb825443ad5221115 327 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 249 306 1.1E-24 T 12-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c38940 5f6349754bfe2bdfb825443ad5221115 327 Gene3D G3DSA:1.10.150.20 243 326 3.3E-36 T 12-10-2018 MIM_c18360 4a575037c5393283b9ede3281033b62a 177 SUPERFAMILY SSF50324 3 175 2.22E-65 T 12-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MIM_c18360 4a575037c5393283b9ede3281033b62a 177 Gene3D G3DSA:3.90.80.10 1 175 1.0E-68 T 12-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MIM_c18360 4a575037c5393283b9ede3281033b62a 177 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MIM_c18360 4a575037c5393283b9ede3281033b62a 177 Pfam PF00719 Inorganic pyrophosphatase 18 173 3.5E-52 T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MIM_c18360 4a575037c5393283b9ede3281033b62a 177 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 174 35.85 T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MIM_c32360 ab7f4d23f5ee421146f7dd8d19aa75cf 289 Pfam PF01618 MotA/TolQ/ExbB proton channel family 150 253 4.8E-35 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel MIM_c32360 ab7f4d23f5ee421146f7dd8d19aa75cf 289 TIGRFAM TIGR02797 exbB: tonB-system energizer ExbB 56 265 2.6E-69 T 12-10-2018 IPR014164 TonB-system energizer ExbB type-1 GO:0016020|GO:0022857|GO:0055085 MIM_c06520 0fa69305e69f39df0c3e868931b49f0c 437 Pfam PF00691 OmpA family 308 406 2.7E-17 T 12-10-2018 IPR006665 OmpA-like domain MIM_c06520 0fa69305e69f39df0c3e868931b49f0c 437 TIGRFAM TIGR03349 IV_VI_DotU: type IV/VI secretion system protein, DotU family 36 245 1.9E-73 T 12-10-2018 IPR017732 Type IV / VI secretion system, DotU MIM_c06520 0fa69305e69f39df0c3e868931b49f0c 437 SUPERFAMILY SSF103088 298 412 1.06E-27 T 12-10-2018 IPR036737 OmpA-like domain superfamily MIM_c06520 0fa69305e69f39df0c3e868931b49f0c 437 TIGRFAM TIGR03350 type_VI_ompA: type VI secretion system peptidoglycan-associated domain 276 411 1.9E-51 T 12-10-2018 IPR017733 Type VI secretion system peptidoglycan-associated domain MIM_c06520 0fa69305e69f39df0c3e868931b49f0c 437 Gene3D G3DSA:1.25.40.590 34 191 2.6E-59 T 12-10-2018 IPR038522 Type IV / VI secretion system, DotU superfamily MIM_c06520 0fa69305e69f39df0c3e868931b49f0c 437 Pfam PF09850 Type VI secretion system protein DotU 38 239 4.9E-74 T 12-10-2018 IPR017732 Type IV / VI secretion system, DotU MIM_c06520 0fa69305e69f39df0c3e868931b49f0c 437 Gene3D G3DSA:3.30.1330.60 265 415 5.7E-46 T 12-10-2018 IPR036737 OmpA-like domain superfamily MIM_c26490 dace2e82db464af54ceeadc7bf29c13c 241 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 176 3.8E-23 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c26490 dace2e82db464af54ceeadc7bf29c13c 241 Gene3D G3DSA:3.90.226.10 1 241 8.1E-64 T 12-10-2018 MIM_c26490 dace2e82db464af54ceeadc7bf29c13c 241 SUPERFAMILY SSF52096 2 215 3.25E-38 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c20110 85efb31ba0e761998ce39d99deec9d4b 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.0E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c20110 85efb31ba0e761998ce39d99deec9d4b 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.0E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c20110 85efb31ba0e761998ce39d99deec9d4b 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.0E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c20110 85efb31ba0e761998ce39d99deec9d4b 310 Gene3D G3DSA:3.40.190.10 101 305 7.6E-40 T 12-10-2018 MIM_c20110 85efb31ba0e761998ce39d99deec9d4b 310 SUPERFAMILY SSF46785 1 86 9.37E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c20110 85efb31ba0e761998ce39d99deec9d4b 310 Gene3D G3DSA:3.40.190.10 180 284 7.6E-40 T 12-10-2018 MIM_c20110 85efb31ba0e761998ce39d99deec9d4b 310 Gene3D G3DSA:1.10.10.10 1 92 5.1E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c20110 85efb31ba0e761998ce39d99deec9d4b 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.9E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c20110 85efb31ba0e761998ce39d99deec9d4b 310 SUPERFAMILY SSF53850 99 308 1.54E-26 T 12-10-2018 MIM_c20110 85efb31ba0e761998ce39d99deec9d4b 310 Pfam PF03466 LysR substrate binding domain 104 307 4.1E-24 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_24p00120 7716055b49696dd507441d4293273325 346 Gene3D G3DSA:3.30.420.10 162 329 9.7E-15 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MIM_24p00120 7716055b49696dd507441d4293273325 346 SUPERFAMILY SSF53098 160 336 9.23E-38 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily MIM_24p00120 7716055b49696dd507441d4293273325 346 Pfam PF13551 Winged helix-turn helix 11 74 5.7E-17 T 12-10-2018 MIM_24p00120 7716055b49696dd507441d4293273325 346 Pfam PF00665 Integrase core domain 161 284 8.8E-20 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 MIM_24p00120 7716055b49696dd507441d4293273325 346 SUPERFAMILY SSF46689 16 113 1.65E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_24p00160 7716055b49696dd507441d4293273325 346 Gene3D G3DSA:3.30.420.10 162 329 9.7E-15 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MIM_24p00160 7716055b49696dd507441d4293273325 346 SUPERFAMILY SSF53098 160 336 9.23E-38 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily MIM_24p00160 7716055b49696dd507441d4293273325 346 Pfam PF13551 Winged helix-turn helix 11 74 5.7E-17 T 12-10-2018 MIM_24p00160 7716055b49696dd507441d4293273325 346 Pfam PF00665 Integrase core domain 161 284 8.8E-20 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 MIM_24p00160 7716055b49696dd507441d4293273325 346 SUPERFAMILY SSF46689 16 113 1.65E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c18430 cef9f4ac5123fc6759345ab407334ac1 775 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 18 758 6.2E-228 T 12-10-2018 MIM_c18430 cef9f4ac5123fc6759345ab407334ac1 775 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 13 768 32.782 T 12-10-2018 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MIM_c18430 cef9f4ac5123fc6759345ab407334ac1 775 Gene3D G3DSA:3.30.1360.40 246 362 1.2E-182 T 12-10-2018 MIM_c18430 cef9f4ac5123fc6759345ab407334ac1 775 SUPERFAMILY SSF56719 40 514 1.06E-144 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MIM_c18430 cef9f4ac5123fc6759345ab407334ac1 775 Gene3D G3DSA:2.120.10.90 527 756 1.6E-19 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal MIM_c18430 cef9f4ac5123fc6759345ab407334ac1 775 Gene3D G3DSA:3.90.199.10 41 514 1.2E-182 T 12-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 MIM_c18430 cef9f4ac5123fc6759345ab407334ac1 775 Gene3D G3DSA:1.10.268.10 400 485 1.2E-182 T 12-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MIM_c18430 cef9f4ac5123fc6759345ab407334ac1 775 SMART SM00434 20 492 1.5E-210 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MIM_c18430 cef9f4ac5123fc6759345ab407334ac1 775 SUPERFAMILY SSF101904 529 763 8.11E-43 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal MIM_c18430 cef9f4ac5123fc6759345ab407334ac1 775 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 41 498 2.0E-124 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MIM_c19650 cbbc66576d942fe591c73821e78d68d5 433 SUPERFAMILY SSF51735 198 432 3.31E-74 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c19650 cbbc66576d942fe591c73821e78d68d5 433 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 117 130 - T 12-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MIM_c19650 cbbc66576d942fe591c73821e78d68d5 433 Gene3D G3DSA:3.40.50.10860 61 197 2.1E-57 T 12-10-2018 MIM_c19650 cbbc66576d942fe591c73821e78d68d5 433 SMART SM00839 200 430 9.1E-90 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MIM_c19650 cbbc66576d942fe591c73821e78d68d5 433 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 198 430 2.0E-74 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MIM_c19650 cbbc66576d942fe591c73821e78d68d5 433 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 52 180 1.2E-54 T 12-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MIM_c19650 cbbc66576d942fe591c73821e78d68d5 433 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 109 123 2.8E-33 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MIM_c19650 cbbc66576d942fe591c73821e78d68d5 433 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 231 251 2.8E-33 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MIM_c19650 cbbc66576d942fe591c73821e78d68d5 433 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 358 369 2.8E-33 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MIM_c19650 cbbc66576d942fe591c73821e78d68d5 433 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 189 211 2.8E-33 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MIM_c19650 cbbc66576d942fe591c73821e78d68d5 433 Gene3D G3DSA:1.10.8.1210 1 60 3.0E-23 T 12-10-2018 MIM_c19650 cbbc66576d942fe591c73821e78d68d5 433 Gene3D G3DSA:3.40.50.720 198 433 5.9E-83 T 12-10-2018 MIM_c19650 cbbc66576d942fe591c73821e78d68d5 433 SUPERFAMILY SSF53223 16 200 2.14E-67 T 12-10-2018 MIM_c19650 cbbc66576d942fe591c73821e78d68d5 433 PIRSF PIRSF000185 23 433 5.7E-158 T 12-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 MIM_c29990 2891a116f465edf72f8d6cc9c1e46342 160 SUPERFAMILY SSF103088 50 156 1.24E-32 T 12-10-2018 IPR036737 OmpA-like domain superfamily MIM_c29990 2891a116f465edf72f8d6cc9c1e46342 160 Gene3D G3DSA:3.30.1330.60 40 160 1.5E-35 T 12-10-2018 IPR036737 OmpA-like domain superfamily MIM_c29990 2891a116f465edf72f8d6cc9c1e46342 160 PRINTS PR01021 OMPA domain signature 103 119 5.1E-13 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MIM_c29990 2891a116f465edf72f8d6cc9c1e46342 160 PRINTS PR01021 OMPA domain signature 88 103 5.1E-13 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MIM_c29990 2891a116f465edf72f8d6cc9c1e46342 160 PRINTS PR01021 OMPA domain signature 58 80 5.1E-13 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MIM_c29990 2891a116f465edf72f8d6cc9c1e46342 160 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 55 158 2.9E-40 T 12-10-2018 IPR014169 Peptidoglycan-associated lipoprotein, C-terminal GO:0009279 MIM_c29990 2891a116f465edf72f8d6cc9c1e46342 160 Pfam PF00691 OmpA family 57 152 3.1E-22 T 12-10-2018 IPR006665 OmpA-like domain MIM_c29990 2891a116f465edf72f8d6cc9c1e46342 160 Hamap MF_02204 Peptidoglycan-associated lipoprotein [pal]. 4 158 28.708 T 12-10-2018 IPR039001 Peptidoglycan-associated lipoprotein GO:0009279|GO:0051301 MIM_c34530 0510cac794c56d38c84522a034eda122 228 SUPERFAMILY SSF48008 83 210 1.26E-25 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c34530 0510cac794c56d38c84522a034eda122 228 Pfam PF07729 FCD domain 89 207 4.6E-24 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c34530 0510cac794c56d38c84522a034eda122 228 SMART SM00895 85 209 4.8E-18 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c34530 0510cac794c56d38c84522a034eda122 228 SMART SM00345 17 75 1.2E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c34530 0510cac794c56d38c84522a034eda122 228 SUPERFAMILY SSF46785 9 79 6.07E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c34530 0510cac794c56d38c84522a034eda122 228 Gene3D G3DSA:1.20.120.530 83 219 3.5E-24 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c34530 0510cac794c56d38c84522a034eda122 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 75 7.5E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c34530 0510cac794c56d38c84522a034eda122 228 Gene3D G3DSA:1.10.10.10 14 76 1.3E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c22210 2032f3c3ac13df564e4f0172457e83e6 935 SUPERFAMILY SSF81593 803 932 6.2E-31 T 12-10-2018 MIM_c22210 2032f3c3ac13df564e4f0172457e83e6 935 SUPERFAMILY SSF81301 6 273 3.15E-64 T 12-10-2018 MIM_c22210 2032f3c3ac13df564e4f0172457e83e6 935 Gene3D G3DSA:1.20.120.1510 446 555 4.6E-18 T 12-10-2018 MIM_c22210 2032f3c3ac13df564e4f0172457e83e6 935 SUPERFAMILY SSF81593 275 430 9.42E-35 T 12-10-2018 MIM_c22210 2032f3c3ac13df564e4f0172457e83e6 935 Gene3D G3DSA:1.20.120.330 801 934 4.2E-38 T 12-10-2018 MIM_c22210 2032f3c3ac13df564e4f0172457e83e6 935 SUPERFAMILY SSF81301 521 802 4.09E-68 T 12-10-2018 MIM_c22210 2032f3c3ac13df564e4f0172457e83e6 935 Pfam PF08335 GlnD PII-uridylyltransferase 285 429 1.2E-38 T 12-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 MIM_c22210 2032f3c3ac13df564e4f0172457e83e6 935 Pfam PF08335 GlnD PII-uridylyltransferase 814 908 8.0E-10 T 12-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 MIM_c22210 2032f3c3ac13df564e4f0172457e83e6 935 Gene3D G3DSA:3.30.460.100 556 799 1.0E-69 T 12-10-2018 MIM_c22210 2032f3c3ac13df564e4f0172457e83e6 935 Gene3D G3DSA:3.30.460.100 14 255 2.4E-59 T 12-10-2018 MIM_c22210 2032f3c3ac13df564e4f0172457e83e6 935 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 6 247 5.0E-58 T 12-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 MIM_c22210 2032f3c3ac13df564e4f0172457e83e6 935 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 547 793 3.2E-63 T 12-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 MIM_c22210 2032f3c3ac13df564e4f0172457e83e6 935 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 2 933 18.082 T 12-10-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 MIM_c22210 2032f3c3ac13df564e4f0172457e83e6 935 Gene3D G3DSA:1.20.120.330 273 432 6.1E-49 T 12-10-2018 MIM_c04820 56c7212cc8a6df4a778f9e1801f0c7de 80 SUPERFAMILY SSF82657 1 79 1.31E-29 T 12-10-2018 IPR036065 BolA-like superfamily MIM_c04820 56c7212cc8a6df4a778f9e1801f0c7de 80 Gene3D G3DSA:3.30.300.90 4 75 3.3E-30 T 12-10-2018 MIM_c04820 56c7212cc8a6df4a778f9e1801f0c7de 80 Pfam PF01722 BolA-like protein 5 75 6.3E-21 T 12-10-2018 IPR002634 BolA protein MIM_c04820 56c7212cc8a6df4a778f9e1801f0c7de 80 PIRSF PIRSF003113 1 80 2.7E-24 T 12-10-2018 IPR002634 BolA protein MIM_c09460 baa4582ad0df3ad875016b5df144f44b 275 Gene3D G3DSA:3.30.950.10 132 272 1.3E-37 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 MIM_c09460 baa4582ad0df3ad875016b5df144f44b 275 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 17 225 2.1E-41 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 MIM_c09460 baa4582ad0df3ad875016b5df144f44b 275 Gene3D G3DSA:3.40.1010.10 14 131 7.7E-36 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 MIM_c09460 baa4582ad0df3ad875016b5df144f44b 275 SUPERFAMILY SSF53790 11 253 1.96E-69 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 MIM_c09460 baa4582ad0df3ad875016b5df144f44b 275 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 16 249 1.8E-81 T 12-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MIM_c09460 baa4582ad0df3ad875016b5df144f44b 275 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 21 35 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MIM_c25570 0c7254c8aaaf2d968d6a4662485d0515 385 ProSitePatterns PS00336 Beta-lactamase class-C active site. 85 92 - T 12-10-2018 IPR001586 Beta-lactamase, class-C active site GO:0008800|GO:0017001|GO:0030288 KEGG: 00311+3.5.2.6 MIM_c25570 0c7254c8aaaf2d968d6a4662485d0515 385 Pfam PF00144 Beta-lactamase 37 381 1.9E-65 T 12-10-2018 IPR001466 Beta-lactamase-related MIM_c25570 0c7254c8aaaf2d968d6a4662485d0515 385 SUPERFAMILY SSF56601 31 383 2.13E-84 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MIM_c25570 0c7254c8aaaf2d968d6a4662485d0515 385 Gene3D G3DSA:3.40.710.10 23 385 2.0E-119 T 12-10-2018 MIM_c12990 6c8f43cab968365e31be4be9fe52f924 453 Gene3D G3DSA:3.90.1150.10 28 439 2.0E-143 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c12990 6c8f43cab968365e31be4be9fe52f924 453 Gene3D G3DSA:3.40.640.10 80 354 2.0E-143 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c12990 6c8f43cab968365e31be4be9fe52f924 453 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 265 302 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MIM_c12990 6c8f43cab968365e31be4be9fe52f924 453 Pfam PF00202 Aminotransferase class-III 44 448 5.3E-108 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MIM_c12990 6c8f43cab968365e31be4be9fe52f924 453 PIRSF PIRSF000521 2 451 2.3E-31 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MIM_c12990 6c8f43cab968365e31be4be9fe52f924 453 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 32 448 3.2E-161 T 12-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 MIM_c12990 6c8f43cab968365e31be4be9fe52f924 453 SUPERFAMILY SSF53383 28 449 1.86E-114 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c26750 d688df2afdef0d1a7a2d4e104fddc989 492 Gene3D G3DSA:3.30.565.10 341 488 1.0E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c26750 d688df2afdef0d1a7a2d4e104fddc989 492 SUPERFAMILY SSF47384 263 333 3.92E-9 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MIM_c26750 d688df2afdef0d1a7a2d4e104fddc989 492 Gene3D G3DSA:1.10.287.130 226 332 2.1E-17 T 12-10-2018 MIM_c26750 d688df2afdef0d1a7a2d4e104fddc989 492 SUPERFAMILY SSF158472 227 275 2.62E-5 T 12-10-2018 MIM_c26750 d688df2afdef0d1a7a2d4e104fddc989 492 SMART SM00387 379 488 1.5E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c26750 d688df2afdef0d1a7a2d4e104fddc989 492 Pfam PF00672 HAMP domain 227 274 2.1E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MIM_c26750 d688df2afdef0d1a7a2d4e104fddc989 492 SMART SM00388 279 337 6.4E-5 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MIM_c26750 d688df2afdef0d1a7a2d4e104fddc989 492 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 381 486 2.8E-15 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c26750 d688df2afdef0d1a7a2d4e104fddc989 492 SMART SM00304 227 278 1.1E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MIM_c26750 d688df2afdef0d1a7a2d4e104fddc989 492 SUPERFAMILY SSF55874 340 488 3.93E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c26750 d688df2afdef0d1a7a2d4e104fddc989 492 PRINTS PR00344 Bacterial sensor protein C-terminal signature 472 485 1.4E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c26750 d688df2afdef0d1a7a2d4e104fddc989 492 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 428 1.4E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c26750 d688df2afdef0d1a7a2d4e104fddc989 492 PRINTS PR00344 Bacterial sensor protein C-terminal signature 448 466 1.4E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c23350 39eed7097bed24900af1fc7d544f33d4 156 Pfam PF02590 Predicted SPOUT methyltransferase 1 154 9.1E-50 T 12-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 MIM_c23350 39eed7097bed24900af1fc7d544f33d4 156 Gene3D G3DSA:3.40.1280.10 1 155 6.1E-50 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MIM_c23350 39eed7097bed24900af1fc7d544f33d4 156 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 155 27.946 T 12-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 MIM_c23350 39eed7097bed24900af1fc7d544f33d4 156 PIRSF PIRSF004505 1 155 1.5E-46 T 12-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 MIM_c23350 39eed7097bed24900af1fc7d544f33d4 156 SUPERFAMILY SSF75217 1 154 8.9E-50 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases MIM_c38320 e5dbe822dae3320c08ac33718ec76098 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 248 1.2E-57 T 12-10-2018 MIM_c38320 e5dbe822dae3320c08ac33718ec76098 252 Gene3D G3DSA:3.40.50.720 1 252 4.8E-67 T 12-10-2018 MIM_c38320 e5dbe822dae3320c08ac33718ec76098 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 3.9E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38320 e5dbe822dae3320c08ac33718ec76098 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 3.9E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38320 e5dbe822dae3320c08ac33718ec76098 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 3.9E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38320 e5dbe822dae3320c08ac33718ec76098 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 7.2E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38320 e5dbe822dae3320c08ac33718ec76098 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 7.2E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38320 e5dbe822dae3320c08ac33718ec76098 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 7.2E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38320 e5dbe822dae3320c08ac33718ec76098 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 7.2E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38320 e5dbe822dae3320c08ac33718ec76098 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 7.2E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38320 e5dbe822dae3320c08ac33718ec76098 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 7.2E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38320 e5dbe822dae3320c08ac33718ec76098 252 SUPERFAMILY SSF51735 1 249 2.46E-70 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c25300 043f35549bfc64779ff3264bf5982584 210 SUPERFAMILY SSF46626 82 184 6.62E-26 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c25300 043f35549bfc64779ff3264bf5982584 210 Gene3D G3DSA:1.10.760.10 68 193 4.4E-44 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c25300 043f35549bfc64779ff3264bf5982584 210 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 82 164 6.7E-13 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c30180 2dc6a810fcaed77d3a34d7bcb1ad291e 392 Pfam PF07690 Major Facilitator Superfamily 9 235 2.2E-29 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c30180 2dc6a810fcaed77d3a34d7bcb1ad291e 392 PRINTS PR01035 Tetracycline resistance protein signature 71 95 3.4E-6 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MIM_c30180 2dc6a810fcaed77d3a34d7bcb1ad291e 392 PRINTS PR01035 Tetracycline resistance protein signature 158 178 3.4E-6 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MIM_c30180 2dc6a810fcaed77d3a34d7bcb1ad291e 392 PRINTS PR01035 Tetracycline resistance protein signature 40 59 3.4E-6 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MIM_c30180 2dc6a810fcaed77d3a34d7bcb1ad291e 392 PRINTS PR01035 Tetracycline resistance protein signature 265 286 3.4E-6 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MIM_c30180 2dc6a810fcaed77d3a34d7bcb1ad291e 392 PRINTS PR01035 Tetracycline resistance protein signature 10 26 3.4E-6 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MIM_c30180 2dc6a810fcaed77d3a34d7bcb1ad291e 392 SUPERFAMILY SSF103473 3 382 3.66E-56 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c30180 2dc6a810fcaed77d3a34d7bcb1ad291e 392 Gene3D G3DSA:1.20.1250.20 3 198 1.3E-25 T 12-10-2018 MIM_c30180 2dc6a810fcaed77d3a34d7bcb1ad291e 392 Gene3D G3DSA:1.20.1250.20 199 384 1.3E-17 T 12-10-2018 MIM_c07910 8f54ce421da3d6e008d850f3512f0992 267 Gene3D G3DSA:3.30.1450.10 55 136 5.3E-12 T 12-10-2018 IPR037873 BamE-like MIM_c07910 8f54ce421da3d6e008d850f3512f0992 267 Pfam PF04355 SmpA / OmlA family 56 127 1.3E-17 T 12-10-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 MIM_c07910 8f54ce421da3d6e008d850f3512f0992 267 Gene3D G3DSA:3.30.1330.60 137 267 2.8E-37 T 12-10-2018 IPR036737 OmpA-like domain superfamily MIM_c07910 8f54ce421da3d6e008d850f3512f0992 267 SUPERFAMILY SSF103088 148 265 2.88E-28 T 12-10-2018 IPR036737 OmpA-like domain superfamily MIM_c07910 8f54ce421da3d6e008d850f3512f0992 267 Pfam PF00691 OmpA family 156 247 1.4E-19 T 12-10-2018 IPR006665 OmpA-like domain MIM_c07910 8f54ce421da3d6e008d850f3512f0992 267 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 205 222 9.7E-6 T 12-10-2018 MIM_c07910 8f54ce421da3d6e008d850f3512f0992 267 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 223 242 9.7E-6 T 12-10-2018 MIM_c07910 8f54ce421da3d6e008d850f3512f0992 267 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 176 202 9.7E-6 T 12-10-2018 MIM_c07910 8f54ce421da3d6e008d850f3512f0992 267 PRINTS PR01021 OMPA domain signature 190 205 4.7E-12 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MIM_c07910 8f54ce421da3d6e008d850f3512f0992 267 PRINTS PR01021 OMPA domain signature 205 221 4.7E-12 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MIM_c07910 8f54ce421da3d6e008d850f3512f0992 267 PRINTS PR01021 OMPA domain signature 159 181 4.7E-12 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MIM_c23620 79c5100f042659c01cd5b32503b5b9c0 230 Pfam PF00877 NlpC/P60 family 114 221 1.8E-29 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain MIM_c23620 79c5100f042659c01cd5b32503b5b9c0 230 SUPERFAMILY SSF54001 103 222 4.9E-42 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily MIM_c23620 79c5100f042659c01cd5b32503b5b9c0 230 Gene3D G3DSA:3.90.1720.10 35 216 1.3E-42 T 12-10-2018 MIM_c02290 f219c744edca71ab63440bbf4906c384 154 Gene3D G3DSA:1.10.150.120 76 153 1.2E-26 T 12-10-2018 MIM_c02290 f219c744edca71ab63440bbf4906c384 154 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 62 2.0E-8 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MIM_c02290 f219c744edca71ab63440bbf4906c384 154 Gene3D G3DSA:3.10.20.30 1 75 1.5E-26 T 12-10-2018 IPR012675 Beta-grasp domain superfamily MIM_c02290 f219c744edca71ab63440bbf4906c384 154 Pfam PF01799 [2Fe-2S] binding domain 72 145 4.9E-27 T 12-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 MIM_c02290 f219c744edca71ab63440bbf4906c384 154 SUPERFAMILY SSF47741 83 149 1.07E-29 T 12-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily MIM_c02290 f219c744edca71ab63440bbf4906c384 154 SUPERFAMILY SSF54292 2 77 3.54E-25 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MIM_c05900 7f551a83008c4de2e0187f70f90e1250 516 Gene3D G3DSA:3.40.190.10 187 499 2.3E-162 T 12-10-2018 MIM_c05900 7f551a83008c4de2e0187f70f90e1250 516 Gene3D G3DSA:3.10.105.10 264 489 2.3E-162 T 12-10-2018 MIM_c05900 7f551a83008c4de2e0187f70f90e1250 516 PIRSF PIRSF002741 10 516 4.5E-111 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MIM_c05900 7f551a83008c4de2e0187f70f90e1250 516 Gene3D G3DSA:3.90.76.10 40 186 2.3E-162 T 12-10-2018 MIM_c05900 7f551a83008c4de2e0187f70f90e1250 516 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 71 432 1.3E-97 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain MIM_c05900 7f551a83008c4de2e0187f70f90e1250 516 SUPERFAMILY SSF53850 31 514 2.53E-140 T 12-10-2018 MIM_c28830 1c03af54aa6761400189179433e10c18 268 SUPERFAMILY SSF53474 7 264 3.54E-38 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c28830 1c03af54aa6761400189179433e10c18 268 Pfam PF00561 alpha/beta hydrolase fold 40 143 2.0E-15 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c28830 1c03af54aa6761400189179433e10c18 268 Gene3D G3DSA:3.40.50.1820 2 263 8.0E-37 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c28830 1c03af54aa6761400189179433e10c18 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 114 127 2.0E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c28830 1c03af54aa6761400189179433e10c18 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 128 141 2.0E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c28830 1c03af54aa6761400189179433e10c18 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 66 81 2.0E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c05970 4af2b74d5a293123fbfdcd432c7ba997 448 SUPERFAMILY SSF55424 335 447 2.58E-37 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MIM_c05970 4af2b74d5a293123fbfdcd432c7ba997 448 Gene3D G3DSA:3.50.50.60 6 317 3.1E-119 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c05970 4af2b74d5a293123fbfdcd432c7ba997 448 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 MIM_c05970 4af2b74d5a293123fbfdcd432c7ba997 448 Gene3D G3DSA:3.50.50.60 145 261 3.1E-119 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c05970 4af2b74d5a293123fbfdcd432c7ba997 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 133 151 6.1E-32 T 12-10-2018 MIM_c05970 4af2b74d5a293123fbfdcd432c7ba997 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 170 188 6.1E-32 T 12-10-2018 MIM_c05970 4af2b74d5a293123fbfdcd432c7ba997 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 270 6.1E-32 T 12-10-2018 MIM_c05970 4af2b74d5a293123fbfdcd432c7ba997 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 6.1E-32 T 12-10-2018 MIM_c05970 4af2b74d5a293123fbfdcd432c7ba997 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 283 305 6.1E-32 T 12-10-2018 MIM_c05970 4af2b74d5a293123fbfdcd432c7ba997 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 334 355 2.3E-70 T 12-10-2018 MIM_c05970 4af2b74d5a293123fbfdcd432c7ba997 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 2.3E-70 T 12-10-2018 MIM_c05970 4af2b74d5a293123fbfdcd432c7ba997 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 399 414 2.3E-70 T 12-10-2018 MIM_c05970 4af2b74d5a293123fbfdcd432c7ba997 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 2.3E-70 T 12-10-2018 MIM_c05970 4af2b74d5a293123fbfdcd432c7ba997 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 255 269 2.3E-70 T 12-10-2018 MIM_c05970 4af2b74d5a293123fbfdcd432c7ba997 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 305 2.3E-70 T 12-10-2018 MIM_c05970 4af2b74d5a293123fbfdcd432c7ba997 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 421 441 2.3E-70 T 12-10-2018 MIM_c05970 4af2b74d5a293123fbfdcd432c7ba997 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 136 145 2.3E-70 T 12-10-2018 MIM_c05970 4af2b74d5a293123fbfdcd432c7ba997 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 170 195 2.3E-70 T 12-10-2018 MIM_c05970 4af2b74d5a293123fbfdcd432c7ba997 448 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 318 9.0E-75 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MIM_c05970 4af2b74d5a293123fbfdcd432c7ba997 448 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 338 446 7.5E-36 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MIM_c05970 4af2b74d5a293123fbfdcd432c7ba997 448 PIRSF PIRSF000350 1 443 1.2E-89 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 MIM_c05970 4af2b74d5a293123fbfdcd432c7ba997 448 SUPERFAMILY SSF51905 3 364 6.48E-66 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c05970 4af2b74d5a293123fbfdcd432c7ba997 448 Gene3D G3DSA:3.30.390.30 337 448 2.2E-48 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MIM_c05970 4af2b74d5a293123fbfdcd432c7ba997 448 TIGRFAM TIGR01424 gluta_reduc_2: glutathione-disulfide reductase 4 447 1.0E-185 T 12-10-2018 IPR006324 Glutathione-disulphide reductase GO:0004362|GO:0006749|GO:0050660|GO:0050661|GO:0055114 KEGG: 00480+1.8.1.7|MetaCyc: PWY-4081 MIM_c29560 f21b752c9f45214b04ead7057cb9dd48 174 SUPERFAMILY SSF53271 17 146 5.77E-30 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like MIM_c29560 f21b752c9f45214b04ead7057cb9dd48 174 Pfam PF00156 Phosphoribosyl transferase domain 10 136 2.9E-13 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MIM_c29560 f21b752c9f45214b04ead7057cb9dd48 174 Gene3D G3DSA:3.40.50.2020 5 168 5.5E-34 T 12-10-2018 MIM_c40670 a55968068cc4c044e40481d5ebffdf1e 144 SMART SM00649 9 141 2.2E-84 T 12-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 MIM_c40670 a55968068cc4c044e40481d5ebffdf1e 144 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 31.476 T 12-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 MIM_c40670 a55968068cc4c044e40481d5ebffdf1e 144 SUPERFAMILY SSF54747 3 73 2.35E-30 T 12-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily MIM_c40670 a55968068cc4c044e40481d5ebffdf1e 144 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 5.0E-24 T 12-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 MIM_c40670 a55968068cc4c044e40481d5ebffdf1e 144 Gene3D G3DSA:3.30.1550.10 2 72 6.4E-35 T 12-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily MIM_c40670 a55968068cc4c044e40481d5ebffdf1e 144 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 12-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c40670 a55968068cc4c044e40481d5ebffdf1e 144 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 7.7E-64 T 12-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c40670 a55968068cc4c044e40481d5ebffdf1e 144 Gene3D G3DSA:1.10.10.250 73 141 1.9E-27 T 12-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily MIM_c40670 a55968068cc4c044e40481d5ebffdf1e 144 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 2.0E-16 T 12-10-2018 MIM_c40670 a55968068cc4c044e40481d5ebffdf1e 144 SUPERFAMILY SSF46906 68 141 2.49E-26 T 12-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily MIM_c40670 a55968068cc4c044e40481d5ebffdf1e 144 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 5.8E-29 T 12-10-2018 IPR020784 Ribosomal protein L11, N-terminal MIM_c03810 43b23616cf8eb334b67d74bf50049365 244 Pfam PF00462 Glutaredoxin 173 231 7.9E-17 T 12-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 MIM_c03810 43b23616cf8eb334b67d74bf50049365 244 Pfam PF08534 Redoxin 5 160 7.0E-34 T 12-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 MIM_c03810 43b23616cf8eb334b67d74bf50049365 244 TIGRFAM TIGR02190 GlrX-dom: glutaredoxin-family domain 166 242 1.0E-31 T 12-10-2018 IPR011906 Glutaredoxin domain KEGG: 00480+1.11.1.15 MIM_c03810 43b23616cf8eb334b67d74bf50049365 244 PRINTS PR00160 Glutaredoxin signature 214 227 3.8E-11 T 12-10-2018 IPR014025 Glutaredoxin subgroup MIM_c03810 43b23616cf8eb334b67d74bf50049365 244 PRINTS PR00160 Glutaredoxin signature 173 191 3.8E-11 T 12-10-2018 IPR014025 Glutaredoxin subgroup MIM_c03810 43b23616cf8eb334b67d74bf50049365 244 PRINTS PR00160 Glutaredoxin signature 228 241 3.8E-11 T 12-10-2018 IPR014025 Glutaredoxin subgroup MIM_c03810 43b23616cf8eb334b67d74bf50049365 244 SUPERFAMILY SSF52833 5 239 4.74E-44 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c03810 43b23616cf8eb334b67d74bf50049365 244 Gene3D G3DSA:3.40.30.10 172 242 1.3E-22 T 12-10-2018 MIM_c03810 43b23616cf8eb334b67d74bf50049365 244 Gene3D G3DSA:3.40.30.10 4 166 2.3E-63 T 12-10-2018 MIM_c18450 6af9e01317c3b3d915c2140220609baa 871 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 850 0.0 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MIM_c18450 6af9e01317c3b3d915c2140220609baa 871 PRINTS PR00980 Alanyl-tRNA synthetase signature 74 85 4.2E-32 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MIM_c18450 6af9e01317c3b3d915c2140220609baa 871 PRINTS PR00980 Alanyl-tRNA synthetase signature 302 315 4.2E-32 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MIM_c18450 6af9e01317c3b3d915c2140220609baa 871 PRINTS PR00980 Alanyl-tRNA synthetase signature 205 216 4.2E-32 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MIM_c18450 6af9e01317c3b3d915c2140220609baa 871 PRINTS PR00980 Alanyl-tRNA synthetase signature 232 245 4.2E-32 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MIM_c18450 6af9e01317c3b3d915c2140220609baa 871 PRINTS PR00980 Alanyl-tRNA synthetase signature 278 294 4.2E-32 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MIM_c18450 6af9e01317c3b3d915c2140220609baa 871 SUPERFAMILY SSF50447 451 549 3.18E-19 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MIM_c18450 6af9e01317c3b3d915c2140220609baa 871 Gene3D G3DSA:3.30.54.20 621 673 9.4E-49 T 12-10-2018 MIM_c18450 6af9e01317c3b3d915c2140220609baa 871 Gene3D G3DSA:3.30.930.10 1 248 4.7E-119 T 12-10-2018 MIM_c18450 6af9e01317c3b3d915c2140220609baa 871 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 871 198.847 T 12-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 MIM_c18450 6af9e01317c3b3d915c2140220609baa 871 SUPERFAMILY SSF101353 252 448 1.96E-59 T 12-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 MIM_c18450 6af9e01317c3b3d915c2140220609baa 871 SMART SM00863 650 692 3.7E-19 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 MIM_c18450 6af9e01317c3b3d915c2140220609baa 871 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 650 692 4.4E-16 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 MIM_c18450 6af9e01317c3b3d915c2140220609baa 871 Pfam PF01411 tRNA synthetases class II (A) 5 553 2.3E-223 T 12-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 MIM_c18450 6af9e01317c3b3d915c2140220609baa 871 SUPERFAMILY SSF55186 549 704 1.83E-48 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 MIM_c18450 6af9e01317c3b3d915c2140220609baa 871 Gene3D G3DSA:3.10.310.40 759 869 6.3E-31 T 12-10-2018 MIM_c18450 6af9e01317c3b3d915c2140220609baa 871 Pfam PF02272 DHHA1 domain 732 867 1.3E-27 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 MIM_c18450 6af9e01317c3b3d915c2140220609baa 871 Gene3D G3DSA:2.40.30.130 457 549 7.0E-11 T 12-10-2018 MIM_c18450 6af9e01317c3b3d915c2140220609baa 871 Gene3D G3DSA:3.30.980.10 559 693 9.4E-49 T 12-10-2018 MIM_c18450 6af9e01317c3b3d915c2140220609baa 871 SUPERFAMILY SSF55681 2 251 1.24E-109 T 12-10-2018 MIM_c02370 742dc921e0ba3d657b632bab556e5c4f 155 SUPERFAMILY SSF82784 2 148 6.94E-44 T 12-10-2018 IPR036102 OsmC/Ohr superfamily MIM_c02370 742dc921e0ba3d657b632bab556e5c4f 155 Pfam PF02566 OsmC-like protein 49 147 1.2E-13 T 12-10-2018 IPR003718 OsmC/Ohr family MIM_c02370 742dc921e0ba3d657b632bab556e5c4f 155 Gene3D G3DSA:3.30.300.20 1 147 1.7E-48 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta MIM_c11090 bd7a792647f4888fa311074e1485ff42 577 SUPERFAMILY SSF52016 379 564 4.87E-56 T 12-10-2018 MIM_c11090 bd7a792647f4888fa311074e1485ff42 577 Pfam PF00920 Dehydratase family 42 558 2.6E-177 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MIM_c11090 bd7a792647f4888fa311074e1485ff42 577 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 125 135 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MIM_c11090 bd7a792647f4888fa311074e1485ff42 577 Gene3D G3DSA:3.50.30.80 378 532 1.3E-46 T 12-10-2018 MIM_c11090 bd7a792647f4888fa311074e1485ff42 577 SUPERFAMILY SSF143975 5 377 3.4E-126 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MIM_c17310 cb23c4fa48ba3eadae6ecb6a2c0ab451 192 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 67 115 3.0E-13 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c17310 cb23c4fa48ba3eadae6ecb6a2c0ab451 192 Gene3D G3DSA:1.20.1290.10 69 192 2.2E-41 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c17310 cb23c4fa48ba3eadae6ecb6a2c0ab451 192 SUPERFAMILY SSF69118 8 189 7.09E-58 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c17310 cb23c4fa48ba3eadae6ecb6a2c0ab451 192 Gene3D G3DSA:1.20.5.810 16 67 2.7E-27 T 12-10-2018 MIM_c17310 cb23c4fa48ba3eadae6ecb6a2c0ab451 192 TIGRFAM TIGR01926 peroxid_rel: uncharacterized peroxidase-related enzyme 10 186 3.9E-67 T 12-10-2018 IPR010195 Uncharacterised peroxidase-related MIM_c17310 cb23c4fa48ba3eadae6ecb6a2c0ab451 192 Pfam PF02627 Carboxymuconolactone decarboxylase family 49 129 9.6E-17 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c37320 cf68f4883843a59a46760f9d6d4f4b8c 328 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 19 78 1.1E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c37320 cf68f4883843a59a46760f9d6d4f4b8c 328 Gene3D G3DSA:3.40.190.10 108 297 3.6E-24 T 12-10-2018 MIM_c37320 cf68f4883843a59a46760f9d6d4f4b8c 328 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 55 66 3.1E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c37320 cf68f4883843a59a46760f9d6d4f4b8c 328 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 55 3.1E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c37320 cf68f4883843a59a46760f9d6d4f4b8c 328 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 45 3.1E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c37320 cf68f4883843a59a46760f9d6d4f4b8c 328 SUPERFAMILY SSF46785 16 126 1.53E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c37320 cf68f4883843a59a46760f9d6d4f4b8c 328 Pfam PF03466 LysR substrate binding domain 107 314 6.1E-15 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c37320 cf68f4883843a59a46760f9d6d4f4b8c 328 Gene3D G3DSA:3.40.190.10 182 286 3.6E-24 T 12-10-2018 MIM_c37320 cf68f4883843a59a46760f9d6d4f4b8c 328 Gene3D G3DSA:1.10.10.10 16 104 2.7E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c37320 cf68f4883843a59a46760f9d6d4f4b8c 328 SUPERFAMILY SSF53850 108 318 3.8E-17 T 12-10-2018 MIM_c27150 d5d6da73a4d409ef3c7c60a9de32e647 381 SUPERFAMILY SSF103473 19 369 3.53E-33 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c27150 d5d6da73a4d409ef3c7c60a9de32e647 381 Pfam PF07690 Major Facilitator Superfamily 23 198 5.8E-12 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c27150 d5d6da73a4d409ef3c7c60a9de32e647 381 Pfam PF07690 Major Facilitator Superfamily 218 367 1.7E-12 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c27150 d5d6da73a4d409ef3c7c60a9de32e647 381 Gene3D G3DSA:1.20.1250.20 16 189 9.5E-13 T 12-10-2018 MIM_c27150 d5d6da73a4d409ef3c7c60a9de32e647 381 Gene3D G3DSA:1.20.1250.20 206 377 1.3E-12 T 12-10-2018 MIM_c17970 4731dc8da3c719b5915d44095ad642b1 305 PIRSF PIRSF005651 1 292 1.2E-85 T 12-10-2018 IPR010200 HflC GO:0016021|GO:0052547 MIM_c17970 4731dc8da3c719b5915d44095ad642b1 305 SUPERFAMILY SSF117892 56 191 1.14E-23 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily MIM_c17970 4731dc8da3c719b5915d44095ad642b1 305 Pfam PF01145 SPFH domain / Band 7 family 24 199 1.4E-24 T 12-10-2018 IPR001107 Band 7 domain MIM_c17970 4731dc8da3c719b5915d44095ad642b1 305 SMART SM00244 20 185 5.7E-28 T 12-10-2018 IPR001107 Band 7 domain MIM_c17970 4731dc8da3c719b5915d44095ad642b1 305 Gene3D G3DSA:3.30.479.30 53 187 3.9E-17 T 12-10-2018 MIM_c17970 4731dc8da3c719b5915d44095ad642b1 305 TIGRFAM TIGR01932 hflC: HflC protein 140 284 4.4E-44 T 12-10-2018 IPR010200 HflC GO:0016021|GO:0052547 MIM_c18690 ed912d4598b7454dfa96b2e47560ab28 570 Gene3D G3DSA:3.10.310.30 329 454 9.3E-31 T 12-10-2018 MIM_c18690 ed912d4598b7454dfa96b2e47560ab28 570 Pfam PF02272 DHHA1 domain 324 449 7.5E-21 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 MIM_c18690 ed912d4598b7454dfa96b2e47560ab28 570 Gene3D G3DSA:3.90.1640.30 50 328 5.6E-84 T 12-10-2018 MIM_c18690 ed912d4598b7454dfa96b2e47560ab28 570 Pfam PF01368 DHH family 77 205 3.7E-9 T 12-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 MIM_c18690 ed912d4598b7454dfa96b2e47560ab28 570 Gene3D G3DSA:2.40.50.460 455 569 1.8E-8 T 12-10-2018 MIM_c18690 ed912d4598b7454dfa96b2e47560ab28 570 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 25 563 6.7E-144 T 12-10-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 MIM_c18690 ed912d4598b7454dfa96b2e47560ab28 570 SUPERFAMILY SSF64182 50 464 1.7E-109 T 12-10-2018 IPR038763 DHH phosphoesterase superfamily MIM_c36020 5a407d78bc65efc0bf07cda9b906eb22 407 Gene3D G3DSA:3.90.420.10 25 279 1.1E-81 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 MIM_c36020 5a407d78bc65efc0bf07cda9b906eb22 407 PRINTS PR00407 Eukaryotic molybdopterin domain signature 223 236 1.5E-20 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 MIM_c36020 5a407d78bc65efc0bf07cda9b906eb22 407 PRINTS PR00407 Eukaryotic molybdopterin domain signature 239 252 1.5E-20 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 MIM_c36020 5a407d78bc65efc0bf07cda9b906eb22 407 PRINTS PR00407 Eukaryotic molybdopterin domain signature 160 175 1.5E-20 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 MIM_c36020 5a407d78bc65efc0bf07cda9b906eb22 407 PRINTS PR00407 Eukaryotic molybdopterin domain signature 361 373 1.5E-20 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 MIM_c36020 5a407d78bc65efc0bf07cda9b906eb22 407 PRINTS PR00407 Eukaryotic molybdopterin domain signature 85 101 1.5E-20 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 MIM_c36020 5a407d78bc65efc0bf07cda9b906eb22 407 PRINTS PR00407 Eukaryotic molybdopterin domain signature 304 318 1.5E-20 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 MIM_c36020 5a407d78bc65efc0bf07cda9b906eb22 407 Pfam PF00174 Oxidoreductase molybdopterin binding domain 97 255 5.5E-48 T 12-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 MIM_c36020 5a407d78bc65efc0bf07cda9b906eb22 407 Gene3D G3DSA:2.60.40.650 280 407 3.1E-45 T 12-10-2018 MIM_c36020 5a407d78bc65efc0bf07cda9b906eb22 407 SUPERFAMILY SSF81296 281 396 1.54E-28 T 12-10-2018 IPR014756 Immunoglobulin E-set MIM_c36020 5a407d78bc65efc0bf07cda9b906eb22 407 TIGRFAM TIGR04555 sulfite_DH_soxC: sulfite dehydrogenase 13 404 9.6E-177 T 12-10-2018 IPR030835 Sulfite dehydrogenase SoxC MIM_c36020 5a407d78bc65efc0bf07cda9b906eb22 407 SUPERFAMILY SSF56524 70 312 1.07E-71 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 MIM_c36020 5a407d78bc65efc0bf07cda9b906eb22 407 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 279 392 1.2E-15 T 12-10-2018 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 MIM_c18150 a57232e9b282e30043359d8d49fca462 197 SUPERFAMILY SSF53955 12 176 8.61E-21 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily MIM_c18150 a57232e9b282e30043359d8d49fca462 197 Gene3D G3DSA:1.10.530.10 36 195 3.5E-9 T 12-10-2018 MIM_c22460 2a424d2eb3282213ad8064aa5563b25b 84 SUPERFAMILY SSF69047 5 45 9.02E-6 T 12-10-2018 IPR036629 YjbJ superfamily MIM_c22460 2a424d2eb3282213ad8064aa5563b25b 84 Pfam PF05532 CsbD-like 6 47 9.3E-12 T 12-10-2018 IPR008462 CsbD-like domain MIM_c07250 1ad3744518039d2284ee20e690aa4082 458 Gene3D G3DSA:3.30.70.1450 367 458 2.9E-28 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MIM_c07250 1ad3744518039d2284ee20e690aa4082 458 SUPERFAMILY SSF116726 135 216 2.62E-5 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MIM_c07250 1ad3744518039d2284ee20e690aa4082 458 SUPERFAMILY SSF116726 381 452 3.01E-12 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MIM_c07250 1ad3744518039d2284ee20e690aa4082 458 Gene3D G3DSA:3.40.50.720 232 366 2.6E-34 T 12-10-2018 MIM_c07250 1ad3744518039d2284ee20e690aa4082 458 Pfam PF02080 TrkA-C domain 390 451 8.3E-14 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MIM_c07250 1ad3744518039d2284ee20e690aa4082 458 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 1.7E-23 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MIM_c07250 1ad3744518039d2284ee20e690aa4082 458 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 1.7E-23 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MIM_c07250 1ad3744518039d2284ee20e690aa4082 458 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 1.7E-23 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MIM_c07250 1ad3744518039d2284ee20e690aa4082 458 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 1.7E-23 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MIM_c07250 1ad3744518039d2284ee20e690aa4082 458 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 1.7E-23 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MIM_c07250 1ad3744518039d2284ee20e690aa4082 458 SUPERFAMILY SSF51735 1 150 1.04E-31 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c07250 1ad3744518039d2284ee20e690aa4082 458 SUPERFAMILY SSF51735 232 373 1.15E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c07250 1ad3744518039d2284ee20e690aa4082 458 Gene3D G3DSA:3.30.70.1450 138 229 1.4E-10 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MIM_c07250 1ad3744518039d2284ee20e690aa4082 458 Gene3D G3DSA:3.40.50.720 2 137 7.0E-41 T 12-10-2018 MIM_c07250 1ad3744518039d2284ee20e690aa4082 458 Pfam PF02254 TrkA-N domain 233 350 1.1E-25 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MIM_c07250 1ad3744518039d2284ee20e690aa4082 458 Pfam PF02254 TrkA-N domain 3 123 5.6E-26 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MIM_c11550 0f2c562abd0f40545be4520bce76876a 190 ProSitePatterns PS01071 grpE protein signature. 143 185 - T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MIM_c11550 0f2c562abd0f40545be4520bce76876a 190 PRINTS PR00773 GrpE protein signature 87 102 1.1E-25 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MIM_c11550 0f2c562abd0f40545be4520bce76876a 190 PRINTS PR00773 GrpE protein signature 59 75 1.1E-25 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MIM_c11550 0f2c562abd0f40545be4520bce76876a 190 PRINTS PR00773 GrpE protein signature 140 155 1.1E-25 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MIM_c11550 0f2c562abd0f40545be4520bce76876a 190 PRINTS PR00773 GrpE protein signature 166 185 1.1E-25 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MIM_c11550 0f2c562abd0f40545be4520bce76876a 190 Gene3D G3DSA:2.30.22.10 133 187 8.6E-20 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 MIM_c11550 0f2c562abd0f40545be4520bce76876a 190 Gene3D G3DSA:3.90.20.20 28 129 1.1E-24 T 12-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 MIM_c11550 0f2c562abd0f40545be4520bce76876a 190 SUPERFAMILY SSF58014 37 129 8.5E-25 T 12-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 MIM_c11550 0f2c562abd0f40545be4520bce76876a 190 SUPERFAMILY SSF51064 136 188 3.27E-15 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 MIM_c11550 0f2c562abd0f40545be4520bce76876a 190 Pfam PF01025 GrpE 33 186 1.0E-47 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MIM_c11550 0f2c562abd0f40545be4520bce76876a 190 Hamap MF_01151 Protein GrpE [grpE]. 3 187 19.548 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MIM_c28670 d615c102e522774cbb1dfb5efea1019f 260 PIRSF PIRSF000094 1 259 5.9E-112 T 12-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MIM_c28670 d615c102e522774cbb1dfb5efea1019f 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 253 7.4E-85 T 12-10-2018 MIM_c28670 d615c102e522774cbb1dfb5efea1019f 260 Gene3D G3DSA:3.40.50.720 2 258 1.2E-54 T 12-10-2018 MIM_c28670 d615c102e522774cbb1dfb5efea1019f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.3E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c28670 d615c102e522774cbb1dfb5efea1019f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.3E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c28670 d615c102e522774cbb1dfb5efea1019f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.3E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c28670 d615c102e522774cbb1dfb5efea1019f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.3E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c28670 d615c102e522774cbb1dfb5efea1019f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.3E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c28670 d615c102e522774cbb1dfb5efea1019f 260 SUPERFAMILY SSF51735 6 254 5.53E-62 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c10480 b1d14ddefe6b7a32cb5e46aea44b0d64 353 SUPERFAMILY SSF56349 63 343 7.65E-49 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MIM_c10480 b1d14ddefe6b7a32cb5e46aea44b0d64 353 Gene3D G3DSA:1.10.443.10 184 350 7.2E-31 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MIM_c10480 b1d14ddefe6b7a32cb5e46aea44b0d64 353 Pfam PF00589 Phage integrase family 188 343 2.1E-19 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MIM_c10480 b1d14ddefe6b7a32cb5e46aea44b0d64 353 Gene3D G3DSA:1.10.150.130 62 183 1.4E-6 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal MIM_c27910 cb716e8b93de0472a58510134b0df99f 211 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 207 3.7E-85 T 12-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 MIM_c27910 cb716e8b93de0472a58510134b0df99f 211 Gene3D G3DSA:3.40.50.2020 2 208 1.4E-70 T 12-10-2018 MIM_c27910 cb716e8b93de0472a58510134b0df99f 211 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 208 43.607 T 12-10-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 MIM_c27910 cb716e8b93de0472a58510134b0df99f 211 Pfam PF14681 Uracil phosphoribosyltransferase 7 207 8.4E-63 T 12-10-2018 MIM_c27910 cb716e8b93de0472a58510134b0df99f 211 SUPERFAMILY SSF53271 3 206 2.1E-65 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like MIM_c16560 c4e58b7e153895281cf466c7a66a439b 594 PRINTS PR00762 Chloride channel signature 370 386 1.1E-21 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MIM_c16560 c4e58b7e153895281cf466c7a66a439b 594 PRINTS PR00762 Chloride channel signature 172 191 1.1E-21 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MIM_c16560 c4e58b7e153895281cf466c7a66a439b 594 PRINTS PR00762 Chloride channel signature 121 140 1.1E-21 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MIM_c16560 c4e58b7e153895281cf466c7a66a439b 594 PRINTS PR00762 Chloride channel signature 388 407 1.1E-21 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MIM_c16560 c4e58b7e153895281cf466c7a66a439b 594 PRINTS PR00762 Chloride channel signature 335 355 1.1E-21 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MIM_c16560 c4e58b7e153895281cf466c7a66a439b 594 Pfam PF00571 CBS domain 459 503 0.0066 T 12-10-2018 IPR000644 CBS domain MIM_c16560 c4e58b7e153895281cf466c7a66a439b 594 SUPERFAMILY SSF54631 447 573 4.27E-15 T 12-10-2018 MIM_c16560 c4e58b7e153895281cf466c7a66a439b 594 Gene3D G3DSA:3.10.580.10 447 583 6.5E-15 T 12-10-2018 MIM_c16560 c4e58b7e153895281cf466c7a66a439b 594 Gene3D G3DSA:1.10.3080.10 21 439 7.1E-87 T 12-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 MIM_c16560 c4e58b7e153895281cf466c7a66a439b 594 Pfam PF00654 Voltage gated chloride channel 80 420 4.6E-79 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MIM_c16560 c4e58b7e153895281cf466c7a66a439b 594 SUPERFAMILY SSF81340 14 434 8.89E-92 T 12-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 MIM_c07080 446861f7b01fc183ad283bad75626178 245 SUPERFAMILY SSF55681 24 242 5.05E-35 T 12-10-2018 MIM_c07080 446861f7b01fc183ad283bad75626178 245 Gene3D G3DSA:3.30.930.10 21 244 2.6E-43 T 12-10-2018 MIM_c31100 5c481cb020d038c7806d80415666d544 750 Gene3D G3DSA:3.30.365.10 595 749 1.2E-35 T 12-10-2018 MIM_c31100 5c481cb020d038c7806d80415666d544 750 PIRSF PIRSF036389 4 744 6.0E-173 T 12-10-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related MIM_c31100 5c481cb020d038c7806d80415666d544 750 Gene3D G3DSA:3.30.365.10 240 571 3.2E-36 T 12-10-2018 MIM_c31100 5c481cb020d038c7806d80415666d544 750 SUPERFAMILY SSF54665 207 291 9.94E-6 T 12-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily MIM_c31100 5c481cb020d038c7806d80415666d544 750 Gene3D G3DSA:3.90.1170.50 177 232 4.5E-7 T 12-10-2018 MIM_c31100 5c481cb020d038c7806d80415666d544 750 SUPERFAMILY SSF56003 324 746 2.21E-100 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 MIM_c31100 5c481cb020d038c7806d80415666d544 750 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 331 556 4.9E-20 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MIM_c31100 5c481cb020d038c7806d80415666d544 750 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 45 186 1.6E-21 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MIM_c31100 5c481cb020d038c7806d80415666d544 750 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 608 690 6.7E-13 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MIM_c31100 5c481cb020d038c7806d80415666d544 750 SMART SM01008 206 292 1.7E-7 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MIM_c31100 5c481cb020d038c7806d80415666d544 750 SUPERFAMILY SSF56003 43 233 1.7E-32 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 MIM_c31100 5c481cb020d038c7806d80415666d544 750 Gene3D G3DSA:3.30.365.10 42 176 6.3E-30 T 12-10-2018 MIM_c22190 01366e0c16da18c31171a02134642694 457 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 4 454 6.4E-211 T 12-10-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 MIM_c22190 01366e0c16da18c31171a02134642694 457 Gene3D G3DSA:3.30.1330.90 11 160 3.4E-53 T 12-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 MIM_c22190 01366e0c16da18c31171a02134642694 457 Pfam PF03313 Serine dehydratase alpha chain 186 451 5.4E-102 T 12-10-2018 IPR005130 Serine dehydratase-like, alpha subunit MIM_c22190 01366e0c16da18c31171a02134642694 457 SUPERFAMILY SSF143548 17 157 5.23E-44 T 12-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 MIM_c22190 01366e0c16da18c31171a02134642694 457 Pfam PF03315 Serine dehydratase beta chain 4 155 2.4E-56 T 12-10-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 MIM_c14780 e0d11c0782a5416315c5dbf5d262f5a4 379 Gene3D G3DSA:2.102.10.10 37 165 2.3E-30 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MIM_c14780 e0d11c0782a5416315c5dbf5d262f5a4 379 Gene3D G3DSA:3.90.380.10 246 379 2.8E-9 T 12-10-2018 MIM_c14780 e0d11c0782a5416315c5dbf5d262f5a4 379 SUPERFAMILY SSF55961 163 376 1.96E-41 T 12-10-2018 MIM_c14780 e0d11c0782a5416315c5dbf5d262f5a4 379 Gene3D G3DSA:3.90.380.10 16 220 2.3E-30 T 12-10-2018 MIM_c14780 e0d11c0782a5416315c5dbf5d262f5a4 379 Pfam PF00355 Rieske [2Fe-2S] domain 41 136 1.9E-11 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MIM_c14780 e0d11c0782a5416315c5dbf5d262f5a4 379 SUPERFAMILY SSF50022 5 155 1.05E-27 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MIM_c14780 e0d11c0782a5416315c5dbf5d262f5a4 379 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 177 378 2.1E-33 T 12-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 MIM_c25020 c6601767cda5166730b7018385ed7a74 270 Gene3D G3DSA:3.30.450.40 105 268 4.5E-16 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c25020 c6601767cda5166730b7018385ed7a74 270 SMART SM00346 27 117 1.5E-18 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c25020 c6601767cda5166730b7018385ed7a74 270 Gene3D G3DSA:1.10.10.10 21 97 6.7E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c25020 c6601767cda5166730b7018385ed7a74 270 SUPERFAMILY SSF55781 85 267 1.96E-21 T 12-10-2018 MIM_c25020 c6601767cda5166730b7018385ed7a74 270 SUPERFAMILY SSF46785 28 99 1.78E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c25020 c6601767cda5166730b7018385ed7a74 270 Pfam PF09339 IclR helix-turn-helix domain 29 78 3.7E-14 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c16040 94d925c328721b46a05ece35b0f8d276 754 Gene3D G3DSA:3.40.50.300 5 266 3.7E-95 T 12-10-2018 MIM_c16040 94d925c328721b46a05ece35b0f8d276 754 Gene3D G3DSA:1.10.10.160 109 181 3.7E-95 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily MIM_c16040 94d925c328721b46a05ece35b0f8d276 754 Gene3D G3DSA:1.10.486.10 376 556 6.2E-114 T 12-10-2018 MIM_c16040 94d925c328721b46a05ece35b0f8d276 754 SUPERFAMILY SSF52540 4 651 9.96E-175 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c16040 94d925c328721b46a05ece35b0f8d276 754 Pfam PF13361 UvrD-like helicase C-terminal domain 271 625 6.6E-70 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MIM_c16040 94d925c328721b46a05ece35b0f8d276 754 Gene3D G3DSA:3.40.50.300 274 643 6.2E-114 T 12-10-2018 MIM_c16040 94d925c328721b46a05ece35b0f8d276 754 Pfam PF00580 UvrD/REP helicase N-terminal domain 5 265 2.2E-75 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 MIM_c40100 8ed1d9bc4a98b924b47fa1ca4284a6d0 370 Gene3D G3DSA:3.10.350.10 33 94 2.7E-5 T 12-10-2018 IPR036779 LysM domain superfamily MIM_c40100 8ed1d9bc4a98b924b47fa1ca4284a6d0 370 Pfam PF04773 FecR protein 124 215 1.0E-11 T 12-10-2018 IPR006860 FecR protein MIM_c40100 8ed1d9bc4a98b924b47fa1ca4284a6d0 370 Pfam PF01476 LysM domain 39 85 9.9E-5 T 12-10-2018 IPR018392 LysM domain MIM_c17410 e5bf256638f1e30b2c8805329a03016a 251 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c17410 e5bf256638f1e30b2c8805329a03016a 251 SUPERFAMILY SSF52540 7 241 6.63E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c17410 e5bf256638f1e30b2c8805329a03016a 251 Gene3D G3DSA:3.40.50.300 5 251 9.6E-74 T 12-10-2018 MIM_c17410 e5bf256638f1e30b2c8805329a03016a 251 Pfam PF00005 ABC transporter 23 171 1.2E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c17410 e5bf256638f1e30b2c8805329a03016a 251 PIRSF PIRSF039085 4 247 3.8E-102 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MIM_c17410 e5bf256638f1e30b2c8805329a03016a 251 SMART SM00382 32 219 1.6E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c07000 d4f81d6b5dd9b127c187830e63867a63 222 SUPERFAMILY SSF46785 147 221 2.54E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c07000 d4f81d6b5dd9b127c187830e63867a63 222 Pfam PF00027 Cyclic nucleotide-binding domain 31 116 1.0E-11 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain MIM_c07000 d4f81d6b5dd9b127c187830e63867a63 222 Gene3D G3DSA:2.60.120.10 5 140 1.9E-15 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c07000 d4f81d6b5dd9b127c187830e63867a63 222 SMART SM00100 11 132 0.001 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain MIM_c07000 d4f81d6b5dd9b127c187830e63867a63 222 Pfam PF13545 Crp-like helix-turn-helix domain 149 220 7.8E-11 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MIM_c07000 d4f81d6b5dd9b127c187830e63867a63 222 SUPERFAMILY SSF51206 10 138 5.63E-22 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like MIM_c07000 d4f81d6b5dd9b127c187830e63867a63 222 Gene3D G3DSA:1.10.10.10 145 220 1.3E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c23430 a65a06de725d4d02c79e36031a4090fb 284 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 21 284 41.406 T 12-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 MIM_c23430 a65a06de725d4d02c79e36031a4090fb 284 SUPERFAMILY SSF140959 27 284 2.22E-103 T 12-10-2018 IPR037217 Tryptophan/Indoleamine 2,3-dioxygenase-like GO:0019441|GO:0020037|GO:0046872 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 MIM_c23430 a65a06de725d4d02c79e36031a4090fb 284 TIGRFAM TIGR03036 trp_2_3_diox: tryptophan 2,3-dioxygenase 21 284 4.5E-132 T 12-10-2018 IPR017485 Tryptophan 2,3-dioxygenase, bacterial GO:0004833|GO:0019441 KEGG: 00380+1.13.11.11 MIM_c23430 a65a06de725d4d02c79e36031a4090fb 284 Pfam PF03301 Tryptophan 2,3-dioxygenase 167 284 2.1E-28 T 12-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 MIM_c23430 a65a06de725d4d02c79e36031a4090fb 284 Pfam PF03301 Tryptophan 2,3-dioxygenase 15 149 9.9E-40 T 12-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 MIM_c23430 a65a06de725d4d02c79e36031a4090fb 284 Gene3D G3DSA:1.20.58.480 25 284 9.9E-99 T 12-10-2018 MIM_c23790 cb6ebf8e54db56d0ea35d4375ec230e0 195 SUPERFAMILY SSF50249 10 82 1.08E-8 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c23790 cb6ebf8e54db56d0ea35d4375ec230e0 195 SUPERFAMILY SSF57863 92 148 3.14E-7 T 12-10-2018 IPR037278 ARFGAP/RecO-like zinc finger MIM_c23790 cb6ebf8e54db56d0ea35d4375ec230e0 195 Pfam PF02565 Recombination protein O C terminal 89 150 1.4E-14 T 12-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 MIM_c23790 cb6ebf8e54db56d0ea35d4375ec230e0 195 Hamap MF_00201 DNA repair protein RecO [recO]. 7 192 13.672 T 12-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 MIM_c23790 cb6ebf8e54db56d0ea35d4375ec230e0 195 Pfam PF11967 Recombination protein O N terminal 11 80 6.5E-16 T 12-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal MIM_c23790 cb6ebf8e54db56d0ea35d4375ec230e0 195 Gene3D G3DSA:1.20.1440.120 85 165 3.0E-23 T 12-10-2018 MIM_c23790 cb6ebf8e54db56d0ea35d4375ec230e0 195 TIGRFAM TIGR00613 reco: DNA repair protein RecO 16 149 2.6E-18 T 12-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 MIM_c23790 cb6ebf8e54db56d0ea35d4375ec230e0 195 Gene3D G3DSA:2.40.50.140 9 84 5.8E-24 T 12-10-2018 MIM_c13710 ba2c15f93c1eefb369b45c584a9f549a 365 Gene3D G3DSA:3.40.50.1820 37 364 8.6E-98 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c13710 ba2c15f93c1eefb369b45c584a9f549a 365 SUPERFAMILY SSF53474 82 361 4.18E-21 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c37730 003192b0d5555d1ab0dda46c7a30fa10 385 SUPERFAMILY SSF53474 133 307 4.3E-7 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c03470 34b207015db23b6b91fd41c5a815fe07 209 PIRSF PIRSF006324 1 209 1.8E-51 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MIM_c03470 34b207015db23b6b91fd41c5a815fe07 209 Pfam PF01810 LysE type translocator 17 207 1.7E-34 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MIM_c12500 7d182f5ed048c27813895f2b9eb59f80 232 SMART SM00882 10 207 1.8E-48 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MIM_c12500 7d182f5ed048c27813895f2b9eb59f80 232 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 48 56 - T 12-10-2018 IPR004164 Coenzyme A transferase active site GO:0008410 Reactome: R-HSA-77108 MIM_c12500 7d182f5ed048c27813895f2b9eb59f80 232 SUPERFAMILY SSF100950 9 221 2.56E-55 T 12-10-2018 IPR037171 NagB/RpiA transferase-like MIM_c12500 7d182f5ed048c27813895f2b9eb59f80 232 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 8 213 1.6E-82 T 12-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 MIM_c12500 7d182f5ed048c27813895f2b9eb59f80 232 Gene3D G3DSA:3.40.1080.10 5 216 9.0E-74 T 12-10-2018 MIM_c12500 7d182f5ed048c27813895f2b9eb59f80 232 Pfam PF01144 Coenzyme A transferase 10 203 1.3E-30 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MIM_c15120 5006a2468ad6c9875c9e06663cdfc4d2 118 SUPERFAMILY SSF52833 7 117 3.16E-24 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c15120 5006a2468ad6c9875c9e06663cdfc4d2 118 Pfam PF03960 ArsC family 57 113 4.5E-8 T 12-10-2018 IPR006660 Arsenate reductase-like MIM_c15120 5006a2468ad6c9875c9e06663cdfc4d2 118 Gene3D G3DSA:3.40.30.10 4 118 1.3E-30 T 12-10-2018 MIM_c34180 0c8df00c751a0065ae4b6ba4a57d0b6e 213 SUPERFAMILY SSF48498 85 198 2.46E-21 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MIM_c34180 0c8df00c751a0065ae4b6ba4a57d0b6e 213 Gene3D G3DSA:1.10.357.10 71 203 2.8E-25 T 12-10-2018 MIM_c34180 0c8df00c751a0065ae4b6ba4a57d0b6e 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 63 5.5E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c34180 0c8df00c751a0065ae4b6ba4a57d0b6e 213 Gene3D G3DSA:1.10.10.60 1 70 2.3E-26 T 12-10-2018 MIM_c34180 0c8df00c751a0065ae4b6ba4a57d0b6e 213 SUPERFAMILY SSF46689 3 88 1.03E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c33820 27cded2567d62550a757d1ff06f31d7c 268 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 255 6.3E-51 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c33820 27cded2567d62550a757d1ff06f31d7c 268 SMART SM00062 38 258 2.0E-42 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c33820 27cded2567d62550a757d1ff06f31d7c 268 SUPERFAMILY SSF53850 11 258 6.48E-57 T 12-10-2018 MIM_c33820 27cded2567d62550a757d1ff06f31d7c 268 Gene3D G3DSA:3.40.190.10 125 216 5.1E-54 T 12-10-2018 MIM_c33820 27cded2567d62550a757d1ff06f31d7c 268 Gene3D G3DSA:3.40.190.10 30 251 5.1E-54 T 12-10-2018 MIM_c26970 3a78c4cdff61f786b3763369560e9d94 371 SUPERFAMILY SSF49401 217 371 1.09E-12 T 12-10-2018 IPR008966 Adhesion domain superfamily MIM_c26970 3a78c4cdff61f786b3763369560e9d94 371 Gene3D G3DSA:2.60.40.1090 215 370 1.8E-19 T 12-10-2018 IPR036937 Fimbrial-type adhesion domain superfamily GO:0007155|GO:0009289 MIM_c26970 3a78c4cdff61f786b3763369560e9d94 371 Pfam PF00419 Fimbrial protein 212 371 9.3E-12 T 12-10-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MIM_c03710 d01a7c33e1f76d7836544ae2bf3fa125 463 SUPERFAMILY SSF52540 6 173 1.44E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c03710 d01a7c33e1f76d7836544ae2bf3fa125 463 Gene3D G3DSA:3.40.50.300 5 187 1.6E-26 T 12-10-2018 MIM_c03710 d01a7c33e1f76d7836544ae2bf3fa125 463 Pfam PF11981 Domain of unknown function (DUF3482) 169 440 1.9E-88 T 12-10-2018 IPR021871 Protein of unknown function DUF3482 MIM_c03710 d01a7c33e1f76d7836544ae2bf3fa125 463 Pfam PF01926 50S ribosome-binding GTPase 9 155 3.5E-17 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 MIM_c38990 7ecf6c573ed12b5ba56fcdf8f0b02821 444 Pfam PF00344 SecY translocase 76 415 1.3E-118 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MIM_c38990 7ecf6c573ed12b5ba56fcdf8f0b02821 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 312 334 2.0E-95 T 12-10-2018 MIM_c38990 7ecf6c573ed12b5ba56fcdf8f0b02821 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 177 200 2.0E-95 T 12-10-2018 MIM_c38990 7ecf6c573ed12b5ba56fcdf8f0b02821 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 367 385 2.0E-95 T 12-10-2018 MIM_c38990 7ecf6c573ed12b5ba56fcdf8f0b02821 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 116 139 2.0E-95 T 12-10-2018 MIM_c38990 7ecf6c573ed12b5ba56fcdf8f0b02821 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 269 288 2.0E-95 T 12-10-2018 MIM_c38990 7ecf6c573ed12b5ba56fcdf8f0b02821 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 23 41 2.0E-95 T 12-10-2018 MIM_c38990 7ecf6c573ed12b5ba56fcdf8f0b02821 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 400 418 2.0E-95 T 12-10-2018 MIM_c38990 7ecf6c573ed12b5ba56fcdf8f0b02821 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 151 176 2.0E-95 T 12-10-2018 MIM_c38990 7ecf6c573ed12b5ba56fcdf8f0b02821 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 75 95 2.0E-95 T 12-10-2018 MIM_c38990 7ecf6c573ed12b5ba56fcdf8f0b02821 444 PIRSF PIRSF004557 2 439 1.7E-126 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MIM_c38990 7ecf6c573ed12b5ba56fcdf8f0b02821 444 ProSitePatterns PS00755 Protein secY signature 1. 76 95 - T 12-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MIM_c38990 7ecf6c573ed12b5ba56fcdf8f0b02821 444 Gene3D G3DSA:1.10.3370.10 12 427 4.3E-165 T 12-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MIM_c38990 7ecf6c573ed12b5ba56fcdf8f0b02821 444 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 20 427 2.5E-134 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MIM_c38990 7ecf6c573ed12b5ba56fcdf8f0b02821 444 SUPERFAMILY SSF103491 14 422 8.11E-133 T 12-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MIM_c38990 7ecf6c573ed12b5ba56fcdf8f0b02821 444 Hamap MF_01465 Protein translocase subunit SecY [secY]. 10 431 29.636 T 12-10-2018 IPR026593 Protein translocase subunit SecY MIM_c38990 7ecf6c573ed12b5ba56fcdf8f0b02821 444 ProSitePatterns PS00756 Protein secY signature 2. 170 187 - T 12-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MIM_c39610 803b4d83f0614430911e69e0f53568fd 746 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 86 746 4.5E-89 T 12-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 MIM_c39610 803b4d83f0614430911e69e0f53568fd 746 Pfam PF00593 TonB dependent receptor 259 745 1.6E-53 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MIM_c39610 803b4d83f0614430911e69e0f53568fd 746 Pfam PF07715 TonB-dependent Receptor Plug Domain 84 182 2.9E-17 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain MIM_c39610 803b4d83f0614430911e69e0f53568fd 746 SUPERFAMILY SSF56935 75 746 1.15E-122 T 12-10-2018 MIM_c39610 803b4d83f0614430911e69e0f53568fd 746 Gene3D G3DSA:2.40.170.20 198 746 2.5E-127 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MIM_c39610 803b4d83f0614430911e69e0f53568fd 746 Gene3D G3DSA:2.170.130.10 66 195 5.6E-41 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MIM_c17490 28f000c616335639362323256e28e8ff 272 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 18 251 4.5E-59 T 12-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 MIM_c17490 28f000c616335639362323256e28e8ff 272 Gene3D G3DSA:3.20.20.60 1 272 1.1E-85 T 12-10-2018 MIM_c17490 28f000c616335639362323256e28e8ff 272 SUPERFAMILY SSF51621 2 262 7.42E-77 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MIM_c09870 c1434c4a169dba989eda67e4be787bc1 283 SUPERFAMILY SSF56655 15 280 7.98E-68 T 12-10-2018 MIM_c09870 c1434c4a169dba989eda67e4be787bc1 283 PRINTS PR00377 Inositol monophosphatase superfamily signature 45 65 1.2E-47 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MIM_c09870 c1434c4a169dba989eda67e4be787bc1 283 PRINTS PR00377 Inositol monophosphatase superfamily signature 67 83 1.2E-47 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MIM_c09870 c1434c4a169dba989eda67e4be787bc1 283 PRINTS PR00377 Inositol monophosphatase superfamily signature 86 102 1.2E-47 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MIM_c09870 c1434c4a169dba989eda67e4be787bc1 283 PRINTS PR00377 Inositol monophosphatase superfamily signature 196 217 1.2E-47 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MIM_c09870 c1434c4a169dba989eda67e4be787bc1 283 PRINTS PR00377 Inositol monophosphatase superfamily signature 227 251 1.2E-47 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MIM_c09870 c1434c4a169dba989eda67e4be787bc1 283 PRINTS PR00377 Inositol monophosphatase superfamily signature 149 172 1.2E-47 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MIM_c09870 c1434c4a169dba989eda67e4be787bc1 283 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 86 99 - T 12-10-2018 IPR020583 Inositol monophosphatase, metal-binding site MIM_c09870 c1434c4a169dba989eda67e4be787bc1 283 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 230 244 - T 12-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 MIM_c09870 c1434c4a169dba989eda67e4be787bc1 283 PRINTS PR01959 SuhB family inositol monophosphatase signature 123 142 3.1E-12 T 12-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 MIM_c09870 c1434c4a169dba989eda67e4be787bc1 283 PRINTS PR01959 SuhB family inositol monophosphatase signature 217 229 3.1E-12 T 12-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 MIM_c09870 c1434c4a169dba989eda67e4be787bc1 283 PRINTS PR01959 SuhB family inositol monophosphatase signature 175 201 3.1E-12 T 12-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 MIM_c09870 c1434c4a169dba989eda67e4be787bc1 283 Pfam PF00459 Inositol monophosphatase family 17 265 8.7E-53 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MIM_c09870 c1434c4a169dba989eda67e4be787bc1 283 Gene3D G3DSA:3.40.190.80 160 281 1.5E-31 T 12-10-2018 MIM_c09870 c1434c4a169dba989eda67e4be787bc1 283 Gene3D G3DSA:3.30.540.10 8 159 2.5E-39 T 12-10-2018 MIM_c27100 f0f2a3d56e2df307ffc6311c0900ed87 247 SMART SM00382 26 213 7.2E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c27100 f0f2a3d56e2df307ffc6311c0900ed87 247 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c27100 f0f2a3d56e2df307ffc6311c0900ed87 247 Gene3D G3DSA:3.40.50.300 1 241 5.7E-78 T 12-10-2018 MIM_c27100 f0f2a3d56e2df307ffc6311c0900ed87 247 Pfam PF00005 ABC transporter 19 165 1.3E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c27100 f0f2a3d56e2df307ffc6311c0900ed87 247 SUPERFAMILY SSF52540 1 235 4.95E-79 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c27100 f0f2a3d56e2df307ffc6311c0900ed87 247 PIRSF PIRSF039085 1 241 1.2E-103 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MIM_c11800 28e8bb0863ae127930964c189cc81821 800 Pfam PF01580 FtsK/SpoIIIE family 413 623 6.3E-67 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MIM_c11800 28e8bb0863ae127930964c189cc81821 800 Pfam PF09397 Ftsk gamma domain 731 791 1.0E-26 T 12-10-2018 IPR018541 FtsK gamma domain MIM_c11800 28e8bb0863ae127930964c189cc81821 800 SMART SM00843 729 794 3.0E-38 T 12-10-2018 IPR018541 FtsK gamma domain MIM_c11800 28e8bb0863ae127930964c189cc81821 800 SUPERFAMILY SSF52540 403 695 1.2E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c11800 28e8bb0863ae127930964c189cc81821 800 Gene3D G3DSA:3.30.980.40 306 410 3.4E-31 T 12-10-2018 MIM_c11800 28e8bb0863ae127930964c189cc81821 800 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 47 225 1.2E-38 T 12-10-2018 IPR025199 DNA translocase FtsK, 4TM region MIM_c11800 28e8bb0863ae127930964c189cc81821 800 Gene3D G3DSA:3.40.50.300 411 708 1.0E-116 T 12-10-2018 MIM_c11800 28e8bb0863ae127930964c189cc81821 800 Gene3D G3DSA:1.10.10.10 726 790 5.0E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c11800 28e8bb0863ae127930964c189cc81821 800 SUPERFAMILY SSF46785 729 794 3.78E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c27710 8fef59a5a9eed989c8d958f82af0360a 293 ProSitePatterns PS01057 SAICAR synthetase signature 1. 106 120 - T 12-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MIM_c27710 8fef59a5a9eed989c8d958f82af0360a 293 Gene3D G3DSA:3.30.200.20 3 104 5.3E-33 T 12-10-2018 MIM_c27710 8fef59a5a9eed989c8d958f82af0360a 293 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 13 293 25.625 T 12-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MIM_c27710 8fef59a5a9eed989c8d958f82af0360a 293 ProSitePatterns PS01058 SAICAR synthetase signature 2. 205 213 - T 12-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MIM_c27710 8fef59a5a9eed989c8d958f82af0360a 293 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 16 290 2.1E-82 T 12-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 MIM_c27710 8fef59a5a9eed989c8d958f82af0360a 293 Gene3D G3DSA:3.30.470.20 106 249 4.7E-58 T 12-10-2018 MIM_c27710 8fef59a5a9eed989c8d958f82af0360a 293 SUPERFAMILY SSF56104 5 293 3.17E-103 T 12-10-2018 MIM_c27710 8fef59a5a9eed989c8d958f82af0360a 293 Pfam PF01259 SAICAR synthetase 16 269 1.8E-103 T 12-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MIM_c04330 1a60d3ee89994bba2174a2ed763e4a48 206 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 185 2.2E-49 T 12-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 MIM_c04330 1a60d3ee89994bba2174a2ed763e4a48 206 SUPERFAMILY SSF52016 1 191 1.14E-45 T 12-10-2018 MIM_c04330 1a60d3ee89994bba2174a2ed763e4a48 206 Pfam PF00694 Aconitase C-terminal domain 3 123 7.6E-25 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 MIM_c04330 1a60d3ee89994bba2174a2ed763e4a48 206 Gene3D G3DSA:3.20.19.10 1 173 3.4E-60 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 MIM_c17010 720a09e5c534c88035ba95648d1ef48e 481 Gene3D G3DSA:1.20.1720.10 17 226 9.1E-46 T 12-10-2018 MIM_c17010 720a09e5c534c88035ba95648d1ef48e 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 19 43 2.1E-5 T 12-10-2018 MIM_c17010 720a09e5c534c88035ba95648d1ef48e 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 110 130 2.1E-5 T 12-10-2018 MIM_c17010 720a09e5c534c88035ba95648d1ef48e 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 413 432 2.1E-5 T 12-10-2018 MIM_c17010 720a09e5c534c88035ba95648d1ef48e 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 140 164 2.1E-5 T 12-10-2018 MIM_c17010 720a09e5c534c88035ba95648d1ef48e 481 SUPERFAMILY SSF103473 8 469 7.46E-60 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c17010 720a09e5c534c88035ba95648d1ef48e 481 Pfam PF07690 Major Facilitator Superfamily 21 423 1.2E-44 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c17010 720a09e5c534c88035ba95648d1ef48e 481 Gene3D G3DSA:1.20.1250.20 268 475 1.5E-12 T 12-10-2018 MIM_c07060 d35acfa39a41b8c7a1d5343bdff339f8 283 SMART SM00382 46 222 4.5E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c07060 d35acfa39a41b8c7a1d5343bdff339f8 283 SUPERFAMILY SSF52540 20 260 8.91E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c07060 d35acfa39a41b8c7a1d5343bdff339f8 283 Pfam PF00005 ABC transporter 37 188 4.8E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c07060 d35acfa39a41b8c7a1d5343bdff339f8 283 Gene3D G3DSA:3.40.50.300 17 262 1.9E-51 T 12-10-2018 MIM_c02810 356f372408338fa8dc7c79bcb536575d 325 SMART SM00382 27 227 2.8E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c02810 356f372408338fa8dc7c79bcb536575d 325 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 228 313 1.0E-25 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c02810 356f372408338fa8dc7c79bcb536575d 325 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c02810 356f372408338fa8dc7c79bcb536575d 325 Pfam PF00005 ABC transporter 18 177 1.7E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c02810 356f372408338fa8dc7c79bcb536575d 325 SUPERFAMILY SSF52540 27 300 7.34E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c02810 356f372408338fa8dc7c79bcb536575d 325 Gene3D G3DSA:3.40.50.300 1 324 3.5E-104 T 12-10-2018 MIM_c02810 356f372408338fa8dc7c79bcb536575d 325 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 229 293 4.2E-19 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c08940 f0dd2d2e1e89e598bd6b992e425889c5 593 SUPERFAMILY SSF90123 15 319 3.01E-46 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MIM_c08940 f0dd2d2e1e89e598bd6b992e425889c5 593 Gene3D G3DSA:3.40.50.300 328 584 1.7E-75 T 12-10-2018 MIM_c08940 f0dd2d2e1e89e598bd6b992e425889c5 593 Pfam PF00005 ABC transporter 351 500 2.5E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c08940 f0dd2d2e1e89e598bd6b992e425889c5 593 SMART SM00382 360 552 8.4E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c08940 f0dd2d2e1e89e598bd6b992e425889c5 593 Gene3D G3DSA:1.20.1560.10 1 325 9.9E-44 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MIM_c08940 f0dd2d2e1e89e598bd6b992e425889c5 593 SUPERFAMILY SSF52540 331 570 2.57E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c08940 f0dd2d2e1e89e598bd6b992e425889c5 593 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c08940 f0dd2d2e1e89e598bd6b992e425889c5 593 Pfam PF00664 ABC transporter transmembrane region 64 292 3.6E-19 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MIM_c39090 163737a191e82d290ef51da9c0515525 122 SUPERFAMILY SSF50193 1 122 1.96E-49 T 12-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 MIM_c39090 163737a191e82d290ef51da9c0515525 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 12-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39090 163737a191e82d290ef51da9c0515525 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 1.3E-52 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MIM_c39090 163737a191e82d290ef51da9c0515525 122 Gene3D G3DSA:2.40.150.20 1 122 8.7E-52 T 12-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 MIM_c39090 163737a191e82d290ef51da9c0515525 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.272 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MIM_c39090 163737a191e82d290ef51da9c0515525 122 SMART SM01374 1 122 3.9E-81 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MIM_c39090 163737a191e82d290ef51da9c0515525 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 1.5E-56 T 12-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 MIM_24p00090 4811673a4c519ae494bf4a39dc9ac1ea 447 Pfam PF00330 Aconitase family (aconitate hydratase) 9 445 1.0E-147 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_24p00090 4811673a4c519ae494bf4a39dc9ac1ea 447 SUPERFAMILY SSF53732 4 444 3.27E-150 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 MIM_24p00090 4811673a4c519ae494bf4a39dc9ac1ea 447 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 3 447 52.035 T 12-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 MIM_24p00090 4811673a4c519ae494bf4a39dc9ac1ea 447 Gene3D G3DSA:3.30.499.10 332 447 4.9E-38 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 MIM_24p00090 4811673a4c519ae494bf4a39dc9ac1ea 447 ProSitePatterns PS01244 Aconitase family signature 2. 406 419 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MIM_24p00090 4811673a4c519ae494bf4a39dc9ac1ea 447 ProSitePatterns PS00450 Aconitase family signature 1. 345 361 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MIM_24p00090 4811673a4c519ae494bf4a39dc9ac1ea 447 PRINTS PR00415 Aconitase family signature 114 122 2.5E-49 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_24p00090 4811673a4c519ae494bf4a39dc9ac1ea 447 PRINTS PR00415 Aconitase family signature 215 228 2.5E-49 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_24p00090 4811673a4c519ae494bf4a39dc9ac1ea 447 PRINTS PR00415 Aconitase family signature 349 360 2.5E-49 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_24p00090 4811673a4c519ae494bf4a39dc9ac1ea 447 PRINTS PR00415 Aconitase family signature 88 101 2.5E-49 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_24p00090 4811673a4c519ae494bf4a39dc9ac1ea 447 PRINTS PR00415 Aconitase family signature 139 154 2.5E-49 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_24p00090 4811673a4c519ae494bf4a39dc9ac1ea 447 PRINTS PR00415 Aconitase family signature 201 214 2.5E-49 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_24p00090 4811673a4c519ae494bf4a39dc9ac1ea 447 PRINTS PR00415 Aconitase family signature 406 419 2.5E-49 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_24p00090 4811673a4c519ae494bf4a39dc9ac1ea 447 PRINTS PR00415 Aconitase family signature 292 306 2.5E-49 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_24p00090 4811673a4c519ae494bf4a39dc9ac1ea 447 PRINTS PR00415 Aconitase family signature 125 138 2.5E-49 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_24p00090 4811673a4c519ae494bf4a39dc9ac1ea 447 Gene3D G3DSA:3.30.499.20 7 292 2.0E-94 T 12-10-2018 MIM_24p00090 4811673a4c519ae494bf4a39dc9ac1ea 447 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 4 446 1.6E-201 T 12-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 MIM_c36360 597524755699829b9e53d80a4ca64e46 324 PIRSF PIRSF017082 6 322 1.1E-63 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c36360 597524755699829b9e53d80a4ca64e46 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 319 1.5E-55 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c36360 597524755699829b9e53d80a4ca64e46 324 SUPERFAMILY SSF53850 31 278 3.2E-14 T 12-10-2018 MIM_c36360 597524755699829b9e53d80a4ca64e46 324 Gene3D G3DSA:3.40.190.10 126 248 5.2E-84 T 12-10-2018 MIM_c36360 597524755699829b9e53d80a4ca64e46 324 Gene3D G3DSA:3.40.190.150 30 313 5.2E-84 T 12-10-2018 MIM_c38340 89dceb58b89da05c41a39e2bdfa4102c 400 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 227 1.6E-20 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MIM_c38340 89dceb58b89da05c41a39e2bdfa4102c 400 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 240 393 6.5E-23 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MIM_c38340 89dceb58b89da05c41a39e2bdfa4102c 400 Gene3D G3DSA:1.20.140.10 244 399 9.2E-21 T 12-10-2018 MIM_c38340 89dceb58b89da05c41a39e2bdfa4102c 400 SUPERFAMILY SSF56645 18 249 5.89E-62 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c38340 89dceb58b89da05c41a39e2bdfa4102c 400 SUPERFAMILY SSF47203 240 397 1.77E-14 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c38340 89dceb58b89da05c41a39e2bdfa4102c 400 Gene3D G3DSA:1.10.540.10 14 127 8.9E-22 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c38340 89dceb58b89da05c41a39e2bdfa4102c 400 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 18 127 5.7E-16 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c38340 89dceb58b89da05c41a39e2bdfa4102c 400 Gene3D G3DSA:2.40.110.10 133 243 1.2E-34 T 12-10-2018 MIM_c14300 3aa2a19c1f6e7a6e1d1354c53882552e 189 Gene3D G3DSA:3.90.1590.10 1 189 4.5E-88 T 12-10-2018 MIM_c14300 3aa2a19c1f6e7a6e1d1354c53882552e 189 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 48 110 4.5E-10 T 12-10-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 MIM_c14300 3aa2a19c1f6e7a6e1d1354c53882552e 189 TIGRFAM TIGR02820 formald_GSH: S-(hydroxymethyl)glutathione synthase 5 186 3.8E-98 T 12-10-2018 IPR014185 Glutathione-dependent formaldehyde-activating enzyme GO:0008270|GO:0046294|GO:0051907 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 MIM_c14300 3aa2a19c1f6e7a6e1d1354c53882552e 189 PIRSF PIRSF033318 1 189 6.3E-99 T 12-10-2018 IPR014185 Glutathione-dependent formaldehyde-activating enzyme GO:0008270|GO:0046294|GO:0051907 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 MIM_c14300 3aa2a19c1f6e7a6e1d1354c53882552e 189 SUPERFAMILY SSF51316 3 187 5.23E-52 T 12-10-2018 IPR011057 Mss4-like superfamily MIM_c14300 3aa2a19c1f6e7a6e1d1354c53882552e 189 Hamap MF_00723 Glutathione-dependent formaldehyde-activating enzyme [gfa]. 1 189 117.261 T 12-10-2018 IPR014185 Glutathione-dependent formaldehyde-activating enzyme GO:0008270|GO:0046294|GO:0051907 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 MIM_c23060 21d72ec9cdeeb97bc0469fd142fe297f 156 Pfam PF00545 ribonuclease 65 150 7.2E-22 T 12-10-2018 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 MIM_c23060 21d72ec9cdeeb97bc0469fd142fe297f 156 Gene3D G3DSA:3.10.450.30 42 152 3.3E-32 T 12-10-2018 MIM_c23060 21d72ec9cdeeb97bc0469fd142fe297f 156 SUPERFAMILY SSF53933 52 152 1.7E-25 T 12-10-2018 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 MIM_c10850 d45363eb4c545293aded4569e3cdf206 396 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 14 392 6.8E-58 T 12-10-2018 IPR024455 Phage capsid MIM_c10850 d45363eb4c545293aded4569e3cdf206 396 Gene3D G3DSA:3.30.2400.10 152 384 2.0E-93 T 12-10-2018 MIM_c10850 d45363eb4c545293aded4569e3cdf206 396 Pfam PF05065 Phage capsid family 123 393 5.3E-60 T 12-10-2018 IPR024455 Phage capsid MIM_c10850 d45363eb4c545293aded4569e3cdf206 396 Gene3D G3DSA:3.30.2320.10 251 389 2.0E-93 T 12-10-2018 MIM_c10850 d45363eb4c545293aded4569e3cdf206 396 SUPERFAMILY SSF56563 118 394 1.05E-79 T 12-10-2018 MIM_c32960 f221ecfe3a2e3ff495b4ce3d774fde84 754 SUPERFAMILY SSF53383 151 604 2.72E-115 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c32960 f221ecfe3a2e3ff495b4ce3d774fde84 754 Gene3D G3DSA:3.90.1150.10 459 630 3.2E-70 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c32960 f221ecfe3a2e3ff495b4ce3d774fde84 754 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 151 584 3.5E-153 T 12-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 MIM_c32960 f221ecfe3a2e3ff495b4ce3d774fde84 754 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 392 406 - T 12-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 MIM_c32960 f221ecfe3a2e3ff495b4ce3d774fde84 754 PIRSF PIRSF009393 1 751 1.3E-275 T 12-10-2018 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 MIM_c32960 f221ecfe3a2e3ff495b4ce3d774fde84 754 Gene3D G3DSA:3.40.50.2300 5 149 1.1E-20 T 12-10-2018 MIM_c32960 f221ecfe3a2e3ff495b4ce3d774fde84 754 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 611 734 4.6E-44 T 12-10-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 MIM_c32960 f221ecfe3a2e3ff495b4ce3d774fde84 754 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 20 145 6.7E-38 T 12-10-2018 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 MIM_c32960 f221ecfe3a2e3ff495b4ce3d774fde84 754 SUPERFAMILY SSF55904 605 751 4.97E-43 T 12-10-2018 IPR036633 Orn/Lys/Arg decarboxylase, C-terminal domain superfamily GO:0003824 MIM_c32960 f221ecfe3a2e3ff495b4ce3d774fde84 754 Gene3D G3DSA:3.90.100.10 631 752 4.9E-37 T 12-10-2018 MIM_c32960 f221ecfe3a2e3ff495b4ce3d774fde84 754 Gene3D G3DSA:3.40.640.10 151 456 8.3E-95 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c17400 eb70ad5098b2bd399823bee3f3b505fe 284 SMART SM00062 31 252 4.4E-46 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c17400 eb70ad5098b2bd399823bee3f3b505fe 284 SUPERFAMILY SSF53850 29 251 4.54E-54 T 12-10-2018 MIM_c17400 eb70ad5098b2bd399823bee3f3b505fe 284 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 32 250 1.3E-49 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c17400 eb70ad5098b2bd399823bee3f3b505fe 284 Gene3D G3DSA:3.40.190.10 116 211 3.1E-52 T 12-10-2018 MIM_c17400 eb70ad5098b2bd399823bee3f3b505fe 284 Gene3D G3DSA:3.40.190.10 35 248 3.1E-52 T 12-10-2018 MIM_c11490 36232a59aeadf09f3f83201de7f10ffb 144 Gene3D G3DSA:1.10.10.10 3 86 3.3E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c11490 36232a59aeadf09f3f83201de7f10ffb 144 Pfam PF01475 Ferric uptake regulator family 13 132 3.3E-43 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 MIM_c11490 36232a59aeadf09f3f83201de7f10ffb 144 Gene3D G3DSA:3.30.1490.190 88 142 2.6E-24 T 12-10-2018 MIM_c11490 36232a59aeadf09f3f83201de7f10ffb 144 SUPERFAMILY SSF46785 9 137 2.18E-40 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c15620 2d8317e316e592a884a1474ab556b237 90 SUPERFAMILY SSF47729 1 90 8.39E-33 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 MIM_c15620 2d8317e316e592a884a1474ab556b237 90 SMART SM00411 1 90 3.1E-40 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MIM_c15620 2d8317e316e592a884a1474ab556b237 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 3.3E-33 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MIM_c15620 2d8317e316e592a884a1474ab556b237 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 12-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 MIM_c15620 2d8317e316e592a884a1474ab556b237 90 Gene3D G3DSA:4.10.520.10 1 90 3.7E-36 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 MIM_c15620 2d8317e316e592a884a1474ab556b237 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 6.4E-19 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MIM_c15620 2d8317e316e592a884a1474ab556b237 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 6.4E-19 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MIM_c15620 2d8317e316e592a884a1474ab556b237 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 6.4E-19 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MIM_c34360 510d113b383617938e059c4f2bc84d53 350 Gene3D G3DSA:3.40.190.10 135 314 5.3E-37 T 12-10-2018 MIM_c34360 510d113b383617938e059c4f2bc84d53 350 Pfam PF13343 Bacterial extracellular solute-binding protein 85 308 4.5E-37 T 12-10-2018 MIM_c34360 510d113b383617938e059c4f2bc84d53 350 Gene3D G3DSA:3.40.190.10 59 312 5.3E-37 T 12-10-2018 MIM_c34360 510d113b383617938e059c4f2bc84d53 350 SUPERFAMILY SSF53850 34 342 1.7E-48 T 12-10-2018 MIM_c33910 bf25b428035dfa45a1b3db44ef5b4a6b 327 SUPERFAMILY SSF53850 36 274 2.21E-45 T 12-10-2018 MIM_c33910 bf25b428035dfa45a1b3db44ef5b4a6b 327 Gene3D G3DSA:3.40.190.10 38 320 3.0E-69 T 12-10-2018 MIM_c33910 bf25b428035dfa45a1b3db44ef5b4a6b 327 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 38 325 9.0E-54 T 12-10-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 MIM_c33910 bf25b428035dfa45a1b3db44ef5b4a6b 327 Gene3D G3DSA:1.10.8.450 253 287 3.0E-69 T 12-10-2018 MIM_c33910 bf25b428035dfa45a1b3db44ef5b4a6b 327 SMART SM00062 37 258 1.0E-7 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c33910 bf25b428035dfa45a1b3db44ef5b4a6b 327 Gene3D G3DSA:3.40.190.10 119 219 3.0E-69 T 12-10-2018 MIM_c33910 bf25b428035dfa45a1b3db44ef5b4a6b 327 Pfam PF09084 NMT1/THI5 like 49 261 1.9E-25 T 12-10-2018 IPR015168 SsuA/THI5-like MIM_c19070 7c79358d542c30093b6cf1637f122d9e 436 Gene3D G3DSA:3.40.190.10 29 382 2.3E-134 T 12-10-2018 MIM_c19070 7c79358d542c30093b6cf1637f122d9e 436 SUPERFAMILY SSF53850 27 425 2.52E-77 T 12-10-2018 MIM_c19070 7c79358d542c30093b6cf1637f122d9e 436 Gene3D G3DSA:3.40.190.10 145 422 2.3E-134 T 12-10-2018 MIM_c19070 7c79358d542c30093b6cf1637f122d9e 436 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 140 157 - T 12-10-2018 IPR006061 Solute-binding family 1, conserved site GO:0055085 MIM_c19070 7c79358d542c30093b6cf1637f122d9e 436 Pfam PF13416 Bacterial extracellular solute-binding protein 44 366 2.1E-46 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein MIM_c29790 c68f9991d6bfbac7b3b7ebf1d661d03e 335 SUPERFAMILY SSF46689 282 334 8.51E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c29790 c68f9991d6bfbac7b3b7ebf1d661d03e 335 SUPERFAMILY SSF46689 230 279 7.08E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c29790 c68f9991d6bfbac7b3b7ebf1d661d03e 335 SMART SM00342 245 331 6.6E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c29790 c68f9991d6bfbac7b3b7ebf1d661d03e 335 Gene3D G3DSA:1.10.10.60 228 335 4.6E-28 T 12-10-2018 MIM_c29790 c68f9991d6bfbac7b3b7ebf1d661d03e 335 Pfam PF12833 Helix-turn-helix domain 251 333 1.3E-27 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c09760 638b770064a1086bb80cf51841f83c9b 362 Gene3D G3DSA:3.40.50.2000 12 348 8.8E-106 T 12-10-2018 MIM_c09760 638b770064a1086bb80cf51841f83c9b 362 SUPERFAMILY SSF53756 10 357 1.19E-115 T 12-10-2018 MIM_c09760 638b770064a1086bb80cf51841f83c9b 362 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 11 358 33.666 T 12-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c09760 638b770064a1086bb80cf51841f83c9b 362 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 188 349 2.5E-35 T 12-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 MIM_c09760 638b770064a1086bb80cf51841f83c9b 362 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 7 353 1.0E-96 T 12-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c09760 638b770064a1086bb80cf51841f83c9b 362 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 12 144 1.9E-34 T 12-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c09760 638b770064a1086bb80cf51841f83c9b 362 Gene3D G3DSA:3.40.50.2000 165 342 8.8E-106 T 12-10-2018 MIM_c01080 19a2b3c68144fd5af6917cee973eea16 500 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 3 495 2.2E-212 T 12-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 MIM_c01080 19a2b3c68144fd5af6917cee973eea16 500 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 258 451 1.9E-63 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 MIM_c01080 19a2b3c68144fd5af6917cee973eea16 500 Gene3D G3DSA:3.30.420.40 1 250 1.2E-105 T 12-10-2018 MIM_c01080 19a2b3c68144fd5af6917cee973eea16 500 SUPERFAMILY SSF53067 252 495 5.18E-76 T 12-10-2018 MIM_c01080 19a2b3c68144fd5af6917cee973eea16 500 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 359 379 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MIM_c01080 19a2b3c68144fd5af6917cee973eea16 500 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 133 145 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MIM_c01080 19a2b3c68144fd5af6917cee973eea16 500 PIRSF PIRSF000538 1 500 3.7E-175 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MIM_c01080 19a2b3c68144fd5af6917cee973eea16 500 SUPERFAMILY SSF53067 3 252 6.31E-92 T 12-10-2018 MIM_c01080 19a2b3c68144fd5af6917cee973eea16 500 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 249 1.3E-74 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 MIM_c01080 19a2b3c68144fd5af6917cee973eea16 500 Gene3D G3DSA:3.30.420.40 251 499 2.4E-84 T 12-10-2018 MIM_c01080 19a2b3c68144fd5af6917cee973eea16 500 Hamap MF_00186 Glycerol kinase [glpK]. 1 498 55.112 T 12-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 MIM_c05570 a5c2896009b4200b341f1b8197560280 208 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 9 181 4.6E-34 T 12-10-2018 IPR010664 Lipopolysaccharide assembly, LptC-related MIM_c05570 a5c2896009b4200b341f1b8197560280 208 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 8 183 1.1E-34 T 12-10-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 MIM_c02970 a498b8b17dc11c634fdc4bd85645fd07 514 SMART SM01002 146 312 4.0E-85 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MIM_c02970 a498b8b17dc11c634fdc4bd85645fd07 514 SUPERFAMILY SSF52283 1 168 5.19E-55 T 12-10-2018 MIM_c02970 a498b8b17dc11c634fdc4bd85645fd07 514 SUPERFAMILY SSF51735 138 318 1.88E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c02970 a498b8b17dc11c634fdc4bd85645fd07 514 SMART SM01003 4 137 1.0E-72 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MIM_c02970 a498b8b17dc11c634fdc4bd85645fd07 514 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 427 510 1.9E-34 T 12-10-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 MIM_c02970 a498b8b17dc11c634fdc4bd85645fd07 514 PIRSF PIRSF000203 1 510 6.8E-263 T 12-10-2018 IPR026255 NAD(P) transhydrogenase, alpha subunit GO:0008746|GO:0055114|GO:1902600 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 MIM_c02970 a498b8b17dc11c634fdc4bd85645fd07 514 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 3.8E-50 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MIM_c02970 a498b8b17dc11c634fdc4bd85645fd07 514 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 170 195 - T 12-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 MIM_c02970 a498b8b17dc11c634fdc4bd85645fd07 514 Gene3D G3DSA:3.40.50.720 3 365 2.8E-161 T 12-10-2018 MIM_c02970 a498b8b17dc11c634fdc4bd85645fd07 514 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 4 30 - T 12-10-2018 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 Reactome: R-HSA-71403 MIM_c02970 a498b8b17dc11c634fdc4bd85645fd07 514 TIGRFAM TIGR00561 pntA: NAD(P)(+) transhydrogenase (AB-specific), alpha subunit 2 510 1.2E-264 T 12-10-2018 IPR026255 NAD(P) transhydrogenase, alpha subunit GO:0008746|GO:0055114|GO:1902600 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 MIM_c02970 a498b8b17dc11c634fdc4bd85645fd07 514 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 369 6.2E-76 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MIM_c02970 a498b8b17dc11c634fdc4bd85645fd07 514 Gene3D G3DSA:3.40.50.720 137 319 2.8E-161 T 12-10-2018 MIM_c34190 88674e37aca0a1f1c7749d69a806c4c4 407 Gene3D G3DSA:1.20.1250.20 18 392 8.2E-47 T 12-10-2018 MIM_c34190 88674e37aca0a1f1c7749d69a806c4c4 407 Pfam PF07690 Major Facilitator Superfamily 24 349 7.8E-34 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c34190 88674e37aca0a1f1c7749d69a806c4c4 407 SUPERFAMILY SSF103473 17 387 9.16E-54 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c05370 71bb5d837676d4d6508f90bd9fd118e0 507 Gene3D G3DSA:3.60.120.10 1 502 1.6E-167 T 12-10-2018 IPR005801 ADC synthase GO:0009058 MIM_c05370 71bb5d837676d4d6508f90bd9fd118e0 507 Pfam PF04715 Anthranilate synthase component I, N terminal region 27 178 1.2E-25 T 12-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MIM_c05370 71bb5d837676d4d6508f90bd9fd118e0 507 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 27 496 5.8E-160 T 12-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MIM_c05370 71bb5d837676d4d6508f90bd9fd118e0 507 PRINTS PR00095 Anthranilate synthase component I signature 350 363 9.4E-23 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MIM_c05370 71bb5d837676d4d6508f90bd9fd118e0 507 PRINTS PR00095 Anthranilate synthase component I signature 445 459 9.4E-23 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MIM_c05370 71bb5d837676d4d6508f90bd9fd118e0 507 PRINTS PR00095 Anthranilate synthase component I signature 336 349 9.4E-23 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MIM_c05370 71bb5d837676d4d6508f90bd9fd118e0 507 PRINTS PR00095 Anthranilate synthase component I signature 430 444 9.4E-23 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MIM_c05370 71bb5d837676d4d6508f90bd9fd118e0 507 SUPERFAMILY SSF56322 15 496 3.92E-150 T 12-10-2018 IPR005801 ADC synthase GO:0009058 MIM_c05370 71bb5d837676d4d6508f90bd9fd118e0 507 Pfam PF00425 chorismate binding enzyme 227 488 2.3E-94 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal MIM_c39670 8deaacc870f9f8eac9d5fa8b7e86374a 91 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 3.1E-23 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39670 8deaacc870f9f8eac9d5fa8b7e86374a 91 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 3.1E-23 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39670 8deaacc870f9f8eac9d5fa8b7e86374a 91 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 3.1E-23 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39670 8deaacc870f9f8eac9d5fa8b7e86374a 91 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 12-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39670 8deaacc870f9f8eac9d5fa8b7e86374a 91 Gene3D G3DSA:3.30.860.10 1 91 1.7E-41 T 12-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39670 8deaacc870f9f8eac9d5fa8b7e86374a 91 SUPERFAMILY SSF54570 2 84 4.71E-35 T 12-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39670 8deaacc870f9f8eac9d5fa8b7e86374a 91 Pfam PF00203 Ribosomal protein S19 3 83 1.3E-36 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39670 8deaacc870f9f8eac9d5fa8b7e86374a 91 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 91 4.2E-46 T 12-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 MIM_c39670 8deaacc870f9f8eac9d5fa8b7e86374a 91 PIRSF PIRSF002144 1 91 2.1E-32 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39670 8deaacc870f9f8eac9d5fa8b7e86374a 91 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.341 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c05940 9e68f78b7f6fb915096b86ce1d654378 274 SUPERFAMILY SSF63992 1 273 7.45E-93 T 12-10-2018 IPR036177 Peptidase M55, D-aminopeptidase superfamily MIM_c05940 9e68f78b7f6fb915096b86ce1d654378 274 Gene3D G3DSA:3.40.50.10780 1 216 6.6E-84 T 12-10-2018 IPR027476 D-aminopeptidase, N-terminal MIM_c05940 9e68f78b7f6fb915096b86ce1d654378 274 Gene3D G3DSA:3.30.1360.130 118 262 6.6E-84 T 12-10-2018 MIM_c05940 9e68f78b7f6fb915096b86ce1d654378 274 PIRSF PIRSF015853 1 274 1.7E-94 T 12-10-2018 IPR007035 Peptidase M55, D-aminopeptidase MIM_c05940 9e68f78b7f6fb915096b86ce1d654378 274 Pfam PF04951 D-aminopeptidase 1 264 4.2E-94 T 12-10-2018 IPR007035 Peptidase M55, D-aminopeptidase MIM_c21960 df7669938c264f719a85ad8b4c1eca32 180 Gene3D G3DSA:3.30.1330.60 26 147 2.3E-18 T 12-10-2018 IPR036737 OmpA-like domain superfamily MIM_c21960 df7669938c264f719a85ad8b4c1eca32 180 PRINTS PR01021 OMPA domain signature 97 113 1.1E-5 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MIM_c21960 df7669938c264f719a85ad8b4c1eca32 180 PRINTS PR01021 OMPA domain signature 52 74 1.1E-5 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MIM_c21960 df7669938c264f719a85ad8b4c1eca32 180 PRINTS PR01021 OMPA domain signature 82 97 1.1E-5 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MIM_c21960 df7669938c264f719a85ad8b4c1eca32 180 SUPERFAMILY SSF103088 38 132 1.83E-16 T 12-10-2018 IPR036737 OmpA-like domain superfamily MIM_c21960 df7669938c264f719a85ad8b4c1eca32 180 Pfam PF00691 OmpA family 52 126 9.1E-13 T 12-10-2018 IPR006665 OmpA-like domain MIM_c05230 d038ac75e02fa2d22e84005d5c7bd31e 689 SUPERFAMILY SSF53955 526 678 2.49E-43 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily MIM_c05230 d038ac75e02fa2d22e84005d5c7bd31e 689 Gene3D G3DSA:1.10.530.10 519 683 3.2E-40 T 12-10-2018 MIM_c05230 d038ac75e02fa2d22e84005d5c7bd31e 689 Gene3D G3DSA:1.25.20.10 77 434 1.6E-40 T 12-10-2018 MIM_c05230 d038ac75e02fa2d22e84005d5c7bd31e 689 SUPERFAMILY SSF48435 78 522 2.88E-77 T 12-10-2018 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 MIM_c05230 d038ac75e02fa2d22e84005d5c7bd31e 689 Pfam PF14718 Soluble lytic murein transglycosylase L domain 452 513 1.0E-9 T 12-10-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 MIM_c05230 d038ac75e02fa2d22e84005d5c7bd31e 689 Pfam PF01464 Transglycosylase SLT domain 532 638 5.3E-21 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 MIM_c31000 e145b4bd582316e222c6319f0d1094d1 298 PIRSF PIRSF000103 1 297 8.1E-62 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 MIM_c31000 e145b4bd582316e222c6319f0d1094d1 298 SUPERFAMILY SSF48179 169 295 5.78E-26 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c31000 e145b4bd582316e222c6319f0d1094d1 298 Gene3D G3DSA:3.40.50.720 1 168 1.1E-41 T 12-10-2018 MIM_c31000 e145b4bd582316e222c6319f0d1094d1 298 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 8 168 4.9E-33 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 MIM_c31000 e145b4bd582316e222c6319f0d1094d1 298 SUPERFAMILY SSF51735 8 168 7.45E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c31000 e145b4bd582316e222c6319f0d1094d1 298 Gene3D G3DSA:1.10.1040.10 169 297 9.6E-29 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MIM_c31000 e145b4bd582316e222c6319f0d1094d1 298 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 171 280 6.5E-24 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MIM_c35550 e39784312bdacd0701c925d6c5e0d793 234 SUPERFAMILY SSF48008 80 214 3.66E-24 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c35550 e39784312bdacd0701c925d6c5e0d793 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 71 1.7E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c35550 e39784312bdacd0701c925d6c5e0d793 234 SUPERFAMILY SSF46785 10 78 1.78E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c35550 e39784312bdacd0701c925d6c5e0d793 234 Pfam PF07729 FCD domain 85 206 1.3E-26 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c35550 e39784312bdacd0701c925d6c5e0d793 234 SMART SM00345 16 74 9.8E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c35550 e39784312bdacd0701c925d6c5e0d793 234 SMART SM00895 84 208 1.5E-17 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c35550 e39784312bdacd0701c925d6c5e0d793 234 Gene3D G3DSA:1.20.120.530 78 224 6.4E-28 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c35550 e39784312bdacd0701c925d6c5e0d793 234 Gene3D G3DSA:1.10.10.10 8 76 1.1E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c28150 a7048bc0ed2f95c4896f79149b0be12d 257 SUPERFAMILY SSF51735 7 255 5.41E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c28150 a7048bc0ed2f95c4896f79149b0be12d 257 Gene3D G3DSA:3.40.50.720 1 257 3.8E-67 T 12-10-2018 MIM_c28150 a7048bc0ed2f95c4896f79149b0be12d 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.2E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c28150 a7048bc0ed2f95c4896f79149b0be12d 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.2E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c28150 a7048bc0ed2f95c4896f79149b0be12d 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 2.2E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c28150 a7048bc0ed2f95c4896f79149b0be12d 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.2E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c28150 a7048bc0ed2f95c4896f79149b0be12d 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 2.2E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c28150 a7048bc0ed2f95c4896f79149b0be12d 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 255 1.3E-42 T 12-10-2018 MIM_c36400 967d62981eef578e4956fb35c92c1494 472 PIRSF PIRSF006060 1 471 2.8E-75 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MIM_c36400 967d62981eef578e4956fb35c92c1494 472 Pfam PF00324 Amino acid permease 17 457 1.6E-105 T 12-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 MIM_c36400 967d62981eef578e4956fb35c92c1494 472 ProSitePatterns PS00218 Amino acid permeases signature. 42 72 - T 12-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 MIM_c36400 967d62981eef578e4956fb35c92c1494 472 Gene3D G3DSA:1.20.1740.10 8 470 1.6E-68 T 12-10-2018 MIM_c07590 9f9ec21e6d7f0473c43807c37f2ea6fd 348 Gene3D G3DSA:1.10.10.60 287 341 1.5E-6 T 12-10-2018 MIM_c07590 9f9ec21e6d7f0473c43807c37f2ea6fd 348 Pfam PF02954 Bacterial regulatory protein, Fis family 296 320 1.2E-4 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MIM_c07590 9f9ec21e6d7f0473c43807c37f2ea6fd 348 SUPERFAMILY SSF46689 292 338 7.17E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c25980 1b84cb5aad95a8162df14e288ee68cde 446 SUPERFAMILY SSF53738 261 368 7.46E-29 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MIM_c25980 1b84cb5aad95a8162df14e288ee68cde 446 SUPERFAMILY SSF55957 359 441 1.7E-18 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MIM_c25980 1b84cb5aad95a8162df14e288ee68cde 446 SUPERFAMILY SSF53738 159 259 2.16E-29 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MIM_c25980 1b84cb5aad95a8162df14e288ee68cde 446 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 6 440 1.4E-175 T 12-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MIM_c25980 1b84cb5aad95a8162df14e288ee68cde 446 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 375 437 3.8E-14 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MIM_c25980 1b84cb5aad95a8162df14e288ee68cde 446 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 261 367 1.9E-29 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MIM_c25980 1b84cb5aad95a8162df14e288ee68cde 446 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 160 257 2.4E-18 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MIM_c25980 1b84cb5aad95a8162df14e288ee68cde 446 Gene3D G3DSA:3.40.120.10 177 364 1.4E-59 T 12-10-2018 MIM_c25980 1b84cb5aad95a8162df14e288ee68cde 446 SUPERFAMILY SSF53738 2 183 3.41E-47 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MIM_c25980 1b84cb5aad95a8162df14e288ee68cde 446 Gene3D G3DSA:3.30.310.50 372 444 2.8E-20 T 12-10-2018 MIM_c25980 1b84cb5aad95a8162df14e288ee68cde 446 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 137 5.3E-42 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MIM_c25980 1b84cb5aad95a8162df14e288ee68cde 446 Gene3D G3DSA:3.40.120.10 2 156 3.8E-47 T 12-10-2018 MIM_c25980 1b84cb5aad95a8162df14e288ee68cde 446 Gene3D G3DSA:3.40.120.10 260 341 1.4E-59 T 12-10-2018 MIM_c25980 1b84cb5aad95a8162df14e288ee68cde 446 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 98 112 5.3E-11 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MIM_c25980 1b84cb5aad95a8162df14e288ee68cde 446 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 237 252 5.3E-11 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MIM_c25980 1b84cb5aad95a8162df14e288ee68cde 446 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 177 196 5.3E-11 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MIM_c25980 1b84cb5aad95a8162df14e288ee68cde 446 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 2 446 45.027 T 12-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MIM_c37560 79e4281395ce12e568b7ccd33c236656 331 Gene3D G3DSA:3.40.190.150 37 321 2.4E-107 T 12-10-2018 MIM_c37560 79e4281395ce12e568b7ccd33c236656 331 SUPERFAMILY SSF53850 117 290 5.97E-9 T 12-10-2018 MIM_c37560 79e4281395ce12e568b7ccd33c236656 331 PIRSF PIRSF017082 1 331 5.7E-72 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c37560 79e4281395ce12e568b7ccd33c236656 331 Gene3D G3DSA:3.40.190.10 134 256 2.4E-107 T 12-10-2018 MIM_c37560 79e4281395ce12e568b7ccd33c236656 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 57 327 1.8E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c30540 57e749ab7b3b2ea47f4f9af71d83ca49 490 Gene3D G3DSA:2.30.40.10 5 433 1.6E-184 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MIM_c30540 57e749ab7b3b2ea47f4f9af71d83ca49 490 SUPERFAMILY SSF51556 59 420 2.38E-80 T 12-10-2018 IPR032466 Metal-dependent hydrolase MIM_c30540 57e749ab7b3b2ea47f4f9af71d83ca49 490 Pfam PF07969 Amidohydrolase family 47 224 1.2E-17 T 12-10-2018 IPR013108 Amidohydrolase 3 MIM_c30540 57e749ab7b3b2ea47f4f9af71d83ca49 490 Pfam PF07969 Amidohydrolase family 362 464 2.0E-13 T 12-10-2018 IPR013108 Amidohydrolase 3 MIM_c30540 57e749ab7b3b2ea47f4f9af71d83ca49 490 Gene3D G3DSA:3.20.20.140 58 415 1.6E-184 T 12-10-2018 MIM_c30540 57e749ab7b3b2ea47f4f9af71d83ca49 490 SUPERFAMILY SSF51338 6 482 1.97E-20 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MIM_c30540 57e749ab7b3b2ea47f4f9af71d83ca49 490 Gene3D G3DSA:3.30.1490.130 289 345 1.6E-184 T 12-10-2018 IPR023100 D-aminoacylase, insert domain superfamily GO:0016811 MIM_c07600 d2a066cd5313108a87af4c4d1ca9cbc8 357 Gene3D G3DSA:3.20.20.210 2 356 2.8E-148 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MIM_c07600 d2a066cd5313108a87af4c4d1ca9cbc8 357 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 143 159 - T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MIM_c07600 d2a066cd5313108a87af4c4d1ca9cbc8 357 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 8 352 48.428 T 12-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MIM_c07600 d2a066cd5313108a87af4c4d1ca9cbc8 357 SUPERFAMILY SSF51726 4 353 4.71E-112 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MIM_c07600 d2a066cd5313108a87af4c4d1ca9cbc8 357 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 7 351 4.3E-130 T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MIM_c07600 d2a066cd5313108a87af4c4d1ca9cbc8 357 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 11 350 6.3E-129 T 12-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MIM_c07600 d2a066cd5313108a87af4c4d1ca9cbc8 357 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 24 33 - T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MIM_c04320 24753e7860a474d684fc8448345d3da2 466 Pfam PF00330 Aconitase family (aconitate hydratase) 8 458 1.6E-135 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c04320 24753e7860a474d684fc8448345d3da2 466 SUPERFAMILY SSF53732 4 464 1.24E-143 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 MIM_c04320 24753e7860a474d684fc8448345d3da2 466 ProSitePatterns PS01244 Aconitase family signature 2. 400 413 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MIM_c04320 24753e7860a474d684fc8448345d3da2 466 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 3 463 1.6E-173 T 12-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 MIM_c04320 24753e7860a474d684fc8448345d3da2 466 PRINTS PR00415 Aconitase family signature 400 413 5.0E-37 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c04320 24753e7860a474d684fc8448345d3da2 466 PRINTS PR00415 Aconitase family signature 109 117 5.0E-37 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c04320 24753e7860a474d684fc8448345d3da2 466 PRINTS PR00415 Aconitase family signature 134 149 5.0E-37 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c04320 24753e7860a474d684fc8448345d3da2 466 PRINTS PR00415 Aconitase family signature 210 223 5.0E-37 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c04320 24753e7860a474d684fc8448345d3da2 466 PRINTS PR00415 Aconitase family signature 120 133 5.0E-37 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c04320 24753e7860a474d684fc8448345d3da2 466 PRINTS PR00415 Aconitase family signature 287 301 5.0E-37 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c04320 24753e7860a474d684fc8448345d3da2 466 PRINTS PR00415 Aconitase family signature 196 209 5.0E-37 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c04320 24753e7860a474d684fc8448345d3da2 466 PRINTS PR00415 Aconitase family signature 344 355 5.0E-37 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c04320 24753e7860a474d684fc8448345d3da2 466 Gene3D G3DSA:3.30.499.10 328 466 2.0E-45 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 MIM_c04320 24753e7860a474d684fc8448345d3da2 466 Gene3D G3DSA:3.30.499.20 5 286 2.9E-85 T 12-10-2018 MIM_c04320 24753e7860a474d684fc8448345d3da2 466 ProSitePatterns PS00450 Aconitase family signature 1. 340 356 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MIM_c28010 85e1d501156d74990a0e77d6b4502282 299 SMART SM00116 146 194 0.34 T 12-10-2018 IPR000644 CBS domain MIM_c28010 85e1d501156d74990a0e77d6b4502282 299 SMART SM00116 85 134 10.0 T 12-10-2018 IPR000644 CBS domain MIM_c28010 85e1d501156d74990a0e77d6b4502282 299 Pfam PF03471 Transporter associated domain 214 287 8.6E-21 T 12-10-2018 IPR005170 Transporter-associated domain MIM_c28010 85e1d501156d74990a0e77d6b4502282 299 Pfam PF00571 CBS domain 149 194 3.4E-5 T 12-10-2018 IPR000644 CBS domain MIM_c28010 85e1d501156d74990a0e77d6b4502282 299 Pfam PF00571 CBS domain 88 134 4.4E-6 T 12-10-2018 IPR000644 CBS domain MIM_c28010 85e1d501156d74990a0e77d6b4502282 299 SUPERFAMILY SSF56176 209 293 3.0E-21 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MIM_c28010 85e1d501156d74990a0e77d6b4502282 299 Gene3D G3DSA:3.30.465.10 208 289 2.0E-23 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MIM_c28010 85e1d501156d74990a0e77d6b4502282 299 SMART SM01091 210 288 4.6E-24 T 12-10-2018 IPR005170 Transporter-associated domain MIM_c28010 85e1d501156d74990a0e77d6b4502282 299 SUPERFAMILY SSF54631 71 209 2.27E-31 T 12-10-2018 MIM_c28010 85e1d501156d74990a0e77d6b4502282 299 Gene3D G3DSA:3.10.580.10 55 205 3.0E-53 T 12-10-2018 MIM_c30010 12b99a33bdbd06b5f65bc84f9a395a4b 277 Gene3D G3DSA:3.40.50.1820 1 272 2.5E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c30010 12b99a33bdbd06b5f65bc84f9a395a4b 277 SUPERFAMILY SSF53474 4 269 9.98E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c30010 12b99a33bdbd06b5f65bc84f9a395a4b 277 Pfam PF12697 Alpha/beta hydrolase family 31 265 2.4E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c08600 851676a50b01077576a093934d96c7af 314 SUPERFAMILY SSF51569 2 301 2.2E-60 T 12-10-2018 MIM_c08600 851676a50b01077576a093934d96c7af 314 Gene3D G3DSA:3.20.20.70 1 302 2.0E-97 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c08600 851676a50b01077576a093934d96c7af 314 Pfam PF00682 HMGL-like 4 282 5.3E-37 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 MIM_c10190 2872aaecfca7b4f05f22709baa9bb783 188 Gene3D G3DSA:1.10.150.20 67 138 4.1E-26 T 12-10-2018 MIM_c10190 2872aaecfca7b4f05f22709baa9bb783 188 SUPERFAMILY SSF46929 145 187 1.31E-8 T 12-10-2018 IPR036267 RuvA, C-terminal domain superfamily MIM_c10190 2872aaecfca7b4f05f22709baa9bb783 188 SMART SM00278 108 127 0.0029 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MIM_c10190 2872aaecfca7b4f05f22709baa9bb783 188 SMART SM00278 73 92 5.8 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MIM_c10190 2872aaecfca7b4f05f22709baa9bb783 188 SUPERFAMILY SSF47781 67 135 1.11E-20 T 12-10-2018 IPR010994 RuvA domain 2-like MIM_c10190 2872aaecfca7b4f05f22709baa9bb783 188 SUPERFAMILY SSF50249 1 63 6.28E-18 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c10190 2872aaecfca7b4f05f22709baa9bb783 188 Pfam PF14520 Helix-hairpin-helix domain 72 129 1.0E-17 T 12-10-2018 MIM_c10190 2872aaecfca7b4f05f22709baa9bb783 188 Pfam PF01330 RuvA N terminal domain 1 62 6.1E-20 T 12-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 MIM_c10190 2872aaecfca7b4f05f22709baa9bb783 188 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 187 31.16 T 12-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 MIM_c10190 2872aaecfca7b4f05f22709baa9bb783 188 Gene3D G3DSA:1.10.8.10 142 186 1.2E-6 T 12-10-2018 MIM_c10190 2872aaecfca7b4f05f22709baa9bb783 188 Gene3D G3DSA:2.40.50.140 1 66 3.1E-26 T 12-10-2018 MIM_c10190 2872aaecfca7b4f05f22709baa9bb783 188 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 186 2.2E-54 T 12-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 MIM_c10190 2872aaecfca7b4f05f22709baa9bb783 188 Pfam PF07499 RuvA, C-terminal domain 145 187 2.1E-12 T 12-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 MIM_c39940 d9e3a5d947b519ed805d0c1e66a3d9e7 477 Gene3D G3DSA:3.30.1490.270 348 408 1.7E-24 T 12-10-2018 MIM_c39940 d9e3a5d947b519ed805d0c1e66a3d9e7 477 Gene3D G3DSA:3.40.50.11290 214 311 2.8E-42 T 12-10-2018 MIM_c39940 d9e3a5d947b519ed805d0c1e66a3d9e7 477 PIRSF PIRSF005522 1 477 7.9E-228 T 12-10-2018 IPR016450 Uncharacterised conserved protein UCP005522 MIM_c39940 d9e3a5d947b519ed805d0c1e66a3d9e7 477 Pfam PF14403 Circularly permuted ATP-grasp type 2 76 451 2.5E-159 T 12-10-2018 IPR025841 Circularly permuted ATP-grasp type 2 MIM_c39940 d9e3a5d947b519ed805d0c1e66a3d9e7 477 SUPERFAMILY SSF56059 20 466 6.96E-66 T 12-10-2018 MIM_c27570 27043a726312a40bd6b307301eb92f1a 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 320 3.6E-69 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c27570 27043a726312a40bd6b307301eb92f1a 324 Gene3D G3DSA:3.40.190.150 27 312 1.4E-88 T 12-10-2018 MIM_c27570 27043a726312a40bd6b307301eb92f1a 324 PIRSF PIRSF017082 1 323 1.3E-63 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c27570 27043a726312a40bd6b307301eb92f1a 324 SUPERFAMILY SSF53850 112 291 1.59E-16 T 12-10-2018 MIM_c27570 27043a726312a40bd6b307301eb92f1a 324 Gene3D G3DSA:3.40.190.10 125 249 1.4E-88 T 12-10-2018 MIM_c11780 590b11af79677e73593c5f2672cbd4d5 244 Gene3D G3DSA:3.30.1370.110 126 244 8.4E-32 T 12-10-2018 MIM_c11780 590b11af79677e73593c5f2672cbd4d5 244 Pfam PF01713 Smr domain 158 239 1.1E-19 T 12-10-2018 IPR002625 Smr domain MIM_c11780 590b11af79677e73593c5f2672cbd4d5 244 SUPERFAMILY SSF160443 156 239 1.83E-15 T 12-10-2018 IPR036063 Smr domain superfamily MIM_c11780 590b11af79677e73593c5f2672cbd4d5 244 SMART SM00463 155 239 7.1E-9 T 12-10-2018 IPR002625 Smr domain MIM_c29970 3484d6f60f009999f9d5d4aab7a761ed 404 Pfam PF13103 TonB C terminal 321 393 2.7E-8 T 12-10-2018 MIM_c29970 3484d6f60f009999f9d5d4aab7a761ed 404 TIGRFAM TIGR02794 tolA_full: protein TolA 18 239 7.5E-21 T 12-10-2018 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0016021|GO:0043213 MIM_c29970 3484d6f60f009999f9d5d4aab7a761ed 404 TIGRFAM TIGR02794 tolA_full: protein TolA 212 390 1.5E-26 T 12-10-2018 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0016021|GO:0043213 MIM_c29970 3484d6f60f009999f9d5d4aab7a761ed 404 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 344 404 8.3E-9 T 12-10-2018 IPR006260 TonB/TolA, C-terminal MIM_c29970 3484d6f60f009999f9d5d4aab7a761ed 404 SUPERFAMILY SSF74653 321 401 1.29E-9 T 12-10-2018 MIM_c16650 ef69effc6bfd5182c626cfb4cf8e688c 454 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 29 279 2.8E-72 T 12-10-2018 IPR017039 Virulence factor BrkB MIM_c16650 ef69effc6bfd5182c626cfb4cf8e688c 454 Hamap MF_00672 UPF0761 membrane protein YihY [yihY]. 7 311 22.752 T 12-10-2018 IPR023679 Uncharacterised protein family UPF0761, bacterial MIM_c16650 ef69effc6bfd5182c626cfb4cf8e688c 454 Pfam PF03631 Virulence factor BrkB 34 280 9.0E-58 T 12-10-2018 IPR017039 Virulence factor BrkB MIM_c14270 0adf5ca8162261385f10eb3a049fc959 252 SUPERFAMILY SSF48613 20 244 1.36E-70 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 MIM_c14270 0adf5ca8162261385f10eb3a049fc959 252 Hamap MF_00654 Pyrroloquinoline-quinone synthase [pqqC]. 1 252 126.974 T 12-10-2018 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420 MIM_c14270 0adf5ca8162261385f10eb3a049fc959 252 Pfam PF03070 TENA/THI-4/PQQC family 28 237 2.8E-53 T 12-10-2018 IPR004305 Thiaminase-2/PQQC MIM_c14270 0adf5ca8162261385f10eb3a049fc959 252 TIGRFAM TIGR02111 PQQ_syn_pqqC: coenzyme PQQ biosynthesis protein C 22 245 3.2E-99 T 12-10-2018 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420 MIM_c14270 0adf5ca8162261385f10eb3a049fc959 252 Gene3D G3DSA:1.20.910.10 18 252 1.0E-68 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 MIM_c09270 911b7d0377920735229afed0dcda985a 319 PIRSF PIRSF000441 133 305 5.0E-51 T 12-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 MIM_c09270 911b7d0377920735229afed0dcda985a 319 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 204 240 8.8E-4 T 12-10-2018 IPR001451 Hexapeptide repeat MIM_c09270 911b7d0377920735229afed0dcda985a 319 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 259 293 6.4E-6 T 12-10-2018 IPR001451 Hexapeptide repeat MIM_c09270 911b7d0377920735229afed0dcda985a 319 SUPERFAMILY SSF51161 108 302 1.94E-44 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily MIM_c09270 911b7d0377920735229afed0dcda985a 319 Gene3D G3DSA:1.10.3130.10 45 199 8.1E-46 T 12-10-2018 MIM_c09270 911b7d0377920735229afed0dcda985a 319 Gene3D G3DSA:2.160.10.10 200 313 2.8E-33 T 12-10-2018 MIM_c31180 8a7e73be6c0e2d17c0adbfdaf70839c7 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 142 2.2E-26 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MIM_c31180 8a7e73be6c0e2d17c0adbfdaf70839c7 349 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 178 205 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 MIM_c31180 8a7e73be6c0e2d17c0adbfdaf70839c7 349 SUPERFAMILY SSF51735 151 312 1.25E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c31180 8a7e73be6c0e2d17c0adbfdaf70839c7 349 Gene3D G3DSA:3.90.180.10 14 342 1.4E-132 T 12-10-2018 MIM_c31180 8a7e73be6c0e2d17c0adbfdaf70839c7 349 SMART SM00829 11 342 2.3E-4 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MIM_c31180 8a7e73be6c0e2d17c0adbfdaf70839c7 349 Pfam PF00107 Zinc-binding dehydrogenase 185 308 3.5E-25 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MIM_c31180 8a7e73be6c0e2d17c0adbfdaf70839c7 349 SUPERFAMILY SSF50129 8 172 7.61E-47 T 12-10-2018 IPR011032 GroES-like superfamily MIM_c31180 8a7e73be6c0e2d17c0adbfdaf70839c7 349 Gene3D G3DSA:3.40.50.720 159 314 1.4E-132 T 12-10-2018 MIM_c31180 8a7e73be6c0e2d17c0adbfdaf70839c7 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MIM_c21750 3183131493c034dd9aed140e64ac3863 228 SUPERFAMILY SSF88946 10 114 1.79E-25 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MIM_c21750 3183131493c034dd9aed140e64ac3863 228 Pfam PF04542 Sigma-70 region 2 35 101 3.4E-12 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MIM_c21750 3183131493c034dd9aed140e64ac3863 228 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 194 1.8E-25 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MIM_c21750 3183131493c034dd9aed140e64ac3863 228 SUPERFAMILY SSF88659 118 196 5.61E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MIM_c21750 3183131493c034dd9aed140e64ac3863 228 Gene3D G3DSA:1.10.10.10 124 199 1.8E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c21750 3183131493c034dd9aed140e64ac3863 228 Pfam PF08281 Sigma-70, region 4 139 186 2.0E-11 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MIM_c21750 3183131493c034dd9aed140e64ac3863 228 Gene3D G3DSA:1.10.1740.10 10 123 3.1E-26 T 12-10-2018 MIM_c22850 21e9b684e9e7adebe8045c86d2467a11 377 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 3 376 48.001 T 12-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 MIM_c22850 21e9b684e9e7adebe8045c86d2467a11 377 PIRSF PIRSF000525 1 377 7.0E-140 T 12-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 MIM_c22850 21e9b684e9e7adebe8045c86d2467a11 377 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 204 223 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MIM_c22850 21e9b684e9e7adebe8045c86d2467a11 377 Gene3D G3DSA:3.90.1150.10 268 377 6.2E-43 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c22850 21e9b684e9e7adebe8045c86d2467a11 377 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 6 376 4.4E-142 T 12-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 MIM_c22850 21e9b684e9e7adebe8045c86d2467a11 377 Gene3D G3DSA:3.40.640.10 18 267 1.9E-82 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c22850 21e9b684e9e7adebe8045c86d2467a11 377 Pfam PF00266 Aminotransferase class-V 6 364 1.6E-49 T 12-10-2018 IPR000192 Aminotransferase class V domain MIM_c22850 21e9b684e9e7adebe8045c86d2467a11 377 SUPERFAMILY SSF53383 5 375 2.13E-108 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c34860 974f685e7054ec0ca9bf1053da46632a 560 SUPERFAMILY SSF52540 293 530 2.25E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c34860 974f685e7054ec0ca9bf1053da46632a 560 SMART SM00382 309 508 3.5E-20 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c34860 974f685e7054ec0ca9bf1053da46632a 560 SMART SM00382 30 226 1.2E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c34860 974f685e7054ec0ca9bf1053da46632a 560 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c34860 974f685e7054ec0ca9bf1053da46632a 560 SUPERFAMILY SSF52540 5 249 1.42E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c34860 974f685e7054ec0ca9bf1053da46632a 560 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 510 539 0.0014 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c34860 974f685e7054ec0ca9bf1053da46632a 560 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 229 256 3.4E-5 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c34860 974f685e7054ec0ca9bf1053da46632a 560 Pfam PF00005 ABC transporter 301 459 7.8E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c34860 974f685e7054ec0ca9bf1053da46632a 560 Gene3D G3DSA:3.40.50.300 4 271 8.7E-79 T 12-10-2018 MIM_c34860 974f685e7054ec0ca9bf1053da46632a 560 Gene3D G3DSA:3.40.50.300 272 555 5.7E-77 T 12-10-2018 MIM_c34860 974f685e7054ec0ca9bf1053da46632a 560 ProSitePatterns PS00211 ABC transporters family signature. 431 445 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c34860 974f685e7054ec0ca9bf1053da46632a 560 Pfam PF00005 ABC transporter 22 177 1.9E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c29570 5c1ca6b0c89f689857ff2d983d04a53b 193 SUPERFAMILY SSF143456 13 193 6.67E-58 T 12-10-2018 MIM_c29570 5c1ca6b0c89f689857ff2d983d04a53b 193 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 13 193 35.837 T 12-10-2018 IPR003774 Protein of unknown function UPF0301 MIM_c29570 5c1ca6b0c89f689857ff2d983d04a53b 193 Pfam PF02622 Uncharacterized ACR, COG1678 27 180 1.5E-43 T 12-10-2018 IPR003774 Protein of unknown function UPF0301 MIM_c29570 5c1ca6b0c89f689857ff2d983d04a53b 193 Gene3D G3DSA:3.40.1740.10 8 193 5.9E-64 T 12-10-2018 MIM_c01140 2d7284d8455e54bacb61f58ce0d2bc5e 416 SUPERFAMILY SSF53822 30 403 2.59E-75 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c01140 2d7284d8455e54bacb61f58ce0d2bc5e 416 Gene3D G3DSA:3.40.50.2300 32 359 1.1E-79 T 12-10-2018 MIM_c01140 2d7284d8455e54bacb61f58ce0d2bc5e 416 Pfam PF13458 Periplasmic binding protein 30 389 2.9E-62 T 12-10-2018 IPR028081 Leucine-binding protein domain MIM_c01140 2d7284d8455e54bacb61f58ce0d2bc5e 416 Gene3D G3DSA:3.40.50.2300 155 291 1.1E-79 T 12-10-2018 MIM_c22930 edaa3f7c205d2ae06dfa652c64358632 322 SUPERFAMILY SSF51735 1 311 6.65E-88 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c22930 edaa3f7c205d2ae06dfa652c64358632 322 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 309 1.4E-92 T 12-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 MIM_c22930 edaa3f7c205d2ae06dfa652c64358632 322 Gene3D G3DSA:3.40.50.720 3 298 4.6E-103 T 12-10-2018 MIM_c22930 edaa3f7c205d2ae06dfa652c64358632 322 Pfam PF04321 RmlD substrate binding domain 1 311 1.4E-94 T 12-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 MIM_c22930 edaa3f7c205d2ae06dfa652c64358632 322 Gene3D G3DSA:3.90.25.10 178 305 4.6E-103 T 12-10-2018 MIM_c31520 2d53a32761dc2bad5d5563859ff317ed 567 Pfam PF07731 Multicopper oxidase 452 564 8.4E-24 T 12-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 MIM_c31520 2d53a32761dc2bad5d5563859ff317ed 567 SUPERFAMILY SSF49503 444 563 1.1E-26 T 12-10-2018 IPR008972 Cupredoxin MIM_c31520 2d53a32761dc2bad5d5563859ff317ed 567 Pfam PF07732 Multicopper oxidase 60 167 8.0E-31 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 MIM_c31520 2d53a32761dc2bad5d5563859ff317ed 567 Gene3D G3DSA:2.60.40.420 30 169 1.1E-40 T 12-10-2018 IPR008972 Cupredoxin MIM_c31520 2d53a32761dc2bad5d5563859ff317ed 567 Gene3D G3DSA:2.60.40.420 393 565 2.3E-42 T 12-10-2018 IPR008972 Cupredoxin MIM_c31520 2d53a32761dc2bad5d5563859ff317ed 567 SUPERFAMILY SSF49503 173 291 4.07E-28 T 12-10-2018 IPR008972 Cupredoxin MIM_c31520 2d53a32761dc2bad5d5563859ff317ed 567 ProSitePatterns PS00080 Multicopper oxidases signature 2. 546 557 - T 12-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 MIM_c31520 2d53a32761dc2bad5d5563859ff317ed 567 SUPERFAMILY SSF49503 61 168 1.61E-29 T 12-10-2018 IPR008972 Cupredoxin MIM_c31520 2d53a32761dc2bad5d5563859ff317ed 567 Gene3D G3DSA:2.60.40.420 170 344 3.0E-42 T 12-10-2018 IPR008972 Cupredoxin MIM_c31520 2d53a32761dc2bad5d5563859ff317ed 567 Pfam PF00394 Multicopper oxidase 232 290 4.2E-5 T 12-10-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 MIM_c24450 5ee1f35645f47a74d7b49f98bfd495bf 169 Pfam PF10993 Protein of unknown function (DUF2818) 6 71 4.7E-6 T 12-10-2018 IPR016768 Uncharacterised conserved protein UCP019883, membrane MIM_c24450 5ee1f35645f47a74d7b49f98bfd495bf 169 Pfam PF10993 Protein of unknown function (DUF2818) 93 160 2.1E-20 T 12-10-2018 IPR016768 Uncharacterised conserved protein UCP019883, membrane MIM_c15970 85cc0dc7b245a70ee853cbe509410f7e 405 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 187 367 3.5E-67 T 12-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MIM_c15970 85cc0dc7b245a70ee853cbe509410f7e 405 SUPERFAMILY SSF102645 172 395 4.05E-72 T 12-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MIM_c15970 85cc0dc7b245a70ee853cbe509410f7e 405 Gene3D G3DSA:3.40.50.10300 187 399 4.2E-72 T 12-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MIM_c15970 85cc0dc7b245a70ee853cbe509410f7e 405 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 5 392 1.9E-132 T 12-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 MIM_c15970 85cc0dc7b245a70ee853cbe509410f7e 405 Pfam PF02441 Flavoprotein 7 177 1.3E-43 T 12-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 MIM_c15970 85cc0dc7b245a70ee853cbe509410f7e 405 Gene3D G3DSA:3.40.50.1950 1 186 5.0E-58 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 MIM_c15970 85cc0dc7b245a70ee853cbe509410f7e 405 SUPERFAMILY SSF52507 1 183 1.96E-62 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 MIM_c28620 947885fc162d66ab462c0890c968f932 117 TIGRFAM TIGR01244 TIGR01244: TIGR01244 family protein 7 110 5.7E-32 T 12-10-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 MIM_c28620 947885fc162d66ab462c0890c968f932 117 Pfam PF04273 Putative phosphatase (DUF442) 7 111 1.2E-32 T 12-10-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 MIM_c28620 947885fc162d66ab462c0890c968f932 117 Gene3D G3DSA:3.90.190.10 2 117 6.1E-30 T 12-10-2018 IPR029021 Protein-tyrosine phosphatase-like MIM_c02220 2e11f5308bc934525589d7fb99d8c612 252 Gene3D G3DSA:3.40.50.300 1 251 9.7E-67 T 12-10-2018 MIM_c02220 2e11f5308bc934525589d7fb99d8c612 252 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c02220 2e11f5308bc934525589d7fb99d8c612 252 Pfam PF00005 ABC transporter 18 164 6.9E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c02220 2e11f5308bc934525589d7fb99d8c612 252 SUPERFAMILY SSF52540 2 227 4.26E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c02220 2e11f5308bc934525589d7fb99d8c612 252 SMART SM00382 26 213 3.2E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c21910 c4ccceab3ea71f208481d599ed38b133 89 Gene3D G3DSA:3.30.1340.10 1 88 1.5E-32 T 12-10-2018 IPR035895 HPr-like superfamily MIM_c21910 c4ccceab3ea71f208481d599ed38b133 89 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 5.4E-31 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like MIM_c21910 c4ccceab3ea71f208481d599ed38b133 89 SUPERFAMILY SSF55594 4 87 2.49E-28 T 12-10-2018 IPR035895 HPr-like superfamily MIM_c21910 c4ccceab3ea71f208481d599ed38b133 89 Pfam PF00381 PTS HPr component phosphorylation site 5 82 2.2E-28 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like MIM_c21910 c4ccceab3ea71f208481d599ed38b133 89 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 12-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site MIM_c21910 c4ccceab3ea71f208481d599ed38b133 89 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 12-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site MIM_c21910 c4ccceab3ea71f208481d599ed38b133 89 PRINTS PR00107 Phosphocarrier protein signature 13 29 1.8E-16 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like MIM_c21910 c4ccceab3ea71f208481d599ed38b133 89 PRINTS PR00107 Phosphocarrier protein signature 53 70 1.8E-16 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like MIM_c21910 c4ccceab3ea71f208481d599ed38b133 89 PRINTS PR00107 Phosphocarrier protein signature 38 53 1.8E-16 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like MIM_c22470 a08a7a6398b6370131bf82709d7b1068 284 SUPERFAMILY SSF103088 156 274 3.92E-24 T 12-10-2018 IPR036737 OmpA-like domain superfamily MIM_c22470 a08a7a6398b6370131bf82709d7b1068 284 Pfam PF04355 SmpA / OmlA family 56 128 2.2E-19 T 12-10-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 MIM_c22470 a08a7a6398b6370131bf82709d7b1068 284 Gene3D G3DSA:3.30.1330.60 144 280 4.1E-32 T 12-10-2018 IPR036737 OmpA-like domain superfamily MIM_c22470 a08a7a6398b6370131bf82709d7b1068 284 Gene3D G3DSA:3.30.1450.10 55 138 2.8E-10 T 12-10-2018 IPR037873 BamE-like MIM_c22470 a08a7a6398b6370131bf82709d7b1068 284 ProSitePatterns PS01068 OmpA-like domain. 199 243 - T 12-10-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 MIM_c22470 a08a7a6398b6370131bf82709d7b1068 284 Pfam PF00691 OmpA family 163 254 1.5E-15 T 12-10-2018 IPR006665 OmpA-like domain MIM_c28890 19502708a44d2e86cc186313ae6f6729 615 Gene3D G3DSA:1.20.1530.20 7 390 3.7E-81 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily MIM_c28890 19502708a44d2e86cc186313ae6f6729 615 Gene3D G3DSA:3.40.50.720 405 565 3.2E-33 T 12-10-2018 MIM_c28890 19502708a44d2e86cc186313ae6f6729 615 Pfam PF02254 TrkA-N domain 408 520 7.0E-20 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MIM_c28890 19502708a44d2e86cc186313ae6f6729 615 SUPERFAMILY SSF51735 406 535 1.25E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c28890 19502708a44d2e86cc186313ae6f6729 615 PRINTS PR00335 TrkA potassium uptake protein signature 463 473 2.4E-7 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MIM_c28890 19502708a44d2e86cc186313ae6f6729 615 PRINTS PR00335 TrkA potassium uptake protein signature 452 462 2.4E-7 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MIM_c28890 19502708a44d2e86cc186313ae6f6729 615 PRINTS PR00335 TrkA potassium uptake protein signature 406 420 2.4E-7 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MIM_c28890 19502708a44d2e86cc186313ae6f6729 615 PRINTS PR00335 TrkA potassium uptake protein signature 423 437 2.4E-7 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MIM_c28890 19502708a44d2e86cc186313ae6f6729 615 Pfam PF00999 Sodium/hydrogen exchanger family 15 376 4.2E-67 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MIM_c28890 19502708a44d2e86cc186313ae6f6729 615 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 17 289 7.1E-76 T 12-10-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 MIM_c04530 080ae9542e11920ff6fa1dd8176e76e3 272 SUPERFAMILY SSF81464 28 122 7.85E-26 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c04530 080ae9542e11920ff6fa1dd8176e76e3 272 PRINTS PR01166 Cytochrome c oxidase subunit II signature 218 235 5.5E-38 T 12-10-2018 MIM_c04530 080ae9542e11920ff6fa1dd8176e76e3 272 PRINTS PR01166 Cytochrome c oxidase subunit II signature 90 102 5.5E-38 T 12-10-2018 MIM_c04530 080ae9542e11920ff6fa1dd8176e76e3 272 PRINTS PR01166 Cytochrome c oxidase subunit II signature 124 143 5.5E-38 T 12-10-2018 MIM_c04530 080ae9542e11920ff6fa1dd8176e76e3 272 PRINTS PR01166 Cytochrome c oxidase subunit II signature 174 195 5.5E-38 T 12-10-2018 MIM_c04530 080ae9542e11920ff6fa1dd8176e76e3 272 PRINTS PR01166 Cytochrome c oxidase subunit II signature 236 253 5.5E-38 T 12-10-2018 MIM_c04530 080ae9542e11920ff6fa1dd8176e76e3 272 PRINTS PR01166 Cytochrome c oxidase subunit II signature 198 218 5.5E-38 T 12-10-2018 MIM_c04530 080ae9542e11920ff6fa1dd8176e76e3 272 PRINTS PR01166 Cytochrome c oxidase subunit II signature 102 122 5.5E-38 T 12-10-2018 MIM_c04530 080ae9542e11920ff6fa1dd8176e76e3 272 Gene3D G3DSA:2.60.40.420 124 263 3.4E-80 T 12-10-2018 IPR008972 Cupredoxin MIM_c04530 080ae9542e11920ff6fa1dd8176e76e3 272 Gene3D G3DSA:1.10.287.90 52 123 3.4E-80 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c04530 080ae9542e11920ff6fa1dd8176e76e3 272 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 31 113 4.8E-14 T 12-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c04530 080ae9542e11920ff6fa1dd8176e76e3 272 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 42 263 4.2E-61 T 12-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c04530 080ae9542e11920ff6fa1dd8176e76e3 272 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 199 247 - T 12-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c04530 080ae9542e11920ff6fa1dd8176e76e3 272 SUPERFAMILY SSF49503 126 268 1.64E-53 T 12-10-2018 IPR008972 Cupredoxin MIM_c04530 080ae9542e11920ff6fa1dd8176e76e3 272 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 128 254 2.7E-39 T 12-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c10940 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 174 192 2.9E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c10940 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 106 119 2.9E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c10940 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 232 245 2.9E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c10940 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 SUPERFAMILY SSF56672 60 394 1.65E-56 T 12-10-2018 MIM_c10940 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 Pfam PF08388 Group II intron, maturase-specific domain 336 406 1.5E-16 T 12-10-2018 IPR013597 Group II intron, maturase-specific MIM_c10940 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 111 317 9.5E-45 T 12-10-2018 IPR000477 Reverse transcriptase domain MIM_c10940 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 55 400 1.5E-125 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase MIM_c24610 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 174 192 2.9E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c24610 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 106 119 2.9E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c24610 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 232 245 2.9E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c24610 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 SUPERFAMILY SSF56672 60 394 1.65E-56 T 12-10-2018 MIM_c24610 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 Pfam PF08388 Group II intron, maturase-specific domain 336 406 1.5E-16 T 12-10-2018 IPR013597 Group II intron, maturase-specific MIM_c24610 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 111 317 9.5E-45 T 12-10-2018 IPR000477 Reverse transcriptase domain MIM_c24610 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 55 400 1.5E-125 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase MIM_c40600 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 174 192 2.9E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c40600 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 106 119 2.9E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c40600 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 232 245 2.9E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c40600 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 SUPERFAMILY SSF56672 60 394 1.65E-56 T 12-10-2018 MIM_c40600 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 Pfam PF08388 Group II intron, maturase-specific domain 336 406 1.5E-16 T 12-10-2018 IPR013597 Group II intron, maturase-specific MIM_c40600 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 111 317 9.5E-45 T 12-10-2018 IPR000477 Reverse transcriptase domain MIM_c40600 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 55 400 1.5E-125 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase MIM_c32600 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 174 192 2.9E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c32600 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 106 119 2.9E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c32600 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 232 245 2.9E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c32600 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 SUPERFAMILY SSF56672 60 394 1.65E-56 T 12-10-2018 MIM_c32600 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 Pfam PF08388 Group II intron, maturase-specific domain 336 406 1.5E-16 T 12-10-2018 IPR013597 Group II intron, maturase-specific MIM_c32600 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 111 317 9.5E-45 T 12-10-2018 IPR000477 Reverse transcriptase domain MIM_c32600 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 55 400 1.5E-125 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase MIM_c10840 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 174 192 2.9E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c10840 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 106 119 2.9E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c10840 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 232 245 2.9E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c10840 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 SUPERFAMILY SSF56672 60 394 1.65E-56 T 12-10-2018 MIM_c10840 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 Pfam PF08388 Group II intron, maturase-specific domain 336 406 1.5E-16 T 12-10-2018 IPR013597 Group II intron, maturase-specific MIM_c10840 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 111 317 9.5E-45 T 12-10-2018 IPR000477 Reverse transcriptase domain MIM_c10840 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 55 400 1.5E-125 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase MIM_c21980 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 174 192 2.9E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c21980 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 106 119 2.9E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c21980 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 232 245 2.9E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c21980 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 SUPERFAMILY SSF56672 60 394 1.65E-56 T 12-10-2018 MIM_c21980 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 Pfam PF08388 Group II intron, maturase-specific domain 336 406 1.5E-16 T 12-10-2018 IPR013597 Group II intron, maturase-specific MIM_c21980 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 111 317 9.5E-45 T 12-10-2018 IPR000477 Reverse transcriptase domain MIM_c21980 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 55 400 1.5E-125 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase MIM_c15640 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 174 192 2.9E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c15640 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 106 119 2.9E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c15640 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 232 245 2.9E-7 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c15640 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 SUPERFAMILY SSF56672 60 394 1.65E-56 T 12-10-2018 MIM_c15640 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 Pfam PF08388 Group II intron, maturase-specific domain 336 406 1.5E-16 T 12-10-2018 IPR013597 Group II intron, maturase-specific MIM_c15640 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 111 317 9.5E-45 T 12-10-2018 IPR000477 Reverse transcriptase domain MIM_c15640 3eb94c8ec36a6d3c37b7ce57d6047f6d 456 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 55 400 1.5E-125 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase MIM_c14840 e7ba807ebd4558e7c7c6a1bcc837a535 112 SUPERFAMILY SSF50249 1 100 1.06E-14 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c14840 e7ba807ebd4558e7c7c6a1bcc837a535 112 Gene3D G3DSA:2.40.50.140 1 105 4.5E-33 T 12-10-2018 MIM_c14840 e7ba807ebd4558e7c7c6a1bcc837a535 112 TIGRFAM TIGR04418 PriB_gamma: primosomal replication protein PriB 2 95 1.7E-29 T 12-10-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 MIM_c14840 e7ba807ebd4558e7c7c6a1bcc837a535 112 PIRSF PIRSF003135 1 96 1.4E-15 T 12-10-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 MIM_c14840 e7ba807ebd4558e7c7c6a1bcc837a535 112 Hamap MF_00720 Primosomal replication protein N [priB]. 1 96 22.779 T 12-10-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 MIM_c08200 c53da32e869317e93b062e1288d00f3f 458 Pfam PF07005 Putative sugar-binding N-terminal domain 6 253 2.9E-43 T 12-10-2018 IPR010737 Four-carbon acid sugar kinase, N-terminal domain MIM_c08200 c53da32e869317e93b062e1288d00f3f 458 SUPERFAMILY SSF142764 6 448 2.09E-71 T 12-10-2018 MIM_c08200 c53da32e869317e93b062e1288d00f3f 458 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 286 443 5.4E-24 T 12-10-2018 IPR031475 Four-carbon acid sugar kinase, C-terminal domain MIM_c08200 c53da32e869317e93b062e1288d00f3f 458 Gene3D G3DSA:3.40.50.10840 3 263 4.9E-57 T 12-10-2018 IPR037051 Four-carbon acid sugar kinase, N-terminal domain superfamily MIM_c08200 c53da32e869317e93b062e1288d00f3f 458 Gene3D G3DSA:3.40.980.20 271 450 1.6E-30 T 12-10-2018 MIM_c06760 98256dd649c95367f1580589f6798696 289 Gene3D G3DSA:3.30.470.10 4 127 8.8E-35 T 12-10-2018 MIM_c06760 98256dd649c95367f1580589f6798696 289 Pfam PF01063 Amino-transferase class IV 38 260 1.3E-36 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 MIM_c06760 98256dd649c95367f1580589f6798696 289 SUPERFAMILY SSF56752 11 283 4.84E-73 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 MIM_c06760 98256dd649c95367f1580589f6798696 289 Gene3D G3DSA:3.20.10.10 128 288 1.8E-51 T 12-10-2018 MIM_c18410 dadcd46bf26833413157c46e9e2f8e53 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 106 2.3E-37 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MIM_c18410 dadcd46bf26833413157c46e9e2f8e53 108 Gene3D G3DSA:3.40.30.10 4 108 2.0E-36 T 12-10-2018 MIM_c18410 dadcd46bf26833413157c46e9e2f8e53 108 PRINTS PR00421 Thioredoxin family signature 32 41 4.5E-10 T 12-10-2018 MIM_c18410 dadcd46bf26833413157c46e9e2f8e53 108 PRINTS PR00421 Thioredoxin family signature 72 83 4.5E-10 T 12-10-2018 MIM_c18410 dadcd46bf26833413157c46e9e2f8e53 108 PRINTS PR00421 Thioredoxin family signature 24 32 4.5E-10 T 12-10-2018 MIM_c18410 dadcd46bf26833413157c46e9e2f8e53 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MIM_c18410 dadcd46bf26833413157c46e9e2f8e53 108 PIRSF PIRSF000077 2 108 1.6E-40 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MIM_c18410 dadcd46bf26833413157c46e9e2f8e53 108 Pfam PF00085 Thioredoxin 6 106 4.4E-34 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 MIM_c18410 dadcd46bf26833413157c46e9e2f8e53 108 SUPERFAMILY SSF52833 5 106 3.66E-39 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c14380 ed7a2dc8f8d321b82ee292bf60797474 495 Gene3D G3DSA:3.30.70.150 34 160 6.8E-50 T 12-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 MIM_c14380 ed7a2dc8f8d321b82ee292bf60797474 495 SUPERFAMILY SSF54966 21 160 8.11E-58 T 12-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 MIM_c14380 ed7a2dc8f8d321b82ee292bf60797474 495 Gene3D G3DSA:3.20.20.110 162 491 4.2E-137 T 12-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 MIM_c14380 ed7a2dc8f8d321b82ee292bf60797474 495 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 166 473 7.4E-133 T 12-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 MIM_c14380 ed7a2dc8f8d321b82ee292bf60797474 495 Hamap MF_01338 Ribulose bisphosphate carboxylase large chain [rbcL]. 20 486 55.456 T 12-10-2018 IPR020888 Ribulose bisphosphate carboxylase large subunit, type I GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 MIM_c14380 ed7a2dc8f8d321b82ee292bf60797474 495 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 36 156 6.4E-45 T 12-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 MIM_c14380 ed7a2dc8f8d321b82ee292bf60797474 495 ProSitePatterns PS00157 Ribulose bisphosphate carboxylase large chain active site. 208 216 - T 12-10-2018 IPR020878 Ribulose bisphosphate carboxylase, large chain, active site GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 MIM_c14380 ed7a2dc8f8d321b82ee292bf60797474 495 SUPERFAMILY SSF51649 162 488 4.32E-144 T 12-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 MIM_c15000 58cdc2da50b4109e0c9236ff16f00e5e 281 TIGRFAM TIGR03464 HpnC: squalene synthase HpnC 2 274 2.0E-97 T 12-10-2018 IPR017827 Hydroxysqualene synthase HpnC MetaCyc: PWY-7072 MIM_c15000 58cdc2da50b4109e0c9236ff16f00e5e 281 Gene3D G3DSA:1.10.600.10 1 255 5.7E-69 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily MIM_c15000 58cdc2da50b4109e0c9236ff16f00e5e 281 SUPERFAMILY SSF48576 4 277 7.34E-63 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily MIM_c15000 58cdc2da50b4109e0c9236ff16f00e5e 281 Pfam PF00494 Squalene/phytoene synthase 5 263 8.6E-54 T 12-10-2018 MIM_c05870 f5ab5297508449cdd5d5d01066cbd8e6 289 SUPERFAMILY SSF53697 99 266 1.48E-25 T 12-10-2018 MIM_c05870 f5ab5297508449cdd5d5d01066cbd8e6 289 Pfam PF01380 SIS domain 131 253 7.2E-19 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MIM_c05870 f5ab5297508449cdd5d5d01066cbd8e6 289 SUPERFAMILY SSF46689 7 75 4.66E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c05870 f5ab5297508449cdd5d5d01066cbd8e6 289 Pfam PF01418 Helix-turn-helix domain, rpiR family 10 74 1.9E-11 T 12-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 MIM_c05870 f5ab5297508449cdd5d5d01066cbd8e6 289 Gene3D G3DSA:3.40.50.10490 96 276 2.9E-32 T 12-10-2018 MIM_c05870 f5ab5297508449cdd5d5d01066cbd8e6 289 Gene3D G3DSA:1.10.10.10 2 79 7.3E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c03580 970279e229d826188b7b9f2c73ec7b9b 464 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 437 444 - T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MIM_c03580 970279e229d826188b7b9f2c73ec7b9b 464 Gene3D G3DSA:1.10.10.1330 95 222 8.7E-20 T 12-10-2018 IPR038709 RNA polymerase sigma-54 factor, core-binding domain superfamily MIM_c03580 970279e229d826188b7b9f2c73ec7b9b 464 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 11 456 1.3E-129 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MIM_c03580 970279e229d826188b7b9f2c73ec7b9b 464 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 5 49 5.6E-14 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MIM_c03580 970279e229d826188b7b9f2c73ec7b9b 464 Pfam PF04552 Sigma-54, DNA binding domain 301 456 4.6E-57 T 12-10-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding MIM_c03580 970279e229d826188b7b9f2c73ec7b9b 464 PRINTS PR00045 Sigma-54 factor signature 432 450 5.0E-30 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MIM_c03580 970279e229d826188b7b9f2c73ec7b9b 464 PRINTS PR00045 Sigma-54 factor signature 374 385 5.0E-30 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MIM_c03580 970279e229d826188b7b9f2c73ec7b9b 464 PRINTS PR00045 Sigma-54 factor signature 358 370 5.0E-30 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MIM_c03580 970279e229d826188b7b9f2c73ec7b9b 464 PRINTS PR00045 Sigma-54 factor signature 165 182 5.0E-30 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MIM_c03580 970279e229d826188b7b9f2c73ec7b9b 464 Pfam PF04963 Sigma-54 factor, core binding domain 95 286 2.6E-54 T 12-10-2018 IPR007046 RNA polymerase sigma factor 54, core-binding domain GO:0003677|GO:0006352 MIM_c03580 970279e229d826188b7b9f2c73ec7b9b 464 PIRSF PIRSF000774 1 459 6.1E-140 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MIM_c03580 970279e229d826188b7b9f2c73ec7b9b 464 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 346 365 - T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MIM_c03580 970279e229d826188b7b9f2c73ec7b9b 464 Gene3D G3DSA:1.10.10.60 399 456 2.4E-21 T 12-10-2018 MIM_c12410 8efb4051be4c2c664e45a2d0ccbd1c95 298 Pfam PF00588 SpoU rRNA Methylase family 8 162 4.8E-32 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MIM_c12410 8efb4051be4c2c664e45a2d0ccbd1c95 298 SUPERFAMILY SSF75217 7 172 1.24E-28 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases MIM_c12410 8efb4051be4c2c664e45a2d0ccbd1c95 298 PIRSF PIRSF004808 4 190 1.2E-48 T 12-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 MIM_c12410 8efb4051be4c2c664e45a2d0ccbd1c95 298 PIRSF PIRSF004808 221 297 8.2E-8 T 12-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 MIM_c12410 8efb4051be4c2c664e45a2d0ccbd1c95 298 Gene3D G3DSA:3.40.1280.10 4 174 2.4E-54 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MIM_c12410 8efb4051be4c2c664e45a2d0ccbd1c95 298 Gene3D G3DSA:1.10.8.590 230 292 3.1E-21 T 12-10-2018 MIM_c08890 92490dbb2941b33ae2a6de0c31e10336 185 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 57 168 2.9E-9 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase MIM_c08890 92490dbb2941b33ae2a6de0c31e10336 185 Gene3D G3DSA:3.60.10.10 1 180 7.3E-55 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MIM_c08890 92490dbb2941b33ae2a6de0c31e10336 185 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 3 175 4.1E-50 T 12-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 MIM_c08890 92490dbb2941b33ae2a6de0c31e10336 185 SUPERFAMILY SSF56219 3 176 2.49E-51 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MIM_c07170 c38ebcb406652db2f9cf4c9e949ffdbb 325 Pfam PF01545 Cation efflux family 38 230 8.6E-42 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MIM_c07170 c38ebcb406652db2f9cf4c9e949ffdbb 325 Gene3D G3DSA:1.20.1510.10 32 230 1.9E-56 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily MIM_c07170 c38ebcb406652db2f9cf4c9e949ffdbb 325 SUPERFAMILY SSF160240 234 313 1.57E-19 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 MIM_c07170 c38ebcb406652db2f9cf4c9e949ffdbb 325 SUPERFAMILY SSF161111 31 232 5.89E-51 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily MIM_c07170 c38ebcb406652db2f9cf4c9e949ffdbb 325 Pfam PF16916 Dimerisation domain of Zinc Transporter 236 311 4.1E-20 T 12-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain MIM_c07170 c38ebcb406652db2f9cf4c9e949ffdbb 325 Gene3D G3DSA:3.30.70.1350 232 313 8.9E-19 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 MIM_c07170 c38ebcb406652db2f9cf4c9e949ffdbb 325 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 34 312 1.2E-61 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MIM_c29020 d1d191730cd3ddef32dfcff8e29a4e36 401 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 154 8.1E-21 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MIM_c29020 d1d191730cd3ddef32dfcff8e29a4e36 401 SUPERFAMILY SSF50129 318 369 1.55E-7 T 12-10-2018 IPR011032 GroES-like superfamily MIM_c29020 d1d191730cd3ddef32dfcff8e29a4e36 401 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 2 369 2.9E-188 T 12-10-2018 IPR014183 Alcohol dehydrogenase class III GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|MetaCyc: PWY-7798|Reactome: R-HSA-71384 MIM_c29020 d1d191730cd3ddef32dfcff8e29a4e36 401 Gene3D G3DSA:3.90.180.10 6 364 1.5E-137 T 12-10-2018 MIM_c29020 d1d191730cd3ddef32dfcff8e29a4e36 401 SUPERFAMILY SSF51735 160 333 1.09E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c29020 d1d191730cd3ddef32dfcff8e29a4e36 401 Pfam PF00107 Zinc-binding dehydrogenase 197 329 1.7E-25 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MIM_c29020 d1d191730cd3ddef32dfcff8e29a4e36 401 SUPERFAMILY SSF50129 1 193 7.0E-63 T 12-10-2018 IPR011032 GroES-like superfamily MIM_c29020 d1d191730cd3ddef32dfcff8e29a4e36 401 Gene3D G3DSA:3.40.50.720 174 312 1.5E-137 T 12-10-2018 MIM_c29020 d1d191730cd3ddef32dfcff8e29a4e36 401 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MIM_c29020 d1d191730cd3ddef32dfcff8e29a4e36 401 SMART SM00829 10 367 8.7E-4 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MIM_c30350 951f73d341327cc1efb302c063ff609d 425 PIRSF PIRSF001434 1 424 1.6E-133 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MIM_c30350 951f73d341327cc1efb302c063ff609d 425 Gene3D G3DSA:3.40.640.10 1 285 2.0E-101 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c30350 951f73d341327cc1efb302c063ff609d 425 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 196 210 - T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MIM_c30350 951f73d341327cc1efb302c063ff609d 425 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 421 3.9E-142 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MIM_c30350 951f73d341327cc1efb302c063ff609d 425 SUPERFAMILY SSF53383 1 420 1.58E-130 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c30350 951f73d341327cc1efb302c063ff609d 425 Gene3D G3DSA:3.90.1150.10 289 425 5.6E-54 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c30350 951f73d341327cc1efb302c063ff609d 425 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 2 421 9.2E-200 T 12-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 MIM_c21220 490034574945d30816425821904216a6 237 Gene3D G3DSA:3.20.20.70 1 237 4.3E-102 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c21220 490034574945d30816425821904216a6 237 SUPERFAMILY SSF63892 1 236 3.14E-96 T 12-10-2018 IPR036130 Pyridoxine 5'-phosphate synthase GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 MIM_c21220 490034574945d30816425821904216a6 237 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 4 234 1.1E-99 T 12-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 MIM_c21220 490034574945d30816425821904216a6 237 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 237 122.731 T 12-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 MIM_c21220 490034574945d30816425821904216a6 237 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 4 236 2.0E-90 T 12-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 MIM_c20610 9f9b5308d96b693e0dd30f4f2916448e 269 SUPERFAMILY SSF52096 13 263 4.06E-66 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c20610 9f9b5308d96b693e0dd30f4f2916448e 269 Gene3D G3DSA:1.10.12.10 208 266 2.6E-23 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MIM_c20610 9f9b5308d96b693e0dd30f4f2916448e 269 Gene3D G3DSA:3.90.226.10 1 207 1.8E-60 T 12-10-2018 MIM_c20610 9f9b5308d96b693e0dd30f4f2916448e 269 Pfam PF00378 Enoyl-CoA hydratase/isomerase 19 264 3.8E-45 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c35890 86ac7b2863e9f2c7ef1c709838f161ac 323 SUPERFAMILY SSF53850 112 285 5.43E-8 T 12-10-2018 MIM_c35890 86ac7b2863e9f2c7ef1c709838f161ac 323 Gene3D G3DSA:3.40.190.10 125 248 4.1E-113 T 12-10-2018 MIM_c35890 86ac7b2863e9f2c7ef1c709838f161ac 323 Gene3D G3DSA:3.40.190.150 28 313 4.1E-113 T 12-10-2018 MIM_c35890 86ac7b2863e9f2c7ef1c709838f161ac 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 319 3.6E-86 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c35890 86ac7b2863e9f2c7ef1c709838f161ac 323 PIRSF PIRSF017082 1 323 1.5E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c21620 ae21d3404f78d530030db760cb406749 530 Gene3D G3DSA:3.40.50.880 4 204 1.1E-52 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c21620 ae21d3404f78d530030db760cb406749 530 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 2 530 54.977 T 12-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 MIM_c21620 ae21d3404f78d530030db760cb406749 530 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 211 530 3.0E-147 T 12-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 MIM_c21620 ae21d3404f78d530030db760cb406749 530 PRINTS PR00096 Glutamine amidotransferase superfamily signature 175 188 3.5E-5 T 12-10-2018 MIM_c21620 ae21d3404f78d530030db760cb406749 530 PRINTS PR00096 Glutamine amidotransferase superfamily signature 79 90 3.5E-5 T 12-10-2018 MIM_c21620 ae21d3404f78d530030db760cb406749 530 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 5 202 1.3E-69 T 12-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 MIM_c21620 ae21d3404f78d530030db760cb406749 530 Gene3D G3DSA:3.30.300.10 404 530 2.4E-51 T 12-10-2018 MIM_c21620 ae21d3404f78d530030db760cb406749 530 SUPERFAMILY SSF52402 195 418 2.12E-60 T 12-10-2018 MIM_c21620 ae21d3404f78d530030db760cb406749 530 Pfam PF00958 GMP synthase C terminal domain 441 529 2.4E-42 T 12-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 MIM_c21620 ae21d3404f78d530030db760cb406749 530 PRINTS PR00097 Anthranilate synthase component II signature 79 90 3.4E-5 T 12-10-2018 MIM_c21620 ae21d3404f78d530030db760cb406749 530 PRINTS PR00097 Anthranilate synthase component II signature 175 188 3.4E-5 T 12-10-2018 MIM_c21620 ae21d3404f78d530030db760cb406749 530 SUPERFAMILY SSF52317 1 235 5.08E-56 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c21620 ae21d3404f78d530030db760cb406749 530 SUPERFAMILY SSF54810 403 530 1.11E-47 T 12-10-2018 MIM_c21620 ae21d3404f78d530030db760cb406749 530 Pfam PF02540 NAD synthase 221 293 2.6E-8 T 12-10-2018 IPR022310 NAD/GMP synthase MIM_c21620 ae21d3404f78d530030db760cb406749 530 Gene3D G3DSA:3.40.50.620 207 403 5.6E-76 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c21620 ae21d3404f78d530030db760cb406749 530 Pfam PF00117 Glutamine amidotransferase class-I 7 196 6.5E-34 T 12-10-2018 IPR017926 Glutamine amidotransferase MIM_c17050 c3c0e6b1e5c2d70e4fc50111b93d9302 312 Pfam PF00682 HMGL-like 6 275 1.0E-50 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 MIM_c17050 c3c0e6b1e5c2d70e4fc50111b93d9302 312 Gene3D G3DSA:3.20.20.70 2 287 7.9E-113 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c17050 c3c0e6b1e5c2d70e4fc50111b93d9302 312 SUPERFAMILY SSF51569 1 293 3.3E-75 T 12-10-2018 MIM_c35510 9e5d676e3bd8600dae4ca3a915ed5e8f 295 Gene3D G3DSA:1.10.10.10 1 89 1.5E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c35510 9e5d676e3bd8600dae4ca3a915ed5e8f 295 Gene3D G3DSA:3.40.190.290 91 288 3.5E-20 T 12-10-2018 MIM_c35510 9e5d676e3bd8600dae4ca3a915ed5e8f 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.1E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c35510 9e5d676e3bd8600dae4ca3a915ed5e8f 295 SUPERFAMILY SSF46785 2 110 2.56E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c35510 9e5d676e3bd8600dae4ca3a915ed5e8f 295 Pfam PF03466 LysR substrate binding domain 86 281 1.1E-22 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c35510 9e5d676e3bd8600dae4ca3a915ed5e8f 295 SUPERFAMILY SSF53850 88 288 1.93E-23 T 12-10-2018 MIM_c30690 a76388fd53ec5b646636aa8d0838910b 218 Gene3D G3DSA:1.10.10.10 2 75 1.9E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c30690 a76388fd53ec5b646636aa8d0838910b 218 SMART SM00895 84 205 3.7E-21 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c30690 a76388fd53ec5b646636aa8d0838910b 218 Gene3D G3DSA:1.20.120.530 78 215 2.2E-30 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c30690 a76388fd53ec5b646636aa8d0838910b 218 SUPERFAMILY SSF46785 13 83 2.37E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c30690 a76388fd53ec5b646636aa8d0838910b 218 SUPERFAMILY SSF48008 80 212 6.28E-25 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c30690 a76388fd53ec5b646636aa8d0838910b 218 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 7.0E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c30690 a76388fd53ec5b646636aa8d0838910b 218 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 7.0E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c30690 a76388fd53ec5b646636aa8d0838910b 218 SMART SM00345 16 74 9.9E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c30690 a76388fd53ec5b646636aa8d0838910b 218 Pfam PF07729 FCD domain 85 204 1.2E-23 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c30690 a76388fd53ec5b646636aa8d0838910b 218 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 2.5E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c00130 2febef0fe8bac527502e23440327aa62 1062 Gene3D G3DSA:1.20.1640.10 522 1030 0.0 T 12-10-2018 MIM_c00130 2febef0fe8bac527502e23440327aa62 1062 Gene3D G3DSA:3.30.70.1440 675 873 0.0 T 12-10-2018 MIM_c00130 2febef0fe8bac527502e23440327aa62 1062 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 3 1046 0.0 T 12-10-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0006855|GO:0015562|GO:0016021 MIM_c00130 2febef0fe8bac527502e23440327aa62 1062 Gene3D G3DSA:3.30.70.1430 576 674 0.0 T 12-10-2018 MIM_c00130 2febef0fe8bac527502e23440327aa62 1062 Gene3D G3DSA:3.30.70.1320 135 334 0.0 T 12-10-2018 MIM_c00130 2febef0fe8bac527502e23440327aa62 1062 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 2.4E-90 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c00130 2febef0fe8bac527502e23440327aa62 1062 PRINTS PR00702 Acriflavin resistance protein family signature 338 361 2.4E-90 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c00130 2febef0fe8bac527502e23440327aa62 1062 PRINTS PR00702 Acriflavin resistance protein family signature 365 386 2.4E-90 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c00130 2febef0fe8bac527502e23440327aa62 1062 PRINTS PR00702 Acriflavin resistance protein family signature 393 417 2.4E-90 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c00130 2febef0fe8bac527502e23440327aa62 1062 PRINTS PR00702 Acriflavin resistance protein family signature 630 644 2.4E-90 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c00130 2febef0fe8bac527502e23440327aa62 1062 PRINTS PR00702 Acriflavin resistance protein family signature 446 469 2.4E-90 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c00130 2febef0fe8bac527502e23440327aa62 1062 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 2.4E-90 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c00130 2febef0fe8bac527502e23440327aa62 1062 PRINTS PR00702 Acriflavin resistance protein family signature 561 578 2.4E-90 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c00130 2febef0fe8bac527502e23440327aa62 1062 PRINTS PR00702 Acriflavin resistance protein family signature 471 494 2.4E-90 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c00130 2febef0fe8bac527502e23440327aa62 1062 SUPERFAMILY SSF82714 185 273 1.83E-18 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c00130 2febef0fe8bac527502e23440327aa62 1062 SUPERFAMILY SSF82866 298 498 4.45E-50 T 12-10-2018 MIM_c00130 2febef0fe8bac527502e23440327aa62 1062 Gene3D G3DSA:3.30.70.1430 40 823 0.0 T 12-10-2018 MIM_c00130 2febef0fe8bac527502e23440327aa62 1062 SUPERFAMILY SSF82693 41 134 4.45E-25 T 12-10-2018 MIM_c00130 2febef0fe8bac527502e23440327aa62 1062 SUPERFAMILY SSF82866 811 1035 4.58E-44 T 12-10-2018 MIM_c00130 2febef0fe8bac527502e23440327aa62 1062 SUPERFAMILY SSF82693 574 677 1.05E-24 T 12-10-2018 MIM_c00130 2febef0fe8bac527502e23440327aa62 1062 SUPERFAMILY SSF82714 728 814 4.32E-20 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c00130 2febef0fe8bac527502e23440327aa62 1062 SUPERFAMILY SSF82693 138 332 7.06E-28 T 12-10-2018 MIM_c00130 2febef0fe8bac527502e23440327aa62 1062 Gene3D G3DSA:3.30.2090.10 181 277 0.0 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c00130 2febef0fe8bac527502e23440327aa62 1062 Gene3D G3DSA:1.20.1640.10 10 521 0.0 T 12-10-2018 MIM_c00130 2febef0fe8bac527502e23440327aa62 1062 Gene3D G3DSA:3.30.2090.10 727 815 0.0 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c00130 2febef0fe8bac527502e23440327aa62 1062 Pfam PF00873 AcrB/AcrD/AcrF family 3 1033 0.0 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c39640 2a357a9b73e8d2119fcb3040ffc68d1b 138 PRINTS PR00060 Ribosomal protein L16 signature 58 87 3.4E-41 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c39640 2a357a9b73e8d2119fcb3040ffc68d1b 138 PRINTS PR00060 Ribosomal protein L16 signature 88 117 3.4E-41 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c39640 2a357a9b73e8d2119fcb3040ffc68d1b 138 PRINTS PR00060 Ribosomal protein L16 signature 24 36 3.4E-41 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c39640 2a357a9b73e8d2119fcb3040ffc68d1b 138 PRINTS PR00060 Ribosomal protein L16 signature 42 53 3.4E-41 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c39640 2a357a9b73e8d2119fcb3040ffc68d1b 138 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 12-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c39640 2a357a9b73e8d2119fcb3040ffc68d1b 138 SUPERFAMILY SSF54686 1 134 7.2E-54 T 12-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 MIM_c39640 2a357a9b73e8d2119fcb3040ffc68d1b 138 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 4.3E-50 T 12-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 MIM_c39640 2a357a9b73e8d2119fcb3040ffc68d1b 138 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.688 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c39640 2a357a9b73e8d2119fcb3040ffc68d1b 138 Gene3D G3DSA:3.90.1170.10 1 137 3.7E-56 T 12-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 MIM_c39640 2a357a9b73e8d2119fcb3040ffc68d1b 138 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 7.1E-60 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c39640 2a357a9b73e8d2119fcb3040ffc68d1b 138 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 12-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c01900 98fd855ed7cb2391fd685ba5b4426ce4 406 SUPERFAMILY SSF46785 331 386 1.59E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c01900 98fd855ed7cb2391fd685ba5b4426ce4 406 Gene3D G3DSA:1.25.40.10 13 216 2.0E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MIM_c01900 98fd855ed7cb2391fd685ba5b4426ce4 406 Gene3D G3DSA:1.10.10.10 330 379 4.4E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c01900 98fd855ed7cb2391fd685ba5b4426ce4 406 Gene3D G3DSA:1.10.10.10 230 315 2.6E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c39600 389d755eae5b139104db8e942c3a0a0e 226 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 83 176 1.2E-13 T 12-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 MIM_c39600 389d755eae5b139104db8e942c3a0a0e 226 Gene3D G3DSA:2.60.120.620 1 178 6.9E-41 T 12-10-2018 MIM_c39600 389d755eae5b139104db8e942c3a0a0e 226 Gene3D G3DSA:4.10.860.20 180 226 4.0E-22 T 12-10-2018 MIM_c39600 389d755eae5b139104db8e942c3a0a0e 226 Hamap MF_00657 PKHD-type hydroxylase YbiX [ybiX]. 1 226 43.903 T 12-10-2018 IPR023550 PKHD-type hydroxylase GO:0016706|GO:0055114 MIM_c39600 389d755eae5b139104db8e942c3a0a0e 226 SMART SM00702 1 177 3.8E-21 T 12-10-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 MIM_c09600 2955a3b7a9a18efa2e917197fef8d443 258 Gene3D G3DSA:3.40.50.720 1 258 1.4E-72 T 12-10-2018 MIM_c09600 2955a3b7a9a18efa2e917197fef8d443 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 251 5.5E-49 T 12-10-2018 MIM_c09600 2955a3b7a9a18efa2e917197fef8d443 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.6E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c09600 2955a3b7a9a18efa2e917197fef8d443 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.6E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c09600 2955a3b7a9a18efa2e917197fef8d443 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.6E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c09600 2955a3b7a9a18efa2e917197fef8d443 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.1E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c09600 2955a3b7a9a18efa2e917197fef8d443 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.1E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c09600 2955a3b7a9a18efa2e917197fef8d443 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.1E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c09600 2955a3b7a9a18efa2e917197fef8d443 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.1E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c09600 2955a3b7a9a18efa2e917197fef8d443 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.1E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c09600 2955a3b7a9a18efa2e917197fef8d443 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.1E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c09600 2955a3b7a9a18efa2e917197fef8d443 258 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 179 0.0034 T 12-10-2018 MIM_c09600 2955a3b7a9a18efa2e917197fef8d443 258 SUPERFAMILY SSF51735 6 252 1.75E-66 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c16430 41cbbb1b824dadd0578799564eceb1b8 141 SUPERFAMILY SSF56214 11 137 7.19E-27 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MIM_c16430 41cbbb1b824dadd0578799564eceb1b8 141 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 12 138 22.829 T 12-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 MIM_c16430 41cbbb1b824dadd0578799564eceb1b8 141 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 11 138 3.1E-21 T 12-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 MIM_c16430 41cbbb1b824dadd0578799564eceb1b8 141 Gene3D G3DSA:3.90.470.20 8 139 2.3E-31 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MIM_c16430 41cbbb1b824dadd0578799564eceb1b8 141 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 10 138 3.6E-24 T 12-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 MIM_c16430 41cbbb1b824dadd0578799564eceb1b8 141 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 17 121 4.0E-34 T 12-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 MIM_c16430 41cbbb1b824dadd0578799564eceb1b8 141 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 13 115 2.9E-19 T 12-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MIM_c00390 487e4839f0f40891739bb158528d1952 425 PIRSF PIRSF016578 30 420 7.3E-36 T 12-10-2018 MIM_c00390 487e4839f0f40891739bb158528d1952 425 SUPERFAMILY SSF47203 260 422 7.09E-24 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c00390 487e4839f0f40891739bb158528d1952 425 Gene3D G3DSA:1.20.140.10 250 422 5.5E-55 T 12-10-2018 MIM_c00390 487e4839f0f40891739bb158528d1952 425 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 53 146 1.5E-10 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c00390 487e4839f0f40891739bb158528d1952 425 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 268 400 3.1E-20 T 12-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain MIM_c00390 487e4839f0f40891739bb158528d1952 425 TIGRFAM TIGR04022 sulfur_SfnB: sulfur acquisition oxidoreductase, SfnB family 33 424 6.2E-175 T 12-10-2018 IPR023922 Sulphate-starvation-induced SfnB MIM_c00390 487e4839f0f40891739bb158528d1952 425 SUPERFAMILY SSF56645 52 249 2.49E-44 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c00390 487e4839f0f40891739bb158528d1952 425 Gene3D G3DSA:1.10.540.10 40 148 2.9E-25 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c00390 487e4839f0f40891739bb158528d1952 425 Gene3D G3DSA:2.40.110.10 149 249 1.3E-28 T 12-10-2018 MIM_c34140 d920980f98bbbfd77e0c4c56de3a7419 556 Pfam PF00884 Sulfatase 9 381 1.0E-46 T 12-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 MIM_c34140 d920980f98bbbfd77e0c4c56de3a7419 556 Gene3D G3DSA:3.40.720.10 1 554 5.4E-76 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 MIM_c34140 d920980f98bbbfd77e0c4c56de3a7419 556 SUPERFAMILY SSF53649 40 545 1.18E-70 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 MIM_c03960 f18935b6fc3c4a8c78b693db37bb6730 320 SUPERFAMILY SSF51197 17 302 1.14E-76 T 12-10-2018 MIM_c03960 f18935b6fc3c4a8c78b693db37bb6730 320 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 26 295 5.0E-52 T 12-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 MIM_c03960 f18935b6fc3c4a8c78b693db37bb6730 320 Gene3D G3DSA:3.60.130.10 16 320 4.3E-84 T 12-10-2018 MIM_c00810 3c77a7c970f8da3698dceb439b6b1655 716 Gene3D G3DSA:3.40.30.60 376 505 9.1E-15 T 12-10-2018 MIM_c00810 3c77a7c970f8da3698dceb439b6b1655 716 Pfam PF00771 FHIPEP family 28 682 1.2E-205 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MIM_c00810 3c77a7c970f8da3698dceb439b6b1655 716 PIRSF PIRSF005419 1 697 1.6E-211 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MIM_c00810 3c77a7c970f8da3698dceb439b6b1655 716 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 71 90 1.6E-51 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MIM_c00810 3c77a7c970f8da3698dceb439b6b1655 716 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 152 170 1.6E-51 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MIM_c00810 3c77a7c970f8da3698dceb439b6b1655 716 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 133 149 1.6E-51 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MIM_c00810 3c77a7c970f8da3698dceb439b6b1655 716 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 233 247 1.6E-51 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MIM_c00810 3c77a7c970f8da3698dceb439b6b1655 716 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 34 47 1.6E-51 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MIM_c00810 3c77a7c970f8da3698dceb439b6b1655 716 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 182 199 1.6E-51 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MIM_c00810 3c77a7c970f8da3698dceb439b6b1655 716 TIGRFAM TIGR01399 hrcV: type III secretion protein, HrcV family 15 682 3.1E-220 T 12-10-2018 IPR006302 Type III secretion protein HrcV GO:0015031|GO:0016021 MIM_c00810 3c77a7c970f8da3698dceb439b6b1655 716 Gene3D G3DSA:1.10.490.80 596 690 7.0E-11 T 12-10-2018 MIM_c00810 3c77a7c970f8da3698dceb439b6b1655 716 Gene3D G3DSA:1.10.8.540 506 594 4.8E-26 T 12-10-2018 MIM_c07050 bbb1de3331d0fd58d19915070d155de7 443 SUPERFAMILY SSF53822 31 403 6.06E-43 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c07050 bbb1de3331d0fd58d19915070d155de7 443 Pfam PF13458 Periplasmic binding protein 31 399 2.2E-76 T 12-10-2018 IPR028081 Leucine-binding protein domain MIM_c07050 bbb1de3331d0fd58d19915070d155de7 443 Gene3D G3DSA:3.40.50.2300 151 293 1.8E-69 T 12-10-2018 MIM_c07050 bbb1de3331d0fd58d19915070d155de7 443 Gene3D G3DSA:3.40.50.2300 40 362 1.8E-69 T 12-10-2018 MIM_c09690 6e1e8b10f6d540863f86438f8f3d2488 359 Gene3D G3DSA:1.10.150.170 131 233 3.2E-94 T 12-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 MIM_c09690 6e1e8b10f6d540863f86438f8f3d2488 359 Gene3D G3DSA:3.40.50.150 38 326 3.2E-94 T 12-10-2018 MIM_c09690 6e1e8b10f6d540863f86438f8f3d2488 359 Pfam PF01795 MraW methylase family 6 326 8.6E-102 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 MIM_c09690 6e1e8b10f6d540863f86438f8f3d2488 359 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 37 326 1.4E-100 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 MIM_c09690 6e1e8b10f6d540863f86438f8f3d2488 359 SUPERFAMILY SSF81799 133 232 2.09E-33 T 12-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 MIM_c09690 6e1e8b10f6d540863f86438f8f3d2488 359 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 8 327 35.224 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 MIM_c09690 6e1e8b10f6d540863f86438f8f3d2488 359 PIRSF PIRSF004486 3 328 9.5E-95 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 MIM_c09690 6e1e8b10f6d540863f86438f8f3d2488 359 SUPERFAMILY SSF53335 8 326 6.95E-35 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c23590 be4b499ae0b33139af0f96b8cf58202f 162 Pfam PF13279 Thioesterase-like superfamily 32 148 1.1E-13 T 12-10-2018 MIM_c23590 be4b499ae0b33139af0f96b8cf58202f 162 Gene3D G3DSA:3.10.129.10 14 152 1.4E-29 T 12-10-2018 MIM_c23590 be4b499ae0b33139af0f96b8cf58202f 162 SUPERFAMILY SSF54637 24 151 9.2E-27 T 12-10-2018 IPR029069 HotDog domain superfamily MIM_c36100 a52a47e76d7b561b3b1dc82349d906c8 248 SUPERFAMILY SSF52096 3 247 1.38E-65 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c36100 a52a47e76d7b561b3b1dc82349d906c8 248 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 248 3.4E-46 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c36100 a52a47e76d7b561b3b1dc82349d906c8 248 Gene3D G3DSA:3.90.226.10 1 190 4.1E-51 T 12-10-2018 MIM_c36100 a52a47e76d7b561b3b1dc82349d906c8 248 Gene3D G3DSA:1.10.12.10 191 248 4.8E-10 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MIM_c29980 fd1316cbd00640ed014fff67ba6b4690 426 Gene3D G3DSA:2.120.10.30 171 426 2.0E-71 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MIM_c29980 fd1316cbd00640ed014fff67ba6b4690 426 SUPERFAMILY SSF69304 163 423 2.75E-50 T 12-10-2018 MIM_c29980 fd1316cbd00640ed014fff67ba6b4690 426 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 34 422 1.1E-113 T 12-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 MIM_c29980 fd1316cbd00640ed014fff67ba6b4690 426 Pfam PF07676 WD40-like Beta Propeller Repeat 200 226 3.1E-7 T 12-10-2018 IPR011659 WD40-like Beta Propeller MIM_c29980 fd1316cbd00640ed014fff67ba6b4690 426 Pfam PF07676 WD40-like Beta Propeller Repeat 240 270 1.5E-4 T 12-10-2018 IPR011659 WD40-like Beta Propeller MIM_c29980 fd1316cbd00640ed014fff67ba6b4690 426 Pfam PF07676 WD40-like Beta Propeller Repeat 326 358 0.0019 T 12-10-2018 IPR011659 WD40-like Beta Propeller MIM_c29980 fd1316cbd00640ed014fff67ba6b4690 426 Pfam PF07676 WD40-like Beta Propeller Repeat 281 316 2.7E-9 T 12-10-2018 IPR011659 WD40-like Beta Propeller MIM_c29980 fd1316cbd00640ed014fff67ba6b4690 426 SUPERFAMILY SSF52964 51 167 1.44E-19 T 12-10-2018 MIM_c29980 fd1316cbd00640ed014fff67ba6b4690 426 Pfam PF04052 TolB amino-terminal domain 49 137 7.4E-10 T 12-10-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 MIM_c29980 fd1316cbd00640ed014fff67ba6b4690 426 Hamap MF_00671 Tol-Pal system protein TolB [tolB]. 24 421 38.056 T 12-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 MIM_c29980 fd1316cbd00640ed014fff67ba6b4690 426 Gene3D G3DSA:3.40.50.10070 39 170 1.2E-21 T 12-10-2018 IPR036752 TolB, N-terminal domain superfamily GO:0015031|GO:0042597 MIM_c34650 dabc3bbb03020cc850b2efc976531d7b 254 SMART SM00382 26 207 1.9E-19 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c34650 dabc3bbb03020cc850b2efc976531d7b 254 SUPERFAMILY SSF52540 1 226 2.05E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c34650 dabc3bbb03020cc850b2efc976531d7b 254 Pfam PF00005 ABC transporter 17 157 3.8E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c34650 dabc3bbb03020cc850b2efc976531d7b 254 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c34650 dabc3bbb03020cc850b2efc976531d7b 254 Gene3D G3DSA:3.40.50.300 1 221 5.4E-70 T 12-10-2018 MIM_c21200 00a14bd4833a525463b5c0232d12c4bd 195 Pfam PF03334 Na+/H+ antiporter subunit 16 95 2.7E-13 T 12-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 MIM_c20590 674c9e48d98dcc4df41921812d83e84d 136 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 18 54 7.7E-11 T 12-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal MIM_c20590 674c9e48d98dcc4df41921812d83e84d 136 SUPERFAMILY SSF50249 6 126 3.43E-38 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c20590 674c9e48d98dcc4df41921812d83e84d 136 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 55 120 2.3E-22 T 12-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal MIM_c20590 674c9e48d98dcc4df41921812d83e84d 136 Gene3D G3DSA:1.10.12.20 8 57 2.2E-7 T 12-10-2018 MIM_c01500 a120d22975da37ee70872130abfd3e29 193 Gene3D G3DSA:3.40.50.360 3 175 9.2E-43 T 12-10-2018 IPR029039 Flavoprotein-like superfamily MIM_c01500 a120d22975da37ee70872130abfd3e29 193 Pfam PF03358 NADPH-dependent FMN reductase 7 148 1.9E-32 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 MIM_c01500 a120d22975da37ee70872130abfd3e29 193 SUPERFAMILY SSF52218 7 166 2.02E-30 T 12-10-2018 IPR029039 Flavoprotein-like superfamily MIM_c01500 a120d22975da37ee70872130abfd3e29 193 TIGRFAM TIGR03566 FMN_reduc_MsuE: FMN reductase 7 177 2.7E-67 T 12-10-2018 IPR019912 FMN reductase, MsuE-like MIM_c25590 29589de22068b3867acab8a9f27ece2a 312 SUPERFAMILY SSF56281 38 276 1.76E-47 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MIM_c25590 29589de22068b3867acab8a9f27ece2a 312 Pfam PF00753 Metallo-beta-lactamase superfamily 39 229 1.6E-24 T 12-10-2018 IPR001279 Metallo-beta-lactamase MIM_c25590 29589de22068b3867acab8a9f27ece2a 312 Gene3D G3DSA:3.60.15.10 25 312 1.6E-106 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MIM_c25590 29589de22068b3867acab8a9f27ece2a 312 SMART SM00849 39 229 4.8E-24 T 12-10-2018 IPR001279 Metallo-beta-lactamase MIM_c12160 d5481ddfb652a7c8ff12d05764648f06 320 Gene3D G3DSA:1.20.120.1760 5 154 3.5E-16 T 12-10-2018 MIM_c12160 d5481ddfb652a7c8ff12d05764648f06 320 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 56 78 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MIM_c12160 d5481ddfb652a7c8ff12d05764648f06 320 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 20 183 8.3E-34 T 12-10-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 MIM_c12160 d5481ddfb652a7c8ff12d05764648f06 320 Pfam PF01066 CDP-alcohol phosphatidyltransferase 15 78 8.9E-14 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MIM_c31440 6dc7e3815537669915a22234e67d366a 275 Pfam PF01925 Sulfite exporter TauE/SafE 12 265 2.6E-51 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MIM_c11220 1c3a6993f820d340267754cd10c06c5f 282 Pfam PF13847 Methyltransferase domain 72 208 9.2E-10 T 12-10-2018 IPR025714 Methyltransferase domain MIM_c11220 1c3a6993f820d340267754cd10c06c5f 282 SUPERFAMILY SSF53335 54 168 6.46E-26 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c11220 1c3a6993f820d340267754cd10c06c5f 282 Gene3D G3DSA:3.40.50.150 50 207 1.8E-42 T 12-10-2018 MIM_c19020 7b854b580363db7fd152cad96472154f 315 SUPERFAMILY SSF46785 2 86 1.43E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c19020 7b854b580363db7fd152cad96472154f 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.4E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c19020 7b854b580363db7fd152cad96472154f 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.4E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c19020 7b854b580363db7fd152cad96472154f 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.4E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c19020 7b854b580363db7fd152cad96472154f 315 SUPERFAMILY SSF53850 88 299 9.95E-40 T 12-10-2018 MIM_c19020 7b854b580363db7fd152cad96472154f 315 Pfam PF03466 LysR substrate binding domain 88 297 5.0E-48 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c19020 7b854b580363db7fd152cad96472154f 315 Gene3D G3DSA:3.40.190.10 92 295 8.7E-75 T 12-10-2018 MIM_c19020 7b854b580363db7fd152cad96472154f 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 2.3E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c19020 7b854b580363db7fd152cad96472154f 315 Gene3D G3DSA:3.40.190.10 161 272 8.7E-75 T 12-10-2018 MIM_c19020 7b854b580363db7fd152cad96472154f 315 Gene3D G3DSA:1.10.10.10 1 85 3.8E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c04470 e165ddf12f1550aa96331a3d93c2d801 355 Gene3D G3DSA:3.40.50.2000 14 343 3.5E-51 T 12-10-2018 MIM_c04470 e165ddf12f1550aa96331a3d93c2d801 355 SUPERFAMILY SSF53756 2 350 1.26E-61 T 12-10-2018 MIM_c04470 e165ddf12f1550aa96331a3d93c2d801 355 Pfam PF13439 Glycosyltransferase Family 4 13 146 5.6E-13 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MIM_c04470 e165ddf12f1550aa96331a3d93c2d801 355 Pfam PF00534 Glycosyl transferases group 1 172 321 2.5E-26 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 MIM_c04470 e165ddf12f1550aa96331a3d93c2d801 355 Gene3D G3DSA:3.40.50.2000 158 334 3.5E-51 T 12-10-2018 MIM_c35320 761ff77d85c7be1c697cb184a469fbff 395 Gene3D G3DSA:1.20.1250.20 197 382 2.3E-16 T 12-10-2018 MIM_c35320 761ff77d85c7be1c697cb184a469fbff 395 SUPERFAMILY SSF103473 3 375 1.44E-46 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c35320 761ff77d85c7be1c697cb184a469fbff 395 Pfam PF07690 Major Facilitator Superfamily 8 317 1.2E-34 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c35320 761ff77d85c7be1c697cb184a469fbff 395 Gene3D G3DSA:1.20.1250.20 2 196 4.6E-22 T 12-10-2018 MIM_c11760 0ade9f2a2f970b67bc56436cdbdd592f 364 TIGRFAM TIGR02484 CitB: CitB domain protein 9 360 1.3E-112 T 12-10-2018 IPR012830 Citrate utilization protein B MIM_c11760 0ade9f2a2f970b67bc56436cdbdd592f 364 SUPERFAMILY SSF103501 153 355 1.01E-24 T 12-10-2018 IPR036197 NarG-like superfamily MIM_c17750 4a0df7ea3f67047f5b87e97063c36664 181 SMART SM00347 31 132 1.1E-22 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c17750 4a0df7ea3f67047f5b87e97063c36664 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 122 142 9.9E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c17750 4a0df7ea3f67047f5b87e97063c36664 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 73 88 9.9E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c17750 4a0df7ea3f67047f5b87e97063c36664 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 56 72 9.9E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c17750 4a0df7ea3f67047f5b87e97063c36664 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 92 108 9.9E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c17750 4a0df7ea3f67047f5b87e97063c36664 181 SUPERFAMILY SSF46785 11 148 1.73E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c17750 4a0df7ea3f67047f5b87e97063c36664 181 Pfam PF01047 MarR family 40 97 3.3E-16 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c17750 4a0df7ea3f67047f5b87e97063c36664 181 ProSitePatterns PS01117 MarR-type HTH domain signature. 71 105 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MIM_c17750 4a0df7ea3f67047f5b87e97063c36664 181 Gene3D G3DSA:1.10.10.10 6 143 1.2E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c33240 28775e067935f0f66bbc40aa04e655f1 1012 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 370 380 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site MIM_c33240 28775e067935f0f66bbc40aa04e655f1 1012 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 111 121 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site MIM_c33240 28775e067935f0f66bbc40aa04e655f1 1012 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 533 1008 1.1E-59 T 12-10-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 MIM_c33240 28775e067935f0f66bbc40aa04e655f1 1012 Gene3D G3DSA:2.40.128.130 716 1012 4.3E-77 T 12-10-2018 IPR036709 Autotransporter beta-domain superfamily MIM_c33240 28775e067935f0f66bbc40aa04e655f1 1012 SUPERFAMILY SSF51126 335 603 6.91E-17 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor MIM_c33240 28775e067935f0f66bbc40aa04e655f1 1012 Pfam PF03797 Autotransporter beta-domain 743 992 8.6E-66 T 12-10-2018 IPR005546 Autotransporter beta-domain MIM_c33240 28775e067935f0f66bbc40aa04e655f1 1012 SUPERFAMILY SSF103515 683 1012 2.88E-68 T 12-10-2018 IPR036709 Autotransporter beta-domain superfamily MIM_c33240 28775e067935f0f66bbc40aa04e655f1 1012 SUPERFAMILY SSF52743 39 429 1.44E-65 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 MIM_c33240 28775e067935f0f66bbc40aa04e655f1 1012 Pfam PF12951 Passenger-associated-transport-repeat 458 485 4.4E-7 T 12-10-2018 IPR013425 Autotransporter-associated beta strand repeat MIM_c33240 28775e067935f0f66bbc40aa04e655f1 1012 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 63 74 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site MIM_c33240 28775e067935f0f66bbc40aa04e655f1 1012 Pfam PF00082 Subtilase family 58 417 6.8E-47 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MIM_c33240 28775e067935f0f66bbc40aa04e655f1 1012 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 458 485 7.7E-10 T 12-10-2018 IPR013425 Autotransporter-associated beta strand repeat MIM_c33240 28775e067935f0f66bbc40aa04e655f1 1012 PRINTS PR00723 Subtilisin serine protease family (S8) signature 58 77 1.2E-19 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related MIM_c33240 28775e067935f0f66bbc40aa04e655f1 1012 PRINTS PR00723 Subtilisin serine protease family (S8) signature 369 385 1.2E-19 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related MIM_c33240 28775e067935f0f66bbc40aa04e655f1 1012 PRINTS PR00723 Subtilisin serine protease family (S8) signature 107 120 1.2E-19 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related MIM_c33240 28775e067935f0f66bbc40aa04e655f1 1012 SMART SM00869 740 1002 7.0E-56 T 12-10-2018 IPR005546 Autotransporter beta-domain MIM_c05420 bda67c487338f82fc2753e1df15f2e41 389 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 5 388 4.6E-99 T 12-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 MIM_c05420 bda67c487338f82fc2753e1df15f2e41 389 Gene3D G3DSA:3.30.9.50 79 269 5.7E-80 T 12-10-2018 MIM_c05420 bda67c487338f82fc2753e1df15f2e41 389 SUPERFAMILY SSF51905 1 388 7.12E-48 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c05420 bda67c487338f82fc2753e1df15f2e41 389 Pfam PF01494 FAD binding domain 3 338 2.2E-18 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 MIM_c05420 bda67c487338f82fc2753e1df15f2e41 389 Gene3D G3DSA:3.50.50.60 5 336 5.7E-80 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c05420 bda67c487338f82fc2753e1df15f2e41 389 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 293 306 - T 12-10-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 MIM_c05420 bda67c487338f82fc2753e1df15f2e41 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 5.3E-20 T 12-10-2018 MIM_c05420 bda67c487338f82fc2753e1df15f2e41 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 5.3E-20 T 12-10-2018 MIM_c05420 bda67c487338f82fc2753e1df15f2e41 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 5.3E-20 T 12-10-2018 MIM_c05420 bda67c487338f82fc2753e1df15f2e41 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 5.3E-20 T 12-10-2018 MIM_c27000 69ae43c8d735561d31e098a73729a51c 203 Pfam PF04955 HupE / UreJ protein 18 199 1.7E-57 T 12-10-2018 IPR007038 Hydrogenase/Urease accessory protein HupE/UreJ protein MIM_c27000 69ae43c8d735561d31e098a73729a51c 203 PIRSF PIRSF016919 8 203 3.0E-50 T 12-10-2018 IPR007038 Hydrogenase/Urease accessory protein HupE/UreJ protein MIM_c31070 da4278687ca41db2e64c0d43531ac918 207 Pfam PF00857 Isochorismatase family 24 199 4.6E-42 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 MIM_c31070 da4278687ca41db2e64c0d43531ac918 207 Gene3D G3DSA:3.40.50.850 3 205 1.4E-59 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MIM_c31070 da4278687ca41db2e64c0d43531ac918 207 SUPERFAMILY SSF52499 23 204 1.02E-52 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MIM_c14310 ddbe21dea0b60438d4a8436c73b6f3b0 370 Gene3D G3DSA:3.40.50.720 174 312 1.6E-145 T 12-10-2018 MIM_c14310 ddbe21dea0b60438d4a8436c73b6f3b0 370 SUPERFAMILY SSF50129 1 185 3.8E-69 T 12-10-2018 IPR011032 GroES-like superfamily MIM_c14310 ddbe21dea0b60438d4a8436c73b6f3b0 370 Pfam PF00107 Zinc-binding dehydrogenase 197 320 1.5E-22 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MIM_c14310 ddbe21dea0b60438d4a8436c73b6f3b0 370 SUPERFAMILY SSF50129 319 369 2.12E-12 T 12-10-2018 IPR011032 GroES-like superfamily MIM_c14310 ddbe21dea0b60438d4a8436c73b6f3b0 370 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 154 9.8E-24 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MIM_c14310 ddbe21dea0b60438d4a8436c73b6f3b0 370 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 3 369 2.5E-188 T 12-10-2018 IPR014183 Alcohol dehydrogenase class III GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|MetaCyc: PWY-7798|Reactome: R-HSA-71384 MIM_c14310 ddbe21dea0b60438d4a8436c73b6f3b0 370 SUPERFAMILY SSF51735 160 334 5.55E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c14310 ddbe21dea0b60438d4a8436c73b6f3b0 370 Gene3D G3DSA:3.90.180.10 6 364 1.6E-145 T 12-10-2018 MIM_c14310 ddbe21dea0b60438d4a8436c73b6f3b0 370 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MIM_c14310 ddbe21dea0b60438d4a8436c73b6f3b0 370 SMART SM00829 12 367 2.2E-4 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MIM_c22420 4607d7fa9b0bb12edf6186ac58c485de 639 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 232 635 7.3E-81 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 MIM_c22420 4607d7fa9b0bb12edf6186ac58c485de 639 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 57 182 3.3E-27 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ MIM_c22420 4607d7fa9b0bb12edf6186ac58c485de 639 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 224 634 6.6E-86 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit MIM_c30240 c9fa2268782698e47d07be9ec92274ed 113 SUPERFAMILY SSF103481 9 108 6.54E-21 T 12-10-2018 MIM_c30240 c9fa2268782698e47d07be9ec92274ed 113 Pfam PF00893 Small Multidrug Resistance protein 6 97 6.3E-29 T 12-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 MIM_c30240 c9fa2268782698e47d07be9ec92274ed 113 Gene3D G3DSA:1.10.3730.20 4 113 8.6E-38 T 12-10-2018 MIM_c01510 cf1f62ffc5a7c5f1bf36510d195b5572 310 Gene3D G3DSA:1.10.8.450 238 270 1.2E-102 T 12-10-2018 MIM_c01510 cf1f62ffc5a7c5f1bf36510d195b5572 310 Pfam PF09084 NMT1/THI5 like 52 227 8.0E-14 T 12-10-2018 IPR015168 SsuA/THI5-like MIM_c01510 cf1f62ffc5a7c5f1bf36510d195b5572 310 Gene3D G3DSA:3.40.190.10 29 300 1.2E-102 T 12-10-2018 MIM_c01510 cf1f62ffc5a7c5f1bf36510d195b5572 310 SUPERFAMILY SSF53850 26 257 7.35E-51 T 12-10-2018 MIM_c01510 cf1f62ffc5a7c5f1bf36510d195b5572 310 SMART SM00062 27 247 5.9E-20 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c01510 cf1f62ffc5a7c5f1bf36510d195b5572 310 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 29 309 2.1E-72 T 12-10-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 MIM_c01510 cf1f62ffc5a7c5f1bf36510d195b5572 310 Gene3D G3DSA:3.40.190.10 107 206 1.2E-102 T 12-10-2018 MIM_c23700 d117468f48df99a294a6cba15e0fbdcc 558 Pfam PF13193 AMP-binding enzyme C-terminal domain 471 545 1.3E-17 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MIM_c23700 d117468f48df99a294a6cba15e0fbdcc 558 Pfam PF00501 AMP-binding enzyme 29 462 1.2E-106 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MIM_c23700 d117468f48df99a294a6cba15e0fbdcc 558 Gene3D G3DSA:3.40.50.12780 11 453 1.5E-116 T 12-10-2018 MIM_c23700 d117468f48df99a294a6cba15e0fbdcc 558 ProSitePatterns PS00455 Putative AMP-binding domain signature. 211 222 - T 12-10-2018 IPR020845 AMP-binding, conserved site MIM_c23700 d117468f48df99a294a6cba15e0fbdcc 558 SUPERFAMILY SSF56801 23 553 4.84E-148 T 12-10-2018 MIM_c23700 d117468f48df99a294a6cba15e0fbdcc 558 Gene3D G3DSA:3.30.300.310 458 557 9.4E-30 T 12-10-2018 MIM_c17520 6775a86b92049ddf42db7de55ebde429 146 SUPERFAMILY SSF55331 2 132 1.37E-19 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily MIM_c17520 6775a86b92049ddf42db7de55ebde429 146 Pfam PF02962 5-carboxymethyl-2-hydroxymuconate isomerase 2 119 1.3E-10 T 12-10-2018 IPR004220 5-carboxymethyl-2-hydroxymuconate isomerase GO:0008704|GO:0019439 KEGG: 00350+5.3.3.10 MIM_c17520 6775a86b92049ddf42db7de55ebde429 146 Gene3D G3DSA:3.30.429.10 1 146 3.0E-47 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily MIM_c10010 7c9ab2cc4f580247a79ad31e3b609882 336 SUPERFAMILY SSF81345 11 332 3.4E-81 T 12-10-2018 IPR037294 ABC transporter, BtuC-like MIM_c10010 7c9ab2cc4f580247a79ad31e3b609882 336 Gene3D G3DSA:1.10.3470.10 11 336 6.4E-102 T 12-10-2018 IPR037294 ABC transporter, BtuC-like MIM_c10010 7c9ab2cc4f580247a79ad31e3b609882 336 Pfam PF01032 FecCD transport family 23 332 2.8E-87 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MIM_c16580 09064a12f6ecb56b2731dc1201215ce0 757 SUPERFAMILY SSF51998 222 740 4.88E-165 T 12-10-2018 MIM_c16580 09064a12f6ecb56b2731dc1201215ce0 757 Gene3D G3DSA:3.20.70.20 78 742 2.6E-155 T 12-10-2018 MIM_c16580 09064a12f6ecb56b2731dc1201215ce0 757 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 599 621 - T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MIM_c16580 09064a12f6ecb56b2731dc1201215ce0 757 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 142 219 5.1E-12 T 12-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MIM_c16580 09064a12f6ecb56b2731dc1201215ce0 757 PRINTS PR01183 Ribonucleotide reductase large chain signature 298 317 2.5E-36 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MIM_c16580 09064a12f6ecb56b2731dc1201215ce0 757 PRINTS PR01183 Ribonucleotide reductase large chain signature 610 637 2.5E-36 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MIM_c16580 09064a12f6ecb56b2731dc1201215ce0 757 PRINTS PR01183 Ribonucleotide reductase large chain signature 539 562 2.5E-36 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MIM_c16580 09064a12f6ecb56b2731dc1201215ce0 757 PRINTS PR01183 Ribonucleotide reductase large chain signature 511 533 2.5E-36 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MIM_c16580 09064a12f6ecb56b2731dc1201215ce0 757 PRINTS PR01183 Ribonucleotide reductase large chain signature 473 496 2.5E-36 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MIM_c16580 09064a12f6ecb56b2731dc1201215ce0 757 PRINTS PR01183 Ribonucleotide reductase large chain signature 433 444 2.5E-36 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MIM_c16580 09064a12f6ecb56b2731dc1201215ce0 757 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 145 735 7.8E-176 T 12-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MIM_c16580 09064a12f6ecb56b2731dc1201215ce0 757 SUPERFAMILY SSF48168 10 221 1.83E-76 T 12-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MIM_c16580 09064a12f6ecb56b2731dc1201215ce0 757 Pfam PF03477 ATP cone domain 6 92 9.5E-18 T 12-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 MIM_c16580 09064a12f6ecb56b2731dc1201215ce0 757 Pfam PF02867 Ribonucleotide reductase, barrel domain 223 663 3.9E-112 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MIM_c36700 7707d705518189c30aa957bb8523666c 311 SMART SM00849 55 240 1.3E-18 T 12-10-2018 IPR001279 Metallo-beta-lactamase MIM_c36700 7707d705518189c30aa957bb8523666c 311 Pfam PF00753 Metallo-beta-lactamase superfamily 53 240 4.8E-24 T 12-10-2018 IPR001279 Metallo-beta-lactamase MIM_c36700 7707d705518189c30aa957bb8523666c 311 SUPERFAMILY SSF56281 12 292 1.34E-56 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MIM_c36700 7707d705518189c30aa957bb8523666c 311 TIGRFAM TIGR04559 SoxH_rel_PQQ_2: quinoprotein relay system zinc metallohydrolase 2 27 311 3.2E-110 T 12-10-2018 IPR030829 Quinoprotein relay system zinc metallohydrolase 2 MIM_c36700 7707d705518189c30aa957bb8523666c 311 Gene3D G3DSA:3.60.15.10 20 267 3.1E-45 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MIM_c34130 a74391243be2c52ed1bff03d9cc844d0 217 Gene3D G3DSA:3.40.50.850 9 202 2.6E-46 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MIM_c34130 a74391243be2c52ed1bff03d9cc844d0 217 SUPERFAMILY SSF52499 7 204 3.66E-47 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MIM_c34130 a74391243be2c52ed1bff03d9cc844d0 217 Pfam PF00857 Isochorismatase family 16 166 1.8E-23 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 MIM_c32060 00e6efccc021dadea04292ea2fdce803 131 Pfam PF01219 Prokaryotic diacylglycerol kinase 24 122 1.8E-29 T 12-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 MIM_c32060 00e6efccc021dadea04292ea2fdce803 131 Gene3D G3DSA:1.10.3830.10 9 128 2.6E-32 T 12-10-2018 IPR036945 Diacylglycerol kinase (DAGK) superfamily GO:0008610|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 MIM_c04850 776383735bf86d08176be48d9e9e5643 440 Gene3D G3DSA:3.40.50.1980 238 354 1.4E-126 T 12-10-2018 MIM_c04850 776383735bf86d08176be48d9e9e5643 440 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 3 432 41.237 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MIM_c04850 776383735bf86d08176be48d9e9e5643 440 PRINTS PR00083 Histidinol dehydrogenase signature 37 61 7.3E-84 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MIM_c04850 776383735bf86d08176be48d9e9e5643 440 PRINTS PR00083 Histidinol dehydrogenase signature 175 201 7.3E-84 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MIM_c04850 776383735bf86d08176be48d9e9e5643 440 PRINTS PR00083 Histidinol dehydrogenase signature 366 384 7.3E-84 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MIM_c04850 776383735bf86d08176be48d9e9e5643 440 PRINTS PR00083 Histidinol dehydrogenase signature 234 255 7.3E-84 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MIM_c04850 776383735bf86d08176be48d9e9e5643 440 PRINTS PR00083 Histidinol dehydrogenase signature 325 350 7.3E-84 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MIM_c04850 776383735bf86d08176be48d9e9e5643 440 PRINTS PR00083 Histidinol dehydrogenase signature 256 275 7.3E-84 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MIM_c04850 776383735bf86d08176be48d9e9e5643 440 PRINTS PR00083 Histidinol dehydrogenase signature 205 230 7.3E-84 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MIM_c04850 776383735bf86d08176be48d9e9e5643 440 PRINTS PR00083 Histidinol dehydrogenase signature 141 167 7.3E-84 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MIM_c04850 776383735bf86d08176be48d9e9e5643 440 Gene3D G3DSA:3.40.50.1980 34 236 1.4E-126 T 12-10-2018 MIM_c04850 776383735bf86d08176be48d9e9e5643 440 Pfam PF00815 Histidinol dehydrogenase 29 432 2.6E-167 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MIM_c04850 776383735bf86d08176be48d9e9e5643 440 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 37 431 5.2E-160 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MIM_c04850 776383735bf86d08176be48d9e9e5643 440 PIRSF PIRSF000099 7 435 1.2E-160 T 12-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MIM_c04850 776383735bf86d08176be48d9e9e5643 440 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 234 266 - T 12-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 MIM_c04850 776383735bf86d08176be48d9e9e5643 440 SUPERFAMILY SSF53720 30 434 1.67E-87 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c12010 86c4dd712bc66afd431610bdef2c047e 273 Gene3D G3DSA:3.30.450.40 99 268 1.1E-30 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c12010 86c4dd712bc66afd431610bdef2c047e 273 Gene3D G3DSA:1.10.10.10 14 93 6.3E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c12010 86c4dd712bc66afd431610bdef2c047e 273 SUPERFAMILY SSF55781 92 268 6.54E-33 T 12-10-2018 MIM_c12010 86c4dd712bc66afd431610bdef2c047e 273 Pfam PF09339 IclR helix-turn-helix domain 27 77 3.5E-15 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c12010 86c4dd712bc66afd431610bdef2c047e 273 SUPERFAMILY SSF46785 25 97 2.84E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c12010 86c4dd712bc66afd431610bdef2c047e 273 Pfam PF01614 Bacterial transcriptional regulator 144 265 1.2E-9 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal MIM_c12010 86c4dd712bc66afd431610bdef2c047e 273 SMART SM00346 25 115 1.7E-21 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c33470 d5b2531f87f430b5d4427c621c82752a 103 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 37 87 3.3E-7 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MIM_c33470 d5b2531f87f430b5d4427c621c82752a 103 SUPERFAMILY SSF54292 17 95 2.62E-17 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MIM_c33470 d5b2531f87f430b5d4427c621c82752a 103 Gene3D G3DSA:3.10.20.30 1 101 8.2E-15 T 12-10-2018 IPR012675 Beta-grasp domain superfamily MIM_c33470 d5b2531f87f430b5d4427c621c82752a 103 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 41 49 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MIM_c24940 c245a643fc6315acdab964317e24d4e9 262 Gene3D G3DSA:3.90.226.10 3 203 5.4E-48 T 12-10-2018 MIM_c24940 c245a643fc6315acdab964317e24d4e9 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 261 9.1E-39 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c24940 c245a643fc6315acdab964317e24d4e9 262 SUPERFAMILY SSF52096 6 262 3.09E-59 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c24940 c245a643fc6315acdab964317e24d4e9 262 Gene3D G3DSA:1.10.12.10 205 262 2.0E-13 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MIM_c13510 85f6db374b6926e23040be4bcb2edf6c 329 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 34 323 7.4E-77 T 12-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MIM_c13510 85f6db374b6926e23040be4bcb2edf6c 329 Gene3D G3DSA:3.30.2350.10 94 313 6.6E-63 T 12-10-2018 MIM_c13510 85f6db374b6926e23040be4bcb2edf6c 329 Gene3D G3DSA:3.10.290.10 25 93 1.4E-14 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MIM_c13510 85f6db374b6926e23040be4bcb2edf6c 329 Pfam PF01479 S4 domain 37 81 3.8E-8 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c13510 85f6db374b6926e23040be4bcb2edf6c 329 SUPERFAMILY SSF55120 97 327 4.32E-68 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MIM_c13510 85f6db374b6926e23040be4bcb2edf6c 329 SUPERFAMILY SSF55174 37 88 2.19E-9 T 12-10-2018 MIM_c13510 85f6db374b6926e23040be4bcb2edf6c 329 Pfam PF00849 RNA pseudouridylate synthase 111 267 1.8E-31 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MIM_c19200 2d167954384f0c8f573cfb3ed147d133 900 SUPERFAMILY SSF52518 483 710 4.71E-97 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c19200 2d167954384f0c8f573cfb3ed147d133 900 Gene3D G3DSA:3.40.50.920 717 900 8.0E-74 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MIM_c19200 2d167954384f0c8f573cfb3ed147d133 900 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 12 899 0.0 T 12-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 MIM_c19200 2d167954384f0c8f573cfb3ed147d133 900 Gene3D G3DSA:3.40.50.970 62 480 1.1E-130 T 12-10-2018 MIM_c19200 2d167954384f0c8f573cfb3ed147d133 900 SUPERFAMILY SSF52922 713 898 1.79E-58 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MIM_c19200 2d167954384f0c8f573cfb3ed147d133 900 PIRSF PIRSF000156 3 900 0.0 T 12-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 MIM_c19200 2d167954384f0c8f573cfb3ed147d133 900 Gene3D G3DSA:3.40.50.970 481 716 1.7E-108 T 12-10-2018 MIM_c19200 2d167954384f0c8f573cfb3ed147d133 900 SUPERFAMILY SSF52518 63 477 3.19E-138 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c19200 2d167954384f0c8f573cfb3ed147d133 900 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 147 301 2.9E-10 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MIM_c34440 65224a48e5541367b6a14ee46532ad9e 1001 SMART SM01008 30 141 2.0E-41 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MIM_c34440 65224a48e5541367b6a14ee46532ad9e 1001 SUPERFAMILY SSF56003 133 809 1.96E-156 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 MIM_c34440 65224a48e5541367b6a14ee46532ad9e 1001 Gene3D G3DSA:3.30.365.10 30 295 6.5E-97 T 12-10-2018 MIM_c34440 65224a48e5541367b6a14ee46532ad9e 1001 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 31 141 1.6E-25 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MIM_c34440 65224a48e5541367b6a14ee46532ad9e 1001 SUPERFAMILY SSF54665 14 162 1.44E-40 T 12-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily MIM_c34440 65224a48e5541367b6a14ee46532ad9e 1001 Gene3D G3DSA:3.30.365.10 467 661 4.3E-115 T 12-10-2018 MIM_c34440 65224a48e5541367b6a14ee46532ad9e 1001 Gene3D G3DSA:3.90.1170.50 46 141 6.5E-97 T 12-10-2018 MIM_c34440 65224a48e5541367b6a14ee46532ad9e 1001 Gene3D G3DSA:3.30.365.10 380 786 4.3E-115 T 12-10-2018 MIM_c34440 65224a48e5541367b6a14ee46532ad9e 1001 Gene3D G3DSA:3.30.530.20 834 982 1.5E-34 T 12-10-2018 IPR023393 START-like domain superfamily MIM_c34440 65224a48e5541367b6a14ee46532ad9e 1001 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 157 746 3.7E-143 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MIM_c34440 65224a48e5541367b6a14ee46532ad9e 1001 Gene3D G3DSA:3.30.365.10 142 372 6.5E-97 T 12-10-2018 MIM_c34440 65224a48e5541367b6a14ee46532ad9e 1001 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 839 977 2.3E-30 T 12-10-2018 IPR010419 Carbon monoxide dehydrogenase subunit G MIM_c34440 65224a48e5541367b6a14ee46532ad9e 1001 SUPERFAMILY SSF55961 838 976 4.07E-32 T 12-10-2018 MIM_c04860 f6fba304adcfa68b5e726a1d3f4ff924 195 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 195 42.282 T 12-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MIM_c04860 f6fba304adcfa68b5e726a1d3f4ff924 195 Gene3D G3DSA:3.30.230.40 1 89 9.4E-38 T 12-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 MIM_c04860 f6fba304adcfa68b5e726a1d3f4ff924 195 Gene3D G3DSA:3.30.230.40 90 195 1.5E-38 T 12-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 MIM_c04860 f6fba304adcfa68b5e726a1d3f4ff924 195 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 61 74 - T 12-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MIM_c04860 f6fba304adcfa68b5e726a1d3f4ff924 195 SUPERFAMILY SSF54211 1 86 1.77E-34 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MIM_c04860 f6fba304adcfa68b5e726a1d3f4ff924 195 SUPERFAMILY SSF54211 88 178 1.39E-33 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MIM_c04860 f6fba304adcfa68b5e726a1d3f4ff924 195 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 31 174 5.3E-62 T 12-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MIM_c04860 f6fba304adcfa68b5e726a1d3f4ff924 195 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 156 168 - T 12-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MIM_c32100 cd36b3e419f47502daf7757253d6817b 331 SUPERFAMILY SSF55326 3 136 4.36E-32 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MIM_c32100 cd36b3e419f47502daf7757253d6817b 331 SUPERFAMILY SSF56042 140 307 2.69E-28 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MIM_c32100 cd36b3e419f47502daf7757253d6817b 331 Pfam PF00586 AIR synthase related protein, N-terminal domain 25 136 3.7E-24 T 12-10-2018 IPR016188 PurM-like, N-terminal domain MIM_c32100 cd36b3e419f47502daf7757253d6817b 331 Pfam PF02769 AIR synthase related protein, C-terminal domain 148 305 1.5E-6 T 12-10-2018 IPR010918 PurM-like, C-terminal domain MIM_c32100 cd36b3e419f47502daf7757253d6817b 331 PIRSF PIRSF005303 1 323 1.0E-80 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 MIM_c32100 cd36b3e419f47502daf7757253d6817b 331 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 3 323 4.3E-95 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 MIM_c32100 cd36b3e419f47502daf7757253d6817b 331 Gene3D G3DSA:3.90.650.10 142 323 4.4E-44 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MIM_c32100 cd36b3e419f47502daf7757253d6817b 331 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 2 323 26.11 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 MIM_c32100 cd36b3e419f47502daf7757253d6817b 331 Gene3D G3DSA:3.30.1330.10 1 139 4.4E-44 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MIM_c33890 f1359cc671ab86ee24ac13639dbfee01 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 280 1.6E-26 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c33890 f1359cc671ab86ee24ac13639dbfee01 293 SUPERFAMILY SSF161098 86 268 1.26E-32 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c33890 f1359cc671ab86ee24ac13639dbfee01 293 Gene3D G3DSA:1.10.3720.10 84 280 4.0E-25 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c03130 0603a3b3a7c42f7cf71766ebb54508ce 337 Pfam PF00005 ABC transporter 47 197 6.0E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c03130 0603a3b3a7c42f7cf71766ebb54508ce 337 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 249 313 5.8E-20 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c03130 0603a3b3a7c42f7cf71766ebb54508ce 337 Gene3D G3DSA:3.40.50.300 10 337 2.5E-101 T 12-10-2018 MIM_c03130 0603a3b3a7c42f7cf71766ebb54508ce 337 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 247 333 3.9E-29 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c03130 0603a3b3a7c42f7cf71766ebb54508ce 337 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c03130 0603a3b3a7c42f7cf71766ebb54508ce 337 SMART SM00382 55 247 8.3E-19 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c03130 0603a3b3a7c42f7cf71766ebb54508ce 337 SUPERFAMILY SSF52540 55 322 2.33E-72 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c25610 2ab196e855cae79afe47b791f685c23d 727 Gene3D G3DSA:2.40.170.20 196 727 2.1E-83 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MIM_c25610 2ab196e855cae79afe47b791f685c23d 727 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 710 727 - T 12-10-2018 IPR010917 TonB-dependent receptor, conserved site MIM_c25610 2ab196e855cae79afe47b791f685c23d 727 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 92 727 2.6E-111 T 12-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 MIM_c25610 2ab196e855cae79afe47b791f685c23d 727 Gene3D G3DSA:2.170.130.10 77 195 2.6E-20 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MIM_c25610 2ab196e855cae79afe47b791f685c23d 727 Pfam PF00593 TonB dependent receptor 272 725 2.3E-40 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MIM_c25610 2ab196e855cae79afe47b791f685c23d 727 SUPERFAMILY SSF56935 74 727 1.96E-108 T 12-10-2018 MIM_c25610 2ab196e855cae79afe47b791f685c23d 727 Pfam PF07715 TonB-dependent Receptor Plug Domain 82 179 5.0E-16 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain MIM_c12190 d9ffc422482c3bbe6b45cc587404a5c8 720 Gene3D G3DSA:2.40.50.140 627 698 2.4E-26 T 12-10-2018 MIM_c12190 d9ffc422482c3bbe6b45cc587404a5c8 720 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 325 1.3E-18 T 12-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MIM_c12190 d9ffc422482c3bbe6b45cc587404a5c8 720 SUPERFAMILY SSF46915 239 326 3.92E-16 T 12-10-2018 IPR036456 Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MIM_c12190 d9ffc422482c3bbe6b45cc587404a5c8 720 SUPERFAMILY SSF54791 560 644 3.34E-21 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 MIM_c12190 d9ffc422482c3bbe6b45cc587404a5c8 720 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 10 696 0.0 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MIM_c12190 d9ffc422482c3bbe6b45cc587404a5c8 720 PIRSF PIRSF005499 1 719 5.1E-295 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MIM_c12190 d9ffc422482c3bbe6b45cc587404a5c8 720 Gene3D G3DSA:3.30.230.70 1 229 5.9E-81 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MIM_c12190 d9ffc422482c3bbe6b45cc587404a5c8 720 SUPERFAMILY SSF54211 2 144 4.76E-52 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MIM_c12190 d9ffc422482c3bbe6b45cc587404a5c8 720 Pfam PF00013 KH domain 562 619 2.6E-13 T 12-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 MIM_c12190 d9ffc422482c3bbe6b45cc587404a5c8 720 Pfam PF01138 3' exoribonuclease family, domain 1 329 461 1.5E-23 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MIM_c12190 d9ffc422482c3bbe6b45cc587404a5c8 720 Pfam PF01138 3' exoribonuclease family, domain 1 16 144 2.4E-20 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MIM_c12190 d9ffc422482c3bbe6b45cc587404a5c8 720 SMART SM00322 557 622 8.8E-16 T 12-10-2018 IPR004087 K Homology domain GO:0003676 MIM_c12190 d9ffc422482c3bbe6b45cc587404a5c8 720 Gene3D G3DSA:3.30.1370.10 555 626 4.9E-21 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 MIM_c12190 d9ffc422482c3bbe6b45cc587404a5c8 720 Pfam PF03725 3' exoribonuclease family, domain 2 466 533 3.7E-6 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MIM_c12190 d9ffc422482c3bbe6b45cc587404a5c8 720 Pfam PF03725 3' exoribonuclease family, domain 2 147 205 7.6E-13 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MIM_c12190 d9ffc422482c3bbe6b45cc587404a5c8 720 Gene3D G3DSA:3.30.230.70 232 554 8.4E-116 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MIM_c12190 d9ffc422482c3bbe6b45cc587404a5c8 720 SUPERFAMILY SSF55666 145 235 2.38E-29 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MIM_c12190 d9ffc422482c3bbe6b45cc587404a5c8 720 Pfam PF00575 S1 RNA binding domain 624 695 1.3E-16 T 12-10-2018 IPR003029 S1 domain GO:0003676 MIM_c12190 d9ffc422482c3bbe6b45cc587404a5c8 720 SUPERFAMILY SSF54211 300 493 3.8E-49 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MIM_c12190 d9ffc422482c3bbe6b45cc587404a5c8 720 SUPERFAMILY SSF50249 625 697 4.21E-18 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c12190 d9ffc422482c3bbe6b45cc587404a5c8 720 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 3 698 30.072 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MIM_c12190 d9ffc422482c3bbe6b45cc587404a5c8 720 SUPERFAMILY SSF55666 458 565 2.38E-28 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MIM_c12190 d9ffc422482c3bbe6b45cc587404a5c8 720 SMART SM00316 625 695 9.6E-23 T 12-10-2018 IPR022967 RNA-binding domain, S1 MIM_c10370 25ae732dc281915b6a91cc62f99c0207 355 SUPERFAMILY SSF51395 8 345 1.5E-94 T 12-10-2018 MIM_c10370 25ae732dc281915b6a91cc62f99c0207 355 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 85 104 - T 12-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 MIM_c10370 25ae732dc281915b6a91cc62f99c0207 355 PIRSF PIRSF000164 15 353 6.4E-95 T 12-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 MIM_c10370 25ae732dc281915b6a91cc62f99c0207 355 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 8 347 7.9E-119 T 12-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 MIM_c10370 25ae732dc281915b6a91cc62f99c0207 355 Pfam PF01180 Dihydroorotate dehydrogenase 53 345 7.7E-84 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 MIM_c10370 25ae732dc281915b6a91cc62f99c0207 355 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 7 344 48.207 T 12-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 MIM_c10370 25ae732dc281915b6a91cc62f99c0207 355 Gene3D G3DSA:3.20.20.70 7 344 5.1E-127 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c41160 8a059be8e1353b4c88c0a3f3ec42d269 294 Pfam PF03466 LysR substrate binding domain 94 293 1.7E-30 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c41160 8a059be8e1353b4c88c0a3f3ec42d269 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 64 2.0E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c41160 8a059be8e1353b4c88c0a3f3ec42d269 294 SUPERFAMILY SSF53850 95 294 5.43E-35 T 12-10-2018 MIM_c41160 8a059be8e1353b4c88c0a3f3ec42d269 294 Gene3D G3DSA:1.10.10.10 4 94 1.9E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c41160 8a059be8e1353b4c88c0a3f3ec42d269 294 Gene3D G3DSA:3.40.190.290 95 294 4.3E-28 T 12-10-2018 MIM_c41160 8a059be8e1353b4c88c0a3f3ec42d269 294 SUPERFAMILY SSF46785 5 89 1.09E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c32710 88629bd3187aa4b1aa3ead84928ab82f 243 SUPERFAMILY SSF51735 6 238 6.57E-63 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c32710 88629bd3187aa4b1aa3ead84928ab82f 243 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 179 0.0029 T 12-10-2018 MIM_c32710 88629bd3187aa4b1aa3ead84928ab82f 243 Gene3D G3DSA:3.40.50.720 2 240 1.6E-64 T 12-10-2018 MIM_c32710 88629bd3187aa4b1aa3ead84928ab82f 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 9.9E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c32710 88629bd3187aa4b1aa3ead84928ab82f 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 9.9E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c32710 88629bd3187aa4b1aa3ead84928ab82f 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 9.9E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c32710 88629bd3187aa4b1aa3ead84928ab82f 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 9.9E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c32710 88629bd3187aa4b1aa3ead84928ab82f 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 220 9.9E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c32710 88629bd3187aa4b1aa3ead84928ab82f 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 9.9E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c32710 88629bd3187aa4b1aa3ead84928ab82f 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 236 2.1E-42 T 12-10-2018 MIM_c32710 88629bd3187aa4b1aa3ead84928ab82f 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 130 158 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c30300 310be642fa1c963d96b1d35235645811 297 Gene3D G3DSA:2.40.50.100 50 121 9.2E-11 T 12-10-2018 MIM_c30300 310be642fa1c963d96b1d35235645811 297 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 50 233 4.6E-32 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MIM_c30300 310be642fa1c963d96b1d35235645811 297 SUPERFAMILY SSF111369 46 190 1.22E-22 T 12-10-2018 MIM_c30300 310be642fa1c963d96b1d35235645811 297 Pfam PF13533 Biotin-lipoyl like 51 96 1.3E-16 T 12-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain MIM_c30300 310be642fa1c963d96b1d35235645811 297 Gene3D G3DSA:2.40.30.170 174 296 3.5E-25 T 12-10-2018 MIM_c30300 310be642fa1c963d96b1d35235645811 297 Pfam PF13437 HlyD family secretion protein 160 243 4.8E-9 T 12-10-2018 MIM_c19260 e024e120636094a04d95d25521d2bb00 505 Pfam PF13522 Glutamine amidotransferase domain 66 197 1.3E-15 T 12-10-2018 MIM_c19260 e024e120636094a04d95d25521d2bb00 505 Gene3D G3DSA:3.60.20.10 2 414 3.0E-147 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MIM_c19260 e024e120636094a04d95d25521d2bb00 505 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 466 44.614 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 MIM_c19260 e024e120636094a04d95d25521d2bb00 505 SUPERFAMILY SSF53271 252 483 2.63E-69 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like MIM_c19260 e024e120636094a04d95d25521d2bb00 505 Gene3D G3DSA:3.40.50.2020 279 443 3.0E-147 T 12-10-2018 MIM_c19260 e024e120636094a04d95d25521d2bb00 505 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 466 3.5E-154 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 MIM_c19260 e024e120636094a04d95d25521d2bb00 505 PIRSF PIRSF000485 1 481 1.4E-154 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 MIM_c19260 e024e120636094a04d95d25521d2bb00 505 SUPERFAMILY SSF56235 2 259 1.8E-66 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MIM_c19260 e024e120636094a04d95d25521d2bb00 505 Pfam PF00156 Phosphoribosyl transferase domain 285 394 3.3E-9 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MIM_c07380 523423dc5e70c4632f5b86ad3a6abbec 138 Pfam PF00581 Rhodanese-like domain 39 130 2.9E-13 T 12-10-2018 IPR001763 Rhodanese-like domain MIM_c07380 523423dc5e70c4632f5b86ad3a6abbec 138 Gene3D G3DSA:3.40.250.10 42 138 3.1E-25 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily MIM_c07380 523423dc5e70c4632f5b86ad3a6abbec 138 SMART SM00450 38 133 1.5E-17 T 12-10-2018 IPR001763 Rhodanese-like domain MIM_c07380 523423dc5e70c4632f5b86ad3a6abbec 138 SUPERFAMILY SSF52821 18 136 9.56E-28 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily MIM_c05440 e561eba9bbe884d15948e37385c80393 242 Pfam PF13419 Haloacid dehalogenase-like hydrolase 24 204 6.8E-13 T 12-10-2018 MIM_c05440 e561eba9bbe884d15948e37385c80393 242 TIGRFAM TIGR01993 Pyr-5-nucltdase: pyrimidine 5'-nucleotidase 22 204 2.5E-46 T 12-10-2018 IPR010237 Pyrimidine 5-nucleotidase MIM_c05440 e561eba9bbe884d15948e37385c80393 242 SUPERFAMILY SSF56784 21 233 5.05E-27 T 12-10-2018 IPR036412 HAD-like superfamily MIM_c05440 e561eba9bbe884d15948e37385c80393 242 Gene3D G3DSA:3.40.50.1000 99 236 1.0E-17 T 12-10-2018 IPR023214 HAD superfamily MIM_c05440 e561eba9bbe884d15948e37385c80393 242 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 160 205 2.4E-9 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MIM_c05440 e561eba9bbe884d15948e37385c80393 242 Gene3D G3DSA:1.10.150.450 22 96 4.7E-9 T 12-10-2018 MIM_c08500 e707f19ce39014c537f0ff2f3dfa6b62 302 Gene3D G3DSA:1.10.10.10 1 87 6.1E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c08500 e707f19ce39014c537f0ff2f3dfa6b62 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c08500 e707f19ce39014c537f0ff2f3dfa6b62 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c08500 e707f19ce39014c537f0ff2f3dfa6b62 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c08500 e707f19ce39014c537f0ff2f3dfa6b62 302 SUPERFAMILY SSF53850 87 282 2.71E-26 T 12-10-2018 MIM_c08500 e707f19ce39014c537f0ff2f3dfa6b62 302 SUPERFAMILY SSF46785 1 111 1.11E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c08500 e707f19ce39014c537f0ff2f3dfa6b62 302 Pfam PF03466 LysR substrate binding domain 88 275 4.8E-28 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c08500 e707f19ce39014c537f0ff2f3dfa6b62 302 Gene3D G3DSA:3.40.190.10 164 264 3.2E-19 T 12-10-2018 MIM_c08500 e707f19ce39014c537f0ff2f3dfa6b62 302 Gene3D G3DSA:3.40.190.10 91 270 3.2E-19 T 12-10-2018 MIM_c08500 e707f19ce39014c537f0ff2f3dfa6b62 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 2.9E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c13720 972ec1dee5bf7e0a405040cf3a56f8b5 308 Pfam PF13460 NAD(P)H-binding 63 242 3.9E-32 T 12-10-2018 IPR016040 NAD(P)-binding domain MIM_c13720 972ec1dee5bf7e0a405040cf3a56f8b5 308 Gene3D G3DSA:3.40.50.720 55 271 1.5E-43 T 12-10-2018 MIM_c13720 972ec1dee5bf7e0a405040cf3a56f8b5 308 SUPERFAMILY SSF51735 56 256 2.77E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c20870 59fa353955f4dd9c3ac75fd8f2bd6ebf 267 Gene3D G3DSA:1.10.12.10 203 259 6.1E-10 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MIM_c20870 59fa353955f4dd9c3ac75fd8f2bd6ebf 267 SUPERFAMILY SSF52096 2 259 1.17E-68 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c20870 59fa353955f4dd9c3ac75fd8f2bd6ebf 267 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 258 9.2E-48 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c20870 59fa353955f4dd9c3ac75fd8f2bd6ebf 267 Gene3D G3DSA:3.90.226.10 1 200 3.8E-56 T 12-10-2018 MIM_c05990 e18900b6a1e4be84be64162f91deb0da 265 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 22 261 2.8E-62 T 12-10-2018 MIM_c05990 e18900b6a1e4be84be64162f91deb0da 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 2.1E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c05990 e18900b6a1e4be84be64162f91deb0da 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 2.1E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c05990 e18900b6a1e4be84be64162f91deb0da 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 2.1E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c05990 e18900b6a1e4be84be64162f91deb0da 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 7.8E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c05990 e18900b6a1e4be84be64162f91deb0da 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 7.8E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c05990 e18900b6a1e4be84be64162f91deb0da 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 7.8E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c05990 e18900b6a1e4be84be64162f91deb0da 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 7.8E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c05990 e18900b6a1e4be84be64162f91deb0da 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 7.8E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c05990 e18900b6a1e4be84be64162f91deb0da 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 7.8E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c05990 e18900b6a1e4be84be64162f91deb0da 265 Gene3D G3DSA:3.40.50.720 1 265 1.3E-83 T 12-10-2018 MIM_c05990 e18900b6a1e4be84be64162f91deb0da 265 SUPERFAMILY SSF51735 1 262 1.33E-75 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c08230 c0462bb430c633ea95532f4c4aa06bf9 306 Gene3D G3DSA:1.10.10.10 1 89 6.9E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c08230 c0462bb430c633ea95532f4c4aa06bf9 306 Gene3D G3DSA:3.40.190.290 91 298 4.7E-29 T 12-10-2018 MIM_c08230 c0462bb430c633ea95532f4c4aa06bf9 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 1.6E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c08230 c0462bb430c633ea95532f4c4aa06bf9 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c08230 c0462bb430c633ea95532f4c4aa06bf9 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c08230 c0462bb430c633ea95532f4c4aa06bf9 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c08230 c0462bb430c633ea95532f4c4aa06bf9 306 SUPERFAMILY SSF46785 1 87 5.99E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c08230 c0462bb430c633ea95532f4c4aa06bf9 306 Pfam PF03466 LysR substrate binding domain 88 289 2.7E-29 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c08230 c0462bb430c633ea95532f4c4aa06bf9 306 SUPERFAMILY SSF53850 88 296 7.28E-33 T 12-10-2018 MIM_c05120 dd0f32eef70a21c519b182e733da127e 240 Gene3D G3DSA:3.40.50.300 1 235 1.9E-50 T 12-10-2018 MIM_c05120 dd0f32eef70a21c519b182e733da127e 240 SMART SM00382 33 214 5.4E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c05120 dd0f32eef70a21c519b182e733da127e 240 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c05120 dd0f32eef70a21c519b182e733da127e 240 SUPERFAMILY SSF52540 5 228 1.64E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c05120 dd0f32eef70a21c519b182e733da127e 240 Pfam PF00005 ABC transporter 25 165 1.1E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c11930 d4af5477099f5b60c6e6198739946193 737 Gene3D G3DSA:2.170.130.10 39 164 6.0E-21 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MIM_c11930 d4af5477099f5b60c6e6198739946193 737 Pfam PF07715 TonB-dependent Receptor Plug Domain 58 159 1.9E-16 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain MIM_c11930 d4af5477099f5b60c6e6198739946193 737 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 58 737 1.3E-66 T 12-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 MIM_c11930 d4af5477099f5b60c6e6198739946193 737 Pfam PF00593 TonB dependent receptor 250 735 7.0E-27 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MIM_c11930 d4af5477099f5b60c6e6198739946193 737 SUPERFAMILY SSF56935 36 737 2.53E-83 T 12-10-2018 MIM_c11930 d4af5477099f5b60c6e6198739946193 737 Gene3D G3DSA:2.40.170.20 172 737 3.8E-45 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MIM_c27510 e08db43571010250741d7501700255e2 250 Gene3D G3DSA:3.40.190.10 28 246 1.4E-54 T 12-10-2018 MIM_c27510 e08db43571010250741d7501700255e2 250 SMART SM00062 26 250 5.1E-46 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c27510 e08db43571010250741d7501700255e2 250 Gene3D G3DSA:3.40.190.10 113 207 1.4E-54 T 12-10-2018 MIM_c27510 e08db43571010250741d7501700255e2 250 SUPERFAMILY SSF53850 3 247 1.23E-56 T 12-10-2018 MIM_c27510 e08db43571010250741d7501700255e2 250 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 28 247 1.8E-53 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c27800 b465295d18d1bfa4454016c732daab6c 684 Pfam PF02779 Transketolase, pyrimidine binding domain 363 546 2.2E-43 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MIM_c27800 b465295d18d1bfa4454016c732daab6c 684 ProSitePatterns PS00801 Transketolase signature 1. 17 37 - T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MIM_c27800 b465295d18d1bfa4454016c732daab6c 684 SUPERFAMILY SSF52518 343 549 2.9E-62 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c27800 b465295d18d1bfa4454016c732daab6c 684 Pfam PF02780 Transketolase, C-terminal domain 563 676 1.3E-15 T 12-10-2018 IPR033248 Transketolase, C-terminal domain MIM_c27800 b465295d18d1bfa4454016c732daab6c 684 Gene3D G3DSA:3.40.50.970 336 560 3.2E-80 T 12-10-2018 MIM_c27800 b465295d18d1bfa4454016c732daab6c 684 TIGRFAM TIGR00232 tktlase_bact: transketolase 13 683 1.9E-283 T 12-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 MIM_c27800 b465295d18d1bfa4454016c732daab6c 684 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 10 343 2.9E-155 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MIM_c27800 b465295d18d1bfa4454016c732daab6c 684 Gene3D G3DSA:3.40.50.920 562 684 3.3E-44 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MIM_c27800 b465295d18d1bfa4454016c732daab6c 684 SUPERFAMILY SSF52922 556 684 2.09E-45 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MIM_c27800 b465295d18d1bfa4454016c732daab6c 684 Gene3D G3DSA:3.40.50.970 8 335 2.0E-127 T 12-10-2018 MIM_c27800 b465295d18d1bfa4454016c732daab6c 684 SMART SM00861 364 548 5.7E-68 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MIM_c27800 b465295d18d1bfa4454016c732daab6c 684 SUPERFAMILY SSF52518 12 329 7.23E-114 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c02790 d67c6a9f3beb83875f184a4241c0dbee 162 Pfam PF00583 Acetyltransferase (GNAT) family 49 140 2.3E-14 T 12-10-2018 IPR000182 GNAT domain MIM_c02790 d67c6a9f3beb83875f184a4241c0dbee 162 SUPERFAMILY SSF55729 11 157 9.45E-28 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c02790 d67c6a9f3beb83875f184a4241c0dbee 162 Gene3D G3DSA:3.40.630.30 11 148 1.4E-27 T 12-10-2018 MIM_c23520 40f6a56bbe6e6bc7ccb6335db898d0ee 299 SUPERFAMILY SSF53850 92 296 7.06E-44 T 12-10-2018 MIM_c23520 40f6a56bbe6e6bc7ccb6335db898d0ee 299 Gene3D G3DSA:1.10.10.10 4 91 1.5E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c23520 40f6a56bbe6e6bc7ccb6335db898d0ee 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 5.4E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c23520 40f6a56bbe6e6bc7ccb6335db898d0ee 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 5.4E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c23520 40f6a56bbe6e6bc7ccb6335db898d0ee 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 5.4E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c23520 40f6a56bbe6e6bc7ccb6335db898d0ee 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 9.2E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c23520 40f6a56bbe6e6bc7ccb6335db898d0ee 299 SUPERFAMILY SSF46785 4 113 3.25E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c23520 40f6a56bbe6e6bc7ccb6335db898d0ee 299 Pfam PF03466 LysR substrate binding domain 92 293 1.9E-45 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c23520 40f6a56bbe6e6bc7ccb6335db898d0ee 299 Gene3D G3DSA:3.40.190.290 94 298 1.1E-38 T 12-10-2018 MIM_c32460 95d82f5d30772455edeb84192ddbed1e 203 SUPERFAMILY SSF89392 24 199 1.53E-25 T 12-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX MIM_c32460 95d82f5d30772455edeb84192ddbed1e 203 Pfam PF03550 Outer membrane lipoprotein LolB 44 198 3.5E-28 T 12-10-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 MIM_c32460 95d82f5d30772455edeb84192ddbed1e 203 Gene3D G3DSA:2.50.20.10 27 202 2.4E-26 T 12-10-2018 MIM_c04910 3f87e1fed94db799f4760b9da31687c2 117 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 11 100 20.815 T 12-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 MIM_c04910 3f87e1fed94db799f4760b9da31687c2 117 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 32 103 1.9E-14 T 12-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 MIM_c04910 3f87e1fed94db799f4760b9da31687c2 117 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 14 100 8.7E-29 T 12-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 MIM_c04910 3f87e1fed94db799f4760b9da31687c2 117 SUPERFAMILY SSF101386 16 104 1.66E-23 T 12-10-2018 MIM_c04910 3f87e1fed94db799f4760b9da31687c2 117 Gene3D G3DSA:1.10.287.1080 10 105 9.4E-29 T 12-10-2018 MIM_c00190 4df2ba7edef53df34d9c76e77c836471 145 Gene3D G3DSA:1.20.1290.10 1 145 1.7E-54 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c00190 4df2ba7edef53df34d9c76e77c836471 145 SUPERFAMILY SSF69118 3 144 1.92E-51 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c00190 4df2ba7edef53df34d9c76e77c836471 145 Pfam PF02627 Carboxymuconolactone decarboxylase family 12 93 3.3E-22 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c00190 4df2ba7edef53df34d9c76e77c836471 145 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 29 77 1.7E-19 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c01020 596182e06792b5dff64018b74451d848 634 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 227 633 2.4E-87 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 MIM_c01020 596182e06792b5dff64018b74451d848 634 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 217 629 9.4E-94 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit MIM_c01020 596182e06792b5dff64018b74451d848 634 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 52 176 1.3E-24 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ MIM_c40680 245d8d22a0727b5a4e8381c2d808441f 177 SMART SM00739 123 150 4.4E-4 T 12-10-2018 IPR005824 KOW MIM_c40680 245d8d22a0727b5a4e8381c2d808441f 177 SUPERFAMILY SSF82679 3 113 4.45E-37 T 12-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MIM_c40680 245d8d22a0727b5a4e8381c2d808441f 177 SUPERFAMILY SSF50104 121 176 7.02E-19 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily MIM_c40680 245d8d22a0727b5a4e8381c2d808441f 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 25.307 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MIM_c40680 245d8d22a0727b5a4e8381c2d808441f 177 Gene3D G3DSA:2.30.30.30 120 176 3.6E-26 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 MIM_c40680 245d8d22a0727b5a4e8381c2d808441f 177 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 2.4E-20 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MIM_c40680 245d8d22a0727b5a4e8381c2d808441f 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 2.4E-20 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MIM_c40680 245d8d22a0727b5a4e8381c2d808441f 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 2.4E-20 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MIM_c40680 245d8d22a0727b5a4e8381c2d808441f 177 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 12-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site MIM_c40680 245d8d22a0727b5a4e8381c2d808441f 177 Gene3D G3DSA:3.30.70.940 1 119 8.1E-46 T 12-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MIM_c40680 245d8d22a0727b5a4e8381c2d808441f 177 Pfam PF02357 Transcription termination factor nusG 3 108 9.0E-27 T 12-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MIM_c40680 245d8d22a0727b5a4e8381c2d808441f 177 SMART SM00738 2 111 4.5E-46 T 12-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MIM_c40680 245d8d22a0727b5a4e8381c2d808441f 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 176 4.6E-68 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MIM_c34970 f2cdfea16b14d39b54291c771c97fdbe 398 Gene3D G3DSA:2.40.110.10 116 217 5.8E-26 T 12-10-2018 MIM_c34970 f2cdfea16b14d39b54291c771c97fdbe 398 PIRSF PIRSF016578 2 390 1.5E-21 T 12-10-2018 MIM_c34970 f2cdfea16b14d39b54291c771c97fdbe 398 SUPERFAMILY SSF47203 231 374 2.26E-10 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c34970 f2cdfea16b14d39b54291c771c97fdbe 398 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 237 373 4.8E-9 T 12-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain MIM_c34970 f2cdfea16b14d39b54291c771c97fdbe 398 SUPERFAMILY SSF56645 13 217 3.4E-32 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c34970 f2cdfea16b14d39b54291c771c97fdbe 398 Gene3D G3DSA:1.20.140.10 219 397 1.7E-39 T 12-10-2018 MIM_c34970 f2cdfea16b14d39b54291c771c97fdbe 398 Gene3D G3DSA:1.10.540.10 10 103 1.5E-13 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c11260 46d7d4068f09c60ec8f715c739831779 420 Gene3D G3DSA:3.40.190.10 39 376 1.2E-75 T 12-10-2018 MIM_c11260 46d7d4068f09c60ec8f715c739831779 420 SUPERFAMILY SSF53850 24 419 2.57E-59 T 12-10-2018 MIM_c11260 46d7d4068f09c60ec8f715c739831779 420 Pfam PF13416 Bacterial extracellular solute-binding protein 45 343 1.6E-33 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein MIM_c11260 46d7d4068f09c60ec8f715c739831779 420 Gene3D G3DSA:3.40.190.10 144 413 1.2E-75 T 12-10-2018 MIM_c27830 477c5d4565732bdc79916edd5bb2220b 155 Pfam PF01337 Barstar (barnase inhibitor) 43 124 1.9E-16 T 12-10-2018 IPR000468 Barstar (barnase inhibitor) MIM_c27830 477c5d4565732bdc79916edd5bb2220b 155 SUPERFAMILY SSF52038 41 129 4.05E-12 T 12-10-2018 IPR035905 Barstar-like superfamily MIM_c27830 477c5d4565732bdc79916edd5bb2220b 155 Gene3D G3DSA:3.30.370.10 42 126 2.4E-5 T 12-10-2018 IPR035905 Barstar-like superfamily MIM_c01700 2ff063136df97bec03453ea24aaaa26a 316 Gene3D G3DSA:3.40.190.290 92 296 8.2E-32 T 12-10-2018 MIM_c01700 2ff063136df97bec03453ea24aaaa26a 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.7E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c01700 2ff063136df97bec03453ea24aaaa26a 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.7E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c01700 2ff063136df97bec03453ea24aaaa26a 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.7E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c01700 2ff063136df97bec03453ea24aaaa26a 316 Pfam PF03466 LysR substrate binding domain 87 291 8.0E-32 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c01700 2ff063136df97bec03453ea24aaaa26a 316 SUPERFAMILY SSF53850 89 295 4.46E-31 T 12-10-2018 MIM_c01700 2ff063136df97bec03453ea24aaaa26a 316 Gene3D G3DSA:1.10.10.10 1 90 8.2E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c01700 2ff063136df97bec03453ea24aaaa26a 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 7.1E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c01700 2ff063136df97bec03453ea24aaaa26a 316 SUPERFAMILY SSF46785 1 83 3.48E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c28990 49a093113492b302678c549a9a09e95a 331 SUPERFAMILY SSF54909 8 310 1.02E-108 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel MIM_c28990 49a093113492b302678c549a9a09e95a 331 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 9 305 2.5E-89 T 12-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 MIM_c28990 49a093113492b302678c549a9a09e95a 331 Pfam PF04261 Dyp-type peroxidase family 9 304 5.7E-98 T 12-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 MIM_c14290 7f8265a389c3157cf0a52a36476c4cee 358 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 100 114 9.6E-13 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MIM_c14290 7f8265a389c3157cf0a52a36476c4cee 358 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 31 39 9.6E-13 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MIM_c14290 7f8265a389c3157cf0a52a36476c4cee 358 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 57 68 9.6E-13 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MIM_c14290 7f8265a389c3157cf0a52a36476c4cee 358 SUPERFAMILY SSF53474 4 328 3.71E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c14290 7f8265a389c3157cf0a52a36476c4cee 358 PIRSF PIRSF006431 1 222 2.6E-67 T 12-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 MIM_c14290 7f8265a389c3157cf0a52a36476c4cee 358 PIRSF PIRSF006431 222 348 5.5E-12 T 12-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 MIM_c14290 7f8265a389c3157cf0a52a36476c4cee 358 Pfam PF00561 alpha/beta hydrolase fold 29 328 9.1E-27 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c38330 4073f9c18ef11067e57b92d89b7517dd 319 SUPERFAMILY SSF47203 180 299 2.26E-21 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c38330 4073f9c18ef11067e57b92d89b7517dd 319 Gene3D G3DSA:1.20.140.10 174 308 2.3E-22 T 12-10-2018 MIM_c38330 4073f9c18ef11067e57b92d89b7517dd 319 Gene3D G3DSA:1.10.540.10 5 102 2.1E-7 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c38330 4073f9c18ef11067e57b92d89b7517dd 319 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 190 296 6.5E-14 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MIM_c38330 4073f9c18ef11067e57b92d89b7517dd 319 SUPERFAMILY SSF56645 16 129 7.85E-9 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c39240 aef95abb515d3ace87b165138a956c77 261 SUPERFAMILY SSF55781 79 260 6.34E-38 T 12-10-2018 MIM_c39240 aef95abb515d3ace87b165138a956c77 261 Gene3D G3DSA:3.30.450.40 89 261 1.0E-36 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c39240 aef95abb515d3ace87b165138a956c77 261 Gene3D G3DSA:1.10.10.10 14 86 2.0E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c39240 aef95abb515d3ace87b165138a956c77 261 Pfam PF01614 Bacterial transcriptional regulator 133 256 1.3E-20 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal MIM_c39240 aef95abb515d3ace87b165138a956c77 261 Pfam PF09339 IclR helix-turn-helix domain 17 67 5.9E-11 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c39240 aef95abb515d3ace87b165138a956c77 261 SUPERFAMILY SSF46785 17 85 4.92E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c39240 aef95abb515d3ace87b165138a956c77 261 SMART SM00346 15 104 1.4E-14 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c31590 93b3245239abd176e9941389751aa9b4 411 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 306 3.2E-52 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MIM_c31590 93b3245239abd176e9941389751aa9b4 411 SUPERFAMILY SSF55424 318 409 3.71E-20 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MIM_c31590 93b3245239abd176e9941389751aa9b4 411 Pfam PF14759 Reductase C-terminal 326 409 4.7E-19 T 12-10-2018 IPR028202 Reductase, C-terminal MIM_c31590 93b3245239abd176e9941389751aa9b4 411 SUPERFAMILY SSF51905 3 193 3.8E-44 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c31590 93b3245239abd176e9941389751aa9b4 411 SUPERFAMILY SSF51905 148 316 2.41E-27 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c31590 93b3245239abd176e9941389751aa9b4 411 Gene3D G3DSA:3.30.390.30 326 411 1.6E-18 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MIM_c31590 93b3245239abd176e9941389751aa9b4 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 1.0E-14 T 12-10-2018 MIM_c31590 93b3245239abd176e9941389751aa9b4 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 1.0E-14 T 12-10-2018 MIM_c31590 93b3245239abd176e9941389751aa9b4 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 1.0E-14 T 12-10-2018 MIM_c31590 93b3245239abd176e9941389751aa9b4 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 1.0E-14 T 12-10-2018 MIM_c31590 93b3245239abd176e9941389751aa9b4 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.0E-14 T 12-10-2018 MIM_c31590 93b3245239abd176e9941389751aa9b4 411 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 237 251 1.6E-14 T 12-10-2018 MIM_c31590 93b3245239abd176e9941389751aa9b4 411 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.6E-14 T 12-10-2018 MIM_c31590 93b3245239abd176e9941389751aa9b4 411 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 148 173 1.6E-14 T 12-10-2018 MIM_c31590 93b3245239abd176e9941389751aa9b4 411 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 277 284 1.6E-14 T 12-10-2018 MIM_c31590 93b3245239abd176e9941389751aa9b4 411 Gene3D G3DSA:3.50.50.60 8 312 5.3E-92 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c31590 93b3245239abd176e9941389751aa9b4 411 Gene3D G3DSA:3.50.50.60 116 243 5.3E-92 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c13970 7cec6c0223560aba87df39ac16fd7d2c 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 257 264 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MIM_c13970 7cec6c0223560aba87df39ac16fd7d2c 486 Gene3D G3DSA:3.40.309.10 262 451 3.1E-144 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MIM_c13970 7cec6c0223560aba87df39ac16fd7d2c 486 Pfam PF00171 Aldehyde dehydrogenase family 27 480 4.4E-134 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c13970 7cec6c0223560aba87df39ac16fd7d2c 486 SUPERFAMILY SSF53720 12 481 2.36E-132 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c13970 7cec6c0223560aba87df39ac16fd7d2c 486 Gene3D G3DSA:3.40.605.10 23 477 3.1E-144 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c06090 22a24c884a333bb2e81b231590f4a347 149 TIGRFAM TIGR03293 PhnG_redo: phosphonate C-P lyase system protein PhnG 9 147 9.5E-50 T 12-10-2018 IPR009609 Phosphonate metabolism PhnG GO:0015716|GO:0019634 KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 MIM_c06090 22a24c884a333bb2e81b231590f4a347 149 Pfam PF06754 Phosphonate metabolism protein PhnG 9 146 1.7E-52 T 12-10-2018 IPR009609 Phosphonate metabolism PhnG GO:0015716|GO:0019634 KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 MIM_c01880 089b5a31c13693df44a42595698775a1 415 Gene3D G3DSA:1.20.1250.20 6 405 1.2E-44 T 12-10-2018 MIM_c01880 089b5a31c13693df44a42595698775a1 415 Pfam PF07690 Major Facilitator Superfamily 17 339 2.1E-27 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c01880 089b5a31c13693df44a42595698775a1 415 SUPERFAMILY SSF103473 5 402 2.88E-58 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c30910 3b92fec5c1f2c922b8cf85735727de06 293 Gene3D G3DSA:1.10.10.10 1 91 5.3E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c30910 3b92fec5c1f2c922b8cf85735727de06 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.9E-11 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c30910 3b92fec5c1f2c922b8cf85735727de06 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.9E-11 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c30910 3b92fec5c1f2c922b8cf85735727de06 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.9E-11 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c30910 3b92fec5c1f2c922b8cf85735727de06 293 SUPERFAMILY SSF46785 1 86 5.46E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c30910 3b92fec5c1f2c922b8cf85735727de06 293 Pfam PF03466 LysR substrate binding domain 95 289 1.0E-40 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c30910 3b92fec5c1f2c922b8cf85735727de06 293 SUPERFAMILY SSF53850 95 289 2.39E-36 T 12-10-2018 MIM_c30910 3b92fec5c1f2c922b8cf85735727de06 293 Gene3D G3DSA:3.40.190.10 163 267 1.3E-67 T 12-10-2018 MIM_c30910 3b92fec5c1f2c922b8cf85735727de06 293 Gene3D G3DSA:3.40.190.10 95 286 1.3E-67 T 12-10-2018 MIM_c30910 3b92fec5c1f2c922b8cf85735727de06 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.3E-23 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c34420 3de5154377a1bd74ae7512aaadd5a20d 170 Gene3D G3DSA:1.10.150.120 83 170 1.2E-29 T 12-10-2018 MIM_c34420 3de5154377a1bd74ae7512aaadd5a20d 170 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 14 60 4.8E-5 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MIM_c34420 3de5154377a1bd74ae7512aaadd5a20d 170 Gene3D G3DSA:3.10.20.30 1 82 2.3E-26 T 12-10-2018 IPR012675 Beta-grasp domain superfamily MIM_c34420 3de5154377a1bd74ae7512aaadd5a20d 170 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 46 54 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MIM_c34420 3de5154377a1bd74ae7512aaadd5a20d 170 SUPERFAMILY SSF54292 8 84 8.65E-22 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MIM_c34420 3de5154377a1bd74ae7512aaadd5a20d 170 SUPERFAMILY SSF47741 92 164 2.88E-31 T 12-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily MIM_c34420 3de5154377a1bd74ae7512aaadd5a20d 170 Pfam PF01799 [2Fe-2S] binding domain 80 153 3.3E-26 T 12-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 MIM_c22660 ff880eb6c97cf1d4da5322ffb5b456f8 252 SMART SM00100 24 145 9.1E-7 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain MIM_c22660 ff880eb6c97cf1d4da5322ffb5b456f8 252 SUPERFAMILY SSF51206 17 156 1.13E-28 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like MIM_c22660 ff880eb6c97cf1d4da5322ffb5b456f8 252 ProSitePatterns PS00042 Crp-type HTH domain signature. 189 212 - T 12-10-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 MIM_c22660 ff880eb6c97cf1d4da5322ffb5b456f8 252 SUPERFAMILY SSF46785 161 242 1.33E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c22660 ff880eb6c97cf1d4da5322ffb5b456f8 252 Gene3D G3DSA:2.60.120.10 37 157 2.6E-34 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c22660 ff880eb6c97cf1d4da5322ffb5b456f8 252 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 203 218 5.8E-13 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MIM_c22660 ff880eb6c97cf1d4da5322ffb5b456f8 252 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 187 203 5.8E-13 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MIM_c22660 ff880eb6c97cf1d4da5322ffb5b456f8 252 SMART SM00419 181 229 1.9E-17 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MIM_c22660 ff880eb6c97cf1d4da5322ffb5b456f8 252 Gene3D G3DSA:1.10.10.10 160 243 2.9E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c22660 ff880eb6c97cf1d4da5322ffb5b456f8 252 Pfam PF13545 Crp-like helix-turn-helix domain 162 235 3.2E-19 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MIM_c22660 ff880eb6c97cf1d4da5322ffb5b456f8 252 Pfam PF00027 Cyclic nucleotide-binding domain 44 124 7.7E-13 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain MIM_c26720 fc2e9a0902f5048dd72f091f546acfff 232 Pfam PF00483 Nucleotidyl transferase 4 227 5.0E-24 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MIM_c26720 fc2e9a0902f5048dd72f091f546acfff 232 Gene3D G3DSA:3.90.550.10 2 231 4.9E-56 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MIM_c26720 fc2e9a0902f5048dd72f091f546acfff 232 SUPERFAMILY SSF53448 3 228 4.77E-55 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MIM_c10020 e936c95b70efeee6c7b1bfd5f34cb069 264 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c10020 e936c95b70efeee6c7b1bfd5f34cb069 264 SMART SM00382 25 222 3.4E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c10020 e936c95b70efeee6c7b1bfd5f34cb069 264 Gene3D G3DSA:3.40.50.300 4 262 1.3E-62 T 12-10-2018 MIM_c10020 e936c95b70efeee6c7b1bfd5f34cb069 264 Pfam PF00005 ABC transporter 16 174 2.9E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c10020 e936c95b70efeee6c7b1bfd5f34cb069 264 SUPERFAMILY SSF52540 6 241 1.03E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c00150 6d0d091bc0ace663f21d8d69b21c4d83 315 SUPERFAMILY SSF46785 8 92 5.53E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c00150 6d0d091bc0ace663f21d8d69b21c4d83 315 Gene3D G3DSA:1.10.10.10 7 95 1.3E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c00150 6d0d091bc0ace663f21d8d69b21c4d83 315 Pfam PF03466 LysR substrate binding domain 93 296 7.2E-43 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c00150 6d0d091bc0ace663f21d8d69b21c4d83 315 Gene3D G3DSA:3.40.190.290 96 296 4.5E-60 T 12-10-2018 MIM_c00150 6d0d091bc0ace663f21d8d69b21c4d83 315 SUPERFAMILY SSF53850 94 297 4.03E-45 T 12-10-2018 MIM_c00150 6d0d091bc0ace663f21d8d69b21c4d83 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 68 8.0E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c07470 8f36e46d268f340f9f7cd8da37ad5993 80 PRINTS PR00124 ATP synthase C subunit signature 10 29 1.7E-6 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07470 8f36e46d268f340f9f7cd8da37ad5993 80 PRINTS PR00124 ATP synthase C subunit signature 31 46 1.7E-6 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07470 8f36e46d268f340f9f7cd8da37ad5993 80 PRINTS PR00124 ATP synthase C subunit signature 48 73 1.7E-6 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07470 8f36e46d268f340f9f7cd8da37ad5993 80 Hamap MF_01396 ATP synthase subunit c [atpH]. 8 73 14.15 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07470 8f36e46d268f340f9f7cd8da37ad5993 80 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 19 75 2.8E-22 T 12-10-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MIM_c07470 8f36e46d268f340f9f7cd8da37ad5993 80 ProSitePatterns PS00605 ATP synthase c subunit signature. 38 59 - T 12-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07470 8f36e46d268f340f9f7cd8da37ad5993 80 Pfam PF00137 ATP synthase subunit C 9 71 3.4E-10 T 12-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 MIM_c07470 8f36e46d268f340f9f7cd8da37ad5993 80 SUPERFAMILY SSF81333 3 75 1.57E-17 T 12-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily MIM_c07470 8f36e46d268f340f9f7cd8da37ad5993 80 Gene3D G3DSA:1.20.20.10 2 76 5.7E-27 T 12-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c05250 6409c7d0417945581cd005a98fe5e6a9 196 SUPERFAMILY SSF52507 10 192 1.2E-61 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 MIM_c05250 6409c7d0417945581cd005a98fe5e6a9 196 Pfam PF02441 Flavoprotein 10 171 4.7E-25 T 12-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 MIM_c05250 6409c7d0417945581cd005a98fe5e6a9 196 Gene3D G3DSA:3.40.50.1950 9 195 2.3E-77 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 MIM_c05250 6409c7d0417945581cd005a98fe5e6a9 196 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 10 190 5.5E-72 T 12-10-2018 IPR004507 Flavin prenyltransferase UbiX-like MIM_c05250 6409c7d0417945581cd005a98fe5e6a9 196 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 9 192 36.514 T 12-10-2018 IPR004507 Flavin prenyltransferase UbiX-like MIM_c19330 3d25c5a1ff537b814f0a051220bc70d1 249 Gene3D G3DSA:1.10.287.610 98 149 3.5E-20 T 12-10-2018 MIM_c19330 3d25c5a1ff537b814f0a051220bc70d1 249 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 4 15 - T 12-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 MIM_c19330 3d25c5a1ff537b814f0a051220bc70d1 249 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 4 224 7.0E-97 T 12-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c19330 3d25c5a1ff537b814f0a051220bc70d1 249 PRINTS PR00395 Ribosomal protein S2 signature 156 173 1.9E-35 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c19330 3d25c5a1ff537b814f0a051220bc70d1 249 PRINTS PR00395 Ribosomal protein S2 signature 35 44 1.9E-35 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c19330 3d25c5a1ff537b814f0a051220bc70d1 249 PRINTS PR00395 Ribosomal protein S2 signature 85 102 1.9E-35 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c19330 3d25c5a1ff537b814f0a051220bc70d1 249 PRINTS PR00395 Ribosomal protein S2 signature 194 208 1.9E-35 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c19330 3d25c5a1ff537b814f0a051220bc70d1 249 PRINTS PR00395 Ribosomal protein S2 signature 173 184 1.9E-35 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c19330 3d25c5a1ff537b814f0a051220bc70d1 249 PRINTS PR00395 Ribosomal protein S2 signature 4 22 1.9E-35 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c19330 3d25c5a1ff537b814f0a051220bc70d1 249 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 223 38.071 T 12-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c19330 3d25c5a1ff537b814f0a051220bc70d1 249 Pfam PF00318 Ribosomal protein S2 7 222 1.2E-90 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c19330 3d25c5a1ff537b814f0a051220bc70d1 249 SUPERFAMILY SSF52313 4 228 4.58E-90 T 12-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily MIM_c10210 7ab7138ac6cbd5f2f523bd18c5034a46 529 SMART SM00798 135 461 1.3E-192 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MIM_c10210 7ab7138ac6cbd5f2f523bd18c5034a46 529 Gene3D G3DSA:3.40.140.20 394 529 1.2E-55 T 12-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MIM_c10210 7ab7138ac6cbd5f2f523bd18c5034a46 529 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 3 529 42.857 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MIM_c10210 7ab7138ac6cbd5f2f523bd18c5034a46 529 SMART SM00851 15 130 1.4E-54 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain MIM_c10210 7ab7138ac6cbd5f2f523bd18c5034a46 529 SUPERFAMILY SSF52335 3 198 2.62E-66 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily MIM_c10210 7ab7138ac6cbd5f2f523bd18c5034a46 529 Pfam PF02142 MGS-like domain 15 129 9.7E-28 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain MIM_c10210 7ab7138ac6cbd5f2f523bd18c5034a46 529 PIRSF PIRSF000414 1 529 2.5E-209 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MIM_c10210 7ab7138ac6cbd5f2f523bd18c5034a46 529 SUPERFAMILY SSF53927 223 529 1.0E-124 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 MIM_c10210 7ab7138ac6cbd5f2f523bd18c5034a46 529 Gene3D G3DSA:3.40.140.20 220 377 1.9E-58 T 12-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MIM_c10210 7ab7138ac6cbd5f2f523bd18c5034a46 529 Gene3D G3DSA:3.40.50.1380 1 202 7.9E-82 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily MIM_c10210 7ab7138ac6cbd5f2f523bd18c5034a46 529 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 4 529 1.3E-214 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MIM_c10210 7ab7138ac6cbd5f2f523bd18c5034a46 529 Pfam PF01808 AICARFT/IMPCHase bienzyme 135 459 3.4E-114 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MIM_c04040 e3a86d2a7f51ddd615df5055f677527d 155 Pfam PF08808 RES domain 3 138 3.8E-21 T 12-10-2018 IPR014914 RES domain MIM_c04040 e3a86d2a7f51ddd615df5055f677527d 155 SMART SM00953 14 138 1.3E-13 T 12-10-2018 IPR014914 RES domain MIM_c18740 8d2d2e901d42ba70650970cba25a316f 425 Pfam PF02687 FtsX-like permease family 311 418 1.4E-11 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MIM_c18740 8d2d2e901d42ba70650970cba25a316f 425 Pfam PF12704 MacB-like periplasmic core domain 37 253 1.1E-14 T 12-10-2018 IPR025857 MacB-like periplasmic core domain MIM_c18740 8d2d2e901d42ba70650970cba25a316f 425 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 4 424 4.2E-137 T 12-10-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 MIM_c01480 bac0fa6e2b848d5e66a84b90380be23a 322 Gene3D G3DSA:3.40.190.10 177 274 9.1E-62 T 12-10-2018 MIM_c01480 bac0fa6e2b848d5e66a84b90380be23a 322 Pfam PF03466 LysR substrate binding domain 101 301 1.1E-20 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c01480 bac0fa6e2b848d5e66a84b90380be23a 322 Gene3D G3DSA:3.40.190.10 96 299 9.1E-62 T 12-10-2018 MIM_c01480 bac0fa6e2b848d5e66a84b90380be23a 322 SUPERFAMILY SSF53850 96 301 5.79E-37 T 12-10-2018 MIM_c01480 bac0fa6e2b848d5e66a84b90380be23a 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 38 8.0E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c01480 bac0fa6e2b848d5e66a84b90380be23a 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 48 8.0E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c01480 bac0fa6e2b848d5e66a84b90380be23a 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 48 59 8.0E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c01480 bac0fa6e2b848d5e66a84b90380be23a 322 SUPERFAMILY SSF46785 10 91 5.37E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c01480 bac0fa6e2b848d5e66a84b90380be23a 322 Gene3D G3DSA:1.10.10.10 3 95 1.1E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c01480 bac0fa6e2b848d5e66a84b90380be23a 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 70 4.2E-13 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c36520 5f519b95db53fcd26d4e9ced30dc7ac4 568 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 82 105 - T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c36520 5f519b95db53fcd26d4e9ced30dc7ac4 568 PIRSF PIRSF000137 3 540 1.5E-156 T 12-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c36520 5f519b95db53fcd26d4e9ced30dc7ac4 568 Gene3D G3DSA:1.10.1220.110 97 150 6.9E-185 T 12-10-2018 MIM_c36520 5f519b95db53fcd26d4e9ced30dc7ac4 568 Gene3D G3DSA:3.30.410.40 151 471 6.9E-185 T 12-10-2018 MIM_c36520 5f519b95db53fcd26d4e9ced30dc7ac4 568 SUPERFAMILY SSF51905 4 534 3.56E-89 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c36520 5f519b95db53fcd26d4e9ced30dc7ac4 568 Pfam PF00732 GMC oxidoreductase 5 295 2.0E-91 T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c36520 5f519b95db53fcd26d4e9ced30dc7ac4 568 Gene3D G3DSA:4.10.450.10 38 196 6.9E-185 T 12-10-2018 IPR027424 Glucose Oxidase, domain 2 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 MIM_c36520 5f519b95db53fcd26d4e9ced30dc7ac4 568 Gene3D G3DSA:3.50.50.60 5 530 6.9E-185 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c36520 5f519b95db53fcd26d4e9ced30dc7ac4 568 Pfam PF05199 GMC oxidoreductase 388 526 9.0E-40 T 12-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 MIM_c36520 5f519b95db53fcd26d4e9ced30dc7ac4 568 SUPERFAMILY SSF54373 290 474 2.85E-58 T 12-10-2018 MIM_c36520 5f519b95db53fcd26d4e9ced30dc7ac4 568 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 254 268 - T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c19750 3065a2f35ba76d37c12b40d9697bc193 324 Gene3D G3DSA:3.40.190.150 26 311 1.6E-82 T 12-10-2018 MIM_c19750 3065a2f35ba76d37c12b40d9697bc193 324 SUPERFAMILY SSF53850 99 282 7.06E-10 T 12-10-2018 MIM_c19750 3065a2f35ba76d37c12b40d9697bc193 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 311 7.7E-51 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c19750 3065a2f35ba76d37c12b40d9697bc193 324 Gene3D G3DSA:3.40.190.10 124 247 1.6E-82 T 12-10-2018 MIM_c19750 3065a2f35ba76d37c12b40d9697bc193 324 PIRSF PIRSF017082 1 322 4.1E-95 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c11340 2bb639f4685ff5e8b95f6efc15d57b47 182 SUPERFAMILY SSF52172 10 123 1.29E-27 T 12-10-2018 IPR011006 CheY-like superfamily MIM_c11340 2bb639f4685ff5e8b95f6efc15d57b47 182 SUPERFAMILY SSF46689 130 179 1.46E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c11340 2bb639f4685ff5e8b95f6efc15d57b47 182 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 145 162 5.3E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MIM_c11340 2bb639f4685ff5e8b95f6efc15d57b47 182 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 162 182 5.3E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MIM_c11340 2bb639f4685ff5e8b95f6efc15d57b47 182 Gene3D G3DSA:1.10.10.60 125 180 2.7E-19 T 12-10-2018 MIM_c11340 2bb639f4685ff5e8b95f6efc15d57b47 182 Gene3D G3DSA:3.40.50.2300 10 124 1.6E-26 T 12-10-2018 MIM_c11340 2bb639f4685ff5e8b95f6efc15d57b47 182 Pfam PF02954 Bacterial regulatory protein, Fis family 140 178 3.5E-12 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MIM_c11340 2bb639f4685ff5e8b95f6efc15d57b47 182 Pfam PF00072 Response regulator receiver domain 12 120 5.0E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c11340 2bb639f4685ff5e8b95f6efc15d57b47 182 SMART SM00448 9 121 2.9E-20 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c29870 c12af7b782df09f20ce53cabee5317d4 264 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 9 253 1.2E-82 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 MIM_c29870 c12af7b782df09f20ce53cabee5317d4 264 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 138 150 - T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 MIM_c29870 c12af7b782df09f20ce53cabee5317d4 264 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 6 258 20.073 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 MIM_c29870 c12af7b782df09f20ce53cabee5317d4 264 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 2 258 9.4E-80 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 MIM_c11870 3c3193292cd6196ea925d0383ac99ab2 572 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 167 4.9E-59 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MIM_c11870 3c3193292cd6196ea925d0383ac99ab2 572 Gene3D G3DSA:3.40.50.970 365 571 1.0E-61 T 12-10-2018 MIM_c11870 3c3193292cd6196ea925d0383ac99ab2 572 SUPERFAMILY SSF52518 2 177 7.99E-65 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c11870 3c3193292cd6196ea925d0383ac99ab2 572 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 394 543 1.7E-46 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MIM_c11870 3c3193292cd6196ea925d0383ac99ab2 572 SUPERFAMILY SSF52518 372 567 3.32E-64 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c11870 3c3193292cd6196ea925d0383ac99ab2 572 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 194 329 5.8E-46 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MIM_c11870 3c3193292cd6196ea925d0383ac99ab2 572 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 3 566 1.2E-246 T 12-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MIM_c11870 3c3193292cd6196ea925d0383ac99ab2 572 Gene3D G3DSA:3.40.50.1220 188 360 5.7E-62 T 12-10-2018 MIM_c11870 3c3193292cd6196ea925d0383ac99ab2 572 Gene3D G3DSA:3.40.50.970 1 180 1.1E-71 T 12-10-2018 MIM_c11870 3c3193292cd6196ea925d0383ac99ab2 572 SUPERFAMILY SSF52467 186 362 3.82E-63 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MIM_c18550 5eae6244f9c67a324b0d36f760d84f37 107 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 12-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 MIM_c18550 5eae6244f9c67a324b0d36f760d84f37 107 SUPERFAMILY SSF89360 1 96 1.7E-32 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 MIM_c18550 5eae6244f9c67a324b0d36f760d84f37 107 TIGRFAM TIGR02011 IscA: iron-sulfur cluster assembly protein IscA 3 107 2.6E-52 T 12-10-2018 IPR011302 Iron-binding protein IscA, proteobacteria GO:0005506|GO:0051536|GO:0097428 MIM_c18550 5eae6244f9c67a324b0d36f760d84f37 107 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 103 4.1E-25 T 12-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MIM_c18550 5eae6244f9c67a324b0d36f760d84f37 107 Gene3D G3DSA:2.60.300.12 2 107 8.6E-39 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 MIM_c18550 5eae6244f9c67a324b0d36f760d84f37 107 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 3 107 3.1E-37 T 12-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 MIM_c20940 a90392f1eb4c5a1cfb9b477adcd71c28 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.2E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c20940 a90392f1eb4c5a1cfb9b477adcd71c28 313 Gene3D G3DSA:1.10.10.10 1 85 1.3E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c20940 a90392f1eb4c5a1cfb9b477adcd71c28 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.2E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c20940 a90392f1eb4c5a1cfb9b477adcd71c28 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.2E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c20940 a90392f1eb4c5a1cfb9b477adcd71c28 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.2E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c20940 a90392f1eb4c5a1cfb9b477adcd71c28 313 Pfam PF03466 LysR substrate binding domain 87 306 7.4E-28 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c20940 a90392f1eb4c5a1cfb9b477adcd71c28 313 SUPERFAMILY SSF53850 87 311 3.18E-29 T 12-10-2018 MIM_c20940 a90392f1eb4c5a1cfb9b477adcd71c28 313 Gene3D G3DSA:3.40.190.10 180 284 3.1E-40 T 12-10-2018 MIM_c20940 a90392f1eb4c5a1cfb9b477adcd71c28 313 Gene3D G3DSA:3.40.190.10 93 304 3.1E-40 T 12-10-2018 MIM_c20940 a90392f1eb4c5a1cfb9b477adcd71c28 313 SUPERFAMILY SSF46785 1 87 3.96E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c11520 191a8953499ff8167305cc484ba88d8a 333 Pfam PF01628 HrcA protein C terminal domain 101 316 2.1E-55 T 12-10-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 MIM_c11520 191a8953499ff8167305cc484ba88d8a 333 SUPERFAMILY SSF46785 1 76 2.55E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c11520 191a8953499ff8167305cc484ba88d8a 333 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 2 329 1.9E-93 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 MIM_c11520 191a8953499ff8167305cc484ba88d8a 333 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 6 69 4.4E-7 T 12-10-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 MIM_c11520 191a8953499ff8167305cc484ba88d8a 333 Gene3D G3DSA:3.30.390.60 123 220 2.5E-36 T 12-10-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain superfamily MIM_c11520 191a8953499ff8167305cc484ba88d8a 333 SUPERFAMILY SSF55781 68 331 5.1E-58 T 12-10-2018 MIM_c11520 191a8953499ff8167305cc484ba88d8a 333 Gene3D G3DSA:1.10.10.10 1 80 1.8E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c11520 191a8953499ff8167305cc484ba88d8a 333 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 323 26.004 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 MIM_c11520 191a8953499ff8167305cc484ba88d8a 333 PIRSF PIRSF005485 1 333 1.2E-104 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 MIM_c11520 191a8953499ff8167305cc484ba88d8a 333 Gene3D G3DSA:3.30.450.40 102 329 2.5E-36 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c26600 f180acb8f10a456b830955714c8b80bb 300 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 4 286 1.6E-149 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MIM_c26600 f180acb8f10a456b830955714c8b80bb 300 Gene3D G3DSA:3.30.930.10 1 210 4.9E-110 T 12-10-2018 MIM_c26600 f180acb8f10a456b830955714c8b80bb 300 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 77 97 3.1E-65 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MIM_c26600 f180acb8f10a456b830955714c8b80bb 300 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 134 154 3.1E-65 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MIM_c26600 f180acb8f10a456b830955714c8b80bb 300 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 108 132 3.1E-65 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MIM_c26600 f180acb8f10a456b830955714c8b80bb 300 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 157 172 3.1E-65 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MIM_c26600 f180acb8f10a456b830955714c8b80bb 300 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 247 263 3.1E-65 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MIM_c26600 f180acb8f10a456b830955714c8b80bb 300 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 56 71 3.1E-65 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MIM_c26600 f180acb8f10a456b830955714c8b80bb 300 SUPERFAMILY SSF55681 3 286 2.49E-131 T 12-10-2018 MIM_c26600 f180acb8f10a456b830955714c8b80bb 300 Gene3D G3DSA:1.20.58.180 211 292 4.3E-36 T 12-10-2018 MIM_c26600 f180acb8f10a456b830955714c8b80bb 300 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 3 294 7.2E-158 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MIM_c26600 f180acb8f10a456b830955714c8b80bb 300 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 2 287 60.276 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MIM_c35160 966b777b15c10941d8859fb0428aa176 350 Gene3D G3DSA:3.40.50.720 1 176 4.2E-31 T 12-10-2018 MIM_c35160 966b777b15c10941d8859fb0428aa176 350 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 180 320 1.0E-29 T 12-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain MIM_c35160 966b777b15c10941d8859fb0428aa176 350 SUPERFAMILY SSF51735 1 138 1.89E-12 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c35160 966b777b15c10941d8859fb0428aa176 350 SUPERFAMILY SSF48179 180 320 1.43E-28 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c35160 966b777b15c10941d8859fb0428aa176 350 Gene3D G3DSA:1.10.1040.10 181 325 2.3E-33 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MIM_c35160 966b777b15c10941d8859fb0428aa176 350 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 140 6.4E-23 T 12-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain MIM_c35160 966b777b15c10941d8859fb0428aa176 350 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 321 2.0E-50 T 12-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 MIM_c14810 125652afec5998792cc8319b4074ab11 621 Pfam PF02780 Transketolase, C-terminal domain 491 607 2.7E-26 T 12-10-2018 IPR033248 Transketolase, C-terminal domain MIM_c14810 125652afec5998792cc8319b4074ab11 621 Gene3D G3DSA:3.40.50.970 313 486 5.6E-65 T 12-10-2018 MIM_c14810 125652afec5998792cc8319b4074ab11 621 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 7 613 8.4E-258 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MIM_c14810 125652afec5998792cc8319b4074ab11 621 SMART SM00861 315 479 1.4E-62 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MIM_c14810 125652afec5998792cc8319b4074ab11 621 SUPERFAMILY SSF52922 487 615 3.14E-32 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MIM_c14810 125652afec5998792cc8319b4074ab11 621 Gene3D G3DSA:3.40.50.920 491 616 4.1E-42 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MIM_c14810 125652afec5998792cc8319b4074ab11 621 SUPERFAMILY SSF52518 1 345 1.34E-71 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c14810 125652afec5998792cc8319b4074ab11 621 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 4 616 44.982 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MIM_c14810 125652afec5998792cc8319b4074ab11 621 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 5 278 4.3E-115 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MIM_c14810 125652afec5998792cc8319b4074ab11 621 SUPERFAMILY SSF52518 290 475 5.03E-58 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c14810 125652afec5998792cc8319b4074ab11 621 ProSitePatterns PS00801 Transketolase signature 1. 30 49 - T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MIM_c14810 125652afec5998792cc8319b4074ab11 621 ProSitePatterns PS00802 Transketolase signature 2. 421 437 - T 12-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MIM_c14810 125652afec5998792cc8319b4074ab11 621 Pfam PF02779 Transketolase, pyrimidine binding domain 316 474 1.9E-37 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MIM_c00260 cdb91be29bedbed236800bdfa545ec89 452 PIRSF PIRSF000337 2 445 1.9E-154 T 12-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MIM_c00260 cdb91be29bedbed236800bdfa545ec89 452 Pfam PF00296 Luciferase-like monooxygenase 21 386 8.5E-59 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MIM_c00260 cdb91be29bedbed236800bdfa545ec89 452 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 8 430 5.5E-162 T 12-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MIM_c00260 cdb91be29bedbed236800bdfa545ec89 452 SUPERFAMILY SSF51679 3 434 1.02E-123 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MIM_c00260 cdb91be29bedbed236800bdfa545ec89 452 Gene3D G3DSA:3.20.20.30 1 450 6.0E-151 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MIM_c19740 b622c4dc53c797ef7834c42a29357c82 328 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 205 227 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MIM_c19740 b622c4dc53c797ef7834c42a29357c82 328 SUPERFAMILY SSF51735 113 296 2.6E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c19740 b622c4dc53c797ef7834c42a29357c82 328 SUPERFAMILY SSF52283 14 137 3.61E-21 T 12-10-2018 MIM_c19740 b622c4dc53c797ef7834c42a29357c82 328 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 119 295 4.4E-61 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MIM_c19740 b622c4dc53c797ef7834c42a29357c82 328 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 26 326 7.6E-22 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 MIM_c19740 b622c4dc53c797ef7834c42a29357c82 328 Gene3D G3DSA:3.40.50.720 27 318 8.5E-94 T 12-10-2018 MIM_c19740 b622c4dc53c797ef7834c42a29357c82 328 Gene3D G3DSA:3.40.50.720 110 293 8.5E-94 T 12-10-2018 MIM_c39390 59a8798e70f7df6b953a8d6d0ef61618 331 SUPERFAMILY SSF89733 2 328 4.58E-103 T 12-10-2018 IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily GO:0016491|GO:0055114 MIM_c39390 59a8798e70f7df6b953a8d6d0ef61618 331 Pfam PF02615 Malate/L-lactate dehydrogenase 5 328 8.3E-108 T 12-10-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0016491|GO:0055114 MIM_c39390 59a8798e70f7df6b953a8d6d0ef61618 331 Gene3D G3DSA:1.10.1530.10 12 327 3.7E-105 T 12-10-2018 MIM_c39390 59a8798e70f7df6b953a8d6d0ef61618 331 Gene3D G3DSA:3.30.1370.60 62 301 3.7E-105 T 12-10-2018 MIM_c39390 59a8798e70f7df6b953a8d6d0ef61618 331 Gene3D G3DSA:3.30.60.50 178 225 3.7E-105 T 12-10-2018 MIM_c13960 d4ac42da26fefe13dbbae8430e9f5965 322 PIRSF PIRSF017082 1 322 1.8E-60 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c13960 d4ac42da26fefe13dbbae8430e9f5965 322 Gene3D G3DSA:3.40.190.10 126 247 2.3E-87 T 12-10-2018 MIM_c13960 d4ac42da26fefe13dbbae8430e9f5965 322 Gene3D G3DSA:3.40.190.150 29 312 2.3E-87 T 12-10-2018 MIM_c13960 d4ac42da26fefe13dbbae8430e9f5965 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 318 2.2E-61 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c13960 d4ac42da26fefe13dbbae8430e9f5965 322 SUPERFAMILY SSF53850 114 284 4.35E-10 T 12-10-2018 MIM_c07610 6508f3b4c5c6a942a2121c748211a2a2 683 SMART SM00490 440 537 6.7E-6 T 12-10-2018 IPR001650 Helicase, C-terminal MIM_c07610 6508f3b4c5c6a942a2121c748211a2a2 683 Pfam PF04851 Type III restriction enzyme, res subunit 139 304 4.6E-12 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MIM_c07610 6508f3b4c5c6a942a2121c748211a2a2 683 SUPERFAMILY SSF52540 136 317 3.43E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c07610 6508f3b4c5c6a942a2121c748211a2a2 683 Gene3D G3DSA:3.40.50.300 128 324 5.1E-71 T 12-10-2018 MIM_c07610 6508f3b4c5c6a942a2121c748211a2a2 683 SUPERFAMILY SSF52540 407 559 1.05E-19 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c07610 6508f3b4c5c6a942a2121c748211a2a2 683 Gene3D G3DSA:1.10.8.630 4 109 4.7E-27 T 12-10-2018 MIM_c07610 6508f3b4c5c6a942a2121c748211a2a2 683 Hamap MF_00983 Probable primosomal protein N' [priA]. 8 683 23.391 T 12-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 MIM_c07610 6508f3b4c5c6a942a2121c748211a2a2 683 TIGRFAM TIGR00595 priA: primosomal protein N' 161 681 4.4E-168 T 12-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 MIM_c07610 6508f3b4c5c6a942a2121c748211a2a2 683 Pfam PF00271 Helicase conserved C-terminal domain 461 536 8.8E-5 T 12-10-2018 IPR001650 Helicase, C-terminal MIM_c07610 6508f3b4c5c6a942a2121c748211a2a2 683 SMART SM00487 136 337 3.7E-15 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MIM_c32970 614252c875f91e3d801fc462563a99dc 187 Hamap MF_00146 dCTP deaminase [dcd]. 1 187 27.105 T 12-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 MIM_c32970 614252c875f91e3d801fc462563a99dc 187 Gene3D G3DSA:2.70.40.10 1 158 6.1E-50 T 12-10-2018 IPR036157 dUTPase-like superfamily MIM_c32970 614252c875f91e3d801fc462563a99dc 187 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 17 186 6.5E-47 T 12-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 MIM_c32970 614252c875f91e3d801fc462563a99dc 187 SUPERFAMILY SSF51283 3 186 2.22E-51 T 12-10-2018 IPR036157 dUTPase-like superfamily MIM_c32970 614252c875f91e3d801fc462563a99dc 187 Pfam PF00692 dUTPase 81 183 1.5E-6 T 12-10-2018 IPR029054 dUTPase-like MIM_c36600 d846812695f62c78735c81b95a3c3801 326 SMART SM00382 61 207 0.0053 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c36600 d846812695f62c78735c81b95a3c3801 326 Pfam PF12556 Cobaltochelatase CobS subunit N terminal 12 38 7.6E-12 T 12-10-2018 IPR025865 Cobaltochelatase subunit CobS N-terminal domain KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 MIM_c36600 d846812695f62c78735c81b95a3c3801 326 Pfam PF07728 AAA domain (dynein-related subfamily) 65 192 1.8E-11 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 MIM_c36600 d846812695f62c78735c81b95a3c3801 326 Gene3D G3DSA:3.40.50.300 48 227 4.3E-24 T 12-10-2018 MIM_c36600 d846812695f62c78735c81b95a3c3801 326 SUPERFAMILY SSF52540 39 313 3.77E-31 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c04500 329389fe88d92afe26486f01ddc9afc8 458 SUPERFAMILY SSF51161 256 437 7.26E-48 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily MIM_c04500 329389fe88d92afe26486f01ddc9afc8 458 Gene3D G3DSA:2.160.10.10 229 457 1.3E-62 T 12-10-2018 MIM_c04500 329389fe88d92afe26486f01ddc9afc8 458 Pfam PF12804 MobA-like NTP transferase domain 5 126 3.5E-22 T 12-10-2018 IPR025877 MobA-like NTP transferase MIM_c04500 329389fe88d92afe26486f01ddc9afc8 458 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 3 456 4.2E-191 T 12-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 MIM_c04500 329389fe88d92afe26486f01ddc9afc8 458 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 269 301 2.8E-4 T 12-10-2018 IPR001451 Hexapeptide repeat MIM_c04500 329389fe88d92afe26486f01ddc9afc8 458 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 396 430 1.9E-6 T 12-10-2018 IPR001451 Hexapeptide repeat MIM_c04500 329389fe88d92afe26486f01ddc9afc8 458 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 1 453 42.428 T 12-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 MIM_c04500 329389fe88d92afe26486f01ddc9afc8 458 Gene3D G3DSA:3.90.550.10 1 228 5.3E-63 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MIM_c04500 329389fe88d92afe26486f01ddc9afc8 458 SUPERFAMILY SSF53448 2 253 2.48E-60 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MIM_c13840 8044c6f3c4ef6fe9f6c85796f8c32fc4 401 Gene3D G3DSA:3.40.50.10540 9 395 1.3E-123 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c13840 8044c6f3c4ef6fe9f6c85796f8c32fc4 401 SUPERFAMILY SSF89796 8 401 3.27E-121 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c13840 8044c6f3c4ef6fe9f6c85796f8c32fc4 401 Gene3D G3DSA:3.30.1540.10 235 328 1.3E-123 T 12-10-2018 MIM_c13840 8044c6f3c4ef6fe9f6c85796f8c32fc4 401 Pfam PF02515 CoA-transferase family III 10 373 5.3E-114 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 MIM_c00550 cce27260598e81acc71c58f9321ade37 250 Gene3D G3DSA:1.20.120.530 107 249 9.0E-26 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c00550 cce27260598e81acc71c58f9321ade37 250 SUPERFAMILY SSF48008 109 245 1.83E-23 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c00550 cce27260598e81acc71c58f9321ade37 250 SMART SM00345 34 91 1.2E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c00550 cce27260598e81acc71c58f9321ade37 250 SMART SM00895 113 239 6.0E-18 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c00550 cce27260598e81acc71c58f9321ade37 250 Pfam PF07729 FCD domain 115 238 1.9E-21 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c00550 cce27260598e81acc71c58f9321ade37 250 SUPERFAMILY SSF46785 29 95 3.99E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c00550 cce27260598e81acc71c58f9321ade37 250 Pfam PF00392 Bacterial regulatory proteins, gntR family 35 90 4.7E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c00550 cce27260598e81acc71c58f9321ade37 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 65 4.9E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c00550 cce27260598e81acc71c58f9321ade37 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 65 81 4.9E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c00550 cce27260598e81acc71c58f9321ade37 250 Gene3D G3DSA:1.10.10.10 34 92 8.5E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c21050 185ae4f89c4291a1f613ce686860a3d2 492 Pfam PF02321 Outer membrane efflux protein 72 261 5.3E-25 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MIM_c21050 185ae4f89c4291a1f613ce686860a3d2 492 Pfam PF02321 Outer membrane efflux protein 290 475 6.5E-27 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MIM_c21050 185ae4f89c4291a1f613ce686860a3d2 492 SUPERFAMILY SSF56954 8 480 1.7E-102 T 12-10-2018 MIM_c21050 185ae4f89c4291a1f613ce686860a3d2 492 Gene3D G3DSA:1.20.1600.10 62 478 4.9E-128 T 12-10-2018 MIM_c21050 185ae4f89c4291a1f613ce686860a3d2 492 Gene3D G3DSA:2.20.200.10 108 365 4.9E-128 T 12-10-2018 MIM_c21050 185ae4f89c4291a1f613ce686860a3d2 492 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 17 477 3.5E-112 T 12-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 MIM_c20670 8a70d24273b281e08c96eb5a0bdae0a6 391 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 344 363 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MIM_c20670 8a70d24273b281e08c96eb5a0bdae0a6 391 Gene3D G3DSA:1.20.140.10 242 388 2.8E-50 T 12-10-2018 MIM_c20670 8a70d24273b281e08c96eb5a0bdae0a6 391 Gene3D G3DSA:1.10.540.10 2 125 4.0E-28 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c20670 8a70d24273b281e08c96eb5a0bdae0a6 391 SUPERFAMILY SSF47203 235 388 8.38E-51 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c20670 8a70d24273b281e08c96eb5a0bdae0a6 391 Gene3D G3DSA:2.40.110.10 128 241 2.5E-33 T 12-10-2018 MIM_c20670 8a70d24273b281e08c96eb5a0bdae0a6 391 PIRSF PIRSF016578 135 391 5.3E-9 T 12-10-2018 MIM_c20670 8a70d24273b281e08c96eb5a0bdae0a6 391 PIRSF PIRSF016578 12 113 5.6E-10 T 12-10-2018 MIM_c20670 8a70d24273b281e08c96eb5a0bdae0a6 391 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 124 1.4E-24 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c20670 8a70d24273b281e08c96eb5a0bdae0a6 391 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 224 6.9E-22 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MIM_c20670 8a70d24273b281e08c96eb5a0bdae0a6 391 SUPERFAMILY SSF56645 13 232 1.57E-61 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c20670 8a70d24273b281e08c96eb5a0bdae0a6 391 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 384 1.5E-44 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MIM_c29290 01968c644e956a5531365fd9940ae61d 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 1.5E-44 T 12-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 MIM_c29290 01968c644e956a5531365fd9940ae61d 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 12-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 MIM_c29290 01968c644e956a5531365fd9940ae61d 130 Gene3D G3DSA:3.30.230.10 2 130 3.7E-50 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MIM_c29290 01968c644e956a5531365fd9940ae61d 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 31.181 T 12-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid MIM_c29290 01968c644e956a5531365fd9940ae61d 130 SUPERFAMILY SSF54211 5 130 1.59E-46 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MIM_c20700 2920ecd85eaa5ebbf19ba649b8ccf1b9 568 Gene3D G3DSA:3.40.50.12780 3 443 1.7E-87 T 12-10-2018 MIM_c20700 2920ecd85eaa5ebbf19ba649b8ccf1b9 568 SUPERFAMILY SSF56801 24 545 2.75E-122 T 12-10-2018 MIM_c20700 2920ecd85eaa5ebbf19ba649b8ccf1b9 568 Gene3D G3DSA:3.30.300.310 444 547 9.3E-24 T 12-10-2018 MIM_c20700 2920ecd85eaa5ebbf19ba649b8ccf1b9 568 Pfam PF00501 AMP-binding enzyme 33 448 6.8E-81 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MIM_c20700 2920ecd85eaa5ebbf19ba649b8ccf1b9 568 ProSitePatterns PS00455 Putative AMP-binding domain signature. 200 211 - T 12-10-2018 IPR020845 AMP-binding, conserved site MIM_c20700 2920ecd85eaa5ebbf19ba649b8ccf1b9 568 Pfam PF13193 AMP-binding enzyme C-terminal domain 458 533 4.8E-6 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MIM_c14700 07dc7236cecbf97b9e5d2ad6c4ea196f 885 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 436 590 5.8E-8 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c14700 07dc7236cecbf97b9e5d2ad6c4ea196f 885 Pfam PF09334 tRNA synthetases class I (M) 44 177 4.4E-17 T 12-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c14700 07dc7236cecbf97b9e5d2ad6c4ea196f 885 Gene3D G3DSA:3.10.330.110 586 648 0.0 T 12-10-2018 MIM_c14700 07dc7236cecbf97b9e5d2ad6c4ea196f 885 Gene3D G3DSA:1.10.730.10 9 817 0.0 T 12-10-2018 MIM_c14700 07dc7236cecbf97b9e5d2ad6c4ea196f 885 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 6 884 0.0 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MIM_c14700 07dc7236cecbf97b9e5d2ad6c4ea196f 885 SUPERFAMILY SSF47323 683 884 2.43E-29 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c14700 07dc7236cecbf97b9e5d2ad6c4ea196f 885 Gene3D G3DSA:3.90.740.10 234 432 0.0 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MIM_c14700 07dc7236cecbf97b9e5d2ad6c4ea196f 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 133 150 9.3E-48 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MIM_c14700 07dc7236cecbf97b9e5d2ad6c4ea196f 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 191 204 9.3E-48 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MIM_c14700 07dc7236cecbf97b9e5d2ad6c4ea196f 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 159 175 9.3E-48 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MIM_c14700 07dc7236cecbf97b9e5d2ad6c4ea196f 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 576 586 9.3E-48 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MIM_c14700 07dc7236cecbf97b9e5d2ad6c4ea196f 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 222 241 9.3E-48 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MIM_c14700 07dc7236cecbf97b9e5d2ad6c4ea196f 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 543 565 9.3E-48 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MIM_c14700 07dc7236cecbf97b9e5d2ad6c4ea196f 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 505 523 9.3E-48 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MIM_c14700 07dc7236cecbf97b9e5d2ad6c4ea196f 885 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 228 420 4.9E-64 T 12-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 MIM_c14700 07dc7236cecbf97b9e5d2ad6c4ea196f 885 SUPERFAMILY SSF50677 237 432 1.47E-50 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MIM_c14700 07dc7236cecbf97b9e5d2ad6c4ea196f 885 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 48 59 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c14700 07dc7236cecbf97b9e5d2ad6c4ea196f 885 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 4 885 22.313 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MIM_c14700 07dc7236cecbf97b9e5d2ad6c4ea196f 885 Gene3D G3DSA:3.40.50.620 39 585 0.0 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c14700 07dc7236cecbf97b9e5d2ad6c4ea196f 885 Pfam PF08264 Anticodon-binding domain of tRNA 727 847 1.1E-14 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 MIM_c14700 07dc7236cecbf97b9e5d2ad6c4ea196f 885 Gene3D G3DSA:3.10.20.590 827 885 2.0E-18 T 12-10-2018 MIM_c14700 07dc7236cecbf97b9e5d2ad6c4ea196f 885 SUPERFAMILY SSF52374 4 686 1.2E-139 T 12-10-2018 MIM_c01980 6bfb18deb991ef0af0f3d026e5cc040c 378 Gene3D G3DSA:3.40.50.2300 146 274 7.1E-97 T 12-10-2018 MIM_c01980 6bfb18deb991ef0af0f3d026e5cc040c 378 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 256 274 1.2E-11 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MIM_c01980 6bfb18deb991ef0af0f3d026e5cc040c 378 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 49 65 1.2E-11 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MIM_c01980 6bfb18deb991ef0af0f3d026e5cc040c 378 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 27 43 1.2E-11 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MIM_c01980 6bfb18deb991ef0af0f3d026e5cc040c 378 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 68 86 1.2E-11 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MIM_c01980 6bfb18deb991ef0af0f3d026e5cc040c 378 Pfam PF13458 Periplasmic binding protein 26 365 5.8E-75 T 12-10-2018 IPR028081 Leucine-binding protein domain MIM_c01980 6bfb18deb991ef0af0f3d026e5cc040c 378 SUPERFAMILY SSF53822 25 370 3.24E-95 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c01980 6bfb18deb991ef0af0f3d026e5cc040c 378 Gene3D G3DSA:3.40.50.2300 29 343 7.1E-97 T 12-10-2018 MIM_c14670 75b7b8afb8d33ae18c62d35a83c06047 426 Gene3D G3DSA:3.40.309.10 235 383 9.5E-158 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MIM_c14670 75b7b8afb8d33ae18c62d35a83c06047 426 PIRSF PIRSF000151 9 426 2.3E-170 T 12-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 MIM_c14670 75b7b8afb8d33ae18c62d35a83c06047 426 Pfam PF00171 Aldehyde dehydrogenase family 20 290 1.6E-15 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c14670 75b7b8afb8d33ae18c62d35a83c06047 426 Pfam PF00171 Aldehyde dehydrogenase family 318 382 1.5E-5 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c14670 75b7b8afb8d33ae18c62d35a83c06047 426 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 22 415 8.4E-144 T 12-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MIM_c14670 75b7b8afb8d33ae18c62d35a83c06047 426 SUPERFAMILY SSF53720 17 425 5.5E-116 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c14670 75b7b8afb8d33ae18c62d35a83c06047 426 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 14 425 40.747 T 12-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MIM_c14670 75b7b8afb8d33ae18c62d35a83c06047 426 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 332 353 - T 12-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MIM_c14670 75b7b8afb8d33ae18c62d35a83c06047 426 Gene3D G3DSA:3.40.605.10 21 422 9.5E-158 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c12690 6c96226b2eac5621474dde71f7f9f945 332 Pfam PF00175 Oxidoreductase NAD-binding domain 124 212 1.9E-4 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MIM_c12690 6c96226b2eac5621474dde71f7f9f945 332 Gene3D G3DSA:2.40.30.10 10 112 5.8E-26 T 12-10-2018 MIM_c12690 6c96226b2eac5621474dde71f7f9f945 332 PRINTS PR00409 Phthalate dioxygenase reductase family signature 51 63 6.8E-43 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MIM_c12690 6c96226b2eac5621474dde71f7f9f945 332 PRINTS PR00409 Phthalate dioxygenase reductase family signature 41 51 6.8E-43 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MIM_c12690 6c96226b2eac5621474dde71f7f9f945 332 PRINTS PR00409 Phthalate dioxygenase reductase family signature 123 142 6.8E-43 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MIM_c12690 6c96226b2eac5621474dde71f7f9f945 332 PRINTS PR00409 Phthalate dioxygenase reductase family signature 199 207 6.8E-43 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MIM_c12690 6c96226b2eac5621474dde71f7f9f945 332 PRINTS PR00409 Phthalate dioxygenase reductase family signature 63 77 6.8E-43 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MIM_c12690 6c96226b2eac5621474dde71f7f9f945 332 PRINTS PR00409 Phthalate dioxygenase reductase family signature 87 101 6.8E-43 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MIM_c12690 6c96226b2eac5621474dde71f7f9f945 332 PRINTS PR00409 Phthalate dioxygenase reductase family signature 148 157 6.8E-43 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MIM_c12690 6c96226b2eac5621474dde71f7f9f945 332 PRINTS PR00409 Phthalate dioxygenase reductase family signature 101 115 6.8E-43 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MIM_c12690 6c96226b2eac5621474dde71f7f9f945 332 Gene3D G3DSA:3.10.20.30 238 332 1.9E-25 T 12-10-2018 IPR012675 Beta-grasp domain superfamily MIM_c12690 6c96226b2eac5621474dde71f7f9f945 332 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 253 323 1.6E-11 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MIM_c12690 6c96226b2eac5621474dde71f7f9f945 332 SUPERFAMILY SSF63380 14 111 8.96E-25 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MIM_c12690 6c96226b2eac5621474dde71f7f9f945 332 SUPERFAMILY SSF52343 109 235 9.43E-29 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MIM_c12690 6c96226b2eac5621474dde71f7f9f945 332 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 283 291 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MIM_c12690 6c96226b2eac5621474dde71f7f9f945 332 Gene3D G3DSA:3.40.50.80 113 229 1.1E-28 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MIM_c12690 6c96226b2eac5621474dde71f7f9f945 332 SUPERFAMILY SSF54292 219 331 8.13E-26 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MIM_c06380 88d180d4d71dde3ffc133b68289fc090 686 SMART SM00382 369 526 1.3E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c06380 88d180d4d71dde3ffc133b68289fc090 686 Gene3D G3DSA:1.10.10.60 630 672 1.6E-9 T 12-10-2018 MIM_c06380 88d180d4d71dde3ffc133b68289fc090 686 Gene3D G3DSA:3.40.50.300 335 533 5.4E-58 T 12-10-2018 MIM_c06380 88d180d4d71dde3ffc133b68289fc090 686 Gene3D G3DSA:3.30.450.40 30 217 9.0E-55 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c06380 88d180d4d71dde3ffc133b68289fc090 686 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 653 673 7.9E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MIM_c06380 88d180d4d71dde3ffc133b68289fc090 686 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 636 653 7.9E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MIM_c06380 88d180d4d71dde3ffc133b68289fc090 686 Gene3D G3DSA:1.10.8.60 534 614 4.8E-24 T 12-10-2018 MIM_c06380 88d180d4d71dde3ffc133b68289fc090 686 SUPERFAMILY SSF46689 576 672 2.78E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c06380 88d180d4d71dde3ffc133b68289fc090 686 Pfam PF00158 Sigma-54 interaction domain 349 529 4.7E-60 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MIM_c06380 88d180d4d71dde3ffc133b68289fc090 686 Pfam PF01590 GAF domain 80 213 4.4E-6 T 12-10-2018 IPR003018 GAF domain GO:0005515 MIM_c06380 88d180d4d71dde3ffc133b68289fc090 686 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 576 585 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site MIM_c06380 88d180d4d71dde3ffc133b68289fc090 686 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 449 464 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MIM_c06380 88d180d4d71dde3ffc133b68289fc090 686 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 373 386 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MIM_c06380 88d180d4d71dde3ffc133b68289fc090 686 Pfam PF02954 Bacterial regulatory protein, Fis family 633 670 1.1E-7 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MIM_c06380 88d180d4d71dde3ffc133b68289fc090 686 SUPERFAMILY SSF52540 349 606 4.03E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c02030 f6bb8fbfd7552ab5abf0b3f8f5f2fdf8 409 SUPERFAMILY SSF54373 177 278 5.89E-16 T 12-10-2018 MIM_c02030 f6bb8fbfd7552ab5abf0b3f8f5f2fdf8 409 SUPERFAMILY SSF51905 6 374 9.15E-66 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c02030 f6bb8fbfd7552ab5abf0b3f8f5f2fdf8 409 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 317 1.7E-20 T 12-10-2018 MIM_c02030 f6bb8fbfd7552ab5abf0b3f8f5f2fdf8 409 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 286 301 1.7E-20 T 12-10-2018 MIM_c02030 f6bb8fbfd7552ab5abf0b3f8f5f2fdf8 409 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 1.7E-20 T 12-10-2018 MIM_c02030 f6bb8fbfd7552ab5abf0b3f8f5f2fdf8 409 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.7E-20 T 12-10-2018 MIM_c02030 f6bb8fbfd7552ab5abf0b3f8f5f2fdf8 409 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 335 351 1.7E-20 T 12-10-2018 MIM_c02030 f6bb8fbfd7552ab5abf0b3f8f5f2fdf8 409 Pfam PF01494 FAD binding domain 5 346 5.2E-28 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 MIM_c02030 f6bb8fbfd7552ab5abf0b3f8f5f2fdf8 409 Gene3D G3DSA:3.50.50.60 6 381 7.9E-119 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c40550 2e7e773a2df25923747990868c9a93e7 360 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 30 320 1.2E-95 T 12-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 MIM_c40550 2e7e773a2df25923747990868c9a93e7 360 Gene3D G3DSA:3.30.1780.10 26 341 1.6E-123 T 12-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 MIM_c40550 2e7e773a2df25923747990868c9a93e7 360 SUPERFAMILY SSF51735 13 343 5.79E-88 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c40550 2e7e773a2df25923747990868c9a93e7 360 Gene3D G3DSA:3.40.50.720 135 303 1.6E-123 T 12-10-2018 MIM_c36760 f7d591f17ee843c916b47655b096d2ef 237 SUPERFAMILY SSF102588 4 234 8.5E-50 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 MIM_c36760 f7d591f17ee843c916b47655b096d2ef 237 Gene3D G3DSA:3.40.50.10320 3 237 1.7E-84 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 MIM_c36760 f7d591f17ee843c916b47655b096d2ef 237 Pfam PF02585 GlcNAc-PI de-N-acetylase 7 135 5.0E-21 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 MIM_c20770 e5dc5dceadb8f667b226b328ae8848df 287 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 275 8.6E-36 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c28360 e0c586579efb7dfd32e8e32ab7920fee 238 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 119 3.0E-13 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c28360 e0c586579efb7dfd32e8e32ab7920fee 238 Gene3D G3DSA:1.10.3720.10 6 227 1.4E-44 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c28360 e0c586579efb7dfd32e8e32ab7920fee 238 SUPERFAMILY SSF161098 16 215 3.14E-35 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c28360 e0c586579efb7dfd32e8e32ab7920fee 238 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 226 2.0E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c27060 1ea3989108d9ef5964818216fdac0307 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 31.22 T 12-10-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c27060 1ea3989108d9ef5964818216fdac0307 100 SUPERFAMILY SSF54111 1 99 8.5E-42 T 12-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c27060 1ea3989108d9ef5964818216fdac0307 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 100 3.9E-46 T 12-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c27060 1ea3989108d9ef5964818216fdac0307 100 Gene3D G3DSA:3.30.280.10 1 100 7.9E-43 T 12-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c27060 1ea3989108d9ef5964818216fdac0307 100 Pfam PF00547 Urease, gamma subunit 1 99 3.4E-42 T 12-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c27060 1ea3989108d9ef5964818216fdac0307 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 2.0E-34 T 12-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c27060 1ea3989108d9ef5964818216fdac0307 100 PIRSF PIRSF001223 1 100 2.8E-45 T 12-10-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c19890 39ffbca8b9e890939e2d814d8ce04a28 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 323 2.6E-84 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c19890 39ffbca8b9e890939e2d814d8ce04a28 326 PIRSF PIRSF017082 2 326 8.0E-81 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c19890 39ffbca8b9e890939e2d814d8ce04a28 326 Gene3D G3DSA:3.40.190.10 127 251 1.0E-108 T 12-10-2018 MIM_c19890 39ffbca8b9e890939e2d814d8ce04a28 326 SUPERFAMILY SSF53850 115 288 4.44E-13 T 12-10-2018 MIM_c19890 39ffbca8b9e890939e2d814d8ce04a28 326 Gene3D G3DSA:3.40.190.150 30 316 1.0E-108 T 12-10-2018 MIM_c03480 03bf25c4ec2d76f66a1c66b7e5485955 401 SUPERFAMILY SSF53383 56 396 4.35E-91 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c03480 03bf25c4ec2d76f66a1c66b7e5485955 401 Gene3D G3DSA:3.40.640.10 3 263 8.1E-70 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c03480 03bf25c4ec2d76f66a1c66b7e5485955 401 Gene3D G3DSA:3.90.1150.10 265 400 4.7E-37 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c03480 03bf25c4ec2d76f66a1c66b7e5485955 401 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 206 220 - T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MIM_c03480 03bf25c4ec2d76f66a1c66b7e5485955 401 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 30 396 2.7E-103 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MIM_c03480 03bf25c4ec2d76f66a1c66b7e5485955 401 PIRSF PIRSF001434 1 399 1.0E-117 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MIM_c34580 a9af0a01316e015f90036955c6dbe7dd 359 Gene3D G3DSA:3.40.50.300 3 246 2.4E-70 T 12-10-2018 MIM_c34580 a9af0a01316e015f90036955c6dbe7dd 359 SMART SM00382 37 220 1.0E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c34580 a9af0a01316e015f90036955c6dbe7dd 359 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c34580 a9af0a01316e015f90036955c6dbe7dd 359 Pfam PF00005 ABC transporter 28 170 2.3E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c34580 a9af0a01316e015f90036955c6dbe7dd 359 SUPERFAMILY SSF52540 9 251 3.96E-82 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c34580 a9af0a01316e015f90036955c6dbe7dd 359 Gene3D G3DSA:2.40.50.100 285 355 1.3E-5 T 12-10-2018 MIM_c34580 a9af0a01316e015f90036955c6dbe7dd 359 SUPERFAMILY SSF50331 258 356 1.51E-12 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MIM_c34580 a9af0a01316e015f90036955c6dbe7dd 359 Gene3D G3DSA:2.40.50.140 288 347 1.3E-5 T 12-10-2018 MIM_c34580 a9af0a01316e015f90036955c6dbe7dd 359 Pfam PF08402 TOBE domain 285 353 6.2E-8 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 MIM_c08450 38c4088ad9de1fc7b39899ea6d601a01 407 Gene3D G3DSA:3.40.640.10 71 293 2.0E-127 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c08450 38c4088ad9de1fc7b39899ea6d601a01 407 Gene3D G3DSA:3.90.1150.10 34 399 2.0E-127 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c08450 38c4088ad9de1fc7b39899ea6d601a01 407 SUPERFAMILY SSF53383 12 404 2.18E-105 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c08450 38c4088ad9de1fc7b39899ea6d601a01 407 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 243 256 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 MIM_c08450 38c4088ad9de1fc7b39899ea6d601a01 407 Pfam PF00155 Aminotransferase class I and II 40 399 2.2E-72 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MIM_c09940 06a1b2344e171cbe6d22d543ccd4b068 477 Pfam PF00171 Aldehyde dehydrogenase family 17 472 2.1E-153 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c09940 06a1b2344e171cbe6d22d543ccd4b068 477 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 245 252 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MIM_c09940 06a1b2344e171cbe6d22d543ccd4b068 477 Gene3D G3DSA:3.40.309.10 249 441 7.7E-162 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MIM_c09940 06a1b2344e171cbe6d22d543ccd4b068 477 Gene3D G3DSA:3.40.605.10 20 466 7.7E-162 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c09940 06a1b2344e171cbe6d22d543ccd4b068 477 SUPERFAMILY SSF53720 3 473 1.57E-149 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c09940 06a1b2344e171cbe6d22d543ccd4b068 477 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 273 284 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MIM_c24210 fbda65a8835737313bd15bbd2cecf80f 616 Pfam PF02653 Branched-chain amino acid transport system / permease component 28 297 5.1E-34 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c24210 fbda65a8835737313bd15bbd2cecf80f 616 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 572 593 3.1E-9 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal MIM_c24210 fbda65a8835737313bd15bbd2cecf80f 616 SUPERFAMILY SSF52540 347 592 5.74E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c24210 fbda65a8835737313bd15bbd2cecf80f 616 SMART SM00382 373 571 6.8E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c24210 fbda65a8835737313bd15bbd2cecf80f 616 Gene3D G3DSA:3.40.50.300 344 594 1.9E-59 T 12-10-2018 MIM_c24210 fbda65a8835737313bd15bbd2cecf80f 616 Pfam PF00005 ABC transporter 365 522 8.2E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c21840 e1f15b6843dab20f4e1170991a0262c4 65 Pfam PF01632 Ribosomal protein L35 2 62 1.4E-24 T 12-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c21840 e1f15b6843dab20f4e1170991a0262c4 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.543 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MIM_c21840 e1f15b6843dab20f4e1170991a0262c4 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 12-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c21840 e1f15b6843dab20f4e1170991a0262c4 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 8.5E-19 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MIM_c21840 e1f15b6843dab20f4e1170991a0262c4 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 8.5E-19 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MIM_c21840 e1f15b6843dab20f4e1170991a0262c4 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 8.5E-19 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MIM_c21840 e1f15b6843dab20f4e1170991a0262c4 65 SUPERFAMILY SSF143034 2 64 2.75E-23 T 12-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c21840 e1f15b6843dab20f4e1170991a0262c4 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 1.1E-26 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MIM_c21840 e1f15b6843dab20f4e1170991a0262c4 65 Gene3D G3DSA:2.40.50.530 1 65 3.5E-21 T 12-10-2018 MIM_c29190 4aeba290c57b1fa679e105268f565740 201 Gene3D G3DSA:2.40.30.20 1 91 8.9E-21 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MIM_c29190 4aeba290c57b1fa679e105268f565740 201 Gene3D G3DSA:2.40.30.20 104 201 6.5E-35 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MIM_c29190 4aeba290c57b1fa679e105268f565740 201 SUPERFAMILY SSF63380 1 94 1.11E-17 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MIM_c29190 4aeba290c57b1fa679e105268f565740 201 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 201 2.8E-54 T 12-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MIM_c29190 4aeba290c57b1fa679e105268f565740 201 Pfam PF00677 Lumazine binding domain 3 88 5.6E-16 T 12-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MIM_c29190 4aeba290c57b1fa679e105268f565740 201 Pfam PF00677 Lumazine binding domain 102 190 4.2E-25 T 12-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MIM_c29190 4aeba290c57b1fa679e105268f565740 201 SUPERFAMILY SSF63380 96 200 9.35E-32 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MIM_c29190 4aeba290c57b1fa679e105268f565740 201 PIRSF PIRSF000498 1 201 6.1E-67 T 12-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MIM_c23830 271f9110f87cd32eb6139df4e8ba52eb 597 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site MIM_c23830 271f9110f87cd32eb6139df4e8ba52eb 597 SUPERFAMILY SSF50447 165 288 3.12E-28 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MIM_c23830 271f9110f87cd32eb6139df4e8ba52eb 597 Gene3D G3DSA:3.30.70.2570 479 553 1.3E-32 T 12-10-2018 IPR038363 LepA, C-terminal domain superfamily MIM_c23830 271f9110f87cd32eb6139df4e8ba52eb 597 Pfam PF00009 Elongation factor Tu GTP binding domain 3 181 6.5E-54 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c23830 271f9110f87cd32eb6139df4e8ba52eb 597 Hamap MF_00071 Elongation factor 4 [lepA]. 1 597 300.497 T 12-10-2018 IPR006297 Elongation factor 4 GO:0005525 MIM_c23830 271f9110f87cd32eb6139df4e8ba52eb 597 PRINTS PR00315 GTP-binding elongation factor signature 6 19 3.2E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c23830 271f9110f87cd32eb6139df4e8ba52eb 597 PRINTS PR00315 GTP-binding elongation factor signature 90 101 3.2E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c23830 271f9110f87cd32eb6139df4e8ba52eb 597 PRINTS PR00315 GTP-binding elongation factor signature 74 84 3.2E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c23830 271f9110f87cd32eb6139df4e8ba52eb 597 PRINTS PR00315 GTP-binding elongation factor signature 49 57 3.2E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c23830 271f9110f87cd32eb6139df4e8ba52eb 597 PRINTS PR00315 GTP-binding elongation factor signature 126 135 3.2E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MIM_c23830 271f9110f87cd32eb6139df4e8ba52eb 597 Gene3D G3DSA:3.40.50.300 1 185 1.4E-72 T 12-10-2018 MIM_c23830 271f9110f87cd32eb6139df4e8ba52eb 597 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 176 1.1E-19 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MIM_c23830 271f9110f87cd32eb6139df4e8ba52eb 597 Pfam PF03144 Elongation factor Tu domain 2 205 275 2.1E-8 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MIM_c23830 271f9110f87cd32eb6139df4e8ba52eb 597 SUPERFAMILY SSF54980 399 493 1.01E-25 T 12-10-2018 IPR035647 EF-G domain III/V-like MIM_c23830 271f9110f87cd32eb6139df4e8ba52eb 597 Gene3D G3DSA:2.40.30.10 186 285 1.0E-31 T 12-10-2018 MIM_c23830 271f9110f87cd32eb6139df4e8ba52eb 597 SMART SM00838 398 486 0.0062 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like MIM_c23830 271f9110f87cd32eb6139df4e8ba52eb 597 Gene3D G3DSA:3.30.70.3380 368 478 7.3E-42 T 12-10-2018 MIM_c23830 271f9110f87cd32eb6139df4e8ba52eb 597 TIGRFAM TIGR01393 lepA: elongation factor 4 3 595 5.0E-295 T 12-10-2018 IPR006297 Elongation factor 4 GO:0005525 MIM_c23830 271f9110f87cd32eb6139df4e8ba52eb 597 Gene3D G3DSA:3.30.70.870 286 367 1.6E-35 T 12-10-2018 MIM_c23830 271f9110f87cd32eb6139df4e8ba52eb 597 Pfam PF00679 Elongation factor G C-terminus 399 479 1.2E-21 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like MIM_c23830 271f9110f87cd32eb6139df4e8ba52eb 597 SUPERFAMILY SSF54980 292 370 8.99E-19 T 12-10-2018 IPR035647 EF-G domain III/V-like MIM_c23830 271f9110f87cd32eb6139df4e8ba52eb 597 Pfam PF06421 GTP-binding protein LepA C-terminus 487 593 1.4E-49 T 12-10-2018 IPR013842 GTP-binding protein LepA, C-terminal MIM_c23830 271f9110f87cd32eb6139df4e8ba52eb 597 SUPERFAMILY SSF52540 2 205 3.58E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c01070 a39326ff83d4febeec01b464b7f20151 448 SUPERFAMILY SSF51905 22 438 1.42E-53 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c01070 a39326ff83d4febeec01b464b7f20151 448 Gene3D G3DSA:3.30.9.10 102 327 1.9E-57 T 12-10-2018 MIM_c01070 a39326ff83d4febeec01b464b7f20151 448 Gene3D G3DSA:3.30.9.10 340 378 9.3E-21 T 12-10-2018 MIM_c01070 a39326ff83d4febeec01b464b7f20151 448 Gene3D G3DSA:3.50.50.60 379 420 9.3E-21 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c01070 a39326ff83d4febeec01b464b7f20151 448 Pfam PF01266 FAD dependent oxidoreductase 23 418 2.1E-68 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MIM_c01070 a39326ff83d4febeec01b464b7f20151 448 Gene3D G3DSA:3.50.50.60 23 238 1.9E-57 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c21420 71b5a7ffc3628bfc6dcbb0f34bdbb085 280 Gene3D G3DSA:3.40.50.150 60 279 4.5E-66 T 12-10-2018 MIM_c21420 71b5a7ffc3628bfc6dcbb0f34bdbb085 280 SUPERFAMILY SSF53335 81 277 8.29E-38 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c21420 71b5a7ffc3628bfc6dcbb0f34bdbb085 280 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 78 275 1.8E-52 T 12-10-2018 MIM_c21420 71b5a7ffc3628bfc6dcbb0f34bdbb085 280 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 70 280 32.957 T 12-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 MIM_c21420 71b5a7ffc3628bfc6dcbb0f34bdbb085 280 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 75 277 4.1E-56 T 12-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 MIM_c07020 458d8046b1c6ee0f6ace77356ae8f54b 266 SMART SM00382 40 241 8.3E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c07020 458d8046b1c6ee0f6ace77356ae8f54b 266 Pfam PF00005 ABC transporter 31 192 4.9E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c07020 458d8046b1c6ee0f6ace77356ae8f54b 266 Gene3D G3DSA:3.40.50.300 2 263 1.2E-58 T 12-10-2018 MIM_c07020 458d8046b1c6ee0f6ace77356ae8f54b 266 SUPERFAMILY SSF52540 14 263 3.26E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c07020 458d8046b1c6ee0f6ace77356ae8f54b 266 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 241 263 2.1E-10 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal MIM_c15160 8e36bb723a8b02e9d6376acfd4c0684d 452 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 23 452 3.2E-173 T 12-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 MIM_c15160 8e36bb723a8b02e9d6376acfd4c0684d 452 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 1 452 186.308 T 12-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 MIM_c15160 8e36bb723a8b02e9d6376acfd4c0684d 452 Pfam PF00583 Acetyltransferase (GNAT) family 344 413 8.7E-8 T 12-10-2018 IPR000182 GNAT domain MIM_c15160 8e36bb723a8b02e9d6376acfd4c0684d 452 Gene3D G3DSA:3.40.630.30 305 452 2.3E-36 T 12-10-2018 MIM_c15160 8e36bb723a8b02e9d6376acfd4c0684d 452 SUPERFAMILY SSF53633 21 303 1.06E-59 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MIM_c15160 8e36bb723a8b02e9d6376acfd4c0684d 452 SUPERFAMILY SSF55729 308 425 1.89E-18 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c15160 8e36bb723a8b02e9d6376acfd4c0684d 452 PIRSF PIRSF000423 13 452 1.9E-177 T 12-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 MIM_c15160 8e36bb723a8b02e9d6376acfd4c0684d 452 Pfam PF00696 Amino acid kinase family 40 277 4.1E-24 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 MIM_c15160 8e36bb723a8b02e9d6376acfd4c0684d 452 Gene3D G3DSA:3.40.1160.10 21 304 1.9E-81 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MIM_c22280 6d4a143205771ce848fc0d0085344753 182 Pfam PF13470 PIN domain 7 104 6.0E-7 T 12-10-2018 IPR002716 PIN domain MIM_c35080 9b2f55e65cf9b9d02328c9bfe16ab92e 365 Gene3D G3DSA:2.160.20.80 187 353 2.9E-29 T 12-10-2018 MIM_c35080 9b2f55e65cf9b9d02328c9bfe16ab92e 365 Pfam PF00805 Pentapeptide repeats (8 copies) 294 330 2.5E-6 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c35080 9b2f55e65cf9b9d02328c9bfe16ab92e 365 Gene3D G3DSA:2.160.20.100 8 186 3.3E-33 T 12-10-2018 MIM_c35080 9b2f55e65cf9b9d02328c9bfe16ab92e 365 Pfam PF13599 Pentapeptide repeats (9 copies) 41 124 1.8E-11 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c35080 9b2f55e65cf9b9d02328c9bfe16ab92e 365 Pfam PF13599 Pentapeptide repeats (9 copies) 192 256 1.6E-9 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c35080 9b2f55e65cf9b9d02328c9bfe16ab92e 365 SUPERFAMILY SSF141571 176 337 3.79E-29 T 12-10-2018 MIM_c35080 9b2f55e65cf9b9d02328c9bfe16ab92e 365 SUPERFAMILY SSF141571 16 185 3.53E-35 T 12-10-2018 MIM_c18190 5d01e24f5df25320a1ee04649f80d60a 673 SUPERFAMILY SSF46600 629 669 2.09E-10 T 12-10-2018 IPR036876 UVR domain superfamily MIM_c18190 5d01e24f5df25320a1ee04649f80d60a 673 Gene3D G3DSA:3.40.50.300 5 242 1.0E-70 T 12-10-2018 MIM_c18190 5d01e24f5df25320a1ee04649f80d60a 673 SMART SM00487 18 440 3.6E-28 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MIM_c18190 5d01e24f5df25320a1ee04649f80d60a 673 SMART SM00490 468 554 6.9E-20 T 12-10-2018 IPR001650 Helicase, C-terminal MIM_c18190 5d01e24f5df25320a1ee04649f80d60a 673 Pfam PF04851 Type III restriction enzyme, res subunit 26 146 2.5E-9 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MIM_c18190 5d01e24f5df25320a1ee04649f80d60a 673 Gene3D G3DSA:3.40.50.300 423 604 6.6E-49 T 12-10-2018 MIM_c18190 5d01e24f5df25320a1ee04649f80d60a 673 SUPERFAMILY SSF52540 13 423 1.93E-136 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c18190 5d01e24f5df25320a1ee04649f80d60a 673 Pfam PF02151 UvrB/uvrC motif 635 668 3.1E-8 T 12-10-2018 IPR001943 UVR domain GO:0005515 MIM_c18190 5d01e24f5df25320a1ee04649f80d60a 673 Gene3D G3DSA:4.10.860.10 621 672 1.1E-16 T 12-10-2018 MIM_c18190 5d01e24f5df25320a1ee04649f80d60a 673 Hamap MF_00204 UvrABC system protein B [uvrB]. 12 669 43.176 T 12-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 MIM_c18190 5d01e24f5df25320a1ee04649f80d60a 673 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 14 667 0.0 T 12-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 MIM_c18190 5d01e24f5df25320a1ee04649f80d60a 673 Pfam PF12344 Ultra-violet resistance protein B 560 602 3.6E-21 T 12-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain MIM_c18190 5d01e24f5df25320a1ee04649f80d60a 673 Gene3D G3DSA:3.40.50.300 272 422 2.5E-49 T 12-10-2018 MIM_c18190 5d01e24f5df25320a1ee04649f80d60a 673 Pfam PF00271 Helicase conserved C-terminal domain 452 552 1.7E-17 T 12-10-2018 IPR001650 Helicase, C-terminal MIM_c18190 5d01e24f5df25320a1ee04649f80d60a 673 SUPERFAMILY SSF52540 46 585 2.78E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c36570 d6a3af1f5b3674329386e5a1e66e1d14 603 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 205 342 7.5E-34 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MIM_c36570 d6a3af1f5b3674329386e5a1e66e1d14 603 SUPERFAMILY SSF52467 197 381 9.99E-43 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MIM_c36570 d6a3af1f5b3674329386e5a1e66e1d14 603 Gene3D G3DSA:3.40.50.970 393 586 2.0E-50 T 12-10-2018 MIM_c36570 d6a3af1f5b3674329386e5a1e66e1d14 603 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 20 186 1.7E-43 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MIM_c36570 d6a3af1f5b3674329386e5a1e66e1d14 603 SUPERFAMILY SSF52518 401 596 3.66E-49 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c36570 d6a3af1f5b3674329386e5a1e66e1d14 603 Gene3D G3DSA:3.40.50.1220 200 383 4.6E-48 T 12-10-2018 MIM_c36570 d6a3af1f5b3674329386e5a1e66e1d14 603 SUPERFAMILY SSF52518 18 192 1.18E-44 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c36570 d6a3af1f5b3674329386e5a1e66e1d14 603 TIGRFAM TIGR03457 sulphoacet_xsc: sulfoacetaldehyde acetyltransferase 19 599 0.0 T 12-10-2018 IPR017820 Sulphoacetaldehyde acetyltransferase GO:0000287|GO:0005737|GO:0019529|GO:0030976|GO:0050487 KEGG: 00430+2.3.3.15|MetaCyc: PWY-1281|MetaCyc: PWY-6637 MIM_c36570 d6a3af1f5b3674329386e5a1e66e1d14 603 Gene3D G3DSA:3.40.50.970 13 192 1.1E-48 T 12-10-2018 MIM_c36570 d6a3af1f5b3674329386e5a1e66e1d14 603 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 423 574 9.6E-35 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MIM_c26930 93846432ad9b6d0a973e818d9f936207 283 Pfam PF00551 Formyl transferase 88 264 5.8E-40 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MIM_c26930 93846432ad9b6d0a973e818d9f936207 283 PIRSF PIRSF036480 2 283 2.4E-113 T 12-10-2018 MIM_c26930 93846432ad9b6d0a973e818d9f936207 283 Gene3D G3DSA:3.40.50.170 87 282 3.7E-72 T 12-10-2018 MIM_c26930 93846432ad9b6d0a973e818d9f936207 283 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 6 282 2.1E-107 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MIM_c26930 93846432ad9b6d0a973e818d9f936207 283 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 88 110 1.8E-54 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MIM_c26930 93846432ad9b6d0a973e818d9f936207 283 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 7 33 1.8E-54 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MIM_c26930 93846432ad9b6d0a973e818d9f936207 283 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 110 137 1.8E-54 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MIM_c26930 93846432ad9b6d0a973e818d9f936207 283 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 256 281 1.8E-54 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MIM_c26930 93846432ad9b6d0a973e818d9f936207 283 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 39 51 1.8E-54 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MIM_c26930 93846432ad9b6d0a973e818d9f936207 283 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 234 256 1.8E-54 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MIM_c26930 93846432ad9b6d0a973e818d9f936207 283 Gene3D G3DSA:3.30.70.260 1 86 6.8E-27 T 12-10-2018 MIM_c26930 93846432ad9b6d0a973e818d9f936207 283 SUPERFAMILY SSF53328 88 282 3.79E-63 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MIM_c26930 93846432ad9b6d0a973e818d9f936207 283 SUPERFAMILY SSF55021 5 84 7.08E-17 T 12-10-2018 MIM_c26930 93846432ad9b6d0a973e818d9f936207 283 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 2 282 47.626 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MIM_c12560 1c04c34e9a6bf3b501a6710eb796a461 169 SUPERFAMILY SSF50891 6 166 3.21E-57 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily MIM_c12560 1c04c34e9a6bf3b501a6710eb796a461 169 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 45 57 1.6E-12 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MIM_c12560 1c04c34e9a6bf3b501a6710eb796a461 169 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 19 34 1.6E-12 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MIM_c12560 1c04c34e9a6bf3b501a6710eb796a461 169 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 122 137 1.6E-12 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MIM_c12560 1c04c34e9a6bf3b501a6710eb796a461 169 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 6 165 6.5E-47 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MIM_c12560 1c04c34e9a6bf3b501a6710eb796a461 169 PIRSF PIRSF001467 1 168 1.6E-25 T 12-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 MIM_c12560 1c04c34e9a6bf3b501a6710eb796a461 169 Gene3D G3DSA:2.40.100.10 2 167 5.6E-68 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily MIM_c12560 1c04c34e9a6bf3b501a6710eb796a461 169 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 40 57 - T 12-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 MIM_c03950 3ba209ea2582c15d2a3f25cd6984ffb6 239 SUPERFAMILY SSF55469 12 230 2.36E-49 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MIM_c03950 3ba209ea2582c15d2a3f25cd6984ffb6 239 Gene3D G3DSA:3.40.109.10 10 233 9.5E-72 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MIM_c03950 3ba209ea2582c15d2a3f25cd6984ffb6 239 Pfam PF00881 Nitroreductase family 18 207 3.6E-38 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MIM_c30160 648d9b827a28e89321c63161579629b8 414 Gene3D G3DSA:3.40.50.1110 164 413 1.7E-28 T 12-10-2018 IPR036514 SGNH hydrolase superfamily MIM_c30160 648d9b827a28e89321c63161579629b8 414 SUPERFAMILY SSF52266 198 411 8.55E-43 T 12-10-2018 MIM_c30160 648d9b827a28e89321c63161579629b8 414 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 205 400 2.2E-19 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain MIM_c29690 0bd6f2646a90670194934eb97567f556 581 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 169 328 4.3E-44 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MIM_c29690 0bd6f2646a90670194934eb97567f556 581 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 76 131 9.4E-12 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MIM_c29690 0bd6f2646a90670194934eb97567f556 581 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 352 415 5.4E-14 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MIM_c29690 0bd6f2646a90670194934eb97567f556 581 TIGRFAM TIGR02041 CysI: sulfite reductase (NADPH) hemoprotein, beta-component 15 558 1.4E-277 T 12-10-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MIM_c29690 0bd6f2646a90670194934eb97567f556 581 Gene3D G3DSA:3.30.413.10 191 335 1.2E-40 T 12-10-2018 MIM_c29690 0bd6f2646a90670194934eb97567f556 581 Hamap MF_01540 Sulfite reductase [NADPH] hemoprotein beta-component [cysI]. 6 570 57.242 T 12-10-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MIM_c29690 0bd6f2646a90670194934eb97567f556 581 SUPERFAMILY SSF56014 145 343 1.96E-54 T 12-10-2018 MIM_c29690 0bd6f2646a90670194934eb97567f556 581 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 430 556 0.045 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MIM_c29690 0bd6f2646a90670194934eb97567f556 581 SUPERFAMILY SSF56014 429 560 5.37E-32 T 12-10-2018 MIM_c29690 0bd6f2646a90670194934eb97567f556 581 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 477 493 - T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MIM_c29690 0bd6f2646a90670194934eb97567f556 581 Gene3D G3DSA:3.30.413.10 425 567 1.7E-33 T 12-10-2018 MIM_c29690 0bd6f2646a90670194934eb97567f556 581 SUPERFAMILY SSF55124 12 141 1.39E-24 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MIM_c29690 0bd6f2646a90670194934eb97567f556 581 Gene3D G3DSA:3.90.480.10 77 166 1.5E-22 T 12-10-2018 MIM_c29690 0bd6f2646a90670194934eb97567f556 581 Gene3D G3DSA:3.90.480.10 336 423 2.9E-31 T 12-10-2018 MIM_c29690 0bd6f2646a90670194934eb97567f556 581 PRINTS PR00397 Sirohaem Fe-binding site signature 477 495 1.2E-8 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MIM_c29690 0bd6f2646a90670194934eb97567f556 581 PRINTS PR00397 Sirohaem Fe-binding site signature 429 447 1.2E-8 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MIM_c29690 0bd6f2646a90670194934eb97567f556 581 SUPERFAMILY SSF55124 345 422 1.34E-21 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MIM_c32270 0e894bf29c26e4d769cb20af87c9ee48 124 Pfam PF03476 MOSC N-terminal beta barrel domain 26 110 5.1E-6 T 12-10-2018 IPR005303 MOSC, N-terminal beta barrel KEGG: 00790+2.8.1.9|MetaCyc: PWY-5963 MIM_c32270 0e894bf29c26e4d769cb20af87c9ee48 124 SUPERFAMILY SSF141673 8 120 2.62E-18 T 12-10-2018 MIM_c23340 7ae7f4491e1011b708b4cf36b9b9a75a 135 SUPERFAMILY SSF81301 1 109 2.78E-35 T 12-10-2018 MIM_c23340 7ae7f4491e1011b708b4cf36b9b9a75a 135 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 8 104 2.9E-32 T 12-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS MIM_c23340 7ae7f4491e1011b708b4cf36b9b9a75a 135 Gene3D G3DSA:3.30.460.10 1 116 6.8E-33 T 12-10-2018 MIM_c23340 7ae7f4491e1011b708b4cf36b9b9a75a 135 Pfam PF02410 Ribosomal silencing factor during starvation 10 104 3.0E-23 T 12-10-2018 MIM_c23340 7ae7f4491e1011b708b4cf36b9b9a75a 135 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 22.498 T 12-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS MIM_c10410 1a37f777afad79e286b2f865c0e8f03e 207 Pfam PF11161 Protein of unknown function (DUF2946) 1 204 3.0E-60 T 12-10-2018 IPR021332 Protein of unknown function DUF2944 MIM_c38570 5fb6b7231be61ebecff1baa84e210ee2 436 Pfam PF07690 Major Facilitator Superfamily 35 398 2.2E-48 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c38570 5fb6b7231be61ebecff1baa84e210ee2 436 Gene3D G3DSA:1.20.1250.20 11 436 1.5E-81 T 12-10-2018 MIM_c38570 5fb6b7231be61ebecff1baa84e210ee2 436 SUPERFAMILY SSF103473 13 435 1.57E-85 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c14500 bb915ff80c165c2a0609974490611c5c 572 Gene3D G3DSA:1.20.1730.10 56 557 1.4E-60 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily MIM_c14500 bb915ff80c165c2a0609974490611c5c 572 Pfam PF00474 Sodium:solute symporter family 68 489 8.9E-116 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MIM_c14500 bb915ff80c165c2a0609974490611c5c 572 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 68 489 6.2E-61 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MIM_c14500 bb915ff80c165c2a0609974490611c5c 572 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 183 208 - T 12-10-2018 IPR018212 Sodium/solute symporter, conserved site MIM_c05830 9cdba01932c26dd61b9c2d48f58e4823 154 SMART SM00347 33 133 2.6E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c05830 9cdba01932c26dd61b9c2d48f58e4823 154 ProSitePatterns PS01117 MarR-type HTH domain signature. 72 106 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MIM_c05830 9cdba01932c26dd61b9c2d48f58e4823 154 Gene3D G3DSA:1.10.10.10 3 149 1.4E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c05830 9cdba01932c26dd61b9c2d48f58e4823 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 4.0E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c05830 9cdba01932c26dd61b9c2d48f58e4823 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 4.0E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c05830 9cdba01932c26dd61b9c2d48f58e4823 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 4.0E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c05830 9cdba01932c26dd61b9c2d48f58e4823 154 Pfam PF01047 MarR family 40 97 1.9E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c05830 9cdba01932c26dd61b9c2d48f58e4823 154 SUPERFAMILY SSF46785 1 149 5.0E-30 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c11140 80b2eda7d79e2e8e589c3c3edf94f077 301 Gene3D G3DSA:3.40.190.10 176 276 1.1E-12 T 12-10-2018 MIM_c11140 80b2eda7d79e2e8e589c3c3edf94f077 301 Gene3D G3DSA:1.10.10.10 1 90 4.7E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c11140 80b2eda7d79e2e8e589c3c3edf94f077 301 Gene3D G3DSA:3.40.190.10 126 292 1.1E-12 T 12-10-2018 MIM_c11140 80b2eda7d79e2e8e589c3c3edf94f077 301 SUPERFAMILY SSF53850 94 296 1.03E-20 T 12-10-2018 MIM_c11140 80b2eda7d79e2e8e589c3c3edf94f077 301 SUPERFAMILY SSF46785 4 84 1.36E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c11140 80b2eda7d79e2e8e589c3c3edf94f077 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 2.1E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c11140 80b2eda7d79e2e8e589c3c3edf94f077 301 Pfam PF03466 LysR substrate binding domain 92 297 5.3E-21 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c14390 72206be46a21bab085299ab96f15e811 303 SUPERFAMILY SSF53850 93 293 3.55E-42 T 12-10-2018 MIM_c14390 72206be46a21bab085299ab96f15e811 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 2.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c14390 72206be46a21bab085299ab96f15e811 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 2.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c14390 72206be46a21bab085299ab96f15e811 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 2.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c14390 72206be46a21bab085299ab96f15e811 303 SUPERFAMILY SSF46785 2 84 7.21E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c14390 72206be46a21bab085299ab96f15e811 303 Pfam PF03466 LysR substrate binding domain 91 292 4.4E-46 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c14390 72206be46a21bab085299ab96f15e811 303 Gene3D G3DSA:3.40.190.290 93 296 3.1E-41 T 12-10-2018 MIM_c14390 72206be46a21bab085299ab96f15e811 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 1.7E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c14390 72206be46a21bab085299ab96f15e811 303 Gene3D G3DSA:1.10.10.10 1 87 3.9E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c32240 7844ed9413d7d321eb4c94f4d7d44abd 202 Gene3D G3DSA:3.40.50.150 6 197 5.3E-46 T 12-10-2018 MIM_c32240 7844ed9413d7d321eb4c94f4d7d44abd 202 Pfam PF03602 Conserved hypothetical protein 95 17 191 6.7E-40 T 12-10-2018 MIM_c32240 7844ed9413d7d321eb4c94f4d7d44abd 202 PIRSF PIRSF004553 16 195 2.4E-36 T 12-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 MIM_c32240 7844ed9413d7d321eb4c94f4d7d44abd 202 SUPERFAMILY SSF53335 17 195 1.92E-38 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c10530 1577f04692b2822cce45cbd2bc10563a 220 Gene3D G3DSA:3.90.320.10 1 212 1.6E-61 T 12-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal MIM_c10530 1577f04692b2822cce45cbd2bc10563a 220 SUPERFAMILY SSF52980 29 211 1.98E-15 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MIM_c07240 26d6db489d29e97c2480a24c0deb02d8 238 Gene3D G3DSA:3.40.50.2300 1 134 5.1E-35 T 12-10-2018 MIM_c07240 26d6db489d29e97c2480a24c0deb02d8 238 SMART SM00448 2 114 6.4E-33 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c07240 26d6db489d29e97c2480a24c0deb02d8 238 SUPERFAMILY SSF52172 1 121 2.28E-37 T 12-10-2018 IPR011006 CheY-like superfamily MIM_c07240 26d6db489d29e97c2480a24c0deb02d8 238 SUPERFAMILY SSF46689 171 231 3.63E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c07240 26d6db489d29e97c2480a24c0deb02d8 238 Pfam PF00072 Response regulator receiver domain 4 114 1.4E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c07240 26d6db489d29e97c2480a24c0deb02d8 238 Gene3D G3DSA:1.10.10.60 176 233 5.2E-13 T 12-10-2018 MIM_c36620 1429e7b1b5c156d585904a106ab70069 521 Pfam PF00392 Bacterial regulatory proteins, gntR family 42 104 9.8E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c36620 1429e7b1b5c156d585904a106ab70069 521 Gene3D G3DSA:1.10.10.10 33 105 7.3E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c36620 1429e7b1b5c156d585904a106ab70069 521 SUPERFAMILY SSF46785 36 108 8.5E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c36620 1429e7b1b5c156d585904a106ab70069 521 Gene3D G3DSA:3.40.640.10 139 505 1.9E-99 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c36620 1429e7b1b5c156d585904a106ab70069 521 SUPERFAMILY SSF53383 133 513 2.62E-86 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c36620 1429e7b1b5c156d585904a106ab70069 521 Pfam PF00155 Aminotransferase class I and II 215 477 7.3E-24 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MIM_c36620 1429e7b1b5c156d585904a106ab70069 521 SMART SM00345 45 104 2.8E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c25310 63ef2189ffec53d70557105152af63a0 214 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 3 144 7.5E-30 T 12-10-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO MIM_c25310 63ef2189ffec53d70557105152af63a0 214 Gene3D G3DSA:1.10.760.10 35 192 6.4E-41 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c25310 63ef2189ffec53d70557105152af63a0 214 SUPERFAMILY SSF46626 15 187 1.07E-19 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c34080 bd8b0aa690e0ba42d241971fc560dd7e 462 Gene3D G3DSA:3.40.190.10 192 449 2.5E-112 T 12-10-2018 MIM_c34080 bd8b0aa690e0ba42d241971fc560dd7e 462 SUPERFAMILY SSF53850 102 321 2.09E-37 T 12-10-2018 MIM_c34080 bd8b0aa690e0ba42d241971fc560dd7e 462 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 65 90 4.0E-5 T 12-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal MIM_c34080 bd8b0aa690e0ba42d241971fc560dd7e 462 Gene3D G3DSA:3.40.190.10 106 445 2.5E-112 T 12-10-2018 MIM_c34080 bd8b0aa690e0ba42d241971fc560dd7e 462 Pfam PF13379 NMT1-like family 100 338 5.5E-77 T 12-10-2018 MIM_c17340 07da2062c30dc9c0a4a7da7ee73581a6 302 SUPERFAMILY SSF53850 100 301 5.55E-37 T 12-10-2018 MIM_c17340 07da2062c30dc9c0a4a7da7ee73581a6 302 Pfam PF03466 LysR substrate binding domain 98 299 1.3E-40 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c17340 07da2062c30dc9c0a4a7da7ee73581a6 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 72 2.5E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c17340 07da2062c30dc9c0a4a7da7ee73581a6 302 SUPERFAMILY SSF46785 10 121 1.01E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c17340 07da2062c30dc9c0a4a7da7ee73581a6 302 Gene3D G3DSA:1.10.10.10 9 92 2.6E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c17340 07da2062c30dc9c0a4a7da7ee73581a6 302 Gene3D G3DSA:3.40.190.290 100 301 1.9E-43 T 12-10-2018 MIM_c17340 07da2062c30dc9c0a4a7da7ee73581a6 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 49 60 8.9E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c17340 07da2062c30dc9c0a4a7da7ee73581a6 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 49 8.9E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c17340 07da2062c30dc9c0a4a7da7ee73581a6 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 39 8.9E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c06790 6e7cae3faea917d844b2106b33b8b217 326 SUPERFAMILY SSF102114 57 323 1.7E-66 T 12-10-2018 MIM_c06790 6e7cae3faea917d844b2106b33b8b217 326 PIRSF PIRSF005963 1 325 7.0E-128 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MIM_c06790 6e7cae3faea917d844b2106b33b8b217 326 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 38 79 9.7E-7 T 12-10-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MIM_c06790 6e7cae3faea917d844b2106b33b8b217 326 Hamap MF_00206 Lipoyl synthase [lipA]. 1 326 150.424 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MIM_c06790 6e7cae3faea917d844b2106b33b8b217 326 Gene3D G3DSA:3.20.20.70 86 301 2.1E-17 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c06790 6e7cae3faea917d844b2106b33b8b217 326 SMART SM00729 90 299 8.8E-14 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MIM_c06790 6e7cae3faea917d844b2106b33b8b217 326 Pfam PF04055 Radical SAM superfamily 97 256 6.1E-14 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MIM_c06790 6e7cae3faea917d844b2106b33b8b217 326 TIGRFAM TIGR00510 lipA: lipoyl synthase 39 320 1.3E-127 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MIM_c05460 33c02dd280b5085e9c856172f47d19f8 163 SUPERFAMILY SSF52833 21 162 1.41E-34 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c05460 33c02dd280b5085e9c856172f47d19f8 163 Gene3D G3DSA:3.40.30.10 18 163 9.1E-37 T 12-10-2018 MIM_c05460 33c02dd280b5085e9c856172f47d19f8 163 Pfam PF08534 Redoxin 25 148 3.5E-23 T 12-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 MIM_c33750 281ff5c2bb1d34651e65e2bd8039a2bc 304 Pfam PF13533 Biotin-lipoyl like 47 94 2.1E-14 T 12-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain MIM_c33750 281ff5c2bb1d34651e65e2bd8039a2bc 304 Pfam PF13437 HlyD family secretion protein 155 238 7.2E-10 T 12-10-2018 MIM_c33750 281ff5c2bb1d34651e65e2bd8039a2bc 304 Gene3D G3DSA:2.40.30.170 172 294 7.8E-26 T 12-10-2018 MIM_c33750 281ff5c2bb1d34651e65e2bd8039a2bc 304 SUPERFAMILY SSF111369 44 187 2.75E-17 T 12-10-2018 MIM_c02850 30a1c462f5c784c5be4c953057934fb7 259 Gene3D G3DSA:3.40.30.10 121 259 4.0E-27 T 12-10-2018 MIM_c02850 30a1c462f5c784c5be4c953057934fb7 259 ProSitePatterns PS00194 Thioredoxin family active site. 154 172 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MIM_c02850 30a1c462f5c784c5be4c953057934fb7 259 Pfam PF08534 Redoxin 128 235 1.3E-9 T 12-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 MIM_c02850 30a1c462f5c784c5be4c953057934fb7 259 SUPERFAMILY SSF52833 98 256 1.5E-30 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c03510 ee8bc410e80a819011a230ce837a442c 211 PIRSF PIRSF001488 1 210 4.4E-50 T 12-10-2018 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL MIM_c03510 ee8bc410e80a819011a230ce837a442c 211 SUPERFAMILY SSF52833 43 193 5.34E-37 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c03510 ee8bc410e80a819011a230ce837a442c 211 Pfam PF13462 Thioredoxin 46 188 3.8E-13 T 12-10-2018 IPR012336 Thioredoxin-like fold MIM_c03510 ee8bc410e80a819011a230ce837a442c 211 Gene3D G3DSA:3.40.30.10 26 211 5.6E-49 T 12-10-2018 MIM_c21480 b3a1749cfcb57f859c5429964270bf8a 197 Gene3D G3DSA:3.30.230.30 4 128 1.7E-46 T 12-10-2018 IPR036956 Impact, N-terminal domain superfamily MIM_c21480 b3a1749cfcb57f859c5429964270bf8a 197 Pfam PF09186 Domain of unknown function (DUF1949) 135 191 8.8E-11 T 12-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal MIM_c21480 b3a1749cfcb57f859c5429964270bf8a 197 Pfam PF01205 Uncharacterized protein family UPF0029 19 119 8.1E-28 T 12-10-2018 IPR001498 Impact, N-terminal MIM_c21480 b3a1749cfcb57f859c5429964270bf8a 197 SUPERFAMILY SSF54211 7 122 7.97E-39 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MIM_c21480 b3a1749cfcb57f859c5429964270bf8a 197 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 74 103 - T 12-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site MIM_c21480 b3a1749cfcb57f859c5429964270bf8a 197 SUPERFAMILY SSF54980 132 195 4.17E-10 T 12-10-2018 IPR035647 EF-G domain III/V-like MIM_c08360 53273baaa54202cdb65ed471373e9673 347 Gene3D G3DSA:3.40.190.170 36 339 7.9E-83 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily MIM_c08360 53273baaa54202cdb65ed471373e9673 347 PIRSF PIRSF039026 3 347 3.8E-98 T 12-10-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like MIM_c08360 53273baaa54202cdb65ed471373e9673 347 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 54 321 5.2E-41 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 MIM_c08360 53273baaa54202cdb65ed471373e9673 347 Gene3D G3DSA:3.40.190.10 156 325 7.9E-83 T 12-10-2018 MIM_c32660 f2a8cb9a8fda6aa74dafa8f572f24498 240 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c32660 f2a8cb9a8fda6aa74dafa8f572f24498 240 SMART SM00382 29 216 4.1E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c32660 f2a8cb9a8fda6aa74dafa8f572f24498 240 Pfam PF00005 ABC transporter 21 165 7.8E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c32660 f2a8cb9a8fda6aa74dafa8f572f24498 240 SUPERFAMILY SSF52540 4 235 2.66E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c32660 f2a8cb9a8fda6aa74dafa8f572f24498 240 Gene3D G3DSA:3.40.50.300 2 238 4.4E-60 T 12-10-2018 MIM_c04830 d7590148439f0ebf8bc8bed42f14930b 418 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 415 1.1E-175 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MIM_c04830 d7590148439f0ebf8bc8bed42f14930b 418 Gene3D G3DSA:3.65.10.10 21 229 7.7E-164 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 MIM_c04830 d7590148439f0ebf8bc8bed42f14930b 418 SUPERFAMILY SSF55205 1 416 4.25E-138 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 MIM_c04830 d7590148439f0ebf8bc8bed42f14930b 418 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 406 1.1E-102 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MIM_c04830 d7590148439f0ebf8bc8bed42f14930b 418 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 416 44.039 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MIM_c04830 d7590148439f0ebf8bc8bed42f14930b 418 Gene3D G3DSA:3.65.10.10 6 413 7.7E-164 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 MIM_c35090 9b3871118bd497fc13c09c3cc43ba9f0 871 SUPERFAMILY SSF141571 552 685 5.1E-24 T 12-10-2018 MIM_c35090 9b3871118bd497fc13c09c3cc43ba9f0 871 Pfam PF00805 Pentapeptide repeats (8 copies) 559 595 1.5E-8 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c35090 9b3871118bd497fc13c09c3cc43ba9f0 871 Pfam PF00805 Pentapeptide repeats (8 copies) 804 841 2.0E-8 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c35090 9b3871118bd497fc13c09c3cc43ba9f0 871 Gene3D G3DSA:2.160.20.80 698 863 9.5E-19 T 12-10-2018 MIM_c35090 9b3871118bd497fc13c09c3cc43ba9f0 871 Gene3D G3DSA:2.160.20.100 537 696 6.0E-26 T 12-10-2018 MIM_c35090 9b3871118bd497fc13c09c3cc43ba9f0 871 SUPERFAMILY SSF141571 662 737 3.69E-7 T 12-10-2018 MIM_c35090 9b3871118bd497fc13c09c3cc43ba9f0 871 SUPERFAMILY SSF141571 747 853 1.1E-16 T 12-10-2018 MIM_c35090 9b3871118bd497fc13c09c3cc43ba9f0 871 Pfam PF13599 Pentapeptide repeats (9 copies) 609 683 2.0E-11 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c35090 9b3871118bd497fc13c09c3cc43ba9f0 871 Pfam PF09937 Uncharacterized protein conserved in bacteria (DUF2169) 20 301 2.6E-72 T 12-10-2018 IPR018683 Domain of unknown function DUF2169 MIM_c37010 26ca2bc78038bcfdbcb4ce7dcfabc33a 276 PIRSF PIRSF004750 2 276 2.1E-115 T 12-10-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MIM_c37010 26ca2bc78038bcfdbcb4ce7dcfabc33a 276 Pfam PF14819 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term 17 126 9.2E-44 T 12-10-2018 IPR029139 NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MIM_c37010 26ca2bc78038bcfdbcb4ce7dcfabc33a 276 Gene3D G3DSA:3.30.1130.10 139 276 1.7E-55 T 12-10-2018 MIM_c37010 26ca2bc78038bcfdbcb4ce7dcfabc33a 276 Pfam PF14489 QueF-like protein 189 263 1.2E-25 T 12-10-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MIM_c37010 26ca2bc78038bcfdbcb4ce7dcfabc33a 276 TIGRFAM TIGR03138 QueF: queuine synthase 7 276 7.0E-117 T 12-10-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MIM_c37010 26ca2bc78038bcfdbcb4ce7dcfabc33a 276 Gene3D G3DSA:3.30.1130.10 17 134 1.0E-41 T 12-10-2018 MIM_c37010 26ca2bc78038bcfdbcb4ce7dcfabc33a 276 Hamap MF_00817 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 276 136.338 T 12-10-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MIM_c37010 26ca2bc78038bcfdbcb4ce7dcfabc33a 276 SUPERFAMILY SSF55620 179 263 6.97E-10 T 12-10-2018 MIM_c10350 ace18b479836e08c1e6ffed4a06188dd 268 Pfam PF09339 IclR helix-turn-helix domain 28 76 3.8E-14 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c10350 ace18b479836e08c1e6ffed4a06188dd 268 Gene3D G3DSA:3.30.450.40 96 268 3.0E-53 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c10350 ace18b479836e08c1e6ffed4a06188dd 268 Gene3D G3DSA:1.10.10.10 22 95 7.5E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c10350 ace18b479836e08c1e6ffed4a06188dd 268 SUPERFAMILY SSF55781 82 267 5.17E-46 T 12-10-2018 MIM_c10350 ace18b479836e08c1e6ffed4a06188dd 268 SMART SM00346 25 114 2.5E-22 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c10350 ace18b479836e08c1e6ffed4a06188dd 268 SUPERFAMILY SSF46785 25 97 3.21E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c10350 ace18b479836e08c1e6ffed4a06188dd 268 Pfam PF01614 Bacterial transcriptional regulator 143 262 4.8E-31 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal MIM_c08740 b019370a73ff0b3239dfefa367a859ee 128 Gene3D G3DSA:3.30.429.10 63 127 1.1E-6 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily MIM_c08740 b019370a73ff0b3239dfefa367a859ee 128 Gene3D G3DSA:3.30.429.10 1 62 7.2E-13 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily MIM_c08740 b019370a73ff0b3239dfefa367a859ee 128 Pfam PF01361 Tautomerase enzyme 2 57 6.3E-8 T 12-10-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 MIM_c08740 b019370a73ff0b3239dfefa367a859ee 128 SUPERFAMILY SSF55331 2 118 1.08E-12 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily MIM_c36510 1d090bc492171e86f4737640e257a45e 442 Gene3D G3DSA:1.20.1250.20 8 431 1.5E-57 T 12-10-2018 MIM_c36510 1d090bc492171e86f4737640e257a45e 442 SUPERFAMILY SSF103473 1 420 2.22E-63 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c36510 1d090bc492171e86f4737640e257a45e 442 Pfam PF07690 Major Facilitator Superfamily 249 416 5.0E-13 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c36510 1d090bc492171e86f4737640e257a45e 442 Pfam PF00083 Sugar (and other) transporter 13 223 3.4E-25 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MIM_c34460 945fb4bb544a0f3ebf72f826e2ea9754 269 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 45 257 8.3E-26 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c34460 945fb4bb544a0f3ebf72f826e2ea9754 269 SUPERFAMILY SSF53850 43 257 2.53E-34 T 12-10-2018 MIM_c34460 945fb4bb544a0f3ebf72f826e2ea9754 269 Gene3D G3DSA:3.40.190.10 129 220 8.0E-29 T 12-10-2018 MIM_c34460 945fb4bb544a0f3ebf72f826e2ea9754 269 SMART SM00062 42 262 1.2E-17 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c34460 945fb4bb544a0f3ebf72f826e2ea9754 269 Gene3D G3DSA:3.40.190.10 40 254 8.0E-29 T 12-10-2018 MIM_c41030 da697ef4fc58796111e408c0a206d4bc 347 SUPERFAMILY SSF111369 148 328 7.19E-9 T 12-10-2018 MIM_c41030 da697ef4fc58796111e408c0a206d4bc 347 Gene3D G3DSA:2.40.30.170 225 334 1.1E-22 T 12-10-2018 MIM_c41030 da697ef4fc58796111e408c0a206d4bc 347 SUPERFAMILY SSF111369 45 132 1.22E-7 T 12-10-2018 MIM_c41030 da697ef4fc58796111e408c0a206d4bc 347 Gene3D G3DSA:2.40.50.100 43 76 1.2E-11 T 12-10-2018 MIM_c41030 da697ef4fc58796111e408c0a206d4bc 347 Gene3D G3DSA:1.10.287.470 111 178 4.4E-8 T 12-10-2018 MIM_c41030 da697ef4fc58796111e408c0a206d4bc 347 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 45 323 3.0E-13 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MIM_c41030 da697ef4fc58796111e408c0a206d4bc 347 Gene3D G3DSA:1.10.287.470 77 101 1.2E-11 T 12-10-2018 MIM_c16980 31a3b1c5104db8f814a24ca221238eda 305 Gene3D G3DSA:3.40.50.1100 8 298 9.5E-109 T 12-10-2018 MIM_c16980 31a3b1c5104db8f814a24ca221238eda 305 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 286 1.6E-61 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MIM_c16980 31a3b1c5104db8f814a24ca221238eda 305 Gene3D G3DSA:3.40.50.1100 43 144 9.5E-109 T 12-10-2018 MIM_c16980 31a3b1c5104db8f814a24ca221238eda 305 SUPERFAMILY SSF53686 3 299 4.06E-88 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MIM_c16980 31a3b1c5104db8f814a24ca221238eda 305 TIGRFAM TIGR01136 cysKM: cysteine synthase 7 300 2.0E-113 T 12-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MIM_c16980 31a3b1c5104db8f814a24ca221238eda 305 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 300 2.1E-116 T 12-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MIM_c09860 58c5de96116b47402be1b6e7fdfed604 493 SUPERFAMILY SSF161093 321 492 8.63E-43 T 12-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 MIM_c09860 58c5de96116b47402be1b6e7fdfed604 493 Pfam PF03448 MgtE intracellular N domain 78 178 7.7E-23 T 12-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain MIM_c09860 58c5de96116b47402be1b6e7fdfed604 493 Gene3D G3DSA:1.25.60.10 48 176 5.8E-15 T 12-10-2018 IPR038076 MgtE, N-terminal domain superfamily MIM_c09860 58c5de96116b47402be1b6e7fdfed604 493 Pfam PF01769 Divalent cation transporter 364 485 1.8E-22 T 12-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 MIM_c09860 58c5de96116b47402be1b6e7fdfed604 493 Gene3D G3DSA:3.10.580.10 177 304 7.1E-42 T 12-10-2018 MIM_c09860 58c5de96116b47402be1b6e7fdfed604 493 Pfam PF00571 CBS domain 181 237 3.8E-4 T 12-10-2018 IPR000644 CBS domain MIM_c09860 58c5de96116b47402be1b6e7fdfed604 493 Pfam PF00571 CBS domain 245 299 2.8E-5 T 12-10-2018 IPR000644 CBS domain MIM_c09860 58c5de96116b47402be1b6e7fdfed604 493 SMART SM00924 78 181 2.0E-34 T 12-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain MIM_c09860 58c5de96116b47402be1b6e7fdfed604 493 SUPERFAMILY SSF158791 56 178 4.05E-25 T 12-10-2018 MIM_c09860 58c5de96116b47402be1b6e7fdfed604 493 Gene3D G3DSA:1.10.357.20 319 492 1.5E-45 T 12-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain MIM_c09860 58c5de96116b47402be1b6e7fdfed604 493 SUPERFAMILY SSF54631 180 314 4.51E-27 T 12-10-2018 MIM_c09860 58c5de96116b47402be1b6e7fdfed604 493 TIGRFAM TIGR00400 mgtE: magnesium transporter 61 492 3.4E-82 T 12-10-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 MIM_c09860 58c5de96116b47402be1b6e7fdfed604 493 SMART SM00116 252 300 0.39 T 12-10-2018 IPR000644 CBS domain MIM_c09860 58c5de96116b47402be1b6e7fdfed604 493 SMART SM00116 188 241 4.2 T 12-10-2018 IPR000644 CBS domain MIM_c31210 b9af87700a8f16dd48fec5efe624870c 296 Pfam PF06719 AraC-type transcriptional regulator N-terminus 22 172 3.3E-43 T 12-10-2018 IPR009594 Transcription regulator HTH, AraC, N-terminal MIM_c31210 b9af87700a8f16dd48fec5efe624870c 296 Pfam PF12833 Helix-turn-helix domain 207 282 1.0E-17 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c31210 b9af87700a8f16dd48fec5efe624870c 296 SUPERFAMILY SSF46689 185 235 4.0E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c31210 b9af87700a8f16dd48fec5efe624870c 296 SUPERFAMILY SSF46689 237 287 3.63E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c31210 b9af87700a8f16dd48fec5efe624870c 296 SMART SM00342 201 284 1.6E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c31210 b9af87700a8f16dd48fec5efe624870c 296 Gene3D G3DSA:1.10.10.60 184 289 8.3E-25 T 12-10-2018 MIM_c01090 eb8063cb267d20038d351f2a3fa52454 254 Pfam PF00455 DeoR C terminal sensor domain 75 232 1.8E-50 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain MIM_c01090 eb8063cb267d20038d351f2a3fa52454 254 SMART SM00419 12 60 0.0013 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MIM_c01090 eb8063cb267d20038d351f2a3fa52454 254 SMART SM01134 73 234 1.9E-68 T 12-10-2018 MIM_c01090 eb8063cb267d20038d351f2a3fa52454 254 Pfam PF08220 DeoR-like helix-turn-helix domain 6 62 1.2E-18 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MIM_c01090 eb8063cb267d20038d351f2a3fa52454 254 SMART SM00420 6 58 1.8E-17 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MIM_c01090 eb8063cb267d20038d351f2a3fa52454 254 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.1E-8 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MIM_c01090 eb8063cb267d20038d351f2a3fa52454 254 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.1E-8 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MIM_c01090 eb8063cb267d20038d351f2a3fa52454 254 SUPERFAMILY SSF100950 73 234 2.51E-27 T 12-10-2018 IPR037171 NagB/RpiA transferase-like MIM_c01090 eb8063cb267d20038d351f2a3fa52454 254 SUPERFAMILY SSF46785 3 66 1.91E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c01090 eb8063cb267d20038d351f2a3fa52454 254 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 MIM_c01090 eb8063cb267d20038d351f2a3fa52454 254 Gene3D G3DSA:1.10.10.10 7 52 2.3E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c13400 d32416d9c97fba804968870dcd54b8f0 337 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 334 3.3E-47 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c13400 d32416d9c97fba804968870dcd54b8f0 337 SUPERFAMILY SSF161098 92 321 2.75E-20 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c13400 d32416d9c97fba804968870dcd54b8f0 337 Gene3D G3DSA:1.10.3720.10 88 330 6.4E-29 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c11190 b51d9ba52a2718ac0b99097e8955ab55 325 Gene3D G3DSA:3.40.190.10 126 249 1.9E-93 T 12-10-2018 MIM_c11190 b51d9ba52a2718ac0b99097e8955ab55 325 SUPERFAMILY SSF53850 110 286 9.46E-11 T 12-10-2018 MIM_c11190 b51d9ba52a2718ac0b99097e8955ab55 325 Gene3D G3DSA:3.40.190.150 28 314 1.9E-93 T 12-10-2018 MIM_c11190 b51d9ba52a2718ac0b99097e8955ab55 325 PIRSF PIRSF017082 1 324 3.5E-69 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c11190 b51d9ba52a2718ac0b99097e8955ab55 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 320 1.4E-64 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c04220 80d2e9c5d6c603aa0b7dc9d37abd94e8 321 SUPERFAMILY SSF103481 60 147 8.76E-5 T 12-10-2018 MIM_c04220 80d2e9c5d6c603aa0b7dc9d37abd94e8 321 SUPERFAMILY SSF103481 197 298 6.28E-14 T 12-10-2018 MIM_c04220 80d2e9c5d6c603aa0b7dc9d37abd94e8 321 Pfam PF00892 EamA-like transporter family 161 295 2.1E-19 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MIM_c04220 80d2e9c5d6c603aa0b7dc9d37abd94e8 321 Pfam PF00892 EamA-like transporter family 10 142 4.5E-8 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MIM_c11850 b8f662f19482c9784d69b1d87f669314 410 Gene3D G3DSA:1.20.1250.20 2 195 4.1E-32 T 12-10-2018 MIM_c11850 b8f662f19482c9784d69b1d87f669314 410 Pfam PF07690 Major Facilitator Superfamily 14 353 1.0E-36 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c11850 b8f662f19482c9784d69b1d87f669314 410 SUPERFAMILY SSF103473 5 398 6.41E-55 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c11850 b8f662f19482c9784d69b1d87f669314 410 Gene3D G3DSA:1.20.1250.20 199 400 5.6E-14 T 12-10-2018 MIM_c24890 6156e42ac8ba4cc1505759677df146ad 216 Gene3D G3DSA:1.20.1050.10 88 204 1.7E-40 T 12-10-2018 MIM_c24890 6156e42ac8ba4cc1505759677df146ad 216 SUPERFAMILY SSF47616 84 205 4.59E-20 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MIM_c24890 6156e42ac8ba4cc1505759677df146ad 216 SUPERFAMILY SSF52833 22 83 1.51E-16 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c24890 6156e42ac8ba4cc1505759677df146ad 216 Gene3D G3DSA:3.40.30.10 2 87 3.2E-35 T 12-10-2018 MIM_c24890 6156e42ac8ba4cc1505759677df146ad 216 Pfam PF02798 Glutathione S-transferase, N-terminal domain 20 81 9.1E-13 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MIM_c17100 8ea6a7587e4565a730741d811f7e9ce8 200 Gene3D G3DSA:3.40.30.10 4 193 2.9E-59 T 12-10-2018 MIM_c17100 8ea6a7587e4565a730741d811f7e9ce8 200 Pfam PF13409 Glutathione S-transferase, N-terminal domain 9 76 1.4E-15 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MIM_c17100 8ea6a7587e4565a730741d811f7e9ce8 200 Gene3D G3DSA:1.20.1050.10 82 191 2.9E-59 T 12-10-2018 MIM_c17100 8ea6a7587e4565a730741d811f7e9ce8 200 SUPERFAMILY SSF52833 1 79 4.17E-16 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c17100 8ea6a7587e4565a730741d811f7e9ce8 200 SUPERFAMILY SSF47616 73 198 2.76E-10 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MIM_c15430 e6608555ede0bec9746300f97bdabafd 417 Gene3D G3DSA:3.30.9.10 134 364 1.3E-45 T 12-10-2018 MIM_c15430 e6608555ede0bec9746300f97bdabafd 417 SUPERFAMILY SSF51905 1 408 9.06E-46 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c15430 e6608555ede0bec9746300f97bdabafd 417 SUPERFAMILY SSF54373 271 361 2.35E-15 T 12-10-2018 MIM_c15430 e6608555ede0bec9746300f97bdabafd 417 Gene3D G3DSA:3.50.50.60 97 402 1.3E-45 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c15430 e6608555ede0bec9746300f97bdabafd 417 Gene3D G3DSA:3.50.50.60 1 54 1.8E-11 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c15430 e6608555ede0bec9746300f97bdabafd 417 Pfam PF01266 FAD dependent oxidoreductase 2 398 5.9E-62 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MIM_c21800 5ae71004d188691e3bbb2c1df6bc93af 110 SUPERFAMILY SSF47729 8 100 7.07E-33 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 MIM_c21800 5ae71004d188691e3bbb2c1df6bc93af 110 Pfam PF00216 Bacterial DNA-binding protein 8 96 1.1E-30 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MIM_c21800 5ae71004d188691e3bbb2c1df6bc93af 110 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 6 102 29.519 T 12-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 MIM_c21800 5ae71004d188691e3bbb2c1df6bc93af 110 Gene3D G3DSA:4.10.520.10 6 102 4.7E-36 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 MIM_c21800 5ae71004d188691e3bbb2c1df6bc93af 110 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 53 72 - T 12-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 MIM_c21800 5ae71004d188691e3bbb2c1df6bc93af 110 PRINTS PR01727 Prokaryotic integration host factor signature 47 62 2.6E-13 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MIM_c21800 5ae71004d188691e3bbb2c1df6bc93af 110 PRINTS PR01727 Prokaryotic integration host factor signature 65 78 2.6E-13 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MIM_c21800 5ae71004d188691e3bbb2c1df6bc93af 110 PRINTS PR01727 Prokaryotic integration host factor signature 81 95 2.6E-13 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MIM_c21800 5ae71004d188691e3bbb2c1df6bc93af 110 SMART SM00411 8 97 2.9E-42 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MIM_c21800 5ae71004d188691e3bbb2c1df6bc93af 110 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 7 98 8.4E-42 T 12-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 MIM_c19140 5caa8db06669a2530c1b7c3c985af458 251 SUPERFAMILY SSF47616 83 216 4.18E-19 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MIM_c19140 5caa8db06669a2530c1b7c3c985af458 251 Pfam PF00043 Glutathione S-transferase, C-terminal domain 146 207 5.3E-6 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal MIM_c19140 5caa8db06669a2530c1b7c3c985af458 251 SUPERFAMILY SSF52833 1 84 6.87E-19 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c19140 5caa8db06669a2530c1b7c3c985af458 251 Gene3D G3DSA:3.40.30.10 1 82 7.8E-33 T 12-10-2018 MIM_c19140 5caa8db06669a2530c1b7c3c985af458 251 Pfam PF02798 Glutathione S-transferase, N-terminal domain 4 74 1.3E-15 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MIM_c19140 5caa8db06669a2530c1b7c3c985af458 251 Gene3D G3DSA:1.20.1050.10 84 213 2.2E-24 T 12-10-2018 MIM_c35060 248a306618d2e51f83f88c1da7463ae7 447 Pfam PF00296 Luciferase-like monooxygenase 30 392 2.2E-55 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MIM_c35060 248a306618d2e51f83f88c1da7463ae7 447 PIRSF PIRSF000337 2 445 4.7E-134 T 12-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MIM_c35060 248a306618d2e51f83f88c1da7463ae7 447 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 7 434 2.8E-152 T 12-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MIM_c35060 248a306618d2e51f83f88c1da7463ae7 447 SUPERFAMILY SSF51679 1 440 1.7E-115 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MIM_c35060 248a306618d2e51f83f88c1da7463ae7 447 Gene3D G3DSA:3.20.20.30 1 444 7.4E-133 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MIM_24p00030 a88cf2044b8e7516cf7f3c0b0148bbe4 142 Gene3D G3DSA:2.10.109.10 27 141 1.5E-41 T 12-10-2018 MIM_24p00030 a88cf2044b8e7516cf7f3c0b0148bbe4 142 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 93 105 4.0E-9 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MIM_24p00030 a88cf2044b8e7516cf7f3c0b0148bbe4 142 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 65 76 4.0E-9 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MIM_24p00030 a88cf2044b8e7516cf7f3c0b0148bbe4 142 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 54 64 4.0E-9 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MIM_24p00030 a88cf2044b8e7516cf7f3c0b0148bbe4 142 SUPERFAMILY SSF51306 24 139 4.01E-32 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily MIM_24p00030 a88cf2044b8e7516cf7f3c0b0148bbe4 142 Pfam PF00717 Peptidase S24-like 58 120 8.0E-14 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MIM_c18980 bb34bae0749cc83102807950a290ea91 554 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 275 1.2E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c18980 bb34bae0749cc83102807950a290ea91 554 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 355 543 5.9E-8 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c18980 bb34bae0749cc83102807950a290ea91 554 SUPERFAMILY SSF161098 13 270 1.42E-39 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c18980 bb34bae0749cc83102807950a290ea91 554 Gene3D G3DSA:1.10.3720.10 290 552 4.1E-38 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c18980 bb34bae0749cc83102807950a290ea91 554 Gene3D G3DSA:1.10.3720.10 18 277 2.6E-48 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c18980 bb34bae0749cc83102807950a290ea91 554 SUPERFAMILY SSF161098 292 547 7.09E-40 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c04060 4d1d32deb545a873543654278067bf33 802 Pfam PF01011 PQQ enzyme repeat 731 765 5.6E-6 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat MIM_c04060 4d1d32deb545a873543654278067bf33 802 Pfam PF01011 PQQ enzyme repeat 218 245 4.5E-5 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat MIM_c04060 4d1d32deb545a873543654278067bf33 802 SMART SM00564 724 756 18.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c04060 4d1d32deb545a873543654278067bf33 802 SMART SM00564 345 387 0.049 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c04060 4d1d32deb545a873543654278067bf33 802 SMART SM00564 415 467 0.036 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c04060 4d1d32deb545a873543654278067bf33 802 SMART SM00564 289 320 250.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c04060 4d1d32deb545a873543654278067bf33 802 SMART SM00564 213 244 1.1E-6 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c04060 4d1d32deb545a873543654278067bf33 802 TIGRFAM TIGR03074 PQQ_membr_DH: membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family 5 800 0.0 T 12-10-2018 IPR017511 PQQ-dependent membrane bound dehydrogenase GO:0016021|GO:0016614|GO:0048038|GO:0055114 MIM_c04060 4d1d32deb545a873543654278067bf33 802 Gene3D G3DSA:2.140.10.10 567 802 3.7E-32 T 12-10-2018 MIM_c04060 4d1d32deb545a873543654278067bf33 802 SUPERFAMILY SSF50998 156 800 3.66E-134 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MIM_c04060 4d1d32deb545a873543654278067bf33 802 Pfam PF13360 PQQ-like domain 294 398 4.9E-6 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat MIM_c04060 4d1d32deb545a873543654278067bf33 802 Gene3D G3DSA:2.140.10.10 151 566 1.4E-106 T 12-10-2018 MIM_c02040 c6dd672087c402653065503029979663 276 Pfam PF00561 alpha/beta hydrolase fold 35 258 8.1E-18 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c02040 c6dd672087c402653065503029979663 276 SUPERFAMILY SSF53474 10 271 1.4E-46 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c02040 c6dd672087c402653065503029979663 276 Gene3D G3DSA:3.40.50.1820 7 265 5.5E-68 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c04620 54387a601f309ef312723b5d3353c6a2 217 Pfam PF02630 SCO1/SenC 62 195 3.7E-40 T 12-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c04620 54387a601f309ef312723b5d3353c6a2 217 Gene3D G3DSA:3.40.30.10 53 217 8.2E-54 T 12-10-2018 MIM_c04620 54387a601f309ef312723b5d3353c6a2 217 SUPERFAMILY SSF52833 62 217 2.87E-50 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c27860 41aee97383425b2cc0ff0f69b86fdeaa 384 SUPERFAMILY SSF53383 1 384 1.48E-109 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c27860 41aee97383425b2cc0ff0f69b86fdeaa 384 Pfam PF00155 Aminotransferase class I and II 32 380 1.5E-62 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MIM_c27860 41aee97383425b2cc0ff0f69b86fdeaa 384 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 MIM_c27860 41aee97383425b2cc0ff0f69b86fdeaa 384 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 162 186 8.5E-11 T 12-10-2018 MIM_c27860 41aee97383425b2cc0ff0f69b86fdeaa 384 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 115 136 8.5E-11 T 12-10-2018 MIM_c27860 41aee97383425b2cc0ff0f69b86fdeaa 384 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 93 113 8.5E-11 T 12-10-2018 MIM_c27860 41aee97383425b2cc0ff0f69b86fdeaa 384 Gene3D G3DSA:3.40.640.10 5 384 1.9E-122 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c13010 e495abc90d153ae8eb2882925903fa88 420 Gene3D G3DSA:3.30.70.260 264 413 1.6E-56 T 12-10-2018 MIM_c13010 e495abc90d153ae8eb2882925903fa88 420 Gene3D G3DSA:3.40.1160.10 1 263 7.7E-89 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MIM_c13010 e495abc90d153ae8eb2882925903fa88 420 PRINTS PR00474 Glutamate 5-kinase family signature 33 47 4.8E-5 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MIM_c13010 e495abc90d153ae8eb2882925903fa88 420 PRINTS PR00474 Glutamate 5-kinase family signature 152 179 4.8E-5 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MIM_c13010 e495abc90d153ae8eb2882925903fa88 420 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 1 412 2.4E-128 T 12-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MIM_c13010 e495abc90d153ae8eb2882925903fa88 420 SUPERFAMILY SSF55021 257 335 7.1E-17 T 12-10-2018 MIM_c13010 e495abc90d153ae8eb2882925903fa88 420 Pfam PF13840 ACT domain 346 409 3.7E-15 T 12-10-2018 IPR027795 CASTOR, ACT domain MIM_c13010 e495abc90d153ae8eb2882925903fa88 420 SUPERFAMILY SSF55021 339 414 5.5E-24 T 12-10-2018 MIM_c13010 e495abc90d153ae8eb2882925903fa88 420 Gene3D G3DSA:3.30.70.260 270 348 1.6E-56 T 12-10-2018 MIM_c13010 e495abc90d153ae8eb2882925903fa88 420 SUPERFAMILY SSF53633 4 250 2.88E-76 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MIM_c13010 e495abc90d153ae8eb2882925903fa88 420 Pfam PF00696 Amino acid kinase family 3 229 1.0E-51 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 MIM_c13010 e495abc90d153ae8eb2882925903fa88 420 Pfam PF01842 ACT domain 277 331 3.8E-9 T 12-10-2018 IPR002912 ACT domain MIM_c13010 e495abc90d153ae8eb2882925903fa88 420 PIRSF PIRSF000726 60 420 8.8E-137 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MIM_c13010 e495abc90d153ae8eb2882925903fa88 420 PIRSF PIRSF000726 1 62 8.8E-22 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MIM_c13010 e495abc90d153ae8eb2882925903fa88 420 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 12-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MIM_c13010 e495abc90d153ae8eb2882925903fa88 420 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 412 2.8E-126 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MIM_c26380 6e4e98d1dbd3b6b121008764deaf1d9b 323 Gene3D G3DSA:3.40.50.300 3 322 1.9E-98 T 12-10-2018 MIM_c26380 6e4e98d1dbd3b6b121008764deaf1d9b 323 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c26380 6e4e98d1dbd3b6b121008764deaf1d9b 323 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 299 1.2E-18 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c26380 6e4e98d1dbd3b6b121008764deaf1d9b 323 SUPERFAMILY SSF52540 6 254 1.57E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c26380 6e4e98d1dbd3b6b121008764deaf1d9b 323 SMART SM00382 40 232 2.3E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c26380 6e4e98d1dbd3b6b121008764deaf1d9b 323 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 318 1.9E-27 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c26380 6e4e98d1dbd3b6b121008764deaf1d9b 323 Pfam PF00005 ABC transporter 31 183 1.1E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c19150 2d0a47924216e7cb1b5869cb15d97fa0 200 Gene3D G3DSA:3.40.30.10 36 200 1.2E-47 T 12-10-2018 MIM_c19150 2d0a47924216e7cb1b5869cb15d97fa0 200 Pfam PF02630 SCO1/SenC 44 178 2.9E-37 T 12-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c19150 2d0a47924216e7cb1b5869cb15d97fa0 200 SUPERFAMILY SSF52833 44 200 5.28E-46 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c34840 8bb6166f58800a91f0d3f14104008187 142 SUPERFAMILY SSF82784 1 139 5.23E-45 T 12-10-2018 IPR036102 OsmC/Ohr superfamily MIM_c34840 8bb6166f58800a91f0d3f14104008187 142 Pfam PF02566 OsmC-like protein 44 138 1.4E-16 T 12-10-2018 IPR003718 OsmC/Ohr family MIM_c34840 8bb6166f58800a91f0d3f14104008187 142 Gene3D G3DSA:2.20.25.10 1 47 1.8E-24 T 12-10-2018 MIM_c34840 8bb6166f58800a91f0d3f14104008187 142 Gene3D G3DSA:3.30.300.20 48 140 2.0E-32 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta MIM_c34840 8bb6166f58800a91f0d3f14104008187 142 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 7 139 3.1E-55 T 12-10-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 Gene3D G3DSA:3.30.230.10 234 413 8.8E-45 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 PRINTS PR00418 DNA topoisomerase II family signature 545 557 2.2E-60 T 12-10-2018 MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 PRINTS PR00418 DNA topoisomerase II family signature 290 303 2.2E-60 T 12-10-2018 MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 PRINTS PR00418 DNA topoisomerase II family signature 525 542 2.2E-60 T 12-10-2018 MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 PRINTS PR00418 DNA topoisomerase II family signature 507 523 2.2E-60 T 12-10-2018 MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 PRINTS PR00418 DNA topoisomerase II family signature 598 614 2.2E-60 T 12-10-2018 MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 PRINTS PR00418 DNA topoisomerase II family signature 44 59 2.2E-60 T 12-10-2018 MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 PRINTS PR00418 DNA topoisomerase II family signature 125 139 2.2E-60 T 12-10-2018 MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 PRINTS PR00418 DNA topoisomerase II family signature 79 92 2.2E-60 T 12-10-2018 MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 PRINTS PR00418 DNA topoisomerase II family signature 438 452 2.2E-60 T 12-10-2018 MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 ProSitePatterns PS00177 DNA topoisomerase II signature. 440 448 - T 12-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 Gene3D G3DSA:3.40.50.670 414 661 5.9E-83 T 12-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 SUPERFAMILY SSF55874 18 233 1.57E-60 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 SUPERFAMILY SSF54211 236 411 4.93E-36 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 15 666 43.429 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 Gene3D G3DSA:3.30.565.10 15 233 4.8E-72 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 47 188 2.7E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 SMART SM00387 41 191 2.6E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 595 658 1.6E-24 T 12-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 Pfam PF01751 Toprim domain 437 550 5.1E-12 T 12-10-2018 IPR006171 TOPRIM domain MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 SMART SM00433 46 662 5.2E-192 T 12-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 PRINTS PR01098 Topoisomerase IV subunit B signature 386 411 4.6E-37 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 PRINTS PR01098 Topoisomerase IV subunit B signature 335 350 4.6E-37 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 PRINTS PR01098 Topoisomerase IV subunit B signature 39 52 4.6E-37 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 PRINTS PR01098 Topoisomerase IV subunit B signature 472 493 4.6E-37 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 PRINTS PR01098 Topoisomerase IV subunit B signature 318 334 4.6E-37 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 PRINTS PR01098 Topoisomerase IV subunit B signature 362 385 4.6E-37 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 PRINTS PR01098 Topoisomerase IV subunit B signature 210 231 4.6E-37 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 PRINTS PR01098 Topoisomerase IV subunit B signature 192 209 4.6E-37 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 SUPERFAMILY SSF56719 413 659 3.66E-73 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MIM_c18420 2d2a2ba0770c0e52b80bee6816a46391 668 Pfam PF00204 DNA gyrase B 236 409 5.7E-33 T 12-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MIM_c02880 ed6310c043c7c9478b4a703437eaf419 616 Pfam PF00580 UvrD/REP helicase N-terminal domain 14 296 4.2E-18 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 MIM_c02880 ed6310c043c7c9478b4a703437eaf419 616 Gene3D G3DSA:3.40.50.300 7 144 3.8E-12 T 12-10-2018 MIM_c02880 ed6310c043c7c9478b4a703437eaf419 616 SUPERFAMILY SSF52540 12 613 3.29E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c02880 ed6310c043c7c9478b4a703437eaf419 616 Pfam PF13538 UvrD-like helicase C-terminal domain 558 608 1.2E-8 T 12-10-2018 IPR027785 UvrD-like helicase C-terminal domain MIM_c02880 ed6310c043c7c9478b4a703437eaf419 616 Gene3D G3DSA:3.40.50.300 536 615 1.0E-11 T 12-10-2018 MIM_c02880 ed6310c043c7c9478b4a703437eaf419 616 Gene3D G3DSA:3.40.50.300 204 331 2.1E-17 T 12-10-2018 MIM_c20930 b52941d4aa1c3bc463df64434b4b3607 322 SUPERFAMILY SSF53850 92 284 1.09E-14 T 12-10-2018 MIM_c20930 b52941d4aa1c3bc463df64434b4b3607 322 Gene3D G3DSA:3.40.190.10 124 247 5.9E-98 T 12-10-2018 MIM_c20930 b52941d4aa1c3bc463df64434b4b3607 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 318 2.9E-73 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c20930 b52941d4aa1c3bc463df64434b4b3607 322 PIRSF PIRSF017082 1 321 1.1E-74 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c20930 b52941d4aa1c3bc463df64434b4b3607 322 Gene3D G3DSA:3.40.190.150 27 312 5.9E-98 T 12-10-2018 MIM_c24590 8c4469b85f04712e503735e6ee60b1b9 119 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 2 119 20.709 T 12-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 MIM_c24590 8c4469b85f04712e503735e6ee60b1b9 119 Gene3D G3DSA:1.20.58.1610 1 119 1.3E-45 T 12-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24590 8c4469b85f04712e503735e6ee60b1b9 119 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 22 118 2.4E-39 T 12-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c27360 7a253e8aeeb380fd86bbe1540ebf25f1 401 Pfam PF13458 Periplasmic binding protein 25 364 3.4E-90 T 12-10-2018 IPR028081 Leucine-binding protein domain MIM_c27360 7a253e8aeeb380fd86bbe1540ebf25f1 401 Gene3D G3DSA:3.40.50.2300 146 277 4.4E-104 T 12-10-2018 MIM_c27360 7a253e8aeeb380fd86bbe1540ebf25f1 401 SUPERFAMILY SSF53822 25 399 3.23E-88 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c27360 7a253e8aeeb380fd86bbe1540ebf25f1 401 Gene3D G3DSA:3.40.50.2300 29 338 4.4E-104 T 12-10-2018 MIM_c20330 7209d13a29b9c804c6c23b7c700cf7d4 298 SUPERFAMILY SSF46785 1 87 1.59E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c20330 7209d13a29b9c804c6c23b7c700cf7d4 298 Gene3D G3DSA:1.10.10.10 1 84 2.8E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c20330 7209d13a29b9c804c6c23b7c700cf7d4 298 Gene3D G3DSA:3.40.190.10 162 267 8.6E-51 T 12-10-2018 MIM_c20330 7209d13a29b9c804c6c23b7c700cf7d4 298 Pfam PF03466 LysR substrate binding domain 87 286 2.0E-35 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c20330 7209d13a29b9c804c6c23b7c700cf7d4 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 3.8E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c20330 7209d13a29b9c804c6c23b7c700cf7d4 298 SUPERFAMILY SSF53850 87 295 4.48E-35 T 12-10-2018 MIM_c20330 7209d13a29b9c804c6c23b7c700cf7d4 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.9E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c20330 7209d13a29b9c804c6c23b7c700cf7d4 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.9E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c20330 7209d13a29b9c804c6c23b7c700cf7d4 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.9E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c20330 7209d13a29b9c804c6c23b7c700cf7d4 298 Gene3D G3DSA:3.40.190.10 88 286 8.6E-51 T 12-10-2018 MIM_c08800 d313b46331f1f3bb95a61a916b656c19 254 Gene3D G3DSA:3.40.50.300 1 253 3.4E-75 T 12-10-2018 MIM_c08800 d313b46331f1f3bb95a61a916b656c19 254 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c08800 d313b46331f1f3bb95a61a916b656c19 254 SMART SM00382 28 226 1.3E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c08800 d313b46331f1f3bb95a61a916b656c19 254 PIRSF PIRSF039085 1 254 1.2E-110 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MIM_c08800 d313b46331f1f3bb95a61a916b656c19 254 Pfam PF00005 ABC transporter 19 178 1.9E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c08800 d313b46331f1f3bb95a61a916b656c19 254 SUPERFAMILY SSF52540 4 247 1.45E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c30590 182a1e68cade8b0c60250e84cbe098af 415 Gene3D G3DSA:3.30.9.10 134 361 2.7E-43 T 12-10-2018 MIM_c30590 182a1e68cade8b0c60250e84cbe098af 415 Gene3D G3DSA:3.50.50.60 1 67 1.3E-10 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c30590 182a1e68cade8b0c60250e84cbe098af 415 Gene3D G3DSA:3.50.50.60 97 399 2.7E-43 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c30590 182a1e68cade8b0c60250e84cbe098af 415 SUPERFAMILY SSF54373 272 362 1.7E-12 T 12-10-2018 MIM_c30590 182a1e68cade8b0c60250e84cbe098af 415 SUPERFAMILY SSF51905 1 408 5.44E-40 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c30590 182a1e68cade8b0c60250e84cbe098af 415 Pfam PF01266 FAD dependent oxidoreductase 2 400 5.9E-59 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MIM_c08370 e3c8c7044d2665bd119c596202f1797b 450 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 66 2.1E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c08370 e3c8c7044d2665bd119c596202f1797b 450 Gene3D G3DSA:1.10.10.10 2 103 1.5E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c08370 e3c8c7044d2665bd119c596202f1797b 450 Gene3D G3DSA:3.40.640.10 131 347 4.2E-68 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c08370 e3c8c7044d2665bd119c596202f1797b 450 SUPERFAMILY SSF46785 3 70 1.52E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c08370 e3c8c7044d2665bd119c596202f1797b 450 Gene3D G3DSA:3.90.1150.10 127 441 4.2E-68 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c08370 e3c8c7044d2665bd119c596202f1797b 450 SUPERFAMILY SSF53383 126 449 9.28E-74 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c08370 e3c8c7044d2665bd119c596202f1797b 450 Pfam PF00155 Aminotransferase class I and II 131 440 4.5E-28 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MIM_c08370 e3c8c7044d2665bd119c596202f1797b 450 SMART SM00345 7 66 1.6E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c22410 07227e1d6733d7a44db49e1fa4388c01 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 249 1.6E-71 T 12-10-2018 MIM_c22410 07227e1d6733d7a44db49e1fa4388c01 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c22410 07227e1d6733d7a44db49e1fa4388c01 257 Gene3D G3DSA:3.40.50.720 5 255 4.1E-87 T 12-10-2018 MIM_c22410 07227e1d6733d7a44db49e1fa4388c01 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.6E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c22410 07227e1d6733d7a44db49e1fa4388c01 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.6E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c22410 07227e1d6733d7a44db49e1fa4388c01 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.6E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c22410 07227e1d6733d7a44db49e1fa4388c01 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.6E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c22410 07227e1d6733d7a44db49e1fa4388c01 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.6E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c22410 07227e1d6733d7a44db49e1fa4388c01 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.6E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c22410 07227e1d6733d7a44db49e1fa4388c01 257 SUPERFAMILY SSF51735 8 251 1.8E-86 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c22410 07227e1d6733d7a44db49e1fa4388c01 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.2E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c22410 07227e1d6733d7a44db49e1fa4388c01 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.2E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c22410 07227e1d6733d7a44db49e1fa4388c01 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.2E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c03490 983098c63283f56067af5936b4b4c812 300 Pfam PF08543 Phosphomethylpyrimidine kinase 49 276 1.1E-22 T 12-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 MIM_c03490 983098c63283f56067af5936b4b4c812 300 TIGRFAM TIGR00687 pyridox_kin: pyridoxal kinase 27 288 1.7E-49 T 12-10-2018 IPR004625 Pyridoxine kinase GO:0008478|GO:0009443 KEGG: 00750+2.7.1.35|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-6798695|Reactome: R-HSA-964975 MIM_c03490 983098c63283f56067af5936b4b4c812 300 SUPERFAMILY SSF53613 28 292 7.79E-60 T 12-10-2018 IPR029056 Ribokinase-like MIM_c03490 983098c63283f56067af5936b4b4c812 300 Gene3D G3DSA:3.40.1190.20 25 294 2.5E-73 T 12-10-2018 IPR029056 Ribokinase-like MIM_c25900 eec3580916e2811a7fc30333c5f7ceff 95 Pfam PF07045 Domain of unknown function (DUF1330) 4 95 3.3E-30 T 12-10-2018 IPR010753 Domain of unknown function DUF1330 MIM_c25900 eec3580916e2811a7fc30333c5f7ceff 95 SUPERFAMILY SSF54909 1 95 2.62E-27 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel MIM_c25900 eec3580916e2811a7fc30333c5f7ceff 95 Gene3D G3DSA:3.30.70.100 1 95 1.3E-29 T 12-10-2018 MIM_c30990 8f6eabbb022e9f2765c5d53a3a2969b5 310 Gene3D G3DSA:3.20.20.370 1 309 1.1E-110 T 12-10-2018 MIM_c30990 8f6eabbb022e9f2765c5d53a3a2969b5 310 TIGRFAM TIGR03212 uraD_N-term-dom: putative urate catabolism protein 7 306 1.9E-155 T 12-10-2018 IPR017625 PuuE allantoinase/chitin deacetylase 1 MIM_c30990 8f6eabbb022e9f2765c5d53a3a2969b5 310 SUPERFAMILY SSF88713 7 307 1.45E-90 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MIM_c30990 8f6eabbb022e9f2765c5d53a3a2969b5 310 Pfam PF01522 Polysaccharide deacetylase 78 166 5.0E-12 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MIM_c16390 9ddb00cd26ef394047f2346cfe333feb 237 SUPERFAMILY SSF55811 75 226 9.04E-34 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MIM_c16390 9ddb00cd26ef394047f2346cfe333feb 237 Pfam PF00293 NUDIX domain 75 157 1.8E-17 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MIM_c16390 9ddb00cd26ef394047f2346cfe333feb 237 Gene3D G3DSA:3.90.79.10 51 232 4.4E-51 T 12-10-2018 MIM_c31320 8908f128ee72c8a8faa4effc1fa0dd23 286 Gene3D G3DSA:3.20.20.60 1 286 3.0E-99 T 12-10-2018 MIM_c31320 8908f128ee72c8a8faa4effc1fa0dd23 286 SUPERFAMILY SSF51621 3 285 6.73E-93 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MIM_c31320 8908f128ee72c8a8faa4effc1fa0dd23 286 Pfam PF13714 Phosphoenolpyruvate phosphomutase 7 248 2.3E-53 T 12-10-2018 MIM_c25620 2fb18a16759e782e9c3507b3530c2ef6 766 Pfam PF00593 TonB dependent receptor 296 765 6.1E-47 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MIM_c25620 2fb18a16759e782e9c3507b3530c2ef6 766 Gene3D G3DSA:2.40.170.20 231 766 2.5E-169 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MIM_c25620 2fb18a16759e782e9c3507b3530c2ef6 766 Pfam PF07715 TonB-dependent Receptor Plug Domain 119 219 4.7E-16 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain MIM_c25620 2fb18a16759e782e9c3507b3530c2ef6 766 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 121 765 1.7E-102 T 12-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 MIM_c25620 2fb18a16759e782e9c3507b3530c2ef6 766 SUPERFAMILY SSF56935 111 766 4.97E-117 T 12-10-2018 MIM_c25620 2fb18a16759e782e9c3507b3530c2ef6 766 Gene3D G3DSA:2.170.130.10 96 228 6.5E-39 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MIM_c12720 34c01b5bb04bf272eb6e433acdbdb23c 330 Gene3D G3DSA:3.40.190.150 35 320 2.1E-118 T 12-10-2018 MIM_c12720 34c01b5bb04bf272eb6e433acdbdb23c 330 Gene3D G3DSA:3.40.190.10 132 255 2.1E-118 T 12-10-2018 MIM_c12720 34c01b5bb04bf272eb6e433acdbdb23c 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 325 2.2E-95 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c12720 34c01b5bb04bf272eb6e433acdbdb23c 330 PIRSF PIRSF017082 1 330 4.4E-93 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c12720 34c01b5bb04bf272eb6e433acdbdb23c 330 SUPERFAMILY SSF53850 118 285 1.18E-14 T 12-10-2018 MIM_c17680 dcc7b89c835eb45e18debc7d9aea5b84 455 SUPERFAMILY SSF55961 160 442 7.06E-55 T 12-10-2018 MIM_c17680 dcc7b89c835eb45e18debc7d9aea5b84 455 Gene3D G3DSA:2.102.10.10 43 172 1.4E-139 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MIM_c17680 dcc7b89c835eb45e18debc7d9aea5b84 455 Gene3D G3DSA:3.90.380.10 18 434 1.4E-139 T 12-10-2018 MIM_c17680 dcc7b89c835eb45e18debc7d9aea5b84 455 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 165 435 1.0E-25 T 12-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 MIM_c17680 dcc7b89c835eb45e18debc7d9aea5b84 455 SUPERFAMILY SSF50022 14 159 4.84E-46 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MIM_c17680 dcc7b89c835eb45e18debc7d9aea5b84 455 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 86 109 - T 12-10-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0051537|GO:0055114 MIM_c17680 dcc7b89c835eb45e18debc7d9aea5b84 455 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 79 99 1.4E-53 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 MIM_c17680 dcc7b89c835eb45e18debc7d9aea5b84 455 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 58 73 1.4E-53 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 MIM_c17680 dcc7b89c835eb45e18debc7d9aea5b84 455 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 28 53 1.4E-53 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 MIM_c17680 dcc7b89c835eb45e18debc7d9aea5b84 455 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 144 170 1.4E-53 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 MIM_c17680 dcc7b89c835eb45e18debc7d9aea5b84 455 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 188 210 1.4E-53 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 MIM_c17680 dcc7b89c835eb45e18debc7d9aea5b84 455 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 100 120 1.4E-53 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 MIM_c17680 dcc7b89c835eb45e18debc7d9aea5b84 455 Pfam PF00355 Rieske [2Fe-2S] domain 44 128 2.1E-19 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MIM_c39370 6f46f4efbb0b0e4ac748e6f83c03d9f9 302 Gene3D G3DSA:2.70.98.10 1 301 3.3E-75 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 MIM_c39370 6f46f4efbb0b0e4ac748e6f83c03d9f9 302 Pfam PF01263 Aldose 1-epimerase 6 296 5.5E-34 T 12-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 MIM_c39370 6f46f4efbb0b0e4ac748e6f83c03d9f9 302 SUPERFAMILY SSF74650 5 299 4.83E-50 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 MIM_c21470 8941a8b09fe92355f0be69fa1df0ea41 127 PIRSF PIRSF000077 1 104 7.7E-28 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MIM_c21470 8941a8b09fe92355f0be69fa1df0ea41 127 Pfam PF00085 Thioredoxin 3 101 7.5E-27 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 MIM_c21470 8941a8b09fe92355f0be69fa1df0ea41 127 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 102 4.3E-30 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MIM_c21470 8941a8b09fe92355f0be69fa1df0ea41 127 SUPERFAMILY SSF52833 2 103 5.07E-34 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c21470 8941a8b09fe92355f0be69fa1df0ea41 127 Gene3D G3DSA:3.40.30.10 1 120 2.5E-31 T 12-10-2018 MIM_c21470 8941a8b09fe92355f0be69fa1df0ea41 127 PRINTS PR00421 Thioredoxin family signature 29 38 4.0E-9 T 12-10-2018 MIM_c21470 8941a8b09fe92355f0be69fa1df0ea41 127 PRINTS PR00421 Thioredoxin family signature 21 29 4.0E-9 T 12-10-2018 MIM_c21470 8941a8b09fe92355f0be69fa1df0ea41 127 PRINTS PR00421 Thioredoxin family signature 68 79 4.0E-9 T 12-10-2018 MIM_c21470 8941a8b09fe92355f0be69fa1df0ea41 127 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MIM_c13020 6b97e1b3c599bfed119e304129569430 314 SUPERFAMILY SSF51735 102 283 1.37E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c13020 6b97e1b3c599bfed119e304129569430 314 Gene3D G3DSA:3.40.50.720 20 305 2.4E-104 T 12-10-2018 MIM_c13020 6b97e1b3c599bfed119e304129569430 314 Gene3D G3DSA:3.40.50.720 101 285 2.4E-104 T 12-10-2018 MIM_c13020 6b97e1b3c599bfed119e304129569430 314 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 20 313 1.2E-21 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 MIM_c13020 6b97e1b3c599bfed119e304129569430 314 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 148 175 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 MIM_c13020 6b97e1b3c599bfed119e304129569430 314 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 282 1.4E-45 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MIM_c13020 6b97e1b3c599bfed119e304129569430 314 SUPERFAMILY SSF52283 4 137 2.08E-27 T 12-10-2018 MIM_c31510 a4ce970b3931d06fca9a4d657892b53c 696 Pfam PF02554 Carbon starvation protein CstA 37 414 1.6E-172 T 12-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 MIM_c31510 a4ce970b3931d06fca9a4d657892b53c 696 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 468 596 3.8E-34 T 12-10-2018 IPR025299 CstA, C-terminal domain MIM_c20860 3c4621dfc8399d0fd081984f29574ad6 259 SUPERFAMILY SSF51735 8 254 1.08E-79 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c20860 3c4621dfc8399d0fd081984f29574ad6 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 251 3.3E-61 T 12-10-2018 MIM_c20860 3c4621dfc8399d0fd081984f29574ad6 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 8.8E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20860 3c4621dfc8399d0fd081984f29574ad6 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 8.8E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20860 3c4621dfc8399d0fd081984f29574ad6 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 8.8E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20860 3c4621dfc8399d0fd081984f29574ad6 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 8.8E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20860 3c4621dfc8399d0fd081984f29574ad6 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 8.8E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20860 3c4621dfc8399d0fd081984f29574ad6 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 8.8E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20860 3c4621dfc8399d0fd081984f29574ad6 259 Gene3D G3DSA:3.40.50.720 1 259 6.2E-79 T 12-10-2018 MIM_c20860 3c4621dfc8399d0fd081984f29574ad6 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 7.1E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20860 3c4621dfc8399d0fd081984f29574ad6 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 7.1E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20860 3c4621dfc8399d0fd081984f29574ad6 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 7.1E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c07210 c8c615a29e30728d9b46de4b7252bbf2 454 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 28 446 5.2E-82 T 12-10-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 MIM_c07210 c8c615a29e30728d9b46de4b7252bbf2 454 SUPERFAMILY SSF53335 159 445 1.08E-68 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c07210 c8c615a29e30728d9b46de4b7252bbf2 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 428 445 8.0E-24 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase MIM_c07210 c8c615a29e30728d9b46de4b7252bbf2 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 271 281 8.0E-24 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase MIM_c07210 c8c615a29e30728d9b46de4b7252bbf2 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 339 351 8.0E-24 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase MIM_c07210 c8c615a29e30728d9b46de4b7252bbf2 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 389 405 8.0E-24 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase MIM_c07210 c8c615a29e30728d9b46de4b7252bbf2 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 242 256 8.0E-24 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase MIM_c07210 c8c615a29e30728d9b46de4b7252bbf2 454 SUPERFAMILY SSF48013 26 171 1.44E-8 T 12-10-2018 IPR035926 NusB-like superfamily MIM_c07210 c8c615a29e30728d9b46de4b7252bbf2 454 Pfam PF01189 16S rRNA methyltransferase RsmB/F 262 419 2.3E-46 T 12-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 MIM_c07210 c8c615a29e30728d9b46de4b7252bbf2 454 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 338 349 - T 12-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 MIM_c07210 c8c615a29e30728d9b46de4b7252bbf2 454 Gene3D G3DSA:3.40.50.150 164 445 4.0E-71 T 12-10-2018 MIM_c07210 c8c615a29e30728d9b46de4b7252bbf2 454 Gene3D G3DSA:1.10.940.10 23 163 5.0E-8 T 12-10-2018 IPR035926 NusB-like superfamily MIM_c30190 a406533d71e3aa881baa952b1e801423 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 21 78 1.4E-12 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c30190 a406533d71e3aa881baa952b1e801423 317 SUPERFAMILY SSF46785 15 95 6.39E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c30190 a406533d71e3aa881baa952b1e801423 317 Gene3D G3DSA:1.10.10.10 11 98 1.3E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c30190 a406533d71e3aa881baa952b1e801423 317 SUPERFAMILY SSF53850 102 306 9.95E-35 T 12-10-2018 MIM_c30190 a406533d71e3aa881baa952b1e801423 317 Pfam PF03466 LysR substrate binding domain 106 306 1.0E-26 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c30190 a406533d71e3aa881baa952b1e801423 317 Gene3D G3DSA:3.40.190.10 102 306 5.8E-41 T 12-10-2018 MIM_c30190 a406533d71e3aa881baa952b1e801423 317 Gene3D G3DSA:3.40.190.10 183 282 5.8E-41 T 12-10-2018 MIM_c06240 3368afc66c1fe3f1c6c7df8dc37627f9 350 SMART SM00342 250 337 4.4E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c06240 3368afc66c1fe3f1c6c7df8dc37627f9 350 Gene3D G3DSA:1.10.10.60 229 344 1.5E-22 T 12-10-2018 MIM_c06240 3368afc66c1fe3f1c6c7df8dc37627f9 350 SUPERFAMILY SSF46689 287 341 1.08E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c06240 3368afc66c1fe3f1c6c7df8dc37627f9 350 Pfam PF12833 Helix-turn-helix domain 256 338 2.7E-17 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c06240 3368afc66c1fe3f1c6c7df8dc37627f9 350 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 288 333 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MIM_c21690 bc19079b2ddc23c3a350027214fc5b06 354 Gene3D G3DSA:1.10.150.20 170 229 1.3E-17 T 12-10-2018 MIM_c21690 bc19079b2ddc23c3a350027214fc5b06 354 Gene3D G3DSA:3.30.1490.100 241 348 7.9E-17 T 12-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MIM_c21690 bc19079b2ddc23c3a350027214fc5b06 354 Hamap MF_01113 DNA polymerase IV [dinB]. 2 353 36.82 T 12-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 MIM_c21690 bc19079b2ddc23c3a350027214fc5b06 354 Pfam PF11799 impB/mucB/samB family C-terminal domain 236 349 1.8E-15 T 12-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MIM_c21690 bc19079b2ddc23c3a350027214fc5b06 354 Pfam PF00817 impB/mucB/samB family 8 154 1.8E-50 T 12-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MIM_c21690 bc19079b2ddc23c3a350027214fc5b06 354 SUPERFAMILY SSF56672 2 234 9.78E-91 T 12-10-2018 MIM_c21690 bc19079b2ddc23c3a350027214fc5b06 354 Gene3D G3DSA:3.30.70.270 70 169 4.7E-38 T 12-10-2018 MIM_c21690 bc19079b2ddc23c3a350027214fc5b06 354 Gene3D G3DSA:2.30.40.20 13 69 1.7E-24 T 12-10-2018 MIM_c21690 bc19079b2ddc23c3a350027214fc5b06 354 Pfam PF11798 IMS family HHH motif 166 195 7.6E-7 T 12-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 MIM_c21690 bc19079b2ddc23c3a350027214fc5b06 354 SUPERFAMILY SSF100879 239 339 1.08E-18 T 12-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MIM_c09800 223029f31b0cca9e1c3cf7bdd85d5a5c 409 Hamap MF_02033 Cell division protein FtsA [ftsA]. 5 407 30.24 T 12-10-2018 IPR020823 Cell division protein FtsA MIM_c09800 223029f31b0cca9e1c3cf7bdd85d5a5c 409 SMART SM00842 9 196 8.6E-104 T 12-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 MIM_c09800 223029f31b0cca9e1c3cf7bdd85d5a5c 409 PIRSF PIRSF003101 1 409 3.8E-146 T 12-10-2018 IPR020823 Cell division protein FtsA MIM_c09800 223029f31b0cca9e1c3cf7bdd85d5a5c 409 SUPERFAMILY SSF53067 198 376 1.47E-45 T 12-10-2018 MIM_c09800 223029f31b0cca9e1c3cf7bdd85d5a5c 409 SUPERFAMILY SSF53067 7 197 7.25E-60 T 12-10-2018 MIM_c09800 223029f31b0cca9e1c3cf7bdd85d5a5c 409 Pfam PF14450 Cell division protein FtsA 10 191 2.0E-10 T 12-10-2018 MIM_c09800 223029f31b0cca9e1c3cf7bdd85d5a5c 409 Gene3D G3DSA:3.30.420.40 12 372 2.0E-119 T 12-10-2018 MIM_c09800 223029f31b0cca9e1c3cf7bdd85d5a5c 409 Gene3D G3DSA:3.90.640.10 235 300 2.0E-119 T 12-10-2018 MIM_c09800 223029f31b0cca9e1c3cf7bdd85d5a5c 409 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 8 377 3.3E-145 T 12-10-2018 IPR020823 Cell division protein FtsA MIM_c09800 223029f31b0cca9e1c3cf7bdd85d5a5c 409 Gene3D G3DSA:3.30.420.40 197 352 2.0E-119 T 12-10-2018 MIM_c09800 223029f31b0cca9e1c3cf7bdd85d5a5c 409 Pfam PF14450 Cell division protein FtsA 207 374 2.9E-24 T 12-10-2018 MIM_c09800 223029f31b0cca9e1c3cf7bdd85d5a5c 409 Pfam PF02491 SHS2 domain inserted in FTSA 85 162 2.8E-31 T 12-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 MIM_c09800 223029f31b0cca9e1c3cf7bdd85d5a5c 409 Gene3D G3DSA:3.30.1490.110 87 169 2.0E-119 T 12-10-2018 MIM_c14770 7eef121961a707d79a538b49248229ab 294 Pfam PF00892 EamA-like transporter family 3 132 3.0E-6 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MIM_c14770 7eef121961a707d79a538b49248229ab 294 SUPERFAMILY SSF103481 37 136 2.62E-10 T 12-10-2018 MIM_c14770 7eef121961a707d79a538b49248229ab 294 SUPERFAMILY SSF103481 198 276 4.84E-6 T 12-10-2018 MIM_c36320 dec155214c6a8ec48c2053abb39ff710 229 Pfam PF01965 DJ-1/PfpI family 25 220 6.2E-14 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 MIM_c36320 dec155214c6a8ec48c2053abb39ff710 229 Gene3D G3DSA:3.40.50.880 1 223 1.5E-80 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c36320 dec155214c6a8ec48c2053abb39ff710 229 SUPERFAMILY SSF52317 1 221 1.27E-74 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c40750 1aa9fcb763ab2a6cd170f2aa0a6e2de0 307 Pfam PF02195 ParB-like nuclease domain 46 138 8.3E-25 T 12-10-2018 IPR003115 ParB/Sulfiredoxin MIM_c40750 1aa9fcb763ab2a6cd170f2aa0a6e2de0 307 SUPERFAMILY SSF110849 46 140 6.28E-27 T 12-10-2018 IPR036086 ParB/Sulfiredoxin superfamily MIM_c40750 1aa9fcb763ab2a6cd170f2aa0a6e2de0 307 Gene3D G3DSA:3.90.1530.30 58 124 4.0E-27 T 12-10-2018 MIM_c40750 1aa9fcb763ab2a6cd170f2aa0a6e2de0 307 SMART SM00470 45 138 1.6E-35 T 12-10-2018 IPR003115 ParB/Sulfiredoxin MIM_c40750 1aa9fcb763ab2a6cd170f2aa0a6e2de0 307 SUPERFAMILY SSF109709 131 238 5.23E-33 T 12-10-2018 MIM_c40750 1aa9fcb763ab2a6cd170f2aa0a6e2de0 307 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 45 214 1.3E-57 T 12-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 MIM_c40750 1aa9fcb763ab2a6cd170f2aa0a6e2de0 307 Gene3D G3DSA:1.10.10.2830 125 238 1.6E-34 T 12-10-2018 MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 Gene3D G3DSA:1.20.1060.10 521 636 1.1E-41 T 12-10-2018 MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 TIGRFAM TIGR00593 pola: DNA polymerase I 5 905 1.6E-270 T 12-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 SMART SM00475 2 256 9.3E-112 T 12-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 Gene3D G3DSA:1.10.150.20 687 829 2.9E-104 T 12-10-2018 MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 SMART SM00279 169 204 8.7E-12 T 12-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 ProSitePatterns PS00447 DNA polymerase family A signature. 732 751 - T 12-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 SUPERFAMILY SSF53098 309 496 1.24E-50 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 SUPERFAMILY SSF56672 505 905 2.89E-148 T 12-10-2018 MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 SMART SM00474 310 496 2.0E-30 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 Gene3D G3DSA:1.10.150.20 170 242 4.8E-88 T 12-10-2018 MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 Pfam PF00476 DNA polymerase family A 529 903 9.9E-148 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 SUPERFAMILY SSF88723 1 166 1.23E-54 T 12-10-2018 IPR029060 PIN-like domain superfamily MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 167 249 4.1E-24 T 12-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 732 757 2.4E-76 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 791 802 2.4E-76 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 633 655 2.4E-76 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 769 780 2.4E-76 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 678 701 2.4E-76 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 852 865 2.4E-76 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 708 721 2.4E-76 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 822 838 2.4E-76 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 656 671 2.4E-76 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 SMART SM00482 664 869 3.4E-112 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 SUPERFAMILY SSF47807 167 283 5.38E-31 T 12-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 5 166 1.5E-51 T 12-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 Gene3D G3DSA:3.30.70.370 644 901 2.9E-104 T 12-10-2018 MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 Gene3D G3DSA:3.40.50.1010 5 276 4.8E-88 T 12-10-2018 MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 Pfam PF01612 3'-5' exonuclease 310 495 6.6E-37 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MIM_c14740 332569b46bb4eb5c0c50711f4af6b749 905 Gene3D G3DSA:3.30.420.10 307 520 2.0E-63 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MIM_c01810 44cf76940a202524dc19e121e0e1a30e 373 Pfam PF01497 Periplasmic binding protein 72 315 6.7E-19 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain MIM_c01810 44cf76940a202524dc19e121e0e1a30e 373 SUPERFAMILY SSF53807 32 359 4.71E-35 T 12-10-2018 MIM_c01810 44cf76940a202524dc19e121e0e1a30e 373 Gene3D G3DSA:3.40.50.1980 28 366 7.1E-70 T 12-10-2018 MIM_c24960 32a98950dcb931a7ff5d13b719acad4f 252 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 239 1.9E-40 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c24960 32a98950dcb931a7ff5d13b719acad4f 252 SUPERFAMILY SSF52096 3 246 3.45E-64 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c24960 32a98950dcb931a7ff5d13b719acad4f 252 Gene3D G3DSA:3.90.226.10 1 250 4.5E-63 T 12-10-2018 MIM_c35940 30ed08c97509bcef0e76e66e266ef7a2 352 Pfam PF08402 TOBE domain 279 344 3.4E-10 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 MIM_c35940 30ed08c97509bcef0e76e66e266ef7a2 352 SUPERFAMILY SSF52540 8 246 6.36E-79 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c35940 30ed08c97509bcef0e76e66e266ef7a2 352 Gene3D G3DSA:3.40.50.300 7 273 2.5E-74 T 12-10-2018 MIM_c35940 30ed08c97509bcef0e76e66e266ef7a2 352 SUPERFAMILY SSF50331 254 345 2.86E-9 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MIM_c35940 30ed08c97509bcef0e76e66e266ef7a2 352 Pfam PF00005 ABC transporter 24 168 3.8E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c35940 30ed08c97509bcef0e76e66e266ef7a2 352 SMART SM00382 33 225 1.2E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c35940 30ed08c97509bcef0e76e66e266ef7a2 352 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c24800 9893065a7a4aef7f6ecd8ad655eaf6c6 303 Gene3D G3DSA:3.40.190.10 91 280 9.4E-32 T 12-10-2018 MIM_c24800 9893065a7a4aef7f6ecd8ad655eaf6c6 303 Gene3D G3DSA:1.10.10.10 1 90 2.7E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c24800 9893065a7a4aef7f6ecd8ad655eaf6c6 303 SUPERFAMILY SSF46785 1 111 9.33E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c24800 9893065a7a4aef7f6ecd8ad655eaf6c6 303 Gene3D G3DSA:3.40.190.10 164 267 9.4E-32 T 12-10-2018 MIM_c24800 9893065a7a4aef7f6ecd8ad655eaf6c6 303 SUPERFAMILY SSF53850 89 290 1.02E-32 T 12-10-2018 MIM_c24800 9893065a7a4aef7f6ecd8ad655eaf6c6 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 7.9E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c24800 9893065a7a4aef7f6ecd8ad655eaf6c6 303 Pfam PF03466 LysR substrate binding domain 89 288 7.4E-30 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c21280 77a7815e8b8fe22c2277774e005845f3 323 SUPERFAMILY SSF53822 35 284 2.67E-20 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c21280 77a7815e8b8fe22c2277774e005845f3 323 Pfam PF04392 ABC transporter substrate binding protein 31 321 2.4E-111 T 12-10-2018 IPR007487 ABC transporter, substrate-binding protein MIM_c21280 77a7815e8b8fe22c2277774e005845f3 323 Gene3D G3DSA:3.40.50.2300 144 314 8.0E-92 T 12-10-2018 MIM_c21280 77a7815e8b8fe22c2277774e005845f3 323 Gene3D G3DSA:3.40.50.2300 47 293 8.0E-92 T 12-10-2018 MIM_c19390 84a0c44df04d2c1aa837cbd96ad99556 390 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 385 44.975 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MIM_c19390 84a0c44df04d2c1aa837cbd96ad99556 390 PIRSF PIRSF006205 1 390 3.6E-150 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MIM_c19390 84a0c44df04d2c1aa837cbd96ad99556 390 SUPERFAMILY SSF55347 126 263 1.21E-61 T 12-10-2018 MIM_c19390 84a0c44df04d2c1aa837cbd96ad99556 390 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 132 7.6E-41 T 12-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MIM_c19390 84a0c44df04d2c1aa837cbd96ad99556 390 Gene3D G3DSA:1.10.1740.10 303 388 8.9E-26 T 12-10-2018 MIM_c19390 84a0c44df04d2c1aa837cbd96ad99556 390 Gene3D G3DSA:3.40.50.720 1 150 2.4E-50 T 12-10-2018 MIM_c19390 84a0c44df04d2c1aa837cbd96ad99556 390 Pfam PF13288 DXP reductoisomerase C-terminal domain 262 380 4.7E-36 T 12-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MIM_c19390 84a0c44df04d2c1aa837cbd96ad99556 390 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 383 1.5E-150 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MIM_c19390 84a0c44df04d2c1aa837cbd96ad99556 390 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 146 230 2.9E-41 T 12-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MIM_c19390 84a0c44df04d2c1aa837cbd96ad99556 390 SUPERFAMILY SSF51735 2 150 3.86E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c19390 84a0c44df04d2c1aa837cbd96ad99556 390 SUPERFAMILY SSF69055 292 386 7.46E-26 T 12-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MIM_c16950 90dd0c4635986a153ea21940da7d3432 391 Pfam PF13609 Gram-negative porin 10 363 3.7E-48 T 12-10-2018 MIM_c16950 90dd0c4635986a153ea21940da7d3432 391 SUPERFAMILY SSF56935 21 391 5.19E-60 T 12-10-2018 MIM_c16950 90dd0c4635986a153ea21940da7d3432 391 Gene3D G3DSA:2.40.160.10 10 391 6.8E-75 T 12-10-2018 IPR023614 Porin domain superfamily MIM_c16950 90dd0c4635986a153ea21940da7d3432 391 PRINTS PR00184 Neisseria sp. porin signature 161 178 1.3E-6 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 MIM_c16950 90dd0c4635986a153ea21940da7d3432 391 PRINTS PR00184 Neisseria sp. porin signature 60 85 1.3E-6 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 MIM_c16950 90dd0c4635986a153ea21940da7d3432 391 PRINTS PR00184 Neisseria sp. porin signature 339 363 1.3E-6 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 MIM_c06910 8da3f63887669c3afcb51ea30d63bf3d 1230 Pfam PF00534 Glycosyl transferases group 1 225 374 8.6E-30 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 MIM_c06910 8da3f63887669c3afcb51ea30d63bf3d 1230 Pfam PF00534 Glycosyl transferases group 1 635 768 2.9E-13 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 MIM_c06910 8da3f63887669c3afcb51ea30d63bf3d 1230 SUPERFAMILY SSF53756 15 403 9.42E-56 T 12-10-2018 MIM_c06910 8da3f63887669c3afcb51ea30d63bf3d 1230 Gene3D G3DSA:3.40.50.2000 626 836 7.4E-41 T 12-10-2018 MIM_c06910 8da3f63887669c3afcb51ea30d63bf3d 1230 Gene3D G3DSA:3.40.50.2000 201 384 1.6E-47 T 12-10-2018 MIM_c06910 8da3f63887669c3afcb51ea30d63bf3d 1230 SUPERFAMILY SSF53756 847 1209 1.26E-23 T 12-10-2018 MIM_c06910 8da3f63887669c3afcb51ea30d63bf3d 1230 Gene3D G3DSA:3.40.50.2000 16 396 1.6E-47 T 12-10-2018 MIM_c06910 8da3f63887669c3afcb51ea30d63bf3d 1230 SUPERFAMILY SSF53756 489 834 4.71E-35 T 12-10-2018 MIM_c06910 8da3f63887669c3afcb51ea30d63bf3d 1230 Gene3D G3DSA:3.40.50.2000 996 1195 4.8E-14 T 12-10-2018 MIM_c05950 cf0d59de18a29ecac718cad335db67a2 214 Gene3D G3DSA:3.10.180.10 6 149 1.9E-9 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c05950 cf0d59de18a29ecac718cad335db67a2 214 SUPERFAMILY SSF54593 6 75 1.84E-5 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c05950 cf0d59de18a29ecac718cad335db67a2 214 Pfam PF13468 Glyoxalase-like domain 8 181 5.9E-42 T 12-10-2018 IPR025870 Glyoxalase-like domain MIM_c14760 537d65afeb394d95109e6d9afb9df056 294 Pfam PF01435 Peptidase family M48 81 290 5.6E-39 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 MIM_c14760 537d65afeb394d95109e6d9afb9df056 294 Hamap MF_00188 Protease HtpX [htpX]. 1 290 24.878 T 12-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 MIM_c14760 537d65afeb394d95109e6d9afb9df056 294 Gene3D G3DSA:3.30.2010.10 74 164 3.3E-29 T 12-10-2018 MIM_c11880 9a151cf7a226ee4cb9db8effb8d6d340 164 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 6.0E-34 T 12-10-2018 MIM_c11880 9a151cf7a226ee4cb9db8effb8d6d340 164 Gene3D G3DSA:3.30.70.260 1 78 3.7E-34 T 12-10-2018 MIM_c11880 9a151cf7a226ee4cb9db8effb8d6d340 164 Pfam PF10369 Small subunit of acetolactate synthase 84 157 9.6E-28 T 12-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MIM_c11880 9a151cf7a226ee4cb9db8effb8d6d340 164 Pfam PF13710 ACT domain 12 73 1.8E-15 T 12-10-2018 MIM_c11880 9a151cf7a226ee4cb9db8effb8d6d340 164 Gene3D G3DSA:3.30.70.1150 83 163 2.1E-30 T 12-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal MIM_c11880 9a151cf7a226ee4cb9db8effb8d6d340 164 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 157 1.1E-63 T 12-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MIM_c11880 9a151cf7a226ee4cb9db8effb8d6d340 164 SUPERFAMILY SSF55021 79 162 6.41E-26 T 12-10-2018 MIM_c11880 9a151cf7a226ee4cb9db8effb8d6d340 164 SUPERFAMILY SSF55021 1 76 1.15E-21 T 12-10-2018 MIM_c31920 a21fec4274f87689777fcd25bbb213d6 1088 Pfam PF04851 Type III restriction enzyme, res subunit 138 307 1.1E-18 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MIM_c31920 a21fec4274f87689777fcd25bbb213d6 1088 SUPERFAMILY SSF52540 163 469 7.79E-29 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c31920 a21fec4274f87689777fcd25bbb213d6 1088 SMART SM00490 384 467 3.5E-5 T 12-10-2018 IPR001650 Helicase, C-terminal MIM_c31920 a21fec4274f87689777fcd25bbb213d6 1088 Gene3D G3DSA:3.40.50.300 337 492 5.9E-14 T 12-10-2018 MIM_c31920 a21fec4274f87689777fcd25bbb213d6 1088 Gene3D G3DSA:3.40.50.300 129 328 3.9E-22 T 12-10-2018 MIM_c31920 a21fec4274f87689777fcd25bbb213d6 1088 Pfam PF00271 Helicase conserved C-terminal domain 382 466 8.2E-6 T 12-10-2018 IPR001650 Helicase, C-terminal MIM_c31920 a21fec4274f87689777fcd25bbb213d6 1088 SMART SM00487 134 344 1.2E-12 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MIM_c24360 791df8a5d9010459d3da06daa2463f17 182 PIRSF PIRSF000239 1 182 8.1E-38 T 12-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MIM_c24360 791df8a5d9010459d3da06daa2463f17 182 Gene3D G3DSA:3.40.30.10 8 182 2.8E-46 T 12-10-2018 MIM_c24360 791df8a5d9010459d3da06daa2463f17 182 Pfam PF00578 AhpC/TSA family 30 143 1.3E-23 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MIM_c24360 791df8a5d9010459d3da06daa2463f17 182 SUPERFAMILY SSF52833 31 181 9.17E-43 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c18750 3c86501bba3fe9afbd6a5dbee7333f20 236 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c18750 3c86501bba3fe9afbd6a5dbee7333f20 236 SMART SM00382 44 232 1.9E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c18750 3c86501bba3fe9afbd6a5dbee7333f20 236 TIGRFAM TIGR02211 LolD_lipo_ex: lipoprotein releasing system, ATP-binding protein 16 234 9.0E-95 T 12-10-2018 IPR011924 Lipoprotein releasing system, ATP-binding protein GO:0005524|GO:0016020|GO:0044873 MIM_c18750 3c86501bba3fe9afbd6a5dbee7333f20 236 Pfam PF00005 ABC transporter 35 183 1.0E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c18750 3c86501bba3fe9afbd6a5dbee7333f20 236 SUPERFAMILY SSF52540 16 233 4.9E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c18750 3c86501bba3fe9afbd6a5dbee7333f20 236 Gene3D G3DSA:3.40.50.300 14 236 3.4E-65 T 12-10-2018 MIM_c39760 17e354e1036c8456700fcbed9b1a12aa 311 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 8 304 5.2E-94 T 12-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 MIM_c39760 17e354e1036c8456700fcbed9b1a12aa 311 Gene3D G3DSA:3.40.1190.20 1 310 2.5E-95 T 12-10-2018 IPR029056 Ribokinase-like MIM_c39760 17e354e1036c8456700fcbed9b1a12aa 311 Pfam PF00294 pfkB family carbohydrate kinase 7 299 2.6E-64 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB MIM_c39760 17e354e1036c8456700fcbed9b1a12aa 311 SUPERFAMILY SSF53613 6 306 1.53E-78 T 12-10-2018 IPR029056 Ribokinase-like MIM_c39760 17e354e1036c8456700fcbed9b1a12aa 311 PRINTS PR00990 Ribokinase signature 109 122 1.1E-27 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MIM_c39760 17e354e1036c8456700fcbed9b1a12aa 311 PRINTS PR00990 Ribokinase signature 177 192 1.1E-27 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MIM_c39760 17e354e1036c8456700fcbed9b1a12aa 311 PRINTS PR00990 Ribokinase signature 37 56 1.1E-27 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MIM_c39760 17e354e1036c8456700fcbed9b1a12aa 311 PRINTS PR00990 Ribokinase signature 221 232 1.1E-27 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MIM_c39760 17e354e1036c8456700fcbed9b1a12aa 311 PRINTS PR00990 Ribokinase signature 10 31 1.1E-27 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MIM_c39760 17e354e1036c8456700fcbed9b1a12aa 311 Hamap MF_01987 Ribokinase [rbsK]. 6 306 24.488 T 12-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 MIM_c39760 17e354e1036c8456700fcbed9b1a12aa 311 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 251 264 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MIM_c38910 962a47d06beb28c935c04fbe39462dbe 414 Gene3D G3DSA:1.20.1250.20 227 411 1.4E-29 T 12-10-2018 MIM_c38910 962a47d06beb28c935c04fbe39462dbe 414 SUPERFAMILY SSF103473 16 414 1.96E-77 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c38910 962a47d06beb28c935c04fbe39462dbe 414 Gene3D G3DSA:1.20.1250.20 22 211 2.4E-35 T 12-10-2018 MIM_c38910 962a47d06beb28c935c04fbe39462dbe 414 Pfam PF07690 Major Facilitator Superfamily 30 278 4.5E-32 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c38910 962a47d06beb28c935c04fbe39462dbe 414 ProSitePatterns PS00217 Sugar transport proteins signature 2. 120 145 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MIM_c19550 4a1825363e98ade8b6a6590eb51f0e0f 153 Pfam PF01668 SmpB protein 3 146 1.1E-58 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 MIM_c19550 4a1825363e98ade8b6a6590eb51f0e0f 153 TIGRFAM TIGR00086 smpB: SsrA-binding protein 3 145 9.4E-54 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 MIM_c19550 4a1825363e98ade8b6a6590eb51f0e0f 153 Gene3D G3DSA:2.40.280.10 1 124 2.0E-47 T 12-10-2018 IPR023620 Small protein B MIM_c19550 4a1825363e98ade8b6a6590eb51f0e0f 153 ProSitePatterns PS01317 SsrA-binding protein. 21 33 - T 12-10-2018 IPR020081 SsrA-binding protein, conserved site MIM_c19550 4a1825363e98ade8b6a6590eb51f0e0f 153 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 3 110 1.0E-45 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 MIM_c19550 4a1825363e98ade8b6a6590eb51f0e0f 153 SUPERFAMILY SSF74982 3 127 3.4E-49 T 12-10-2018 IPR023620 Small protein B MIM_c19550 4a1825363e98ade8b6a6590eb51f0e0f 153 Hamap MF_00023 SsrA-binding protein [smpB]. 1 150 71.067 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 MIM_c26790 ae348354e667e2e04a571784f5a5f5c5 298 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 189 288 1.2E-29 T 12-10-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 MIM_c26790 ae348354e667e2e04a571784f5a5f5c5 298 Gene3D G3DSA:2.160.20.70 184 295 7.0E-31 T 12-10-2018 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 MIM_c26790 ae348354e667e2e04a571784f5a5f5c5 298 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 10 288 5.9E-51 T 12-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 MIM_c26790 ae348354e667e2e04a571784f5a5f5c5 298 Gene3D G3DSA:3.30.750.120 3 116 2.4E-22 T 12-10-2018 IPR038061 MinC, Proteobacteria, N-terminal domain superfamily MIM_c26790 ae348354e667e2e04a571784f5a5f5c5 298 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 9 293 25.31 T 12-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 MIM_c26790 ae348354e667e2e04a571784f5a5f5c5 298 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 9 98 8.0E-14 T 12-10-2018 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 MIM_c26790 ae348354e667e2e04a571784f5a5f5c5 298 SUPERFAMILY SSF63848 186 289 7.32E-28 T 12-10-2018 IPR036145 Septum formation inhibitor MinC, C-terminal domain superfamily GO:0000902 MIM_c24870 ec2329cb41bf4007ff71437530a1022c 752 Gene3D G3DSA:2.40.170.20 202 752 9.9E-133 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MIM_c24870 ec2329cb41bf4007ff71437530a1022c 752 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 92 752 6.7E-93 T 12-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 MIM_c24870 ec2329cb41bf4007ff71437530a1022c 752 Gene3D G3DSA:2.170.130.10 72 201 2.1E-42 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MIM_c24870 ec2329cb41bf4007ff71437530a1022c 752 SUPERFAMILY SSF56935 73 752 1.3E-127 T 12-10-2018 MIM_c24870 ec2329cb41bf4007ff71437530a1022c 752 Pfam PF07715 TonB-dependent Receptor Plug Domain 90 188 1.1E-18 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain MIM_c24870 ec2329cb41bf4007ff71437530a1022c 752 Pfam PF00593 TonB dependent receptor 263 751 6.2E-56 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MIM_c22950 f4a417868885a4bb71774cf408a8056c 392 SUPERFAMILY SSF111369 55 279 5.75E-24 T 12-10-2018 MIM_c22950 f4a417868885a4bb71774cf408a8056c 392 Gene3D G3DSA:1.10.287.470 99 167 4.4E-69 T 12-10-2018 MIM_c22950 f4a417868885a4bb71774cf408a8056c 392 Gene3D G3DSA:2.40.50.100 64 205 4.4E-69 T 12-10-2018 MIM_c22950 f4a417868885a4bb71774cf408a8056c 392 Gene3D G3DSA:2.40.420.20 40 341 4.4E-69 T 12-10-2018 MIM_c22950 f4a417868885a4bb71774cf408a8056c 392 Gene3D G3DSA:2.40.30.170 52 282 4.4E-69 T 12-10-2018 MIM_c22950 f4a417868885a4bb71774cf408a8056c 392 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 65 275 4.9E-19 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MIM_c22950 f4a417868885a4bb71774cf408a8056c 392 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 39 356 6.4E-69 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MIM_c38010 0067d98f539f884493facfb322a1c07f 520 Pfam PF07690 Major Facilitator Superfamily 29 422 2.5E-50 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c38010 0067d98f539f884493facfb322a1c07f 520 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 24 503 7.7E-150 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 MIM_c38010 0067d98f539f884493facfb322a1c07f 520 Gene3D G3DSA:1.20.1720.10 26 211 1.9E-45 T 12-10-2018 MIM_c38010 0067d98f539f884493facfb322a1c07f 520 SUPERFAMILY SSF103473 11 506 1.26E-65 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c38010 0067d98f539f884493facfb322a1c07f 520 PRINTS PR01036 Tetracycline resistance protein TetB signature 149 173 6.8E-5 T 12-10-2018 MIM_c38010 0067d98f539f884493facfb322a1c07f 520 PRINTS PR01036 Tetracycline resistance protein TetB signature 28 52 6.8E-5 T 12-10-2018 MIM_c38010 0067d98f539f884493facfb322a1c07f 520 Gene3D G3DSA:1.20.1250.20 269 506 3.6E-11 T 12-10-2018 MIM_c29070 8a0f46a6937cb78da4c229902f203a40 167 Gene3D G3DSA:3.90.960.10 4 167 3.1E-44 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 MIM_c29070 8a0f46a6937cb78da4c229902f203a40 167 Pfam PF04073 Aminoacyl-tRNA editing domain 24 150 1.9E-22 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MIM_c29070 8a0f46a6937cb78da4c229902f203a40 167 SUPERFAMILY SSF55826 3 163 8.11E-40 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 MIM_c09330 a5fa09176d57d755d789da882bd9b47e 242 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c09330 a5fa09176d57d755d789da882bd9b47e 242 SMART SM00382 28 215 1.3E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c09330 a5fa09176d57d755d789da882bd9b47e 242 Pfam PF00005 ABC transporter 19 167 5.0E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c09330 a5fa09176d57d755d789da882bd9b47e 242 SUPERFAMILY SSF52540 3 237 1.73E-77 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c09330 a5fa09176d57d755d789da882bd9b47e 242 PIRSF PIRSF039085 1 242 8.4E-107 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MIM_c09330 a5fa09176d57d755d789da882bd9b47e 242 Gene3D G3DSA:3.40.50.300 2 242 5.0E-77 T 12-10-2018 MIM_c08180 2649c60a2fd739ce817a70424d9b34ae 179 Gene3D G3DSA:3.10.180.10 3 145 7.2E-32 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c08180 2649c60a2fd739ce817a70424d9b34ae 179 SUPERFAMILY SSF54593 8 146 3.16E-17 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c08180 2649c60a2fd739ce817a70424d9b34ae 179 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 131 6.6E-31 T 12-10-2018 MIM_c16340 8cc0323608b0c0a3ac6eeb86ac8e9495 326 PIRSF PIRSF017082 1 326 3.0E-82 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c16340 8cc0323608b0c0a3ac6eeb86ac8e9495 326 Gene3D G3DSA:3.40.190.150 29 316 2.0E-112 T 12-10-2018 MIM_c16340 8cc0323608b0c0a3ac6eeb86ac8e9495 326 Gene3D G3DSA:3.40.190.10 127 250 2.0E-112 T 12-10-2018 MIM_c16340 8cc0323608b0c0a3ac6eeb86ac8e9495 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 321 4.1E-88 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c16340 8cc0323608b0c0a3ac6eeb86ac8e9495 326 SUPERFAMILY SSF53850 108 286 6.67E-11 T 12-10-2018 MIM_c07360 f49071c8bf330a3de9f66ecd732dbca1 178 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 16 151 4.5E-44 T 12-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MIM_c07360 f49071c8bf330a3de9f66ecd732dbca1 178 Hamap MF_00821 Protein-export protein SecB [secB]. 1 154 31.018 T 12-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MIM_c07360 f49071c8bf330a3de9f66ecd732dbca1 178 Gene3D G3DSA:3.10.420.10 1 165 9.5E-51 T 12-10-2018 IPR035958 SecB-like superfamily MIM_c07360 f49071c8bf330a3de9f66ecd732dbca1 178 SUPERFAMILY SSF54611 18 158 6.1E-47 T 12-10-2018 IPR035958 SecB-like superfamily MIM_c07360 f49071c8bf330a3de9f66ecd732dbca1 178 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 82 102 1.5E-27 T 12-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MIM_c07360 f49071c8bf330a3de9f66ecd732dbca1 178 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 132 150 1.5E-27 T 12-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MIM_c07360 f49071c8bf330a3de9f66ecd732dbca1 178 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 106 128 1.5E-27 T 12-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MIM_c07360 f49071c8bf330a3de9f66ecd732dbca1 178 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 22 39 1.5E-27 T 12-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MIM_c07360 f49071c8bf330a3de9f66ecd732dbca1 178 Pfam PF02556 Preprotein translocase subunit SecB 15 152 9.6E-52 T 12-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MIM_c15980 e99e98d899b41b8acbd270b9a14f2175 172 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 12 166 16.596 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MIM_c15980 e99e98d899b41b8acbd270b9a14f2175 172 Pfam PF01252 Signal peptidase (SPase) II 21 160 5.2E-38 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MIM_c15980 e99e98d899b41b8acbd270b9a14f2175 172 TIGRFAM TIGR00077 lspA: signal peptidase II 13 165 1.2E-40 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MIM_c15980 e99e98d899b41b8acbd270b9a14f2175 172 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 105 120 3.6E-18 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MIM_c15980 e99e98d899b41b8acbd270b9a14f2175 172 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 58 66 3.6E-18 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MIM_c15980 e99e98d899b41b8acbd270b9a14f2175 172 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 141 157 3.6E-18 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MIM_c07850 8c793c30f661de1e4e6bc5c8760e9692 305 SUPERFAMILY SSF51569 4 298 3.77E-67 T 12-10-2018 MIM_c07850 8c793c30f661de1e4e6bc5c8760e9692 305 SMART SM01130 4 297 4.4E-72 T 12-10-2018 IPR002220 DapA-like GO:0016829 MIM_c07850 8c793c30f661de1e4e6bc5c8760e9692 305 Pfam PF00701 Dihydrodipicolinate synthetase family 5 295 1.0E-42 T 12-10-2018 IPR002220 DapA-like GO:0016829 MIM_c07850 8c793c30f661de1e4e6bc5c8760e9692 305 Gene3D G3DSA:3.20.20.70 3 297 1.6E-83 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c07850 8c793c30f661de1e4e6bc5c8760e9692 305 PIRSF PIRSF001365 1 303 1.9E-54 T 12-10-2018 IPR002220 DapA-like GO:0016829 MIM_c32030 df1509ca6c42e1688a7646fe74c50a5a 344 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 304 319 4.1E-7 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MIM_c32030 df1509ca6c42e1688a7646fe74c50a5a 344 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 319 335 4.1E-7 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MIM_c32030 df1509ca6c42e1688a7646fe74c50a5a 344 Pfam PF12833 Helix-turn-helix domain 256 335 2.9E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c32030 df1509ca6c42e1688a7646fe74c50a5a 344 SUPERFAMILY SSF51182 86 154 7.41E-6 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c32030 df1509ca6c42e1688a7646fe74c50a5a 344 SUPERFAMILY SSF46689 286 337 6.72E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c32030 df1509ca6c42e1688a7646fe74c50a5a 344 SMART SM00342 250 335 1.5E-23 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c32030 df1509ca6c42e1688a7646fe74c50a5a 344 Gene3D G3DSA:1.10.10.60 229 341 4.2E-27 T 12-10-2018 MIM_c32030 df1509ca6c42e1688a7646fe74c50a5a 344 Pfam PF14525 AraC-binding-like domain 98 214 2.3E-17 T 12-10-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like MIM_c09000 d964c4174b0282a7251aeeae30fde1fa 223 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 13 195 3.2E-58 T 12-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MIM_c09000 d964c4174b0282a7251aeeae30fde1fa 223 SUPERFAMILY SSF53271 8 220 3.02E-46 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like MIM_c09000 d964c4174b0282a7251aeeae30fde1fa 223 Gene3D G3DSA:3.40.50.2020 4 221 1.6E-68 T 12-10-2018 MIM_c09000 d964c4174b0282a7251aeeae30fde1fa 223 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 223 33.38 T 12-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MIM_c09000 d964c4174b0282a7251aeeae30fde1fa 223 Pfam PF00156 Phosphoribosyl transferase domain 41 168 7.0E-15 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MIM_c23310 b2cb907f3570c22be1f59d81c2076680 245 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 235 5.8E-91 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c23310 b2cb907f3570c22be1f59d81c2076680 245 Gene3D G3DSA:3.30.70.980 86 235 3.1E-50 T 12-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c23310 b2cb907f3570c22be1f59d81c2076680 245 Pfam PF01709 Transcriptional regulator 5 236 6.7E-94 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c23310 b2cb907f3570c22be1f59d81c2076680 245 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 239 34.48 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c23310 b2cb907f3570c22be1f59d81c2076680 245 Gene3D G3DSA:3.30.70.980 130 205 3.1E-50 T 12-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c23310 b2cb907f3570c22be1f59d81c2076680 245 Gene3D G3DSA:1.10.10.200 1 81 8.2E-35 T 12-10-2018 IPR017856 Integrase-like, N-terminal MIM_c23310 b2cb907f3570c22be1f59d81c2076680 245 SUPERFAMILY SSF75625 3 241 1.2E-93 T 12-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c38780 a761ac2ada5c6575ac68fa0c19653705 207 Pfam PF01926 50S ribosome-binding GTPase 26 151 8.8E-18 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 MIM_c38780 a761ac2ada5c6575ac68fa0c19653705 207 Gene3D G3DSA:3.40.50.300 1 205 4.0E-51 T 12-10-2018 MIM_c38780 a761ac2ada5c6575ac68fa0c19653705 207 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 7 197 3.1E-60 T 12-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 MIM_c38780 a761ac2ada5c6575ac68fa0c19653705 207 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 12 201 26.045 T 12-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 MIM_c38780 a761ac2ada5c6575ac68fa0c19653705 207 SUPERFAMILY SSF52540 7 201 1.05E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c28450 ee8b5f4f1a77840403012f9493b12ded 175 Gene3D G3DSA:3.30.70.640 18 175 2.2E-61 T 12-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MIM_c28450 ee8b5f4f1a77840403012f9493b12ded 175 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 21 169 4.5E-54 T 12-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MIM_c28450 ee8b5f4f1a77840403012f9493b12ded 175 Pfam PF01967 MoaC family 32 167 3.4E-48 T 12-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MIM_c28450 ee8b5f4f1a77840403012f9493b12ded 175 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 19 175 33.175 T 12-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MIM_c28450 ee8b5f4f1a77840403012f9493b12ded 175 SUPERFAMILY SSF55040 28 172 3.01E-54 T 12-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MIM_c13730 04f14108c8b839372175c554470ec324 446 Gene3D G3DSA:1.20.1250.20 33 428 6.5E-14 T 12-10-2018 MIM_c13730 04f14108c8b839372175c554470ec324 446 Pfam PF07690 Major Facilitator Superfamily 43 340 3.6E-9 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c13730 04f14108c8b839372175c554470ec324 446 SUPERFAMILY SSF103473 33 434 4.19E-25 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c16530 226ddda1378f9cd9796a1aa4d3a6d75e 243 Pfam PF01435 Peptidase family M48 90 242 9.8E-27 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 MIM_c16530 226ddda1378f9cd9796a1aa4d3a6d75e 243 Gene3D G3DSA:3.30.2010.10 60 143 3.2E-7 T 12-10-2018 MIM_c36810 c37a4afdfd797a41ec7ce9461f83efe9 240 SMART SM00345 11 70 5.0E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c36810 c37a4afdfd797a41ec7ce9461f83efe9 240 SMART SM00895 100 222 7.6E-25 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c36810 c37a4afdfd797a41ec7ce9461f83efe9 240 SUPERFAMILY SSF48008 97 228 1.33E-28 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c36810 c37a4afdfd797a41ec7ce9461f83efe9 240 Pfam PF07729 FCD domain 100 221 1.1E-25 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c36810 c37a4afdfd797a41ec7ce9461f83efe9 240 Gene3D G3DSA:1.10.10.10 2 76 5.5E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c36810 c37a4afdfd797a41ec7ce9461f83efe9 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 1.7E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c36810 c37a4afdfd797a41ec7ce9461f83efe9 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 1.7E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c36810 c37a4afdfd797a41ec7ce9461f83efe9 240 SUPERFAMILY SSF46785 2 74 7.32E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c36810 c37a4afdfd797a41ec7ce9461f83efe9 240 Gene3D G3DSA:1.20.120.530 96 236 1.3E-30 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c36810 c37a4afdfd797a41ec7ce9461f83efe9 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 70 3.4E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c27620 2eb1e4b0155d5e091ae4c3edab1d12b6 419 SUPERFAMILY SSF53474 19 417 2.25E-15 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c27620 2eb1e4b0155d5e091ae4c3edab1d12b6 419 Gene3D G3DSA:3.40.50.1820 25 289 3.3E-7 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c27620 2eb1e4b0155d5e091ae4c3edab1d12b6 419 Gene3D G3DSA:3.40.50.1820 290 418 1.7E-5 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c08840 81d13b39845a2bfa6a9c85cf6ece8d4f 398 Gene3D G3DSA:3.40.50.1820 28 368 9.0E-139 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c08840 81d13b39845a2bfa6a9c85cf6ece8d4f 398 Gene3D G3DSA:1.10.1740.110 189 298 9.0E-139 T 12-10-2018 MIM_c08840 81d13b39845a2bfa6a9c85cf6ece8d4f 398 SUPERFAMILY SSF53474 16 377 3.08E-104 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c08840 81d13b39845a2bfa6a9c85cf6ece8d4f 398 Pfam PF00561 alpha/beta hydrolase fold 53 367 2.1E-35 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c08840 81d13b39845a2bfa6a9c85cf6ece8d4f 398 Hamap MF_00296 Homoserine O-acetyltransferase [metXA]. 4 380 29.746 T 12-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 MIM_c08840 81d13b39845a2bfa6a9c85cf6ece8d4f 398 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 23 378 1.2E-137 T 12-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 MIM_c08840 81d13b39845a2bfa6a9c85cf6ece8d4f 398 PIRSF PIRSF000443 1 389 1.6E-143 T 12-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 MIM_c28700 76f3206c53630400b4ce6d88c4c7b8b7 154 Hamap MF_00042 Ribonuclease H [rnhA]. 3 151 33.25 T 12-10-2018 IPR022892 Ribonuclease HI GO:0004523 MIM_c28700 76f3206c53630400b4ce6d88c4c7b8b7 154 Gene3D G3DSA:3.30.420.10 1 152 1.9E-57 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MIM_c28700 76f3206c53630400b4ce6d88c4c7b8b7 154 Pfam PF00075 RNase H 5 142 1.5E-47 T 12-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 MIM_c28700 76f3206c53630400b4ce6d88c4c7b8b7 154 SUPERFAMILY SSF53098 4 143 1.77E-55 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily MIM_c12130 0d69fd8347cb408bff842f4d79e24d76 254 SUPERFAMILY SSF161098 33 230 2.09E-37 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c12130 0d69fd8347cb408bff842f4d79e24d76 254 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 54 244 1.2E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c12130 0d69fd8347cb408bff842f4d79e24d76 254 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 30 99 8.4E-18 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c12130 0d69fd8347cb408bff842f4d79e24d76 254 Gene3D G3DSA:1.10.3720.10 25 245 5.6E-48 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c17180 a14528ba0cf9160e6b715877056ca089 226 Gene3D G3DSA:3.60.21.10 1 222 2.6E-46 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like MIM_c17180 a14528ba0cf9160e6b715877056ca089 226 SUPERFAMILY SSF56300 9 220 2.43E-34 T 12-10-2018 MIM_c17180 a14528ba0cf9160e6b715877056ca089 226 Pfam PF00149 Calcineurin-like phosphoesterase 17 184 1.1E-8 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MIM_c33850 73b84c732b180cff148aeee3ca738176 300 Pfam PF03466 LysR substrate binding domain 89 291 1.3E-35 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c33850 73b84c732b180cff148aeee3ca738176 300 Gene3D G3DSA:1.10.10.10 1 83 2.5E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c33850 73b84c732b180cff148aeee3ca738176 300 Gene3D G3DSA:3.40.190.290 93 298 1.1E-36 T 12-10-2018 MIM_c33850 73b84c732b180cff148aeee3ca738176 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 3.7E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c33850 73b84c732b180cff148aeee3ca738176 300 SUPERFAMILY SSF53850 91 297 5.12E-36 T 12-10-2018 MIM_c33850 73b84c732b180cff148aeee3ca738176 300 SUPERFAMILY SSF46785 2 112 4.79E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c18810 751068566c8745ae3fa262fec15dde72 285 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 33 280 9.0E-72 T 12-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 MIM_c18810 751068566c8745ae3fa262fec15dde72 285 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 2 272 40.081 T 12-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 MIM_c18810 751068566c8745ae3fa262fec15dde72 285 Gene3D G3DSA:3.40.50.150 1 285 2.8E-108 T 12-10-2018 MIM_c18810 751068566c8745ae3fa262fec15dde72 285 SUPERFAMILY SSF53335 9 282 9.97E-89 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c19000 dea6e01547190402483f04eaceb81fde 128 SUPERFAMILY SSF55298 1 128 1.45E-42 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MIM_c19000 dea6e01547190402483f04eaceb81fde 128 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 127 1.8E-43 T 12-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 MIM_c19000 dea6e01547190402483f04eaceb81fde 128 Gene3D G3DSA:3.30.1330.40 1 128 2.0E-47 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MIM_c19000 dea6e01547190402483f04eaceb81fde 128 Pfam PF01042 Endoribonuclease L-PSP 9 127 2.4E-38 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 MIM_c00480 4e8be82c93aab7d968d0062d0c8ce31b 321 Gene3D G3DSA:3.40.190.150 26 311 5.4E-109 T 12-10-2018 MIM_c00480 4e8be82c93aab7d968d0062d0c8ce31b 321 SUPERFAMILY SSF53850 111 282 3.62E-14 T 12-10-2018 MIM_c00480 4e8be82c93aab7d968d0062d0c8ce31b 321 PIRSF PIRSF017082 1 321 1.5E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c00480 4e8be82c93aab7d968d0062d0c8ce31b 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 317 1.4E-82 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c00480 4e8be82c93aab7d968d0062d0c8ce31b 321 Gene3D G3DSA:3.40.190.10 123 246 5.4E-109 T 12-10-2018 MIM_c31800 e9273b9a54643977f5068e8906dded60 212 Gene3D G3DSA:2.30.110.10 1 206 1.1E-63 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MIM_c31800 e9273b9a54643977f5068e8906dded60 212 Pfam PF04299 Putative FMN-binding domain 1 168 3.6E-63 T 12-10-2018 IPR007396 Transcriptional regulator PAI 2-type MIM_c31800 e9273b9a54643977f5068e8906dded60 212 SUPERFAMILY SSF50475 12 186 3.83E-36 T 12-10-2018 MIM_c31800 e9273b9a54643977f5068e8906dded60 212 PIRSF PIRSF010372 1 212 5.0E-80 T 12-10-2018 IPR007396 Transcriptional regulator PAI 2-type MIM_c41100 ee60e3ae63fb422f3f871473be568fc3 447 SUPERFAMILY SSF103378 4 440 7.45E-104 T 12-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 MIM_c41100 ee60e3ae63fb422f3f871473be568fc3 447 Gene3D G3DSA:1.10.4100.10 23 414 2.5E-97 T 12-10-2018 MIM_c41100 ee60e3ae63fb422f3f871473be568fc3 447 Pfam PF03972 MmgE/PrpD family 18 436 9.8E-111 T 12-10-2018 IPR005656 MmgE/PrpD GO:0016829 MIM_c41100 ee60e3ae63fb422f3f871473be568fc3 447 Gene3D G3DSA:3.30.1330.120 267 398 2.5E-97 T 12-10-2018 MIM_c24150 0c84a85f0c257213d742ea3097de5d1e 107 Pfam PF00037 4Fe-4S binding domain 34 55 2.8E-6 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MIM_c24150 0c84a85f0c257213d742ea3097de5d1e 107 Gene3D G3DSA:3.30.70.20 2 98 9.6E-31 T 12-10-2018 MIM_c24150 0c84a85f0c257213d742ea3097de5d1e 107 PRINTS PR00354 7Fe ferredoxin signature 19 29 1.8E-15 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 MIM_c24150 0c84a85f0c257213d742ea3097de5d1e 107 PRINTS PR00354 7Fe ferredoxin signature 9 19 1.8E-15 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 MIM_c24150 0c84a85f0c257213d742ea3097de5d1e 107 PRINTS PR00354 7Fe ferredoxin signature 35 52 1.8E-15 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 MIM_c24150 0c84a85f0c257213d742ea3097de5d1e 107 SUPERFAMILY SSF54862 1 100 4.19E-23 T 12-10-2018 MIM_c24150 0c84a85f0c257213d742ea3097de5d1e 107 Pfam PF11953 Domain of unknown function (DUF3470) 67 107 2.2E-17 T 12-10-2018 IPR022569 Ferredoxin, C-terminal MIM_c24150 0c84a85f0c257213d742ea3097de5d1e 107 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MIM_c36880 005d2b06cbc636a7cf96a43a0f85201d 433 SUPERFAMILY SSF51905 3 340 2.54E-29 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c36880 005d2b06cbc636a7cf96a43a0f85201d 433 Gene3D G3DSA:3.50.50.100 2 415 6.6E-105 T 12-10-2018 MIM_c36880 005d2b06cbc636a7cf96a43a0f85201d 433 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 170 188 2.6E-19 T 12-10-2018 MIM_c36880 005d2b06cbc636a7cf96a43a0f85201d 433 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 2.6E-19 T 12-10-2018 MIM_c36880 005d2b06cbc636a7cf96a43a0f85201d 433 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 292 314 2.6E-19 T 12-10-2018 MIM_c36880 005d2b06cbc636a7cf96a43a0f85201d 433 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 129 2.6E-19 T 12-10-2018 MIM_c36880 005d2b06cbc636a7cf96a43a0f85201d 433 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 335 3.2E-59 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MIM_c36880 005d2b06cbc636a7cf96a43a0f85201d 433 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 307 314 4.1E-10 T 12-10-2018 MIM_c36880 005d2b06cbc636a7cf96a43a0f85201d 433 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 170 195 4.1E-10 T 12-10-2018 MIM_c36880 005d2b06cbc636a7cf96a43a0f85201d 433 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 4.1E-10 T 12-10-2018 MIM_c37940 6ce1a2a431700cd004b75be2a0928303 361 Gene3D G3DSA:3.40.50.300 1 218 2.3E-68 T 12-10-2018 MIM_c37940 6ce1a2a431700cd004b75be2a0928303 361 SMART SM00382 25 208 2.4E-20 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c37940 6ce1a2a431700cd004b75be2a0928303 361 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 31 353 3.1E-107 T 12-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 MIM_c37940 6ce1a2a431700cd004b75be2a0928303 361 Gene3D G3DSA:2.40.50.140 288 345 1.2E-7 T 12-10-2018 MIM_c37940 6ce1a2a431700cd004b75be2a0928303 361 Pfam PF00005 ABC transporter 16 158 6.7E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c37940 6ce1a2a431700cd004b75be2a0928303 361 Pfam PF08402 TOBE domain 281 353 1.1E-11 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 MIM_c37940 6ce1a2a431700cd004b75be2a0928303 361 Gene3D G3DSA:2.40.50.940 219 350 1.2E-7 T 12-10-2018 MIM_c37940 6ce1a2a431700cd004b75be2a0928303 361 SUPERFAMILY SSF50331 234 353 6.23E-14 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MIM_c37940 6ce1a2a431700cd004b75be2a0928303 361 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c37940 6ce1a2a431700cd004b75be2a0928303 361 SUPERFAMILY SSF52540 1 241 3.64E-84 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c13250 72d182c3a5061422767841d5f1328982 592 Gene3D G3DSA:1.20.58.100 435 551 2.9E-33 T 12-10-2018 MIM_c13250 72d182c3a5061422767841d5f1328982 592 Gene3D G3DSA:4.10.80.40 552 592 4.8E-10 T 12-10-2018 MIM_c13250 72d182c3a5061422767841d5f1328982 592 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 14 591 6.9E-239 T 12-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MIM_c13250 72d182c3a5061422767841d5f1328982 592 Gene3D G3DSA:3.90.700.10 251 354 4.8E-163 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 MIM_c13250 72d182c3a5061422767841d5f1328982 592 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 48 57 - T 12-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MIM_c13250 72d182c3a5061422767841d5f1328982 592 Pfam PF02910 Fumarate reductase flavoprotein C-term 467 591 2.3E-39 T 12-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MIM_c13250 72d182c3a5061422767841d5f1328982 592 Gene3D G3DSA:3.50.50.60 14 419 4.8E-163 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c13250 72d182c3a5061422767841d5f1328982 592 SUPERFAMILY SSF51905 10 431 4.92E-79 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c13250 72d182c3a5061422767841d5f1328982 592 SUPERFAMILY SSF46977 456 592 1.23E-45 T 12-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MIM_c13250 72d182c3a5061422767841d5f1328982 592 SUPERFAMILY SSF56425 241 359 8.97E-43 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 MIM_c13250 72d182c3a5061422767841d5f1328982 592 Pfam PF00890 FAD binding domain 14 408 7.6E-117 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MIM_c13250 72d182c3a5061422767841d5f1328982 592 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 14 36 4.5E-6 T 12-10-2018 MIM_c13250 72d182c3a5061422767841d5f1328982 592 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 386 393 4.5E-6 T 12-10-2018 MIM_c13250 72d182c3a5061422767841d5f1328982 592 PIRSF PIRSF000171 4 583 1.5E-41 T 12-10-2018 MIM_c13250 72d182c3a5061422767841d5f1328982 592 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 11 592 5.6E-279 T 12-10-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MIM_c18630 7690930b197e2ed5de39112bd68f6260 416 Gene3D G3DSA:3.30.70.360 209 329 8.8E-127 T 12-10-2018 MIM_c18630 7690930b197e2ed5de39112bd68f6260 416 PIRSF PIRSF001235 1 415 1.3E-129 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 MIM_c18630 7690930b197e2ed5de39112bd68f6260 416 Gene3D G3DSA:3.40.630.10 25 405 8.8E-127 T 12-10-2018 MIM_c18630 7690930b197e2ed5de39112bd68f6260 416 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 75 84 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 MIM_c18630 7690930b197e2ed5de39112bd68f6260 416 Pfam PF01546 Peptidase family M20/M25/M40 76 408 1.2E-32 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 MIM_c18630 7690930b197e2ed5de39112bd68f6260 416 SUPERFAMILY SSF53187 2 411 4.0E-77 T 12-10-2018 MIM_c18630 7690930b197e2ed5de39112bd68f6260 416 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 7 407 6.2E-108 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 MIM_c18630 7690930b197e2ed5de39112bd68f6260 416 Pfam PF07687 Peptidase dimerisation domain 209 315 5.1E-9 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain MIM_c18630 7690930b197e2ed5de39112bd68f6260 416 SUPERFAMILY SSF55031 209 319 1.11E-24 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain MIM_c28090 0a506cbe91286c2f4534cc276f77c751 170 Gene3D G3DSA:3.60.15.10 9 126 5.6E-16 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MIM_c28090 0a506cbe91286c2f4534cc276f77c751 170 Pfam PF00753 Metallo-beta-lactamase superfamily 32 108 1.9E-7 T 12-10-2018 IPR001279 Metallo-beta-lactamase MIM_c28090 0a506cbe91286c2f4534cc276f77c751 170 SUPERFAMILY SSF56281 32 126 3.78E-17 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MIM_c18990 9d9e410790df49509a42bb9f8c054348 343 Pfam PF13343 Bacterial extracellular solute-binding protein 76 307 4.9E-19 T 12-10-2018 MIM_c18990 9d9e410790df49509a42bb9f8c054348 343 PIRSF PIRSF002825 1 343 7.9E-82 T 12-10-2018 IPR026045 Ferric binding protein MIM_c18990 9d9e410790df49509a42bb9f8c054348 343 SUPERFAMILY SSF53850 25 341 1.04E-77 T 12-10-2018 MIM_c18990 9d9e410790df49509a42bb9f8c054348 343 Gene3D G3DSA:3.40.190.10 30 303 2.1E-123 T 12-10-2018 MIM_c18990 9d9e410790df49509a42bb9f8c054348 343 Gene3D G3DSA:3.40.190.10 123 336 2.1E-123 T 12-10-2018 MIM_c04700 a2c79f8bd063fcc5f0c3603ebd9a84ed 632 SUPERFAMILY SSF53649 271 587 6.54E-60 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 MIM_c04700 a2c79f8bd063fcc5f0c3603ebd9a84ed 632 PIRSF PIRSF005091 4 605 1.9E-78 T 12-10-2018 IPR012160 Lipoteichoic acid synthase-like MIM_c04700 a2c79f8bd063fcc5f0c3603ebd9a84ed 632 Gene3D G3DSA:3.40.720.10 268 549 5.4E-116 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 MIM_c04700 a2c79f8bd063fcc5f0c3603ebd9a84ed 632 Pfam PF00884 Sulfatase 273 542 1.5E-36 T 12-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 MIM_c04700 a2c79f8bd063fcc5f0c3603ebd9a84ed 632 Gene3D G3DSA:3.30.1120.80 551 626 5.4E-116 T 12-10-2018 MIM_c01860 7364dc9544db0b571f2255e715035620 331 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 39 296 5.8E-24 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 MIM_c01860 7364dc9544db0b571f2255e715035620 331 Gene3D G3DSA:3.40.190.170 28 324 8.4E-60 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily MIM_c01230 905a1a5a2c2bc0ca04f2a5a13ac3d65e 134 Gene3D G3DSA:3.30.1330.40 1 129 3.5E-40 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MIM_c01230 905a1a5a2c2bc0ca04f2a5a13ac3d65e 134 Pfam PF01042 Endoribonuclease L-PSP 13 127 2.1E-26 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 MIM_c01230 905a1a5a2c2bc0ca04f2a5a13ac3d65e 134 SUPERFAMILY SSF55298 10 128 1.04E-35 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MIM_c24630 45d610839bf198d4703476abcda53ef8 152 SUPERFAMILY SSF49503 26 150 1.1E-40 T 12-10-2018 IPR008972 Cupredoxin MIM_c24630 45d610839bf198d4703476abcda53ef8 152 Gene3D G3DSA:2.60.40.420 26 150 3.3E-41 T 12-10-2018 IPR008972 Cupredoxin MIM_c24630 45d610839bf198d4703476abcda53ef8 152 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 26 150 1.1E-27 T 12-10-2018 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 MIM_c24630 45d610839bf198d4703476abcda53ef8 152 ProDom PD003655 COPPER ELECTRON AZURIN METAL-BINDING PERIPLASMIC PRECURSOR SIGNAL SEQUENCING DIRECT MEMBRANE 32 148 8.0E-43 T 12-10-2018 MIM_c24630 45d610839bf198d4703476abcda53ef8 152 TIGRFAM TIGR02695 azurin: azurin 28 150 2.0E-58 T 12-10-2018 IPR014068 Azurin MIM_c17280 4e9a5daa4ef430cfa27a5f3eab061ede 287 Gene3D G3DSA:3.20.20.140 10 287 1.4E-83 T 12-10-2018 MIM_c17280 4e9a5daa4ef430cfa27a5f3eab061ede 287 Pfam PF04909 Amidohydrolase 23 285 7.3E-43 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MIM_c17280 4e9a5daa4ef430cfa27a5f3eab061ede 287 SUPERFAMILY SSF51556 18 285 2.65E-78 T 12-10-2018 IPR032466 Metal-dependent hydrolase MIM_c36630 f0734e10700d53206980a1f99d7f9d31 275 Gene3D G3DSA:1.10.3720.10 71 268 9.8E-28 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c36630 f0734e10700d53206980a1f99d7f9d31 275 SUPERFAMILY SSF161098 76 261 4.84E-35 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c36630 f0734e10700d53206980a1f99d7f9d31 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 268 2.6E-27 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c14400 6ef713fc027b45bc3dc3120d83f9cfc4 208 SUPERFAMILY SSF53633 1 143 2.23E-6 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MIM_c14400 6ef713fc027b45bc3dc3120d83f9cfc4 208 Gene3D G3DSA:3.40.1160.10 1 180 1.2E-11 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MIM_c13810 caae9d3fce039098073a457b5442fad2 260 Gene3D G3DSA:1.10.12.10 201 257 1.1E-18 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MIM_c13810 caae9d3fce039098073a457b5442fad2 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 257 2.9E-54 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c13810 caae9d3fce039098073a457b5442fad2 260 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 MIM_c13810 caae9d3fce039098073a457b5442fad2 260 Gene3D G3DSA:3.90.226.10 1 199 7.8E-61 T 12-10-2018 MIM_c13810 caae9d3fce039098073a457b5442fad2 260 SUPERFAMILY SSF52096 2 257 6.64E-77 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_24p00080 176ce200335ca2313c52e70f5e388100 344 Pfam PF07883 Cupin domain 96 164 2.1E-21 T 12-10-2018 IPR013096 Cupin 2, conserved barrel MIM_24p00080 176ce200335ca2313c52e70f5e388100 344 SUPERFAMILY SSF51182 8 341 7.76E-89 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_24p00080 176ce200335ca2313c52e70f5e388100 344 Gene3D G3DSA:2.60.120.10 10 344 2.3E-91 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c11820 e32e8139f5512028579a106ba99d2f75 446 Pfam PF12002 MgsA AAA+ ATPase C terminal 266 432 4.4E-67 T 12-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal MIM_c11820 e32e8139f5512028579a106ba99d2f75 446 Gene3D G3DSA:1.10.3710.10 344 445 1.2E-34 T 12-10-2018 MIM_c11820 e32e8139f5512028579a106ba99d2f75 446 Gene3D G3DSA:3.40.50.300 13 168 1.3E-42 T 12-10-2018 MIM_c11820 e32e8139f5512028579a106ba99d2f75 446 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 58 164 9.6E-13 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MIM_c11820 e32e8139f5512028579a106ba99d2f75 446 SUPERFAMILY SSF48019 250 432 1.64E-72 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MIM_c11820 e32e8139f5512028579a106ba99d2f75 446 Gene3D G3DSA:1.10.8.60 170 237 1.3E-5 T 12-10-2018 MIM_c11820 e32e8139f5512028579a106ba99d2f75 446 SMART SM00382 54 170 8.3E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c11820 e32e8139f5512028579a106ba99d2f75 446 SUPERFAMILY SSF52540 17 234 6.09E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c11820 e32e8139f5512028579a106ba99d2f75 446 Gene3D G3DSA:1.20.272.10 241 343 8.4E-42 T 12-10-2018 MIM_c11820 e32e8139f5512028579a106ba99d2f75 446 Pfam PF16193 AAA C-terminal domain 189 265 6.0E-21 T 12-10-2018 IPR032423 AAA C-terminal domain MIM_c35620 790dd6d2f5a8b3257a382b61c375a2bd 333 Pfam PF00296 Luciferase-like monooxygenase 1 244 2.7E-31 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MIM_c35620 790dd6d2f5a8b3257a382b61c375a2bd 333 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 3 330 2.8E-68 T 12-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 MIM_c35620 790dd6d2f5a8b3257a382b61c375a2bd 333 SUPERFAMILY SSF51679 1 329 1.41E-50 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MIM_c35620 790dd6d2f5a8b3257a382b61c375a2bd 333 Gene3D G3DSA:3.20.20.30 1 333 6.6E-72 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MIM_c04280 b113ef87bf0b740a15886c1daf5747e0 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 314 2.4E-47 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c04280 b113ef87bf0b740a15886c1daf5747e0 320 PIRSF PIRSF017082 2 318 4.5E-56 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c04280 b113ef87bf0b740a15886c1daf5747e0 320 Gene3D G3DSA:3.40.190.150 29 309 3.4E-80 T 12-10-2018 MIM_c04280 b113ef87bf0b740a15886c1daf5747e0 320 Gene3D G3DSA:3.40.190.10 126 245 3.4E-80 T 12-10-2018 MIM_c26110 286c345a34dbdd5d4368f8be3bc05924 319 ProSitePatterns PS01054 Transaldolase signature 1. 30 38 - T 12-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 MIM_c26110 286c345a34dbdd5d4368f8be3bc05924 319 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 13 310 3.2E-94 T 12-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 MIM_c26110 286c345a34dbdd5d4368f8be3bc05924 319 SUPERFAMILY SSF51569 1 315 5.86E-110 T 12-10-2018 MIM_c26110 286c345a34dbdd5d4368f8be3bc05924 319 TIGRFAM TIGR00874 talAB: transaldolase 2 314 3.3E-131 T 12-10-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 MIM_c26110 286c345a34dbdd5d4368f8be3bc05924 319 Gene3D G3DSA:3.20.20.70 1 318 1.9E-130 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c26110 286c345a34dbdd5d4368f8be3bc05924 319 ProSitePatterns PS00958 Transaldolase active site. 122 139 - T 12-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 MIM_c26110 286c345a34dbdd5d4368f8be3bc05924 319 Hamap MF_00492 Transaldolase [tal]. 1 316 47.787 T 12-10-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 MIM_c27070 8d5cc6ed052f0c85307dad5a4000c33c 152 SUPERFAMILY SSF54637 2 141 1.81E-33 T 12-10-2018 IPR029069 HotDog domain superfamily MIM_c27070 8d5cc6ed052f0c85307dad5a4000c33c 152 Gene3D G3DSA:3.10.129.10 1 146 1.7E-39 T 12-10-2018 MIM_c27070 8d5cc6ed052f0c85307dad5a4000c33c 152 Pfam PF01575 MaoC like domain 8 110 5.2E-18 T 12-10-2018 IPR002539 MaoC-like dehydratase domain MIM_c36780 e7d51a67ad2f34d9e517e4f9d561a7e2 319 SUPERFAMILY SSF53850 109 279 1.85E-9 T 12-10-2018 MIM_c36780 e7d51a67ad2f34d9e517e4f9d561a7e2 319 PIRSF PIRSF017082 1 319 1.1E-102 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c36780 e7d51a67ad2f34d9e517e4f9d561a7e2 319 Gene3D G3DSA:3.40.190.10 122 245 1.3E-91 T 12-10-2018 MIM_c36780 e7d51a67ad2f34d9e517e4f9d561a7e2 319 Gene3D G3DSA:3.40.190.150 27 309 1.3E-91 T 12-10-2018 MIM_c36780 e7d51a67ad2f34d9e517e4f9d561a7e2 319 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 314 6.3E-66 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c12090 60e25235d84cfd5016597401fc15cbae 212 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 5 210 4.8E-83 T 12-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 MIM_c12090 60e25235d84cfd5016597401fc15cbae 212 SMART SM00882 7 204 1.0E-55 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MIM_c12090 60e25235d84cfd5016597401fc15cbae 212 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 45 53 - T 12-10-2018 IPR004164 Coenzyme A transferase active site GO:0008410 Reactome: R-HSA-77108 MIM_c12090 60e25235d84cfd5016597401fc15cbae 212 SUPERFAMILY SSF100950 6 211 9.21E-58 T 12-10-2018 IPR037171 NagB/RpiA transferase-like MIM_c12090 60e25235d84cfd5016597401fc15cbae 212 Gene3D G3DSA:3.40.1080.10 2 212 6.5E-80 T 12-10-2018 MIM_c12090 60e25235d84cfd5016597401fc15cbae 212 Pfam PF01144 Coenzyme A transferase 7 186 2.1E-35 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MIM_c29830 f517539a89274f0f3e009bc2690dd93d 158 SUPERFAMILY SSF46785 5 65 1.56E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c29830 f517539a89274f0f3e009bc2690dd93d 158 Pfam PF01037 Lrp/AsnC ligand binding domain 72 147 1.6E-21 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MIM_c29830 f517539a89274f0f3e009bc2690dd93d 158 SUPERFAMILY SSF54909 68 156 1.88E-18 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel MIM_c29830 f517539a89274f0f3e009bc2690dd93d 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 4.7E-17 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MIM_c29830 f517539a89274f0f3e009bc2690dd93d 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 4.7E-17 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MIM_c29830 f517539a89274f0f3e009bc2690dd93d 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 4.7E-17 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MIM_c29830 f517539a89274f0f3e009bc2690dd93d 158 Gene3D G3DSA:1.10.10.10 7 57 1.7E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c29830 f517539a89274f0f3e009bc2690dd93d 158 Gene3D G3DSA:3.30.70.920 59 146 2.0E-26 T 12-10-2018 MIM_c29830 f517539a89274f0f3e009bc2690dd93d 158 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 53 4.3E-22 T 12-10-2018 MIM_c29830 f517539a89274f0f3e009bc2690dd93d 158 SMART SM00344 6 118 1.7E-41 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MIM_c29830 f517539a89274f0f3e009bc2690dd93d 158 ProSitePatterns PS00519 AsnC-type HTH domain signature. 24 50 - T 12-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site MIM_c20220 6f08744f6f8f7537140e3d96d6f6bc69 453 Pfam PF03972 MmgE/PrpD family 6 436 4.9E-92 T 12-10-2018 IPR005656 MmgE/PrpD GO:0016829 MIM_c20220 6f08744f6f8f7537140e3d96d6f6bc69 453 Gene3D G3DSA:1.10.4100.10 24 419 2.9E-89 T 12-10-2018 MIM_c20220 6f08744f6f8f7537140e3d96d6f6bc69 453 Gene3D G3DSA:3.30.1330.120 268 401 2.9E-89 T 12-10-2018 MIM_c20220 6f08744f6f8f7537140e3d96d6f6bc69 453 SUPERFAMILY SSF103378 2 441 1.83E-83 T 12-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 MIM_c32200 e36986fc15514e148481d535fa5018eb 157 Gene3D G3DSA:1.10.10.10 5 153 2.8E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c32200 e36986fc15514e148481d535fa5018eb 157 SMART SM00347 36 138 8.3E-16 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c32200 e36986fc15514e148481d535fa5018eb 157 Pfam PF01047 MarR family 45 102 2.7E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c32200 e36986fc15514e148481d535fa5018eb 157 SUPERFAMILY SSF46785 11 150 4.96E-30 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c32200 e36986fc15514e148481d535fa5018eb 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 128 148 2.8E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c32200 e36986fc15514e148481d535fa5018eb 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 98 114 2.8E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c32200 e36986fc15514e148481d535fa5018eb 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 79 94 2.8E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c32200 e36986fc15514e148481d535fa5018eb 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 78 2.8E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c36430 e9d1911aa089b2cb450a163235c95646 453 Pfam PF01235 Sodium:alanine symporter family 64 451 4.0E-155 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MIM_c36430 e9d1911aa089b2cb450a163235c95646 453 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 99 114 - T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MIM_c36430 e9d1911aa089b2cb450a163235c95646 453 TIGRFAM TIGR00835 agcS: amino acid carrier protein 19 443 2.0E-159 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MIM_c36430 e9d1911aa089b2cb450a163235c95646 453 PRINTS PR00175 Sodium/alanine symporter signature 99 121 1.2E-57 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MIM_c36430 e9d1911aa089b2cb450a163235c95646 453 PRINTS PR00175 Sodium/alanine symporter signature 190 208 1.2E-57 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MIM_c36430 e9d1911aa089b2cb450a163235c95646 453 PRINTS PR00175 Sodium/alanine symporter signature 218 237 1.2E-57 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MIM_c36430 e9d1911aa089b2cb450a163235c95646 453 PRINTS PR00175 Sodium/alanine symporter signature 353 375 1.2E-57 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MIM_c36430 e9d1911aa089b2cb450a163235c95646 453 PRINTS PR00175 Sodium/alanine symporter signature 412 432 1.2E-57 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MIM_c36430 e9d1911aa089b2cb450a163235c95646 453 PRINTS PR00175 Sodium/alanine symporter signature 309 327 1.2E-57 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MIM_c35490 5a375a439a9b5ba9b78969f4d3d9d2b4 312 SUPERFAMILY SSF161098 90 295 1.96E-25 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c35490 5a375a439a9b5ba9b78969f4d3d9d2b4 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 310 2.8E-39 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c35490 5a375a439a9b5ba9b78969f4d3d9d2b4 312 Gene3D G3DSA:1.10.3720.10 87 303 5.0E-29 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c16860 1f98bc0e5074b7aa0aec8e9d96eb5212 380 Gene3D G3DSA:3.40.630.10 12 367 1.3E-129 T 12-10-2018 MIM_c16860 1f98bc0e5074b7aa0aec8e9d96eb5212 380 SUPERFAMILY SSF53187 8 378 9.69E-65 T 12-10-2018 MIM_c16860 1f98bc0e5074b7aa0aec8e9d96eb5212 380 Pfam PF01546 Peptidase family M20/M25/M40 67 377 7.9E-47 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 MIM_c16860 1f98bc0e5074b7aa0aec8e9d96eb5212 380 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 102 140 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 MIM_c16860 1f98bc0e5074b7aa0aec8e9d96eb5212 380 Pfam PF07687 Peptidase dimerisation domain 180 285 2.6E-25 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain MIM_c16860 1f98bc0e5074b7aa0aec8e9d96eb5212 380 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 10 378 7.5E-161 T 12-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 MIM_c16860 1f98bc0e5074b7aa0aec8e9d96eb5212 380 Gene3D G3DSA:3.30.70.360 184 297 1.3E-129 T 12-10-2018 MIM_c16860 1f98bc0e5074b7aa0aec8e9d96eb5212 380 SUPERFAMILY SSF55031 184 293 2.69E-30 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain MIM_c16860 1f98bc0e5074b7aa0aec8e9d96eb5212 380 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 7 380 51.111 T 12-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 MIM_c23930 6d0c11b9d8eb1a56740035f7604e98d5 324 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 235 324 6.5E-34 T 12-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MIM_c23930 6d0c11b9d8eb1a56740035f7604e98d5 324 SUPERFAMILY SSF53901 3 323 2.13E-69 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c23930 6d0c11b9d8eb1a56740035f7604e98d5 324 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 3 323 3.4E-121 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MIM_c23930 6d0c11b9d8eb1a56740035f7604e98d5 324 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 112 189 1.5E-34 T 12-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MIM_c23930 6d0c11b9d8eb1a56740035f7604e98d5 324 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 324 67.887 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MIM_c23930 6d0c11b9d8eb1a56740035f7604e98d5 324 Gene3D G3DSA:3.40.47.10 1 324 1.8E-124 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c13690 c72cdd2c48ab17165315d4ed707c9ae0 260 SUPERFAMILY SSF69118 47 256 1.76E-35 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c13690 c72cdd2c48ab17165315d4ed707c9ae0 260 Pfam PF02627 Carboxymuconolactone decarboxylase family 170 252 2.4E-9 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c13690 c72cdd2c48ab17165315d4ed707c9ae0 260 Gene3D G3DSA:1.20.1290.10 28 258 6.9E-47 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c19430 4db123910336e2ecee72276ec1b58bce 361 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 38 108 1.4E-21 T 12-10-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 MIM_c19430 4db123910336e2ecee72276ec1b58bce 361 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 225 241 0.13 T 12-10-2018 IPR001451 Hexapeptide repeat MIM_c19430 4db123910336e2ecee72276ec1b58bce 361 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 37 354 4.4E-110 T 12-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 MIM_c19430 4db123910336e2ecee72276ec1b58bce 361 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 283 311 0.0017 T 12-10-2018 IPR001451 Hexapeptide repeat MIM_c19430 4db123910336e2ecee72276ec1b58bce 361 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 130 165 3.3E-9 T 12-10-2018 IPR001451 Hexapeptide repeat MIM_c19430 4db123910336e2ecee72276ec1b58bce 361 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 247 282 9.4E-6 T 12-10-2018 IPR001451 Hexapeptide repeat MIM_c19430 4db123910336e2ecee72276ec1b58bce 361 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 167 200 6.5E-6 T 12-10-2018 IPR001451 Hexapeptide repeat MIM_c19430 4db123910336e2ecee72276ec1b58bce 361 SUPERFAMILY SSF51161 49 341 3.65E-79 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily MIM_c19430 4db123910336e2ecee72276ec1b58bce 361 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 9 351 35.978 T 12-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 MIM_c19430 4db123910336e2ecee72276ec1b58bce 361 Gene3D G3DSA:3.40.1390.10 20 116 2.2E-19 T 12-10-2018 MIM_c19430 4db123910336e2ecee72276ec1b58bce 361 Gene3D G3DSA:2.160.10.10 121 333 2.4E-63 T 12-10-2018 MIM_c11840 9370969c496e7963a60e843a1fdce75b 256 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 255 35.168 T 12-10-2018 IPR005583 Peroxide stress protein YaaA MIM_c11840 9370969c496e7963a60e843a1fdce75b 256 Pfam PF03883 Peroxide stress protein YaaA 1 243 1.1E-90 T 12-10-2018 IPR005583 Peroxide stress protein YaaA MIM_c34410 f968ef29aae782fff6e84817f703bd0c 517 ProSitePatterns PS00455 Putative AMP-binding domain signature. 160 171 - T 12-10-2018 IPR020845 AMP-binding, conserved site MIM_c34410 f968ef29aae782fff6e84817f703bd0c 517 Pfam PF13193 AMP-binding enzyme C-terminal domain 419 492 1.3E-18 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MIM_c34410 f968ef29aae782fff6e84817f703bd0c 517 Gene3D G3DSA:3.40.50.12780 1 403 9.2E-96 T 12-10-2018 MIM_c34410 f968ef29aae782fff6e84817f703bd0c 517 SUPERFAMILY SSF56801 6 502 2.49E-130 T 12-10-2018 MIM_c34410 f968ef29aae782fff6e84817f703bd0c 517 Pfam PF00501 AMP-binding enzyme 10 409 1.1E-83 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MIM_c34410 f968ef29aae782fff6e84817f703bd0c 517 Gene3D G3DSA:3.30.300.310 405 504 6.0E-32 T 12-10-2018 MIM_c16590 93fbee5a5ec9df7f51459716858144b8 377 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 115 131 - T 12-10-2018 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MIM_c16590 93fbee5a5ec9df7f51459716858144b8 377 Pfam PF00268 Ribonucleotide reductase, small chain 32 333 4.2E-46 T 12-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MIM_c16590 93fbee5a5ec9df7f51459716858144b8 377 Gene3D G3DSA:1.10.620.20 2 341 2.3E-141 T 12-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 MIM_c16590 93fbee5a5ec9df7f51459716858144b8 377 SUPERFAMILY SSF47240 3 341 4.06E-110 T 12-10-2018 IPR009078 Ferritin-like superfamily MIM_c08050 dc309bf22743a9f64820c7484c08ccad 354 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 248 313 1.4E-18 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c08050 dc309bf22743a9f64820c7484c08ccad 354 Gene3D G3DSA:3.40.50.300 18 348 7.1E-101 T 12-10-2018 MIM_c08050 dc309bf22743a9f64820c7484c08ccad 354 Pfam PF00005 ABC transporter 47 196 9.7E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c08050 dc309bf22743a9f64820c7484c08ccad 354 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c08050 dc309bf22743a9f64820c7484c08ccad 354 SMART SM00382 55 254 1.3E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c08050 dc309bf22743a9f64820c7484c08ccad 354 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 246 332 1.4E-26 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c08050 dc309bf22743a9f64820c7484c08ccad 354 SUPERFAMILY SSF52540 20 268 1.52E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c07150 5f3cdd9737a65074ffbd4b6ad70ad684 391 Gene3D G3DSA:1.20.1250.20 10 384 8.0E-40 T 12-10-2018 MIM_c07150 5f3cdd9737a65074ffbd4b6ad70ad684 391 SUPERFAMILY SSF103473 12 385 6.8E-42 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c07150 5f3cdd9737a65074ffbd4b6ad70ad684 391 Pfam PF07690 Major Facilitator Superfamily 17 353 2.4E-25 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c24330 7580a555ed26d22da0f6717dd056b08e 463 SUPERFAMILY SSF53067 116 162 8.93E-6 T 12-10-2018 MIM_c24330 7580a555ed26d22da0f6717dd056b08e 463 Gene3D G3DSA:3.30.420.40 4 129 5.3E-28 T 12-10-2018 MIM_c24330 7580a555ed26d22da0f6717dd056b08e 463 SUPERFAMILY SSF53067 5 109 2.85E-21 T 12-10-2018 MIM_c24330 7580a555ed26d22da0f6717dd056b08e 463 Pfam PF00814 Glycoprotease family 37 138 3.3E-23 T 12-10-2018 IPR000905 Gcp-like domain MIM_c24330 7580a555ed26d22da0f6717dd056b08e 463 Pfam PF00583 Acetyltransferase (GNAT) family 328 434 3.8E-11 T 12-10-2018 IPR000182 GNAT domain MIM_c24330 7580a555ed26d22da0f6717dd056b08e 463 Gene3D G3DSA:3.40.630.30 315 462 1.4E-39 T 12-10-2018 MIM_c24330 7580a555ed26d22da0f6717dd056b08e 463 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 325 456 3.6E-28 T 12-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 MIM_c24330 7580a555ed26d22da0f6717dd056b08e 463 SUPERFAMILY SSF55729 316 459 1.44E-30 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c24330 7580a555ed26d22da0f6717dd056b08e 463 SUPERFAMILY SSF53067 200 260 4.66E-6 T 12-10-2018 MIM_c24330 7580a555ed26d22da0f6717dd056b08e 463 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 7 262 5.8E-46 T 12-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 MIM_c14850 c6a14a2494eead02bd171665fe1798f1 91 ProSitePatterns PS00057 Ribosomal protein S18 signature. 37 60 - T 12-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c14850 c6a14a2494eead02bd171665fe1798f1 91 TIGRFAM TIGR00165 S18: ribosomal protein bS18 21 88 4.1E-34 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c14850 c6a14a2494eead02bd171665fe1798f1 91 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 37 89 3.0E-20 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c14850 c6a14a2494eead02bd171665fe1798f1 91 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 18 89 20.77 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c14850 c6a14a2494eead02bd171665fe1798f1 91 Gene3D G3DSA:4.10.640.10 4 91 9.3E-27 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c14850 c6a14a2494eead02bd171665fe1798f1 91 SUPERFAMILY SSF46911 16 90 1.4E-28 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c14850 c6a14a2494eead02bd171665fe1798f1 91 Pfam PF01084 Ribosomal protein S18 35 84 2.6E-24 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c14850 c6a14a2494eead02bd171665fe1798f1 91 PRINTS PR00974 Ribosomal protein S18 family signature 62 76 6.7E-16 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c14850 c6a14a2494eead02bd171665fe1798f1 91 PRINTS PR00974 Ribosomal protein S18 family signature 44 54 6.7E-16 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c14850 c6a14a2494eead02bd171665fe1798f1 91 PRINTS PR00974 Ribosomal protein S18 family signature 76 86 6.7E-16 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c14850 c6a14a2494eead02bd171665fe1798f1 91 PRINTS PR00974 Ribosomal protein S18 family signature 54 61 6.7E-16 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c09670 041330d689bf33f411baf07e6a90ffd7 606 ProSitePatterns PS00211 ABC transporters family signature. 408 422 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c09670 041330d689bf33f411baf07e6a90ffd7 606 Pfam PF16326 ABC transporter C-terminal domain 533 601 5.3E-16 T 12-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 MIM_c09670 041330d689bf33f411baf07e6a90ffd7 606 SMART SM00382 311 481 1.3E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c09670 041330d689bf33f411baf07e6a90ffd7 606 SMART SM00382 31 197 7.6E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c09670 041330d689bf33f411baf07e6a90ffd7 606 Gene3D G3DSA:3.40.50.300 1 230 1.4E-57 T 12-10-2018 MIM_c09670 041330d689bf33f411baf07e6a90ffd7 606 Gene3D G3DSA:3.40.50.300 248 518 3.1E-67 T 12-10-2018 MIM_c09670 041330d689bf33f411baf07e6a90ffd7 606 SUPERFAMILY SSF52540 276 484 4.06E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c09670 041330d689bf33f411baf07e6a90ffd7 606 Pfam PF12848 ABC transporter 191 265 4.5E-11 T 12-10-2018 IPR032781 ABC-transporter extension domain MIM_c09670 041330d689bf33f411baf07e6a90ffd7 606 SUPERFAMILY SSF52540 4 204 2.19E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c09670 041330d689bf33f411baf07e6a90ffd7 606 Gene3D G3DSA:1.10.287.380 523 606 5.1E-17 T 12-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 MIM_c09670 041330d689bf33f411baf07e6a90ffd7 606 Pfam PF00005 ABC transporter 22 152 1.5E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c09670 041330d689bf33f411baf07e6a90ffd7 606 Pfam PF00005 ABC transporter 303 436 7.6E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c19050 633bef2a68f225f04d7999e02418b451 281 SUPERFAMILY SSF161098 4 277 5.36E-58 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c19050 633bef2a68f225f04d7999e02418b451 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 276 1.9E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c19050 633bef2a68f225f04d7999e02418b451 281 Gene3D G3DSA:1.10.3720.10 2 274 1.7E-52 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c21540 ea06796ec56238d91746be3d13f9eaf6 175 SUPERFAMILY SSF88946 10 79 8.24E-13 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MIM_c21540 ea06796ec56238d91746be3d13f9eaf6 175 Gene3D G3DSA:1.10.10.10 111 173 3.7E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c21540 ea06796ec56238d91746be3d13f9eaf6 175 SUPERFAMILY SSF88659 106 166 1.79E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MIM_c21540 ea06796ec56238d91746be3d13f9eaf6 175 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 165 3.3E-21 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MIM_c21540 ea06796ec56238d91746be3d13f9eaf6 175 Pfam PF04542 Sigma-70 region 2 15 83 5.3E-11 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MIM_c21540 ea06796ec56238d91746be3d13f9eaf6 175 Pfam PF08281 Sigma-70, region 4 113 166 1.9E-16 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MIM_c21540 ea06796ec56238d91746be3d13f9eaf6 175 Gene3D G3DSA:1.10.1740.10 1 80 1.0E-7 T 12-10-2018 MIM_c32450 c6f219ee3781204810ddbbabbbcd9dff 298 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 5 286 31.56 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 MIM_c32450 c6f219ee3781204810ddbbabbbcd9dff 298 Pfam PF00288 GHMP kinases N terminal domain 92 149 1.1E-10 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 MIM_c32450 c6f219ee3781204810ddbbabbbcd9dff 298 SUPERFAMILY SSF55060 165 270 5.76E-20 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily MIM_c32450 c6f219ee3781204810ddbbabbbcd9dff 298 PIRSF PIRSF010376 4 290 2.2E-82 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 MIM_c32450 c6f219ee3781204810ddbbabbbcd9dff 298 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 7 265 7.2E-76 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 MIM_c32450 c6f219ee3781204810ddbbabbbcd9dff 298 Gene3D G3DSA:3.30.230.10 2 163 6.9E-54 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MIM_c32450 c6f219ee3781204810ddbbabbbcd9dff 298 Gene3D G3DSA:3.30.70.890 165 298 9.0E-25 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily MIM_c32450 c6f219ee3781204810ddbbabbbcd9dff 298 SUPERFAMILY SSF54211 7 160 4.71E-44 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MIM_c32450 c6f219ee3781204810ddbbabbbcd9dff 298 Pfam PF08544 GHMP kinases C terminal 228 267 2.0E-4 T 12-10-2018 IPR013750 GHMP kinase, C-terminal domain MIM_c37260 b5d04dddd1ac6143201adfa30c25692b 239 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c37260 b5d04dddd1ac6143201adfa30c25692b 239 Pfam PF00005 ABC transporter 33 177 7.8E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c37260 b5d04dddd1ac6143201adfa30c25692b 239 Gene3D G3DSA:3.40.50.300 5 238 3.3E-47 T 12-10-2018 MIM_c37260 b5d04dddd1ac6143201adfa30c25692b 239 SUPERFAMILY SSF52540 12 232 1.36E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c37260 b5d04dddd1ac6143201adfa30c25692b 239 SMART SM00382 40 228 8.6E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c25870 4d2f622b37b806beb85bf54a4271aa1c 727 SUPERFAMILY SSF56935 74 727 3.66E-106 T 12-10-2018 MIM_c25870 4d2f622b37b806beb85bf54a4271aa1c 727 Gene3D G3DSA:2.40.170.20 193 727 2.3E-129 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MIM_c25870 4d2f622b37b806beb85bf54a4271aa1c 727 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 87 726 5.6E-99 T 12-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 MIM_c25870 4d2f622b37b806beb85bf54a4271aa1c 727 Pfam PF07715 TonB-dependent Receptor Plug Domain 85 185 5.5E-16 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain MIM_c25870 4d2f622b37b806beb85bf54a4271aa1c 727 Gene3D G3DSA:2.170.130.10 62 192 1.1E-35 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MIM_c25870 4d2f622b37b806beb85bf54a4271aa1c 727 Pfam PF00593 TonB dependent receptor 297 726 1.6E-39 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MIM_c07930 4b42f6c4c9b7b4984fbb9566141520d1 288 TIGRFAM TIGR03132 malonate_mdcB: triphosphoribosyl-dephospho-CoA synthase MdcB 23 287 2.2E-97 T 12-10-2018 IPR017555 Triphosphoribosyl-dephospho-CoA synthase GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 MIM_c07930 4b42f6c4c9b7b4984fbb9566141520d1 288 Hamap MF_01883 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase [mdcB]. 1 288 109.603 T 12-10-2018 IPR017555 Triphosphoribosyl-dephospho-CoA synthase GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 MIM_c07930 4b42f6c4c9b7b4984fbb9566141520d1 288 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 27 285 6.4E-77 T 12-10-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 MIM_c04630 b4cd8741f477a0c8ca689bbd72a058ec 911 Pfam PF00999 Sodium/hydrogen exchanger family 13 413 1.0E-55 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MIM_c04630 b4cd8741f477a0c8ca689bbd72a058ec 911 SMART SM00100 703 817 1.8E-5 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain MIM_c04630 b4cd8741f477a0c8ca689bbd72a058ec 911 Gene3D G3DSA:2.60.120.10 695 828 2.2E-24 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c04630 b4cd8741f477a0c8ca689bbd72a058ec 911 Pfam PF00027 Cyclic nucleotide-binding domain 741 804 6.6E-10 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain MIM_c04630 b4cd8741f477a0c8ca689bbd72a058ec 911 SUPERFAMILY SSF51206 695 821 1.96E-23 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like MIM_c40580 fcc813ef619feb947fb5c8376d8b357d 373 SUPERFAMILY SSF50952 25 371 1.57E-42 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 MIM_c40580 fcc813ef619feb947fb5c8376d8b357d 373 Gene3D G3DSA:2.120.10.30 23 371 3.1E-132 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MIM_c40580 fcc813ef619feb947fb5c8376d8b357d 373 Pfam PF07995 Glucose / Sorbosone dehydrogenase 38 368 1.1E-130 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase MIM_c09360 1c18f666f3a5a4fd7598a69cdfe3ae9e 953 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 6 953 18.27 T 12-10-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MIM_c09360 1c18f666f3a5a4fd7598a69cdfe3ae9e 953 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 145 156 - T 12-10-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MIM_c09360 1c18f666f3a5a4fd7598a69cdfe3ae9e 953 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 586 598 - T 12-10-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MIM_c09360 1c18f666f3a5a4fd7598a69cdfe3ae9e 953 Pfam PF00311 Phosphoenolpyruvate carboxylase 141 953 5.9E-276 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MIM_c09360 1c18f666f3a5a4fd7598a69cdfe3ae9e 953 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 405 425 5.5E-53 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MIM_c09360 1c18f666f3a5a4fd7598a69cdfe3ae9e 953 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 626 655 5.5E-53 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MIM_c09360 1c18f666f3a5a4fd7598a69cdfe3ae9e 953 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 254 269 5.5E-53 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MIM_c09360 1c18f666f3a5a4fd7598a69cdfe3ae9e 953 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 584 604 5.5E-53 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MIM_c09360 1c18f666f3a5a4fd7598a69cdfe3ae9e 953 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 764 790 5.5E-53 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MIM_c09360 1c18f666f3a5a4fd7598a69cdfe3ae9e 953 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 144 157 5.5E-53 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MIM_c09360 1c18f666f3a5a4fd7598a69cdfe3ae9e 953 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 196 212 5.5E-53 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MIM_c09360 1c18f666f3a5a4fd7598a69cdfe3ae9e 953 Gene3D G3DSA:1.20.1440.90 283 408 2.0E-5 T 12-10-2018 MIM_c09360 1c18f666f3a5a4fd7598a69cdfe3ae9e 953 SUPERFAMILY SSF51621 16 953 2.04E-278 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MIM_c21450 efea3876b7c6d4bdff325f641d9b30aa 344 Gene3D G3DSA:3.30.420.40 3 319 9.4E-127 T 12-10-2018 MIM_c21450 efea3876b7c6d4bdff325f641d9b30aa 344 Gene3D G3DSA:3.30.420.40 129 297 9.4E-127 T 12-10-2018 MIM_c21450 efea3876b7c6d4bdff325f641d9b30aa 344 ProSitePatterns PS01016 Glycoprotease family signature. 96 116 - T 12-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 MIM_c21450 efea3876b7c6d4bdff325f641d9b30aa 344 SUPERFAMILY SSF53067 2 121 5.76E-30 T 12-10-2018 MIM_c21450 efea3876b7c6d4bdff325f641d9b30aa 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 4.0E-51 T 12-10-2018 IPR017861 Kae1/TsaD family MIM_c21450 efea3876b7c6d4bdff325f641d9b30aa 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 267 276 4.0E-51 T 12-10-2018 IPR017861 Kae1/TsaD family MIM_c21450 efea3876b7c6d4bdff325f641d9b30aa 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 4.0E-51 T 12-10-2018 IPR017861 Kae1/TsaD family MIM_c21450 efea3876b7c6d4bdff325f641d9b30aa 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 131 143 4.0E-51 T 12-10-2018 IPR017861 Kae1/TsaD family MIM_c21450 efea3876b7c6d4bdff325f641d9b30aa 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 4.0E-51 T 12-10-2018 IPR017861 Kae1/TsaD family MIM_c21450 efea3876b7c6d4bdff325f641d9b30aa 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 154 175 4.0E-51 T 12-10-2018 IPR017861 Kae1/TsaD family MIM_c21450 efea3876b7c6d4bdff325f641d9b30aa 344 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 317 2.1E-133 T 12-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 MIM_c21450 efea3876b7c6d4bdff325f641d9b30aa 344 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 310 7.3E-115 T 12-10-2018 IPR017861 Kae1/TsaD family MIM_c21450 efea3876b7c6d4bdff325f641d9b30aa 344 SUPERFAMILY SSF53067 101 311 3.56E-44 T 12-10-2018 MIM_c21450 efea3876b7c6d4bdff325f641d9b30aa 344 Pfam PF00814 Glycoprotease family 24 310 3.3E-99 T 12-10-2018 IPR000905 Gcp-like domain MIM_c21450 efea3876b7c6d4bdff325f641d9b30aa 344 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 339 63.174 T 12-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 MIM_c31700 577ccb3ad68a00e4fd86b201a6e80328 240 PIRSF PIRSF000005 7 224 2.9E-57 T 12-10-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 MIM_c31700 577ccb3ad68a00e4fd86b201a6e80328 240 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 50 113 3.0E-6 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c31700 577ccb3ad68a00e4fd86b201a6e80328 240 SUPERFAMILY SSF46626 49 118 3.69E-21 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c31700 577ccb3ad68a00e4fd86b201a6e80328 240 Pfam PF00034 Cytochrome c 154 222 1.4E-6 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c31700 577ccb3ad68a00e4fd86b201a6e80328 240 Gene3D G3DSA:1.10.760.10 27 117 5.3E-24 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c31700 577ccb3ad68a00e4fd86b201a6e80328 240 Gene3D G3DSA:1.10.760.10 131 222 1.7E-23 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c31700 577ccb3ad68a00e4fd86b201a6e80328 240 SUPERFAMILY SSF46626 137 222 1.2E-18 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c24270 eb322ea2fc147223fffd57fae89fb481 284 Pfam PF13624 SurA N-terminal domain 20 83 2.2E-7 T 12-10-2018 MIM_c24270 eb322ea2fc147223fffd57fae89fb481 284 SUPERFAMILY SSF109998 21 157 1.26E-21 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily MIM_c24270 eb322ea2fc147223fffd57fae89fb481 284 Gene3D G3DSA:3.10.50.40 120 257 2.1E-31 T 12-10-2018 MIM_c24270 eb322ea2fc147223fffd57fae89fb481 284 SUPERFAMILY SSF54534 119 219 3.99E-29 T 12-10-2018 MIM_c24270 eb322ea2fc147223fffd57fae89fb481 284 Pfam PF00639 PPIC-type PPIASE domain 140 219 4.1E-22 T 12-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 MIM_c24270 eb322ea2fc147223fffd57fae89fb481 284 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 157 178 - T 12-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 MIM_c24270 eb322ea2fc147223fffd57fae89fb481 284 Gene3D G3DSA:1.10.4030.30 19 100 3.6E-8 T 12-10-2018 MIM_c21680 3ffde24f87c6dba5f3586b6df6ee3c02 153 Pfam PF09424 Yqey-like protein 8 151 6.4E-46 T 12-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 MIM_c21680 3ffde24f87c6dba5f3586b6df6ee3c02 153 SUPERFAMILY SSF89095 4 151 1.52E-33 T 12-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 MIM_c21680 3ffde24f87c6dba5f3586b6df6ee3c02 153 Gene3D G3DSA:1.10.10.410 93 151 7.0E-9 T 12-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal MIM_c21680 3ffde24f87c6dba5f3586b6df6ee3c02 153 Gene3D G3DSA:1.10.1510.10 3 92 1.2E-26 T 12-10-2018 MIM_c16610 af595e7ab77220ce086fd8509941f142 352 Gene3D G3DSA:3.90.180.10 22 343 3.5E-89 T 12-10-2018 MIM_c16610 af595e7ab77220ce086fd8509941f142 352 SUPERFAMILY SSF50129 1 184 1.95E-36 T 12-10-2018 IPR011032 GroES-like superfamily MIM_c16610 af595e7ab77220ce086fd8509941f142 352 Gene3D G3DSA:3.40.50.720 159 300 3.5E-89 T 12-10-2018 MIM_c16610 af595e7ab77220ce086fd8509941f142 352 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 71 85 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MIM_c16610 af595e7ab77220ce086fd8509941f142 352 SMART SM00829 8 350 3.8E-4 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MIM_c16610 af595e7ab77220ce086fd8509941f142 352 Pfam PF00107 Zinc-binding dehydrogenase 187 314 2.0E-25 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MIM_c16610 af595e7ab77220ce086fd8509941f142 352 SUPERFAMILY SSF51735 147 319 7.29E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c16610 af595e7ab77220ce086fd8509941f142 352 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 141 3.0E-28 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MIM_24p00130 e77631c2cbf6c8824d77db91e6ac9c70 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 6.1E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_24p00130 e77631c2cbf6c8824d77db91e6ac9c70 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 6.1E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_24p00130 e77631c2cbf6c8824d77db91e6ac9c70 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 6.1E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_24p00130 e77631c2cbf6c8824d77db91e6ac9c70 298 Gene3D G3DSA:3.40.190.10 90 290 3.1E-62 T 12-10-2018 MIM_24p00130 e77631c2cbf6c8824d77db91e6ac9c70 298 SUPERFAMILY SSF53850 88 292 4.03E-43 T 12-10-2018 MIM_24p00130 e77631c2cbf6c8824d77db91e6ac9c70 298 Gene3D G3DSA:1.10.10.10 1 84 2.9E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_24p00130 e77631c2cbf6c8824d77db91e6ac9c70 298 Gene3D G3DSA:3.40.190.10 168 266 3.1E-62 T 12-10-2018 MIM_24p00130 e77631c2cbf6c8824d77db91e6ac9c70 298 SUPERFAMILY SSF46785 3 82 3.16E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_24p00130 e77631c2cbf6c8824d77db91e6ac9c70 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 5.0E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_24p00130 e77631c2cbf6c8824d77db91e6ac9c70 298 Pfam PF03466 LysR substrate binding domain 94 281 1.1E-22 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c37930 77a81e932807862e4efaaa8bbbb565ae 290 Gene3D G3DSA:1.10.3720.10 16 287 3.5E-55 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c37930 77a81e932807862e4efaaa8bbbb565ae 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 278 4.0E-11 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c37930 77a81e932807862e4efaaa8bbbb565ae 290 SUPERFAMILY SSF161098 26 276 1.83E-54 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c12620 2664c7cbf359d73b6529d6be6d0fa173 412 SUPERFAMILY SSF56524 61 328 2.49E-73 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 MIM_c12620 2664c7cbf359d73b6529d6be6d0fa173 412 Gene3D G3DSA:3.90.420.10 39 296 1.1E-93 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 MIM_c12620 2664c7cbf359d73b6529d6be6d0fa173 412 SUPERFAMILY SSF81296 298 410 1.4E-25 T 12-10-2018 IPR014756 Immunoglobulin E-set MIM_c12620 2664c7cbf359d73b6529d6be6d0fa173 412 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 295 403 3.3E-8 T 12-10-2018 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 MIM_c12620 2664c7cbf359d73b6529d6be6d0fa173 412 Pfam PF00174 Oxidoreductase molybdopterin binding domain 99 268 1.0E-51 T 12-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 MIM_c12620 2664c7cbf359d73b6529d6be6d0fa173 412 PRINTS PR00407 Eukaryotic molybdopterin domain signature 231 244 2.0E-12 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 MIM_c12620 2664c7cbf359d73b6529d6be6d0fa173 412 PRINTS PR00407 Eukaryotic molybdopterin domain signature 214 230 2.0E-12 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 MIM_c12620 2664c7cbf359d73b6529d6be6d0fa173 412 PRINTS PR00407 Eukaryotic molybdopterin domain signature 161 176 2.0E-12 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 MIM_c12620 2664c7cbf359d73b6529d6be6d0fa173 412 PRINTS PR00407 Eukaryotic molybdopterin domain signature 334 346 2.0E-12 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 MIM_c12620 2664c7cbf359d73b6529d6be6d0fa173 412 PRINTS PR00407 Eukaryotic molybdopterin domain signature 379 391 2.0E-12 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 MIM_c12620 2664c7cbf359d73b6529d6be6d0fa173 412 PRINTS PR00407 Eukaryotic molybdopterin domain signature 83 99 2.0E-12 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 MIM_c12620 2664c7cbf359d73b6529d6be6d0fa173 412 Gene3D G3DSA:2.60.40.650 297 412 4.4E-31 T 12-10-2018 MIM_c13620 4517042268620201b524fc67085612dc 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 66 1.2E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c13620 4517042268620201b524fc67085612dc 190 Gene3D G3DSA:1.10.357.10 13 188 6.6E-31 T 12-10-2018 MIM_c13620 4517042268620201b524fc67085612dc 190 SUPERFAMILY SSF46689 7 84 3.44E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c13620 4517042268620201b524fc67085612dc 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 6.7E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c13620 4517042268620201b524fc67085612dc 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 6.7E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c30720 0c7b0497e750cc9e170e946769e8d038 325 SUPERFAMILY SSF53850 108 280 4.13E-13 T 12-10-2018 MIM_c30720 0c7b0497e750cc9e170e946769e8d038 325 Gene3D G3DSA:3.40.190.10 126 249 1.2E-109 T 12-10-2018 MIM_c30720 0c7b0497e750cc9e170e946769e8d038 325 PIRSF PIRSF017082 1 325 7.2E-73 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c30720 0c7b0497e750cc9e170e946769e8d038 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 321 2.5E-85 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c30720 0c7b0497e750cc9e170e946769e8d038 325 Gene3D G3DSA:3.40.190.150 28 315 1.2E-109 T 12-10-2018 MIM_c21180 824b6554e643d1601f0f01da9f1ab0c1 163 Pfam PF01899 Na+/H+ ion antiporter subunit 12 161 2.3E-30 T 12-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 MIM_c09890 45676c22b6918c195bc98b6bc9f4c20b 746 Gene3D G3DSA:2.60.40.1760 24 235 1.4E-16 T 12-10-2018 MIM_c09890 45676c22b6918c195bc98b6bc9f4c20b 746 SUPERFAMILY SSF51011 584 663 7.19E-21 T 12-10-2018 MIM_c09890 45676c22b6918c195bc98b6bc9f4c20b 746 Pfam PF01055 Glycosyl hydrolases family 31 231 668 5.8E-61 T 12-10-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 MIM_c09890 45676c22b6918c195bc98b6bc9f4c20b 746 SUPERFAMILY SSF51445 239 582 1.47E-25 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily MIM_c09890 45676c22b6918c195bc98b6bc9f4c20b 746 SUPERFAMILY SSF74650 23 236 2.57E-21 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 MIM_c09890 45676c22b6918c195bc98b6bc9f4c20b 746 Gene3D G3DSA:3.20.20.80 238 614 8.3E-60 T 12-10-2018 MIM_c09890 45676c22b6918c195bc98b6bc9f4c20b 746 Gene3D G3DSA:2.60.40.1180 615 663 1.9E-11 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta MIM_c32480 1a3d02ccf16a58a9e21046975f1da774 275 Gene3D G3DSA:1.10.8.50 135 274 2.1E-42 T 12-10-2018 MIM_c32480 1a3d02ccf16a58a9e21046975f1da774 275 ProSitePatterns PS01242 Zinc finger FPG-type signature. 249 273 - T 12-10-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 MIM_c32480 1a3d02ccf16a58a9e21046975f1da774 275 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 274 38.95 T 12-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 MIM_c32480 1a3d02ccf16a58a9e21046975f1da774 275 SMART SM01232 133 225 2.5E-39 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 MIM_c32480 1a3d02ccf16a58a9e21046975f1da774 275 SUPERFAMILY SSF57716 222 273 1.03E-14 T 12-10-2018 MIM_c32480 1a3d02ccf16a58a9e21046975f1da774 275 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 114 6.2E-28 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MIM_c32480 1a3d02ccf16a58a9e21046975f1da774 275 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 133 222 4.0E-22 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 MIM_c32480 1a3d02ccf16a58a9e21046975f1da774 275 SUPERFAMILY SSF81624 2 142 9.55E-36 T 12-10-2018 IPR035937 MutM-like, N-terminal MIM_c32480 1a3d02ccf16a58a9e21046975f1da774 275 Pfam PF06827 Zinc finger found in FPG and IleRS 247 273 4.0E-11 T 12-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 MIM_c32480 1a3d02ccf16a58a9e21046975f1da774 275 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 273 8.5E-83 T 12-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 MIM_c32480 1a3d02ccf16a58a9e21046975f1da774 275 Gene3D G3DSA:3.20.190.10 2 125 4.4E-33 T 12-10-2018 IPR035937 MutM-like, N-terminal MIM_c32480 1a3d02ccf16a58a9e21046975f1da774 275 SMART SM00898 2 115 3.2E-42 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MIM_c32480 1a3d02ccf16a58a9e21046975f1da774 275 SUPERFAMILY SSF46946 134 225 5.89E-25 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 MIM_c27600 1b6e5f166aa17fa1efd6d41cbd0868bc 562 Gene3D G3DSA:3.30.300.310 443 547 3.9E-24 T 12-10-2018 MIM_c27600 1b6e5f166aa17fa1efd6d41cbd0868bc 562 Pfam PF13193 AMP-binding enzyme C-terminal domain 456 533 1.2E-12 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MIM_c27600 1b6e5f166aa17fa1efd6d41cbd0868bc 562 Gene3D G3DSA:3.40.50.980 28 178 1.2E-36 T 12-10-2018 MIM_c27600 1b6e5f166aa17fa1efd6d41cbd0868bc 562 Pfam PF00501 AMP-binding enzyme 39 446 2.1E-58 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MIM_c27600 1b6e5f166aa17fa1efd6d41cbd0868bc 562 Gene3D G3DSA:2.30.38.10 362 440 1.7E-14 T 12-10-2018 MIM_c27600 1b6e5f166aa17fa1efd6d41cbd0868bc 562 SUPERFAMILY SSF56801 27 546 2.22E-104 T 12-10-2018 MIM_c27600 1b6e5f166aa17fa1efd6d41cbd0868bc 562 Gene3D G3DSA:3.40.50.980 196 356 5.0E-31 T 12-10-2018 MIM_c27600 1b6e5f166aa17fa1efd6d41cbd0868bc 562 ProSitePatterns PS00455 Putative AMP-binding domain signature. 202 213 - T 12-10-2018 IPR020845 AMP-binding, conserved site MIM_c34050 3a5ee7f0763e4cba76672f9b3c00c9a1 149 PIRSF PIRSF001263 1 149 2.1E-49 T 12-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 MIM_c34050 3a5ee7f0763e4cba76672f9b3c00c9a1 149 Pfam PF02560 Cyanate lyase C-terminal domain 81 147 1.8E-35 T 12-10-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00910+4.2.1.104 MIM_c34050 3a5ee7f0763e4cba76672f9b3c00c9a1 149 PRINTS PR01693 Cyanase signature 36 53 4.3E-25 T 12-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 MIM_c34050 3a5ee7f0763e4cba76672f9b3c00c9a1 149 PRINTS PR01693 Cyanase signature 85 99 4.3E-25 T 12-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 MIM_c34050 3a5ee7f0763e4cba76672f9b3c00c9a1 149 PRINTS PR01693 Cyanase signature 134 144 4.3E-25 T 12-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 MIM_c34050 3a5ee7f0763e4cba76672f9b3c00c9a1 149 PRINTS PR01693 Cyanase signature 103 119 4.3E-25 T 12-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 MIM_c34050 3a5ee7f0763e4cba76672f9b3c00c9a1 149 PRINTS PR01693 Cyanase signature 16 31 4.3E-25 T 12-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 MIM_c34050 3a5ee7f0763e4cba76672f9b3c00c9a1 149 TIGRFAM TIGR00673 cynS: cyanase 5 149 1.7E-52 T 12-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 MIM_c34050 3a5ee7f0763e4cba76672f9b3c00c9a1 149 Gene3D G3DSA:3.30.1160.10 83 149 1.8E-34 T 12-10-2018 IPR036581 Cyanate lyase, C-terminal domain superfamily GO:0009439 KEGG: 00910+4.2.1.104 MIM_c34050 3a5ee7f0763e4cba76672f9b3c00c9a1 149 SUPERFAMILY SSF55234 82 149 2.48E-30 T 12-10-2018 IPR036581 Cyanate lyase, C-terminal domain superfamily GO:0009439 KEGG: 00910+4.2.1.104 MIM_c34050 3a5ee7f0763e4cba76672f9b3c00c9a1 149 SMART SM01116 77 149 3.4E-51 T 12-10-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00910+4.2.1.104 MIM_c34050 3a5ee7f0763e4cba76672f9b3c00c9a1 149 Hamap MF_00535 Cyanate hydratase [cynS]. 1 149 81.639 T 12-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 MIM_c34050 3a5ee7f0763e4cba76672f9b3c00c9a1 149 SUPERFAMILY SSF47413 2 79 2.61E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c34050 3a5ee7f0763e4cba76672f9b3c00c9a1 149 Gene3D G3DSA:1.10.260.40 2 82 2.7E-28 T 12-10-2018 MIM_c36110 022070157a16c04569e754d2985e8d88 203 Pfam PF05995 Cysteine dioxygenase type I 75 161 4.1E-7 T 12-10-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 MIM_c36110 022070157a16c04569e754d2985e8d88 203 SUPERFAMILY SSF51182 9 197 6.68E-52 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c36110 022070157a16c04569e754d2985e8d88 203 Gene3D G3DSA:2.60.120.10 47 190 1.2E-50 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c39190 be85fea77f6d29ccbbda105396a61c59 331 Gene3D G3DSA:3.40.190.150 34 321 4.8E-52 T 12-10-2018 MIM_c39190 be85fea77f6d29ccbbda105396a61c59 331 Gene3D G3DSA:3.40.190.10 128 256 4.8E-52 T 12-10-2018 MIM_c39190 be85fea77f6d29ccbbda105396a61c59 331 SUPERFAMILY SSF53850 93 235 2.92E-9 T 12-10-2018 MIM_c39190 be85fea77f6d29ccbbda105396a61c59 331 PIRSF PIRSF017082 1 331 1.4E-72 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c39190 be85fea77f6d29ccbbda105396a61c59 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 74 322 4.7E-18 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c30360 5dbd6947a509e399e2b2040c7a049f02 283 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 218 261 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MIM_c30360 5dbd6947a509e399e2b2040c7a049f02 283 SUPERFAMILY SSF46689 230 269 2.78E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c30360 5dbd6947a509e399e2b2040c7a049f02 283 Pfam PF12833 Helix-turn-helix domain 190 266 5.4E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c30360 5dbd6947a509e399e2b2040c7a049f02 283 SMART SM00342 183 265 2.5E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c30360 5dbd6947a509e399e2b2040c7a049f02 283 Gene3D G3DSA:1.10.10.60 165 276 6.8E-19 T 12-10-2018 MIM_c30360 5dbd6947a509e399e2b2040c7a049f02 283 SUPERFAMILY SSF51182 10 192 4.05E-11 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c30360 5dbd6947a509e399e2b2040c7a049f02 283 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 249 265 1.2E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MIM_c30360 5dbd6947a509e399e2b2040c7a049f02 283 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 234 249 1.2E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MIM_c05160 cfcb6da3c0e27270a938f901abced395 295 Gene3D G3DSA:3.10.310.10 5 277 2.2E-93 T 12-10-2018 MIM_c05160 cfcb6da3c0e27270a938f901abced395 295 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 282 36.195 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MIM_c05160 cfcb6da3c0e27270a938f901abced395 295 Pfam PF01678 Diaminopimelate epimerase 163 274 1.8E-24 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MIM_c05160 cfcb6da3c0e27270a938f901abced395 295 Pfam PF01678 Diaminopimelate epimerase 5 124 3.2E-32 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MIM_c05160 cfcb6da3c0e27270a938f901abced395 295 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 4 280 1.4E-84 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MIM_c05160 cfcb6da3c0e27270a938f901abced395 295 Gene3D G3DSA:3.10.310.10 117 269 2.2E-93 T 12-10-2018 MIM_c05160 cfcb6da3c0e27270a938f901abced395 295 SUPERFAMILY SSF54506 3 282 5.07E-48 T 12-10-2018 MIM_c05160 cfcb6da3c0e27270a938f901abced395 295 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 66 80 - T 12-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MIM_c18680 da1afebd427e054609b35e5b89bea208 355 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 8 353 2.5E-152 T 12-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 MIM_c18680 da1afebd427e054609b35e5b89bea208 355 Gene3D G3DSA:3.30.160.20 216 311 2.7E-97 T 12-10-2018 MIM_c18680 da1afebd427e054609b35e5b89bea208 355 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 355 38.156 T 12-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 MIM_c18680 da1afebd427e054609b35e5b89bea208 355 Gene3D G3DSA:1.20.58.410 2 106 4.5E-24 T 12-10-2018 MIM_c18680 da1afebd427e054609b35e5b89bea208 355 SUPERFAMILY SSF75620 22 352 1.11E-129 T 12-10-2018 MIM_c18680 da1afebd427e054609b35e5b89bea208 355 SMART SM00937 75 185 1.1E-50 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 MIM_c18680 da1afebd427e054609b35e5b89bea208 355 Gene3D G3DSA:3.30.70.1660 120 348 2.7E-97 T 12-10-2018 MIM_c18680 da1afebd427e054609b35e5b89bea208 355 Pfam PF00472 RF-1 domain 219 327 5.1E-41 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MIM_c18680 da1afebd427e054609b35e5b89bea208 355 Pfam PF03462 PCRF domain 21 210 3.2E-54 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 MIM_c18680 da1afebd427e054609b35e5b89bea208 355 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 235 251 - T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MIM_c21080 76744075c6c3ec1455d650064ce516ff 301 Pfam PF03466 LysR substrate binding domain 88 293 3.2E-38 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c21080 76744075c6c3ec1455d650064ce516ff 301 Gene3D G3DSA:3.40.190.10 92 290 3.5E-59 T 12-10-2018 MIM_c21080 76744075c6c3ec1455d650064ce516ff 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 1.6E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c21080 76744075c6c3ec1455d650064ce516ff 301 Gene3D G3DSA:1.10.10.10 1 86 3.8E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c21080 76744075c6c3ec1455d650064ce516ff 301 Gene3D G3DSA:3.40.190.10 163 264 3.5E-59 T 12-10-2018 MIM_c21080 76744075c6c3ec1455d650064ce516ff 301 SUPERFAMILY SSF46785 3 111 7.12E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c21080 76744075c6c3ec1455d650064ce516ff 301 SUPERFAMILY SSF53850 88 293 1.5E-37 T 12-10-2018 MIM_c33090 66236546dcce496ebced2cd44d7eb669 698 Pfam PF09334 tRNA synthetases class I (M) 5 407 1.4E-139 T 12-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c33090 66236546dcce496ebced2cd44d7eb669 698 Hamap MF_00098 Methionine--tRNA ligase [metG]. 3 562 36.868 T 12-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MIM_c33090 66236546dcce496ebced2cd44d7eb669 698 SUPERFAMILY SSF52374 3 397 6.12E-91 T 12-10-2018 MIM_c33090 66236546dcce496ebced2cd44d7eb669 698 Pfam PF01588 Putative tRNA binding domain 598 694 3.8E-22 T 12-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 MIM_c33090 66236546dcce496ebced2cd44d7eb669 698 SUPERFAMILY SSF50249 591 697 4.9E-30 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c33090 66236546dcce496ebced2cd44d7eb669 698 Gene3D G3DSA:3.40.50.620 5 395 2.7E-137 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c33090 66236546dcce496ebced2cd44d7eb669 698 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 581 698 2.6E-39 T 12-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MIM_c33090 66236546dcce496ebced2cd44d7eb669 698 Gene3D G3DSA:2.40.50.140 582 698 3.1E-32 T 12-10-2018 MIM_c33090 66236546dcce496ebced2cd44d7eb669 698 SUPERFAMILY SSF47323 397 606 7.85E-26 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c33090 66236546dcce496ebced2cd44d7eb669 698 SUPERFAMILY SSF57770 139 173 5.62E-12 T 12-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MIM_c33090 66236546dcce496ebced2cd44d7eb669 698 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 551 3.1E-151 T 12-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MIM_c33090 66236546dcce496ebced2cd44d7eb669 698 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 23 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c33090 66236546dcce496ebced2cd44d7eb669 698 PRINTS PR01041 Methionyl-tRNA synthetase signature 301 316 3.2E-22 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MIM_c33090 66236546dcce496ebced2cd44d7eb669 698 PRINTS PR01041 Methionyl-tRNA synthetase signature 395 406 3.2E-22 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MIM_c33090 66236546dcce496ebced2cd44d7eb669 698 PRINTS PR01041 Methionyl-tRNA synthetase signature 7 20 3.2E-22 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MIM_c33090 66236546dcce496ebced2cd44d7eb669 698 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 3.2E-22 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MIM_c33090 66236546dcce496ebced2cd44d7eb669 698 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 3.2E-22 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MIM_c33090 66236546dcce496ebced2cd44d7eb669 698 PRINTS PR01041 Methionyl-tRNA synthetase signature 262 273 3.2E-22 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MIM_c33090 66236546dcce496ebced2cd44d7eb669 698 Gene3D G3DSA:2.20.28.20 139 173 2.7E-137 T 12-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MIM_c33090 66236546dcce496ebced2cd44d7eb669 698 Gene3D G3DSA:1.10.730.10 400 540 6.6E-22 T 12-10-2018 MIM_c02360 7fd7740781b685816b41a88a05a63ab5 432 ProSitePatterns PS00217 Sugar transport proteins signature 2. 125 150 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MIM_c02360 7fd7740781b685816b41a88a05a63ab5 432 SUPERFAMILY SSF103473 9 425 1.57E-59 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c02360 7fd7740781b685816b41a88a05a63ab5 432 Gene3D G3DSA:1.20.1250.20 7 428 1.0E-59 T 12-10-2018 MIM_c02360 7fd7740781b685816b41a88a05a63ab5 432 Pfam PF00083 Sugar (and other) transporter 13 416 4.1E-27 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MIM_c12100 00f280b4116795c8a0b2077b66f3a1a2 394 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 12-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 MIM_c12100 00f280b4116795c8a0b2077b66f3a1a2 394 Pfam PF00108 Thiolase, N-terminal domain 5 268 6.3E-75 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 MIM_c12100 00f280b4116795c8a0b2077b66f3a1a2 394 SUPERFAMILY SSF53901 277 384 2.12E-38 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c12100 00f280b4116795c8a0b2077b66f3a1a2 394 Gene3D G3DSA:3.40.47.10 6 281 7.5E-149 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c12100 00f280b4116795c8a0b2077b66f3a1a2 394 ProSitePatterns PS00737 Thiolases signature 2. 346 362 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 MIM_c12100 00f280b4116795c8a0b2077b66f3a1a2 394 SUPERFAMILY SSF53901 3 275 1.12E-83 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c12100 00f280b4116795c8a0b2077b66f3a1a2 394 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 382 7.7E-130 T 12-10-2018 IPR002155 Thiolase GO:0016747 MIM_c12100 00f280b4116795c8a0b2077b66f3a1a2 394 Gene3D G3DSA:3.40.47.10 141 383 7.5E-149 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c12100 00f280b4116795c8a0b2077b66f3a1a2 394 TIGRFAM TIGR02430 pcaF: 3-oxoadipyl-CoA thiolase 3 386 5.3E-210 T 12-10-2018 IPR012793 Beta-ketoadipyl CoA thiolase GO:0016747|GO:0019619 KEGG: 00360+2.3.1.174|KEGG: 00362+2.3.1.174|MetaCyc: PWY-1361|MetaCyc: PWY-2361|MetaCyc: PWY-6185 MIM_c12100 00f280b4116795c8a0b2077b66f3a1a2 394 Pfam PF02803 Thiolase, C-terminal domain 276 380 5.0E-37 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 MIM_c12100 00f280b4116795c8a0b2077b66f3a1a2 394 PIRSF PIRSF000429 1 386 3.7E-124 T 12-10-2018 IPR002155 Thiolase GO:0016747 MIM_c01400 e070eced67428861a8f88a421e5b1572 341 SUPERFAMILY SSF51735 7 155 3.36E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c01400 e070eced67428861a8f88a421e5b1572 341 SUPERFAMILY SSF55347 134 281 6.21E-12 T 12-10-2018 MIM_c01400 e070eced67428861a8f88a421e5b1572 341 Gene3D G3DSA:3.40.50.720 4 128 4.8E-33 T 12-10-2018 MIM_c01400 e070eced67428861a8f88a421e5b1572 341 Gene3D G3DSA:3.30.360.10 129 340 1.4E-26 T 12-10-2018 MIM_c01400 e070eced67428861a8f88a421e5b1572 341 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 117 1.0E-23 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MIM_c39540 e683484f30ed0ea56a8079f5b06eb0f4 99 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 7 75 1.7E-15 T 12-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM MIM_c39540 e683484f30ed0ea56a8079f5b06eb0f4 99 SUPERFAMILY SSF143120 7 83 1.14E-10 T 12-10-2018 IPR036165 YefM-like superfamily MIM_c39540 e683484f30ed0ea56a8079f5b06eb0f4 99 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 8 48 3.6E-7 T 12-10-2018 MIM_c39540 e683484f30ed0ea56a8079f5b06eb0f4 99 Gene3D G3DSA:3.40.1620.10 1 44 1.2E-7 T 12-10-2018 MIM_c22450 29df2c3d6be992b2cfe4c61fa4bea0b7 142 SUPERFAMILY SSF50331 75 140 1.46E-19 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MIM_c22450 29df2c3d6be992b2cfe4c61fa4bea0b7 142 Gene3D G3DSA:2.40.50.100 1 67 8.0E-25 T 12-10-2018 MIM_c22450 29df2c3d6be992b2cfe4c61fa4bea0b7 142 Gene3D G3DSA:2.40.50.100 74 140 5.7E-23 T 12-10-2018 MIM_c22450 29df2c3d6be992b2cfe4c61fa4bea0b7 142 Pfam PF03459 TOBE domain 76 138 4.3E-15 T 12-10-2018 IPR005116 Transport-associated OB, type 1 MIM_c22450 29df2c3d6be992b2cfe4c61fa4bea0b7 142 Pfam PF03459 TOBE domain 4 64 1.8E-14 T 12-10-2018 IPR005116 Transport-associated OB, type 1 MIM_c22450 29df2c3d6be992b2cfe4c61fa4bea0b7 142 SUPERFAMILY SSF50331 1 69 2.14E-19 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MIM_c22450 29df2c3d6be992b2cfe4c61fa4bea0b7 142 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 1 68 2.7E-19 T 12-10-2018 IPR004606 Molybdenum-pterin binding GO:0015689 MIM_c22450 29df2c3d6be992b2cfe4c61fa4bea0b7 142 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 75 140 8.9E-19 T 12-10-2018 IPR004606 Molybdenum-pterin binding GO:0015689 MIM_c09650 9ad8a7527debab7c8a3846d34ca577e1 353 TIGRFAM TIGR00856 pyrC_dimer: dihydroorotase, homodimeric type 8 351 4.8E-132 T 12-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MIM_c09650 9ad8a7527debab7c8a3846d34ca577e1 353 Pfam PF01979 Amidohydrolase family 15 318 5.9E-19 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MIM_c09650 9ad8a7527debab7c8a3846d34ca577e1 353 ProSitePatterns PS00483 Dihydroorotase signature 2. 254 265 - T 12-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MIM_c09650 9ad8a7527debab7c8a3846d34ca577e1 353 Hamap MF_00219 Dihydroorotase [pyrC]. 6 352 44.955 T 12-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MIM_c09650 9ad8a7527debab7c8a3846d34ca577e1 353 PIRSF PIRSF001237 4 353 2.3E-134 T 12-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MIM_c09650 9ad8a7527debab7c8a3846d34ca577e1 353 Gene3D G3DSA:3.20.20.140 6 352 3.2E-104 T 12-10-2018 MIM_c09650 9ad8a7527debab7c8a3846d34ca577e1 353 SUPERFAMILY SSF51556 7 350 1.8E-137 T 12-10-2018 IPR032466 Metal-dependent hydrolase MIM_c09420 00bd7fabe0520d8ef2f43aa0d1011443 288 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c09420 00bd7fabe0520d8ef2f43aa0d1011443 288 Pfam PF00005 ABC transporter 24 166 2.4E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c09420 00bd7fabe0520d8ef2f43aa0d1011443 288 SUPERFAMILY SSF52540 5 227 2.92E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c09420 00bd7fabe0520d8ef2f43aa0d1011443 288 TIGRFAM TIGR01184 ntrCD: nitrate ABC transporter, ATP-binding proteins C and D 24 254 1.4E-99 T 12-10-2018 IPR005890 Nitrate transport ATP-binding subunit C/D GO:0015112|GO:0015706|GO:0016020 MIM_c09420 00bd7fabe0520d8ef2f43aa0d1011443 288 SMART SM00382 33 216 5.0E-19 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c09420 00bd7fabe0520d8ef2f43aa0d1011443 288 Gene3D G3DSA:3.40.50.300 2 271 1.1E-60 T 12-10-2018 MIM_c13760 39b2832bc121f65332cce6c81c0c676f 402 SUPERFAMILY SSF103473 10 394 4.71E-62 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c13760 39b2832bc121f65332cce6c81c0c676f 402 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 16 392 4.0E-91 T 12-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 MIM_c13760 39b2832bc121f65332cce6c81c0c676f 402 Pfam PF07690 Major Facilitator Superfamily 28 363 1.2E-41 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c13760 39b2832bc121f65332cce6c81c0c676f 402 Gene3D G3DSA:1.20.1720.10 20 395 3.4E-102 T 12-10-2018 MIM_c33480 aa09514f87de964c3755fd20fc4cb3f5 338 Gene3D G3DSA:3.40.50.80 199 331 2.8E-35 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MIM_c33480 aa09514f87de964c3755fd20fc4cb3f5 338 SUPERFAMILY SSF54292 5 87 1.17E-25 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MIM_c33480 aa09514f87de964c3755fd20fc4cb3f5 338 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 80 1.5E-16 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MIM_c33480 aa09514f87de964c3755fd20fc4cb3f5 338 Gene3D G3DSA:2.40.30.10 99 197 4.4E-21 T 12-10-2018 MIM_c33480 aa09514f87de964c3755fd20fc4cb3f5 338 Pfam PF00970 Oxidoreductase FAD-binding domain 104 197 7.6E-12 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 MIM_c33480 aa09514f87de964c3755fd20fc4cb3f5 338 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MIM_c33480 aa09514f87de964c3755fd20fc4cb3f5 338 SUPERFAMILY SSF63380 101 196 2.33E-21 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MIM_c33480 aa09514f87de964c3755fd20fc4cb3f5 338 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 206 225 2.1E-9 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MIM_c33480 aa09514f87de964c3755fd20fc4cb3f5 338 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 243 254 2.1E-9 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MIM_c33480 aa09514f87de964c3755fd20fc4cb3f5 338 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 130 140 2.1E-9 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MIM_c33480 aa09514f87de964c3755fd20fc4cb3f5 338 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 296 304 2.1E-9 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MIM_c33480 aa09514f87de964c3755fd20fc4cb3f5 338 Pfam PF00175 Oxidoreductase NAD-binding domain 209 310 2.1E-25 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MIM_c33480 aa09514f87de964c3755fd20fc4cb3f5 338 SUPERFAMILY SSF52343 200 330 4.06E-39 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MIM_c33480 aa09514f87de964c3755fd20fc4cb3f5 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 206 225 7.9E-17 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MIM_c33480 aa09514f87de964c3755fd20fc4cb3f5 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 146 153 7.9E-17 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MIM_c33480 aa09514f87de964c3755fd20fc4cb3f5 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 231 240 7.9E-17 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MIM_c33480 aa09514f87de964c3755fd20fc4cb3f5 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 190 199 7.9E-17 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MIM_c33480 aa09514f87de964c3755fd20fc4cb3f5 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 130 142 7.9E-17 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MIM_c33480 aa09514f87de964c3755fd20fc4cb3f5 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 296 304 7.9E-17 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MIM_c33480 aa09514f87de964c3755fd20fc4cb3f5 338 Gene3D G3DSA:3.10.20.30 3 91 5.8E-26 T 12-10-2018 IPR012675 Beta-grasp domain superfamily MIM_c39880 07bceaa6b2b86c1397a412488a2b7e6b 305 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 289 9.7E-52 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c23860 e27fb444098b0daedf0a7e7693b0132b 165 SUPERFAMILY SSF89069 12 75 2.48E-12 T 12-10-2018 IPR036147 Anti sigma-E protein RseA, N-terminal domain superfamily GO:0016989 MIM_c23860 e27fb444098b0daedf0a7e7693b0132b 165 Pfam PF03872 Anti sigma-E protein RseA, N-terminal domain 13 82 4.2E-11 T 12-10-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 MIM_c23860 e27fb444098b0daedf0a7e7693b0132b 165 Gene3D G3DSA:1.10.10.880 12 75 1.9E-8 T 12-10-2018 IPR036147 Anti sigma-E protein RseA, N-terminal domain superfamily GO:0016989 MIM_c32470 a544d6d2992ef20d6e80c16b971f0ce5 611 Gene3D G3DSA:1.25.40.10 430 606 2.5E-30 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MIM_c32470 a544d6d2992ef20d6e80c16b971f0ce5 611 SUPERFAMILY SSF48452 172 338 1.06E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MIM_c32470 a544d6d2992ef20d6e80c16b971f0ce5 611 Gene3D G3DSA:1.25.40.10 63 424 8.0E-20 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MIM_c32470 a544d6d2992ef20d6e80c16b971f0ce5 611 Pfam PF14559 Tetratricopeptide repeat 544 601 2.9E-7 T 12-10-2018 MIM_c32470 a544d6d2992ef20d6e80c16b971f0ce5 611 Pfam PF13432 Tetratricopeptide repeat 465 530 6.8E-8 T 12-10-2018 MIM_c32470 a544d6d2992ef20d6e80c16b971f0ce5 611 Pfam PF13432 Tetratricopeptide repeat 287 337 0.011 T 12-10-2018 MIM_c32470 a544d6d2992ef20d6e80c16b971f0ce5 611 SUPERFAMILY SSF48452 434 598 9.76E-24 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MIM_c32470 a544d6d2992ef20d6e80c16b971f0ce5 611 SMART SM00028 310 343 370.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MIM_c32470 a544d6d2992ef20d6e80c16b971f0ce5 611 SMART SM00028 495 529 23.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MIM_c32470 a544d6d2992ef20d6e80c16b971f0ce5 611 SMART SM00028 174 207 21.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MIM_c32470 a544d6d2992ef20d6e80c16b971f0ce5 611 SMART SM00028 461 494 2.4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MIM_c32470 a544d6d2992ef20d6e80c16b971f0ce5 611 SMART SM00028 209 242 280.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MIM_c32470 a544d6d2992ef20d6e80c16b971f0ce5 611 SMART SM00028 563 596 32.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MIM_c21030 3f8ba29b21dd0812cb23ffff79c6acd7 400 Pfam PF00529 HlyD membrane-fusion protein of T1SS 55 378 4.9E-7 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MIM_c21030 3f8ba29b21dd0812cb23ffff79c6acd7 400 Gene3D G3DSA:1.10.287.470 115 188 1.9E-99 T 12-10-2018 MIM_c21030 3f8ba29b21dd0812cb23ffff79c6acd7 400 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 80 310 1.1E-12 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MIM_c21030 3f8ba29b21dd0812cb23ffff79c6acd7 400 Gene3D G3DSA:2.40.420.20 321 390 1.9E-99 T 12-10-2018 MIM_c21030 3f8ba29b21dd0812cb23ffff79c6acd7 400 SUPERFAMILY SSF111369 68 315 3.14E-77 T 12-10-2018 MIM_c21030 3f8ba29b21dd0812cb23ffff79c6acd7 400 Gene3D G3DSA:2.40.30.170 68 320 1.9E-99 T 12-10-2018 MIM_c21030 3f8ba29b21dd0812cb23ffff79c6acd7 400 Gene3D G3DSA:2.40.50.100 80 224 1.9E-99 T 12-10-2018 MIM_c21030 3f8ba29b21dd0812cb23ffff79c6acd7 400 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 56 392 1.0E-76 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MIM_c16380 7a792a2b03daa79f7d6447e18a8d5705 128 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 118 29.288 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c16380 7a792a2b03daa79f7d6447e18a8d5705 128 SUPERFAMILY SSF50104 1 118 1.0E-41 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily MIM_c16380 7a792a2b03daa79f7d6447e18a8d5705 128 Gene3D G3DSA:2.30.30.790 2 122 1.1E-15 T 12-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c16380 7a792a2b03daa79f7d6447e18a8d5705 128 ProSitePatterns PS01015 Ribosomal protein L19 signature. 90 105 - T 12-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c16380 7a792a2b03daa79f7d6447e18a8d5705 128 Pfam PF01245 Ribosomal protein L19 2 117 2.3E-44 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c16380 7a792a2b03daa79f7d6447e18a8d5705 128 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 1 117 3.8E-46 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c16380 7a792a2b03daa79f7d6447e18a8d5705 128 PRINTS PR00061 Ribosomal protein L19 signature 38 67 4.1E-32 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c16380 7a792a2b03daa79f7d6447e18a8d5705 128 PRINTS PR00061 Ribosomal protein L19 signature 92 117 4.1E-32 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c16380 7a792a2b03daa79f7d6447e18a8d5705 128 PRINTS PR00061 Ribosomal protein L19 signature 8 37 4.1E-32 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c16380 7a792a2b03daa79f7d6447e18a8d5705 128 PIRSF PIRSF002191 1 128 2.4E-48 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c22340 4587822465f9c8a8ac88e4719bfa1fe4 227 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 212 7.3E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c22340 4587822465f9c8a8ac88e4719bfa1fe4 227 Gene3D G3DSA:1.10.3720.10 3 216 2.4E-49 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c22340 4587822465f9c8a8ac88e4719bfa1fe4 227 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 111 2.4E-23 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c22340 4587822465f9c8a8ac88e4719bfa1fe4 227 SUPERFAMILY SSF161098 14 208 1.18E-40 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c13120 c9eb1bd673780e81bb1e03c22e42a160 895 ProSitePatterns PS01244 Aconitase family signature 2. 491 504 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MIM_c13120 c9eb1bd673780e81bb1e03c22e42a160 895 ProSitePatterns PS00450 Aconitase family signature 1. 425 441 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MIM_c13120 c9eb1bd673780e81bb1e03c22e42a160 895 PRINTS PR00415 Aconitase family signature 197 210 6.3E-41 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c13120 c9eb1bd673780e81bb1e03c22e42a160 895 PRINTS PR00415 Aconitase family signature 367 381 6.3E-41 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c13120 c9eb1bd673780e81bb1e03c22e42a160 895 PRINTS PR00415 Aconitase family signature 273 286 6.3E-41 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c13120 c9eb1bd673780e81bb1e03c22e42a160 895 PRINTS PR00415 Aconitase family signature 287 300 6.3E-41 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c13120 c9eb1bd673780e81bb1e03c22e42a160 895 PRINTS PR00415 Aconitase family signature 168 176 6.3E-41 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c13120 c9eb1bd673780e81bb1e03c22e42a160 895 PRINTS PR00415 Aconitase family signature 491 504 6.3E-41 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c13120 c9eb1bd673780e81bb1e03c22e42a160 895 PRINTS PR00415 Aconitase family signature 211 226 6.3E-41 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c13120 c9eb1bd673780e81bb1e03c22e42a160 895 PRINTS PR00415 Aconitase family signature 144 157 6.3E-41 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c13120 c9eb1bd673780e81bb1e03c22e42a160 895 PRINTS PR00415 Aconitase family signature 429 440 6.3E-41 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c13120 c9eb1bd673780e81bb1e03c22e42a160 895 Pfam PF00694 Aconitase C-terminal domain 690 822 9.9E-41 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 MIM_c13120 c9eb1bd673780e81bb1e03c22e42a160 895 Gene3D G3DSA:1.10.1440.20 588 649 4.0E-12 T 12-10-2018 MIM_c13120 c9eb1bd673780e81bb1e03c22e42a160 895 SUPERFAMILY SSF53732 5 615 2.75E-215 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 MIM_c13120 c9eb1bd673780e81bb1e03c22e42a160 895 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 16 895 0.0 T 12-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 MIM_c13120 c9eb1bd673780e81bb1e03c22e42a160 895 SUPERFAMILY SSF52016 633 894 7.26E-83 T 12-10-2018 MIM_c13120 c9eb1bd673780e81bb1e03c22e42a160 895 Gene3D G3DSA:3.30.499.10 368 587 2.7E-93 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 MIM_c13120 c9eb1bd673780e81bb1e03c22e42a160 895 Gene3D G3DSA:3.30.499.20 2 367 2.9E-159 T 12-10-2018 MIM_c13120 c9eb1bd673780e81bb1e03c22e42a160 895 Gene3D G3DSA:3.20.19.10 651 895 5.6E-105 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 MIM_c13120 c9eb1bd673780e81bb1e03c22e42a160 895 Pfam PF00330 Aconitase family (aconitate hydratase) 67 560 9.3E-179 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c31400 9c96c47bbdd8dea8de0489375c4205ef 195 Pfam PF05995 Cysteine dioxygenase type I 52 161 2.4E-8 T 12-10-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 MIM_c31400 9c96c47bbdd8dea8de0489375c4205ef 195 Gene3D G3DSA:1.20.5.440 4 46 3.0E-5 T 12-10-2018 MIM_c31400 9c96c47bbdd8dea8de0489375c4205ef 195 Gene3D G3DSA:2.60.120.10 47 189 4.3E-54 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c31400 9c96c47bbdd8dea8de0489375c4205ef 195 SUPERFAMILY SSF51182 7 188 4.7E-54 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c18280 b937e6990b68c9faea3de831e9726566 386 Gene3D G3DSA:3.40.50.261 240 386 1.9E-58 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c18280 b937e6990b68c9faea3de831e9726566 386 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 44.185 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MIM_c18280 b937e6990b68c9faea3de831e9726566 386 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 12-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c18280 b937e6990b68c9faea3de831e9726566 386 Gene3D G3DSA:3.30.1490.20 21 104 2.4E-95 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MIM_c18280 b937e6990b68c9faea3de831e9726566 386 Pfam PF08442 ATP-grasp domain 2 202 3.7E-80 T 12-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MIM_c18280 b937e6990b68c9faea3de831e9726566 386 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 2.4E-160 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MIM_c18280 b937e6990b68c9faea3de831e9726566 386 SUPERFAMILY SSF52210 239 385 9.29E-55 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c18280 b937e6990b68c9faea3de831e9726566 386 SUPERFAMILY SSF56059 1 238 9.37E-85 T 12-10-2018 MIM_c18280 b937e6990b68c9faea3de831e9726566 386 Gene3D G3DSA:3.30.470.20 1 234 2.4E-95 T 12-10-2018 MIM_c18280 b937e6990b68c9faea3de831e9726566 386 PIRSF PIRSF001554 1 386 7.4E-154 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MIM_c18280 b937e6990b68c9faea3de831e9726566 386 Pfam PF00549 CoA-ligase 262 382 7.5E-26 T 12-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MIM_c17580 128d3f474625a0556ab889b1ba3b30de 225 SUPERFAMILY SSF56529 15 220 1.57E-42 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MIM_c17580 128d3f474625a0556ab889b1ba3b30de 225 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 17 220 9.3E-34 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 MIM_c17580 128d3f474625a0556ab889b1ba3b30de 225 Gene3D G3DSA:3.90.850.10 14 224 1.3E-41 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MIM_c39590 fe40123b27c8e76bfc4007bc65ea6d23 455 Gene3D G3DSA:1.10.45.10 414 453 3.8E-7 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 MIM_c39590 fe40123b27c8e76bfc4007bc65ea6d23 455 Pfam PF02913 FAD linked oxidases, C-terminal domain 213 451 9.9E-37 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 MIM_c39590 fe40123b27c8e76bfc4007bc65ea6d23 455 Gene3D G3DSA:3.30.465.40 12 217 1.6E-67 T 12-10-2018 MIM_c39590 fe40123b27c8e76bfc4007bc65ea6d23 455 SUPERFAMILY SSF55103 187 453 1.47E-44 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MIM_c39590 fe40123b27c8e76bfc4007bc65ea6d23 455 Gene3D G3DSA:3.30.70.2190 218 330 1.6E-24 T 12-10-2018 MIM_c39590 fe40123b27c8e76bfc4007bc65ea6d23 455 Pfam PF01565 FAD binding domain 37 174 1.2E-37 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MIM_c39590 fe40123b27c8e76bfc4007bc65ea6d23 455 SUPERFAMILY SSF56176 8 213 3.6E-70 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MIM_c39590 fe40123b27c8e76bfc4007bc65ea6d23 455 Gene3D G3DSA:3.30.70.2740 335 413 5.9E-18 T 12-10-2018 MIM_c14730 ad003f20c8709637d25a2436caca1529 222 Gene3D G3DSA:3.40.50.450 10 218 9.9E-64 T 12-10-2018 MIM_c14730 ad003f20c8709637d25a2436caca1529 222 Pfam PF03641 Possible lysine decarboxylase 75 205 8.4E-34 T 12-10-2018 IPR031100 LOG family MIM_c14730 ad003f20c8709637d25a2436caca1529 222 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 33 207 1.8E-45 T 12-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG MIM_c14730 ad003f20c8709637d25a2436caca1529 222 SUPERFAMILY SSF102405 16 206 1.22E-56 T 12-10-2018 MIM_c19910 a6fc960acfaca1d6020e79f18c0af608 223 SUPERFAMILY SSF89562 26 179 1.12E-38 T 12-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily MIM_c19910 a6fc960acfaca1d6020e79f18c0af608 223 Pfam PF03737 Aldolase/RraA 36 171 4.7E-31 T 12-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MIM_c19910 a6fc960acfaca1d6020e79f18c0af608 223 Gene3D G3DSA:3.50.30.100 8 194 4.0E-42 T 12-10-2018 MIM_c33640 9c2cb278333c844595854b058d1aceaf 300 SUPERFAMILY SSF46785 4 114 9.91E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c33640 9c2cb278333c844595854b058d1aceaf 300 Gene3D G3DSA:3.40.190.10 94 278 1.4E-20 T 12-10-2018 MIM_c33640 9c2cb278333c844595854b058d1aceaf 300 Gene3D G3DSA:1.10.10.10 4 93 1.0E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c33640 9c2cb278333c844595854b058d1aceaf 300 Gene3D G3DSA:3.40.190.10 164 254 1.4E-20 T 12-10-2018 MIM_c33640 9c2cb278333c844595854b058d1aceaf 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 6.0E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c33640 9c2cb278333c844595854b058d1aceaf 300 SUPERFAMILY SSF53850 90 284 4.03E-26 T 12-10-2018 MIM_c33640 9c2cb278333c844595854b058d1aceaf 300 Pfam PF03466 LysR substrate binding domain 90 282 8.1E-23 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c03270 169f5c526fcc64a09fc6093dbafd9d42 675 Pfam PF02785 Biotin carboxylase C-terminal domain 336 447 2.1E-38 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MIM_c03270 169f5c526fcc64a09fc6093dbafd9d42 675 SUPERFAMILY SSF51230 599 673 5.5E-22 T 12-10-2018 IPR011053 Single hybrid motif MIM_c03270 169f5c526fcc64a09fc6093dbafd9d42 675 SUPERFAMILY SSF56059 83 346 2.12E-71 T 12-10-2018 MIM_c03270 169f5c526fcc64a09fc6093dbafd9d42 675 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 322 4.8E-80 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MIM_c03270 169f5c526fcc64a09fc6093dbafd9d42 675 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 3.4E-42 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MIM_c03270 169f5c526fcc64a09fc6093dbafd9d42 675 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 629 646 - T 12-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MIM_c03270 169f5c526fcc64a09fc6093dbafd9d42 675 Gene3D G3DSA:2.40.50.100 608 674 2.8E-24 T 12-10-2018 MIM_c03270 169f5c526fcc64a09fc6093dbafd9d42 675 Gene3D G3DSA:3.30.470.130 1 454 4.5E-204 T 12-10-2018 MIM_c03270 169f5c526fcc64a09fc6093dbafd9d42 675 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MIM_c03270 169f5c526fcc64a09fc6093dbafd9d42 675 SUPERFAMILY SSF51246 331 453 4.34E-41 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MIM_c03270 169f5c526fcc64a09fc6093dbafd9d42 675 SMART SM01209 114 293 0.0011 T 12-10-2018 MIM_c03270 169f5c526fcc64a09fc6093dbafd9d42 675 SMART SM00878 336 447 5.6E-59 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MIM_c03270 169f5c526fcc64a09fc6093dbafd9d42 675 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MIM_c03270 169f5c526fcc64a09fc6093dbafd9d42 675 SUPERFAMILY SSF52440 1 113 3.31E-45 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MIM_c03270 169f5c526fcc64a09fc6093dbafd9d42 675 Pfam PF00364 Biotin-requiring enzyme 607 672 2.0E-18 T 12-10-2018 IPR000089 Biotin/lipoyl attachment MIM_c18770 e3a01519f24e9dfb908cd727526ecf33 806 Pfam PF00753 Metallo-beta-lactamase superfamily 540 649 2.0E-9 T 12-10-2018 IPR001279 Metallo-beta-lactamase MIM_c18770 e3a01519f24e9dfb908cd727526ecf33 806 SMART SM00849 543 743 9.4E-6 T 12-10-2018 IPR001279 Metallo-beta-lactamase MIM_c18770 e3a01519f24e9dfb908cd727526ecf33 806 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 241 429 3.4E-21 T 12-10-2018 IPR004477 ComEC/Rec2-related protein MIM_c18770 e3a01519f24e9dfb908cd727526ecf33 806 SUPERFAMILY SSF56281 531 801 1.9E-42 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MIM_c18770 e3a01519f24e9dfb908cd727526ecf33 806 Gene3D G3DSA:3.60.15.10 536 790 6.4E-51 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MIM_c18770 e3a01519f24e9dfb908cd727526ecf33 806 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 136 778 2.6E-94 T 12-10-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 MIM_c18770 e3a01519f24e9dfb908cd727526ecf33 806 Pfam PF03772 Competence protein 220 506 5.8E-53 T 12-10-2018 IPR004477 ComEC/Rec2-related protein MIM_c18770 e3a01519f24e9dfb908cd727526ecf33 806 Pfam PF13567 Domain of unknown function (DUF4131) 30 177 4.7E-19 T 12-10-2018 IPR025405 Domain of unknown function DUF4131 MIM_c10380 be25e7ac5475ad0bdb29c3641233ea71 250 SUPERFAMILY SSF55729 85 238 1.47E-22 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c10380 be25e7ac5475ad0bdb29c3641233ea71 250 PIRSF PIRSF037208 4 248 3.1E-87 T 12-10-2018 IPR017138 Aspartate/glutamate leucyltransferase GO:0008914|GO:0071596 MetaCyc: PWY-7802 MIM_c10380 be25e7ac5475ad0bdb29c3641233ea71 250 Hamap MF_00689 Aspartate/glutamate leucyltransferase [bpt]. 10 237 39.165 T 12-10-2018 IPR017138 Aspartate/glutamate leucyltransferase GO:0008914|GO:0071596 MetaCyc: PWY-7802 MIM_c10380 be25e7ac5475ad0bdb29c3641233ea71 250 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 111 231 2.4E-36 T 12-10-2018 IPR007472 N-end rule aminoacyl transferase, C-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7802 MIM_c10380 be25e7ac5475ad0bdb29c3641233ea71 250 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 20 90 5.9E-18 T 12-10-2018 IPR007471 N-end aminoacyl transferase, N-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7802 MIM_c03460 9b4ba22fbee29e47f4b5b12c49f0c466 255 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 63 4.1E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c03460 9b4ba22fbee29e47f4b5b12c49f0c466 255 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 63 79 4.1E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c03460 9b4ba22fbee29e47f4b5b12c49f0c466 255 Pfam PF00392 Bacterial regulatory proteins, gntR family 27 89 2.7E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c03460 9b4ba22fbee29e47f4b5b12c49f0c466 255 SMART SM00866 110 249 1.1E-13 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MIM_c03460 9b4ba22fbee29e47f4b5b12c49f0c466 255 Pfam PF07702 UTRA domain 129 248 7.7E-16 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MIM_c03460 9b4ba22fbee29e47f4b5b12c49f0c466 255 SUPERFAMILY SSF64288 78 254 3.14E-25 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MIM_c03460 9b4ba22fbee29e47f4b5b12c49f0c466 255 SUPERFAMILY SSF46785 23 102 1.78E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c03460 9b4ba22fbee29e47f4b5b12c49f0c466 255 Gene3D G3DSA:1.10.10.10 24 112 8.2E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c03460 9b4ba22fbee29e47f4b5b12c49f0c466 255 Gene3D G3DSA:3.40.1410.10 115 255 2.0E-21 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MIM_c03460 9b4ba22fbee29e47f4b5b12c49f0c466 255 SMART SM00345 30 89 7.5E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c22250 73f737e354aa6b364ef811404b0ef2d7 286 SUPERFAMILY SSF74653 204 285 1.83E-20 T 12-10-2018 MIM_c22250 73f737e354aa6b364ef811404b0ef2d7 286 PRINTS PR01374 Gram-negative bacterial tonB protein signature 205 226 3.6E-11 T 12-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 MIM_c22250 73f737e354aa6b364ef811404b0ef2d7 286 PRINTS PR01374 Gram-negative bacterial tonB protein signature 139 149 3.6E-11 T 12-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 MIM_c22250 73f737e354aa6b364ef811404b0ef2d7 286 PRINTS PR01374 Gram-negative bacterial tonB protein signature 226 244 3.6E-11 T 12-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 MIM_c22250 73f737e354aa6b364ef811404b0ef2d7 286 PRINTS PR01374 Gram-negative bacterial tonB protein signature 245 262 3.6E-11 T 12-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 MIM_c22250 73f737e354aa6b364ef811404b0ef2d7 286 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 211 285 2.3E-18 T 12-10-2018 IPR006260 TonB/TolA, C-terminal MIM_c22250 73f737e354aa6b364ef811404b0ef2d7 286 Gene3D G3DSA:3.30.1150.10 194 286 4.1E-19 T 12-10-2018 MIM_c22250 73f737e354aa6b364ef811404b0ef2d7 286 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 209 285 1.2E-20 T 12-10-2018 IPR037682 TonB, C-terminal GO:0055085 MIM_c02750 0ae958e6f6d312f5daeb3978e8603d84 254 Pfam PF00149 Calcineurin-like phosphoesterase 6 198 3.9E-11 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MIM_c02750 0ae958e6f6d312f5daeb3978e8603d84 254 SUPERFAMILY SSF56300 5 200 5.26E-20 T 12-10-2018 MIM_c39040 e7852540f4e92b71f0d489f0156c2409 177 PIRSF PIRSF002162 1 177 5.5E-48 T 12-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39040 e7852540f4e92b71f0d489f0156c2409 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 1.9E-73 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MIM_c39040 e7852540f4e92b71f0d489f0156c2409 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 35.41 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MIM_c39040 e7852540f4e92b71f0d489f0156c2409 177 Gene3D G3DSA:3.90.930.12 1 82 4.1E-29 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39040 e7852540f4e92b71f0d489f0156c2409 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 12-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c39040 e7852540f4e92b71f0d489f0156c2409 177 SUPERFAMILY SSF56053 83 177 3.8E-34 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39040 e7852540f4e92b71f0d489f0156c2409 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 4.8E-32 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MIM_c39040 e7852540f4e92b71f0d489f0156c2409 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 4.8E-32 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MIM_c39040 e7852540f4e92b71f0d489f0156c2409 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 4.8E-32 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MIM_c39040 e7852540f4e92b71f0d489f0156c2409 177 Pfam PF00347 Ribosomal protein L6 90 164 7.2E-17 T 12-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39040 e7852540f4e92b71f0d489f0156c2409 177 Pfam PF00347 Ribosomal protein L6 11 82 4.5E-17 T 12-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39040 e7852540f4e92b71f0d489f0156c2409 177 SUPERFAMILY SSF56053 1 82 1.83E-25 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39040 e7852540f4e92b71f0d489f0156c2409 177 Gene3D G3DSA:3.90.930.12 83 177 3.2E-38 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c01690 60768b6fac473dea67f841ed63101f95 463 Gene3D G3DSA:1.20.1250.20 15 444 1.1E-77 T 12-10-2018 MIM_c01690 60768b6fac473dea67f841ed63101f95 463 Pfam PF00083 Sugar (and other) transporter 56 443 2.9E-39 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MIM_c01690 60768b6fac473dea67f841ed63101f95 463 SUPERFAMILY SSF103473 8 443 1.31E-75 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c15500 7eff98733aeb7982b8299c72046c6e11 360 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 3 241 7.6E-120 T 12-10-2018 IPR005666 Sulphate transport system permease protein 1 GO:0008272|GO:0015419|GO:0016020|GO:0043190 KEGG: 00920+3.6.3.25 MIM_c15500 7eff98733aeb7982b8299c72046c6e11 360 Gene3D G3DSA:3.40.50.300 1 241 2.4E-77 T 12-10-2018 MIM_c15500 7eff98733aeb7982b8299c72046c6e11 360 SUPERFAMILY SSF50331 239 350 3.4E-14 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MIM_c15500 7eff98733aeb7982b8299c72046c6e11 360 Pfam PF12857 TOBE-like domain 296 346 6.5E-17 T 12-10-2018 IPR024765 TOBE-like domain KEGG: 00920+3.6.3.25 MIM_c15500 7eff98733aeb7982b8299c72046c6e11 360 Gene3D G3DSA:2.40.50.100 279 343 3.3E-7 T 12-10-2018 MIM_c15500 7eff98733aeb7982b8299c72046c6e11 360 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c15500 7eff98733aeb7982b8299c72046c6e11 360 Pfam PF00005 ABC transporter 18 164 2.7E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c15500 7eff98733aeb7982b8299c72046c6e11 360 SMART SM00382 27 214 6.1E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c15500 7eff98733aeb7982b8299c72046c6e11 360 Gene3D G3DSA:2.40.50.140 269 278 3.3E-7 T 12-10-2018 MIM_c15500 7eff98733aeb7982b8299c72046c6e11 360 SUPERFAMILY SSF52540 3 247 4.09E-86 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c14210 cab5c10c93fd006dc60b6fa2424f22a4 451 Gene3D G3DSA:3.40.190.10 58 392 1.1E-75 T 12-10-2018 MIM_c14210 cab5c10c93fd006dc60b6fa2424f22a4 451 SUPERFAMILY SSF53850 41 438 5.22E-66 T 12-10-2018 MIM_c14210 cab5c10c93fd006dc60b6fa2424f22a4 451 Gene3D G3DSA:3.40.190.10 163 435 1.1E-75 T 12-10-2018 MIM_c14210 cab5c10c93fd006dc60b6fa2424f22a4 451 Pfam PF01547 Bacterial extracellular solute-binding protein 58 348 1.8E-31 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein MIM_c23100 936dd86ac0d9c540d8e7b9f8863160b2 569 PIRSF PIRSF006429 15 537 2.5E-161 T 12-10-2018 IPR024188 Glutamate synthase large subunit-like protein MIM_c23100 936dd86ac0d9c540d8e7b9f8863160b2 569 PIRSF PIRSF500060 12 532 9.2E-235 T 12-10-2018 IPR027283 Glutamate synthase large subunit-like protein, bacteria MIM_c23100 936dd86ac0d9c540d8e7b9f8863160b2 569 SUPERFAMILY SSF51395 21 502 3.98E-139 T 12-10-2018 MIM_c23100 936dd86ac0d9c540d8e7b9f8863160b2 569 Pfam PF01645 Conserved region in glutamate synthase 158 475 1.7E-86 T 12-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 MIM_c23100 936dd86ac0d9c540d8e7b9f8863160b2 569 Gene3D G3DSA:3.20.20.70 131 502 1.1E-110 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c16270 ee3155430cd73ca37b8c6cb8e69dba50 514 Pfam PF00263 Bacterial type II and III secretion system protein 240 395 8.8E-44 T 12-10-2018 IPR004846 Type II/III secretion system GO:0009306 MIM_c16270 ee3155430cd73ca37b8c6cb8e69dba50 514 PRINTS PR00811 Bacterial general secretion pathway protein D signature 360 378 4.4E-14 T 12-10-2018 IPR001775 GspD/PilQ family MIM_c16270 ee3155430cd73ca37b8c6cb8e69dba50 514 PRINTS PR00811 Bacterial general secretion pathway protein D signature 235 259 4.4E-14 T 12-10-2018 IPR001775 GspD/PilQ family MIM_c16270 ee3155430cd73ca37b8c6cb8e69dba50 514 PRINTS PR00811 Bacterial general secretion pathway protein D signature 270 280 4.4E-14 T 12-10-2018 IPR001775 GspD/PilQ family MIM_c16270 ee3155430cd73ca37b8c6cb8e69dba50 514 PRINTS PR00811 Bacterial general secretion pathway protein D signature 163 173 4.4E-14 T 12-10-2018 IPR001775 GspD/PilQ family MIM_c16270 ee3155430cd73ca37b8c6cb8e69dba50 514 PRINTS PR00811 Bacterial general secretion pathway protein D signature 383 397 4.4E-14 T 12-10-2018 IPR001775 GspD/PilQ family MIM_c16270 ee3155430cd73ca37b8c6cb8e69dba50 514 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 341 374 - T 12-10-2018 IPR004845 Type II secretion system GspD, conserved site GO:0008565 MIM_c16270 ee3155430cd73ca37b8c6cb8e69dba50 514 Pfam PF13629 Pilus formation protein N terminal region 30 95 1.2E-12 T 12-10-2018 IPR032789 Pilus formation protein, N-terminal MIM_c36070 cb01037bd265a520c08bfabc0bbd8671 113 Gene3D G3DSA:1.20.1290.10 3 113 2.9E-30 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c36070 cb01037bd265a520c08bfabc0bbd8671 113 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 43 89 1.3E-17 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c36070 cb01037bd265a520c08bfabc0bbd8671 113 SUPERFAMILY SSF69118 15 112 4.71E-27 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c36070 cb01037bd265a520c08bfabc0bbd8671 113 Pfam PF02627 Carboxymuconolactone decarboxylase family 24 106 8.5E-19 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c07960 7ce9e43a3df8458760a6399086460da0 304 TIGRFAM TIGR03133 malonate_beta: biotin-independent malonate decarboxylase, beta subunit 13 279 1.2E-112 T 12-10-2018 IPR017556 Biotin-independent malonate decarboxylase, beta subunit GO:0016831|GO:0044262 MetaCyc: PWY-6060 MIM_c07960 7ce9e43a3df8458760a6399086460da0 304 Pfam PF01039 Carboxyl transferase domain 17 223 1.2E-18 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 MIM_c07960 7ce9e43a3df8458760a6399086460da0 304 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 182 193 5.6E-6 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MIM_c07960 7ce9e43a3df8458760a6399086460da0 304 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 115 133 5.6E-6 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MIM_c07960 7ce9e43a3df8458760a6399086460da0 304 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 80 94 5.6E-6 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MIM_c07960 7ce9e43a3df8458760a6399086460da0 304 Gene3D G3DSA:3.90.226.10 1 227 4.5E-47 T 12-10-2018 MIM_c07960 7ce9e43a3df8458760a6399086460da0 304 SUPERFAMILY SSF52096 4 240 7.18E-38 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c00630 e27b9d66329b213588acce72d56a0cf7 542 SUPERFAMILY SSF51294 202 317 2.94E-15 T 12-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MIM_c00630 e27b9d66329b213588acce72d56a0cf7 542 Pfam PF13403 Hint domain 203 339 1.1E-43 T 12-10-2018 IPR028992 Hedgehog/Intein (Hint) domain MIM_c36420 03df9d2d23c2b69dee01f3570fc5af5b 331 SUPERFAMILY SSF53807 26 328 4.12E-85 T 12-10-2018 MIM_c36420 03df9d2d23c2b69dee01f3570fc5af5b 331 Gene3D G3DSA:3.40.50.1980 209 330 3.8E-42 T 12-10-2018 MIM_c36420 03df9d2d23c2b69dee01f3570fc5af5b 331 Pfam PF01297 Zinc-uptake complex component A periplasmic 29 327 1.3E-81 T 12-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 MIM_c36420 03df9d2d23c2b69dee01f3570fc5af5b 331 PRINTS PR00690 Adhesin family signature 26 44 3.9E-9 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 MIM_c36420 03df9d2d23c2b69dee01f3570fc5af5b 331 PRINTS PR00690 Adhesin family signature 70 87 3.9E-9 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 MIM_c36420 03df9d2d23c2b69dee01f3570fc5af5b 331 PRINTS PR00690 Adhesin family signature 57 70 3.9E-9 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 MIM_c36420 03df9d2d23c2b69dee01f3570fc5af5b 331 Gene3D G3DSA:3.40.50.1980 137 208 1.7E-20 T 12-10-2018 MIM_c36420 03df9d2d23c2b69dee01f3570fc5af5b 331 PRINTS PR00691 Adhesin B signature 70 89 5.4E-12 T 12-10-2018 IPR006129 Adhesin B GO:0007155 MIM_c36420 03df9d2d23c2b69dee01f3570fc5af5b 331 PRINTS PR00691 Adhesin B signature 51 69 5.4E-12 T 12-10-2018 IPR006129 Adhesin B GO:0007155 MIM_c36420 03df9d2d23c2b69dee01f3570fc5af5b 331 PRINTS PR00691 Adhesin B signature 26 47 5.4E-12 T 12-10-2018 IPR006129 Adhesin B GO:0007155 MIM_c36420 03df9d2d23c2b69dee01f3570fc5af5b 331 Gene3D G3DSA:3.40.50.1980 27 136 2.4E-30 T 12-10-2018 MIM_c31760 d68f767e5afbfab85304cff6a4f6bd1f 253 Pfam PF03737 Aldolase/RraA 52 209 2.4E-28 T 12-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MIM_c31760 d68f767e5afbfab85304cff6a4f6bd1f 253 Gene3D G3DSA:3.50.30.100 12 233 1.9E-73 T 12-10-2018 MIM_c31760 d68f767e5afbfab85304cff6a4f6bd1f 253 SUPERFAMILY SSF89562 50 220 1.01E-32 T 12-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily MIM_c23660 d1087efab1d1d4231eb6a71c990c0915 427 Gene3D G3DSA:3.40.47.10 128 424 6.5E-122 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c23660 d1087efab1d1d4231eb6a71c990c0915 427 ProSitePatterns PS00737 Thiolases signature 2. 372 388 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 MIM_c23660 d1087efab1d1d4231eb6a71c990c0915 427 Gene3D G3DSA:3.40.47.10 8 293 6.5E-122 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c23660 d1087efab1d1d4231eb6a71c990c0915 427 PIRSF PIRSF000429 1 427 2.6E-128 T 12-10-2018 IPR002155 Thiolase GO:0016747 MIM_c23660 d1087efab1d1d4231eb6a71c990c0915 427 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 8 424 2.6E-126 T 12-10-2018 IPR002155 Thiolase GO:0016747 MIM_c23660 d1087efab1d1d4231eb6a71c990c0915 427 Pfam PF02803 Thiolase, C-terminal domain 288 424 5.2E-42 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 MIM_c23660 d1087efab1d1d4231eb6a71c990c0915 427 ProSitePatterns PS00099 Thiolases active site. 407 420 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 MIM_c23660 d1087efab1d1d4231eb6a71c990c0915 427 SUPERFAMILY SSF53901 288 424 1.03E-37 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c23660 d1087efab1d1d4231eb6a71c990c0915 427 Pfam PF00108 Thiolase, N-terminal domain 6 280 3.1E-58 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 MIM_c23660 d1087efab1d1d4231eb6a71c990c0915 427 SUPERFAMILY SSF53901 6 287 5.53E-60 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c07570 4c355dc754edea7a10e840558624a27f 331 Gene3D G3DSA:3.40.190.150 36 321 1.0E-117 T 12-10-2018 MIM_c07570 4c355dc754edea7a10e840558624a27f 331 Gene3D G3DSA:3.40.190.10 133 256 1.0E-117 T 12-10-2018 MIM_c07570 4c355dc754edea7a10e840558624a27f 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 55 327 8.4E-94 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c07570 4c355dc754edea7a10e840558624a27f 331 SUPERFAMILY SSF53850 119 289 3.26E-14 T 12-10-2018 MIM_c07570 4c355dc754edea7a10e840558624a27f 331 PIRSF PIRSF017082 3 331 2.2E-94 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c35860 1af6bc078b7e1925690ae857579bfc24 217 Pfam PF01614 Bacterial transcriptional regulator 91 215 4.0E-42 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal MIM_c35860 1af6bc078b7e1925690ae857579bfc24 217 SUPERFAMILY SSF55781 39 216 2.35E-38 T 12-10-2018 MIM_c35860 1af6bc078b7e1925690ae857579bfc24 217 Gene3D G3DSA:3.30.450.40 38 217 5.1E-48 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c37400 fee6e40b7e42e2ebe36086ce55a71e93 461 TIGRFAM TIGR00797 matE: MATE efflux family protein 16 430 3.7E-52 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MIM_c37400 fee6e40b7e42e2ebe36086ce55a71e93 461 Pfam PF01554 MatE 16 177 2.3E-15 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MIM_c37400 fee6e40b7e42e2ebe36086ce55a71e93 461 Pfam PF01554 MatE 251 415 3.9E-20 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MIM_c35570 2883e821af541a10a9611703d2206ddf 475 SUPERFAMILY SSF53720 4 470 4.45E-149 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c35570 2883e821af541a10a9611703d2206ddf 475 Gene3D G3DSA:3.40.309.10 249 440 5.5E-156 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MIM_c35570 2883e821af541a10a9611703d2206ddf 475 Pfam PF00171 Aldehyde dehydrogenase family 13 469 2.9E-148 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c35570 2883e821af541a10a9611703d2206ddf 475 Gene3D G3DSA:3.40.605.10 9 468 5.5E-156 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c20250 bb580d9ad01c1a337736dd8713eb9835 235 Pfam PF00005 ABC transporter 21 163 5.0E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c20250 bb580d9ad01c1a337736dd8713eb9835 235 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c20250 bb580d9ad01c1a337736dd8713eb9835 235 Gene3D G3DSA:3.40.50.300 1 235 2.5E-57 T 12-10-2018 MIM_c20250 bb580d9ad01c1a337736dd8713eb9835 235 SUPERFAMILY SSF52540 5 232 1.03E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c20250 bb580d9ad01c1a337736dd8713eb9835 235 SMART SM00382 30 211 1.6E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c06620 cae7573cb1621a45074cac079b37ab21 597 Gene3D G3DSA:3.30.930.10 118 589 1.5E-196 T 12-10-2018 MIM_c06620 cae7573cb1621a45074cac079b37ab21 597 Gene3D G3DSA:2.40.50.140 1 105 8.8E-33 T 12-10-2018 MIM_c06620 cae7573cb1621a45074cac079b37ab21 597 Pfam PF00152 tRNA synthetases class II (D, K and N) 119 565 4.6E-108 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c06620 cae7573cb1621a45074cac079b37ab21 597 Pfam PF01336 OB-fold nucleic acid binding domain 18 102 3.3E-19 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MIM_c06620 cae7573cb1621a45074cac079b37ab21 597 PRINTS PR01042 Aspartyl-tRNA synthetase signature 525 539 1.1E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c06620 cae7573cb1621a45074cac079b37ab21 597 PRINTS PR01042 Aspartyl-tRNA synthetase signature 208 221 1.1E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c06620 cae7573cb1621a45074cac079b37ab21 597 PRINTS PR01042 Aspartyl-tRNA synthetase signature 481 497 1.1E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c06620 cae7573cb1621a45074cac079b37ab21 597 PRINTS PR01042 Aspartyl-tRNA synthetase signature 191 203 1.1E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c06620 cae7573cb1621a45074cac079b37ab21 597 Pfam PF02938 GAD domain 309 408 3.7E-29 T 12-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 MIM_c06620 cae7573cb1621a45074cac079b37ab21 597 SUPERFAMILY SSF55261 292 417 1.32E-43 T 12-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 MIM_c06620 cae7573cb1621a45074cac079b37ab21 597 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 590 8.7E-246 T 12-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 MIM_c06620 cae7573cb1621a45074cac079b37ab21 597 SUPERFAMILY SSF50249 1 105 2.86E-32 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c06620 cae7573cb1621a45074cac079b37ab21 597 Gene3D G3DSA:3.30.1360.30 273 427 1.5E-196 T 12-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 MIM_c06620 cae7573cb1621a45074cac079b37ab21 597 SUPERFAMILY SSF55681 111 592 4.79E-104 T 12-10-2018 MIM_c06620 cae7573cb1621a45074cac079b37ab21 597 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 1 591 33.65 T 12-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 MIM_c34510 2522eaed334657162e80298ebe25dd38 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 8.5E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c34510 2522eaed334657162e80298ebe25dd38 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 8.7E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c34510 2522eaed334657162e80298ebe25dd38 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 8.7E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c34510 2522eaed334657162e80298ebe25dd38 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 8.7E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c34510 2522eaed334657162e80298ebe25dd38 300 SUPERFAMILY SSF46785 2 83 2.82E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c34510 2522eaed334657162e80298ebe25dd38 300 Gene3D G3DSA:3.40.190.10 164 263 5.9E-55 T 12-10-2018 MIM_c34510 2522eaed334657162e80298ebe25dd38 300 SUPERFAMILY SSF53850 93 296 5.58E-40 T 12-10-2018 MIM_c34510 2522eaed334657162e80298ebe25dd38 300 Gene3D G3DSA:1.10.10.10 7 93 4.9E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c34510 2522eaed334657162e80298ebe25dd38 300 Gene3D G3DSA:3.40.190.10 104 289 5.9E-55 T 12-10-2018 MIM_c34510 2522eaed334657162e80298ebe25dd38 300 Pfam PF03466 LysR substrate binding domain 93 292 2.5E-41 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c22670 a3a47739e825c0059e0cb736c2aa968a 499 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 53 495 1.6E-147 T 12-10-2018 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021|GO:0055114 MIM_c22670 a3a47739e825c0059e0cb736c2aa968a 499 Pfam PF13746 4Fe-4S dicluster domain 231 337 1.1E-42 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MIM_c22670 a3a47739e825c0059e0cb736c2aa968a 499 Pfam PF12801 4Fe-4S binding domain 108 149 4.4E-11 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MIM_c22670 a3a47739e825c0059e0cb736c2aa968a 499 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 284 295 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MIM_c22670 a3a47739e825c0059e0cb736c2aa968a 499 Gene3D G3DSA:2.60.40.10 373 496 4.9E-17 T 12-10-2018 IPR013783 Immunoglobulin-like fold MIM_c22670 a3a47739e825c0059e0cb736c2aa968a 499 SUPERFAMILY SSF54862 117 337 3.77E-31 T 12-10-2018 MIM_c22670 a3a47739e825c0059e0cb736c2aa968a 499 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 372 497 2.3E-22 T 12-10-2018 IPR032879 FixG, C-terminal immunoglobulin-like domain MIM_c35630 ad8fa1e05e6c1fad157aa9bcaaa56dc5 320 Pfam PF09084 NMT1/THI5 like 44 250 1.5E-24 T 12-10-2018 IPR015168 SsuA/THI5-like MIM_c35630 ad8fa1e05e6c1fad157aa9bcaaa56dc5 320 Gene3D G3DSA:1.10.8.450 241 273 5.2E-53 T 12-10-2018 MIM_c35630 ad8fa1e05e6c1fad157aa9bcaaa56dc5 320 Gene3D G3DSA:3.40.190.10 112 209 5.2E-53 T 12-10-2018 MIM_c35630 ad8fa1e05e6c1fad157aa9bcaaa56dc5 320 Gene3D G3DSA:3.40.190.10 39 300 5.2E-53 T 12-10-2018 MIM_c35630 ad8fa1e05e6c1fad157aa9bcaaa56dc5 320 SUPERFAMILY SSF53850 31 306 2.72E-35 T 12-10-2018 MIM_c13100 28269e929c2318ac6a45b01e6c33919b 435 Pfam PF10093 Uncharacterized protein conserved in bacteria (DUF2331) 298 428 2.5E-36 T 12-10-2018 IPR016633 Uncharacterised conserved protein UCP015557 MIM_c13100 28269e929c2318ac6a45b01e6c33919b 435 Pfam PF10093 Uncharacterized protein conserved in bacteria (DUF2331) 9 232 2.3E-86 T 12-10-2018 IPR016633 Uncharacterised conserved protein UCP015557 MIM_c13100 28269e929c2318ac6a45b01e6c33919b 435 PIRSF PIRSF015557 4 245 3.0E-87 T 12-10-2018 IPR016633 Uncharacterised conserved protein UCP015557 MIM_c13100 28269e929c2318ac6a45b01e6c33919b 435 PIRSF PIRSF015557 284 433 3.0E-37 T 12-10-2018 IPR016633 Uncharacterised conserved protein UCP015557 MIM_c27580 4621abc05149fcb40e627daf25d29a2f 384 Gene3D G3DSA:3.30.9.20 40 248 4.3E-108 T 12-10-2018 MIM_c27580 4621abc05149fcb40e627daf25d29a2f 384 Gene3D G3DSA:3.50.50.60 3 333 4.3E-108 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c27580 4621abc05149fcb40e627daf25d29a2f 384 Pfam PF01494 FAD binding domain 128 294 2.4E-8 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 MIM_c27580 4621abc05149fcb40e627daf25d29a2f 384 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 274 290 5.0E-9 T 12-10-2018 MIM_c27580 4621abc05149fcb40e627daf25d29a2f 384 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 129 144 5.0E-9 T 12-10-2018 MIM_c27580 4621abc05149fcb40e627daf25d29a2f 384 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 5.0E-9 T 12-10-2018 MIM_c27580 4621abc05149fcb40e627daf25d29a2f 384 SUPERFAMILY SSF51905 1 333 1.17E-38 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c23980 bc77b40b28d3fc37c71119a10cc48eea 233 Gene3D G3DSA:3.30.950.10 120 233 8.1E-43 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 MIM_c23980 bc77b40b28d3fc37c71119a10cc48eea 233 SUPERFAMILY SSF53790 4 231 7.46E-57 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 MIM_c23980 bc77b40b28d3fc37c71119a10cc48eea 233 Gene3D G3DSA:3.40.1010.10 2 119 5.9E-34 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 MIM_c08620 572e7ea3081874e483866b81598ebe2c 117 Pfam PF01042 Endoribonuclease L-PSP 5 116 4.0E-19 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 MIM_c08620 572e7ea3081874e483866b81598ebe2c 117 Gene3D G3DSA:3.30.1330.40 1 117 1.3E-36 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MIM_c08620 572e7ea3081874e483866b81598ebe2c 117 SUPERFAMILY SSF55298 2 116 3.3E-27 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MIM_c27630 74c534a5e5c26ec4faacb370fea07e16 234 Gene3D G3DSA:1.10.357.10 60 198 9.3E-33 T 12-10-2018 MIM_c27630 74c534a5e5c26ec4faacb370fea07e16 234 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 61 6.5E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c27630 74c534a5e5c26ec4faacb370fea07e16 234 Gene3D G3DSA:1.10.10.60 14 59 2.4E-17 T 12-10-2018 MIM_c27630 74c534a5e5c26ec4faacb370fea07e16 234 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 6.0E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c27630 74c534a5e5c26ec4faacb370fea07e16 234 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 6.0E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c27630 74c534a5e5c26ec4faacb370fea07e16 234 SUPERFAMILY SSF46689 9 78 2.05E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c27630 74c534a5e5c26ec4faacb370fea07e16 234 SUPERFAMILY SSF48498 87 201 8.07E-22 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MIM_c09120 73f11d21e2256fc6da2252d0c9172d49 390 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 385 3.1E-12 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c09120 73f11d21e2256fc6da2252d0c9172d49 390 Gene3D G3DSA:1.10.3720.10 70 172 2.1E-15 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c09120 73f11d21e2256fc6da2252d0c9172d49 390 Gene3D G3DSA:1.10.3720.10 173 386 2.2E-34 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c09120 73f11d21e2256fc6da2252d0c9172d49 390 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 82 145 2.9E-16 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c09120 73f11d21e2256fc6da2252d0c9172d49 390 SUPERFAMILY SSF161098 181 371 4.71E-27 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c09120 73f11d21e2256fc6da2252d0c9172d49 390 SUPERFAMILY SSF161098 82 150 6.41E-14 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c28070 179b16635b5c11b9b706df2ef5f31fb3 287 Gene3D G3DSA:3.10.620.30 86 247 9.8E-78 T 12-10-2018 MIM_c28070 179b16635b5c11b9b706df2ef5f31fb3 287 Gene3D G3DSA:2.60.40.2250 9 255 9.8E-78 T 12-10-2018 MIM_c28070 179b16635b5c11b9b706df2ef5f31fb3 287 Pfam PF01841 Transglutaminase-like superfamily 139 225 2.9E-21 T 12-10-2018 IPR002931 Transglutaminase-like MIM_c28070 179b16635b5c11b9b706df2ef5f31fb3 287 SMART SM00460 166 227 3.8E-18 T 12-10-2018 IPR002931 Transglutaminase-like MIM_c28070 179b16635b5c11b9b706df2ef5f31fb3 287 SUPERFAMILY SSF54001 110 255 2.8E-32 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily MIM_c19060 1cd3b23bae7ad64ce4d0ec8c2fbc4c73 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 292 1.5E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c19060 1cd3b23bae7ad64ce4d0ec8c2fbc4c73 293 Gene3D G3DSA:1.10.3720.10 51 292 9.6E-61 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c19060 1cd3b23bae7ad64ce4d0ec8c2fbc4c73 293 SUPERFAMILY SSF161098 55 282 2.75E-52 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c16970 8bd324bba8dd692e179a101ed87ebdab 543 Gene3D G3DSA:1.10.40.30 398 483 1.6E-86 T 12-10-2018 MIM_c16970 8bd324bba8dd692e179a101ed87ebdab 543 PRINTS PR00145 Argininosuccinate lyase family signature 313 329 2.9E-16 T 12-10-2018 MIM_c16970 8bd324bba8dd692e179a101ed87ebdab 543 PRINTS PR00145 Argininosuccinate lyase family signature 229 245 2.9E-16 T 12-10-2018 MIM_c16970 8bd324bba8dd692e179a101ed87ebdab 543 PRINTS PR00145 Argininosuccinate lyase family signature 178 198 2.9E-16 T 12-10-2018 MIM_c16970 8bd324bba8dd692e179a101ed87ebdab 543 PRINTS PR00145 Argininosuccinate lyase family signature 269 293 2.9E-16 T 12-10-2018 MIM_c16970 8bd324bba8dd692e179a101ed87ebdab 543 PRINTS PR00145 Argininosuccinate lyase family signature 137 159 2.9E-16 T 12-10-2018 MIM_c16970 8bd324bba8dd692e179a101ed87ebdab 543 Gene3D G3DSA:1.20.200.10 143 495 1.6E-86 T 12-10-2018 MIM_c16970 8bd324bba8dd692e179a101ed87ebdab 543 PRINTS PR00149 Fumarate lyase superfamily signature 138 156 7.1E-6 T 12-10-2018 IPR000362 Fumarate lyase family MIM_c16970 8bd324bba8dd692e179a101ed87ebdab 543 PRINTS PR00149 Fumarate lyase superfamily signature 313 329 7.1E-6 T 12-10-2018 IPR000362 Fumarate lyase family MIM_c16970 8bd324bba8dd692e179a101ed87ebdab 543 PRINTS PR00149 Fumarate lyase superfamily signature 183 201 7.1E-6 T 12-10-2018 IPR000362 Fumarate lyase family MIM_c16970 8bd324bba8dd692e179a101ed87ebdab 543 SUPERFAMILY SSF48557 66 506 7.7E-70 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 MIM_c16970 8bd324bba8dd692e179a101ed87ebdab 543 Pfam PF00206 Lyase 136 338 2.3E-25 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal MIM_c16970 8bd324bba8dd692e179a101ed87ebdab 543 Pfam PF14698 Argininosuccinate lyase C-terminal 400 481 5.5E-8 T 12-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MIM_c05210 4206d25cbe35fe6c627ddb0623545148 280 SUPERFAMILY SSF51730 8 279 2.75E-94 T 12-10-2018 IPR029041 FAD-linked oxidoreductase-like MIM_c05210 4206d25cbe35fe6c627ddb0623545148 280 Gene3D G3DSA:3.20.20.220 2 280 1.8E-98 T 12-10-2018 MIM_c05210 4206d25cbe35fe6c627ddb0623545148 280 Pfam PF02219 Methylenetetrahydrofolate reductase 7 278 3.5E-90 T 12-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 MIM_c05210 4206d25cbe35fe6c627ddb0623545148 280 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 9 278 1.5E-98 T 12-10-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 MIM_c29050 eb0d52000513f09bba17817c6da0541f 48 SUPERFAMILY SSF57840 1 41 5.76E-15 T 12-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c29050 eb0d52000513f09bba17817c6da0541f 48 Pfam PF00444 Ribosomal protein L36 1 41 7.1E-19 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c29050 eb0d52000513f09bba17817c6da0541f 48 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 41 18.355 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c29050 eb0d52000513f09bba17817c6da0541f 48 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 17 41 7.0E-4 T 12-10-2018 MIM_c29050 eb0d52000513f09bba17817c6da0541f 48 ProSitePatterns PS00828 Ribosomal protein L36 signature. 14 40 - T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c29050 eb0d52000513f09bba17817c6da0541f 48 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 41 6.2E-10 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c36890 beb4217954ba50e1f4e3576c66a4c863 541 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 395 414 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MIM_c36890 beb4217954ba50e1f4e3576c66a4c863 541 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 282 435 2.0E-30 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MIM_c36890 beb4217954ba50e1f4e3576c66a4c863 541 SUPERFAMILY SSF47203 287 439 1.27E-39 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c36890 beb4217954ba50e1f4e3576c66a4c863 541 SUPERFAMILY SSF56645 80 291 3.95E-29 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c36890 beb4217954ba50e1f4e3576c66a4c863 541 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 176 272 1.5E-15 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MIM_c36890 beb4217954ba50e1f4e3576c66a4c863 541 Gene3D G3DSA:2.40.110.20 127 277 1.6E-49 T 12-10-2018 MIM_c36890 beb4217954ba50e1f4e3576c66a4c863 541 Gene3D G3DSA:1.20.140.10 278 447 3.1E-37 T 12-10-2018 MIM_c05510 a10e11cc6b1e77537a6f411364919990 288 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 2 287 38.123 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 MIM_c05510 a10e11cc6b1e77537a6f411364919990 288 PIRSF PIRSF005052 2 287 1.4E-105 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 MIM_c05510 a10e11cc6b1e77537a6f411364919990 288 Gene3D G3DSA:3.40.50.300 1 168 2.1E-6 T 12-10-2018 MIM_c05510 a10e11cc6b1e77537a6f411364919990 288 Pfam PF03668 P-loop ATPase protein family 3 283 2.9E-86 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 MIM_c05510 a10e11cc6b1e77537a6f411364919990 288 SUPERFAMILY SSF52540 4 164 3.87E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c30470 0f62934352cc75249cb7d09fa55eb567 249 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c30470 0f62934352cc75249cb7d09fa55eb567 249 Gene3D G3DSA:3.40.50.300 6 249 5.2E-78 T 12-10-2018 MIM_c30470 0f62934352cc75249cb7d09fa55eb567 249 PIRSF PIRSF039085 5 249 2.0E-101 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MIM_c30470 0f62934352cc75249cb7d09fa55eb567 249 SUPERFAMILY SSF52540 8 243 1.05E-78 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c30470 0f62934352cc75249cb7d09fa55eb567 249 SMART SM00382 33 221 9.6E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c30470 0f62934352cc75249cb7d09fa55eb567 249 Pfam PF00005 ABC transporter 24 173 6.1E-37 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c27210 c706455b26a2d7a187f1589353f63095 524 SUPERFAMILY SSF56801 8 520 2.35E-144 T 12-10-2018 MIM_c27210 c706455b26a2d7a187f1589353f63095 524 Gene3D G3DSA:1.10.10.2900 244 314 4.4E-28 T 12-10-2018 MIM_c27210 c706455b26a2d7a187f1589353f63095 524 Gene3D G3DSA:3.30.300.310 422 523 3.9E-28 T 12-10-2018 MIM_c27210 c706455b26a2d7a187f1589353f63095 524 TIGRFAM TIGR02262 benz_CoA_lig: benzoate-CoA ligase family 9 517 1.4E-232 T 12-10-2018 IPR011957 Benzoate-CoA ligase family GO:0005524|GO:0016405 MIM_c27210 c706455b26a2d7a187f1589353f63095 524 Gene3D G3DSA:3.40.50.980 4 243 1.2E-74 T 12-10-2018 MIM_c27210 c706455b26a2d7a187f1589353f63095 524 Pfam PF13193 AMP-binding enzyme C-terminal domain 430 509 2.2E-19 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MIM_c27210 c706455b26a2d7a187f1589353f63095 524 Gene3D G3DSA:2.30.38.10 315 421 1.7E-37 T 12-10-2018 MIM_c27210 c706455b26a2d7a187f1589353f63095 524 Pfam PF00501 AMP-binding enzyme 21 422 8.0E-92 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MIM_c30020 81343f9206b725e6e3422ce639eb2435 462 PRINTS PR00762 Chloride channel signature 377 393 4.4E-22 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MIM_c30020 81343f9206b725e6e3422ce639eb2435 462 PRINTS PR00762 Chloride channel signature 88 105 4.4E-22 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MIM_c30020 81343f9206b725e6e3422ce639eb2435 462 PRINTS PR00762 Chloride channel signature 179 198 4.4E-22 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MIM_c30020 81343f9206b725e6e3422ce639eb2435 462 PRINTS PR00762 Chloride channel signature 347 367 4.4E-22 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MIM_c30020 81343f9206b725e6e3422ce639eb2435 462 PRINTS PR00762 Chloride channel signature 395 414 4.4E-22 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MIM_c30020 81343f9206b725e6e3422ce639eb2435 462 SUPERFAMILY SSF81340 7 440 1.31E-85 T 12-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 MIM_c30020 81343f9206b725e6e3422ce639eb2435 462 Pfam PF00654 Voltage gated chloride channel 76 427 1.9E-72 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MIM_c30020 81343f9206b725e6e3422ce639eb2435 462 Gene3D G3DSA:1.10.3080.10 23 444 2.1E-77 T 12-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 MIM_c30880 6e59037f2d547bc6e348fa139fe1c7bb 372 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 14 128 5.8E-33 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain MIM_c30880 6e59037f2d547bc6e348fa139fe1c7bb 372 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 194 225 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 MIM_c30880 6e59037f2d547bc6e348fa139fe1c7bb 372 Gene3D G3DSA:3.30.390.10 31 367 1.7E-121 T 12-10-2018 IPR029017 Enolase-like, N-terminal MIM_c30880 6e59037f2d547bc6e348fa139fe1c7bb 372 Pfam PF13378 Enolase C-terminal domain-like 151 364 2.0E-48 T 12-10-2018 IPR029065 Enolase C-terminal domain-like MIM_c30880 6e59037f2d547bc6e348fa139fe1c7bb 372 TIGRFAM TIGR02534 mucon_cyclo: muconate and chloromuconate cycloisomerases 5 372 8.1E-165 T 12-10-2018 IPR013370 Muconate/chloromuconate cycloisomerase GO:0018849|GO:0018850|GO:0030145 MIM_c30880 6e59037f2d547bc6e348fa139fe1c7bb 372 SUPERFAMILY SSF54826 4 129 7.78E-33 T 12-10-2018 MIM_c30880 6e59037f2d547bc6e348fa139fe1c7bb 372 Gene3D G3DSA:3.20.20.120 121 356 1.7E-121 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MIM_c30880 6e59037f2d547bc6e348fa139fe1c7bb 372 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 103 128 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 MIM_c30880 6e59037f2d547bc6e348fa139fe1c7bb 372 SUPERFAMILY SSF51604 132 371 1.44E-61 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MIM_c30880 6e59037f2d547bc6e348fa139fe1c7bb 372 SMART SM00922 146 244 3.0E-18 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MIM_c15940 2609f7a07aa1086054fd8c23cbadf7d4 148 SUPERFAMILY SSF51283 14 146 1.7E-49 T 12-10-2018 IPR036157 dUTPase-like superfamily MIM_c15940 2609f7a07aa1086054fd8c23cbadf7d4 148 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 5 147 32.317 T 12-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 MIM_c15940 2609f7a07aa1086054fd8c23cbadf7d4 148 Gene3D G3DSA:2.70.40.10 1 147 1.9E-51 T 12-10-2018 IPR036157 dUTPase-like superfamily MIM_c15940 2609f7a07aa1086054fd8c23cbadf7d4 148 TIGRFAM TIGR00576 dut: dUTP diphosphatase 8 147 2.5E-47 T 12-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 MIM_c15940 2609f7a07aa1086054fd8c23cbadf7d4 148 Pfam PF00692 dUTPase 15 146 1.7E-36 T 12-10-2018 IPR029054 dUTPase-like MIM_c02630 04e573b0b00822d8904b5cceaac96db1 341 Gene3D G3DSA:3.60.21.10 41 280 3.4E-20 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like MIM_c02630 04e573b0b00822d8904b5cceaac96db1 341 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 44 259 1.4E-13 T 12-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 MIM_c02630 04e573b0b00822d8904b5cceaac96db1 341 SUPERFAMILY SSF56300 41 280 3.48E-35 T 12-10-2018 MIM_c07710 55194351d8eef9c82300f914eee219d8 401 Gene3D G3DSA:2.30.30.40 330 399 6.0E-13 T 12-10-2018 MIM_c07710 55194351d8eef9c82300f914eee219d8 401 Pfam PF08239 Bacterial SH3 domain 343 396 4.3E-9 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type MIM_c36140 582c49f518249313048a21692241ab78 269 Pfam PF00290 Tryptophan synthase alpha chain 8 263 7.2E-100 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MIM_c36140 582c49f518249313048a21692241ab78 269 SUPERFAMILY SSF51366 1 247 5.18E-91 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MIM_c36140 582c49f518249313048a21692241ab78 269 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 257 4.4E-79 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MIM_c36140 582c49f518249313048a21692241ab78 269 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 263 36.434 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MIM_c36140 582c49f518249313048a21692241ab78 269 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 12-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MIM_c36140 582c49f518249313048a21692241ab78 269 Gene3D G3DSA:3.20.20.70 1 269 5.5E-102 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c17670 fd95e3fc4dbf7deffe98f91080d33441 331 PRINTS PR00410 Phenol hydroxylase reductase family signature 210 229 7.8E-23 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MIM_c17670 fd95e3fc4dbf7deffe98f91080d33441 331 PRINTS PR00410 Phenol hydroxylase reductase family signature 298 306 7.8E-23 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MIM_c17670 fd95e3fc4dbf7deffe98f91080d33441 331 PRINTS PR00410 Phenol hydroxylase reductase family signature 136 148 7.8E-23 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MIM_c17670 fd95e3fc4dbf7deffe98f91080d33441 331 PRINTS PR00410 Phenol hydroxylase reductase family signature 195 204 7.8E-23 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MIM_c17670 fd95e3fc4dbf7deffe98f91080d33441 331 PRINTS PR00410 Phenol hydroxylase reductase family signature 153 160 7.8E-23 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MIM_c17670 fd95e3fc4dbf7deffe98f91080d33441 331 SUPERFAMILY SSF52343 189 328 7.46E-31 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MIM_c17670 fd95e3fc4dbf7deffe98f91080d33441 331 SUPERFAMILY SSF54292 2 96 1.84E-21 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MIM_c17670 fd95e3fc4dbf7deffe98f91080d33441 331 Pfam PF00970 Oxidoreductase FAD-binding domain 114 200 2.1E-12 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 MIM_c17670 fd95e3fc4dbf7deffe98f91080d33441 331 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 12 86 1.2E-10 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MIM_c17670 fd95e3fc4dbf7deffe98f91080d33441 331 Gene3D G3DSA:3.40.50.80 200 330 2.0E-29 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MIM_c17670 fd95e3fc4dbf7deffe98f91080d33441 331 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 42 50 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MIM_c17670 fd95e3fc4dbf7deffe98f91080d33441 331 Gene3D G3DSA:3.10.20.30 4 101 6.8E-21 T 12-10-2018 IPR012675 Beta-grasp domain superfamily MIM_c17670 fd95e3fc4dbf7deffe98f91080d33441 331 Gene3D G3DSA:2.40.30.10 105 199 8.3E-24 T 12-10-2018 MIM_c17670 fd95e3fc4dbf7deffe98f91080d33441 331 Pfam PF00175 Oxidoreductase NAD-binding domain 211 310 7.8E-14 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MIM_c17670 fd95e3fc4dbf7deffe98f91080d33441 331 SUPERFAMILY SSF63380 78 205 2.07E-23 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MIM_c40110 2269d4edd88ae257414390fd069aeb63 787 SUPERFAMILY SSF47384 547 621 1.02E-7 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MIM_c40110 2269d4edd88ae257414390fd069aeb63 787 SMART SM00387 666 778 2.7E-31 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c40110 2269d4edd88ae257414390fd069aeb63 787 PIRSF PIRSF037347 3 781 4.9E-213 T 12-10-2018 IPR017181 Signal transduction histidine kinase, CHASE2 sensor domain-containing, predicted MIM_c40110 2269d4edd88ae257414390fd069aeb63 787 SUPERFAMILY SSF55874 612 776 2.62E-40 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c40110 2269d4edd88ae257414390fd069aeb63 787 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 666 777 9.1E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c40110 2269d4edd88ae257414390fd069aeb63 787 SMART SM01080 33 307 6.3E-70 T 12-10-2018 IPR007890 CHASE2 MIM_c40110 2269d4edd88ae257414390fd069aeb63 787 Gene3D G3DSA:3.30.565.10 625 785 2.9E-37 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c40110 2269d4edd88ae257414390fd069aeb63 787 Pfam PF05226 CHASE2 domain 20 306 5.3E-51 T 12-10-2018 IPR007890 CHASE2 MIM_c40110 2269d4edd88ae257414390fd069aeb63 787 Gene3D G3DSA:1.10.287.130 545 620 4.3E-7 T 12-10-2018 MIM_c40110 2269d4edd88ae257414390fd069aeb63 787 PRINTS PR00344 Bacterial sensor protein C-terminal signature 703 717 3.9E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c40110 2269d4edd88ae257414390fd069aeb63 787 PRINTS PR00344 Bacterial sensor protein C-terminal signature 738 756 3.9E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c40110 2269d4edd88ae257414390fd069aeb63 787 PRINTS PR00344 Bacterial sensor protein C-terminal signature 762 775 3.9E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c00960 57a3e749a20ff08167c51adb5766fbf6 337 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 89 1.0E-5 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MIM_c00960 57a3e749a20ff08167c51adb5766fbf6 337 SUPERFAMILY SSF50129 9 142 1.89E-27 T 12-10-2018 IPR011032 GroES-like superfamily MIM_c00960 57a3e749a20ff08167c51adb5766fbf6 337 Pfam PF13602 Zinc-binding dehydrogenase 194 334 2.0E-18 T 12-10-2018 MIM_c00960 57a3e749a20ff08167c51adb5766fbf6 337 SMART SM00829 14 334 1.0E-9 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MIM_c00960 57a3e749a20ff08167c51adb5766fbf6 337 Gene3D G3DSA:3.90.180.10 25 334 2.1E-105 T 12-10-2018 MIM_c00960 57a3e749a20ff08167c51adb5766fbf6 337 TIGRFAM TIGR02817 adh_fam_1: zinc-binding alcohol dehydrogenase family protein 2 337 3.6E-166 T 12-10-2018 IPR014182 Alcohol dehydrogenase, zinc-binding type 1 GO:0008270 MIM_c00960 57a3e749a20ff08167c51adb5766fbf6 337 SUPERFAMILY SSF51735 117 283 6.32E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c00960 57a3e749a20ff08167c51adb5766fbf6 337 Gene3D G3DSA:3.40.50.720 128 273 2.1E-105 T 12-10-2018 MIM_c20810 6b94f2c762f360ef0045ae88b665408e 186 Gene3D G3DSA:1.20.1290.10 43 165 9.7E-18 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c20810 6b94f2c762f360ef0045ae88b665408e 186 SUPERFAMILY SSF69118 9 155 4.32E-24 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c37160 0b10163b22e9ad5a98092b932a185df5 261 Gene3D G3DSA:1.10.10.10 9 87 8.1E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c37160 0b10163b22e9ad5a98092b932a185df5 261 SUPERFAMILY SSF64288 68 241 4.08E-29 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MIM_c37160 0b10163b22e9ad5a98092b932a185df5 261 Gene3D G3DSA:3.40.1410.10 88 244 2.0E-27 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MIM_c37160 0b10163b22e9ad5a98092b932a185df5 261 SUPERFAMILY SSF46785 14 83 1.36E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c37160 0b10163b22e9ad5a98092b932a185df5 261 SMART SM00866 102 238 3.7E-17 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MIM_c37160 0b10163b22e9ad5a98092b932a185df5 261 Pfam PF07702 UTRA domain 107 237 3.1E-22 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MIM_c37160 0b10163b22e9ad5a98092b932a185df5 261 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 1.3E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c37160 0b10163b22e9ad5a98092b932a185df5 261 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 1.3E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c37160 0b10163b22e9ad5a98092b932a185df5 261 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 80 2.8E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c37160 0b10163b22e9ad5a98092b932a185df5 261 SMART SM00345 21 80 1.6E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c22130 0254045aee735708bf0fafba1c313c68 102 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 101 5.9E-45 T 12-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c22130 0254045aee735708bf0fafba1c313c68 102 SUPERFAMILY SSF51278 1 101 5.76E-47 T 12-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c22130 0254045aee735708bf0fafba1c313c68 102 Pfam PF00699 Urease beta subunit 3 99 1.4E-44 T 12-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c22130 0254045aee735708bf0fafba1c313c68 102 Gene3D G3DSA:2.10.150.10 1 102 2.6E-46 T 12-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c22130 0254045aee735708bf0fafba1c313c68 102 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 31.526 T 12-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MIM_c37990 539fa1ee05e1c30eb1c63a565d664852 179 Gene3D G3DSA:1.25.40.10 79 179 3.7E-27 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MIM_c37990 539fa1ee05e1c30eb1c63a565d664852 179 SUPERFAMILY SSF48452 2 175 2.81E-62 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MIM_c37990 539fa1ee05e1c30eb1c63a565d664852 179 Pfam PF06041 Bacterial protein of unknown function (DUF924) 6 176 2.8E-57 T 12-10-2018 IPR010323 Protein of unknown function DUF924 MIM_c37990 539fa1ee05e1c30eb1c63a565d664852 179 Gene3D G3DSA:1.20.58.320 1 78 5.4E-28 T 12-10-2018 MIM_c11110 20e410ab295322fd95afd4442cfd2212 570 Gene3D G3DSA:2.140.10.10 35 570 8.0E-185 T 12-10-2018 MIM_c11110 20e410ab295322fd95afd4442cfd2212 570 TIGRFAM TIGR03075 PQQ_enz_alc_DH: PQQ-dependent dehydrogenase, methanol/ethanol family 35 541 5.6E-185 T 12-10-2018 IPR017512 PQQ-dependent dehydrogenase, methanol/ethanol family GO:0005509|GO:0016020|GO:0016614|GO:0055114 MIM_c11110 20e410ab295322fd95afd4442cfd2212 570 SMART SM00564 434 471 39.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c11110 20e410ab295322fd95afd4442cfd2212 570 SMART SM00564 144 175 1.9E-4 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c11110 20e410ab295322fd95afd4442cfd2212 570 SMART SM00564 189 226 0.032 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c11110 20e410ab295322fd95afd4442cfd2212 570 SMART SM00564 277 304 58.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c11110 20e410ab295322fd95afd4442cfd2212 570 SMART SM00564 480 512 1.6E-7 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c11110 20e410ab295322fd95afd4442cfd2212 570 SMART SM00564 93 124 18.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c11110 20e410ab295322fd95afd4442cfd2212 570 SUPERFAMILY SSF50998 43 558 9.81E-160 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MIM_c11110 20e410ab295322fd95afd4442cfd2212 570 Pfam PF13360 PQQ-like domain 81 224 8.8E-19 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat MIM_c11110 20e410ab295322fd95afd4442cfd2212 570 Pfam PF13360 PQQ-like domain 454 513 4.7E-10 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat MIM_c33040 2ea32c8c0caf74abdb952d2e7c0d86fd 368 SUPERFAMILY SSF51395 1 350 7.09E-106 T 12-10-2018 MIM_c33040 2ea32c8c0caf74abdb952d2e7c0d86fd 368 Gene3D G3DSA:3.20.20.70 1 364 9.0E-120 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c33040 2ea32c8c0caf74abdb952d2e7c0d86fd 368 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 3 343 9.0E-65 T 12-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 MIM_c31710 5a6da78fd44ea8b4895312da52eddd7d 291 Pfam PF03466 LysR substrate binding domain 90 289 8.8E-36 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c31710 5a6da78fd44ea8b4895312da52eddd7d 291 Gene3D G3DSA:1.10.10.10 4 89 1.7E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c31710 5a6da78fd44ea8b4895312da52eddd7d 291 SUPERFAMILY SSF53850 90 290 3.72E-38 T 12-10-2018 MIM_c31710 5a6da78fd44ea8b4895312da52eddd7d 291 Gene3D G3DSA:3.40.190.290 92 288 3.3E-58 T 12-10-2018 MIM_c31710 5a6da78fd44ea8b4895312da52eddd7d 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 4.2E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c31710 5a6da78fd44ea8b4895312da52eddd7d 291 SUPERFAMILY SSF46785 5 113 1.91E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c02340 7c6702a7561007657c511d23c583f3e8 596 Pfam PF13360 PQQ-like domain 76 229 8.1E-16 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat MIM_c02340 7c6702a7561007657c511d23c583f3e8 596 Pfam PF13360 PQQ-like domain 473 540 3.1E-8 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat MIM_c02340 7c6702a7561007657c511d23c583f3e8 596 SUPERFAMILY SSF50998 39 564 1.57E-123 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MIM_c02340 7c6702a7561007657c511d23c583f3e8 596 SMART SM00564 186 226 9.6E-4 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c02340 7c6702a7561007657c511d23c583f3e8 596 SMART SM00564 329 376 560.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c02340 7c6702a7561007657c511d23c583f3e8 596 SMART SM00564 279 306 12.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c02340 7c6702a7561007657c511d23c583f3e8 596 SMART SM00564 499 531 0.12 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c02340 7c6702a7561007657c511d23c583f3e8 596 SMART SM00564 87 119 0.002 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c02340 7c6702a7561007657c511d23c583f3e8 596 SMART SM00564 456 490 9.9 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c02340 7c6702a7561007657c511d23c583f3e8 596 SMART SM00564 141 172 0.014 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c02340 7c6702a7561007657c511d23c583f3e8 596 Gene3D G3DSA:2.140.10.10 16 590 2.7E-168 T 12-10-2018 MIM_c40570 ae8aef27f373bfb6935e46036bb4c5b0 461 SUPERFAMILY SSF75304 5 457 2.75E-113 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MIM_c40570 ae8aef27f373bfb6935e46036bb4c5b0 461 ProSitePatterns PS00571 Amidases signature. 155 186 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 MIM_c40570 ae8aef27f373bfb6935e46036bb4c5b0 461 Pfam PF01425 Amidase 26 440 4.3E-89 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MIM_c40570 ae8aef27f373bfb6935e46036bb4c5b0 461 Gene3D G3DSA:3.90.1300.10 9 450 1.5E-118 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MIM_c17810 7368f062f9229cf8ddfdb45feeb3abaa 205 Gene3D G3DSA:3.40.50.300 2 205 2.6E-30 T 12-10-2018 MIM_c17810 7368f062f9229cf8ddfdb45feeb3abaa 205 Pfam PF06414 Zeta toxin 3 144 7.3E-10 T 12-10-2018 IPR010488 Zeta toxin domain GO:0005524|GO:0016301 MIM_c17810 7368f062f9229cf8ddfdb45feeb3abaa 205 SUPERFAMILY SSF52540 1 138 1.35E-10 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c25910 73bda4f0cd8604688284a6081d5115eb 258 SMART SM00382 36 246 1.4E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c25910 73bda4f0cd8604688284a6081d5115eb 258 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c25910 73bda4f0cd8604688284a6081d5115eb 258 Gene3D G3DSA:3.40.50.300 10 256 4.1E-66 T 12-10-2018 MIM_c25910 73bda4f0cd8604688284a6081d5115eb 258 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 12 258 7.8E-121 T 12-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 MIM_c25910 73bda4f0cd8604688284a6081d5115eb 258 Pfam PF00005 ABC transporter 28 182 6.1E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c25910 73bda4f0cd8604688284a6081d5115eb 258 SUPERFAMILY SSF52540 11 244 2.26E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c30520 8ba7ce9aa3c1059af5b5bc7bcf0e1e5a 457 Pfam PF07690 Major Facilitator Superfamily 34 410 2.8E-56 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c30520 8ba7ce9aa3c1059af5b5bc7bcf0e1e5a 457 Gene3D G3DSA:1.20.1250.20 20 457 8.9E-98 T 12-10-2018 MIM_c30520 8ba7ce9aa3c1059af5b5bc7bcf0e1e5a 457 ProSitePatterns PS00216 Sugar transport proteins signature 1. 81 97 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MIM_c30520 8ba7ce9aa3c1059af5b5bc7bcf0e1e5a 457 ProSitePatterns PS00217 Sugar transport proteins signature 2. 123 148 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MIM_c30520 8ba7ce9aa3c1059af5b5bc7bcf0e1e5a 457 SUPERFAMILY SSF103473 12 455 3.92E-95 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c27350 03e6e67b33ba5b10679f198045fcc4e9 305 SUPERFAMILY SSF53850 90 289 1.48E-29 T 12-10-2018 MIM_c27350 03e6e67b33ba5b10679f198045fcc4e9 305 SUPERFAMILY SSF46785 2 111 9.28E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c27350 03e6e67b33ba5b10679f198045fcc4e9 305 Gene3D G3DSA:1.10.10.10 3 87 3.0E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c27350 03e6e67b33ba5b10679f198045fcc4e9 305 Gene3D G3DSA:3.40.190.290 92 287 1.2E-31 T 12-10-2018 MIM_c27350 03e6e67b33ba5b10679f198045fcc4e9 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 64 6.9E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c27350 03e6e67b33ba5b10679f198045fcc4e9 305 Pfam PF03466 LysR substrate binding domain 89 275 3.4E-23 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c30080 ed5e5305a383fbd8dd911909aa34770f 255 SUPERFAMILY SSF52540 2 232 1.03E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c30080 ed5e5305a383fbd8dd911909aa34770f 255 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c30080 ed5e5305a383fbd8dd911909aa34770f 255 Gene3D G3DSA:3.40.50.300 1 253 3.8E-63 T 12-10-2018 MIM_c30080 ed5e5305a383fbd8dd911909aa34770f 255 SMART SM00382 26 214 2.1E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c30080 ed5e5305a383fbd8dd911909aa34770f 255 Pfam PF00005 ABC transporter 17 165 3.8E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c13030 5cbab1a594ac174c04a3aef393302a7b 297 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 5 18 - T 12-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 MIM_c13030 5cbab1a594ac174c04a3aef393302a7b 297 Gene3D G3DSA:3.40.50.720 1 163 2.2E-59 T 12-10-2018 MIM_c13030 5cbab1a594ac174c04a3aef393302a7b 297 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 5 290 2.5E-130 T 12-10-2018 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|Reactome: R-HSA-70895 MIM_c13030 5cbab1a594ac174c04a3aef393302a7b 297 SUPERFAMILY SSF51735 1 163 1.71E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c13030 5cbab1a594ac174c04a3aef393302a7b 297 PIRSF PIRSF000103 1 297 2.5E-81 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 MIM_c13030 5cbab1a594ac174c04a3aef393302a7b 297 SUPERFAMILY SSF48179 164 294 1.59E-39 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c13030 5cbab1a594ac174c04a3aef393302a7b 297 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 290 1.8E-36 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MIM_c13030 5cbab1a594ac174c04a3aef393302a7b 297 Gene3D G3DSA:1.10.1040.10 165 296 7.3E-47 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MIM_c13030 5cbab1a594ac174c04a3aef393302a7b 297 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 162 4.0E-54 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 MIM_c40940 d4715fc5cf9726fc394ee54421357970 468 SUPERFAMILY SSF52540 74 385 4.78E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c40940 d4715fc5cf9726fc394ee54421357970 468 Gene3D G3DSA:1.20.120.430 127 468 1.1E-100 T 12-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 MIM_c40940 d4715fc5cf9726fc394ee54421357970 468 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 7 468 32.232 T 12-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 MIM_c40940 d4715fc5cf9726fc394ee54421357970 468 Gene3D G3DSA:3.40.50.300 222 395 1.1E-100 T 12-10-2018 MIM_c40940 d4715fc5cf9726fc394ee54421357970 468 Gene3D G3DSA:3.30.1360.120 1 126 3.5E-42 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 MIM_c40940 d4715fc5cf9726fc394ee54421357970 468 Pfam PF01926 50S ribosome-binding GTPase 224 337 2.2E-22 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 MIM_c40940 d4715fc5cf9726fc394ee54421357970 468 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 13 468 3.8E-105 T 12-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 MIM_c40940 d4715fc5cf9726fc394ee54421357970 468 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 223 346 2.0E-21 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MIM_c40940 d4715fc5cf9726fc394ee54421357970 468 Pfam PF10396 GTP-binding protein TrmE N-terminus 8 125 1.7E-37 T 12-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 MIM_c40940 d4715fc5cf9726fc394ee54421357970 468 Pfam PF12631 MnmE helical domain 128 465 2.1E-56 T 12-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 MIM_c40940 d4715fc5cf9726fc394ee54421357970 468 SUPERFAMILY SSF116878 126 468 9.15E-49 T 12-10-2018 MIM_c14000 4fd2473a613d648e9541f5def6a198ca 487 Pfam PF00171 Aldehyde dehydrogenase family 34 483 7.7E-133 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c14000 4fd2473a613d648e9541f5def6a198ca 487 Gene3D G3DSA:3.40.309.10 266 455 2.0E-138 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MIM_c14000 4fd2473a613d648e9541f5def6a198ca 487 SUPERFAMILY SSF53720 17 487 6.28E-135 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c14000 4fd2473a613d648e9541f5def6a198ca 487 Gene3D G3DSA:3.40.605.10 45 473 2.0E-138 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c29730 dd0702bd99567cfe13e829fe80bc5b3e 355 PIRSF PIRSF000294 18 348 8.2E-109 T 12-10-2018 IPR026259 Di-c-type haem protein, MauG/cytochrome c peroxidase GO:0016491|GO:0020037|GO:0055114 MIM_c29730 dd0702bd99567cfe13e829fe80bc5b3e 355 SUPERFAMILY SSF46626 52 203 1.65E-44 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c29730 dd0702bd99567cfe13e829fe80bc5b3e 355 Pfam PF03150 Di-haem cytochrome c peroxidase 68 215 2.6E-42 T 12-10-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 MIM_c29730 dd0702bd99567cfe13e829fe80bc5b3e 355 Gene3D G3DSA:1.10.760.10 64 201 4.7E-84 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c29730 dd0702bd99567cfe13e829fe80bc5b3e 355 Gene3D G3DSA:1.10.760.10 202 340 4.7E-84 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c29730 dd0702bd99567cfe13e829fe80bc5b3e 355 SUPERFAMILY SSF46626 192 339 2.01E-30 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c29730 dd0702bd99567cfe13e829fe80bc5b3e 355 Pfam PF00034 Cytochrome c 224 338 1.5E-5 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c30840 f018fe48c2feb682947e8aec78a695de 269 SMART SM00382 28 225 1.8E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c30840 f018fe48c2feb682947e8aec78a695de 269 Gene3D G3DSA:3.40.50.300 4 255 2.7E-65 T 12-10-2018 MIM_c30840 f018fe48c2feb682947e8aec78a695de 269 SUPERFAMILY SSF52540 4 231 1.41E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c30840 f018fe48c2feb682947e8aec78a695de 269 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c30840 f018fe48c2feb682947e8aec78a695de 269 Pfam PF00005 ABC transporter 20 167 1.5E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c05640 dc469cd39cefa3a907d4ce9e2ba6ae2a 250 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 2 246 44.694 T 12-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 MIM_c05640 dc469cd39cefa3a907d4ce9e2ba6ae2a 250 Pfam PF03746 LamB/YcsF family 4 241 1.2E-98 T 12-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 MIM_c05640 dc469cd39cefa3a907d4ce9e2ba6ae2a 250 Gene3D G3DSA:3.20.20.370 2 250 4.0E-99 T 12-10-2018 MIM_c05640 dc469cd39cefa3a907d4ce9e2ba6ae2a 250 SUPERFAMILY SSF88713 3 248 2.52E-95 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MIM_c24840 6df343c68cdac861e11335c6269c38c7 479 Gene3D G3DSA:3.40.309.10 249 437 2.2E-157 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MIM_c24840 6df343c68cdac861e11335c6269c38c7 479 Gene3D G3DSA:3.40.605.10 9 463 2.2E-157 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c24840 6df343c68cdac861e11335c6269c38c7 479 Pfam PF00171 Aldehyde dehydrogenase family 16 464 2.7E-147 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c24840 6df343c68cdac861e11335c6269c38c7 479 SUPERFAMILY SSF53720 3 465 7.59E-147 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c24840 6df343c68cdac861e11335c6269c38c7 479 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 244 251 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MIM_c14220 5ad3f31e9ad68b0d6d99b6fc7452d61d 331 Gene3D G3DSA:3.60.130.10 5 301 3.0E-86 T 12-10-2018 MIM_c14220 5ad3f31e9ad68b0d6d99b6fc7452d61d 331 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 18 282 1.2E-52 T 12-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 MIM_c14220 5ad3f31e9ad68b0d6d99b6fc7452d61d 331 SUPERFAMILY SSF51197 15 297 8.7E-81 T 12-10-2018 MIM_c16520 e43039bf8c7d7e5d9a910684d941db02 309 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 253 279 - T 12-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 MIM_c16520 e43039bf8c7d7e5d9a910684d941db02 309 SMART SM00893 3 182 2.4E-54 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MIM_c16520 e43039bf8c7d7e5d9a910684d941db02 309 PIRSF PIRSF000089 1 309 4.4E-105 T 12-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 MIM_c16520 e43039bf8c7d7e5d9a910684d941db02 309 SUPERFAMILY SSF52467 189 308 2.89E-47 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MIM_c16520 e43039bf8c7d7e5d9a910684d941db02 309 Pfam PF01012 Electron transfer flavoprotein domain 3 170 1.9E-38 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MIM_c16520 e43039bf8c7d7e5d9a910684d941db02 309 Gene3D G3DSA:3.40.50.620 3 183 7.9E-54 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c16520 e43039bf8c7d7e5d9a910684d941db02 309 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 190 272 8.0E-37 T 12-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 MIM_c16520 e43039bf8c7d7e5d9a910684d941db02 309 SUPERFAMILY SSF52402 3 185 2.23E-56 T 12-10-2018 MIM_c16520 e43039bf8c7d7e5d9a910684d941db02 309 Gene3D G3DSA:3.40.50.1220 184 309 1.6E-57 T 12-10-2018 MIM_c25210 d30337a8a2871f2e06137056aea02fb8 98 Pfam PF01381 Helix-turn-helix 20 60 1.2E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c25210 d30337a8a2871f2e06137056aea02fb8 98 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 3 82 1.4E-28 T 12-10-2018 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 MIM_c25210 d30337a8a2871f2e06137056aea02fb8 98 Gene3D G3DSA:1.10.260.40 1 83 1.3E-28 T 12-10-2018 MIM_c25210 d30337a8a2871f2e06137056aea02fb8 98 SUPERFAMILY SSF47413 8 87 6.52E-20 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c31770 b0bb6441fa304c7c63baf8d5685dbf12 334 Gene3D G3DSA:3.40.190.150 38 324 1.1E-97 T 12-10-2018 MIM_c31770 b0bb6441fa304c7c63baf8d5685dbf12 334 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 57 330 5.0E-78 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c31770 b0bb6441fa304c7c63baf8d5685dbf12 334 SUPERFAMILY SSF53850 125 298 2.17E-10 T 12-10-2018 MIM_c31770 b0bb6441fa304c7c63baf8d5685dbf12 334 PIRSF PIRSF017082 3 334 2.4E-69 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c31770 b0bb6441fa304c7c63baf8d5685dbf12 334 Gene3D G3DSA:3.40.190.10 137 259 1.1E-97 T 12-10-2018 MIM_c31630 85caf2309386d457ea7bde34bce40569 215 SUPERFAMILY SSF46689 3 84 2.46E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c31630 85caf2309386d457ea7bde34bce40569 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 1.7E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c31630 85caf2309386d457ea7bde34bce40569 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 1.7E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c31630 85caf2309386d457ea7bde34bce40569 215 Gene3D G3DSA:1.10.357.10 5 195 1.7E-27 T 12-10-2018 MIM_c31630 85caf2309386d457ea7bde34bce40569 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 53 5.2E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c24690 f2f9ffa45be0c81810cba988fabf5e3b 494 ProSitePatterns PS01130 SLC26A transporters signature. 44 65 - T 12-10-2018 IPR018045 Sulphate anion transporter, conserved site GO:0008271|GO:0008272 Reactome: R-HSA-427601 MIM_c24690 f2f9ffa45be0c81810cba988fabf5e3b 494 SUPERFAMILY SSF52091 402 483 1.04E-9 T 12-10-2018 IPR036513 STAS domain superfamily MIM_c24690 f2f9ffa45be0c81810cba988fabf5e3b 494 Pfam PF01740 STAS domain 397 484 3.4E-7 T 12-10-2018 IPR002645 STAS domain MIM_c24690 f2f9ffa45be0c81810cba988fabf5e3b 494 Pfam PF00916 Sulfate permease family 154 356 1.1E-31 T 12-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MIM_c24690 f2f9ffa45be0c81810cba988fabf5e3b 494 Pfam PF00916 Sulfate permease family 16 145 6.9E-27 T 12-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MIM_c24690 f2f9ffa45be0c81810cba988fabf5e3b 494 Gene3D G3DSA:3.30.750.24 387 483 2.6E-25 T 12-10-2018 IPR036513 STAS domain superfamily MIM_c13350 3011c37d866f5978370d5af3a916c4a7 476 SUPERFAMILY SSF51905 1 348 6.48E-61 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c13350 3011c37d866f5978370d5af3a916c4a7 476 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 357 466 9.2E-39 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MIM_c13350 3011c37d866f5978370d5af3a916c4a7 476 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 303 325 8.3E-39 T 12-10-2018 MIM_c13350 3011c37d866f5978370d5af3a916c4a7 476 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 186 204 8.3E-39 T 12-10-2018 MIM_c13350 3011c37d866f5978370d5af3a916c4a7 476 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 8.3E-39 T 12-10-2018 MIM_c13350 3011c37d866f5978370d5af3a916c4a7 476 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 8.3E-39 T 12-10-2018 MIM_c13350 3011c37d866f5978370d5af3a916c4a7 476 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 274 290 8.3E-39 T 12-10-2018 MIM_c13350 3011c37d866f5978370d5af3a916c4a7 476 Gene3D G3DSA:3.50.50.60 166 288 6.2E-109 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c13350 3011c37d866f5978370d5af3a916c4a7 476 SUPERFAMILY SSF55424 353 474 2.41E-41 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MIM_c13350 3011c37d866f5978370d5af3a916c4a7 476 Gene3D G3DSA:3.30.390.30 356 476 1.4E-46 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MIM_c13350 3011c37d866f5978370d5af3a916c4a7 476 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 338 7.7E-67 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MIM_c13350 3011c37d866f5978370d5af3a916c4a7 476 Gene3D G3DSA:3.50.50.60 5 343 6.2E-109 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c13350 3011c37d866f5978370d5af3a916c4a7 476 PIRSF PIRSF000350 1 475 2.4E-81 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 MIM_c13350 3011c37d866f5978370d5af3a916c4a7 476 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 475 4.1E-161 T 12-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 MIM_c13350 3011c37d866f5978370d5af3a916c4a7 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 159 2.5E-75 T 12-10-2018 MIM_c13350 3011c37d866f5978370d5af3a916c4a7 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 353 374 2.5E-75 T 12-10-2018 MIM_c13350 3011c37d866f5978370d5af3a916c4a7 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 186 211 2.5E-75 T 12-10-2018 MIM_c13350 3011c37d866f5978370d5af3a916c4a7 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 440 460 2.5E-75 T 12-10-2018 MIM_c13350 3011c37d866f5978370d5af3a916c4a7 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 45 60 2.5E-75 T 12-10-2018 MIM_c13350 3011c37d866f5978370d5af3a916c4a7 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 418 433 2.5E-75 T 12-10-2018 MIM_c13350 3011c37d866f5978370d5af3a916c4a7 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.5E-75 T 12-10-2018 MIM_c13350 3011c37d866f5978370d5af3a916c4a7 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 289 2.5E-75 T 12-10-2018 MIM_c13350 3011c37d866f5978370d5af3a916c4a7 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 318 325 2.5E-75 T 12-10-2018 MIM_c18470 91583d3fa6ef1620fd5ffa1f77e4f420 85 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 77 8.9E-28 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c18470 91583d3fa6ef1620fd5ffa1f77e4f420 85 Pfam PF00886 Ribosomal protein S16 8 68 4.3E-24 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c18470 91583d3fa6ef1620fd5ffa1f77e4f420 85 Gene3D G3DSA:3.30.1320.10 1 84 5.5E-30 T 12-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c18470 91583d3fa6ef1620fd5ffa1f77e4f420 85 SUPERFAMILY SSF54565 1 76 2.49E-28 T 12-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c18470 91583d3fa6ef1620fd5ffa1f77e4f420 85 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 23.311 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c27490 8f6588dbbc75b2810214760aef5c25e2 243 Gene3D G3DSA:3.40.50.300 1 242 8.2E-80 T 12-10-2018 MIM_c27490 8f6588dbbc75b2810214760aef5c25e2 243 PIRSF PIRSF039085 1 241 5.3E-117 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MIM_c27490 8f6588dbbc75b2810214760aef5c25e2 243 SMART SM00382 26 213 5.3E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c27490 8f6588dbbc75b2810214760aef5c25e2 243 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c27490 8f6588dbbc75b2810214760aef5c25e2 243 SUPERFAMILY SSF52540 1 235 2.97E-80 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c27490 8f6588dbbc75b2810214760aef5c25e2 243 Pfam PF00005 ABC transporter 17 165 2.1E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c16720 79f9eb95c9f92529c8b33f227f22917d 358 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 MIM_c16720 79f9eb95c9f92529c8b33f227f22917d 358 SUPERFAMILY SSF53659 1 357 1.01E-120 T 12-10-2018 MIM_c16720 79f9eb95c9f92529c8b33f227f22917d 358 Gene3D G3DSA:3.40.718.10 1 357 4.8E-153 T 12-10-2018 MIM_c16720 79f9eb95c9f92529c8b33f227f22917d 358 SMART SM01329 4 353 1.0E-204 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MIM_c16720 79f9eb95c9f92529c8b33f227f22917d 358 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 357 50.9 T 12-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 MIM_c16720 79f9eb95c9f92529c8b33f227f22917d 358 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 353 1.4E-131 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MIM_c16720 79f9eb95c9f92529c8b33f227f22917d 358 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 5 352 1.0E-147 T 12-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 MIM_c14060 76d50a67bd64d36f5a9f7a98aeba15b4 93 SUPERFAMILY SSF47413 8 86 1.64E-22 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c14060 76d50a67bd64d36f5a9f7a98aeba15b4 93 Gene3D G3DSA:1.10.260.40 1 90 3.2E-28 T 12-10-2018 MIM_c14060 76d50a67bd64d36f5a9f7a98aeba15b4 93 SMART SM00530 12 65 2.9E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c14060 76d50a67bd64d36f5a9f7a98aeba15b4 93 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 3 80 8.7E-28 T 12-10-2018 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 MIM_c14060 76d50a67bd64d36f5a9f7a98aeba15b4 93 Pfam PF01381 Helix-turn-helix 20 61 5.8E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c16360 3eeea99d8d9ecb04cd7d3f286075ed27 597 Gene3D G3DSA:2.40.110.10 159 292 1.7E-24 T 12-10-2018 MIM_c16360 3eeea99d8d9ecb04cd7d3f286075ed27 597 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 41 155 8.8E-13 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c16360 3eeea99d8d9ecb04cd7d3f286075ed27 597 Gene3D G3DSA:1.20.140.10 293 459 2.9E-44 T 12-10-2018 MIM_c16360 3eeea99d8d9ecb04cd7d3f286075ed27 597 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 161 266 3.2E-15 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MIM_c16360 3eeea99d8d9ecb04cd7d3f286075ed27 597 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 289 452 8.4E-22 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MIM_c16360 3eeea99d8d9ecb04cd7d3f286075ed27 597 Gene3D G3DSA:1.10.540.10 16 157 7.6E-17 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c16360 3eeea99d8d9ecb04cd7d3f286075ed27 597 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 470 587 1.1E-20 T 12-10-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain MIM_c16360 3eeea99d8d9ecb04cd7d3f286075ed27 597 SUPERFAMILY SSF56645 38 267 6.68E-54 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c16360 3eeea99d8d9ecb04cd7d3f286075ed27 597 SUPERFAMILY SSF47203 292 470 5.64E-40 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c38830 0978e97a7fbf597e1f31caaf3bac2813 235 Gene3D G3DSA:2.60.120.10 2 157 7.8E-18 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c38830 0978e97a7fbf597e1f31caaf3bac2813 235 SUPERFAMILY SSF46785 157 231 4.44E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c38830 0978e97a7fbf597e1f31caaf3bac2813 235 Pfam PF13545 Crp-like helix-turn-helix domain 159 230 5.1E-13 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MIM_c38830 0978e97a7fbf597e1f31caaf3bac2813 235 Gene3D G3DSA:1.10.10.10 158 232 9.6E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c38830 0978e97a7fbf597e1f31caaf3bac2813 235 Pfam PF00027 Cyclic nucleotide-binding domain 41 125 9.9E-13 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain MIM_c38830 0978e97a7fbf597e1f31caaf3bac2813 235 SMART SM00100 21 142 3.2E-4 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain MIM_c38830 0978e97a7fbf597e1f31caaf3bac2813 235 SUPERFAMILY SSF51206 15 150 3.54E-25 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like MIM_c08900 79c7a1866cce5f80b41612fa042cb65c 286 SUPERFAMILY SSF103481 39 138 2.88E-9 T 12-10-2018 MIM_c08900 79c7a1866cce5f80b41612fa042cb65c 286 Pfam PF00892 EamA-like transporter family 149 276 2.4E-17 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MIM_c08900 79c7a1866cce5f80b41612fa042cb65c 286 Pfam PF00892 EamA-like transporter family 6 137 1.2E-13 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MIM_c08900 79c7a1866cce5f80b41612fa042cb65c 286 SUPERFAMILY SSF103481 185 277 2.09E-14 T 12-10-2018 MIM_c21490 d70e30b3955e0b82cc371528c01fdb53 533 Pfam PF00005 ABC transporter 339 468 2.4E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c21490 d70e30b3955e0b82cc371528c01fdb53 533 ProSitePatterns PS00211 ABC transporters family signature. 440 454 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c21490 d70e30b3955e0b82cc371528c01fdb53 533 Pfam PF00005 ABC transporter 18 184 1.7E-19 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c21490 d70e30b3955e0b82cc371528c01fdb53 533 SUPERFAMILY SSF52540 6 237 2.79E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c21490 d70e30b3955e0b82cc371528c01fdb53 533 SMART SM00382 345 514 3.4E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c21490 d70e30b3955e0b82cc371528c01fdb53 533 SMART SM00382 26 238 5.6E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c21490 d70e30b3955e0b82cc371528c01fdb53 533 Gene3D G3DSA:3.40.50.300 4 279 5.1E-58 T 12-10-2018 MIM_c21490 d70e30b3955e0b82cc371528c01fdb53 533 Pfam PF12848 ABC transporter 224 311 9.6E-19 T 12-10-2018 IPR032781 ABC-transporter extension domain MIM_c21490 d70e30b3955e0b82cc371528c01fdb53 533 Gene3D G3DSA:3.40.50.300 282 533 8.1E-53 T 12-10-2018 MIM_c21490 d70e30b3955e0b82cc371528c01fdb53 533 SUPERFAMILY SSF52540 296 525 8.74E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c16030 1fc3eb29f3229ed535c81fdf30267865 400 Pfam PF00487 Fatty acid desaturase 17 219 1.3E-10 T 12-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 MIM_c16030 1fc3eb29f3229ed535c81fdf30267865 400 Pfam PF01610 Transposase 282 399 1.3E-8 T 12-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain MIM_c08240 89a9b3ccb53a482e077d17feb65ac201 407 Gene3D G3DSA:3.40.50.10540 4 389 3.5E-123 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c08240 89a9b3ccb53a482e077d17feb65ac201 407 SUPERFAMILY SSF89796 1 395 1.09E-128 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c08240 89a9b3ccb53a482e077d17feb65ac201 407 Gene3D G3DSA:3.30.1540.10 231 322 3.5E-123 T 12-10-2018 MIM_c08240 89a9b3ccb53a482e077d17feb65ac201 407 Pfam PF02515 CoA-transferase family III 5 372 3.1E-122 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 MIM_c22150 f5ed77bce0f65529d4faf4d65505566f 261 Gene3D G3DSA:2.60.260.20 16 76 2.0E-14 T 12-10-2018 MIM_c22150 f5ed77bce0f65529d4faf4d65505566f 261 Gene3D G3DSA:3.30.70.790 78 148 1.3E-25 T 12-10-2018 IPR036675 UreE, C-terminal domain superfamily GO:0016151|GO:0019627|GO:0065003 MIM_c22150 f5ed77bce0f65529d4faf4d65505566f 261 Pfam PF05194 UreE urease accessory protein, C-terminal domain 78 191 1.4E-10 T 12-10-2018 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0016151|GO:0019627|GO:0065003 MIM_c22150 f5ed77bce0f65529d4faf4d65505566f 261 SUPERFAMILY SSF69287 20 77 6.54E-12 T 12-10-2018 IPR036118 UreE urease accessory, N-terminal domain superfamily MIM_c22150 f5ed77bce0f65529d4faf4d65505566f 261 SUPERFAMILY SSF69737 77 144 9.55E-20 T 12-10-2018 IPR036675 UreE, C-terminal domain superfamily GO:0016151|GO:0019627|GO:0065003 MIM_c22150 f5ed77bce0f65529d4faf4d65505566f 261 Hamap MF_00822 Urease accessory protein UreE [ureE]. 3 145 21.448 T 12-10-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 MIM_c22150 f5ed77bce0f65529d4faf4d65505566f 261 SMART SM00988 7 71 8.0E-10 T 12-10-2018 IPR004029 UreE urease accessory, N-terminal MIM_c22150 f5ed77bce0f65529d4faf4d65505566f 261 Pfam PF02814 UreE urease accessory protein, N-terminal domain 26 71 1.3E-11 T 12-10-2018 IPR004029 UreE urease accessory, N-terminal MIM_c25040 886e0a2c345eea187f5db7d3202edd9a 205 Gene3D G3DSA:1.10.357.10 3 201 7.7E-50 T 12-10-2018 MIM_c25040 886e0a2c345eea187f5db7d3202edd9a 205 SUPERFAMILY SSF48498 84 196 3.14E-21 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MIM_c25040 886e0a2c345eea187f5db7d3202edd9a 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 5.8E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c25040 886e0a2c345eea187f5db7d3202edd9a 205 SUPERFAMILY SSF46689 5 76 8.72E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c25040 886e0a2c345eea187f5db7d3202edd9a 205 Pfam PF16925 Bacterial transcriptional repressor C-terminal 86 194 3.5E-18 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MIM_c18800 6ff8f823c4ecc721d72d7f85be20fe0c 185 Hamap MF_00105 Transcription elongation factor GreA [greA]. 28 181 27.389 T 12-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 MIM_c18800 6ff8f823c4ecc721d72d7f85be20fe0c 185 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 109 182 7.7E-24 T 12-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MIM_c18800 6ff8f823c4ecc721d72d7f85be20fe0c 185 Hamap MF_00930 Transcription elongation factor GreB [greB]. 27 183 49.265 T 12-10-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 MIM_c18800 6ff8f823c4ecc721d72d7f85be20fe0c 185 Pfam PF03449 Transcription elongation factor, N-terminal 30 100 9.2E-25 T 12-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 MIM_c18800 6ff8f823c4ecc721d72d7f85be20fe0c 185 Gene3D G3DSA:3.10.50.30 105 184 4.2E-24 T 12-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 MIM_c18800 6ff8f823c4ecc721d72d7f85be20fe0c 185 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 146 162 - T 12-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 MIM_c18800 6ff8f823c4ecc721d72d7f85be20fe0c 185 SUPERFAMILY SSF46557 29 104 7.06E-27 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 MIM_c18800 6ff8f823c4ecc721d72d7f85be20fe0c 185 SUPERFAMILY SSF54534 107 182 6.15E-20 T 12-10-2018 MIM_c18800 6ff8f823c4ecc721d72d7f85be20fe0c 185 PIRSF PIRSF006092 26 184 4.3E-44 T 12-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 MIM_c18800 6ff8f823c4ecc721d72d7f85be20fe0c 185 Gene3D G3DSA:1.10.287.180 28 102 6.2E-28 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 MIM_c18800 6ff8f823c4ecc721d72d7f85be20fe0c 185 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 43 74 - T 12-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 MIM_c18800 6ff8f823c4ecc721d72d7f85be20fe0c 185 TIGRFAM TIGR01461 greB: transcription elongation factor GreB 29 183 1.2E-63 T 12-10-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 MIM_c18730 aaade584ebf6978ed42530df6dbbe1fa 201 Gene3D G3DSA:3.30.1330.60 57 201 9.9E-42 T 12-10-2018 IPR036737 OmpA-like domain superfamily MIM_c18730 aaade584ebf6978ed42530df6dbbe1fa 201 SUPERFAMILY SSF103088 82 199 6.41E-35 T 12-10-2018 IPR036737 OmpA-like domain superfamily MIM_c18730 aaade584ebf6978ed42530df6dbbe1fa 201 PRINTS PR01021 OMPA domain signature 124 139 6.9E-16 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MIM_c18730 aaade584ebf6978ed42530df6dbbe1fa 201 PRINTS PR01021 OMPA domain signature 94 116 6.9E-16 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MIM_c18730 aaade584ebf6978ed42530df6dbbe1fa 201 PRINTS PR01021 OMPA domain signature 139 155 6.9E-16 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MIM_c18730 aaade584ebf6978ed42530df6dbbe1fa 201 Pfam PF00691 OmpA family 93 182 3.0E-23 T 12-10-2018 IPR006665 OmpA-like domain MIM_c28550 803264c4aa179d167794fe5ddc37e6fd 957 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 243 292 1.0E-15 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c28550 803264c4aa179d167794fe5ddc37e6fd 957 PIRSF PIRSF036643 18 954 0.0 T 12-10-2018 MIM_c28550 803264c4aa179d167794fe5ddc37e6fd 957 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 245 920 1.8E-279 T 12-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 MIM_c28550 803264c4aa179d167794fe5ddc37e6fd 957 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 21 97 2.5E-22 T 12-10-2018 MIM_c28550 803264c4aa179d167794fe5ddc37e6fd 957 SUPERFAMILY SSF53706 241 770 2.09E-192 T 12-10-2018 MIM_c28550 803264c4aa179d167794fe5ddc37e6fd 957 SMART SM00929 104 144 1.8E-18 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c28550 803264c4aa179d167794fe5ddc37e6fd 957 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 104 143 1.1E-16 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c28550 803264c4aa179d167794fe5ddc37e6fd 957 Gene3D G3DSA:3.40.50.740 302 771 1.8E-169 T 12-10-2018 MIM_c28550 803264c4aa179d167794fe5ddc37e6fd 957 Gene3D G3DSA:2.40.40.20 809 923 1.8E-34 T 12-10-2018 MIM_c28550 803264c4aa179d167794fe5ddc37e6fd 957 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 213 224 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MIM_c28550 803264c4aa179d167794fe5ddc37e6fd 957 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 850 877 - T 12-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 MIM_c28550 803264c4aa179d167794fe5ddc37e6fd 957 SUPERFAMILY SSF54862 96 235 9.21E-38 T 12-10-2018 MIM_c28550 803264c4aa179d167794fe5ddc37e6fd 957 Pfam PF01568 Molydopterin dinucleotide binding domain 812 916 4.6E-27 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 MIM_c28550 803264c4aa179d167794fe5ddc37e6fd 957 Pfam PF00037 4Fe-4S binding domain 211 226 2.4E-5 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MIM_c28550 803264c4aa179d167794fe5ddc37e6fd 957 Gene3D G3DSA:2.20.25.90 241 293 6.0E-17 T 12-10-2018 MIM_c28550 803264c4aa179d167794fe5ddc37e6fd 957 Gene3D G3DSA:3.10.20.740 22 143 6.6E-40 T 12-10-2018 MIM_c28550 803264c4aa179d167794fe5ddc37e6fd 957 SUPERFAMILY SSF54292 23 95 1.91E-18 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MIM_c28550 803264c4aa179d167794fe5ddc37e6fd 957 Gene3D G3DSA:3.30.70.20 149 231 2.0E-23 T 12-10-2018 MIM_c28550 803264c4aa179d167794fe5ddc37e6fd 957 Pfam PF00384 Molybdopterin oxidoreductase 297 728 1.9E-75 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c28550 803264c4aa179d167794fe5ddc37e6fd 957 Gene3D G3DSA:3.40.228.10 377 584 1.8E-169 T 12-10-2018 MIM_c28550 803264c4aa179d167794fe5ddc37e6fd 957 SUPERFAMILY SSF50692 768 923 2.94E-40 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily MIM_c28550 803264c4aa179d167794fe5ddc37e6fd 957 SMART SM00926 240 294 1.8E-15 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c04970 76ecf7f9d4001b2ed931b1eea2d7c34c 151 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 15 28 - T 12-10-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site MIM_c04970 76ecf7f9d4001b2ed931b1eea2d7c34c 151 Gene3D G3DSA:1.10.1200.120 5 149 6.0E-38 T 12-10-2018 IPR036019 Gated mechanosensitive channel MIM_c04970 76ecf7f9d4001b2ed931b1eea2d7c34c 151 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 5 148 2.3E-32 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 MIM_c04970 76ecf7f9d4001b2ed931b1eea2d7c34c 151 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 5 145 1.2E-40 T 12-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L MIM_c04970 76ecf7f9d4001b2ed931b1eea2d7c34c 151 SUPERFAMILY SSF81330 14 142 1.12E-30 T 12-10-2018 IPR036019 Gated mechanosensitive channel MIM_c04970 76ecf7f9d4001b2ed931b1eea2d7c34c 151 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 5 147 22.87 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 MIM_c04970 76ecf7f9d4001b2ed931b1eea2d7c34c 151 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 98 106 9.1E-8 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 MIM_c04970 76ecf7f9d4001b2ed931b1eea2d7c34c 151 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 8 22 9.1E-8 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 MIM_c04970 76ecf7f9d4001b2ed931b1eea2d7c34c 151 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 107 116 9.1E-8 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 MIM_c17200 314429654452f8945d94a3f042f7d398 233 Gene3D G3DSA:3.40.50.2300 1 121 3.4E-30 T 12-10-2018 MIM_c17200 314429654452f8945d94a3f042f7d398 233 Gene3D G3DSA:1.10.10.10 122 229 4.3E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c17200 314429654452f8945d94a3f042f7d398 233 Pfam PF00072 Response regulator receiver domain 5 115 2.1E-20 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c17200 314429654452f8945d94a3f042f7d398 233 SMART SM00862 148 223 1.6E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MIM_c17200 314429654452f8945d94a3f042f7d398 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 223 1.5E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MIM_c17200 314429654452f8945d94a3f042f7d398 233 SMART SM00448 2 114 3.3E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c17200 314429654452f8945d94a3f042f7d398 233 SUPERFAMILY SSF52172 1 181 1.11E-34 T 12-10-2018 IPR011006 CheY-like superfamily MIM_c01730 98d18048956dc98f728d39e5327cc09a 581 Pfam PF00920 Dehydratase family 41 564 5.8E-171 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MIM_c01730 98d18048956dc98f728d39e5327cc09a 581 Gene3D G3DSA:3.50.30.80 384 538 9.1E-48 T 12-10-2018 MIM_c01730 98d18048956dc98f728d39e5327cc09a 581 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 124 134 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MIM_c01730 98d18048956dc98f728d39e5327cc09a 581 SUPERFAMILY SSF52016 385 567 6.28E-56 T 12-10-2018 MIM_c01730 98d18048956dc98f728d39e5327cc09a 581 SUPERFAMILY SSF143975 4 372 1.06E-116 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MIM_c39890 b77163d2a1b4f1202320b9d64b88a0b6 375 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 334 349 2.9E-25 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MIM_c39890 b77163d2a1b4f1202320b9d64b88a0b6 375 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 28 44 2.9E-25 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MIM_c39890 b77163d2a1b4f1202320b9d64b88a0b6 375 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 69 87 2.9E-25 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MIM_c39890 b77163d2a1b4f1202320b9d64b88a0b6 375 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 282 295 2.9E-25 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MIM_c39890 b77163d2a1b4f1202320b9d64b88a0b6 375 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 50 66 2.9E-25 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MIM_c39890 b77163d2a1b4f1202320b9d64b88a0b6 375 Gene3D G3DSA:3.40.50.2300 147 277 5.8E-108 T 12-10-2018 MIM_c39890 b77163d2a1b4f1202320b9d64b88a0b6 375 Pfam PF13458 Periplasmic binding protein 27 367 3.9E-62 T 12-10-2018 IPR028081 Leucine-binding protein domain MIM_c39890 b77163d2a1b4f1202320b9d64b88a0b6 375 SUPERFAMILY SSF53822 26 372 7.36E-94 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c39890 b77163d2a1b4f1202320b9d64b88a0b6 375 Gene3D G3DSA:3.40.50.2300 29 350 5.8E-108 T 12-10-2018 MIM_c14860 ccbcd6f2a2945989c4b61d810b7ab8d5 151 SUPERFAMILY SSF55653 59 149 4.05E-23 T 12-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily MIM_c14860 ccbcd6f2a2945989c4b61d810b7ab8d5 151 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 148 1.8E-42 T 12-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c14860 ccbcd6f2a2945989c4b61d810b7ab8d5 151 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 149 25.146 T 12-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c14860 ccbcd6f2a2945989c4b61d810b7ab8d5 151 SUPERFAMILY SSF55658 1 56 4.36E-17 T 12-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal MIM_c14860 ccbcd6f2a2945989c4b61d810b7ab8d5 151 Gene3D G3DSA:3.10.430.100 61 149 3.7E-25 T 12-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily MIM_c14860 ccbcd6f2a2945989c4b61d810b7ab8d5 151 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 1.9E-20 T 12-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c14860 ccbcd6f2a2945989c4b61d810b7ab8d5 151 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 12-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c14860 ccbcd6f2a2945989c4b61d810b7ab8d5 151 Gene3D G3DSA:3.40.5.10 1 59 2.9E-21 T 12-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c14860 ccbcd6f2a2945989c4b61d810b7ab8d5 151 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 147 1.7E-24 T 12-10-2018 IPR020069 Ribosomal protein L9, C-terminal MIM_c36860 9979cbd43d8eebb5a8cef8836d287535 147 Pfam PF16695 Type VI secretion system (T6SS), amidase immunity protein 53 139 4.1E-22 T 12-10-2018 IPR032032 Type VI secretion system (T6SS), amidase immunity protein MIM_c36860 9979cbd43d8eebb5a8cef8836d287535 147 Gene3D G3DSA:1.20.120.1620 42 145 3.1E-32 T 12-10-2018 IPR038314 T6SS superfamily MIM_c16070 6b49d3d9af6698f0be5cc4c104e7ef4d 143 Pfam PF03061 Thioesterase superfamily 48 122 1.1E-12 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MIM_c16070 6b49d3d9af6698f0be5cc4c104e7ef4d 143 SUPERFAMILY SSF54637 4 140 1.16E-26 T 12-10-2018 IPR029069 HotDog domain superfamily MIM_c16070 6b49d3d9af6698f0be5cc4c104e7ef4d 143 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 18 117 3.9E-16 T 12-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 MIM_c16070 6b49d3d9af6698f0be5cc4c104e7ef4d 143 Gene3D G3DSA:3.10.129.10 1 139 1.4E-29 T 12-10-2018 MIM_c22070 3e3baea0066eb14c45095815e5d46216 381 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 48 360 3.6E-128 T 12-10-2018 IPR017778 ABC transporter, urea, permease protein, UrtC MIM_c22070 3e3baea0066eb14c45095815e5d46216 381 Pfam PF02653 Branched-chain amino acid transport system / permease component 56 349 7.7E-40 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c08860 c8b8bcf35117f4695c704d0913951b5f 423 SUPERFAMILY SSF103473 6 410 3.66E-36 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c08860 c8b8bcf35117f4695c704d0913951b5f 423 Gene3D G3DSA:1.20.1250.20 213 410 2.8E-11 T 12-10-2018 MIM_c08860 c8b8bcf35117f4695c704d0913951b5f 423 Gene3D G3DSA:1.20.1250.20 12 202 1.6E-13 T 12-10-2018 MIM_c08860 c8b8bcf35117f4695c704d0913951b5f 423 Pfam PF07690 Major Facilitator Superfamily 18 311 1.2E-21 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c22230 c826d115db169dc77b287f0d5e8dfa69 192 Gene3D G3DSA:3.30.420.270 62 133 9.5E-8 T 12-10-2018 MIM_c22230 c826d115db169dc77b287f0d5e8dfa69 192 Pfam PF02472 Biopolymer transport protein ExbD/TolR 16 137 1.8E-29 T 12-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 MIM_c35440 5e9e77135dfcd03e21a394a381db984b 659 SUPERFAMILY SSF56300 144 558 1.73E-7 T 12-10-2018 MIM_c35440 5e9e77135dfcd03e21a394a381db984b 659 Pfam PF09423 PhoD-like phosphatase 310 583 4.7E-8 T 12-10-2018 IPR018946 Alkaline phosphatase D-related MIM_c35440 5e9e77135dfcd03e21a394a381db984b 659 Gene3D G3DSA:3.60.21.70 288 562 1.8E-7 T 12-10-2018 IPR038607 PhoD-like superfamily MIM_c39520 9ac0febfcc9e7ac65d4dc96431df2bc9 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.2E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c39520 9ac0febfcc9e7ac65d4dc96431df2bc9 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.2E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c39520 9ac0febfcc9e7ac65d4dc96431df2bc9 248 SUPERFAMILY SSF46785 6 78 4.03E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c39520 9ac0febfcc9e7ac65d4dc96431df2bc9 248 Pfam PF07729 FCD domain 99 222 1.2E-28 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c39520 9ac0febfcc9e7ac65d4dc96431df2bc9 248 SUPERFAMILY SSF48008 95 228 4.97E-30 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c39520 9ac0febfcc9e7ac65d4dc96431df2bc9 248 SMART SM00345 15 74 4.3E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c39520 9ac0febfcc9e7ac65d4dc96431df2bc9 248 Gene3D G3DSA:1.20.120.530 95 231 1.6E-30 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c39520 9ac0febfcc9e7ac65d4dc96431df2bc9 248 SMART SM00895 99 223 1.8E-25 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c39520 9ac0febfcc9e7ac65d4dc96431df2bc9 248 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 8.1E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c39520 9ac0febfcc9e7ac65d4dc96431df2bc9 248 Gene3D G3DSA:1.10.10.10 5 78 3.2E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c26050 4ec0e4a57d1fd9b7ea4192c2f50f9653 212 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 203 1.1E-52 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MIM_c26050 4ec0e4a57d1fd9b7ea4192c2f50f9653 212 Gene3D G3DSA:3.40.50.1240 1 210 9.3E-54 T 12-10-2018 IPR029033 Histidine phosphatase superfamily MIM_c26050 4ec0e4a57d1fd9b7ea4192c2f50f9653 212 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 8 17 - T 12-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 MIM_c26050 4ec0e4a57d1fd9b7ea4192c2f50f9653 212 PIRSF PIRSF000709 1 99 3.5E-8 T 12-10-2018 MIM_c26050 4ec0e4a57d1fd9b7ea4192c2f50f9653 212 SUPERFAMILY SSF53254 1 209 1.83E-53 T 12-10-2018 IPR029033 Histidine phosphatase superfamily MIM_c26050 4ec0e4a57d1fd9b7ea4192c2f50f9653 212 SMART SM00855 5 162 5.0E-24 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MIM_c28680 93e02f6376711fabdcb872b0bbbcac4d 583 Gene3D G3DSA:1.10.530.10 77 222 1.5E-32 T 12-10-2018 MIM_c28680 93e02f6376711fabdcb872b0bbbcac4d 583 SMART SM00257 534 577 2.5E-9 T 12-10-2018 IPR018392 LysM domain MIM_c28680 93e02f6376711fabdcb872b0bbbcac4d 583 SMART SM00257 306 351 2.7 T 12-10-2018 IPR018392 LysM domain MIM_c28680 93e02f6376711fabdcb872b0bbbcac4d 583 SUPERFAMILY SSF53955 79 229 1.97E-40 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily MIM_c28680 93e02f6376711fabdcb872b0bbbcac4d 583 Pfam PF01476 LysM domain 311 337 1.7E-4 T 12-10-2018 IPR018392 LysM domain MIM_c28680 93e02f6376711fabdcb872b0bbbcac4d 583 Pfam PF01476 LysM domain 537 577 2.4E-10 T 12-10-2018 IPR018392 LysM domain MIM_c28680 93e02f6376711fabdcb872b0bbbcac4d 583 Gene3D G3DSA:3.10.350.10 533 577 5.5E-12 T 12-10-2018 IPR036779 LysM domain superfamily MIM_c28680 93e02f6376711fabdcb872b0bbbcac4d 583 SUPERFAMILY SSF54106 534 577 1.03E-8 T 12-10-2018 MIM_c28680 93e02f6376711fabdcb872b0bbbcac4d 583 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 100 128 - T 12-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 MIM_c28680 93e02f6376711fabdcb872b0bbbcac4d 583 Pfam PF01464 Transglycosylase SLT domain 85 188 3.0E-23 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 MIM_c40270 4629311f2cf4ad1543f5451b1b6bbd24 315 PRINTS PR00116 Arginase signature 178 196 8.5E-42 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 MIM_c40270 4629311f2cf4ad1543f5451b1b6bbd24 315 PRINTS PR00116 Arginase signature 226 255 8.5E-42 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 MIM_c40270 4629311f2cf4ad1543f5451b1b6bbd24 315 PRINTS PR00116 Arginase signature 97 112 8.5E-42 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 MIM_c40270 4629311f2cf4ad1543f5451b1b6bbd24 315 PRINTS PR00116 Arginase signature 261 275 8.5E-42 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 MIM_c40270 4629311f2cf4ad1543f5451b1b6bbd24 315 PRINTS PR00116 Arginase signature 124 151 8.5E-42 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 MIM_c40270 4629311f2cf4ad1543f5451b1b6bbd24 315 Gene3D G3DSA:3.40.800.10 6 304 2.0E-92 T 12-10-2018 MIM_c40270 4629311f2cf4ad1543f5451b1b6bbd24 315 TIGRFAM TIGR01229 rocF_arginase: arginase 9 303 3.8E-86 T 12-10-2018 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 MIM_c40270 4629311f2cf4ad1543f5451b1b6bbd24 315 SUPERFAMILY SSF52768 7 303 7.02E-87 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily MIM_c40270 4629311f2cf4ad1543f5451b1b6bbd24 315 Pfam PF00491 Arginase family 7 299 2.2E-76 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 MIM_c40270 4629311f2cf4ad1543f5451b1b6bbd24 315 ProSitePatterns PS01053 Arginase family signature. 229 250 - T 12-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 MIM_c40270 4629311f2cf4ad1543f5451b1b6bbd24 315 PIRSF PIRSF036979 2 304 5.0E-32 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 MIM_c02740 670946969ea9e2470c037a559e2417b8 833 SUPERFAMILY SSF56235 39 830 2.5E-198 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MIM_c02740 670946969ea9e2470c037a559e2417b8 833 Gene3D G3DSA:1.10.439.10 16 178 1.4E-42 T 12-10-2018 IPR023343 Penicillin amidase type, domain 1 GO:0016811 MIM_c02740 670946969ea9e2470c037a559e2417b8 833 Gene3D G3DSA:1.10.1400.10 589 714 4.2E-154 T 12-10-2018 MIM_c02740 670946969ea9e2470c037a559e2417b8 833 Gene3D G3DSA:3.60.20.10 298 805 4.2E-154 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MIM_c02740 670946969ea9e2470c037a559e2417b8 833 Pfam PF01804 Penicillin amidase 45 818 1.1E-205 T 12-10-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 MIM_c02740 670946969ea9e2470c037a559e2417b8 833 PIRSF PIRSF001227 3 830 2.3E-206 T 12-10-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 MIM_c02740 670946969ea9e2470c037a559e2417b8 833 Gene3D G3DSA:2.30.120.10 370 438 4.2E-154 T 12-10-2018 MIM_c33680 8d7344419e00a4a838531a689ea369ea 401 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 21 390 3.4E-63 T 12-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 MIM_c33680 8d7344419e00a4a838531a689ea369ea 401 Pfam PF07690 Major Facilitator Superfamily 33 363 1.1E-38 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c33680 8d7344419e00a4a838531a689ea369ea 401 SUPERFAMILY SSF103473 20 396 7.85E-53 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c33680 8d7344419e00a4a838531a689ea369ea 401 Gene3D G3DSA:1.20.1720.10 22 399 1.7E-83 T 12-10-2018 MIM_c00140 3a8a95196e16645582fcd24ab2422286 396 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 44 372 2.9E-78 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MIM_c00140 3a8a95196e16645582fcd24ab2422286 396 SUPERFAMILY SSF111369 58 303 3.66E-67 T 12-10-2018 MIM_c00140 3a8a95196e16645582fcd24ab2422286 396 Gene3D G3DSA:1.10.287.470 103 176 2.0E-94 T 12-10-2018 MIM_c00140 3a8a95196e16645582fcd24ab2422286 396 Gene3D G3DSA:2.40.420.20 310 373 2.0E-94 T 12-10-2018 MIM_c00140 3a8a95196e16645582fcd24ab2422286 396 Gene3D G3DSA:2.40.30.170 56 309 2.0E-94 T 12-10-2018 MIM_c00140 3a8a95196e16645582fcd24ab2422286 396 Gene3D G3DSA:2.40.50.100 68 213 2.0E-94 T 12-10-2018 MIM_c00140 3a8a95196e16645582fcd24ab2422286 396 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 65 299 4.4E-16 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MIM_c09660 d3e4c4045977cf6bc24e8f4737066570 226 Pfam PF01596 O-methyltransferase 39 185 2.9E-35 T 12-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 MIM_c09660 d3e4c4045977cf6bc24e8f4737066570 226 Gene3D G3DSA:3.40.50.150 6 226 1.4E-64 T 12-10-2018 MIM_c09660 d3e4c4045977cf6bc24e8f4737066570 226 SUPERFAMILY SSF53335 40 224 1.16E-34 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c34670 32f2fdaabc6aab991e762e1f98870b14 253 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 18 243 1.3E-55 T 12-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 MIM_c34670 32f2fdaabc6aab991e762e1f98870b14 253 SUPERFAMILY SSF51621 4 251 9.07E-78 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MIM_c34670 32f2fdaabc6aab991e762e1f98870b14 253 Gene3D G3DSA:3.20.20.60 1 253 3.3E-81 T 12-10-2018 MIM_c16990 89591bf46f759ba9caa48d5da6d2d4d4 233 Pfam PF02308 MgtC family 11 139 5.6E-38 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MIM_c16990 89591bf46f759ba9caa48d5da6d2d4d4 233 PRINTS PR01837 MgtC/SapB protein signature 14 33 2.2E-43 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MIM_c16990 89591bf46f759ba9caa48d5da6d2d4d4 233 PRINTS PR01837 MgtC/SapB protein signature 33 51 2.2E-43 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MIM_c16990 89591bf46f759ba9caa48d5da6d2d4d4 233 PRINTS PR01837 MgtC/SapB protein signature 66 88 2.2E-43 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MIM_c16990 89591bf46f759ba9caa48d5da6d2d4d4 233 PRINTS PR01837 MgtC/SapB protein signature 93 117 2.2E-43 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MIM_c19620 fc3d2898a21d48f91082b7353f258933 255 PIRSF PIRSF005902 1 255 1.9E-79 T 12-10-2018 IPR001130 TatD family GO:0016788 MIM_c19620 fc3d2898a21d48f91082b7353f258933 255 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 188 204 - T 12-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 MIM_c19620 fc3d2898a21d48f91082b7353f258933 255 Pfam PF01026 TatD related DNase 3 252 4.4E-77 T 12-10-2018 IPR001130 TatD family GO:0016788 MIM_c19620 fc3d2898a21d48f91082b7353f258933 255 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 12-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 MIM_c19620 fc3d2898a21d48f91082b7353f258933 255 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 252 9.2E-84 T 12-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 MIM_c19620 fc3d2898a21d48f91082b7353f258933 255 Gene3D G3DSA:3.20.20.140 1 255 4.2E-91 T 12-10-2018 MIM_c19620 fc3d2898a21d48f91082b7353f258933 255 SUPERFAMILY SSF51556 2 252 5.01E-88 T 12-10-2018 IPR032466 Metal-dependent hydrolase MIM_c05550 87d6fe341047cbbb40dd0f2839bda39f 263 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c05550 87d6fe341047cbbb40dd0f2839bda39f 263 Gene3D G3DSA:3.40.50.300 18 263 1.5E-67 T 12-10-2018 MIM_c05550 87d6fe341047cbbb40dd0f2839bda39f 263 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 20 263 2.5E-115 T 12-10-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 MIM_c05550 87d6fe341047cbbb40dd0f2839bda39f 263 Pfam PF00005 ABC transporter 36 188 4.4E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c05550 87d6fe341047cbbb40dd0f2839bda39f 263 SMART SM00382 44 238 1.4E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c05550 87d6fe341047cbbb40dd0f2839bda39f 263 SUPERFAMILY SSF52540 20 259 6.29E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c05550 87d6fe341047cbbb40dd0f2839bda39f 263 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 236 258 4.2E-5 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal MIM_c29960 f8088210b47418b8b1f62871363130b6 146 Gene3D G3DSA:3.30.420.270 59 130 4.8E-10 T 12-10-2018 MIM_c29960 f8088210b47418b8b1f62871363130b6 146 Pfam PF02472 Biopolymer transport protein ExbD/TolR 13 138 3.8E-25 T 12-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 MIM_c39460 4b389f29653a00ff716ce81b5a9dae89 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c39460 4b389f29653a00ff716ce81b5a9dae89 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 5.4E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c39460 4b389f29653a00ff716ce81b5a9dae89 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 5.4E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c39460 4b389f29653a00ff716ce81b5a9dae89 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 5.4E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c39460 4b389f29653a00ff716ce81b5a9dae89 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 5.4E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c39460 4b389f29653a00ff716ce81b5a9dae89 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 5.4E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c39460 4b389f29653a00ff716ce81b5a9dae89 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 5.4E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c39460 4b389f29653a00ff716ce81b5a9dae89 250 Gene3D G3DSA:3.40.50.720 1 249 1.2E-81 T 12-10-2018 MIM_c39460 4b389f29653a00ff716ce81b5a9dae89 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.0E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c39460 4b389f29653a00ff716ce81b5a9dae89 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.0E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c39460 4b389f29653a00ff716ce81b5a9dae89 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.0E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c39460 4b389f29653a00ff716ce81b5a9dae89 250 SUPERFAMILY SSF51735 5 247 4.97E-78 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c39460 4b389f29653a00ff716ce81b5a9dae89 250 Pfam PF00106 short chain dehydrogenase 10 200 6.1E-58 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c12510 1bb2eec3d5f8ae04a4cd2c1fc1c7706a 224 SUPERFAMILY SSF100950 2 221 3.0E-75 T 12-10-2018 IPR037171 NagB/RpiA transferase-like MIM_c12510 1bb2eec3d5f8ae04a4cd2c1fc1c7706a 224 Pfam PF01144 Coenzyme A transferase 8 218 2.2E-63 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MIM_c12510 1bb2eec3d5f8ae04a4cd2c1fc1c7706a 224 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 218 5.8E-100 T 12-10-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 MIM_c12510 1bb2eec3d5f8ae04a4cd2c1fc1c7706a 224 Gene3D G3DSA:3.40.1080.10 1 219 2.3E-78 T 12-10-2018 MIM_c12510 1bb2eec3d5f8ae04a4cd2c1fc1c7706a 224 SMART SM00882 6 219 4.3E-74 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MIM_c20950 41ecc3445af603bc8064c6f820b11bc3 412 Pfam PF02515 CoA-transferase family III 12 380 2.7E-95 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 MIM_c20950 41ecc3445af603bc8064c6f820b11bc3 412 Gene3D G3DSA:3.30.1540.10 239 334 8.5E-103 T 12-10-2018 MIM_c20950 41ecc3445af603bc8064c6f820b11bc3 412 SUPERFAMILY SSF89796 8 404 6.93E-107 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c20950 41ecc3445af603bc8064c6f820b11bc3 412 Gene3D G3DSA:3.40.50.10540 11 398 8.5E-103 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c07280 5154794b2f6d134fafc4a1ea0e090111 317 Hamap MF_00737 Formimidoylglutamase [hutG]. 3 314 39.526 T 12-10-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 MIM_c07280 5154794b2f6d134fafc4a1ea0e090111 317 SUPERFAMILY SSF52768 8 313 1.8E-79 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily MIM_c07280 5154794b2f6d134fafc4a1ea0e090111 317 Gene3D G3DSA:3.40.800.10 2 316 3.3E-104 T 12-10-2018 MIM_c07280 5154794b2f6d134fafc4a1ea0e090111 317 ProSitePatterns PS01053 Arginase family signature. 243 264 - T 12-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 MIM_c07280 5154794b2f6d134fafc4a1ea0e090111 317 PIRSF PIRSF036979 32 315 2.9E-31 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 MIM_c07280 5154794b2f6d134fafc4a1ea0e090111 317 TIGRFAM TIGR01227 hutG: formimidoylglutamase 8 313 4.8E-92 T 12-10-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 MIM_c07280 5154794b2f6d134fafc4a1ea0e090111 317 Pfam PF00491 Arginase family 42 311 7.1E-56 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 MIM_c07280 5154794b2f6d134fafc4a1ea0e090111 317 PRINTS PR00116 Arginase signature 240 269 6.3E-5 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 MIM_c07280 5154794b2f6d134fafc4a1ea0e090111 317 PRINTS PR00116 Arginase signature 275 289 6.3E-5 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 MIM_c07280 5154794b2f6d134fafc4a1ea0e090111 317 PRINTS PR00116 Arginase signature 121 136 6.3E-5 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 MIM_c31340 f4c971df55ea819e76c6363edd174820 867 Gene3D G3DSA:3.30.499.20 10 360 3.4E-132 T 12-10-2018 MIM_c31340 f4c971df55ea819e76c6363edd174820 867 SUPERFAMILY SSF53732 23 586 1.26E-185 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 MIM_c31340 f4c971df55ea819e76c6363edd174820 867 Gene3D G3DSA:3.20.19.10 620 858 2.8E-84 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 MIM_c31340 f4c971df55ea819e76c6363edd174820 867 Pfam PF00694 Aconitase C-terminal domain 657 787 1.7E-30 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 MIM_c31340 f4c971df55ea819e76c6363edd174820 867 Gene3D G3DSA:1.10.1440.20 562 619 4.2E-8 T 12-10-2018 MIM_c31340 f4c971df55ea819e76c6363edd174820 867 PRINTS PR00415 Aconitase family signature 281 294 7.0E-28 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c31340 f4c971df55ea819e76c6363edd174820 867 PRINTS PR00415 Aconitase family signature 162 170 7.0E-28 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c31340 f4c971df55ea819e76c6363edd174820 867 PRINTS PR00415 Aconitase family signature 205 220 7.0E-28 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c31340 f4c971df55ea819e76c6363edd174820 867 PRINTS PR00415 Aconitase family signature 267 280 7.0E-28 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c31340 f4c971df55ea819e76c6363edd174820 867 PRINTS PR00415 Aconitase family signature 464 477 7.0E-28 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c31340 f4c971df55ea819e76c6363edd174820 867 PRINTS PR00415 Aconitase family signature 402 413 7.0E-28 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c31340 f4c971df55ea819e76c6363edd174820 867 PRINTS PR00415 Aconitase family signature 138 151 7.0E-28 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c31340 f4c971df55ea819e76c6363edd174820 867 PRINTS PR00415 Aconitase family signature 191 204 7.0E-28 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c31340 f4c971df55ea819e76c6363edd174820 867 PRINTS PR00415 Aconitase family signature 360 374 7.0E-28 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c31340 f4c971df55ea819e76c6363edd174820 867 Gene3D G3DSA:3.30.499.10 361 561 7.3E-76 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 MIM_c31340 f4c971df55ea819e76c6363edd174820 867 Pfam PF00330 Aconitase family (aconitate hydratase) 70 533 1.6E-145 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c31340 f4c971df55ea819e76c6363edd174820 867 TIGRFAM TIGR02333 2met_isocit_dHY: 2-methylisocitrate dehydratase, Fe/S-dependent 2 859 0.0 T 12-10-2018 IPR012708 2-methylisocitrate dehydratase AcnD, Fe/S-dependent GO:0019679 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 MIM_c31340 f4c971df55ea819e76c6363edd174820 867 SUPERFAMILY SSF52016 599 857 8.24E-68 T 12-10-2018 MIM_c17690 76462a22353769584d388c2050171ff4 271 Gene3D G3DSA:3.40.50.720 2 255 2.0E-61 T 12-10-2018 MIM_c17690 76462a22353769584d388c2050171ff4 271 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 248 1.1E-42 T 12-10-2018 MIM_c17690 76462a22353769584d388c2050171ff4 271 SUPERFAMILY SSF51735 2 249 3.64E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c17690 76462a22353769584d388c2050171ff4 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.9E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c17690 76462a22353769584d388c2050171ff4 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.9E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c17690 76462a22353769584d388c2050171ff4 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.9E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c17690 76462a22353769584d388c2050171ff4 271 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 194 1.8E-4 T 12-10-2018 MIM_c17690 76462a22353769584d388c2050171ff4 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.2E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c17690 76462a22353769584d388c2050171ff4 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.2E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c17690 76462a22353769584d388c2050171ff4 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 2.2E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c17690 76462a22353769584d388c2050171ff4 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.2E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c17690 76462a22353769584d388c2050171ff4 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.2E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c17690 76462a22353769584d388c2050171ff4 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.2E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c03310 3b57244fb7a118ca2164d9c7b5c941ed 392 Gene3D G3DSA:2.40.110.10 126 239 4.0E-46 T 12-10-2018 MIM_c03310 3b57244fb7a118ca2164d9c7b5c941ed 392 SUPERFAMILY SSF56645 6 247 1.7E-89 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c03310 3b57244fb7a118ca2164d9c7b5c941ed 392 PIRSF PIRSF016578 137 392 7.3E-9 T 12-10-2018 MIM_c03310 3b57244fb7a118ca2164d9c7b5c941ed 392 PIRSF PIRSF016578 12 111 0.0014 T 12-10-2018 MIM_c03310 3b57244fb7a118ca2164d9c7b5c941ed 392 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 222 1.4E-26 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MIM_c03310 3b57244fb7a118ca2164d9c7b5c941ed 392 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 346 365 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MIM_c03310 3b57244fb7a118ca2164d9c7b5c941ed 392 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 13 123 5.8E-39 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c03310 3b57244fb7a118ca2164d9c7b5c941ed 392 Gene3D G3DSA:1.20.140.10 240 392 8.4E-46 T 12-10-2018 MIM_c03310 3b57244fb7a118ca2164d9c7b5c941ed 392 Gene3D G3DSA:1.10.540.10 3 125 1.1E-49 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c03310 3b57244fb7a118ca2164d9c7b5c941ed 392 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 387 1.2E-37 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MIM_c03310 3b57244fb7a118ca2164d9c7b5c941ed 392 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 129 141 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MIM_c03310 3b57244fb7a118ca2164d9c7b5c941ed 392 SUPERFAMILY SSF47203 233 390 6.44E-45 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c35880 4daed56c6a7360c1ff9acd7422d38cf7 300 Gene3D G3DSA:3.40.190.10 91 291 2.6E-65 T 12-10-2018 MIM_c35880 4daed56c6a7360c1ff9acd7422d38cf7 300 SUPERFAMILY SSF53850 90 296 5.27E-47 T 12-10-2018 MIM_c35880 4daed56c6a7360c1ff9acd7422d38cf7 300 Gene3D G3DSA:1.10.10.10 3 89 1.8E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c35880 4daed56c6a7360c1ff9acd7422d38cf7 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 4.1E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c35880 4daed56c6a7360c1ff9acd7422d38cf7 300 Gene3D G3DSA:3.40.190.10 163 265 2.6E-65 T 12-10-2018 MIM_c35880 4daed56c6a7360c1ff9acd7422d38cf7 300 Pfam PF03466 LysR substrate binding domain 88 293 3.7E-46 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c35880 4daed56c6a7360c1ff9acd7422d38cf7 300 SUPERFAMILY SSF46785 4 85 6.58E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c12370 8ea19854834bf4bd5cf7fd285aca91ff 318 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 27 315 8.6E-11 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 MIM_c12370 8ea19854834bf4bd5cf7fd285aca91ff 318 Gene3D G3DSA:3.40.50.720 106 294 8.5E-93 T 12-10-2018 MIM_c12370 8ea19854834bf4bd5cf7fd285aca91ff 318 SUPERFAMILY SSF51735 109 292 4.4E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c12370 8ea19854834bf4bd5cf7fd285aca91ff 318 Gene3D G3DSA:3.40.50.720 5 305 8.5E-93 T 12-10-2018 MIM_c12370 8ea19854834bf4bd5cf7fd285aca91ff 318 SUPERFAMILY SSF52283 1 125 4.89E-18 T 12-10-2018 MIM_c12370 8ea19854834bf4bd5cf7fd285aca91ff 318 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 115 291 1.7E-47 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MIM_c27540 acf4841d932cc38d5e829f7531740aa5 275 Gene3D G3DSA:3.40.50.1820 1 262 1.2E-44 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c27540 acf4841d932cc38d5e829f7531740aa5 275 SUPERFAMILY SSF53474 2 258 9.56E-48 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c27540 acf4841d932cc38d5e829f7531740aa5 275 Pfam PF12697 Alpha/beta hydrolase family 22 250 1.4E-15 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c21300 1504ecb320cd1fc4d96f5d46522b16cb 393 Gene3D G3DSA:3.40.47.10 6 276 3.2E-149 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c21300 1504ecb320cd1fc4d96f5d46522b16cb 393 Gene3D G3DSA:3.40.47.10 127 389 3.2E-149 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c21300 1504ecb320cd1fc4d96f5d46522b16cb 393 Pfam PF02803 Thiolase, C-terminal domain 271 392 1.8E-43 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 MIM_c21300 1504ecb320cd1fc4d96f5d46522b16cb 393 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 12-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 MIM_c21300 1504ecb320cd1fc4d96f5d46522b16cb 393 PIRSF PIRSF000429 1 393 2.8E-126 T 12-10-2018 IPR002155 Thiolase GO:0016747 MIM_c21300 1504ecb320cd1fc4d96f5d46522b16cb 393 SUPERFAMILY SSF53901 3 269 5.39E-84 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c21300 1504ecb320cd1fc4d96f5d46522b16cb 393 SUPERFAMILY SSF53901 271 392 5.76E-42 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c21300 1504ecb320cd1fc4d96f5d46522b16cb 393 Pfam PF00108 Thiolase, N-terminal domain 4 261 3.4E-91 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 MIM_c21300 1504ecb320cd1fc4d96f5d46522b16cb 393 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 MIM_c21300 1504ecb320cd1fc4d96f5d46522b16cb 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 391 1.3E-139 T 12-10-2018 IPR002155 Thiolase GO:0016747 MIM_c09350 26d9d64f3f61e909850fbf5cb2e450ab 240 SUPERFAMILY SSF50475 61 230 1.03E-40 T 12-10-2018 MIM_c09350 26d9d64f3f61e909850fbf5cb2e450ab 240 SMART SM00903 72 224 1.5E-12 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MIM_c09350 26d9d64f3f61e909850fbf5cb2e450ab 240 Pfam PF01613 Flavin reductase like domain 76 217 3.4E-22 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MIM_c09350 26d9d64f3f61e909850fbf5cb2e450ab 240 Gene3D G3DSA:2.30.110.10 61 234 9.9E-47 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MIM_c16120 6383089a0b7673da7135ae6feb2e030f 470 Gene3D G3DSA:3.40.1440.10 198 294 1.5E-21 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 MIM_c16120 6383089a0b7673da7135ae6feb2e030f 470 SMART SM00465 209 290 8.8E-9 T 12-10-2018 IPR000305 GIY-YIG endonuclease MIM_c16120 6383089a0b7673da7135ae6feb2e030f 470 SUPERFAMILY SSF53098 10 184 4.56E-52 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily MIM_c16120 6383089a0b7673da7135ae6feb2e030f 470 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 16 176 5.3E-25 T 12-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MIM_c16120 6383089a0b7673da7135ae6feb2e030f 470 SUPERFAMILY SSF82771 208 289 1.02E-12 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 MIM_c16120 6383089a0b7673da7135ae6feb2e030f 470 Pfam PF00929 Exonuclease 17 166 1.2E-31 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MIM_c16120 6383089a0b7673da7135ae6feb2e030f 470 Gene3D G3DSA:3.30.420.10 10 182 1.9E-47 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MIM_c16120 6383089a0b7673da7135ae6feb2e030f 470 SMART SM00479 14 178 3.1E-43 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MIM_c01840 91f24402d57fa394d01f2a952e7b7b9f 376 Pfam PF08021 Siderophore-interacting FAD-binding domain 113 227 1.4E-29 T 12-10-2018 IPR013113 FAD-binding 9, siderophore-interacting MIM_c01840 91f24402d57fa394d01f2a952e7b7b9f 376 Gene3D G3DSA:3.30.310.50 4 98 1.7E-5 T 12-10-2018 MIM_c01840 91f24402d57fa394d01f2a952e7b7b9f 376 Pfam PF09981 Uncharacterized protein conserved in bacteria (DUF2218) 10 96 5.5E-9 T 12-10-2018 IPR014543 Uncharacterised conserved protein UCP028291 MIM_c01840 91f24402d57fa394d01f2a952e7b7b9f 376 SUPERFAMILY SSF63380 101 227 5.95E-8 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MIM_c01840 91f24402d57fa394d01f2a952e7b7b9f 376 Gene3D G3DSA:2.40.30.10 99 227 1.2E-34 T 12-10-2018 MIM_c01840 91f24402d57fa394d01f2a952e7b7b9f 376 Gene3D G3DSA:3.40.50.80 228 373 3.5E-42 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MIM_c01840 91f24402d57fa394d01f2a952e7b7b9f 376 Pfam PF04954 Siderophore-interacting protein 233 352 2.5E-32 T 12-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain MIM_c25380 6aeb246ff09d381a6c16b30c0e1282f5 358 SUPERFAMILY SSF53774 27 356 1.7E-89 T 12-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 MIM_c25380 6aeb246ff09d381a6c16b30c0e1282f5 358 PIRSF PIRSF500176 27 357 3.1E-75 T 12-10-2018 MIM_c25380 6aeb246ff09d381a6c16b30c0e1282f5 358 SMART SM00870 30 352 1.4E-103 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c25380 6aeb246ff09d381a6c16b30c0e1282f5 358 Gene3D G3DSA:3.40.50.1170 26 246 5.1E-70 T 12-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 MIM_c25380 6aeb246ff09d381a6c16b30c0e1282f5 358 PRINTS PR00139 Asparaginase/glutaminase family signature 294 312 4.2E-16 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c25380 6aeb246ff09d381a6c16b30c0e1282f5 358 PRINTS PR00139 Asparaginase/glutaminase family signature 31 42 4.2E-16 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c25380 6aeb246ff09d381a6c16b30c0e1282f5 358 PRINTS PR00139 Asparaginase/glutaminase family signature 115 133 4.2E-16 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c25380 6aeb246ff09d381a6c16b30c0e1282f5 358 TIGRFAM TIGR00520 asnASE_II: L-asparaginase, type II 26 358 1.3E-95 T 12-10-2018 IPR004550 L-asparaginase, type II GO:0004067|GO:0006528 MIM_c25380 6aeb246ff09d381a6c16b30c0e1282f5 358 Pfam PF00710 Asparaginase, N-terminal 30 227 1.1E-53 T 12-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 MIM_c25380 6aeb246ff09d381a6c16b30c0e1282f5 358 PIRSF PIRSF001220 25 358 3.9E-79 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c25380 6aeb246ff09d381a6c16b30c0e1282f5 358 Gene3D G3DSA:3.40.50.40 247 358 4.7E-35 T 12-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 MIM_c05360 b1b92da3ee2a647011d80170c33a5c7b 189 Gene3D G3DSA:3.40.50.880 1 188 4.8E-66 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c05360 b1b92da3ee2a647011d80170c33a5c7b 189 SUPERFAMILY SSF52317 1 187 5.87E-57 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c05360 b1b92da3ee2a647011d80170c33a5c7b 189 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 5.6E-5 T 12-10-2018 MIM_c05360 b1b92da3ee2a647011d80170c33a5c7b 189 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 5.6E-5 T 12-10-2018 MIM_c05360 b1b92da3ee2a647011d80170c33a5c7b 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 1.1E-12 T 12-10-2018 MIM_c05360 b1b92da3ee2a647011d80170c33a5c7b 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 1.1E-12 T 12-10-2018 MIM_c05360 b1b92da3ee2a647011d80170c33a5c7b 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.1E-12 T 12-10-2018 MIM_c05360 b1b92da3ee2a647011d80170c33a5c7b 189 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 186 1.4E-79 T 12-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MIM_c05360 b1b92da3ee2a647011d80170c33a5c7b 189 Pfam PF00117 Glutamine amidotransferase class-I 4 185 9.9E-56 T 12-10-2018 IPR017926 Glutamine amidotransferase MIM_c05360 b1b92da3ee2a647011d80170c33a5c7b 189 PRINTS PR00097 Anthranilate synthase component II signature 99 107 2.0E-34 T 12-10-2018 MIM_c05360 b1b92da3ee2a647011d80170c33a5c7b 189 PRINTS PR00097 Anthranilate synthase component II signature 74 85 2.0E-34 T 12-10-2018 MIM_c05360 b1b92da3ee2a647011d80170c33a5c7b 189 PRINTS PR00097 Anthranilate synthase component II signature 119 131 2.0E-34 T 12-10-2018 MIM_c05360 b1b92da3ee2a647011d80170c33a5c7b 189 PRINTS PR00097 Anthranilate synthase component II signature 164 177 2.0E-34 T 12-10-2018 MIM_c05360 b1b92da3ee2a647011d80170c33a5c7b 189 PRINTS PR00097 Anthranilate synthase component II signature 47 56 2.0E-34 T 12-10-2018 MIM_c05360 b1b92da3ee2a647011d80170c33a5c7b 189 PRINTS PR00097 Anthranilate synthase component II signature 2 16 2.0E-34 T 12-10-2018 MIM_c21500 1973d95905314b11e7d55a2b17a46b73 337 PIRSF PIRSF028757 32 333 3.8E-67 T 12-10-2018 IPR003507 Peptidase family S66 MIM_c21500 1973d95905314b11e7d55a2b17a46b73 337 Gene3D G3DSA:3.50.30.60 189 325 7.4E-42 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily MIM_c21500 1973d95905314b11e7d55a2b17a46b73 337 Pfam PF02016 LD-carboxypeptidase 43 317 3.9E-69 T 12-10-2018 IPR003507 Peptidase family S66 MIM_c21500 1973d95905314b11e7d55a2b17a46b73 337 SUPERFAMILY SSF52317 42 189 2.29E-33 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c21500 1973d95905314b11e7d55a2b17a46b73 337 Gene3D G3DSA:3.40.50.10740 32 185 1.9E-35 T 12-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal MIM_c21500 1973d95905314b11e7d55a2b17a46b73 337 SUPERFAMILY SSF141986 170 321 3.66E-40 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily MIM_c38890 51929ac34bcd795736bca78474b7ebd5 692 Pfam PF13899 Thioredoxin-like 584 663 1.7E-10 T 12-10-2018 MIM_c38890 51929ac34bcd795736bca78474b7ebd5 692 Gene3D G3DSA:3.40.30.10 568 691 1.1E-30 T 12-10-2018 MIM_c38890 51929ac34bcd795736bca78474b7ebd5 692 SUPERFAMILY SSF74863 30 152 2.75E-32 T 12-10-2018 IPR036929 Thiol:disulfide interchange protein DsbD, N-terminal domain superfamily MIM_c38890 51929ac34bcd795736bca78474b7ebd5 692 Hamap MF_00399 Thiol:disulfide interchange protein DsbD [dsbD]. 11 691 32.773 T 12-10-2018 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 MIM_c38890 51929ac34bcd795736bca78474b7ebd5 692 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 276 486 4.2E-21 T 12-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 MIM_c38890 51929ac34bcd795736bca78474b7ebd5 692 SUPERFAMILY SSF52833 583 687 9.67E-23 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c38890 51929ac34bcd795736bca78474b7ebd5 692 Gene3D G3DSA:2.60.40.1250 28 156 1.0E-36 T 12-10-2018 IPR036929 Thiol:disulfide interchange protein DsbD, N-terminal domain superfamily MIM_c38890 51929ac34bcd795736bca78474b7ebd5 692 Pfam PF11412 Disulphide bond corrector protein DsbC 32 150 5.7E-29 T 12-10-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain MIM_c13090 24c3d3d970400409ebc79d5fe893a3a1 185 ProSitePatterns PS01275 Elongation factor P signature. 149 168 - T 12-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site MIM_c13090 24c3d3d970400409ebc79d5fe893a3a1 185 SUPERFAMILY SSF50249 65 126 1.16E-16 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c13090 24c3d3d970400409ebc79d5fe893a3a1 185 TIGRFAM TIGR00038 efp: translation elongation factor P 3 184 6.8E-64 T 12-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 MIM_c13090 24c3d3d970400409ebc79d5fe893a3a1 185 Hamap MF_00141 Elongation factor P [efp]. 1 184 46.374 T 12-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 MIM_c13090 24c3d3d970400409ebc79d5fe893a3a1 185 Gene3D G3DSA:2.40.50.140 64 126 2.8E-23 T 12-10-2018 MIM_c13090 24c3d3d970400409ebc79d5fe893a3a1 185 Gene3D G3DSA:2.30.30.30 1 62 1.1E-17 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 MIM_c13090 24c3d3d970400409ebc79d5fe893a3a1 185 Pfam PF09285 Elongation factor P, C-terminal 128 183 1.4E-23 T 12-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 MIM_c13090 24c3d3d970400409ebc79d5fe893a3a1 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 6.4E-17 T 12-10-2018 IPR013185 Translation elongation factor, KOW-like MIM_c13090 24c3d3d970400409ebc79d5fe893a3a1 185 SMART SM01185 67 120 3.6E-22 T 12-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 MIM_c13090 24c3d3d970400409ebc79d5fe893a3a1 185 SUPERFAMILY SSF50249 128 184 1.4E-16 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c13090 24c3d3d970400409ebc79d5fe893a3a1 185 PIRSF PIRSF005901 1 185 3.5E-55 T 12-10-2018 IPR020599 Translation elongation factor P/YeiP MIM_c13090 24c3d3d970400409ebc79d5fe893a3a1 185 SUPERFAMILY SSF50104 1 63 3.06E-15 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily MIM_c13090 24c3d3d970400409ebc79d5fe893a3a1 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 120 6.2E-19 T 12-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 MIM_c13090 24c3d3d970400409ebc79d5fe893a3a1 185 SMART SM00841 128 183 5.0E-27 T 12-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 MIM_c13090 24c3d3d970400409ebc79d5fe893a3a1 185 Gene3D G3DSA:2.40.50.140 127 185 2.5E-27 T 12-10-2018 MIM_c17460 7a157a2184acb3fd7c95412621e05562 477 Gene3D G3DSA:3.30.70.2190 227 348 1.1E-33 T 12-10-2018 MIM_c17460 7a157a2184acb3fd7c95412621e05562 477 SUPERFAMILY SSF56176 12 227 1.2E-76 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MIM_c17460 7a157a2184acb3fd7c95412621e05562 477 Pfam PF01565 FAD binding domain 51 187 6.9E-35 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MIM_c17460 7a157a2184acb3fd7c95412621e05562 477 Gene3D G3DSA:1.10.45.10 437 477 2.0E-15 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 MIM_c17460 7a157a2184acb3fd7c95412621e05562 477 Gene3D G3DSA:3.30.70.2740 350 436 1.8E-27 T 12-10-2018 MIM_c17460 7a157a2184acb3fd7c95412621e05562 477 Pfam PF02913 FAD linked oxidases, C-terminal domain 227 476 5.1E-51 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 MIM_c17460 7a157a2184acb3fd7c95412621e05562 477 SUPERFAMILY SSF55103 230 477 8.83E-54 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MIM_c17460 7a157a2184acb3fd7c95412621e05562 477 Gene3D G3DSA:3.30.465.10 105 225 4.1E-45 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MIM_c17460 7a157a2184acb3fd7c95412621e05562 477 Gene3D G3DSA:3.30.43.10 7 103 1.1E-25 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 MIM_c08080 2987b7516cc7af6c640a766c92fbda9f 461 ProSitePatterns PS00571 Amidases signature. 155 186 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 MIM_c08080 2987b7516cc7af6c640a766c92fbda9f 461 Pfam PF01425 Amidase 26 441 3.5E-97 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MIM_c08080 2987b7516cc7af6c640a766c92fbda9f 461 SUPERFAMILY SSF75304 3 458 1.13E-122 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MIM_c08080 2987b7516cc7af6c640a766c92fbda9f 461 Gene3D G3DSA:3.90.1300.10 7 451 1.8E-125 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MIM_c32250 e6097bdbffa4aa32bb9cf4eec2f3480d 172 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 11 94 0.002 T 12-10-2018 MIM_c32250 e6097bdbffa4aa32bb9cf4eec2f3480d 172 SUPERFAMILY SSF52374 1 156 7.51E-43 T 12-10-2018 MIM_c32250 e6097bdbffa4aa32bb9cf4eec2f3480d 172 Gene3D G3DSA:3.40.50.620 1 166 4.1E-53 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c32250 e6097bdbffa4aa32bb9cf4eec2f3480d 172 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 158 34.399 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MIM_c32250 e6097bdbffa4aa32bb9cf4eec2f3480d 172 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 57 9.0E-14 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MIM_c32250 e6097bdbffa4aa32bb9cf4eec2f3480d 172 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 156 9.1E-55 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MIM_c32250 e6097bdbffa4aa32bb9cf4eec2f3480d 172 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 5.9E-46 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MIM_c32250 e6097bdbffa4aa32bb9cf4eec2f3480d 172 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 5.9E-46 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MIM_c32250 e6097bdbffa4aa32bb9cf4eec2f3480d 172 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 112 134 5.9E-46 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MIM_c32250 e6097bdbffa4aa32bb9cf4eec2f3480d 172 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 5.9E-46 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MIM_c32250 e6097bdbffa4aa32bb9cf4eec2f3480d 172 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 5.9E-46 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MIM_c32250 e6097bdbffa4aa32bb9cf4eec2f3480d 172 Pfam PF01467 Cytidylyltransferase-like 5 133 9.2E-18 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MIM_c28760 341fa66391fa9d4b06f3474f75403859 356 SUPERFAMILY SSF141571 162 325 5.69E-33 T 12-10-2018 MIM_c28760 341fa66391fa9d4b06f3474f75403859 356 SUPERFAMILY SSF141571 20 183 5.76E-30 T 12-10-2018 MIM_c28760 341fa66391fa9d4b06f3474f75403859 356 Gene3D G3DSA:2.160.20.80 182 333 4.2E-24 T 12-10-2018 MIM_c28760 341fa66391fa9d4b06f3474f75403859 356 Pfam PF13599 Pentapeptide repeats (9 copies) 28 99 3.0E-12 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c28760 341fa66391fa9d4b06f3474f75403859 356 Pfam PF13599 Pentapeptide repeats (9 copies) 194 260 4.1E-11 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c28760 341fa66391fa9d4b06f3474f75403859 356 Gene3D G3DSA:2.160.20.100 12 181 4.1E-30 T 12-10-2018 MIM_c28760 341fa66391fa9d4b06f3474f75403859 356 Pfam PF00805 Pentapeptide repeats (8 copies) 278 317 3.6E-9 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c28760 341fa66391fa9d4b06f3474f75403859 356 Pfam PF00805 Pentapeptide repeats (8 copies) 122 156 1.6E-4 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c39400 ffaba51d83799ccf8fc0eb41a1f185e3 209 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 6 204 2.9E-72 T 12-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MIM_c39400 ffaba51d83799ccf8fc0eb41a1f185e3 209 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 35 44 - T 12-10-2018 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MIM_c39400 ffaba51d83799ccf8fc0eb41a1f185e3 209 Pfam PF01081 KDPG and KHG aldolase 5 197 3.4E-68 T 12-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MIM_c39400 ffaba51d83799ccf8fc0eb41a1f185e3 209 SUPERFAMILY SSF51569 3 203 4.4E-65 T 12-10-2018 MIM_c39400 ffaba51d83799ccf8fc0eb41a1f185e3 209 Gene3D G3DSA:3.20.20.70 2 208 9.6E-72 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c05220 659c6f2402b58444e69b456fda945d71 207 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 9 195 4.4E-35 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase MIM_c05220 659c6f2402b58444e69b456fda945d71 207 Gene3D G3DSA:3.40.50.10420 7 203 2.4E-38 T 12-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily MIM_c05220 659c6f2402b58444e69b456fda945d71 207 PIRSF PIRSF006806 3 197 1.2E-28 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase MIM_c05220 659c6f2402b58444e69b456fda945d71 207 SUPERFAMILY SSF100950 8 201 1.53E-40 T 12-10-2018 IPR037171 NagB/RpiA transferase-like MIM_c05220 659c6f2402b58444e69b456fda945d71 207 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 9 195 1.2E-24 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase MIM_c03790 f0af931d9aaa4c4d99dbc718c41531e4 341 Pfam PF00005 ABC transporter 20 165 1.5E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c03790 f0af931d9aaa4c4d99dbc718c41531e4 341 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c03790 f0af931d9aaa4c4d99dbc718c41531e4 341 SUPERFAMILY SSF50331 274 334 2.78E-6 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MIM_c03790 f0af931d9aaa4c4d99dbc718c41531e4 341 Gene3D G3DSA:3.40.50.300 1 242 7.2E-73 T 12-10-2018 MIM_c03790 f0af931d9aaa4c4d99dbc718c41531e4 341 SMART SM00382 28 215 2.0E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c03790 f0af931d9aaa4c4d99dbc718c41531e4 341 SUPERFAMILY SSF52540 4 241 4.19E-80 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c03790 f0af931d9aaa4c4d99dbc718c41531e4 341 Pfam PF08402 TOBE domain 276 336 5.1E-8 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 MIM_c03230 d397eef54eead261a0ff1b35b9d4852a 314 SUPERFAMILY SSF52374 26 283 1.16E-76 T 12-10-2018 MIM_c03230 d397eef54eead261a0ff1b35b9d4852a 314 Gene3D G3DSA:3.40.50.620 101 250 1.6E-91 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c03230 d397eef54eead261a0ff1b35b9d4852a 314 PRINTS PR00987 Glutamyl-tRNA synthetase signature 29 41 1.2E-10 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MIM_c03230 d397eef54eead261a0ff1b35b9d4852a 314 PRINTS PR00987 Glutamyl-tRNA synthetase signature 218 226 1.2E-10 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MIM_c03230 d397eef54eead261a0ff1b35b9d4852a 314 PRINTS PR00987 Glutamyl-tRNA synthetase signature 202 212 1.2E-10 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MIM_c03230 d397eef54eead261a0ff1b35b9d4852a 314 PRINTS PR00987 Glutamyl-tRNA synthetase signature 58 71 1.2E-10 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MIM_c03230 d397eef54eead261a0ff1b35b9d4852a 314 Hamap MF_01428 Glutamyl-Q tRNA(Asp) synthetase [gluQ]. 26 314 39.232 T 12-10-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0004812|GO:0006400 MIM_c03230 d397eef54eead261a0ff1b35b9d4852a 314 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 26 291 7.2E-109 T 12-10-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0004812|GO:0006400 MIM_c03230 d397eef54eead261a0ff1b35b9d4852a 314 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 29 272 7.9E-43 T 12-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 MIM_c03230 d397eef54eead261a0ff1b35b9d4852a 314 Gene3D G3DSA:3.40.50.620 28 292 1.6E-91 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c36770 b38e976d198075a3bb85a78845357895 309 SUPERFAMILY SSF89562 21 183 2.62E-46 T 12-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily MIM_c36770 b38e976d198075a3bb85a78845357895 309 Gene3D G3DSA:3.50.30.100 2 194 2.3E-55 T 12-10-2018 MIM_c36770 b38e976d198075a3bb85a78845357895 309 Pfam PF03737 Aldolase/RraA 27 172 1.2E-43 T 12-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MIM_c14650 341f6df876a00d243c15cf55e64779c6 439 SMART SM00981 116 214 3.4E-17 T 12-10-2018 IPR004114 THUMP domain GO:0003723 MIM_c14650 341f6df876a00d243c15cf55e64779c6 439 Gene3D G3DSA:3.30.2130.30 65 311 1.3E-129 T 12-10-2018 MIM_c14650 341f6df876a00d243c15cf55e64779c6 439 Gene3D G3DSA:3.40.50.150 229 424 1.3E-129 T 12-10-2018 MIM_c14650 341f6df876a00d243c15cf55e64779c6 439 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 360 366 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MIM_c14650 341f6df876a00d243c15cf55e64779c6 439 SUPERFAMILY SSF53335 209 427 2.25E-42 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c14650 341f6df876a00d243c15cf55e64779c6 439 Pfam PF02926 THUMP domain 96 212 9.6E-9 T 12-10-2018 IPR004114 THUMP domain GO:0003723 MIM_c14650 341f6df876a00d243c15cf55e64779c6 439 Pfam PF01170 Putative RNA methylase family UPF0020 222 426 1.0E-45 T 12-10-2018 IPR000241 Putative RNA methylase domain MIM_c14650 341f6df876a00d243c15cf55e64779c6 439 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 255 266 - T 12-10-2018 IPR000241 Putative RNA methylase domain MIM_c21140 25e5eccb3b7f5c96abc0172adc21e045 435 SUPERFAMILY SSF88659 130 185 4.14E-7 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MIM_c21140 25e5eccb3b7f5c96abc0172adc21e045 435 Pfam PF04542 Sigma-70 region 2 28 87 1.9E-4 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MIM_c21140 25e5eccb3b7f5c96abc0172adc21e045 435 Pfam PF08281 Sigma-70, region 4 135 181 5.7E-6 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MIM_c21140 25e5eccb3b7f5c96abc0172adc21e045 435 Pfam PF10099 Anti-sigma-K factor rskA 249 430 3.2E-17 T 12-10-2018 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 MIM_c21140 25e5eccb3b7f5c96abc0172adc21e045 435 SUPERFAMILY SSF88946 6 91 1.02E-10 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MIM_c21140 25e5eccb3b7f5c96abc0172adc21e045 435 Gene3D G3DSA:1.10.1740.10 9 92 5.5E-16 T 12-10-2018 MIM_c21140 25e5eccb3b7f5c96abc0172adc21e045 435 Gene3D G3DSA:1.10.10.10 93 186 5.2E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c27840 a5d695f1e1bb4be87a73b1b88f8fb994 417 Gene3D G3DSA:3.40.1090.10 12 130 2.4E-17 T 12-10-2018 MIM_c27840 a5d695f1e1bb4be87a73b1b88f8fb994 417 SUPERFAMILY SSF52151 22 277 4.71E-42 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase MIM_c27840 a5d695f1e1bb4be87a73b1b88f8fb994 417 Pfam PF01734 Patatin-like phospholipase 26 250 5.7E-17 T 12-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 MIM_c15520 dc962ac42793aeb6fdd236258109bbaa 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 284 1.1E-25 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c15520 dc962ac42793aeb6fdd236258109bbaa 288 Gene3D G3DSA:1.10.3720.10 15 285 5.6E-63 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c15520 dc962ac42793aeb6fdd236258109bbaa 288 SUPERFAMILY SSF161098 17 278 1.59E-52 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c15520 dc962ac42793aeb6fdd236258109bbaa 288 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 10 283 9.7E-114 T 12-10-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 MIM_c15520 dc962ac42793aeb6fdd236258109bbaa 288 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 6 278 1.3E-88 T 12-10-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 MIM_c24340 556ae04eb8015b45ad122a470ae409ee 247 Gene3D G3DSA:1.10.10.10 139 246 4.7E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c24340 556ae04eb8015b45ad122a470ae409ee 247 Pfam PF00486 Transcriptional regulatory protein, C terminal 167 241 6.2E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MIM_c24340 556ae04eb8015b45ad122a470ae409ee 247 SUPERFAMILY SSF52172 5 134 4.55E-45 T 12-10-2018 IPR011006 CheY-like superfamily MIM_c24340 556ae04eb8015b45ad122a470ae409ee 247 Pfam PF00072 Response regulator receiver domain 15 125 1.1E-33 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c24340 556ae04eb8015b45ad122a470ae409ee 247 SMART SM00862 165 241 4.2E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MIM_c24340 556ae04eb8015b45ad122a470ae409ee 247 Gene3D G3DSA:3.40.50.2300 1 138 1.8E-41 T 12-10-2018 MIM_c24340 556ae04eb8015b45ad122a470ae409ee 247 SMART SM00448 13 124 9.6E-48 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c24340 556ae04eb8015b45ad122a470ae409ee 247 SUPERFAMILY SSF46894 141 243 7.65E-27 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MIM_c09620 1f6710217e295f81b4e33e62265d24c1 425 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 244 275 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 MIM_c09620 1f6710217e295f81b4e33e62265d24c1 425 SUPERFAMILY SSF54826 3 138 6.19E-38 T 12-10-2018 MIM_c09620 1f6710217e295f81b4e33e62265d24c1 425 SUPERFAMILY SSF51604 183 423 8.25E-69 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MIM_c09620 1f6710217e295f81b4e33e62265d24c1 425 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 34 135 4.5E-6 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain MIM_c09620 1f6710217e295f81b4e33e62265d24c1 425 SMART SM00922 198 294 8.2E-25 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MIM_c09620 1f6710217e295f81b4e33e62265d24c1 425 Gene3D G3DSA:3.30.390.10 1 130 1.8E-57 T 12-10-2018 IPR029017 Enolase-like, N-terminal MIM_c09620 1f6710217e295f81b4e33e62265d24c1 425 Gene3D G3DSA:3.20.20.120 131 425 2.0E-110 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MIM_c09620 1f6710217e295f81b4e33e62265d24c1 425 Pfam PF13378 Enolase C-terminal domain-like 201 416 4.9E-57 T 12-10-2018 IPR029065 Enolase C-terminal domain-like MIM_c35820 ad8407b8f7cd223bf98aaa9db1005b69 450 TIGRFAM TIGR00895 2A0115: MFS transporter, aromatic acid:H+ symporter (AAHS) family 14 414 2.6E-155 T 12-10-2018 IPR004746 Major facilitator superfamily, aromatic acid:H+ symporter family GO:0016021|GO:0022857|GO:0055085 MIM_c35820 ad8407b8f7cd223bf98aaa9db1005b69 450 ProSitePatterns PS00216 Sugar transport proteins signature 1. 85 101 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MIM_c35820 ad8407b8f7cd223bf98aaa9db1005b69 450 Gene3D G3DSA:1.20.1250.20 25 301 3.4E-59 T 12-10-2018 MIM_c35820 ad8407b8f7cd223bf98aaa9db1005b69 450 Gene3D G3DSA:1.20.1250.20 302 442 7.1E-11 T 12-10-2018 MIM_c35820 ad8407b8f7cd223bf98aaa9db1005b69 450 Pfam PF07690 Major Facilitator Superfamily 36 407 1.7E-45 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c35820 ad8407b8f7cd223bf98aaa9db1005b69 450 SUPERFAMILY SSF103473 17 440 5.23E-80 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c35820 ad8407b8f7cd223bf98aaa9db1005b69 450 ProSitePatterns PS00217 Sugar transport proteins signature 2. 127 152 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MIM_c39250 04ce85a51a345b3c59ddbb2ea06d0d6e 248 SUPERFAMILY SSF51735 7 248 3.44E-74 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c39250 04ce85a51a345b3c59ddbb2ea06d0d6e 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 5.9E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c39250 04ce85a51a345b3c59ddbb2ea06d0d6e 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 5.9E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c39250 04ce85a51a345b3c59ddbb2ea06d0d6e 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 5.9E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c39250 04ce85a51a345b3c59ddbb2ea06d0d6e 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 132 160 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c39250 04ce85a51a345b3c59ddbb2ea06d0d6e 248 Gene3D G3DSA:3.40.50.720 3 248 5.9E-75 T 12-10-2018 MIM_c39250 04ce85a51a345b3c59ddbb2ea06d0d6e 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 1.7E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c39250 04ce85a51a345b3c59ddbb2ea06d0d6e 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 1.7E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c39250 04ce85a51a345b3c59ddbb2ea06d0d6e 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 1.7E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c39250 04ce85a51a345b3c59ddbb2ea06d0d6e 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.7E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c39250 04ce85a51a345b3c59ddbb2ea06d0d6e 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.7E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c39250 04ce85a51a345b3c59ddbb2ea06d0d6e 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 1.7E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c39250 04ce85a51a345b3c59ddbb2ea06d0d6e 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 247 1.2E-60 T 12-10-2018 MIM_c40540 3f915ec38f0b6d52e59421db6033c4cd 309 Gene3D G3DSA:3.40.190.10 164 264 1.1E-63 T 12-10-2018 MIM_c40540 3f915ec38f0b6d52e59421db6033c4cd 309 Pfam PF03466 LysR substrate binding domain 90 293 3.1E-46 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c40540 3f915ec38f0b6d52e59421db6033c4cd 309 SUPERFAMILY SSF46785 2 113 1.86E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c40540 3f915ec38f0b6d52e59421db6033c4cd 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 1.1E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c40540 3f915ec38f0b6d52e59421db6033c4cd 309 Gene3D G3DSA:1.10.10.10 3 92 9.9E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c40540 3f915ec38f0b6d52e59421db6033c4cd 309 Gene3D G3DSA:3.40.190.10 93 291 1.1E-63 T 12-10-2018 MIM_c40540 3f915ec38f0b6d52e59421db6033c4cd 309 SUPERFAMILY SSF53850 88 296 2.95E-47 T 12-10-2018 MIM_c10440 ce15d25f4d95241a267ea8b1074ee810 883 SUPERFAMILY SSF103088 781 881 2.62E-29 T 12-10-2018 IPR036737 OmpA-like domain superfamily MIM_c10440 ce15d25f4d95241a267ea8b1074ee810 883 Pfam PF00691 OmpA family 783 876 2.6E-22 T 12-10-2018 IPR006665 OmpA-like domain MIM_c10440 ce15d25f4d95241a267ea8b1074ee810 883 Gene3D G3DSA:3.40.1520.20 648 752 9.0E-10 T 12-10-2018 MIM_c10440 ce15d25f4d95241a267ea8b1074ee810 883 PRINTS PR01021 OMPA domain signature 812 827 2.0E-9 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MIM_c10440 ce15d25f4d95241a267ea8b1074ee810 883 PRINTS PR01021 OMPA domain signature 827 843 2.0E-9 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MIM_c10440 ce15d25f4d95241a267ea8b1074ee810 883 PRINTS PR01021 OMPA domain signature 783 805 2.0E-9 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MIM_c10440 ce15d25f4d95241a267ea8b1074ee810 883 Pfam PF06078 Bacterial protein of unknown function (DUF937) 9 142 1.6E-15 T 12-10-2018 IPR009282 Protein of unknown function DUF937 MIM_c10440 ce15d25f4d95241a267ea8b1074ee810 883 Pfam PF04972 BON domain 648 692 5.2E-4 T 12-10-2018 IPR007055 BON domain MIM_c10440 ce15d25f4d95241a267ea8b1074ee810 883 Pfam PF04972 BON domain 712 761 0.002 T 12-10-2018 IPR007055 BON domain MIM_c10440 ce15d25f4d95241a267ea8b1074ee810 883 Gene3D G3DSA:3.30.1330.60 753 883 5.7E-32 T 12-10-2018 IPR036737 OmpA-like domain superfamily MIM_c02800 1f5199a9b720d5326701f57bb5c4fd59 544 Gene3D G3DSA:3.40.190.10 54 530 1.1E-160 T 12-10-2018 MIM_c02800 1f5199a9b720d5326701f57bb5c4fd59 544 Gene3D G3DSA:3.90.76.10 75 197 1.1E-160 T 12-10-2018 MIM_c02800 1f5199a9b720d5326701f57bb5c4fd59 544 SUPERFAMILY SSF53850 41 539 9.67E-132 T 12-10-2018 MIM_c02800 1f5199a9b720d5326701f57bb5c4fd59 544 PIRSF PIRSF002741 11 543 1.3E-108 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MIM_c02800 1f5199a9b720d5326701f57bb5c4fd59 544 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 88 467 6.1E-84 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain MIM_c02800 1f5199a9b720d5326701f57bb5c4fd59 544 Gene3D G3DSA:3.10.105.10 299 517 1.1E-160 T 12-10-2018 MIM_c30440 13a598ee8f6629748ea975b130a7976f 220 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 109 4.3E-29 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c30440 13a598ee8f6629748ea975b130a7976f 220 Gene3D G3DSA:1.10.3720.10 1 217 5.4E-43 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c30440 13a598ee8f6629748ea975b130a7976f 220 SUPERFAMILY SSF161098 12 200 5.36E-36 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c30440 13a598ee8f6629748ea975b130a7976f 220 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 48 213 1.9E-13 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c27130 b8b4a0cb4d772b26e32853c9509e9eac 275 Gene3D G3DSA:3.40.190.10 123 215 3.9E-62 T 12-10-2018 MIM_c27130 b8b4a0cb4d772b26e32853c9509e9eac 275 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 256 1.5E-52 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c27130 b8b4a0cb4d772b26e32853c9509e9eac 275 Gene3D G3DSA:3.40.190.10 25 256 3.9E-62 T 12-10-2018 MIM_c27130 b8b4a0cb4d772b26e32853c9509e9eac 275 SMART SM00062 35 258 1.1E-58 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c27130 b8b4a0cb4d772b26e32853c9509e9eac 275 SUPERFAMILY SSF53850 5 257 1.01E-59 T 12-10-2018 MIM_c27130 b8b4a0cb4d772b26e32853c9509e9eac 275 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 59 72 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site MIM_c32530 c3d570e2f045a01592ab6fdeefd2d090 410 Pfam PF00534 Glycosyl transferases group 1 216 371 4.1E-31 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 MIM_c32530 c3d570e2f045a01592ab6fdeefd2d090 410 Pfam PF13579 Glycosyl transferase 4-like domain 13 171 1.6E-14 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MIM_c32530 c3d570e2f045a01592ab6fdeefd2d090 410 SUPERFAMILY SSF53756 2 392 2.45E-69 T 12-10-2018 MIM_c32530 c3d570e2f045a01592ab6fdeefd2d090 410 Gene3D G3DSA:3.40.50.2000 216 379 8.3E-41 T 12-10-2018 MIM_c32530 c3d570e2f045a01592ab6fdeefd2d090 410 Gene3D G3DSA:3.40.50.2000 1 205 5.8E-15 T 12-10-2018 MIM_c06770 c944573d0b4bf2519777db09b2ac92f0 92 Gene3D G3DSA:3.30.70.260 6 92 3.0E-28 T 12-10-2018 MIM_c06770 c944573d0b4bf2519777db09b2ac92f0 92 SUPERFAMILY SSF117991 8 92 1.7E-25 T 12-10-2018 IPR027471 YbeD-like domain superfamily MIM_c06770 c944573d0b4bf2519777db09b2ac92f0 92 Hamap MF_00659 UPF0250 protein YbeD [ybeD]. 4 92 21.17 T 12-10-2018 IPR007454 Uncharacterised protein family UPF0250 MIM_c06770 c944573d0b4bf2519777db09b2ac92f0 92 Pfam PF04359 Protein of unknown function (DUF493) 10 92 2.3E-28 T 12-10-2018 IPR007454 Uncharacterised protein family UPF0250 MIM_c01940 ff76d3ebbb139ff525d11e55a7d31f76 929 SUPERFAMILY SSF54665 55 173 5.23E-12 T 12-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily MIM_c01940 ff76d3ebbb139ff525d11e55a7d31f76 929 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 686 868 8.2E-16 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MIM_c01940 ff76d3ebbb139ff525d11e55a7d31f76 929 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 263 608 4.7E-53 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MIM_c01940 ff76d3ebbb139ff525d11e55a7d31f76 929 SUPERFAMILY SSF56003 264 927 8.64E-107 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 MIM_c01940 ff76d3ebbb139ff525d11e55a7d31f76 929 Gene3D G3DSA:3.30.365.10 754 928 1.6E-32 T 12-10-2018 MIM_c01940 ff76d3ebbb139ff525d11e55a7d31f76 929 Gene3D G3DSA:3.30.365.10 28 612 1.3E-62 T 12-10-2018 MIM_c19090 8a2a017a6b38c4832381fc8c67f3e9dc 186 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 16 87 4.1E-16 T 12-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 MIM_c19090 8a2a017a6b38c4832381fc8c67f3e9dc 186 Pfam PF02592 Putative vitamin uptake transporter 43 85 2.6E-9 T 12-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 MIM_c19090 8a2a017a6b38c4832381fc8c67f3e9dc 186 Pfam PF02592 Putative vitamin uptake transporter 89 174 1.0E-16 T 12-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 MIM_c19090 8a2a017a6b38c4832381fc8c67f3e9dc 186 Hamap MF_02088 Probable queuosine precursor transporter. 13 186 14.289 T 12-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 MIM_c08980 d0215c4e736bfa7c92013309dceadb6e 415 Pfam PF07690 Major Facilitator Superfamily 27 280 1.1E-10 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c08980 d0215c4e736bfa7c92013309dceadb6e 415 Gene3D G3DSA:1.20.1250.20 22 407 1.5E-25 T 12-10-2018 MIM_c08980 d0215c4e736bfa7c92013309dceadb6e 415 SUPERFAMILY SSF103473 23 411 1.96E-35 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c21120 cf06ea15552d5beb5ef5816d3ef53742 333 Gene3D G3DSA:3.40.190.150 37 323 2.0E-92 T 12-10-2018 MIM_c21120 cf06ea15552d5beb5ef5816d3ef53742 333 SUPERFAMILY SSF53850 122 296 1.49E-10 T 12-10-2018 MIM_c21120 cf06ea15552d5beb5ef5816d3ef53742 333 Gene3D G3DSA:3.40.190.10 135 258 2.0E-92 T 12-10-2018 MIM_c21120 cf06ea15552d5beb5ef5816d3ef53742 333 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 330 3.8E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c21120 cf06ea15552d5beb5ef5816d3ef53742 333 PIRSF PIRSF017082 1 332 2.1E-69 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c00470 bd77610799a059ec00d1fb825334a26f 321 SUPERFAMILY SSF46785 9 119 1.86E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c00470 bd77610799a059ec00d1fb825334a26f 321 Gene3D G3DSA:1.10.10.10 9 92 7.4E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c00470 bd77610799a059ec00d1fb825334a26f 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 70 2.2E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c00470 bd77610799a059ec00d1fb825334a26f 321 SUPERFAMILY SSF53850 100 302 1.41E-32 T 12-10-2018 MIM_c00470 bd77610799a059ec00d1fb825334a26f 321 Pfam PF03466 LysR substrate binding domain 101 302 3.7E-31 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c00470 bd77610799a059ec00d1fb825334a26f 321 Gene3D G3DSA:3.40.190.10 102 286 3.7E-33 T 12-10-2018 MIM_c00470 bd77610799a059ec00d1fb825334a26f 321 Gene3D G3DSA:3.40.190.10 173 276 3.7E-33 T 12-10-2018 MIM_c19190 94403caefc59cb94ab09e3c2a42ebbc3 584 SMART SM00388 352 422 2.8E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MIM_c19190 94403caefc59cb94ab09e3c2a42ebbc3 584 SMART SM00086 290 330 380.0 T 12-10-2018 IPR001610 PAC motif MIM_c19190 94403caefc59cb94ab09e3c2a42ebbc3 584 SMART SM00086 180 222 0.018 T 12-10-2018 IPR001610 PAC motif MIM_c19190 94403caefc59cb94ab09e3c2a42ebbc3 584 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 105 229 1.4E-24 T 12-10-2018 IPR000014 PAS domain MIM_c19190 94403caefc59cb94ab09e3c2a42ebbc3 584 Gene3D G3DSA:3.30.565.10 421 576 4.4E-38 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c19190 94403caefc59cb94ab09e3c2a42ebbc3 584 Pfam PF00512 His Kinase A (phospho-acceptor) domain 353 419 3.4E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MIM_c19190 94403caefc59cb94ab09e3c2a42ebbc3 584 SUPERFAMILY SSF55785 219 328 9.6E-8 T 12-10-2018 IPR035965 PAS domain superfamily MIM_c19190 94403caefc59cb94ab09e3c2a42ebbc3 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 519 529 8.9E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c19190 94403caefc59cb94ab09e3c2a42ebbc3 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 530 548 8.9E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c19190 94403caefc59cb94ab09e3c2a42ebbc3 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 503 517 8.9E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c19190 94403caefc59cb94ab09e3c2a42ebbc3 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 554 567 8.9E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c19190 94403caefc59cb94ab09e3c2a42ebbc3 584 Gene3D G3DSA:3.30.450.20 104 236 2.9E-25 T 12-10-2018 MIM_c19190 94403caefc59cb94ab09e3c2a42ebbc3 584 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 465 567 1.7E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c19190 94403caefc59cb94ab09e3c2a42ebbc3 584 Pfam PF13188 PAS domain 234 291 6.6E-4 T 12-10-2018 IPR000014 PAS domain MIM_c19190 94403caefc59cb94ab09e3c2a42ebbc3 584 Gene3D G3DSA:1.10.287.130 357 419 2.5E-18 T 12-10-2018 MIM_c19190 94403caefc59cb94ab09e3c2a42ebbc3 584 SMART SM00091 234 308 29.0 T 12-10-2018 IPR000014 PAS domain MIM_c19190 94403caefc59cb94ab09e3c2a42ebbc3 584 SMART SM00091 106 173 1.3E-9 T 12-10-2018 IPR000014 PAS domain MIM_c19190 94403caefc59cb94ab09e3c2a42ebbc3 584 SUPERFAMILY SSF55785 95 220 2.62E-24 T 12-10-2018 IPR035965 PAS domain superfamily MIM_c19190 94403caefc59cb94ab09e3c2a42ebbc3 584 SUPERFAMILY SSF55874 410 573 7.78E-37 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c19190 94403caefc59cb94ab09e3c2a42ebbc3 584 SMART SM00387 464 570 2.5E-28 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c19190 94403caefc59cb94ab09e3c2a42ebbc3 584 Pfam PF08448 PAS fold 115 224 1.1E-15 T 12-10-2018 IPR013656 PAS fold-4 MIM_c19190 94403caefc59cb94ab09e3c2a42ebbc3 584 SUPERFAMILY SSF47384 343 419 8.24E-9 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MIM_c05240 64c16b56a41117c91a365f7a6ed5254e 389 Gene3D G3DSA:1.10.3090.10 128 345 1.3E-26 T 12-10-2018 MIM_c05240 64c16b56a41117c91a365f7a6ed5254e 389 Gene3D G3DSA:3.30.460.10 2 127 3.5E-27 T 12-10-2018 MIM_c05240 64c16b56a41117c91a365f7a6ed5254e 389 PIRSF PIRSF000813 7 229 7.4E-113 T 12-10-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 MIM_c05240 64c16b56a41117c91a365f7a6ed5254e 389 PIRSF PIRSF000813 220 387 6.3E-12 T 12-10-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 MIM_c05240 64c16b56a41117c91a365f7a6ed5254e 389 Pfam PF01743 Poly A polymerase head domain 9 128 1.6E-16 T 12-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 MIM_c05240 64c16b56a41117c91a365f7a6ed5254e 389 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 153 214 4.9E-8 T 12-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 MIM_c05240 64c16b56a41117c91a365f7a6ed5254e 389 SUPERFAMILY SSF81301 6 125 6.87E-30 T 12-10-2018 MIM_c05240 64c16b56a41117c91a365f7a6ed5254e 389 SUPERFAMILY SSF81891 127 301 3.27E-30 T 12-10-2018 MIM_c05070 c69c8c5fc411ec4960ee5cac95902300 177 PIRSF PIRSF039093 1 177 2.3E-85 T 12-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 MIM_c05070 c69c8c5fc411ec4960ee5cac95902300 177 Gene3D G3DSA:3.60.20.10 2 177 4.9E-65 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MIM_c05070 c69c8c5fc411ec4960ee5cac95902300 177 SUPERFAMILY SSF56235 3 177 2.24E-57 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MIM_c05070 c69c8c5fc411ec4960ee5cac95902300 177 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 6 177 40.852 T 12-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 MIM_c05070 c69c8c5fc411ec4960ee5cac95902300 177 Pfam PF00227 Proteasome subunit 5 175 9.1E-21 T 12-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 MIM_c05070 c69c8c5fc411ec4960ee5cac95902300 177 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 7 177 5.7E-84 T 12-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 MIM_c23810 05519379afe42c36eefbc79cf166ac9b 250 SUPERFAMILY SSF54768 106 221 2.51E-25 T 12-10-2018 MIM_c23810 05519379afe42c36eefbc79cf166ac9b 250 SMART SM00358 153 221 3.0E-18 T 12-10-2018 IPR014720 Double-stranded RNA-binding domain MIM_c23810 05519379afe42c36eefbc79cf166ac9b 250 Gene3D G3DSA:3.30.160.20 151 222 4.8E-18 T 12-10-2018 MIM_c23810 05519379afe42c36eefbc79cf166ac9b 250 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 7 219 2.0E-69 T 12-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 MIM_c23810 05519379afe42c36eefbc79cf166ac9b 250 Pfam PF00035 Double-stranded RNA binding motif 153 220 5.5E-9 T 12-10-2018 IPR014720 Double-stranded RNA-binding domain MIM_c23810 05519379afe42c36eefbc79cf166ac9b 250 SMART SM00535 18 146 1.7E-50 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 MIM_c23810 05519379afe42c36eefbc79cf166ac9b 250 Gene3D G3DSA:1.10.1520.10 1 145 1.8E-42 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 MIM_c23810 05519379afe42c36eefbc79cf166ac9b 250 SUPERFAMILY SSF69065 2 150 1.31E-44 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 MIM_c23810 05519379afe42c36eefbc79cf166ac9b 250 Hamap MF_00104 Ribonuclease 3 [rnc]. 6 217 28.019 T 12-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 MIM_c23810 05519379afe42c36eefbc79cf166ac9b 250 ProSitePatterns PS00517 Ribonuclease III family signature. 35 43 - T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 MIM_c23810 05519379afe42c36eefbc79cf166ac9b 250 Pfam PF14622 Ribonuclease-III-like 16 136 3.2E-33 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 MIM_c35040 8787a8f975b7e1b7a7cb5d9d19970a4f 399 SUPERFAMILY SSF53822 25 391 7.06E-59 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c35040 8787a8f975b7e1b7a7cb5d9d19970a4f 399 Gene3D G3DSA:3.40.50.2300 27 330 1.3E-60 T 12-10-2018 MIM_c35040 8787a8f975b7e1b7a7cb5d9d19970a4f 399 Pfam PF13458 Periplasmic binding protein 25 381 1.7E-43 T 12-10-2018 IPR028081 Leucine-binding protein domain MIM_c35040 8787a8f975b7e1b7a7cb5d9d19970a4f 399 Gene3D G3DSA:3.40.50.2300 147 277 1.3E-60 T 12-10-2018 MIM_c02530 245e67056621bad5b559b7eab4e8fe6b 306 TIGRFAM TIGR02207 lipid_A_htrB: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase 6 306 4.2E-131 T 12-10-2018 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 MIM_c02530 245e67056621bad5b559b7eab4e8fe6b 306 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 6 297 2.0E-96 T 12-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 MIM_c02530 245e67056621bad5b559b7eab4e8fe6b 306 Hamap MF_01943 Lipid A biosynthesis palmitoleoyltransferase [lpxP]. 3 306 64.71 T 12-10-2018 IPR030857 Lipid A biosynthesis palmitoleoyltransferase, LpxP GO:0008951|GO:0009409|GO:0036104 MIM_c02530 245e67056621bad5b559b7eab4e8fe6b 306 PIRSF PIRSF026649 2 306 2.3E-92 T 12-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 MIM_c02530 245e67056621bad5b559b7eab4e8fe6b 306 Hamap MF_01942 Lipid A biosynthesis lauroyltransferase [lpxL]. 4 306 48.947 T 12-10-2018 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 MIM_c11950 08690420137498a7f236d34879f7bcb5 319 PIRSF PIRSF017082 2 319 1.6E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c11950 08690420137498a7f236d34879f7bcb5 319 Gene3D G3DSA:3.40.190.10 123 244 4.4E-101 T 12-10-2018 MIM_c11950 08690420137498a7f236d34879f7bcb5 319 Gene3D G3DSA:3.40.190.150 28 308 4.4E-101 T 12-10-2018 MIM_c11950 08690420137498a7f236d34879f7bcb5 319 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 315 3.5E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c11950 08690420137498a7f236d34879f7bcb5 319 SUPERFAMILY SSF53850 112 282 1.72E-14 T 12-10-2018 MIM_c37970 6bd741188c3655c67624ca359f5ea70f 153 SMART SM00871 1 153 4.9E-20 T 12-10-2018 IPR010499 Bacterial transcription activator, effector binding MIM_c37970 6bd741188c3655c67624ca359f5ea70f 153 Pfam PF14526 Integron-associated effector binding protein 2 147 2.7E-19 T 12-10-2018 IPR029441 Integron-associated effector binding protein MIM_c37970 6bd741188c3655c67624ca359f5ea70f 153 SUPERFAMILY SSF55136 2 140 6.54E-13 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily MIM_c37970 6bd741188c3655c67624ca359f5ea70f 153 Gene3D G3DSA:3.20.80.10 1 152 5.1E-39 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily MIM_c02470 b8e9119cad75a7134ec0f4d89021e814 239 Pfam PF09339 IclR helix-turn-helix domain 22 71 3.3E-11 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c02470 b8e9119cad75a7134ec0f4d89021e814 239 Gene3D G3DSA:3.30.450.40 87 165 3.8E-14 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c02470 b8e9119cad75a7134ec0f4d89021e814 239 SUPERFAMILY SSF46785 20 89 7.19E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c02470 b8e9119cad75a7134ec0f4d89021e814 239 Gene3D G3DSA:1.10.10.10 6 80 3.8E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c02470 b8e9119cad75a7134ec0f4d89021e814 239 Pfam PF01614 Bacterial transcriptional regulator 170 226 3.1E-6 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal MIM_c02470 b8e9119cad75a7134ec0f4d89021e814 239 Gene3D G3DSA:3.30.450.40 166 238 5.1E-11 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c02470 b8e9119cad75a7134ec0f4d89021e814 239 SUPERFAMILY SSF55781 77 236 1.77E-24 T 12-10-2018 MIM_c02470 b8e9119cad75a7134ec0f4d89021e814 239 SMART SM00346 20 109 3.8E-11 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c24030 ab3281cd9170517ec161d3706f679f8b 316 Pfam PF01479 S4 domain 26 72 8.2E-8 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c24030 ab3281cd9170517ec161d3706f679f8b 316 Pfam PF00849 RNA pseudouridylate synthase 102 250 6.9E-30 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MIM_c24030 ab3281cd9170517ec161d3706f679f8b 316 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 23 313 2.6E-79 T 12-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MIM_c24030 ab3281cd9170517ec161d3706f679f8b 316 Gene3D G3DSA:3.10.290.10 17 77 1.0E-14 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MIM_c24030 ab3281cd9170517ec161d3706f679f8b 316 SUPERFAMILY SSF55174 25 76 5.74E-9 T 12-10-2018 MIM_c24030 ab3281cd9170517ec161d3706f679f8b 316 Gene3D G3DSA:3.30.2350.10 94 315 1.7E-75 T 12-10-2018 MIM_c24030 ab3281cd9170517ec161d3706f679f8b 316 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 140 154 - T 12-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MIM_c24030 ab3281cd9170517ec161d3706f679f8b 316 SUPERFAMILY SSF55120 89 313 1.23E-65 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MIM_c24030 ab3281cd9170517ec161d3706f679f8b 316 SMART SM00363 26 85 2.5E-7 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c16260 4896da7d668b5d7396106d9e6a7cd60e 354 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 120 225 5.5E-25 T 12-10-2018 IPR031571 Flp pilus assembly protein RcpC/CpaB domain MIM_c16260 4896da7d668b5d7396106d9e6a7cd60e 354 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 13 267 3.6E-46 T 12-10-2018 IPR017592 Pilus assembly, Flp-type CpaB MIM_c00330 159512d43ead0ac2e02be4d74597af28 304 Gene3D G3DSA:2.120.10.30 37 303 9.2E-67 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MIM_c00330 159512d43ead0ac2e02be4d74597af28 304 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 45 282 5.0E-38 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region MIM_c00330 159512d43ead0ac2e02be4d74597af28 304 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 266 284 9.8E-9 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MIM_c00330 159512d43ead0ac2e02be4d74597af28 304 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 162 184 9.8E-9 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MIM_c00330 159512d43ead0ac2e02be4d74597af28 304 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 223 240 9.8E-9 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MIM_c00330 159512d43ead0ac2e02be4d74597af28 304 SUPERFAMILY SSF63829 42 302 8.28E-60 T 12-10-2018 MIM_c05660 1f6a64adfdfc2ccf8ed0eee60af90ce8 259 Gene3D G3DSA:2.40.100.10 117 257 9.2E-53 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily MIM_c05660 1f6a64adfdfc2ccf8ed0eee60af90ce8 259 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 18 240 1.9E-44 T 12-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 MIM_c05660 1f6a64adfdfc2ccf8ed0eee60af90ce8 259 SUPERFAMILY SSF160467 14 123 4.71E-13 T 12-10-2018 MIM_c05660 1f6a64adfdfc2ccf8ed0eee60af90ce8 259 SMART SM00796 12 232 1.8E-72 T 12-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D MIM_c05660 1f6a64adfdfc2ccf8ed0eee60af90ce8 259 Gene3D G3DSA:3.30.1360.40 8 104 4.2E-13 T 12-10-2018 MIM_c05660 1f6a64adfdfc2ccf8ed0eee60af90ce8 259 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 13 230 3.9E-61 T 12-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D MIM_c05660 1f6a64adfdfc2ccf8ed0eee60af90ce8 259 SUPERFAMILY SSF50891 118 248 7.59E-44 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily MIM_c11690 fbeeb6a5553f8ed3f4ca7e244230a4be 418 SUPERFAMILY SSF53659 3 418 5.38E-144 T 12-10-2018 MIM_c11690 fbeeb6a5553f8ed3f4ca7e244230a4be 418 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 3 418 3.2E-223 T 12-10-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 MIM_c11690 fbeeb6a5553f8ed3f4ca7e244230a4be 418 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 305 324 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 MIM_c11690 fbeeb6a5553f8ed3f4ca7e244230a4be 418 Gene3D G3DSA:3.40.718.10 1 418 6.9E-188 T 12-10-2018 MIM_c11690 fbeeb6a5553f8ed3f4ca7e244230a4be 418 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 31 412 5.5E-115 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MIM_c11690 fbeeb6a5553f8ed3f4ca7e244230a4be 418 SMART SM01329 30 414 3.8E-172 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MIM_c19900 79ad744a29f06045c19a8d79d2a3249b 462 Pfam PF01425 Amidase 31 443 3.7E-102 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MIM_c19900 79ad744a29f06045c19a8d79d2a3249b 462 Gene3D G3DSA:3.90.1300.10 13 461 1.0E-127 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MIM_c19900 79ad744a29f06045c19a8d79d2a3249b 462 ProSitePatterns PS00571 Amidases signature. 161 192 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 MIM_c19900 79ad744a29f06045c19a8d79d2a3249b 462 SUPERFAMILY SSF75304 14 453 4.06E-124 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MIM_c20230 452762f33ddfe2be47dde0b0afa00553 320 Gene3D G3DSA:3.40.190.10 124 245 1.9E-80 T 12-10-2018 MIM_c20230 452762f33ddfe2be47dde0b0afa00553 320 Gene3D G3DSA:3.40.190.150 29 310 1.9E-80 T 12-10-2018 MIM_c20230 452762f33ddfe2be47dde0b0afa00553 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 316 1.8E-60 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c20230 452762f33ddfe2be47dde0b0afa00553 320 SUPERFAMILY SSF53850 30 271 8.03E-8 T 12-10-2018 MIM_c20230 452762f33ddfe2be47dde0b0afa00553 320 PIRSF PIRSF017082 5 320 1.3E-64 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c37490 e068bb1baba4a4fcf5de5bf0543e7071 295 Gene3D G3DSA:1.10.10.10 1 81 3.9E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c37490 e068bb1baba4a4fcf5de5bf0543e7071 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 61 2.5E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c37490 e068bb1baba4a4fcf5de5bf0543e7071 295 SUPERFAMILY SSF46785 1 108 8.33E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c37490 e068bb1baba4a4fcf5de5bf0543e7071 295 Gene3D G3DSA:3.40.190.290 88 293 4.1E-31 T 12-10-2018 MIM_c37490 e068bb1baba4a4fcf5de5bf0543e7071 295 Pfam PF03466 LysR substrate binding domain 85 284 2.8E-38 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c37490 e068bb1baba4a4fcf5de5bf0543e7071 295 SUPERFAMILY SSF53850 86 287 4.34E-34 T 12-10-2018 MIM_c18650 e4074cdf0b26ee4ac713864b105de97e 626 Gene3D G3DSA:3.40.190.290 413 622 1.9E-22 T 12-10-2018 MIM_c18650 e4074cdf0b26ee4ac713864b105de97e 626 Gene3D G3DSA:1.10.10.10 318 404 5.7E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c18650 e4074cdf0b26ee4ac713864b105de97e 626 SUPERFAMILY SSF53850 413 621 2.35E-22 T 12-10-2018 MIM_c18650 e4074cdf0b26ee4ac713864b105de97e 626 Gene3D G3DSA:1.10.10.10 12 99 7.7E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c18650 e4074cdf0b26ee4ac713864b105de97e 626 Pfam PF03466 LysR substrate binding domain 411 618 3.8E-22 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c18650 e4074cdf0b26ee4ac713864b105de97e 626 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 16 70 8.9E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c18650 e4074cdf0b26ee4ac713864b105de97e 626 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 322 382 8.4E-13 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c18650 e4074cdf0b26ee4ac713864b105de97e 626 SUPERFAMILY SSF46785 11 84 9.98E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c18650 e4074cdf0b26ee4ac713864b105de97e 626 SUPERFAMILY SSF46785 320 417 2.61E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c04590 4f0983934feabb33a8c36d996d4ad3a4 199 Gene3D G3DSA:3.40.30.10 41 192 8.4E-9 T 12-10-2018 MIM_c04590 4f0983934feabb33a8c36d996d4ad3a4 199 SUPERFAMILY SSF52833 28 194 5.29E-13 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c41090 c865065945eaf9d8c44ea7b714d1f331 317 PIRSF PIRSF017082 1 317 2.2E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c41090 c865065945eaf9d8c44ea7b714d1f331 317 SUPERFAMILY SSF53850 114 288 2.17E-11 T 12-10-2018 MIM_c41090 c865065945eaf9d8c44ea7b714d1f331 317 Gene3D G3DSA:3.40.190.150 30 314 6.2E-104 T 12-10-2018 MIM_c41090 c865065945eaf9d8c44ea7b714d1f331 317 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 316 1.1E-74 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c41090 c865065945eaf9d8c44ea7b714d1f331 317 Gene3D G3DSA:3.40.190.10 126 249 6.2E-104 T 12-10-2018 MIM_c04740 fb022cbf6e71d453f0f120ab05253bf9 488 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 379 469 4.5E-7 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MIM_c04740 fb022cbf6e71d453f0f120ab05253bf9 488 Gene3D G3DSA:3.40.50.720 143 255 6.1E-16 T 12-10-2018 MIM_c04740 fb022cbf6e71d453f0f120ab05253bf9 488 Gene3D G3DSA:1.10.1060.10 10 142 3.6E-23 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MIM_c04740 fb022cbf6e71d453f0f120ab05253bf9 488 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 487 2.2E-224 T 12-10-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 MIM_c04740 fb022cbf6e71d453f0f120ab05253bf9 488 Gene3D G3DSA:3.50.50.60 256 413 1.4E-38 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c04740 fb022cbf6e71d453f0f120ab05253bf9 488 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 24 131 4.3E-25 T 12-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 MIM_c04740 fb022cbf6e71d453f0f120ab05253bf9 488 PRINTS PR00419 Adrenodoxin reductase family signature 294 308 1.2E-20 T 12-10-2018 MIM_c04740 fb022cbf6e71d453f0f120ab05253bf9 488 PRINTS PR00419 Adrenodoxin reductase family signature 145 167 1.2E-20 T 12-10-2018 MIM_c04740 fb022cbf6e71d453f0f120ab05253bf9 488 PRINTS PR00419 Adrenodoxin reductase family signature 168 181 1.2E-20 T 12-10-2018 MIM_c04740 fb022cbf6e71d453f0f120ab05253bf9 488 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 144 328 1.1E-20 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MIM_c04740 fb022cbf6e71d453f0f120ab05253bf9 488 SUPERFAMILY SSF46548 2 154 7.85E-39 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MIM_c04740 fb022cbf6e71d453f0f120ab05253bf9 488 SUPERFAMILY SSF51971 398 482 3.41E-10 T 12-10-2018 MIM_c04740 fb022cbf6e71d453f0f120ab05253bf9 488 SUPERFAMILY SSF51971 143 414 5.53E-65 T 12-10-2018 MIM_c26740 b6baa488ed6c9b42712e7535fb31d02d 235 SMART SM00862 154 231 3.0E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MIM_c26740 b6baa488ed6c9b42712e7535fb31d02d 235 Gene3D G3DSA:3.40.50.2300 3 132 3.8E-39 T 12-10-2018 MIM_c26740 b6baa488ed6c9b42712e7535fb31d02d 235 SUPERFAMILY SSF46894 136 231 2.24E-24 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MIM_c26740 b6baa488ed6c9b42712e7535fb31d02d 235 SUPERFAMILY SSF52172 6 130 2.85E-42 T 12-10-2018 IPR011006 CheY-like superfamily MIM_c26740 b6baa488ed6c9b42712e7535fb31d02d 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 231 8.8E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MIM_c26740 b6baa488ed6c9b42712e7535fb31d02d 235 Pfam PF00072 Response regulator receiver domain 8 118 9.8E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c26740 b6baa488ed6c9b42712e7535fb31d02d 235 Gene3D G3DSA:1.10.10.10 133 235 2.4E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c26740 b6baa488ed6c9b42712e7535fb31d02d 235 SMART SM00448 6 117 2.5E-43 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c10780 20ff90ac62a6a53818de41b4571137cc 186 SUPERFAMILY SSF54060 12 131 5.12E-26 T 12-10-2018 MIM_c10780 20ff90ac62a6a53818de41b4571137cc 186 Pfam PF07463 NUMOD4 motif 12 70 3.8E-16 T 12-10-2018 IPR010902 NUMOD4 GO:0016788 MIM_c10780 20ff90ac62a6a53818de41b4571137cc 186 Gene3D G3DSA:3.90.75.20 13 132 1.0E-27 T 12-10-2018 MIM_c10780 20ff90ac62a6a53818de41b4571137cc 186 Pfam PF13392 HNH endonuclease 80 123 2.4E-12 T 12-10-2018 IPR003615 HNH nuclease MIM_c14800 5c886c19fc3b0e5f86db0f225acdb941 304 SUPERFAMILY SSF48576 7 295 1.64E-82 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily MIM_c14800 5c886c19fc3b0e5f86db0f225acdb941 304 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 223 235 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site MIM_c14800 5c886c19fc3b0e5f86db0f225acdb941 304 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 93 109 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site MIM_c14800 5c886c19fc3b0e5f86db0f225acdb941 304 Pfam PF00348 Polyprenyl synthetase 36 276 1.3E-54 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 MIM_c14800 5c886c19fc3b0e5f86db0f225acdb941 304 Gene3D G3DSA:1.10.600.10 8 304 1.3E-90 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily MIM_c23970 edd8aa970df9ddec8848edb5a531c03f 200 TIGRFAM TIGR00172 maf: septum formation protein Maf 5 187 5.0E-40 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 MIM_c23970 edd8aa970df9ddec8848edb5a531c03f 200 SUPERFAMILY SSF52972 5 188 1.37E-53 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MIM_c23970 edd8aa970df9ddec8848edb5a531c03f 200 Hamap MF_00528 Septum formation protein Maf [maf]. 7 193 26.997 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 MIM_c23970 edd8aa970df9ddec8848edb5a531c03f 200 PIRSF PIRSF006305 1 195 1.3E-43 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 MIM_c23970 edd8aa970df9ddec8848edb5a531c03f 200 Pfam PF02545 Maf-like protein 7 187 3.3E-42 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 MIM_c23970 edd8aa970df9ddec8848edb5a531c03f 200 Gene3D G3DSA:3.90.950.10 6 195 1.0E-52 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MIM_c31430 3bac563a84e3b39a2f1aa5728acf2c1b 322 SUPERFAMILY SSF53850 113 290 4.35E-13 T 12-10-2018 MIM_c31430 3bac563a84e3b39a2f1aa5728acf2c1b 322 Gene3D G3DSA:3.40.190.10 126 247 9.8E-91 T 12-10-2018 MIM_c31430 3bac563a84e3b39a2f1aa5728acf2c1b 322 PIRSF PIRSF017082 1 321 4.3E-85 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c31430 3bac563a84e3b39a2f1aa5728acf2c1b 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 317 1.6E-70 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c31430 3bac563a84e3b39a2f1aa5728acf2c1b 322 Gene3D G3DSA:3.40.190.150 30 307 9.8E-91 T 12-10-2018 MIM_c14370 81c2ad52171729fa23589b86ea4e4a61 139 Pfam PF00101 Ribulose bisphosphate carboxylase, small chain 5 103 1.3E-39 T 12-10-2018 IPR000894 Ribulose bisphosphate carboxylase small chain, domain KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 MIM_c14370 81c2ad52171729fa23589b86ea4e4a61 139 SUPERFAMILY SSF55239 1 133 1.83E-53 T 12-10-2018 IPR036385 Ribulose bisphosphate carboxylase, small subunit superfamily KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 MIM_c14370 81c2ad52171729fa23589b86ea4e4a61 139 Gene3D G3DSA:3.30.190.10 1 139 2.5E-57 T 12-10-2018 IPR036385 Ribulose bisphosphate carboxylase, small subunit superfamily KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 MIM_c14370 81c2ad52171729fa23589b86ea4e4a61 139 SMART SM00961 4 103 2.7E-52 T 12-10-2018 IPR000894 Ribulose bisphosphate carboxylase small chain, domain KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 MIM_c01150 70c71bbc7d2b84c78621c0462411cebf 292 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 279 8.9E-40 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c03250 a6c957debe0b2fc12caec888a686e581 396 SUPERFAMILY SSF53383 14 392 3.06E-113 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c03250 a6c957debe0b2fc12caec888a686e581 396 Gene3D G3DSA:3.40.640.10 54 297 1.1E-129 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c03250 a6c957debe0b2fc12caec888a686e581 396 Gene3D G3DSA:3.90.1150.10 19 384 1.1E-129 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c03250 a6c957debe0b2fc12caec888a686e581 396 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 10 394 64.523 T 12-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 MIM_c03250 a6c957debe0b2fc12caec888a686e581 396 Pfam PF00202 Aminotransferase class-III 20 390 1.6E-98 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MIM_c03250 a6c957debe0b2fc12caec888a686e581 396 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 216 253 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MIM_c03250 a6c957debe0b2fc12caec888a686e581 396 PIRSF PIRSF000521 148 394 5.3E-27 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MIM_c03250 a6c957debe0b2fc12caec888a686e581 396 PIRSF PIRSF000521 9 159 7.1E-10 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MIM_c31450 2cf04e351007f6a374b9ab6ee2d49893 528 Gene3D G3DSA:3.60.20.40 355 528 1.4E-55 T 12-10-2018 MIM_c31450 2cf04e351007f6a374b9ab6ee2d49893 528 SUPERFAMILY SSF56235 4 528 2.32E-161 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MIM_c31450 2cf04e351007f6a374b9ab6ee2d49893 528 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 17 520 8.7E-115 T 12-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 MIM_c31450 2cf04e351007f6a374b9ab6ee2d49893 528 Pfam PF01019 Gamma-glutamyltranspeptidase 32 523 2.6E-137 T 12-10-2018 MIM_c31450 2cf04e351007f6a374b9ab6ee2d49893 528 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 350 368 2.2E-38 T 12-10-2018 MIM_c31450 2cf04e351007f6a374b9ab6ee2d49893 528 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 39 64 2.2E-38 T 12-10-2018 MIM_c31450 2cf04e351007f6a374b9ab6ee2d49893 528 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 254 273 2.2E-38 T 12-10-2018 MIM_c31450 2cf04e351007f6a374b9ab6ee2d49893 528 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 374 392 2.2E-38 T 12-10-2018 MIM_c31450 2cf04e351007f6a374b9ab6ee2d49893 528 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 109 127 2.2E-38 T 12-10-2018 MIM_c31450 2cf04e351007f6a374b9ab6ee2d49893 528 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 405 420 2.2E-38 T 12-10-2018 MIM_c31450 2cf04e351007f6a374b9ab6ee2d49893 528 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 429 446 2.2E-38 T 12-10-2018 MIM_c31450 2cf04e351007f6a374b9ab6ee2d49893 528 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 127 146 2.2E-38 T 12-10-2018 MIM_c31450 2cf04e351007f6a374b9ab6ee2d49893 528 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 225 241 2.2E-38 T 12-10-2018 MIM_c31450 2cf04e351007f6a374b9ab6ee2d49893 528 Gene3D G3DSA:1.10.246.130 241 354 4.8E-25 T 12-10-2018 MIM_c27260 876766cfe34ba652132477b247d2766a 237 SUPERFAMILY SSF52540 5 234 1.09E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c27260 876766cfe34ba652132477b247d2766a 237 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c27260 876766cfe34ba652132477b247d2766a 237 SMART SM00382 30 214 1.3E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c27260 876766cfe34ba652132477b247d2766a 237 Pfam PF00005 ABC transporter 21 165 1.9E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c27260 876766cfe34ba652132477b247d2766a 237 Gene3D G3DSA:3.40.50.300 1 237 4.4E-59 T 12-10-2018 MIM_c16460 f42c04577e8d8303bc25355489923e1d 190 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 4 187 7.0E-53 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 MIM_c16460 f42c04577e8d8303bc25355489923e1d 190 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 54 76 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MIM_c16460 f42c04577e8d8303bc25355489923e1d 190 Gene3D G3DSA:1.20.120.1760 5 181 1.4E-11 T 12-10-2018 MIM_c16460 f42c04577e8d8303bc25355489923e1d 190 Pfam PF01066 CDP-alcohol phosphatidyltransferase 4 76 1.5E-16 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MIM_c16460 f42c04577e8d8303bc25355489923e1d 190 PIRSF PIRSF000847 1 190 9.7E-47 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 MIM_c11230 2a2b73d479532c7fa3b5938cc06072f8 458 Gene3D G3DSA:1.20.1740.10 11 453 3.8E-81 T 12-10-2018 MIM_c11230 2a2b73d479532c7fa3b5938cc06072f8 458 Pfam PF13520 Amino acid permease 15 421 3.2E-45 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MIM_c11230 2a2b73d479532c7fa3b5938cc06072f8 458 PIRSF PIRSF006060 1 457 8.7E-75 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MIM_c29420 6c7d29da0d6611b865486ca7bb64ffda 449 SUPERFAMILY SSF51246 331 444 1.05E-43 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MIM_c29420 6c7d29da0d6611b865486ca7bb64ffda 449 SMART SM00878 336 441 1.7E-64 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MIM_c29420 6c7d29da0d6611b865486ca7bb64ffda 449 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 1.9E-76 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MIM_c29420 6c7d29da0d6611b865486ca7bb64ffda 449 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MIM_c29420 6c7d29da0d6611b865486ca7bb64ffda 449 Gene3D G3DSA:3.40.50.20 1 85 5.1E-35 T 12-10-2018 MIM_c29420 6c7d29da0d6611b865486ca7bb64ffda 449 Gene3D G3DSA:3.30.470.20 87 433 7.7E-152 T 12-10-2018 MIM_c29420 6c7d29da0d6611b865486ca7bb64ffda 449 Gene3D G3DSA:3.30.1490.20 131 203 7.7E-152 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MIM_c29420 6c7d29da0d6611b865486ca7bb64ffda 449 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MIM_c29420 6c7d29da0d6611b865486ca7bb64ffda 449 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 446 1.1E-218 T 12-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 MIM_c29420 6c7d29da0d6611b865486ca7bb64ffda 449 Pfam PF02785 Biotin carboxylase C-terminal domain 336 441 5.0E-39 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MIM_c29420 6c7d29da0d6611b865486ca7bb64ffda 449 SUPERFAMILY SSF56059 83 346 1.34E-68 T 12-10-2018 MIM_c29420 6c7d29da0d6611b865486ca7bb64ffda 449 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 5.0E-45 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MIM_c29420 6c7d29da0d6611b865486ca7bb64ffda 449 SUPERFAMILY SSF52440 1 113 7.05E-48 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MIM_c20200 bbf2edc0bd77301a28ee68632b77e04d 452 Pfam PF03972 MmgE/PrpD family 6 435 2.0E-110 T 12-10-2018 IPR005656 MmgE/PrpD GO:0016829 MIM_c20200 bbf2edc0bd77301a28ee68632b77e04d 452 Gene3D G3DSA:3.30.1330.120 262 391 1.0E-27 T 12-10-2018 MIM_c20200 bbf2edc0bd77301a28ee68632b77e04d 452 SUPERFAMILY SSF103378 2 443 3.66E-102 T 12-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 MIM_c20200 bbf2edc0bd77301a28ee68632b77e04d 452 Gene3D G3DSA:1.10.4100.10 1 247 6.2E-68 T 12-10-2018 MIM_c12060 82c5c6c223df66008e42457aa8ea4e52 392 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 MIM_c12060 82c5c6c223df66008e42457aa8ea4e52 392 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 12-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 MIM_c12060 82c5c6c223df66008e42457aa8ea4e52 392 Gene3D G3DSA:3.40.47.10 126 386 1.4E-139 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c12060 82c5c6c223df66008e42457aa8ea4e52 392 Pfam PF02803 Thiolase, C-terminal domain 270 390 2.9E-43 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 MIM_c12060 82c5c6c223df66008e42457aa8ea4e52 392 SUPERFAMILY SSF53901 271 391 1.66E-41 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c12060 82c5c6c223df66008e42457aa8ea4e52 392 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 1.8E-126 T 12-10-2018 IPR002155 Thiolase GO:0016747 MIM_c12060 82c5c6c223df66008e42457aa8ea4e52 392 PIRSF PIRSF000429 1 392 7.0E-118 T 12-10-2018 IPR002155 Thiolase GO:0016747 MIM_c12060 82c5c6c223df66008e42457aa8ea4e52 392 Gene3D G3DSA:3.40.47.10 6 275 1.4E-139 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c12060 82c5c6c223df66008e42457aa8ea4e52 392 SUPERFAMILY SSF53901 1 266 7.77E-70 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c12060 82c5c6c223df66008e42457aa8ea4e52 392 Pfam PF00108 Thiolase, N-terminal domain 5 261 6.4E-63 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 MIM_c09160 464861aa14a58963b0976a62192dbd64 290 Hamap MF_01805 Segregation and condensation protein A [scpA]. 50 284 20.891 T 12-10-2018 IPR003768 Segregation and condensation protein A MIM_c09160 464861aa14a58963b0976a62192dbd64 290 Pfam PF02616 Segregation and condensation protein ScpA 67 282 7.0E-32 T 12-10-2018 IPR003768 Segregation and condensation protein A MIM_c05980 093c23197e2086d25f0c4ec6cbb865c4 301 SUPERFAMILY SSF53850 91 293 4.19E-27 T 12-10-2018 MIM_c05980 093c23197e2086d25f0c4ec6cbb865c4 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.3E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c05980 093c23197e2086d25f0c4ec6cbb865c4 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.3E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c05980 093c23197e2086d25f0c4ec6cbb865c4 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.3E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c05980 093c23197e2086d25f0c4ec6cbb865c4 301 Pfam PF03466 LysR substrate binding domain 89 292 2.1E-30 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c05980 093c23197e2086d25f0c4ec6cbb865c4 301 Gene3D G3DSA:1.10.10.10 1 88 9.1E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c05980 093c23197e2086d25f0c4ec6cbb865c4 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 4.9E-23 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c05980 093c23197e2086d25f0c4ec6cbb865c4 301 Gene3D G3DSA:3.40.190.290 91 295 1.7E-34 T 12-10-2018 MIM_c05980 093c23197e2086d25f0c4ec6cbb865c4 301 SUPERFAMILY SSF46785 1 110 1.39E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c24980 8133bc3acff3e2f35f9942ac524e1979 330 SUPERFAMILY SSF53850 101 290 4.21E-7 T 12-10-2018 MIM_c24980 8133bc3acff3e2f35f9942ac524e1979 330 PIRSF PIRSF017082 2 330 5.3E-52 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c24980 8133bc3acff3e2f35f9942ac524e1979 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 326 1.1E-48 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c24980 8133bc3acff3e2f35f9942ac524e1979 330 Gene3D G3DSA:3.40.190.10 128 254 5.7E-70 T 12-10-2018 MIM_c24980 8133bc3acff3e2f35f9942ac524e1979 330 Gene3D G3DSA:3.40.190.150 37 320 5.7E-70 T 12-10-2018 MIM_c25230 32c1788bd56673f9f1924d596f63b482 302 Gene3D G3DSA:3.40.190.10 96 293 4.9E-47 T 12-10-2018 MIM_c25230 32c1788bd56673f9f1924d596f63b482 302 Gene3D G3DSA:1.10.10.10 2 94 4.1E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c25230 32c1788bd56673f9f1924d596f63b482 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.8E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c25230 32c1788bd56673f9f1924d596f63b482 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.8E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c25230 32c1788bd56673f9f1924d596f63b482 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.8E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c25230 32c1788bd56673f9f1924d596f63b482 302 Pfam PF03466 LysR substrate binding domain 89 298 3.2E-36 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c25230 32c1788bd56673f9f1924d596f63b482 302 Gene3D G3DSA:3.40.190.10 167 273 4.9E-47 T 12-10-2018 MIM_c25230 32c1788bd56673f9f1924d596f63b482 302 SUPERFAMILY SSF53850 90 299 2.78E-32 T 12-10-2018 MIM_c25230 32c1788bd56673f9f1924d596f63b482 302 SUPERFAMILY SSF46785 3 82 2.73E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c25230 32c1788bd56673f9f1924d596f63b482 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.6E-22 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c00110 2785669af2e08f0a197524c1d0e1915c 367 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 351 42.702 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MIM_c00110 2785669af2e08f0a197524c1d0e1915c 367 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 293 321 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MIM_c00110 2785669af2e08f0a197524c1d0e1915c 367 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 5 350 5.4E-113 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MIM_c00110 2785669af2e08f0a197524c1d0e1915c 367 Pfam PF07478 D-ala D-ala ligase C-terminus 147 348 4.4E-78 T 12-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MIM_c00110 2785669af2e08f0a197524c1d0e1915c 367 Gene3D G3DSA:3.40.50.20 2 128 6.2E-42 T 12-10-2018 MIM_c00110 2785669af2e08f0a197524c1d0e1915c 367 SUPERFAMILY SSF56059 140 354 2.3E-61 T 12-10-2018 MIM_c00110 2785669af2e08f0a197524c1d0e1915c 367 PIRSF PIRSF039102 1 359 8.1E-132 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MIM_c00110 2785669af2e08f0a197524c1d0e1915c 367 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 107 118 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MIM_c00110 2785669af2e08f0a197524c1d0e1915c 367 Gene3D G3DSA:3.30.1490.20 155 224 4.3E-88 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MIM_c00110 2785669af2e08f0a197524c1d0e1915c 367 SUPERFAMILY SSF52440 3 139 1.63E-35 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MIM_c00110 2785669af2e08f0a197524c1d0e1915c 367 Gene3D G3DSA:3.30.470.20 129 353 4.3E-88 T 12-10-2018 MIM_c00110 2785669af2e08f0a197524c1d0e1915c 367 Pfam PF01820 D-ala D-ala ligase N-terminus 6 130 2.3E-29 T 12-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MIM_c38730 775054f93bc660c8059c857da3a19248 295 SUPERFAMILY SSF52540 22 238 3.04E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c38730 775054f93bc660c8059c857da3a19248 295 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c38730 775054f93bc660c8059c857da3a19248 295 SMART SM00382 50 231 1.3E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c38730 775054f93bc660c8059c857da3a19248 295 Gene3D G3DSA:3.40.50.300 19 292 2.4E-63 T 12-10-2018 MIM_c38730 775054f93bc660c8059c857da3a19248 295 Pfam PF00005 ABC transporter 42 183 1.4E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c16640 6fe5e95adba8e8843b82097d24903a9a 152 SUPERFAMILY SSF54631 16 127 4.17E-28 T 12-10-2018 MIM_c16640 6fe5e95adba8e8843b82097d24903a9a 152 Gene3D G3DSA:3.10.580.10 1 148 2.6E-33 T 12-10-2018 MIM_c16640 6fe5e95adba8e8843b82097d24903a9a 152 SMART SM00116 79 126 9.4E-4 T 12-10-2018 IPR000644 CBS domain MIM_c16640 6fe5e95adba8e8843b82097d24903a9a 152 SMART SM00116 14 61 1.3E-4 T 12-10-2018 IPR000644 CBS domain MIM_c16640 6fe5e95adba8e8843b82097d24903a9a 152 Pfam PF00571 CBS domain 73 126 3.2E-7 T 12-10-2018 IPR000644 CBS domain MIM_c16640 6fe5e95adba8e8843b82097d24903a9a 152 Pfam PF00571 CBS domain 16 61 1.2E-7 T 12-10-2018 IPR000644 CBS domain MIM_c09480 33047462e2c067e532dae66134986efc 457 SUPERFAMILY SSF55874 290 456 3.93E-41 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c09480 33047462e2c067e532dae66134986efc 457 Gene3D G3DSA:3.30.565.10 306 457 1.9E-39 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c09480 33047462e2c067e532dae66134986efc 457 SMART SM00387 346 457 4.3E-35 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c09480 33047462e2c067e532dae66134986efc 457 SMART SM00388 236 300 2.0E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MIM_c09480 33047462e2c067e532dae66134986efc 457 Gene3D G3DSA:1.10.287.130 180 295 2.6E-26 T 12-10-2018 MIM_c09480 33047462e2c067e532dae66134986efc 457 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 346 455 2.8E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c09480 33047462e2c067e532dae66134986efc 457 SUPERFAMILY SSF47384 219 300 8.83E-16 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MIM_c09480 33047462e2c067e532dae66134986efc 457 SUPERFAMILY SSF158472 183 232 9.15E-9 T 12-10-2018 MIM_c09480 33047462e2c067e532dae66134986efc 457 Pfam PF00512 His Kinase A (phospho-acceptor) domain 237 300 2.4E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MIM_c09480 33047462e2c067e532dae66134986efc 457 Pfam PF00672 HAMP domain 183 231 6.4E-11 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MIM_c09480 33047462e2c067e532dae66134986efc 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 397 3.3E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c09480 33047462e2c067e532dae66134986efc 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 436 3.3E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c09480 33047462e2c067e532dae66134986efc 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 411 3.3E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c09480 33047462e2c067e532dae66134986efc 457 SMART SM00304 183 235 3.5E-12 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MIM_c24790 03200ee8b6cc3e12963dccfdcf69d0f2 421 Pfam PF01546 Peptidase family M20/M25/M40 76 366 9.1E-23 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 MIM_c24790 03200ee8b6cc3e12963dccfdcf69d0f2 421 Pfam PF07687 Peptidase dimerisation domain 200 287 1.1E-6 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain MIM_c24790 03200ee8b6cc3e12963dccfdcf69d0f2 421 Gene3D G3DSA:3.40.630.10 21 392 1.1E-113 T 12-10-2018 MIM_c24790 03200ee8b6cc3e12963dccfdcf69d0f2 421 SUPERFAMILY SSF53187 7 415 4.92E-77 T 12-10-2018 MIM_c24790 03200ee8b6cc3e12963dccfdcf69d0f2 421 PIRSF PIRSF005962 3 416 1.8E-101 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 MIM_c24790 03200ee8b6cc3e12963dccfdcf69d0f2 421 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 23 370 4.1E-82 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 MIM_c24790 03200ee8b6cc3e12963dccfdcf69d0f2 421 Gene3D G3DSA:3.30.70.360 195 311 1.1E-113 T 12-10-2018 MIM_c24790 03200ee8b6cc3e12963dccfdcf69d0f2 421 SUPERFAMILY SSF55031 199 300 1.7E-23 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain MIM_c07480 d05264cdff5df87cacc64edafe41c5aa 156 Pfam PF00430 ATP synthase B/B' CF(0) 6 136 6.9E-27 T 12-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MIM_c07480 d05264cdff5df87cacc64edafe41c5aa 156 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 138 11.469 T 12-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MIM_c07480 d05264cdff5df87cacc64edafe41c5aa 156 Gene3D G3DSA:1.20.5.620 65 122 1.3E-11 T 12-10-2018 MIM_c07480 d05264cdff5df87cacc64edafe41c5aa 156 SUPERFAMILY SSF81573 66 121 5.49E-9 T 12-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily MIM_c07480 d05264cdff5df87cacc64edafe41c5aa 156 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 10 155 9.1E-39 T 12-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 MIM_c39220 f91d65ac8084ca284a1be87b3fa6c8c0 477 Gene3D G3DSA:3.40.605.10 11 472 3.1E-166 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c39220 f91d65ac8084ca284a1be87b3fa6c8c0 477 Gene3D G3DSA:3.40.309.10 255 444 3.1E-166 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MIM_c39220 f91d65ac8084ca284a1be87b3fa6c8c0 477 Pfam PF00171 Aldehyde dehydrogenase family 19 473 8.9E-159 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c39220 f91d65ac8084ca284a1be87b3fa6c8c0 477 SUPERFAMILY SSF53720 5 475 3.14E-163 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c28310 fdea2fa541cdd0915b60ff3850df8393 303 Pfam PF00701 Dihydrodipicolinate synthetase family 12 299 7.1E-54 T 12-10-2018 IPR002220 DapA-like GO:0016829 MIM_c28310 fdea2fa541cdd0915b60ff3850df8393 303 PIRSF PIRSF001365 6 303 9.1E-57 T 12-10-2018 IPR002220 DapA-like GO:0016829 MIM_c28310 fdea2fa541cdd0915b60ff3850df8393 303 SUPERFAMILY SSF51569 12 300 1.03E-67 T 12-10-2018 MIM_c28310 fdea2fa541cdd0915b60ff3850df8393 303 Hamap MF_00694 Probable 5-dehydro-4-deoxyglucarate dehydratase. 10 301 44.182 T 12-10-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 MIM_c28310 fdea2fa541cdd0915b60ff3850df8393 303 Gene3D G3DSA:3.20.20.70 1 302 1.4E-97 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c28310 fdea2fa541cdd0915b60ff3850df8393 303 SMART SM01130 10 301 2.2E-79 T 12-10-2018 IPR002220 DapA-like GO:0016829 MIM_c28310 fdea2fa541cdd0915b60ff3850df8393 303 TIGRFAM TIGR03249 KdgD: 5-dehydro-4-deoxyglucarate dehydratase 3 299 8.4E-133 T 12-10-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 MIM_c29060 7512b3d10bd03d475c42977e5993d2f8 152 Pfam PF01475 Ferric uptake regulator family 10 129 2.1E-41 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 MIM_c29060 7512b3d10bd03d475c42977e5993d2f8 152 Gene3D G3DSA:1.10.10.10 1 83 3.9E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c29060 7512b3d10bd03d475c42977e5993d2f8 152 Gene3D G3DSA:3.30.1490.190 85 140 3.9E-18 T 12-10-2018 MIM_c29060 7512b3d10bd03d475c42977e5993d2f8 152 SUPERFAMILY SSF46785 6 133 1.25E-39 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c22370 458ccd271343eb625fae6a68762e45dd 130 SUPERFAMILY SSF117856 6 128 2.88E-16 T 12-10-2018 MIM_c22370 458ccd271343eb625fae6a68762e45dd 130 Gene3D G3DSA:3.30.1330.80 5 130 5.8E-17 T 12-10-2018 MIM_c22370 458ccd271343eb625fae6a68762e45dd 130 Pfam PF03479 Domain of unknown function (DUF296) 17 128 3.7E-13 T 12-10-2018 IPR005175 PPC domain MIM_c15280 1197f38cff9e08461a72d66558ccc5d2 246 Pfam PF01227 GTP cyclohydrolase I 64 243 5.0E-54 T 12-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MIM_c15280 1197f38cff9e08461a72d66558ccc5d2 246 SUPERFAMILY SSF55620 28 244 4.3E-65 T 12-10-2018 MIM_c15280 1197f38cff9e08461a72d66558ccc5d2 246 Gene3D G3DSA:3.30.1130.10 110 246 5.2E-43 T 12-10-2018 MIM_c15280 1197f38cff9e08461a72d66558ccc5d2 246 Gene3D G3DSA:1.10.286.10 32 109 1.5E-7 T 12-10-2018 MIM_c06780 1b76ee8f32f20a9e471457e9c453bf9a 214 Pfam PF03099 Biotin/lipoate A/B protein ligase family 55 163 2.4E-7 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 MIM_c06780 1b76ee8f32f20a9e471457e9c453bf9a 214 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 25 202 5.3E-54 T 12-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MIM_c06780 1b76ee8f32f20a9e471457e9c453bf9a 214 Hamap MF_00013 Octanoyltransferase [lipB]. 2 210 37.109 T 12-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MIM_c06780 1b76ee8f32f20a9e471457e9c453bf9a 214 PIRSF PIRSF016262 1 213 1.4E-59 T 12-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MIM_c06780 1b76ee8f32f20a9e471457e9c453bf9a 214 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 73 127 1.0E-14 T 12-10-2018 MIM_c06780 1b76ee8f32f20a9e471457e9c453bf9a 214 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 69 84 - T 12-10-2018 IPR020605 Octanoyltransferase, conserved site GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 MIM_c06780 1b76ee8f32f20a9e471457e9c453bf9a 214 Gene3D G3DSA:3.30.930.10 1 207 5.4E-62 T 12-10-2018 MIM_c06780 1b76ee8f32f20a9e471457e9c453bf9a 214 SUPERFAMILY SSF55681 5 208 2.07E-62 T 12-10-2018 MIM_c33860 64634b467908273eea6bb3d6f61b2468 324 SUPERFAMILY SSF53850 117 278 3.26E-12 T 12-10-2018 MIM_c33860 64634b467908273eea6bb3d6f61b2468 324 PIRSF PIRSF017082 1 323 2.6E-63 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c33860 64634b467908273eea6bb3d6f61b2468 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 314 6.5E-57 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c33860 64634b467908273eea6bb3d6f61b2468 324 Gene3D G3DSA:3.40.190.10 129 249 5.6E-83 T 12-10-2018 MIM_c33860 64634b467908273eea6bb3d6f61b2468 324 Gene3D G3DSA:3.40.190.150 31 314 5.6E-83 T 12-10-2018 MIM_c22640 cc6c686ba65d636d15153d3b8938374c 271 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c22640 cc6c686ba65d636d15153d3b8938374c 271 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 222 244 6.9E-8 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal MIM_c22640 cc6c686ba65d636d15153d3b8938374c 271 Gene3D G3DSA:3.40.50.300 1 253 4.8E-62 T 12-10-2018 MIM_c22640 cc6c686ba65d636d15153d3b8938374c 271 SMART SM00382 28 222 7.1E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c22640 cc6c686ba65d636d15153d3b8938374c 271 Pfam PF00005 ABC transporter 20 173 2.9E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c22640 cc6c686ba65d636d15153d3b8938374c 271 SUPERFAMILY SSF52540 3 244 3.09E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c39900 3b9c7f2431f052473d7f682049883a1b 392 Pfam PF01266 FAD dependent oxidoreductase 6 361 4.5E-46 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MIM_c39900 3b9c7f2431f052473d7f682049883a1b 392 Gene3D G3DSA:3.50.50.60 5 362 3.4E-93 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c39900 3b9c7f2431f052473d7f682049883a1b 392 Gene3D G3DSA:3.30.9.10 94 320 3.4E-93 T 12-10-2018 MIM_c39900 3b9c7f2431f052473d7f682049883a1b 392 SUPERFAMILY SSF51905 5 387 6.69E-40 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c04020 830d352e28783dd06ba3b20288a22ad3 316 Gene3D G3DSA:1.10.10.10 3 89 2.4E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c04020 830d352e28783dd06ba3b20288a22ad3 316 SUPERFAMILY SSF53850 91 300 2.64E-40 T 12-10-2018 MIM_c04020 830d352e28783dd06ba3b20288a22ad3 316 SUPERFAMILY SSF46785 2 112 2.9E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c04020 830d352e28783dd06ba3b20288a22ad3 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 4.9E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c04020 830d352e28783dd06ba3b20288a22ad3 316 Pfam PF03466 LysR substrate binding domain 89 296 2.1E-36 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c04020 830d352e28783dd06ba3b20288a22ad3 316 Gene3D G3DSA:3.40.190.290 92 297 8.2E-56 T 12-10-2018 MIM_c02150 c5b62afda60fceb2cf075ecc0abb6dd2 410 SUPERFAMILY SSF103473 15 406 1.7E-59 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c02150 c5b62afda60fceb2cf075ecc0abb6dd2 410 Gene3D G3DSA:1.20.1250.20 19 204 1.9E-23 T 12-10-2018 MIM_c02150 c5b62afda60fceb2cf075ecc0abb6dd2 410 Gene3D G3DSA:1.20.1250.20 219 405 2.4E-22 T 12-10-2018 MIM_c02150 c5b62afda60fceb2cf075ecc0abb6dd2 410 Pfam PF07690 Major Facilitator Superfamily 30 355 8.4E-38 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c06980 7ff886ddadf30c82ecccae63a0a46552 316 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 143 251 8.3E-11 T 12-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 MIM_c06980 7ff886ddadf30c82ecccae63a0a46552 316 Gene3D G3DSA:3.40.50.2000 132 292 6.8E-19 T 12-10-2018 MIM_c06980 7ff886ddadf30c82ecccae63a0a46552 316 SUPERFAMILY SSF53756 6 290 5.96E-27 T 12-10-2018 MIM_c22720 82672246e30ca342aab911ca05e3f13f 304 Gene3D G3DSA:3.40.50.1100 11 297 4.9E-102 T 12-10-2018 MIM_c22720 82672246e30ca342aab911ca05e3f13f 304 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 301 7.1E-111 T 12-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MIM_c22720 82672246e30ca342aab911ca05e3f13f 304 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 38 56 - T 12-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 MIM_c22720 82672246e30ca342aab911ca05e3f13f 304 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 290 1.4E-63 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MIM_c22720 82672246e30ca342aab911ca05e3f13f 304 TIGRFAM TIGR01138 cysM: cysteine synthase B 7 301 6.4E-132 T 12-10-2018 IPR005858 Cysteine synthase CysM GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MIM_c22720 82672246e30ca342aab911ca05e3f13f 304 Gene3D G3DSA:3.40.50.1100 43 149 4.9E-102 T 12-10-2018 MIM_c22720 82672246e30ca342aab911ca05e3f13f 304 SUPERFAMILY SSF53686 3 298 2.36E-85 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MIM_c07270 7f2ad08ed983cdbcb0240cb02bcd0a10 154 Gene3D G3DSA:3.40.1280.10 1 153 2.8E-60 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MIM_c07270 7f2ad08ed983cdbcb0240cb02bcd0a10 154 PIRSF PIRSF029256 1 153 7.0E-60 T 12-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 MIM_c07270 7f2ad08ed983cdbcb0240cb02bcd0a10 154 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 151 32.32 T 12-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 MIM_c07270 7f2ad08ed983cdbcb0240cb02bcd0a10 154 SUPERFAMILY SSF75217 1 150 9.16E-42 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases MIM_c07270 7f2ad08ed983cdbcb0240cb02bcd0a10 154 Pfam PF00588 SpoU rRNA Methylase family 2 142 1.6E-30 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MIM_c26460 3c616585004b397648951fb7139a1b7f 321 SUPERFAMILY SSF53850 123 279 8.51E-12 T 12-10-2018 MIM_c26460 3c616585004b397648951fb7139a1b7f 321 Gene3D G3DSA:3.40.190.10 125 248 2.8E-96 T 12-10-2018 MIM_c26460 3c616585004b397648951fb7139a1b7f 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 316 4.7E-72 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c26460 3c616585004b397648951fb7139a1b7f 321 Gene3D G3DSA:3.40.190.150 26 313 2.8E-96 T 12-10-2018 MIM_c26460 3c616585004b397648951fb7139a1b7f 321 PIRSF PIRSF017082 1 321 3.2E-72 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c31240 474627940b6daabc0b33dda0e93b1153 397 SUPERFAMILY SSF103473 9 394 7.98E-32 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c31240 474627940b6daabc0b33dda0e93b1153 397 Pfam PF07690 Major Facilitator Superfamily 22 348 1.1E-10 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c31240 474627940b6daabc0b33dda0e93b1153 397 Gene3D G3DSA:1.20.1250.20 206 397 1.5E-11 T 12-10-2018 MIM_c31240 474627940b6daabc0b33dda0e93b1153 397 Gene3D G3DSA:1.20.1250.20 5 199 6.9E-10 T 12-10-2018 MIM_c11170 1258fd491b10ea6a97b6510d3030d50e 280 Pfam PF13714 Phosphoenolpyruvate phosphomutase 15 251 1.5E-64 T 12-10-2018 MIM_c11170 1258fd491b10ea6a97b6510d3030d50e 280 Gene3D G3DSA:3.20.20.60 1 233 8.3E-59 T 12-10-2018 MIM_c11170 1258fd491b10ea6a97b6510d3030d50e 280 SUPERFAMILY SSF51621 10 261 2.2E-53 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MIM_c17790 8bf8bcb0a9e8c6190a83f523ca2d3d6e 305 SUPERFAMILY SSF51197 32 290 6.96E-65 T 12-10-2018 MIM_c17790 8bf8bcb0a9e8c6190a83f523ca2d3d6e 305 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 43 258 6.2E-34 T 12-10-2018 IPR008775 Phytanoyl-CoA dioxygenase MIM_c17790 8bf8bcb0a9e8c6190a83f523ca2d3d6e 305 Gene3D G3DSA:2.60.120.620 1 300 6.3E-112 T 12-10-2018 MIM_c17790 8bf8bcb0a9e8c6190a83f523ca2d3d6e 305 TIGRFAM TIGR02408 ectoine_ThpD: ectoine hydroxylase 19 292 8.7E-137 T 12-10-2018 IPR012774 Ectoine dioxygenase GO:0016706|GO:0055114 MIM_c03010 96d589bcbea0ff2e373dc5af4dc8cc66 109 Pfam PF07411 Domain of unknown function (DUF1508) 12 56 4.0E-16 T 12-10-2018 IPR010879 Domain of unknown function DUF1508 MIM_c03010 96d589bcbea0ff2e373dc5af4dc8cc66 109 Pfam PF07411 Domain of unknown function (DUF1508) 62 108 2.0E-15 T 12-10-2018 IPR010879 Domain of unknown function DUF1508 MIM_c03010 96d589bcbea0ff2e373dc5af4dc8cc66 109 Gene3D G3DSA:2.30.29.80 1 109 2.2E-36 T 12-10-2018 MIM_c03010 96d589bcbea0ff2e373dc5af4dc8cc66 109 SUPERFAMILY SSF160113 3 59 1.02E-14 T 12-10-2018 IPR036913 YegP-like superfamily MIM_c03010 96d589bcbea0ff2e373dc5af4dc8cc66 109 SUPERFAMILY SSF160113 55 108 1.83E-12 T 12-10-2018 IPR036913 YegP-like superfamily MIM_c39360 c78cf43f3f8db1946cc8d8bd1bfae4c3 325 Gene3D G3DSA:3.40.190.150 27 315 7.5E-106 T 12-10-2018 MIM_c39360 c78cf43f3f8db1946cc8d8bd1bfae4c3 325 SUPERFAMILY SSF53850 112 284 7.97E-9 T 12-10-2018 MIM_c39360 c78cf43f3f8db1946cc8d8bd1bfae4c3 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 321 1.5E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c39360 c78cf43f3f8db1946cc8d8bd1bfae4c3 325 Gene3D G3DSA:3.40.190.10 124 247 7.5E-106 T 12-10-2018 MIM_c39360 c78cf43f3f8db1946cc8d8bd1bfae4c3 325 PIRSF PIRSF017082 3 325 3.7E-82 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c30510 0f2aac397d7016ef92b0a9712cd57d16 427 SUPERFAMILY SSF56796 6 407 5.89E-92 T 12-10-2018 MIM_c30510 0f2aac397d7016ef92b0a9712cd57d16 427 Pfam PF00465 Iron-containing alcohol dehydrogenase 12 391 1.7E-95 T 12-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 MIM_c30510 0f2aac397d7016ef92b0a9712cd57d16 427 Gene3D G3DSA:1.20.1090.10 192 410 2.6E-49 T 12-10-2018 MIM_c30510 0f2aac397d7016ef92b0a9712cd57d16 427 Gene3D G3DSA:3.40.50.1970 1 191 9.1E-42 T 12-10-2018 MIM_c32230 df58802615b850f553d96c136ab11d27 504 SUPERFAMILY SSF52540 297 503 5.07E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c32230 df58802615b850f553d96c136ab11d27 504 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 228 503 56.106 T 12-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 MIM_c32230 df58802615b850f553d96c136ab11d27 504 SMART SM00382 298 476 6.2E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c32230 df58802615b850f553d96c136ab11d27 504 Pfam PF02881 SRP54-type protein, helical bundle domain 218 279 3.2E-11 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MIM_c32230 df58802615b850f553d96c136ab11d27 504 Pfam PF00448 SRP54-type protein, GTPase domain 300 502 5.4E-65 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MIM_c32230 df58802615b850f553d96c136ab11d27 504 SMART SM00962 299 503 2.3E-102 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MIM_c32230 df58802615b850f553d96c136ab11d27 504 SUPERFAMILY SSF47364 204 279 1.57E-17 T 12-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 MIM_c32230 df58802615b850f553d96c136ab11d27 504 SMART SM00963 209 285 2.5E-17 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MIM_c32230 df58802615b850f553d96c136ab11d27 504 Gene3D G3DSA:3.40.50.300 299 491 4.1E-101 T 12-10-2018 MIM_c32230 df58802615b850f553d96c136ab11d27 504 Gene3D G3DSA:1.20.120.140 207 501 4.1E-101 T 12-10-2018 MIM_c32230 df58802615b850f553d96c136ab11d27 504 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 228 501 1.5E-93 T 12-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 MIM_c14710 1577cfb67d834f1337e534cf654d527c 233 Pfam PF00196 Bacterial regulatory proteins, luxR family 171 224 2.4E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MIM_c14710 1577cfb67d834f1337e534cf654d527c 233 Gene3D G3DSA:1.10.10.10 168 233 8.7E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c14710 1577cfb67d834f1337e534cf654d527c 233 SMART SM00421 168 225 5.1E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MIM_c14710 1577cfb67d834f1337e534cf654d527c 233 Gene3D G3DSA:3.30.450.80 5 161 1.4E-7 T 12-10-2018 IPR036693 Transcription factor LuxR-like, autoinducer-binding domain superfamily MIM_c14710 1577cfb67d834f1337e534cf654d527c 233 SUPERFAMILY SSF46894 156 231 2.48E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MIM_c14710 1577cfb67d834f1337e534cf654d527c 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 201 213 2.0E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MIM_c14710 1577cfb67d834f1337e534cf654d527c 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 201 2.0E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MIM_c14710 1577cfb67d834f1337e534cf654d527c 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 185 2.0E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MIM_c14710 1577cfb67d834f1337e534cf654d527c 233 SUPERFAMILY SSF75516 8 154 3.4E-6 T 12-10-2018 IPR036693 Transcription factor LuxR-like, autoinducer-binding domain superfamily MIM_c28470 fbcdb8edb13de3401826382f47cf714d 167 Gene3D G3DSA:3.90.1170.40 1 149 1.4E-47 T 12-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 MIM_c28470 fbcdb8edb13de3401826382f47cf714d 167 Pfam PF02391 MoaE protein 5 119 1.7E-34 T 12-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 MIM_c28470 fbcdb8edb13de3401826382f47cf714d 167 SUPERFAMILY SSF54690 2 149 6.93E-47 T 12-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 MIM_c08340 11877956e3089f127e4fd67d1c0759a2 437 PIRSF PIRSF006066 5 437 5.2E-86 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 MIM_c08340 11877956e3089f127e4fd67d1c0759a2 437 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 21 431 3.9E-101 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 MIM_c08340 11877956e3089f127e4fd67d1c0759a2 437 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 12 425 4.2E-89 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit MIM_c33550 594ecd6807fc2b576921e77f6e9ec13b 241 SUPERFAMILY SSF48008 97 229 2.56E-25 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c33550 594ecd6807fc2b576921e77f6e9ec13b 241 Pfam PF07729 FCD domain 100 221 1.1E-23 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c33550 594ecd6807fc2b576921e77f6e9ec13b 241 SMART SM00895 100 222 3.3E-21 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c33550 594ecd6807fc2b576921e77f6e9ec13b 241 SUPERFAMILY SSF46785 25 94 7.88E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c33550 594ecd6807fc2b576921e77f6e9ec13b 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 32 90 7.0E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c33550 594ecd6807fc2b576921e77f6e9ec13b 241 SMART SM00345 32 90 2.5E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c33550 594ecd6807fc2b576921e77f6e9ec13b 241 Gene3D G3DSA:1.20.120.530 93 231 1.9E-26 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c33550 594ecd6807fc2b576921e77f6e9ec13b 241 Gene3D G3DSA:1.10.10.10 28 91 3.7E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c26440 9b3d9917750334d4fa4ab1f0882b4870 532 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 75 97 - T 12-10-2018 IPR023765 Solute-binding protein family 5, conserved site MIM_c26440 9b3d9917750334d4fa4ab1f0882b4870 532 Gene3D G3DSA:3.10.105.10 290 507 1.3E-167 T 12-10-2018 MIM_c26440 9b3d9917750334d4fa4ab1f0882b4870 532 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 69 451 2.1E-99 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain MIM_c26440 9b3d9917750334d4fa4ab1f0882b4870 532 SUPERFAMILY SSF53850 25 530 2.4E-147 T 12-10-2018 MIM_c26440 9b3d9917750334d4fa4ab1f0882b4870 532 Gene3D G3DSA:3.40.190.10 207 520 1.3E-167 T 12-10-2018 MIM_c26440 9b3d9917750334d4fa4ab1f0882b4870 532 Gene3D G3DSA:3.90.76.10 46 206 1.3E-167 T 12-10-2018 MIM_c26440 9b3d9917750334d4fa4ab1f0882b4870 532 PIRSF PIRSF002741 9 531 2.8E-113 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MIM_c25160 a57cd92d2cc5d57859293edb81e29b6c 504 Gene3D G3DSA:3.40.30.120 374 494 1.4E-14 T 12-10-2018 MIM_c25160 a57cd92d2cc5d57859293edb81e29b6c 504 Gene3D G3DSA:3.30.70.2450 188 272 5.7E-104 T 12-10-2018 MIM_c25160 a57cd92d2cc5d57859293edb81e29b6c 504 Gene3D G3DSA:3.50.50.60 8 345 5.7E-104 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c25160 a57cd92d2cc5d57859293edb81e29b6c 504 Pfam PF01494 FAD binding domain 7 345 4.0E-84 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 MIM_c25160 a57cd92d2cc5d57859293edb81e29b6c 504 SUPERFAMILY SSF51905 7 353 9.13E-62 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c25160 a57cd92d2cc5d57859293edb81e29b6c 504 SUPERFAMILY SSF52833 384 496 5.37E-12 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c25160 a57cd92d2cc5d57859293edb81e29b6c 504 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 3.5E-38 T 12-10-2018 MIM_c25160 a57cd92d2cc5d57859293edb81e29b6c 504 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 3.5E-38 T 12-10-2018 MIM_c25160 a57cd92d2cc5d57859293edb81e29b6c 504 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 333 349 3.5E-38 T 12-10-2018 MIM_c25160 a57cd92d2cc5d57859293edb81e29b6c 504 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 159 174 3.5E-38 T 12-10-2018 MIM_c25160 a57cd92d2cc5d57859293edb81e29b6c 504 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 3.5E-38 T 12-10-2018 MIM_c38820 b440524df9e93defeb6a2fa1666e80a1 361 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 341 6.6E-89 T 12-10-2018 IPR016040 NAD(P)-binding domain MIM_c38820 b440524df9e93defeb6a2fa1666e80a1 361 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 4 355 6.9E-140 T 12-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 MIM_c38820 b440524df9e93defeb6a2fa1666e80a1 361 Gene3D G3DSA:3.90.25.10 206 350 5.5E-116 T 12-10-2018 MIM_c38820 b440524df9e93defeb6a2fa1666e80a1 361 SUPERFAMILY SSF51735 3 354 8.44E-84 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c38820 b440524df9e93defeb6a2fa1666e80a1 361 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c38820 b440524df9e93defeb6a2fa1666e80a1 361 Gene3D G3DSA:3.40.50.720 4 341 5.5E-116 T 12-10-2018 MIM_c33430 0098af5ea798f9a4d07458cd2669d747 216 SMART SM01144 11 205 9.0E-63 T 12-10-2018 IPR005636 DTW MIM_c33430 0098af5ea798f9a4d07458cd2669d747 216 Pfam PF03942 DTW domain 12 200 8.9E-46 T 12-10-2018 IPR005636 DTW MIM_c07180 febee32338e629c969ba5fd2ffc90d7d 321 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 2 319 33.21 T 12-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 MIM_c07180 febee32338e629c969ba5fd2ffc90d7d 321 Gene3D G3DSA:3.40.50.170 1 214 1.1E-71 T 12-10-2018 MIM_c07180 febee32338e629c969ba5fd2ffc90d7d 321 Gene3D G3DSA:3.10.25.10 215 319 5.3E-19 T 12-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MIM_c07180 febee32338e629c969ba5fd2ffc90d7d 321 SUPERFAMILY SSF50486 213 317 2.35E-20 T 12-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 MIM_c07180 febee32338e629c969ba5fd2ffc90d7d 321 Pfam PF00551 Formyl transferase 4 187 8.7E-37 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MIM_c07180 febee32338e629c969ba5fd2ffc90d7d 321 Pfam PF02911 Formyl transferase, C-terminal domain 212 315 1.8E-17 T 12-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MIM_c07180 febee32338e629c969ba5fd2ffc90d7d 321 SUPERFAMILY SSF53328 3 212 5.76E-56 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MIM_c07180 febee32338e629c969ba5fd2ffc90d7d 321 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 2 317 3.8E-78 T 12-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 MIM_c38060 ba46ad774619d7b945559e8e88209c19 161 SUPERFAMILY SSF141452 2 159 4.97E-48 T 12-10-2018 IPR036624 Hcp1-like superfamily MIM_c38060 ba46ad774619d7b945559e8e88209c19 161 Pfam PF05638 Type VI secretion system effector, Hcp 6 135 1.2E-36 T 12-10-2018 IPR008514 Type VI secretion system effector, Hcp MIM_c38060 ba46ad774619d7b945559e8e88209c19 161 Gene3D G3DSA:2.30.110.20 2 159 7.1E-55 T 12-10-2018 IPR036624 Hcp1-like superfamily MIM_c20340 e2b425e6fd64ed099286b3d04f065712 308 SUPERFAMILY SSF63829 10 304 6.1E-55 T 12-10-2018 MIM_c20340 e2b425e6fd64ed099286b3d04f065712 308 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 229 246 1.1E-5 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MIM_c20340 e2b425e6fd64ed099286b3d04f065712 308 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 160 182 1.1E-5 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MIM_c20340 e2b425e6fd64ed099286b3d04f065712 308 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 271 289 1.1E-5 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MIM_c20340 e2b425e6fd64ed099286b3d04f065712 308 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 17 288 1.7E-51 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region MIM_c20340 e2b425e6fd64ed099286b3d04f065712 308 Gene3D G3DSA:2.120.10.30 4 305 5.1E-59 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MIM_c21210 0dedc9586588f98b74c0f67462f3d54e 193 SUPERFAMILY SSF55469 3 187 8.64E-33 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MIM_c21210 0dedc9586588f98b74c0f67462f3d54e 193 Gene3D G3DSA:3.40.109.10 5 167 2.2E-32 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MIM_c21210 0dedc9586588f98b74c0f67462f3d54e 193 Pfam PF00881 Nitroreductase family 10 166 1.4E-22 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MIM_c21210 0dedc9586588f98b74c0f67462f3d54e 193 PIRSF PIRSF000232 1 190 2.2E-45 T 12-10-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like MIM_c32090 27bf92d83d6da9e236e3aabbfbc99a50 183 SUPERFAMILY SSF101307 32 179 3.53E-35 T 12-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 MIM_c32090 27bf92d83d6da9e236e3aabbfbc99a50 183 PIRSF PIRSF006162 26 183 8.9E-41 T 12-10-2018 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 MIM_c32090 27bf92d83d6da9e236e3aabbfbc99a50 183 Pfam PF04608 Phosphatidylglycerophosphatase A 36 178 6.0E-47 T 12-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 MIM_c30630 b8c7d7125b1e886614d58b46a82c7921 610 SUPERFAMILY SSF161098 416 600 3.4E-37 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c30630 b8c7d7125b1e886614d58b46a82c7921 610 Gene3D G3DSA:3.40.190.10 25 312 2.8E-56 T 12-10-2018 MIM_c30630 b8c7d7125b1e886614d58b46a82c7921 610 SUPERFAMILY SSF53850 17 316 5.97E-71 T 12-10-2018 MIM_c30630 b8c7d7125b1e886614d58b46a82c7921 610 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 24 301 1.1E-55 T 12-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 MIM_c30630 b8c7d7125b1e886614d58b46a82c7921 610 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 439 603 5.0E-25 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c30630 b8c7d7125b1e886614d58b46a82c7921 610 Gene3D G3DSA:3.40.190.100 107 245 2.8E-56 T 12-10-2018 MIM_c30630 b8c7d7125b1e886614d58b46a82c7921 610 Gene3D G3DSA:1.10.3720.10 413 608 3.9E-35 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c39130 7cf5e21c7350bb4b4d07343b938bc306 374 Pfam PF08402 TOBE domain 288 364 1.4E-16 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 MIM_c39130 7cf5e21c7350bb4b4d07343b938bc306 374 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c39130 7cf5e21c7350bb4b4d07343b938bc306 374 Gene3D G3DSA:2.40.50.140 250 290 3.5E-8 T 12-10-2018 MIM_c39130 7cf5e21c7350bb4b4d07343b938bc306 374 SUPERFAMILY SSF52540 12 252 2.99E-87 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c39130 7cf5e21c7350bb4b4d07343b938bc306 374 SUPERFAMILY SSF50331 246 365 3.27E-17 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MIM_c39130 7cf5e21c7350bb4b4d07343b938bc306 374 Gene3D G3DSA:3.40.50.300 2 248 1.0E-77 T 12-10-2018 MIM_c39130 7cf5e21c7350bb4b4d07343b938bc306 374 Gene3D G3DSA:2.40.50.100 291 354 3.5E-8 T 12-10-2018 MIM_c39130 7cf5e21c7350bb4b4d07343b938bc306 374 Pfam PF00005 ABC transporter 30 171 4.2E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c39130 7cf5e21c7350bb4b4d07343b938bc306 374 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 44 364 1.0E-114 T 12-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 MIM_c39130 7cf5e21c7350bb4b4d07343b938bc306 374 SMART SM00382 38 222 2.9E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c33840 10c5ecc9e6728de0f2d613b716e26200 294 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 286 1.3E-29 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MIM_c33840 10c5ecc9e6728de0f2d613b716e26200 294 Gene3D G3DSA:3.40.50.720 1 167 1.2E-42 T 12-10-2018 MIM_c33840 10c5ecc9e6728de0f2d613b716e26200 294 SUPERFAMILY SSF48179 166 289 4.42E-25 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c33840 10c5ecc9e6728de0f2d613b716e26200 294 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 160 8.6E-39 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 MIM_c33840 10c5ecc9e6728de0f2d613b716e26200 294 Gene3D G3DSA:1.10.1040.10 168 293 3.1E-27 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MIM_c33840 10c5ecc9e6728de0f2d613b716e26200 294 PIRSF PIRSF000103 1 291 8.0E-60 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 MIM_c33840 10c5ecc9e6728de0f2d613b716e26200 294 SUPERFAMILY SSF51735 1 164 1.21E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c02380 8a95ef90916b3e16f0669cc52ca38f50 297 Pfam PF00797 N-acetyltransferase 28 263 1.5E-70 T 12-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 MIM_c02380 8a95ef90916b3e16f0669cc52ca38f50 297 Gene3D G3DSA:3.30.2140.10 11 257 3.5E-88 T 12-10-2018 MIM_c02380 8a95ef90916b3e16f0669cc52ca38f50 297 SUPERFAMILY SSF54001 10 263 2.7E-79 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily MIM_c02380 8a95ef90916b3e16f0669cc52ca38f50 297 PRINTS PR01543 Arylamine N-acetyltransferase signature 28 51 3.2E-10 T 12-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 MIM_c02380 8a95ef90916b3e16f0669cc52ca38f50 297 PRINTS PR01543 Arylamine N-acetyltransferase signature 52 75 3.2E-10 T 12-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 MIM_c02380 8a95ef90916b3e16f0669cc52ca38f50 297 PRINTS PR01543 Arylamine N-acetyltransferase signature 109 134 3.2E-10 T 12-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 MIM_c02380 8a95ef90916b3e16f0669cc52ca38f50 297 PRINTS PR01543 Arylamine N-acetyltransferase signature 76 98 3.2E-10 T 12-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 MIM_c02380 8a95ef90916b3e16f0669cc52ca38f50 297 Gene3D G3DSA:2.40.128.150 92 188 3.5E-88 T 12-10-2018 MIM_c21940 e5ca41bdd53ebfb0015be48a15d590d5 195 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 16 185 31.933 T 12-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MIM_c21940 e5ca41bdd53ebfb0015be48a15d590d5 195 Gene3D G3DSA:3.10.20.80 16 90 6.2E-33 T 12-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MIM_c21940 e5ca41bdd53ebfb0015be48a15d590d5 195 Gene3D G3DSA:3.30.110.10 91 186 2.0E-36 T 12-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 MIM_c21940 e5ca41bdd53ebfb0015be48a15d590d5 195 SUPERFAMILY SSF54364 20 92 9.68E-30 T 12-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MIM_c21940 e5ca41bdd53ebfb0015be48a15d590d5 195 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 22 91 5.0E-32 T 12-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MIM_c21940 e5ca41bdd53ebfb0015be48a15d590d5 195 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 22 185 2.1E-71 T 12-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MIM_c21940 e5ca41bdd53ebfb0015be48a15d590d5 195 ProSitePatterns PS00938 Initiation factor 3 signature. 73 86 - T 12-10-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 MIM_c21940 e5ca41bdd53ebfb0015be48a15d590d5 195 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 98 183 3.3E-38 T 12-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 MIM_c21940 e5ca41bdd53ebfb0015be48a15d590d5 195 SUPERFAMILY SSF55200 97 185 1.16E-33 T 12-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 MIM_c06740 b002c27f6e84b894ca93d445015625ff 223 Pfam PF12146 Serine aminopeptidase, S33 42 131 5.8E-9 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 MIM_c06740 b002c27f6e84b894ca93d445015625ff 223 Gene3D G3DSA:3.40.50.1820 1 218 5.9E-44 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c06740 b002c27f6e84b894ca93d445015625ff 223 SUPERFAMILY SSF53474 3 212 2.49E-34 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c19400 5ec2367f8a8b017099d7043b6bd178e8 444 SUPERFAMILY SSF50156 220 318 8.41E-11 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 MIM_c19400 5ec2367f8a8b017099d7043b6bd178e8 444 Gene3D G3DSA:2.30.42.10 125 209 1.6E-9 T 12-10-2018 MIM_c19400 5ec2367f8a8b017099d7043b6bd178e8 444 Pfam PF13180 PDZ domain 131 191 9.8E-8 T 12-10-2018 IPR001478 PDZ domain GO:0005515 MIM_c19400 5ec2367f8a8b017099d7043b6bd178e8 444 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 5 442 3.5E-92 T 12-10-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 MIM_c19400 5ec2367f8a8b017099d7043b6bd178e8 444 Pfam PF02163 Peptidase family M50 7 430 1.4E-72 T 12-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 MIM_c19400 5ec2367f8a8b017099d7043b6bd178e8 444 Gene3D G3DSA:2.30.42.10 218 304 2.6E-13 T 12-10-2018 MIM_c19400 5ec2367f8a8b017099d7043b6bd178e8 444 SUPERFAMILY SSF50156 87 184 9.2E-13 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 MIM_c19400 5ec2367f8a8b017099d7043b6bd178e8 444 SMART SM00228 200 275 0.039 T 12-10-2018 IPR001478 PDZ domain GO:0005515 MIM_c19400 5ec2367f8a8b017099d7043b6bd178e8 444 SMART SM00228 108 184 0.021 T 12-10-2018 IPR001478 PDZ domain GO:0005515 MIM_c24020 cebb7d24d241c90ddc6321cbf661355b 221 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 88 183 2.1E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MIM_c24020 cebb7d24d241c90ddc6321cbf661355b 221 SUPERFAMILY SSF56784 1 215 1.58E-59 T 12-10-2018 IPR036412 HAD-like superfamily MIM_c24020 cebb7d24d241c90ddc6321cbf661355b 221 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 96 177 3.9E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MIM_c24020 cebb7d24d241c90ddc6321cbf661355b 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 183 1.1E-36 T 12-10-2018 MIM_c24020 cebb7d24d241c90ddc6321cbf661355b 221 Gene3D G3DSA:3.40.50.1000 6 204 2.3E-55 T 12-10-2018 IPR023214 HAD superfamily MIM_c24020 cebb7d24d241c90ddc6321cbf661355b 221 Gene3D G3DSA:1.10.150.240 18 83 2.3E-55 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MIM_c03050 5151e2a947beee9f258bf8bd9e38d2bc 274 SUPERFAMILY SSF51621 9 269 2.51E-92 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MIM_c03050 5151e2a947beee9f258bf8bd9e38d2bc 274 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 10 269 38.88 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MIM_c03050 5151e2a947beee9f258bf8bd9e38d2bc 274 Pfam PF02548 Ketopantoate hydroxymethyltransferase 9 264 2.7E-99 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MIM_c03050 5151e2a947beee9f258bf8bd9e38d2bc 274 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 8 269 2.1E-90 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MIM_c03050 5151e2a947beee9f258bf8bd9e38d2bc 274 PIRSF PIRSF000388 1 272 2.7E-97 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MIM_c03050 5151e2a947beee9f258bf8bd9e38d2bc 274 Gene3D G3DSA:3.20.20.60 7 274 4.3E-95 T 12-10-2018 MIM_c27640 fed6ff2de4e6d9b8fc052a3021cb584d 408 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 21 391 2.2E-104 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 MIM_c27640 fed6ff2de4e6d9b8fc052a3021cb584d 408 SUPERFAMILY SSF55031 190 303 1.7E-30 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain MIM_c27640 fed6ff2de4e6d9b8fc052a3021cb584d 408 Gene3D G3DSA:3.30.70.360 188 302 7.4E-136 T 12-10-2018 MIM_c27640 fed6ff2de4e6d9b8fc052a3021cb584d 408 Pfam PF07687 Peptidase dimerisation domain 193 265 2.9E-7 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain MIM_c27640 fed6ff2de4e6d9b8fc052a3021cb584d 408 Pfam PF01546 Peptidase family M20/M25/M40 79 365 3.4E-35 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 MIM_c27640 fed6ff2de4e6d9b8fc052a3021cb584d 408 Gene3D G3DSA:3.40.630.10 21 387 7.4E-136 T 12-10-2018 MIM_c27640 fed6ff2de4e6d9b8fc052a3021cb584d 408 SUPERFAMILY SSF53187 17 403 1.89E-85 T 12-10-2018 MIM_c27640 fed6ff2de4e6d9b8fc052a3021cb584d 408 PIRSF PIRSF005962 7 407 1.7E-126 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 MIM_c13860 6d34126de88545e5742722e5bc186606 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 313 4.9E-74 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c13860 6d34126de88545e5742722e5bc186606 320 SUPERFAMILY SSF53850 109 285 7.11E-15 T 12-10-2018 MIM_c13860 6d34126de88545e5742722e5bc186606 320 PIRSF PIRSF017082 1 319 6.6E-70 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c13860 6d34126de88545e5742722e5bc186606 320 Gene3D G3DSA:3.40.190.10 124 245 1.5E-96 T 12-10-2018 MIM_c13860 6d34126de88545e5742722e5bc186606 320 Gene3D G3DSA:3.40.190.150 26 310 1.5E-96 T 12-10-2018 MIM_c28540 8baa45f7777c3b79dc6ff64c307204cd 519 SUPERFAMILY SSF142019 97 337 6.54E-85 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c28540 8baa45f7777c3b79dc6ff64c307204cd 519 SUPERFAMILY SSF140490 424 508 6.41E-29 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c28540 8baa45f7777c3b79dc6ff64c307204cd 519 SUPERFAMILY SSF142984 340 421 9.02E-21 T 12-10-2018 MIM_c28540 8baa45f7777c3b79dc6ff64c307204cd 519 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 439 450 - T 12-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c28540 8baa45f7777c3b79dc6ff64c307204cd 519 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 145 316 6.0E-44 T 12-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c28540 8baa45f7777c3b79dc6ff64c307204cd 519 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 428 508 1.7E-31 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c28540 8baa45f7777c3b79dc6ff64c307204cd 519 SMART SM00928 426 471 2.2E-17 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c28540 8baa45f7777c3b79dc6ff64c307204cd 519 Gene3D G3DSA:1.20.1440.230 424 519 3.5E-26 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c28540 8baa45f7777c3b79dc6ff64c307204cd 519 SUPERFAMILY SSF52833 2 84 2.12E-7 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c28540 8baa45f7777c3b79dc6ff64c307204cd 519 Gene3D G3DSA:3.10.20.600 329 423 1.7E-23 T 12-10-2018 MIM_c28540 8baa45f7777c3b79dc6ff64c307204cd 519 Gene3D G3DSA:3.40.50.11540 150 328 1.6E-69 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c28540 8baa45f7777c3b79dc6ff64c307204cd 519 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 264 279 - T 12-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c37050 662fbad9d5963ae92dd756ffb7c970a7 361 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 357 41.448 T 12-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 MIM_c37050 662fbad9d5963ae92dd756ffb7c970a7 361 Gene3D G3DSA:3.30.70.1660 111 340 1.5E-97 T 12-10-2018 MIM_c37050 662fbad9d5963ae92dd756ffb7c970a7 361 Pfam PF00472 RF-1 domain 212 321 2.1E-41 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MIM_c37050 662fbad9d5963ae92dd756ffb7c970a7 361 Gene3D G3DSA:3.30.160.20 210 297 1.5E-97 T 12-10-2018 MIM_c37050 662fbad9d5963ae92dd756ffb7c970a7 361 SMART SM00937 64 178 3.2E-65 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 MIM_c37050 662fbad9d5963ae92dd756ffb7c970a7 361 SUPERFAMILY SSF75620 12 353 2.22E-136 T 12-10-2018 MIM_c37050 662fbad9d5963ae92dd756ffb7c970a7 361 Gene3D G3DSA:1.20.58.410 3 98 1.6E-6 T 12-10-2018 MIM_c37050 662fbad9d5963ae92dd756ffb7c970a7 361 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 228 244 - T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MIM_c37050 662fbad9d5963ae92dd756ffb7c970a7 361 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 356 2.4E-163 T 12-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 MIM_c37050 662fbad9d5963ae92dd756ffb7c970a7 361 Pfam PF03462 PCRF domain 13 203 4.6E-71 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 MIM_c05010 e32f5a42c3c0bdfb2bf73238ce2686c7 203 Pfam PF00043 Glutathione S-transferase, C-terminal domain 114 188 4.1E-8 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal MIM_c05010 e32f5a42c3c0bdfb2bf73238ce2686c7 203 SUPERFAMILY SSF52833 1 101 9.42E-27 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c05010 e32f5a42c3c0bdfb2bf73238ce2686c7 203 Gene3D G3DSA:1.20.1050.10 80 187 3.6E-73 T 12-10-2018 MIM_c05010 e32f5a42c3c0bdfb2bf73238ce2686c7 203 SUPERFAMILY SSF47616 73 202 1.34E-23 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MIM_c05010 e32f5a42c3c0bdfb2bf73238ce2686c7 203 Gene3D G3DSA:3.40.30.10 2 192 3.6E-73 T 12-10-2018 MIM_c05010 e32f5a42c3c0bdfb2bf73238ce2686c7 203 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 77 2.1E-18 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MIM_c09040 57076554f79bd25b51b66392109127fb 335 Gene3D G3DSA:3.30.420.40 1 320 6.9E-131 T 12-10-2018 MIM_c09040 57076554f79bd25b51b66392109127fb 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 293 319 3.1E-61 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MIM_c09040 57076554f79bd25b51b66392109127fb 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 125 144 3.1E-61 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MIM_c09040 57076554f79bd25b51b66392109127fb 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 61 84 3.1E-61 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MIM_c09040 57076554f79bd25b51b66392109127fb 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 180 200 3.1E-61 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MIM_c09040 57076554f79bd25b51b66392109127fb 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 41 59 3.1E-61 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MIM_c09040 57076554f79bd25b51b66392109127fb 335 Gene3D G3DSA:3.90.640.10 179 252 6.9E-131 T 12-10-2018 MIM_c09040 57076554f79bd25b51b66392109127fb 335 SUPERFAMILY SSF53067 1 141 9.88E-36 T 12-10-2018 MIM_c09040 57076554f79bd25b51b66392109127fb 335 SUPERFAMILY SSF53067 143 327 1.36E-49 T 12-10-2018 MIM_c09040 57076554f79bd25b51b66392109127fb 335 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 1 328 4.5E-150 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MIM_c09040 57076554f79bd25b51b66392109127fb 335 Pfam PF06723 MreB/Mbl protein 1 328 9.3E-145 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MIM_c09040 57076554f79bd25b51b66392109127fb 335 Gene3D G3DSA:3.30.420.40 147 310 6.9E-131 T 12-10-2018 MIM_24p00190 f7dfb1c52eadab77cb43ca2774821e01 140 Pfam PF01695 IstB-like ATP binding protein 1 114 6.2E-36 T 12-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 MIM_24p00190 f7dfb1c52eadab77cb43ca2774821e01 140 Gene3D G3DSA:3.40.50.300 1 130 1.5E-26 T 12-10-2018 MIM_24p00190 f7dfb1c52eadab77cb43ca2774821e01 140 SUPERFAMILY SSF52540 4 121 1.13E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c19760 9f6c9ff9aa8a6d5fb7343d30d95ac9c1 393 PIRSF PIRSF000138 1 384 1.3E-122 T 12-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 MIM_c19760 9f6c9ff9aa8a6d5fb7343d30d95ac9c1 393 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 279 285 - T 12-10-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Reactome: R-HSA-9033241 MIM_c19760 9f6c9ff9aa8a6d5fb7343d30d95ac9c1 393 SUPERFAMILY SSF51395 8 380 1.1E-90 T 12-10-2018 MIM_c19760 9f6c9ff9aa8a6d5fb7343d30d95ac9c1 393 Gene3D G3DSA:3.20.20.70 7 386 1.7E-118 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c19760 9f6c9ff9aa8a6d5fb7343d30d95ac9c1 393 Pfam PF01070 FMN-dependent dehydrogenase 17 381 6.5E-120 T 12-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 MIM_c36970 67cd2543716a88f3f2553ae5ccd96e43 311 SUPERFAMILY SSF53807 40 284 4.91E-44 T 12-10-2018 MIM_c36970 67cd2543716a88f3f2553ae5ccd96e43 311 Gene3D G3DSA:3.40.50.1980 160 289 1.3E-16 T 12-10-2018 MIM_c36970 67cd2543716a88f3f2553ae5ccd96e43 311 Gene3D G3DSA:3.40.50.1980 38 157 1.3E-29 T 12-10-2018 MIM_c36970 67cd2543716a88f3f2553ae5ccd96e43 311 Pfam PF01497 Periplasmic binding protein 43 235 4.8E-18 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain MIM_c31280 c89af26ae2b84510958da96c61b11940 170 Pfam PF07681 DoxX 39 131 2.8E-18 T 12-10-2018 IPR032808 DoxX family MIM_c34120 9de22cb42fbacc5cebdb497057fad1a3 302 Pfam PF03466 LysR substrate binding domain 86 283 4.3E-42 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c34120 9de22cb42fbacc5cebdb497057fad1a3 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 3.1E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c34120 9de22cb42fbacc5cebdb497057fad1a3 302 SUPERFAMILY SSF46785 1 110 3.2E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c34120 9de22cb42fbacc5cebdb497057fad1a3 302 SUPERFAMILY SSF53850 87 289 3.08E-45 T 12-10-2018 MIM_c34120 9de22cb42fbacc5cebdb497057fad1a3 302 Gene3D G3DSA:1.10.10.10 1 84 1.1E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c34120 9de22cb42fbacc5cebdb497057fad1a3 302 Gene3D G3DSA:3.40.190.290 89 285 6.0E-60 T 12-10-2018 MIM_c25510 5cbc973963f95f4b1645b2e83a451ead 136 Pfam PF04120 Low affinity iron permease 5 129 1.1E-52 T 12-10-2018 IPR007251 Low affinity iron permease, Fet4 GO:0055085 MIM_c29770 18d746ab9daf73c2790b5ba8570a2e27 409 SUPERFAMILY SSF50969 61 407 2.88E-96 T 12-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like MIM_c29770 18d746ab9daf73c2790b5ba8570a2e27 409 TIGRFAM TIGR02658 TTQ_MADH_Hv: methylamine dehydrogenase (amicyanin) heavy chain 54 406 8.1E-174 T 12-10-2018 IPR013476 Methylamine dehydrogenase heavy chain GO:0030058|GO:0030416|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 MIM_c29770 18d746ab9daf73c2790b5ba8570a2e27 409 Gene3D G3DSA:2.130.10.10 40 408 5.5E-109 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MIM_c29770 18d746ab9daf73c2790b5ba8570a2e27 409 Pfam PF06433 Methylamine dehydrogenase heavy chain (MADH) 68 404 5.7E-162 T 12-10-2018 IPR009451 Amine dehydrogenase heavy chain GO:0030058|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 MIM_c35390 fcd63a6f66c86ca6eeb0a63bd85e2d13 376 SUPERFAMILY SSF53850 33 274 3.01E-40 T 12-10-2018 MIM_c35390 fcd63a6f66c86ca6eeb0a63bd85e2d13 376 Gene3D G3DSA:3.40.190.10 126 228 1.0E-129 T 12-10-2018 MIM_c35390 fcd63a6f66c86ca6eeb0a63bd85e2d13 376 Pfam PF09084 NMT1/THI5 like 58 261 2.4E-19 T 12-10-2018 IPR015168 SsuA/THI5-like MIM_c35390 fcd63a6f66c86ca6eeb0a63bd85e2d13 376 Gene3D G3DSA:3.40.190.10 35 349 1.0E-129 T 12-10-2018 MIM_c16480 2c2782275e2312293dd3ba4410c6a6d1 433 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 9 253 4.9E-109 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MIM_c16480 2c2782275e2312293dd3ba4410c6a6d1 433 PIRSF PIRSF001362 1 433 1.2E-237 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MIM_c16480 2c2782275e2312293dd3ba4410c6a6d1 433 Pfam PF00463 Isocitrate lyase family 13 257 1.8E-59 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MIM_c16480 2c2782275e2312293dd3ba4410c6a6d1 433 SUPERFAMILY SSF51621 7 430 1.44E-157 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MIM_c16480 2c2782275e2312293dd3ba4410c6a6d1 433 ProSitePatterns PS00161 Isocitrate lyase signature. 191 196 - T 12-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 MIM_c16480 2c2782275e2312293dd3ba4410c6a6d1 433 Gene3D G3DSA:3.20.20.60 2 413 8.9E-171 T 12-10-2018 MIM_c25600 63272c5a21158f95c47d344c0277a759 170 SUPERFAMILY SSF55729 1 162 7.75E-25 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c25600 63272c5a21158f95c47d344c0277a759 170 Pfam PF00583 Acetyltransferase (GNAT) family 46 138 1.4E-13 T 12-10-2018 IPR000182 GNAT domain MIM_c25600 63272c5a21158f95c47d344c0277a759 170 Gene3D G3DSA:3.40.630.30 2 166 3.4E-32 T 12-10-2018 MIM_c19240 ac5b809e4d1e3978425e48eece6f9992 318 Gene3D G3DSA:3.30.70.1070 237 317 7.8E-13 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 MIM_c19240 ac5b809e4d1e3978425e48eece6f9992 318 Pfam PF05036 Sporulation related domain 241 315 7.4E-18 T 12-10-2018 IPR007730 Sporulation-like domain GO:0042834 MIM_c19240 ac5b809e4d1e3978425e48eece6f9992 318 SUPERFAMILY SSF110997 241 315 1.7E-15 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 MIM_c10880 5701bff0bd77233680dcddbaed3007fb 120 Pfam PF05521 Phage head-tail joining protein 7 113 1.9E-21 T 12-10-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor MIM_c10880 5701bff0bd77233680dcddbaed3007fb 120 Gene3D G3DSA:2.40.10.270 1 119 4.7E-16 T 12-10-2018 IPR038666 Bacteriophage SPP1, head-tail adaptor superfamily MIM_c36060 1c9734905dbe075de44ebbd3741a7563 400 SUPERFAMILY SSF54826 2 114 3.54E-21 T 12-10-2018 MIM_c36060 1c9734905dbe075de44ebbd3741a7563 400 Pfam PF13378 Enolase C-terminal domain-like 151 380 2.0E-36 T 12-10-2018 IPR029065 Enolase C-terminal domain-like MIM_c36060 1c9734905dbe075de44ebbd3741a7563 400 Gene3D G3DSA:3.30.390.10 8 376 3.7E-126 T 12-10-2018 IPR029017 Enolase-like, N-terminal MIM_c36060 1c9734905dbe075de44ebbd3741a7563 400 SMART SM00922 145 262 1.5E-8 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MIM_c36060 1c9734905dbe075de44ebbd3741a7563 400 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 17 110 1.3E-7 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain MIM_c36060 1c9734905dbe075de44ebbd3741a7563 400 SUPERFAMILY SSF51604 98 388 2.41E-60 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MIM_c36060 1c9734905dbe075de44ebbd3741a7563 400 Gene3D G3DSA:3.20.20.120 103 374 3.7E-126 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MIM_c06420 63dac5d5aab2945234c5a6f77792b573 452 Pfam PF02447 GntP family permease 4 450 7.0E-96 T 12-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 MIM_c13280 85121a11a475db07795ec1226f216dee 437 ProSitePatterns PS00480 Citrate synthase signature. 310 322 - T 12-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MIM_c13280 85121a11a475db07795ec1226f216dee 437 PRINTS PR00143 Citrate synthase signature 169 182 8.7E-55 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 MIM_c13280 85121a11a475db07795ec1226f216dee 437 PRINTS PR00143 Citrate synthase signature 223 238 8.7E-55 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 MIM_c13280 85121a11a475db07795ec1226f216dee 437 PRINTS PR00143 Citrate synthase signature 245 273 8.7E-55 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 MIM_c13280 85121a11a475db07795ec1226f216dee 437 PRINTS PR00143 Citrate synthase signature 387 401 8.7E-55 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 MIM_c13280 85121a11a475db07795ec1226f216dee 437 PRINTS PR00143 Citrate synthase signature 303 323 8.7E-55 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 MIM_c13280 85121a11a475db07795ec1226f216dee 437 PRINTS PR00143 Citrate synthase signature 367 383 8.7E-55 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 MIM_c13280 85121a11a475db07795ec1226f216dee 437 Gene3D G3DSA:1.10.230.10 272 384 4.3E-143 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain MIM_c13280 85121a11a475db07795ec1226f216dee 437 PIRSF PIRSF001369 41 437 7.1E-163 T 12-10-2018 IPR024176 Citrate synthase, bacterial-type MIM_c13280 85121a11a475db07795ec1226f216dee 437 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 17 430 4.4E-233 T 12-10-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 MIM_c13280 85121a11a475db07795ec1226f216dee 437 SUPERFAMILY SSF48256 10 436 3.27E-163 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 MIM_c13280 85121a11a475db07795ec1226f216dee 437 Gene3D G3DSA:2.20.28.60 1 54 2.6E-24 T 12-10-2018 MIM_c13280 85121a11a475db07795ec1226f216dee 437 Gene3D G3DSA:1.10.580.10 61 419 4.3E-143 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MIM_c13280 85121a11a475db07795ec1226f216dee 437 Pfam PF00285 Citrate synthase, C-terminal domain 50 419 2.5E-131 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 MIM_c33730 61a94d500c587d0f8c946ee42990aae4 265 SUPERFAMILY SSF51182 20 182 3.2E-19 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c33730 61a94d500c587d0f8c946ee42990aae4 265 Pfam PF02311 AraC-like ligand binding domain 28 101 4.1E-9 T 12-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 MIM_c33730 61a94d500c587d0f8c946ee42990aae4 265 SMART SM00342 173 255 4.1E-22 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c33730 61a94d500c587d0f8c946ee42990aae4 265 SUPERFAMILY SSF46689 212 257 3.49E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c33730 61a94d500c587d0f8c946ee42990aae4 265 Gene3D G3DSA:1.10.10.60 157 261 5.8E-21 T 12-10-2018 MIM_c33730 61a94d500c587d0f8c946ee42990aae4 265 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 224 239 6.3E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MIM_c33730 61a94d500c587d0f8c946ee42990aae4 265 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 239 255 6.3E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MIM_c33730 61a94d500c587d0f8c946ee42990aae4 265 Pfam PF12833 Helix-turn-helix domain 179 256 3.7E-22 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c33730 61a94d500c587d0f8c946ee42990aae4 265 Gene3D G3DSA:2.60.120.10 18 95 4.3E-9 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c38860 62124d4ab24ccc76a516c42b00e611cf 395 Pfam PF07394 Protein of unknown function (DUF1501) 33 382 2.5E-37 T 12-10-2018 IPR010869 Protein of unknown function DUF1501 MIM_c17540 b2b8375180072ac284f66980e063b91e 324 Gene3D G3DSA:3.40.190.10 127 249 4.8E-102 T 12-10-2018 MIM_c17540 b2b8375180072ac284f66980e063b91e 324 SUPERFAMILY SSF53850 118 280 1.05E-10 T 12-10-2018 MIM_c17540 b2b8375180072ac284f66980e063b91e 324 Gene3D G3DSA:3.40.190.150 30 314 4.8E-102 T 12-10-2018 MIM_c17540 b2b8375180072ac284f66980e063b91e 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 320 3.6E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c17540 b2b8375180072ac284f66980e063b91e 324 PIRSF PIRSF017082 1 323 7.3E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c06040 8d410efa3d88e0ba870dac7407ff2f94 323 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 20 306 5.8E-80 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MIM_c06040 8d410efa3d88e0ba870dac7407ff2f94 323 Gene3D G3DSA:3.40.50.1100 15 310 3.7E-120 T 12-10-2018 MIM_c06040 8d410efa3d88e0ba870dac7407ff2f94 323 SUPERFAMILY SSF53686 6 313 1.14E-96 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MIM_c06040 8d410efa3d88e0ba870dac7407ff2f94 323 Gene3D G3DSA:3.40.50.1100 53 149 3.7E-120 T 12-10-2018 MIM_c20960 4b5989dc02090527f99844c49d6ae33c 411 Gene3D G3DSA:1.10.540.10 1 120 1.9E-29 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c20960 4b5989dc02090527f99844c49d6ae33c 411 Gene3D G3DSA:1.20.140.10 237 385 1.4E-43 T 12-10-2018 MIM_c20960 4b5989dc02090527f99844c49d6ae33c 411 Gene3D G3DSA:2.40.110.10 122 236 2.0E-30 T 12-10-2018 MIM_c20960 4b5989dc02090527f99844c49d6ae33c 411 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 1.0E-24 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c20960 4b5989dc02090527f99844c49d6ae33c 411 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 379 5.9E-40 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MIM_c20960 4b5989dc02090527f99844c49d6ae33c 411 SUPERFAMILY SSF47203 229 384 1.77E-45 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c20960 4b5989dc02090527f99844c49d6ae33c 411 SUPERFAMILY SSF56645 3 244 9.42E-63 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c20960 4b5989dc02090527f99844c49d6ae33c 411 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 215 1.5E-14 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MIM_c09170 48dbf374ec42d751f27f78f94cc6da80 284 Pfam PF02569 Pantoate-beta-alanine ligase 2 278 2.2E-95 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 MIM_c09170 48dbf374ec42d751f27f78f94cc6da80 284 Gene3D G3DSA:3.40.50.620 2 175 2.5E-71 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c09170 48dbf374ec42d751f27f78f94cc6da80 284 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 278 8.2E-92 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 MIM_c09170 48dbf374ec42d751f27f78f94cc6da80 284 Hamap MF_00158 Pantothenate synthetase [panC]. 2 280 37.365 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 MIM_c09170 48dbf374ec42d751f27f78f94cc6da80 284 Gene3D G3DSA:3.30.1300.10 176 278 2.2E-31 T 12-10-2018 MIM_c09170 48dbf374ec42d751f27f78f94cc6da80 284 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 19 74 6.5E-8 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MIM_c09170 48dbf374ec42d751f27f78f94cc6da80 284 SUPERFAMILY SSF52374 2 281 1.47E-95 T 12-10-2018 MIM_c36210 0a69122f61d523ea567994ca420191c2 235 Gene3D G3DSA:3.40.50.620 2 234 1.4E-61 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c36210 0a69122f61d523ea567994ca420191c2 235 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 5 221 1.5E-59 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 MIM_c36210 0a69122f61d523ea567994ca420191c2 235 Pfam PF06508 Queuosine biosynthesis protein QueC 4 228 3.3E-70 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 MIM_c36210 0a69122f61d523ea567994ca420191c2 235 PIRSF PIRSF006293 1 234 1.9E-67 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 MIM_c36210 0a69122f61d523ea567994ca420191c2 235 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 3 234 47.895 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 MIM_c36210 0a69122f61d523ea567994ca420191c2 235 SUPERFAMILY SSF52402 2 228 3.53E-51 T 12-10-2018 MIM_c09140 9ac8e14c6329e2ea56cfffab44a95066 246 PIRSF PIRSF039085 2 246 1.1E-108 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MIM_c09140 9ac8e14c6329e2ea56cfffab44a95066 246 SUPERFAMILY SSF52540 5 240 5.8E-83 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c09140 9ac8e14c6329e2ea56cfffab44a95066 246 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c09140 9ac8e14c6329e2ea56cfffab44a95066 246 Gene3D G3DSA:3.40.50.300 3 246 4.0E-80 T 12-10-2018 MIM_c09140 9ac8e14c6329e2ea56cfffab44a95066 246 SMART SM00382 30 218 1.3E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c09140 9ac8e14c6329e2ea56cfffab44a95066 246 Pfam PF00005 ABC transporter 21 169 4.9E-40 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c01750 34d72135fb8fc3f1bfb87000b68c42e5 328 SUPERFAMILY SSF53850 121 286 1.33E-8 T 12-10-2018 MIM_c01750 34d72135fb8fc3f1bfb87000b68c42e5 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 57 324 5.3E-66 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c01750 34d72135fb8fc3f1bfb87000b68c42e5 328 PIRSF PIRSF017082 5 327 1.5E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c01750 34d72135fb8fc3f1bfb87000b68c42e5 328 Gene3D G3DSA:3.40.190.10 134 252 7.5E-86 T 12-10-2018 MIM_c01750 34d72135fb8fc3f1bfb87000b68c42e5 328 Gene3D G3DSA:3.40.190.150 38 317 7.5E-86 T 12-10-2018 MIM_c33570 9713bafc85e89ac7899028b2dd643714 510 SUPERFAMILY SSF103473 17 493 2.62E-33 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c33570 9713bafc85e89ac7899028b2dd643714 510 Pfam PF07690 Major Facilitator Superfamily 22 312 1.3E-17 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c33570 9713bafc85e89ac7899028b2dd643714 510 Gene3D G3DSA:1.20.1250.20 13 207 2.2E-19 T 12-10-2018 MIM_c33570 9713bafc85e89ac7899028b2dd643714 510 Gene3D G3DSA:1.20.1250.20 272 499 3.4E-8 T 12-10-2018 MIM_c12220 4dcb21f699b3bab72da0f2974bb8a903 1186 Gene3D G3DSA:3.40.920.10 738 942 1.2E-18 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 MIM_c12220 4dcb21f699b3bab72da0f2974bb8a903 1186 SUPERFAMILY SSF52518 28 217 1.12E-16 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c12220 4dcb21f699b3bab72da0f2974bb8a903 1186 SUPERFAMILY SSF52518 457 637 7.21E-12 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c12220 4dcb21f699b3bab72da0f2974bb8a903 1186 SUPERFAMILY SSF53323 742 941 3.4E-30 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 MIM_c12220 4dcb21f699b3bab72da0f2974bb8a903 1186 Gene3D G3DSA:3.40.50.970 15 233 1.5E-27 T 12-10-2018 MIM_c12220 4dcb21f699b3bab72da0f2974bb8a903 1186 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 477 561 6.7E-5 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MIM_c12220 4dcb21f699b3bab72da0f2974bb8a903 1186 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 750 937 4.3E-23 T 12-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 MIM_c40350 486868dba98d79a5f869946025a4cb89 250 SUPERFAMILY SSF53901 45 164 2.37E-5 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c40350 486868dba98d79a5f869946025a4cb89 250 Pfam PF13723 Beta-ketoacyl synthase, N-terminal domain 24 246 1.1E-65 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MIM_c09630 ab1baa235e7ad7fbf5a961975cb1ec6f 241 SMART SM00895 102 228 1.8E-17 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c09630 ab1baa235e7ad7fbf5a961975cb1ec6f 241 SMART SM00345 10 69 3.5E-23 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c09630 ab1baa235e7ad7fbf5a961975cb1ec6f 241 Gene3D G3DSA:1.20.120.530 88 233 9.9E-21 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c09630 ab1baa235e7ad7fbf5a961975cb1ec6f 241 Pfam PF07729 FCD domain 102 227 1.5E-15 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c09630 ab1baa235e7ad7fbf5a961975cb1ec6f 241 SUPERFAMILY SSF46785 5 73 1.09E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c09630 ab1baa235e7ad7fbf5a961975cb1ec6f 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 69 4.2E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c09630 ab1baa235e7ad7fbf5a961975cb1ec6f 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 5.4E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c09630 ab1baa235e7ad7fbf5a961975cb1ec6f 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 5.4E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c09630 ab1baa235e7ad7fbf5a961975cb1ec6f 241 Gene3D G3DSA:1.10.10.10 1 74 1.1E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c09630 ab1baa235e7ad7fbf5a961975cb1ec6f 241 SUPERFAMILY SSF48008 101 234 1.86E-18 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c16570 dc2b78877024aefe26cf16ebb4657f50 309 Gene3D G3DSA:3.20.20.70 1 233 6.3E-60 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c16570 dc2b78877024aefe26cf16ebb4657f50 309 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 1 309 42.152 T 12-10-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 MIM_c16570 dc2b78877024aefe26cf16ebb4657f50 309 TIGRFAM TIGR00742 yjbN: tRNA dihydrouridine synthase A 1 308 3.0E-120 T 12-10-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 MIM_c16570 dc2b78877024aefe26cf16ebb4657f50 309 Gene3D G3DSA:1.20.120.1460 239 304 1.4E-14 T 12-10-2018 MIM_c16570 dc2b78877024aefe26cf16ebb4657f50 309 SUPERFAMILY SSF51395 1 289 5.7E-58 T 12-10-2018 MIM_c16570 dc2b78877024aefe26cf16ebb4657f50 309 Pfam PF01207 Dihydrouridine synthase (Dus) 1 296 2.8E-70 T 12-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MIM_c16570 dc2b78877024aefe26cf16ebb4657f50 309 PIRSF PIRSF006621 1 297 1.3E-59 T 12-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MIM_c16570 dc2b78877024aefe26cf16ebb4657f50 309 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 77 95 - T 12-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 MIM_c20730 b9a81f33d0872eba51df17bc8d6c60df 492 Pfam PF00171 Aldehyde dehydrogenase family 28 485 2.4E-142 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c20730 b9a81f33d0872eba51df17bc8d6c60df 492 Gene3D G3DSA:3.40.605.10 24 483 1.5E-147 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c20730 b9a81f33d0872eba51df17bc8d6c60df 492 SUPERFAMILY SSF53720 12 489 2.88E-145 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c20730 b9a81f33d0872eba51df17bc8d6c60df 492 Gene3D G3DSA:3.40.309.10 266 455 1.5E-147 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MIM_c23580 c26b54cbef8e59a0c885966d70bd1455 235 SUPERFAMILY SSF100950 2 228 1.26E-87 T 12-10-2018 IPR037171 NagB/RpiA transferase-like MIM_c23580 c26b54cbef8e59a0c885966d70bd1455 235 Pfam PF01144 Coenzyme A transferase 7 217 1.8E-79 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MIM_c23580 c26b54cbef8e59a0c885966d70bd1455 235 Gene3D G3DSA:3.40.1080.10 1 227 1.1E-95 T 12-10-2018 MIM_c23580 c26b54cbef8e59a0c885966d70bd1455 235 SMART SM00882 5 217 3.9E-90 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MIM_c23580 c26b54cbef8e59a0c885966d70bd1455 235 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 217 1.1E-80 T 12-10-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 MIM_c34150 7da286165407f6acd967e9e995ee1724 320 SMART SM00342 234 317 1.7E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c34150 7da286165407f6acd967e9e995ee1724 320 SUPERFAMILY SSF46689 270 316 2.28E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c34150 7da286165407f6acd967e9e995ee1724 320 Pfam PF12833 Helix-turn-helix domain 240 317 1.6E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c34150 7da286165407f6acd967e9e995ee1724 320 Gene3D G3DSA:1.10.10.60 212 320 2.1E-24 T 12-10-2018 MIM_c34150 7da286165407f6acd967e9e995ee1724 320 Pfam PF14525 AraC-binding-like domain 20 203 3.1E-16 T 12-10-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like MIM_c34150 7da286165407f6acd967e9e995ee1724 320 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 286 301 4.9E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MIM_c34150 7da286165407f6acd967e9e995ee1724 320 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 301 317 4.9E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MIM_c36450 0b5aaac64a1c202c22949112f7766cae 259 Gene3D G3DSA:3.40.50.150 14 252 5.8E-43 T 12-10-2018 MIM_c36450 0b5aaac64a1c202c22949112f7766cae 259 SUPERFAMILY SSF53335 18 217 2.05E-38 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c36450 0b5aaac64a1c202c22949112f7766cae 259 Pfam PF08241 Methyltransferase domain 51 139 7.3E-22 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 MIM_c01710 285d7880efbc5100439cbb68c9c820d1 353 Pfam PF13377 Periplasmic binding protein-like domain 183 349 9.1E-27 T 12-10-2018 MIM_c01710 285d7880efbc5100439cbb68c9c820d1 353 SUPERFAMILY SSF47413 17 72 4.31E-14 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c01710 285d7880efbc5100439cbb68c9c820d1 353 SUPERFAMILY SSF53822 76 335 4.04E-47 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c01710 285d7880efbc5100439cbb68c9c820d1 353 Gene3D G3DSA:3.40.50.2300 80 323 6.2E-52 T 12-10-2018 MIM_c01710 285d7880efbc5100439cbb68c9c820d1 353 Gene3D G3DSA:3.40.50.2300 172 307 6.2E-52 T 12-10-2018 MIM_c01710 285d7880efbc5100439cbb68c9c820d1 353 Pfam PF00356 Bacterial regulatory proteins, lacI family 18 63 1.9E-14 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MIM_c01710 285d7880efbc5100439cbb68c9c820d1 353 Gene3D G3DSA:1.10.260.40 8 73 1.4E-18 T 12-10-2018 MIM_c01710 285d7880efbc5100439cbb68c9c820d1 353 SMART SM00354 16 86 1.2E-16 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MIM_c29800 8a6cca28017368fc5aa3cf98e5827337 226 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 67 78 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MIM_c29800 8a6cca28017368fc5aa3cf98e5827337 226 Gene3D G3DSA:3.30.70.20 61 138 9.3E-14 T 12-10-2018 MIM_c29800 8a6cca28017368fc5aa3cf98e5827337 226 Gene3D G3DSA:3.30.70.20 141 216 8.5E-10 T 12-10-2018 MIM_c29800 8a6cca28017368fc5aa3cf98e5827337 226 Pfam PF12838 4Fe-4S dicluster domain 66 121 1.6E-8 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MIM_c29800 8a6cca28017368fc5aa3cf98e5827337 226 TIGRFAM TIGR00397 mauM_napG: MauM/NapG family ferredoxin-type protein 15 225 6.5E-99 T 12-10-2018 IPR004494 MauM/NapG ferredoxin-type protein MIM_c29800 8a6cca28017368fc5aa3cf98e5827337 226 SUPERFAMILY SSF54862 53 202 4.61E-25 T 12-10-2018 MIM_c00410 161f21973d8602f98bad72895048190e 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 45 209 1.2E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c00410 161f21973d8602f98bad72895048190e 216 SUPERFAMILY SSF161098 7 202 2.22E-47 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c00410 161f21973d8602f98bad72895048190e 216 Gene3D G3DSA:1.10.3720.10 4 214 4.6E-51 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c28480 dd245104e3a94ccd46f410b39d3944e8 174 Gene3D G3DSA:3.40.980.10 5 174 1.3E-39 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily MIM_c28480 dd245104e3a94ccd46f410b39d3944e8 174 SUPERFAMILY SSF53218 12 168 1.1E-35 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily MIM_c28480 dd245104e3a94ccd46f410b39d3944e8 174 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 13 154 2.1E-27 T 12-10-2018 IPR001453 MoaB/Mog domain MIM_c28480 dd245104e3a94ccd46f410b39d3944e8 174 Pfam PF00994 Probable molybdopterin binding domain 16 156 3.2E-25 T 12-10-2018 IPR001453 MoaB/Mog domain MIM_c28480 dd245104e3a94ccd46f410b39d3944e8 174 SMART SM00852 16 160 2.7E-20 T 12-10-2018 IPR001453 MoaB/Mog domain MIM_c28480 dd245104e3a94ccd46f410b39d3944e8 174 PIRSF PIRSF006443 1 168 4.3E-55 T 12-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 MIM_c30870 46a3f77d914224fff63abd280f6bf63e 321 PIRSF PIRSF017082 1 321 1.9E-83 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c30870 46a3f77d914224fff63abd280f6bf63e 321 SUPERFAMILY SSF53850 101 284 1.56E-10 T 12-10-2018 MIM_c30870 46a3f77d914224fff63abd280f6bf63e 321 Gene3D G3DSA:3.40.190.150 26 310 7.1E-109 T 12-10-2018 MIM_c30870 46a3f77d914224fff63abd280f6bf63e 321 Gene3D G3DSA:3.40.190.10 123 246 7.1E-109 T 12-10-2018 MIM_c30870 46a3f77d914224fff63abd280f6bf63e 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 317 6.1E-83 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c01960 4b738864dd8ce2376ffb64d75be6edeb 416 PIRSF PIRSF000018 13 416 2.8E-125 T 12-10-2018 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 MIM_c01960 4b738864dd8ce2376ffb64d75be6edeb 416 Gene3D G3DSA:1.10.760.10 301 416 1.6E-24 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c01960 4b738864dd8ce2376ffb64d75be6edeb 416 Gene3D G3DSA:1.10.760.10 1 152 2.9E-19 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c01960 4b738864dd8ce2376ffb64d75be6edeb 416 Gene3D G3DSA:1.10.760.10 163 300 8.3E-6 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c01960 4b738864dd8ce2376ffb64d75be6edeb 416 Pfam PF00034 Cytochrome c 312 397 4.3E-9 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c01960 4b738864dd8ce2376ffb64d75be6edeb 416 Pfam PF00034 Cytochrome c 47 146 9.4E-9 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c01960 4b738864dd8ce2376ffb64d75be6edeb 416 SUPERFAMILY SSF46626 38 167 3.67E-27 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c01960 4b738864dd8ce2376ffb64d75be6edeb 416 SUPERFAMILY SSF46626 190 294 1.68E-11 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c01960 4b738864dd8ce2376ffb64d75be6edeb 416 SUPERFAMILY SSF46626 312 402 5.5E-21 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c08730 66eb109aaf72ed257604bb2f654cbd27 317 PIRSF PIRSF017082 1 317 4.1E-88 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c08730 66eb109aaf72ed257604bb2f654cbd27 317 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 58 314 3.0E-26 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c08730 66eb109aaf72ed257604bb2f654cbd27 317 SUPERFAMILY SSF53850 91 224 4.62E-9 T 12-10-2018 MIM_c08730 66eb109aaf72ed257604bb2f654cbd27 317 Gene3D G3DSA:3.40.190.150 24 308 6.1E-64 T 12-10-2018 MIM_c08730 66eb109aaf72ed257604bb2f654cbd27 317 Gene3D G3DSA:3.40.190.10 119 243 6.1E-64 T 12-10-2018 MIM_c30370 4359d8767a0a681ebd2539ca51ec720c 312 SUPERFAMILY SSF103481 52 146 6.93E-13 T 12-10-2018 MIM_c30370 4359d8767a0a681ebd2539ca51ec720c 312 SUPERFAMILY SSF103481 194 297 9.94E-13 T 12-10-2018 MIM_c30370 4359d8767a0a681ebd2539ca51ec720c 312 Pfam PF00892 EamA-like transporter family 159 294 4.1E-19 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MIM_c30370 4359d8767a0a681ebd2539ca51ec720c 312 Pfam PF00892 EamA-like transporter family 14 143 1.4E-16 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MIM_c08810 e841bedd8c40769353f5fc501b4789fb 359 Gene3D G3DSA:2.102.10.10 3 130 8.6E-36 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MIM_c08810 e841bedd8c40769353f5fc501b4789fb 359 Pfam PF00355 Rieske [2Fe-2S] domain 7 85 1.0E-14 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MIM_c08810 e841bedd8c40769353f5fc501b4789fb 359 SUPERFAMILY SSF50022 2 111 2.36E-28 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MIM_c08810 e841bedd8c40769353f5fc501b4789fb 359 SUPERFAMILY SSF55961 102 337 7.06E-44 T 12-10-2018 MIM_c08810 e841bedd8c40769353f5fc501b4789fb 359 Gene3D G3DSA:3.30.530.90 131 344 2.7E-48 T 12-10-2018 MIM_c16600 28f565dde0b7d8a40b9cb8549424af5f 110 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 11 73 1.2E-9 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MIM_c16600 28f565dde0b7d8a40b9cb8549424af5f 110 SUPERFAMILY SSF54292 7 80 2.62E-18 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MIM_c16600 28f565dde0b7d8a40b9cb8549424af5f 110 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 34 42 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MIM_c16600 28f565dde0b7d8a40b9cb8549424af5f 110 Gene3D G3DSA:3.10.20.30 1 88 6.7E-16 T 12-10-2018 IPR012675 Beta-grasp domain superfamily MIM_c07490 507aabbda2c1608a526f888deb4599ac 180 PRINTS PR00125 ATP synthase delta subunit signature 76 87 9.3E-22 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07490 507aabbda2c1608a526f888deb4599ac 180 PRINTS PR00125 ATP synthase delta subunit signature 7 26 9.3E-22 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07490 507aabbda2c1608a526f888deb4599ac 180 PRINTS PR00125 ATP synthase delta subunit signature 87 101 9.3E-22 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07490 507aabbda2c1608a526f888deb4599ac 180 PRINTS PR00125 ATP synthase delta subunit signature 137 152 9.3E-22 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07490 507aabbda2c1608a526f888deb4599ac 180 PRINTS PR00125 ATP synthase delta subunit signature 152 170 9.3E-22 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07490 507aabbda2c1608a526f888deb4599ac 180 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 179 19.695 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07490 507aabbda2c1608a526f888deb4599ac 180 SUPERFAMILY SSF47928 3 107 5.23E-21 T 12-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07490 507aabbda2c1608a526f888deb4599ac 180 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 7 177 1.7E-39 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07490 507aabbda2c1608a526f888deb4599ac 180 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 177 2.0E-48 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07490 507aabbda2c1608a526f888deb4599ac 180 Gene3D G3DSA:1.10.520.20 2 108 7.3E-26 T 12-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c13420 489af6533eceb9309369abddf530ffcc 359 ProSitePatterns PS00211 ABC transporters family signature. 178 192 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c13420 489af6533eceb9309369abddf530ffcc 359 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 256 327 4.8E-23 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c13420 489af6533eceb9309369abddf530ffcc 359 Pfam PF00005 ABC transporter 46 205 2.3E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c13420 489af6533eceb9309369abddf530ffcc 359 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 257 321 1.5E-18 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c13420 489af6533eceb9309369abddf530ffcc 359 SMART SM00382 55 255 8.4E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c13420 489af6533eceb9309369abddf530ffcc 359 Gene3D G3DSA:3.40.50.300 25 356 1.6E-90 T 12-10-2018 MIM_c13420 489af6533eceb9309369abddf530ffcc 359 SUPERFAMILY SSF52540 26 276 3.94E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c40820 9815bde076f3eef4782130d0b2c85902 503 Gene3D G3DSA:1.20.1250.20 269 461 1.6E-14 T 12-10-2018 MIM_c40820 9815bde076f3eef4782130d0b2c85902 503 Gene3D G3DSA:1.20.1250.20 14 199 1.2E-32 T 12-10-2018 MIM_c40820 9815bde076f3eef4782130d0b2c85902 503 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 22 424 6.7E-70 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 MIM_c40820 9815bde076f3eef4782130d0b2c85902 503 SUPERFAMILY SSF103473 17 460 9.42E-58 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c40820 9815bde076f3eef4782130d0b2c85902 503 Pfam PF07690 Major Facilitator Superfamily 21 412 2.3E-47 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c15880 db70926bf8f6ebd0712cb438765de6e2 766 SMART SM01086 656 746 1.4E-30 T 12-10-2018 IPR019489 Clp ATPase, C-terminal MIM_c15880 db70926bf8f6ebd0712cb438765de6e2 766 Gene3D G3DSA:1.10.1780.10 1 144 2.1E-36 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 MIM_c15880 db70926bf8f6ebd0712cb438765de6e2 766 SUPERFAMILY SSF52540 440 743 2.96E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c15880 db70926bf8f6ebd0712cb438765de6e2 766 Gene3D G3DSA:1.10.8.60 354 441 3.1E-31 T 12-10-2018 MIM_c15880 db70926bf8f6ebd0712cb438765de6e2 766 Gene3D G3DSA:3.40.50.300 442 654 7.1E-80 T 12-10-2018 MIM_c15880 db70926bf8f6ebd0712cb438765de6e2 766 SUPERFAMILY SSF81923 2 143 1.83E-53 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 MIM_c15880 db70926bf8f6ebd0712cb438765de6e2 766 Gene3D G3DSA:3.40.50.300 160 353 2.4E-65 T 12-10-2018 MIM_c15880 db70926bf8f6ebd0712cb438765de6e2 766 SMART SM00382 209 353 4.3E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c15880 db70926bf8f6ebd0712cb438765de6e2 766 SMART SM00382 490 626 6.9E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c15880 db70926bf8f6ebd0712cb438765de6e2 766 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 214 326 2.3E-11 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MIM_c15880 db70926bf8f6ebd0712cb438765de6e2 766 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 305 317 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 MIM_c15880 db70926bf8f6ebd0712cb438765de6e2 766 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 3 737 0.0 T 12-10-2018 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0016887|GO:0043335 MIM_c15880 db70926bf8f6ebd0712cb438765de6e2 766 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 62 1.5E-11 T 12-10-2018 IPR004176 Clp, N-terminal MIM_c15880 db70926bf8f6ebd0712cb438765de6e2 766 Gene3D G3DSA:1.10.8.60 656 761 2.5E-27 T 12-10-2018 MIM_c15880 db70926bf8f6ebd0712cb438765de6e2 766 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 656 736 1.0E-21 T 12-10-2018 IPR019489 Clp ATPase, C-terminal MIM_c15880 db70926bf8f6ebd0712cb438765de6e2 766 SUPERFAMILY SSF52540 175 415 2.52E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c15880 db70926bf8f6ebd0712cb438765de6e2 766 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 494 512 1.4E-38 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 MIM_c15880 db70926bf8f6ebd0712cb438765de6e2 766 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 536 554 1.4E-38 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 MIM_c15880 db70926bf8f6ebd0712cb438765de6e2 766 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 565 583 1.4E-38 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 MIM_c15880 db70926bf8f6ebd0712cb438765de6e2 766 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 598 612 1.4E-38 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 MIM_c15880 db70926bf8f6ebd0712cb438765de6e2 766 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 521 539 - T 12-10-2018 IPR028299 ClpA/B, conserved site 2 MIM_c15880 db70926bf8f6ebd0712cb438765de6e2 766 Pfam PF07724 AAA domain (Cdc48 subfamily) 489 650 7.0E-47 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MIM_c02570 945430afef62f861e4389f4d130c99de 312 Gene3D G3DSA:3.40.190.10 96 293 5.9E-52 T 12-10-2018 MIM_c02570 945430afef62f861e4389f4d130c99de 312 Gene3D G3DSA:1.10.10.10 7 92 2.9E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c02570 945430afef62f861e4389f4d130c99de 312 SUPERFAMILY SSF46785 10 92 4.45E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c02570 945430afef62f861e4389f4d130c99de 312 Gene3D G3DSA:3.40.190.10 167 268 5.9E-52 T 12-10-2018 MIM_c02570 945430afef62f861e4389f4d130c99de 312 Pfam PF03466 LysR substrate binding domain 92 297 4.5E-33 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c02570 945430afef62f861e4389f4d130c99de 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 66 4.4E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c02570 945430afef62f861e4389f4d130c99de 312 SUPERFAMILY SSF53850 93 300 1.01E-36 T 12-10-2018 MIM_c08910 c71f456a42c160d924b40e2147d7dad4 268 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 21 263 3.8E-36 T 12-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 MIM_c08910 c71f456a42c160d924b40e2147d7dad4 268 PIRSF PIRSF006157 1 265 2.3E-87 T 12-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 MIM_c08910 c71f456a42c160d924b40e2147d7dad4 268 SUPERFAMILY SSF53213 3 263 1.18E-81 T 12-10-2018 MIM_c08910 c71f456a42c160d924b40e2147d7dad4 268 Gene3D G3DSA:3.40.830.10 1 264 1.8E-86 T 12-10-2018 MIM_c03150 51a23034955e59c21239994cb07ac4f2 448 Pfam PF04775 Acyl-CoA thioester hydrolase/BAAT N-terminal region 20 140 1.3E-32 T 12-10-2018 IPR006862 Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase MIM_c03150 51a23034955e59c21239994cb07ac4f2 448 Gene3D G3DSA:3.40.50.1820 134 431 1.3E-59 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c03150 51a23034955e59c21239994cb07ac4f2 448 SUPERFAMILY SSF53474 68 431 1.29E-29 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c03150 51a23034955e59c21239994cb07ac4f2 448 Gene3D G3DSA:2.60.40.2240 4 133 4.7E-30 T 12-10-2018 MIM_c03150 51a23034955e59c21239994cb07ac4f2 448 Pfam PF08840 BAAT / Acyl-CoA thioester hydrolase C terminal 203 432 1.0E-52 T 12-10-2018 IPR014940 BAAT/Acyl-CoA thioester hydrolase C-terminal MIM_c03150 51a23034955e59c21239994cb07ac4f2 448 PIRSF PIRSF016521 5 439 1.3E-106 T 12-10-2018 IPR016662 Acyl-CoA thioesterase, long chain GO:0006637|GO:0016790 MIM_c23940 85c84ec728cf6f69400acfc6f8b9d2e4 346 Gene3D G3DSA:3.40.718.10 1 344 3.7E-125 T 12-10-2018 MIM_c23940 85c84ec728cf6f69400acfc6f8b9d2e4 346 Pfam PF02504 Fatty acid synthesis protein 2 322 4.2E-106 T 12-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 MIM_c23940 85c84ec728cf6f69400acfc6f8b9d2e4 346 SUPERFAMILY SSF53659 2 329 3.17E-104 T 12-10-2018 MIM_c23940 85c84ec728cf6f69400acfc6f8b9d2e4 346 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 340 147.345 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 MIM_c23940 85c84ec728cf6f69400acfc6f8b9d2e4 346 PIRSF PIRSF002465 1 337 2.5E-128 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 MIM_c23940 85c84ec728cf6f69400acfc6f8b9d2e4 346 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 2 332 1.7E-109 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 MIM_c20190 ac16e44b21b277f1ca159c1e6f1d692e 415 Gene3D G3DSA:3.40.50.10540 10 349 7.7E-107 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c20190 ac16e44b21b277f1ca159c1e6f1d692e 415 Gene3D G3DSA:3.30.1540.10 237 328 7.7E-107 T 12-10-2018 MIM_c20190 ac16e44b21b277f1ca159c1e6f1d692e 415 SUPERFAMILY SSF89796 8 405 1.03E-108 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c20190 ac16e44b21b277f1ca159c1e6f1d692e 415 Pfam PF02515 CoA-transferase family III 11 380 1.6E-100 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 MIM_c17600 5767d2efd800b427f062a226ac6b632e 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.9E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c17600 5767d2efd800b427f062a226ac6b632e 305 Gene3D G3DSA:1.10.10.10 1 88 9.4E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c17600 5767d2efd800b427f062a226ac6b632e 305 Gene3D G3DSA:3.40.190.10 167 271 2.1E-39 T 12-10-2018 MIM_c17600 5767d2efd800b427f062a226ac6b632e 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.7E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c17600 5767d2efd800b427f062a226ac6b632e 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.7E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c17600 5767d2efd800b427f062a226ac6b632e 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.7E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c17600 5767d2efd800b427f062a226ac6b632e 305 Pfam PF03466 LysR substrate binding domain 94 296 5.5E-25 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c17600 5767d2efd800b427f062a226ac6b632e 305 SUPERFAMILY SSF46785 2 88 3.39E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c17600 5767d2efd800b427f062a226ac6b632e 305 SUPERFAMILY SSF53850 94 299 2.96E-26 T 12-10-2018 MIM_c17600 5767d2efd800b427f062a226ac6b632e 305 Gene3D G3DSA:3.40.190.10 94 286 2.1E-39 T 12-10-2018 MIM_c40850 e86697ff40706da133d1fb3773e3179f 141 Gene3D G3DSA:3.10.180.10 2 139 1.9E-37 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c40850 e86697ff40706da133d1fb3773e3179f 141 SUPERFAMILY SSF54593 6 131 9.13E-24 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c40850 e86697ff40706da133d1fb3773e3179f 141 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 129 2.7E-9 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MIM_c06700 e8d3864a1b1d9aa97edd8f3a7d475128 317 TIGRFAM TIGR02193 heptsyl_trn_I: lipopolysaccharide heptosyltransferase I 4 314 5.0E-115 T 12-10-2018 IPR011908 Lipopolysaccharide heptosyltransferase I GO:0008920|GO:0009244 MIM_c06700 e8d3864a1b1d9aa97edd8f3a7d475128 317 Gene3D G3DSA:3.40.50.2000 3 162 3.9E-58 T 12-10-2018 MIM_c06700 e8d3864a1b1d9aa97edd8f3a7d475128 317 Gene3D G3DSA:3.40.50.2000 166 300 2.4E-34 T 12-10-2018 MIM_c06700 e8d3864a1b1d9aa97edd8f3a7d475128 317 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 77 304 7.8E-61 T 12-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 MIM_c06700 e8d3864a1b1d9aa97edd8f3a7d475128 317 SUPERFAMILY SSF53756 3 315 2.2E-68 T 12-10-2018 MIM_c20380 261764ae0e7933eb414e7fe7cd27a7b3 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 320 1.3E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c20380 261764ae0e7933eb414e7fe7cd27a7b3 323 SUPERFAMILY SSF53850 112 284 4.22E-14 T 12-10-2018 MIM_c20380 261764ae0e7933eb414e7fe7cd27a7b3 323 Gene3D G3DSA:3.40.190.150 29 313 6.4E-99 T 12-10-2018 MIM_c20380 261764ae0e7933eb414e7fe7cd27a7b3 323 Gene3D G3DSA:3.40.190.10 125 248 6.4E-99 T 12-10-2018 MIM_c20380 261764ae0e7933eb414e7fe7cd27a7b3 323 PIRSF PIRSF017082 2 323 2.9E-81 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c36900 3b055be16547d7308c25db88afb2a6b3 132 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MIM_c36900 3b055be16547d7308c25db88afb2a6b3 132 Pfam PF09278 MerR, DNA binding 46 106 1.7E-18 T 12-10-2018 IPR015358 Transcription regulator MerR, DNA binding MIM_c36900 3b055be16547d7308c25db88afb2a6b3 132 SUPERFAMILY SSF46955 1 126 1.65E-38 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily MIM_c36900 3b055be16547d7308c25db88afb2a6b3 132 SMART SM00422 1 70 1.4E-27 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MIM_c36900 3b055be16547d7308c25db88afb2a6b3 132 Pfam PF00376 MerR family regulatory protein 2 39 5.7E-15 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MIM_c36900 3b055be16547d7308c25db88afb2a6b3 132 Gene3D G3DSA:1.10.1660.10 1 125 9.5E-36 T 12-10-2018 MIM_c36900 3b055be16547d7308c25db88afb2a6b3 132 TIGRFAM TIGR02044 CueR: Cu(I)-responsive transcriptional regulator 1 126 6.5E-49 T 12-10-2018 IPR011789 Cu(I)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0005507|GO:0045893 MIM_c36900 3b055be16547d7308c25db88afb2a6b3 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 4.4E-9 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MIM_c36900 3b055be16547d7308c25db88afb2a6b3 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 4.4E-9 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MIM_c36900 3b055be16547d7308c25db88afb2a6b3 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 4.4E-9 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MIM_c32520 6fc869fcb14e9091c51011690d99eccc 383 Gene3D G3DSA:3.40.50.2000 176 362 1.0E-56 T 12-10-2018 MIM_c32520 6fc869fcb14e9091c51011690d99eccc 383 Pfam PF13439 Glycosyltransferase Family 4 18 180 3.4E-14 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MIM_c32520 6fc869fcb14e9091c51011690d99eccc 383 SUPERFAMILY SSF53756 8 375 5.89E-70 T 12-10-2018 MIM_c32520 6fc869fcb14e9091c51011690d99eccc 383 Pfam PF13692 Glycosyl transferases group 1 202 335 3.6E-26 T 12-10-2018 MIM_c32520 6fc869fcb14e9091c51011690d99eccc 383 Gene3D G3DSA:3.40.50.2000 68 373 1.0E-56 T 12-10-2018 MIM_c11790 705384ee5405a496bcf48622f644a733 319 SUPERFAMILY SSF51905 3 314 2.73E-51 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c11790 705384ee5405a496bcf48622f644a733 319 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 301 7.4E-44 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MIM_c11790 705384ee5405a496bcf48622f644a733 319 Gene3D G3DSA:3.50.50.60 120 245 6.8E-115 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c11790 705384ee5405a496bcf48622f644a733 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 63 73 6.2E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MIM_c11790 705384ee5405a496bcf48622f644a733 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 239 260 6.2E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MIM_c11790 705384ee5405a496bcf48622f644a733 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 109 117 6.2E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MIM_c11790 705384ee5405a496bcf48622f644a733 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 131 143 6.2E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MIM_c11790 705384ee5405a496bcf48622f644a733 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 201 217 6.2E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MIM_c11790 705384ee5405a496bcf48622f644a733 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 277 295 6.2E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MIM_c11790 705384ee5405a496bcf48622f644a733 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 6.2E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MIM_c11790 705384ee5405a496bcf48622f644a733 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 146 170 6.2E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MIM_c11790 705384ee5405a496bcf48622f644a733 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 42 57 6.2E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MIM_c11790 705384ee5405a496bcf48622f644a733 319 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 9 314 2.5E-114 T 12-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 MIM_c11790 705384ee5405a496bcf48622f644a733 319 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 138 158 - T 12-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 MIM_c11790 705384ee5405a496bcf48622f644a733 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 1.7E-38 T 12-10-2018 MIM_c11790 705384ee5405a496bcf48622f644a733 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 1.7E-38 T 12-10-2018 MIM_c11790 705384ee5405a496bcf48622f644a733 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 1.7E-38 T 12-10-2018 MIM_c11790 705384ee5405a496bcf48622f644a733 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 1.7E-38 T 12-10-2018 MIM_c11790 705384ee5405a496bcf48622f644a733 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 253 1.7E-38 T 12-10-2018 MIM_c11790 705384ee5405a496bcf48622f644a733 319 Gene3D G3DSA:3.50.50.60 11 313 6.8E-115 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c16200 d98ed245c517d23fa67f0ae79316599d 201 SUPERFAMILY SSF54909 117 173 2.95E-6 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel MIM_c01450 455f78484fce6363d50aa108de00c1fd 157 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 1 101 3.3E-20 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain MIM_c01450 455f78484fce6363d50aa108de00c1fd 157 SUPERFAMILY SSF53927 3 130 3.72E-38 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 MIM_c01450 455f78484fce6363d50aa108de00c1fd 157 Gene3D G3DSA:3.40.140.10 2 157 1.1E-46 T 12-10-2018 MIM_c01450 455f78484fce6363d50aa108de00c1fd 157 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 90 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MIM_c23670 00aba0ee259d4f299909e5773fca64d0 641 Gene3D G3DSA:3.40.50.720 303 482 1.5E-53 T 12-10-2018 MIM_c23670 00aba0ee259d4f299909e5773fca64d0 641 SUPERFAMILY SSF48179 480 574 9.35E-28 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c23670 00aba0ee259d4f299909e5773fca64d0 641 Gene3D G3DSA:3.90.226.10 4 302 1.5E-72 T 12-10-2018 MIM_c23670 00aba0ee259d4f299909e5773fca64d0 641 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 306 479 2.8E-46 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MIM_c23670 00aba0ee259d4f299909e5773fca64d0 641 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 203 3.4E-30 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c23670 00aba0ee259d4f299909e5773fca64d0 641 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 481 569 7.4E-22 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MIM_c23670 00aba0ee259d4f299909e5773fca64d0 641 Gene3D G3DSA:1.10.1040.50 483 641 3.2E-40 T 12-10-2018 MIM_c23670 00aba0ee259d4f299909e5773fca64d0 641 SUPERFAMILY SSF52096 6 296 5.91E-58 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c23670 00aba0ee259d4f299909e5773fca64d0 641 SUPERFAMILY SSF48179 583 638 1.45E-5 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c23670 00aba0ee259d4f299909e5773fca64d0 641 SUPERFAMILY SSF51735 303 480 8.26E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c38590 70a39ba9d323b2a45e74f8388394db6b 451 SUPERFAMILY SSF75304 8 450 6.41E-114 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MIM_c38590 70a39ba9d323b2a45e74f8388394db6b 451 Pfam PF01425 Amidase 26 439 9.5E-82 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MIM_c38590 70a39ba9d323b2a45e74f8388394db6b 451 Gene3D G3DSA:3.90.1300.10 8 450 5.5E-123 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MIM_c21090 5a8d24436d5bec6fb15afada4c2226d2 243 SUPERFAMILY SSF51261 83 207 3.03E-51 T 12-10-2018 IPR011055 Duplicated hybrid motif MIM_c21090 5a8d24436d5bec6fb15afada4c2226d2 243 Pfam PF01551 Peptidase family M23 109 206 1.2E-30 T 12-10-2018 IPR016047 Peptidase M23 MIM_c21090 5a8d24436d5bec6fb15afada4c2226d2 243 Gene3D G3DSA:2.70.70.10 72 211 1.9E-42 T 12-10-2018 IPR011055 Duplicated hybrid motif MIM_c24180 dc3b0084e2248da509f0f61c6cbe5a63 246 Pfam PF04060 Putative Fe-S cluster 14 46 7.7E-13 T 12-10-2018 IPR007202 4Fe-4S domain GO:0051536 MIM_c24180 dc3b0084e2248da509f0f61c6cbe5a63 246 SUPERFAMILY SSF54862 8 136 6.16E-28 T 12-10-2018 MIM_c24180 dc3b0084e2248da509f0f61c6cbe5a63 246 Pfam PF14697 4Fe-4S dicluster domain 79 133 2.7E-15 T 12-10-2018 MIM_c24180 dc3b0084e2248da509f0f61c6cbe5a63 246 Gene3D G3DSA:3.30.70.20 72 153 4.0E-19 T 12-10-2018 MIM_c24180 dc3b0084e2248da509f0f61c6cbe5a63 246 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 116 127 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MIM_c24180 dc3b0084e2248da509f0f61c6cbe5a63 246 Gene3D G3DSA:3.20.20.20 5 71 9.0E-13 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MIM_c24180 dc3b0084e2248da509f0f61c6cbe5a63 246 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 5 140 8.4E-61 T 12-10-2018 IPR010207 Ion-translocating oxidoreductase complex, RnfB/RsxB GO:0009055|GO:0051536 MIM_c37790 21fd51e53ac7c3359bf6d122678cbadb 424 Gene3D G3DSA:3.40.50.720 2 209 1.5E-66 T 12-10-2018 MIM_c37790 21fd51e53ac7c3359bf6d122678cbadb 424 PIRSF PIRSF500136 1 424 2.1E-150 T 12-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 MIM_c37790 21fd51e53ac7c3359bf6d122678cbadb 424 SMART SM00984 328 423 3.8E-17 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MIM_c37790 21fd51e53ac7c3359bf6d122678cbadb 424 SUPERFAMILY SSF51735 8 204 2.52E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c37790 21fd51e53ac7c3359bf6d122678cbadb 424 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 329 423 3.9E-17 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MIM_c37790 21fd51e53ac7c3359bf6d122678cbadb 424 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 9 419 6.5E-124 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MIM_c37790 21fd51e53ac7c3359bf6d122678cbadb 424 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 9 193 7.8E-59 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MIM_c37790 21fd51e53ac7c3359bf6d122678cbadb 424 PIRSF PIRSF000124 8 423 2.1E-80 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MIM_c37790 21fd51e53ac7c3359bf6d122678cbadb 424 SUPERFAMILY SSF48179 211 304 5.95E-30 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c37790 21fd51e53ac7c3359bf6d122678cbadb 424 SUPERFAMILY SSF52413 316 424 4.84E-23 T 12-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 MIM_c37790 21fd51e53ac7c3359bf6d122678cbadb 424 Gene3D G3DSA:3.40.50.720 210 424 1.6E-60 T 12-10-2018 MIM_c37790 21fd51e53ac7c3359bf6d122678cbadb 424 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 211 298 3.4E-28 T 12-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MIM_c39700 5f2aa79fc4c64af49433b41d1d1686ed 206 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 8 206 31.457 T 12-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c39700 5f2aa79fc4c64af49433b41d1d1686ed 206 Pfam PF00573 Ribosomal protein L4/L1 family 18 203 1.5E-62 T 12-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 MIM_c39700 5f2aa79fc4c64af49433b41d1d1686ed 206 Gene3D G3DSA:3.40.1370.10 3 206 2.5E-66 T 12-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 MIM_c39700 5f2aa79fc4c64af49433b41d1d1686ed 206 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 18 203 8.3E-70 T 12-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c39700 5f2aa79fc4c64af49433b41d1d1686ed 206 SUPERFAMILY SSF52166 1 206 1.44E-69 T 12-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 MIM_c23510 5a6b2134e947aa679fb9bbf0fe7c26e4 129 Gene3D G3DSA:3.20.80.10 1 129 2.0E-28 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily MIM_c23510 5a6b2134e947aa679fb9bbf0fe7c26e4 129 Pfam PF14526 Integron-associated effector binding protein 7 128 8.6E-10 T 12-10-2018 IPR029441 Integron-associated effector binding protein MIM_c23510 5a6b2134e947aa679fb9bbf0fe7c26e4 129 SMART SM00871 1 129 0.0022 T 12-10-2018 IPR010499 Bacterial transcription activator, effector binding MIM_c23510 5a6b2134e947aa679fb9bbf0fe7c26e4 129 SUPERFAMILY SSF55136 7 120 1.6E-8 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily MIM_c11650 044d686ab4a465287c6cee655765801b 117 Gene3D G3DSA:1.10.760.10 35 116 2.2E-17 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c11650 044d686ab4a465287c6cee655765801b 117 Pfam PF00034 Cytochrome c 47 117 3.6E-4 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c11650 044d686ab4a465287c6cee655765801b 117 SUPERFAMILY SSF46626 8 115 2.18E-16 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c38640 2697f3120f5f3226b6015ecdd4c02188 280 SUPERFAMILY SSF46689 165 213 4.93E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c38640 2697f3120f5f3226b6015ecdd4c02188 280 Pfam PF12833 Helix-turn-helix domain 185 263 5.5E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c38640 2697f3120f5f3226b6015ecdd4c02188 280 Gene3D G3DSA:1.10.10.60 213 269 2.4E-16 T 12-10-2018 MIM_c38640 2697f3120f5f3226b6015ecdd4c02188 280 Pfam PF00072 Response regulator receiver domain 16 124 6.7E-16 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c38640 2697f3120f5f3226b6015ecdd4c02188 280 SMART SM00342 179 262 5.6E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c38640 2697f3120f5f3226b6015ecdd4c02188 280 SMART SM00448 11 124 4.8E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c38640 2697f3120f5f3226b6015ecdd4c02188 280 SUPERFAMILY SSF46689 215 268 9.41E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c38640 2697f3120f5f3226b6015ecdd4c02188 280 SUPERFAMILY SSF52172 5 140 4.13E-27 T 12-10-2018 IPR011006 CheY-like superfamily MIM_c38640 2697f3120f5f3226b6015ecdd4c02188 280 Gene3D G3DSA:1.10.10.60 162 212 1.7E-9 T 12-10-2018 MIM_c38640 2697f3120f5f3226b6015ecdd4c02188 280 Gene3D G3DSA:3.40.50.2300 7 142 6.8E-23 T 12-10-2018 MIM_c34730 1e5b5bd49bf07b87bef26b8e3836429b 205 Pfam PF01613 Flavin reductase like domain 22 162 5.4E-16 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MIM_c34730 1e5b5bd49bf07b87bef26b8e3836429b 205 SUPERFAMILY SSF50475 6 194 1.62E-42 T 12-10-2018 MIM_c34730 1e5b5bd49bf07b87bef26b8e3836429b 205 SMART SM00903 19 171 1.5E-18 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MIM_c34730 1e5b5bd49bf07b87bef26b8e3836429b 205 Gene3D G3DSA:2.30.110.10 1 202 2.0E-60 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MIM_c20530 ec361f68a2745a61ce6b41b842d53c0c 609 Gene3D G3DSA:1.10.1040.10 163 294 5.7E-24 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MIM_c20530 ec361f68a2745a61ce6b41b842d53c0c 609 Gene3D G3DSA:1.10.1040.10 478 605 5.2E-26 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MIM_c20530 ec361f68a2745a61ce6b41b842d53c0c 609 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 281 9.5E-25 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MIM_c20530 ec361f68a2745a61ce6b41b842d53c0c 609 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 478 596 4.6E-23 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MIM_c20530 ec361f68a2745a61ce6b41b842d53c0c 609 Gene3D G3DSA:3.40.50.720 1 161 7.4E-50 T 12-10-2018 MIM_c20530 ec361f68a2745a61ce6b41b842d53c0c 609 Gene3D G3DSA:3.40.50.720 311 477 4.9E-49 T 12-10-2018 MIM_c20530 ec361f68a2745a61ce6b41b842d53c0c 609 SUPERFAMILY SSF51735 1 160 6.85E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c20530 ec361f68a2745a61ce6b41b842d53c0c 609 SUPERFAMILY SSF48179 163 292 1.7E-22 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c20530 ec361f68a2745a61ce6b41b842d53c0c 609 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 160 9.3E-42 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 MIM_c20530 ec361f68a2745a61ce6b41b842d53c0c 609 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 318 475 2.9E-39 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 MIM_c20530 ec361f68a2745a61ce6b41b842d53c0c 609 SUPERFAMILY SSF51735 317 476 2.68E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c20530 ec361f68a2745a61ce6b41b842d53c0c 609 SUPERFAMILY SSF48179 478 601 8.84E-24 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c03850 0c877aeceda6ef1190794fb1a4b72aee 229 SUPERFAMILY SSF161098 9 206 1.31E-40 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c03850 0c877aeceda6ef1190794fb1a4b72aee 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 220 3.9E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c03850 0c877aeceda6ef1190794fb1a4b72aee 229 Gene3D G3DSA:1.10.3720.10 1 223 3.6E-51 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c03850 0c877aeceda6ef1190794fb1a4b72aee 229 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 9 115 5.3E-19 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c26940 eedf802066441f52ed6fc3b64f3b576a 175 Gene3D G3DSA:2.60.40.1090 22 175 3.1E-35 T 12-10-2018 IPR036937 Fimbrial-type adhesion domain superfamily GO:0007155|GO:0009289 MIM_c26940 eedf802066441f52ed6fc3b64f3b576a 175 SUPERFAMILY SSF49401 25 175 2.93E-27 T 12-10-2018 IPR008966 Adhesion domain superfamily MIM_c26940 eedf802066441f52ed6fc3b64f3b576a 175 Pfam PF16970 Type-1 fimbrial protein, A 50 175 9.7E-15 T 12-10-2018 IPR039458 Type-1 fimbrial protein, A MIM_c15830 84e615758b74fe72e9e46b8d118b86fe 435 Pfam PF02601 Exonuclease VII, large subunit 118 427 3.3E-92 T 12-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 MIM_c15830 84e615758b74fe72e9e46b8d118b86fe 435 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 1 431 26.805 T 12-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 MIM_c15830 84e615758b74fe72e9e46b8d118b86fe 435 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 3 348 5.3E-125 T 12-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 MIM_c15830 84e615758b74fe72e9e46b8d118b86fe 435 Pfam PF13742 OB-fold nucleic acid binding domain 2 94 9.7E-29 T 12-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 MIM_c21660 c87eca76dffb297b096fc36c514f9286 303 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 135 152 1.2E-13 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MIM_c21660 c87eca76dffb297b096fc36c514f9286 303 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 162 175 1.2E-13 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MIM_c21660 c87eca76dffb297b096fc36c514f9286 303 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 85 96 1.2E-13 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MIM_c21660 c87eca76dffb297b096fc36c514f9286 303 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 57 279 7.9E-59 T 12-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 MIM_c21660 c87eca76dffb297b096fc36c514f9286 303 SUPERFAMILY SSF56601 6 297 1.88E-61 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MIM_c21660 c87eca76dffb297b096fc36c514f9286 303 Gene3D G3DSA:3.40.710.10 40 301 2.3E-68 T 12-10-2018 MIM_c28390 34409cb2781b51aed0eaf7d4aa1a56f3 352 Gene3D G3DSA:3.20.20.70 13 323 2.0E-127 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c28390 34409cb2781b51aed0eaf7d4aa1a56f3 352 SMART SM00729 52 264 1.2E-39 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MIM_c28390 34409cb2781b51aed0eaf7d4aa1a56f3 352 Hamap MF_01694 Biotin synthase [bioB]. 14 322 41.637 T 12-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MIM_c28390 34409cb2781b51aed0eaf7d4aa1a56f3 352 SMART SM00876 229 321 4.8E-46 T 12-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MIM_c28390 34409cb2781b51aed0eaf7d4aa1a56f3 352 SUPERFAMILY SSF102114 16 322 1.15E-93 T 12-10-2018 MIM_c28390 34409cb2781b51aed0eaf7d4aa1a56f3 352 TIGRFAM TIGR00433 bioB: biotin synthase 24 319 2.7E-123 T 12-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MIM_c28390 34409cb2781b51aed0eaf7d4aa1a56f3 352 PIRSF PIRSF001619 3 327 7.7E-133 T 12-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MIM_c28390 34409cb2781b51aed0eaf7d4aa1a56f3 352 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 229 319 6.4E-18 T 12-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MIM_c28390 34409cb2781b51aed0eaf7d4aa1a56f3 352 Pfam PF04055 Radical SAM superfamily 59 212 2.6E-18 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MIM_c22380 253147d57ca5e41d1b36541402682558 180 SUPERFAMILY SSF117856 15 157 9.68E-13 T 12-10-2018 MIM_c22380 253147d57ca5e41d1b36541402682558 180 Pfam PF03479 Domain of unknown function (DUF296) 18 127 5.7E-8 T 12-10-2018 IPR005175 PPC domain MIM_c22380 253147d57ca5e41d1b36541402682558 180 Gene3D G3DSA:3.30.1330.80 11 164 4.9E-9 T 12-10-2018 MIM_c03060 c85f9772ca5d1cdcee4234e733d6a893 584 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 12 179 2.2E-56 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MIM_c03060 c85f9772ca5d1cdcee4234e733d6a893 584 SUPERFAMILY SSF52518 383 574 1.02E-64 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c03060 c85f9772ca5d1cdcee4234e733d6a893 584 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 441 460 - T 12-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 MIM_c03060 c85f9772ca5d1cdcee4234e733d6a893 584 SUPERFAMILY SSF52467 202 371 3.47E-57 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MIM_c03060 c85f9772ca5d1cdcee4234e733d6a893 584 Gene3D G3DSA:3.40.50.970 3 187 1.1E-67 T 12-10-2018 MIM_c03060 c85f9772ca5d1cdcee4234e733d6a893 584 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 205 342 1.6E-39 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MIM_c03060 c85f9772ca5d1cdcee4234e733d6a893 584 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 12 575 2.8E-215 T 12-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MIM_c03060 c85f9772ca5d1cdcee4234e733d6a893 584 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 404 552 1.2E-49 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MIM_c03060 c85f9772ca5d1cdcee4234e733d6a893 584 Gene3D G3DSA:3.40.50.1220 198 369 3.9E-55 T 12-10-2018 MIM_c03060 c85f9772ca5d1cdcee4234e733d6a893 584 SUPERFAMILY SSF52518 8 179 2.22E-59 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c03060 c85f9772ca5d1cdcee4234e733d6a893 584 Gene3D G3DSA:3.40.50.970 375 581 1.7E-68 T 12-10-2018 MIM_c21070 a2d9dd2302de37c1296f9a7a8fd406c6 268 Pfam PF00248 Aldo/keto reductase family 8 250 1.7E-50 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain MIM_c21070 a2d9dd2302de37c1296f9a7a8fd406c6 268 SUPERFAMILY SSF51430 2 257 4.06E-83 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MIM_c21070 a2d9dd2302de37c1296f9a7a8fd406c6 268 Gene3D G3DSA:3.20.20.100 1 268 5.4E-95 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MIM_c21070 a2d9dd2302de37c1296f9a7a8fd406c6 268 PIRSF PIRSF000097 1 266 1.4E-68 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MIM_c21070 a2d9dd2302de37c1296f9a7a8fd406c6 268 PRINTS PR00069 Aldo-keto reductase signature 25 49 7.0E-47 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MIM_c21070 a2d9dd2302de37c1296f9a7a8fd406c6 268 PRINTS PR00069 Aldo-keto reductase signature 149 178 7.0E-47 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MIM_c21070 a2d9dd2302de37c1296f9a7a8fd406c6 268 PRINTS PR00069 Aldo-keto reductase signature 186 210 7.0E-47 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MIM_c21070 a2d9dd2302de37c1296f9a7a8fd406c6 268 PRINTS PR00069 Aldo-keto reductase signature 81 99 7.0E-47 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MIM_c21070 a2d9dd2302de37c1296f9a7a8fd406c6 268 PRINTS PR00069 Aldo-keto reductase signature 114 131 7.0E-47 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MIM_c21070 a2d9dd2302de37c1296f9a7a8fd406c6 268 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 29 46 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MIM_c21070 a2d9dd2302de37c1296f9a7a8fd406c6 268 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 114 131 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MIM_c39770 2e4b292b8cce846ed83737efc3c1b97f 336 Pfam PF02653 Branched-chain amino acid transport system / permease component 42 317 6.3E-27 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c28380 d25108204bba4296b1ff3d27eb396704 262 TIGRFAM TIGR01096 3A0103s03R: lysine-arginine-ornithine-binding periplasmic protein 11 255 5.2E-80 T 12-10-2018 IPR005768 Specific amino acids and opine-binding periplasmic protein, ABC transporter GO:0030288|GO:0071705 MIM_c28380 d25108204bba4296b1ff3d27eb396704 262 SMART SM00062 29 258 5.6E-72 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c28380 d25108204bba4296b1ff3d27eb396704 262 Gene3D G3DSA:3.40.190.10 115 214 1.0E-75 T 12-10-2018 MIM_c28380 d25108204bba4296b1ff3d27eb396704 262 Gene3D G3DSA:3.40.190.10 33 255 1.0E-75 T 12-10-2018 MIM_c28380 d25108204bba4296b1ff3d27eb396704 262 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 52 65 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site MIM_c28380 d25108204bba4296b1ff3d27eb396704 262 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 30 256 1.1E-65 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c28380 d25108204bba4296b1ff3d27eb396704 262 SUPERFAMILY SSF53850 10 259 2.11E-69 T 12-10-2018 MIM_c00970 09f3da76e397c9a8f64a796f233ec98d 557 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c00970 09f3da76e397c9a8f64a796f233ec98d 557 SUPERFAMILY SSF52540 2 253 4.14E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c00970 09f3da76e397c9a8f64a796f233ec98d 557 SUPERFAMILY SSF52540 279 516 1.02E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c00970 09f3da76e397c9a8f64a796f233ec98d 557 ProSitePatterns PS00211 ABC transporters family signature. 452 466 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c00970 09f3da76e397c9a8f64a796f233ec98d 557 Pfam PF00005 ABC transporter 339 480 8.7E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c00970 09f3da76e397c9a8f64a796f233ec98d 557 Pfam PF12848 ABC transporter 217 298 3.4E-28 T 12-10-2018 IPR032781 ABC-transporter extension domain MIM_c00970 09f3da76e397c9a8f64a796f233ec98d 557 SMART SM00382 347 525 1.0E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c00970 09f3da76e397c9a8f64a796f233ec98d 557 SMART SM00382 26 223 4.8E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c00970 09f3da76e397c9a8f64a796f233ec98d 557 Gene3D G3DSA:3.40.50.300 1 259 8.0E-58 T 12-10-2018 MIM_c00970 09f3da76e397c9a8f64a796f233ec98d 557 Gene3D G3DSA:3.40.50.300 275 556 1.1E-49 T 12-10-2018 MIM_c00970 09f3da76e397c9a8f64a796f233ec98d 557 Pfam PF00005 ABC transporter 17 178 7.2E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c33900 bddb632e2e59b87c80af5257dff1ba9d 239 SUPERFAMILY SSF52540 11 210 8.21E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c33900 bddb632e2e59b87c80af5257dff1ba9d 239 ProSitePatterns PS00211 ABC transporters family signature. 125 139 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c33900 bddb632e2e59b87c80af5257dff1ba9d 239 Pfam PF00005 ABC transporter 27 153 7.1E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c33900 bddb632e2e59b87c80af5257dff1ba9d 239 Gene3D G3DSA:3.40.50.300 3 232 2.6E-57 T 12-10-2018 MIM_c33900 bddb632e2e59b87c80af5257dff1ba9d 239 SMART SM00382 35 202 6.4E-19 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c38210 61eb424a52d86e16096d2a2937bbddf2 443 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 68 1.1E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c38210 61eb424a52d86e16096d2a2937bbddf2 443 Gene3D G3DSA:3.90.1150.10 87 436 1.8E-66 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c38210 61eb424a52d86e16096d2a2937bbddf2 443 Gene3D G3DSA:3.40.640.10 123 338 1.8E-66 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c38210 61eb424a52d86e16096d2a2937bbddf2 443 Pfam PF00155 Aminotransferase class I and II 87 434 6.7E-30 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MIM_c38210 61eb424a52d86e16096d2a2937bbddf2 443 SUPERFAMILY SSF46785 5 72 8.93E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c38210 61eb424a52d86e16096d2a2937bbddf2 443 SUPERFAMILY SSF53383 85 438 5.91E-75 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c38210 61eb424a52d86e16096d2a2937bbddf2 443 Gene3D G3DSA:1.10.10.10 2 69 1.9E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c38210 61eb424a52d86e16096d2a2937bbddf2 443 SMART SM00345 9 68 3.4E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c28490 8e033fc723e88ac8b3170d053014d2e4 402 Gene3D G3DSA:3.90.105.10 21 168 1.2E-125 T 12-10-2018 MIM_c28490 8e033fc723e88ac8b3170d053014d2e4 402 Pfam PF03453 MoeA N-terminal region (domain I and II) 5 161 1.3E-39 T 12-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MIM_c28490 8e033fc723e88ac8b3170d053014d2e4 402 SUPERFAMILY SSF53218 171 316 3.66E-40 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily MIM_c28490 8e033fc723e88ac8b3170d053014d2e4 402 Gene3D G3DSA:2.40.340.10 322 391 1.2E-125 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MIM_c28490 8e033fc723e88ac8b3170d053014d2e4 402 Gene3D G3DSA:2.170.190.11 45 135 1.2E-125 T 12-10-2018 MIM_c28490 8e033fc723e88ac8b3170d053014d2e4 402 Pfam PF00994 Probable molybdopterin binding domain 174 311 1.3E-27 T 12-10-2018 IPR001453 MoaB/Mog domain MIM_c28490 8e033fc723e88ac8b3170d053014d2e4 402 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 171 308 3.2E-29 T 12-10-2018 IPR001453 MoaB/Mog domain MIM_c28490 8e033fc723e88ac8b3170d053014d2e4 402 SUPERFAMILY SSF63882 1 169 8.24E-52 T 12-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MIM_c28490 8e033fc723e88ac8b3170d053014d2e4 402 Gene3D G3DSA:3.40.980.10 169 321 1.2E-125 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily MIM_c28490 8e033fc723e88ac8b3170d053014d2e4 402 SMART SM00852 174 312 1.6E-40 T 12-10-2018 IPR001453 MoaB/Mog domain MIM_c28490 8e033fc723e88ac8b3170d053014d2e4 402 SUPERFAMILY SSF63867 321 396 7.72E-12 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MIM_c28490 8e033fc723e88ac8b3170d053014d2e4 402 Pfam PF03454 MoeA C-terminal region (domain IV) 326 396 2.9E-10 T 12-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MIM_c06430 d82bd06b9ed30e3d7f1cf4b858e5e4fe 326 SUPERFAMILY SSF103481 42 144 1.96E-14 T 12-10-2018 MIM_c06430 d82bd06b9ed30e3d7f1cf4b858e5e4fe 326 Pfam PF00892 EamA-like transporter family 11 142 4.4E-13 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MIM_c06430 d82bd06b9ed30e3d7f1cf4b858e5e4fe 326 Pfam PF00892 EamA-like transporter family 158 282 1.6E-20 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MIM_c06430 d82bd06b9ed30e3d7f1cf4b858e5e4fe 326 SUPERFAMILY SSF103481 191 288 6.67E-17 T 12-10-2018 MIM_c02910 939dbb1dd3fd5a33560ea29cca64ea94 143 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 130 1.7E-10 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MIM_c02910 939dbb1dd3fd5a33560ea29cca64ea94 143 SUPERFAMILY SSF54593 7 136 6.05E-28 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c02910 939dbb1dd3fd5a33560ea29cca64ea94 143 Gene3D G3DSA:3.10.180.10 3 142 1.3E-50 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c34480 8c072007b7557db29b77a32b242a8954 290 SUPERFAMILY SSF53474 28 286 5.56E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c34480 8c072007b7557db29b77a32b242a8954 290 Gene3D G3DSA:3.40.50.1820 14 287 5.5E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c34480 8c072007b7557db29b77a32b242a8954 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 122 135 1.1E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c34480 8c072007b7557db29b77a32b242a8954 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 78 93 1.1E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c34480 8c072007b7557db29b77a32b242a8954 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 136 149 1.1E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c34480 8c072007b7557db29b77a32b242a8954 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 230 244 1.1E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c34480 8c072007b7557db29b77a32b242a8954 290 Pfam PF12146 Serine aminopeptidase, S33 54 273 1.6E-14 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 MIM_c26060 b26ee1d41a1460537404a2c0e6b0aa20 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c26060 b26ee1d41a1460537404a2c0e6b0aa20 250 Gene3D G3DSA:3.40.50.720 2 246 1.9E-50 T 12-10-2018 MIM_c26060 b26ee1d41a1460537404a2c0e6b0aa20 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 1.2E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c26060 b26ee1d41a1460537404a2c0e6b0aa20 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 1.2E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c26060 b26ee1d41a1460537404a2c0e6b0aa20 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 1.2E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c26060 b26ee1d41a1460537404a2c0e6b0aa20 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 1.2E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c26060 b26ee1d41a1460537404a2c0e6b0aa20 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 1.2E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c26060 b26ee1d41a1460537404a2c0e6b0aa20 250 SUPERFAMILY SSF51735 3 242 7.63E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c26060 b26ee1d41a1460537404a2c0e6b0aa20 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 1.8E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c26060 b26ee1d41a1460537404a2c0e6b0aa20 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 1.8E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c26060 b26ee1d41a1460537404a2c0e6b0aa20 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 1.8E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c26060 b26ee1d41a1460537404a2c0e6b0aa20 250 Pfam PF00106 short chain dehydrogenase 3 186 6.7E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01660 8a42a0000f99fe9c4c2f0b00787a7573 215 SMART SM00987 43 207 1.2E-22 T 12-10-2018 MIM_c01660 8a42a0000f99fe9c4c2f0b00787a7573 215 Pfam PF03167 Uracil DNA glycosylase superfamily 46 206 8.4E-20 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MIM_c01660 8a42a0000f99fe9c4c2f0b00787a7573 215 SMART SM00986 43 207 1.2E-22 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MIM_c01660 8a42a0000f99fe9c4c2f0b00787a7573 215 Gene3D G3DSA:3.40.470.10 9 215 3.1E-62 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MIM_c01660 8a42a0000f99fe9c4c2f0b00787a7573 215 SUPERFAMILY SSF52141 13 213 8.83E-46 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MIM_c32160 192a845a2d3af4065d917954a9e56c71 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 237 386 1.2E-42 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MIM_c32160 192a845a2d3af4065d917954a9e56c71 389 SUPERFAMILY SSF47203 237 388 2.74E-46 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c32160 192a845a2d3af4065d917954a9e56c71 389 Gene3D G3DSA:2.40.110.10 131 242 1.4E-40 T 12-10-2018 MIM_c32160 192a845a2d3af4065d917954a9e56c71 389 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 134 146 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MIM_c32160 192a845a2d3af4065d917954a9e56c71 389 Gene3D G3DSA:1.20.140.10 243 389 2.0E-43 T 12-10-2018 MIM_c32160 192a845a2d3af4065d917954a9e56c71 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 132 213 1.3E-18 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MIM_c32160 192a845a2d3af4065d917954a9e56c71 389 SUPERFAMILY SSF56645 11 248 3.93E-57 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c32160 192a845a2d3af4065d917954a9e56c71 389 Gene3D G3DSA:1.10.540.10 8 129 7.7E-26 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c32160 192a845a2d3af4065d917954a9e56c71 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 13 128 3.3E-12 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c21810 6ebde825ed072128ebc392cc0757d121 801 Gene3D G3DSA:3.50.40.10 197 395 9.2E-70 T 12-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 MIM_c21810 6ebde825ed072128ebc392cc0757d121 801 Gene3D G3DSA:3.30.70.380 704 801 2.0E-16 T 12-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 MIM_c21810 6ebde825ed072128ebc392cc0757d121 801 Pfam PF03484 tRNA synthetase B5 domain 404 469 1.3E-18 T 12-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 MIM_c21810 6ebde825ed072128ebc392cc0757d121 801 Pfam PF01588 Putative tRNA binding domain 45 145 2.5E-24 T 12-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 MIM_c21810 6ebde825ed072128ebc392cc0757d121 801 SUPERFAMILY SSF50249 38 195 2.69E-49 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c21810 6ebde825ed072128ebc392cc0757d121 801 Gene3D G3DSA:3.30.930.10 484 693 2.1E-54 T 12-10-2018 MIM_c21810 6ebde825ed072128ebc392cc0757d121 801 SMART SM00873 212 385 5.8E-80 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 MIM_c21810 6ebde825ed072128ebc392cc0757d121 801 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 795 42.755 T 12-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MIM_c21810 6ebde825ed072128ebc392cc0757d121 801 Gene3D G3DSA:2.40.50.140 39 154 2.8E-71 T 12-10-2018 MIM_c21810 6ebde825ed072128ebc392cc0757d121 801 Gene3D G3DSA:3.30.56.10 399 473 8.4E-26 T 12-10-2018 MIM_c21810 6ebde825ed072128ebc392cc0757d121 801 SMART SM00896 703 801 3.1E-23 T 12-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 MIM_c21810 6ebde825ed072128ebc392cc0757d121 801 SUPERFAMILY SSF55681 465 692 1.89E-47 T 12-10-2018 MIM_c21810 6ebde825ed072128ebc392cc0757d121 801 Gene3D G3DSA:3.30.56.10 5 181 2.8E-71 T 12-10-2018 MIM_c21810 6ebde825ed072128ebc392cc0757d121 801 Pfam PF03147 Ferredoxin-fold anticodon binding domain 704 801 2.6E-21 T 12-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 MIM_c21810 6ebde825ed072128ebc392cc0757d121 801 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 801 6.6E-233 T 12-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MIM_c21810 6ebde825ed072128ebc392cc0757d121 801 SUPERFAMILY SSF54991 698 801 4.45E-20 T 12-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 MIM_c21810 6ebde825ed072128ebc392cc0757d121 801 Pfam PF03483 B3/4 domain 213 385 2.5E-60 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 MIM_c21810 6ebde825ed072128ebc392cc0757d121 801 SMART SM00874 401 469 1.6E-27 T 12-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 MIM_c21810 6ebde825ed072128ebc392cc0757d121 801 SUPERFAMILY SSF56037 195 391 3.92E-67 T 12-10-2018 MIM_c21810 6ebde825ed072128ebc392cc0757d121 801 SUPERFAMILY SSF46955 403 473 4.21E-19 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily MIM_c24480 8f0389da0fba50e1d6fa4cc2ec35fa19 688 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 74 131 5.4E-23 T 12-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24480 8f0389da0fba50e1d6fa4cc2ec35fa19 688 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 167 188 1.9E-65 T 12-10-2018 MIM_c24480 8f0389da0fba50e1d6fa4cc2ec35fa19 688 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 262 288 1.9E-65 T 12-10-2018 MIM_c24480 8f0389da0fba50e1d6fa4cc2ec35fa19 688 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 120 140 1.9E-65 T 12-10-2018 MIM_c24480 8f0389da0fba50e1d6fa4cc2ec35fa19 688 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 435 454 1.9E-65 T 12-10-2018 MIM_c24480 8f0389da0fba50e1d6fa4cc2ec35fa19 688 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 92 117 1.9E-65 T 12-10-2018 MIM_c24480 8f0389da0fba50e1d6fa4cc2ec35fa19 688 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 240 261 1.9E-65 T 12-10-2018 MIM_c24480 8f0389da0fba50e1d6fa4cc2ec35fa19 688 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 330 342 1.9E-65 T 12-10-2018 MIM_c24480 8f0389da0fba50e1d6fa4cc2ec35fa19 688 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 504 525 1.6E-15 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 MIM_c24480 8f0389da0fba50e1d6fa4cc2ec35fa19 688 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 68 92 1.6E-15 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 MIM_c24480 8f0389da0fba50e1d6fa4cc2ec35fa19 688 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 280 302 1.6E-15 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 MIM_c24480 8f0389da0fba50e1d6fa4cc2ec35fa19 688 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 434 456 1.6E-15 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 MIM_c24480 8f0389da0fba50e1d6fa4cc2ec35fa19 688 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 94 114 1.6E-15 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 MIM_c24480 8f0389da0fba50e1d6fa4cc2ec35fa19 688 Pfam PF00361 Proton-conducting membrane transporter 143 432 8.2E-87 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24480 8f0389da0fba50e1d6fa4cc2ec35fa19 688 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 9 684 2.7E-239 T 12-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c38200 b8045f00487f8d8ac599e7a71fdb57af 384 Gene3D G3DSA:3.40.640.10 6 248 7.1E-72 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c38200 b8045f00487f8d8ac599e7a71fdb57af 384 PIRSF PIRSF001434 2 380 1.5E-114 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MIM_c38200 b8045f00487f8d8ac599e7a71fdb57af 384 SUPERFAMILY SSF53383 17 377 1.9E-87 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c38200 b8045f00487f8d8ac599e7a71fdb57af 384 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 190 204 - T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MIM_c38200 b8045f00487f8d8ac599e7a71fdb57af 384 Gene3D G3DSA:3.90.1150.10 249 379 6.1E-32 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c38200 b8045f00487f8d8ac599e7a71fdb57af 384 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 11 376 1.4E-98 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MIM_c08650 38b9fb5e41dcf269e964d8e22d2c0037 373 Pfam PF01266 FAD dependent oxidoreductase 5 337 2.9E-53 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MIM_c08650 38b9fb5e41dcf269e964d8e22d2c0037 373 SUPERFAMILY SSF54373 227 310 1.14E-11 T 12-10-2018 MIM_c08650 38b9fb5e41dcf269e964d8e22d2c0037 373 SUPERFAMILY SSF51905 4 368 1.64E-51 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c08650 38b9fb5e41dcf269e964d8e22d2c0037 373 Gene3D G3DSA:3.50.50.60 5 338 1.7E-81 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c08650 38b9fb5e41dcf269e964d8e22d2c0037 373 Gene3D G3DSA:3.30.9.10 91 309 1.7E-81 T 12-10-2018 MIM_c35970 755a89c4ce967e258f6fbcbf4610064f 337 Pfam PF13343 Bacterial extracellular solute-binding protein 76 320 5.6E-49 T 12-10-2018 MIM_c35970 755a89c4ce967e258f6fbcbf4610064f 337 Gene3D G3DSA:3.40.190.10 129 318 6.2E-56 T 12-10-2018 MIM_c35970 755a89c4ce967e258f6fbcbf4610064f 337 SUPERFAMILY SSF53850 35 331 2.98E-62 T 12-10-2018 MIM_c35970 755a89c4ce967e258f6fbcbf4610064f 337 Gene3D G3DSA:3.40.190.10 45 307 6.2E-56 T 12-10-2018 MIM_c31270 7b98944983a1f265ba16418371598740 118 Pfam PF06532 Protein of unknown function (DUF1109) 10 111 8.1E-15 T 12-10-2018 IPR009495 Anti-sigma-F factor NrsF MIM_c39200 6ebc1e72fe9705c884087f8b6f6a2b3e 471 Pfam PF00512 His Kinase A (phospho-acceptor) domain 244 305 2.2E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MIM_c39200 6ebc1e72fe9705c884087f8b6f6a2b3e 471 Gene3D G3DSA:3.30.565.10 316 469 1.2E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c39200 6ebc1e72fe9705c884087f8b6f6a2b3e 471 SMART SM00388 243 308 2.1E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MIM_c39200 6ebc1e72fe9705c884087f8b6f6a2b3e 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 409 7.8E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c39200 6ebc1e72fe9705c884087f8b6f6a2b3e 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 446 7.8E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c39200 6ebc1e72fe9705c884087f8b6f6a2b3e 471 SUPERFAMILY SSF55874 313 465 9.69E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c39200 6ebc1e72fe9705c884087f8b6f6a2b3e 471 SMART SM00387 357 469 1.7E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c39200 6ebc1e72fe9705c884087f8b6f6a2b3e 471 Pfam PF08521 Two-component sensor kinase N-terminal 20 164 2.4E-25 T 12-10-2018 IPR013727 Two-component sensor kinase, N-terminal MIM_c39200 6ebc1e72fe9705c884087f8b6f6a2b3e 471 Gene3D G3DSA:1.10.287.130 194 308 5.0E-17 T 12-10-2018 MIM_c39200 6ebc1e72fe9705c884087f8b6f6a2b3e 471 SUPERFAMILY SSF47384 226 306 2.35E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MIM_c39200 6ebc1e72fe9705c884087f8b6f6a2b3e 471 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 362 465 5.5E-13 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c31810 c95f6b88e6cab60e1864fe171087ca82 501 Gene3D G3DSA:1.10.10.10 14 92 4.1E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c31810 c95f6b88e6cab60e1864fe171087ca82 501 Pfam PF00155 Aminotransferase class I and II 145 453 1.4E-17 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MIM_c31810 c95f6b88e6cab60e1864fe171087ca82 501 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 60 7.4E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c31810 c95f6b88e6cab60e1864fe171087ca82 501 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 60 76 7.4E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c31810 c95f6b88e6cab60e1864fe171087ca82 501 Gene3D G3DSA:3.40.640.10 122 485 8.3E-107 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c31810 c95f6b88e6cab60e1864fe171087ca82 501 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 86 2.8E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c31810 c95f6b88e6cab60e1864fe171087ca82 501 SUPERFAMILY SSF46785 23 87 1.18E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c31810 c95f6b88e6cab60e1864fe171087ca82 501 SUPERFAMILY SSF53383 111 491 3.94E-82 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c31810 c95f6b88e6cab60e1864fe171087ca82 501 SMART SM00345 27 86 4.3E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c19030 8b3c8786d327d4bc5cc3936b6d92b75e 373 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 258 276 8.6E-38 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MIM_c19030 8b3c8786d327d4bc5cc3936b6d92b75e 373 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 29 45 8.6E-38 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MIM_c19030 8b3c8786d327d4bc5cc3936b6d92b75e 373 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 70 88 8.6E-38 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MIM_c19030 8b3c8786d327d4bc5cc3936b6d92b75e 373 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 91 101 8.6E-38 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MIM_c19030 8b3c8786d327d4bc5cc3936b6d92b75e 373 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 51 67 8.6E-38 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MIM_c19030 8b3c8786d327d4bc5cc3936b6d92b75e 373 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 281 294 8.6E-38 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MIM_c19030 8b3c8786d327d4bc5cc3936b6d92b75e 373 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 333 348 8.6E-38 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MIM_c19030 8b3c8786d327d4bc5cc3936b6d92b75e 373 Gene3D G3DSA:3.40.50.2300 148 276 5.9E-110 T 12-10-2018 MIM_c19030 8b3c8786d327d4bc5cc3936b6d92b75e 373 Pfam PF13458 Periplasmic binding protein 28 367 9.0E-61 T 12-10-2018 IPR028081 Leucine-binding protein domain MIM_c19030 8b3c8786d327d4bc5cc3936b6d92b75e 373 Gene3D G3DSA:3.40.50.2300 30 349 5.9E-110 T 12-10-2018 MIM_c19030 8b3c8786d327d4bc5cc3936b6d92b75e 373 SUPERFAMILY SSF53822 27 368 8.07E-90 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c08560 0daad0f694d457bd2af6b9c7037f4116 398 Gene3D G3DSA:3.40.50.10540 3 392 7.2E-126 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c08560 0daad0f694d457bd2af6b9c7037f4116 398 Pfam PF02515 CoA-transferase family III 4 374 5.3E-114 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 MIM_c08560 0daad0f694d457bd2af6b9c7037f4116 398 Gene3D G3DSA:3.30.1540.10 234 325 7.2E-126 T 12-10-2018 MIM_c08560 0daad0f694d457bd2af6b9c7037f4116 398 SUPERFAMILY SSF89796 1 398 8.11E-126 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c30250 0eb55ea6789f12ec179e1d7ccfd798fd 189 SUPERFAMILY SSF109604 21 69 6.65E-7 T 12-10-2018 MIM_c30250 0eb55ea6789f12ec179e1d7ccfd798fd 189 Gene3D G3DSA:1.10.3210.10 2 185 2.6E-58 T 12-10-2018 MIM_c30250 0eb55ea6789f12ec179e1d7ccfd798fd 189 Pfam PF01966 HD domain 29 74 1.1E-4 T 12-10-2018 IPR006674 HD domain MIM_c30250 0eb55ea6789f12ec179e1d7ccfd798fd 189 TIGRFAM TIGR03276 Phn-HD: phosphonate degradation operons associated HDIG domain protein 5 180 7.5E-69 T 12-10-2018 IPR017670 Phosphonate degradation operon associated HDIG domain protein MIM_c31170 b8062d43b8f253db9c97729c6b2f7b12 404 SUPERFAMILY SSF103473 19 398 1.7E-53 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c31170 b8062d43b8f253db9c97729c6b2f7b12 404 Gene3D G3DSA:1.20.1250.20 22 400 1.3E-41 T 12-10-2018 MIM_c31170 b8062d43b8f253db9c97729c6b2f7b12 404 Pfam PF07690 Major Facilitator Superfamily 33 345 1.5E-23 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c07120 f9a219ebeadb3b44683aaa96316fedc6 303 Pfam PF00682 HMGL-like 6 279 9.4E-59 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 MIM_c07120 f9a219ebeadb3b44683aaa96316fedc6 303 SUPERFAMILY SSF51569 3 289 6.59E-77 T 12-10-2018 MIM_c07120 f9a219ebeadb3b44683aaa96316fedc6 303 Gene3D G3DSA:3.20.20.70 1 300 9.5E-135 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c31850 f84871d5358f0d4663b387e918bfd113 352 PIRSF PIRSF500176 24 352 3.6E-80 T 12-10-2018 MIM_c31850 f84871d5358f0d4663b387e918bfd113 352 PRINTS PR00139 Asparaginase/glutaminase family signature 105 123 1.7E-14 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c31850 f84871d5358f0d4663b387e918bfd113 352 PRINTS PR00139 Asparaginase/glutaminase family signature 28 39 1.7E-14 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c31850 f84871d5358f0d4663b387e918bfd113 352 PRINTS PR00139 Asparaginase/glutaminase family signature 281 299 1.7E-14 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c31850 f84871d5358f0d4663b387e918bfd113 352 SUPERFAMILY SSF53774 23 352 1.24E-92 T 12-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 MIM_c31850 f84871d5358f0d4663b387e918bfd113 352 Gene3D G3DSA:3.40.50.1170 22 234 5.3E-67 T 12-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 MIM_c31850 f84871d5358f0d4663b387e918bfd113 352 Gene3D G3DSA:3.40.50.40 235 352 3.0E-30 T 12-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 MIM_c31850 f84871d5358f0d4663b387e918bfd113 352 Pfam PF00710 Asparaginase, N-terminal 28 216 1.4E-54 T 12-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 MIM_c31850 f84871d5358f0d4663b387e918bfd113 352 PIRSF PIRSF001220 22 352 1.6E-86 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c31850 f84871d5358f0d4663b387e918bfd113 352 SMART SM00870 27 346 1.6E-111 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MIM_c01870 54ca63bbee0c5cf81255fc832c49dff2 199 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 59 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MIM_c01870 54ca63bbee0c5cf81255fc832c49dff2 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 4.8E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c01870 54ca63bbee0c5cf81255fc832c49dff2 199 Gene3D G3DSA:1.10.357.10 53 193 7.5E-18 T 12-10-2018 MIM_c01870 54ca63bbee0c5cf81255fc832c49dff2 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 7.3E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c01870 54ca63bbee0c5cf81255fc832c49dff2 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 7.3E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c01870 54ca63bbee0c5cf81255fc832c49dff2 199 SUPERFAMILY SSF46689 3 76 9.75E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c01870 54ca63bbee0c5cf81255fc832c49dff2 199 Gene3D G3DSA:1.10.10.60 6 52 3.4E-20 T 12-10-2018 MIM_c30580 7b5dfc73729a72bcbd0741c7becf8459 531 SUPERFAMILY SSF53850 29 525 1.18E-99 T 12-10-2018 MIM_c30580 7b5dfc73729a72bcbd0741c7becf8459 531 Gene3D G3DSA:3.10.105.10 278 505 2.5E-85 T 12-10-2018 MIM_c30580 7b5dfc73729a72bcbd0741c7becf8459 531 PIRSF PIRSF002741 4 530 6.1E-60 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MIM_c30580 7b5dfc73729a72bcbd0741c7becf8459 531 Gene3D G3DSA:3.90.76.10 45 190 2.5E-85 T 12-10-2018 MIM_c30580 7b5dfc73729a72bcbd0741c7becf8459 531 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 75 449 1.3E-73 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain MIM_c30580 7b5dfc73729a72bcbd0741c7becf8459 531 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 81 102 - T 12-10-2018 IPR023765 Solute-binding protein family 5, conserved site MIM_c30580 7b5dfc73729a72bcbd0741c7becf8459 531 Gene3D G3DSA:3.40.190.10 191 513 2.5E-85 T 12-10-2018 MIM_c15960 74510cb43cd5c7a3a850bed382f438b2 207 Pfam PF09335 SNARE associated Golgi protein 39 163 7.8E-13 T 12-10-2018 IPR032816 SNARE associated Golgi protein MIM_c19120 7f3e73f98e27a90ab0251c53bb5c6dce 255 Pfam PF00005 ABC transporter 22 181 2.7E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c19120 7f3e73f98e27a90ab0251c53bb5c6dce 255 SMART SM00382 30 231 7.1E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c19120 7f3e73f98e27a90ab0251c53bb5c6dce 255 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 232 253 2.5E-8 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal MIM_c19120 7f3e73f98e27a90ab0251c53bb5c6dce 255 SUPERFAMILY SSF52540 4 253 7.72E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c19120 7f3e73f98e27a90ab0251c53bb5c6dce 255 Gene3D G3DSA:3.40.50.300 3 254 5.3E-59 T 12-10-2018 MIM_c09440 c0577d53527c8166a7edc10b01664ffa 110 Pfam PF00355 Rieske [2Fe-2S] domain 6 86 7.0E-17 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MIM_c09440 c0577d53527c8166a7edc10b01664ffa 110 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 6 105 3.4E-25 T 12-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 MIM_c09440 c0577d53527c8166a7edc10b01664ffa 110 SUPERFAMILY SSF50022 6 108 1.02E-30 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MIM_c09440 c0577d53527c8166a7edc10b01664ffa 110 Gene3D G3DSA:2.102.10.10 3 109 5.6E-28 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MIM_c30060 708997406c1c58a3d73b94e5417a07c1 216 Pfam PF09335 SNARE associated Golgi protein 47 170 3.6E-24 T 12-10-2018 IPR032816 SNARE associated Golgi protein MIM_c33250 9f19012aeff1c8a582022e804c94c94e 305 SUPERFAMILY SSF46689 186 232 4.3E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c33250 9f19012aeff1c8a582022e804c94c94e 305 Pfam PF12833 Helix-turn-helix domain 205 282 7.0E-17 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c33250 9f19012aeff1c8a582022e804c94c94e 305 SUPERFAMILY SSF46689 236 283 2.69E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c33250 9f19012aeff1c8a582022e804c94c94e 305 SMART SM00342 199 282 9.5E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c33250 9f19012aeff1c8a582022e804c94c94e 305 Gene3D G3DSA:1.10.10.60 180 290 1.3E-25 T 12-10-2018 MIM_c05960 f7a6e0ea322bd6ad0992492846a0d69b 268 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 98 106 - T 12-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MIM_c05960 f7a6e0ea322bd6ad0992492846a0d69b 268 Pfam PF01177 Asp/Glu/Hydantoin racemase 26 244 9.1E-52 T 12-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MIM_c05960 f7a6e0ea322bd6ad0992492846a0d69b 268 SUPERFAMILY SSF53681 22 134 7.85E-31 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MIM_c05960 f7a6e0ea322bd6ad0992492846a0d69b 268 TIGRFAM TIGR00035 asp_race: aspartate racemase 22 223 4.3E-37 T 12-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 MIM_c05960 f7a6e0ea322bd6ad0992492846a0d69b 268 Gene3D G3DSA:3.40.50.1860 124 237 2.1E-66 T 12-10-2018 MIM_c05960 f7a6e0ea322bd6ad0992492846a0d69b 268 Gene3D G3DSA:3.40.50.1860 23 242 2.1E-66 T 12-10-2018 MIM_c05960 f7a6e0ea322bd6ad0992492846a0d69b 268 SUPERFAMILY SSF53681 139 247 4.58E-18 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MIM_c29580 3ed40dd3612402c869ac193cb026d27e 54 Pfam PF00301 Rubredoxin 4 49 1.2E-22 T 12-10-2018 IPR024935 Rubredoxin domain GO:0005506 MIM_c29580 3ed40dd3612402c869ac193cb026d27e 54 PRINTS PR00163 Rubredoxin signature 33 49 2.5E-8 T 12-10-2018 IPR024935 Rubredoxin domain GO:0005506 MIM_c29580 3ed40dd3612402c869ac193cb026d27e 54 PRINTS PR00163 Rubredoxin signature 3 19 2.5E-8 T 12-10-2018 IPR024935 Rubredoxin domain GO:0005506 MIM_c29580 3ed40dd3612402c869ac193cb026d27e 54 Gene3D G3DSA:2.20.28.10 1 54 3.6E-27 T 12-10-2018 MIM_c29580 3ed40dd3612402c869ac193cb026d27e 54 SUPERFAMILY SSF57802 1 53 2.86E-23 T 12-10-2018 MIM_c29580 3ed40dd3612402c869ac193cb026d27e 54 PIRSF PIRSF000071 1 54 1.8E-26 T 12-10-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 MIM_c29580 3ed40dd3612402c869ac193cb026d27e 54 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 12-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 MIM_c06150 a9a131ef0c83f27f07af4a2da0d9f191 381 Gene3D G3DSA:3.20.20.140 310 343 4.4E-8 T 12-10-2018 MIM_c06150 a9a131ef0c83f27f07af4a2da0d9f191 381 Gene3D G3DSA:2.30.40.10 7 53 1.2E-10 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MIM_c06150 a9a131ef0c83f27f07af4a2da0d9f191 381 Gene3D G3DSA:3.20.20.140 54 169 1.2E-10 T 12-10-2018 MIM_c06150 a9a131ef0c83f27f07af4a2da0d9f191 381 SUPERFAMILY SSF51338 4 366 6.05E-11 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MIM_c06150 a9a131ef0c83f27f07af4a2da0d9f191 381 Gene3D G3DSA:2.30.40.10 344 377 4.4E-8 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MIM_c06150 a9a131ef0c83f27f07af4a2da0d9f191 381 PIRSF PIRSF038971 3 381 2.2E-143 T 12-10-2018 IPR012696 Phosphonate metabolism PhnM GO:0019700 KEGG: 00440+3.6.1.63|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 MIM_c06150 a9a131ef0c83f27f07af4a2da0d9f191 381 TIGRFAM TIGR02318 phosphono_phnM: phosphonate metabolism protein PhnM 6 381 3.9E-149 T 12-10-2018 IPR012696 Phosphonate metabolism PhnM GO:0019700 KEGG: 00440+3.6.1.63|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 MIM_c06150 a9a131ef0c83f27f07af4a2da0d9f191 381 Pfam PF01979 Amidohydrolase family 283 380 3.5E-9 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MIM_c06150 a9a131ef0c83f27f07af4a2da0d9f191 381 SUPERFAMILY SSF51556 54 348 4.59E-16 T 12-10-2018 IPR032466 Metal-dependent hydrolase MIM_c08220 894a46d88445a8a14c2f4b22975ec4d7 119 Pfam PF12643 MazG-like family 35 117 7.3E-16 T 12-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 MIM_c08220 894a46d88445a8a14c2f4b22975ec4d7 119 PIRSF PIRSF029826 1 117 5.7E-42 T 12-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 MIM_c08220 894a46d88445a8a14c2f4b22975ec4d7 119 Gene3D G3DSA:1.10.287.1080 1 115 1.1E-32 T 12-10-2018 MIM_c08220 894a46d88445a8a14c2f4b22975ec4d7 119 SUPERFAMILY SSF101386 3 116 3.76E-36 T 12-10-2018 MIM_c24470 0f4802b396891f0a8653dd3b7a6a890f 496 Pfam PF01059 NADH-ubiquinone oxidoreductase chain 4, amino terminus 75 129 3.7E-5 T 12-10-2018 IPR000260 NADH:ubiquinone oxidoreductase chain 4, N-terminal GO:0006120|GO:0055114 KEGG: 00190+1.6.5.3|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-5083|MetaCyc: PWY-6692|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24470 0f4802b396891f0a8653dd3b7a6a890f 496 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 11 490 5.6E-184 T 12-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24470 0f4802b396891f0a8653dd3b7a6a890f 496 Pfam PF00361 Proton-conducting membrane transporter 138 420 2.6E-78 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24470 0f4802b396891f0a8653dd3b7a6a890f 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 241 265 3.2E-49 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24470 0f4802b396891f0a8653dd3b7a6a890f 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 381 407 3.2E-49 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24470 0f4802b396891f0a8653dd3b7a6a890f 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 172 196 3.2E-49 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24470 0f4802b396891f0a8653dd3b7a6a890f 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 142 161 3.2E-49 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24470 0f4802b396891f0a8653dd3b7a6a890f 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 329 348 3.2E-49 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c39740 aec6faa72d417333d09a8571e2b5b4c2 797 Pfam PF00171 Aldehyde dehydrogenase family 43 485 8.2E-156 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c39740 aec6faa72d417333d09a8571e2b5b4c2 797 Pfam PF00171 Aldehyde dehydrogenase family 544 760 2.8E-37 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c39740 aec6faa72d417333d09a8571e2b5b4c2 797 SUPERFAMILY SSF53720 24 486 2.23E-155 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c39740 aec6faa72d417333d09a8571e2b5b4c2 797 Gene3D G3DSA:3.40.605.10 37 485 7.3E-163 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c39740 aec6faa72d417333d09a8571e2b5b4c2 797 Gene3D G3DSA:3.40.605.10 519 795 6.6E-49 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c39740 aec6faa72d417333d09a8571e2b5b4c2 797 PIRSF PIRSF036490 1 797 0.0 T 12-10-2018 IPR011408 Aldehyde dehydrogenase MIM_c39740 aec6faa72d417333d09a8571e2b5b4c2 797 SUPERFAMILY SSF53720 513 762 3.4E-44 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c39740 aec6faa72d417333d09a8571e2b5b4c2 797 Gene3D G3DSA:3.40.309.10 269 459 7.3E-163 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MIM_c39740 aec6faa72d417333d09a8571e2b5b4c2 797 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 264 271 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MIM_c35110 3f167caaea3016ab9be1e391792199a4 130 Pfam PF13665 Domain of unknown function (DUF4150) 10 115 3.7E-29 T 12-10-2018 IPR025425 Domain of unknown function DUF4150 MIM_c27270 76e6e14aea63dade6b9a267923608425 409 Pfam PF13458 Periplasmic binding protein 31 366 3.5E-82 T 12-10-2018 IPR028081 Leucine-binding protein domain MIM_c27270 76e6e14aea63dade6b9a267923608425 409 Gene3D G3DSA:3.40.50.2300 31 332 2.1E-107 T 12-10-2018 MIM_c27270 76e6e14aea63dade6b9a267923608425 409 SUPERFAMILY SSF53822 31 399 1.04E-86 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c27270 76e6e14aea63dade6b9a267923608425 409 Gene3D G3DSA:3.40.50.2300 150 281 2.1E-107 T 12-10-2018 MIM_c14680 265fed6b666f71e889d76a61d485cec9 353 Gene3D G3DSA:1.10.8.60 152 222 3.8E-26 T 12-10-2018 MIM_c14680 265fed6b666f71e889d76a61d485cec9 353 Gene3D G3DSA:3.40.50.300 13 148 7.7E-38 T 12-10-2018 MIM_c14680 265fed6b666f71e889d76a61d485cec9 353 Gene3D G3DSA:1.20.272.10 223 352 5.3E-21 T 12-10-2018 MIM_c14680 265fed6b666f71e889d76a61d485cec9 353 SUPERFAMILY SSF48019 221 346 1.7E-21 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MIM_c14680 265fed6b666f71e889d76a61d485cec9 353 Pfam PF06144 DNA polymerase III, delta subunit 26 198 7.9E-20 T 12-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 MIM_c14680 265fed6b666f71e889d76a61d485cec9 353 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 22 346 2.0E-72 T 12-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 MIM_c14680 265fed6b666f71e889d76a61d485cec9 353 SUPERFAMILY SSF52540 20 219 4.25E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c08030 6b20517656c2b7c9e54e3b6cf4e7e82b 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 314 1.3E-37 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c08030 6b20517656c2b7c9e54e3b6cf4e7e82b 315 SUPERFAMILY SSF161098 90 297 8.5E-14 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c08030 6b20517656c2b7c9e54e3b6cf4e7e82b 315 Gene3D G3DSA:1.10.3720.10 85 310 6.6E-20 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c26320 5fe5c6fdd319027c11938d91ef76a00a 349 Gene3D G3DSA:3.30.1330.10 8 172 1.7E-67 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MIM_c26320 5fe5c6fdd319027c11938d91ef76a00a 349 SUPERFAMILY SSF55326 9 172 1.92E-52 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MIM_c26320 5fe5c6fdd319027c11938d91ef76a00a 349 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 9 338 2.0E-136 T 12-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MIM_c26320 5fe5c6fdd319027c11938d91ef76a00a 349 SUPERFAMILY SSF56042 173 344 7.18E-57 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MIM_c26320 5fe5c6fdd319027c11938d91ef76a00a 349 Pfam PF02769 AIR synthase related protein, C-terminal domain 179 341 2.8E-36 T 12-10-2018 IPR010918 PurM-like, C-terminal domain MIM_c26320 5fe5c6fdd319027c11938d91ef76a00a 349 Gene3D G3DSA:3.90.650.10 173 348 1.7E-66 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MIM_c26320 5fe5c6fdd319027c11938d91ef76a00a 349 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 9 348 45.972 T 12-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MIM_c26320 5fe5c6fdd319027c11938d91ef76a00a 349 Pfam PF00586 AIR synthase related protein, N-terminal domain 59 166 1.2E-14 T 12-10-2018 IPR016188 PurM-like, N-terminal domain MIM_c23990 91c1ec418932de50b2216784d7d93c6b 269 SUPERFAMILY SSF55846 30 184 1.44E-43 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MIM_c23990 91c1ec418932de50b2216784d7d93c6b 269 Gene3D G3DSA:1.10.101.10 183 262 2.1E-20 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 MIM_c23990 91c1ec418932de50b2216784d7d93c6b 269 SUPERFAMILY SSF47090 200 261 3.14E-17 T 12-10-2018 IPR036365 PGBD-like superfamily MIM_c23990 91c1ec418932de50b2216784d7d93c6b 269 Gene3D G3DSA:3.40.80.10 39 182 1.4E-45 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MIM_c23990 91c1ec418932de50b2216784d7d93c6b 269 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 39 169 8.2E-26 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MIM_c23990 91c1ec418932de50b2216784d7d93c6b 269 Pfam PF01471 Putative peptidoglycan binding domain 207 256 4.4E-8 T 12-10-2018 IPR002477 Peptidoglycan binding-like MIM_c23990 91c1ec418932de50b2216784d7d93c6b 269 SMART SM00644 29 168 8.7E-25 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MIM_c19460 2b1ccb075f306ec2e5a0e2ff4f3445ff 389 Pfam PF02684 Lipid-A-disaccharide synthetase 7 382 7.7E-91 T 12-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 MIM_c19460 2b1ccb075f306ec2e5a0e2ff4f3445ff 389 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 5 384 5.1E-91 T 12-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 MIM_c19460 2b1ccb075f306ec2e5a0e2ff4f3445ff 389 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 2 388 34.627 T 12-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 MIM_c19460 2b1ccb075f306ec2e5a0e2ff4f3445ff 389 SUPERFAMILY SSF53756 8 368 1.28E-29 T 12-10-2018 MIM_c20440 35dab4feea925b2657f1c1f48a9c6485 302 Gene3D G3DSA:1.10.1040.10 169 298 7.1E-34 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MIM_c20440 35dab4feea925b2657f1c1f48a9c6485 302 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 171 290 2.6E-30 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MIM_c20440 35dab4feea925b2657f1c1f48a9c6485 302 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 10 168 1.2E-43 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 MIM_c20440 35dab4feea925b2657f1c1f48a9c6485 302 SUPERFAMILY SSF51735 10 170 2.06E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c20440 35dab4feea925b2657f1c1f48a9c6485 302 SUPERFAMILY SSF48179 170 297 2.04E-31 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c20440 35dab4feea925b2657f1c1f48a9c6485 302 PIRSF PIRSF000103 3 298 6.2E-75 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 MIM_c20440 35dab4feea925b2657f1c1f48a9c6485 302 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 12 25 - T 12-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 MIM_c20440 35dab4feea925b2657f1c1f48a9c6485 302 Gene3D G3DSA:3.40.50.720 4 168 7.0E-49 T 12-10-2018 MIM_c33410 c29b37e9b87ebe41f143be7f41587c97 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 71 3.4E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c33410 c29b37e9b87ebe41f143be7f41587c97 207 SUPERFAMILY SSF46689 13 87 2.31E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c33410 c29b37e9b87ebe41f143be7f41587c97 207 SUPERFAMILY SSF48498 96 206 1.36E-15 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MIM_c33410 c29b37e9b87ebe41f143be7f41587c97 207 Gene3D G3DSA:1.10.10.60 11 79 5.1E-24 T 12-10-2018 MIM_c33410 c29b37e9b87ebe41f143be7f41587c97 207 Gene3D G3DSA:1.10.357.10 80 207 3.3E-18 T 12-10-2018 MIM_c33410 c29b37e9b87ebe41f143be7f41587c97 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 2.2E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c33410 c29b37e9b87ebe41f143be7f41587c97 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 2.2E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c33410 c29b37e9b87ebe41f143be7f41587c97 207 ProSitePatterns PS01081 TetR-type HTH domain signature. 38 68 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MIM_c16830 87a0ac2516ff0f4d8f3d8f0369494aa0 378 Gene3D G3DSA:1.10.540.10 20 123 6.5E-18 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c16830 87a0ac2516ff0f4d8f3d8f0369494aa0 378 PIRSF PIRSF016578 3 238 1.6E-13 T 12-10-2018 MIM_c16830 87a0ac2516ff0f4d8f3d8f0369494aa0 378 PIRSF PIRSF016578 282 357 0.26 T 12-10-2018 MIM_c16830 87a0ac2516ff0f4d8f3d8f0369494aa0 378 Gene3D G3DSA:2.40.110.10 133 232 1.4E-17 T 12-10-2018 MIM_c16830 87a0ac2516ff0f4d8f3d8f0369494aa0 378 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 121 3.1E-11 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c16830 87a0ac2516ff0f4d8f3d8f0369494aa0 378 SUPERFAMILY SSF47203 282 360 6.09E-6 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c16830 87a0ac2516ff0f4d8f3d8f0369494aa0 378 SUPERFAMILY SSF56645 9 227 4.45E-43 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c16830 87a0ac2516ff0f4d8f3d8f0369494aa0 378 Gene3D G3DSA:1.20.140.10 252 368 2.6E-5 T 12-10-2018 MIM_c20020 98952f495914253fcd1a58f8c54cf980 429 PIRSF PIRSF006066 1 429 2.9E-77 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 MIM_c20020 98952f495914253fcd1a58f8c54cf980 429 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 21 423 7.5E-91 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 MIM_c20020 98952f495914253fcd1a58f8c54cf980 429 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 418 1.3E-82 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit MIM_c20020 98952f495914253fcd1a58f8c54cf980 429 PRINTS PR00173 Glutamate-aspartate symporter signature 289 309 1.4E-5 T 12-10-2018 MIM_c20020 98952f495914253fcd1a58f8c54cf980 429 PRINTS PR00173 Glutamate-aspartate symporter signature 225 251 1.4E-5 T 12-10-2018 MIM_c20020 98952f495914253fcd1a58f8c54cf980 429 PRINTS PR00173 Glutamate-aspartate symporter signature 156 175 1.4E-5 T 12-10-2018 MIM_c20020 98952f495914253fcd1a58f8c54cf980 429 PRINTS PR00173 Glutamate-aspartate symporter signature 1 10 1.4E-5 T 12-10-2018 MIM_c30220 06fe77a5278a32fd408eae2d7176aabd 245 SUPERFAMILY SSF53639 14 235 6.47E-51 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily MIM_c30220 06fe77a5278a32fd408eae2d7176aabd 245 Gene3D G3DSA:3.40.225.10 11 245 9.5E-54 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily MIM_c30220 06fe77a5278a32fd408eae2d7176aabd 245 SMART SM01007 22 203 6.5E-36 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal MIM_c30220 06fe77a5278a32fd408eae2d7176aabd 245 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 23 202 3.4E-35 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal MIM_c02590 86242656e92e062d7529683aeb060b6a 171 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 11 153 8.5E-16 T 12-10-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like MIM_c02590 86242656e92e062d7529683aeb060b6a 171 Gene3D G3DSA:3.10.490.10 9 160 6.2E-20 T 12-10-2018 MIM_c02590 86242656e92e062d7529683aeb060b6a 171 SUPERFAMILY SSF110857 9 156 7.06E-18 T 12-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily MIM_c04000 2886fd176fb1f2d2e2078876f350fe7b 322 Gene3D G3DSA:3.60.130.10 21 321 1.9E-92 T 12-10-2018 MIM_c04000 2886fd176fb1f2d2e2078876f350fe7b 322 SUPERFAMILY SSF51197 22 301 1.01E-77 T 12-10-2018 MIM_c04000 2886fd176fb1f2d2e2078876f350fe7b 322 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 24 275 6.4E-55 T 12-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 MIM_c30490 a334e157eb99cec08c3ec01da3cf37a3 237 SUPERFAMILY SSF46785 22 94 2.66E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c30490 a334e157eb99cec08c3ec01da3cf37a3 237 Gene3D G3DSA:1.20.120.530 97 227 3.3E-16 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c30490 a334e157eb99cec08c3ec01da3cf37a3 237 SUPERFAMILY SSF48008 100 225 5.23E-15 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c30490 a334e157eb99cec08c3ec01da3cf37a3 237 SMART SM00895 100 224 6.2E-13 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c30490 a334e157eb99cec08c3ec01da3cf37a3 237 Gene3D G3DSA:1.10.10.10 24 92 1.3E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c30490 a334e157eb99cec08c3ec01da3cf37a3 237 SMART SM00345 32 90 2.0E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c30490 a334e157eb99cec08c3ec01da3cf37a3 237 Pfam PF07729 FCD domain 101 222 2.5E-16 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c30490 a334e157eb99cec08c3ec01da3cf37a3 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 32 90 1.9E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c04750 11f86ee0c6453d23747e743283800fc0 278 SUPERFAMILY SSF52540 11 243 4.24E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c04750 11f86ee0c6453d23747e743283800fc0 278 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c04750 11f86ee0c6453d23747e743283800fc0 278 Gene3D G3DSA:3.40.50.300 11 256 3.4E-65 T 12-10-2018 MIM_c04750 11f86ee0c6453d23747e743283800fc0 278 SMART SM00382 37 234 4.6E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c04750 11f86ee0c6453d23747e743283800fc0 278 Pfam PF00005 ABC transporter 28 177 3.5E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c02230 6215364774ffd93ce875499b17f9aeb7 831 Pfam PF00924 Mechanosensitive ion channel 544 743 1.5E-34 T 12-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MIM_c02230 6215364774ffd93ce875499b17f9aeb7 831 Gene3D G3DSA:2.30.30.60 603 651 1.7E-11 T 12-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily MIM_c02230 6215364774ffd93ce875499b17f9aeb7 831 Gene3D G3DSA:3.30.70.100 655 742 2.5E-20 T 12-10-2018 MIM_c02230 6215364774ffd93ce875499b17f9aeb7 831 SUPERFAMILY SSF82861 499 585 1.44E-13 T 12-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 MIM_c02230 6215364774ffd93ce875499b17f9aeb7 831 SUPERFAMILY SSF50182 587 647 1.01E-10 T 12-10-2018 IPR010920 LSM domain superfamily MIM_c02230 6215364774ffd93ce875499b17f9aeb7 831 SUPERFAMILY SSF82689 659 755 1.83E-13 T 12-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MIM_c06080 c0088da8c84fa17d8c93f0d9631c20f3 240 TIGRFAM TIGR02325 C_P_lyase_phnF: phosphonate metabolism transcriptional regulator PhnF 11 233 1.0E-51 T 12-10-2018 IPR012702 Phosphonate C-P lyase system, transcriptional regulator PhnF MIM_c06080 c0088da8c84fa17d8c93f0d9631c20f3 240 SUPERFAMILY SSF64288 60 236 1.88E-36 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MIM_c06080 c0088da8c84fa17d8c93f0d9631c20f3 240 SUPERFAMILY SSF46785 7 82 9.23E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c06080 c0088da8c84fa17d8c93f0d9631c20f3 240 Pfam PF07702 UTRA domain 94 230 1.6E-27 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MIM_c06080 c0088da8c84fa17d8c93f0d9631c20f3 240 Gene3D G3DSA:3.40.1410.10 81 238 2.3E-32 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MIM_c06080 c0088da8c84fa17d8c93f0d9631c20f3 240 SMART SM00345 11 72 1.5E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c06080 c0088da8c84fa17d8c93f0d9631c20f3 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 1.1E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c06080 c0088da8c84fa17d8c93f0d9631c20f3 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 1.1E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c06080 c0088da8c84fa17d8c93f0d9631c20f3 240 Gene3D G3DSA:1.10.10.10 10 76 2.3E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c06080 c0088da8c84fa17d8c93f0d9631c20f3 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 72 1.6E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c06080 c0088da8c84fa17d8c93f0d9631c20f3 240 SMART SM00866 93 230 1.3E-24 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MIM_c34170 b9ba8ecb2441a085ff1b52bfb9000e9f 494 Gene3D G3DSA:3.90.1300.10 1 493 2.1E-164 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MIM_c34170 b9ba8ecb2441a085ff1b52bfb9000e9f 494 SUPERFAMILY SSF75304 3 477 6.41E-116 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MIM_c34170 b9ba8ecb2441a085ff1b52bfb9000e9f 494 Pfam PF01425 Amidase 27 468 6.7E-90 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MIM_c34170 b9ba8ecb2441a085ff1b52bfb9000e9f 494 ProSitePatterns PS00571 Amidases signature. 157 188 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 MIM_c11200 d62a1073b53f0c5f06f6e7e85bcd79d4 455 SUPERFAMILY SSF103378 14 448 3.14E-118 T 12-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 MIM_c11200 d62a1073b53f0c5f06f6e7e85bcd79d4 455 Pfam PF03972 MmgE/PrpD family 17 441 2.4E-126 T 12-10-2018 IPR005656 MmgE/PrpD GO:0016829 MIM_c11200 d62a1073b53f0c5f06f6e7e85bcd79d4 455 Gene3D G3DSA:1.10.4100.10 38 419 2.1E-114 T 12-10-2018 MIM_c11200 d62a1073b53f0c5f06f6e7e85bcd79d4 455 Gene3D G3DSA:3.30.1330.120 278 403 2.1E-114 T 12-10-2018 MIM_c16960 9434c8e25a04a2eee02ae33677adbd43 429 Pfam PF13609 Gram-negative porin 10 398 6.5E-46 T 12-10-2018 MIM_c16960 9434c8e25a04a2eee02ae33677adbd43 429 SUPERFAMILY SSF56935 22 429 1.16E-64 T 12-10-2018 MIM_c16960 9434c8e25a04a2eee02ae33677adbd43 429 PRINTS PR00184 Neisseria sp. porin signature 71 96 5.6E-8 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 MIM_c16960 9434c8e25a04a2eee02ae33677adbd43 429 PRINTS PR00184 Neisseria sp. porin signature 172 189 5.6E-8 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 MIM_c05730 067e5be5a46c78b1043750b1ec881cfc 257 SUPERFAMILY SSF161098 56 241 4.71E-31 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c05730 067e5be5a46c78b1043750b1ec881cfc 257 Gene3D G3DSA:1.10.3720.10 57 253 1.1E-28 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c05730 067e5be5a46c78b1043750b1ec881cfc 257 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 240 6.3E-25 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c40760 782215030ab9db3d62379f01f4b00cc0 266 Gene3D G3DSA:3.40.50.300 2 266 7.8E-79 T 12-10-2018 MIM_c40760 782215030ab9db3d62379f01f4b00cc0 266 Pfam PF13614 AAA domain 9 184 1.8E-64 T 12-10-2018 IPR025669 AAA domain MIM_c40760 782215030ab9db3d62379f01f4b00cc0 266 PIRSF PIRSF009320 101 266 7.5E-8 T 12-10-2018 MIM_c40760 782215030ab9db3d62379f01f4b00cc0 266 PIRSF PIRSF009320 9 67 6.1E-14 T 12-10-2018 MIM_c40760 782215030ab9db3d62379f01f4b00cc0 266 SUPERFAMILY SSF52540 8 260 2.07E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c24830 483ec8efa4ea2ba46b7146d4a4397a3d 264 SUPERFAMILY SSF52096 3 254 1.01E-65 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c24830 483ec8efa4ea2ba46b7146d4a4397a3d 264 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 254 1.1E-48 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c24830 483ec8efa4ea2ba46b7146d4a4397a3d 264 Gene3D G3DSA:3.90.226.10 3 256 9.8E-63 T 12-10-2018 MIM_c09080 0a5e749c5db2abd42e424ef2dc1d1f87 380 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 328 352 - T 12-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c09080 0a5e749c5db2abd42e424ef2dc1d1f87 380 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 12 367 1.8E-123 T 12-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c09080 0a5e749c5db2abd42e424ef2dc1d1f87 380 Hamap MF_02079 Peptidoglycan glycosyltransferase MrdB [mrdB]. 6 373 26.94 T 12-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c09080 0a5e749c5db2abd42e424ef2dc1d1f87 380 Pfam PF01098 Cell cycle protein 18 369 2.6E-95 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c02500 16dcb976dc161aafc01f1ae0600a274f 324 Gene3D G3DSA:3.40.190.10 126 249 2.3E-112 T 12-10-2018 MIM_c02500 16dcb976dc161aafc01f1ae0600a274f 324 PIRSF PIRSF017082 1 324 2.0E-85 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c02500 16dcb976dc161aafc01f1ae0600a274f 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 319 1.3E-86 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c02500 16dcb976dc161aafc01f1ae0600a274f 324 SUPERFAMILY SSF53850 114 288 9.51E-17 T 12-10-2018 MIM_c02500 16dcb976dc161aafc01f1ae0600a274f 324 Gene3D G3DSA:3.40.190.150 29 314 2.3E-112 T 12-10-2018 MIM_c17320 c9c74ec3e4091ef206f0b90908789f03 154 SMART SM00344 3 112 1.2E-36 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MIM_c17320 c9c74ec3e4091ef206f0b90908789f03 154 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 50 5.4E-17 T 12-10-2018 MIM_c17320 c9c74ec3e4091ef206f0b90908789f03 154 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 12-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site MIM_c17320 c9c74ec3e4091ef206f0b90908789f03 154 SUPERFAMILY SSF54909 64 151 8.31E-16 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel MIM_c17320 c9c74ec3e4091ef206f0b90908789f03 154 Gene3D G3DSA:1.10.10.10 4 55 2.7E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c17320 c9c74ec3e4091ef206f0b90908789f03 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 2.3E-11 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MIM_c17320 c9c74ec3e4091ef206f0b90908789f03 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 2.3E-11 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MIM_c17320 c9c74ec3e4091ef206f0b90908789f03 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 2.3E-11 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MIM_c17320 c9c74ec3e4091ef206f0b90908789f03 154 SUPERFAMILY SSF46785 2 62 7.25E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c17320 c9c74ec3e4091ef206f0b90908789f03 154 Pfam PF01037 Lrp/AsnC ligand binding domain 69 141 1.6E-15 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MIM_c17320 c9c74ec3e4091ef206f0b90908789f03 154 Gene3D G3DSA:3.30.70.920 56 139 1.6E-19 T 12-10-2018 MIM_c17240 1f0ada90d31a95dbbabd8523adaf488a 401 SUPERFAMILY SSF103473 13 392 9.02E-62 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c17240 1f0ada90d31a95dbbabd8523adaf488a 401 Gene3D G3DSA:1.20.1250.20 13 396 7.9E-51 T 12-10-2018 MIM_c17240 1f0ada90d31a95dbbabd8523adaf488a 401 Pfam PF07690 Major Facilitator Superfamily 249 390 1.7E-19 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c17240 1f0ada90d31a95dbbabd8523adaf488a 401 Pfam PF07690 Major Facilitator Superfamily 20 231 7.7E-23 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c19810 6bcf757c3b452e8075ce2479348b305b 217 Gene3D G3DSA:1.10.3720.10 3 215 4.9E-55 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c19810 6bcf757c3b452e8075ce2479348b305b 217 SUPERFAMILY SSF161098 15 209 1.24E-45 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c19810 6bcf757c3b452e8075ce2479348b305b 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 213 2.7E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c19810 6bcf757c3b452e8075ce2479348b305b 217 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 109 1.3E-28 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c03370 2155535d63ad354033448bd9abbfbb9c 302 Gene3D G3DSA:3.20.20.140 8 299 6.9E-69 T 12-10-2018 MIM_c03370 2155535d63ad354033448bd9abbfbb9c 302 Pfam PF04909 Amidohydrolase 28 296 7.2E-21 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MIM_c03370 2155535d63ad354033448bd9abbfbb9c 302 SUPERFAMILY SSF51556 23 296 1.13E-57 T 12-10-2018 IPR032466 Metal-dependent hydrolase MIM_c30100 aad89b0dfa2940314b00a42cbffa57df 657 Pfam PF01032 FecCD transport family 9 319 1.2E-61 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MIM_c30100 aad89b0dfa2940314b00a42cbffa57df 657 Pfam PF01032 FecCD transport family 380 651 9.8E-58 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MIM_c30100 aad89b0dfa2940314b00a42cbffa57df 657 Gene3D G3DSA:1.10.3470.10 3 326 5.1E-65 T 12-10-2018 IPR037294 ABC transporter, BtuC-like MIM_c30100 aad89b0dfa2940314b00a42cbffa57df 657 Gene3D G3DSA:1.10.3470.10 340 656 1.1E-61 T 12-10-2018 IPR037294 ABC transporter, BtuC-like MIM_c30100 aad89b0dfa2940314b00a42cbffa57df 657 SUPERFAMILY SSF81345 347 653 4.84E-54 T 12-10-2018 IPR037294 ABC transporter, BtuC-like MIM_c30100 aad89b0dfa2940314b00a42cbffa57df 657 SUPERFAMILY SSF81345 9 319 6.8E-52 T 12-10-2018 IPR037294 ABC transporter, BtuC-like MIM_c35910 beebb3238b286181fd4476cfac91f64e 213 SUPERFAMILY SSF52016 2 186 8.24E-48 T 12-10-2018 MIM_c35910 beebb3238b286181fd4476cfac91f64e 213 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 6 183 1.7E-53 T 12-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 MIM_c35910 beebb3238b286181fd4476cfac91f64e 213 Pfam PF00694 Aconitase C-terminal domain 8 122 1.3E-27 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 MIM_c35910 beebb3238b286181fd4476cfac91f64e 213 Gene3D G3DSA:3.20.19.10 1 178 1.3E-59 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 MIM_c19450 13c1e40f713ec91278fc354a4067363e 264 Gene3D G3DSA:1.20.1180.10 194 263 2.2E-21 T 12-10-2018 IPR037157 UDP-N-acetylglucosamine O-acyltransferase, C-terminal domain superfamily KEGG: 00540+2.3.1.129 MIM_c19450 13c1e40f713ec91278fc354a4067363e 264 SUPERFAMILY SSF51161 4 245 5.35E-73 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily MIM_c19450 13c1e40f713ec91278fc354a4067363e 264 Gene3D G3DSA:2.160.10.10 1 191 4.1E-49 T 12-10-2018 MIM_c19450 13c1e40f713ec91278fc354a4067363e 264 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 2 263 42.997 T 12-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 MIM_c19450 13c1e40f713ec91278fc354a4067363e 264 PIRSF PIRSF000456 1 264 2.4E-98 T 12-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 MIM_c19450 13c1e40f713ec91278fc354a4067363e 264 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 5 261 1.2E-98 T 12-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 MIM_c19450 13c1e40f713ec91278fc354a4067363e 264 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 15 49 6.3E-7 T 12-10-2018 IPR001451 Hexapeptide repeat MIM_c19450 13c1e40f713ec91278fc354a4067363e 264 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 106 139 6.0E-8 T 12-10-2018 IPR001451 Hexapeptide repeat MIM_c19450 13c1e40f713ec91278fc354a4067363e 264 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 177 261 2.5E-24 T 12-10-2018 IPR029098 UDP N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00540+2.3.1.129 MIM_c10060 1bb2345327a5ea084f49f7e235c5781f 266 Pfam PF05690 Thiazole biosynthesis protein ThiG 6 257 3.5E-103 T 12-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 MIM_c10060 1bb2345327a5ea084f49f7e235c5781f 266 Gene3D G3DSA:3.20.20.70 1 263 8.3E-103 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c10060 1bb2345327a5ea084f49f7e235c5781f 266 Hamap MF_00443 Thiazole synthase [thiG]. 3 264 41.711 T 12-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 MIM_c10060 1bb2345327a5ea084f49f7e235c5781f 266 SUPERFAMILY SSF110399 3 249 1.57E-80 T 12-10-2018 MIM_c15460 b07f7922e73538d813bac28a4d329190 539 Gene3D G3DSA:3.30.560.10 49 474 1.1E-169 T 12-10-2018 MIM_c15460 b07f7922e73538d813bac28a4d329190 539 Pfam PF05199 GMC oxidoreductase 393 529 2.5E-35 T 12-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 MIM_c15460 b07f7922e73538d813bac28a4d329190 539 SUPERFAMILY SSF54373 296 479 8.54E-53 T 12-10-2018 MIM_c15460 b07f7922e73538d813bac28a4d329190 539 Pfam PF00732 GMC oxidoreductase 11 301 4.3E-80 T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c15460 b07f7922e73538d813bac28a4d329190 539 PIRSF PIRSF000137 1 539 3.3E-141 T 12-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c15460 b07f7922e73538d813bac28a4d329190 539 Gene3D G3DSA:3.50.50.60 11 533 1.1E-169 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c15460 b07f7922e73538d813bac28a4d329190 539 SUPERFAMILY SSF51905 10 536 3.15E-84 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c15460 b07f7922e73538d813bac28a4d329190 539 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 88 111 - T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c16440 4228d898a9792dc10bf86c19764af844 369 Gene3D G3DSA:3.20.20.300 21 367 1.2E-116 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 MIM_c16440 4228d898a9792dc10bf86c19764af844 369 Hamap MF_00364 Beta-hexosaminidase [nagZ]. 31 368 51.694 T 12-10-2018 IPR022956 Beta-hexosaminidase, bacterial GO:0004563 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 MIM_c16440 4228d898a9792dc10bf86c19764af844 369 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 265 282 - T 12-10-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 MIM_c16440 4228d898a9792dc10bf86c19764af844 369 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 34 322 8.6E-72 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MIM_c16440 4228d898a9792dc10bf86c19764af844 369 SUPERFAMILY SSF51445 30 339 1.05E-81 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily MIM_c16010 1b1e0aa9920cdc32e5bb9ed1dba8e355 225 Gene3D G3DSA:3.40.50.170 5 217 4.5E-70 T 12-10-2018 MIM_c16010 1b1e0aa9920cdc32e5bb9ed1dba8e355 225 SUPERFAMILY SSF53328 10 206 9.29E-57 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MIM_c16010 1b1e0aa9920cdc32e5bb9ed1dba8e355 225 Pfam PF00551 Formyl transferase 10 189 1.4E-51 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MIM_c16010 1b1e0aa9920cdc32e5bb9ed1dba8e355 225 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 10 196 29.439 T 12-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 MIM_c16010 1b1e0aa9920cdc32e5bb9ed1dba8e355 225 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 10 198 2.7E-63 T 12-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 MIM_c02250 408eebd2f1122280352f43d76fd9d5e7 146 Gene3D G3DSA:3.10.180.10 10 145 4.1E-48 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c02250 408eebd2f1122280352f43d76fd9d5e7 146 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 135 8.8E-13 T 12-10-2018 IPR028973 PhnB-like MIM_c02250 408eebd2f1122280352f43d76fd9d5e7 146 SUPERFAMILY SSF54593 5 140 6.72E-36 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c13630 0790d3cb71fd18ba54f78ab1b489a0b8 508 SUPERFAMILY SSF103473 7 419 2.09E-62 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c13630 0790d3cb71fd18ba54f78ab1b489a0b8 508 Gene3D G3DSA:1.20.1720.10 14 247 2.4E-38 T 12-10-2018 MIM_c13630 0790d3cb71fd18ba54f78ab1b489a0b8 508 Pfam PF07690 Major Facilitator Superfamily 20 409 1.8E-49 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c13630 0790d3cb71fd18ba54f78ab1b489a0b8 508 Gene3D G3DSA:1.20.1250.20 260 432 2.0E-16 T 12-10-2018 MIM_c13630 0790d3cb71fd18ba54f78ab1b489a0b8 508 PRINTS PR01036 Tetracycline resistance protein TetB signature 400 419 9.9E-6 T 12-10-2018 MIM_c13630 0790d3cb71fd18ba54f78ab1b489a0b8 508 PRINTS PR01036 Tetracycline resistance protein TetB signature 234 252 9.9E-6 T 12-10-2018 MIM_c13630 0790d3cb71fd18ba54f78ab1b489a0b8 508 PRINTS PR01036 Tetracycline resistance protein TetB signature 77 99 9.9E-6 T 12-10-2018 MIM_c13630 0790d3cb71fd18ba54f78ab1b489a0b8 508 PRINTS PR01036 Tetracycline resistance protein TetB signature 268 293 9.9E-6 T 12-10-2018 MIM_c10620 83e51796572f0223c556720e31c50cb2 147 Gene3D G3DSA:1.10.260.40 12 87 1.7E-12 T 12-10-2018 MIM_c10620 83e51796572f0223c556720e31c50cb2 147 Pfam PF01381 Helix-turn-helix 30 78 9.8E-11 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c10620 83e51796572f0223c556720e31c50cb2 147 SMART SM00530 29 84 5.0E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c10620 83e51796572f0223c556720e31c50cb2 147 SUPERFAMILY SSF47413 19 79 1.5E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c05530 9230d754a3e375e871be3c1ecc095577 152 Gene3D G3DSA:3.40.930.10 1 150 7.1E-52 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 MIM_c05530 9230d754a3e375e871be3c1ecc095577 152 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7 148 9.1E-34 T 12-10-2018 IPR002178 PTS EIIA type-2 domain MIM_c05530 9230d754a3e375e871be3c1ecc095577 152 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 12-10-2018 IPR002178 PTS EIIA type-2 domain MIM_c05530 9230d754a3e375e871be3c1ecc095577 152 SUPERFAMILY SSF55804 1 147 2.49E-39 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 MIM_c40780 40ac85484c9c67ab24442217eb34ee05 646 Gene3D G3DSA:1.10.10.1800 460 557 2.2E-26 T 12-10-2018 MIM_c40780 40ac85484c9c67ab24442217eb34ee05 646 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 274 288 - T 12-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 MIM_c40780 40ac85484c9c67ab24442217eb34ee05 646 Pfam PF01134 Glucose inhibited division protein A 8 398 3.1E-165 T 12-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 MIM_c40780 40ac85484c9c67ab24442217eb34ee05 646 Gene3D G3DSA:1.10.150.570 576 630 2.8E-25 T 12-10-2018 MIM_c40780 40ac85484c9c67ab24442217eb34ee05 646 SMART SM01228 553 624 8.2E-43 T 12-10-2018 MIM_c40780 40ac85484c9c67ab24442217eb34ee05 646 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 369 392 - T 12-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 MIM_c40780 40ac85484c9c67ab24442217eb34ee05 646 Gene3D G3DSA:3.50.50.60 296 459 2.9E-55 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c40780 40ac85484c9c67ab24442217eb34ee05 646 Gene3D G3DSA:3.50.50.60 2 223 3.4E-86 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c40780 40ac85484c9c67ab24442217eb34ee05 646 SUPERFAMILY SSF51905 6 262 2.95E-49 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c40780 40ac85484c9c67ab24442217eb34ee05 646 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 5 631 42.705 T 12-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 MIM_c40780 40ac85484c9c67ab24442217eb34ee05 646 Pfam PF13932 GidA associated domain 403 623 5.4E-78 T 12-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 MIM_c40780 40ac85484c9c67ab24442217eb34ee05 646 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 7 628 1.3E-272 T 12-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 MIM_c07090 13939a750870ed8fa390418ba219494d 170 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 161 2.6E-56 T 12-10-2018 IPR023635 Peptide deformylase MIM_c07090 13939a750870ed8fa390418ba219494d 170 Pfam PF01327 Polypeptide deformylase 5 153 2.8E-49 T 12-10-2018 IPR023635 Peptide deformylase MIM_c07090 13939a750870ed8fa390418ba219494d 170 SUPERFAMILY SSF56420 2 165 1.7E-61 T 12-10-2018 IPR036821 Peptide deformylase superfamily MIM_c07090 13939a750870ed8fa390418ba219494d 170 Hamap MF_00163 Peptide deformylase [def]. 2 163 30.757 T 12-10-2018 IPR023635 Peptide deformylase MIM_c07090 13939a750870ed8fa390418ba219494d 170 PIRSF PIRSF004749 1 170 5.6E-55 T 12-10-2018 IPR023635 Peptide deformylase MIM_c07090 13939a750870ed8fa390418ba219494d 170 PRINTS PR01576 Peptide deformylase signature 102 120 1.3E-35 T 12-10-2018 IPR023635 Peptide deformylase MIM_c07090 13939a750870ed8fa390418ba219494d 170 PRINTS PR01576 Peptide deformylase signature 90 101 1.3E-35 T 12-10-2018 IPR023635 Peptide deformylase MIM_c07090 13939a750870ed8fa390418ba219494d 170 PRINTS PR01576 Peptide deformylase signature 121 150 1.3E-35 T 12-10-2018 IPR023635 Peptide deformylase MIM_c07090 13939a750870ed8fa390418ba219494d 170 PRINTS PR01576 Peptide deformylase signature 33 62 1.3E-35 T 12-10-2018 IPR023635 Peptide deformylase MIM_c07090 13939a750870ed8fa390418ba219494d 170 Gene3D G3DSA:3.90.45.10 1 167 1.4E-64 T 12-10-2018 IPR036821 Peptide deformylase superfamily MIM_c10280 2163518ae7f5b5617e96368481c16a73 152 Gene3D G3DSA:3.10.450.50 9 142 3.2E-35 T 12-10-2018 MIM_c10280 2163518ae7f5b5617e96368481c16a73 152 SUPERFAMILY SSF54427 13 135 3.24E-29 T 12-10-2018 IPR032710 NTF2-like domain superfamily MIM_c10280 2163518ae7f5b5617e96368481c16a73 152 Pfam PF13474 SnoaL-like domain 20 132 5.6E-15 T 12-10-2018 IPR037401 SnoaL-like domain MIM_c38260 55197325b693f3c4908c5f34119aa502 203 Gene3D G3DSA:2.40.500.20 90 203 2.7E-45 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c38260 55197325b693f3c4908c5f34119aa502 203 SUPERFAMILY SSF46609 1 90 2.88E-35 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c38260 55197325b693f3c4908c5f34119aa502 203 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 164 171 - T 12-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c38260 55197325b693f3c4908c5f34119aa502 203 SUPERFAMILY SSF54719 88 201 7.33E-44 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c38260 55197325b693f3c4908c5f34119aa502 203 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 8.9E-28 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c38260 55197325b693f3c4908c5f34119aa502 203 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 8.9E-28 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c38260 55197325b693f3c4908c5f34119aa502 203 PRINTS PR01703 Manganese superoxide dismutase signature 72 85 8.9E-28 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c38260 55197325b693f3c4908c5f34119aa502 203 PRINTS PR01703 Manganese superoxide dismutase signature 162 174 8.9E-28 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c38260 55197325b693f3c4908c5f34119aa502 203 PRINTS PR01703 Manganese superoxide dismutase signature 125 133 8.9E-28 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c38260 55197325b693f3c4908c5f34119aa502 203 PIRSF PIRSF000349 1 203 6.1E-80 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c38260 55197325b693f3c4908c5f34119aa502 203 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 2 89 1.4E-32 T 12-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c38260 55197325b693f3c4908c5f34119aa502 203 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 96 197 9.7E-39 T 12-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c38260 55197325b693f3c4908c5f34119aa502 203 Gene3D G3DSA:1.10.287.990 20 89 6.3E-30 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c12080 31b168283caf7e7876108559472f4496 226 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 221 2.6E-112 T 12-10-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 MIM_c12080 31b168283caf7e7876108559472f4496 226 Pfam PF01144 Coenzyme A transferase 8 218 1.1E-66 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MIM_c12080 31b168283caf7e7876108559472f4496 226 SUPERFAMILY SSF100950 2 222 9.77E-79 T 12-10-2018 IPR037171 NagB/RpiA transferase-like MIM_c12080 31b168283caf7e7876108559472f4496 226 Gene3D G3DSA:3.40.1080.10 1 224 1.2E-82 T 12-10-2018 MIM_c12080 31b168283caf7e7876108559472f4496 226 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 12-10-2018 IPR004163 Coenzyme A transferase binding site GO:0008410 Reactome: R-HSA-77108 MIM_c12080 31b168283caf7e7876108559472f4496 226 SMART SM00882 6 219 3.3E-74 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MIM_c17450 8b649c7b23d461c5a7e2bff43bf54125 219 Pfam PF07302 AroM protein 105 211 8.0E-6 T 12-10-2018 IPR010843 Uncharacterised protein family AroM MIM_c17450 8b649c7b23d461c5a7e2bff43bf54125 219 SUPERFAMILY SSF53681 144 210 6.54E-6 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MIM_c17450 8b649c7b23d461c5a7e2bff43bf54125 219 Gene3D G3DSA:3.40.50.12500 4 219 1.6E-49 T 12-10-2018 MIM_c37240 1ed52deddcabcae13e64c6a1eb51cfdd 322 SUPERFAMILY SSF53850 115 287 1.2E-16 T 12-10-2018 MIM_c37240 1ed52deddcabcae13e64c6a1eb51cfdd 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 321 1.2E-58 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c37240 1ed52deddcabcae13e64c6a1eb51cfdd 322 Gene3D G3DSA:3.40.190.150 32 314 9.9E-94 T 12-10-2018 MIM_c37240 1ed52deddcabcae13e64c6a1eb51cfdd 322 Gene3D G3DSA:3.40.190.10 127 249 9.9E-94 T 12-10-2018 MIM_c37240 1ed52deddcabcae13e64c6a1eb51cfdd 322 PIRSF PIRSF017082 1 322 1.3E-110 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c17860 b1331377032546a6981c05693c37ea17 392 Gene3D G3DSA:3.20.20.70 69 356 3.2E-105 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c17860 b1331377032546a6981c05693c37ea17 392 Pfam PF04055 Radical SAM superfamily 111 301 5.1E-16 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MIM_c17860 b1331377032546a6981c05693c37ea17 392 SUPERFAMILY SSF102114 107 329 7.85E-11 T 12-10-2018 MIM_c17860 b1331377032546a6981c05693c37ea17 392 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 7 371 71.41 T 12-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 MIM_c17860 b1331377032546a6981c05693c37ea17 392 PIRSF PIRSF006004 4 384 2.3E-145 T 12-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 MIM_c17860 b1331377032546a6981c05693c37ea17 392 Gene3D G3DSA:1.10.150.530 1 68 7.3E-19 T 12-10-2018 MIM_c17860 b1331377032546a6981c05693c37ea17 392 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 3 374 6.8E-130 T 12-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 MIM_c05260 6811d925f67a639c411ff45a0ec1da57 247 TIGRFAM TIGR02444 TIGR02444: TIGR02444 family protein 13 125 1.1E-29 T 12-10-2018 IPR012659 Conserved hypothetical protein CHP02444 MIM_c05260 6811d925f67a639c411ff45a0ec1da57 247 Pfam PF09523 Protein of unknown function (DUF2390) 14 123 3.3E-32 T 12-10-2018 IPR012659 Conserved hypothetical protein CHP02444 MIM_c13200 abe0dbce93c85bcd807ec7a56151c074 378 Gene3D G3DSA:1.10.230.10 256 315 2.0E-95 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain MIM_c13200 abe0dbce93c85bcd807ec7a56151c074 378 PRINTS PR00143 Citrate synthase signature 158 171 3.0E-22 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 MIM_c13200 abe0dbce93c85bcd807ec7a56151c074 378 PRINTS PR00143 Citrate synthase signature 230 258 3.0E-22 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 MIM_c13200 abe0dbce93c85bcd807ec7a56151c074 378 PRINTS PR00143 Citrate synthase signature 283 303 3.0E-22 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 MIM_c13200 abe0dbce93c85bcd807ec7a56151c074 378 PRINTS PR00143 Citrate synthase signature 208 223 3.0E-22 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 MIM_c13200 abe0dbce93c85bcd807ec7a56151c074 378 ProSitePatterns PS00480 Citrate synthase signature. 290 302 - T 12-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MIM_c13200 abe0dbce93c85bcd807ec7a56151c074 378 SUPERFAMILY SSF48256 41 324 2.36E-88 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 MIM_c13200 abe0dbce93c85bcd807ec7a56151c074 378 Gene3D G3DSA:1.10.580.10 61 255 2.0E-95 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MIM_c13200 abe0dbce93c85bcd807ec7a56151c074 378 Pfam PF00285 Citrate synthase, C-terminal domain 41 316 3.1E-82 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 MIM_c10590 a75e0c55e6d1ff03c9e012abee4c10c2 146 SUPERFAMILY SSF55729 1 143 9.57E-23 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c10590 a75e0c55e6d1ff03c9e012abee4c10c2 146 Pfam PF13673 Acetyltransferase (GNAT) domain 53 135 2.1E-13 T 12-10-2018 IPR000182 GNAT domain MIM_c10590 a75e0c55e6d1ff03c9e012abee4c10c2 146 Gene3D G3DSA:3.40.630.30 1 145 1.6E-31 T 12-10-2018 MIM_c00050 5adfa134891077aa301b48ea854f0d09 308 SUPERFAMILY SSF46689 239 288 6.87E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c00050 5adfa134891077aa301b48ea854f0d09 308 SUPERFAMILY SSF46689 189 235 3.21E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c00050 5adfa134891077aa301b48ea854f0d09 308 SMART SM00342 202 285 5.3E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c00050 5adfa134891077aa301b48ea854f0d09 308 Gene3D G3DSA:1.10.10.60 182 298 6.0E-26 T 12-10-2018 MIM_c00050 5adfa134891077aa301b48ea854f0d09 308 Pfam PF12833 Helix-turn-helix domain 208 285 8.3E-16 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c10520 d628dbe17e5e4664a072d79833c1889d 134 Pfam PF00436 Single-strand binding protein family 4 100 1.1E-21 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 MIM_c10520 d628dbe17e5e4664a072d79833c1889d 134 Gene3D G3DSA:2.40.50.140 2 130 4.0E-31 T 12-10-2018 MIM_c10520 d628dbe17e5e4664a072d79833c1889d 134 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 4 117 5.2E-23 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 MIM_c10520 d628dbe17e5e4664a072d79833c1889d 134 PIRSF PIRSF002070 1 134 1.5E-26 T 12-10-2018 MIM_c10520 d628dbe17e5e4664a072d79833c1889d 134 Hamap MF_00984 Single-stranded DNA-binding protein. 3 105 23.253 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 MIM_c10520 d628dbe17e5e4664a072d79833c1889d 134 SUPERFAMILY SSF50249 3 134 4.86E-32 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c24380 c9589eb29e706d654804f896b625c330 161 SUPERFAMILY SSF69765 5 160 2.62E-63 T 12-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MIM_c24380 c9589eb29e706d654804f896b625c330 161 Pfam PF02542 YgbB family 6 158 8.5E-63 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MIM_c24380 c9589eb29e706d654804f896b625c330 161 Gene3D G3DSA:3.30.1330.50 4 161 2.3E-66 T 12-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MIM_c24380 c9589eb29e706d654804f896b625c330 161 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 39 54 - T 12-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MIM_c24380 c9589eb29e706d654804f896b625c330 161 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 6 159 2.4E-64 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MIM_c24380 c9589eb29e706d654804f896b625c330 161 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 5 160 35.01 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MIM_c27240 ae2b91eb160924a814786e88ce192903 329 Pfam PF02653 Branched-chain amino acid transport system / permease component 35 301 6.9E-39 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c36690 b3df4738d7fc6af89b25da45e682f469 421 Pfam PF09242 Flavocytochrome c sulphide dehydrogenase, flavin-binding 356 420 1.0E-19 T 12-10-2018 IPR015323 Flavocytochrome c sulphide dehydrogenase, flavin-binding GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 MIM_c36690 b3df4738d7fc6af89b25da45e682f469 421 Gene3D G3DSA:3.50.50.60 148 280 1.6E-96 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c36690 b3df4738d7fc6af89b25da45e682f469 421 SUPERFAMILY SSF51905 151 280 1.2E-36 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c36690 b3df4738d7fc6af89b25da45e682f469 421 Gene3D G3DSA:3.90.760.10 354 420 7.6E-9 T 12-10-2018 IPR037092 Flavocytochrome c sulphide dehydrogenase, flavin-binding domain superfamily GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 MIM_c36690 b3df4738d7fc6af89b25da45e682f469 421 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 34 141 3.5E-12 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MIM_c36690 b3df4738d7fc6af89b25da45e682f469 421 SUPERFAMILY SSF55424 355 420 8.24E-16 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MIM_c36690 b3df4738d7fc6af89b25da45e682f469 421 SUPERFAMILY SSF51905 33 148 3.24E-22 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c36690 b3df4738d7fc6af89b25da45e682f469 421 Gene3D G3DSA:3.50.50.60 34 342 1.6E-96 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c31360 ce8147d83f07f3c21289ec478e1ecfe7 485 Gene3D G3DSA:1.10.260.40 4 73 8.4E-15 T 12-10-2018 MIM_c31360 ce8147d83f07f3c21289ec478e1ecfe7 485 Pfam PF09856 Predicted transcriptional regulator (DUF2083) 325 481 1.8E-71 T 12-10-2018 IPR018653 Domain of unknown function DUF2083,transcriptional regulator MIM_c31360 ce8147d83f07f3c21289ec478e1ecfe7 485 Pfam PF06114 IrrE N-terminal-like domain 211 324 4.8E-17 T 12-10-2018 IPR010359 IrrE N-terminal-like domain MIM_c31360 ce8147d83f07f3c21289ec478e1ecfe7 485 PIRSF PIRSF019251 1 485 2.1E-189 T 12-10-2018 IPR026281 HTH-type transcriptional regulator RamB GO:0006355 MIM_c31360 ce8147d83f07f3c21289ec478e1ecfe7 485 Pfam PF01381 Helix-turn-helix 10 60 9.2E-12 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c31360 ce8147d83f07f3c21289ec478e1ecfe7 485 SUPERFAMILY SSF47413 3 68 4.83E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c31360 ce8147d83f07f3c21289ec478e1ecfe7 485 SMART SM00530 9 64 2.6E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c02000 15ea2ef4e366acacce54dbb77c9ceda3 331 Pfam PF02653 Branched-chain amino acid transport system / permease component 27 293 4.3E-42 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c26550 ca49c8d6a9ba9bc0726c0c6b3e1c5d3f 145 Gene3D G3DSA:3.30.530.20 1 143 3.0E-34 T 12-10-2018 IPR023393 START-like domain superfamily MIM_c26550 ca49c8d6a9ba9bc0726c0c6b3e1c5d3f 145 SUPERFAMILY SSF55961 7 140 6.92E-25 T 12-10-2018 MIM_c26550 ca49c8d6a9ba9bc0726c0c6b3e1c5d3f 145 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 7 100 3.3E-6 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase MIM_c03830 d4e0a3fa3c4a07357b5ab5fa29760fab 203 Pfam PF13302 Acetyltransferase (GNAT) domain 19 158 1.4E-15 T 12-10-2018 IPR000182 GNAT domain MIM_c03830 d4e0a3fa3c4a07357b5ab5fa29760fab 203 SUPERFAMILY SSF55729 10 183 2.24E-34 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c03830 d4e0a3fa3c4a07357b5ab5fa29760fab 203 Gene3D G3DSA:3.40.630.30 6 200 6.7E-45 T 12-10-2018 MIM_c05520 841ca982bed70b667b227c861773a93b 310 Pfam PF07475 HPr Serine kinase C-terminal domain 132 300 5.9E-64 T 12-10-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 MIM_c05520 841ca982bed70b667b227c861773a93b 310 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 4 303 1.8E-101 T 12-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 MIM_c05520 841ca982bed70b667b227c861773a93b 310 SUPERFAMILY SSF75138 10 133 1.01E-27 T 12-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily MIM_c05520 841ca982bed70b667b227c861773a93b 310 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 1 307 37.364 T 12-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 MIM_c05520 841ca982bed70b667b227c861773a93b 310 Gene3D G3DSA:3.40.50.300 133 310 3.8E-65 T 12-10-2018 MIM_c05520 841ca982bed70b667b227c861773a93b 310 Gene3D G3DSA:3.40.1390.20 2 132 5.2E-27 T 12-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily MIM_c05520 841ca982bed70b667b227c861773a93b 310 Pfam PF02603 HPr Serine kinase N terminus 3 129 3.4E-25 T 12-10-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 MIM_c05520 841ca982bed70b667b227c861773a93b 310 SUPERFAMILY SSF53795 134 299 8.55E-35 T 12-10-2018 MIM_c14990 c709441adb3d323763934eaf0b34467d 293 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 122 137 - T 12-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MIM_c14990 c709441adb3d323763934eaf0b34467d 293 TIGRFAM TIGR03465 HpnD: squalene synthase HpnD 10 275 3.0E-119 T 12-10-2018 IPR017828 Squalene synthase HpnD-like GO:0016117|GO:0016767 MIM_c14990 c709441adb3d323763934eaf0b34467d 293 Gene3D G3DSA:1.10.600.10 4 275 1.7E-86 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily MIM_c14990 c709441adb3d323763934eaf0b34467d 293 Pfam PF00494 Squalene/phytoene synthase 13 264 6.1E-81 T 12-10-2018 MIM_c14990 c709441adb3d323763934eaf0b34467d 293 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 152 177 - T 12-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MIM_c14990 c709441adb3d323763934eaf0b34467d 293 SUPERFAMILY SSF48576 4 276 2.3E-90 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily MIM_c09110 898c54f34bcb0dfb9db1e8b93361acc8 222 Pfam PF00005 ABC transporter 18 166 1.2E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c09110 898c54f34bcb0dfb9db1e8b93361acc8 222 SMART SM00382 27 214 8.5E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c09110 898c54f34bcb0dfb9db1e8b93361acc8 222 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c09110 898c54f34bcb0dfb9db1e8b93361acc8 222 SUPERFAMILY SSF52540 1 220 2.45E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c09110 898c54f34bcb0dfb9db1e8b93361acc8 222 Gene3D G3DSA:3.40.50.300 1 222 3.8E-64 T 12-10-2018 MIM_c34010 3a637b49547fd74c1f08621624c010b7 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 7.0E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c34010 3a637b49547fd74c1f08621624c010b7 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 7.0E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c34010 3a637b49547fd74c1f08621624c010b7 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 7.0E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c34010 3a637b49547fd74c1f08621624c010b7 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 7.0E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c34010 3a637b49547fd74c1f08621624c010b7 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 7.0E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c34010 3a637b49547fd74c1f08621624c010b7 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 7.0E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c34010 3a637b49547fd74c1f08621624c010b7 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 241 1.3E-57 T 12-10-2018 MIM_c34010 3a637b49547fd74c1f08621624c010b7 244 SUPERFAMILY SSF51735 5 241 3.19E-77 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c34010 3a637b49547fd74c1f08621624c010b7 244 Gene3D G3DSA:3.40.50.720 1 243 1.8E-76 T 12-10-2018 MIM_c34010 3a637b49547fd74c1f08621624c010b7 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 186 0.0014 T 12-10-2018 MIM_c15610 4b129b35aeac2ff643449895fcb15c14 416 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 410 2.7E-100 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MIM_c15610 4b129b35aeac2ff643449895fcb15c14 416 SUPERFAMILY SSF53383 8 411 4.49E-86 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c15610 4b129b35aeac2ff643449895fcb15c14 416 Gene3D G3DSA:3.40.640.10 7 276 9.2E-67 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c15610 4b129b35aeac2ff643449895fcb15c14 416 Gene3D G3DSA:3.90.1150.10 277 412 4.8E-39 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c15610 4b129b35aeac2ff643449895fcb15c14 416 PIRSF PIRSF001434 1 414 1.5E-113 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MIM_c20740 a0f61f55dc442f650748d74aa7066e3e 409 Gene3D G3DSA:3.40.50.2300 39 347 3.0E-90 T 12-10-2018 MIM_c20740 a0f61f55dc442f650748d74aa7066e3e 409 Pfam PF13458 Periplasmic binding protein 36 372 1.3E-68 T 12-10-2018 IPR028081 Leucine-binding protein domain MIM_c20740 a0f61f55dc442f650748d74aa7066e3e 409 SUPERFAMILY SSF53822 36 407 1.15E-71 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c20740 a0f61f55dc442f650748d74aa7066e3e 409 Gene3D G3DSA:3.40.50.2300 154 285 3.0E-90 T 12-10-2018 MIM_c07810 f0c57a36e23865beaca662500159460b 177 Pfam PF04002 RadC-like JAB domain 57 174 1.2E-36 T 12-10-2018 IPR025657 RadC-like JAB domain MIM_c07810 f0c57a36e23865beaca662500159460b 177 Gene3D G3DSA:3.40.140.10 54 177 2.0E-35 T 12-10-2018 MIM_c07810 f0c57a36e23865beaca662500159460b 177 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 126 131 - T 12-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site MIM_c41040 081c7235cb220bbf16c9916cd3ade159 241 Pfam PF09209 Domain of unknown function (DUF1956) 108 225 1.5E-24 T 12-10-2018 IPR015292 Transcription regulator YbiH, C-terminal MIM_c41040 081c7235cb220bbf16c9916cd3ade159 241 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 59 82 1.5E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c41040 081c7235cb220bbf16c9916cd3ade159 241 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 51 1.5E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c41040 081c7235cb220bbf16c9916cd3ade159 241 SUPERFAMILY SSF48498 106 228 3.38E-24 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MIM_c41040 081c7235cb220bbf16c9916cd3ade159 241 Gene3D G3DSA:1.10.357.10 25 238 7.2E-28 T 12-10-2018 MIM_c41040 081c7235cb220bbf16c9916cd3ade159 241 Pfam PF00440 Bacterial regulatory proteins, tetR family 38 82 3.1E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c41040 081c7235cb220bbf16c9916cd3ade159 241 SUPERFAMILY SSF46689 27 94 6.16E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c31010 51f89bc04419f283b5626b9f34b3541e 325 SUPERFAMILY SSF53850 51 281 2.53E-13 T 12-10-2018 MIM_c31010 51f89bc04419f283b5626b9f34b3541e 325 Gene3D G3DSA:3.40.190.10 125 249 9.1E-101 T 12-10-2018 MIM_c31010 51f89bc04419f283b5626b9f34b3541e 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 320 1.5E-80 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c31010 51f89bc04419f283b5626b9f34b3541e 325 Gene3D G3DSA:3.40.190.150 27 314 9.1E-101 T 12-10-2018 MIM_c31010 51f89bc04419f283b5626b9f34b3541e 325 PIRSF PIRSF017082 1 323 2.2E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c06230 33be55b9ce88edfaadec7eecf551e8b1 259 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 53 255 4.6E-11 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 MIM_c06230 33be55b9ce88edfaadec7eecf551e8b1 259 SUPERFAMILY SSF56529 5 256 6.98E-46 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MIM_c06230 33be55b9ce88edfaadec7eecf551e8b1 259 Gene3D G3DSA:3.90.850.10 3 257 8.1E-57 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MIM_c03820 8bd72bb8d71f3c65869798a4c9163e2c 303 Pfam PF03956 Lysine exporter LysO 114 298 1.4E-48 T 12-10-2018 IPR005642 Lysine exporter LysO MIM_c03820 8bd72bb8d71f3c65869798a4c9163e2c 303 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 138 299 4.0E-24 T 12-10-2018 IPR005642 Lysine exporter LysO MIM_c32830 24a9115db4b425af3fecd742b639c058 276 Gene3D G3DSA:3.40.50.10490 100 274 6.2E-34 T 12-10-2018 MIM_c32830 24a9115db4b425af3fecd742b639c058 276 SUPERFAMILY SSF53697 103 262 4.89E-31 T 12-10-2018 MIM_c32830 24a9115db4b425af3fecd742b639c058 276 Gene3D G3DSA:1.10.10.10 5 87 1.3E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c32830 24a9115db4b425af3fecd742b639c058 276 Pfam PF01380 SIS domain 129 230 2.7E-16 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MIM_c32830 24a9115db4b425af3fecd742b639c058 276 Pfam PF01418 Helix-turn-helix domain, rpiR family 16 83 2.3E-17 T 12-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 MIM_c32830 24a9115db4b425af3fecd742b639c058 276 SUPERFAMILY SSF46689 13 82 1.06E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c01590 d30b75fa1ca420c48c5179481cb07c19 210 Gene3D G3DSA:1.10.760.10 47 182 9.8E-57 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c01590 d30b75fa1ca420c48c5179481cb07c19 210 SUPERFAMILY SSF46626 51 183 2.26E-20 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c01590 d30b75fa1ca420c48c5179481cb07c19 210 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 71 153 6.8E-11 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c28420 5ddf74074d2012804a5f6eafd5b1aa98 258 SMART SM00345 12 71 1.5E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c28420 5ddf74074d2012804a5f6eafd5b1aa98 258 Gene3D G3DSA:1.10.10.10 4 78 5.1E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c28420 5ddf74074d2012804a5f6eafd5b1aa98 258 SUPERFAMILY SSF46785 7 75 5.99E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c28420 5ddf74074d2012804a5f6eafd5b1aa98 258 Gene3D G3DSA:1.20.120.530 91 248 6.9E-25 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c28420 5ddf74074d2012804a5f6eafd5b1aa98 258 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 2.4E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c28420 5ddf74074d2012804a5f6eafd5b1aa98 258 SUPERFAMILY SSF48008 92 245 1.36E-20 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c28420 5ddf74074d2012804a5f6eafd5b1aa98 258 Pfam PF07729 FCD domain 96 239 6.0E-19 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c28420 5ddf74074d2012804a5f6eafd5b1aa98 258 SMART SM00895 95 240 3.1E-23 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c09880 a7c5bdd4d02cc2c35fd979dbeea63f34 666 Gene3D G3DSA:3.50.50.60 580 666 2.5E-12 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c09880 a7c5bdd4d02cc2c35fd979dbeea63f34 666 Gene3D G3DSA:3.30.9.10 436 551 9.2E-7 T 12-10-2018 MIM_c09880 a7c5bdd4d02cc2c35fd979dbeea63f34 666 SUPERFAMILY SSF51905 240 656 1.55E-21 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c09880 a7c5bdd4d02cc2c35fd979dbeea63f34 666 Pfam PF01266 FAD dependent oxidoreductase 240 647 2.2E-23 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MIM_c09880 a7c5bdd4d02cc2c35fd979dbeea63f34 666 Gene3D G3DSA:3.50.50.60 224 369 1.2E-17 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c30340 2efe70b0aaf7ebf93d87c4617f688cde 142 Pfam PF03960 ArsC family 35 113 2.9E-15 T 12-10-2018 IPR006660 Arsenate reductase-like MIM_c30340 2efe70b0aaf7ebf93d87c4617f688cde 142 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 3 115 8.6E-45 T 12-10-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 MIM_c30340 2efe70b0aaf7ebf93d87c4617f688cde 142 SUPERFAMILY SSF52833 2 129 5.22E-37 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c30340 2efe70b0aaf7ebf93d87c4617f688cde 142 Gene3D G3DSA:3.40.30.10 1 140 1.1E-52 T 12-10-2018 MIM_c33150 2cb622b9c9cc1ff81c17122f2b20544e 197 Pfam PF04191 Phospholipid methyltransferase 61 130 6.1E-12 T 12-10-2018 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 MIM_c33150 2cb622b9c9cc1ff81c17122f2b20544e 197 Gene3D G3DSA:1.20.120.1630 2 142 1.0E-22 T 12-10-2018 MIM_c26690 8a648aef71dead8458f456cf81e5b6dc 500 SUPERFAMILY SSF109998 47 240 1.41E-37 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily MIM_c26690 8a648aef71dead8458f456cf81e5b6dc 500 Gene3D G3DSA:1.10.4030.30 43 208 4.9E-39 T 12-10-2018 MIM_c26690 8a648aef71dead8458f456cf81e5b6dc 500 Pfam PF13616 PPIC-type PPIASE domain 340 449 5.7E-25 T 12-10-2018 MIM_c26690 8a648aef71dead8458f456cf81e5b6dc 500 Pfam PF09312 SurA N-terminal domain 47 156 6.8E-21 T 12-10-2018 IPR015391 SurA N-terminal MIM_c26690 8a648aef71dead8458f456cf81e5b6dc 500 Pfam PF00639 PPIC-type PPIASE domain 217 310 1.3E-15 T 12-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 MIM_c26690 8a648aef71dead8458f456cf81e5b6dc 500 SUPERFAMILY SSF54534 352 450 2.03E-29 T 12-10-2018 MIM_c26690 8a648aef71dead8458f456cf81e5b6dc 500 SUPERFAMILY SSF54534 213 314 6.54E-22 T 12-10-2018 MIM_c26690 8a648aef71dead8458f456cf81e5b6dc 500 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 388 408 - T 12-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 MIM_c26690 8a648aef71dead8458f456cf81e5b6dc 500 Hamap MF_01183 Chaperone SurA [surA]. 17 494 27.644 T 12-10-2018 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0043165|GO:0050821|GO:0051082|GO:0060274 MIM_c09920 2705f73b698152d5534d5f8579635cb5 395 Gene3D G3DSA:1.20.1250.20 207 394 2.1E-22 T 12-10-2018 MIM_c09920 2705f73b698152d5534d5f8579635cb5 395 Pfam PF07690 Major Facilitator Superfamily 219 390 1.8E-14 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c09920 2705f73b698152d5534d5f8579635cb5 395 Pfam PF07690 Major Facilitator Superfamily 20 189 4.2E-19 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c09920 2705f73b698152d5534d5f8579635cb5 395 Gene3D G3DSA:1.20.1250.20 11 204 4.2E-21 T 12-10-2018 MIM_c09920 2705f73b698152d5534d5f8579635cb5 395 SUPERFAMILY SSF103473 19 392 1.31E-48 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c15700 db634be2615da356cee5ac7d840b988c 1026 Gene3D G3DSA:3.40.50.300 865 1012 5.9E-21 T 12-10-2018 MIM_c15700 db634be2615da356cee5ac7d840b988c 1026 Pfam PF13558 Putative exonuclease SbcCD, C subunit 909 972 1.7E-12 T 12-10-2018 MIM_c15700 db634be2615da356cee5ac7d840b988c 1026 Gene3D G3DSA:3.40.50.300 1 262 4.5E-37 T 12-10-2018 MIM_c15700 db634be2615da356cee5ac7d840b988c 1026 Pfam PF13476 AAA domain 6 226 6.0E-18 T 12-10-2018 IPR038729 Rad50/SbcC-type AAA domain MIM_c15700 db634be2615da356cee5ac7d840b988c 1026 SUPERFAMILY SSF52540 6 1003 1.15E-29 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c27330 4d8ab32e509e5320d35f8bfb62549b12 539 SUPERFAMILY SSF47090 198 275 1.33E-12 T 12-10-2018 IPR036365 PGBD-like superfamily MIM_c27330 4d8ab32e509e5320d35f8bfb62549b12 539 Pfam PF01471 Putative peptidoglycan binding domain 219 267 1.1E-6 T 12-10-2018 IPR002477 Peptidoglycan binding-like MIM_c27330 4d8ab32e509e5320d35f8bfb62549b12 539 Pfam PF03734 L,D-transpeptidase catalytic domain 295 467 2.1E-28 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 MIM_c27330 4d8ab32e509e5320d35f8bfb62549b12 539 SUPERFAMILY SSF141523 293 454 1.83E-14 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like MIM_c27330 4d8ab32e509e5320d35f8bfb62549b12 539 Gene3D G3DSA:2.40.440.10 240 491 4.7E-25 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like MIM_c10080 ec5ca5d7deec38d7782c22070e271693 357 Gene3D G3DSA:3.30.9.10 88 308 6.6E-49 T 12-10-2018 MIM_c10080 ec5ca5d7deec38d7782c22070e271693 357 Pfam PF01266 FAD dependent oxidoreductase 3 338 4.0E-31 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MIM_c10080 ec5ca5d7deec38d7782c22070e271693 357 SUPERFAMILY SSF51905 3 215 5.31E-21 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c10080 ec5ca5d7deec38d7782c22070e271693 357 SUPERFAMILY SSF54373 218 307 3.01E-16 T 12-10-2018 MIM_c10080 ec5ca5d7deec38d7782c22070e271693 357 Gene3D G3DSA:3.50.50.60 4 338 6.6E-49 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c30480 ed4da19aac5513f42b5f6dd2fbe593e0 243 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c30480 ed4da19aac5513f42b5f6dd2fbe593e0 243 PIRSF PIRSF039085 1 243 8.3E-99 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MIM_c30480 ed4da19aac5513f42b5f6dd2fbe593e0 243 SMART SM00382 29 215 3.1E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c30480 ed4da19aac5513f42b5f6dd2fbe593e0 243 Gene3D G3DSA:3.40.50.300 1 243 1.6E-72 T 12-10-2018 MIM_c30480 ed4da19aac5513f42b5f6dd2fbe593e0 243 Pfam PF00005 ABC transporter 20 167 1.3E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c30480 ed4da19aac5513f42b5f6dd2fbe593e0 243 SUPERFAMILY SSF52540 4 237 7.22E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c36590 5420d1e734b72b61a6d4f29154e66da2 569 Gene3D G3DSA:3.40.50.410 352 565 4.3E-6 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily MIM_c36590 5420d1e734b72b61a6d4f29154e66da2 569 SUPERFAMILY SSF53300 362 550 1.63E-8 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily MIM_c36590 5420d1e734b72b61a6d4f29154e66da2 569 Pfam PF06213 Cobalamin biosynthesis protein CobT 19 223 3.9E-22 T 12-10-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 MIM_c36590 5420d1e734b72b61a6d4f29154e66da2 569 Pfam PF11775 Cobalamin biosynthesis protein CobT VWA domain 350 564 6.0E-44 T 12-10-2018 IPR025861 Cobalamin biosynthesis protein CobT VWA domain KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 MIM_c36590 5420d1e734b72b61a6d4f29154e66da2 569 PIRSF PIRSF031715 239 569 5.6E-75 T 12-10-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 MIM_c36590 5420d1e734b72b61a6d4f29154e66da2 569 PIRSF PIRSF031715 6 230 3.4E-18 T 12-10-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 MIM_c16000 2f763fde43910c0439abd120d1592182 321 Pfam PF06574 FAD synthetase 15 175 7.2E-47 T 12-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 MIM_c16000 2f763fde43910c0439abd120d1592182 321 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 21 316 1.4E-83 T 12-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 MIM_c16000 2f763fde43910c0439abd120d1592182 321 SMART SM00904 192 317 8.1E-48 T 12-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 MIM_c16000 2f763fde43910c0439abd120d1592182 321 Gene3D G3DSA:3.40.50.620 7 195 5.3E-54 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c16000 2f763fde43910c0439abd120d1592182 321 PIRSF PIRSF004491 5 320 1.2E-90 T 12-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 MIM_c16000 2f763fde43910c0439abd120d1592182 321 Gene3D G3DSA:2.40.30.30 197 319 4.3E-33 T 12-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 MIM_c16000 2f763fde43910c0439abd120d1592182 321 SUPERFAMILY SSF82114 184 317 1.05E-36 T 12-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 MIM_c16000 2f763fde43910c0439abd120d1592182 321 Pfam PF01687 Riboflavin kinase 193 316 1.5E-32 T 12-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 MIM_c16000 2f763fde43910c0439abd120d1592182 321 SUPERFAMILY SSF52374 20 185 7.29E-26 T 12-10-2018 MIM_c40860 b42aed8a14ce3268aaf4fb8ff229123d 207 Gene3D G3DSA:1.20.120.530 74 207 5.4E-25 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c40860 b42aed8a14ce3268aaf4fb8ff229123d 207 SUPERFAMILY SSF46785 11 74 5.06E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c40860 b42aed8a14ce3268aaf4fb8ff229123d 207 SUPERFAMILY SSF48008 76 205 3.66E-22 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c40860 b42aed8a14ce3268aaf4fb8ff229123d 207 SMART SM00895 80 204 3.7E-17 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c40860 b42aed8a14ce3268aaf4fb8ff229123d 207 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 70 2.0E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c40860 b42aed8a14ce3268aaf4fb8ff229123d 207 Pfam PF07729 FCD domain 82 203 8.3E-24 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c40860 b42aed8a14ce3268aaf4fb8ff229123d 207 Gene3D G3DSA:1.10.10.10 10 70 8.2E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c06050 2de160044f5e12fcf5e07647e9db3f9b 280 SMART SM00382 29 229 9.1E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c06050 2de160044f5e12fcf5e07647e9db3f9b 280 Pfam PF00005 ABC transporter 20 181 3.1E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c06050 2de160044f5e12fcf5e07647e9db3f9b 280 SUPERFAMILY SSF52540 4 243 1.21E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c06050 2de160044f5e12fcf5e07647e9db3f9b 280 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c06050 2de160044f5e12fcf5e07647e9db3f9b 280 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 5 250 3.2E-88 T 12-10-2018 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 MIM_c06050 2de160044f5e12fcf5e07647e9db3f9b 280 Gene3D G3DSA:3.40.50.300 4 254 3.4E-63 T 12-10-2018 MIM_c04950 f587826f87dd75db750beaf068717ea4 383 SMART SM00228 282 364 6.3E-13 T 12-10-2018 IPR001478 PDZ domain GO:0005515 MIM_c04950 f587826f87dd75db750beaf068717ea4 383 Pfam PF13365 Trypsin-like peptidase domain 107 241 7.4E-29 T 12-10-2018 MIM_c04950 f587826f87dd75db750beaf068717ea4 383 SUPERFAMILY SSF50156 253 377 1.58E-22 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 MIM_c04950 f587826f87dd75db750beaf068717ea4 383 Gene3D G3DSA:2.40.10.120 53 276 6.6E-73 T 12-10-2018 MIM_c04950 f587826f87dd75db750beaf068717ea4 383 Pfam PF13180 PDZ domain 283 373 2.6E-16 T 12-10-2018 IPR001478 PDZ domain GO:0005515 MIM_c04950 f587826f87dd75db750beaf068717ea4 383 PRINTS PR00834 HtrA/DegQ protease family signature 177 201 1.8E-52 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MIM_c04950 f587826f87dd75db750beaf068717ea4 383 PRINTS PR00834 HtrA/DegQ protease family signature 322 334 1.8E-52 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MIM_c04950 f587826f87dd75db750beaf068717ea4 383 PRINTS PR00834 HtrA/DegQ protease family signature 116 128 1.8E-52 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MIM_c04950 f587826f87dd75db750beaf068717ea4 383 PRINTS PR00834 HtrA/DegQ protease family signature 137 157 1.8E-52 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MIM_c04950 f587826f87dd75db750beaf068717ea4 383 PRINTS PR00834 HtrA/DegQ protease family signature 212 229 1.8E-52 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MIM_c04950 f587826f87dd75db750beaf068717ea4 383 PRINTS PR00834 HtrA/DegQ protease family signature 234 251 1.8E-52 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MIM_c04950 f587826f87dd75db750beaf068717ea4 383 SUPERFAMILY SSF50494 53 278 5.54E-61 T 12-10-2018 IPR009003 Peptidase S1, PA clan MIM_c04950 f587826f87dd75db750beaf068717ea4 383 Gene3D G3DSA:2.30.42.10 277 381 1.0E-25 T 12-10-2018 MIM_c08690 d62e63cf514152d73e5d73ee1df04be4 345 Gene3D G3DSA:3.40.190.10 33 311 1.3E-82 T 12-10-2018 MIM_c08690 d62e63cf514152d73e5d73ee1df04be4 345 Gene3D G3DSA:3.40.190.10 129 325 1.3E-82 T 12-10-2018 MIM_c08690 d62e63cf514152d73e5d73ee1df04be4 345 SUPERFAMILY SSF53850 26 341 8.03E-57 T 12-10-2018 MIM_c08690 d62e63cf514152d73e5d73ee1df04be4 345 Pfam PF13416 Bacterial extracellular solute-binding protein 46 306 4.9E-30 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein MIM_c38300 44467f0f8ee5a2a710a08cd7fd3d6f58 259 Gene3D G3DSA:1.20.1290.10 1 127 2.3E-25 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c38300 44467f0f8ee5a2a710a08cd7fd3d6f58 259 Gene3D G3DSA:1.20.1290.10 128 259 1.6E-12 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c38300 44467f0f8ee5a2a710a08cd7fd3d6f58 259 SUPERFAMILY SSF69118 5 247 6.89E-31 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c17920 b1ab46f126e212faaf3da3df8e666ecd 487 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 8 477 2.2E-168 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 MIM_c17920 b1ab46f126e212faaf3da3df8e666ecd 487 Pfam PF01926 50S ribosome-binding GTPase 10 125 4.9E-24 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 MIM_c17920 b1ab46f126e212faaf3da3df8e666ecd 487 Pfam PF01926 50S ribosome-binding GTPase 224 341 7.7E-24 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 MIM_c17920 b1ab46f126e212faaf3da3df8e666ecd 487 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 397 477 7.7E-25 T 12-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like MIM_c17920 b1ab46f126e212faaf3da3df8e666ecd 487 Gene3D G3DSA:3.40.50.300 217 393 1.8E-47 T 12-10-2018 MIM_c17920 b1ab46f126e212faaf3da3df8e666ecd 487 SUPERFAMILY SSF52540 143 484 2.8E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c17920 b1ab46f126e212faaf3da3df8e666ecd 487 PIRSF PIRSF006485 6 485 9.7E-166 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 MIM_c17920 b1ab46f126e212faaf3da3df8e666ecd 487 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 10 30 1.1E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 MIM_c17920 b1ab46f126e212faaf3da3df8e666ecd 487 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 78 96 1.1E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 MIM_c17920 b1ab46f126e212faaf3da3df8e666ecd 487 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 221 385 4.5E-24 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MIM_c17920 b1ab46f126e212faaf3da3df8e666ecd 487 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 130 6.3E-17 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MIM_c17920 b1ab46f126e212faaf3da3df8e666ecd 487 Gene3D G3DSA:3.40.50.300 6 165 1.8E-38 T 12-10-2018 MIM_c17920 b1ab46f126e212faaf3da3df8e666ecd 487 SUPERFAMILY SSF52540 9 178 1.84E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c17920 b1ab46f126e212faaf3da3df8e666ecd 487 Hamap MF_00195 GTPase Der [der]. 7 480 37.327 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 MIM_c17920 b1ab46f126e212faaf3da3df8e666ecd 487 Gene3D G3DSA:3.30.300.20 397 480 2.2E-20 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta MIM_c30090 a42c51b153ff16dc18c50dcc9ce5b785 331 Gene3D G3DSA:3.40.50.1980 141 314 3.9E-50 T 12-10-2018 MIM_c30090 a42c51b153ff16dc18c50dcc9ce5b785 331 SUPERFAMILY SSF53807 50 311 7.85E-49 T 12-10-2018 MIM_c30090 a42c51b153ff16dc18c50dcc9ce5b785 331 Gene3D G3DSA:3.40.50.1980 48 138 2.4E-17 T 12-10-2018 MIM_c30090 a42c51b153ff16dc18c50dcc9ce5b785 331 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 103 118 1.6E-10 T 12-10-2018 MIM_c30090 a42c51b153ff16dc18c50dcc9ce5b785 331 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 72 90 1.6E-10 T 12-10-2018 MIM_c30090 a42c51b153ff16dc18c50dcc9ce5b785 331 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 292 305 1.6E-10 T 12-10-2018 MIM_c30090 a42c51b153ff16dc18c50dcc9ce5b785 331 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 202 217 1.6E-10 T 12-10-2018 MIM_c30090 a42c51b153ff16dc18c50dcc9ce5b785 331 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 226 244 1.6E-10 T 12-10-2018 MIM_c30090 a42c51b153ff16dc18c50dcc9ce5b785 331 Pfam PF01497 Periplasmic binding protein 55 290 3.0E-19 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain MIM_c12890 68ec98572ba37c7aea44d75779ca7bc7 309 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 28 41 - T 12-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 MIM_c12890 68ec98572ba37c7aea44d75779ca7bc7 309 SUPERFAMILY SSF53686 2 292 2.36E-66 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MIM_c12890 68ec98572ba37c7aea44d75779ca7bc7 309 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 3 290 2.2E-63 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MIM_c12890 68ec98572ba37c7aea44d75779ca7bc7 309 Gene3D G3DSA:3.40.50.1100 38 131 2.3E-102 T 12-10-2018 MIM_c12890 68ec98572ba37c7aea44d75779ca7bc7 309 Gene3D G3DSA:3.40.50.1100 7 294 2.3E-102 T 12-10-2018 MIM_c37800 ec6fecf4f252112e00b828cc3bc31316 378 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 371 4.8E-161 T 12-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 MIM_c37800 ec6fecf4f252112e00b828cc3bc31316 378 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 23 369 1.8E-121 T 12-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MIM_c37800 ec6fecf4f252112e00b828cc3bc31316 378 Gene3D G3DSA:3.40.50.2000 187 356 1.5E-150 T 12-10-2018 MIM_c37800 ec6fecf4f252112e00b828cc3bc31316 378 SUPERFAMILY SSF53756 1 371 3.1E-134 T 12-10-2018 MIM_c37800 ec6fecf4f252112e00b828cc3bc31316 378 Gene3D G3DSA:3.40.50.2000 2 367 1.5E-150 T 12-10-2018 MIM_c31830 da79ae06c2dbfa6a620f56d175712238 305 SUPERFAMILY SSF46785 8 87 4.54E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c31830 da79ae06c2dbfa6a620f56d175712238 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 69 3.8E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c31830 da79ae06c2dbfa6a620f56d175712238 305 Pfam PF03466 LysR substrate binding domain 96 302 4.1E-20 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c31830 da79ae06c2dbfa6a620f56d175712238 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 2.8E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c31830 da79ae06c2dbfa6a620f56d175712238 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 2.8E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c31830 da79ae06c2dbfa6a620f56d175712238 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 2.8E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c31830 da79ae06c2dbfa6a620f56d175712238 305 Gene3D G3DSA:3.40.190.10 173 280 7.8E-13 T 12-10-2018 MIM_c31830 da79ae06c2dbfa6a620f56d175712238 305 Gene3D G3DSA:1.10.10.10 8 97 3.6E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c31830 da79ae06c2dbfa6a620f56d175712238 305 SUPERFAMILY SSF53850 96 304 4.16E-20 T 12-10-2018 MIM_c31830 da79ae06c2dbfa6a620f56d175712238 305 Gene3D G3DSA:3.40.190.10 99 293 7.8E-13 T 12-10-2018 MIM_c13240 8ff9fe45ec18b5860a1357b3faf8b7cb 125 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 13 115 1.7E-11 T 12-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MIM_c13240 8ff9fe45ec18b5860a1357b3faf8b7cb 125 Gene3D G3DSA:1.20.1300.10 9 125 1.4E-24 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MIM_c13240 8ff9fe45ec18b5860a1357b3faf8b7cb 125 PIRSF PIRSF000169 7 125 4.0E-36 T 12-10-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 MIM_c13240 8ff9fe45ec18b5860a1357b3faf8b7cb 125 SUPERFAMILY SSF81343 10 125 1.18E-22 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MIM_c13240 8ff9fe45ec18b5860a1357b3faf8b7cb 125 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 16 123 2.8E-32 T 12-10-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 MIM_c32630 ebfb8c8ccde33bf662c0210748c5be4d 140 SUPERFAMILY SSF82784 1 137 1.44E-39 T 12-10-2018 IPR036102 OsmC/Ohr superfamily MIM_c32630 ebfb8c8ccde33bf662c0210748c5be4d 140 Pfam PF02566 OsmC-like protein 35 132 6.0E-17 T 12-10-2018 IPR003718 OsmC/Ohr family MIM_c32630 ebfb8c8ccde33bf662c0210748c5be4d 140 Gene3D G3DSA:2.20.25.10 1 39 2.3E-5 T 12-10-2018 MIM_c32630 ebfb8c8ccde33bf662c0210748c5be4d 140 Gene3D G3DSA:3.30.300.20 41 139 2.1E-31 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta MIM_c22350 952d44d926720aab13a60e1c2393a9fd 295 SMART SM00345 20 79 1.0E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c22350 952d44d926720aab13a60e1c2393a9fd 295 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 1.1E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c22350 952d44d926720aab13a60e1c2393a9fd 295 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 1.1E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c22350 952d44d926720aab13a60e1c2393a9fd 295 Gene3D G3DSA:1.10.10.10 15 124 1.7E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c22350 952d44d926720aab13a60e1c2393a9fd 295 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 79 6.6E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c22350 952d44d926720aab13a60e1c2393a9fd 295 Gene3D G3DSA:1.20.120.530 153 295 4.7E-24 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c22350 952d44d926720aab13a60e1c2393a9fd 295 SMART SM00895 154 285 1.7E-18 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c22350 952d44d926720aab13a60e1c2393a9fd 295 SUPERFAMILY SSF48008 151 293 1.18E-24 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c22350 952d44d926720aab13a60e1c2393a9fd 295 SUPERFAMILY SSF46785 13 83 2.08E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c22350 952d44d926720aab13a60e1c2393a9fd 295 Pfam PF07729 FCD domain 156 284 5.5E-21 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c25710 c72c2b28608a875d5004013a56ab6631 299 Pfam PF00950 ABC 3 transport family 25 286 4.7E-50 T 12-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 MIM_c25710 c72c2b28608a875d5004013a56ab6631 299 SUPERFAMILY SSF81345 13 283 1.96E-29 T 12-10-2018 IPR037294 ABC transporter, BtuC-like MIM_c25710 c72c2b28608a875d5004013a56ab6631 299 PRINTS PR01035 Tetracycline resistance protein signature 244 267 4.9E-5 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MIM_c25710 c72c2b28608a875d5004013a56ab6631 299 PRINTS PR01035 Tetracycline resistance protein signature 25 47 4.9E-5 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MIM_c24290 d59b041012caf35466df9c357ac60dda 367 SUPERFAMILY SSF64383 242 350 1.83E-10 T 12-10-2018 IPR036765 ZipA, C-terminal FtsZ-binding domain superfamily GO:0090529 MIM_c24290 d59b041012caf35466df9c357ac60dda 367 SMART SM00771 223 343 1.1E-4 T 12-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 MIM_c24290 d59b041012caf35466df9c357ac60dda 367 Pfam PF04354 ZipA, C-terminal FtsZ-binding domain 287 339 6.3E-6 T 12-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 MIM_c35700 4e9e383f47333f17f3f7f682d9e17193 350 SUPERFAMILY SSF141571 18 168 1.07E-32 T 12-10-2018 MIM_c35700 4e9e383f47333f17f3f7f682d9e17193 350 Pfam PF13599 Pentapeptide repeats (9 copies) 133 206 1.0E-11 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c35700 4e9e383f47333f17f3f7f682d9e17193 350 Pfam PF13599 Pentapeptide repeats (9 copies) 213 277 1.8E-8 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c35700 4e9e383f47333f17f3f7f682d9e17193 350 Gene3D G3DSA:2.160.20.80 126 248 4.0E-23 T 12-10-2018 MIM_c35700 4e9e383f47333f17f3f7f682d9e17193 350 Gene3D G3DSA:2.160.20.100 249 348 3.9E-12 T 12-10-2018 MIM_c35700 4e9e383f47333f17f3f7f682d9e17193 350 SUPERFAMILY SSF141571 156 320 4.12E-33 T 12-10-2018 MIM_c35700 4e9e383f47333f17f3f7f682d9e17193 350 Gene3D G3DSA:2.160.20.100 2 125 9.1E-23 T 12-10-2018 MIM_c35700 4e9e383f47333f17f3f7f682d9e17193 350 Pfam PF00805 Pentapeptide repeats (8 copies) 81 112 0.0092 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c35700 4e9e383f47333f17f3f7f682d9e17193 350 Pfam PF00805 Pentapeptide repeats (8 copies) 40 76 2.8E-9 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c26650 904a62daec1410307fc6332e5f04c6ef 137 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 2 130 1.3E-63 T 12-10-2018 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 MIM_c26650 904a62daec1410307fc6332e5f04c6ef 137 SUPERFAMILY SSF54593 1 128 6.04E-34 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c26650 904a62daec1410307fc6332e5f04c6ef 137 Gene3D G3DSA:3.10.180.10 1 132 1.4E-47 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c26650 904a62daec1410307fc6332e5f04c6ef 137 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 123 1.1E-19 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MIM_c18790 e76f57537d66afae2347579750a95445 282 SMART SM00481 9 74 8.4E-16 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal MIM_c18790 e76f57537d66afae2347579750a95445 282 Gene3D G3DSA:3.20.20.140 10 255 1.6E-91 T 12-10-2018 MIM_c18790 e76f57537d66afae2347579750a95445 282 Gene3D G3DSA:1.10.150.650 102 174 1.6E-91 T 12-10-2018 MIM_c18790 e76f57537d66afae2347579750a95445 282 SUPERFAMILY SSF89550 7 280 5.3E-50 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MIM_c18790 e76f57537d66afae2347579750a95445 282 Pfam PF02811 PHP domain 10 163 2.7E-8 T 12-10-2018 IPR004013 PHP domain GO:0003824 MIM_c01800 cca4104baaaaa0473240345e36071596 696 Pfam PF00593 TonB dependent receptor 225 695 1.9E-57 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MIM_c01800 cca4104baaaaa0473240345e36071596 696 SUPERFAMILY SSF56935 44 696 5.04E-127 T 12-10-2018 MIM_c01800 cca4104baaaaa0473240345e36071596 696 Pfam PF07715 TonB-dependent Receptor Plug Domain 57 167 6.6E-25 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain MIM_c01800 cca4104baaaaa0473240345e36071596 696 Gene3D G3DSA:2.170.130.10 41 172 6.8E-40 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MIM_c01800 cca4104baaaaa0473240345e36071596 696 Gene3D G3DSA:2.40.170.20 178 696 1.0E-126 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MIM_c08310 c8fa0ed87bdaa271084dea2dab9c9bed 242 SMART SM00382 29 216 1.3E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c08310 c8fa0ed87bdaa271084dea2dab9c9bed 242 Pfam PF00005 ABC transporter 20 168 1.3E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c08310 c8fa0ed87bdaa271084dea2dab9c9bed 242 SUPERFAMILY SSF52540 4 233 1.94E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c08310 c8fa0ed87bdaa271084dea2dab9c9bed 242 Gene3D G3DSA:3.40.50.300 2 240 9.5E-76 T 12-10-2018 MIM_c08310 c8fa0ed87bdaa271084dea2dab9c9bed 242 PIRSF PIRSF039085 1 242 1.5E-103 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MIM_c08310 c8fa0ed87bdaa271084dea2dab9c9bed 242 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c28120 90010f50c1d09c66ebe2b2e086cd7d78 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.2E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c28120 90010f50c1d09c66ebe2b2e086cd7d78 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.2E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c28120 90010f50c1d09c66ebe2b2e086cd7d78 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.2E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c28120 90010f50c1d09c66ebe2b2e086cd7d78 297 SUPERFAMILY SSF46785 3 112 4.06E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c28120 90010f50c1d09c66ebe2b2e086cd7d78 297 Pfam PF03466 LysR substrate binding domain 89 292 4.5E-51 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c28120 90010f50c1d09c66ebe2b2e086cd7d78 297 SUPERFAMILY SSF53850 91 295 5.98E-51 T 12-10-2018 MIM_c28120 90010f50c1d09c66ebe2b2e086cd7d78 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 1.8E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c28120 90010f50c1d09c66ebe2b2e086cd7d78 297 Gene3D G3DSA:3.40.190.290 93 296 3.7E-56 T 12-10-2018 MIM_c28120 90010f50c1d09c66ebe2b2e086cd7d78 297 Gene3D G3DSA:1.10.10.10 3 91 4.0E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c35850 30cc6507ebc698e11bb0954ce4c4ddc5 230 Gene3D G3DSA:3.40.1080.10 1 224 4.4E-78 T 12-10-2018 MIM_c35850 30cc6507ebc698e11bb0954ce4c4ddc5 230 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 219 3.3E-117 T 12-10-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 MIM_c35850 30cc6507ebc698e11bb0954ce4c4ddc5 230 SUPERFAMILY SSF100950 2 221 1.05E-77 T 12-10-2018 IPR037171 NagB/RpiA transferase-like MIM_c35850 30cc6507ebc698e11bb0954ce4c4ddc5 230 SMART SM00882 6 219 4.4E-78 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MIM_c35850 30cc6507ebc698e11bb0954ce4c4ddc5 230 Pfam PF01144 Coenzyme A transferase 8 218 4.9E-70 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MIM_c09240 c38871a70173ee0bd700c81da72753ba 1038 Gene3D G3DSA:3.30.70.1440 654 851 9.4E-298 T 12-10-2018 MIM_c09240 c38871a70173ee0bd700c81da72753ba 1038 SUPERFAMILY SSF82866 794 1017 9.02E-46 T 12-10-2018 MIM_c09240 c38871a70173ee0bd700c81da72753ba 1038 Gene3D G3DSA:1.20.1640.10 10 503 9.4E-298 T 12-10-2018 MIM_c09240 c38871a70173ee0bd700c81da72753ba 1038 Gene3D G3DSA:3.30.70.1320 135 326 9.4E-298 T 12-10-2018 MIM_c09240 c38871a70173ee0bd700c81da72753ba 1038 Gene3D G3DSA:3.30.70.1430 40 801 9.4E-298 T 12-10-2018 MIM_c09240 c38871a70173ee0bd700c81da72753ba 1038 SUPERFAMILY SSF82714 183 264 7.72E-16 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c09240 c38871a70173ee0bd700c81da72753ba 1038 Gene3D G3DSA:3.30.2090.10 179 269 9.4E-298 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c09240 c38871a70173ee0bd700c81da72753ba 1038 SUPERFAMILY SSF82693 137 324 2.62E-24 T 12-10-2018 MIM_c09240 c38871a70173ee0bd700c81da72753ba 1038 SUPERFAMILY SSF82693 556 650 2.07E-14 T 12-10-2018 MIM_c09240 c38871a70173ee0bd700c81da72753ba 1038 Pfam PF00873 AcrB/AcrD/AcrF family 3 1012 0.0 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09240 c38871a70173ee0bd700c81da72753ba 1038 Gene3D G3DSA:3.30.2090.10 705 793 9.4E-298 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c09240 c38871a70173ee0bd700c81da72753ba 1038 PRINTS PR00702 Acriflavin resistance protein family signature 610 624 1.6E-74 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09240 c38871a70173ee0bd700c81da72753ba 1038 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.6E-74 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09240 c38871a70173ee0bd700c81da72753ba 1038 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 1.6E-74 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09240 c38871a70173ee0bd700c81da72753ba 1038 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 1.6E-74 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09240 c38871a70173ee0bd700c81da72753ba 1038 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 1.6E-74 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09240 c38871a70173ee0bd700c81da72753ba 1038 PRINTS PR00702 Acriflavin resistance protein family signature 543 560 1.6E-74 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09240 c38871a70173ee0bd700c81da72753ba 1038 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.6E-74 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09240 c38871a70173ee0bd700c81da72753ba 1038 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 1.6E-74 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09240 c38871a70173ee0bd700c81da72753ba 1038 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 1.6E-74 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c09240 c38871a70173ee0bd700c81da72753ba 1038 SUPERFAMILY SSF82693 40 134 1.73E-22 T 12-10-2018 MIM_c09240 c38871a70173ee0bd700c81da72753ba 1038 SUPERFAMILY SSF82714 707 792 6.28E-19 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c09240 c38871a70173ee0bd700c81da72753ba 1038 Gene3D G3DSA:1.20.1640.10 504 1009 9.4E-298 T 12-10-2018 MIM_c09240 c38871a70173ee0bd700c81da72753ba 1038 SUPERFAMILY SSF82866 290 490 1.83E-48 T 12-10-2018 MIM_c09240 c38871a70173ee0bd700c81da72753ba 1038 Gene3D G3DSA:3.30.70.1430 558 653 9.4E-298 T 12-10-2018 MIM_c20460 41e2968f4ff4096c9ae9daebce14cebf 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.6E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20460 41e2968f4ff4096c9ae9daebce14cebf 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.6E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20460 41e2968f4ff4096c9ae9daebce14cebf 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.6E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20460 41e2968f4ff4096c9ae9daebce14cebf 253 SUPERFAMILY SSF51735 6 252 6.67E-84 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c20460 41e2968f4ff4096c9ae9daebce14cebf 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 251 7.8E-71 T 12-10-2018 MIM_c20460 41e2968f4ff4096c9ae9daebce14cebf 253 Gene3D G3DSA:3.40.50.720 2 252 3.3E-87 T 12-10-2018 MIM_c20460 41e2968f4ff4096c9ae9daebce14cebf 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 192 5.5E-4 T 12-10-2018 MIM_c20460 41e2968f4ff4096c9ae9daebce14cebf 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 4.0E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20460 41e2968f4ff4096c9ae9daebce14cebf 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 4.0E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20460 41e2968f4ff4096c9ae9daebce14cebf 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 4.0E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20460 41e2968f4ff4096c9ae9daebce14cebf 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 4.0E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20460 41e2968f4ff4096c9ae9daebce14cebf 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 4.0E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20460 41e2968f4ff4096c9ae9daebce14cebf 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.0E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 SUPERFAMILY SSF101967 1644 1744 2.09E-6 T 12-10-2018 MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Pfam PF13018 Extended Signal Peptide of Type V secretion system 1 24 4.4E-9 T 12-10-2018 IPR024973 ESPR domain MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Gene3D G3DSA:2.150.10.10 675 787 3.8E-8 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Gene3D G3DSA:2.150.10.10 889 1000 7.1E-6 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Gene3D G3DSA:2.150.10.10 1314 1426 7.3E-7 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 SUPERFAMILY SSF54523 1734 1833 5.02E-25 T 12-10-2018 MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Gene3D G3DSA:3.30.1300.30 1756 1833 9.9E-30 T 12-10-2018 MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 649 692 5.4E-11 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1288 1331 2.1E-9 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1501 1543 1.4E-8 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 436 479 5.2E-8 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1075 1118 8.2E-11 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1403 1443 7.5E-11 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1190 1226 4.7E-7 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1612 1651 3.8E-7 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 338 374 9.9E-8 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 764 800 2.2E-10 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 977 1017 2.4E-9 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 862 905 1.2E-10 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 223 255 4.1E-9 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1722 1753 6.9E-8 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 551 587 1.7E-7 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 SUPERFAMILY SSF101967 1099 1211 6.02E-5 T 12-10-2018 MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 SUPERFAMILY SSF101967 122 246 3.79E-12 T 12-10-2018 MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 SUPERFAMILY SSF101967 1320 1424 1.44E-6 T 12-10-2018 MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Gene3D G3DSA:2.150.10.10 583 674 1.4E-7 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Gene3D G3DSA:2.150.10.10 1439 1529 2.7E-7 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Gene3D G3DSA:2.150.10.10 1005 1103 5.4E-8 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Gene3D G3DSA:2.150.10.10 1236 1313 9.4E-7 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Gene3D G3DSA:2.150.10.10 1540 1638 3.7E-8 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Gene3D G3DSA:2.150.10.10 371 464 4.5E-5 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Gene3D G3DSA:2.150.10.10 791 888 1.4E-7 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Pfam PF03895 YadA-like membrane anchor domain 1773 1833 1.3E-17 T 12-10-2018 IPR005594 YadA-like, C-terminal MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 SUPERFAMILY SSF101967 675 785 1.44E-7 T 12-10-2018 MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Gene3D G3DSA:2.150.10.10 1642 1754 3.2E-8 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 Gene3D G3DSA:2.150.10.10 119 270 5.1E-21 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c07900 e6e5fe09a1d722056b6788dbe678eebf 1833 SUPERFAMILY SSF101967 893 998 9.55E-6 T 12-10-2018 MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 Pfam PF05860 haemagglutination activity domain 84 215 1.5E-31 T 12-10-2018 IPR008638 Filamentous haemagglutinin, N-terminal MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 Gene3D G3DSA:2.160.20.10 84 391 4.1E-94 T 12-10-2018 IPR012334 Pectin lyase fold MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 555 585 0.033 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 600 635 0.13 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 730 763 2.0E-5 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1129 1167 0.2 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1235 1263 0.36 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 895 931 2.1E-6 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 355 393 2.8 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 933 971 6.4E-8 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 531 565 0.12 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1032 1053 0.89 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 765 805 6.7E-4 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 332 355 0.033 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 574 591 0.88 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 637 662 0.001 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1279 1305 0.42 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 827 859 8.0E-4 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 973 1012 6.7E-6 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1047 1078 0.086 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 657 699 2.0 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 786 824 0.07 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 875 905 3.7E-4 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 SUPERFAMILY SSF51126 85 406 9.42E-53 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 Pfam PF04829 Pre-toxin domain with VENN motif 2831 2881 5.7E-16 T 12-10-2018 IPR006914 VENN motif-containing domain MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 Pfam PF13332 Haemagluttinin repeat 2328 2501 7.8E-37 T 12-10-2018 IPR025157 Hemagglutinin repeat MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 Pfam PF13332 Haemagluttinin repeat 2013 2082 0.0015 T 12-10-2018 IPR025157 Hemagglutinin repeat MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 Pfam PF13332 Haemagluttinin repeat 2085 2217 8.4E-7 T 12-10-2018 IPR025157 Hemagglutinin repeat MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 SMART SM00912 97 217 3.5E-45 T 12-10-2018 IPR008638 Filamentous haemagglutinin, N-terminal MIM_c35270 be512814563aad2161c2ec1a6914a942 3133 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 116 211 2.6E-20 T 12-10-2018 IPR008638 Filamentous haemagglutinin, N-terminal MIM_c13430 f4f68d2389fcaeea2fd2f9c67e349638 320 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c13430 f4f68d2389fcaeea2fd2f9c67e349638 320 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 222 310 2.2E-16 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c13430 f4f68d2389fcaeea2fd2f9c67e349638 320 Gene3D G3DSA:3.40.50.300 3 319 1.6E-85 T 12-10-2018 MIM_c13430 f4f68d2389fcaeea2fd2f9c67e349638 320 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 224 289 1.1E-13 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c13430 f4f68d2389fcaeea2fd2f9c67e349638 320 SMART SM00382 41 222 3.7E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c13430 f4f68d2389fcaeea2fd2f9c67e349638 320 SUPERFAMILY SSF52540 6 243 1.21E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c13430 f4f68d2389fcaeea2fd2f9c67e349638 320 Pfam PF00005 ABC transporter 32 173 1.1E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c30920 ee07a110461c7842fe12c4631dffd3f4 380 Gene3D G3DSA:1.10.287.70 164 256 1.9E-5 T 12-10-2018 MIM_c30920 ee07a110461c7842fe12c4631dffd3f4 380 SUPERFAMILY SSF81324 161 255 9.94E-7 T 12-10-2018 MIM_c30920 ee07a110461c7842fe12c4631dffd3f4 380 Gene3D G3DSA:3.40.190.10 257 341 9.9E-17 T 12-10-2018 MIM_c30920 ee07a110461c7842fe12c4631dffd3f4 380 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 52 377 3.3E-51 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c30920 ee07a110461c7842fe12c4631dffd3f4 380 SUPERFAMILY SSF53850 27 378 6.42E-50 T 12-10-2018 MIM_c30920 ee07a110461c7842fe12c4631dffd3f4 380 Gene3D G3DSA:3.40.190.10 47 163 3.7E-26 T 12-10-2018 MIM_c30920 ee07a110461c7842fe12c4631dffd3f4 380 SMART SM00062 51 379 4.7E-20 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c30920 ee07a110461c7842fe12c4631dffd3f4 380 SMART SM00079 51 378 1.7E-6 T 12-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 MIM_c30920 ee07a110461c7842fe12c4631dffd3f4 380 Pfam PF00060 Ligand-gated ion channel 167 268 4.5E-7 T 12-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 MIM_c06820 e1f4756326a6c1a53d1c1642eec7bedf 523 Pfam PF00342 Phosphoglucose isomerase 51 512 1.5E-138 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c06820 e1f4756326a6c1a53d1c1642eec7bedf 523 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 39 498 33.096 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c06820 e1f4756326a6c1a53d1c1642eec7bedf 523 PRINTS PR00662 Glucose-6-phosphate isomerase signature 439 457 2.3E-47 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c06820 e1f4756326a6c1a53d1c1642eec7bedf 523 PRINTS PR00662 Glucose-6-phosphate isomerase signature 126 145 2.3E-47 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c06820 e1f4756326a6c1a53d1c1642eec7bedf 523 PRINTS PR00662 Glucose-6-phosphate isomerase signature 471 484 2.3E-47 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c06820 e1f4756326a6c1a53d1c1642eec7bedf 523 PRINTS PR00662 Glucose-6-phosphate isomerase signature 235 253 2.3E-47 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c06820 e1f4756326a6c1a53d1c1642eec7bedf 523 PRINTS PR00662 Glucose-6-phosphate isomerase signature 457 471 2.3E-47 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c06820 e1f4756326a6c1a53d1c1642eec7bedf 523 PRINTS PR00662 Glucose-6-phosphate isomerase signature 312 333 2.3E-47 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c06820 e1f4756326a6c1a53d1c1642eec7bedf 523 Gene3D G3DSA:3.40.50.10490 91 265 6.6E-156 T 12-10-2018 MIM_c06820 e1f4756326a6c1a53d1c1642eec7bedf 523 Gene3D G3DSA:1.10.1390.10 481 522 9.8E-17 T 12-10-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c06820 e1f4756326a6c1a53d1c1642eec7bedf 523 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 239 252 - T 12-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c06820 e1f4756326a6c1a53d1c1642eec7bedf 523 Gene3D G3DSA:3.40.50.10490 40 480 6.6E-156 T 12-10-2018 MIM_c06820 e1f4756326a6c1a53d1c1642eec7bedf 523 SUPERFAMILY SSF53697 37 520 7.28E-152 T 12-10-2018 MIM_c06820 e1f4756326a6c1a53d1c1642eec7bedf 523 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 471 488 - T 12-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c40920 5c77fa7a68b059f36bb20de5e7a4bcb1 553 SMART SM00382 309 501 3.4E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c40920 5c77fa7a68b059f36bb20de5e7a4bcb1 553 SMART SM00382 33 232 2.7E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c40920 5c77fa7a68b059f36bb20de5e7a4bcb1 553 SUPERFAMILY SSF52540 276 523 1.45E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c40920 5c77fa7a68b059f36bb20de5e7a4bcb1 553 ProSitePatterns PS00211 ABC transporters family signature. 424 438 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c40920 5c77fa7a68b059f36bb20de5e7a4bcb1 553 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c40920 5c77fa7a68b059f36bb20de5e7a4bcb1 553 Pfam PF00005 ABC transporter 25 182 9.3E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c40920 5c77fa7a68b059f36bb20de5e7a4bcb1 553 Pfam PF00005 ABC transporter 300 451 1.2E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c40920 5c77fa7a68b059f36bb20de5e7a4bcb1 553 SUPERFAMILY SSF52540 5 255 1.49E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c40920 5c77fa7a68b059f36bb20de5e7a4bcb1 553 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 266 1.7E-7 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c40920 5c77fa7a68b059f36bb20de5e7a4bcb1 553 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 503 531 2.9E-5 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c40920 5c77fa7a68b059f36bb20de5e7a4bcb1 553 Gene3D G3DSA:3.40.50.300 4 273 5.6E-83 T 12-10-2018 MIM_c40920 5c77fa7a68b059f36bb20de5e7a4bcb1 553 Gene3D G3DSA:3.40.50.300 274 552 3.9E-83 T 12-10-2018 MIM_c30850 e4a51003296c9d8b157e77826ebdf2d9 250 Pfam PF09859 Oxygenase, catalysing oxidative methylation of damaged DNA 78 249 2.5E-77 T 12-10-2018 IPR018655 Protein of unknown function DUF2086 MIM_c30850 e4a51003296c9d8b157e77826ebdf2d9 250 Gene3D G3DSA:2.60.120.620 31 246 4.9E-10 T 12-10-2018 MIM_c31560 291042245db60bd4781926c264b66942 311 TIGRFAM TIGR02439 catechol_proteo: catechol 1,2-dioxygenase 7 292 3.8E-138 T 12-10-2018 IPR012801 Catechol 1,2-dioxygenase, proteobacteria GO:0005506|GO:0018576|GO:0019614|GO:0055114 KEGG: 00361+1.13.11.1|KEGG: 00362+1.13.11.1|KEGG: 00364+1.13.11.1|KEGG: 00623+1.13.11.1 MIM_c31560 291042245db60bd4781926c264b66942 311 SUPERFAMILY SSF49482 6 294 5.1E-95 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 MIM_c31560 291042245db60bd4781926c264b66942 311 Pfam PF04444 Catechol dioxygenase N terminus 27 94 1.1E-22 T 12-10-2018 IPR007535 Catechol dioxygenase, N-terminal GO:0005506|GO:0009712|GO:0018576|GO:0055114 MIM_c31560 291042245db60bd4781926c264b66942 311 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 136 164 - T 12-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 MIM_c31560 291042245db60bd4781926c264b66942 311 Gene3D G3DSA:2.60.130.10 1 311 2.5E-118 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 MIM_c31560 291042245db60bd4781926c264b66942 311 Pfam PF00775 Dioxygenase 105 293 7.5E-67 T 12-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 MIM_c19520 5720df7dcfa4aedc256efe8cccff9c8c 109 Gene3D G3DSA:3.10.50.40 1 108 3.4E-49 T 12-10-2018 MIM_c19520 5720df7dcfa4aedc256efe8cccff9c8c 109 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 15 106 1.2E-38 T 12-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain MIM_c19520 5720df7dcfa4aedc256efe8cccff9c8c 109 SUPERFAMILY SSF54534 2 108 6.48E-45 T 12-10-2018 MIM_c07970 7e99af2d6c70644c032be6ad3d4cdaaf 104 TIGRFAM TIGR03130 malonate_delta: malonate decarboxylase acyl carrier protein 2 98 1.4E-36 T 12-10-2018 IPR009662 Malonate decarboxylase delta subunit MIM_c07970 7e99af2d6c70644c032be6ad3d4cdaaf 104 ProDom PD015450 MALONATE DECARBOXYLASE SUBUNIT DELTA ACYL CARRIER DECARBOXYLASE PLASMID DIRECT SEQUENCING 1 99 2.0E-24 T 12-10-2018 IPR009662 Malonate decarboxylase delta subunit MIM_c07970 7e99af2d6c70644c032be6ad3d4cdaaf 104 Pfam PF06857 Malonate decarboxylase delta subunit (MdcD) 19 98 4.2E-26 T 12-10-2018 IPR023439 Malonate decarboxylase/citrate lyase acyl carrier protein MIM_c07970 7e99af2d6c70644c032be6ad3d4cdaaf 104 Hamap MF_00710 Malonate decarboxylase acyl carrier protein [mdcC]. 1 103 44.939 T 12-10-2018 IPR009662 Malonate decarboxylase delta subunit MIM_c39560 5ef411a09afc89564cfc79325c6e7bfb 210 Pfam PF01081 KDPG and KHG aldolase 7 182 3.9E-24 T 12-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MIM_c39560 5ef411a09afc89564cfc79325c6e7bfb 210 SUPERFAMILY SSF51569 5 204 8.79E-51 T 12-10-2018 MIM_c39560 5ef411a09afc89564cfc79325c6e7bfb 210 Gene3D G3DSA:3.20.20.70 3 210 5.2E-57 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c39560 5ef411a09afc89564cfc79325c6e7bfb 210 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 123 136 - T 12-10-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MIM_c00750 40e9d252ed759f1b412211425c8aab0e 219 Pfam PF00813 FliP family 14 212 1.4E-62 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MIM_c00750 40e9d252ed759f1b412211425c8aab0e 219 TIGRFAM TIGR01102 yscR: type III secretion apparatus protein, YscR/HrcR family 12 212 1.0E-78 T 12-10-2018 IPR005773 Yop virulence translocation protein R GO:0015031|GO:0016021 MIM_c00750 40e9d252ed759f1b412211425c8aab0e 219 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 193 205 - T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MIM_c00750 40e9d252ed759f1b412211425c8aab0e 219 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 145 165 4.4E-64 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MIM_c00750 40e9d252ed759f1b412211425c8aab0e 219 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 31 51 4.4E-64 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MIM_c00750 40e9d252ed759f1b412211425c8aab0e 219 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 51 70 4.4E-64 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MIM_c00750 40e9d252ed759f1b412211425c8aab0e 219 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 166 187 4.4E-64 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MIM_c00750 40e9d252ed759f1b412211425c8aab0e 219 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 12 31 4.4E-64 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MIM_c00750 40e9d252ed759f1b412211425c8aab0e 219 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 190 215 4.4E-64 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MIM_c26200 8e1e12f629ceab6c9e9b877527214de5 105 Pfam PF07843 Protein of unknown function (DUF1634) 18 101 1.4E-8 T 12-10-2018 IPR012861 Protein of unknown function DUF1634 MIM_c33830 ecd329023a1d658766ec7a61d5b81abd 191 Pfam PF06684 Amino acid synthesis 5 177 1.2E-65 T 12-10-2018 IPR009569 Amino acid synthesis, putative MIM_c33830 ecd329023a1d658766ec7a61d5b81abd 191 SUPERFAMILY SSF160519 1 191 7.85E-65 T 12-10-2018 IPR035936 BB2672 superfamily MIM_c33830 ecd329023a1d658766ec7a61d5b81abd 191 Gene3D G3DSA:3.30.1330.110 1 191 7.3E-73 T 12-10-2018 IPR035936 BB2672 superfamily MIM_c37040 98d1fad887e73384ee81e9a3b2070406 275 Gene3D G3DSA:1.10.8.10 3 81 1.8E-19 T 12-10-2018 MIM_c37040 98d1fad887e73384ee81e9a3b2070406 275 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 178 184 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MIM_c37040 98d1fad887e73384ee81e9a3b2070406 275 Pfam PF05175 Methyltransferase small domain 101 189 3.3E-19 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 MIM_c37040 98d1fad887e73384ee81e9a3b2070406 275 Gene3D G3DSA:3.40.50.150 84 272 1.1E-59 T 12-10-2018 MIM_c37040 98d1fad887e73384ee81e9a3b2070406 275 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 21 268 1.1E-89 T 12-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 MIM_c37040 98d1fad887e73384ee81e9a3b2070406 275 SUPERFAMILY SSF53335 18 268 1.33E-59 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c37040 98d1fad887e73384ee81e9a3b2070406 275 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 18 268 4.7E-72 T 12-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 MIM_c37040 98d1fad887e73384ee81e9a3b2070406 275 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 1 273 41.456 T 12-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 MIM_c17440 262cea27badea2a7a6782b93bbbfeb2f 311 SMART SM01130 11 307 1.4E-53 T 12-10-2018 IPR002220 DapA-like GO:0016829 MIM_c17440 262cea27badea2a7a6782b93bbbfeb2f 311 Pfam PF00701 Dihydrodipicolinate synthetase family 12 304 7.8E-34 T 12-10-2018 IPR002220 DapA-like GO:0016829 MIM_c17440 262cea27badea2a7a6782b93bbbfeb2f 311 SUPERFAMILY SSF51569 10 307 4.5E-60 T 12-10-2018 MIM_c17440 262cea27badea2a7a6782b93bbbfeb2f 311 PIRSF PIRSF001365 7 310 3.2E-49 T 12-10-2018 IPR002220 DapA-like GO:0016829 MIM_c17440 262cea27badea2a7a6782b93bbbfeb2f 311 Gene3D G3DSA:3.20.20.70 7 309 4.1E-93 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c39750 dfd88920fb9a16719d6eb0f852d5c191 151 SUPERFAMILY SSF102546 1 141 2.09E-38 T 12-10-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 MIM_c39750 dfd88920fb9a16719d6eb0f852d5c191 151 Gene3D G3DSA:3.40.1650.10 1 144 2.8E-47 T 12-10-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 MIM_c39750 dfd88920fb9a16719d6eb0f852d5c191 151 Pfam PF05025 RbsD / FucU transport protein family 3 140 7.3E-32 T 12-10-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 MIM_c03220 682a8cc4e96b1393ae8f7dd1c4688bc0 914 Pfam PF14351 Domain of unknown function (DUF4401) 376 705 1.0E-16 T 12-10-2018 IPR025513 Domain of unknown function DUF4401 MIM_c03220 682a8cc4e96b1393ae8f7dd1c4688bc0 914 Pfam PF14345 GDYXXLXY protein 766 906 1.6E-31 T 12-10-2018 IPR025833 GDYXXLXY protein MIM_c03220 682a8cc4e96b1393ae8f7dd1c4688bc0 914 Pfam PF09925 Predicted membrane protein (DUF2157) 23 151 4.9E-21 T 12-10-2018 IPR018677 Domain of unknown function DUF2157 MIM_c20970 498cdb65e852c364fb7fe5a786b2e8f6 539 SUPERFAMILY SSF51905 3 536 3.72E-85 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c20970 498cdb65e852c364fb7fe5a786b2e8f6 539 Gene3D G3DSA:4.10.450.10 36 195 1.2E-161 T 12-10-2018 IPR027424 Glucose Oxidase, domain 2 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 MIM_c20970 498cdb65e852c364fb7fe5a786b2e8f6 539 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 255 269 - T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c20970 498cdb65e852c364fb7fe5a786b2e8f6 539 Gene3D G3DSA:1.10.1220.110 95 149 1.2E-161 T 12-10-2018 MIM_c20970 498cdb65e852c364fb7fe5a786b2e8f6 539 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 80 103 - T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c20970 498cdb65e852c364fb7fe5a786b2e8f6 539 PIRSF PIRSF000137 1 539 2.3E-138 T 12-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c20970 498cdb65e852c364fb7fe5a786b2e8f6 539 SUPERFAMILY SSF54373 291 475 3.14E-41 T 12-10-2018 MIM_c20970 498cdb65e852c364fb7fe5a786b2e8f6 539 Pfam PF05199 GMC oxidoreductase 389 527 4.0E-39 T 12-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 MIM_c20970 498cdb65e852c364fb7fe5a786b2e8f6 539 Gene3D G3DSA:3.30.410.40 150 472 1.2E-161 T 12-10-2018 MIM_c20970 498cdb65e852c364fb7fe5a786b2e8f6 539 Gene3D G3DSA:3.50.50.60 4 531 1.2E-161 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c20970 498cdb65e852c364fb7fe5a786b2e8f6 539 Pfam PF00732 GMC oxidoreductase 4 296 9.4E-75 T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c29840 cdf025d5529e5f914b11fac72de22172 371 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 17 366 8.5E-118 T 12-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 MIM_c29840 cdf025d5529e5f914b11fac72de22172 371 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 176 287 8.3E-13 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MIM_c29840 cdf025d5529e5f914b11fac72de22172 371 Gene3D G3DSA:3.10.180.10 171 367 3.4E-68 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c29840 cdf025d5529e5f914b11fac72de22172 371 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 9 154 1.7E-64 T 12-10-2018 MIM_c29840 cdf025d5529e5f914b11fac72de22172 371 Gene3D G3DSA:3.10.180.10 7 166 9.4E-53 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c29840 cdf025d5529e5f914b11fac72de22172 371 PIRSF PIRSF009283 1 368 7.8E-122 T 12-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 MIM_c29840 cdf025d5529e5f914b11fac72de22172 371 SUPERFAMILY SSF54593 7 354 1.07E-80 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c02980 538a535c9fe8605defa20070e2cf873f 259 Gene3D G3DSA:3.20.20.370 62 257 7.0E-53 T 12-10-2018 MIM_c02980 538a535c9fe8605defa20070e2cf873f 259 Pfam PF01522 Polysaccharide deacetylase 70 186 1.7E-28 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MIM_c02980 538a535c9fe8605defa20070e2cf873f 259 SUPERFAMILY SSF88713 71 252 1.29E-50 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MIM_c12300 1d800ff858bd59d3d02bfe018085db99 395 SMART SM00558 101 223 0.0018 T 12-10-2018 IPR003347 JmjC domain MIM_c12300 1d800ff858bd59d3d02bfe018085db99 395 SUPERFAMILY SSF51197 10 318 1.0E-66 T 12-10-2018 MIM_c12300 1d800ff858bd59d3d02bfe018085db99 395 Pfam PF08007 Cupin superfamily protein 18 327 7.2E-85 T 12-10-2018 IPR003347 JmjC domain MIM_c12300 1d800ff858bd59d3d02bfe018085db99 395 Gene3D G3DSA:1.10.10.2510 250 395 4.2E-15 T 12-10-2018 MIM_c12300 1d800ff858bd59d3d02bfe018085db99 395 Gene3D G3DSA:2.60.120.650 2 213 1.8E-77 T 12-10-2018 MIM_c24880 7d0a0a5fd363fa414f7947934a298bfa 373 Pfam PF01070 FMN-dependent dehydrogenase 29 371 9.4E-124 T 12-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 MIM_c24880 7d0a0a5fd363fa414f7947934a298bfa 373 PIRSF PIRSF000138 2 373 1.3E-121 T 12-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 MIM_c24880 7d0a0a5fd363fa414f7947934a298bfa 373 Gene3D G3DSA:3.20.20.70 17 373 2.6E-130 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c24880 7d0a0a5fd363fa414f7947934a298bfa 373 SUPERFAMILY SSF51395 18 370 5.8E-93 T 12-10-2018 MIM_c03290 fac9f6d89332e836c85e2d59df7aab29 393 PIRSF PIRSF000429 1 393 1.4E-114 T 12-10-2018 IPR002155 Thiolase GO:0016747 MIM_c03290 fac9f6d89332e836c85e2d59df7aab29 393 Gene3D G3DSA:3.40.47.10 127 389 9.1E-142 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c03290 fac9f6d89332e836c85e2d59df7aab29 393 Gene3D G3DSA:3.40.47.10 7 276 9.1E-142 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c03290 fac9f6d89332e836c85e2d59df7aab29 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 391 1.4E-128 T 12-10-2018 IPR002155 Thiolase GO:0016747 MIM_c03290 fac9f6d89332e836c85e2d59df7aab29 393 SUPERFAMILY SSF53901 5 269 1.06E-77 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c03290 fac9f6d89332e836c85e2d59df7aab29 393 Pfam PF02803 Thiolase, C-terminal domain 271 391 2.0E-41 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 MIM_c03290 fac9f6d89332e836c85e2d59df7aab29 393 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 MIM_c03290 fac9f6d89332e836c85e2d59df7aab29 393 Pfam PF00108 Thiolase, N-terminal domain 5 263 1.9E-88 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 MIM_c03290 fac9f6d89332e836c85e2d59df7aab29 393 SUPERFAMILY SSF53901 271 392 9.92E-40 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c36990 0641c43d2254f1b3a7e66eb323cc19cf 120 TIGRFAM TIGR00526 folB_dom: FolB domain 5 118 3.0E-15 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MIM_c36990 0641c43d2254f1b3a7e66eb323cc19cf 120 Gene3D G3DSA:3.30.1130.10 1 120 6.1E-33 T 12-10-2018 MIM_c36990 0641c43d2254f1b3a7e66eb323cc19cf 120 Pfam PF02152 Dihydroneopterin aldolase 6 116 5.5E-23 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MIM_c36990 0641c43d2254f1b3a7e66eb323cc19cf 120 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 5 116 5.9E-21 T 12-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MIM_c36990 0641c43d2254f1b3a7e66eb323cc19cf 120 SUPERFAMILY SSF55620 3 119 7.23E-25 T 12-10-2018 MIM_c36990 0641c43d2254f1b3a7e66eb323cc19cf 120 SMART SM00905 6 117 9.7E-23 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MIM_c01720 38330aa58712bebc72d1b3f00d473918 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 326 2.2E-80 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c01720 38330aa58712bebc72d1b3f00d473918 330 Gene3D G3DSA:3.40.190.10 132 255 3.0E-106 T 12-10-2018 MIM_c01720 38330aa58712bebc72d1b3f00d473918 330 PIRSF PIRSF017082 1 330 2.2E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c01720 38330aa58712bebc72d1b3f00d473918 330 SUPERFAMILY SSF53850 120 290 3.33E-10 T 12-10-2018 MIM_c01720 38330aa58712bebc72d1b3f00d473918 330 Gene3D G3DSA:3.40.190.150 34 319 3.0E-106 T 12-10-2018 MIM_c25860 51a00706389a729d811c5f23fbbc8e45 447 Gene3D G3DSA:3.50.50.60 9 430 2.0E-106 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c25860 51a00706389a729d811c5f23fbbc8e45 447 SUPERFAMILY SSF51905 17 280 1.04E-17 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c25860 51a00706389a729d811c5f23fbbc8e45 447 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 16 349 8.1E-110 T 12-10-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase MIM_c13940 c7906f8d731293087c873c05b152b49a 236 Pfam PF00005 ABC transporter 19 164 1.8E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c13940 c7906f8d731293087c873c05b152b49a 236 SMART SM00382 28 215 2.0E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c13940 c7906f8d731293087c873c05b152b49a 236 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c13940 c7906f8d731293087c873c05b152b49a 236 Gene3D G3DSA:3.40.50.300 1 236 2.1E-62 T 12-10-2018 MIM_c13940 c7906f8d731293087c873c05b152b49a 236 SUPERFAMILY SSF52540 3 233 1.25E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c08880 a6ed1d6c2ed4d2fd5190965da31baea9 424 PIRSF PIRSF000018 18 424 1.5E-113 T 12-10-2018 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 MIM_c08880 a6ed1d6c2ed4d2fd5190965da31baea9 424 Gene3D G3DSA:1.10.760.10 304 424 1.4E-30 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c08880 a6ed1d6c2ed4d2fd5190965da31baea9 424 Pfam PF00034 Cytochrome c 47 147 1.8E-5 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c08880 a6ed1d6c2ed4d2fd5190965da31baea9 424 Pfam PF00034 Cytochrome c 195 299 1.3E-5 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c08880 a6ed1d6c2ed4d2fd5190965da31baea9 424 SUPERFAMILY SSF46626 184 301 1.83E-14 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c08880 a6ed1d6c2ed4d2fd5190965da31baea9 424 SUPERFAMILY SSF46626 318 412 1.1E-23 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c08880 a6ed1d6c2ed4d2fd5190965da31baea9 424 Gene3D G3DSA:1.10.760.10 163 303 4.2E-8 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c08880 a6ed1d6c2ed4d2fd5190965da31baea9 424 Gene3D G3DSA:1.10.760.10 2 158 6.2E-12 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c08880 a6ed1d6c2ed4d2fd5190965da31baea9 424 SUPERFAMILY SSF46626 35 170 4.83E-24 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c08880 a6ed1d6c2ed4d2fd5190965da31baea9 424 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 317 401 1.0E-10 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c40500 34792b677e9bd29d87c479984b227ca1 408 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site MIM_c40500 34792b677e9bd29d87c479984b227ca1 408 SUPERFAMILY SSF53901 215 406 1.48E-59 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c40500 34792b677e9bd29d87c479984b227ca1 408 Gene3D G3DSA:3.40.47.10 5 259 4.5E-57 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c40500 34792b677e9bd29d87c479984b227ca1 408 SMART SM00825 Beta-ketoacyl synthase 4 407 3.3E-9 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MIM_c40500 34792b677e9bd29d87c479984b227ca1 408 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 246 9.8E-45 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MIM_c40500 34792b677e9bd29d87c479984b227ca1 408 SUPERFAMILY SSF53901 1 250 1.96E-54 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c40500 34792b677e9bd29d87c479984b227ca1 408 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 363 5.8E-31 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MIM_c40500 34792b677e9bd29d87c479984b227ca1 408 Gene3D G3DSA:3.40.47.10 260 408 3.9E-46 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c33590 eaacf505aa8d23cf83df3a1a1125ebfa 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 2.8E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c33590 eaacf505aa8d23cf83df3a1a1125ebfa 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 2.8E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c33590 eaacf505aa8d23cf83df3a1a1125ebfa 218 SUPERFAMILY SSF48498 72 208 4.34E-29 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MIM_c33590 eaacf505aa8d23cf83df3a1a1125ebfa 218 Gene3D G3DSA:1.10.10.60 6 56 5.0E-24 T 12-10-2018 MIM_c33590 eaacf505aa8d23cf83df3a1a1125ebfa 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 55 3.1E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c33590 eaacf505aa8d23cf83df3a1a1125ebfa 218 SUPERFAMILY SSF46689 5 69 1.8E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c33590 eaacf505aa8d23cf83df3a1a1125ebfa 218 ProSitePatterns PS01081 TetR-type HTH domain signature. 23 54 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MIM_c33590 eaacf505aa8d23cf83df3a1a1125ebfa 218 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 73 204 6.0E-26 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 MIM_c33590 eaacf505aa8d23cf83df3a1a1125ebfa 218 Gene3D G3DSA:1.10.357.10 57 208 9.3E-34 T 12-10-2018 MIM_c33590 eaacf505aa8d23cf83df3a1a1125ebfa 218 PRINTS PR00400 Tetracycline repressor protein signature 131 150 8.7E-23 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 MIM_c33590 eaacf505aa8d23cf83df3a1a1125ebfa 218 PRINTS PR00400 Tetracycline repressor protein signature 23 46 8.7E-23 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 MIM_c33590 eaacf505aa8d23cf83df3a1a1125ebfa 218 PRINTS PR00400 Tetracycline repressor protein signature 95 118 8.7E-23 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 MIM_c33590 eaacf505aa8d23cf83df3a1a1125ebfa 218 PRINTS PR00400 Tetracycline repressor protein signature 191 205 8.7E-23 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 MIM_c33590 eaacf505aa8d23cf83df3a1a1125ebfa 218 PRINTS PR00400 Tetracycline repressor protein signature 75 94 8.7E-23 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 MIM_24p00170 3628901384e274d19bd13e7d785ea4e9 729 Gene3D G3DSA:1.10.443.10 511 728 2.1E-28 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MIM_24p00170 3628901384e274d19bd13e7d785ea4e9 729 SUPERFAMILY SSF56349 360 724 3.83E-33 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MIM_24p00170 3628901384e274d19bd13e7d785ea4e9 729 Pfam PF00589 Phage integrase family 532 713 1.5E-18 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MIM_24p00170 3628901384e274d19bd13e7d785ea4e9 729 Pfam PF12482 Phage integrase protein 205 291 2.1E-18 T 12-10-2018 IPR022169 Protein of unknown function DUF3701 MIM_c27010 1c54bac5fc6d80fbc9aa96010b1266fa 248 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 15 185 1.3E-31 T 12-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain MIM_c27010 1c54bac5fc6d80fbc9aa96010b1266fa 248 SUPERFAMILY SSF52540 11 210 1.2E-31 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c27010 1c54bac5fc6d80fbc9aa96010b1266fa 248 Hamap MF_01389 Urease accessory protein UreG [ureG]. 11 211 39.414 T 12-10-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 MIM_c27010 1c54bac5fc6d80fbc9aa96010b1266fa 248 PIRSF PIRSF005624 2 216 3.4E-43 T 12-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 MIM_c27010 1c54bac5fc6d80fbc9aa96010b1266fa 248 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 13 205 3.3E-71 T 12-10-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 MIM_c27010 1c54bac5fc6d80fbc9aa96010b1266fa 248 Gene3D G3DSA:3.40.50.300 12 208 4.5E-43 T 12-10-2018 MIM_c24770 03fbe557c452d9034f4e050a003d8d11 62 SMART SM00530 4 59 5.1E-18 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c24770 03fbe557c452d9034f4e050a003d8d11 62 Pfam PF01381 Helix-turn-helix 5 59 1.5E-17 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c24770 03fbe557c452d9034f4e050a003d8d11 62 SUPERFAMILY SSF47413 2 61 8.04E-19 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c24770 03fbe557c452d9034f4e050a003d8d11 62 Gene3D G3DSA:1.10.260.40 1 62 3.1E-27 T 12-10-2018 MIM_c26510 dc33de800264614810cba62549dd233b 244 SMART SM00882 9 202 9.3E-8 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MIM_c26510 dc33de800264614810cba62549dd233b 244 Pfam PF01144 Coenzyme A transferase 15 201 1.5E-17 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MIM_c26510 dc33de800264614810cba62549dd233b 244 SUPERFAMILY SSF100950 4 233 2.65E-50 T 12-10-2018 IPR037171 NagB/RpiA transferase-like MIM_c26510 dc33de800264614810cba62549dd233b 244 Gene3D G3DSA:3.40.1080.10 3 237 4.8E-55 T 12-10-2018 MIM_c26810 c130ec96fe3cb038535711730a189656 94 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 83 6.3E-27 T 12-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 MIM_c26810 c130ec96fe3cb038535711730a189656 94 Gene3D G3DSA:3.30.1070.10 1 84 7.5E-26 T 12-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 MIM_c26810 c130ec96fe3cb038535711730a189656 94 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 88 18.716 T 12-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 MIM_c26810 c130ec96fe3cb038535711730a189656 94 SUPERFAMILY SSF55229 36 85 3.14E-14 T 12-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 MIM_c26810 c130ec96fe3cb038535711730a189656 94 Pfam PF03776 Septum formation topological specificity factor MinE 14 83 3.1E-24 T 12-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 MIM_c02420 8f48c0a05007a0eb45f6e54eea29b626 263 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 169 187 - T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MIM_c02420 8f48c0a05007a0eb45f6e54eea29b626 263 Hamap MF_01974 Methionine aminopeptidase [map]. 5 252 40.822 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MIM_c02420 8f48c0a05007a0eb45f6e54eea29b626 263 Gene3D G3DSA:3.90.230.10 3 258 7.9E-107 T 12-10-2018 MIM_c02420 8f48c0a05007a0eb45f6e54eea29b626 263 SUPERFAMILY SSF55920 6 257 6.28E-93 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like MIM_c02420 8f48c0a05007a0eb45f6e54eea29b626 263 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 6 250 3.8E-94 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MIM_c02420 8f48c0a05007a0eb45f6e54eea29b626 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 194 206 2.4E-22 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MIM_c02420 8f48c0a05007a0eb45f6e54eea29b626 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 71 84 2.4E-22 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MIM_c02420 8f48c0a05007a0eb45f6e54eea29b626 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 163 175 2.4E-22 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MIM_c02420 8f48c0a05007a0eb45f6e54eea29b626 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 93 109 2.4E-22 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MIM_c02420 8f48c0a05007a0eb45f6e54eea29b626 263 Pfam PF00557 Metallopeptidase family M24 15 243 1.6E-53 T 12-10-2018 IPR000994 Peptidase M24 MIM_c09020 a03b5f78b4c4c24166a94cd37f4de2ed 506 Pfam PF01425 Amidase 25 485 3.3E-140 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MIM_c09020 a03b5f78b4c4c24166a94cd37f4de2ed 506 SUPERFAMILY SSF75304 3 502 6.54E-151 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MIM_c09020 a03b5f78b4c4c24166a94cd37f4de2ed 506 ProSitePatterns PS00571 Amidases signature. 151 182 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 MIM_c09020 a03b5f78b4c4c24166a94cd37f4de2ed 506 Gene3D G3DSA:3.90.1300.10 4 505 1.1E-184 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MIM_c09020 a03b5f78b4c4c24166a94cd37f4de2ed 506 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 12 496 87.807 T 12-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MIM_c09020 a03b5f78b4c4c24166a94cd37f4de2ed 506 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 13 496 5.8E-162 T 12-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MIM_c22160 5928d65a48b8915e3a9258131b9ccd77 229 Pfam PF01730 UreF 37 183 7.1E-40 T 12-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 MIM_c22160 5928d65a48b8915e3a9258131b9ccd77 229 PIRSF PIRSF009467 2 229 4.5E-59 T 12-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 MIM_c22160 5928d65a48b8915e3a9258131b9ccd77 229 Gene3D G3DSA:1.10.4190.10 3 202 1.0E-54 T 12-10-2018 IPR038277 UreF domain superfamily MIM_c22160 5928d65a48b8915e3a9258131b9ccd77 229 Hamap MF_01385 Urease accessory protein UreF [ureF]. 5 229 29.259 T 12-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 MIM_c08640 4926e6370b76ea8dc9287acf42538add 112 SUPERFAMILY SSF54292 20 99 4.98E-19 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MIM_c08640 4926e6370b76ea8dc9287acf42538add 112 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 18 98 3.7E-28 T 12-10-2018 MIM_c08640 4926e6370b76ea8dc9287acf42538add 112 Gene3D G3DSA:3.10.20.440 4 105 1.2E-20 T 12-10-2018 MIM_c02060 1d7db5ae227ffe619235a665a6dba70f 211 Gene3D G3DSA:3.40.50.850 3 208 6.8E-57 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MIM_c02060 1d7db5ae227ffe619235a665a6dba70f 211 Pfam PF00857 Isochorismatase family 25 198 4.7E-39 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 MIM_c02060 1d7db5ae227ffe619235a665a6dba70f 211 SUPERFAMILY SSF52499 24 204 7.85E-50 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MIM_c33440 382362e8b1eafacbf5bd58e83aafe1d5 302 PIRSF PIRSF001439 2 302 4.5E-67 T 12-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 MIM_c33440 382362e8b1eafacbf5bd58e83aafe1d5 302 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 9 299 1.7E-47 T 12-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 MIM_c33440 382362e8b1eafacbf5bd58e83aafe1d5 302 SUPERFAMILY SSF51735 3 301 8.59E-66 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c33440 382362e8b1eafacbf5bd58e83aafe1d5 302 Gene3D G3DSA:3.40.50.720 115 284 1.7E-92 T 12-10-2018 MIM_c33440 382362e8b1eafacbf5bd58e83aafe1d5 302 Gene3D G3DSA:3.30.1780.10 15 298 1.7E-92 T 12-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 MIM_c27730 a1bfa57e7c9b7d32d3b2cfe2dccb3417 354 Gene3D G3DSA:3.20.20.70 1 354 4.0E-149 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c27730 a1bfa57e7c9b7d32d3b2cfe2dccb3417 354 TIGRFAM TIGR01521 FruBisAldo_II_B: fructose-bisphosphate aldolase, class II, Calvin cycle subtype 3 349 2.9E-186 T 12-10-2018 IPR006412 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 MIM_c27730 a1bfa57e7c9b7d32d3b2cfe2dccb3417 354 SUPERFAMILY SSF51569 1 328 1.47E-107 T 12-10-2018 MIM_c27730 a1bfa57e7c9b7d32d3b2cfe2dccb3417 354 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 329 2.1E-99 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MIM_c27730 a1bfa57e7c9b7d32d3b2cfe2dccb3417 354 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 139 150 - T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MIM_c27730 a1bfa57e7c9b7d32d3b2cfe2dccb3417 354 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 73 85 - T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MIM_c27730 a1bfa57e7c9b7d32d3b2cfe2dccb3417 354 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 327 2.2E-95 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MIM_c27730 a1bfa57e7c9b7d32d3b2cfe2dccb3417 354 PIRSF PIRSF001359 1 329 1.6E-85 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MIM_c33130 e8076a06f0cb1e21c3bfd90ed04f2bd9 144 Gene3D G3DSA:3.10.350.10 94 142 6.3E-15 T 12-10-2018 IPR036779 LysM domain superfamily MIM_c33130 e8076a06f0cb1e21c3bfd90ed04f2bd9 144 Pfam PF04972 BON domain 26 85 4.1E-10 T 12-10-2018 IPR007055 BON domain MIM_c33130 e8076a06f0cb1e21c3bfd90ed04f2bd9 144 SUPERFAMILY SSF54106 93 143 4.71E-8 T 12-10-2018 MIM_c33130 e8076a06f0cb1e21c3bfd90ed04f2bd9 144 SMART SM00257 94 143 8.2E-13 T 12-10-2018 IPR018392 LysM domain MIM_c33130 e8076a06f0cb1e21c3bfd90ed04f2bd9 144 Pfam PF01476 LysM domain 95 143 8.6E-14 T 12-10-2018 IPR018392 LysM domain MIM_c05270 84f0c35ea0e7c24b4a54c95acad22ecc 172 SUPERFAMILY SSF55154 3 167 1.8E-34 T 12-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 MIM_c05270 84f0c35ea0e7c24b4a54c95acad22ecc 172 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 22 143 0.001 T 12-10-2018 MIM_c05270 84f0c35ea0e7c24b4a54c95acad22ecc 172 Pfam PF01928 CYTH domain 3 163 5.5E-14 T 12-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 MIM_c05270 84f0c35ea0e7c24b4a54c95acad22ecc 172 Gene3D G3DSA:2.40.320.10 1 171 9.2E-32 T 12-10-2018 MIM_c05270 84f0c35ea0e7c24b4a54c95acad22ecc 172 SMART SM01118 2 169 6.5E-15 T 12-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 MIM_c27400 0d8dc6624914cdedad30acf78ec9db74 253 SUPERFAMILY SSF51621 4 248 1.35E-79 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MIM_c27400 0d8dc6624914cdedad30acf78ec9db74 253 Gene3D G3DSA:3.20.20.60 1 253 1.0E-82 T 12-10-2018 MIM_c27400 0d8dc6624914cdedad30acf78ec9db74 253 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 20 244 6.6E-52 T 12-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 MIM_c04870 18dd359b897a4f3e23c19bf97bfa2b4d 227 Gene3D G3DSA:3.40.50.880 2 227 4.1E-71 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c04870 18dd359b897a4f3e23c19bf97bfa2b4d 227 PIRSF PIRSF000495 3 227 3.9E-62 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MIM_c04870 18dd359b897a4f3e23c19bf97bfa2b4d 227 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 4 225 34.038 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MIM_c04870 18dd359b897a4f3e23c19bf97bfa2b4d 227 Pfam PF00117 Glutamine amidotransferase class-I 7 213 1.9E-18 T 12-10-2018 IPR017926 Glutamine amidotransferase MIM_c04870 18dd359b897a4f3e23c19bf97bfa2b4d 227 SUPERFAMILY SSF52317 4 225 9.73E-54 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c04870 18dd359b897a4f3e23c19bf97bfa2b4d 227 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 5 224 1.1E-58 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MIM_c26420 c7fc187c96e3328798e5f3cefe38659a 532 Gene3D G3DSA:3.40.190.10 207 520 2.9E-165 T 12-10-2018 MIM_c26420 c7fc187c96e3328798e5f3cefe38659a 532 Gene3D G3DSA:3.90.76.10 46 206 2.9E-165 T 12-10-2018 MIM_c26420 c7fc187c96e3328798e5f3cefe38659a 532 SUPERFAMILY SSF53850 25 531 1.76E-150 T 12-10-2018 MIM_c26420 c7fc187c96e3328798e5f3cefe38659a 532 Gene3D G3DSA:3.10.105.10 290 507 2.9E-165 T 12-10-2018 MIM_c26420 c7fc187c96e3328798e5f3cefe38659a 532 PIRSF PIRSF002741 8 530 4.0E-114 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MIM_c26420 c7fc187c96e3328798e5f3cefe38659a 532 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 69 451 1.6E-100 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain MIM_c12680 9588c1d204dd16071bf8b0a6c969fe3f 520 SUPERFAMILY SSF55961 162 431 2.2E-25 T 12-10-2018 MIM_c12680 9588c1d204dd16071bf8b0a6c969fe3f 520 Pfam PF00355 Rieske [2Fe-2S] domain 59 138 4.9E-13 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MIM_c12680 9588c1d204dd16071bf8b0a6c969fe3f 520 Gene3D G3DSA:2.102.10.10 54 189 5.4E-32 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MIM_c12680 9588c1d204dd16071bf8b0a6c969fe3f 520 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 99 121 - T 12-10-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0051537|GO:0055114 MIM_c12680 9588c1d204dd16071bf8b0a6c969fe3f 520 SUPERFAMILY SSF50022 50 171 5.11E-31 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MIM_c17030 b97a8430e4925e4dae7f50712bc9ea80 301 Pfam PF03466 LysR substrate binding domain 92 297 1.4E-38 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c17030 b97a8430e4925e4dae7f50712bc9ea80 301 Gene3D G3DSA:3.40.190.290 96 300 5.1E-39 T 12-10-2018 MIM_c17030 b97a8430e4925e4dae7f50712bc9ea80 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 66 1.1E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c17030 b97a8430e4925e4dae7f50712bc9ea80 301 SUPERFAMILY SSF53850 93 299 2.17E-41 T 12-10-2018 MIM_c17030 b97a8430e4925e4dae7f50712bc9ea80 301 SUPERFAMILY SSF46785 5 115 1.63E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c17030 b97a8430e4925e4dae7f50712bc9ea80 301 Gene3D G3DSA:1.10.10.10 7 95 1.5E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c16330 64487e55b871290334cf67b2b494cd46 557 Gene3D G3DSA:1.20.140.10 285 442 4.6E-39 T 12-10-2018 MIM_c16330 64487e55b871290334cf67b2b494cd46 557 SUPERFAMILY SSF47203 284 442 3.7E-40 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c16330 64487e55b871290334cf67b2b494cd46 557 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 284 440 9.5E-35 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MIM_c16330 64487e55b871290334cf67b2b494cd46 557 SUPERFAMILY SSF56645 43 293 1.01E-39 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c16330 64487e55b871290334cf67b2b494cd46 557 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 175 273 1.1E-15 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MIM_c16330 64487e55b871290334cf67b2b494cd46 557 Gene3D G3DSA:2.40.110.20 132 284 7.0E-46 T 12-10-2018 MIM_c16330 64487e55b871290334cf67b2b494cd46 557 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 399 418 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MIM_c00580 ba7c5ea06afadf19dad7f1aa279c062d 273 Gene3D G3DSA:1.10.3720.10 3 260 1.7E-54 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c00580 ba7c5ea06afadf19dad7f1aa279c062d 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 261 2.7E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c00580 ba7c5ea06afadf19dad7f1aa279c062d 273 SUPERFAMILY SSF161098 5 273 8.76E-63 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c22810 9d1683e50b95618e2539ec891d28e97e 445 ProSitePatterns PS00885 EPSP synthase signature 2. 349 367 - T 12-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MIM_c22810 9d1683e50b95618e2539ec891d28e97e 445 ProSitePatterns PS00104 EPSP synthase signature 1. 89 103 - T 12-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MIM_c22810 9d1683e50b95618e2539ec891d28e97e 445 Gene3D G3DSA:3.65.10.10 246 431 1.5E-127 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 MIM_c22810 9d1683e50b95618e2539ec891d28e97e 445 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 12 439 31.858 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MIM_c22810 9d1683e50b95618e2539ec891d28e97e 445 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 11 431 3.5E-117 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MIM_c22810 9d1683e50b95618e2539ec891d28e97e 445 PIRSF PIRSF000505 3 443 6.0E-129 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MIM_c22810 9d1683e50b95618e2539ec891d28e97e 445 SUPERFAMILY SSF55205 10 436 5.33E-112 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 MIM_c22810 9d1683e50b95618e2539ec891d28e97e 445 Gene3D G3DSA:3.65.10.10 22 228 1.5E-127 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 MIM_c22810 9d1683e50b95618e2539ec891d28e97e 445 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 16 437 3.3E-130 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MIM_c39280 29b7973251ac4b87a373881bf9085c90 327 PIRSF PIRSF017082 1 326 1.0E-82 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c39280 29b7973251ac4b87a373881bf9085c90 327 SUPERFAMILY SSF53850 114 291 5.65E-6 T 12-10-2018 MIM_c39280 29b7973251ac4b87a373881bf9085c90 327 Gene3D G3DSA:3.40.190.10 129 252 1.1E-111 T 12-10-2018 MIM_c39280 29b7973251ac4b87a373881bf9085c90 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 323 6.4E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c39280 29b7973251ac4b87a373881bf9085c90 327 Gene3D G3DSA:3.40.190.150 29 311 1.1E-111 T 12-10-2018 MIM_c01540 4eeca3f320778ba1bd046669955eb3ad 369 SUPERFAMILY SSF51679 5 359 9.13E-83 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MIM_c01540 4eeca3f320778ba1bd046669955eb3ad 369 Gene3D G3DSA:3.20.20.30 1 366 1.5E-124 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MIM_c01540 4eeca3f320778ba1bd046669955eb3ad 369 Pfam PF00296 Luciferase-like monooxygenase 16 333 1.6E-78 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MIM_c07440 dc4688b8de2046305aff9fd7f051f4fe 259 SUPERFAMILY SSF52096 2 258 4.98E-84 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c07440 dc4688b8de2046305aff9fd7f051f4fe 259 Gene3D G3DSA:1.10.12.10 202 258 4.0E-25 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MIM_c07440 dc4688b8de2046305aff9fd7f051f4fe 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 257 3.2E-75 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c07440 dc4688b8de2046305aff9fd7f051f4fe 259 Gene3D G3DSA:3.90.226.10 3 200 3.3E-70 T 12-10-2018 MIM_c17960 ecb3ac646802b3691e733a852c771576 441 Pfam PF12221 Bacterial membrane protein N terminal 7 59 6.4E-10 T 12-10-2018 IPR020980 Menbrane protein HflK, N-terminal MIM_c17960 ecb3ac646802b3691e733a852c771576 441 Pfam PF01145 SPFH domain / Band 7 family 105 298 3.5E-24 T 12-10-2018 IPR001107 Band 7 domain MIM_c17960 ecb3ac646802b3691e733a852c771576 441 SMART SM00244 101 286 7.3E-19 T 12-10-2018 IPR001107 Band 7 domain MIM_c17960 ecb3ac646802b3691e733a852c771576 441 Gene3D G3DSA:3.30.479.30 157 277 1.6E-14 T 12-10-2018 MIM_c17960 ecb3ac646802b3691e733a852c771576 441 TIGRFAM TIGR01933 hflK: HflK protein 103 388 1.2E-83 T 12-10-2018 IPR010201 HflK GO:0016021 MIM_c17960 ecb3ac646802b3691e733a852c771576 441 SUPERFAMILY SSF117892 162 291 7.59E-17 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily MIM_c35120 914c19389bca29f69b4d00ab4333ecc9 784 Gene3D G3DSA:3.30.1920.30 221 282 1.8E-103 T 12-10-2018 MIM_c35120 914c19389bca29f69b4d00ab4333ecc9 784 SUPERFAMILY SSF69279 12 181 2.08E-51 T 12-10-2018 MIM_c35120 914c19389bca29f69b4d00ab4333ecc9 784 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 20 503 6.0E-132 T 12-10-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein MIM_c35120 914c19389bca29f69b4d00ab4333ecc9 784 SUPERFAMILY SSF69255 363 450 2.14E-30 T 12-10-2018 MIM_c35120 914c19389bca29f69b4d00ab4333ecc9 784 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 7 518 3.1E-171 T 12-10-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset MIM_c35120 914c19389bca29f69b4d00ab4333ecc9 784 SUPERFAMILY SSF69279 185 361 2.21E-30 T 12-10-2018 MIM_c35120 914c19389bca29f69b4d00ab4333ecc9 784 Pfam PF05954 Phage late control gene D protein (GPD) 24 323 6.8E-89 T 12-10-2018 MIM_c35120 914c19389bca29f69b4d00ab4333ecc9 784 Gene3D G3DSA:3.55.50.10 95 185 1.8E-103 T 12-10-2018 MIM_c35120 914c19389bca29f69b4d00ab4333ecc9 784 SUPERFAMILY SSF69349 442 664 2.98E-25 T 12-10-2018 MIM_c35120 914c19389bca29f69b4d00ab4333ecc9 784 Gene3D G3DSA:2.40.50.230 353 455 6.6E-41 T 12-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily MIM_c35120 914c19389bca29f69b4d00ab4333ecc9 784 Gene3D G3DSA:2.30.110.50 13 323 1.8E-103 T 12-10-2018 MIM_c02130 03ed7b20b00e6f813fd87fc218c0ed31 107 Gene3D G3DSA:3.30.70.100 2 100 3.9E-29 T 12-10-2018 MIM_c02130 03ed7b20b00e6f813fd87fc218c0ed31 107 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 1 103 1.4E-33 T 12-10-2018 IPR009799 EthD domain MIM_c02130 03ed7b20b00e6f813fd87fc218c0ed31 107 Pfam PF07110 EthD domain 18 92 3.5E-8 T 12-10-2018 IPR009799 EthD domain MIM_c02130 03ed7b20b00e6f813fd87fc218c0ed31 107 SUPERFAMILY SSF54909 1 102 4.29E-21 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel MIM_c21130 4f65639700540dbc2d59b448ae64fd13 259 Gene3D G3DSA:3.40.50.720 1 258 4.6E-75 T 12-10-2018 MIM_c21130 4f65639700540dbc2d59b448ae64fd13 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 2.6E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c21130 4f65639700540dbc2d59b448ae64fd13 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 2.6E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c21130 4f65639700540dbc2d59b448ae64fd13 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 2.6E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c21130 4f65639700540dbc2d59b448ae64fd13 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c21130 4f65639700540dbc2d59b448ae64fd13 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 22 256 4.7E-55 T 12-10-2018 MIM_c21130 4f65639700540dbc2d59b448ae64fd13 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 6.2E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c21130 4f65639700540dbc2d59b448ae64fd13 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 6.2E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c21130 4f65639700540dbc2d59b448ae64fd13 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 6.2E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c21130 4f65639700540dbc2d59b448ae64fd13 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 6.2E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c21130 4f65639700540dbc2d59b448ae64fd13 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 6.2E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c21130 4f65639700540dbc2d59b448ae64fd13 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 6.2E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c21130 4f65639700540dbc2d59b448ae64fd13 259 SUPERFAMILY SSF51735 14 257 9.48E-73 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c11500 d5ed9a5fedb7992fbad65a02caad0a53 550 SUPERFAMILY SSF52540 1 506 2.31E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c11500 d5ed9a5fedb7992fbad65a02caad0a53 550 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 506 1.1E-16 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal MIM_c11500 d5ed9a5fedb7992fbad65a02caad0a53 550 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 547 6.4E-153 T 12-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 MIM_c11500 d5ed9a5fedb7992fbad65a02caad0a53 550 Gene3D G3DSA:3.40.50.300 268 548 1.8E-57 T 12-10-2018 MIM_c11500 d5ed9a5fedb7992fbad65a02caad0a53 550 Gene3D G3DSA:3.40.50.300 1 262 3.3E-44 T 12-10-2018 MIM_c11500 d5ed9a5fedb7992fbad65a02caad0a53 550 PIRSF PIRSF003128 1 550 5.7E-166 T 12-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 MIM_c30680 50a991d4b6164956e68af8017b3a5889 384 PIRSF PIRSF039026 16 376 2.1E-126 T 12-10-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like MIM_c30680 50a991d4b6164956e68af8017b3a5889 384 Gene3D G3DSA:3.40.190.170 49 355 1.6E-102 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily MIM_c30680 50a991d4b6164956e68af8017b3a5889 384 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 53 336 4.5E-39 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 MIM_c30680 50a991d4b6164956e68af8017b3a5889 384 Gene3D G3DSA:3.40.190.10 170 341 1.6E-102 T 12-10-2018 MIM_c29940 ab5ae6543b10918c3d7066f18b9041dd 137 TIGRFAM TIGR02799 thio_ybgC: tol-pal system-associated acyl-CoA thioesterase 6 130 1.2E-49 T 12-10-2018 IPR014166 Tol-Pal system-associated acyl-CoA thioesterase GO:0016790 MIM_c29940 ab5ae6543b10918c3d7066f18b9041dd 137 Pfam PF03061 Thioesterase superfamily 20 105 6.0E-16 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MIM_c29940 ab5ae6543b10918c3d7066f18b9041dd 137 SUPERFAMILY SSF54637 4 132 4.27E-41 T 12-10-2018 IPR029069 HotDog domain superfamily MIM_c29940 ab5ae6543b10918c3d7066f18b9041dd 137 PIRSF PIRSF003230 1 136 3.3E-44 T 12-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 MIM_c29940 ab5ae6543b10918c3d7066f18b9041dd 137 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 9 124 4.7E-32 T 12-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 MIM_c29940 ab5ae6543b10918c3d7066f18b9041dd 137 Gene3D G3DSA:3.10.129.10 2 134 1.7E-42 T 12-10-2018 MIM_c02160 2bf147247f918125fd07da9e1f2a3a3d 262 SMART SM00342 175 257 2.2E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c02160 2bf147247f918125fd07da9e1f2a3a3d 262 SUPERFAMILY SSF46689 211 258 9.41E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c02160 2bf147247f918125fd07da9e1f2a3a3d 262 SUPERFAMILY SSF51182 16 184 4.89E-16 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c02160 2bf147247f918125fd07da9e1f2a3a3d 262 Gene3D G3DSA:2.60.120.10 11 106 2.5E-5 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c02160 2bf147247f918125fd07da9e1f2a3a3d 262 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 212 253 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MIM_c02160 2bf147247f918125fd07da9e1f2a3a3d 262 Pfam PF12833 Helix-turn-helix domain 181 257 3.6E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c02160 2bf147247f918125fd07da9e1f2a3a3d 262 Gene3D G3DSA:1.10.10.60 161 262 3.5E-19 T 12-10-2018 MIM_c02160 2bf147247f918125fd07da9e1f2a3a3d 262 Pfam PF02311 AraC-like ligand binding domain 34 142 2.1E-9 T 12-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 MIM_c07260 ba9c2658afef0d5f2e59bd4ed58abe48 489 Pfam PF02386 Cation transport protein 310 483 6.6E-20 T 12-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 MIM_c07260 ba9c2658afef0d5f2e59bd4ed58abe48 489 Pfam PF02386 Cation transport protein 40 272 9.7E-37 T 12-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 MIM_c07260 ba9c2658afef0d5f2e59bd4ed58abe48 489 PIRSF PIRSF006247 1 489 3.4E-153 T 12-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 MIM_c04170 e1b9a033462d33271b2b291e413d4ef6 454 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 17 422 3.5E-72 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 MIM_c04170 e1b9a033462d33271b2b291e413d4ef6 454 SUPERFAMILY SSF103473 15 449 1.06E-64 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c04170 e1b9a033462d33271b2b291e413d4ef6 454 Pfam PF07690 Major Facilitator Superfamily 20 408 8.0E-56 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c04170 e1b9a033462d33271b2b291e413d4ef6 454 Gene3D G3DSA:1.20.1720.10 16 254 3.5E-43 T 12-10-2018 MIM_c04170 e1b9a033462d33271b2b291e413d4ef6 454 Gene3D G3DSA:1.20.1250.20 255 452 1.1E-22 T 12-10-2018 MIM_c32930 13cfe00c4fcbd649eaa252f43fa25752 110 Gene3D G3DSA:2.40.128.380 1 106 9.6E-10 T 12-10-2018 MIM_c32930 13cfe00c4fcbd649eaa252f43fa25752 110 Pfam PF16518 T3SS negative regulator,GrlR 1 89 1.8E-10 T 12-10-2018 IPR032417 T3SS negative regulator GrlR MIM_c16770 47c2bf5a0021d157bcff25356d1ad486 576 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 13 514 7.5E-116 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit MIM_c15560 09d6bd94c2e523e509340d4c2674cfd7 156 SUPERFAMILY SSF55729 20 155 6.73E-35 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c15560 09d6bd94c2e523e509340d4c2674cfd7 156 Pfam PF13673 Acetyltransferase (GNAT) domain 38 155 2.8E-18 T 12-10-2018 IPR000182 GNAT domain MIM_c15560 09d6bd94c2e523e509340d4c2674cfd7 156 Gene3D G3DSA:3.40.630.30 18 155 9.7E-37 T 12-10-2018 MIM_c28960 112a12e329a3c3e721d91b4570627807 153 Gene3D G3DSA:2.60.40.1890 31 145 2.0E-37 T 12-10-2018 IPR036182 Copper chaperone PCuAC superfamily MIM_c28960 112a12e329a3c3e721d91b4570627807 153 SUPERFAMILY SSF110087 7 140 7.59E-43 T 12-10-2018 IPR036182 Copper chaperone PCuAC superfamily MIM_c28960 112a12e329a3c3e721d91b4570627807 153 Pfam PF04314 Copper chaperone PCu(A)C 27 128 1.5E-35 T 12-10-2018 IPR007410 Copper chaperone PCuAC MIM_c18640 b9b9dd3367408075e3fd9c75230fcb15 445 SUPERFAMILY SSF103473 33 443 4.32E-63 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c18640 b9b9dd3367408075e3fd9c75230fcb15 445 Gene3D G3DSA:1.20.1250.20 32 445 5.0E-61 T 12-10-2018 MIM_c18640 b9b9dd3367408075e3fd9c75230fcb15 445 Pfam PF07690 Major Facilitator Superfamily 40 396 2.4E-27 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c18640 b9b9dd3367408075e3fd9c75230fcb15 445 ProSitePatterns PS00217 Sugar transport proteins signature 2. 144 169 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MIM_c01120 b28bc5c0ea82b06059f320808c5828da 310 SUPERFAMILY SSF51197 9 305 5.59E-48 T 12-10-2018 MIM_c01120 b28bc5c0ea82b06059f320808c5828da 310 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 16 264 2.5E-24 T 12-10-2018 IPR008775 Phytanoyl-CoA dioxygenase MIM_c13390 a4a51750dcccdd9b9fdc75caa9bdcd1e 516 Gene3D G3DSA:3.10.105.10 278 490 9.4E-130 T 12-10-2018 MIM_c13390 a4a51750dcccdd9b9fdc75caa9bdcd1e 516 Gene3D G3DSA:3.90.76.10 50 196 9.4E-130 T 12-10-2018 MIM_c13390 a4a51750dcccdd9b9fdc75caa9bdcd1e 516 Gene3D G3DSA:3.40.190.10 197 503 9.4E-130 T 12-10-2018 MIM_c13390 a4a51750dcccdd9b9fdc75caa9bdcd1e 516 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 432 5.0E-93 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain MIM_c13390 a4a51750dcccdd9b9fdc75caa9bdcd1e 516 PIRSF PIRSF002741 2 514 6.7E-114 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MIM_c13390 a4a51750dcccdd9b9fdc75caa9bdcd1e 516 SUPERFAMILY SSF53850 28 504 6.52E-129 T 12-10-2018 MIM_c04380 318e5cbe47c97182878ef762399039ea 213 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 4 187 1.4E-52 T 12-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 MIM_c04380 318e5cbe47c97182878ef762399039ea 213 SUPERFAMILY SSF52016 4 191 5.69E-42 T 12-10-2018 MIM_c04380 318e5cbe47c97182878ef762399039ea 213 Pfam PF00694 Aconitase C-terminal domain 6 124 9.2E-24 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 MIM_c04380 318e5cbe47c97182878ef762399039ea 213 Gene3D G3DSA:3.20.19.10 1 175 3.9E-57 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 MIM_c29430 485fc45d81c9e327e8e9a356719ba170 149 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 148 8.0E-54 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 MIM_c29430 485fc45d81c9e327e8e9a356719ba170 149 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 78 91 9.4E-18 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 MIM_c29430 485fc45d81c9e327e8e9a356719ba170 149 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 95 109 9.4E-18 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 MIM_c29430 485fc45d81c9e327e8e9a356719ba170 149 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 110 123 9.4E-18 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 MIM_c29430 485fc45d81c9e327e8e9a356719ba170 149 Gene3D G3DSA:2.40.50.100 72 148 1.3E-31 T 12-10-2018 MIM_c29430 485fc45d81c9e327e8e9a356719ba170 149 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 105 122 - T 12-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MIM_c29430 485fc45d81c9e327e8e9a356719ba170 149 SUPERFAMILY SSF51230 74 148 6.94E-25 T 12-10-2018 IPR011053 Single hybrid motif MIM_c29430 485fc45d81c9e327e8e9a356719ba170 149 Pfam PF00364 Biotin-requiring enzyme 76 148 4.8E-24 T 12-10-2018 IPR000089 Biotin/lipoyl attachment MIM_c08820 f205e8ba175581c836566d450e18654f 514 Hamap MF_00578 Glutamate--cysteine ligase [gshA]. 1 514 193.193 T 12-10-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MIM_c08820 f205e8ba175581c836566d450e18654f 514 TIGRFAM TIGR01434 glu_cys_ligase: glutamate--cysteine ligase 3 505 1.1E-182 T 12-10-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MIM_c08820 f205e8ba175581c836566d450e18654f 514 SUPERFAMILY SSF55931 5 503 6.41E-177 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 MIM_c08820 f205e8ba175581c836566d450e18654f 514 Gene3D G3DSA:3.30.590.20 9 512 7.3E-185 T 12-10-2018 MIM_c08820 f205e8ba175581c836566d450e18654f 514 Pfam PF04262 Glutamate-cysteine ligase 5 366 2.4E-155 T 12-10-2018 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MIM_24p00100 77e84dec6e629699e595462442f0d9d6 212 Gene3D G3DSA:3.20.19.10 1 184 7.9E-70 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 MIM_24p00100 77e84dec6e629699e595462442f0d9d6 212 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 210 39.871 T 12-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 MIM_24p00100 77e84dec6e629699e595462442f0d9d6 212 SUPERFAMILY SSF52016 1 203 8.44E-56 T 12-10-2018 MIM_24p00100 77e84dec6e629699e595462442f0d9d6 212 Pfam PF00694 Aconitase C-terminal domain 2 130 3.9E-33 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 MIM_24p00100 77e84dec6e629699e595462442f0d9d6 212 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 196 1.4E-72 T 12-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 MIM_c31030 7de60e47ece28797b70055931f06532a 404 SUPERFAMILY SSF53822 30 400 7.74E-80 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c31030 7de60e47ece28797b70055931f06532a 404 Pfam PF13458 Periplasmic binding protein 30 365 4.2E-78 T 12-10-2018 IPR028081 Leucine-binding protein domain MIM_c31030 7de60e47ece28797b70055931f06532a 404 Gene3D G3DSA:3.40.50.2300 149 366 6.0E-102 T 12-10-2018 MIM_c31030 7de60e47ece28797b70055931f06532a 404 Gene3D G3DSA:3.40.50.2300 54 358 6.0E-102 T 12-10-2018 MIM_c40130 3d90136cec99df0e1cfe1ae123b7d399 400 SUPERFAMILY SSF89796 9 400 9.29E-121 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c40130 3d90136cec99df0e1cfe1ae123b7d399 400 Pfam PF02515 CoA-transferase family III 12 376 4.4E-105 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 MIM_c40130 3d90136cec99df0e1cfe1ae123b7d399 400 Gene3D G3DSA:3.30.1540.10 237 330 4.9E-115 T 12-10-2018 MIM_c40130 3d90136cec99df0e1cfe1ae123b7d399 400 Gene3D G3DSA:3.40.50.10540 11 392 4.9E-115 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c14960 4a7ef44c15dde9787491228f0266575f 140 ProSitePatterns PS01117 MarR-type HTH domain signature. 72 106 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MIM_c14960 4a7ef44c15dde9787491228f0266575f 140 SUPERFAMILY SSF46785 4 124 1.12E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c14960 4a7ef44c15dde9787491228f0266575f 140 Gene3D G3DSA:1.10.10.10 3 134 4.3E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c14960 4a7ef44c15dde9787491228f0266575f 140 SMART SM00347 30 136 2.4E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c14960 4a7ef44c15dde9787491228f0266575f 140 Pfam PF12802 MarR family 36 96 1.5E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c11770 d8066619c5914d4991aa46b5d3b10283 342 Hamap MF_00469 UPF0176 protein YceA [yceA]. 1 259 45.41 T 12-10-2018 IPR020936 Uncharacterised protein family UPF0176 MIM_c11770 d8066619c5914d4991aa46b5d3b10283 342 Gene3D G3DSA:3.40.250.10 99 250 4.6E-47 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily MIM_c11770 d8066619c5914d4991aa46b5d3b10283 342 Gene3D G3DSA:3.30.70.100 1 96 1.4E-35 T 12-10-2018 MIM_c11770 d8066619c5914d4991aa46b5d3b10283 342 SUPERFAMILY SSF52821 106 248 2.06E-28 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily MIM_c11770 d8066619c5914d4991aa46b5d3b10283 342 Pfam PF00581 Rhodanese-like domain 119 215 2.5E-7 T 12-10-2018 IPR001763 Rhodanese-like domain MIM_c11770 d8066619c5914d4991aa46b5d3b10283 342 SMART SM00450 112 219 2.1E-22 T 12-10-2018 IPR001763 Rhodanese-like domain MIM_c12540 169be5be6015911c126d2bc04b3419df 266 Gene3D G3DSA:3.90.226.10 1 207 3.8E-65 T 12-10-2018 MIM_c12540 169be5be6015911c126d2bc04b3419df 266 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 265 1.2E-62 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c12540 169be5be6015911c126d2bc04b3419df 266 TIGRFAM TIGR02280 PaaB1: phenylacetate degradation probable enoyl-CoA hydratase PaaB 9 266 3.1E-104 T 12-10-2018 IPR011968 Phenylacetate degradation probable enoyl-CoA hydratase PaaB GO:0010124 KEGG: 00360+5.3.3.18 MIM_c12540 169be5be6015911c126d2bc04b3419df 266 Gene3D G3DSA:1.10.12.10 210 266 2.2E-20 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MIM_c12540 169be5be6015911c126d2bc04b3419df 266 SUPERFAMILY SSF52096 4 266 1.36E-81 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c24600 35669d4f676192d63c8854ea1a65810e 402 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 162 173 9.0E-5 T 12-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 MIM_c24600 35669d4f676192d63c8854ea1a65810e 402 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 58 69 9.0E-5 T 12-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 MIM_c24600 35669d4f676192d63c8854ea1a65810e 402 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 102 112 9.0E-5 T 12-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 MIM_c24600 35669d4f676192d63c8854ea1a65810e 402 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 354 371 9.0E-5 T 12-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 MIM_c24600 35669d4f676192d63c8854ea1a65810e 402 Gene3D G3DSA:2.40.160.10 11 402 8.0E-84 T 12-10-2018 IPR023614 Porin domain superfamily MIM_c24600 35669d4f676192d63c8854ea1a65810e 402 SUPERFAMILY SSF56935 21 402 2.08E-68 T 12-10-2018 MIM_c24600 35669d4f676192d63c8854ea1a65810e 402 Pfam PF13609 Gram-negative porin 7 374 6.2E-52 T 12-10-2018 MIM_c24600 35669d4f676192d63c8854ea1a65810e 402 PRINTS PR00184 Neisseria sp. porin signature 60 85 1.8E-10 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 MIM_c24600 35669d4f676192d63c8854ea1a65810e 402 PRINTS PR00184 Neisseria sp. porin signature 161 178 1.8E-10 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 MIM_c24600 35669d4f676192d63c8854ea1a65810e 402 PRINTS PR00184 Neisseria sp. porin signature 351 375 1.8E-10 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 MIM_c31720 55b58f429ee0a1e1812cd4fc69fb8382 357 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 328 5.2E-80 T 12-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 MIM_c31720 55b58f429ee0a1e1812cd4fc69fb8382 357 Gene3D G3DSA:3.20.20.70 1 357 2.3E-122 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c31720 55b58f429ee0a1e1812cd4fc69fb8382 357 SUPERFAMILY SSF51395 1 353 1.27E-110 T 12-10-2018 MIM_c24490 41c5d772ad90cb23ec07d621bc393350 108 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 103 3.3E-25 T 12-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like MIM_c24490 41c5d772ad90cb23ec07d621bc393350 108 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 3 108 20.379 T 12-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 MIM_c18320 ecf1f197917886c6f6f64f809ef0dd64 318 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 7 213 7.7E-75 T 12-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MIM_c18320 ecf1f197917886c6f6f64f809ef0dd64 318 Gene3D G3DSA:3.40.190.10 104 203 1.5E-81 T 12-10-2018 MIM_c18320 ecf1f197917886c6f6f64f809ef0dd64 318 PIRSF PIRSF001438 1 313 2.1E-116 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MIM_c18320 ecf1f197917886c6f6f64f809ef0dd64 318 PRINTS PR00151 Porphobilinogen deaminase signature 144 161 4.3E-45 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MIM_c18320 ecf1f197917886c6f6f64f809ef0dd64 318 PRINTS PR00151 Porphobilinogen deaminase signature 231 248 4.3E-45 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MIM_c18320 ecf1f197917886c6f6f64f809ef0dd64 318 PRINTS PR00151 Porphobilinogen deaminase signature 77 96 4.3E-45 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MIM_c18320 ecf1f197917886c6f6f64f809ef0dd64 318 PRINTS PR00151 Porphobilinogen deaminase signature 46 66 4.3E-45 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MIM_c18320 ecf1f197917886c6f6f64f809ef0dd64 318 PRINTS PR00151 Porphobilinogen deaminase signature 125 142 4.3E-45 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MIM_c18320 ecf1f197917886c6f6f64f809ef0dd64 318 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 7 298 7.4E-110 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MIM_c18320 ecf1f197917886c6f6f64f809ef0dd64 318 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 227 296 2.9E-19 T 12-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MIM_c18320 ecf1f197917886c6f6f64f809ef0dd64 318 SUPERFAMILY SSF53850 6 218 5.09E-80 T 12-10-2018 MIM_c18320 ecf1f197917886c6f6f64f809ef0dd64 318 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 232 248 - T 12-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MIM_c18320 ecf1f197917886c6f6f64f809ef0dd64 318 Gene3D G3DSA:3.30.160.40 223 307 5.8E-27 T 12-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MIM_c18320 ecf1f197917886c6f6f64f809ef0dd64 318 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 6 298 37.836 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MIM_c18320 ecf1f197917886c6f6f64f809ef0dd64 318 Gene3D G3DSA:3.40.190.10 8 209 1.5E-81 T 12-10-2018 MIM_c18320 ecf1f197917886c6f6f64f809ef0dd64 318 SUPERFAMILY SSF54782 222 308 1.1E-26 T 12-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MIM_c22990 4bb076f22cc945dab7ea09e45d261bb5 456 SMART SM00304 185 238 5.0E-4 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MIM_c22990 4bb076f22cc945dab7ea09e45d261bb5 456 Pfam PF00512 His Kinase A (phospho-acceptor) domain 246 305 5.2E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MIM_c22990 4bb076f22cc945dab7ea09e45d261bb5 456 SUPERFAMILY SSF47384 222 305 2.35E-12 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MIM_c22990 4bb076f22cc945dab7ea09e45d261bb5 456 SMART SM00388 239 305 9.0E-6 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MIM_c22990 4bb076f22cc945dab7ea09e45d261bb5 456 SMART SM00387 350 455 1.8E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c22990 4bb076f22cc945dab7ea09e45d261bb5 456 SUPERFAMILY SSF55874 295 453 1.31E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c22990 4bb076f22cc945dab7ea09e45d261bb5 456 Gene3D G3DSA:3.30.565.10 312 455 1.3E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c22990 4bb076f22cc945dab7ea09e45d261bb5 456 SUPERFAMILY SSF158472 191 236 4.05E-5 T 12-10-2018 MIM_c22990 4bb076f22cc945dab7ea09e45d261bb5 456 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 350 454 8.5E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c22990 4bb076f22cc945dab7ea09e45d261bb5 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 1.1E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c22990 4bb076f22cc945dab7ea09e45d261bb5 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 434 1.1E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c22990 4bb076f22cc945dab7ea09e45d261bb5 456 Gene3D G3DSA:1.10.287.130 191 305 1.1E-19 T 12-10-2018 MIM_c38710 23f3fed84ad3dd493113b7d2036b6578 305 Gene3D G3DSA:3.60.130.10 23 305 9.6E-87 T 12-10-2018 MIM_c38710 23f3fed84ad3dd493113b7d2036b6578 305 SUPERFAMILY SSF51197 25 305 1.01E-84 T 12-10-2018 MIM_c38710 23f3fed84ad3dd493113b7d2036b6578 305 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 26 298 4.4E-63 T 12-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 MIM_c37760 a8c89ac86cc9e1e314ed4d452bb19e90 446 SUPERFAMILY SSF52402 58 300 3.14E-7 T 12-10-2018 MIM_c18610 8053e4fd26289a3aec7dedc04356c3c5 254 Gene3D G3DSA:2.40.30.130 1 106 3.6E-16 T 12-10-2018 MIM_c18610 8053e4fd26289a3aec7dedc04356c3c5 254 SUPERFAMILY SSF55186 114 240 2.88E-24 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 MIM_c18610 8053e4fd26289a3aec7dedc04356c3c5 254 SUPERFAMILY SSF50447 5 68 4.24E-10 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MIM_c18610 8053e4fd26289a3aec7dedc04356c3c5 254 Gene3D G3DSA:3.30.980.10 114 243 2.3E-21 T 12-10-2018 MIM_c27120 fc88c6b37f54e275c07c52712673907c 231 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 16 121 1.0E-17 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c27120 fc88c6b37f54e275c07c52712673907c 231 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 38 225 1.1E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c27120 fc88c6b37f54e275c07c52712673907c 231 SUPERFAMILY SSF161098 16 212 1.31E-39 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c27120 fc88c6b37f54e275c07c52712673907c 231 Gene3D G3DSA:1.10.3720.10 9 227 3.0E-47 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c31130 4c25806518a22b3145e6b51e53d3377b 132 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 90 2.3E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c31130 4c25806518a22b3145e6b51e53d3377b 132 PRINTS PR00598 Bacterial regulatory protein MarR family signature 104 124 2.3E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c31130 4c25806518a22b3145e6b51e53d3377b 132 PRINTS PR00598 Bacterial regulatory protein MarR family signature 38 54 2.3E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c31130 4c25806518a22b3145e6b51e53d3377b 132 PRINTS PR00598 Bacterial regulatory protein MarR family signature 55 70 2.3E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c31130 4c25806518a22b3145e6b51e53d3377b 132 Pfam PF12802 MarR family 21 77 5.6E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c31130 4c25806518a22b3145e6b51e53d3377b 132 SMART SM00347 14 114 2.5E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c31130 4c25806518a22b3145e6b51e53d3377b 132 Gene3D G3DSA:1.10.10.10 1 129 4.0E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c31130 4c25806518a22b3145e6b51e53d3377b 132 SUPERFAMILY SSF46785 1 125 5.55E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c07880 7acb5a4967e97d7e02622fe32a8f1d21 286 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 2.2E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c07880 7acb5a4967e97d7e02622fe32a8f1d21 286 Gene3D G3DSA:1.10.10.10 1 80 3.7E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c07880 7acb5a4967e97d7e02622fe32a8f1d21 286 SUPERFAMILY SSF46785 2 110 4.03E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c07880 7acb5a4967e97d7e02622fe32a8f1d21 286 SUPERFAMILY SSF53850 88 284 2.48E-30 T 12-10-2018 MIM_c07880 7acb5a4967e97d7e02622fe32a8f1d21 286 Gene3D G3DSA:3.40.190.290 90 286 3.8E-27 T 12-10-2018 MIM_c07880 7acb5a4967e97d7e02622fe32a8f1d21 286 Pfam PF03466 LysR substrate binding domain 87 284 4.9E-29 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c00360 8e87db7ad9544c2ea6bb5529772e9f81 260 SUPERFAMILY SSF46785 26 95 1.5E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c00360 8e87db7ad9544c2ea6bb5529772e9f81 260 Pfam PF01614 Bacterial transcriptional regulator 174 240 1.0E-10 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal MIM_c00360 8e87db7ad9544c2ea6bb5529772e9f81 260 Gene3D G3DSA:1.10.10.10 9 84 7.6E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c00360 8e87db7ad9544c2ea6bb5529772e9f81 260 Gene3D G3DSA:3.30.450.40 91 170 4.7E-18 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c00360 8e87db7ad9544c2ea6bb5529772e9f81 260 SUPERFAMILY SSF55781 90 241 2.88E-32 T 12-10-2018 MIM_c00360 8e87db7ad9544c2ea6bb5529772e9f81 260 Pfam PF09339 IclR helix-turn-helix domain 26 75 9.6E-12 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c00360 8e87db7ad9544c2ea6bb5529772e9f81 260 SMART SM00346 24 113 5.3E-13 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c00360 8e87db7ad9544c2ea6bb5529772e9f81 260 Gene3D G3DSA:3.30.450.40 171 245 5.4E-14 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c23570 1623ffe72f80c25413653454182e19c1 217 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 3 212 2.1E-98 T 12-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 MIM_c23570 1623ffe72f80c25413653454182e19c1 217 SUPERFAMILY SSF100950 3 214 6.28E-71 T 12-10-2018 IPR037171 NagB/RpiA transferase-like MIM_c23570 1623ffe72f80c25413653454182e19c1 217 Pfam PF01144 Coenzyme A transferase 7 205 5.6E-40 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MIM_c23570 1623ffe72f80c25413653454182e19c1 217 SMART SM00882 6 206 7.5E-79 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MIM_c23570 1623ffe72f80c25413653454182e19c1 217 Gene3D G3DSA:3.40.1080.10 2 216 5.4E-100 T 12-10-2018 MIM_c23570 1623ffe72f80c25413653454182e19c1 217 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 44 52 - T 12-10-2018 IPR004164 Coenzyme A transferase active site GO:0008410 Reactome: R-HSA-77108 MIM_c35050 3a5d1a9a8d154a878415f091863d724a 181 Pfam PF02627 Carboxymuconolactone decarboxylase family 47 104 6.1E-7 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c35050 3a5d1a9a8d154a878415f091863d724a 181 Gene3D G3DSA:1.20.1290.10 32 177 1.7E-30 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c35050 3a5d1a9a8d154a878415f091863d724a 181 SUPERFAMILY SSF69118 1 171 3.21E-34 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c35050 3a5d1a9a8d154a878415f091863d724a 181 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 60 97 6.0E-8 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c03340 49c995a498fc98d90114a60be3feba69 207 Gene3D G3DSA:2.30.110.10 1 207 1.2E-66 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MIM_c03340 49c995a498fc98d90114a60be3feba69 207 SUPERFAMILY SSF50475 1 195 8.29E-45 T 12-10-2018 MIM_c03340 49c995a498fc98d90114a60be3feba69 207 Pfam PF01613 Flavin reductase like domain 22 161 1.1E-21 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MIM_c03340 49c995a498fc98d90114a60be3feba69 207 SMART SM00903 19 172 3.4E-22 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MIM_c11740 48f892831af01e4306e7c150a3dfb305 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 27 87 1.6E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c11740 48f892831af01e4306e7c150a3dfb305 234 Pfam PF07729 FCD domain 99 219 1.0E-26 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c11740 48f892831af01e4306e7c150a3dfb305 234 Gene3D G3DSA:1.20.120.530 97 229 1.9E-30 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c11740 48f892831af01e4306e7c150a3dfb305 234 Gene3D G3DSA:1.10.10.10 23 90 9.4E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c11740 48f892831af01e4306e7c150a3dfb305 234 SMART SM00895 99 220 1.1E-22 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c11740 48f892831af01e4306e7c150a3dfb305 234 SMART SM00345 31 89 4.2E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c11740 48f892831af01e4306e7c150a3dfb305 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 63 79 2.8E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c11740 48f892831af01e4306e7c150a3dfb305 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 63 2.8E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c11740 48f892831af01e4306e7c150a3dfb305 234 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 49 60 6.0E-5 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MIM_c11740 48f892831af01e4306e7c150a3dfb305 234 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 60 79 6.0E-5 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MIM_c11740 48f892831af01e4306e7c150a3dfb305 234 SUPERFAMILY SSF46785 23 114 7.81E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c11740 48f892831af01e4306e7c150a3dfb305 234 SUPERFAMILY SSF48008 98 224 5.49E-28 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c06630 950f6134a8a0ee1a5c2fffc5da6af124 265 SUPERFAMILY SSF51735 11 264 9.87E-70 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c06630 950f6134a8a0ee1a5c2fffc5da6af124 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 8.7E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c06630 950f6134a8a0ee1a5c2fffc5da6af124 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 8.7E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c06630 950f6134a8a0ee1a5c2fffc5da6af124 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 8.7E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c06630 950f6134a8a0ee1a5c2fffc5da6af124 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 8.7E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c06630 950f6134a8a0ee1a5c2fffc5da6af124 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 8.7E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c06630 950f6134a8a0ee1a5c2fffc5da6af124 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 8.7E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c06630 950f6134a8a0ee1a5c2fffc5da6af124 265 Gene3D G3DSA:3.40.50.720 2 265 1.5E-75 T 12-10-2018 MIM_c06630 950f6134a8a0ee1a5c2fffc5da6af124 265 Pfam PF00106 short chain dehydrogenase 12 203 4.0E-54 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c06630 950f6134a8a0ee1a5c2fffc5da6af124 265 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c06630 950f6134a8a0ee1a5c2fffc5da6af124 265 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 12 265 2.1E-98 T 12-10-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 MIM_c06630 950f6134a8a0ee1a5c2fffc5da6af124 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 2.8E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c06630 950f6134a8a0ee1a5c2fffc5da6af124 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 2.8E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c06630 950f6134a8a0ee1a5c2fffc5da6af124 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 2.8E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c34030 1dcea56ef448f23a04103d13fea7f605 281 SUPERFAMILY SSF51735 12 271 1.06E-21 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c34030 1dcea56ef448f23a04103d13fea7f605 281 Gene3D G3DSA:3.40.50.720 2 281 3.9E-58 T 12-10-2018 MIM_c10110 a0f2f2435140917d99e4af189d3946be 301 Gene3D G3DSA:3.20.20.370 5 250 1.0E-24 T 12-10-2018 MIM_c10110 a0f2f2435140917d99e4af189d3946be 301 SUPERFAMILY SSF88713 16 253 1.11E-18 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MIM_c20290 f3d49f59f780f8b9e0d888240c06a0e2 285 SUPERFAMILY SSF53822 28 279 4.04E-59 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c20290 f3d49f59f780f8b9e0d888240c06a0e2 285 Gene3D G3DSA:3.40.50.2300 30 147 3.2E-63 T 12-10-2018 MIM_c20290 f3d49f59f780f8b9e0d888240c06a0e2 285 Pfam PF13458 Periplasmic binding protein 28 279 3.6E-51 T 12-10-2018 IPR028081 Leucine-binding protein domain MIM_c20290 f3d49f59f780f8b9e0d888240c06a0e2 285 Gene3D G3DSA:3.40.50.2300 148 275 3.2E-63 T 12-10-2018 MIM_c20290 f3d49f59f780f8b9e0d888240c06a0e2 285 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 29 45 2.2E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MIM_c20290 f3d49f59f780f8b9e0d888240c06a0e2 285 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 51 67 2.2E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MIM_c38750 d982b6add59813b852e377eec9143c7a 450 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 158 448 1.9E-70 T 12-10-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 MIM_c38750 d982b6add59813b852e377eec9143c7a 450 Pfam PF01578 Cytochrome C assembly protein 188 445 8.3E-42 T 12-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 MIM_c34000 b4a246a76b673ad3e4d2a5667d7813d1 152 Gene3D G3DSA:3.30.310.70 28 150 3.2E-14 T 12-10-2018 IPR035923 TT1751-like domain superfamily MIM_c34000 b4a246a76b673ad3e4d2a5667d7813d1 152 SUPERFAMILY SSF103247 31 148 9.94E-30 T 12-10-2018 IPR035923 TT1751-like domain superfamily MIM_c34000 b4a246a76b673ad3e4d2a5667d7813d1 152 Pfam PF03625 Domain of unknown function DUF302 60 118 5.8E-16 T 12-10-2018 IPR005180 Domain of unknown function DUF302 MIM_c01360 cff2fe8ef5ca2697fffcecf0e91db782 331 Gene3D G3DSA:1.10.10.10 1 91 1.8E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c01360 cff2fe8ef5ca2697fffcecf0e91db782 331 SUPERFAMILY SSF53850 94 296 6.05E-29 T 12-10-2018 MIM_c01360 cff2fe8ef5ca2697fffcecf0e91db782 331 Gene3D G3DSA:3.40.190.290 92 300 2.0E-28 T 12-10-2018 MIM_c01360 cff2fe8ef5ca2697fffcecf0e91db782 331 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.9E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c01360 cff2fe8ef5ca2697fffcecf0e91db782 331 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.9E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c01360 cff2fe8ef5ca2697fffcecf0e91db782 331 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.9E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c01360 cff2fe8ef5ca2697fffcecf0e91db782 331 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.7E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c01360 cff2fe8ef5ca2697fffcecf0e91db782 331 SUPERFAMILY SSF46785 1 84 8.71E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c01360 cff2fe8ef5ca2697fffcecf0e91db782 331 Pfam PF03466 LysR substrate binding domain 114 293 6.4E-26 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c22760 cdd6eecbc7eb2cf44e991440298d281f 406 SUPERFAMILY SSF48452 40 209 2.18E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MIM_c22760 cdd6eecbc7eb2cf44e991440298d281f 406 SMART SM00028 225 258 250.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MIM_c22760 cdd6eecbc7eb2cf44e991440298d281f 406 SMART SM00028 36 69 51.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MIM_c22760 cdd6eecbc7eb2cf44e991440298d281f 406 SMART SM00028 70 103 59.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MIM_c22760 cdd6eecbc7eb2cf44e991440298d281f 406 SMART SM00028 108 141 120.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MIM_c22760 cdd6eecbc7eb2cf44e991440298d281f 406 Pfam PF13176 Tetratricopeptide repeat 73 97 0.016 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MIM_c22760 cdd6eecbc7eb2cf44e991440298d281f 406 Hamap MF_00994 Lipopolysaccharide assembly protein B [lapB]. 6 406 30.948 T 12-10-2018 IPR030865 Lipopolysaccharide assembly protein B GO:0008653 MIM_c22760 cdd6eecbc7eb2cf44e991440298d281f 406 Gene3D G3DSA:1.25.40.10 19 323 4.6E-21 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MIM_c06810 17198d4976d88fc3d8d331ef05d68c49 379 Pfam PF13439 Glycosyltransferase Family 4 14 168 7.7E-20 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MIM_c06810 17198d4976d88fc3d8d331ef05d68c49 379 Gene3D G3DSA:3.40.50.2000 185 350 8.8E-28 T 12-10-2018 MIM_c06810 17198d4976d88fc3d8d331ef05d68c49 379 Gene3D G3DSA:3.40.50.2000 1 184 2.2E-21 T 12-10-2018 MIM_c06810 17198d4976d88fc3d8d331ef05d68c49 379 Pfam PF00534 Glycosyl transferases group 1 191 346 2.5E-21 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 MIM_c06810 17198d4976d88fc3d8d331ef05d68c49 379 SUPERFAMILY SSF53756 2 368 3.3E-62 T 12-10-2018 MIM_c35830 1ec50d6cbf0af0c20bc8bc3da482f322 452 PRINTS PR00145 Argininosuccinate lyase family signature 232 256 6.1E-10 T 12-10-2018 MIM_c35830 1ec50d6cbf0af0c20bc8bc3da482f322 452 PRINTS PR00145 Argininosuccinate lyase family signature 101 123 6.1E-10 T 12-10-2018 MIM_c35830 1ec50d6cbf0af0c20bc8bc3da482f322 452 PRINTS PR00145 Argininosuccinate lyase family signature 277 293 6.1E-10 T 12-10-2018 MIM_c35830 1ec50d6cbf0af0c20bc8bc3da482f322 452 PRINTS PR00145 Argininosuccinate lyase family signature 142 162 6.1E-10 T 12-10-2018 MIM_c35830 1ec50d6cbf0af0c20bc8bc3da482f322 452 TIGRFAM TIGR02426 protocat_pcaB: 3-carboxy-cis,cis-muconate cycloisomerase 4 350 7.2E-114 T 12-10-2018 IPR012789 3-carboxy-cis,cis-muconate cycloisomerase GO:0019619|GO:0047472 KEGG: 00362+5.5.1.2 MIM_c35830 1ec50d6cbf0af0c20bc8bc3da482f322 452 SUPERFAMILY SSF48557 4 445 1.52E-113 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 MIM_c35830 1ec50d6cbf0af0c20bc8bc3da482f322 452 Gene3D G3DSA:1.20.200.10 107 362 9.4E-100 T 12-10-2018 MIM_c35830 1ec50d6cbf0af0c20bc8bc3da482f322 452 Pfam PF00206 Lyase 15 300 7.3E-53 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal MIM_c35830 1ec50d6cbf0af0c20bc8bc3da482f322 452 Gene3D G3DSA:1.10.40.30 364 444 4.3E-29 T 12-10-2018 MIM_c35830 1ec50d6cbf0af0c20bc8bc3da482f322 452 ProSitePatterns PS00163 Fumarate lyases signature. 277 286 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MIM_c35830 1ec50d6cbf0af0c20bc8bc3da482f322 452 SMART SM00998 365 444 3.0E-25 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MIM_c35830 1ec50d6cbf0af0c20bc8bc3da482f322 452 Gene3D G3DSA:1.10.275.10 7 106 1.6E-29 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal MIM_c35830 1ec50d6cbf0af0c20bc8bc3da482f322 452 Pfam PF10397 Adenylosuccinate lyase C-terminus 366 443 1.2E-17 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MIM_c35830 1ec50d6cbf0af0c20bc8bc3da482f322 452 PRINTS PR00149 Fumarate lyase superfamily signature 277 293 4.0E-23 T 12-10-2018 IPR000362 Fumarate lyase family MIM_c35830 1ec50d6cbf0af0c20bc8bc3da482f322 452 PRINTS PR00149 Fumarate lyase superfamily signature 147 165 4.0E-23 T 12-10-2018 IPR000362 Fumarate lyase family MIM_c35830 1ec50d6cbf0af0c20bc8bc3da482f322 452 PRINTS PR00149 Fumarate lyase superfamily signature 102 120 4.0E-23 T 12-10-2018 IPR000362 Fumarate lyase family MIM_c35830 1ec50d6cbf0af0c20bc8bc3da482f322 452 PRINTS PR00149 Fumarate lyase superfamily signature 232 259 4.0E-23 T 12-10-2018 IPR000362 Fumarate lyase family MIM_c10340 fa4dec7943e5e0ae8db075d319e12f8d 269 Pfam PF00994 Probable molybdopterin binding domain 11 176 1.1E-24 T 12-10-2018 IPR001453 MoaB/Mog domain MIM_c10340 fa4dec7943e5e0ae8db075d319e12f8d 269 Gene3D G3DSA:3.40.980.10 6 179 3.1E-41 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily MIM_c10340 fa4dec7943e5e0ae8db075d319e12f8d 269 SUPERFAMILY SSF53218 8 216 1.83E-31 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily MIM_c10340 fa4dec7943e5e0ae8db075d319e12f8d 269 SMART SM00852 10 183 1.7E-27 T 12-10-2018 IPR001453 MoaB/Mog domain MIM_c39720 2becbd41c2f21fa0a081802c0c846533 517 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 372 392 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MIM_c39720 2becbd41c2f21fa0a081802c0c846533 517 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 265 460 1.4E-38 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 MIM_c39720 2becbd41c2f21fa0a081802c0c846533 517 Gene3D G3DSA:3.30.420.40 1 245 1.7E-74 T 12-10-2018 MIM_c39720 2becbd41c2f21fa0a081802c0c846533 517 Gene3D G3DSA:3.30.420.40 256 514 1.1E-69 T 12-10-2018 MIM_c39720 2becbd41c2f21fa0a081802c0c846533 517 PIRSF PIRSF000538 2 513 2.9E-143 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MIM_c39720 2becbd41c2f21fa0a081802c0c846533 517 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 253 7.2E-58 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 MIM_c39720 2becbd41c2f21fa0a081802c0c846533 517 SUPERFAMILY SSF53067 256 505 2.59E-56 T 12-10-2018 MIM_c39720 2becbd41c2f21fa0a081802c0c846533 517 SUPERFAMILY SSF53067 3 256 3.46E-61 T 12-10-2018 MIM_c14360 7bb4d58f939e2ff30b261f618326c9dc 577 SUPERFAMILY SSF52540 34 293 1.33E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c14360 7bb4d58f939e2ff30b261f618326c9dc 577 Pfam PF13419 Haloacid dehalogenase-like hydrolase 328 520 9.9E-23 T 12-10-2018 MIM_c14360 7bb4d58f939e2ff30b261f618326c9dc 577 PRINTS PR00819 CbxX/CfqX superfamily signature 36 50 2.3E-74 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 MIM_c14360 7bb4d58f939e2ff30b261f618326c9dc 577 PRINTS PR00819 CbxX/CfqX superfamily signature 76 91 2.3E-74 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 MIM_c14360 7bb4d58f939e2ff30b261f618326c9dc 577 PRINTS PR00819 CbxX/CfqX superfamily signature 180 197 2.3E-74 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 MIM_c14360 7bb4d58f939e2ff30b261f618326c9dc 577 PRINTS PR00819 CbxX/CfqX superfamily signature 159 171 2.3E-74 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 MIM_c14360 7bb4d58f939e2ff30b261f618326c9dc 577 PRINTS PR00819 CbxX/CfqX superfamily signature 114 128 2.3E-74 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 MIM_c14360 7bb4d58f939e2ff30b261f618326c9dc 577 PRINTS PR00819 CbxX/CfqX superfamily signature 254 266 2.3E-74 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 MIM_c14360 7bb4d58f939e2ff30b261f618326c9dc 577 PRINTS PR00819 CbxX/CfqX superfamily signature 197 216 2.3E-74 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 MIM_c14360 7bb4d58f939e2ff30b261f618326c9dc 577 PRINTS PR00819 CbxX/CfqX superfamily signature 128 147 2.3E-74 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 MIM_c14360 7bb4d58f939e2ff30b261f618326c9dc 577 SUPERFAMILY SSF56784 321 544 3.53E-37 T 12-10-2018 IPR036412 HAD-like superfamily MIM_c14360 7bb4d58f939e2ff30b261f618326c9dc 577 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 474 521 4.2E-13 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MIM_c14360 7bb4d58f939e2ff30b261f618326c9dc 577 Gene3D G3DSA:1.10.8.60 210 301 3.0E-25 T 12-10-2018 MIM_c14360 7bb4d58f939e2ff30b261f618326c9dc 577 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 78 209 1.5E-15 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MIM_c14360 7bb4d58f939e2ff30b261f618326c9dc 577 Gene3D G3DSA:3.40.50.300 7 209 5.4E-57 T 12-10-2018 MIM_c14360 7bb4d58f939e2ff30b261f618326c9dc 577 Gene3D G3DSA:3.40.50.1000 327 539 3.3E-64 T 12-10-2018 IPR023214 HAD superfamily MIM_c14360 7bb4d58f939e2ff30b261f618326c9dc 577 PRINTS PR00820 CbxX/CfqX protein signature 246 257 1.1E-47 T 12-10-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 MIM_c14360 7bb4d58f939e2ff30b261f618326c9dc 577 PRINTS PR00820 CbxX/CfqX protein signature 90 105 1.1E-47 T 12-10-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 MIM_c14360 7bb4d58f939e2ff30b261f618326c9dc 577 PRINTS PR00820 CbxX/CfqX protein signature 31 45 1.1E-47 T 12-10-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 MIM_c14360 7bb4d58f939e2ff30b261f618326c9dc 577 PRINTS PR00820 CbxX/CfqX protein signature 261 272 1.1E-47 T 12-10-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 MIM_c14360 7bb4d58f939e2ff30b261f618326c9dc 577 PRINTS PR00820 CbxX/CfqX protein signature 147 160 1.1E-47 T 12-10-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 MIM_c14360 7bb4d58f939e2ff30b261f618326c9dc 577 PRINTS PR00820 CbxX/CfqX protein signature 285 299 1.1E-47 T 12-10-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 MIM_c14360 7bb4d58f939e2ff30b261f618326c9dc 577 PRINTS PR00820 CbxX/CfqX protein signature 49 63 1.1E-47 T 12-10-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 MIM_c14360 7bb4d58f939e2ff30b261f618326c9dc 577 TIGRFAM TIGR02880 cbbX_cfxQ: CbbX protein 25 299 3.6E-153 T 12-10-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 MIM_c14360 7bb4d58f939e2ff30b261f618326c9dc 577 SMART SM00382 73 212 5.8E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c14360 7bb4d58f939e2ff30b261f618326c9dc 577 Gene3D G3DSA:1.10.150.240 339 419 3.3E-64 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MIM_c40330 9a24c010d018e89d78a820891bd794fc 265 Gene3D G3DSA:3.40.50.720 2 264 2.5E-76 T 12-10-2018 MIM_c40330 9a24c010d018e89d78a820891bd794fc 265 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 156 184 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c40330 9a24c010d018e89d78a820891bd794fc 265 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 27 262 3.8E-57 T 12-10-2018 MIM_c40330 9a24c010d018e89d78a820891bd794fc 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 207 5.1E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c40330 9a24c010d018e89d78a820891bd794fc 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 22 39 5.1E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c40330 9a24c010d018e89d78a820891bd794fc 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 5.1E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c40330 9a24c010d018e89d78a820891bd794fc 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 5.1E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c40330 9a24c010d018e89d78a820891bd794fc 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 5.1E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c40330 9a24c010d018e89d78a820891bd794fc 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 188 5.1E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c40330 9a24c010d018e89d78a820891bd794fc 265 SUPERFAMILY SSF51735 19 263 2.83E-75 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c36530 43e70f93ec3d0af0e7ebcd3ef6e97873 268 SUPERFAMILY SSF46785 11 80 1.26E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c36530 43e70f93ec3d0af0e7ebcd3ef6e97873 268 Gene3D G3DSA:3.30.450.40 76 261 5.9E-44 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c36530 43e70f93ec3d0af0e7ebcd3ef6e97873 268 Pfam PF01614 Bacterial transcriptional regulator 127 249 6.7E-27 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal MIM_c36530 43e70f93ec3d0af0e7ebcd3ef6e97873 268 Pfam PF09339 IclR helix-turn-helix domain 12 59 3.4E-10 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c36530 43e70f93ec3d0af0e7ebcd3ef6e97873 268 Gene3D G3DSA:1.10.10.10 11 68 1.7E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c36530 43e70f93ec3d0af0e7ebcd3ef6e97873 268 SMART SM00346 11 97 0.0038 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c36530 43e70f93ec3d0af0e7ebcd3ef6e97873 268 SUPERFAMILY SSF55781 79 253 3.73E-41 T 12-10-2018 MIM_c05390 4d0a2cf5f0b945e5ddb68899d59d0737 231 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 36 50 - T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MIM_c05390 4d0a2cf5f0b945e5ddb68899d59d0737 231 Gene3D G3DSA:3.20.20.70 7 227 4.1E-82 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c05390 4d0a2cf5f0b945e5ddb68899d59d0737 231 PIRSF PIRSF001461 4 231 4.0E-103 T 12-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MIM_c05390 4d0a2cf5f0b945e5ddb68899d59d0737 231 SUPERFAMILY SSF51366 7 224 1.2E-74 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MIM_c05390 4d0a2cf5f0b945e5ddb68899d59d0737 231 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 138 160 - T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MIM_c05390 4d0a2cf5f0b945e5ddb68899d59d0737 231 Pfam PF00834 Ribulose-phosphate 3 epimerase family 9 209 2.4E-88 T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MIM_c05390 4d0a2cf5f0b945e5ddb68899d59d0737 231 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 9 222 3.0E-96 T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MIM_c06280 fa0a254b359f4c1f789ed15ee051c790 332 Gene3D G3DSA:3.40.190.150 39 322 2.5E-101 T 12-10-2018 MIM_c06280 fa0a254b359f4c1f789ed15ee051c790 332 Gene3D G3DSA:3.40.190.10 134 257 2.5E-101 T 12-10-2018 MIM_c06280 fa0a254b359f4c1f789ed15ee051c790 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 327 7.6E-78 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c06280 fa0a254b359f4c1f789ed15ee051c790 332 PIRSF PIRSF017082 2 332 2.2E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c06280 fa0a254b359f4c1f789ed15ee051c790 332 SUPERFAMILY SSF53850 108 283 3.8E-10 T 12-10-2018 MIM_c31490 2ed4f386cf97ed4516ad591d0edfc1fc 448 Gene3D G3DSA:3.40.640.10 69 351 3.8E-154 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c31490 2ed4f386cf97ed4516ad591d0edfc1fc 448 Gene3D G3DSA:3.90.1150.10 33 440 3.8E-154 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c31490 2ed4f386cf97ed4516ad591d0edfc1fc 448 SUPERFAMILY SSF53383 19 445 1.46E-115 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c31490 2ed4f386cf97ed4516ad591d0edfc1fc 448 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 256 293 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MIM_c31490 2ed4f386cf97ed4516ad591d0edfc1fc 448 PIRSF PIRSF000521 185 447 8.8E-15 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MIM_c31490 2ed4f386cf97ed4516ad591d0edfc1fc 448 PIRSF PIRSF000521 36 147 2.2E-6 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MIM_c31490 2ed4f386cf97ed4516ad591d0edfc1fc 448 Pfam PF00202 Aminotransferase class-III 35 442 3.3E-84 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MIM_c14530 e7742319d30ffb5105376fda3c4cecaf 129 SUPERFAMILY SSF51182 14 115 1.65E-25 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c14530 e7742319d30ffb5105376fda3c4cecaf 129 Pfam PF07883 Cupin domain 32 101 9.8E-22 T 12-10-2018 IPR013096 Cupin 2, conserved barrel MIM_c14530 e7742319d30ffb5105376fda3c4cecaf 129 Gene3D G3DSA:2.60.120.10 7 125 9.8E-40 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c39330 f4fe9a0fe52e946bb17f299a0f94ab0a 257 SUPERFAMILY SSF52540 4 246 3.66E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c39330 f4fe9a0fe52e946bb17f299a0f94ab0a 257 Gene3D G3DSA:3.40.50.300 2 247 3.3E-56 T 12-10-2018 MIM_c39330 f4fe9a0fe52e946bb17f299a0f94ab0a 257 Pfam PF00005 ABC transporter 22 177 5.0E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c39330 f4fe9a0fe52e946bb17f299a0f94ab0a 257 SMART SM00382 30 224 3.2E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c39330 f4fe9a0fe52e946bb17f299a0f94ab0a 257 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 246 1.5E-6 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal MIM_c34740 36aa6946e5833d1dc442d9183e8f67f2 265 SUPERFAMILY SSF46785 17 91 3.69E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c34740 36aa6946e5833d1dc442d9183e8f67f2 265 Gene3D G3DSA:1.10.10.10 15 89 1.2E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c34740 36aa6946e5833d1dc442d9183e8f67f2 265 Pfam PF09339 IclR helix-turn-helix domain 18 70 6.4E-12 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c34740 36aa6946e5833d1dc442d9183e8f67f2 265 Gene3D G3DSA:3.30.450.40 90 262 8.1E-31 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c34740 36aa6946e5833d1dc442d9183e8f67f2 265 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 29 39 - T 12-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 MIM_c34740 36aa6946e5833d1dc442d9183e8f67f2 265 SUPERFAMILY SSF55781 84 259 3.79E-33 T 12-10-2018 MIM_c34740 36aa6946e5833d1dc442d9183e8f67f2 265 Pfam PF01614 Bacterial transcriptional regulator 140 258 2.8E-16 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal MIM_c34740 36aa6946e5833d1dc442d9183e8f67f2 265 SMART SM00346 16 107 4.2E-9 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c15380 3111214c610aba37739845e910d299e0 450 SUPERFAMILY SSF46626 332 432 1.27E-22 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c15380 3111214c610aba37739845e910d299e0 450 Pfam PF00034 Cytochrome c 46 144 5.0E-6 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c15380 3111214c610aba37739845e910d299e0 450 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 331 412 2.5E-8 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c15380 3111214c610aba37739845e910d299e0 450 Gene3D G3DSA:1.10.760.10 168 312 3.7E-7 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c15380 3111214c610aba37739845e910d299e0 450 Gene3D G3DSA:1.10.760.10 313 441 2.3E-30 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c15380 3111214c610aba37739845e910d299e0 450 PIRSF PIRSF000018 18 447 1.4E-141 T 12-10-2018 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 MIM_c15380 3111214c610aba37739845e910d299e0 450 SUPERFAMILY SSF46626 41 167 1.66E-20 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c15380 3111214c610aba37739845e910d299e0 450 SUPERFAMILY SSF46626 190 301 1.69E-15 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c15380 3111214c610aba37739845e910d299e0 450 Gene3D G3DSA:1.10.760.10 1 150 6.3E-12 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c09390 f4bd061f5397fca1496dcc0c101d7176 188 Gene3D G3DSA:3.40.50.2300 2 125 1.7E-8 T 12-10-2018 MIM_c09390 f4bd061f5397fca1496dcc0c101d7176 188 Pfam PF03861 ANTAR domain 130 182 1.3E-18 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 MIM_c09390 f4bd061f5397fca1496dcc0c101d7176 188 Gene3D G3DSA:1.10.10.10 130 186 1.3E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c09390 f4bd061f5397fca1496dcc0c101d7176 188 SMART SM01012 127 182 1.8E-20 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 MIM_c09390 f4bd061f5397fca1496dcc0c101d7176 188 SUPERFAMILY SSF52172 1 182 6.19E-39 T 12-10-2018 IPR011006 CheY-like superfamily MIM_c09390 f4bd061f5397fca1496dcc0c101d7176 188 PIRSF PIRSF036382 1 188 1.3E-49 T 12-10-2018 IPR008327 Signal transduction response regulator, antiterminator MIM_c38290 e96369548f1a5bf1c0eeaed1901f0e8c 334 SUPERFAMILY SSF54637 236 332 8.51E-12 T 12-10-2018 IPR029069 HotDog domain superfamily MIM_c38290 e96369548f1a5bf1c0eeaed1901f0e8c 334 Pfam PF03061 Thioesterase superfamily 273 324 1.2E-5 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MIM_c38290 e96369548f1a5bf1c0eeaed1901f0e8c 334 Gene3D G3DSA:3.10.129.10 44 166 2.3E-6 T 12-10-2018 MIM_c38290 e96369548f1a5bf1c0eeaed1901f0e8c 334 Gene3D G3DSA:3.10.129.10 186 334 2.3E-13 T 12-10-2018 MIM_c17350 31eff44054b01da42323d0864022fb19 385 Gene3D G3DSA:3.20.20.120 134 375 1.9E-84 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MIM_c17350 31eff44054b01da42323d0864022fb19 385 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 47 140 4.9E-14 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain MIM_c17350 31eff44054b01da42323d0864022fb19 385 SUPERFAMILY SSF51604 128 383 7.34E-55 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MIM_c17350 31eff44054b01da42323d0864022fb19 385 Gene3D G3DSA:3.30.390.10 46 379 1.9E-84 T 12-10-2018 IPR029017 Enolase-like, N-terminal MIM_c17350 31eff44054b01da42323d0864022fb19 385 Pfam PF13378 Enolase C-terminal domain-like 166 376 3.8E-42 T 12-10-2018 IPR029065 Enolase C-terminal domain-like MIM_c17350 31eff44054b01da42323d0864022fb19 385 SMART SM00922 164 264 4.0E-16 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MIM_c17350 31eff44054b01da42323d0864022fb19 385 SUPERFAMILY SSF54826 43 144 9.64E-22 T 12-10-2018 MIM_c11420 e890e0e497f8d262e02a9f17f0d4dcd0 83 Gene3D G3DSA:3.40.1620.10 1 37 1.1E-6 T 12-10-2018 MIM_c11420 e890e0e497f8d262e02a9f17f0d4dcd0 83 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 67 3.6E-11 T 12-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM MIM_c11420 e890e0e497f8d262e02a9f17f0d4dcd0 83 SUPERFAMILY SSF143120 1 61 1.83E-11 T 12-10-2018 IPR036165 YefM-like superfamily MIM_c11420 e890e0e497f8d262e02a9f17f0d4dcd0 83 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 57 1.0E-5 T 12-10-2018 MIM_c04490 a6e7d4231e0b2281f3657600bdd6af60 470 Gene3D G3DSA:1.20.1250.20 271 461 2.2E-14 T 12-10-2018 MIM_c04490 a6e7d4231e0b2281f3657600bdd6af60 470 Pfam PF07690 Major Facilitator Superfamily 36 423 4.1E-40 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c04490 a6e7d4231e0b2281f3657600bdd6af60 470 SUPERFAMILY SSF103473 3 458 1.96E-57 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c04490 a6e7d4231e0b2281f3657600bdd6af60 470 Gene3D G3DSA:1.20.1720.10 35 258 1.1E-39 T 12-10-2018 MIM_c14690 d20f7bdd5b6085426a2e10c3118a3968 189 Pfam PF04390 Lipopolysaccharide-assembly 51 166 5.1E-8 T 12-10-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 MIM_c14690 d20f7bdd5b6085426a2e10c3118a3968 189 Gene3D G3DSA:3.30.160.150 40 174 7.3E-37 T 12-10-2018 MIM_c14690 d20f7bdd5b6085426a2e10c3118a3968 189 Hamap MF_01186 LPS-assembly lipoprotein LptE [lptE]. 12 171 22.107 T 12-10-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 MIM_c00440 b59fc27e504e4847e931a94e40d7c171 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 2.4E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MIM_c00440 b59fc27e504e4847e931a94e40d7c171 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 2.4E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MIM_c00440 b59fc27e504e4847e931a94e40d7c171 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 2.4E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MIM_c00440 b59fc27e504e4847e931a94e40d7c171 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 32 43 2.4E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MIM_c00440 b59fc27e504e4847e931a94e40d7c171 114 Pfam PF12840 Helix-turn-helix domain 10 69 3.9E-10 T 12-10-2018 MIM_c00440 b59fc27e504e4847e931a94e40d7c171 114 SUPERFAMILY SSF46785 1 102 1.99E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c00440 b59fc27e504e4847e931a94e40d7c171 114 Gene3D G3DSA:1.10.10.10 2 112 4.7E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c00440 b59fc27e504e4847e931a94e40d7c171 114 SMART SM00418 11 89 5.6E-15 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MIM_c34220 6e339e411810efa206c31ae50f711dc1 510 Gene3D G3DSA:3.40.50.300 92 307 9.1E-10 T 12-10-2018 MIM_c34220 6e339e411810efa206c31ae50f711dc1 510 SMART SM00382 148 294 0.0067 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c34220 6e339e411810efa206c31ae50f711dc1 510 Pfam PF09848 Uncharacterized conserved protein (DUF2075) 150 492 8.9E-97 T 12-10-2018 IPR018647 Domain of unknown function DUF2075 MIM_c34220 6e339e411810efa206c31ae50f711dc1 510 SUPERFAMILY SSF52540 122 268 8.13E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c35610 b909a53d566e5e53647bd73e1e006842 495 Gene3D G3DSA:3.10.310.50 22 173 1.1E-36 T 12-10-2018 MIM_c35610 b909a53d566e5e53647bd73e1e006842 495 Pfam PF04536 TPM domain 43 165 1.7E-27 T 12-10-2018 IPR007621 TPM domain MIM_c03760 21122a5a86aa636a2393eb5dddef677a 440 Gene3D G3DSA:3.90.420.10 75 317 1.5E-64 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 MIM_c03760 21122a5a86aa636a2393eb5dddef677a 440 SUPERFAMILY SSF81296 322 432 1.82E-23 T 12-10-2018 IPR014756 Immunoglobulin E-set MIM_c03760 21122a5a86aa636a2393eb5dddef677a 440 Gene3D G3DSA:2.60.40.650 323 437 1.5E-30 T 12-10-2018 MIM_c03760 21122a5a86aa636a2393eb5dddef677a 440 PRINTS PR00407 Eukaryotic molybdopterin domain signature 190 205 6.0E-14 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 MIM_c03760 21122a5a86aa636a2393eb5dddef677a 440 PRINTS PR00407 Eukaryotic molybdopterin domain signature 262 275 6.0E-14 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 MIM_c03760 21122a5a86aa636a2393eb5dddef677a 440 PRINTS PR00407 Eukaryotic molybdopterin domain signature 245 261 6.0E-14 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 MIM_c03760 21122a5a86aa636a2393eb5dddef677a 440 PRINTS PR00407 Eukaryotic molybdopterin domain signature 403 415 6.0E-14 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 MIM_c03760 21122a5a86aa636a2393eb5dddef677a 440 PRINTS PR00407 Eukaryotic molybdopterin domain signature 278 291 6.0E-14 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 MIM_c03760 21122a5a86aa636a2393eb5dddef677a 440 PRINTS PR00407 Eukaryotic molybdopterin domain signature 111 127 6.0E-14 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 MIM_c03760 21122a5a86aa636a2393eb5dddef677a 440 PRINTS PR00407 Eukaryotic molybdopterin domain signature 358 370 6.0E-14 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 MIM_c03760 21122a5a86aa636a2393eb5dddef677a 440 Pfam PF00174 Oxidoreductase molybdopterin binding domain 134 298 1.9E-38 T 12-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 MIM_c03760 21122a5a86aa636a2393eb5dddef677a 440 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 320 427 5.5E-8 T 12-10-2018 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 MIM_c03760 21122a5a86aa636a2393eb5dddef677a 440 SUPERFAMILY SSF56524 90 311 1.03E-45 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 MIM_c03190 0d2e8483639588025bd30c7630ef88de 273 SUPERFAMILY SSF53335 38 171 9.67E-14 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c03190 0d2e8483639588025bd30c7630ef88de 273 Pfam PF13679 Methyltransferase domain 34 174 4.2E-44 T 12-10-2018 IPR025714 Methyltransferase domain MIM_c03190 0d2e8483639588025bd30c7630ef88de 273 Gene3D G3DSA:3.40.50.150 38 184 1.9E-5 T 12-10-2018 MIM_c07420 4222e1690cd3a74a70a937bb07c43e56 251 Pfam PF00899 ThiF family 9 243 8.2E-64 T 12-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MIM_c07420 4222e1690cd3a74a70a937bb07c43e56 251 SUPERFAMILY SSF69572 2 246 3.53E-85 T 12-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 MIM_c07420 4222e1690cd3a74a70a937bb07c43e56 251 Gene3D G3DSA:3.40.50.720 1 251 5.8E-90 T 12-10-2018 MIM_c15810 f74eedbace34b1b067b95fc3dcbfcb99 262 SUPERFAMILY SSF53448 4 256 9.3E-53 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MIM_c15810 f74eedbace34b1b067b95fc3dcbfcb99 262 Pfam PF02348 Cytidylyltransferase 5 231 1.0E-49 T 12-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 MIM_c15810 f74eedbace34b1b067b95fc3dcbfcb99 262 Gene3D G3DSA:3.90.550.10 2 258 4.8E-86 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MIM_c15810 f74eedbace34b1b067b95fc3dcbfcb99 262 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 4 252 3.4E-80 T 12-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 MIM_c15810 f74eedbace34b1b067b95fc3dcbfcb99 262 Hamap MF_00057 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase [kdsB]. 2 259 39.641 T 12-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 MIM_c25180 0c01e27d564768db415c909e29fd8521 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 1.8E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c25180 0c01e27d564768db415c909e29fd8521 303 SUPERFAMILY SSF53850 90 297 1.81E-46 T 12-10-2018 MIM_c25180 0c01e27d564768db415c909e29fd8521 303 Gene3D G3DSA:1.10.10.10 5 91 2.5E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c25180 0c01e27d564768db415c909e29fd8521 303 SUPERFAMILY SSF46785 6 114 2.66E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c25180 0c01e27d564768db415c909e29fd8521 303 Gene3D G3DSA:3.40.190.10 93 293 3.1E-65 T 12-10-2018 MIM_c25180 0c01e27d564768db415c909e29fd8521 303 Gene3D G3DSA:3.40.190.10 166 266 3.1E-65 T 12-10-2018 MIM_c25180 0c01e27d564768db415c909e29fd8521 303 Pfam PF03466 LysR substrate binding domain 90 295 2.4E-44 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c39110 b3cd817304f6ece5e85d306b223b26a2 392 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 193 379 2.6E-10 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c39110 b3cd817304f6ece5e85d306b223b26a2 392 Gene3D G3DSA:1.10.3720.10 143 389 4.4E-50 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c39110 b3cd817304f6ece5e85d306b223b26a2 392 SUPERFAMILY SSF161098 167 380 4.19E-46 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c23040 2f3cfb9d4dd5fbdf0d0fa464cce3ce37 412 Gene3D G3DSA:1.10.3860.10 7 403 9.8E-72 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MIM_c23040 2f3cfb9d4dd5fbdf0d0fa464cce3ce37 412 PRINTS PR00173 Glutamate-aspartate symporter signature 13 33 1.7E-13 T 12-10-2018 MIM_c23040 2f3cfb9d4dd5fbdf0d0fa464cce3ce37 412 PRINTS PR00173 Glutamate-aspartate symporter signature 287 313 1.7E-13 T 12-10-2018 MIM_c23040 2f3cfb9d4dd5fbdf0d0fa464cce3ce37 412 PRINTS PR00173 Glutamate-aspartate symporter signature 185 204 1.7E-13 T 12-10-2018 MIM_c23040 2f3cfb9d4dd5fbdf0d0fa464cce3ce37 412 PRINTS PR00173 Glutamate-aspartate symporter signature 322 341 1.7E-13 T 12-10-2018 MIM_c23040 2f3cfb9d4dd5fbdf0d0fa464cce3ce37 412 Hamap MF_01582 Serine/threonine transporter SstT [sstT]. 3 404 35.067 T 12-10-2018 IPR023025 Serine/threonine transporter SstT GO:0015293|GO:0015826|GO:0032329 MIM_c23040 2f3cfb9d4dd5fbdf0d0fa464cce3ce37 412 Pfam PF00375 Sodium:dicarboxylate symporter family 15 398 8.8E-67 T 12-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MIM_c23040 2f3cfb9d4dd5fbdf0d0fa464cce3ce37 412 SUPERFAMILY SSF118215 15 398 9.81E-94 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MIM_c05590 0c58e66c73ea8ff686fea9e795df73d8 329 SUPERFAMILY SSF53697 13 326 3.34E-63 T 12-10-2018 MIM_c05590 0c58e66c73ea8ff686fea9e795df73d8 329 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 50 319 7.6E-100 T 12-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 MIM_c05590 0c58e66c73ea8ff686fea9e795df73d8 329 Gene3D G3DSA:3.10.580.10 202 326 1.3E-43 T 12-10-2018 MIM_c05590 0c58e66c73ea8ff686fea9e795df73d8 329 Pfam PF01380 SIS domain 45 177 7.0E-29 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MIM_c05590 0c58e66c73ea8ff686fea9e795df73d8 329 Pfam PF00571 CBS domain 206 263 2.7E-6 T 12-10-2018 IPR000644 CBS domain MIM_c05590 0c58e66c73ea8ff686fea9e795df73d8 329 Pfam PF00571 CBS domain 273 326 1.4E-5 T 12-10-2018 IPR000644 CBS domain MIM_c05590 0c58e66c73ea8ff686fea9e795df73d8 329 PIRSF PIRSF004692 1 329 2.5E-128 T 12-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 MIM_c05590 0c58e66c73ea8ff686fea9e795df73d8 329 Gene3D G3DSA:3.40.50.10490 7 201 2.1E-64 T 12-10-2018 MIM_c29590 c70b4a0d48aa50dcb81f06d50404aa3b 269 Pfam PF08543 Phosphomethylpyrimidine kinase 16 259 2.9E-27 T 12-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 MIM_c29590 c70b4a0d48aa50dcb81f06d50404aa3b 269 SUPERFAMILY SSF53613 6 261 1.85E-26 T 12-10-2018 IPR029056 Ribokinase-like MIM_c29590 c70b4a0d48aa50dcb81f06d50404aa3b 269 Gene3D G3DSA:3.40.1190.20 5 266 5.0E-34 T 12-10-2018 IPR029056 Ribokinase-like MIM_c11720 324558305ee05be58d3f20fec02f0422 307 Gene3D G3DSA:1.10.10.10 1 87 1.4E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c11720 324558305ee05be58d3f20fec02f0422 307 Pfam PF03466 LysR substrate binding domain 85 290 1.1E-48 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c11720 324558305ee05be58d3f20fec02f0422 307 SUPERFAMILY SSF53850 86 293 2.33E-50 T 12-10-2018 MIM_c11720 324558305ee05be58d3f20fec02f0422 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 5.6E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c11720 324558305ee05be58d3f20fec02f0422 307 SUPERFAMILY SSF46785 3 84 1.69E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c11720 324558305ee05be58d3f20fec02f0422 307 Gene3D G3DSA:3.40.190.10 160 261 7.6E-70 T 12-10-2018 MIM_c11720 324558305ee05be58d3f20fec02f0422 307 Gene3D G3DSA:3.40.190.10 88 287 7.6E-70 T 12-10-2018 MIM_c19250 0d35614784dc57f2eb98ff49558e3259 162 Pfam PF02674 Colicin V production protein 4 142 1.3E-32 T 12-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 MIM_c29310 daedf25dc0c0ccae1dfa20a4dae58e4d 366 PIRSF PIRSF039026 1 359 1.3E-121 T 12-10-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like MIM_c29310 daedf25dc0c0ccae1dfa20a4dae58e4d 366 Gene3D G3DSA:3.40.190.10 154 324 2.1E-124 T 12-10-2018 MIM_c29310 daedf25dc0c0ccae1dfa20a4dae58e4d 366 Gene3D G3DSA:3.40.190.170 34 338 2.1E-124 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily MIM_c29310 daedf25dc0c0ccae1dfa20a4dae58e4d 366 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 54 322 1.1E-56 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 MIM_c24010 7c6d5d56356077c4710117e5a604bfcc 328 Gene3D G3DSA:3.90.420.10 66 328 1.6E-100 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 MIM_c24010 7c6d5d56356077c4710117e5a604bfcc 328 Pfam PF00174 Oxidoreductase molybdopterin binding domain 108 263 1.7E-30 T 12-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 MIM_c24010 7c6d5d56356077c4710117e5a604bfcc 328 Hamap MF_01206 Protein-methionine-sulfoxide reductase catalytic subunit MsrP [msrP]. 8 328 52.815 T 12-10-2018 IPR022867 Protein-methionine-sulfoxide reductase subunit MsrP GO:0016667|GO:0030091|GO:0043546|GO:0055114 MIM_c24010 7c6d5d56356077c4710117e5a604bfcc 328 SUPERFAMILY SSF56524 76 324 8.89E-87 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 MIM_c19820 512c40353a9d76bd51aad7336d0095a8 242 Gene3D G3DSA:3.40.50.300 1 241 1.6E-81 T 12-10-2018 MIM_c19820 512c40353a9d76bd51aad7336d0095a8 242 SMART SM00382 24 210 1.4E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c19820 512c40353a9d76bd51aad7336d0095a8 242 SUPERFAMILY SSF52540 3 232 5.08E-78 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c19820 512c40353a9d76bd51aad7336d0095a8 242 PIRSF PIRSF039085 1 238 9.0E-112 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MIM_c19820 512c40353a9d76bd51aad7336d0095a8 242 Pfam PF00005 ABC transporter 15 162 4.4E-38 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c19820 512c40353a9d76bd51aad7336d0095a8 242 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c01440 51f15e65745873951e9b3f6a52158035 197 Gene3D G3DSA:1.25.40.20 2 197 1.7E-54 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily MIM_c01440 51f15e65745873951e9b3f6a52158035 197 Pfam PF12796 Ankyrin repeats (3 copies) 4 65 3.0E-7 T 12-10-2018 IPR020683 Ankyrin repeat-containing domain MIM_c01440 51f15e65745873951e9b3f6a52158035 197 SUPERFAMILY SSF48403 4 196 5.67E-48 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily MIM_c01440 51f15e65745873951e9b3f6a52158035 197 Pfam PF00023 Ankyrin repeat 134 169 0.0092 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 MIM_c01440 51f15e65745873951e9b3f6a52158035 197 Pfam PF13637 Ankyrin repeats (many copies) 70 121 3.2E-9 T 12-10-2018 MIM_c01440 51f15e65745873951e9b3f6a52158035 197 SMART SM00248 100 129 2.2 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 MIM_c01440 51f15e65745873951e9b3f6a52158035 197 SMART SM00248 1 30 51.0 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 MIM_c01440 51f15e65745873951e9b3f6a52158035 197 SMART SM00248 67 96 170.0 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 MIM_c01440 51f15e65745873951e9b3f6a52158035 197 SMART SM00248 133 167 4.7 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 MIM_c01440 51f15e65745873951e9b3f6a52158035 197 SMART SM00248 34 63 0.43 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 MIM_c09930 1e73ec71d2087d97f81342ca65b169c7 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 248 2.7E-68 T 12-10-2018 MIM_c09930 1e73ec71d2087d97f81342ca65b169c7 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.8E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c09930 1e73ec71d2087d97f81342ca65b169c7 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.8E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c09930 1e73ec71d2087d97f81342ca65b169c7 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 1.8E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c09930 1e73ec71d2087d97f81342ca65b169c7 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.8E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c09930 1e73ec71d2087d97f81342ca65b169c7 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.8E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c09930 1e73ec71d2087d97f81342ca65b169c7 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.8E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c09930 1e73ec71d2087d97f81342ca65b169c7 250 Gene3D G3DSA:3.40.50.720 2 250 4.4E-83 T 12-10-2018 MIM_c09930 1e73ec71d2087d97f81342ca65b169c7 250 SUPERFAMILY SSF51735 6 250 2.48E-83 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c09930 1e73ec71d2087d97f81342ca65b169c7 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.1E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c09930 1e73ec71d2087d97f81342ca65b169c7 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.1E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c09930 1e73ec71d2087d97f81342ca65b169c7 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.1E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c09930 1e73ec71d2087d97f81342ca65b169c7 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c34820 41047a0dc72912458d733b5baf32fa55 109 SUPERFAMILY SSF160113 8 55 2.22E-14 T 12-10-2018 IPR036913 YegP-like superfamily MIM_c34820 41047a0dc72912458d733b5baf32fa55 109 Gene3D G3DSA:2.30.29.80 1 109 2.2E-41 T 12-10-2018 MIM_c34820 41047a0dc72912458d733b5baf32fa55 109 SUPERFAMILY SSF160113 60 107 7.46E-14 T 12-10-2018 IPR036913 YegP-like superfamily MIM_c34820 41047a0dc72912458d733b5baf32fa55 109 Pfam PF07411 Domain of unknown function (DUF1508) 60 107 2.2E-19 T 12-10-2018 IPR010879 Domain of unknown function DUF1508 MIM_c34820 41047a0dc72912458d733b5baf32fa55 109 Pfam PF07411 Domain of unknown function (DUF1508) 11 55 3.6E-18 T 12-10-2018 IPR010879 Domain of unknown function DUF1508 MIM_c36380 180afdcba500ee7be4592935ebcd359e 407 Gene3D G3DSA:1.10.490.10 8 150 3.3E-46 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 MIM_c36380 180afdcba500ee7be4592935ebcd359e 407 Pfam PF00042 Globin 15 109 3.3E-7 T 12-10-2018 IPR000971 Globin GO:0020037 MIM_c36380 180afdcba500ee7be4592935ebcd359e 407 SUPERFAMILY SSF63380 155 258 1.15E-26 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MIM_c36380 180afdcba500ee7be4592935ebcd359e 407 Gene3D G3DSA:2.40.30.10 157 261 1.8E-31 T 12-10-2018 MIM_c36380 180afdcba500ee7be4592935ebcd359e 407 Pfam PF00970 Oxidoreductase FAD-binding domain 164 261 7.5E-5 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 MIM_c36380 180afdcba500ee7be4592935ebcd359e 407 PRINTS PR00409 Phthalate dioxygenase reductase family signature 234 248 6.4E-10 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MIM_c36380 180afdcba500ee7be4592935ebcd359e 407 PRINTS PR00409 Phthalate dioxygenase reductase family signature 271 290 6.4E-10 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MIM_c36380 180afdcba500ee7be4592935ebcd359e 407 Pfam PF00175 Oxidoreductase NAD-binding domain 272 378 9.4E-13 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MIM_c36380 180afdcba500ee7be4592935ebcd359e 407 Gene3D G3DSA:3.40.50.80 265 403 2.1E-31 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MIM_c36380 180afdcba500ee7be4592935ebcd359e 407 SUPERFAMILY SSF46458 5 143 2.33E-33 T 12-10-2018 IPR009050 Globin-like superfamily MIM_c36380 180afdcba500ee7be4592935ebcd359e 407 SUPERFAMILY SSF52343 262 401 6.81E-34 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MIM_c29320 e59c8680b329bcbeb7877b3e8ac5dd26 455 Gene3D G3DSA:3.30.2290.10 4 237 1.4E-81 T 12-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal MIM_c29320 e59c8680b329bcbeb7877b3e8ac5dd26 455 Pfam PF01523 Putative modulator of DNA gyrase 39 328 7.9E-59 T 12-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 MIM_c29320 e59c8680b329bcbeb7877b3e8ac5dd26 455 SUPERFAMILY SSF111283 16 454 1.05E-119 T 12-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 MIM_c24060 adb15f334ff7c478c70362e387a60edc 573 SUPERFAMILY SSF51905 34 409 3.35E-52 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c24060 adb15f334ff7c478c70362e387a60edc 573 Pfam PF01494 FAD binding domain 33 373 5.6E-62 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 MIM_c24060 adb15f334ff7c478c70362e387a60edc 573 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 181 196 1.9E-31 T 12-10-2018 MIM_c24060 adb15f334ff7c478c70362e387a60edc 573 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 33 55 1.9E-31 T 12-10-2018 MIM_c24060 adb15f334ff7c478c70362e387a60edc 573 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 310 325 1.9E-31 T 12-10-2018 MIM_c24060 adb15f334ff7c478c70362e387a60edc 573 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 325 341 1.9E-31 T 12-10-2018 MIM_c24060 adb15f334ff7c478c70362e387a60edc 573 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 343 361 1.9E-31 T 12-10-2018 MIM_c24060 adb15f334ff7c478c70362e387a60edc 573 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 361 377 1.9E-31 T 12-10-2018 MIM_c24060 adb15f334ff7c478c70362e387a60edc 573 Gene3D G3DSA:3.40.30.120 416 562 2.7E-6 T 12-10-2018 MIM_c24060 adb15f334ff7c478c70362e387a60edc 573 Gene3D G3DSA:3.50.50.60 34 373 2.1E-82 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c24060 adb15f334ff7c478c70362e387a60edc 573 Gene3D G3DSA:3.30.70.2450 210 299 2.1E-82 T 12-10-2018 MIM_c16620 2f4934447d8d9efc6e2108cdc777ae27 340 SMART SM00046 35 158 3.8E-4 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 MIM_c16620 2f4934447d8d9efc6e2108cdc777ae27 340 Gene3D G3DSA:3.40.50.10330 31 158 4.2E-22 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 MIM_c16620 2f4934447d8d9efc6e2108cdc777ae27 340 Gene3D G3DSA:2.60.200.40 159 321 1.1E-14 T 12-10-2018 MIM_c16620 2f4934447d8d9efc6e2108cdc777ae27 340 Pfam PF00781 Diacylglycerol kinase catalytic domain 36 158 2.3E-22 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 MIM_c16620 2f4934447d8d9efc6e2108cdc777ae27 340 SUPERFAMILY SSF111331 34 332 1.63E-47 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily MIM_c37060 fefc9abf8729cb17fb06057f6d9f4dc9 424 SUPERFAMILY SSF69075 319 419 7.19E-27 T 12-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MIM_c37060 fefc9abf8729cb17fb06057f6d9f4dc9 424 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 5 411 1.1E-126 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MIM_c37060 fefc9abf8729cb17fb06057f6d9f4dc9 424 Gene3D G3DSA:3.30.460.30 4 160 3.5E-53 T 12-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MIM_c37060 fefc9abf8729cb17fb06057f6d9f4dc9 424 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 174 306 1.1E-42 T 12-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase MIM_c37060 fefc9abf8729cb17fb06057f6d9f4dc9 424 SUPERFAMILY SSF69742 5 160 4.45E-43 T 12-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MIM_c37060 fefc9abf8729cb17fb06057f6d9f4dc9 424 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 4 417 28.945 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MIM_c37060 fefc9abf8729cb17fb06057f6d9f4dc9 424 SUPERFAMILY SSF51735 165 316 7.64E-31 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c37060 fefc9abf8729cb17fb06057f6d9f4dc9 424 PIRSF PIRSF000445 3 424 3.9E-147 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MIM_c37060 fefc9abf8729cb17fb06057f6d9f4dc9 424 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 101 124 - T 12-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MIM_c37060 fefc9abf8729cb17fb06057f6d9f4dc9 424 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 322 417 1.0E-27 T 12-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MIM_c37060 fefc9abf8729cb17fb06057f6d9f4dc9 424 Gene3D G3DSA:3.40.50.720 163 314 1.8E-41 T 12-10-2018 MIM_c37060 fefc9abf8729cb17fb06057f6d9f4dc9 424 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 9 158 1.7E-46 T 12-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MIM_c25060 fc3642450e3e499918471254b45ee8ed 170 SUPERFAMILY SSF52833 2 169 1.79E-27 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c25060 fc3642450e3e499918471254b45ee8ed 170 Pfam PF01323 DSBA-like thioredoxin domain 3 166 4.0E-33 T 12-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 MIM_c25060 fc3642450e3e499918471254b45ee8ed 170 PIRSF PIRSF006386 1 170 5.3E-42 T 12-10-2018 IPR014440 HCCA isomerase/glutathione S-transferase kappa Reactome: R-HSA-156590|Reactome: R-HSA-9033241 MIM_c25060 fc3642450e3e499918471254b45ee8ed 170 Gene3D G3DSA:3.40.30.10 1 169 1.0E-42 T 12-10-2018 MIM_c02780 d6bdcbfb1d06295c4674cf6e3a7ced20 236 Pfam PF13417 Glutathione S-transferase, N-terminal domain 14 82 2.0E-13 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MIM_c02780 d6bdcbfb1d06295c4674cf6e3a7ced20 236 Pfam PF13410 Glutathione S-transferase, C-terminal domain 154 194 9.4E-6 T 12-10-2018 MIM_c02780 d6bdcbfb1d06295c4674cf6e3a7ced20 236 Gene3D G3DSA:1.20.1050.10 90 219 1.3E-14 T 12-10-2018 MIM_c02780 d6bdcbfb1d06295c4674cf6e3a7ced20 236 SUPERFAMILY SSF52833 16 102 1.7E-17 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c02780 d6bdcbfb1d06295c4674cf6e3a7ced20 236 SUPERFAMILY SSF47616 74 220 3.48E-10 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MIM_c02780 d6bdcbfb1d06295c4674cf6e3a7ced20 236 Gene3D G3DSA:3.40.30.10 8 84 1.9E-16 T 12-10-2018 MIM_c22650 0abb8304b9da30501d9b96bb06158fda 253 SUPERFAMILY SSF52540 16 244 1.25E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c22650 0abb8304b9da30501d9b96bb06158fda 253 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c22650 0abb8304b9da30501d9b96bb06158fda 253 SMART SM00382 42 226 2.6E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c22650 0abb8304b9da30501d9b96bb06158fda 253 Pfam PF00005 ABC transporter 35 181 3.4E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c22650 0abb8304b9da30501d9b96bb06158fda 253 Gene3D G3DSA:3.40.50.300 13 252 2.6E-57 T 12-10-2018 MIM_c24460 cc4723f3108c141a974caed01bbc4d65 493 Pfam PF00361 Proton-conducting membrane transporter 126 427 6.2E-67 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24460 cc4723f3108c141a974caed01bbc4d65 493 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 9 478 6.8E-133 T 12-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 MIM_c24460 cc4723f3108c141a974caed01bbc4d65 493 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 5 480 17.985 T 12-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 MIM_c24460 cc4723f3108c141a974caed01bbc4d65 493 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 73 98 5.9E-6 T 12-10-2018 MIM_c24460 cc4723f3108c141a974caed01bbc4d65 493 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 217 238 5.9E-6 T 12-10-2018 MIM_c24460 cc4723f3108c141a974caed01bbc4d65 493 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 421 440 5.9E-6 T 12-10-2018 MIM_c13190 b880a467002881d7e5e9577a88139af9 483 SUPERFAMILY SSF103378 12 482 4.45E-164 T 12-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 MIM_c13190 b880a467002881d7e5e9577a88139af9 483 TIGRFAM TIGR02330 prpD: 2-methylcitrate dehydratase 13 483 2.2E-262 T 12-10-2018 IPR012705 2-methylcitrate dehydratase PrpD GO:0019629|GO:0047547|GO:0051537 KEGG: 00640+4.2.1.79 MIM_c13190 b880a467002881d7e5e9577a88139af9 483 Pfam PF03972 MmgE/PrpD family 19 466 2.7E-162 T 12-10-2018 IPR005656 MmgE/PrpD GO:0016829 MIM_c13190 b880a467002881d7e5e9577a88139af9 483 Gene3D G3DSA:1.10.4100.10 22 461 4.4E-206 T 12-10-2018 MIM_c13190 b880a467002881d7e5e9577a88139af9 483 Gene3D G3DSA:3.30.1330.120 285 426 4.4E-206 T 12-10-2018 MIM_c13800 d0fa7b565710efe0d1a59ed8c265edc2 435 SUPERFAMILY SSF100950 188 427 1.81E-54 T 12-10-2018 IPR037171 NagB/RpiA transferase-like MIM_c13800 d0fa7b565710efe0d1a59ed8c265edc2 435 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 273 425 1.9E-45 T 12-10-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain MIM_c13800 d0fa7b565710efe0d1a59ed8c265edc2 435 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 20 182 1.5E-5 T 12-10-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 MIM_c13800 d0fa7b565710efe0d1a59ed8c265edc2 435 Gene3D G3DSA:3.40.1080.20 292 434 3.0E-47 T 12-10-2018 IPR038460 Acetyl-CoA hydrolase/transferase, C-terminal domain superfamily MIM_c13800 d0fa7b565710efe0d1a59ed8c265edc2 435 Gene3D G3DSA:3.30.750.70 186 290 4.2E-29 T 12-10-2018 MIM_c13800 d0fa7b565710efe0d1a59ed8c265edc2 435 Gene3D G3DSA:3.40.1080.10 16 184 2.8E-31 T 12-10-2018 MIM_c13800 d0fa7b565710efe0d1a59ed8c265edc2 435 SUPERFAMILY SSF100950 24 223 7.32E-21 T 12-10-2018 IPR037171 NagB/RpiA transferase-like MIM_c28100 8a1ac05765d80c240046a3f0b6ba3a7c 355 Gene3D G3DSA:3.30.1370.60 75 315 5.4E-105 T 12-10-2018 MIM_c28100 8a1ac05765d80c240046a3f0b6ba3a7c 355 Pfam PF02615 Malate/L-lactate dehydrogenase 12 341 9.9E-110 T 12-10-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0016491|GO:0055114 MIM_c28100 8a1ac05765d80c240046a3f0b6ba3a7c 355 Gene3D G3DSA:1.10.1530.10 22 346 5.4E-105 T 12-10-2018 MIM_c28100 8a1ac05765d80c240046a3f0b6ba3a7c 355 SUPERFAMILY SSF89733 10 347 1.57E-103 T 12-10-2018 IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily GO:0016491|GO:0055114 MIM_c30070 97cc1a389ebed91f8c5050f71751629b 340 SUPERFAMILY SSF53850 26 256 1.53E-45 T 12-10-2018 MIM_c30070 97cc1a389ebed91f8c5050f71751629b 340 Gene3D G3DSA:3.40.190.10 122 228 4.4E-50 T 12-10-2018 MIM_c30070 97cc1a389ebed91f8c5050f71751629b 340 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 58 71 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site MIM_c30070 97cc1a389ebed91f8c5050f71751629b 340 SMART SM00062 35 265 4.0E-44 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c30070 97cc1a389ebed91f8c5050f71751629b 340 Gene3D G3DSA:3.40.190.10 30 245 4.4E-50 T 12-10-2018 MIM_c30070 97cc1a389ebed91f8c5050f71751629b 340 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 37 249 1.5E-28 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c03840 53a68946822e3ced3a3e394167b580a0 268 SUPERFAMILY SSF53850 28 258 3.32E-63 T 12-10-2018 MIM_c03840 53a68946822e3ced3a3e394167b580a0 268 SMART SM00062 30 259 5.3E-71 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c03840 53a68946822e3ced3a3e394167b580a0 268 Gene3D G3DSA:3.40.190.10 32 255 5.1E-74 T 12-10-2018 MIM_c03840 53a68946822e3ced3a3e394167b580a0 268 Gene3D G3DSA:3.40.190.10 116 216 5.1E-74 T 12-10-2018 MIM_c03840 53a68946822e3ced3a3e394167b580a0 268 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 31 257 2.0E-60 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c29860 99f18f1bcbadd2cf084953f952ee6801 118 Pfam PF00034 Cytochrome c 32 113 2.5E-7 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c29860 99f18f1bcbadd2cf084953f952ee6801 118 PRINTS PR00606 Class ID cytochrome C signature 75 88 4.0E-11 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 MIM_c29860 99f18f1bcbadd2cf084953f952ee6801 118 PRINTS PR00606 Class ID cytochrome C signature 90 100 4.0E-11 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 MIM_c29860 99f18f1bcbadd2cf084953f952ee6801 118 PRINTS PR00606 Class ID cytochrome C signature 36 49 4.0E-11 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 MIM_c29860 99f18f1bcbadd2cf084953f952ee6801 118 PRINTS PR00606 Class ID cytochrome C signature 102 112 4.0E-11 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 MIM_c29860 99f18f1bcbadd2cf084953f952ee6801 118 Gene3D G3DSA:1.10.760.10 34 114 6.1E-27 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c29860 99f18f1bcbadd2cf084953f952ee6801 118 SUPERFAMILY SSF46626 9 115 1.89E-17 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c06180 6d7d158422f93519a88a512c48c2f5d4 177 Pfam PF10634 Fe2+ transport protein 20 170 3.1E-70 T 12-10-2018 IPR018470 Periplasmic metal-binding protein Tp34-type MIM_c06180 6d7d158422f93519a88a512c48c2f5d4 177 PIRSF PIRSF017018 1 177 2.8E-82 T 12-10-2018 IPR018470 Periplasmic metal-binding protein Tp34-type MIM_c06180 6d7d158422f93519a88a512c48c2f5d4 177 Gene3D G3DSA:2.60.40.2480 19 177 1.6E-71 T 12-10-2018 IPR038482 Periplasmic metal-binding protein tp34-type superfamily MIM_c21880 4ee6cf696703b25c0b25a8289a640fe7 112 Gene3D G3DSA:3.30.70.120 1 112 5.1E-45 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MIM_c21880 4ee6cf696703b25c0b25a8289a640fe7 112 PRINTS PR00340 P-II protein signature 83 103 7.4E-44 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MIM_c21880 4ee6cf696703b25c0b25a8289a640fe7 112 PRINTS PR00340 P-II protein signature 23 41 7.4E-44 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MIM_c21880 4ee6cf696703b25c0b25a8289a640fe7 112 PRINTS PR00340 P-II protein signature 2 17 7.4E-44 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MIM_c21880 4ee6cf696703b25c0b25a8289a640fe7 112 PRINTS PR00340 P-II protein signature 52 75 7.4E-44 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MIM_c21880 4ee6cf696703b25c0b25a8289a640fe7 112 SUPERFAMILY SSF54913 2 112 2.19E-43 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta MIM_c21880 4ee6cf696703b25c0b25a8289a640fe7 112 SMART SM00938 4 105 2.8E-66 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MIM_c21880 4ee6cf696703b25c0b25a8289a640fe7 112 PIRSF PIRSF039144 1 112 3.2E-52 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MIM_c21880 4ee6cf696703b25c0b25a8289a640fe7 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 12-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 MIM_c21880 4ee6cf696703b25c0b25a8289a640fe7 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 5.9E-42 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MIM_c21880 4ee6cf696703b25c0b25a8289a640fe7 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 12-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 MIM_c40190 eab6653ed941344dc3173eb39d9c79b2 151 Gene3D G3DSA:3.10.180.10 9 145 8.8E-29 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c40190 eab6653ed941344dc3173eb39d9c79b2 151 SUPERFAMILY SSF54593 1 137 3.87E-26 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c14790 81fb1c7bf1c8a62d2d582c416b5f8f3a 84 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 16 56 8.0E-9 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MIM_c14790 81fb1c7bf1c8a62d2d582c416b5f8f3a 84 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 16 69 4.4E-22 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MIM_c14790 81fb1c7bf1c8a62d2d582c416b5f8f3a 84 Gene3D G3DSA:1.10.287.1040 10 83 4.3E-25 T 12-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 MIM_c14790 81fb1c7bf1c8a62d2d582c416b5f8f3a 84 SUPERFAMILY SSF116842 15 72 3.92E-19 T 12-10-2018 MIM_c14790 81fb1c7bf1c8a62d2d582c416b5f8f3a 84 Pfam PF02609 Exonuclease VII small subunit 16 66 5.8E-21 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MIM_c14790 81fb1c7bf1c8a62d2d582c416b5f8f3a 84 PIRSF PIRSF006488 3 84 2.0E-22 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MIM_c14790 81fb1c7bf1c8a62d2d582c416b5f8f3a 84 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 15 75 14.494 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MIM_c38930 2c0798bdc13eabeb18974e1e1b2873ab 129 Pfam PF01196 Ribosomal protein L17 20 116 1.6E-35 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c38930 2c0798bdc13eabeb18974e1e1b2873ab 129 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 117 1.4E-47 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c38930 2c0798bdc13eabeb18974e1e1b2873ab 129 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 27.221 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c38930 2c0798bdc13eabeb18974e1e1b2873ab 129 Gene3D G3DSA:3.90.1030.10 1 116 3.5E-48 T 12-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c38930 2c0798bdc13eabeb18974e1e1b2873ab 129 SUPERFAMILY SSF64263 1 119 1.15E-50 T 12-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c38930 2c0798bdc13eabeb18974e1e1b2873ab 129 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c27780 53924bb7df17584c7ba9eb80e077a898 398 PRINTS PR00477 Phosphoglycerate kinase family signature 192 211 1.8E-82 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c27780 53924bb7df17584c7ba9eb80e077a898 398 PRINTS PR00477 Phosphoglycerate kinase family signature 110 125 1.8E-82 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c27780 53924bb7df17584c7ba9eb80e077a898 398 PRINTS PR00477 Phosphoglycerate kinase family signature 314 339 1.8E-82 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c27780 53924bb7df17584c7ba9eb80e077a898 398 PRINTS PR00477 Phosphoglycerate kinase family signature 37 59 1.8E-82 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c27780 53924bb7df17584c7ba9eb80e077a898 398 PRINTS PR00477 Phosphoglycerate kinase family signature 347 358 1.8E-82 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c27780 53924bb7df17584c7ba9eb80e077a898 398 PRINTS PR00477 Phosphoglycerate kinase family signature 138 160 1.8E-82 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c27780 53924bb7df17584c7ba9eb80e077a898 398 PRINTS PR00477 Phosphoglycerate kinase family signature 169 191 1.8E-82 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c27780 53924bb7df17584c7ba9eb80e077a898 398 PRINTS PR00477 Phosphoglycerate kinase family signature 15 31 1.8E-82 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c27780 53924bb7df17584c7ba9eb80e077a898 398 PRINTS PR00477 Phosphoglycerate kinase family signature 370 387 1.8E-82 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c27780 53924bb7df17584c7ba9eb80e077a898 398 SUPERFAMILY SSF53748 13 394 8.72E-142 T 12-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c27780 53924bb7df17584c7ba9eb80e077a898 398 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 6 394 39.49 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c27780 53924bb7df17584c7ba9eb80e077a898 398 Pfam PF00162 Phosphoglycerate kinase 15 384 3.4E-141 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c27780 53924bb7df17584c7ba9eb80e077a898 398 Gene3D G3DSA:3.40.50.1260 171 384 3.5E-148 T 12-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c27780 53924bb7df17584c7ba9eb80e077a898 398 Gene3D G3DSA:3.40.50.1260 15 392 3.5E-148 T 12-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c27780 53924bb7df17584c7ba9eb80e077a898 398 PIRSF PIRSF000724 1 398 1.2E-138 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c27780 53924bb7df17584c7ba9eb80e077a898 398 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 20 30 - T 12-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MIM_c13550 7b3b6c9658606cee097179ce93c991b9 190 Pfam PF07879 PHB/PHA accumulation regulator DNA-binding domain 12 71 1.4E-29 T 12-10-2018 IPR012909 PHA accumulation regulator DNA-binding, N-terminal MIM_c13550 7b3b6c9658606cee097179ce93c991b9 190 Pfam PF05233 PHB accumulation regulatory domain 76 114 1.5E-19 T 12-10-2018 IPR007897 PHB accumulation regulatory MIM_c13550 7b3b6c9658606cee097179ce93c991b9 190 Pfam PF05233 PHB accumulation regulatory domain 126 165 4.6E-14 T 12-10-2018 IPR007897 PHB accumulation regulatory MIM_c13550 7b3b6c9658606cee097179ce93c991b9 190 TIGRFAM TIGR01848 PHA_reg_PhaR: polyhydroxyalkanoate synthesis repressor PhaR 12 117 1.2E-43 T 12-10-2018 IPR010134 Polyhydroxyalkanoate synthesis repressor PhaR GO:0006355 MIM_c01930 4dbf05062b2525928831fac95db9b6c8 334 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 35 318 4.7E-112 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 MIM_c01930 4dbf05062b2525928831fac95db9b6c8 334 PIRSF PIRSF006470 1 334 1.7E-133 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 MIM_c01930 4dbf05062b2525928831fac95db9b6c8 334 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 35 289 6.1E-88 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 MIM_c01930 4dbf05062b2525928831fac95db9b6c8 334 Gene3D G3DSA:3.40.190.170 30 332 9.3E-102 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily MIM_c01930 4dbf05062b2525928831fac95db9b6c8 334 SUPERFAMILY SSF53850 39 268 1.33E-5 T 12-10-2018 MIM_c10420 397401bdf6a5fdbf52b09efaf15c7f88 93 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 1 93 22.373 T 12-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 MIM_c10420 397401bdf6a5fdbf52b09efaf15c7f88 93 SUPERFAMILY SSF55248 1 93 6.15E-34 T 12-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 MIM_c10420 397401bdf6a5fdbf52b09efaf15c7f88 93 Gene3D G3DSA:3.30.1360.20 2 93 9.5E-36 T 12-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 MIM_c10420 397401bdf6a5fdbf52b09efaf15c7f88 93 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 3 92 8.6E-32 T 12-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 MIM_c37140 2f40fd9e7a5aa4f0a7bedbf310826989 286 SUPERFAMILY SSF52467 8 275 4.63E-62 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MIM_c37140 2f40fd9e7a5aa4f0a7bedbf310826989 286 Gene3D G3DSA:3.40.50.1220 20 269 1.4E-39 T 12-10-2018 MIM_c37140 2f40fd9e7a5aa4f0a7bedbf310826989 286 Gene3D G3DSA:3.30.1600.10 37 192 1.4E-39 T 12-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily MIM_c37140 2f40fd9e7a5aa4f0a7bedbf310826989 286 Pfam PF02146 Sir2 family 28 191 5.3E-20 T 12-10-2018 IPR003000 Sirtuin family GO:0070403 MIM_c07730 2e5747f99fd347a530e3f253657cc013 142 SUPERFAMILY SSF51306 22 139 8.89E-32 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily MIM_c07730 2e5747f99fd347a530e3f253657cc013 142 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 65 76 2.4E-8 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MIM_c07730 2e5747f99fd347a530e3f253657cc013 142 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 93 105 2.4E-8 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MIM_c07730 2e5747f99fd347a530e3f253657cc013 142 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 54 64 2.4E-8 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MIM_c07730 2e5747f99fd347a530e3f253657cc013 142 Gene3D G3DSA:2.10.109.10 27 141 5.9E-41 T 12-10-2018 MIM_c07730 2e5747f99fd347a530e3f253657cc013 142 Pfam PF00717 Peptidase S24-like 58 120 1.1E-13 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MIM_c25490 4152f4d0441ac89089da73cd1b4acb57 325 Gene3D G3DSA:3.40.190.150 28 314 2.9E-104 T 12-10-2018 MIM_c25490 4152f4d0441ac89089da73cd1b4acb57 325 SUPERFAMILY SSF53850 108 286 5.85E-14 T 12-10-2018 MIM_c25490 4152f4d0441ac89089da73cd1b4acb57 325 Gene3D G3DSA:3.40.190.10 126 249 2.9E-104 T 12-10-2018 MIM_c25490 4152f4d0441ac89089da73cd1b4acb57 325 PIRSF PIRSF017082 2 323 1.9E-70 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c25490 4152f4d0441ac89089da73cd1b4acb57 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 320 4.2E-80 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c08520 70c92f2af3f7465284b80f450cff3bb8 413 SUPERFAMILY SSF89796 6 400 6.8E-105 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c08520 70c92f2af3f7465284b80f450cff3bb8 413 Pfam PF02515 CoA-transferase family III 11 378 2.3E-93 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 MIM_c08520 70c92f2af3f7465284b80f450cff3bb8 413 Gene3D G3DSA:3.40.50.10540 10 394 6.0E-100 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c08520 70c92f2af3f7465284b80f450cff3bb8 413 Gene3D G3DSA:3.30.1540.10 236 329 6.0E-100 T 12-10-2018 MIM_c23550 b122b6e1ff0755a9ffad3258e1417a06 605 Pfam PF16188 C-terminal region of peptidase_M24 546 605 9.0E-22 T 12-10-2018 IPR032416 Peptidase M24, C-terminal domain MIM_c23550 b122b6e1ff0755a9ffad3258e1417a06 605 Pfam PF01321 Creatinase/Prolidase N-terminal domain 17 143 1.6E-18 T 12-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 MIM_c23550 b122b6e1ff0755a9ffad3258e1417a06 605 Gene3D G3DSA:3.90.230.10 313 605 4.6E-93 T 12-10-2018 MIM_c23550 b122b6e1ff0755a9ffad3258e1417a06 605 Pfam PF00557 Metallopeptidase family M24 319 533 3.0E-39 T 12-10-2018 IPR000994 Peptidase M24 MIM_c23550 b122b6e1ff0755a9ffad3258e1417a06 605 SUPERFAMILY SSF55920 313 571 1.1E-52 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like MIM_c23550 b122b6e1ff0755a9ffad3258e1417a06 605 Gene3D G3DSA:3.40.350.10 10 158 3.6E-45 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MIM_c23550 b122b6e1ff0755a9ffad3258e1417a06 605 Gene3D G3DSA:3.40.350.10 159 312 2.9E-32 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MIM_c23550 b122b6e1ff0755a9ffad3258e1417a06 605 SUPERFAMILY SSF53092 10 143 5.76E-13 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MIM_c23550 b122b6e1ff0755a9ffad3258e1417a06 605 Pfam PF16189 Creatinase/Prolidase N-terminal domain 160 316 4.0E-39 T 12-10-2018 MIM_c00090 ff26eab942ae8706105f0f7ff3e82734 707 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 614 686 6.2E-10 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c00090 ff26eab942ae8706105f0f7ff3e82734 707 Gene3D G3DSA:2.140.10.10 23 599 2.5E-223 T 12-10-2018 MIM_c00090 ff26eab942ae8706105f0f7ff3e82734 707 SUPERFAMILY SSF50998 44 570 8.5E-160 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MIM_c00090 ff26eab942ae8706105f0f7ff3e82734 707 SMART SM00564 145 176 2.9E-6 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c00090 ff26eab942ae8706105f0f7ff3e82734 707 SMART SM00564 504 535 3.0E-5 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c00090 ff26eab942ae8706105f0f7ff3e82734 707 SMART SM00564 191 228 15.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c00090 ff26eab942ae8706105f0f7ff3e82734 707 SMART SM00564 92 124 6.2E-8 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c00090 ff26eab942ae8706105f0f7ff3e82734 707 SMART SM00564 294 321 93.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c00090 ff26eab942ae8706105f0f7ff3e82734 707 Pfam PF13360 PQQ-like domain 471 550 5.9E-10 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat MIM_c00090 ff26eab942ae8706105f0f7ff3e82734 707 Pfam PF13360 PQQ-like domain 107 231 8.4E-15 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat MIM_c00090 ff26eab942ae8706105f0f7ff3e82734 707 TIGRFAM TIGR03075 PQQ_enz_alc_DH: PQQ-dependent dehydrogenase, methanol/ethanol family 31 563 9.4E-192 T 12-10-2018 IPR017512 PQQ-dependent dehydrogenase, methanol/ethanol family GO:0005509|GO:0016020|GO:0016614|GO:0055114 MIM_c00090 ff26eab942ae8706105f0f7ff3e82734 707 SUPERFAMILY SSF46626 605 689 8.24E-17 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c00090 ff26eab942ae8706105f0f7ff3e82734 707 Gene3D G3DSA:1.10.760.10 601 696 3.2E-18 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c19770 29d963b260c70a9a069729971086ba15 440 Pfam PF01546 Peptidase family M20/M25/M40 119 418 1.1E-19 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 MIM_c19770 29d963b260c70a9a069729971086ba15 440 Pfam PF07687 Peptidase dimerisation domain 222 317 8.4E-14 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain MIM_c19770 29d963b260c70a9a069729971086ba15 440 SUPERFAMILY SSF53187 57 426 7.43E-44 T 12-10-2018 MIM_c19770 29d963b260c70a9a069729971086ba15 440 Gene3D G3DSA:3.40.630.10 69 406 3.2E-56 T 12-10-2018 MIM_c19770 29d963b260c70a9a069729971086ba15 440 SUPERFAMILY SSF55031 222 326 4.34E-14 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain MIM_c19770 29d963b260c70a9a069729971086ba15 440 Gene3D G3DSA:3.30.70.360 221 342 3.2E-56 T 12-10-2018 MIM_c22360 23614186be9727b9c88fbbef86f36090 505 SMART SM00858 11 78 1.4E-9 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 MIM_c22360 23614186be9727b9c88fbbef86f36090 505 Pfam PF08666 SAF domain 11 76 1.4E-9 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 MIM_c22360 23614186be9727b9c88fbbef86f36090 505 Gene3D G3DSA:3.90.1210.30 3 79 3.5E-21 T 12-10-2018 MIM_c22360 23614186be9727b9c88fbbef86f36090 505 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 103 503 5.2E-160 T 12-10-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 MIM_c38280 72d7eb6714795dc5af5e2db659656465 326 Gene3D G3DSA:3.40.190.10 128 251 1.6E-109 T 12-10-2018 MIM_c38280 72d7eb6714795dc5af5e2db659656465 326 Gene3D G3DSA:3.40.190.150 31 316 1.6E-109 T 12-10-2018 MIM_c38280 72d7eb6714795dc5af5e2db659656465 326 PIRSF PIRSF017082 2 325 3.5E-82 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c38280 72d7eb6714795dc5af5e2db659656465 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 323 9.1E-89 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c38280 72d7eb6714795dc5af5e2db659656465 326 SUPERFAMILY SSF53850 118 288 5.55E-14 T 12-10-2018 MIM_c23370 59e745a21e0567d867fa3ee1f8a00431 214 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 2 213 3.6E-88 T 12-10-2018 IPR005955 Glutathione S-transferases, class Zeta GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-204174|Reactome: R-HSA-71182 MIM_c23370 59e745a21e0567d867fa3ee1f8a00431 214 Pfam PF14497 Glutathione S-transferase, C-terminal domain 126 191 4.3E-5 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal MIM_c23370 59e745a21e0567d867fa3ee1f8a00431 214 SUPERFAMILY SSF47616 82 212 6.96E-32 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MIM_c23370 59e745a21e0567d867fa3ee1f8a00431 214 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 80 1.9E-13 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MIM_c23370 59e745a21e0567d867fa3ee1f8a00431 214 SUPERFAMILY SSF52833 1 106 1.12E-20 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c23370 59e745a21e0567d867fa3ee1f8a00431 214 Gene3D G3DSA:3.40.30.10 3 81 5.6E-23 T 12-10-2018 MIM_c23370 59e745a21e0567d867fa3ee1f8a00431 214 Gene3D G3DSA:1.20.1050.10 85 214 8.9E-54 T 12-10-2018 MIM_c18850 24a7f80b17b5a01926d634e3cf677fc7 776 Gene3D G3DSA:3.10.20.30 437 512 6.2E-30 T 12-10-2018 IPR012675 Beta-grasp domain superfamily MIM_c18850 24a7f80b17b5a01926d634e3cf677fc7 776 SMART SM00954 291 401 1.2E-60 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 MIM_c18850 24a7f80b17b5a01926d634e3cf677fc7 776 Gene3D G3DSA:1.10.3210.10 55 246 1.4E-77 T 12-10-2018 MIM_c18850 24a7f80b17b5a01926d634e3cf677fc7 776 Gene3D G3DSA:3.30.70.260 690 771 2.8E-11 T 12-10-2018 MIM_c18850 24a7f80b17b5a01926d634e3cf677fc7 776 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 82 764 3.2E-228 T 12-10-2018 IPR004811 RelA/SpoT family GO:0015969 MIM_c18850 24a7f80b17b5a01926d634e3cf677fc7 776 Pfam PF13291 ACT domain 691 765 8.6E-16 T 12-10-2018 IPR002912 ACT domain MIM_c18850 24a7f80b17b5a01926d634e3cf677fc7 776 SUPERFAMILY SSF81271 431 504 1.94E-21 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MIM_c18850 24a7f80b17b5a01926d634e3cf677fc7 776 SUPERFAMILY SSF109604 60 244 5.18E-71 T 12-10-2018 MIM_c18850 24a7f80b17b5a01926d634e3cf677fc7 776 Gene3D G3DSA:3.30.460.10 249 381 7.8E-46 T 12-10-2018 MIM_c18850 24a7f80b17b5a01926d634e3cf677fc7 776 SUPERFAMILY SSF55021 690 765 2.46E-6 T 12-10-2018 MIM_c18850 24a7f80b17b5a01926d634e3cf677fc7 776 Pfam PF02824 TGS domain 444 503 7.7E-22 T 12-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 MIM_c18850 24a7f80b17b5a01926d634e3cf677fc7 776 SMART SM00471 97 209 4.1E-10 T 12-10-2018 IPR003607 HD/PDEase domain MIM_c18850 24a7f80b17b5a01926d634e3cf677fc7 776 Pfam PF13328 HD domain 82 231 2.3E-48 T 12-10-2018 IPR003607 HD/PDEase domain MIM_c18850 24a7f80b17b5a01926d634e3cf677fc7 776 Pfam PF04607 Region found in RelA / SpoT proteins 291 400 8.2E-34 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 MIM_c18850 24a7f80b17b5a01926d634e3cf677fc7 776 SUPERFAMILY SSF81301 237 448 3.92E-59 T 12-10-2018 MIM_c28160 f476bcb58bb76b9040e21e9cab843428 225 Pfam PF09223 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment 46 225 1.0E-80 T 12-10-2018 IPR015304 ZinT domain GO:0008270 MIM_c28160 f476bcb58bb76b9040e21e9cab843428 225 Gene3D G3DSA:2.40.128.20 41 225 8.5E-78 T 12-10-2018 IPR012674 Calycin MIM_c28160 f476bcb58bb76b9040e21e9cab843428 225 SUPERFAMILY SSF50814 43 225 1.08E-74 T 12-10-2018 IPR012674 Calycin MIM_c15240 0554bd8db91d2d4b78594d82c27d37ab 319 SUPERFAMILY SSF53756 7 318 8.63E-45 T 12-10-2018 MIM_c15240 0554bd8db91d2d4b78594d82c27d37ab 319 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 84 298 7.1E-39 T 12-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 MIM_c15240 0554bd8db91d2d4b78594d82c27d37ab 319 Gene3D G3DSA:3.40.50.2000 6 143 1.4E-13 T 12-10-2018 MIM_c15240 0554bd8db91d2d4b78594d82c27d37ab 319 Gene3D G3DSA:3.40.50.2000 166 316 2.2E-23 T 12-10-2018 MIM_c21780 6ba7a05b4372fe6180dae19596f4ee0b 385 PIRSF PIRSF000138 1 385 9.7E-125 T 12-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 MIM_c21780 6ba7a05b4372fe6180dae19596f4ee0b 385 Gene3D G3DSA:3.20.20.70 5 384 2.6E-130 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c21780 6ba7a05b4372fe6180dae19596f4ee0b 385 SUPERFAMILY SSF51395 7 379 3.11E-102 T 12-10-2018 MIM_c21780 6ba7a05b4372fe6180dae19596f4ee0b 385 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 277 283 - T 12-10-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Reactome: R-HSA-9033241 MIM_c21780 6ba7a05b4372fe6180dae19596f4ee0b 385 Pfam PF01070 FMN-dependent dehydrogenase 17 380 2.5E-131 T 12-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 MIM_c06640 1eab6fbe3014aeabc05d5bd3addeb580 389 Pfam PF01734 Patatin-like phospholipase 12 225 5.4E-21 T 12-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 MIM_c06640 1eab6fbe3014aeabc05d5bd3addeb580 389 Gene3D G3DSA:3.40.1090.10 3 104 6.3E-16 T 12-10-2018 MIM_c06640 1eab6fbe3014aeabc05d5bd3addeb580 389 Gene3D G3DSA:3.40.1090.10 131 290 2.4E-18 T 12-10-2018 MIM_c06640 1eab6fbe3014aeabc05d5bd3addeb580 389 Pfam PF12536 Patatin phospholipase 262 368 3.7E-35 T 12-10-2018 IPR021095 Protein of unknown function DUF3734 MIM_c06640 1eab6fbe3014aeabc05d5bd3addeb580 389 SUPERFAMILY SSF52151 9 356 3.4E-50 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase MIM_c36480 faf53d051590a55e6b2b71cde85f7f67 438 Pfam PF05977 Transmembrane secretion effector 9 401 5.5E-56 T 12-10-2018 IPR010290 Transmembrane secretion effector MIM_c36480 faf53d051590a55e6b2b71cde85f7f67 438 Gene3D G3DSA:1.20.1250.20 15 400 4.8E-45 T 12-10-2018 MIM_c36480 faf53d051590a55e6b2b71cde85f7f67 438 SUPERFAMILY SSF103473 16 403 2.22E-50 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c19360 f71bb8f3fadbb48446f408a94e983082 186 TIGRFAM TIGR00496 frr: ribosome recycling factor 12 186 5.3E-69 T 12-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 MIM_c19360 f71bb8f3fadbb48446f408a94e983082 186 Pfam PF01765 Ribosome recycling factor 21 184 2.6E-62 T 12-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 MIM_c19360 f71bb8f3fadbb48446f408a94e983082 186 Gene3D G3DSA:1.10.132.20 13 183 2.5E-65 T 12-10-2018 MIM_c19360 f71bb8f3fadbb48446f408a94e983082 186 Hamap MF_00040 Ribosome-recycling factor [frr]. 4 186 26.862 T 12-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 MIM_c19360 f71bb8f3fadbb48446f408a94e983082 186 Gene3D G3DSA:3.30.1360.40 32 106 2.5E-65 T 12-10-2018 MIM_c19360 f71bb8f3fadbb48446f408a94e983082 186 SUPERFAMILY SSF55194 5 185 2.35E-69 T 12-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 MIM_c13600 db76de823f0ea9fb36b07047112a7fd2 365 Gene3D G3DSA:3.30.1300.30 263 365 4.4E-20 T 12-10-2018 MIM_c13600 db76de823f0ea9fb36b07047112a7fd2 365 Pfam PF05658 Head domain of trimeric autotransporter adhesin 44 68 3.1E-7 T 12-10-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 MIM_c13600 db76de823f0ea9fb36b07047112a7fd2 365 SUPERFAMILY SSF54523 271 365 9.57E-19 T 12-10-2018 MIM_c13600 db76de823f0ea9fb36b07047112a7fd2 365 Gene3D G3DSA:2.150.10.10 24 135 2.0E-16 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MIM_c13600 db76de823f0ea9fb36b07047112a7fd2 365 Pfam PF03895 YadA-like membrane anchor domain 309 365 1.2E-8 T 12-10-2018 IPR005594 YadA-like, C-terminal MIM_c13600 db76de823f0ea9fb36b07047112a7fd2 365 SUPERFAMILY SSF101967 34 127 1.02E-11 T 12-10-2018 MIM_c35410 44736b9fe5a50f82e2569c39c696af18 313 Gene3D G3DSA:3.40.50.720 104 299 2.0E-109 T 12-10-2018 MIM_c35410 44736b9fe5a50f82e2569c39c696af18 313 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 283 2.4E-49 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MIM_c35410 44736b9fe5a50f82e2569c39c696af18 313 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 19 312 2.7E-18 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 MIM_c35410 44736b9fe5a50f82e2569c39c696af18 313 Gene3D G3DSA:3.40.50.720 3 305 2.0E-109 T 12-10-2018 MIM_c35410 44736b9fe5a50f82e2569c39c696af18 313 SUPERFAMILY SSF52283 20 126 2.98E-23 T 12-10-2018 MIM_c35410 44736b9fe5a50f82e2569c39c696af18 313 SUPERFAMILY SSF51735 102 284 2.15E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c00940 2cf244d9b60381b38c04674c41dc139d 231 Pfam PF00043 Glutathione S-transferase, C-terminal domain 137 220 3.3E-9 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal MIM_c00940 2cf244d9b60381b38c04674c41dc139d 231 Gene3D G3DSA:3.40.30.10 6 228 1.3E-105 T 12-10-2018 MIM_c00940 2cf244d9b60381b38c04674c41dc139d 231 Pfam PF02798 Glutathione S-transferase, N-terminal domain 19 96 6.2E-13 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MIM_c00940 2cf244d9b60381b38c04674c41dc139d 231 SUPERFAMILY SSF47616 100 223 7.8E-31 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MIM_c00940 2cf244d9b60381b38c04674c41dc139d 231 SUPERFAMILY SSF52833 9 100 6.28E-22 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c00940 2cf244d9b60381b38c04674c41dc139d 231 Gene3D G3DSA:1.20.1050.10 104 219 1.3E-105 T 12-10-2018 MIM_c18710 2121a42e25a06396c1153ab276eac948 110 SUPERFAMILY SSF51182 22 89 1.46E-11 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c18710 2121a42e25a06396c1153ab276eac948 110 Gene3D G3DSA:2.60.120.10 6 109 1.5E-6 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c39020 1cd090c0f57d91bf17ef66cabc1be1c5 173 SUPERFAMILY SSF54211 86 166 1.69E-24 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MIM_c39020 1cd090c0f57d91bf17ef66cabc1be1c5 173 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 17 170 1.1E-63 T 12-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 MIM_c39020 1cd090c0f57d91bf17ef66cabc1be1c5 173 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 170 34.095 T 12-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 MIM_c39020 1cd090c0f57d91bf17ef66cabc1be1c5 173 ProSitePatterns PS00585 Ribosomal protein S5 signature. 35 67 - T 12-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site MIM_c39020 1cd090c0f57d91bf17ef66cabc1be1c5 173 Gene3D G3DSA:3.30.230.10 81 173 3.8E-35 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MIM_c39020 1cd090c0f57d91bf17ef66cabc1be1c5 173 Pfam PF00333 Ribosomal protein S5, N-terminal domain 18 81 7.5E-25 T 12-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 MIM_c39020 1cd090c0f57d91bf17ef66cabc1be1c5 173 Gene3D G3DSA:3.30.160.20 9 79 1.8E-27 T 12-10-2018 MIM_c39020 1cd090c0f57d91bf17ef66cabc1be1c5 173 SUPERFAMILY SSF54768 15 82 3.03E-21 T 12-10-2018 MIM_c39020 1cd090c0f57d91bf17ef66cabc1be1c5 173 Pfam PF03719 Ribosomal protein S5, C-terminal domain 94 164 1.5E-27 T 12-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 MIM_c29530 110db5d74f9d9d76dd482f8d9a57a97f 249 Pfam PF01553 Acyltransferase 65 177 3.0E-21 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MIM_c29530 110db5d74f9d9d76dd482f8d9a57a97f 249 SUPERFAMILY SSF69593 11 242 2.09E-23 T 12-10-2018 MIM_c29530 110db5d74f9d9d76dd482f8d9a57a97f 249 SMART SM00563 68 180 6.6E-28 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MIM_c34100 3c6ff7d7815c3efa863a66e6adc3ac11 379 Gene3D G3DSA:1.20.140.10 237 369 3.3E-5 T 12-10-2018 MIM_c34100 3c6ff7d7815c3efa863a66e6adc3ac11 379 Gene3D G3DSA:2.40.110.10 134 228 4.1E-10 T 12-10-2018 MIM_c34100 3c6ff7d7815c3efa863a66e6adc3ac11 379 SUPERFAMILY SSF56645 20 228 1.11E-24 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c34100 3c6ff7d7815c3efa863a66e6adc3ac11 379 SUPERFAMILY SSF47203 281 373 1.29E-5 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c34100 3c6ff7d7815c3efa863a66e6adc3ac11 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 20 98 5.8E-6 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c34100 3c6ff7d7815c3efa863a66e6adc3ac11 379 Gene3D G3DSA:1.10.540.10 18 123 6.6E-8 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c33310 2def0708cbd1800d3116413127010297 319 Gene3D G3DSA:3.40.50.300 42 318 2.0E-19 T 12-10-2018 MIM_c33310 2def0708cbd1800d3116413127010297 319 SUPERFAMILY SSF52540 134 308 1.14E-13 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c33310 2def0708cbd1800d3116413127010297 319 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 129 308 1.5E-17 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MIM_c35330 3d6b886a1a8a35f7afc14dce780b2686 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 255 3.4E-54 T 12-10-2018 MIM_c35330 3d6b886a1a8a35f7afc14dce780b2686 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 8.1E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c35330 3d6b886a1a8a35f7afc14dce780b2686 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 8.1E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c35330 3d6b886a1a8a35f7afc14dce780b2686 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 93 104 8.1E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c35330 3d6b886a1a8a35f7afc14dce780b2686 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 8.9E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c35330 3d6b886a1a8a35f7afc14dce780b2686 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 8.9E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c35330 3d6b886a1a8a35f7afc14dce780b2686 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 8.9E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c35330 3d6b886a1a8a35f7afc14dce780b2686 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 8.9E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c35330 3d6b886a1a8a35f7afc14dce780b2686 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 8.9E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c35330 3d6b886a1a8a35f7afc14dce780b2686 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 8.9E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c35330 3d6b886a1a8a35f7afc14dce780b2686 256 SUPERFAMILY SSF51735 6 255 6.55E-74 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c35330 3d6b886a1a8a35f7afc14dce780b2686 256 Gene3D G3DSA:3.40.50.720 3 256 6.4E-75 T 12-10-2018 MIM_c35330 3d6b886a1a8a35f7afc14dce780b2686 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 221 0.0027 T 12-10-2018 MIM_c35330 3d6b886a1a8a35f7afc14dce780b2686 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c32170 1fed3e5cd72df6b7f2f1f04af23f1e7c 285 Gene3D G3DSA:1.10.12.10 227 285 2.2E-16 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MIM_c32170 1fed3e5cd72df6b7f2f1f04af23f1e7c 285 SUPERFAMILY SSF52096 28 284 1.53E-72 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c32170 1fed3e5cd72df6b7f2f1f04af23f1e7c 285 Gene3D G3DSA:3.90.226.10 10 226 8.4E-63 T 12-10-2018 MIM_c32170 1fed3e5cd72df6b7f2f1f04af23f1e7c 285 Pfam PF00378 Enoyl-CoA hydratase/isomerase 33 284 1.0E-42 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c32170 1fed3e5cd72df6b7f2f1f04af23f1e7c 285 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 125 145 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 MIM_c19130 7cbcec20bf74d741c5fc4c9de80462ef 233 SUPERFAMILY SSF52540 2 230 5.11E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c19130 7cbcec20bf74d741c5fc4c9de80462ef 233 PIRSF PIRSF039137 1 233 8.7E-104 T 12-10-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 MIM_c19130 7cbcec20bf74d741c5fc4c9de80462ef 233 Pfam PF00005 ABC transporter 17 161 2.2E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c19130 7cbcec20bf74d741c5fc4c9de80462ef 233 Gene3D G3DSA:3.40.50.300 1 233 1.0E-60 T 12-10-2018 MIM_c19130 7cbcec20bf74d741c5fc4c9de80462ef 233 SMART SM00382 26 212 4.1E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c19130 7cbcec20bf74d741c5fc4c9de80462ef 233 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c33160 3e3fb9e2a35244abc1a57dbdd6d42d69 474 SUPERFAMILY SSF52540 42 371 4.25E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c33160 3e3fb9e2a35244abc1a57dbdd6d42d69 474 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 2.4E-18 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MIM_c33160 3e3fb9e2a35244abc1a57dbdd6d42d69 474 SMART SM00963 1 86 1.5E-32 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MIM_c33160 3e3fb9e2a35244abc1a57dbdd6d42d69 474 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 282 295 - T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MIM_c33160 3e3fb9e2a35244abc1a57dbdd6d42d69 474 SMART SM00382 103 314 1.8E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c33160 3e3fb9e2a35244abc1a57dbdd6d42d69 474 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 453 32.736 T 12-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 MIM_c33160 3e3fb9e2a35244abc1a57dbdd6d42d69 474 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 443 5.7E-166 T 12-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 MIM_c33160 3e3fb9e2a35244abc1a57dbdd6d42d69 474 Gene3D G3DSA:1.10.260.30 341 467 5.3E-42 T 12-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 MIM_c33160 3e3fb9e2a35244abc1a57dbdd6d42d69 474 SMART SM00962 104 309 2.8E-103 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MIM_c33160 3e3fb9e2a35244abc1a57dbdd6d42d69 474 Gene3D G3DSA:3.40.50.300 95 298 1.4E-114 T 12-10-2018 MIM_c33160 3e3fb9e2a35244abc1a57dbdd6d42d69 474 Pfam PF00448 SRP54-type protein, GTPase domain 105 308 1.5E-65 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MIM_c33160 3e3fb9e2a35244abc1a57dbdd6d42d69 474 Pfam PF02978 Signal peptide binding domain 342 441 7.9E-32 T 12-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 MIM_c33160 3e3fb9e2a35244abc1a57dbdd6d42d69 474 Gene3D G3DSA:1.20.120.140 4 319 1.4E-114 T 12-10-2018 MIM_c33160 3e3fb9e2a35244abc1a57dbdd6d42d69 474 SUPERFAMILY SSF47446 341 444 1.64E-34 T 12-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 MIM_c14160 a6f32ba0c8765caca419aca4ac58f44f 299 TIGRFAM TIGR03709 PPK2_rel_1: polyphosphate:nucleotide phosphotransferase, PPK2 family 11 282 1.5E-112 T 12-10-2018 IPR022300 Polyphosphate:nucleotide phosphotransferase, PPK2 GO:0006797|GO:0016776 KEGG: 00190+2.7.4.1 MIM_c14160 a6f32ba0c8765caca419aca4ac58f44f 299 SUPERFAMILY SSF52540 68 267 3.06E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c14160 a6f32ba0c8765caca419aca4ac58f44f 299 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 35 267 5.3E-65 T 12-10-2018 IPR022488 Polyphosphate kinase-2-related MIM_c14160 a6f32ba0c8765caca419aca4ac58f44f 299 PIRSF PIRSF028756 9 299 3.9E-83 T 12-10-2018 IPR016898 Polyphosphate kinase 2 KEGG: 00190+2.7.4.1 MIM_c14160 a6f32ba0c8765caca419aca4ac58f44f 299 Gene3D G3DSA:3.40.50.300 4 287 2.0E-105 T 12-10-2018 MIM_c15180 0567710e1f216d792d08bb301539c42b 1174 Pfam PF14579 Helix-hairpin-helix motif 808 906 4.4E-28 T 12-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MIM_c15180 0567710e1f216d792d08bb301539c42b 1174 SMART SM00481 11 78 1.5E-22 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal MIM_c15180 0567710e1f216d792d08bb301539c42b 1174 SUPERFAMILY SSF89550 10 266 1.12E-10 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MIM_c15180 0567710e1f216d792d08bb301539c42b 1174 Gene3D G3DSA:1.10.10.1600 437 516 7.1E-27 T 12-10-2018 MIM_c15180 0567710e1f216d792d08bb301539c42b 1174 Gene3D G3DSA:3.20.20.140 2 273 1.3E-85 T 12-10-2018 MIM_c15180 0567710e1f216d792d08bb301539c42b 1174 Pfam PF02811 PHP domain 12 175 6.9E-43 T 12-10-2018 IPR004013 PHP domain GO:0003824 MIM_c15180 0567710e1f216d792d08bb301539c42b 1174 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 10 1039 0.0 T 12-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MIM_c15180 0567710e1f216d792d08bb301539c42b 1174 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 295 735 1.2E-172 T 12-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MIM_c36000 d7c3eb27b49672e77d58446903ebe7b6 109 SUPERFAMILY SSF143100 5 72 1.1E-6 T 12-10-2018 IPR035069 TTHA1013/TTHA0281-like MIM_c36000 d7c3eb27b49672e77d58446903ebe7b6 109 SUPERFAMILY SSF47598 72 107 1.65E-6 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 MIM_c36000 d7c3eb27b49672e77d58446903ebe7b6 109 Pfam PF05534 HicB family 61 107 2.9E-15 T 12-10-2018 IPR008651 Uncharacterised protein family HicB MIM_c09260 339f7996a1d87670657d2b75b5f98892 478 Pfam PF02321 Outer membrane efflux protein 284 464 4.5E-27 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MIM_c09260 339f7996a1d87670657d2b75b5f98892 478 Pfam PF02321 Outer membrane efflux protein 76 257 4.6E-24 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MIM_c09260 339f7996a1d87670657d2b75b5f98892 478 SUPERFAMILY SSF56954 10 468 2.09E-104 T 12-10-2018 MIM_c09260 339f7996a1d87670657d2b75b5f98892 478 Gene3D G3DSA:1.20.1600.10 66 467 7.8E-127 T 12-10-2018 MIM_c09260 339f7996a1d87670657d2b75b5f98892 478 Gene3D G3DSA:2.20.200.10 113 355 7.8E-127 T 12-10-2018 MIM_c09260 339f7996a1d87670657d2b75b5f98892 478 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 22 466 8.9E-120 T 12-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 MIM_c19800 dc5af963aede62af9e4cbf2267be2041 278 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 45 266 7.4E-36 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c19800 dc5af963aede62af9e4cbf2267be2041 278 SUPERFAMILY SSF53850 34 269 4.48E-44 T 12-10-2018 MIM_c19800 dc5af963aede62af9e4cbf2267be2041 278 Gene3D G3DSA:3.40.190.10 123 228 4.0E-37 T 12-10-2018 MIM_c19800 dc5af963aede62af9e4cbf2267be2041 278 SMART SM00062 38 269 7.5E-20 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c19800 dc5af963aede62af9e4cbf2267be2041 278 Gene3D G3DSA:3.40.190.10 46 265 4.0E-37 T 12-10-2018 MIM_c11910 912d54f74167e72f42d8c3526d534766 380 SUPERFAMILY SSF53383 1 379 7.05E-102 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c11910 912d54f74167e72f42d8c3526d534766 380 Gene3D G3DSA:3.40.640.10 40 278 1.2E-130 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c11910 912d54f74167e72f42d8c3526d534766 380 Gene3D G3DSA:3.90.1150.10 18 377 1.2E-130 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c11910 912d54f74167e72f42d8c3526d534766 380 Pfam PF00155 Aminotransferase class I and II 27 377 1.1E-61 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MIM_c24170 f3154a293693566c3243befeb86fffd3 420 TIGRFAM TIGR01849 PHB_depoly_PhaZ: polyhydroxyalkanoate depolymerase, intracellular 2 407 4.0E-177 T 12-10-2018 IPR010915 Polyhydroxyalkanoate depolymerase MIM_c24170 f3154a293693566c3243befeb86fffd3 420 SUPERFAMILY SSF53474 93 405 1.15E-31 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c24170 f3154a293693566c3243befeb86fffd3 420 PIRSF PIRSF020818 1 420 3.4E-190 T 12-10-2018 IPR010915 Polyhydroxyalkanoate depolymerase MIM_c24170 f3154a293693566c3243befeb86fffd3 420 Pfam PF06850 PHB de-polymerase C-terminus 207 408 3.8E-90 T 12-10-2018 IPR009656 PHB de-polymerase, C-terminal MIM_c02840 3eaa124a54d4668c841748da5fdb8c13 322 Pfam PF00005 ABC transporter 24 175 8.3E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c02840 3eaa124a54d4668c841748da5fdb8c13 322 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 227 313 1.1E-22 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c02840 3eaa124a54d4668c841748da5fdb8c13 322 Gene3D G3DSA:3.40.50.300 1 321 7.4E-99 T 12-10-2018 MIM_c02840 3eaa124a54d4668c841748da5fdb8c13 322 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c02840 3eaa124a54d4668c841748da5fdb8c13 322 SMART SM00382 32 241 1.1E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c02840 3eaa124a54d4668c841748da5fdb8c13 322 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 228 294 2.2E-15 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c02840 3eaa124a54d4668c841748da5fdb8c13 322 SUPERFAMILY SSF52540 2 246 6.08E-72 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c04890 d28d748bfd8354aa3e112d63c6b08657 267 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 10 264 47.404 T 12-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 MIM_c04890 d28d748bfd8354aa3e112d63c6b08657 267 SUPERFAMILY SSF51366 11 264 1.65E-79 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MIM_c04890 d28d748bfd8354aa3e112d63c6b08657 267 Pfam PF00977 Histidine biosynthesis protein 14 247 2.1E-87 T 12-10-2018 IPR006062 Histidine biosynthesis GO:0000105 MIM_c04890 d28d748bfd8354aa3e112d63c6b08657 267 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 11 264 5.5E-110 T 12-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 MIM_c04890 d28d748bfd8354aa3e112d63c6b08657 267 Gene3D G3DSA:3.20.20.70 9 267 1.5E-105 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c18910 f7e4e169b78ee8f01a78dbb40015d5dd 248 Gene3D G3DSA:3.30.230.70 20 247 1.9E-59 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MIM_c18910 f7e4e169b78ee8f01a78dbb40015d5dd 248 Pfam PF03725 3' exoribonuclease family, domain 2 169 234 8.0E-12 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MIM_c18910 f7e4e169b78ee8f01a78dbb40015d5dd 248 Pfam PF01138 3' exoribonuclease family, domain 1 21 150 4.3E-19 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MIM_c18910 f7e4e169b78ee8f01a78dbb40015d5dd 248 Hamap MF_00564 Ribonuclease PH [rph]. 21 247 44.703 T 12-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 MIM_c18910 f7e4e169b78ee8f01a78dbb40015d5dd 248 SUPERFAMILY SSF55666 162 245 9.03E-25 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MIM_c18910 f7e4e169b78ee8f01a78dbb40015d5dd 248 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 12 245 1.4E-114 T 12-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 MIM_c18910 f7e4e169b78ee8f01a78dbb40015d5dd 248 SUPERFAMILY SSF54211 11 191 5.57E-43 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MIM_c18910 f7e4e169b78ee8f01a78dbb40015d5dd 248 ProSitePatterns PS01277 Ribonuclease PH signature. 126 138 - T 12-10-2018 IPR018336 Ribonuclease PH, conserved site MIM_c36840 b423be914c169c74f151c1f214478d53 309 Pfam PF02535 ZIP Zinc transporter 166 304 9.1E-27 T 12-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 MIM_c30270 6bcfe3db15f5bb0544bd3c7309a97b62 163 SMART SM00347 33 134 1.7E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c30270 6bcfe3db15f5bb0544bd3c7309a97b62 163 Pfam PF12802 MarR family 55 98 3.8E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c30270 6bcfe3db15f5bb0544bd3c7309a97b62 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 5.1E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c30270 6bcfe3db15f5bb0544bd3c7309a97b62 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 5.1E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c30270 6bcfe3db15f5bb0544bd3c7309a97b62 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 124 144 5.1E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c30270 6bcfe3db15f5bb0544bd3c7309a97b62 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 5.1E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c30270 6bcfe3db15f5bb0544bd3c7309a97b62 163 Gene3D G3DSA:1.10.10.10 16 154 4.4E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c30270 6bcfe3db15f5bb0544bd3c7309a97b62 163 SUPERFAMILY SSF46785 14 149 2.11E-29 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c30150 7788b4634b0729afa8680663cde8e09d 481 PIRSF PIRSF006446 1 462 2.4E-215 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MIM_c30150 7788b4634b0729afa8680663cde8e09d 481 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 8 437 1.0E-165 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MIM_c25240 0ae87ed5aa2ebaa5ef138a07f57c7ebf 230 Pfam PF04172 LrgB-like family 14 225 6.5E-62 T 12-10-2018 IPR007300 CidB/LrgB family MIM_c04550 84bca26b861a9dcf1c056a09cec14939 74 Pfam PF11174 Protein of unknown function (DUF2970) 15 69 2.5E-23 T 12-10-2018 IPR021344 Protein of unknown function DUF2970 MIM_c00060 b54b4391f5126fa8a8e29d0503c9a4c7 1022 SUPERFAMILY SSF51126 262 613 2.13E-16 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor MIM_c00060 b54b4391f5126fa8a8e29d0503c9a4c7 1022 Pfam PF03797 Autotransporter beta-domain 753 1002 9.2E-61 T 12-10-2018 IPR005546 Autotransporter beta-domain MIM_c00060 b54b4391f5126fa8a8e29d0503c9a4c7 1022 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 542 1022 3.2E-54 T 12-10-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 MIM_c00060 b54b4391f5126fa8a8e29d0503c9a4c7 1022 PRINTS PR00723 Subtilisin serine protease family (S8) signature 107 120 1.7E-17 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related MIM_c00060 b54b4391f5126fa8a8e29d0503c9a4c7 1022 PRINTS PR00723 Subtilisin serine protease family (S8) signature 376 392 1.7E-17 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related MIM_c00060 b54b4391f5126fa8a8e29d0503c9a4c7 1022 PRINTS PR00723 Subtilisin serine protease family (S8) signature 58 77 1.7E-17 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related MIM_c00060 b54b4391f5126fa8a8e29d0503c9a4c7 1022 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 111 121 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site MIM_c00060 b54b4391f5126fa8a8e29d0503c9a4c7 1022 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 468 497 1.6E-9 T 12-10-2018 IPR013425 Autotransporter-associated beta strand repeat MIM_c00060 b54b4391f5126fa8a8e29d0503c9a4c7 1022 Gene3D G3DSA:2.40.128.130 685 1022 1.2E-73 T 12-10-2018 IPR036709 Autotransporter beta-domain superfamily MIM_c00060 b54b4391f5126fa8a8e29d0503c9a4c7 1022 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 63 74 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site MIM_c00060 b54b4391f5126fa8a8e29d0503c9a4c7 1022 Pfam PF00082 Subtilase family 58 422 1.3E-36 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MIM_c00060 b54b4391f5126fa8a8e29d0503c9a4c7 1022 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 377 387 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site MIM_c00060 b54b4391f5126fa8a8e29d0503c9a4c7 1022 SUPERFAMILY SSF103515 693 1022 3.53E-66 T 12-10-2018 IPR036709 Autotransporter beta-domain superfamily MIM_c00060 b54b4391f5126fa8a8e29d0503c9a4c7 1022 SUPERFAMILY SSF52743 39 439 5.89E-60 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 MIM_c00060 b54b4391f5126fa8a8e29d0503c9a4c7 1022 SMART SM00869 750 1012 1.2E-51 T 12-10-2018 IPR005546 Autotransporter beta-domain MIM_c00060 b54b4391f5126fa8a8e29d0503c9a4c7 1022 Pfam PF12951 Passenger-associated-transport-repeat 468 495 1.3E-6 T 12-10-2018 IPR013425 Autotransporter-associated beta strand repeat MIM_c19010 67d32394362eeb57b35390fdef60519a 682 SMART SM00487 255 449 7.3E-29 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MIM_c19010 67d32394362eeb57b35390fdef60519a 682 Gene3D G3DSA:2.40.50.140 41 132 3.2E-7 T 12-10-2018 MIM_c19010 67d32394362eeb57b35390fdef60519a 682 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 28 654 3.2E-210 T 12-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 MIM_c19010 67d32394362eeb57b35390fdef60519a 682 Gene3D G3DSA:3.40.50.300 447 619 7.7E-55 T 12-10-2018 MIM_c19010 67d32394362eeb57b35390fdef60519a 682 SMART SM00490 495 578 4.9E-20 T 12-10-2018 IPR001650 Helicase, C-terminal MIM_c19010 67d32394362eeb57b35390fdef60519a 682 Pfam PF00270 DEAD/DEAH box helicase 260 423 1.1E-17 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MIM_c19010 67d32394362eeb57b35390fdef60519a 682 SUPERFAMILY SSF52540 168 443 2.65E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c19010 67d32394362eeb57b35390fdef60519a 682 SUPERFAMILY SSF50249 15 164 2.66E-25 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c19010 67d32394362eeb57b35390fdef60519a 682 Pfam PF00271 Helicase conserved C-terminal domain 469 577 2.1E-17 T 12-10-2018 IPR001650 Helicase, C-terminal MIM_c19010 67d32394362eeb57b35390fdef60519a 682 Gene3D G3DSA:3.40.50.300 202 440 1.2E-81 T 12-10-2018 MIM_c19010 67d32394362eeb57b35390fdef60519a 682 SUPERFAMILY SSF52540 378 588 3.37E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c19010 67d32394362eeb57b35390fdef60519a 682 Pfam PF17191 RecG wedge domain 17 163 5.5E-14 T 12-10-2018 IPR033454 RecG, wedge domain MIM_c07390 96c0ca519bab5f62cfba7eb556cb0993 250 PIRSF PIRSF000709 127 239 0.096 T 12-10-2018 MIM_c07390 96c0ca519bab5f62cfba7eb556cb0993 250 PIRSF PIRSF000709 3 112 2.2E-8 T 12-10-2018 MIM_c07390 96c0ca519bab5f62cfba7eb556cb0993 250 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 12-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 MIM_c07390 96c0ca519bab5f62cfba7eb556cb0993 250 Gene3D G3DSA:3.40.50.1240 1 248 1.0E-90 T 12-10-2018 IPR029033 Histidine phosphatase superfamily MIM_c07390 96c0ca519bab5f62cfba7eb556cb0993 250 SUPERFAMILY SSF53254 1 245 1.83E-77 T 12-10-2018 IPR029033 Histidine phosphatase superfamily MIM_c07390 96c0ca519bab5f62cfba7eb556cb0993 250 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 137 4.6E-29 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MIM_c07390 96c0ca519bab5f62cfba7eb556cb0993 250 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 228 45.03 T 12-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 MIM_c07390 96c0ca519bab5f62cfba7eb556cb0993 250 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 3 246 1.6E-118 T 12-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 MIM_c07390 96c0ca519bab5f62cfba7eb556cb0993 250 SMART SM00855 3 189 3.5E-26 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MIM_c28000 4075ef1008f1a121ebda0745cc27d0f0 158 SUPERFAMILY SSF55486 25 155 1.83E-39 T 12-10-2018 MIM_c28000 4075ef1008f1a121ebda0745cc27d0f0 158 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 14 153 22.153 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MIM_c28000 4075ef1008f1a121ebda0745cc27d0f0 158 Gene3D G3DSA:3.40.390.30 7 158 3.6E-42 T 12-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 MIM_c28000 4075ef1008f1a121ebda0745cc27d0f0 158 Pfam PF02130 Uncharacterized protein family UPF0054 29 147 3.7E-32 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MIM_c28000 4075ef1008f1a121ebda0745cc27d0f0 158 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 47 149 5.4E-32 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MIM_c28000 4075ef1008f1a121ebda0745cc27d0f0 158 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 119 129 - T 12-10-2018 IPR020549 Endoribonuclease YbeY, conserved site MIM_c03940 57e9ba4c7ad0ee2824b55966f0d20430 458 Gene3D G3DSA:3.30.1540.10 101 189 6.3E-6 T 12-10-2018 MIM_c03940 57e9ba4c7ad0ee2824b55966f0d20430 458 Gene3D G3DSA:3.40.50.10540 209 432 2.4E-51 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c03940 57e9ba4c7ad0ee2824b55966f0d20430 458 Gene3D G3DSA:3.40.50.10540 53 196 6.3E-6 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c03940 57e9ba4c7ad0ee2824b55966f0d20430 458 Pfam PF02515 CoA-transferase family III 53 196 1.2E-6 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 MIM_c03940 57e9ba4c7ad0ee2824b55966f0d20430 458 Pfam PF02515 CoA-transferase family III 210 401 2.1E-39 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 MIM_c03940 57e9ba4c7ad0ee2824b55966f0d20430 458 SUPERFAMILY SSF89796 210 405 2.22E-53 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c03940 57e9ba4c7ad0ee2824b55966f0d20430 458 SUPERFAMILY SSF89796 40 201 2.62E-20 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c02900 9f8c098ad498f7e8055a310465fe65c0 283 SUPERFAMILY SSF52821 2 144 1.1E-41 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily MIM_c02900 9f8c098ad498f7e8055a310465fe65c0 283 SUPERFAMILY SSF52821 160 282 5.37E-29 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily MIM_c02900 9f8c098ad498f7e8055a310465fe65c0 283 Gene3D G3DSA:3.40.250.10 162 283 7.4E-31 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily MIM_c02900 9f8c098ad498f7e8055a310465fe65c0 283 Gene3D G3DSA:3.40.250.10 1 149 5.4E-50 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily MIM_c02900 9f8c098ad498f7e8055a310465fe65c0 283 Pfam PF00581 Rhodanese-like domain 8 129 1.6E-18 T 12-10-2018 IPR001763 Rhodanese-like domain MIM_c02900 9f8c098ad498f7e8055a310465fe65c0 283 Pfam PF00581 Rhodanese-like domain 161 274 1.8E-8 T 12-10-2018 IPR001763 Rhodanese-like domain MIM_c02900 9f8c098ad498f7e8055a310465fe65c0 283 SMART SM00450 158 278 3.9E-11 T 12-10-2018 IPR001763 Rhodanese-like domain MIM_c02900 9f8c098ad498f7e8055a310465fe65c0 283 SMART SM00450 8 134 6.7E-18 T 12-10-2018 IPR001763 Rhodanese-like domain MIM_c02900 9f8c098ad498f7e8055a310465fe65c0 283 ProSitePatterns PS00380 Rhodanese signature 1. 41 52 - T 12-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 MIM_c01620 d2d7f62856480fa483ed75cf41290d09 249 PIRSF PIRSF015736 1 249 1.3E-60 T 12-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase MIM_c01620 d2d7f62856480fa483ed75cf41290d09 249 Pfam PF01177 Asp/Glu/Hydantoin racemase 6 228 4.2E-9 T 12-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MIM_c01620 d2d7f62856480fa483ed75cf41290d09 249 Hamap MF_00943 Maleate isomerase [maiA]. 4 249 48.067 T 12-10-2018 IPR028615 Maleate isomerase GO:0050076 KEGG: 00650+5.2.1.1|KEGG: 00760+5.2.1.1|MetaCyc: PWY-5033|MetaCyc: PWY-6993|MetaCyc: PWY-7128|MetaCyc: PWY-722 MIM_c01620 d2d7f62856480fa483ed75cf41290d09 249 Gene3D G3DSA:3.40.50.12500 4 249 5.2E-78 T 12-10-2018 MIM_c22600 f09e0a3b7241f793d71994c8a1e4ff2f 329 Gene3D G3DSA:3.40.190.10 130 254 6.3E-85 T 12-10-2018 MIM_c22600 f09e0a3b7241f793d71994c8a1e4ff2f 329 Gene3D G3DSA:3.40.190.150 33 318 6.3E-85 T 12-10-2018 MIM_c22600 f09e0a3b7241f793d71994c8a1e4ff2f 329 PIRSF PIRSF017082 2 329 1.4E-66 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c22600 f09e0a3b7241f793d71994c8a1e4ff2f 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 326 9.6E-67 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c09230 3ec0a6858c4830cf75267537839aad01 406 Gene3D G3DSA:2.40.50.100 100 244 1.3E-68 T 12-10-2018 MIM_c09230 3ec0a6858c4830cf75267537839aad01 406 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 76 404 5.7E-79 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MIM_c09230 3ec0a6858c4830cf75267537839aad01 406 Gene3D G3DSA:1.10.287.470 135 208 1.3E-68 T 12-10-2018 MIM_c09230 3ec0a6858c4830cf75267537839aad01 406 Pfam PF13437 HlyD family secretion protein 211 314 2.6E-8 T 12-10-2018 MIM_c09230 3ec0a6858c4830cf75267537839aad01 406 Pfam PF13533 Biotin-lipoyl like 101 149 1.2E-13 T 12-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain MIM_c09230 3ec0a6858c4830cf75267537839aad01 406 SUPERFAMILY SSF111369 91 328 2.75E-59 T 12-10-2018 MIM_c09230 3ec0a6858c4830cf75267537839aad01 406 Gene3D G3DSA:2.40.30.170 94 312 1.3E-68 T 12-10-2018 MIM_c09230 3ec0a6858c4830cf75267537839aad01 406 Gene3D G3DSA:2.40.420.20 313 405 1.1E-21 T 12-10-2018 MIM_c23330 cfb74090b3485b7ac0be050c595cfb06 195 SUPERFAMILY SSF52374 1 194 4.38E-49 T 12-10-2018 MIM_c23330 cfb74090b3485b7ac0be050c595cfb06 195 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 66 8.2E-8 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MIM_c23330 cfb74090b3485b7ac0be050c595cfb06 195 Gene3D G3DSA:3.40.50.620 1 195 4.6E-61 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c23330 cfb74090b3485b7ac0be050c595cfb06 195 Pfam PF01467 Cytidylyltransferase-like 6 169 1.9E-28 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MIM_c23330 cfb74090b3485b7ac0be050c595cfb06 195 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 2 195 28.637 T 12-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MIM_c23330 cfb74090b3485b7ac0be050c595cfb06 195 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 6 194 6.3E-50 T 12-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MIM_c09290 b8ae596ba82c3e663e00c84ef003ed2f 306 SUPERFAMILY SSF52540 49 198 1.7E-26 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c09290 b8ae596ba82c3e663e00c84ef003ed2f 306 Gene3D G3DSA:3.40.50.300 59 198 1.6E-10 T 12-10-2018 MIM_c09290 b8ae596ba82c3e663e00c84ef003ed2f 306 Pfam PF05673 Protein of unknown function (DUF815) 39 290 2.0E-103 T 12-10-2018 IPR008533 Domain of unknown function DUF815 MIM_c22330 52caf3e517fc46958996393a817d163c 215 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 29 197 1.0E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c22330 52caf3e517fc46958996393a817d163c 215 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 6 104 4.2E-22 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c22330 52caf3e517fc46958996393a817d163c 215 SUPERFAMILY SSF161098 9 196 3.53E-39 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c22330 52caf3e517fc46958996393a817d163c 215 Gene3D G3DSA:1.10.3720.10 2 212 2.5E-44 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c27190 51b16280f01fa80fc2aba0bebc41ede1 319 Gene3D G3DSA:3.40.50.300 140 318 2.2E-39 T 12-10-2018 MIM_c27190 51b16280f01fa80fc2aba0bebc41ede1 319 Gene3D G3DSA:1.10.260.40 34 118 4.8E-15 T 12-10-2018 MIM_c27190 51b16280f01fa80fc2aba0bebc41ede1 319 SUPERFAMILY SSF52540 144 305 6.19E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c27190 51b16280f01fa80fc2aba0bebc41ede1 319 Hamap MF_00109 Shikimate kinase [aroK]. 142 309 20.661 T 12-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MIM_c27190 51b16280f01fa80fc2aba0bebc41ede1 319 Pfam PF13560 Helix-turn-helix domain 36 94 2.6E-8 T 12-10-2018 MIM_c27190 51b16280f01fa80fc2aba0bebc41ede1 319 SUPERFAMILY SSF47413 28 100 6.19E-14 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c27190 51b16280f01fa80fc2aba0bebc41ede1 319 Pfam PF01202 Shikimate kinase 151 307 2.9E-32 T 12-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MIM_c27190 51b16280f01fa80fc2aba0bebc41ede1 319 PRINTS PR01100 Shikimate kinase family signature 197 205 2.6E-12 T 12-10-2018 MIM_c27190 51b16280f01fa80fc2aba0bebc41ede1 319 PRINTS PR01100 Shikimate kinase family signature 216 225 2.6E-12 T 12-10-2018 MIM_c27190 51b16280f01fa80fc2aba0bebc41ede1 319 PRINTS PR01100 Shikimate kinase family signature 145 160 2.6E-12 T 12-10-2018 MIM_c27190 51b16280f01fa80fc2aba0bebc41ede1 319 PRINTS PR01100 Shikimate kinase family signature 169 182 2.6E-12 T 12-10-2018 MIM_c27190 51b16280f01fa80fc2aba0bebc41ede1 319 SMART SM00530 40 95 2.3E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c39780 71854b5aadbedab924869ea39d39ecb4 334 Gene3D G3DSA:3.40.50.2300 28 308 8.7E-104 T 12-10-2018 MIM_c39780 71854b5aadbedab924869ea39d39ecb4 334 SUPERFAMILY SSF53822 28 334 1.37E-67 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c39780 71854b5aadbedab924869ea39d39ecb4 334 Pfam PF13407 Periplasmic binding protein domain 31 288 8.1E-50 T 12-10-2018 IPR025997 Periplasmic binding protein MIM_c39780 71854b5aadbedab924869ea39d39ecb4 334 Gene3D G3DSA:3.40.50.2300 133 268 8.7E-104 T 12-10-2018 MIM_c33100 df41762d889ae721b5997178fb3d032b 202 Gene3D G3DSA:3.40.50.150 46 190 9.0E-15 T 12-10-2018 MIM_c33100 df41762d889ae721b5997178fb3d032b 202 SMART SM00650 46 165 0.0059 T 12-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 MIM_c33100 df41762d889ae721b5997178fb3d032b 202 Pfam PF13649 Methyltransferase domain 62 158 2.2E-8 T 12-10-2018 MIM_c33100 df41762d889ae721b5997178fb3d032b 202 SUPERFAMILY SSF53335 42 175 2.18E-22 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c06990 7a7f87ba0f3e6e98cb7e4a76094489eb 230 Pfam PF01168 Alanine racemase, N-terminal domain 8 227 5.4E-29 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MIM_c06990 7a7f87ba0f3e6e98cb7e4a76094489eb 230 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 4 226 4.2E-53 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 MIM_c06990 7a7f87ba0f3e6e98cb7e4a76094489eb 230 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 5 225 27.663 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 MIM_c06990 7a7f87ba0f3e6e98cb7e4a76094489eb 230 Gene3D G3DSA:3.20.20.10 1 229 1.0E-80 T 12-10-2018 IPR029066 PLP-binding barrel MIM_c06990 7a7f87ba0f3e6e98cb7e4a76094489eb 230 SUPERFAMILY SSF51419 1 224 7.59E-69 T 12-10-2018 IPR029066 PLP-binding barrel MIM_c06990 7a7f87ba0f3e6e98cb7e4a76094489eb 230 PIRSF PIRSF004848 1 230 2.3E-69 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 MIM_c32580 d39cd2f2ffc349e295dff3f735a3089b 424 PIRSF PIRSF000124 6 422 6.5E-51 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MIM_c32580 d39cd2f2ffc349e295dff3f735a3089b 424 Gene3D G3DSA:3.40.50.720 201 423 1.1E-54 T 12-10-2018 MIM_c32580 d39cd2f2ffc349e295dff3f735a3089b 424 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 202 290 7.4E-24 T 12-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MIM_c32580 d39cd2f2ffc349e295dff3f735a3089b 424 SUPERFAMILY SSF48179 200 292 6.29E-25 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c32580 d39cd2f2ffc349e295dff3f735a3089b 424 SUPERFAMILY SSF52413 300 416 1.26E-27 T 12-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 MIM_c32580 d39cd2f2ffc349e295dff3f735a3089b 424 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 7 410 5.3E-121 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MIM_c32580 d39cd2f2ffc349e295dff3f735a3089b 424 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 7 180 3.0E-33 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MIM_c32580 d39cd2f2ffc349e295dff3f735a3089b 424 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 317 416 1.1E-18 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MIM_c32580 d39cd2f2ffc349e295dff3f735a3089b 424 PIRSF PIRSF500136 2 424 1.1E-150 T 12-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 MIM_c32580 d39cd2f2ffc349e295dff3f735a3089b 424 SMART SM00984 317 417 1.1E-33 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MIM_c32580 d39cd2f2ffc349e295dff3f735a3089b 424 Gene3D G3DSA:3.40.50.720 3 198 1.4E-58 T 12-10-2018 MIM_c32580 d39cd2f2ffc349e295dff3f735a3089b 424 SUPERFAMILY SSF51735 7 191 2.86E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c29160 a880f32a10b1416887f3afcc83f307e6 101 TIGRFAM TIGR02684 dnstrm_HI1420: probable addiction module antidote protein 4 90 1.4E-34 T 12-10-2018 IPR014057 Uncharacterized protein HI1420 MIM_c29160 a880f32a10b1416887f3afcc83f307e6 101 SUPERFAMILY SSF47413 29 89 1.45E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c02540 7cba0690bab44127663df0d64274c947 142 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 11 138 7.6E-44 T 12-10-2018 IPR001602 Uncharacterised protein family UPF0047 MIM_c02540 7cba0690bab44127663df0d64274c947 142 PIRSF PIRSF004681 1 139 5.1E-46 T 12-10-2018 IPR001602 Uncharacterised protein family UPF0047 MIM_c02540 7cba0690bab44127663df0d64274c947 142 SUPERFAMILY SSF111038 1 138 1.44E-48 T 12-10-2018 IPR035917 YjbQ-like superfamily MIM_c02540 7cba0690bab44127663df0d64274c947 142 Pfam PF01894 Uncharacterised protein family UPF0047 19 135 1.2E-39 T 12-10-2018 IPR001602 Uncharacterised protein family UPF0047 MIM_c02540 7cba0690bab44127663df0d64274c947 142 Gene3D G3DSA:2.60.120.460 2 139 3.1E-42 T 12-10-2018 IPR035917 YjbQ-like superfamily MIM_c04680 a0980c2031d5f48dcb990b5eb72a4907 283 SUPERFAMILY SSF53474 5 283 7.44E-84 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c04680 a0980c2031d5f48dcb990b5eb72a4907 283 Pfam PF00756 Putative esterase 25 277 1.5E-51 T 12-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 MIM_c04680 a0980c2031d5f48dcb990b5eb72a4907 283 Gene3D G3DSA:3.40.50.1820 5 283 1.9E-83 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c04680 a0980c2031d5f48dcb990b5eb72a4907 283 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 6 282 1.5E-130 T 12-10-2018 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 MIM_c14340 f81a904ed27099f0a1c1cd8a8ace5fac 293 PRINTS PR00478 Phosphoribulokinase family signature 127 145 1.7E-33 T 12-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 MIM_c14340 f81a904ed27099f0a1c1cd8a8ace5fac 293 PRINTS PR00478 Phosphoribulokinase family signature 183 206 1.7E-33 T 12-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 MIM_c14340 f81a904ed27099f0a1c1cd8a8ace5fac 293 PRINTS PR00478 Phosphoribulokinase family signature 12 29 1.7E-33 T 12-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 MIM_c14340 f81a904ed27099f0a1c1cd8a8ace5fac 293 PRINTS PR00478 Phosphoribulokinase family signature 165 182 1.7E-33 T 12-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 MIM_c14340 f81a904ed27099f0a1c1cd8a8ace5fac 293 ProSitePatterns PS00567 Phosphoribulokinase signature. 165 178 - T 12-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 MIM_c14340 f81a904ed27099f0a1c1cd8a8ace5fac 293 Gene3D G3DSA:3.40.50.300 1 290 7.3E-119 T 12-10-2018 MIM_c14340 f81a904ed27099f0a1c1cd8a8ace5fac 293 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 215 4.3E-76 T 12-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 MIM_c14340 f81a904ed27099f0a1c1cd8a8ace5fac 293 SUPERFAMILY SSF52540 3 287 2.21E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c27460 960d5b4c137d81bd4ba1e33da2b004e6 141 Gene3D G3DSA:2.60.120.10 17 140 1.3E-40 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c27460 960d5b4c137d81bd4ba1e33da2b004e6 141 SUPERFAMILY SSF51182 34 135 2.06E-17 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c27460 960d5b4c137d81bd4ba1e33da2b004e6 141 Pfam PF07883 Cupin domain 63 127 5.1E-10 T 12-10-2018 IPR013096 Cupin 2, conserved barrel MIM_c41140 1d3e284742e4063b39c322cd046492bd 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 324 7.8E-82 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c41140 1d3e284742e4063b39c322cd046492bd 328 SUPERFAMILY SSF53850 118 288 1.14E-11 T 12-10-2018 MIM_c41140 1d3e284742e4063b39c322cd046492bd 328 Gene3D G3DSA:3.40.190.150 33 318 2.2E-104 T 12-10-2018 MIM_c41140 1d3e284742e4063b39c322cd046492bd 328 PIRSF PIRSF017082 2 328 4.5E-71 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c41140 1d3e284742e4063b39c322cd046492bd 328 Gene3D G3DSA:3.40.190.10 131 253 2.2E-104 T 12-10-2018 MIM_c21160 3cd635b080eae927def2daabc94a9dad 113 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 109 6.7E-28 T 12-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like MIM_c03860 d66926d97fa463fa4fab7dc0f0ca747e 244 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 42 235 2.4E-13 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c03860 d66926d97fa463fa4fab7dc0f0ca747e 244 SUPERFAMILY SSF161098 24 232 3.53E-35 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c03860 d66926d97fa463fa4fab7dc0f0ca747e 244 Gene3D G3DSA:1.10.3720.10 15 236 5.7E-42 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c03860 d66926d97fa463fa4fab7dc0f0ca747e 244 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 27 129 1.0E-15 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c20430 75a6f74fac69bf61ade51665388dc148 350 Pfam PF04909 Amidohydrolase 37 348 1.1E-26 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MIM_c20430 75a6f74fac69bf61ade51665388dc148 350 SUPERFAMILY SSF51556 35 349 8.17E-31 T 12-10-2018 IPR032466 Metal-dependent hydrolase MIM_c20430 75a6f74fac69bf61ade51665388dc148 350 Gene3D G3DSA:3.20.20.140 34 350 5.1E-68 T 12-10-2018 MIM_c18760 e103ae83c1c155bd78b270e9c259d22d 272 Gene3D G3DSA:3.20.20.140 1 261 1.7E-71 T 12-10-2018 MIM_c18760 e103ae83c1c155bd78b270e9c259d22d 272 PIRSF PIRSF005902 1 263 3.1E-61 T 12-10-2018 IPR001130 TatD family GO:0016788 MIM_c18760 e103ae83c1c155bd78b270e9c259d22d 272 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 12-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 MIM_c18760 e103ae83c1c155bd78b270e9c259d22d 272 SUPERFAMILY SSF51556 2 260 3.24E-70 T 12-10-2018 IPR032466 Metal-dependent hydrolase MIM_c18760 e103ae83c1c155bd78b270e9c259d22d 272 Pfam PF01026 TatD related DNase 3 259 3.2E-60 T 12-10-2018 IPR001130 TatD family GO:0016788 MIM_c14320 49452116d26d1b8572fa7f5871de3c5f 351 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 328 3.2E-93 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MIM_c14320 49452116d26d1b8572fa7f5871de3c5f 351 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 329 3.3E-96 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MIM_c14320 49452116d26d1b8572fa7f5871de3c5f 351 Gene3D G3DSA:3.20.20.70 1 351 3.4E-144 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c14320 49452116d26d1b8572fa7f5871de3c5f 351 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 139 150 - T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MIM_c14320 49452116d26d1b8572fa7f5871de3c5f 351 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 73 85 - T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MIM_c14320 49452116d26d1b8572fa7f5871de3c5f 351 PIRSF PIRSF001359 1 329 1.7E-81 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MIM_c14320 49452116d26d1b8572fa7f5871de3c5f 351 SUPERFAMILY SSF51569 1 329 3.52E-104 T 12-10-2018 MIM_c14320 49452116d26d1b8572fa7f5871de3c5f 351 TIGRFAM TIGR01521 FruBisAldo_II_B: fructose-bisphosphate aldolase, class II, Calvin cycle subtype 3 346 1.6E-188 T 12-10-2018 IPR006412 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 MIM_c04160 a537b4d8a87024b5d20d4fb29093214b 259 Gene3D G3DSA:1.20.1290.10 35 255 1.4E-49 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c04160 a537b4d8a87024b5d20d4fb29093214b 259 Pfam PF02627 Carboxymuconolactone decarboxylase family 173 251 1.1E-10 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c04160 a537b4d8a87024b5d20d4fb29093214b 259 Pfam PF02627 Carboxymuconolactone decarboxylase family 47 111 1.3E-4 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c04160 a537b4d8a87024b5d20d4fb29093214b 259 SUPERFAMILY SSF69118 43 251 1.88E-38 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c05470 f95ebe7e99171210451109fb82adcec0 234 Pfam PF04972 BON domain 57 123 1.8E-12 T 12-10-2018 IPR007055 BON domain MIM_c05470 f95ebe7e99171210451109fb82adcec0 234 Pfam PF04972 BON domain 132 197 8.7E-15 T 12-10-2018 IPR007055 BON domain MIM_c05470 f95ebe7e99171210451109fb82adcec0 234 SMART SM00749 59 122 17.0 T 12-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria MIM_c05470 f95ebe7e99171210451109fb82adcec0 234 SMART SM00749 137 200 1.1E-9 T 12-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria MIM_c06500 cb931d09ab7561c776c2bda0a57beb93 175 TIGRFAM TIGR03352 VI_chp_3: type VI secretion lipoprotein, VC_A0113 family 14 164 7.4E-41 T 12-10-2018 IPR017734 Type VI secretion system, lipoprotein SciN MIM_c06500 cb931d09ab7561c776c2bda0a57beb93 175 Pfam PF12790 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 21 155 8.8E-39 T 12-10-2018 IPR017734 Type VI secretion system, lipoprotein SciN MIM_c06500 cb931d09ab7561c776c2bda0a57beb93 175 Gene3D G3DSA:2.60.40.4150 28 173 1.3E-46 T 12-10-2018 IPR038706 Type VI secretion protein SciN-like superfamily MIM_c18490 ac5fc9f73f8fc04bec67159beda40427 255 PIRSF PIRSF000386 1 251 7.5E-87 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MIM_c18490 ac5fc9f73f8fc04bec67159beda40427 255 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 228 6.9E-55 T 12-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MIM_c18490 ac5fc9f73f8fc04bec67159beda40427 255 SUPERFAMILY SSF75217 1 237 5.69E-89 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases MIM_c18490 ac5fc9f73f8fc04bec67159beda40427 255 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 255 103.231 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MIM_c18490 ac5fc9f73f8fc04bec67159beda40427 255 Gene3D G3DSA:3.40.1280.10 1 176 1.0E-63 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MIM_c18490 ac5fc9f73f8fc04bec67159beda40427 255 Gene3D G3DSA:1.10.1270.20 177 255 1.1E-26 T 12-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MIM_c18490 ac5fc9f73f8fc04bec67159beda40427 255 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 234 6.0E-83 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MIM_c38070 156c35e6821ca9c40aec1ceec44d3dae 498 TIGRFAM TIGR03355 VI_chp_2: type VI secretion protein, EvpB/VC_A0108 family 18 491 3.4E-227 T 12-10-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath MIM_c38070 156c35e6821ca9c40aec1ceec44d3dae 498 Pfam PF05943 Type VI secretion protein, EvpB/VC_A0108, tail sheath 67 491 2.2E-193 T 12-10-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath MIM_c03180 0af2e0fa5ed2edad8de1a913ad60e95f 129 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 3 122 1.6E-40 T 12-10-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system MIM_c03180 0af2e0fa5ed2edad8de1a913ad60e95f 129 SUPERFAMILY SSF143100 1 60 1.29E-13 T 12-10-2018 IPR035069 TTHA1013/TTHA0281-like MIM_c03180 0af2e0fa5ed2edad8de1a913ad60e95f 129 Gene3D G3DSA:3.30.160.250 1 81 1.6E-19 T 12-10-2018 MIM_c03180 0af2e0fa5ed2edad8de1a913ad60e95f 129 SUPERFAMILY SSF47598 89 124 1.2E-5 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 MIM_c15470 e8bc6ee94b128e6e4916b6840819efa1 264 Gene3D G3DSA:3.40.50.620 25 264 4.6E-62 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c15470 e8bc6ee94b128e6e4916b6840819efa1 264 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 55 236 1.3E-35 T 12-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 MIM_c15470 e8bc6ee94b128e6e4916b6840819efa1 264 SUPERFAMILY SSF52402 31 224 1.18E-39 T 12-10-2018 MIM_c15470 e8bc6ee94b128e6e4916b6840819efa1 264 PIRSF PIRSF000857 6 264 2.2E-74 T 12-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 MIM_c15470 e8bc6ee94b128e6e4916b6840819efa1 264 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 57 260 4.1E-76 T 12-10-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 MIM_c12630 37082af6099af9e8ba1b3aa02f4e58c6 229 Pfam PF13417 Glutathione S-transferase, N-terminal domain 6 77 7.6E-15 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MIM_c12630 37082af6099af9e8ba1b3aa02f4e58c6 229 Gene3D G3DSA:3.40.30.10 2 74 2.7E-15 T 12-10-2018 MIM_c12630 37082af6099af9e8ba1b3aa02f4e58c6 229 Pfam PF13410 Glutathione S-transferase, C-terminal domain 125 186 7.1E-8 T 12-10-2018 MIM_c12630 37082af6099af9e8ba1b3aa02f4e58c6 229 SUPERFAMILY SSF52833 5 89 5.71E-18 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c12630 37082af6099af9e8ba1b3aa02f4e58c6 229 Gene3D G3DSA:1.20.1050.10 75 194 2.9E-10 T 12-10-2018 MIM_c12630 37082af6099af9e8ba1b3aa02f4e58c6 229 SUPERFAMILY SSF47616 82 206 2.78E-17 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MIM_c28820 6da10f2964552544945ca9e2c8807ee5 334 SUPERFAMILY SSF53850 120 294 1.11E-10 T 12-10-2018 MIM_c28820 6da10f2964552544945ca9e2c8807ee5 334 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 330 3.2E-73 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c28820 6da10f2964552544945ca9e2c8807ee5 334 PIRSF PIRSF017082 2 333 9.6E-73 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c28820 6da10f2964552544945ca9e2c8807ee5 334 Gene3D G3DSA:3.40.190.150 37 324 1.3E-103 T 12-10-2018 MIM_c28820 6da10f2964552544945ca9e2c8807ee5 334 Gene3D G3DSA:3.40.190.10 136 259 1.3E-103 T 12-10-2018 MIM_c25200 0a14afd156ac77c990e3811f06c7a223 91 Pfam PF05015 RelE-like toxin of type II toxin-antitoxin system HigB 3 91 3.2E-17 T 12-10-2018 IPR007711 Toxin HigB-1 MIM_c25200 0a14afd156ac77c990e3811f06c7a223 91 SUPERFAMILY SSF143011 1 91 3.66E-13 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MIM_c25200 0a14afd156ac77c990e3811f06c7a223 91 Gene3D G3DSA:3.30.2310.20 1 91 2.2E-32 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MIM_c17390 1cb4a1f5043bc325cfd78bbf3dbd6570 501 SUPERFAMILY SSF51338 15 470 1.91E-34 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MIM_c17390 1cb4a1f5043bc325cfd78bbf3dbd6570 501 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 18 471 1.3E-163 T 12-10-2018 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 MIM_c17390 1cb4a1f5043bc325cfd78bbf3dbd6570 501 Gene3D G3DSA:3.20.20.140 66 440 8.0E-163 T 12-10-2018 MIM_c17390 1cb4a1f5043bc325cfd78bbf3dbd6570 501 SUPERFAMILY SSF51556 66 399 1.21E-91 T 12-10-2018 IPR032466 Metal-dependent hydrolase MIM_c17390 1cb4a1f5043bc325cfd78bbf3dbd6570 501 Pfam PF01979 Amidohydrolase family 62 453 2.0E-26 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MIM_c17390 1cb4a1f5043bc325cfd78bbf3dbd6570 501 Gene3D G3DSA:2.30.40.10 16 469 8.0E-163 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MIM_c20320 aa7b88bed055a8da55e13a07bbd703f3 539 PIRSF PIRSF000137 1 537 6.8E-154 T 12-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c20320 aa7b88bed055a8da55e13a07bbd703f3 539 SUPERFAMILY SSF54373 289 474 4.02E-48 T 12-10-2018 MIM_c20320 aa7b88bed055a8da55e13a07bbd703f3 539 SUPERFAMILY SSF51905 3 533 2.75E-85 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c20320 aa7b88bed055a8da55e13a07bbd703f3 539 Gene3D G3DSA:3.30.560.10 42 469 3.0E-171 T 12-10-2018 MIM_c20320 aa7b88bed055a8da55e13a07bbd703f3 539 Pfam PF05199 GMC oxidoreductase 388 523 4.9E-38 T 12-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 MIM_c20320 aa7b88bed055a8da55e13a07bbd703f3 539 Gene3D G3DSA:3.50.50.60 4 528 3.0E-171 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c20320 aa7b88bed055a8da55e13a07bbd703f3 539 Pfam PF00732 GMC oxidoreductase 5 294 4.7E-82 T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c12670 60c6a9f23b51b8eacb243f8376271b45 228 SMART SM00895 86 206 1.4E-15 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c12670 60c6a9f23b51b8eacb243f8376271b45 228 Gene3D G3DSA:1.20.120.530 84 220 2.4E-25 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c12670 60c6a9f23b51b8eacb243f8376271b45 228 SMART SM00345 18 76 5.2E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c12670 60c6a9f23b51b8eacb243f8376271b45 228 SUPERFAMILY SSF46785 6 102 2.56E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c12670 60c6a9f23b51b8eacb243f8376271b45 228 Gene3D G3DSA:1.10.10.10 13 77 4.7E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c12670 60c6a9f23b51b8eacb243f8376271b45 228 SUPERFAMILY SSF48008 87 213 4.71E-24 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c12670 60c6a9f23b51b8eacb243f8376271b45 228 Pfam PF07729 FCD domain 87 203 6.8E-21 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c12670 60c6a9f23b51b8eacb243f8376271b45 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 76 1.3E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c30290 958779f041b1cc147baaa725b36663e7 73 Pfam PF07869 Protein of unknown function (DUF1656) 4 58 2.8E-21 T 12-10-2018 IPR012451 Protein of unknown function DUF1656 MIM_c20240 3c56aef8bbae9860632b11f64aac55ab 477 SUPERFAMILY SSF103378 3 463 3.4E-89 T 12-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 MIM_c20240 3c56aef8bbae9860632b11f64aac55ab 477 Gene3D G3DSA:1.10.4100.10 1 317 1.1E-65 T 12-10-2018 MIM_c20240 3c56aef8bbae9860632b11f64aac55ab 477 Pfam PF03972 MmgE/PrpD family 6 456 5.3E-86 T 12-10-2018 IPR005656 MmgE/PrpD GO:0016829 MIM_c27340 cb2450d53bcd1308366970da93c623a3 218 SUPERFAMILY SSF53474 3 218 4.72E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c27340 cb2450d53bcd1308366970da93c623a3 218 Pfam PF01738 Dienelactone hydrolase family 14 216 2.1E-43 T 12-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 MIM_c27340 cb2450d53bcd1308366970da93c623a3 218 Gene3D G3DSA:3.40.50.1820 1 217 7.8E-52 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c00900 5f90af3fc8006ac316551b92a66bae2c 303 Gene3D G3DSA:1.10.10.10 6 92 2.3E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c00900 5f90af3fc8006ac316551b92a66bae2c 303 Gene3D G3DSA:3.40.190.10 167 266 1.4E-59 T 12-10-2018 MIM_c00900 5f90af3fc8006ac316551b92a66bae2c 303 SUPERFAMILY SSF53850 93 299 7.24E-40 T 12-10-2018 MIM_c00900 5f90af3fc8006ac316551b92a66bae2c 303 Pfam PF03466 LysR substrate binding domain 92 294 4.1E-38 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c00900 5f90af3fc8006ac316551b92a66bae2c 303 SUPERFAMILY SSF46785 5 116 1.94E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c00900 5f90af3fc8006ac316551b92a66bae2c 303 Gene3D G3DSA:3.40.190.10 95 292 1.4E-59 T 12-10-2018 MIM_c00900 5f90af3fc8006ac316551b92a66bae2c 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 6.6E-14 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c39850 f5e0b5803e3854cf427dd96d35fb7f95 239 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c39850 f5e0b5803e3854cf427dd96d35fb7f95 239 PIRSF PIRSF039137 2 239 8.7E-104 T 12-10-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 MIM_c39850 f5e0b5803e3854cf427dd96d35fb7f95 239 SUPERFAMILY SSF52540 5 237 1.49E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c39850 f5e0b5803e3854cf427dd96d35fb7f95 239 SMART SM00382 31 222 3.3E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c39850 f5e0b5803e3854cf427dd96d35fb7f95 239 Pfam PF00005 ABC transporter 22 166 1.4E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c39850 f5e0b5803e3854cf427dd96d35fb7f95 239 Gene3D G3DSA:3.40.50.300 2 239 3.6E-65 T 12-10-2018 MIM_c03900 017cea524997d678aa596f90e9c0c949 167 Pfam PF05981 CreA protein 30 157 1.3E-49 T 12-10-2018 IPR010292 Uncharacterised protein family CreA MIM_c03900 017cea524997d678aa596f90e9c0c949 167 PIRSF PIRSF003174 3 165 1.9E-54 T 12-10-2018 IPR010292 Uncharacterised protein family CreA MIM_c00780 f6bf6ff2dfc13067d92e777ba64a7771 352 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 274 289 8.3E-20 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MIM_c00780 f6bf6ff2dfc13067d92e777ba64a7771 352 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 10 32 8.3E-20 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MIM_c00780 f6bf6ff2dfc13067d92e777ba64a7771 352 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 230 247 8.3E-20 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MIM_c00780 f6bf6ff2dfc13067d92e777ba64a7771 352 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 210 228 8.3E-20 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MIM_c00780 f6bf6ff2dfc13067d92e777ba64a7771 352 SUPERFAMILY SSF160544 254 347 5.76E-10 T 12-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal MIM_c00780 f6bf6ff2dfc13067d92e777ba64a7771 352 Pfam PF01312 FlhB HrpN YscU SpaS Family 7 347 1.8E-88 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MIM_c00780 f6bf6ff2dfc13067d92e777ba64a7771 352 Gene3D G3DSA:3.40.1690.10 219 350 6.2E-26 T 12-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal MIM_c14140 d0f4d11178e2df3c861358ce3cfb3d07 252 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 31 181 2.2E-54 T 12-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 MIM_c14140 d0f4d11178e2df3c861358ce3cfb3d07 252 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 182 223 4.4E-15 T 12-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 MIM_c14140 d0f4d11178e2df3c861358ce3cfb3d07 252 Gene3D G3DSA:3.30.2350.10 1 239 3.4E-87 T 12-10-2018 MIM_c14140 d0f4d11178e2df3c861358ce3cfb3d07 252 SUPERFAMILY SSF55120 9 226 2.88E-76 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MIM_c14140 d0f4d11178e2df3c861358ce3cfb3d07 252 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 9 220 6.9E-76 T 12-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 MIM_c14140 d0f4d11178e2df3c861358ce3cfb3d07 252 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 9 246 17.792 T 12-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 MIM_c27230 faeebdf9e3e33f579ce42bea137810c5 289 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 277 4.0E-37 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c11370 d55d994ca4b3ebc2d749e2cec789b345 133 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 34 105 4.3E-16 T 12-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 MIM_c11370 d55d994ca4b3ebc2d749e2cec789b345 133 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 28 122 1.2E-31 T 12-10-2018 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 MIM_c27930 91e8c44b733a49365974254e24a3b79e 352 Pfam PF02547 Queuosine biosynthesis protein 11 349 3.1E-134 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 MIM_c27930 91e8c44b733a49365974254e24a3b79e 352 Gene3D G3DSA:3.40.1780.10 21 349 1.6E-115 T 12-10-2018 MIM_c27930 91e8c44b733a49365974254e24a3b79e 352 Gene3D G3DSA:2.40.10.240 70 165 1.6E-115 T 12-10-2018 MIM_c27930 91e8c44b733a49365974254e24a3b79e 352 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 8 350 46.588 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 MIM_c27930 91e8c44b733a49365974254e24a3b79e 352 SUPERFAMILY SSF111337 9 349 1.83E-131 T 12-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 MIM_c27930 91e8c44b733a49365974254e24a3b79e 352 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 9 349 2.3E-136 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 MIM_c33320 13eae8ef640c31c3621dbeb23319cfe3 295 Pfam PF14491 Protein of unknown function (DUF4435) 23 255 3.5E-14 T 12-10-2018 IPR029492 Domain of unknown function DUF4435 MIM_c12710 fe2dfaf53e3a7807193cb3ed4addaa65 266 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 258 1.1E-54 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c12710 fe2dfaf53e3a7807193cb3ed4addaa65 266 SUPERFAMILY SSF52096 1 262 6.07E-80 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c12710 fe2dfaf53e3a7807193cb3ed4addaa65 266 Gene3D G3DSA:1.10.12.10 210 260 1.2E-6 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MIM_c12710 fe2dfaf53e3a7807193cb3ed4addaa65 266 Gene3D G3DSA:3.90.226.10 1 207 2.8E-69 T 12-10-2018 MIM_c02950 65005008951f4de3f5ca27faab30fcec 305 SUPERFAMILY SSF55120 85 294 3.36E-51 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MIM_c02950 65005008951f4de3f5ca27faab30fcec 305 Gene3D G3DSA:3.30.2350.10 80 295 1.7E-43 T 12-10-2018 MIM_c02950 65005008951f4de3f5ca27faab30fcec 305 Pfam PF00849 RNA pseudouridylate synthase 98 244 9.8E-22 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MIM_c19580 9d367bc1850e7e2e7f592e2dd624e26b 324 Gene3D G3DSA:3.30.70.1400 22 114 1.7E-23 T 12-10-2018 MIM_c19580 9d367bc1850e7e2e7f592e2dd624e26b 324 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 181 242 2.3E-26 T 12-10-2018 IPR017703 YgfZ/GcvT conserved site MIM_c19580 9d367bc1850e7e2e7f592e2dd624e26b 324 SUPERFAMILY SSF103025 13 236 1.05E-45 T 12-10-2018 MIM_c19580 9d367bc1850e7e2e7f592e2dd624e26b 324 Gene3D G3DSA:2.40.30.160 190 309 5.0E-32 T 12-10-2018 MIM_c02460 db2745dc17f11238f6c503e81db41365 749 Gene3D G3DSA:2.170.130.10 47 205 1.4E-22 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MIM_c02460 db2745dc17f11238f6c503e81db41365 749 SUPERFAMILY SSF56935 61 747 3.0E-116 T 12-10-2018 MIM_c02460 db2745dc17f11238f6c503e81db41365 749 Pfam PF00593 TonB dependent receptor 283 746 3.5E-49 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MIM_c02460 db2745dc17f11238f6c503e81db41365 749 Pfam PF07715 TonB-dependent Receptor Plug Domain 87 197 6.4E-20 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain MIM_c02460 db2745dc17f11238f6c503e81db41365 749 Gene3D G3DSA:2.40.170.20 221 749 6.8E-95 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MIM_c22510 cfe405508c4649257cfed82eb6184a44 232 SUPERFAMILY SSF81338 2 227 1.16E-67 T 12-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 MIM_c22510 cfe405508c4649257cfed82eb6184a44 232 Pfam PF00230 Major intrinsic protein 2 223 6.8E-51 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MIM_c22510 cfe405508c4649257cfed82eb6184a44 232 Gene3D G3DSA:1.20.1080.10 1 229 1.5E-89 T 12-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 MIM_c22510 cfe405508c4649257cfed82eb6184a44 232 TIGRFAM TIGR00861 MIP: MIP family channel proteins 7 223 6.4E-63 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MIM_c22510 cfe405508c4649257cfed82eb6184a44 232 ProSitePatterns PS00221 MIP family signature. 61 69 - T 12-10-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 MIM_c22510 cfe405508c4649257cfed82eb6184a44 232 PRINTS PR00783 Major intrinsic protein family signature 137 155 5.0E-49 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MIM_c22510 cfe405508c4649257cfed82eb6184a44 232 PRINTS PR00783 Major intrinsic protein family signature 206 226 5.0E-49 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MIM_c22510 cfe405508c4649257cfed82eb6184a44 232 PRINTS PR00783 Major intrinsic protein family signature 43 67 5.0E-49 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MIM_c22510 cfe405508c4649257cfed82eb6184a44 232 PRINTS PR00783 Major intrinsic protein family signature 167 189 5.0E-49 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MIM_c22510 cfe405508c4649257cfed82eb6184a44 232 PRINTS PR00783 Major intrinsic protein family signature 3 22 5.0E-49 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MIM_c22510 cfe405508c4649257cfed82eb6184a44 232 PRINTS PR00783 Major intrinsic protein family signature 80 99 5.0E-49 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MIM_c22510 cfe405508c4649257cfed82eb6184a44 232 Hamap MF_01146 Aquaporin Z [aqpZ]. 2 230 35.291 T 12-10-2018 IPR023743 Aquaporin Z GO:0006833|GO:0015250|GO:0016021|GO:0055085 MIM_c06100 3493f483ee1474df0fbabe1dbe75d8d2 194 Pfam PF05845 Bacterial phosphonate metabolism protein (PhnH) 8 191 1.9E-55 T 12-10-2018 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 MIM_c06100 3493f483ee1474df0fbabe1dbe75d8d2 194 Gene3D G3DSA:3.40.50.11310 5 193 2.5E-57 T 12-10-2018 IPR038058 PhnH-like superfamily MIM_c06100 3493f483ee1474df0fbabe1dbe75d8d2 194 SUPERFAMILY SSF159709 16 192 2.48E-50 T 12-10-2018 IPR038058 PhnH-like superfamily MIM_c06100 3493f483ee1474df0fbabe1dbe75d8d2 194 PIRSF PIRSF020680 1 193 4.3E-55 T 12-10-2018 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 MIM_c06100 3493f483ee1474df0fbabe1dbe75d8d2 194 TIGRFAM TIGR03292 PhnH_redo: phosphonate C-P lyase system protein PhnH 10 189 4.1E-50 T 12-10-2018 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 MIM_c27770 384cec9ae913cbafd4f8997671f8f26b 1986 SMART SM01359 1028 1197 8.0E-40 T 12-10-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 MIM_c27770 384cec9ae913cbafd4f8997671f8f26b 1986 Pfam PF11974 Alpha-2-macroglobulin MG1 domain 520 634 1.7E-25 T 12-10-2018 MIM_c27770 384cec9ae913cbafd4f8997671f8f26b 1986 SMART SM01360 1257 1347 4.4E-14 T 12-10-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 MIM_c27770 384cec9ae913cbafd4f8997671f8f26b 1986 Pfam PF00207 Alpha-2-macroglobulin family 1258 1346 2.3E-7 T 12-10-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 MIM_c27770 384cec9ae913cbafd4f8997671f8f26b 1986 SUPERFAMILY SSF48239 1491 1738 2.67E-7 T 12-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid MIM_c27770 384cec9ae913cbafd4f8997671f8f26b 1986 Pfam PF01835 MG2 domain 641 743 1.1E-17 T 12-10-2018 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 MIM_c27770 384cec9ae913cbafd4f8997671f8f26b 1986 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 1028 1197 6.0E-22 T 12-10-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 MIM_c38610 6862e16c2a88c81626eb757ada2b2501 405 Pfam PF07690 Major Facilitator Superfamily 33 331 3.5E-28 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c38610 6862e16c2a88c81626eb757ada2b2501 405 ProSitePatterns PS00216 Sugar transport proteins signature 1. 85 101 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MIM_c38610 6862e16c2a88c81626eb757ada2b2501 405 Gene3D G3DSA:1.20.1250.20 19 402 5.5E-73 T 12-10-2018 MIM_c38610 6862e16c2a88c81626eb757ada2b2501 405 SUPERFAMILY SSF103473 26 401 3.66E-57 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c22290 cf5f040540e328a236d8c946883da786 261 Gene3D G3DSA:3.60.60.10 8 254 4.4E-5 T 12-10-2018 MIM_c22290 cf5f040540e328a236d8c946883da786 261 Pfam PF05742 Transport and Golgi organisation 2 1 239 8.5E-61 T 12-10-2018 IPR008551 Transport and Golgi organisation protein 2 MIM_c32650 64bc14b4c28371cb0c2b67e53d72912d 174 PIRSF PIRSF000194 1 164 1.6E-61 T 12-10-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0046654|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614 MIM_c32650 64bc14b4c28371cb0c2b67e53d72912d 174 PRINTS PR00070 Dihydrofolate reductase signature 30 38 2.8E-15 T 12-10-2018 MIM_c32650 64bc14b4c28371cb0c2b67e53d72912d 174 PRINTS PR00070 Dihydrofolate reductase signature 43 54 2.8E-15 T 12-10-2018 MIM_c32650 64bc14b4c28371cb0c2b67e53d72912d 174 PRINTS PR00070 Dihydrofolate reductase signature 16 26 2.8E-15 T 12-10-2018 MIM_c32650 64bc14b4c28371cb0c2b67e53d72912d 174 PRINTS PR00070 Dihydrofolate reductase signature 95 109 2.8E-15 T 12-10-2018 MIM_c32650 64bc14b4c28371cb0c2b67e53d72912d 174 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 16 38 - T 12-10-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 MIM_c32650 64bc14b4c28371cb0c2b67e53d72912d 174 Pfam PF00186 Dihydrofolate reductase 5 161 8.0E-59 T 12-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 MIM_c32650 64bc14b4c28371cb0c2b67e53d72912d 174 Gene3D G3DSA:3.40.430.10 3 172 2.6E-60 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MIM_c32650 64bc14b4c28371cb0c2b67e53d72912d 174 SUPERFAMILY SSF53597 2 162 2.87E-55 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MIM_24p00010 88e281235aef849511654999bb503df2 286 Pfam PF10134 Replication initiator protein A 22 254 6.2E-85 T 12-10-2018 IPR018777 Replication initiator protein A MIM_c38420 054c0652f4765ec62ba45dfa34fab583 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 318 1.5E-50 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c38420 054c0652f4765ec62ba45dfa34fab583 322 Gene3D G3DSA:3.40.190.150 31 312 2.1E-76 T 12-10-2018 MIM_c38420 054c0652f4765ec62ba45dfa34fab583 322 SUPERFAMILY SSF53850 110 284 2.17E-7 T 12-10-2018 MIM_c38420 054c0652f4765ec62ba45dfa34fab583 322 PIRSF PIRSF017082 1 322 1.4E-50 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c38420 054c0652f4765ec62ba45dfa34fab583 322 Gene3D G3DSA:3.40.190.10 126 247 2.1E-76 T 12-10-2018 MIM_c33870 6a69600972f2b94769297f6d7a8e1b12 685 TIGRFAM TIGR01778 TonB-copper: TonB-dependent copper receptor 52 685 1.2E-271 T 12-10-2018 IPR010100 TonB-dependent copper receptor MIM_c33870 6a69600972f2b94769297f6d7a8e1b12 685 Pfam PF00593 TonB dependent receptor 203 683 2.4E-47 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MIM_c33870 6a69600972f2b94769297f6d7a8e1b12 685 Gene3D G3DSA:2.170.130.10 52 155 2.9E-13 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MIM_c33870 6a69600972f2b94769297f6d7a8e1b12 685 Gene3D G3DSA:2.40.170.20 161 685 3.7E-68 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MIM_c33870 6a69600972f2b94769297f6d7a8e1b12 685 SUPERFAMILY SSF56935 28 685 6.54E-91 T 12-10-2018 MIM_c33870 6a69600972f2b94769297f6d7a8e1b12 685 Pfam PF07715 TonB-dependent Receptor Plug Domain 62 149 3.6E-13 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain MIM_c03200 b3df59c48b76da42e9116feecc72095e 453 Gene3D G3DSA:3.80.30.20 1 363 1.2E-102 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe MIM_c03200 b3df59c48b76da42e9116feecc72095e 453 Pfam PF04055 Radical SAM superfamily 55 226 1.8E-16 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MIM_c03200 b3df59c48b76da42e9116feecc72095e 453 SMART SM00729 50 272 8.9E-43 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MIM_c03200 b3df59c48b76da42e9116feecc72095e 453 SUPERFAMILY SSF102114 3 437 1.44E-115 T 12-10-2018 MIM_c03200 b3df59c48b76da42e9116feecc72095e 453 Gene3D G3DSA:1.10.10.920 364 453 1.4E-15 T 12-10-2018 MIM_c03200 b3df59c48b76da42e9116feecc72095e 453 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 3 452 8.8E-129 T 12-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 MIM_c03200 b3df59c48b76da42e9116feecc72095e 453 PIRSF PIRSF000167 1 449 8.0E-142 T 12-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 MIM_c05040 a3a5b50a65718a15842d640773043f46 186 SUPERFAMILY SSF89028 7 179 1.94E-55 T 12-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 MIM_c05040 a3a5b50a65718a15842d640773043f46 186 Gene3D G3DSA:1.20.1200.10 17 184 3.4E-59 T 12-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 MIM_c05040 a3a5b50a65718a15842d640773043f46 186 Pfam PF01923 Cobalamin adenosyltransferase 8 166 6.3E-55 T 12-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 MIM_c05040 a3a5b50a65718a15842d640773043f46 186 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 24 179 1.0E-45 T 12-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 MIM_c05040 a3a5b50a65718a15842d640773043f46 186 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 10 179 1.3E-55 T 12-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 MIM_c07290 7363e2d520db1a1aaa60a399aa96340b 251 SMART SM00382 30 222 4.7E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c07290 7363e2d520db1a1aaa60a399aa96340b 251 Pfam PF00005 ABC transporter 21 174 1.0E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c07290 7363e2d520db1a1aaa60a399aa96340b 251 Gene3D G3DSA:3.40.50.300 1 251 3.1E-77 T 12-10-2018 MIM_c07290 7363e2d520db1a1aaa60a399aa96340b 251 PIRSF PIRSF039085 2 250 5.8E-113 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MIM_c07290 7363e2d520db1a1aaa60a399aa96340b 251 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c07290 7363e2d520db1a1aaa60a399aa96340b 251 SUPERFAMILY SSF52540 5 244 2.84E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c16710 05d2dfbb9ae11c170912f24317ee67af 218 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 196 7.8E-81 T 12-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 MIM_c16710 05d2dfbb9ae11c170912f24317ee67af 218 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 210 42.178 T 12-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 MIM_c16710 05d2dfbb9ae11c170912f24317ee67af 218 SUPERFAMILY SSF52016 1 200 9.61E-60 T 12-10-2018 MIM_c16710 05d2dfbb9ae11c170912f24317ee67af 218 Pfam PF00694 Aconitase C-terminal domain 1 131 1.2E-36 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 MIM_c16710 05d2dfbb9ae11c170912f24317ee67af 218 Gene3D G3DSA:3.20.19.10 1 188 6.9E-75 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 MIM_c16780 053779f439b1c464f5e2ed501577f88f 222 SUPERFAMILY SSF51366 3 210 1.27E-50 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MIM_c16780 053779f439b1c464f5e2ed501577f88f 222 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 5 207 2.9E-37 T 12-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 MIM_c16780 053779f439b1c464f5e2ed501577f88f 222 Gene3D G3DSA:3.20.20.70 2 211 1.8E-56 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c16780 053779f439b1c464f5e2ed501577f88f 222 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 3 213 36.296 T 12-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 MIM_c12420 fd8df3121e3926e142715ca0bd200d18 264 Gene3D G3DSA:3.40.190.80 147 264 1.3E-30 T 12-10-2018 MIM_c12420 fd8df3121e3926e142715ca0bd200d18 264 SUPERFAMILY SSF56655 1 259 2.23E-80 T 12-10-2018 MIM_c12420 fd8df3121e3926e142715ca0bd200d18 264 Pfam PF00459 Inositol monophosphatase family 2 261 1.3E-62 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MIM_c12420 fd8df3121e3926e142715ca0bd200d18 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 136 159 5.0E-57 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MIM_c12420 fd8df3121e3926e142715ca0bd200d18 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 213 237 5.0E-57 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MIM_c12420 fd8df3121e3926e142715ca0bd200d18 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 5.0E-57 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MIM_c12420 fd8df3121e3926e142715ca0bd200d18 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 87 103 5.0E-57 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MIM_c12420 fd8df3121e3926e142715ca0bd200d18 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 5.0E-57 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MIM_c12420 fd8df3121e3926e142715ca0bd200d18 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 182 203 5.0E-57 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MIM_c12420 fd8df3121e3926e142715ca0bd200d18 264 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 216 230 - T 12-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 MIM_c12420 fd8df3121e3926e142715ca0bd200d18 264 PRINTS PR01959 SuhB family inositol monophosphatase signature 110 129 4.4E-17 T 12-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 MIM_c12420 fd8df3121e3926e142715ca0bd200d18 264 PRINTS PR01959 SuhB family inositol monophosphatase signature 203 215 4.4E-17 T 12-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 MIM_c12420 fd8df3121e3926e142715ca0bd200d18 264 PRINTS PR01959 SuhB family inositol monophosphatase signature 17 39 4.4E-17 T 12-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 MIM_c12420 fd8df3121e3926e142715ca0bd200d18 264 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 87 100 - T 12-10-2018 IPR020583 Inositol monophosphatase, metal-binding site MIM_c12420 fd8df3121e3926e142715ca0bd200d18 264 Gene3D G3DSA:3.30.540.10 1 146 3.8E-52 T 12-10-2018 MIM_c27110 f1b3fab446e5dc009ff351d5fc4c4ba9 239 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 26 119 2.4E-25 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c27110 f1b3fab446e5dc009ff351d5fc4c4ba9 239 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 225 8.6E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c27110 f1b3fab446e5dc009ff351d5fc4c4ba9 239 Gene3D G3DSA:1.10.3720.10 18 229 1.6E-51 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c27110 f1b3fab446e5dc009ff351d5fc4c4ba9 239 SUPERFAMILY SSF161098 24 211 7.33E-42 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c00220 33aade0d1d8538ad3e4fecab9005b789 167 SUPERFAMILY SSF55729 3 164 5.13E-34 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c00220 33aade0d1d8538ad3e4fecab9005b789 167 Gene3D G3DSA:3.40.630.30 1 167 2.7E-33 T 12-10-2018 MIM_c00220 33aade0d1d8538ad3e4fecab9005b789 167 Pfam PF13302 Acetyltransferase (GNAT) domain 13 140 6.2E-16 T 12-10-2018 IPR000182 GNAT domain MIM_c33510 f8178f60a3c5138bef9308f8dd2a3279 243 SMART SM01236 78 181 6.5E-27 T 12-10-2018 MIM_c33510 f8178f60a3c5138bef9308f8dd2a3279 243 Pfam PF14518 Iron-containing redox enzyme 44 215 1.5E-36 T 12-10-2018 MIM_c33510 f8178f60a3c5138bef9308f8dd2a3279 243 Gene3D G3DSA:1.20.910.10 1 239 1.4E-58 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 MIM_c33510 f8178f60a3c5138bef9308f8dd2a3279 243 SUPERFAMILY SSF48613 9 226 1.28E-50 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 MIM_c00570 675a7c3c3a740067b850a911aa8c2d54 305 Gene3D G3DSA:1.10.3720.10 60 300 1.8E-57 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c00570 675a7c3c3a740067b850a911aa8c2d54 305 SUPERFAMILY SSF161098 64 290 1.18E-51 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c00570 675a7c3c3a740067b850a911aa8c2d54 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 292 5.0E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c39170 5fcb96ece22a1be5ca9b15dbc58d632c 513 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 21 445 4.0E-141 T 12-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane MIM_c32820 0249ea05761364c3d33b67c521f5e8f7 812 Gene3D G3DSA:3.30.70.100 698 790 9.3E-9 T 12-10-2018 MIM_c32820 0249ea05761364c3d33b67c521f5e8f7 812 Gene3D G3DSA:2.30.30.60 645 693 1.2E-10 T 12-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily MIM_c32820 0249ea05761364c3d33b67c521f5e8f7 812 SUPERFAMILY SSF82689 699 791 1.57E-12 T 12-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MIM_c32820 0249ea05761364c3d33b67c521f5e8f7 812 SUPERFAMILY SSF82861 545 628 4.58E-11 T 12-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 MIM_c32820 0249ea05761364c3d33b67c521f5e8f7 812 Pfam PF12607 Protein of unknown function (DUF3772) 144 205 1.7E-18 T 12-10-2018 IPR022249 Domain of unknown function DUF3772 MIM_c32820 0249ea05761364c3d33b67c521f5e8f7 812 SUPERFAMILY SSF50182 630 695 8.17E-16 T 12-10-2018 IPR010920 LSM domain superfamily MIM_c32820 0249ea05761364c3d33b67c521f5e8f7 812 Pfam PF00924 Mechanosensitive ion channel 590 785 7.5E-41 T 12-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MIM_c32080 a476c671d8adccca1997fab13385e921 170 SUPERFAMILY SSF142433 6 167 2.09E-53 T 12-10-2018 IPR036653 CinA-like, C-terminal MIM_c32080 a476c671d8adccca1997fab13385e921 170 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 15 164 1.6E-45 T 12-10-2018 IPR008136 CinA, C-terminal MIM_c32080 a476c671d8adccca1997fab13385e921 170 Gene3D G3DSA:3.90.950.20 3 167 1.2E-56 T 12-10-2018 IPR036653 CinA-like, C-terminal MIM_c32080 a476c671d8adccca1997fab13385e921 170 Pfam PF02464 Competence-damaged protein 10 165 1.8E-53 T 12-10-2018 IPR008136 CinA, C-terminal MIM_c02400 bb2429613b9eefe76e4f54cb3e592811 340 Gene3D G3DSA:1.10.4100.10 1 311 3.2E-25 T 12-10-2018 MIM_c02400 bb2429613b9eefe76e4f54cb3e592811 340 SUPERFAMILY SSF103378 2 245 2.48E-7 T 12-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 MIM_c02400 bb2429613b9eefe76e4f54cb3e592811 340 Pfam PF03972 MmgE/PrpD family 6 245 3.3E-8 T 12-10-2018 IPR005656 MmgE/PrpD GO:0016829 MIM_c28720 990f1eb41b42635a53d8bca2f464cbf7 117 SUPERFAMILY SSF54909 1 115 2.2E-51 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel MIM_c28720 990f1eb41b42635a53d8bca2f464cbf7 117 Pfam PF07237 Protein of unknown function (DUF1428) 2 103 3.7E-46 T 12-10-2018 IPR009874 Protein of unknown function DUF1428 MIM_c28720 990f1eb41b42635a53d8bca2f464cbf7 117 Gene3D G3DSA:3.30.70.100 1 116 4.9E-46 T 12-10-2018 MIM_c28720 990f1eb41b42635a53d8bca2f464cbf7 117 PIRSF PIRSF007028 1 117 2.3E-50 T 12-10-2018 IPR009874 Protein of unknown function DUF1428 MIM_c19040 4f842dbff1c23a7efe5f27d772ae36ae 360 Gene3D G3DSA:3.40.50.300 1 239 5.4E-75 T 12-10-2018 MIM_c19040 4f842dbff1c23a7efe5f27d772ae36ae 360 SUPERFAMILY SSF52540 4 244 1.21E-86 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c19040 4f842dbff1c23a7efe5f27d772ae36ae 360 Gene3D G3DSA:2.40.50.100 240 352 2.7E-16 T 12-10-2018 MIM_c19040 4f842dbff1c23a7efe5f27d772ae36ae 360 Gene3D G3DSA:2.40.50.140 293 342 2.7E-16 T 12-10-2018 MIM_c19040 4f842dbff1c23a7efe5f27d772ae36ae 360 SMART SM00382 29 212 1.9E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c19040 4f842dbff1c23a7efe5f27d772ae36ae 360 Pfam PF00005 ABC transporter 21 162 8.1E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c19040 4f842dbff1c23a7efe5f27d772ae36ae 360 SUPERFAMILY SSF50331 237 359 4.13E-22 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MIM_c19040 4f842dbff1c23a7efe5f27d772ae36ae 360 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c19040 4f842dbff1c23a7efe5f27d772ae36ae 360 Pfam PF08402 TOBE domain 279 347 8.5E-5 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 MIM_c37210 20f149a5bdd7c7cce1963e457e2f814f 241 SUPERFAMILY SSF51735 9 240 5.13E-73 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c37210 20f149a5bdd7c7cce1963e457e2f814f 241 Gene3D G3DSA:3.40.50.720 1 240 6.1E-76 T 12-10-2018 MIM_c37210 20f149a5bdd7c7cce1963e457e2f814f 241 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c37210 20f149a5bdd7c7cce1963e457e2f814f 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 2.6E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c37210 20f149a5bdd7c7cce1963e457e2f814f 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 2.6E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c37210 20f149a5bdd7c7cce1963e457e2f814f 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 2.6E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c37210 20f149a5bdd7c7cce1963e457e2f814f 241 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 238 3.2E-56 T 12-10-2018 MIM_c37210 20f149a5bdd7c7cce1963e457e2f814f 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.3E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c37210 20f149a5bdd7c7cce1963e457e2f814f 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 1.3E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c37210 20f149a5bdd7c7cce1963e457e2f814f 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 1.3E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c37210 20f149a5bdd7c7cce1963e457e2f814f 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 1.3E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c37210 20f149a5bdd7c7cce1963e457e2f814f 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 1.3E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c37210 20f149a5bdd7c7cce1963e457e2f814f 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 222 1.3E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c00640 b8dfdb6fd277c3af15362fe6f86b2223 304 SMART SM00850 204 303 1.2E-14 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 MIM_c00640 b8dfdb6fd277c3af15362fe6f86b2223 304 Gene3D G3DSA:3.30.450.40 33 190 4.6E-15 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c00640 b8dfdb6fd277c3af15362fe6f86b2223 304 Pfam PF04397 LytTr DNA-binding domain 209 302 1.7E-13 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 MIM_c00640 b8dfdb6fd277c3af15362fe6f86b2223 304 Pfam PF01590 GAF domain 39 177 4.2E-7 T 12-10-2018 IPR003018 GAF domain GO:0005515 MIM_c00640 b8dfdb6fd277c3af15362fe6f86b2223 304 SMART SM00065 34 188 7.8E-8 T 12-10-2018 IPR003018 GAF domain GO:0005515 MIM_c00640 b8dfdb6fd277c3af15362fe6f86b2223 304 SUPERFAMILY SSF55781 37 177 3.68E-15 T 12-10-2018 MIM_c17430 2e9dbcea2b129190eb31d73fd9e77663 222 SUPERFAMILY SSF161098 19 213 4.19E-41 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c17430 2e9dbcea2b129190eb31d73fd9e77663 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 18 116 1.1E-24 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c17430 2e9dbcea2b129190eb31d73fd9e77663 222 Gene3D G3DSA:1.10.3720.10 9 221 2.3E-47 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c17430 2e9dbcea2b129190eb31d73fd9e77663 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 215 2.1E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c18200 8661a988d12db6358a9e3fd4dfceeffd 169 Gene3D G3DSA:2.60.120.380 59 168 2.0E-8 T 12-10-2018 MIM_c40250 9dd25457546690d98f44db47df42e4fb 186 Pfam PF03352 Methyladenine glycosylase 16 125 1.4E-38 T 12-10-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 MIM_c40250 9dd25457546690d98f44db47df42e4fb 186 SUPERFAMILY SSF48150 15 171 5.49E-48 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MIM_c40250 9dd25457546690d98f44db47df42e4fb 186 Gene3D G3DSA:1.10.340.30 10 172 4.7E-43 T 12-10-2018 MIM_c26270 d8b8d2ff6589ee7dcd6859721e061527 305 Pfam PF00589 Phage integrase family 119 290 5.8E-50 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MIM_c26270 d8b8d2ff6589ee7dcd6859721e061527 305 Gene3D G3DSA:1.10.443.10 117 299 1.7E-66 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MIM_c26270 d8b8d2ff6589ee7dcd6859721e061527 305 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 12 305 55.24 T 12-10-2018 IPR023009 Tyrosine recombinase XerC/XerD MIM_c26270 d8b8d2ff6589ee7dcd6859721e061527 305 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 17 305 7.7E-114 T 12-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 MIM_c26270 d8b8d2ff6589ee7dcd6859721e061527 305 Gene3D G3DSA:1.10.150.130 10 105 1.1E-19 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal MIM_c26270 d8b8d2ff6589ee7dcd6859721e061527 305 SUPERFAMILY SSF47823 10 107 5.1E-27 T 12-10-2018 MIM_c26270 d8b8d2ff6589ee7dcd6859721e061527 305 SUPERFAMILY SSF56349 113 303 1.71E-55 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MIM_c26270 d8b8d2ff6589ee7dcd6859721e061527 305 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 10 305 58.182 T 12-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 MIM_c26270 d8b8d2ff6589ee7dcd6859721e061527 305 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 14 96 2.0E-18 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MIM_c15730 8ed812af6f3c9ade6957685301ead0e9 626 Pfam PF02705 K+ potassium transporter 15 544 2.7E-202 T 12-10-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 MIM_c15730 8ed812af6f3c9ade6957685301ead0e9 626 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 6 626 32.697 T 12-10-2018 IPR023051 Potassium uptake protein, low affinity, Kup MIM_c18160 22059accaad149a914be281baf99f464 398 TIGRFAM TIGR00843 benE: benzoate transporter 13 388 1.2E-119 T 12-10-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 MIM_c18160 22059accaad149a914be281baf99f464 398 Pfam PF03594 Benzoate membrane transport protein 10 386 1.5E-135 T 12-10-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 MIM_c12970 fcceb9753799b3276bcc0dc7658771a9 386 Gene3D G3DSA:3.40.640.10 45 281 6.7E-112 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c12970 fcceb9753799b3276bcc0dc7658771a9 386 Pfam PF00155 Aminotransferase class I and II 30 375 2.7E-55 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MIM_c12970 fcceb9753799b3276bcc0dc7658771a9 386 SUPERFAMILY SSF53383 24 378 1.9E-95 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c12970 fcceb9753799b3276bcc0dc7658771a9 386 Gene3D G3DSA:3.90.1150.10 30 372 6.7E-112 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c12970 fcceb9753799b3276bcc0dc7658771a9 386 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 230 239 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 MIM_c00310 5c9a1755268b6cb973fcc219e10174c0 276 Pfam PF04909 Amidohydrolase 10 274 1.4E-31 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MIM_c00310 5c9a1755268b6cb973fcc219e10174c0 276 Gene3D G3DSA:3.20.20.140 2 276 1.2E-67 T 12-10-2018 MIM_c00310 5c9a1755268b6cb973fcc219e10174c0 276 SUPERFAMILY SSF51556 5 274 1.42E-61 T 12-10-2018 IPR032466 Metal-dependent hydrolase MIM_c11410 ddab59785d35c3888e59150b895819b8 452 ProSitePatterns PS00216 Sugar transport proteins signature 1. 319 336 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MIM_c11410 ddab59785d35c3888e59150b895819b8 452 Pfam PF07690 Major Facilitator Superfamily 53 408 5.8E-15 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c11410 ddab59785d35c3888e59150b895819b8 452 SUPERFAMILY SSF103473 38 448 1.24E-39 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c11410 ddab59785d35c3888e59150b895819b8 452 Gene3D G3DSA:1.20.1250.20 37 451 2.6E-39 T 12-10-2018 MIM_c38900 260cb6808924941dbd40fb38abbfd8a9 107 SUPERFAMILY SSF54913 2 105 2.93E-33 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta MIM_c38900 260cb6808924941dbd40fb38abbfd8a9 107 Gene3D G3DSA:3.30.70.120 1 107 1.1E-33 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MIM_c38900 260cb6808924941dbd40fb38abbfd8a9 107 Pfam PF03091 CutA1 divalent ion tolerance protein 6 103 3.0E-30 T 12-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 MIM_c39060 e0793fa5163618dbce9b105d333dd344 101 Pfam PF00253 Ribosomal protein S14p/S29e 47 100 3.6E-27 T 12-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c39060 e0793fa5163618dbce9b105d333dd344 101 SUPERFAMILY SSF57716 2 101 5.2E-39 T 12-10-2018 MIM_c39060 e0793fa5163618dbce9b105d333dd344 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 27.188 T 12-10-2018 IPR023036 Ribosomal protein S14, bacterial/plastid MIM_c39060 e0793fa5163618dbce9b105d333dd344 101 Gene3D G3DSA:4.10.830.10 40 101 6.3E-24 T 12-10-2018 MIM_c11250 2f5acd344909bffec77c4604ed3fff21 272 Pfam PF00149 Calcineurin-like phosphoesterase 1 195 2.0E-15 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MIM_c11250 2f5acd344909bffec77c4604ed3fff21 272 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 1 253 32.208 T 12-10-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 MIM_c11250 2f5acd344909bffec77c4604ed3fff21 272 Gene3D G3DSA:3.60.21.10 1 270 5.1E-69 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like MIM_c11250 2f5acd344909bffec77c4604ed3fff21 272 SUPERFAMILY SSF56300 1 250 3.04E-46 T 12-10-2018 MIM_c19790 319078fbafa73e0220c0e9181ae5842a 222 Gene3D G3DSA:3.50.30.100 2 201 3.5E-58 T 12-10-2018 MIM_c19790 319078fbafa73e0220c0e9181ae5842a 222 Pfam PF03737 Aldolase/RraA 17 179 9.3E-32 T 12-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MIM_c19790 319078fbafa73e0220c0e9181ae5842a 222 SUPERFAMILY SSF89562 14 190 5.76E-34 T 12-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily MIM_c27080 b9915321da5996c2e5f9a0a633847c33 266 Pfam PF12697 Alpha/beta hydrolase family 33 256 1.4E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c27080 b9915321da5996c2e5f9a0a633847c33 266 SUPERFAMILY SSF53474 17 263 5.49E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c27080 b9915321da5996c2e5f9a0a633847c33 266 Gene3D G3DSA:3.40.50.1820 9 264 7.3E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c17290 b6cddb88fb8b2d1dfa8a794c93d0b4cf 225 Pfam PF12973 ChrR Cupin-like domain 19 108 5.6E-41 T 12-10-2018 IPR025979 ChrR-like cupin domain MIM_c17290 b6cddb88fb8b2d1dfa8a794c93d0b4cf 225 Pfam PF12973 ChrR Cupin-like domain 139 212 4.7E-8 T 12-10-2018 IPR025979 ChrR-like cupin domain MIM_c17290 b6cddb88fb8b2d1dfa8a794c93d0b4cf 225 Gene3D G3DSA:2.60.120.10 2 220 5.2E-83 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c17290 b6cddb88fb8b2d1dfa8a794c93d0b4cf 225 SUPERFAMILY SSF51182 3 126 3.71E-33 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c17290 b6cddb88fb8b2d1dfa8a794c93d0b4cf 225 SUPERFAMILY SSF51182 137 216 5.26E-12 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c04460 36ec9cdf8312a0ebec03d2406f02ab18 153 Gene3D G3DSA:3.30.70.920 57 140 8.6E-16 T 12-10-2018 MIM_c04460 36ec9cdf8312a0ebec03d2406f02ab18 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 7.5E-10 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MIM_c04460 36ec9cdf8312a0ebec03d2406f02ab18 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 7.5E-10 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MIM_c04460 36ec9cdf8312a0ebec03d2406f02ab18 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 7.5E-10 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MIM_c04460 36ec9cdf8312a0ebec03d2406f02ab18 153 SMART SM00344 3 112 2.1E-31 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MIM_c04460 36ec9cdf8312a0ebec03d2406f02ab18 153 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 50 3.4E-16 T 12-10-2018 MIM_c04460 36ec9cdf8312a0ebec03d2406f02ab18 153 Pfam PF01037 Lrp/AsnC ligand binding domain 69 141 4.8E-13 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MIM_c04460 36ec9cdf8312a0ebec03d2406f02ab18 153 Gene3D G3DSA:1.10.10.10 1 56 5.9E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c04460 36ec9cdf8312a0ebec03d2406f02ab18 153 SUPERFAMILY SSF54909 64 149 9.92E-12 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel MIM_c04460 36ec9cdf8312a0ebec03d2406f02ab18 153 SUPERFAMILY SSF46785 2 88 4.43E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c33580 c805bc016dc9808b9927cf7dd89fbfaf 378 Gene3D G3DSA:1.10.287.470 126 193 3.5E-9 T 12-10-2018 MIM_c33580 c805bc016dc9808b9927cf7dd89fbfaf 378 SUPERFAMILY SSF111369 197 295 7.32E-13 T 12-10-2018 MIM_c33580 c805bc016dc9808b9927cf7dd89fbfaf 378 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 57 303 2.9E-17 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MIM_c33580 c805bc016dc9808b9927cf7dd89fbfaf 378 Pfam PF00529 HlyD membrane-fusion protein of T1SS 304 353 6.6E-9 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MIM_c33580 c805bc016dc9808b9927cf7dd89fbfaf 378 Gene3D G3DSA:1.10.287.470 92 123 3.5E-11 T 12-10-2018 MIM_c33580 c805bc016dc9808b9927cf7dd89fbfaf 378 SUPERFAMILY SSF111369 61 141 9.42E-7 T 12-10-2018 MIM_c33580 c805bc016dc9808b9927cf7dd89fbfaf 378 Gene3D G3DSA:2.40.30.170 242 359 6.5E-37 T 12-10-2018 MIM_c33580 c805bc016dc9808b9927cf7dd89fbfaf 378 Gene3D G3DSA:2.40.50.100 58 91 3.5E-11 T 12-10-2018 MIM_c24550 9ac79ea40dcd8e3fa1217ba6df46eb44 164 PIRSF PIRSF000216 3 164 1.7E-55 T 12-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24550 9ac79ea40dcd8e3fa1217ba6df46eb44 164 Gene3D G3DSA:1.10.10.1590 1 74 3.6E-24 T 12-10-2018 MIM_c24550 9ac79ea40dcd8e3fa1217ba6df46eb44 164 SUPERFAMILY SSF52833 4 159 2.35E-49 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c24550 9ac79ea40dcd8e3fa1217ba6df46eb44 164 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 12 157 2.2E-49 T 12-10-2018 MIM_c24550 9ac79ea40dcd8e3fa1217ba6df46eb44 164 Gene3D G3DSA:3.40.30.10 75 164 1.6E-24 T 12-10-2018 MIM_c24550 9ac79ea40dcd8e3fa1217ba6df46eb44 164 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 11 157 1.1E-58 T 12-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c13040 4386b36517c16cd484750ef61c8f600f 388 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 339 358 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MIM_c13040 4386b36517c16cd484750ef61c8f600f 388 Gene3D G3DSA:2.40.110.10 124 237 1.2E-39 T 12-10-2018 MIM_c13040 4386b36517c16cd484750ef61c8f600f 388 PIRSF PIRSF016578 3 113 6.8E-9 T 12-10-2018 MIM_c13040 4386b36517c16cd484750ef61c8f600f 388 PIRSF PIRSF016578 133 211 0.0075 T 12-10-2018 MIM_c13040 4386b36517c16cd484750ef61c8f600f 388 PIRSF PIRSF016578 242 384 9.8E-12 T 12-10-2018 MIM_c13040 4386b36517c16cd484750ef61c8f600f 388 Gene3D G3DSA:1.10.540.10 1 123 3.4E-43 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c13040 4386b36517c16cd484750ef61c8f600f 388 SUPERFAMILY SSF56645 4 245 2.36E-79 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c13040 4386b36517c16cd484750ef61c8f600f 388 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 380 2.9E-53 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MIM_c13040 4386b36517c16cd484750ef61c8f600f 388 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 120 1.1E-35 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c13040 4386b36517c16cd484750ef61c8f600f 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 220 8.3E-29 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MIM_c13040 4386b36517c16cd484750ef61c8f600f 388 Gene3D G3DSA:1.20.140.10 238 386 6.4E-58 T 12-10-2018 MIM_c13040 4386b36517c16cd484750ef61c8f600f 388 SUPERFAMILY SSF47203 230 382 1.16E-59 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c36220 1a3db45f060723043ec6c06e5fdc43ce 146 ProSitePatterns PS00018 EF-hand calcium-binding domain. 65 77 - T 12-10-2018 IPR018247 EF-Hand 1, calcium-binding site MIM_c36220 1a3db45f060723043ec6c06e5fdc43ce 146 Pfam PF13202 EF hand 110 127 1.6E-4 T 12-10-2018 IPR002048 EF-hand domain GO:0005509 MIM_c36220 1a3db45f060723043ec6c06e5fdc43ce 146 Pfam PF13202 EF hand 84 103 0.12 T 12-10-2018 IPR002048 EF-hand domain GO:0005509 MIM_c36220 1a3db45f060723043ec6c06e5fdc43ce 146 Pfam PF13202 EF hand 61 79 0.0046 T 12-10-2018 IPR002048 EF-hand domain GO:0005509 MIM_c36220 1a3db45f060723043ec6c06e5fdc43ce 146 ProSitePatterns PS00018 EF-hand calcium-binding domain. 114 126 - T 12-10-2018 IPR018247 EF-Hand 1, calcium-binding site MIM_c36220 1a3db45f060723043ec6c06e5fdc43ce 146 SUPERFAMILY SSF47473 59 144 4.01E-15 T 12-10-2018 IPR011992 EF-hand domain pair MIM_c36220 1a3db45f060723043ec6c06e5fdc43ce 146 Gene3D G3DSA:1.10.238.10 108 146 6.9E-6 T 12-10-2018 MIM_c36220 1a3db45f060723043ec6c06e5fdc43ce 146 Gene3D G3DSA:1.10.238.10 55 106 2.6E-8 T 12-10-2018 MIM_c01650 8a8df005646be0fd07d1fa6b05d39047 174 SUPERFAMILY SSF81342 8 174 8.63E-25 T 12-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 MIM_c01650 8a8df005646be0fd07d1fa6b05d39047 174 Pfam PF01292 Prokaryotic cytochrome b561 9 173 3.3E-18 T 12-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 MIM_c20500 fb923c0cba17c4b93a848ec7272fa297 495 Pfam PF00171 Aldehyde dehydrogenase family 26 490 7.6E-165 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c20500 fb923c0cba17c4b93a848ec7272fa297 495 SUPERFAMILY SSF53720 9 493 1.7E-162 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c20500 fb923c0cba17c4b93a848ec7272fa297 495 Gene3D G3DSA:3.40.309.10 268 460 9.3E-174 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MIM_c20500 fb923c0cba17c4b93a848ec7272fa297 495 Gene3D G3DSA:3.40.605.10 22 487 9.3E-174 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c20500 fb923c0cba17c4b93a848ec7272fa297 495 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 263 270 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MIM_c20500 fb923c0cba17c4b93a848ec7272fa297 495 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 291 302 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MIM_c40280 7b918be9c7efc9b3ba40cebcecb57cbf 256 Gene3D G3DSA:3.40.50.720 1 254 6.6E-79 T 12-10-2018 MIM_c40280 7b918be9c7efc9b3ba40cebcecb57cbf 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c40280 7b918be9c7efc9b3ba40cebcecb57cbf 256 SUPERFAMILY SSF51735 4 250 1.17E-74 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c40280 7b918be9c7efc9b3ba40cebcecb57cbf 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 1.6E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c40280 7b918be9c7efc9b3ba40cebcecb57cbf 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 1.6E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c40280 7b918be9c7efc9b3ba40cebcecb57cbf 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 1.6E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c40280 7b918be9c7efc9b3ba40cebcecb57cbf 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 250 9.6E-59 T 12-10-2018 MIM_c40280 7b918be9c7efc9b3ba40cebcecb57cbf 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 187 0.0072 T 12-10-2018 MIM_c40280 7b918be9c7efc9b3ba40cebcecb57cbf 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.2E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c40280 7b918be9c7efc9b3ba40cebcecb57cbf 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 4.2E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c40280 7b918be9c7efc9b3ba40cebcecb57cbf 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 4.2E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c40280 7b918be9c7efc9b3ba40cebcecb57cbf 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 4.2E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c40280 7b918be9c7efc9b3ba40cebcecb57cbf 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 4.2E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c40280 7b918be9c7efc9b3ba40cebcecb57cbf 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 4.2E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c36930 16ad5303c9450a2374ff6cba0ba75f45 212 PRINTS PR01021 OMPA domain signature 108 130 1.0E-11 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MIM_c36930 16ad5303c9450a2374ff6cba0ba75f45 212 PRINTS PR01021 OMPA domain signature 153 169 1.0E-11 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MIM_c36930 16ad5303c9450a2374ff6cba0ba75f45 212 PRINTS PR01021 OMPA domain signature 138 153 1.0E-11 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MIM_c36930 16ad5303c9450a2374ff6cba0ba75f45 212 Gene3D G3DSA:3.30.1330.60 78 211 1.4E-39 T 12-10-2018 IPR036737 OmpA-like domain superfamily MIM_c36930 16ad5303c9450a2374ff6cba0ba75f45 212 Pfam PF00691 OmpA family 107 202 7.1E-20 T 12-10-2018 IPR006665 OmpA-like domain MIM_c36930 16ad5303c9450a2374ff6cba0ba75f45 212 SUPERFAMILY SSF103088 96 208 8.76E-35 T 12-10-2018 IPR036737 OmpA-like domain superfamily MIM_c36930 16ad5303c9450a2374ff6cba0ba75f45 212 Pfam PF13441 YMGG-like Gly-zipper 26 69 3.2E-7 T 12-10-2018 IPR027367 YMGG-like Gly-zipper MIM_c13660 116ff3db4ca471eb3db1027047f6b3e2 329 SUPERFAMILY SSF51430 1 313 1.83E-102 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MIM_c13660 116ff3db4ca471eb3db1027047f6b3e2 329 Gene3D G3DSA:3.20.20.100 1 328 1.9E-117 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MIM_c13660 116ff3db4ca471eb3db1027047f6b3e2 329 Pfam PF00248 Aldo/keto reductase family 16 308 1.1E-72 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 Gene3D G3DSA:3.30.70.1440 668 864 0.0 T 12-10-2018 MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 SUPERFAMILY SSF82693 135 329 1.02E-20 T 12-10-2018 MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 Gene3D G3DSA:3.30.70.1430 38 816 0.0 T 12-10-2018 MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 SUPERFAMILY SSF82693 671 855 8.89E-21 T 12-10-2018 MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 SUPERFAMILY SSF82714 721 806 1.14E-17 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 Gene3D G3DSA:3.30.2090.10 179 275 0.0 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 SUPERFAMILY SSF82866 834 1023 8.11E-41 T 12-10-2018 MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 Pfam PF00873 AcrB/AcrD/AcrF family 1 1024 0.0 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 SUPERFAMILY SSF82866 297 497 9.55E-48 T 12-10-2018 MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 Gene3D G3DSA:3.30.70.1430 567 667 0.0 T 12-10-2018 MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 PRINTS PR00702 Acriflavin resistance protein family signature 552 569 2.3E-95 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 2.3E-95 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 2.3E-95 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 PRINTS PR00702 Acriflavin resistance protein family signature 619 633 2.3E-95 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 2.3E-95 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 2.3E-95 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 2.3E-95 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 2.3E-95 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 2.3E-95 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 SUPERFAMILY SSF82693 38 129 2.96E-25 T 12-10-2018 MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 Gene3D G3DSA:1.20.1640.10 513 1021 0.0 T 12-10-2018 MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 SUPERFAMILY SSF82693 565 669 8.89E-26 T 12-10-2018 MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1033 0.0 T 12-10-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0006855|GO:0015562|GO:0016021 MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 SUPERFAMILY SSF82714 182 272 7.46E-22 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 Gene3D G3DSA:1.20.1640.10 8 512 0.0 T 12-10-2018 MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 Gene3D G3DSA:3.30.2090.10 720 808 0.0 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MIM_c21240 a4fe9ae64e0c26ee009035fe753c440d 1083 Gene3D G3DSA:3.30.70.1320 133 332 0.0 T 12-10-2018 MIM_c37220 56036844ac02b9625b425d12d66d9365 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c37220 56036844ac02b9625b425d12d66d9365 248 Gene3D G3DSA:3.40.50.720 2 247 6.0E-74 T 12-10-2018 MIM_c37220 56036844ac02b9625b425d12d66d9365 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 5.3E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c37220 56036844ac02b9625b425d12d66d9365 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 5.3E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c37220 56036844ac02b9625b425d12d66d9365 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 5.3E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c37220 56036844ac02b9625b425d12d66d9365 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 3.9E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c37220 56036844ac02b9625b425d12d66d9365 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 3.9E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c37220 56036844ac02b9625b425d12d66d9365 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 3.9E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c37220 56036844ac02b9625b425d12d66d9365 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 3.9E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c37220 56036844ac02b9625b425d12d66d9365 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 3.9E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c37220 56036844ac02b9625b425d12d66d9365 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 3.9E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c37220 56036844ac02b9625b425d12d66d9365 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 244 3.0E-57 T 12-10-2018 MIM_c37220 56036844ac02b9625b425d12d66d9365 248 SUPERFAMILY SSF51735 8 245 1.58E-70 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c12110 964b7374a427af45fba6813658bb9484 244 PIRSF PIRSF039085 1 243 4.1E-101 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MIM_c12110 964b7374a427af45fba6813658bb9484 244 Pfam PF00005 ABC transporter 18 165 5.5E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c12110 964b7374a427af45fba6813658bb9484 244 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c12110 964b7374a427af45fba6813658bb9484 244 SUPERFAMILY SSF52540 1 228 1.5E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c12110 964b7374a427af45fba6813658bb9484 244 Gene3D G3DSA:3.40.50.300 1 239 4.9E-75 T 12-10-2018 MIM_c12110 964b7374a427af45fba6813658bb9484 244 SMART SM00382 26 213 1.8E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c39660 a8c5d9a68c7d1a5650bbcb29a60b9cfc 109 Pfam PF00237 Ribosomal protein L22p/L17e 6 107 5.4E-35 T 12-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 MIM_c39660 a8c5d9a68c7d1a5650bbcb29a60b9cfc 109 Gene3D G3DSA:3.90.470.10 1 109 3.1E-41 T 12-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 MIM_c39660 a8c5d9a68c7d1a5650bbcb29a60b9cfc 109 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 1.6E-43 T 12-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c39660 a8c5d9a68c7d1a5650bbcb29a60b9cfc 109 SUPERFAMILY SSF54843 1 107 1.18E-38 T 12-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 MIM_c39660 a8c5d9a68c7d1a5650bbcb29a60b9cfc 109 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 12-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MIM_c39660 a8c5d9a68c7d1a5650bbcb29a60b9cfc 109 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 109 24.18 T 12-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c35310 b168c82f9e21c5cd0879cf5aa9177493 84 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 4 68 3.1E-17 T 12-10-2018 IPR022789 Antitoxin ParD MIM_c35310 b168c82f9e21c5cd0879cf5aa9177493 84 SUPERFAMILY SSF47598 1 45 2.56E-7 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 MIM_c35310 b168c82f9e21c5cd0879cf5aa9177493 84 TIGRFAM TIGR02606 antidote_CC2985: putative addiction module antidote protein, CC2985 family 4 73 1.6E-22 T 12-10-2018 IPR022789 Antitoxin ParD MIM_c35310 b168c82f9e21c5cd0879cf5aa9177493 84 Gene3D G3DSA:1.10.8.1250 10 83 2.2E-18 T 12-10-2018 IPR038296 Antitoxin ParD superfamily MIM_c24950 8586f942e3fc822cd1bc6061368127c0 329 Gene3D G3DSA:3.40.190.10 128 252 3.8E-95 T 12-10-2018 MIM_c24950 8586f942e3fc822cd1bc6061368127c0 329 PIRSF PIRSF017082 1 326 5.0E-75 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c24950 8586f942e3fc822cd1bc6061368127c0 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 323 4.1E-66 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c24950 8586f942e3fc822cd1bc6061368127c0 329 Gene3D G3DSA:3.40.190.150 32 318 3.8E-95 T 12-10-2018 MIM_c24950 8586f942e3fc822cd1bc6061368127c0 329 SUPERFAMILY SSF53850 107 287 3.98E-6 T 12-10-2018 MIM_c23450 a73c59bdd4a95c366c3671f4783e51c5 88 Gene3D G3DSA:2.30.170.50 1 82 9.9E-21 T 12-10-2018 MIM_c23450 a73c59bdd4a95c366c3671f4783e51c5 88 Pfam PF01197 Ribosomal protein L31 1 78 1.6E-24 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c23450 a73c59bdd4a95c366c3671f4783e51c5 88 SUPERFAMILY SSF143800 1 78 5.89E-18 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c23450 a73c59bdd4a95c366c3671f4783e51c5 88 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 78 1.8E-15 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c23450 a73c59bdd4a95c366c3671f4783e51c5 88 PRINTS PR01249 Ribosomal protein L31 signature 59 77 7.6E-13 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c23450 a73c59bdd4a95c366c3671f4783e51c5 88 PRINTS PR01249 Ribosomal protein L31 signature 2 19 7.6E-13 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c23450 a73c59bdd4a95c366c3671f4783e51c5 88 PRINTS PR01249 Ribosomal protein L31 signature 44 59 7.6E-13 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c23450 a73c59bdd4a95c366c3671f4783e51c5 88 ProSitePatterns PS01143 Ribosomal protein L31 signature. 48 69 - T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c33000 55201b942ef5bd1b15a12d2a67f1afa8 364 SUPERFAMILY SSF52540 91 324 1.27E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c33000 55201b942ef5bd1b15a12d2a67f1afa8 364 Pfam PF01883 Iron-sulfur cluster assembly protein 7 68 2.5E-6 T 12-10-2018 IPR002744 MIP18 family-like MIM_c33000 55201b942ef5bd1b15a12d2a67f1afa8 364 Gene3D G3DSA:3.40.50.300 85 338 2.2E-85 T 12-10-2018 MIM_c33000 55201b942ef5bd1b15a12d2a67f1afa8 364 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 97 339 2.6E-101 T 12-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 MIM_c33000 55201b942ef5bd1b15a12d2a67f1afa8 364 ProSitePatterns PS01215 Mrp family signature. 203 219 - T 12-10-2018 IPR000808 Mrp, conserved site GO:0005524 MIM_c33000 55201b942ef5bd1b15a12d2a67f1afa8 364 Hamap MF_02040 Iron-sulfur cluster carrier protein. 92 340 37.165 T 12-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein MIM_c02600 dbfec09bf8a77be9c3058a4ff0d1e307 206 Pfam PF13649 Methyltransferase domain 50 145 8.0E-10 T 12-10-2018 MIM_c02600 dbfec09bf8a77be9c3058a4ff0d1e307 206 Gene3D G3DSA:3.40.50.150 13 193 3.3E-21 T 12-10-2018 MIM_c02600 dbfec09bf8a77be9c3058a4ff0d1e307 206 SUPERFAMILY SSF53335 27 188 2.23E-21 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c35420 160621673e14917f011614f9756a792b 331 PIRSF PIRSF017082 1 331 2.6E-74 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c35420 160621673e14917f011614f9756a792b 331 SUPERFAMILY SSF53850 126 294 6.6E-15 T 12-10-2018 MIM_c35420 160621673e14917f011614f9756a792b 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 55 328 4.0E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c35420 160621673e14917f011614f9756a792b 331 Gene3D G3DSA:3.40.190.150 36 320 1.7E-102 T 12-10-2018 MIM_c35420 160621673e14917f011614f9756a792b 331 Gene3D G3DSA:3.40.190.10 133 256 1.7E-102 T 12-10-2018 MIM_c18000 05c3d7697de7f84283b3bdeffb85dd57 180 SUPERFAMILY SSF53271 8 177 6.82E-34 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like MIM_c18000 05c3d7697de7f84283b3bdeffb85dd57 180 Gene3D G3DSA:3.40.50.2020 9 178 5.7E-32 T 12-10-2018 MIM_c18000 05c3d7697de7f84283b3bdeffb85dd57 180 Pfam PF00156 Phosphoribosyl transferase domain 14 161 2.0E-24 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MIM_c32990 50a951c469692a43789e5819a55cee55 593 Gene3D G3DSA:2.40.160.50 282 592 1.8E-48 T 12-10-2018 MIM_c32990 50a951c469692a43789e5819a55cee55 593 Pfam PF01103 Surface antigen 309 593 3.5E-21 T 12-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 MIM_c32990 50a951c469692a43789e5819a55cee55 593 Gene3D G3DSA:3.10.20.310 185 281 2.7E-9 T 12-10-2018 MIM_c32990 50a951c469692a43789e5819a55cee55 593 Pfam PF17243 POTRA domain TamA domain 1 33 106 4.5E-7 T 12-10-2018 IPR035243 TamA, POTRA domain 1 MIM_c26140 021cc7b5c9db01883d307e901264dfc6 763 Gene3D G3DSA:3.40.50.300 13 177 1.4E-98 T 12-10-2018 MIM_c26140 021cc7b5c9db01883d307e901264dfc6 763 Pfam PF13177 DNA polymerase III, delta subunit 20 178 1.4E-38 T 12-10-2018 MIM_c26140 021cc7b5c9db01883d307e901264dfc6 763 Gene3D G3DSA:1.20.272.10 242 360 4.7E-29 T 12-10-2018 MIM_c26140 021cc7b5c9db01883d307e901264dfc6 763 SUPERFAMILY SSF52540 33 223 7.83E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c26140 021cc7b5c9db01883d307e901264dfc6 763 SMART SM00382 37 179 3.7E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c26140 021cc7b5c9db01883d307e901264dfc6 763 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 355 6.4E-124 T 12-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 MIM_c26140 021cc7b5c9db01883d307e901264dfc6 763 SUPERFAMILY SSF48019 243 358 1.29E-24 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MIM_c26140 021cc7b5c9db01883d307e901264dfc6 763 Pfam PF12170 DNA polymerase III tau subunit V interacting with alpha 636 755 4.6E-5 T 12-10-2018 IPR021029 DNA polymerase III, tau subunit, domain V GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MIM_c26140 021cc7b5c9db01883d307e901264dfc6 763 Gene3D G3DSA:1.10.8.60 8 240 1.4E-98 T 12-10-2018 MIM_c26140 021cc7b5c9db01883d307e901264dfc6 763 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 233 358 1.8E-19 T 12-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 MIM_c02430 cd400a99d30bf385f0e0ccbeb7eec559 421 SUPERFAMILY SSF53474 162 417 3.42E-62 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c02430 cd400a99d30bf385f0e0ccbeb7eec559 421 Gene3D G3DSA:3.40.50.1820 158 419 2.6E-67 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c02430 cd400a99d30bf385f0e0ccbeb7eec559 421 SUPERFAMILY SSF69118 8 140 2.88E-29 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c02430 cd400a99d30bf385f0e0ccbeb7eec559 421 Pfam PF02627 Carboxymuconolactone decarboxylase family 39 124 8.8E-16 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c02430 cd400a99d30bf385f0e0ccbeb7eec559 421 Pfam PF00561 alpha/beta hydrolase fold 178 404 2.9E-22 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c02430 cd400a99d30bf385f0e0ccbeb7eec559 421 PRINTS PR00111 Alpha/beta hydrolase fold signature 261 274 1.1E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c02430 cd400a99d30bf385f0e0ccbeb7eec559 421 PRINTS PR00111 Alpha/beta hydrolase fold signature 247 260 1.1E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c02430 cd400a99d30bf385f0e0ccbeb7eec559 421 PRINTS PR00111 Alpha/beta hydrolase fold signature 203 218 1.1E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c02430 cd400a99d30bf385f0e0ccbeb7eec559 421 PRINTS PR00111 Alpha/beta hydrolase fold signature 362 376 1.1E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c02430 cd400a99d30bf385f0e0ccbeb7eec559 421 Gene3D G3DSA:1.20.1290.10 8 132 5.5E-35 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c01460 20fb3b6bc52d06d5626407d04ce66721 417 Pfam PF07690 Major Facilitator Superfamily 20 344 6.9E-17 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c01460 20fb3b6bc52d06d5626407d04ce66721 417 Gene3D G3DSA:1.20.1250.20 9 198 1.5E-8 T 12-10-2018 MIM_c01460 20fb3b6bc52d06d5626407d04ce66721 417 SUPERFAMILY SSF103473 7 390 5.62E-40 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c01460 20fb3b6bc52d06d5626407d04ce66721 417 Gene3D G3DSA:1.20.1250.20 199 390 8.3E-15 T 12-10-2018 MIM_c32640 05cf740b361274e017d684ed31dd8a57 265 Gene3D G3DSA:3.30.572.10 2 265 3.2E-131 T 12-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MIM_c32640 05cf740b361274e017d684ed31dd8a57 265 Pfam PF00303 Thymidylate synthase 3 265 5.9E-126 T 12-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MIM_c32640 05cf740b361274e017d684ed31dd8a57 265 ProSitePatterns PS00091 Thymidylate synthase active site. 127 155 - T 12-10-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MIM_c32640 05cf740b361274e017d684ed31dd8a57 265 Hamap MF_00008 Thymidylate synthase [thyA]. 2 265 39.955 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MIM_c32640 05cf740b361274e017d684ed31dd8a57 265 PRINTS PR00108 Thymidylate synthase family signature 142 157 4.3E-47 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MIM_c32640 05cf740b361274e017d684ed31dd8a57 265 PRINTS PR00108 Thymidylate synthase family signature 43 64 4.3E-47 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MIM_c32640 05cf740b361274e017d684ed31dd8a57 265 PRINTS PR00108 Thymidylate synthase family signature 160 186 4.3E-47 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MIM_c32640 05cf740b361274e017d684ed31dd8a57 265 PRINTS PR00108 Thymidylate synthase family signature 116 135 4.3E-47 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MIM_c32640 05cf740b361274e017d684ed31dd8a57 265 PRINTS PR00108 Thymidylate synthase family signature 198 215 4.3E-47 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MIM_c32640 05cf740b361274e017d684ed31dd8a57 265 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 3 85 2.8E-39 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MIM_c32640 05cf740b361274e017d684ed31dd8a57 265 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 86 265 6.7E-96 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MIM_c32640 05cf740b361274e017d684ed31dd8a57 265 SUPERFAMILY SSF55831 2 265 1.57E-129 T 12-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MIM_c22900 f92f5ad087c49f29877c7c7117059db8 198 Pfam PF00691 OmpA family 94 188 2.8E-17 T 12-10-2018 IPR006665 OmpA-like domain MIM_c22900 f92f5ad087c49f29877c7c7117059db8 198 SUPERFAMILY SSF103088 82 194 1.96E-29 T 12-10-2018 IPR036737 OmpA-like domain superfamily MIM_c22900 f92f5ad087c49f29877c7c7117059db8 198 Gene3D G3DSA:3.30.1330.60 58 197 2.4E-30 T 12-10-2018 IPR036737 OmpA-like domain superfamily MIM_c02450 c41f2b657081b81e6bdc7764b58acfcb 826 Gene3D G3DSA:2.140.10.10 311 589 2.1E-78 T 12-10-2018 MIM_c02450 c41f2b657081b81e6bdc7764b58acfcb 826 Gene3D G3DSA:2.140.10.10 160 310 1.8E-33 T 12-10-2018 MIM_c02450 c41f2b657081b81e6bdc7764b58acfcb 826 Pfam PF01011 PQQ enzyme repeat 473 499 1.7E-6 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat MIM_c02450 c41f2b657081b81e6bdc7764b58acfcb 826 Pfam PF01011 PQQ enzyme repeat 226 257 1.7E-6 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat MIM_c02450 c41f2b657081b81e6bdc7764b58acfcb 826 Pfam PF01011 PQQ enzyme repeat 751 784 6.7E-5 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat MIM_c02450 c41f2b657081b81e6bdc7764b58acfcb 826 TIGRFAM TIGR03074 PQQ_membr_DH: membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family 17 819 0.0 T 12-10-2018 IPR017511 PQQ-dependent membrane bound dehydrogenase GO:0016021|GO:0016614|GO:0048038|GO:0055114 MIM_c02450 c41f2b657081b81e6bdc7764b58acfcb 826 SUPERFAMILY SSF50998 167 805 1.57E-142 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MIM_c02450 c41f2b657081b81e6bdc7764b58acfcb 826 Gene3D G3DSA:2.140.10.10 590 820 7.3E-37 T 12-10-2018 MIM_c02450 c41f2b657081b81e6bdc7764b58acfcb 826 SMART SM00564 439 489 25.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c02450 c41f2b657081b81e6bdc7764b58acfcb 826 SMART SM00564 666 713 45.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c02450 c41f2b657081b81e6bdc7764b58acfcb 826 SMART SM00564 370 411 96.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c02450 c41f2b657081b81e6bdc7764b58acfcb 826 SMART SM00564 221 252 0.002 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c02450 c41f2b657081b81e6bdc7764b58acfcb 826 SMART SM00564 313 345 150.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c02450 c41f2b657081b81e6bdc7764b58acfcb 826 SMART SM00564 742 774 0.0028 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c12120 28d0663624abdce0fbd17a4d4b842792 255 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 50 252 5.3E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c12120 28d0663624abdce0fbd17a4d4b842792 255 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 30 107 6.5E-17 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c12120 28d0663624abdce0fbd17a4d4b842792 255 SUPERFAMILY SSF161098 31 237 5.1E-41 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c12120 28d0663624abdce0fbd17a4d4b842792 255 Gene3D G3DSA:1.10.3720.10 17 252 1.5E-48 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c19960 0c6f356a8cd47c3cdaf0070c550939b5 405 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 240 253 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 MIM_c19960 0c6f356a8cd47c3cdaf0070c550939b5 405 Pfam PF00155 Aminotransferase class I and II 36 396 7.2E-69 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MIM_c19960 0c6f356a8cd47c3cdaf0070c550939b5 405 Gene3D G3DSA:3.90.1150.10 31 395 4.1E-125 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c19960 0c6f356a8cd47c3cdaf0070c550939b5 405 Gene3D G3DSA:3.40.640.10 67 290 4.1E-125 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c19960 0c6f356a8cd47c3cdaf0070c550939b5 405 SUPERFAMILY SSF53383 8 399 1.22E-103 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c22200 d4333c3758a85ef601dff0b07d4cf9a6 1237 Pfam PF13116 Protein of unknown function 434 715 1.7E-35 T 12-10-2018 IPR025263 Domain of unknown function DUF3971 MIM_c22200 d4333c3758a85ef601dff0b07d4cf9a6 1237 Pfam PF13502 AsmA-like C-terminal region 971 1208 2.4E-40 T 12-10-2018 IPR032712 AsmA-like, C-terminal MIM_c04540 54b0e96f30e58d620c44504cdc0e4230 533 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 37 478 6.9E-157 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c04540 54b0e96f30e58d620c44504cdc0e4230 533 PRINTS PR01165 Cytochrome c oxidase subunit I signature 102 126 1.4E-120 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c04540 54b0e96f30e58d620c44504cdc0e4230 533 PRINTS PR01165 Cytochrome c oxidase subunit I signature 359 377 1.4E-120 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c04540 54b0e96f30e58d620c44504cdc0e4230 533 PRINTS PR01165 Cytochrome c oxidase subunit I signature 300 315 1.4E-120 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c04540 54b0e96f30e58d620c44504cdc0e4230 533 PRINTS PR01165 Cytochrome c oxidase subunit I signature 75 98 1.4E-120 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c04540 54b0e96f30e58d620c44504cdc0e4230 533 PRINTS PR01165 Cytochrome c oxidase subunit I signature 174 192 1.4E-120 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c04540 54b0e96f30e58d620c44504cdc0e4230 533 PRINTS PR01165 Cytochrome c oxidase subunit I signature 324 345 1.4E-120 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c04540 54b0e96f30e58d620c44504cdc0e4230 533 PRINTS PR01165 Cytochrome c oxidase subunit I signature 254 275 1.4E-120 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c04540 54b0e96f30e58d620c44504cdc0e4230 533 PRINTS PR01165 Cytochrome c oxidase subunit I signature 437 458 1.4E-120 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c04540 54b0e96f30e58d620c44504cdc0e4230 533 PRINTS PR01165 Cytochrome c oxidase subunit I signature 28 53 1.4E-120 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c04540 54b0e96f30e58d620c44504cdc0e4230 533 PRINTS PR01165 Cytochrome c oxidase subunit I signature 145 157 1.4E-120 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c04540 54b0e96f30e58d620c44504cdc0e4230 533 PRINTS PR01165 Cytochrome c oxidase subunit I signature 203 222 1.4E-120 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c04540 54b0e96f30e58d620c44504cdc0e4230 533 PRINTS PR01165 Cytochrome c oxidase subunit I signature 387 406 1.4E-120 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c04540 54b0e96f30e58d620c44504cdc0e4230 533 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 256 310 - T 12-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c04540 54b0e96f30e58d620c44504cdc0e4230 533 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 29 532 1.9E-217 T 12-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 MIM_c04540 54b0e96f30e58d620c44504cdc0e4230 533 Gene3D G3DSA:1.20.210.10 16 533 3.0E-223 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c04540 54b0e96f30e58d620c44504cdc0e4230 533 SUPERFAMILY SSF81442 25 532 1.7E-196 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c26160 74fb98374ed96d1e9180ca8b7f89921a 895 Pfam PF12705 PD-(D/E)XK nuclease superfamily 632 867 9.8E-21 T 12-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type MIM_c26160 74fb98374ed96d1e9180ca8b7f89921a 895 TIGRFAM TIGR03623 TIGR03623: probable DNA repair protein 21 888 1.8E-206 T 12-10-2018 IPR019925 DNA repair protein, predicted MIM_c26160 74fb98374ed96d1e9180ca8b7f89921a 895 SUPERFAMILY SSF52540 227 563 1.12E-13 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c35070 4348ecf0cc427f69dc6dd8b279933177 2013 Pfam PF05593 RHS Repeat 1176 1208 1.2E-4 T 12-10-2018 IPR031325 RHS repeat MIM_c35070 4348ecf0cc427f69dc6dd8b279933177 2013 Pfam PF05593 RHS Repeat 1297 1330 1.5E-4 T 12-10-2018 IPR031325 RHS repeat MIM_c35070 4348ecf0cc427f69dc6dd8b279933177 2013 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1807 1875 8.8E-23 T 12-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 MIM_c35070 4348ecf0cc427f69dc6dd8b279933177 2013 Pfam PF03527 RHS protein 1767 1799 2.2E-12 T 12-10-2018 IPR001826 RHS protein MIM_c35070 4348ecf0cc427f69dc6dd8b279933177 2013 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1150 1188 7.1E-5 T 12-10-2018 IPR006530 YD repeat MIM_c35070 4348ecf0cc427f69dc6dd8b279933177 2013 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1255 1292 6.7E-4 T 12-10-2018 IPR006530 YD repeat MIM_c35070 4348ecf0cc427f69dc6dd8b279933177 2013 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1192 1230 2.4E-4 T 12-10-2018 IPR006530 YD repeat MIM_c35070 4348ecf0cc427f69dc6dd8b279933177 2013 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1171 1211 1.9E-7 T 12-10-2018 IPR006530 YD repeat MIM_c35070 4348ecf0cc427f69dc6dd8b279933177 2013 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1234 1275 1.4E-6 T 12-10-2018 IPR006530 YD repeat MIM_c35070 4348ecf0cc427f69dc6dd8b279933177 2013 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1645 1678 2.2E-4 T 12-10-2018 IPR006530 YD repeat MIM_c35070 4348ecf0cc427f69dc6dd8b279933177 2013 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1298 1337 1.7E-5 T 12-10-2018 IPR006530 YD repeat MIM_c35070 4348ecf0cc427f69dc6dd8b279933177 2013 Gene3D G3DSA:2.30.110.50 9 329 1.9E-101 T 12-10-2018 MIM_c35070 4348ecf0cc427f69dc6dd8b279933177 2013 SUPERFAMILY SSF69349 440 649 1.88E-26 T 12-10-2018 MIM_c35070 4348ecf0cc427f69dc6dd8b279933177 2013 Gene3D G3DSA:2.40.50.230 353 455 3.7E-42 T 12-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily MIM_c35070 4348ecf0cc427f69dc6dd8b279933177 2013 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 18 503 2.9E-130 T 12-10-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein MIM_c35070 4348ecf0cc427f69dc6dd8b279933177 2013 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 10 519 1.7E-173 T 12-10-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset MIM_c35070 4348ecf0cc427f69dc6dd8b279933177 2013 SUPERFAMILY SSF50998 1103 1384 8.63E-5 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MIM_c35070 4348ecf0cc427f69dc6dd8b279933177 2013 Pfam PF05954 Phage late control gene D protein (GPD) 23 326 5.9E-84 T 12-10-2018 MIM_c35070 4348ecf0cc427f69dc6dd8b279933177 2013 Gene3D G3DSA:3.55.50.10 94 184 1.9E-101 T 12-10-2018 MIM_c35070 4348ecf0cc427f69dc6dd8b279933177 2013 SUPERFAMILY SSF69255 363 450 1.36E-31 T 12-10-2018 MIM_c35070 4348ecf0cc427f69dc6dd8b279933177 2013 Gene3D G3DSA:3.30.1920.30 220 283 1.9E-101 T 12-10-2018 MIM_c35070 4348ecf0cc427f69dc6dd8b279933177 2013 SUPERFAMILY SSF69279 11 180 4.25E-51 T 12-10-2018 MIM_c35070 4348ecf0cc427f69dc6dd8b279933177 2013 Gene3D G3DSA:2.180.10.10 1242 1499 2.0E-11 T 12-10-2018 MIM_c35070 4348ecf0cc427f69dc6dd8b279933177 2013 Gene3D G3DSA:2.180.10.10 1591 1875 1.0E-38 T 12-10-2018 MIM_c35070 4348ecf0cc427f69dc6dd8b279933177 2013 SUPERFAMILY SSF69279 183 361 4.42E-32 T 12-10-2018 MIM_c13050 4a2f67c59b1bf4db5ca8238f254b7e64 343 SUPERFAMILY SSF143865 30 270 1.83E-43 T 12-10-2018 MIM_c13050 4a2f67c59b1bf4db5ca8238f254b7e64 343 Gene3D G3DSA:3.30.460.20 16 148 5.6E-15 T 12-10-2018 MIM_c13050 4a2f67c59b1bf4db5ca8238f254b7e64 343 Gene3D G3DSA:1.20.58.340 150 265 4.7E-18 T 12-10-2018 MIM_c13050 4a2f67c59b1bf4db5ca8238f254b7e64 343 SUPERFAMILY SSF144083 279 340 6.8E-20 T 12-10-2018 MIM_c13050 4a2f67c59b1bf4db5ca8238f254b7e64 343 Pfam PF01544 CorA-like Mg2+ transporter protein 53 339 4.1E-53 T 12-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 MIM_c13050 4a2f67c59b1bf4db5ca8238f254b7e64 343 Gene3D G3DSA:1.20.58.340 267 343 3.1E-23 T 12-10-2018 MIM_c37250 30d90340ff73a6dab1b0c58eedc9dac3 267 Pfam PF03649 Uncharacterised protein family (UPF0014) 12 251 7.4E-88 T 12-10-2018 IPR005226 UPF0014 family MIM_c37250 30d90340ff73a6dab1b0c58eedc9dac3 267 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 12 252 2.1E-63 T 12-10-2018 IPR005226 UPF0014 family MIM_c35840 a4c3788dda9eb4b1de0e3a69ebffd2b4 217 SUPERFAMILY SSF100950 7 212 6.42E-63 T 12-10-2018 IPR037171 NagB/RpiA transferase-like MIM_c35840 a4c3788dda9eb4b1de0e3a69ebffd2b4 217 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 47 55 - T 12-10-2018 IPR004164 Coenzyme A transferase active site GO:0008410 Reactome: R-HSA-77108 MIM_c35840 a4c3788dda9eb4b1de0e3a69ebffd2b4 217 Pfam PF01144 Coenzyme A transferase 9 203 4.8E-37 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MIM_c35840 a4c3788dda9eb4b1de0e3a69ebffd2b4 217 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 7 211 2.0E-86 T 12-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 MIM_c35840 a4c3788dda9eb4b1de0e3a69ebffd2b4 217 Gene3D G3DSA:3.40.1080.10 4 215 2.1E-82 T 12-10-2018 MIM_c35840 a4c3788dda9eb4b1de0e3a69ebffd2b4 217 SMART SM00882 9 206 1.5E-63 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MIM_c30770 b441b86bb7c1b9816c98f145bf290217 492 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 249 256 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MIM_c30770 b441b86bb7c1b9816c98f145bf290217 492 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MIM_c30770 b441b86bb7c1b9816c98f145bf290217 492 Gene3D G3DSA:3.40.309.10 254 447 1.3E-181 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MIM_c30770 b441b86bb7c1b9816c98f145bf290217 492 SUPERFAMILY SSF53720 2 480 2.23E-168 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c30770 b441b86bb7c1b9816c98f145bf290217 492 Gene3D G3DSA:3.40.605.10 8 475 1.3E-181 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c30770 b441b86bb7c1b9816c98f145bf290217 492 Pfam PF00171 Aldehyde dehydrogenase family 19 477 7.4E-177 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c14130 440dda790f82734811986c837f07b56c 136 SUPERFAMILY SSF89919 9 115 8.76E-25 T 12-10-2018 IPR023799 Ribosome-binding factor A domain superfamily MIM_c14130 440dda790f82734811986c837f07b56c 136 Gene3D G3DSA:3.30.300.20 6 106 3.0E-23 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta MIM_c14130 440dda790f82734811986c837f07b56c 136 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 10 114 3.5E-19 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 MIM_c14130 440dda790f82734811986c837f07b56c 136 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 14 99 6.0E-37 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 MIM_c14130 440dda790f82734811986c837f07b56c 136 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 10 112 20.242 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 MIM_c14130 440dda790f82734811986c837f07b56c 136 Pfam PF02033 Ribosome-binding factor A 11 112 4.1E-22 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 MIM_c06690 20e3afc1807b55560e1e89e204df054f 269 SUPERFAMILY SSF56219 3 266 1.15E-42 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MIM_c06690 20e3afc1807b55560e1e89e204df054f 269 Gene3D G3DSA:3.60.10.10 2 269 6.7E-42 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MIM_c06690 20e3afc1807b55560e1e89e204df054f 269 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 7 259 3.5E-11 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase MIM_c32790 e924ecb79efcd6974189e1e8ba8a48cf 512 SUPERFAMILY SSF53323 14 226 2.48E-9 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 MIM_c32790 e924ecb79efcd6974189e1e8ba8a48cf 512 Gene3D G3DSA:3.40.920.10 11 225 9.6E-8 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 MIM_c32790 e924ecb79efcd6974189e1e8ba8a48cf 512 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 21 208 1.0E-13 T 12-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 MIM_c40970 96c11ec8863cf4a13f0dbb7f2397e512 170 Pfam PF00583 Acetyltransferase (GNAT) family 66 154 1.2E-7 T 12-10-2018 IPR000182 GNAT domain MIM_c40970 96c11ec8863cf4a13f0dbb7f2397e512 170 SUPERFAMILY SSF55729 36 159 2.88E-17 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c40970 96c11ec8863cf4a13f0dbb7f2397e512 170 Gene3D G3DSA:3.40.630.30 30 165 4.0E-17 T 12-10-2018 MIM_c13260 576e3f6a1c5c247703e30a03aa022c52 238 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 11 230 4.6E-84 T 12-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MIM_c13260 576e3f6a1c5c247703e30a03aa022c52 238 SUPERFAMILY SSF46548 108 235 2.62E-38 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MIM_c13260 576e3f6a1c5c247703e30a03aa022c52 238 Gene3D G3DSA:3.10.20.30 1 107 1.0E-37 T 12-10-2018 IPR012675 Beta-grasp domain superfamily MIM_c13260 576e3f6a1c5c247703e30a03aa022c52 238 Gene3D G3DSA:1.10.1060.10 108 238 2.4E-57 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MIM_c13260 576e3f6a1c5c247703e30a03aa022c52 238 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 149 160 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MIM_c13260 576e3f6a1c5c247703e30a03aa022c52 238 Pfam PF13534 4Fe-4S dicluster domain 148 221 7.5E-10 T 12-10-2018 MIM_c13260 576e3f6a1c5c247703e30a03aa022c52 238 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 8 113 4.6E-32 T 12-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MIM_c13260 576e3f6a1c5c247703e30a03aa022c52 238 SUPERFAMILY SSF54292 5 107 8.83E-29 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MIM_c17120 08a806a12c30f8dd6438bd1c753a6bc1 332 SUPERFAMILY SSF51735 123 290 1.02E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c17120 08a806a12c30f8dd6438bd1c753a6bc1 332 Pfam PF16884 N-terminal domain of oxidoreductase 7 108 9.4E-29 T 12-10-2018 MIM_c17120 08a806a12c30f8dd6438bd1c753a6bc1 332 Pfam PF00107 Zinc-binding dehydrogenase 157 290 3.4E-24 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MIM_c17120 08a806a12c30f8dd6438bd1c753a6bc1 332 SUPERFAMILY SSF50129 1 135 3.0E-29 T 12-10-2018 IPR011032 GroES-like superfamily MIM_c17120 08a806a12c30f8dd6438bd1c753a6bc1 332 Gene3D G3DSA:3.90.180.10 20 328 2.0E-104 T 12-10-2018 MIM_c17120 08a806a12c30f8dd6438bd1c753a6bc1 332 SMART SM00829 18 330 2.3E-4 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MIM_c17120 08a806a12c30f8dd6438bd1c753a6bc1 332 Gene3D G3DSA:3.40.50.720 125 301 2.0E-104 T 12-10-2018 MIM_c09300 3950abbb90a0c46d36e78ff5df6b8067 321 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site MIM_c09300 3950abbb90a0c46d36e78ff5df6b8067 321 Gene3D G3DSA:1.10.600.10 1 321 2.2E-116 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily MIM_c09300 3950abbb90a0c46d36e78ff5df6b8067 321 Pfam PF00348 Polyprenyl synthetase 32 274 2.5E-78 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 MIM_c09300 3950abbb90a0c46d36e78ff5df6b8067 321 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site MIM_c09300 3950abbb90a0c46d36e78ff5df6b8067 321 SUPERFAMILY SSF48576 6 320 2.24E-100 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily MIM_c03870 42602b3f723eb3ec36ac4655eb61c8b7 255 Pfam PF00005 ABC transporter 19 179 2.6E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c03870 42602b3f723eb3ec36ac4655eb61c8b7 255 SMART SM00382 28 227 6.6E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c03870 42602b3f723eb3ec36ac4655eb61c8b7 255 Gene3D G3DSA:3.40.50.300 2 255 3.1E-80 T 12-10-2018 MIM_c03870 42602b3f723eb3ec36ac4655eb61c8b7 255 PIRSF PIRSF039085 1 255 1.8E-115 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MIM_c03870 42602b3f723eb3ec36ac4655eb61c8b7 255 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c03870 42602b3f723eb3ec36ac4655eb61c8b7 255 SUPERFAMILY SSF52540 4 249 5.89E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c39840 b20d1c693eaaf8963d49c79d7d2e947b 199 SUPERFAMILY SSF47413 9 73 3.49E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c39840 b20d1c693eaaf8963d49c79d7d2e947b 199 SUPERFAMILY SSF51182 78 184 9.22E-25 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c39840 b20d1c693eaaf8963d49c79d7d2e947b 199 Gene3D G3DSA:1.10.260.40 4 74 1.1E-14 T 12-10-2018 MIM_c39840 b20d1c693eaaf8963d49c79d7d2e947b 199 Pfam PF07883 Cupin domain 128 185 2.6E-13 T 12-10-2018 IPR013096 Cupin 2, conserved barrel MIM_c39840 b20d1c693eaaf8963d49c79d7d2e947b 199 Gene3D G3DSA:2.60.120.10 80 186 7.5E-26 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c39840 b20d1c693eaaf8963d49c79d7d2e947b 199 SMART SM00530 12 67 1.7E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c39840 b20d1c693eaaf8963d49c79d7d2e947b 199 Pfam PF01381 Helix-turn-helix 13 67 2.5E-12 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c41020 31f49d271d5ca5ba8324d4cd54f77465 628 Pfam PF00005 ABC transporter 24 167 2.8E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c41020 31f49d271d5ca5ba8324d4cd54f77465 628 Gene3D G3DSA:3.40.50.300 2 232 2.9E-58 T 12-10-2018 MIM_c41020 31f49d271d5ca5ba8324d4cd54f77465 628 Gene3D G3DSA:3.40.50.300 368 614 9.1E-64 T 12-10-2018 MIM_c41020 31f49d271d5ca5ba8324d4cd54f77465 628 SUPERFAMILY SSF52540 5 228 6.51E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c41020 31f49d271d5ca5ba8324d4cd54f77465 628 Pfam PF00005 ABC transporter 393 536 1.2E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c41020 31f49d271d5ca5ba8324d4cd54f77465 628 SUPERFAMILY SSF52540 371 597 1.96E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c41020 31f49d271d5ca5ba8324d4cd54f77465 628 SMART SM00382 401 582 6.6E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c41020 31f49d271d5ca5ba8324d4cd54f77465 628 SMART SM00382 33 215 8.2E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c41020 31f49d271d5ca5ba8324d4cd54f77465 628 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c04390 c751d8802574286d3b70091cdb507c7f 548 SUPERFAMILY SSF56801 6 542 9.81E-129 T 12-10-2018 MIM_c04390 c751d8802574286d3b70091cdb507c7f 548 ProSitePatterns PS00455 Putative AMP-binding domain signature. 183 194 - T 12-10-2018 IPR020845 AMP-binding, conserved site MIM_c04390 c751d8802574286d3b70091cdb507c7f 548 Gene3D G3DSA:3.30.300.310 441 545 2.5E-27 T 12-10-2018 MIM_c04390 c751d8802574286d3b70091cdb507c7f 548 Pfam PF13193 AMP-binding enzyme C-terminal domain 455 529 3.5E-12 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MIM_c04390 c751d8802574286d3b70091cdb507c7f 548 Gene3D G3DSA:3.40.50.12780 3 440 2.7E-113 T 12-10-2018 MIM_c04390 c751d8802574286d3b70091cdb507c7f 548 Pfam PF00501 AMP-binding enzyme 19 445 1.3E-84 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MIM_c34900 aefda734d6ea899719709d5a84ff7330 329 Gene3D G3DSA:1.10.3720.10 91 320 6.9E-25 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c34900 aefda734d6ea899719709d5a84ff7330 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 324 1.3E-43 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c34900 aefda734d6ea899719709d5a84ff7330 329 SUPERFAMILY SSF161098 97 310 3.4E-20 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c12960 e2860701c8161f3ed3bb87416a29dc8a 190 PIRSF PIRSF018063 23 189 1.1E-52 T 12-10-2018 IPR014490 DNA-binding protein from starved cells-like MIM_c12960 e2860701c8161f3ed3bb87416a29dc8a 190 Gene3D G3DSA:1.20.1260.10 9 189 2.0E-52 T 12-10-2018 IPR012347 Ferritin-like MIM_c12960 e2860701c8161f3ed3bb87416a29dc8a 190 Pfam PF00210 Ferritin-like domain 50 183 1.9E-29 T 12-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 MIM_c12960 e2860701c8161f3ed3bb87416a29dc8a 190 SUPERFAMILY SSF47240 40 183 1.03E-38 T 12-10-2018 IPR009078 Ferritin-like superfamily MIM_c12790 84caab4c585e372455f973a2532bcf2c 307 Gene3D G3DSA:1.10.10.10 3 93 3.7E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c12790 84caab4c585e372455f973a2532bcf2c 307 Pfam PF03466 LysR substrate binding domain 91 292 5.6E-35 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c12790 84caab4c585e372455f973a2532bcf2c 307 SUPERFAMILY SSF46785 4 86 4.3E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c12790 84caab4c585e372455f973a2532bcf2c 307 Gene3D G3DSA:3.40.190.290 94 297 5.4E-39 T 12-10-2018 MIM_c12790 84caab4c585e372455f973a2532bcf2c 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.1E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c12790 84caab4c585e372455f973a2532bcf2c 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 3.4E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c12790 84caab4c585e372455f973a2532bcf2c 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 3.4E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c12790 84caab4c585e372455f973a2532bcf2c 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 3.4E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c12790 84caab4c585e372455f973a2532bcf2c 307 SUPERFAMILY SSF53850 92 295 3.5E-35 T 12-10-2018 MIM_c06650 af7dd4f3e51c4d55c68c6fe50e76e565 98 Gene3D G3DSA:1.10.260.40 2 96 2.1E-28 T 12-10-2018 MIM_c06650 af7dd4f3e51c4d55c68c6fe50e76e565 98 SMART SM00530 12 67 0.0059 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c06650 af7dd4f3e51c4d55c68c6fe50e76e565 98 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 4 83 2.2E-28 T 12-10-2018 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 MIM_c06650 af7dd4f3e51c4d55c68c6fe50e76e565 98 Pfam PF01381 Helix-turn-helix 20 58 1.2E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c06650 af7dd4f3e51c4d55c68c6fe50e76e565 98 SUPERFAMILY SSF47413 8 90 3.83E-22 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c02200 2c0622c279f4a66e71d00d7c6368e28c 333 Gene3D G3DSA:1.10.3470.10 13 332 2.8E-64 T 12-10-2018 IPR037294 ABC transporter, BtuC-like MIM_c02200 2c0622c279f4a66e71d00d7c6368e28c 333 Pfam PF01032 FecCD transport family 25 326 3.9E-66 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MIM_c02200 2c0622c279f4a66e71d00d7c6368e28c 333 SUPERFAMILY SSF81345 13 326 7.45E-65 T 12-10-2018 IPR037294 ABC transporter, BtuC-like MIM_c13380 bdd983e425a216b47768fcb11bd88ebb 187 PIRSF PIRSF026671 3 186 2.9E-52 T 12-10-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 MIM_c13380 bdd983e425a216b47768fcb11bd88ebb 187 SUPERFAMILY SSF55166 7 174 5.1E-56 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MIM_c13380 bdd983e425a216b47768fcb11bd88ebb 187 Pfam PF01427 D-ala-D-ala dipeptidase 9 184 9.1E-43 T 12-10-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 MIM_c13380 bdd983e425a216b47768fcb11bd88ebb 187 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 9 183 27.089 T 12-10-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 MIM_c13380 bdd983e425a216b47768fcb11bd88ebb 187 Gene3D G3DSA:3.30.1380.10 6 179 1.4E-49 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MIM_c28630 8e5c710968b2329cfdcba15ea65336d6 185 Pfam PF13420 Acetyltransferase (GNAT) domain 7 162 2.3E-23 T 12-10-2018 MIM_c28630 8e5c710968b2329cfdcba15ea65336d6 185 SUPERFAMILY SSF55729 2 167 1.69E-27 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c28630 8e5c710968b2329cfdcba15ea65336d6 185 Gene3D G3DSA:3.40.630.30 5 182 6.8E-48 T 12-10-2018 MIM_c35530 c53cb2abce04b84c41d3eb6d51917942 143 SUPERFAMILY SSF55961 7 140 1.41E-38 T 12-10-2018 MIM_c35530 c53cb2abce04b84c41d3eb6d51917942 143 Gene3D G3DSA:3.30.530.20 2 143 2.0E-43 T 12-10-2018 IPR023393 START-like domain superfamily MIM_c35530 c53cb2abce04b84c41d3eb6d51917942 143 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 19 139 1.8E-25 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like MIM_c17630 115b5bf7c889a5fca0c564d13f3f4d98 472 Gene3D G3DSA:3.40.605.10 22 465 7.3E-156 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c17630 115b5bf7c889a5fca0c564d13f3f4d98 472 Pfam PF00171 Aldehyde dehydrogenase family 21 468 6.4E-146 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c17630 115b5bf7c889a5fca0c564d13f3f4d98 472 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 243 250 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MIM_c17630 115b5bf7c889a5fca0c564d13f3f4d98 472 Gene3D G3DSA:3.40.309.10 247 438 7.3E-156 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MIM_c17630 115b5bf7c889a5fca0c564d13f3f4d98 472 SUPERFAMILY SSF53720 2 470 1.44E-143 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c22620 2edf555d210e180fd21f960c85f44bbf 406 Gene3D G3DSA:3.40.50.2300 152 377 7.8E-118 T 12-10-2018 MIM_c22620 2edf555d210e180fd21f960c85f44bbf 406 Gene3D G3DSA:3.40.50.2300 53 365 7.8E-118 T 12-10-2018 MIM_c22620 2edf555d210e180fd21f960c85f44bbf 406 Pfam PF13458 Periplasmic binding protein 48 376 5.4E-70 T 12-10-2018 IPR028081 Leucine-binding protein domain MIM_c22620 2edf555d210e180fd21f960c85f44bbf 406 SUPERFAMILY SSF53822 34 382 1.37E-81 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c27920 b231430e505586d3fef8ef686c6549e5 499 SUPERFAMILY SSF56601 48 498 3.32E-79 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MIM_c27920 b231430e505586d3fef8ef686c6549e5 499 Gene3D G3DSA:3.40.710.10 306 497 8.3E-53 T 12-10-2018 MIM_c27920 b231430e505586d3fef8ef686c6549e5 499 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 87 479 1.4E-56 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MIM_c27920 b231430e505586d3fef8ef686c6549e5 499 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 89 108 5.7E-19 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MIM_c27920 b231430e505586d3fef8ef686c6549e5 499 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 321 343 5.7E-19 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MIM_c27920 b231430e505586d3fef8ef686c6549e5 499 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 379 393 5.7E-19 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MIM_c27920 b231430e505586d3fef8ef686c6549e5 499 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 394 408 5.7E-19 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MIM_c27920 b231430e505586d3fef8ef686c6549e5 499 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 456 469 5.7E-19 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MIM_c27920 b231430e505586d3fef8ef686c6549e5 499 Gene3D G3DSA:3.40.710.10 47 213 2.8E-9 T 12-10-2018 MIM_c27920 b231430e505586d3fef8ef686c6549e5 499 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 78 496 5.2E-79 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MIM_c38170 81e2cb9d09e02b23825604542846b319 256 SUPERFAMILY SSF52540 10 250 1.4E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c38170 81e2cb9d09e02b23825604542846b319 256 SMART SM00382 33 229 1.6E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c38170 81e2cb9d09e02b23825604542846b319 256 Pfam PF00005 ABC transporter 24 181 8.4E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c38170 81e2cb9d09e02b23825604542846b319 256 Gene3D G3DSA:3.40.50.300 4 255 2.3E-70 T 12-10-2018 MIM_c38170 81e2cb9d09e02b23825604542846b319 256 PIRSF PIRSF039085 5 256 1.3E-103 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MIM_c38170 81e2cb9d09e02b23825604542846b319 256 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c38050 e7b17ade64040365c06fbc3071fe2622 275 PIRSF PIRSF029288 1 273 5.7E-86 T 12-10-2018 IPR009211 Predicted virulence protein, SciE type MIM_c38050 e7b17ade64040365c06fbc3071fe2622 275 SUPERFAMILY SSF144059 9 271 7.85E-80 T 12-10-2018 MIM_c38050 e7b17ade64040365c06fbc3071fe2622 275 Pfam PF07024 ImpE protein 143 268 2.1E-45 T 12-10-2018 IPR009211 Predicted virulence protein, SciE type MIM_c38050 e7b17ade64040365c06fbc3071fe2622 275 Gene3D G3DSA:1.25.40.10 8 89 8.6E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MIM_c35480 e9adcaa65a253094c8bb06b0b2263691 279 Gene3D G3DSA:1.10.3720.10 69 277 1.1E-17 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c35480 e9adcaa65a253094c8bb06b0b2263691 279 SUPERFAMILY SSF161098 78 260 9.29E-23 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c35480 e9adcaa65a253094c8bb06b0b2263691 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 276 1.3E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c05130 dc9d1e9ae153ba5016076addb6b2306a 285 SUPERFAMILY SSF81345 13 272 5.23E-26 T 12-10-2018 IPR037294 ABC transporter, BtuC-like MIM_c05130 dc9d1e9ae153ba5016076addb6b2306a 285 Pfam PF00950 ABC 3 transport family 16 274 1.0E-53 T 12-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 MIM_c21410 7a3b1a3d04a66f6027578306458778da 253 SUPERFAMILY SSF54106 52 94 6.67E-11 T 12-10-2018 MIM_c21410 7a3b1a3d04a66f6027578306458778da 253 Pfam PF01551 Peptidase family M23 153 246 3.4E-29 T 12-10-2018 IPR016047 Peptidase M23 MIM_c21410 7a3b1a3d04a66f6027578306458778da 253 SUPERFAMILY SSF51261 115 250 5.75E-42 T 12-10-2018 IPR011055 Duplicated hybrid motif MIM_c21410 7a3b1a3d04a66f6027578306458778da 253 Gene3D G3DSA:2.70.70.10 128 253 1.2E-34 T 12-10-2018 IPR011055 Duplicated hybrid motif MIM_c21410 7a3b1a3d04a66f6027578306458778da 253 SMART SM00257 52 95 5.1E-15 T 12-10-2018 IPR018392 LysM domain MIM_c21410 7a3b1a3d04a66f6027578306458778da 253 Pfam PF01476 LysM domain 53 94 4.2E-15 T 12-10-2018 IPR018392 LysM domain MIM_c21410 7a3b1a3d04a66f6027578306458778da 253 Gene3D G3DSA:3.10.350.10 51 101 2.4E-16 T 12-10-2018 IPR036779 LysM domain superfamily MIM_c29810 2d7e7fcc06c251b68800e682b2c466d1 296 SUPERFAMILY SSF54862 92 279 4.74E-20 T 12-10-2018 MIM_c29810 2d7e7fcc06c251b68800e682b2c466d1 296 Gene3D G3DSA:3.30.70.20 191 240 9.0E-7 T 12-10-2018 MIM_c29810 2d7e7fcc06c251b68800e682b2c466d1 296 Gene3D G3DSA:3.30.70.20 251 291 2.7E-5 T 12-10-2018 MIM_c29810 2d7e7fcc06c251b68800e682b2c466d1 296 Pfam PF12801 4Fe-4S binding domain 173 217 3.6E-6 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MIM_c29810 2d7e7fcc06c251b68800e682b2c466d1 296 Pfam PF12801 4Fe-4S binding domain 84 127 2.9E-12 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MIM_c29810 2d7e7fcc06c251b68800e682b2c466d1 296 Pfam PF13187 4Fe-4S dicluster domain 224 271 1.1E-7 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MIM_c29810 2d7e7fcc06c251b68800e682b2c466d1 296 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 258 269 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MIM_c29810 2d7e7fcc06c251b68800e682b2c466d1 296 TIGRFAM TIGR02163 napH_: ferredoxin-type protein, NapH/MauN family 23 276 1.7E-99 T 12-10-2018 IPR011886 Ferredoxin-type protein, NapH/MauN family MIM_c24000 2b45a3a6e6655fcdeecd841fe1733294 208 Hamap MF_01207 Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ [msrQ]. 10 205 20.758 T 12-10-2018 IPR022837 Protein-methionine-sulfoxide reductase subunit MsrQ GO:0005887|GO:0030091 MIM_c24000 2b45a3a6e6655fcdeecd841fe1733294 208 Pfam PF01794 Ferric reductase like transmembrane component 51 163 1.3E-13 T 12-10-2018 IPR013130 Ferric reductase transmembrane component-like domain MIM_c13870 8b0ac24e6cee5170a8c1ad44d9d3f0f0 250 SUPERFAMILY SSF51735 6 246 1.04E-64 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c13870 8b0ac24e6cee5170a8c1ad44d9d3f0f0 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 246 4.2E-46 T 12-10-2018 MIM_c13870 8b0ac24e6cee5170a8c1ad44d9d3f0f0 250 Gene3D G3DSA:3.40.50.720 2 249 1.6E-62 T 12-10-2018 MIM_c13870 8b0ac24e6cee5170a8c1ad44d9d3f0f0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.7E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c13870 8b0ac24e6cee5170a8c1ad44d9d3f0f0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.7E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c13870 8b0ac24e6cee5170a8c1ad44d9d3f0f0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.7E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c13870 8b0ac24e6cee5170a8c1ad44d9d3f0f0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.7E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c13870 8b0ac24e6cee5170a8c1ad44d9d3f0f0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.7E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c13870 8b0ac24e6cee5170a8c1ad44d9d3f0f0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 2.7E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c21720 48a0a2df72ab0ba8e9095a17b5d7ff3e 194 Pfam PF04264 YceI-like domain 29 191 2.3E-35 T 12-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MIM_c21720 48a0a2df72ab0ba8e9095a17b5d7ff3e 194 Gene3D G3DSA:2.40.128.110 26 193 5.1E-42 T 12-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily MIM_c21720 48a0a2df72ab0ba8e9095a17b5d7ff3e 194 SMART SM00867 28 192 3.4E-47 T 12-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MIM_c21720 48a0a2df72ab0ba8e9095a17b5d7ff3e 194 SUPERFAMILY SSF101874 27 192 1.31E-45 T 12-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily MIM_c35770 7f0c2ac6b06f858870cec6c34f89bf6d 290 Pfam PF00248 Aldo/keto reductase family 19 287 4.7E-49 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain MIM_c35770 7f0c2ac6b06f858870cec6c34f89bf6d 290 SUPERFAMILY SSF51430 14 286 7.46E-64 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MIM_c35770 7f0c2ac6b06f858870cec6c34f89bf6d 290 Gene3D G3DSA:3.20.20.100 9 289 1.7E-64 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MIM_c25400 2fc82544ddb367ddd2d6422311e52ce2 301 SUPERFAMILY SSF53474 5 269 7.97E-56 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c25400 2fc82544ddb367ddd2d6422311e52ce2 301 Pfam PF00561 alpha/beta hydrolase fold 22 257 3.4E-19 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c25400 2fc82544ddb367ddd2d6422311e52ce2 301 Gene3D G3DSA:3.40.50.1820 3 278 1.1E-56 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c00290 e35ef0b583012c42b563924dfa1af1da 317 Gene3D G3DSA:3.40.190.10 120 243 3.1E-109 T 12-10-2018 MIM_c00290 e35ef0b583012c42b563924dfa1af1da 317 Gene3D G3DSA:3.40.190.150 24 308 3.1E-109 T 12-10-2018 MIM_c00290 e35ef0b583012c42b563924dfa1af1da 317 SUPERFAMILY SSF53850 47 280 1.9E-9 T 12-10-2018 MIM_c00290 e35ef0b583012c42b563924dfa1af1da 317 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 43 314 1.4E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c00290 e35ef0b583012c42b563924dfa1af1da 317 PIRSF PIRSF017082 1 317 1.0E-85 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c29650 ee18ceff058b000932c57ec0c4581812 86 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 85 28.155 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c29650 ee18ceff058b000932c57ec0c4581812 86 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 12-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c29650 ee18ceff058b000932c57ec0c4581812 86 Pfam PF01016 Ribosomal L27 protein 2 82 4.3E-37 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c29650 ee18ceff058b000932c57ec0c4581812 86 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 82 4.6E-39 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c29650 ee18ceff058b000932c57ec0c4581812 86 Gene3D G3DSA:2.40.50.1030 6 85 4.0E-29 T 12-10-2018 MIM_c29650 ee18ceff058b000932c57ec0c4581812 86 SUPERFAMILY SSF110324 2 81 5.23E-33 T 12-10-2018 MIM_c29650 ee18ceff058b000932c57ec0c4581812 86 PRINTS PR00063 Ribosomal protein L27 signature 29 53 2.8E-37 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c29650 ee18ceff058b000932c57ec0c4581812 86 PRINTS PR00063 Ribosomal protein L27 signature 4 28 2.8E-37 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c29650 ee18ceff058b000932c57ec0c4581812 86 PRINTS PR00063 Ribosomal protein L27 signature 54 78 2.8E-37 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c29650 ee18ceff058b000932c57ec0c4581812 86 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 70 9.0E-16 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c30450 9a9c8b20b66b0ce740dc9cfdddf5058b 227 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 217 3.7E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c30450 9a9c8b20b66b0ce740dc9cfdddf5058b 227 Gene3D G3DSA:1.10.3720.10 2 218 3.1E-44 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c30450 9a9c8b20b66b0ce740dc9cfdddf5058b 227 SUPERFAMILY SSF161098 11 202 2.88E-35 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c30450 9a9c8b20b66b0ce740dc9cfdddf5058b 227 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 9 105 4.3E-22 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c20570 795739076c196b9fb11d50272e3ae662 343 PIRSF PIRSF017082 15 340 4.5E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c20570 795739076c196b9fb11d50272e3ae662 343 Gene3D G3DSA:3.40.190.10 146 268 3.2E-93 T 12-10-2018 MIM_c20570 795739076c196b9fb11d50272e3ae662 343 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 68 338 8.5E-67 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c20570 795739076c196b9fb11d50272e3ae662 343 Gene3D G3DSA:3.40.190.150 49 332 3.2E-93 T 12-10-2018 MIM_c20570 795739076c196b9fb11d50272e3ae662 343 SUPERFAMILY SSF53850 139 305 1.63E-9 T 12-10-2018 MIM_c04350 36d849b99a8aafb600cb0d0331f283a9 296 Gene3D G3DSA:3.40.1410.10 94 248 2.3E-29 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MIM_c04350 36d849b99a8aafb600cb0d0331f283a9 296 Pfam PF07702 UTRA domain 120 250 4.8E-21 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MIM_c04350 36d849b99a8aafb600cb0d0331f283a9 296 SUPERFAMILY SSF64288 83 259 5.0E-34 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MIM_c04350 36d849b99a8aafb600cb0d0331f283a9 296 Pfam PF00392 Bacterial regulatory proteins, gntR family 33 95 1.3E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c04350 36d849b99a8aafb600cb0d0331f283a9 296 SUPERFAMILY SSF46785 28 97 8.44E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c04350 36d849b99a8aafb600cb0d0331f283a9 296 SMART SM00345 36 95 4.2E-20 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c04350 36d849b99a8aafb600cb0d0331f283a9 296 SMART SM00866 116 255 7.3E-16 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MIM_c04350 36d849b99a8aafb600cb0d0331f283a9 296 Gene3D G3DSA:1.10.10.10 27 93 2.1E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c04350 36d849b99a8aafb600cb0d0331f283a9 296 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 69 3.5E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c04350 36d849b99a8aafb600cb0d0331f283a9 296 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 69 85 3.5E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c34430 1008817d045db03d4e9fede093359f53 279 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 182 267 3.8E-5 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal MIM_c34430 1008817d045db03d4e9fede093359f53 279 Gene3D G3DSA:3.30.465.10 58 175 4.7E-34 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MIM_c34430 1008817d045db03d4e9fede093359f53 279 SUPERFAMILY SSF56176 1 174 2.8E-45 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MIM_c34430 1008817d045db03d4e9fede093359f53 279 Gene3D G3DSA:3.30.390.50 179 277 1.7E-11 T 12-10-2018 MIM_c34430 1008817d045db03d4e9fede093359f53 279 SUPERFAMILY SSF55447 179 272 5.89E-14 T 12-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily MIM_c34430 1008817d045db03d4e9fede093359f53 279 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 174 3.1E-39 T 12-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 MIM_c34430 1008817d045db03d4e9fede093359f53 279 SMART SM01092 181 270 6.1E-11 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal MIM_c34430 1008817d045db03d4e9fede093359f53 279 Gene3D G3DSA:3.30.43.10 1 57 6.4E-21 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 MIM_c34850 077a666c7a7e18de804b42633d94b078 172 Pfam PF08002 Protein of unknown function (DUF1697) 1 132 4.6E-41 T 12-10-2018 IPR012545 Protein of unknown function DUF1697 MIM_c34850 077a666c7a7e18de804b42633d94b078 172 PIRSF PIRSF008502 1 170 3.9E-39 T 12-10-2018 IPR012545 Protein of unknown function DUF1697 MIM_c34850 077a666c7a7e18de804b42633d94b078 172 Gene3D G3DSA:3.30.70.1280 1 88 4.0E-24 T 12-10-2018 MIM_c34850 077a666c7a7e18de804b42633d94b078 172 SUPERFAMILY SSF160379 1 167 2.35E-47 T 12-10-2018 MIM_c25410 508cc3e5664b69da772e671319936da6 324 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 247 7.3E-38 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MIM_c25410 508cc3e5664b69da772e671319936da6 324 SUPERFAMILY SSF51735 1 322 1.43E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c25410 508cc3e5664b69da772e671319936da6 324 Gene3D G3DSA:3.40.50.720 1 320 5.8E-58 T 12-10-2018 MIM_c09210 a0f71c888da3981daf787893c3af3c49 206 Gene3D G3DSA:3.40.50.300 2 206 1.6E-57 T 12-10-2018 MIM_c09210 a0f71c888da3981daf787893c3af3c49 206 SUPERFAMILY SSF52540 3 201 5.61E-32 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c09210 a0f71c888da3981daf787893c3af3c49 206 Pfam PF01121 Dephospho-CoA kinase 4 179 1.4E-52 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 MIM_c09210 a0f71c888da3981daf787893c3af3c49 206 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 195 25.476 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 MIM_c09210 a0f71c888da3981daf787893c3af3c49 206 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 190 7.9E-46 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 MIM_c27310 7abc1dd3614870dfaa0bc91ba8add336 311 Gene3D G3DSA:3.40.50.720 1 188 1.2E-56 T 12-10-2018 MIM_c27310 7abc1dd3614870dfaa0bc91ba8add336 311 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 188 278 3.4E-13 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MIM_c27310 7abc1dd3614870dfaa0bc91ba8add336 311 SUPERFAMILY SSF51735 5 185 6.85E-53 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c27310 7abc1dd3614870dfaa0bc91ba8add336 311 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 184 3.3E-51 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MIM_c27310 7abc1dd3614870dfaa0bc91ba8add336 311 Gene3D G3DSA:1.10.1040.10 189 310 6.0E-32 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MIM_c27310 7abc1dd3614870dfaa0bc91ba8add336 311 SUPERFAMILY SSF48179 188 288 3.15E-14 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c38770 2fcefb7d2f2ba3842212330a5e53b3e7 237 SUPERFAMILY SSF46626 147 235 1.43E-20 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c38770 2fcefb7d2f2ba3842212330a5e53b3e7 237 PIRSF PIRSF000005 5 237 1.7E-57 T 12-10-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 MIM_c38770 2fcefb7d2f2ba3842212330a5e53b3e7 237 SUPERFAMILY SSF46626 35 130 1.41E-17 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c38770 2fcefb7d2f2ba3842212330a5e53b3e7 237 Pfam PF00034 Cytochrome c 149 232 3.3E-7 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c38770 2fcefb7d2f2ba3842212330a5e53b3e7 237 Pfam PF00034 Cytochrome c 38 131 5.7E-9 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c38770 2fcefb7d2f2ba3842212330a5e53b3e7 237 Gene3D G3DSA:1.10.760.10 33 130 1.0E-18 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c38770 2fcefb7d2f2ba3842212330a5e53b3e7 237 Gene3D G3DSA:1.10.760.10 141 236 1.6E-25 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c04960 94703c92107d92eec5b27af9719ce5cd 261 Gene3D G3DSA:3.40.1390.30 18 247 2.9E-72 T 12-10-2018 MIM_c04960 94703c92107d92eec5b27af9719ce5cd 261 SUPERFAMILY SSF102705 6 260 5.1E-69 T 12-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily MIM_c04960 94703c92107d92eec5b27af9719ce5cd 261 Gene3D G3DSA:3.40.1390.30 100 232 2.9E-72 T 12-10-2018 MIM_c04960 94703c92107d92eec5b27af9719ce5cd 261 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 6 259 1.6E-54 T 12-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 MIM_c04960 94703c92107d92eec5b27af9719ce5cd 261 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 9 248 1.4E-49 T 12-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 MIM_c32940 16317aafdabce5cc3aabad130d1e17ae 539 Gene3D G3DSA:1.10.3290.10 182 403 1.2E-23 T 12-10-2018 IPR036597 Fido-like domain superfamily MIM_c32940 16317aafdabce5cc3aabad130d1e17ae 539 Pfam PF02661 Fic/DOC family 241 345 3.1E-12 T 12-10-2018 IPR003812 Fido domain MIM_c32940 16317aafdabce5cc3aabad130d1e17ae 539 SUPERFAMILY SSF140931 227 381 6.28E-16 T 12-10-2018 IPR036597 Fido-like domain superfamily MIM_c25680 92d47417ef9c2ae23b338e18b7202657 179 PIRSF PIRSF029505 3 179 5.9E-62 T 12-10-2018 IPR016922 Uncharacterised conserved protein UCP029505 MIM_c16500 e4a52fb5921d05e264bc2d0b3e497c86 308 SUPERFAMILY SSF52768 2 307 1.87E-99 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily MIM_c16500 e4a52fb5921d05e264bc2d0b3e497c86 308 Gene3D G3DSA:3.40.800.20 1 308 2.4E-118 T 12-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MIM_c16500 e4a52fb5921d05e264bc2d0b3e497c86 308 Pfam PF00850 Histone deacetylase domain 20 305 2.7E-83 T 12-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MIM_c16500 e4a52fb5921d05e264bc2d0b3e497c86 308 PRINTS PR01270 Histone deacetylase superfamily signature 235 245 4.0E-18 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MIM_c16500 e4a52fb5921d05e264bc2d0b3e497c86 308 PRINTS PR01270 Histone deacetylase superfamily signature 157 172 4.0E-18 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MIM_c16500 e4a52fb5921d05e264bc2d0b3e497c86 308 PRINTS PR01270 Histone deacetylase superfamily signature 123 146 4.0E-18 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MIM_c03430 94c1b578a530ff3c7c804c369ffc96dd 343 Gene3D G3DSA:3.40.190.10 143 266 9.7E-98 T 12-10-2018 MIM_c03430 94c1b578a530ff3c7c804c369ffc96dd 343 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 66 338 6.8E-71 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c03430 94c1b578a530ff3c7c804c369ffc96dd 343 Gene3D G3DSA:3.40.190.150 46 332 9.7E-98 T 12-10-2018 MIM_c03430 94c1b578a530ff3c7c804c369ffc96dd 343 PIRSF PIRSF017082 13 341 2.3E-73 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c03430 94c1b578a530ff3c7c804c369ffc96dd 343 SUPERFAMILY SSF53850 131 296 1.45E-9 T 12-10-2018 MIM_c26950 5bb13e7f74ad7d4b4a67e0b2f2de222a 239 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 25 145 4.9E-45 T 12-10-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 MIM_c26950 5bb13e7f74ad7d4b4a67e0b2f2de222a 239 SUPERFAMILY SSF49354 21 145 4.71E-43 T 12-10-2018 IPR008962 PapD-like superfamily MIM_c26950 5bb13e7f74ad7d4b4a67e0b2f2de222a 239 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 101 118 - T 12-10-2018 IPR018046 Pili assembly chaperone, conserved site MIM_c26950 5bb13e7f74ad7d4b4a67e0b2f2de222a 239 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 170 230 1.0E-14 T 12-10-2018 IPR016148 Pili assembly chaperone, C-terminal MIM_c26950 5bb13e7f74ad7d4b4a67e0b2f2de222a 239 Gene3D G3DSA:2.60.40.10 26 146 1.4E-43 T 12-10-2018 IPR013783 Immunoglobulin-like fold MIM_c26950 5bb13e7f74ad7d4b4a67e0b2f2de222a 239 SUPERFAMILY SSF49584 152 232 1.31E-14 T 12-10-2018 IPR036316 Pili assembly chaperone, C-terminal domain superfamily MIM_c26950 5bb13e7f74ad7d4b4a67e0b2f2de222a 239 PRINTS PR00969 Pili chaperone signature 74 95 1.7E-36 T 12-10-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MIM_c26950 5bb13e7f74ad7d4b4a67e0b2f2de222a 239 PRINTS PR00969 Pili chaperone signature 102 119 1.7E-36 T 12-10-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MIM_c26950 5bb13e7f74ad7d4b4a67e0b2f2de222a 239 PRINTS PR00969 Pili chaperone signature 25 34 1.7E-36 T 12-10-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MIM_c26950 5bb13e7f74ad7d4b4a67e0b2f2de222a 239 PRINTS PR00969 Pili chaperone signature 163 178 1.7E-36 T 12-10-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MIM_c26950 5bb13e7f74ad7d4b4a67e0b2f2de222a 239 PRINTS PR00969 Pili chaperone signature 127 142 1.7E-36 T 12-10-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MIM_c26950 5bb13e7f74ad7d4b4a67e0b2f2de222a 239 Gene3D G3DSA:2.60.40.10 148 237 9.5E-14 T 12-10-2018 IPR013783 Immunoglobulin-like fold MIM_c19320 43367a34ff87b106911a199d909c43bf 267 Hamap MF_01974 Methionine aminopeptidase [map]. 2 253 40.226 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MIM_c19320 43367a34ff87b106911a199d909c43bf 267 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 170 188 - T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MIM_c19320 43367a34ff87b106911a199d909c43bf 267 PRINTS PR00599 Methionine aminopeptidase-1 signature 195 207 2.1E-21 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MIM_c19320 43367a34ff87b106911a199d909c43bf 267 PRINTS PR00599 Methionine aminopeptidase-1 signature 94 110 2.1E-21 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MIM_c19320 43367a34ff87b106911a199d909c43bf 267 PRINTS PR00599 Methionine aminopeptidase-1 signature 72 85 2.1E-21 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MIM_c19320 43367a34ff87b106911a199d909c43bf 267 PRINTS PR00599 Methionine aminopeptidase-1 signature 164 176 2.1E-21 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MIM_c19320 43367a34ff87b106911a199d909c43bf 267 Gene3D G3DSA:3.90.230.10 1 258 2.8E-104 T 12-10-2018 MIM_c19320 43367a34ff87b106911a199d909c43bf 267 Pfam PF00557 Metallopeptidase family M24 12 244 1.4E-54 T 12-10-2018 IPR000994 Peptidase M24 MIM_c19320 43367a34ff87b106911a199d909c43bf 267 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 4 252 9.5E-95 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MIM_c19320 43367a34ff87b106911a199d909c43bf 267 SUPERFAMILY SSF55920 6 252 4.58E-89 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like MIM_c18460 990f92f5d1e3efb05da6749c11f2f3f8 80 Gene3D G3DSA:3.30.110.40 5 80 4.2E-23 T 12-10-2018 IPR036868 TusA-like domain superfamily MIM_c18460 990f92f5d1e3efb05da6749c11f2f3f8 80 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 12 36 - T 12-10-2018 IPR001455 TusA-like domain MIM_c18460 990f92f5d1e3efb05da6749c11f2f3f8 80 Pfam PF01206 Sulfurtransferase TusA 11 76 2.1E-19 T 12-10-2018 IPR001455 TusA-like domain MIM_c18460 990f92f5d1e3efb05da6749c11f2f3f8 80 SUPERFAMILY SSF64307 7 79 1.7E-19 T 12-10-2018 IPR036868 TusA-like domain superfamily MIM_c31370 1fa5121b801d5f8d5d708dccc3a7ef98 272 Pfam PF03466 LysR substrate binding domain 63 259 3.3E-35 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c31370 1fa5121b801d5f8d5d708dccc3a7ef98 272 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 36 3.0E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c31370 1fa5121b801d5f8d5d708dccc3a7ef98 272 SUPERFAMILY SSF46785 1 51 5.17E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c31370 1fa5121b801d5f8d5d708dccc3a7ef98 272 SUPERFAMILY SSF53850 65 262 2.33E-31 T 12-10-2018 MIM_c31370 1fa5121b801d5f8d5d708dccc3a7ef98 272 Gene3D G3DSA:3.40.190.290 65 267 3.0E-40 T 12-10-2018 MIM_c31370 1fa5121b801d5f8d5d708dccc3a7ef98 272 Gene3D G3DSA:1.10.10.10 1 63 6.1E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c04520 fcca995049c4a384fab7151a5d7cdede 284 Pfam PF00293 NUDIX domain 130 243 6.2E-10 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MIM_c04520 fcca995049c4a384fab7151a5d7cdede 284 Pfam PF15916 Domain of unknown function (DUF4743) 23 116 5.8E-6 T 12-10-2018 IPR031804 Domain of unknown function DUF4743 MIM_c04520 fcca995049c4a384fab7151a5d7cdede 284 Gene3D G3DSA:3.30.750.160 25 201 7.7E-42 T 12-10-2018 MIM_c04520 fcca995049c4a384fab7151a5d7cdede 284 Gene3D G3DSA:3.90.79.10 116 259 7.7E-42 T 12-10-2018 MIM_c04520 fcca995049c4a384fab7151a5d7cdede 284 ProSitePatterns PS00893 Nudix box signature. 154 175 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MIM_c04520 fcca995049c4a384fab7151a5d7cdede 284 SUPERFAMILY SSF55811 97 247 1.07E-22 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MIM_c17360 9aa2dbde0cac401494373a3d9b0c5e32 319 Gene3D G3DSA:3.40.190.150 32 311 2.8E-70 T 12-10-2018 MIM_c17360 9aa2dbde0cac401494373a3d9b0c5e32 319 PIRSF PIRSF017082 1 319 5.5E-83 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c17360 9aa2dbde0cac401494373a3d9b0c5e32 319 SUPERFAMILY SSF53850 116 281 8.61E-11 T 12-10-2018 MIM_c17360 9aa2dbde0cac401494373a3d9b0c5e32 319 Gene3D G3DSA:3.40.190.10 129 246 2.8E-70 T 12-10-2018 MIM_c17360 9aa2dbde0cac401494373a3d9b0c5e32 319 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 314 4.0E-33 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c32760 e2cd1014e742029e8399302c9a461207 161 Gene3D G3DSA:3.10.450.50 2 161 6.0E-38 T 12-10-2018 MIM_c32760 e2cd1014e742029e8399302c9a461207 161 SUPERFAMILY SSF54427 4 160 9.56E-39 T 12-10-2018 IPR032710 NTF2-like domain superfamily MIM_c32760 e2cd1014e742029e8399302c9a461207 161 Pfam PF00866 Ring hydroxylating beta subunit 12 149 3.0E-22 T 12-10-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0006725|GO:0055114 MIM_c01770 b545efc4a9ad8d4cebee87b7d68dd532 192 Pfam PF01169 Uncharacterized protein family UPF0016 6 80 2.6E-20 T 12-10-2018 IPR001727 Gdt1 family MIM_c01770 b545efc4a9ad8d4cebee87b7d68dd532 192 Pfam PF01169 Uncharacterized protein family UPF0016 105 179 6.8E-23 T 12-10-2018 IPR001727 Gdt1 family MIM_c38400 fb54baf2d61614bd58215071d4e838f5 297 SUPERFAMILY SSF63829 12 279 1.37E-52 T 12-10-2018 MIM_c38400 fb54baf2d61614bd58215071d4e838f5 297 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 199 216 2.3E-21 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MIM_c38400 fb54baf2d61614bd58215071d4e838f5 297 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 93 114 2.3E-21 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MIM_c38400 fb54baf2d61614bd58215071d4e838f5 297 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 137 159 2.3E-21 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MIM_c38400 fb54baf2d61614bd58215071d4e838f5 297 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 241 259 2.3E-21 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MIM_c38400 fb54baf2d61614bd58215071d4e838f5 297 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 16 33 2.3E-21 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MIM_c38400 fb54baf2d61614bd58215071d4e838f5 297 Gene3D G3DSA:2.120.10.30 3 291 4.7E-75 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MIM_c38400 fb54baf2d61614bd58215071d4e838f5 297 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 15 259 2.1E-63 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region MIM_c04610 4b35bde9dd45d92fad63d20c0f728e7d 300 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 14 291 1.0E-93 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 MIM_c04610 4b35bde9dd45d92fad63d20c0f728e7d 300 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 11 292 19.356 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 MIM_c04610 4b35bde9dd45d92fad63d20c0f728e7d 300 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 66 88 - T 12-10-2018 IPR030470 UbiA prenyltransferase conserved site MIM_c04610 4b35bde9dd45d92fad63d20c0f728e7d 300 Gene3D G3DSA:1.10.357.140 18 181 2.5E-14 T 12-10-2018 MIM_c04610 4b35bde9dd45d92fad63d20c0f728e7d 300 Pfam PF01040 UbiA prenyltransferase family 27 278 1.6E-58 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 MIM_c14640 63c3767ea4213f2d322cccf3e5915e43 177 Pfam PF06271 RDD family 21 165 1.3E-15 T 12-10-2018 IPR010432 RDD MIM_c09550 72b19c7482249f89dbb878f95cec09a6 455 Pfam PF00083 Sugar (and other) transporter 20 411 1.2E-22 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MIM_c09550 72b19c7482249f89dbb878f95cec09a6 455 Gene3D G3DSA:1.20.1250.20 14 433 1.2E-54 T 12-10-2018 MIM_c09550 72b19c7482249f89dbb878f95cec09a6 455 SUPERFAMILY SSF103473 14 434 9.29E-60 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c01300 81a4946cf2eda5609f24d41a0db00ef6 144 SUPERFAMILY SSF54427 6 135 4.01E-30 T 12-10-2018 IPR032710 NTF2-like domain superfamily MIM_c01300 81a4946cf2eda5609f24d41a0db00ef6 144 Pfam PF14534 Domain of unknown function (DUF4440) 13 120 9.8E-12 T 12-10-2018 IPR027843 Domain of unknown function DUF4440 MIM_c01300 81a4946cf2eda5609f24d41a0db00ef6 144 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 8 127 2.9E-14 T 12-10-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 MIM_c01300 81a4946cf2eda5609f24d41a0db00ef6 144 Gene3D G3DSA:3.10.450.50 5 138 5.3E-30 T 12-10-2018 MIM_c12580 0817c081e58a0f857e443c51be74a3dd 486 Pfam PF09190 DALR domain 361 416 4.3E-19 T 12-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 MIM_c12580 0817c081e58a0f857e443c51be74a3dd 486 SUPERFAMILY SSF52374 5 330 5.35E-81 T 12-10-2018 MIM_c12580 0817c081e58a0f857e443c51be74a3dd 486 Gene3D G3DSA:1.20.120.640 324 486 1.3E-39 T 12-10-2018 MIM_c12580 0817c081e58a0f857e443c51be74a3dd 486 SMART SM00840 361 416 3.1E-25 T 12-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 MIM_c12580 0817c081e58a0f857e443c51be74a3dd 486 SUPERFAMILY SSF47323 334 484 3.14E-32 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c12580 0817c081e58a0f857e443c51be74a3dd 486 Gene3D G3DSA:3.40.50.620 1 323 2.9E-117 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c12580 0817c081e58a0f857e443c51be74a3dd 486 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 4 485 36.615 T 12-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 MIM_c12580 0817c081e58a0f857e443c51be74a3dd 486 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 18 331 1.2E-112 T 12-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 MIM_c12580 0817c081e58a0f857e443c51be74a3dd 486 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 4 485 2.4E-152 T 12-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 MIM_c12580 0817c081e58a0f857e443c51be74a3dd 486 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 196 214 2.1E-28 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MIM_c12580 0817c081e58a0f857e443c51be74a3dd 486 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 27 38 2.1E-28 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MIM_c12580 0817c081e58a0f857e443c51be74a3dd 486 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 63 72 2.1E-28 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MIM_c12580 0817c081e58a0f857e443c51be74a3dd 486 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 227 248 2.1E-28 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MIM_c25360 40d7a24bd645e32e8d776888b5907f82 223 SUPERFAMILY SSF46785 9 80 7.94E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c25360 40d7a24bd645e32e8d776888b5907f82 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 76 1.0E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c25360 40d7a24bd645e32e8d776888b5907f82 223 Gene3D G3DSA:1.10.10.10 1 78 6.2E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c25360 40d7a24bd645e32e8d776888b5907f82 223 SMART SM00895 86 210 2.4E-18 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c25360 40d7a24bd645e32e8d776888b5907f82 223 Gene3D G3DSA:1.20.120.530 80 221 1.4E-28 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c25360 40d7a24bd645e32e8d776888b5907f82 223 SUPERFAMILY SSF48008 82 218 2.25E-27 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MIM_c25360 40d7a24bd645e32e8d776888b5907f82 223 SMART SM00345 18 76 3.9E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MIM_c25360 40d7a24bd645e32e8d776888b5907f82 223 Pfam PF07729 FCD domain 86 209 3.7E-25 T 12-10-2018 IPR011711 GntR, C-terminal MIM_c39310 83a0b77acce5993dd12d81d3ca910962 398 Gene3D G3DSA:3.40.50.2300 148 279 7.3E-109 T 12-10-2018 MIM_c39310 83a0b77acce5993dd12d81d3ca910962 398 SUPERFAMILY SSF53822 29 391 1.24E-84 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c39310 83a0b77acce5993dd12d81d3ca910962 398 Pfam PF13458 Periplasmic binding protein 29 364 1.2E-85 T 12-10-2018 IPR028081 Leucine-binding protein domain MIM_c39310 83a0b77acce5993dd12d81d3ca910962 398 Gene3D G3DSA:3.40.50.2300 29 330 7.3E-109 T 12-10-2018 MIM_c20310 d145c4583e6aa22c346e3c3149320ae9 501 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 273 280 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MIM_c20310 d145c4583e6aa22c346e3c3149320ae9 501 Pfam PF00171 Aldehyde dehydrogenase family 37 497 5.7E-177 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c20310 d145c4583e6aa22c346e3c3149320ae9 501 Gene3D G3DSA:3.40.605.10 33 495 9.0E-187 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c20310 d145c4583e6aa22c346e3c3149320ae9 501 Gene3D G3DSA:3.40.309.10 278 467 9.0E-187 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MIM_c20310 d145c4583e6aa22c346e3c3149320ae9 501 SUPERFAMILY SSF53720 28 500 3.27E-170 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c28640 e61b7fd378bc7784f105a3f74fdc76a2 270 SUPERFAMILY SSF88713 6 268 6.67E-49 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MIM_c28640 e61b7fd378bc7784f105a3f74fdc76a2 270 Pfam PF04794 YdjC-like protein 7 258 8.8E-44 T 12-10-2018 IPR006879 Carbohydrate deacetylase YdjC-like MIM_c28640 e61b7fd378bc7784f105a3f74fdc76a2 270 Gene3D G3DSA:3.20.20.370 2 270 6.9E-27 T 12-10-2018 MIM_c31550 8244255bd63f054dc786738d48bc7118 141 SUPERFAMILY SSF46785 31 135 6.82E-32 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c31550 8244255bd63f054dc786738d48bc7118 141 Pfam PF01638 HxlR-like helix-turn-helix 43 129 1.9E-26 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type MIM_c31550 8244255bd63f054dc786738d48bc7118 141 Gene3D G3DSA:1.10.10.10 16 141 3.1E-40 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c36270 c08bc70b7ec6a5e40d985f68cf773dc8 322 Pfam PF12833 Helix-turn-helix domain 230 308 1.3E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c36270 c08bc70b7ec6a5e40d985f68cf773dc8 322 SMART SM00342 224 307 2.9E-23 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c36270 c08bc70b7ec6a5e40d985f68cf773dc8 322 Pfam PF01965 DJ-1/PfpI family 1 170 3.6E-24 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 MIM_c36270 c08bc70b7ec6a5e40d985f68cf773dc8 322 SUPERFAMILY SSF46689 208 255 9.41E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c36270 c08bc70b7ec6a5e40d985f68cf773dc8 322 SUPERFAMILY SSF46689 260 311 2.87E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c36270 c08bc70b7ec6a5e40d985f68cf773dc8 322 Gene3D G3DSA:1.10.10.60 208 311 3.2E-24 T 12-10-2018 MIM_c36270 c08bc70b7ec6a5e40d985f68cf773dc8 322 Gene3D G3DSA:3.40.50.880 1 207 1.4E-62 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c36270 c08bc70b7ec6a5e40d985f68cf773dc8 322 SUPERFAMILY SSF52317 1 190 1.4E-48 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c25130 169f6c66582ad848d78ae882215d8a8b 257 SUPERFAMILY SSF56925 83 257 1.81E-9 T 12-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel MIM_c25130 169f6c66582ad848d78ae882215d8a8b 257 Gene3D G3DSA:2.40.160.20 112 257 2.8E-6 T 12-10-2018 MIM_c25130 169f6c66582ad848d78ae882215d8a8b 257 Pfam PF13505 Outer membrane protein beta-barrel domain 81 257 1.1E-7 T 12-10-2018 IPR027385 Outer membrane protein beta-barrel MIM_c37670 b750924decb2e53e8a3f70ecfd2aa5d0 390 Gene3D G3DSA:3.40.50.2000 47 179 1.3E-5 T 12-10-2018 MIM_c37670 b750924decb2e53e8a3f70ecfd2aa5d0 390 SUPERFAMILY SSF53756 110 348 1.92E-31 T 12-10-2018 MIM_c37670 b750924decb2e53e8a3f70ecfd2aa5d0 390 Pfam PF13692 Glycosyl transferases group 1 203 342 2.4E-12 T 12-10-2018 MIM_c37670 b750924decb2e53e8a3f70ecfd2aa5d0 390 Gene3D G3DSA:3.40.50.2000 182 349 1.5E-22 T 12-10-2018 MIM_c30950 7ecab53568c8d63ef6891d415402e057 128 Pfam PF13744 Helix-turn-helix domain 34 90 4.6E-7 T 12-10-2018 IPR039554 HigA2-like, helix-turn-helix domain MIM_c30950 7ecab53568c8d63ef6891d415402e057 128 SMART SM00530 36 90 9.9E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c30950 7ecab53568c8d63ef6891d415402e057 128 Gene3D G3DSA:1.10.260.40 33 98 1.2E-9 T 12-10-2018 MIM_c30950 7ecab53568c8d63ef6891d415402e057 128 SUPERFAMILY SSF47413 35 96 4.22E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c23410 6e637b5a24b519781fb7a6e277786060 210 TIGRFAM TIGR03035 trp_arylform: arylformamidase 6 210 1.4E-85 T 12-10-2018 IPR017484 Kynurenine formamidase, bacteria GO:0004328|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 MIM_c23410 6e637b5a24b519781fb7a6e277786060 210 Hamap MF_01969 Kynurenine formamidase [kynB]. 5 210 40.19 T 12-10-2018 IPR017484 Kynurenine formamidase, bacteria GO:0004328|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 MIM_c23410 6e637b5a24b519781fb7a6e277786060 210 Gene3D G3DSA:3.50.30.50 1 210 2.9E-62 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 MIM_c23410 6e637b5a24b519781fb7a6e277786060 210 SUPERFAMILY SSF102198 4 208 1.01E-54 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 MIM_c23410 6e637b5a24b519781fb7a6e277786060 210 Pfam PF04199 Putative cyclase 8 153 6.1E-17 T 12-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 MIM_c32540 aeabb10e2b31fed5494ddc367673c136 631 SUPERFAMILY SSF52402 248 619 3.2E-87 T 12-10-2018 MIM_c32540 aeabb10e2b31fed5494ddc367673c136 631 SUPERFAMILY SSF56235 1 222 8.58E-62 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MIM_c32540 aeabb10e2b31fed5494ddc367673c136 631 Gene3D G3DSA:3.60.20.10 1 186 1.3E-60 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MIM_c32540 aeabb10e2b31fed5494ddc367673c136 631 PIRSF PIRSF001589 1 631 6.5E-165 T 12-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MIM_c32540 aeabb10e2b31fed5494ddc367673c136 631 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 560 1.3E-140 T 12-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MIM_c32540 aeabb10e2b31fed5494ddc367673c136 631 Pfam PF00733 Asparagine synthase 254 624 4.3E-111 T 12-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 MIM_c32540 aeabb10e2b31fed5494ddc367673c136 631 Pfam PF13537 Glutamine amidotransferase domain 47 169 1.3E-44 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain MIM_c07560 0be94505697f6ecf0823d35ea401b93a 562 Gene3D G3DSA:3.40.50.1220 188 353 5.2E-33 T 12-10-2018 MIM_c07560 0be94505697f6ecf0823d35ea401b93a 562 Gene3D G3DSA:3.40.50.970 1 181 8.1E-63 T 12-10-2018 MIM_c07560 0be94505697f6ecf0823d35ea401b93a 562 Gene3D G3DSA:3.40.50.970 357 560 5.3E-59 T 12-10-2018 MIM_c07560 0be94505697f6ecf0823d35ea401b93a 562 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 326 9.1E-27 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MIM_c07560 0be94505697f6ecf0823d35ea401b93a 562 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 10 171 9.3E-54 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MIM_c07560 0be94505697f6ecf0823d35ea401b93a 562 SUPERFAMILY SSF52518 369 546 6.61E-59 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c07560 0be94505697f6ecf0823d35ea401b93a 562 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 426 445 - T 12-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 MIM_c07560 0be94505697f6ecf0823d35ea401b93a 562 SUPERFAMILY SSF52518 8 183 2.31E-53 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c07560 0be94505697f6ecf0823d35ea401b93a 562 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 390 536 4.6E-44 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MIM_c07560 0be94505697f6ecf0823d35ea401b93a 562 SUPERFAMILY SSF52467 159 338 7.55E-34 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MIM_c24070 f4e197f36b7323b312424cee81ba0a97 146 Pfam PF12802 MarR family 37 94 6.8E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c24070 f4e197f36b7323b312424cee81ba0a97 146 SMART SM00347 30 130 6.6E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c24070 f4e197f36b7323b312424cee81ba0a97 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 1.3E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c24070 f4e197f36b7323b312424cee81ba0a97 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 1.3E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c24070 f4e197f36b7323b312424cee81ba0a97 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 54 70 1.3E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c24070 f4e197f36b7323b312424cee81ba0a97 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 120 140 1.3E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c24070 f4e197f36b7323b312424cee81ba0a97 146 SUPERFAMILY SSF46785 4 145 1.47E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c24070 f4e197f36b7323b312424cee81ba0a97 146 Gene3D G3DSA:1.10.10.10 2 146 7.5E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c34070 a277569e2dd0f7124313f7ca460b1a07 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 290 2.1E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c34070 a277569e2dd0f7124313f7ca460b1a07 294 SUPERFAMILY SSF161098 98 281 4.32E-24 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c34070 a277569e2dd0f7124313f7ca460b1a07 294 TIGRFAM TIGR01183 ntrB: nitrate ABC transporter, permease protein 87 284 2.0E-68 T 12-10-2018 IPR005889 Nitrate transport permease GO:0015112|GO:0015706|GO:0016021 MIM_c34070 a277569e2dd0f7124313f7ca460b1a07 294 Gene3D G3DSA:1.10.3720.10 101 292 7.7E-20 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c08990 7c0fe5f2ea6132f2bc036487868f6ab4 702 SUPERFAMILY SSF56935 62 702 1.68E-80 T 12-10-2018 MIM_c08990 7c0fe5f2ea6132f2bc036487868f6ab4 702 Pfam PF00593 TonB dependent receptor 228 700 1.1E-24 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MIM_c08990 7c0fe5f2ea6132f2bc036487868f6ab4 702 Gene3D G3DSA:2.40.170.20 59 702 2.3E-96 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MIM_c08990 7c0fe5f2ea6132f2bc036487868f6ab4 702 Pfam PF07715 TonB-dependent Receptor Plug Domain 67 167 3.5E-8 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain MIM_c27450 4d6b2f3b61a52e909aba08f9c133e28b 149 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 145 2.0E-55 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 MIM_c27450 4d6b2f3b61a52e909aba08f9c133e28b 149 Gene3D G3DSA:3.50.80.10 1 149 5.8E-57 T 12-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily MIM_c27450 4d6b2f3b61a52e909aba08f9c133e28b 149 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 146 1.1E-55 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 MIM_c27450 4d6b2f3b61a52e909aba08f9c133e28b 149 SUPERFAMILY SSF69500 1 145 1.1E-54 T 12-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily MIM_c27450 4d6b2f3b61a52e909aba08f9c133e28b 149 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 146 35.006 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 MIM_c01580 678b9caf11ee6a4493fac62ab5e889e9 354 SUPERFAMILY SSF53850 63 273 3.66E-32 T 12-10-2018 MIM_c01580 678b9caf11ee6a4493fac62ab5e889e9 354 Gene3D G3DSA:3.40.190.10 57 321 9.4E-45 T 12-10-2018 MIM_c01580 678b9caf11ee6a4493fac62ab5e889e9 354 Pfam PF09084 NMT1/THI5 like 84 271 3.5E-16 T 12-10-2018 IPR015168 SsuA/THI5-like MIM_c01580 678b9caf11ee6a4493fac62ab5e889e9 354 Gene3D G3DSA:3.40.190.10 124 231 9.4E-45 T 12-10-2018 MIM_c00380 1f24b065c25ddd8a54eb5077b4c9ecba 470 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 8 431 4.6E-162 T 12-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MIM_c00380 1f24b065c25ddd8a54eb5077b4c9ecba 470 Pfam PF00296 Luciferase-like monooxygenase 25 386 9.0E-53 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MIM_c00380 1f24b065c25ddd8a54eb5077b4c9ecba 470 PIRSF PIRSF000337 3 446 7.8E-133 T 12-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MIM_c00380 1f24b065c25ddd8a54eb5077b4c9ecba 470 Gene3D G3DSA:3.20.20.30 2 454 1.6E-141 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MIM_c00380 1f24b065c25ddd8a54eb5077b4c9ecba 470 SUPERFAMILY SSF51679 4 435 3.66E-118 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MIM_c29440 585100bf8b71aa08472fa006b1f8b83a 154 SUPERFAMILY SSF52304 4 145 4.06E-63 T 12-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MIM_c29440 585100bf8b71aa08472fa006b1f8b83a 154 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 154 73.872 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MIM_c29440 585100bf8b71aa08472fa006b1f8b83a 154 Pfam PF01220 Dehydroquinase class II 4 140 1.0E-64 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MIM_c29440 585100bf8b71aa08472fa006b1f8b83a 154 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 4 143 1.0E-63 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MIM_c29440 585100bf8b71aa08472fa006b1f8b83a 154 Gene3D G3DSA:3.40.50.9100 1 152 4.1E-68 T 12-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MIM_c29440 585100bf8b71aa08472fa006b1f8b83a 154 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 18 141 1.0E-43 T 12-10-2018 MIM_c29440 585100bf8b71aa08472fa006b1f8b83a 154 PIRSF PIRSF001399 1 147 3.1E-63 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MIM_c29440 585100bf8b71aa08472fa006b1f8b83a 154 ProSitePatterns PS01029 Dehydroquinase class II signature. 8 25 - T 12-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MIM_c25720 931e854cb86cc5980930c28900838144 252 SMART SM00382 30 211 2.6E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c25720 931e854cb86cc5980930c28900838144 252 Pfam PF00005 ABC transporter 22 162 4.8E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c25720 931e854cb86cc5980930c28900838144 252 Gene3D G3DSA:3.40.50.300 2 241 6.8E-51 T 12-10-2018 MIM_c25720 931e854cb86cc5980930c28900838144 252 SUPERFAMILY SSF52540 3 228 3.37E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c25720 931e854cb86cc5980930c28900838144 252 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c40900 90de2b8d7a74697fe19700a6dcb9cae8 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 312 1.6E-39 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c40900 90de2b8d7a74697fe19700a6dcb9cae8 314 SUPERFAMILY SSF161098 90 298 7.36E-19 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c40900 90de2b8d7a74697fe19700a6dcb9cae8 314 Gene3D G3DSA:1.10.3720.10 84 304 7.0E-24 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c00860 ce95317471f5fb7861f4c0f02075c1ff 268 SUPERFAMILY SSF53955 109 251 1.72E-30 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily MIM_c00860 ce95317471f5fb7861f4c0f02075c1ff 268 Pfam PF01464 Transglycosylase SLT domain 121 223 9.8E-22 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 MIM_c00860 ce95317471f5fb7861f4c0f02075c1ff 268 Gene3D G3DSA:1.10.530.10 113 258 5.8E-28 T 12-10-2018 MIM_c25660 be7e084dae2b35778e1966ef60d22931 329 PIRSF PIRSF018266 5 326 5.3E-83 T 12-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component MIM_c25660 be7e084dae2b35778e1966ef60d22931 329 Gene3D G3DSA:2.60.120.1440 109 252 6.3E-25 T 12-10-2018 MIM_c25660 be7e084dae2b35778e1966ef60d22931 329 Gene3D G3DSA:3.55.50.30 253 328 1.9E-6 T 12-10-2018 MIM_c25660 be7e084dae2b35778e1966ef60d22931 329 Pfam PF04773 FecR protein 120 211 2.4E-18 T 12-10-2018 IPR006860 FecR protein MIM_c25660 be7e084dae2b35778e1966ef60d22931 329 Pfam PF16220 Domain of unknown function (DUF4880) 14 56 1.7E-9 T 12-10-2018 IPR032623 FecR, N-terminal MIM_c38810 686a4275f08dd0e2cdd0a057b673f985 184 Gene3D G3DSA:2.60.120.10 1 183 1.9E-66 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c38810 686a4275f08dd0e2cdd0a057b673f985 184 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 8 176 2.0E-55 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MIM_c38810 686a4275f08dd0e2cdd0a057b673f985 184 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 7 176 4.5E-67 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MIM_c38810 686a4275f08dd0e2cdd0a057b673f985 184 SUPERFAMILY SSF51182 1 181 1.85E-69 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c38810 686a4275f08dd0e2cdd0a057b673f985 184 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 5 177 8.7E-67 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MIM_c17720 c0a6982a16112482ec78bcd367405009 189 SMART SM01007 20 189 1.2E-42 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal MIM_c17720 c0a6982a16112482ec78bcd367405009 189 SUPERFAMILY SSF53639 14 189 2.55E-48 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily MIM_c17720 c0a6982a16112482ec78bcd367405009 189 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 20 189 7.8E-39 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal MIM_c17720 c0a6982a16112482ec78bcd367405009 189 Gene3D G3DSA:3.40.225.10 8 189 1.4E-53 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily MIM_c24580 a57a112531fedc7a89f3571cd79320f4 162 SUPERFAMILY SSF56770 11 155 1.22E-64 T 12-10-2018 MIM_c24580 a57a112531fedc7a89f3571cd79320f4 162 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 13 154 1.1E-74 T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24580 a57a112531fedc7a89f3571cd79320f4 162 Gene3D G3DSA:3.40.50.12280 1 162 5.8E-77 T 12-10-2018 MIM_c24580 a57a112531fedc7a89f3571cd79320f4 162 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 39 148 4.5E-22 T 12-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24580 a57a112531fedc7a89f3571cd79320f4 162 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 2 153 40.546 T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24580 a57a112531fedc7a89f3571cd79320f4 162 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 120 136 - T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c19970 1e46f540870c45b287e8378a7115adb7 355 Gene3D G3DSA:2.120.10.30 46 354 5.1E-96 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MIM_c19970 1e46f540870c45b287e8378a7115adb7 355 SUPERFAMILY SSF63829 36 351 2.4E-66 T 12-10-2018 MIM_c19970 1e46f540870c45b287e8378a7115adb7 355 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 75 339 9.9E-63 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region MIM_c11480 909707558b63f95e5caec1bbcb03e3f4 192 Pfam PF04355 SmpA / OmlA family 43 111 3.4E-22 T 12-10-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 MIM_c11480 909707558b63f95e5caec1bbcb03e3f4 192 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 16 120 25.778 T 12-10-2018 IPR026592 Outer membrane protein assembly factor BamE MIM_c11480 909707558b63f95e5caec1bbcb03e3f4 192 Gene3D G3DSA:3.30.1450.10 42 125 2.0E-25 T 12-10-2018 IPR037873 BamE-like MIM_c25790 2716fd047d2928a7d6179014094d48fe 388 SUPERFAMILY SSF55961 163 376 3.3E-36 T 12-10-2018 MIM_c25790 2716fd047d2928a7d6179014094d48fe 388 Pfam PF00355 Rieske [2Fe-2S] domain 40 129 2.2E-8 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MIM_c25790 2716fd047d2928a7d6179014094d48fe 388 Gene3D G3DSA:3.90.380.10 246 384 2.3E-8 T 12-10-2018 MIM_c25790 2716fd047d2928a7d6179014094d48fe 388 Gene3D G3DSA:2.102.10.10 33 160 1.7E-33 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MIM_c25790 2716fd047d2928a7d6179014094d48fe 388 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 172 373 5.1E-30 T 12-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 MIM_c25790 2716fd047d2928a7d6179014094d48fe 388 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 172 194 2.3E-7 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 MIM_c25790 2716fd047d2928a7d6179014094d48fe 388 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 70 90 2.3E-7 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 MIM_c25790 2716fd047d2928a7d6179014094d48fe 388 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 20 45 2.3E-7 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 MIM_c25790 2716fd047d2928a7d6179014094d48fe 388 Gene3D G3DSA:3.90.380.10 13 215 1.7E-33 T 12-10-2018 MIM_c25790 2716fd047d2928a7d6179014094d48fe 388 SUPERFAMILY SSF50022 11 150 3.27E-26 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MIM_c13170 ed6ce37c6e27e0bd1725baac7afb1192 91 Pfam PF14542 GCN5-related N-acetyl-transferase 13 87 6.0E-24 T 12-10-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase MIM_c13170 ed6ce37c6e27e0bd1725baac7afb1192 91 SUPERFAMILY SSF55729 3 89 5.31E-25 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c13170 ed6ce37c6e27e0bd1725baac7afb1192 91 Gene3D G3DSA:3.40.630.30 1 91 9.7E-24 T 12-10-2018 MIM_c21600 3ab78a5923b4ac38015185119d1b39e0 76 Pfam PF03869 Arc-like DNA binding domain 9 46 3.0E-4 T 12-10-2018 IPR005569 Arc-like DNA binding domain GO:0003677 MIM_c21600 3ab78a5923b4ac38015185119d1b39e0 76 Gene3D G3DSA:1.10.1220.10 10 59 4.1E-19 T 12-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 MIM_c21600 3ab78a5923b4ac38015185119d1b39e0 76 SUPERFAMILY SSF47598 4 69 2.09E-17 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 MIM_c09610 91ffdef702c4d986af64ab71ee716cb2 274 Pfam PF04909 Amidohydrolase 2 273 1.8E-23 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MIM_c09610 91ffdef702c4d986af64ab71ee716cb2 274 SUPERFAMILY SSF51556 2 274 1.63E-48 T 12-10-2018 IPR032466 Metal-dependent hydrolase MIM_c09610 91ffdef702c4d986af64ab71ee716cb2 274 Gene3D G3DSA:3.20.20.140 1 274 1.5E-62 T 12-10-2018 MIM_c05330 7afcc18733bac1f8aabb875b68399d8b 176 Gene3D G3DSA:3.30.428.10 12 145 3.3E-35 T 12-10-2018 IPR036265 HIT-like superfamily MIM_c05330 7afcc18733bac1f8aabb875b68399d8b 176 Pfam PF01230 HIT domain 29 100 8.9E-13 T 12-10-2018 IPR001310 Histidine triad (HIT) protein MIM_c05330 7afcc18733bac1f8aabb875b68399d8b 176 SUPERFAMILY SSF54197 5 122 2.04E-32 T 12-10-2018 IPR036265 HIT-like superfamily MIM_c08190 dbbe3262f9945d73df699d8e6bd2751e 424 Gene3D G3DSA:3.30.70.150 1 133 1.6E-42 T 12-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 MIM_c08190 dbbe3262f9945d73df699d8e6bd2751e 424 SUPERFAMILY SSF51649 134 421 8.9E-84 T 12-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 MIM_c08190 dbbe3262f9945d73df699d8e6bd2751e 424 ProSitePatterns PS00157 Ribulose bisphosphate carboxylase large chain active site. 181 189 - T 12-10-2018 IPR020878 Ribulose bisphosphate carboxylase, large chain, active site GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 MIM_c08190 dbbe3262f9945d73df699d8e6bd2751e 424 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 14 129 1.3E-6 T 12-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 MIM_c08190 dbbe3262f9945d73df699d8e6bd2751e 424 SUPERFAMILY SSF54966 4 133 4.58E-33 T 12-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 MIM_c08190 dbbe3262f9945d73df699d8e6bd2751e 424 Gene3D G3DSA:3.20.20.110 134 423 5.0E-98 T 12-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 MIM_c08190 dbbe3262f9945d73df699d8e6bd2751e 424 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 139 419 2.3E-75 T 12-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 MIM_c39730 5ce133b3611142ea37136d9e5ac91062 330 SUPERFAMILY SSF51569 58 313 1.88E-72 T 12-10-2018 MIM_c39730 5ce133b3611142ea37136d9e5ac91062 330 PIRSF PIRSF001357 58 320 1.7E-69 T 12-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MIM_c39730 5ce133b3611142ea37136d9e5ac91062 330 Gene3D G3DSA:3.20.20.70 55 315 2.8E-87 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c39730 5ce133b3611142ea37136d9e5ac91062 330 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 66 290 3.6E-42 T 12-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MIM_c39730 5ce133b3611142ea37136d9e5ac91062 330 Pfam PF01791 DeoC/LacD family aldolase 68 278 1.3E-21 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MIM_c39730 5ce133b3611142ea37136d9e5ac91062 330 SMART SM01133 64 311 4.1E-70 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MIM_c05500 c670618b55095760a9a2930e8a52ea06 398 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 287 384 9.1E-44 T 12-10-2018 IPR012997 Rare lipoprotein A MIM_c05500 c670618b55095760a9a2930e8a52ea06 398 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 10 377 24.517 T 12-10-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 MIM_c05500 c670618b55095760a9a2930e8a52ea06 398 Pfam PF03330 Lytic transglycolase 285 373 2.1E-24 T 12-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain MIM_c05500 c670618b55095760a9a2930e8a52ea06 398 SUPERFAMILY SSF50685 287 368 7.67E-11 T 12-10-2018 IPR036908 RlpA-like domain superfamily MIM_c05500 c670618b55095760a9a2930e8a52ea06 398 Gene3D G3DSA:2.40.40.10 284 378 2.0E-37 T 12-10-2018 IPR036908 RlpA-like domain superfamily MIM_c07190 71275f296ecacf5e079215cdf07bbc47 212 Pfam PF13419 Haloacid dehalogenase-like hydrolase 11 180 4.9E-27 T 12-10-2018 MIM_c07190 71275f296ecacf5e079215cdf07bbc47 212 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 93 174 7.6E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MIM_c07190 71275f296ecacf5e079215cdf07bbc47 212 Gene3D G3DSA:1.10.150.240 20 84 2.6E-33 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MIM_c07190 71275f296ecacf5e079215cdf07bbc47 212 Gene3D G3DSA:3.40.50.1000 10 202 2.6E-33 T 12-10-2018 IPR023214 HAD superfamily MIM_c07190 71275f296ecacf5e079215cdf07bbc47 212 SUPERFAMILY SSF56784 5 209 1.87E-39 T 12-10-2018 IPR036412 HAD-like superfamily MIM_c38720 7682c865192badc75d7a682e4a84a713 344 Pfam PF13379 NMT1-like family 34 278 2.3E-20 T 12-10-2018 MIM_c38720 7682c865192badc75d7a682e4a84a713 344 Gene3D G3DSA:3.40.190.10 144 337 2.6E-14 T 12-10-2018 MIM_c38720 7682c865192badc75d7a682e4a84a713 344 Gene3D G3DSA:3.40.190.10 32 141 1.8E-11 T 12-10-2018 MIM_c38720 7682c865192badc75d7a682e4a84a713 344 SUPERFAMILY SSF53850 50 280 1.23E-27 T 12-10-2018 MIM_c10920 77a484970773a87eafb7288a1c868271 122 Pfam PF11367 Protein of unknown function (DUF3168) 13 88 5.8E-9 T 12-10-2018 IPR021508 Tail completion protein MIM_c33930 0a64b9b481918de16f00a47437c5a648 434 SUPERFAMILY SSF47203 266 410 7.89E-12 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c33930 0a64b9b481918de16f00a47437c5a648 434 SUPERFAMILY SSF56645 44 248 6.15E-33 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c33930 0a64b9b481918de16f00a47437c5a648 434 Gene3D G3DSA:2.40.110.10 151 250 2.4E-23 T 12-10-2018 MIM_c33930 0a64b9b481918de16f00a47437c5a648 434 PIRSF PIRSF016578 3 415 4.5E-29 T 12-10-2018 MIM_c33930 0a64b9b481918de16f00a47437c5a648 434 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 275 408 4.1E-11 T 12-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain MIM_c33930 0a64b9b481918de16f00a47437c5a648 434 Gene3D G3DSA:1.10.540.10 41 140 3.0E-15 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c33930 0a64b9b481918de16f00a47437c5a648 434 Gene3D G3DSA:1.20.140.10 263 432 3.2E-42 T 12-10-2018 MIM_c15550 1fca7a27dc5a3fb216e2ff22a71b3cac 603 Gene3D G3DSA:3.40.50.300 374 596 8.9E-37 T 12-10-2018 MIM_c15550 1fca7a27dc5a3fb216e2ff22a71b3cac 603 ProSitePatterns PS00211 ABC transporters family signature. 513 527 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c15550 1fca7a27dc5a3fb216e2ff22a71b3cac 603 SMART SM00382 416 595 1.0E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c15550 1fca7a27dc5a3fb216e2ff22a71b3cac 603 Pfam PF00005 ABC transporter 408 541 1.3E-16 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c15550 1fca7a27dc5a3fb216e2ff22a71b3cac 603 Pfam PF06472 ABC transporter transmembrane region 2 36 323 1.3E-78 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MIM_c15550 1fca7a27dc5a3fb216e2ff22a71b3cac 603 SUPERFAMILY SSF90123 57 525 6.54E-17 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MIM_c15550 1fca7a27dc5a3fb216e2ff22a71b3cac 603 SUPERFAMILY SSF52540 391 590 1.36E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c17070 d7c9a49f8680db37ef7b994d99471ad4 316 PIRSF PIRSF017082 1 315 4.4E-62 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c17070 d7c9a49f8680db37ef7b994d99471ad4 316 Gene3D G3DSA:3.40.190.150 22 306 9.9E-95 T 12-10-2018 MIM_c17070 d7c9a49f8680db37ef7b994d99471ad4 316 SUPERFAMILY SSF53850 111 274 1.45E-9 T 12-10-2018 MIM_c17070 d7c9a49f8680db37ef7b994d99471ad4 316 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 42 311 3.5E-74 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c17070 d7c9a49f8680db37ef7b994d99471ad4 316 Gene3D G3DSA:3.40.190.10 119 241 9.9E-95 T 12-10-2018 MIM_c00450 474df85ec9aa9869e7d75b20fe3ba4f4 569 SUPERFAMILY SSF103473 30 347 5.36E-51 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c00450 474df85ec9aa9869e7d75b20fe3ba4f4 569 ProSitePatterns PS00216 Sugar transport proteins signature 1. 316 332 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MIM_c00450 474df85ec9aa9869e7d75b20fe3ba4f4 569 SUPERFAMILY SSF103473 451 567 1.83E-13 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c00450 474df85ec9aa9869e7d75b20fe3ba4f4 569 ProSitePatterns PS00217 Sugar transport proteins signature 2. 144 169 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MIM_c00450 474df85ec9aa9869e7d75b20fe3ba4f4 569 Gene3D G3DSA:1.20.1250.20 445 569 2.5E-14 T 12-10-2018 MIM_c00450 474df85ec9aa9869e7d75b20fe3ba4f4 569 Gene3D G3DSA:1.20.1250.20 32 366 4.9E-52 T 12-10-2018 MIM_c00450 474df85ec9aa9869e7d75b20fe3ba4f4 569 Pfam PF00083 Sugar (and other) transporter 36 344 1.1E-27 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MIM_c00450 474df85ec9aa9869e7d75b20fe3ba4f4 569 Pfam PF00083 Sugar (and other) transporter 466 568 9.0E-8 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MIM_c10160 519e277179a45dda8fd5b96bf1c5e0cf 424 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 414 4.4E-120 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit MIM_c10160 519e277179a45dda8fd5b96bf1c5e0cf 424 PIRSF PIRSF006066 1 424 2.9E-165 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 MIM_c10160 519e277179a45dda8fd5b96bf1c5e0cf 424 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 418 9.3E-138 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 MIM_c25700 8f4688c04d47514e8c4a3be27d16f49d 287 SUPERFAMILY SSF53807 20 281 9.32E-27 T 12-10-2018 MIM_c25700 8f4688c04d47514e8c4a3be27d16f49d 287 Gene3D G3DSA:3.40.50.1980 69 180 1.5E-7 T 12-10-2018 MIM_c25700 8f4688c04d47514e8c4a3be27d16f49d 287 Pfam PF01297 Zinc-uptake complex component A periplasmic 128 263 1.1E-15 T 12-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 MIM_c08770 26c678cdffb2c18986b3896e9c233e74 258 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 25 249 6.8E-63 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c08770 26c678cdffb2c18986b3896e9c233e74 258 SMART SM00062 24 253 2.1E-67 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c08770 26c678cdffb2c18986b3896e9c233e74 258 Gene3D G3DSA:3.40.190.10 26 249 7.9E-78 T 12-10-2018 MIM_c08770 26c678cdffb2c18986b3896e9c233e74 258 TIGRFAM TIGR01096 3A0103s03R: lysine-arginine-ornithine-binding periplasmic protein 7 249 3.0E-78 T 12-10-2018 IPR005768 Specific amino acids and opine-binding periplasmic protein, ABC transporter GO:0030288|GO:0071705 MIM_c08770 26c678cdffb2c18986b3896e9c233e74 258 Gene3D G3DSA:3.40.190.10 110 210 7.9E-78 T 12-10-2018 MIM_c08770 26c678cdffb2c18986b3896e9c233e74 258 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 47 60 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site MIM_c08770 26c678cdffb2c18986b3896e9c233e74 258 SUPERFAMILY SSF53850 1 250 3.8E-65 T 12-10-2018 MIM_c24190 4104438111efc2945649b6e090fb2c7c 273 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 168 2.2E-18 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MIM_c24190 4104438111efc2945649b6e090fb2c7c 273 Pfam PF00633 Helix-hairpin-helix motif 100 127 3.9E-9 T 12-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 MIM_c24190 4104438111efc2945649b6e090fb2c7c 273 Hamap MF_00942 Endonuclease III [nth]. 1 209 35.665 T 12-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 MIM_c24190 4104438111efc2945649b6e090fb2c7c 273 SMART SM00525 186 206 4.2E-5 T 12-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 MIM_c24190 4104438111efc2945649b6e090fb2c7c 273 TIGRFAM TIGR01083 nth: endonuclease III 5 194 1.9E-79 T 12-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 MIM_c24190 4104438111efc2945649b6e090fb2c7c 273 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 12-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 MIM_c24190 4104438111efc2945649b6e090fb2c7c 273 SUPERFAMILY SSF48150 3 212 2.67E-68 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MIM_c24190 4104438111efc2945649b6e090fb2c7c 273 SMART SM00478 38 185 3.2E-55 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MIM_c24190 4104438111efc2945649b6e090fb2c7c 273 Gene3D G3DSA:1.10.1670.10 11 203 1.4E-73 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 MIM_c24190 4104438111efc2945649b6e090fb2c7c 273 Gene3D G3DSA:1.10.340.30 21 132 1.4E-73 T 12-10-2018 MIM_c24190 4104438111efc2945649b6e090fb2c7c 273 PIRSF PIRSF001435 216 266 1100.0 T 12-10-2018 MIM_c24190 4104438111efc2945649b6e090fb2c7c 273 PIRSF PIRSF001435 1 212 4.9E-50 T 12-10-2018 MIM_c15930 20db79c517bbc1d253a5fae072e2dd21 333 PIRSF PIRSF017082 1 333 2.4E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c15930 20db79c517bbc1d253a5fae072e2dd21 333 SUPERFAMILY SSF53850 118 293 5.97E-7 T 12-10-2018 MIM_c15930 20db79c517bbc1d253a5fae072e2dd21 333 Gene3D G3DSA:3.40.190.150 33 323 1.9E-109 T 12-10-2018 MIM_c15930 20db79c517bbc1d253a5fae072e2dd21 333 Gene3D G3DSA:3.40.190.10 131 258 1.9E-109 T 12-10-2018 MIM_c15930 20db79c517bbc1d253a5fae072e2dd21 333 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 326 2.1E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c19690 cb7729c46ea6b49b99a7b8da08f1aab5 299 SUPERFAMILY SSF103481 188 284 4.45E-9 T 12-10-2018 MIM_c19690 cb7729c46ea6b49b99a7b8da08f1aab5 299 SUPERFAMILY SSF103481 48 138 4.18E-5 T 12-10-2018 MIM_c19690 cb7729c46ea6b49b99a7b8da08f1aab5 299 Pfam PF00892 EamA-like transporter family 152 280 3.7E-19 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MIM_c20370 4106f88b9785fb3d6c4902f44be00a27 426 SUPERFAMILY SSF51735 1 160 2.88E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c20370 4106f88b9785fb3d6c4902f44be00a27 426 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 313 414 3.1E-7 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MIM_c20370 4106f88b9785fb3d6c4902f44be00a27 426 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 281 1.2E-23 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MIM_c20370 4106f88b9785fb3d6c4902f44be00a27 426 SUPERFAMILY SSF48179 163 291 6.46E-24 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c20370 4106f88b9785fb3d6c4902f44be00a27 426 Gene3D G3DSA:1.10.1040.10 163 293 2.2E-24 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MIM_c20370 4106f88b9785fb3d6c4902f44be00a27 426 Gene3D G3DSA:1.10.1040.10 310 422 2.0E-9 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MIM_c20370 4106f88b9785fb3d6c4902f44be00a27 426 Gene3D G3DSA:3.40.50.720 1 161 1.3E-43 T 12-10-2018 MIM_c20370 4106f88b9785fb3d6c4902f44be00a27 426 SUPERFAMILY SSF48179 313 417 1.01E-7 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c20370 4106f88b9785fb3d6c4902f44be00a27 426 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 160 3.8E-35 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 MIM_c32050 da75b804fb326fda51a200fe957986fb 187 Pfam PF06496 Protein of unknown function (DUF1097) 14 166 4.7E-25 T 12-10-2018 IPR009476 Protein of unknown function DUF1097 MIM_c12460 5699795922ea8e0805702f7667b18750 302 Pfam PF03466 LysR substrate binding domain 89 295 1.7E-38 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c12460 5699795922ea8e0805702f7667b18750 302 SUPERFAMILY SSF53850 90 299 2.95E-41 T 12-10-2018 MIM_c12460 5699795922ea8e0805702f7667b18750 302 Gene3D G3DSA:1.10.10.10 3 90 3.7E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c12460 5699795922ea8e0805702f7667b18750 302 Gene3D G3DSA:3.40.190.290 92 301 1.9E-38 T 12-10-2018 MIM_c12460 5699795922ea8e0805702f7667b18750 302 SUPERFAMILY SSF46785 1 112 1.11E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c12460 5699795922ea8e0805702f7667b18750 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 2.1E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c12870 06a3b7c3ddc623b8a8ba881d1891a7a0 707 Pfam PF00593 TonB dependent receptor 235 706 8.6E-63 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MIM_c12870 06a3b7c3ddc623b8a8ba881d1891a7a0 707 Gene3D G3DSA:2.40.170.20 173 707 2.8E-126 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MIM_c12870 06a3b7c3ddc623b8a8ba881d1891a7a0 707 SUPERFAMILY SSF56935 29 707 5.86E-131 T 12-10-2018 MIM_c12870 06a3b7c3ddc623b8a8ba881d1891a7a0 707 Pfam PF07715 TonB-dependent Receptor Plug Domain 66 163 3.1E-16 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain MIM_c12870 06a3b7c3ddc623b8a8ba881d1891a7a0 707 Gene3D G3DSA:2.170.130.10 47 172 2.2E-32 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MIM_c12870 06a3b7c3ddc623b8a8ba881d1891a7a0 707 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 67 707 1.6E-112 T 12-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 MIM_c08870 71dc192cc6503a6e2c0985e9dffaf21b 297 Pfam PF00034 Cytochrome c 200 269 7.4E-5 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c08870 71dc192cc6503a6e2c0985e9dffaf21b 297 SUPERFAMILY SSF46626 182 269 3.78E-16 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c08870 71dc192cc6503a6e2c0985e9dffaf21b 297 Gene3D G3DSA:1.10.760.10 92 166 5.3E-15 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c08870 71dc192cc6503a6e2c0985e9dffaf21b 297 SUPERFAMILY SSF46626 97 167 3.32E-14 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c08870 71dc192cc6503a6e2c0985e9dffaf21b 297 Gene3D G3DSA:1.10.760.10 176 268 9.8E-18 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c28220 654b8591fd9c2bd9a89a60781cc55dae 240 Gene3D G3DSA:3.40.50.300 106 219 1.3E-10 T 12-10-2018 MIM_c28220 654b8591fd9c2bd9a89a60781cc55dae 240 SMART SM00382 40 208 4.3E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c28220 654b8591fd9c2bd9a89a60781cc55dae 240 Gene3D G3DSA:3.40.50.300 29 93 8.5E-9 T 12-10-2018 MIM_c28220 654b8591fd9c2bd9a89a60781cc55dae 240 SUPERFAMILY SSF52540 36 204 1.96E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c28220 654b8591fd9c2bd9a89a60781cc55dae 240 Pfam PF13476 AAA domain 37 68 8.5E-9 T 12-10-2018 IPR038729 Rad50/SbcC-type AAA domain MIM_c17500 949cadc175aaa4917078bc78aa9d4643 484 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 256 263 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MIM_c17500 949cadc175aaa4917078bc78aa9d4643 484 SUPERFAMILY SSF53720 6 483 7.85E-172 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c17500 949cadc175aaa4917078bc78aa9d4643 484 Gene3D G3DSA:3.40.605.10 22 475 3.8E-184 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c17500 949cadc175aaa4917078bc78aa9d4643 484 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 32 478 1.1E-215 T 12-10-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 MIM_c17500 949cadc175aaa4917078bc78aa9d4643 484 Pfam PF00171 Aldehyde dehydrogenase family 21 479 6.0E-172 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c17500 949cadc175aaa4917078bc78aa9d4643 484 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 284 295 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MIM_c17500 949cadc175aaa4917078bc78aa9d4643 484 Gene3D G3DSA:3.40.309.10 263 452 3.8E-184 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MIM_c14450 a1fea5e71c61410590085fb7b8aaa18c 200 SUPERFAMILY SSF46626 99 193 5.67E-12 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c14450 a1fea5e71c61410590085fb7b8aaa18c 200 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 111 182 1.0E-8 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c14450 a1fea5e71c61410590085fb7b8aaa18c 200 Gene3D G3DSA:1.10.760.10 75 194 2.1E-9 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c08300 c10937c96b3102b858bb04b85b4f33f8 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 106 6.6E-26 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c08300 c10937c96b3102b858bb04b85b4f33f8 216 SUPERFAMILY SSF161098 12 197 4.8E-39 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c08300 c10937c96b3102b858bb04b85b4f33f8 216 Gene3D G3DSA:1.10.3720.10 6 214 6.3E-45 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c08300 c10937c96b3102b858bb04b85b4f33f8 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 212 1.0E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c15840 6f11da08fc5ba3a469dbb47933702768 191 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 6.3E-21 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c15840 6f11da08fc5ba3a469dbb47933702768 191 PRINTS PR01703 Manganese superoxide dismutase signature 154 166 6.3E-21 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c15840 6f11da08fc5ba3a469dbb47933702768 191 PRINTS PR01703 Manganese superoxide dismutase signature 65 78 6.3E-21 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c15840 6f11da08fc5ba3a469dbb47933702768 191 PRINTS PR01703 Manganese superoxide dismutase signature 117 125 6.3E-21 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c15840 6f11da08fc5ba3a469dbb47933702768 191 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 6.3E-21 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c15840 6f11da08fc5ba3a469dbb47933702768 191 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 88 188 2.1E-39 T 12-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c15840 6f11da08fc5ba3a469dbb47933702768 191 PIRSF PIRSF000349 1 191 1.9E-83 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c15840 6f11da08fc5ba3a469dbb47933702768 191 Gene3D G3DSA:1.10.287.990 20 82 1.3E-24 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c15840 6f11da08fc5ba3a469dbb47933702768 191 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 81 8.4E-32 T 12-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c15840 6f11da08fc5ba3a469dbb47933702768 191 Gene3D G3DSA:2.40.500.20 84 191 2.1E-43 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c15840 6f11da08fc5ba3a469dbb47933702768 191 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 156 163 - T 12-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c15840 6f11da08fc5ba3a469dbb47933702768 191 SUPERFAMILY SSF54719 82 190 2.1E-43 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c15840 6f11da08fc5ba3a469dbb47933702768 191 SUPERFAMILY SSF46609 1 84 6.94E-34 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MIM_c08760 6df7ab2b064f8361f7ab6a3adf5d8dfe 379 Pfam PF10994 Protein of unknown function (DUF2817) 20 360 2.9E-97 T 12-10-2018 IPR021259 Protein of unknown function DUF2817 MIM_c08760 6df7ab2b064f8361f7ab6a3adf5d8dfe 379 SUPERFAMILY SSF53187 52 295 5.62E-19 T 12-10-2018 MIM_c14460 58ab47b6420182d9a06e2a716b0f48d4 615 SMART SM00564 423 490 550.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c14460 58ab47b6420182d9a06e2a716b0f48d4 615 SMART SM00564 500 530 5.2E-5 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c14460 58ab47b6420182d9a06e2a716b0f48d4 615 SMART SM00564 180 217 5.9 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c14460 58ab47b6420182d9a06e2a716b0f48d4 615 SMART SM00564 269 317 29.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c14460 58ab47b6420182d9a06e2a716b0f48d4 615 SMART SM00564 83 115 220.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c14460 58ab47b6420182d9a06e2a716b0f48d4 615 SMART SM00564 134 166 0.08 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c14460 58ab47b6420182d9a06e2a716b0f48d4 615 SUPERFAMILY SSF50998 29 605 4.71E-172 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MIM_c14460 58ab47b6420182d9a06e2a716b0f48d4 615 TIGRFAM TIGR03075 PQQ_enz_alc_DH: PQQ-dependent dehydrogenase, methanol/ethanol family 22 558 1.1E-226 T 12-10-2018 IPR017512 PQQ-dependent dehydrogenase, methanol/ethanol family GO:0005509|GO:0016020|GO:0016614|GO:0055114 MIM_c14460 58ab47b6420182d9a06e2a716b0f48d4 615 ProSitePatterns PS00364 Bacterial quinoprotein dehydrogenases signature 2. 265 286 - T 12-10-2018 IPR001479 Quinoprotein dehydrogenase, conserved site GO:0030288|GO:0055114 MIM_c14460 58ab47b6420182d9a06e2a716b0f48d4 615 Gene3D G3DSA:2.140.10.10 26 614 1.0E-218 T 12-10-2018 MIM_c14460 58ab47b6420182d9a06e2a716b0f48d4 615 Pfam PF01011 PQQ enzyme repeat 505 536 8.5E-7 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat MIM_c14460 58ab47b6420182d9a06e2a716b0f48d4 615 Pfam PF13360 PQQ-like domain 78 221 3.3E-11 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat MIM_c05480 92eb247c9981778d209f550b83de6186 197 Gene3D G3DSA:3.40.50.10490 1 196 9.9E-74 T 12-10-2018 MIM_c05480 92eb247c9981778d209f550b83de6186 197 Pfam PF13580 SIS domain 12 146 5.3E-35 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MIM_c05480 92eb247c9981778d209f550b83de6186 197 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 2 192 36.023 T 12-10-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 MIM_c05480 92eb247c9981778d209f550b83de6186 197 SUPERFAMILY SSF53697 7 192 1.36E-54 T 12-10-2018 MIM_c37610 61bbd63d42876b5a242e7c594ac3bb47 311 Gene3D G3DSA:3.40.50.720 99 284 2.1E-99 T 12-10-2018 MIM_c37610 61bbd63d42876b5a242e7c594ac3bb47 311 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 310 2.6E-25 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 MIM_c37610 61bbd63d42876b5a242e7c594ac3bb47 311 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 286 8.5E-60 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MIM_c37610 61bbd63d42876b5a242e7c594ac3bb47 311 SUPERFAMILY SSF52283 2 133 6.38E-29 T 12-10-2018 MIM_c37610 61bbd63d42876b5a242e7c594ac3bb47 311 Gene3D G3DSA:3.40.50.720 7 308 2.1E-99 T 12-10-2018 MIM_c37610 61bbd63d42876b5a242e7c594ac3bb47 311 SUPERFAMILY SSF51735 102 287 8.52E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c28880 46181710d6ef50b63a3d5c2c2b63fae4 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 1.6E-27 T 12-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 MIM_c28880 46181710d6ef50b63a3d5c2c2b63fae4 104 Gene3D G3DSA:1.10.3730.20 1 104 7.0E-30 T 12-10-2018 MIM_c28880 46181710d6ef50b63a3d5c2c2b63fae4 104 SUPERFAMILY SSF103481 5 103 7.06E-21 T 12-10-2018 MIM_c02650 9d1139883f58aa8f8351533e0640f0da 466 Pfam PF00005 ABC transporter 43 191 1.4E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c02650 9d1139883f58aa8f8351533e0640f0da 466 Gene3D G3DSA:3.40.50.300 3 268 8.4E-67 T 12-10-2018 MIM_c02650 9d1139883f58aa8f8351533e0640f0da 466 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 37 391 4.8E-115 T 12-10-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 MIM_c02650 9d1139883f58aa8f8351533e0640f0da 466 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c02650 9d1139883f58aa8f8351533e0640f0da 466 SMART SM00382 52 240 2.8E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c02650 9d1139883f58aa8f8351533e0640f0da 466 SUPERFAMILY SSF52540 38 263 3.95E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c02650 9d1139883f58aa8f8351533e0640f0da 466 Gene3D G3DSA:3.10.580.10 269 388 6.7E-8 T 12-10-2018 MIM_c02650 9d1139883f58aa8f8351533e0640f0da 466 SUPERFAMILY SSF54631 282 387 5.94E-11 T 12-10-2018 MIM_c18930 ead275edf8b43455e5eef95b1042f057 405 Gene3D G3DSA:3.80.30.20 8 316 1.6E-98 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe MIM_c18930 ead275edf8b43455e5eef95b1042f057 405 SMART SM00729 23 243 2.7E-51 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MIM_c18930 ead275edf8b43455e5eef95b1042f057 405 Pfam PF04055 Radical SAM superfamily 28 195 4.7E-16 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MIM_c18930 ead275edf8b43455e5eef95b1042f057 405 SUPERFAMILY SSF102114 22 399 1.57E-106 T 12-10-2018 MIM_c18930 ead275edf8b43455e5eef95b1042f057 405 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 24 390 1.4E-107 T 12-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 MIM_c18930 ead275edf8b43455e5eef95b1042f057 405 Pfam PF06969 HemN C-terminal domain 328 388 3.9E-11 T 12-10-2018 IPR010723 HemN, C-terminal MIM_c38160 e4777ccb5ede842932943a656f6f37d8 314 SUPERFAMILY SSF46785 1 82 1.1E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c38160 e4777ccb5ede842932943a656f6f37d8 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.9E-13 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c38160 e4777ccb5ede842932943a656f6f37d8 314 SUPERFAMILY SSF53850 91 290 3.06E-32 T 12-10-2018 MIM_c38160 e4777ccb5ede842932943a656f6f37d8 314 Gene3D G3DSA:1.10.10.10 1 92 1.5E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c38160 e4777ccb5ede842932943a656f6f37d8 314 Gene3D G3DSA:3.40.190.290 93 298 1.3E-31 T 12-10-2018 MIM_c38160 e4777ccb5ede842932943a656f6f37d8 314 Pfam PF03466 LysR substrate binding domain 90 288 6.8E-31 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c04440 722dac3d641b00b10a3fabce43acd0af 168 Gene3D G3DSA:1.10.10.10 79 165 2.9E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c04440 722dac3d641b00b10a3fabce43acd0af 168 SUPERFAMILY SSF88946 12 91 3.22E-9 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MIM_c04440 722dac3d641b00b10a3fabce43acd0af 168 Pfam PF04542 Sigma-70 region 2 16 75 2.8E-6 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MIM_c04440 722dac3d641b00b10a3fabce43acd0af 168 SUPERFAMILY SSF88659 90 165 1.68E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MIM_c04440 722dac3d641b00b10a3fabce43acd0af 168 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 162 3.4E-24 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MIM_c04440 722dac3d641b00b10a3fabce43acd0af 168 Pfam PF08281 Sigma-70, region 4 106 158 5.6E-13 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MIM_c28340 9d717bb65e3ac18a9165710d4922a77a 197 SUPERFAMILY SSF55811 28 195 1.62E-49 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MIM_c28340 9d717bb65e3ac18a9165710d4922a77a 197 Gene3D G3DSA:3.90.79.10 23 195 1.6E-54 T 12-10-2018 MIM_c28340 9d717bb65e3ac18a9165710d4922a77a 197 Pfam PF00293 NUDIX domain 63 181 2.5E-16 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MIM_c14820 b4c72c82897454ecd9888516ecba2896 265 Pfam PF02649 Type I GTP cyclohydrolase folE2 11 261 3.9E-86 T 12-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 MIM_c14820 b4c72c82897454ecd9888516ecba2896 265 Hamap MF_01527_B GTP cyclohydrolase FolE2 [folE2]. 11 265 33.361 T 12-10-2018 IPR022838 GTP cyclohydrolase FolE2 GO:0003934|GO:0035998 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 MIM_c14820 b4c72c82897454ecd9888516ecba2896 265 Gene3D G3DSA:3.10.270.10 9 264 1.7E-87 T 12-10-2018 MIM_c26670 ebaf7da45c82dd6bbcdfb6b1ecaf95d1 385 Gene3D G3DSA:3.40.50.10350 7 365 2.9E-136 T 12-10-2018 IPR018197 Glycerate kinase, restriction-enzyme-like fold MIM_c26670 ebaf7da45c82dd6bbcdfb6b1ecaf95d1 385 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 7 376 7.2E-137 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 MIM_c26670 ebaf7da45c82dd6bbcdfb6b1ecaf95d1 385 PIRSF PIRSF006078 5 380 5.2E-133 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 MIM_c26670 ebaf7da45c82dd6bbcdfb6b1ecaf95d1 385 Gene3D G3DSA:3.90.1510.10 46 279 2.9E-136 T 12-10-2018 IPR018193 Glycerate kinase, flavodoxin-like fold GO:0008887|GO:0031388 MIM_c26670 ebaf7da45c82dd6bbcdfb6b1ecaf95d1 385 SUPERFAMILY SSF110738 7 376 3.14E-125 T 12-10-2018 IPR036129 Glycerate kinase superfamily GO:0008887|GO:0031388 MIM_c26670 ebaf7da45c82dd6bbcdfb6b1ecaf95d1 385 Pfam PF02595 Glycerate kinase family 7 375 2.0E-138 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 MIM_c10400 0a239d815dca7485d4b57bd7d936016d 190 ProSitePatterns PS00893 Nudix box signature. 85 106 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MIM_c10400 0a239d815dca7485d4b57bd7d936016d 190 Pfam PF14803 Nudix N-terminal 18 49 7.0E-16 T 12-10-2018 IPR029401 Nudix hydrolase, N-terminal KEGG: 00230+3.6.1.13|KEGG: 00740+3.6.1.18 MIM_c10400 0a239d815dca7485d4b57bd7d936016d 190 SUPERFAMILY SSF55811 18 177 1.9E-39 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MIM_c10400 0a239d815dca7485d4b57bd7d936016d 190 Gene3D G3DSA:3.90.79.10 51 190 3.3E-36 T 12-10-2018 MIM_c10400 0a239d815dca7485d4b57bd7d936016d 190 Pfam PF00293 NUDIX domain 56 156 9.4E-14 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MIM_c10400 0a239d815dca7485d4b57bd7d936016d 190 Gene3D G3DSA:2.20.70.10 15 50 6.9E-15 T 12-10-2018 MIM_c27950 8228b25781256fd18db3d8a73640d418 116 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 24 107 2.9E-25 T 12-10-2018 IPR003849 Preprotein translocase YajC MIM_c27950 8228b25781256fd18db3d8a73640d418 116 Pfam PF02699 Preprotein translocase subunit 26 105 9.1E-30 T 12-10-2018 IPR003849 Preprotein translocase YajC MIM_c27950 8228b25781256fd18db3d8a73640d418 116 PRINTS PR01853 Bacterial YajC preprotein translocase signature 62 80 1.4E-17 T 12-10-2018 IPR003849 Preprotein translocase YajC MIM_c27950 8228b25781256fd18db3d8a73640d418 116 PRINTS PR01853 Bacterial YajC preprotein translocase signature 24 44 1.4E-17 T 12-10-2018 IPR003849 Preprotein translocase YajC MIM_c27950 8228b25781256fd18db3d8a73640d418 116 SMART SM01323 22 108 1.6E-42 T 12-10-2018 IPR003849 Preprotein translocase YajC MIM_c08710 0ddf15e78537036f90f35ea0bc3006ba 497 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 21 440 6.2E-141 T 12-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane MIM_c23610 3519721661724048a91b263a89389860 659 SUPERFAMILY SSF56801 19 655 3.79E-173 T 12-10-2018 MIM_c23610 3519721661724048a91b263a89389860 659 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 10 659 52.05 T 12-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 MIM_c23610 3519721661724048a91b263a89389860 659 Gene3D G3DSA:3.40.50.12780 61 527 4.3E-104 T 12-10-2018 MIM_c23610 3519721661724048a91b263a89389860 659 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 33 88 2.6E-22 T 12-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 MIM_c23610 3519721661724048a91b263a89389860 659 Pfam PF00501 AMP-binding enzyme 92 534 6.3E-90 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MIM_c23610 3519721661724048a91b263a89389860 659 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 29 657 3.4E-298 T 12-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 MIM_c23610 3519721661724048a91b263a89389860 659 Gene3D G3DSA:3.30.300.30 530 659 2.4E-29 T 12-10-2018 MIM_c23610 3519721661724048a91b263a89389860 659 ProSitePatterns PS00455 Putative AMP-binding domain signature. 268 279 - T 12-10-2018 IPR020845 AMP-binding, conserved site MIM_c23610 3519721661724048a91b263a89389860 659 Pfam PF13193 AMP-binding enzyme C-terminal domain 543 624 1.2E-27 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MIM_c04240 197ada45f846c30aeac127ecc5a14f44 273 SMART SM00382 41 230 2.4E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c04240 197ada45f846c30aeac127ecc5a14f44 273 SUPERFAMILY SSF52540 15 239 2.25E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c04240 197ada45f846c30aeac127ecc5a14f44 273 Gene3D G3DSA:3.40.50.300 14 271 1.2E-59 T 12-10-2018 MIM_c04240 197ada45f846c30aeac127ecc5a14f44 273 Pfam PF00005 ABC transporter 34 182 2.8E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c18260 f88761718ab9ad4bc3f1f8c2ac63fda1 764 SUPERFAMILY SSF51726 3 400 7.19E-107 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MIM_c18260 f88761718ab9ad4bc3f1f8c2ac63fda1 764 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 436 758 1.3E-155 T 12-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MIM_c18260 f88761718ab9ad4bc3f1f8c2ac63fda1 764 PIRSF PIRSF000382 1 764 0.0 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MIM_c18260 f88761718ab9ad4bc3f1f8c2ac63fda1 764 Gene3D G3DSA:3.20.20.210 395 761 0.0 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MIM_c18260 f88761718ab9ad4bc3f1f8c2ac63fda1 764 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 4 320 9.1E-117 T 12-10-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MIM_c18260 f88761718ab9ad4bc3f1f8c2ac63fda1 764 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 7 762 0.0 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MIM_c18260 f88761718ab9ad4bc3f1f8c2ac63fda1 764 Gene3D G3DSA:3.20.20.210 6 529 0.0 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MIM_c18260 f88761718ab9ad4bc3f1f8c2ac63fda1 764 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 2 763 36.778 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MIM_c18260 f88761718ab9ad4bc3f1f8c2ac63fda1 764 SUPERFAMILY SSF51726 413 761 1.83E-117 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MIM_c23910 40ab8830f3feb49e810f3fb31c9de962 248 SUPERFAMILY SSF51735 9 247 1.58E-81 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c23910 40ab8830f3feb49e810f3fb31c9de962 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c23910 40ab8830f3feb49e810f3fb31c9de962 248 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 12 245 5.1E-96 T 12-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MIM_c23910 40ab8830f3feb49e810f3fb31c9de962 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 219 8.9E-4 T 12-10-2018 MIM_c23910 40ab8830f3feb49e810f3fb31c9de962 248 Gene3D G3DSA:3.40.50.720 1 247 4.0E-83 T 12-10-2018 MIM_c23910 40ab8830f3feb49e810f3fb31c9de962 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 4.2E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c23910 40ab8830f3feb49e810f3fb31c9de962 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 4.2E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c23910 40ab8830f3feb49e810f3fb31c9de962 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 4.2E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c23910 40ab8830f3feb49e810f3fb31c9de962 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 4.2E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c23910 40ab8830f3feb49e810f3fb31c9de962 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 4.2E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c23910 40ab8830f3feb49e810f3fb31c9de962 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 4.2E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c23910 40ab8830f3feb49e810f3fb31c9de962 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 3.7E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c23910 40ab8830f3feb49e810f3fb31c9de962 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.7E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c23910 40ab8830f3feb49e810f3fb31c9de962 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.7E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c23910 40ab8830f3feb49e810f3fb31c9de962 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 245 6.3E-64 T 12-10-2018 MIM_c23070 7a6c25545f585a2866bbadbd1d330433 449 SUPERFAMILY SSF103473 37 435 4.84E-34 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c23070 7a6c25545f585a2866bbadbd1d330433 449 Gene3D G3DSA:1.20.1250.20 40 438 2.2E-30 T 12-10-2018 MIM_c23070 7a6c25545f585a2866bbadbd1d330433 449 Pfam PF07690 Major Facilitator Superfamily 38 332 8.5E-14 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c02080 c7cbf0016557c269ae9d1e7b9982ccdc 274 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 269 5.1E-37 T 12-10-2018 MIM_c02080 c7cbf0016557c269ae9d1e7b9982ccdc 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 157 4.2E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c02080 c7cbf0016557c269ae9d1e7b9982ccdc 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.2E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c02080 c7cbf0016557c269ae9d1e7b9982ccdc 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 233 253 4.2E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c02080 c7cbf0016557c269ae9d1e7b9982ccdc 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 4.2E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c02080 c7cbf0016557c269ae9d1e7b9982ccdc 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 4.2E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c02080 c7cbf0016557c269ae9d1e7b9982ccdc 274 Gene3D G3DSA:3.40.50.720 1 274 1.9E-58 T 12-10-2018 MIM_c02080 c7cbf0016557c269ae9d1e7b9982ccdc 274 SUPERFAMILY SSF51735 7 270 5.92E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c23390 e30998900da0b9ac518a39f79424d44a 151 SUPERFAMILY SSF54534 7 150 6.09E-23 T 12-10-2018 MIM_c23390 e30998900da0b9ac518a39f79424d44a 151 Gene3D G3DSA:3.10.50.40 25 148 1.8E-28 T 12-10-2018 MIM_c23390 e30998900da0b9ac518a39f79424d44a 151 Gene3D G3DSA:2.40.10.330 76 136 1.8E-28 T 12-10-2018 MIM_c14240 0a1acde660a93c53a79f58086ad6afb0 321 Gene3D G3DSA:1.20.1530.20 1 306 1.7E-109 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily MIM_c14240 0a1acde660a93c53a79f58086ad6afb0 321 Pfam PF01758 Sodium Bile acid symporter family 42 220 2.0E-42 T 12-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 MIM_c39830 56de2c4177252e75e5b2c28669ee05eb 310 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 11 305 4.0E-31 T 12-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 MIM_c39830 56de2c4177252e75e5b2c28669ee05eb 310 Gene3D G3DSA:3.30.1780.10 27 303 3.4E-59 T 12-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 MIM_c39830 56de2c4177252e75e5b2c28669ee05eb 310 SUPERFAMILY SSF51735 5 308 6.16E-62 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c39830 56de2c4177252e75e5b2c28669ee05eb 310 Gene3D G3DSA:3.40.50.720 128 292 3.4E-59 T 12-10-2018 MIM_c39830 56de2c4177252e75e5b2c28669ee05eb 310 PIRSF PIRSF001439 2 309 2.2E-45 T 12-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 MIM_c06370 f0fdd52f27bccfe302f03fa104f878ca 336 PRINTS PR00069 Aldo-keto reductase signature 134 151 5.9E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MIM_c06370 f0fdd52f27bccfe302f03fa104f878ca 336 PRINTS PR00069 Aldo-keto reductase signature 103 121 5.9E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MIM_c06370 f0fdd52f27bccfe302f03fa104f878ca 336 PRINTS PR00069 Aldo-keto reductase signature 39 63 5.9E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MIM_c06370 f0fdd52f27bccfe302f03fa104f878ca 336 SUPERFAMILY SSF51430 1 312 6.42E-95 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MIM_c06370 f0fdd52f27bccfe302f03fa104f878ca 336 Gene3D G3DSA:3.20.20.100 1 322 4.9E-107 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MIM_c06370 f0fdd52f27bccfe302f03fa104f878ca 336 Pfam PF00248 Aldo/keto reductase family 15 310 4.2E-69 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain MIM_c19160 9858b62d37ad946393dc10a021a1ce86 718 Gene3D G3DSA:1.10.1370.10 153 640 2.1E-238 T 12-10-2018 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 MIM_c19160 9858b62d37ad946393dc10a021a1ce86 718 Pfam PF01432 Peptidase family M3 257 712 1.8E-127 T 12-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 MIM_c19160 9858b62d37ad946393dc10a021a1ce86 718 SUPERFAMILY SSF55486 15 712 8.67E-182 T 12-10-2018 MIM_c19160 9858b62d37ad946393dc10a021a1ce86 718 Gene3D G3DSA:1.10.1370.40 26 710 2.1E-238 T 12-10-2018 MIM_c02670 0d0d9ec05e78bd47d173074ea4060e05 334 Gene3D G3DSA:3.40.190.10 37 322 1.4E-47 T 12-10-2018 MIM_c02670 0d0d9ec05e78bd47d173074ea4060e05 334 SUPERFAMILY SSF53850 30 329 2.17E-77 T 12-10-2018 MIM_c02670 0d0d9ec05e78bd47d173074ea4060e05 334 Gene3D G3DSA:3.40.190.100 120 248 1.4E-47 T 12-10-2018 MIM_c02670 0d0d9ec05e78bd47d173074ea4060e05 334 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 35 313 5.4E-60 T 12-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 MIM_c01550 7f4fe88cef8a3103821fa54fd3761982 362 Gene3D G3DSA:3.20.20.30 1 362 1.7E-120 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MIM_c01550 7f4fe88cef8a3103821fa54fd3761982 362 Pfam PF00296 Luciferase-like monooxygenase 4 337 2.2E-78 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MIM_c01550 7f4fe88cef8a3103821fa54fd3761982 362 SUPERFAMILY SSF51679 3 361 1.83E-79 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MIM_c30730 be8266a175c727cfb5dbb0513ae03528 247 Gene3D G3DSA:3.40.225.10 1 247 3.7E-74 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily MIM_c30730 be8266a175c727cfb5dbb0513ae03528 247 SUPERFAMILY SSF53639 6 216 5.3E-58 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily MIM_c30730 be8266a175c727cfb5dbb0513ae03528 247 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 13 194 9.8E-44 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal MIM_c30730 be8266a175c727cfb5dbb0513ae03528 247 SMART SM01007 12 194 1.4E-59 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal MIM_c35300 37b719ee3aa9f74c06ecf4475b2c79a3 196 Pfam PF13875 Domain of unknown function (DUF4202) 9 187 4.0E-63 T 12-10-2018 IPR025255 Protein of unknown function DUF4202 MIM_c35730 f8f40412156e4e65aa2465d7240323d6 279 SUPERFAMILY SSF52172 7 127 2.28E-24 T 12-10-2018 IPR011006 CheY-like superfamily MIM_c35730 f8f40412156e4e65aa2465d7240323d6 279 SMART SM00862 195 272 7.9E-16 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MIM_c35730 f8f40412156e4e65aa2465d7240323d6 279 Gene3D G3DSA:3.40.50.2300 2 126 3.0E-25 T 12-10-2018 MIM_c35730 f8f40412156e4e65aa2465d7240323d6 279 Gene3D G3DSA:1.10.10.10 164 278 5.0E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c35730 f8f40412156e4e65aa2465d7240323d6 279 Pfam PF00486 Transcriptional regulatory protein, C terminal 196 272 2.2E-16 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MIM_c35730 f8f40412156e4e65aa2465d7240323d6 279 SMART SM00448 9 117 8.0E-17 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c35730 f8f40412156e4e65aa2465d7240323d6 279 SUPERFAMILY SSF46894 173 273 3.97E-19 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MIM_c35730 f8f40412156e4e65aa2465d7240323d6 279 Pfam PF00072 Response regulator receiver domain 11 115 5.6E-13 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c07160 f02c7aafd0460800a895dd98e06865bc 172 SUPERFAMILY SSF46785 28 161 5.47E-29 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c07160 f02c7aafd0460800a895dd98e06865bc 172 Gene3D G3DSA:1.10.10.10 22 163 2.6E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c07160 f02c7aafd0460800a895dd98e06865bc 172 SMART SM00347 48 149 1.0E-17 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c07160 f02c7aafd0460800a895dd98e06865bc 172 Pfam PF01047 MarR family 55 112 4.3E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c07160 f02c7aafd0460800a895dd98e06865bc 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 109 125 2.0E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c07160 f02c7aafd0460800a895dd98e06865bc 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 105 2.0E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c07160 f02c7aafd0460800a895dd98e06865bc 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 73 89 2.0E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c07160 f02c7aafd0460800a895dd98e06865bc 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 139 159 2.0E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c13980 1328957f514471d3f366ea56da908de4 489 Pfam PF03972 MmgE/PrpD family 32 452 7.9E-114 T 12-10-2018 IPR005656 MmgE/PrpD GO:0016829 MIM_c13980 1328957f514471d3f366ea56da908de4 489 SUPERFAMILY SSF103378 29 479 6.67E-107 T 12-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 MIM_c13980 1328957f514471d3f366ea56da908de4 489 Gene3D G3DSA:1.10.4100.10 49 449 4.7E-109 T 12-10-2018 MIM_c13980 1328957f514471d3f366ea56da908de4 489 Gene3D G3DSA:3.30.1330.120 294 431 4.7E-109 T 12-10-2018 MIM_c35760 ead637302f9214d5692474813e2f4e9c 302 Gene3D G3DSA:1.10.10.10 4 88 5.4E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c35760 ead637302f9214d5692474813e2f4e9c 302 Gene3D G3DSA:3.40.190.10 93 295 1.1E-53 T 12-10-2018 MIM_c35760 ead637302f9214d5692474813e2f4e9c 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 3.5E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c35760 ead637302f9214d5692474813e2f4e9c 302 SUPERFAMILY SSF46785 3 112 3.3E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c35760 ead637302f9214d5692474813e2f4e9c 302 SUPERFAMILY SSF53850 90 297 5.89E-36 T 12-10-2018 MIM_c35760 ead637302f9214d5692474813e2f4e9c 302 Gene3D G3DSA:3.40.190.10 166 271 1.1E-53 T 12-10-2018 MIM_c35760 ead637302f9214d5692474813e2f4e9c 302 Pfam PF03466 LysR substrate binding domain 89 297 9.2E-33 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c32890 d7341517cd6c2ad84c3afdd47635ec9e 299 SMART SM00481 16 83 0.0018 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal MIM_c32890 d7341517cd6c2ad84c3afdd47635ec9e 299 Gene3D G3DSA:3.20.20.140 8 229 8.8E-33 T 12-10-2018 MIM_c32890 d7341517cd6c2ad84c3afdd47635ec9e 299 SUPERFAMILY SSF89550 13 225 2.09E-31 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MIM_c34160 f1c3c50fd186e4fb0f2e42cebff7945c 220 Pfam PF00857 Isochorismatase family 13 203 1.5E-42 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 MIM_c34160 f1c3c50fd186e4fb0f2e42cebff7945c 220 Gene3D G3DSA:3.40.50.850 8 217 1.2E-66 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MIM_c34160 f1c3c50fd186e4fb0f2e42cebff7945c 220 SUPERFAMILY SSF52499 8 207 3.79E-59 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MIM_c09380 e8e8796e0534a6ea807fd5160ef16609 666 PRINTS PR00415 Aconitase family signature 432 445 1.2E-19 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c09380 e8e8796e0534a6ea807fd5160ef16609 666 PRINTS PR00415 Aconitase family signature 418 431 1.2E-19 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c09380 e8e8796e0534a6ea807fd5160ef16609 666 PRINTS PR00415 Aconitase family signature 354 369 1.2E-19 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c09380 e8e8796e0534a6ea807fd5160ef16609 666 PRINTS PR00415 Aconitase family signature 528 539 1.2E-19 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c09380 e8e8796e0534a6ea807fd5160ef16609 666 PRINTS PR00415 Aconitase family signature 589 602 1.2E-19 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c09380 e8e8796e0534a6ea807fd5160ef16609 666 PRINTS PR00415 Aconitase family signature 340 353 1.2E-19 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c09380 e8e8796e0534a6ea807fd5160ef16609 666 SUPERFAMILY SSF52016 42 185 1.69E-24 T 12-10-2018 MIM_c09380 e8e8796e0534a6ea807fd5160ef16609 666 Gene3D G3DSA:3.20.19.10 37 195 6.9E-28 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 MIM_c09380 e8e8796e0534a6ea807fd5160ef16609 666 Gene3D G3DSA:3.30.499.10 504 664 4.7E-37 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 MIM_c09380 e8e8796e0534a6ea807fd5160ef16609 666 SUPERFAMILY SSF53732 182 656 1.83E-102 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 MIM_c09380 e8e8796e0534a6ea807fd5160ef16609 666 Pfam PF00330 Aconitase family (aconitate hydratase) 327 647 7.9E-82 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MIM_c09380 e8e8796e0534a6ea807fd5160ef16609 666 Gene3D G3DSA:3.30.499.20 203 501 8.2E-72 T 12-10-2018 MIM_c09380 e8e8796e0534a6ea807fd5160ef16609 666 Pfam PF00694 Aconitase C-terminal domain 84 141 8.1E-15 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 MIM_c04560 5dba13cb9ebe22be2a493b50abceb4aa 291 SUPERFAMILY SSF81452 12 290 1.47E-78 T 12-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c04560 5dba13cb9ebe22be2a493b50abceb4aa 291 Gene3D G3DSA:1.10.287.70 7 78 2.4E-14 T 12-10-2018 MIM_c04560 5dba13cb9ebe22be2a493b50abceb4aa 291 Gene3D G3DSA:1.20.120.80 79 291 1.8E-65 T 12-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c04560 5dba13cb9ebe22be2a493b50abceb4aa 291 Pfam PF00510 Cytochrome c oxidase subunit III 16 291 5.2E-58 T 12-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c30970 9e56d3ec0ab2c65b1f8c45af525b9ffb 453 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 150 397 1.8E-25 T 12-10-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 MIM_c30970 9e56d3ec0ab2c65b1f8c45af525b9ffb 453 SUPERFAMILY SSF51735 2 201 2.94E-18 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c30970 9e56d3ec0ab2c65b1f8c45af525b9ffb 453 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 5 146 1.9E-31 T 12-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 MIM_c30970 9e56d3ec0ab2c65b1f8c45af525b9ffb 453 Gene3D G3DSA:3.30.360.10 160 356 1.5E-134 T 12-10-2018 MIM_c30970 9e56d3ec0ab2c65b1f8c45af525b9ffb 453 Gene3D G3DSA:3.40.50.720 6 397 1.5E-134 T 12-10-2018 MIM_c16470 4d2bba280a72c7a9549f04b66dabd9be 446 Gene3D G3DSA:1.20.1250.20 242 440 4.9E-21 T 12-10-2018 MIM_c16470 4d2bba280a72c7a9549f04b66dabd9be 446 Pfam PF07690 Major Facilitator Superfamily 39 284 9.0E-30 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c16470 4d2bba280a72c7a9549f04b66dabd9be 446 Gene3D G3DSA:1.20.1250.20 16 208 1.9E-27 T 12-10-2018 MIM_c16470 4d2bba280a72c7a9549f04b66dabd9be 446 SUPERFAMILY SSF103473 16 434 4.84E-60 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c24510 fad1d98e79912e165a88c0df29460f6b 162 Gene3D G3DSA:3.30.70.3270 36 162 1.8E-37 T 12-10-2018 MIM_c24510 fad1d98e79912e165a88c0df29460f6b 162 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 19 140 6.3E-47 T 12-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24510 fad1d98e79912e165a88c0df29460f6b 162 Pfam PF12838 4Fe-4S dicluster domain 62 115 4.1E-12 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MIM_c24510 fad1d98e79912e165a88c0df29460f6b 162 SUPERFAMILY SSF54862 36 145 1.51E-24 T 12-10-2018 MIM_c24510 fad1d98e79912e165a88c0df29460f6b 162 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 63 74 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MIM_c24510 fad1d98e79912e165a88c0df29460f6b 162 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 102 113 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MIM_c24510 fad1d98e79912e165a88c0df29460f6b 162 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 10 159 28.262 T 12-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c04400 c560a166b0ea57c6ba165c8c92c64296 478 SUPERFAMILY SSF103378 16 465 3.79E-102 T 12-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 MIM_c04400 c560a166b0ea57c6ba165c8c92c64296 478 Gene3D G3DSA:1.10.4100.10 38 435 3.5E-92 T 12-10-2018 MIM_c04400 c560a166b0ea57c6ba165c8c92c64296 478 Gene3D G3DSA:3.30.1330.120 285 419 3.5E-92 T 12-10-2018 MIM_c04400 c560a166b0ea57c6ba165c8c92c64296 478 Pfam PF03972 MmgE/PrpD family 20 458 9.7E-117 T 12-10-2018 IPR005656 MmgE/PrpD GO:0016829 MIM_c26520 c716fdb8bb497145ae414ab5bc3bb815 493 Pfam PF00501 AMP-binding enzyme 19 393 5.9E-77 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MIM_c26520 c716fdb8bb497145ae414ab5bc3bb815 493 Pfam PF13193 AMP-binding enzyme C-terminal domain 403 477 1.9E-15 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MIM_c26520 c716fdb8bb497145ae414ab5bc3bb815 493 SUPERFAMILY SSF56801 20 489 1.31E-125 T 12-10-2018 MIM_c26520 c716fdb8bb497145ae414ab5bc3bb815 493 Gene3D G3DSA:3.30.300.30 390 490 8.9E-28 T 12-10-2018 MIM_c26520 c716fdb8bb497145ae414ab5bc3bb815 493 ProSitePatterns PS00455 Putative AMP-binding domain signature. 149 160 - T 12-10-2018 IPR020845 AMP-binding, conserved site MIM_c26520 c716fdb8bb497145ae414ab5bc3bb815 493 Gene3D G3DSA:3.40.50.12780 13 389 3.0E-88 T 12-10-2018 MIM_c27380 efcb33117ab13270aba6aa2e54dffca7 388 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 230 357 2.1E-6 T 12-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 MIM_c27380 efcb33117ab13270aba6aa2e54dffca7 388 SUPERFAMILY SSF53756 86 350 1.64E-17 T 12-10-2018 MIM_c27380 efcb33117ab13270aba6aa2e54dffca7 388 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 16 179 4.0E-6 T 12-10-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 MIM_c27380 efcb33117ab13270aba6aa2e54dffca7 388 Gene3D G3DSA:3.40.50.2000 198 356 4.3E-22 T 12-10-2018 MIM_c07070 147721c642e1d0ab9dd808d59889d135 432 Pfam PF00501 AMP-binding enzyme 147 296 4.1E-14 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MIM_c07070 147721c642e1d0ab9dd808d59889d135 432 Gene3D G3DSA:3.30.300.30 336 430 4.1E-13 T 12-10-2018 MIM_c07070 147721c642e1d0ab9dd808d59889d135 432 SUPERFAMILY SSF56801 136 423 3.4E-33 T 12-10-2018 MIM_c07070 147721c642e1d0ab9dd808d59889d135 432 Gene3D G3DSA:3.40.50.12780 1 335 5.4E-55 T 12-10-2018 MIM_c06010 81967731b7c3b4f22d3740e6e25ca4c9 326 SUPERFAMILY SSF53850 112 287 6.52E-13 T 12-10-2018 MIM_c06010 81967731b7c3b4f22d3740e6e25ca4c9 326 PIRSF PIRSF017082 5 325 5.3E-74 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c06010 81967731b7c3b4f22d3740e6e25ca4c9 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 321 2.1E-68 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c06010 81967731b7c3b4f22d3740e6e25ca4c9 326 Gene3D G3DSA:3.40.190.10 127 250 9.2E-98 T 12-10-2018 MIM_c06010 81967731b7c3b4f22d3740e6e25ca4c9 326 Gene3D G3DSA:3.40.190.150 32 315 9.2E-98 T 12-10-2018 MIM_c11600 b3605a4da0a7d7b0f82734a6c3e968ef 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 26 218 7.0E-25 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c11600 b3605a4da0a7d7b0f82734a6c3e968ef 223 SUPERFAMILY SSF161098 4 215 1.57E-52 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c11600 b3605a4da0a7d7b0f82734a6c3e968ef 223 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 10 216 2.9E-76 T 12-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 MIM_c11600 b3605a4da0a7d7b0f82734a6c3e968ef 223 Gene3D G3DSA:1.10.3720.10 2 220 9.7E-62 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c28940 429ede4fe9b07ef3b0ae5dec8cf5dd2d 142 Pfam PF11162 Protein of unknown function (DUF2946) 19 138 2.2E-6 T 12-10-2018 IPR021333 Protein of unknown function DUF2946 MIM_c30800 b4b7a58518f7291c43dd00793afd9fca 311 Gene3D G3DSA:1.10.10.10 1 88 6.4E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c30800 b4b7a58518f7291c43dd00793afd9fca 311 Gene3D G3DSA:3.40.190.290 91 298 8.0E-40 T 12-10-2018 MIM_c30800 b4b7a58518f7291c43dd00793afd9fca 311 SUPERFAMILY SSF53850 89 295 1.1E-39 T 12-10-2018 MIM_c30800 b4b7a58518f7291c43dd00793afd9fca 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c30800 b4b7a58518f7291c43dd00793afd9fca 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c30800 b4b7a58518f7291c43dd00793afd9fca 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c30800 b4b7a58518f7291c43dd00793afd9fca 311 SUPERFAMILY SSF46785 1 85 1.22E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c30800 b4b7a58518f7291c43dd00793afd9fca 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 3.8E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c30800 b4b7a58518f7291c43dd00793afd9fca 311 Pfam PF03466 LysR substrate binding domain 87 290 8.8E-40 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c39430 33dee36d96c3af5a9686e769072865ef 339 Gene3D G3DSA:3.40.190.170 29 339 8.9E-104 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily MIM_c39430 33dee36d96c3af5a9686e769072865ef 339 PIRSF PIRSF006470 2 335 3.0E-110 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 MIM_c39430 33dee36d96c3af5a9686e769072865ef 339 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 36 290 1.1E-82 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 MIM_c39430 33dee36d96c3af5a9686e769072865ef 339 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 36 317 1.5E-92 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 MIM_c31650 a5cc6802091be336ba4ebf3e5b8e8de1 237 Gene3D G3DSA:3.40.50.12500 8 236 7.6E-58 T 12-10-2018 MIM_c31650 a5cc6802091be336ba4ebf3e5b8e8de1 237 SUPERFAMILY SSF53822 75 204 1.04E-6 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c31650 a5cc6802091be336ba4ebf3e5b8e8de1 237 PIRSF PIRSF015736 1 237 3.6E-51 T 12-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase MIM_c31650 a5cc6802091be336ba4ebf3e5b8e8de1 237 Pfam PF01177 Asp/Glu/Hydantoin racemase 48 215 3.4E-11 T 12-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MIM_c13060 783c9b063d914b14f03bb62750d12000 382 Pfam PF01266 FAD dependent oxidoreductase 8 354 3.2E-49 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MIM_c13060 783c9b063d914b14f03bb62750d12000 382 Gene3D G3DSA:3.30.9.10 89 314 4.0E-112 T 12-10-2018 MIM_c13060 783c9b063d914b14f03bb62750d12000 382 Gene3D G3DSA:3.50.50.60 8 354 4.0E-112 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c13060 783c9b063d914b14f03bb62750d12000 382 SUPERFAMILY SSF51905 7 365 4.32E-41 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c30000 d27fffc70930f896276078ec23b0135e 226 SUPERFAMILY SSF48452 107 217 3.29E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MIM_c30000 d27fffc70930f896276078ec23b0135e 226 Hamap MF_02066 Cell division coordinator CpoB [cpoB]. 5 225 17.569 T 12-10-2018 IPR034706 Cell division coordinator CpoB GO:0051301 MIM_c30000 d27fffc70930f896276078ec23b0135e 226 Pfam PF13432 Tetratricopeptide repeat 109 175 1.8E-9 T 12-10-2018 MIM_c30000 d27fffc70930f896276078ec23b0135e 226 Pfam PF13174 Tetratricopeptide repeat 180 212 1.1E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MIM_c30000 d27fffc70930f896276078ec23b0135e 226 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 104 222 3.4E-33 T 12-10-2018 IPR014162 Cell division coordinator CpoB, C-terminal MIM_c30000 d27fffc70930f896276078ec23b0135e 226 Gene3D G3DSA:1.25.40.10 105 226 1.8E-24 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MIM_c33210 16e05158264c95ce33c1e4d4f7521f39 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 2.4E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c33210 16e05158264c95ce33c1e4d4f7521f39 312 SUPERFAMILY SSF46785 6 86 9.8E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c33210 16e05158264c95ce33c1e4d4f7521f39 312 Gene3D G3DSA:3.40.190.10 99 275 2.3E-21 T 12-10-2018 MIM_c33210 16e05158264c95ce33c1e4d4f7521f39 312 Gene3D G3DSA:3.40.190.10 169 271 2.3E-21 T 12-10-2018 MIM_c33210 16e05158264c95ce33c1e4d4f7521f39 312 SUPERFAMILY SSF53850 98 301 5.97E-22 T 12-10-2018 MIM_c33210 16e05158264c95ce33c1e4d4f7521f39 312 Gene3D G3DSA:1.10.10.10 7 97 8.5E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c33210 16e05158264c95ce33c1e4d4f7521f39 312 Pfam PF03466 LysR substrate binding domain 96 297 1.4E-21 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c33210 16e05158264c95ce33c1e4d4f7521f39 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 1.3E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c33210 16e05158264c95ce33c1e4d4f7521f39 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 1.3E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c33210 16e05158264c95ce33c1e4d4f7521f39 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 1.3E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c24650 4347a281ce97e1e1d6afe12e1751833c 186 Pfam PF03840 Preprotein translocase SecG subunit 8 77 3.6E-20 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MIM_c24650 4347a281ce97e1e1d6afe12e1751833c 186 PRINTS PR01651 Protein-export SecG membrane protein signature 42 58 7.0E-29 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MIM_c24650 4347a281ce97e1e1d6afe12e1751833c 186 PRINTS PR01651 Protein-export SecG membrane protein signature 27 41 7.0E-29 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MIM_c24650 4347a281ce97e1e1d6afe12e1751833c 186 PRINTS PR01651 Protein-export SecG membrane protein signature 58 80 7.0E-29 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MIM_c24650 4347a281ce97e1e1d6afe12e1751833c 186 PRINTS PR01651 Protein-export SecG membrane protein signature 7 27 7.0E-29 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MIM_c24650 4347a281ce97e1e1d6afe12e1751833c 186 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 8 77 5.7E-24 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MIM_c21590 520ac4600400b66cc35aef5b4aab3e45 145 Gene3D G3DSA:3.40.630.30 1 145 2.2E-35 T 12-10-2018 MIM_c21590 520ac4600400b66cc35aef5b4aab3e45 145 SUPERFAMILY SSF55729 2 143 1.49E-23 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c21590 520ac4600400b66cc35aef5b4aab3e45 145 Pfam PF13673 Acetyltransferase (GNAT) domain 52 135 3.0E-15 T 12-10-2018 IPR000182 GNAT domain MIM_c25260 56494ff7f7949272b2e3d3052803a4cb 304 Gene3D G3DSA:3.40.190.290 91 293 2.0E-43 T 12-10-2018 MIM_c25260 56494ff7f7949272b2e3d3052803a4cb 304 SUPERFAMILY SSF53850 90 292 3.55E-34 T 12-10-2018 MIM_c25260 56494ff7f7949272b2e3d3052803a4cb 304 Gene3D G3DSA:1.10.10.10 1 90 3.8E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c25260 56494ff7f7949272b2e3d3052803a4cb 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.0E-23 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c25260 56494ff7f7949272b2e3d3052803a4cb 304 SUPERFAMILY SSF46785 1 86 3.85E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c25260 56494ff7f7949272b2e3d3052803a4cb 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.3E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c25260 56494ff7f7949272b2e3d3052803a4cb 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.3E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c25260 56494ff7f7949272b2e3d3052803a4cb 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.3E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c25260 56494ff7f7949272b2e3d3052803a4cb 304 Pfam PF03466 LysR substrate binding domain 89 290 5.1E-38 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c09830 3d9c975e8366c9f1b47407152563dc41 167 Pfam PF05258 Protein of unknown function (DUF721) 33 106 2.1E-6 T 12-10-2018 IPR007922 Protein of unknown function DUF721/UPF0232 MIM_c04710 2ac816c7f3938da465acfcd144b9dbe2 494 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 360 380 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MIM_c04710 2ac816c7f3938da465acfcd144b9dbe2 494 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 258 447 4.3E-60 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 MIM_c04710 2ac816c7f3938da465acfcd144b9dbe2 494 SUPERFAMILY SSF53067 3 252 5.33E-95 T 12-10-2018 MIM_c04710 2ac816c7f3938da465acfcd144b9dbe2 494 Gene3D G3DSA:3.30.420.40 1 250 2.9E-105 T 12-10-2018 MIM_c04710 2ac816c7f3938da465acfcd144b9dbe2 494 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 133 145 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MIM_c04710 2ac816c7f3938da465acfcd144b9dbe2 494 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 3 490 4.3E-209 T 12-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 MIM_c04710 2ac816c7f3938da465acfcd144b9dbe2 494 Hamap MF_00186 Glycerol kinase [glpK]. 1 494 54.7 T 12-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 MIM_c04710 2ac816c7f3938da465acfcd144b9dbe2 494 PIRSF PIRSF000538 1 492 1.1E-173 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MIM_c04710 2ac816c7f3938da465acfcd144b9dbe2 494 Gene3D G3DSA:3.30.420.40 251 492 4.6E-83 T 12-10-2018 MIM_c04710 2ac816c7f3938da465acfcd144b9dbe2 494 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 249 2.9E-76 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 MIM_c04710 2ac816c7f3938da465acfcd144b9dbe2 494 SUPERFAMILY SSF53067 252 492 1.55E-78 T 12-10-2018 MIM_c06440 b505888fa18ffb234cf5af44097eb2aa 315 SUPERFAMILY SSF53850 95 303 6.52E-25 T 12-10-2018 MIM_c06440 b505888fa18ffb234cf5af44097eb2aa 315 Gene3D G3DSA:3.40.190.10 102 294 5.8E-37 T 12-10-2018 MIM_c06440 b505888fa18ffb234cf5af44097eb2aa 315 Gene3D G3DSA:1.10.10.10 9 97 6.9E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c06440 b505888fa18ffb234cf5af44097eb2aa 315 Pfam PF03466 LysR substrate binding domain 95 298 2.5E-20 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c06440 b505888fa18ffb234cf5af44097eb2aa 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 69 1.6E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c06440 b505888fa18ffb234cf5af44097eb2aa 315 Gene3D G3DSA:3.40.190.10 162 267 5.8E-37 T 12-10-2018 MIM_c06440 b505888fa18ffb234cf5af44097eb2aa 315 SUPERFAMILY SSF46785 7 86 6.31E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c09580 186c9a569277731370b467450bf71bbf 409 Gene3D G3DSA:1.20.1250.20 9 210 8.0E-60 T 12-10-2018 MIM_c09580 186c9a569277731370b467450bf71bbf 409 SUPERFAMILY SSF103473 11 404 5.62E-39 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c09580 186c9a569277731370b467450bf71bbf 409 TIGRFAM TIGR00885 fucP: L-fucose:H+ symporter permease 13 398 2.6E-88 T 12-10-2018 IPR005275 L-fucose permease FucP GO:0015150|GO:0015756 MIM_c09580 186c9a569277731370b467450bf71bbf 409 Pfam PF07690 Major Facilitator Superfamily 20 366 3.9E-21 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c09580 186c9a569277731370b467450bf71bbf 409 Gene3D G3DSA:1.20.1250.20 216 403 4.7E-48 T 12-10-2018 MIM_c03450 67d5906ba11c3954ab6d724b56a4a5b9 254 SUPERFAMILY SSF52096 2 254 1.9E-72 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c03450 67d5906ba11c3954ab6d724b56a4a5b9 254 Gene3D G3DSA:1.10.12.10 200 254 1.2E-17 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MIM_c03450 67d5906ba11c3954ab6d724b56a4a5b9 254 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 253 2.2E-49 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c03450 67d5906ba11c3954ab6d724b56a4a5b9 254 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 MIM_c03450 67d5906ba11c3954ab6d724b56a4a5b9 254 Gene3D G3DSA:3.90.226.10 1 196 9.6E-56 T 12-10-2018 MIM_c19100 2948cf16915ccce8181eb1f0b55f74a2 308 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 292 9.5E-51 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c05810 c2806d9145641c1b55437f33ebcd2097 270 SUPERFAMILY SSF53613 5 269 8.42E-72 T 12-10-2018 IPR029056 Ribokinase-like MIM_c05810 c2806d9145641c1b55437f33ebcd2097 270 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 265 5.4E-88 T 12-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MIM_c05810 c2806d9145641c1b55437f33ebcd2097 270 Gene3D G3DSA:3.40.1190.20 2 269 1.4E-94 T 12-10-2018 IPR029056 Ribokinase-like MIM_c05810 c2806d9145641c1b55437f33ebcd2097 270 Pfam PF08543 Phosphomethylpyrimidine kinase 12 263 4.9E-86 T 12-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 MIM_c17260 0c4f7d9b81f4bd012c6a971793927ea0 86 Gene3D G3DSA:2.40.50.140 1 71 9.5E-32 T 12-10-2018 MIM_c17260 0c4f7d9b81f4bd012c6a971793927ea0 86 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 75 26.139 T 12-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 MIM_c17260 0c4f7d9b81f4bd012c6a971793927ea0 86 Pfam PF01176 Translation initiation factor 1A / IF-1 8 70 1.2E-23 T 12-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 MIM_c17260 0c4f7d9b81f4bd012c6a971793927ea0 86 SUPERFAMILY SSF50249 1 71 2.17E-25 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c17260 0c4f7d9b81f4bd012c6a971793927ea0 86 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 2.1E-31 T 12-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 MIM_c28280 47b2892188238fb27362c5667f2534e2 282 SUPERFAMILY SSF53613 8 267 2.16E-63 T 12-10-2018 IPR029056 Ribokinase-like MIM_c28280 47b2892188238fb27362c5667f2534e2 282 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 13 266 1.3E-57 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 MIM_c28280 47b2892188238fb27362c5667f2534e2 282 Gene3D G3DSA:3.40.1190.20 4 275 6.3E-72 T 12-10-2018 IPR029056 Ribokinase-like MIM_c28280 47b2892188238fb27362c5667f2534e2 282 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 6 275 19.782 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 MIM_c28280 47b2892188238fb27362c5667f2534e2 282 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 213 223 - T 12-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site MIM_c28280 47b2892188238fb27362c5667f2534e2 282 Pfam PF01256 Carbohydrate kinase 29 255 1.1E-48 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 MIM_c17090 55bbd3876459d9233d6ce62f6d9f25d6 408 Gene3D G3DSA:1.20.1250.20 12 387 2.2E-39 T 12-10-2018 MIM_c17090 55bbd3876459d9233d6ce62f6d9f25d6 408 Pfam PF07690 Major Facilitator Superfamily 25 326 6.4E-26 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c17090 55bbd3876459d9233d6ce62f6d9f25d6 408 SUPERFAMILY SSF103473 5 391 1.44E-49 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c19590 ad9cb54999569d45403158d44abbecd4 337 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 7 334 32.637 T 12-10-2018 IPR003770 Endolytic murein transglycosylase MIM_c19590 ad9cb54999569d45403158d44abbecd4 337 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 7 333 3.1E-84 T 12-10-2018 IPR003770 Endolytic murein transglycosylase MIM_c19590 ad9cb54999569d45403158d44abbecd4 337 Pfam PF02618 YceG-like family 44 328 1.0E-79 T 12-10-2018 IPR003770 Endolytic murein transglycosylase MIM_c19590 ad9cb54999569d45403158d44abbecd4 337 Gene3D G3DSA:3.30.160.60 302 336 4.1E-8 T 12-10-2018 MIM_c19590 ad9cb54999569d45403158d44abbecd4 337 Gene3D G3DSA:1.10.8.1150 38 112 3.8E-8 T 12-10-2018 MIM_c35520 21ea08e336fbe28f6c61683523b4e86c 294 Pfam PF02567 Phenazine biosynthesis-like protein 9 268 1.4E-18 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MIM_c35520 21ea08e336fbe28f6c61683523b4e86c 294 Gene3D G3DSA:3.10.310.10 6 126 7.5E-17 T 12-10-2018 MIM_c35520 21ea08e336fbe28f6c61683523b4e86c 294 Gene3D G3DSA:3.10.310.10 127 276 4.4E-15 T 12-10-2018 MIM_c35520 21ea08e336fbe28f6c61683523b4e86c 294 PIRSF PIRSF016184 7 282 1.9E-26 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MIM_c35520 21ea08e336fbe28f6c61683523b4e86c 294 SUPERFAMILY SSF54506 9 279 3.81E-29 T 12-10-2018 MIM_c12930 aa36ebf7a6bd0e5fdfd0f283b4b2849a 343 Pfam PF01610 Transposase 151 342 2.7E-39 T 12-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain MIM_c12930 aa36ebf7a6bd0e5fdfd0f283b4b2849a 343 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 33 78 1.2E-5 T 12-10-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger MIM_c40870 3bcf61a30136d432766f4e44f09b7225 288 SUPERFAMILY SSF53474 23 265 1.28E-20 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c40870 3bcf61a30136d432766f4e44f09b7225 288 Gene3D G3DSA:3.40.50.1820 18 282 9.6E-53 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c25170 daa4443e3e6ae9049aa59b36c90132fe 162 SMART SM00347 40 140 5.8E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c25170 daa4443e3e6ae9049aa59b36c90132fe 162 SUPERFAMILY SSF46785 41 155 3.29E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c25170 daa4443e3e6ae9049aa59b36c90132fe 162 Pfam PF01047 MarR family 50 104 7.0E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c25170 daa4443e3e6ae9049aa59b36c90132fe 162 Gene3D G3DSA:1.10.10.10 8 157 1.0E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c26240 a35cf4f9999b550465f4a0e759e98359 67 TIGRFAM TIGR02683 upstrm_HI1419: putative addiction module killer protein 3 58 9.5E-27 T 12-10-2018 IPR014056 Addiction module killer protein, predicted MIM_c26240 a35cf4f9999b550465f4a0e759e98359 67 PIRSF PIRSF028744 1 63 3.5E-27 T 12-10-2018 IPR014056 Addiction module killer protein, predicted MIM_c06110 0665b8589c810621950fa99e918add85 412 PIRSF PIRSF007313 1 396 1.3E-152 T 12-10-2018 IPR008773 Phosphonate metabolism protein PhnI GO:0019634 MIM_c06110 0665b8589c810621950fa99e918add85 412 Pfam PF05861 Bacterial phosphonate metabolism protein (PhnI) 1 386 1.6E-160 T 12-10-2018 IPR008773 Phosphonate metabolism protein PhnI GO:0019634 MIM_c23840 b082fd8eab53ec115c552d5c4de74606 502 SMART SM00228 413 491 1.9E-7 T 12-10-2018 IPR001478 PDZ domain GO:0005515 MIM_c23840 b082fd8eab53ec115c552d5c4de74606 502 SMART SM00228 298 380 5.7E-9 T 12-10-2018 IPR001478 PDZ domain GO:0005515 MIM_c23840 b082fd8eab53ec115c552d5c4de74606 502 SUPERFAMILY SSF50156 256 380 2.63E-22 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 MIM_c23840 b082fd8eab53ec115c552d5c4de74606 502 SUPERFAMILY SSF50494 50 290 4.82E-66 T 12-10-2018 IPR009003 Peptidase S1, PA clan MIM_c23840 b082fd8eab53ec115c552d5c4de74606 502 Gene3D G3DSA:2.40.10.120 50 291 1.1E-80 T 12-10-2018 MIM_c23840 b082fd8eab53ec115c552d5c4de74606 502 PRINTS PR00834 HtrA/DegQ protease family signature 137 149 1.1E-54 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MIM_c23840 b082fd8eab53ec115c552d5c4de74606 502 PRINTS PR00834 HtrA/DegQ protease family signature 158 178 1.1E-54 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MIM_c23840 b082fd8eab53ec115c552d5c4de74606 502 PRINTS PR00834 HtrA/DegQ protease family signature 252 269 1.1E-54 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MIM_c23840 b082fd8eab53ec115c552d5c4de74606 502 PRINTS PR00834 HtrA/DegQ protease family signature 198 222 1.1E-54 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MIM_c23840 b082fd8eab53ec115c552d5c4de74606 502 PRINTS PR00834 HtrA/DegQ protease family signature 338 350 1.1E-54 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MIM_c23840 b082fd8eab53ec115c552d5c4de74606 502 PRINTS PR00834 HtrA/DegQ protease family signature 230 247 1.1E-54 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MIM_c23840 b082fd8eab53ec115c552d5c4de74606 502 Pfam PF13180 PDZ domain 421 498 1.3E-6 T 12-10-2018 IPR001478 PDZ domain GO:0005515 MIM_c23840 b082fd8eab53ec115c552d5c4de74606 502 Pfam PF13180 PDZ domain 298 389 2.5E-16 T 12-10-2018 IPR001478 PDZ domain GO:0005515 MIM_c23840 b082fd8eab53ec115c552d5c4de74606 502 Pfam PF13365 Trypsin-like peptidase domain 128 259 6.0E-36 T 12-10-2018 MIM_c23840 b082fd8eab53ec115c552d5c4de74606 502 Gene3D G3DSA:2.30.42.10 293 399 2.8E-26 T 12-10-2018 MIM_c23840 b082fd8eab53ec115c552d5c4de74606 502 Gene3D G3DSA:2.30.42.10 411 502 5.1E-14 T 12-10-2018 MIM_c23840 b082fd8eab53ec115c552d5c4de74606 502 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 51 494 3.7E-148 T 12-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 MIM_c23840 b082fd8eab53ec115c552d5c4de74606 502 SUPERFAMILY SSF50156 415 501 1.45E-12 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 MIM_c39320 ae1aa68e6aa90740b628b004c5e5b1cf 239 SUPERFAMILY SSF52540 5 232 5.23E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c39320 ae1aa68e6aa90740b628b004c5e5b1cf 239 SMART SM00382 30 205 3.4E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c39320 ae1aa68e6aa90740b628b004c5e5b1cf 239 Pfam PF00005 ABC transporter 21 166 2.0E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c39320 ae1aa68e6aa90740b628b004c5e5b1cf 239 Gene3D G3DSA:3.40.50.300 2 239 6.8E-56 T 12-10-2018 MIM_c39320 ae1aa68e6aa90740b628b004c5e5b1cf 239 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c32800 ff507bdf9555018a74b5fc75950a4b5f 723 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 445 589 4.3E-18 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MIM_c32800 ff507bdf9555018a74b5fc75950a4b5f 723 SUPERFAMILY SSF52518 21 208 2.7E-27 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c32800 ff507bdf9555018a74b5fc75950a4b5f 723 SUPERFAMILY SSF52518 413 612 1.46E-28 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c32800 ff507bdf9555018a74b5fc75950a4b5f 723 Gene3D G3DSA:3.40.50.970 436 618 1.0E-14 T 12-10-2018 MIM_c32800 ff507bdf9555018a74b5fc75950a4b5f 723 Gene3D G3DSA:3.40.50.970 3 201 1.2E-23 T 12-10-2018 MIM_c36650 c562b8c793264890615a4b77d9585635 344 Gene3D G3DSA:1.10.8.450 245 264 8.1E-47 T 12-10-2018 MIM_c36650 c562b8c793264890615a4b77d9585635 344 Pfam PF09084 NMT1/THI5 like 56 250 3.7E-16 T 12-10-2018 IPR015168 SsuA/THI5-like MIM_c36650 c562b8c793264890615a4b77d9585635 344 SMART SM00062 30 272 3.2E-5 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c36650 c562b8c793264890615a4b77d9585635 344 Gene3D G3DSA:3.40.190.10 111 209 8.1E-47 T 12-10-2018 MIM_c36650 c562b8c793264890615a4b77d9585635 344 SUPERFAMILY SSF53850 29 253 1.8E-42 T 12-10-2018 MIM_c36650 c562b8c793264890615a4b77d9585635 344 TIGRFAM TIGR01729 taurine_ABC_bnd: taurine ABC transporter, periplasmic binding protein 31 337 4.4E-132 T 12-10-2018 IPR010068 Taurine ABC transporter, substrate-binding protein TauA GO:0015734|GO:0042597 MIM_c36650 c562b8c793264890615a4b77d9585635 344 Gene3D G3DSA:3.40.190.10 32 244 8.1E-47 T 12-10-2018 MIM_c26890 6a9dc69f186f23398799575c4d889e7e 218 SUPERFAMILY SSF110857 43 153 5.1E-10 T 12-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily MIM_c26890 6a9dc69f186f23398799575c4d889e7e 218 Gene3D G3DSA:3.10.490.10 28 211 4.7E-12 T 12-10-2018 MIM_c26890 6a9dc69f186f23398799575c4d889e7e 218 Pfam PF04752 ChaC-like protein 43 210 2.8E-46 T 12-10-2018 IPR006840 Glutathione-specific gamma-glutamylcyclotransferase GO:0003839|GO:0006751 KEGG: 00480+4.3.2.7|MetaCyc: PWY-7942|Reactome: R-HSA-174403 MIM_c29890 582e42904fc4ac802543bf704a0f28b9 104 Pfam PF05164 Cell division protein ZapA 4 92 4.0E-16 T 12-10-2018 IPR007838 Cell division protein ZapA-like MIM_c29890 582e42904fc4ac802543bf704a0f28b9 104 SUPERFAMILY SSF102829 3 96 2.09E-15 T 12-10-2018 IPR036192 Cell division protein ZapA-like superfamily MIM_c29890 582e42904fc4ac802543bf704a0f28b9 104 Gene3D G3DSA:1.10.20.30 1 44 2.2E-9 T 12-10-2018 MIM_c29910 01348d2272f197c00a56c980c34a1402 303 SUPERFAMILY SSF51735 15 177 4.53E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c29910 01348d2272f197c00a56c980c34a1402 303 Gene3D G3DSA:1.10.1040.10 177 302 4.3E-38 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MIM_c29910 01348d2272f197c00a56c980c34a1402 303 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 19 32 - T 12-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 MIM_c29910 01348d2272f197c00a56c980c34a1402 303 PIRSF PIRSF000103 10 302 3.4E-68 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 MIM_c29910 01348d2272f197c00a56c980c34a1402 303 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 16 174 7.7E-46 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 MIM_c29910 01348d2272f197c00a56c980c34a1402 303 Gene3D G3DSA:3.40.50.720 10 176 1.1E-49 T 12-10-2018 MIM_c29910 01348d2272f197c00a56c980c34a1402 303 SUPERFAMILY SSF48179 177 300 5.1E-39 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c29910 01348d2272f197c00a56c980c34a1402 303 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 179 297 5.8E-34 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MIM_c26330 f72827f7f4a5c387e991e90828bd447b 354 Pfam PF01594 AI-2E family transporter 19 340 3.2E-51 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like MIM_c18300 92b5a091f5eb114a10a643354bf06cd0 231 Pfam PF03741 Integral membrane protein TerC family 14 183 8.4E-44 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 MIM_c18300 92b5a091f5eb114a10a643354bf06cd0 231 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 11 185 1.1E-67 T 12-10-2018 IPR022301 Integral membrane protein YjbE MIM_c37420 da3b14d699debfa4e1fea5bafe9a184a 196 SUPERFAMILY SSF51182 17 189 7.79E-35 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c37420 da3b14d699debfa4e1fea5bafe9a184a 196 Gene3D G3DSA:2.60.120.10 48 188 1.2E-24 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c09810 433e282b4715787a87cf9a23c09dc7c7 407 SUPERFAMILY SSF55307 206 320 1.24E-37 T 12-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 MIM_c09810 433e282b4715787a87cf9a23c09dc7c7 407 SMART SM00865 206 324 8.6E-46 T 12-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 MIM_c09810 433e282b4715787a87cf9a23c09dc7c7 407 Gene3D G3DSA:3.30.1330.20 220 327 1.5E-32 T 12-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 MIM_c09810 433e282b4715787a87cf9a23c09dc7c7 407 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 16 172 1.2E-34 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MIM_c09810 433e282b4715787a87cf9a23c09dc7c7 407 Pfam PF12327 FtsZ family, C-terminal domain 221 315 4.3E-29 T 12-10-2018 IPR024757 Cell division protein FtsZ, C-terminal MIM_c09810 433e282b4715787a87cf9a23c09dc7c7 407 SMART SM00864 15 204 9.8E-100 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MIM_c09810 433e282b4715787a87cf9a23c09dc7c7 407 PRINTS PR00423 Cell division protein FtsZ signature 97 117 3.0E-45 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MIM_c09810 433e282b4715787a87cf9a23c09dc7c7 407 PRINTS PR00423 Cell division protein FtsZ signature 125 146 3.0E-45 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MIM_c09810 433e282b4715787a87cf9a23c09dc7c7 407 PRINTS PR00423 Cell division protein FtsZ signature 188 210 3.0E-45 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MIM_c09810 433e282b4715787a87cf9a23c09dc7c7 407 PRINTS PR00423 Cell division protein FtsZ signature 211 232 3.0E-45 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MIM_c09810 433e282b4715787a87cf9a23c09dc7c7 407 Gene3D G3DSA:3.40.50.1440 5 218 8.3E-72 T 12-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 MIM_c09810 433e282b4715787a87cf9a23c09dc7c7 407 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 11 337 34.13 T 12-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 MIM_c09810 433e282b4715787a87cf9a23c09dc7c7 407 SUPERFAMILY SSF52490 15 207 1.7E-61 T 12-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 MIM_c09810 433e282b4715787a87cf9a23c09dc7c7 407 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 10 319 9.9E-114 T 12-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 MIM_c13530 386b0fedacd968d6689af3f6593867ee 552 TIGRFAM TIGR01838 PHA_synth_I: poly(R)-hydroxyalkanoic acid synthase, class I 23 550 2.2E-207 T 12-10-2018 IPR010963 Poly(R)-hydroxyalkanoic acid synthase, class I GO:0005737|GO:0016746|GO:0042619 MIM_c13530 386b0fedacd968d6689af3f6593867ee 552 Pfam PF07167 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus 59 226 3.1E-63 T 12-10-2018 IPR010941 Poly-beta-hydroxybutyrate polymerase, N-terminal domain GO:0042619 MIM_c13530 386b0fedacd968d6689af3f6593867ee 552 SUPERFAMILY SSF53474 186 478 1.2E-40 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c13530 386b0fedacd968d6689af3f6593867ee 552 Gene3D G3DSA:3.40.50.1820 185 448 2.1E-11 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c01670 9393d6038b98dba14a2abd9a66b57add 276 Gene3D G3DSA:3.40.50.1820 4 263 3.0E-35 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c01670 9393d6038b98dba14a2abd9a66b57add 276 Pfam PF00561 alpha/beta hydrolase fold 36 133 7.9E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c01670 9393d6038b98dba14a2abd9a66b57add 276 SUPERFAMILY SSF53474 14 259 1.34E-32 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c19600 315cc94375809073d365ed236e64c613 209 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 192 6.8E-49 T 12-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 MIM_c19600 315cc94375809073d365ed236e64c613 209 SUPERFAMILY SSF52540 1 201 4.54E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c19600 315cc94375809073d365ed236e64c613 209 Pfam PF02223 Thymidylate kinase 8 193 1.4E-45 T 12-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 MIM_c19600 315cc94375809073d365ed236e64c613 209 Gene3D G3DSA:3.40.50.300 1 206 1.2E-62 T 12-10-2018 MIM_c19600 315cc94375809073d365ed236e64c613 209 Hamap MF_00165 Thymidylate kinase [tmk]. 4 202 28.516 T 12-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 MIM_c18500 c5f80320473c3a7cab2df4d8fe8169c1 342 Pfam PF00296 Luciferase-like monooxygenase 16 300 7.6E-33 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MIM_c18500 c5f80320473c3a7cab2df4d8fe8169c1 342 SUPERFAMILY SSF51679 2 323 2.09E-86 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MIM_c18500 c5f80320473c3a7cab2df4d8fe8169c1 342 Gene3D G3DSA:3.20.20.30 1 328 1.0E-97 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MIM_c18500 c5f80320473c3a7cab2df4d8fe8169c1 342 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 4 323 5.1E-134 T 12-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 MIM_c19470 79dd2d6e6ba04854472acc6bc3442570 218 Pfam PF01351 Ribonuclease HII 21 202 9.3E-33 T 12-10-2018 IPR024567 Ribonuclease HII/HIII domain MIM_c19470 79dd2d6e6ba04854472acc6bc3442570 218 SUPERFAMILY SSF53098 19 209 2.12E-61 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily MIM_c19470 79dd2d6e6ba04854472acc6bc3442570 218 Gene3D G3DSA:3.30.420.10 16 217 2.7E-69 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MIM_c19470 79dd2d6e6ba04854472acc6bc3442570 218 Hamap MF_00052_B Ribonuclease HII [rnhB]. 19 204 33.467 T 12-10-2018 IPR022898 Ribonuclease HII GO:0004523 MIM_c03650 3914379b8aaa2395ca28ca6213c7db71 556 Gene3D G3DSA:1.20.200.10 236 554 8.4E-72 T 12-10-2018 MIM_c03650 3914379b8aaa2395ca28ca6213c7db71 556 SUPERFAMILY SSF48557 34 555 1.33E-123 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 MIM_c03650 3914379b8aaa2395ca28ca6213c7db71 556 Pfam PF00221 Aromatic amino acid lyase 37 529 2.9E-123 T 12-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 MIM_c03650 3914379b8aaa2395ca28ca6213c7db71 556 Gene3D G3DSA:1.10.275.10 22 234 1.3E-56 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal MIM_c25370 954d58d7cbc8898f7e4258b57d12e4b8 440 ProSitePatterns PS00216 Sugar transport proteins signature 1. 76 91 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MIM_c25370 954d58d7cbc8898f7e4258b57d12e4b8 440 ProSitePatterns PS00217 Sugar transport proteins signature 2. 118 143 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MIM_c25370 954d58d7cbc8898f7e4258b57d12e4b8 440 Pfam PF07690 Major Facilitator Superfamily 31 309 9.0E-36 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c25370 954d58d7cbc8898f7e4258b57d12e4b8 440 Gene3D G3DSA:1.20.1250.20 21 424 9.4E-71 T 12-10-2018 MIM_c25370 954d58d7cbc8898f7e4258b57d12e4b8 440 SUPERFAMILY SSF103473 5 429 3.27E-77 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c08010 ac32ef83e82404a361cd434cf311e763 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 63 3.3E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c08010 ac32ef83e82404a361cd434cf311e763 315 Gene3D G3DSA:3.40.190.290 97 296 1.2E-36 T 12-10-2018 MIM_c08010 ac32ef83e82404a361cd434cf311e763 315 Pfam PF03466 LysR substrate binding domain 96 292 3.1E-33 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c08010 ac32ef83e82404a361cd434cf311e763 315 Gene3D G3DSA:1.10.10.10 6 96 3.3E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c08010 ac32ef83e82404a361cd434cf311e763 315 SUPERFAMILY SSF46785 7 89 8.71E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c08010 ac32ef83e82404a361cd434cf311e763 315 SUPERFAMILY SSF53850 97 301 1.3E-30 T 12-10-2018 MIM_c41170 98ff3ee810e1f64b5cbfa3d0fa094eca 559 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 368 547 1.1E-68 T 12-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c41170 98ff3ee810e1f64b5cbfa3d0fa094eca 559 PRINTS PR00701 60kDa inner membrane protein signature 430 453 9.4E-68 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MIM_c41170 98ff3ee810e1f64b5cbfa3d0fa094eca 559 PRINTS PR00701 60kDa inner membrane protein signature 231 249 9.4E-68 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MIM_c41170 98ff3ee810e1f64b5cbfa3d0fa094eca 559 PRINTS PR00701 60kDa inner membrane protein signature 177 197 9.4E-68 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MIM_c41170 98ff3ee810e1f64b5cbfa3d0fa094eca 559 PRINTS PR00701 60kDa inner membrane protein signature 266 281 9.4E-68 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MIM_c41170 98ff3ee810e1f64b5cbfa3d0fa094eca 559 PRINTS PR00701 60kDa inner membrane protein signature 339 359 9.4E-68 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MIM_c41170 98ff3ee810e1f64b5cbfa3d0fa094eca 559 PRINTS PR00701 60kDa inner membrane protein signature 477 499 9.4E-68 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MIM_c41170 98ff3ee810e1f64b5cbfa3d0fa094eca 559 PRINTS PR00701 60kDa inner membrane protein signature 2 23 9.4E-68 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MIM_c41170 98ff3ee810e1f64b5cbfa3d0fa094eca 559 PRINTS PR00701 60kDa inner membrane protein signature 513 536 9.4E-68 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MIM_c41170 98ff3ee810e1f64b5cbfa3d0fa094eca 559 PRINTS PR00701 60kDa inner membrane protein signature 88 109 9.4E-68 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MIM_c41170 98ff3ee810e1f64b5cbfa3d0fa094eca 559 Gene3D G3DSA:2.70.98.90 79 348 1.4E-78 T 12-10-2018 IPR038221 YidC, periplasmic domain superfamily MIM_c41170 98ff3ee810e1f64b5cbfa3d0fa094eca 559 Pfam PF14849 YidC periplasmic domain 83 357 6.6E-79 T 12-10-2018 IPR038210 Membrane insertase YidC, periplasmic domain MIM_c41170 98ff3ee810e1f64b5cbfa3d0fa094eca 559 PRINTS PR01900 YidC translocation/secretion protein signature 502 526 1.0E-21 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MIM_c41170 98ff3ee810e1f64b5cbfa3d0fa094eca 559 PRINTS PR01900 YidC translocation/secretion protein signature 483 498 1.0E-21 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MIM_c41170 98ff3ee810e1f64b5cbfa3d0fa094eca 559 PRINTS PR01900 YidC translocation/secretion protein signature 354 370 1.0E-21 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MIM_c41170 98ff3ee810e1f64b5cbfa3d0fa094eca 559 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 3 367 2.0E-110 T 12-10-2018 IPR028053 Membrane insertase YidC, N-terminal MIM_c41170 98ff3ee810e1f64b5cbfa3d0fa094eca 559 Pfam PF02096 60Kd inner membrane protein 369 547 5.5E-59 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MIM_c41170 98ff3ee810e1f64b5cbfa3d0fa094eca 559 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 4 549 24.507 T 12-10-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0032977 MIM_c25080 9fa43bad8fe0e42984eb7cef8d4c64d8 155 Pfam PF01638 HxlR-like helix-turn-helix 20 106 4.3E-22 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type MIM_c25080 9fa43bad8fe0e42984eb7cef8d4c64d8 155 SUPERFAMILY SSF46785 5 136 1.16E-36 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c25080 9fa43bad8fe0e42984eb7cef8d4c64d8 155 Gene3D G3DSA:1.10.10.10 1 154 8.7E-46 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c10820 44e11e3fd79e074c0a7424a481148e94 288 Pfam PF00574 Clp protease 68 197 1.0E-24 T 12-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA MIM_c10820 44e11e3fd79e074c0a7424a481148e94 288 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 102 113 - T 12-10-2018 IPR018215 ClpP, Ser active site MIM_c10820 44e11e3fd79e074c0a7424a481148e94 288 Gene3D G3DSA:3.90.226.10 31 219 5.2E-42 T 12-10-2018 MIM_c10820 44e11e3fd79e074c0a7424a481148e94 288 PRINTS PR00127 Clp protease catalytic subunit P signature 102 119 3.1E-10 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MIM_c10820 44e11e3fd79e074c0a7424a481148e94 288 PRINTS PR00127 Clp protease catalytic subunit P signature 71 91 3.1E-10 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MIM_c10820 44e11e3fd79e074c0a7424a481148e94 288 SUPERFAMILY SSF52096 36 204 1.92E-41 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c12020 a8d67163e1ab3befe92362d3e4e09637 139 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 33 119 1.3E-10 T 12-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 MIM_c12020 a8d67163e1ab3befe92362d3e4e09637 139 Gene3D G3DSA:3.10.129.10 1 139 6.2E-43 T 12-10-2018 MIM_c12020 a8d67163e1ab3befe92362d3e4e09637 139 SUPERFAMILY SSF54637 7 138 6.8E-26 T 12-10-2018 IPR029069 HotDog domain superfamily MIM_c12020 a8d67163e1ab3befe92362d3e4e09637 139 Pfam PF03061 Thioesterase superfamily 51 127 1.4E-15 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MIM_c06660 29df000776e8a1b0a936f6d83d37593e 92 Pfam PF05015 RelE-like toxin of type II toxin-antitoxin system HigB 3 92 9.6E-24 T 12-10-2018 IPR007711 Toxin HigB-1 MIM_c06660 29df000776e8a1b0a936f6d83d37593e 92 Gene3D G3DSA:3.30.2310.20 1 92 4.5E-33 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MIM_c06660 29df000776e8a1b0a936f6d83d37593e 92 SUPERFAMILY SSF143011 3 92 4.84E-14 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MIM_24p00150 897a3de2e2e14da390dbd6529dfa684f 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 3.8E-12 T 12-10-2018 MIM_24p00150 897a3de2e2e14da390dbd6529dfa684f 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 288 303 3.8E-12 T 12-10-2018 MIM_24p00150 897a3de2e2e14da390dbd6529dfa684f 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 3.8E-12 T 12-10-2018 MIM_24p00150 897a3de2e2e14da390dbd6529dfa684f 396 SUPERFAMILY SSF54373 182 281 4.9E-17 T 12-10-2018 MIM_24p00150 897a3de2e2e14da390dbd6529dfa684f 396 Gene3D G3DSA:3.30.9.30 41 361 2.8E-117 T 12-10-2018 MIM_24p00150 897a3de2e2e14da390dbd6529dfa684f 396 Pfam PF01494 FAD binding domain 8 348 6.1E-22 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 MIM_24p00150 897a3de2e2e14da390dbd6529dfa684f 396 Gene3D G3DSA:3.50.50.60 9 353 2.8E-117 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_24p00150 897a3de2e2e14da390dbd6529dfa684f 396 SUPERFAMILY SSF51905 7 365 9.89E-59 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c32410 262a56f1ee22ce07f3d2b08202e4303d 201 SUPERFAMILY SSF53178 6 193 1.28E-61 T 12-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 MIM_c32410 262a56f1ee22ce07f3d2b08202e4303d 201 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 19 32 - T 12-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 MIM_c32410 262a56f1ee22ce07f3d2b08202e4303d 201 Pfam PF01195 Peptidyl-tRNA hydrolase 8 190 4.3E-54 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MIM_c32410 262a56f1ee22ce07f3d2b08202e4303d 201 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 113 123 - T 12-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 MIM_c32410 262a56f1ee22ce07f3d2b08202e4303d 201 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 6 187 34.002 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MIM_c32410 262a56f1ee22ce07f3d2b08202e4303d 201 Gene3D G3DSA:3.40.50.1470 6 197 6.0E-64 T 12-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 MIM_c32410 262a56f1ee22ce07f3d2b08202e4303d 201 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 7 192 1.3E-57 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MIM_c15820 c16eca9b14dd102a0f3bc1d7706c0c9d 363 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 30 353 5.1E-70 T 12-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 MIM_c15820 c16eca9b14dd102a0f3bc1d7706c0c9d 363 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 12 358 37.137 T 12-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 MIM_c15820 c16eca9b14dd102a0f3bc1d7706c0c9d 363 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 25 357 1.5E-97 T 12-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 MIM_c15820 c16eca9b14dd102a0f3bc1d7706c0c9d 363 SUPERFAMILY SSF52540 57 198 1.74E-10 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c26530 519bbea30353d6da889274417c66d9a4 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c26530 519bbea30353d6da889274417c66d9a4 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.0E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c26530 519bbea30353d6da889274417c66d9a4 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 4.0E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c26530 519bbea30353d6da889274417c66d9a4 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 4.0E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c26530 519bbea30353d6da889274417c66d9a4 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 4.0E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c26530 519bbea30353d6da889274417c66d9a4 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 4.0E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c26530 519bbea30353d6da889274417c66d9a4 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 4.0E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c26530 519bbea30353d6da889274417c66d9a4 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 4.2E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c26530 519bbea30353d6da889274417c66d9a4 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 4.2E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c26530 519bbea30353d6da889274417c66d9a4 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 4.2E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c26530 519bbea30353d6da889274417c66d9a4 246 Gene3D G3DSA:3.40.50.720 1 245 3.0E-74 T 12-10-2018 MIM_c26530 519bbea30353d6da889274417c66d9a4 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 246 8.4E-55 T 12-10-2018 MIM_c26530 519bbea30353d6da889274417c66d9a4 246 SUPERFAMILY SSF51735 7 245 4.06E-74 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c26530 519bbea30353d6da889274417c66d9a4 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 192 3.0E-6 T 12-10-2018 MIM_c05680 b09d009baaa892ae7a04267114392e08 231 SMART SM00862 150 225 1.2E-27 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MIM_c05680 b09d009baaa892ae7a04267114392e08 231 SUPERFAMILY SSF46894 124 226 2.47E-31 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MIM_c05680 b09d009baaa892ae7a04267114392e08 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 4.4E-27 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MIM_c05680 b09d009baaa892ae7a04267114392e08 231 SUPERFAMILY SSF52172 4 126 4.84E-42 T 12-10-2018 IPR011006 CheY-like superfamily MIM_c05680 b09d009baaa892ae7a04267114392e08 231 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 1 226 2.2E-109 T 12-10-2018 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 MIM_c05680 b09d009baaa892ae7a04267114392e08 231 Gene3D G3DSA:3.40.50.2300 2 128 1.9E-38 T 12-10-2018 MIM_c05680 b09d009baaa892ae7a04267114392e08 231 SMART SM00448 3 116 1.6E-42 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c05680 b09d009baaa892ae7a04267114392e08 231 Gene3D G3DSA:1.10.10.10 129 229 2.3E-37 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c05680 b09d009baaa892ae7a04267114392e08 231 Pfam PF00072 Response regulator receiver domain 5 117 2.3E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c28900 0a4ee781a21afb7923dd501c4ffb2b35 226 SUPERFAMILY SSF53335 9 223 1.33E-34 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c28900 0a4ee781a21afb7923dd501c4ffb2b35 226 Gene3D G3DSA:3.40.50.150 5 225 2.5E-40 T 12-10-2018 MIM_c28900 0a4ee781a21afb7923dd501c4ffb2b35 226 Pfam PF13649 Methyltransferase domain 45 138 4.4E-14 T 12-10-2018 MIM_c22770 bfc6eb7cae4e5a2ba83b8f432d2a7389 125 Pfam PF06305 Lipopolysaccharide assembly protein A domain 22 86 2.3E-18 T 12-10-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 MIM_c32510 e98fd63e4b084871a05b65cc7c695f85 377 Gene3D G3DSA:3.40.50.2000 185 359 8.3E-54 T 12-10-2018 MIM_c32510 e98fd63e4b084871a05b65cc7c695f85 377 Gene3D G3DSA:3.40.50.2000 30 372 8.3E-54 T 12-10-2018 MIM_c32510 e98fd63e4b084871a05b65cc7c695f85 377 SUPERFAMILY SSF53756 27 375 8.9E-67 T 12-10-2018 MIM_c32510 e98fd63e4b084871a05b65cc7c695f85 377 Pfam PF00534 Glycosyl transferases group 1 195 352 5.4E-30 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 MIM_c32510 e98fd63e4b084871a05b65cc7c695f85 377 Pfam PF13477 Glycosyl transferase 4-like 10 159 2.5E-24 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MIM_c05430 a7311d3d943df35af38918503ea4e2d8 256 Pfam PF13098 Thioredoxin-like domain 129 250 2.7E-33 T 12-10-2018 IPR012336 Thioredoxin-like fold MIM_c05430 a7311d3d943df35af38918503ea4e2d8 256 SUPERFAMILY SSF52833 109 252 2.03E-32 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c05430 a7311d3d943df35af38918503ea4e2d8 256 ProSitePatterns PS00194 Thioredoxin family active site. 137 155 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MIM_c05430 a7311d3d943df35af38918503ea4e2d8 256 Gene3D G3DSA:3.40.30.10 101 253 1.0E-38 T 12-10-2018 MIM_c05430 a7311d3d943df35af38918503ea4e2d8 256 SUPERFAMILY SSF54423 54 103 1.29E-10 T 12-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 MIM_c05430 a7311d3d943df35af38918503ea4e2d8 256 Gene3D G3DSA:3.10.450.70 41 100 5.0E-7 T 12-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 MIM_c05430 a7311d3d943df35af38918503ea4e2d8 256 Pfam PF10411 Disulfide bond isomerase protein N-terminus 49 101 1.0E-16 T 12-10-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal MIM_c07690 9bdb1be0e81102125d770248f4ad8f07 336 SUPERFAMILY SSF53098 111 282 4.55E-19 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily MIM_c07690 9bdb1be0e81102125d770248f4ad8f07 336 Pfam PF13384 Homeodomain-like domain 6 32 7.8E-7 T 12-10-2018 MIM_c07690 9bdb1be0e81102125d770248f4ad8f07 336 Pfam PF00665 Integrase core domain 111 233 1.9E-24 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 MIM_c07690 9bdb1be0e81102125d770248f4ad8f07 336 Gene3D G3DSA:1.10.10.60 2 32 4.5E-6 T 12-10-2018 MIM_c07690 9bdb1be0e81102125d770248f4ad8f07 336 Gene3D G3DSA:3.30.420.10 109 277 2.1E-6 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MIM_c26840 7ab01d06a682637e0f857d7967d9fcae 310 SUPERFAMILY SSF53448 5 244 2.67E-37 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MIM_c26840 7ab01d06a682637e0f857d7967d9fcae 310 Pfam PF00535 Glycosyl transferase family 2 9 117 2.5E-25 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MIM_c26840 7ab01d06a682637e0f857d7967d9fcae 310 Gene3D G3DSA:3.90.550.10 1 240 3.5E-34 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MIM_c23500 ac1cc76f6d6298e9159437fd877d2936 55 SUPERFAMILY SSF57829 1 53 2.01E-19 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 MIM_c23500 ac1cc76f6d6298e9159437fd877d2936 55 Pfam PF00471 Ribosomal protein L33 7 53 3.6E-18 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c23500 ac1cc76f6d6298e9159437fd877d2936 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 55 1.6E-25 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c23500 ac1cc76f6d6298e9159437fd877d2936 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 5 53 14.926 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c23500 ac1cc76f6d6298e9159437fd877d2936 55 Gene3D G3DSA:2.20.28.120 1 55 1.7E-29 T 12-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c40240 24d3247786b3417b7ffc46b9d2d2732d 304 Pfam PF00892 EamA-like transporter family 155 287 5.0E-11 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MIM_c40240 24d3247786b3417b7ffc46b9d2d2732d 304 Pfam PF00892 EamA-like transporter family 16 143 2.8E-16 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MIM_c40240 24d3247786b3417b7ffc46b9d2d2732d 304 SUPERFAMILY SSF103481 213 288 7.59E-10 T 12-10-2018 MIM_c40240 24d3247786b3417b7ffc46b9d2d2732d 304 SUPERFAMILY SSF103481 49 146 2.68E-12 T 12-10-2018 MIM_c28660 25fbe78eaa786ef73c151ec94d71f641 240 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 2 231 2.2E-78 T 12-10-2018 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MIM_c28660 25fbe78eaa786ef73c151ec94d71f641 240 Pfam PF00929 Exonuclease 4 164 3.2E-30 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MIM_c28660 25fbe78eaa786ef73c151ec94d71f641 240 SUPERFAMILY SSF53098 1 175 1.88E-48 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily MIM_c28660 25fbe78eaa786ef73c151ec94d71f641 240 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 5 210 5.6E-50 T 12-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MIM_c28660 25fbe78eaa786ef73c151ec94d71f641 240 Gene3D G3DSA:3.30.420.10 1 179 8.3E-49 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MIM_c28660 25fbe78eaa786ef73c151ec94d71f641 240 SMART SM00479 2 174 2.7E-34 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MIM_c24250 d62186e4ea8323e904a0c6f254d7cceb 194 Pfam PF04279 Intracellular septation protein A 3 178 6.1E-61 T 12-10-2018 IPR006008 Intracellular septation protein A GO:0016021 MIM_c24250 d62186e4ea8323e904a0c6f254d7cceb 194 TIGRFAM TIGR00997 ispZ: intracellular septation protein A 3 177 1.9E-50 T 12-10-2018 IPR006008 Intracellular septation protein A GO:0016021 MIM_c24250 d62186e4ea8323e904a0c6f254d7cceb 194 Hamap MF_00189 Probable intracellular septation protein A [yciB]. 2 179 17.903 T 12-10-2018 IPR006008 Intracellular septation protein A GO:0016021 MIM_c03400 26645565707f6dd9759bed524b160dc5 290 Gene3D G3DSA:3.40.190.10 103 282 1.3E-41 T 12-10-2018 MIM_c03400 26645565707f6dd9759bed524b160dc5 290 Pfam PF03466 LysR substrate binding domain 94 287 1.2E-28 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c03400 26645565707f6dd9759bed524b160dc5 290 SUPERFAMILY SSF53850 94 288 7.24E-32 T 12-10-2018 MIM_c03400 26645565707f6dd9759bed524b160dc5 290 Gene3D G3DSA:3.40.190.10 164 256 1.3E-41 T 12-10-2018 MIM_c03400 26645565707f6dd9759bed524b160dc5 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 1.5E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c03400 26645565707f6dd9759bed524b160dc5 290 SUPERFAMILY SSF46785 7 86 5.62E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c03400 26645565707f6dd9759bed524b160dc5 290 Gene3D G3DSA:1.10.10.10 9 99 4.9E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c03400 26645565707f6dd9759bed524b160dc5 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 1.9E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c03400 26645565707f6dd9759bed524b160dc5 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 1.9E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c03400 26645565707f6dd9759bed524b160dc5 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 1.9E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c22430 6e8d786c957e80b30e9dc6012e4d5978 343 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 41 286 2.6E-65 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 MIM_c22430 6e8d786c957e80b30e9dc6012e4d5978 343 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 41 316 2.0E-72 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 MIM_c22430 6e8d786c957e80b30e9dc6012e4d5978 343 Gene3D G3DSA:3.40.190.170 34 343 1.4E-105 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily MIM_c22430 6e8d786c957e80b30e9dc6012e4d5978 343 PIRSF PIRSF006470 7 340 4.3E-70 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 MIM_c28570 762b6d423ccd94f11a80eb9d8d010d11 100 Pfam PF11390 NADH-dependant formate dehydrogenase delta subunit FdsD 13 78 2.6E-24 T 12-10-2018 IPR021074 Formate dehydrogenase, delta subunit MIM_c30130 6aa664c8952fde3837c3f6667fe6ade1 330 SUPERFAMILY SSF51556 7 321 2.52E-82 T 12-10-2018 IPR032466 Metal-dependent hydrolase MIM_c30130 6aa664c8952fde3837c3f6667fe6ade1 330 Pfam PF00962 Adenosine/AMP deaminase 12 320 1.5E-69 T 12-10-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 MIM_c30130 6aa664c8952fde3837c3f6667fe6ade1 330 Hamap MF_01962 Adenine deaminase. 8 324 81.178 T 12-10-2018 IPR028892 Adenine deaminase type 2 GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 MIM_c30130 6aa664c8952fde3837c3f6667fe6ade1 330 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 12 322 3.4E-105 T 12-10-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 MIM_c30130 6aa664c8952fde3837c3f6667fe6ade1 330 Gene3D G3DSA:3.20.20.140 2 324 3.2E-96 T 12-10-2018 MIM_c31780 4d5d4e2f72dd3c6c3eee7980e7045f29 324 PIRSF PIRSF017082 1 324 7.5E-68 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c31780 4d5d4e2f72dd3c6c3eee7980e7045f29 324 Gene3D G3DSA:3.40.190.10 127 250 3.2E-93 T 12-10-2018 MIM_c31780 4d5d4e2f72dd3c6c3eee7980e7045f29 324 SUPERFAMILY SSF53850 119 289 1.74E-10 T 12-10-2018 MIM_c31780 4d5d4e2f72dd3c6c3eee7980e7045f29 324 Gene3D G3DSA:3.40.190.150 30 314 3.2E-93 T 12-10-2018 MIM_c31780 4d5d4e2f72dd3c6c3eee7980e7045f29 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 319 9.5E-66 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c03350 c23f68a49d280d3a67ad55fb473c1978 209 SUPERFAMILY SSF47616 74 199 1.66E-9 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MIM_c03350 c23f68a49d280d3a67ad55fb473c1978 209 Gene3D G3DSA:1.20.1050.10 86 197 1.8E-57 T 12-10-2018 MIM_c03350 c23f68a49d280d3a67ad55fb473c1978 209 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 81 1.2E-14 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MIM_c03350 c23f68a49d280d3a67ad55fb473c1978 209 Gene3D G3DSA:3.40.30.10 4 199 1.8E-57 T 12-10-2018 MIM_c03350 c23f68a49d280d3a67ad55fb473c1978 209 SUPERFAMILY SSF52833 2 94 1.05E-15 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c28110 0db5c190110242fb76ed2eb17176a4a3 329 PIRSF PIRSF017082 1 328 3.1E-72 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c28110 0db5c190110242fb76ed2eb17176a4a3 329 Gene3D G3DSA:3.40.190.10 131 254 1.4E-108 T 12-10-2018 MIM_c28110 0db5c190110242fb76ed2eb17176a4a3 329 Gene3D G3DSA:3.40.190.150 33 319 1.4E-108 T 12-10-2018 MIM_c28110 0db5c190110242fb76ed2eb17176a4a3 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 324 2.0E-81 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c28110 0db5c190110242fb76ed2eb17176a4a3 329 SUPERFAMILY SSF53850 114 276 8.68E-6 T 12-10-2018 MIM_c00600 579aff04c298d9480db23c3edb5e1d0a 134 SUPERFAMILY SSF143744 2 132 1.96E-30 T 12-10-2018 IPR038084 GlcG-like domain superfamily MIM_c00600 579aff04c298d9480db23c3edb5e1d0a 134 Pfam PF03928 Haem-degrading 2 130 1.5E-23 T 12-10-2018 IPR005624 Haem-degrading MIM_c00600 579aff04c298d9480db23c3edb5e1d0a 134 Gene3D G3DSA:3.30.450.150 1 133 1.2E-30 T 12-10-2018 IPR038084 GlcG-like domain superfamily MIM_c10000 07788edc676b9f06b32438a45cfdc040 281 Pfam PF01497 Periplasmic binding protein 31 255 2.0E-43 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain MIM_c10000 07788edc676b9f06b32438a45cfdc040 281 Gene3D G3DSA:3.40.50.1980 24 144 4.1E-43 T 12-10-2018 MIM_c10000 07788edc676b9f06b32438a45cfdc040 281 SUPERFAMILY SSF53807 27 273 2.79E-56 T 12-10-2018 MIM_c10000 07788edc676b9f06b32438a45cfdc040 281 Gene3D G3DSA:3.40.50.1980 145 279 2.8E-36 T 12-10-2018 MIM_c31690 059379345759ada69f65f5ae6765bf42 310 SUPERFAMILY SSF46626 168 264 1.26E-20 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c31690 059379345759ada69f65f5ae6765bf42 310 SUPERFAMILY SSF46626 45 151 2.83E-26 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c31690 059379345759ada69f65f5ae6765bf42 310 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 172 251 7.6E-9 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c31690 059379345759ada69f65f5ae6765bf42 310 Gene3D G3DSA:1.10.760.10 161 275 1.5E-41 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c31690 059379345759ada69f65f5ae6765bf42 310 Gene3D G3DSA:1.10.760.10 28 158 2.2E-39 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c12320 b49897717038548af3ac8d926afd4875 287 Gene3D G3DSA:3.40.190.10 124 228 3.4E-58 T 12-10-2018 MIM_c12320 b49897717038548af3ac8d926afd4875 287 SUPERFAMILY SSF53850 5 266 2.8E-42 T 12-10-2018 MIM_c12320 b49897717038548af3ac8d926afd4875 287 SMART SM00062 38 269 1.5E-37 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c12320 b49897717038548af3ac8d926afd4875 287 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 266 1.5E-40 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c12320 b49897717038548af3ac8d926afd4875 287 TIGRFAM TIGR02995 ectoine_ehuB: ectoine/hydroxyectoine ABC transporter solute-binding protein EhuB 11 284 6.5E-84 T 12-10-2018 IPR014337 Ectoine/Hydroxyectoine ABC transporter, substrate-binding protein EhuB GO:0033294|GO:0051470 MIM_c12320 b49897717038548af3ac8d926afd4875 287 Gene3D G3DSA:3.40.190.10 45 262 3.4E-58 T 12-10-2018 MIM_c05760 fad2d686a8e30461b95c003ba9963f89 523 SUPERFAMILY SSF56112 91 436 2.03E-43 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily MIM_c05760 fad2d686a8e30461b95c003ba9963f89 523 Pfam PF03109 ABC1 family 109 230 3.5E-32 T 12-10-2018 IPR004147 UbiB domain MIM_c05760 fad2d686a8e30461b95c003ba9963f89 523 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 6 444 1.3E-173 T 12-10-2018 IPR010232 Probable protein kinase UbiB GO:0006744 MIM_c31250 ecde322b2fbf887e5ce87a82510307d2 213 Pfam PF06532 Protein of unknown function (DUF1109) 18 213 3.4E-61 T 12-10-2018 IPR009495 Anti-sigma-F factor NrsF MIM_c34270 5b698991cae82438aa7d71f5a8ad340e 424 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 29 403 1.7E-66 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MIM_c34270 5b698991cae82438aa7d71f5a8ad340e 424 SUPERFAMILY SSF53335 25 404 2.0E-96 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c34270 5b698991cae82438aa7d71f5a8ad340e 424 Pfam PF00145 C-5 cytosine-specific DNA methylase 26 406 2.4E-73 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MIM_c34270 5b698991cae82438aa7d71f5a8ad340e 424 Gene3D G3DSA:3.90.120.10 283 397 2.7E-27 T 12-10-2018 MIM_c34270 5b698991cae82438aa7d71f5a8ad340e 424 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 182 195 3.1E-15 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MIM_c34270 5b698991cae82438aa7d71f5a8ad340e 424 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 136 150 3.1E-15 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MIM_c34270 5b698991cae82438aa7d71f5a8ad340e 424 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 27 43 3.1E-15 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MIM_c34270 5b698991cae82438aa7d71f5a8ad340e 424 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 97 109 - T 12-10-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-4655427|Reactome: R-HSA-5334118 MIM_c34270 5b698991cae82438aa7d71f5a8ad340e 424 Gene3D G3DSA:3.40.50.150 3 245 1.5E-65 T 12-10-2018 MIM_c39150 23aa566e5a1b4ea1e334a8c614fddb26 529 Pfam PF01019 Gamma-glutamyltranspeptidase 36 524 1.0E-149 T 12-10-2018 MIM_c39150 23aa566e5a1b4ea1e334a8c614fddb26 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 349 367 1.4E-37 T 12-10-2018 MIM_c39150 23aa566e5a1b4ea1e334a8c614fddb26 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 43 68 1.4E-37 T 12-10-2018 MIM_c39150 23aa566e5a1b4ea1e334a8c614fddb26 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 404 419 1.4E-37 T 12-10-2018 MIM_c39150 23aa566e5a1b4ea1e334a8c614fddb26 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 428 445 1.4E-37 T 12-10-2018 MIM_c39150 23aa566e5a1b4ea1e334a8c614fddb26 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 226 242 1.4E-37 T 12-10-2018 MIM_c39150 23aa566e5a1b4ea1e334a8c614fddb26 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 110 128 1.4E-37 T 12-10-2018 MIM_c39150 23aa566e5a1b4ea1e334a8c614fddb26 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 373 391 1.4E-37 T 12-10-2018 MIM_c39150 23aa566e5a1b4ea1e334a8c614fddb26 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 128 147 1.4E-37 T 12-10-2018 MIM_c39150 23aa566e5a1b4ea1e334a8c614fddb26 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 255 274 1.4E-37 T 12-10-2018 MIM_c39150 23aa566e5a1b4ea1e334a8c614fddb26 529 Gene3D G3DSA:3.60.20.40 350 529 2.2E-65 T 12-10-2018 MIM_c39150 23aa566e5a1b4ea1e334a8c614fddb26 529 SUPERFAMILY SSF56235 9 529 7.52E-167 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MIM_c39150 23aa566e5a1b4ea1e334a8c614fddb26 529 Gene3D G3DSA:1.10.246.130 242 349 6.0E-27 T 12-10-2018 MIM_c15400 3ad1d01eb97cfca9af9ef479f872f3da 427 Gene3D G3DSA:3.20.20.10 49 292 5.7E-129 T 12-10-2018 IPR029066 PLP-binding barrel MIM_c15400 3ad1d01eb97cfca9af9ef479f872f3da 427 Pfam PF14031 Putative serine dehydratase domain 314 412 8.2E-17 T 12-10-2018 IPR026956 D-serine dehydratase-like domain MIM_c15400 3ad1d01eb97cfca9af9ef479f872f3da 427 Pfam PF01168 Alanine racemase, N-terminal domain 47 260 5.2E-14 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MIM_c15400 3ad1d01eb97cfca9af9ef479f872f3da 427 Gene3D G3DSA:2.40.37.20 30 427 5.7E-129 T 12-10-2018 MIM_c15400 3ad1d01eb97cfca9af9ef479f872f3da 427 SUPERFAMILY SSF51419 47 277 1.75E-27 T 12-10-2018 IPR029066 PLP-binding barrel MIM_c15400 3ad1d01eb97cfca9af9ef479f872f3da 427 SMART SM01119 314 414 1.3E-34 T 12-10-2018 IPR026956 D-serine dehydratase-like domain MIM_c06840 9d4df316b05d2fc193fd06ad16a2c6dd 474 Pfam PF00483 Nucleotidyl transferase 7 289 1.5E-57 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MIM_c06840 9d4df316b05d2fc193fd06ad16a2c6dd 474 SUPERFAMILY SSF51182 184 472 4.67E-83 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c06840 9d4df316b05d2fc193fd06ad16a2c6dd 474 Pfam PF01050 Mannose-6-phosphate isomerase 318 468 1.2E-68 T 12-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 MIM_c06840 9d4df316b05d2fc193fd06ad16a2c6dd 474 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 5 472 5.9E-176 T 12-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 MIM_c06840 9d4df316b05d2fc193fd06ad16a2c6dd 474 Gene3D G3DSA:3.90.550.10 4 348 8.7E-111 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MIM_c06840 9d4df316b05d2fc193fd06ad16a2c6dd 474 SUPERFAMILY SSF53448 6 281 1.22E-64 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MIM_c06840 9d4df316b05d2fc193fd06ad16a2c6dd 474 Gene3D G3DSA:2.60.120.10 349 461 2.8E-16 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c04790 5eafe10acd8c00e9908dba853e22e5b7 202 Gene3D G3DSA:3.10.450.50 39 175 1.5E-51 T 12-10-2018 MIM_c04790 5eafe10acd8c00e9908dba853e22e5b7 202 Pfam PF05494 MlaC protein 39 201 3.7E-51 T 12-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC MIM_c04790 5eafe10acd8c00e9908dba853e22e5b7 202 Gene3D G3DSA:1.10.10.640 76 200 1.5E-51 T 12-10-2018 MIM_c04790 5eafe10acd8c00e9908dba853e22e5b7 202 PIRSF PIRSF004649 6 202 1.2E-47 T 12-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC MIM_c08100 291b1ab2fd34c7bed6a2957a3d34aca0 510 Gene3D G3DSA:1.20.1250.20 28 463 1.7E-75 T 12-10-2018 MIM_c08100 291b1ab2fd34c7bed6a2957a3d34aca0 510 Pfam PF00083 Sugar (and other) transporter 31 450 1.7E-63 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MIM_c08100 291b1ab2fd34c7bed6a2957a3d34aca0 510 ProSitePatterns PS00216 Sugar transport proteins signature 1. 319 336 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MIM_c08100 291b1ab2fd34c7bed6a2957a3d34aca0 510 Pfam PF08946 Osmosensory transporter coiled coil 458 510 3.5E-21 T 12-10-2018 IPR015041 Osmosensory transporter coiled coil MIM_c08100 291b1ab2fd34c7bed6a2957a3d34aca0 510 TIGRFAM TIGR00883 2A0106: MFS transporter, metabolite:H+ symporter (MHS) family protein 37 435 1.2E-137 T 12-10-2018 IPR004736 MFS transporter, metabolite:H symporter GO:0016021|GO:0022857|GO:0055085 MIM_c08100 291b1ab2fd34c7bed6a2957a3d34aca0 510 SUPERFAMILY SSF103473 28 450 5.1E-74 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c05080 f9861305850a55d2b5081aa024a9a73a 149 SUPERFAMILY SSF109635 12 106 1.27E-26 T 12-10-2018 IPR037187 DksA, N-terminal domain superfamily MIM_c05080 f9861305850a55d2b5081aa024a9a73a 149 Gene3D G3DSA:1.20.120.910 16 148 2.8E-36 T 12-10-2018 MIM_c05080 f9861305850a55d2b5081aa024a9a73a 149 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 31 139 9.1E-41 T 12-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 MIM_c05080 f9861305850a55d2b5081aa024a9a73a 149 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 27 148 27.269 T 12-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 MIM_c05080 f9861305850a55d2b5081aa024a9a73a 149 SUPERFAMILY SSF57716 109 147 8.7E-9 T 12-10-2018 MIM_c05080 f9861305850a55d2b5081aa024a9a73a 149 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 112 136 - T 12-10-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site MIM_c05080 f9861305850a55d2b5081aa024a9a73a 149 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 107 142 1.0E-10 T 12-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 MIM_c37530 b69a4058398fa3a81764767971281f27 398 Gene3D G3DSA:3.40.50.10540 12 389 2.2E-112 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c37530 b69a4058398fa3a81764767971281f27 398 Gene3D G3DSA:3.30.1540.10 232 325 2.2E-112 T 12-10-2018 MIM_c37530 b69a4058398fa3a81764767971281f27 398 SUPERFAMILY SSF89796 9 397 5.89E-117 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c37530 b69a4058398fa3a81764767971281f27 398 Pfam PF02515 CoA-transferase family III 13 374 1.8E-111 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 MIM_c20210 e09647526ccd3ebf11a98ccb7232138d 461 Gene3D G3DSA:3.30.1330.120 271 405 5.9E-102 T 12-10-2018 MIM_c20210 e09647526ccd3ebf11a98ccb7232138d 461 SUPERFAMILY SSF103378 5 451 3.66E-99 T 12-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 MIM_c20210 e09647526ccd3ebf11a98ccb7232138d 461 Pfam PF03972 MmgE/PrpD family 10 425 1.7E-102 T 12-10-2018 IPR005656 MmgE/PrpD GO:0016829 MIM_c20210 e09647526ccd3ebf11a98ccb7232138d 461 Gene3D G3DSA:1.10.4100.10 27 421 5.9E-102 T 12-10-2018 MIM_c39980 b16b7a39cb9045ecf5c2554cc9971233 193 Pfam PF13618 Gluconate 2-dehydrogenase subunit 3 57 156 3.7E-8 T 12-10-2018 IPR027056 Gluconate 2-dehydrogenase subunit 3 KEGG: 00030+1.1.99.3|MetaCyc: PWY-7165 MIM_c39980 b16b7a39cb9045ecf5c2554cc9971233 193 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 16 48 6.1E-5 T 12-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal MIM_c16810 1de8891ac3fa6f416631351db4c9fca9 287 SMART SM00382 64 247 2.3E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c16810 1de8891ac3fa6f416631351db4c9fca9 287 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c16810 1de8891ac3fa6f416631351db4c9fca9 287 Gene3D G3DSA:3.40.50.300 33 270 1.2E-64 T 12-10-2018 MIM_c16810 1de8891ac3fa6f416631351db4c9fca9 287 SUPERFAMILY SSF52540 36 271 3.22E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c16810 1de8891ac3fa6f416631351db4c9fca9 287 Pfam PF00005 ABC transporter 55 197 1.4E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c14010 7debcc63db3a11abe54367b7b066c538 376 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 36 127 3.0E-22 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MIM_c14010 7debcc63db3a11abe54367b7b066c538 376 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 68 82 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MIM_c14010 7debcc63db3a11abe54367b7b066c538 376 Pfam PF00107 Zinc-binding dehydrogenase 204 329 7.5E-31 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MIM_c14010 7debcc63db3a11abe54367b7b066c538 376 SUPERFAMILY SSF51735 166 339 3.42E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c14010 7debcc63db3a11abe54367b7b066c538 376 Gene3D G3DSA:3.90.180.10 19 369 6.4E-117 T 12-10-2018 MIM_c14010 7debcc63db3a11abe54367b7b066c538 376 Gene3D G3DSA:3.40.50.720 181 317 6.4E-117 T 12-10-2018 MIM_c14010 7debcc63db3a11abe54367b7b066c538 376 SUPERFAMILY SSF50129 1 200 6.7E-56 T 12-10-2018 IPR011032 GroES-like superfamily MIM_c14010 7debcc63db3a11abe54367b7b066c538 376 SMART SM00829 21 373 2.1E-5 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MIM_c31140 11d1ab9be4f6ff9d86acb9361a2eb0ee 385 SUPERFAMILY SSF51905 5 372 3.37E-61 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c31140 11d1ab9be4f6ff9d86acb9361a2eb0ee 385 SUPERFAMILY SSF54373 177 277 5.3E-9 T 12-10-2018 MIM_c31140 11d1ab9be4f6ff9d86acb9361a2eb0ee 385 Pfam PF01494 FAD binding domain 5 347 1.2E-26 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 MIM_c31140 11d1ab9be4f6ff9d86acb9361a2eb0ee 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.9E-19 T 12-10-2018 MIM_c31140 11d1ab9be4f6ff9d86acb9361a2eb0ee 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 1.9E-19 T 12-10-2018 MIM_c31140 11d1ab9be4f6ff9d86acb9361a2eb0ee 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 336 352 1.9E-19 T 12-10-2018 MIM_c31140 11d1ab9be4f6ff9d86acb9361a2eb0ee 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 286 301 1.9E-19 T 12-10-2018 MIM_c31140 11d1ab9be4f6ff9d86acb9361a2eb0ee 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 317 1.9E-19 T 12-10-2018 MIM_c31140 11d1ab9be4f6ff9d86acb9361a2eb0ee 385 Gene3D G3DSA:3.50.50.60 6 382 7.2E-159 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c38380 277ab8bdf9b14fffffd33ef28d682b0a 353 SUPERFAMILY SSF51679 1 344 5.1E-66 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MIM_c38380 277ab8bdf9b14fffffd33ef28d682b0a 353 Gene3D G3DSA:3.20.20.30 1 346 1.3E-70 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MIM_c38380 277ab8bdf9b14fffffd33ef28d682b0a 353 Pfam PF00296 Luciferase-like monooxygenase 1 304 7.4E-50 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MIM_c23000 dcd2c2356c028cb1f4e1a291fdbde1b6 237 SMART SM00448 2 114 1.2E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c23000 dcd2c2356c028cb1f4e1a291fdbde1b6 237 Gene3D G3DSA:1.10.10.10 121 227 2.9E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c23000 dcd2c2356c028cb1f4e1a291fdbde1b6 237 Gene3D G3DSA:3.40.50.2300 2 120 4.7E-31 T 12-10-2018 MIM_c23000 dcd2c2356c028cb1f4e1a291fdbde1b6 237 SMART SM00862 148 223 9.3E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MIM_c23000 dcd2c2356c028cb1f4e1a291fdbde1b6 237 SUPERFAMILY SSF52172 1 181 5.17E-33 T 12-10-2018 IPR011006 CheY-like superfamily MIM_c23000 dcd2c2356c028cb1f4e1a291fdbde1b6 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 223 3.8E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MIM_c23000 dcd2c2356c028cb1f4e1a291fdbde1b6 237 Pfam PF00072 Response regulator receiver domain 5 115 3.2E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c06960 52a91393a02154f72751cd5a50ab7d3b 290 Pfam PF13622 Thioesterase-like superfamily 35 285 3.7E-56 T 12-10-2018 MIM_c06960 52a91393a02154f72751cd5a50ab7d3b 290 SUPERFAMILY SSF54637 6 117 2.06E-35 T 12-10-2018 IPR029069 HotDog domain superfamily MIM_c06960 52a91393a02154f72751cd5a50ab7d3b 290 Gene3D G3DSA:3.10.129.90 5 288 4.4E-101 T 12-10-2018 MIM_c06960 52a91393a02154f72751cd5a50ab7d3b 290 SUPERFAMILY SSF54637 120 287 1.97E-54 T 12-10-2018 IPR029069 HotDog domain superfamily MIM_c06220 fce56d22d90c8369549c36c3577f572f 436 SUPERFAMILY SSF50182 186 251 8.17E-12 T 12-10-2018 IPR010920 LSM domain superfamily MIM_c06220 fce56d22d90c8369549c36c3577f572f 436 Pfam PF00924 Mechanosensitive ion channel 143 396 1.8E-54 T 12-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MIM_c17140 75d548918592047ddb952eda8b40e9aa 189 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 40 133 2.1E-12 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MIM_c17140 75d548918592047ddb952eda8b40e9aa 189 Gene3D G3DSA:2.30.110.10 32 159 1.2E-19 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MIM_c17140 75d548918592047ddb952eda8b40e9aa 189 SUPERFAMILY SSF50475 39 142 6.62E-17 T 12-10-2018 MIM_c03390 d7a7c54ae50166092dc1423533757af9 407 Pfam PF02515 CoA-transferase family III 5 383 5.1E-130 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 MIM_c03390 d7a7c54ae50166092dc1423533757af9 407 Gene3D G3DSA:3.30.1540.10 243 334 3.2E-138 T 12-10-2018 MIM_c03390 d7a7c54ae50166092dc1423533757af9 407 Gene3D G3DSA:3.40.50.10540 5 401 3.2E-138 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c03390 d7a7c54ae50166092dc1423533757af9 407 SUPERFAMILY SSF89796 2 407 1.06E-138 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c07410 3b89d7f46ba3f954f6eacd9582d5cca5 550 SMART SM00245 193 398 8.8E-57 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 MIM_c07410 3b89d7f46ba3f954f6eacd9582d5cca5 550 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 73 401 4.9E-95 T 12-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 MIM_c07410 3b89d7f46ba3f954f6eacd9582d5cca5 550 SUPERFAMILY SSF52096 55 405 1.29E-74 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c07410 3b89d7f46ba3f954f6eacd9582d5cca5 550 SUPERFAMILY SSF50156 107 202 1.62E-18 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 MIM_c07410 3b89d7f46ba3f954f6eacd9582d5cca5 550 Gene3D G3DSA:3.90.226.10 208 395 9.9E-90 T 12-10-2018 MIM_c07410 3b89d7f46ba3f954f6eacd9582d5cca5 550 Pfam PF03572 Peptidase family S41 219 397 1.7E-52 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 MIM_c07410 3b89d7f46ba3f954f6eacd9582d5cca5 550 SMART SM00228 120 191 5.5E-17 T 12-10-2018 IPR001478 PDZ domain GO:0005515 MIM_c07410 3b89d7f46ba3f954f6eacd9582d5cca5 550 Pfam PF13180 PDZ domain 120 197 1.3E-10 T 12-10-2018 IPR001478 PDZ domain GO:0005515 MIM_c07410 3b89d7f46ba3f954f6eacd9582d5cca5 550 Gene3D G3DSA:2.30.42.10 120 207 9.9E-90 T 12-10-2018 MIM_c07410 3b89d7f46ba3f954f6eacd9582d5cca5 550 Gene3D G3DSA:3.30.750.44 68 373 9.9E-90 T 12-10-2018 MIM_c13890 c52cf2cfebf3339a7cf7915972a39498 377 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 68 82 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MIM_c13890 c52cf2cfebf3339a7cf7915972a39498 377 SUPERFAMILY SSF50129 17 200 6.09E-54 T 12-10-2018 IPR011032 GroES-like superfamily MIM_c13890 c52cf2cfebf3339a7cf7915972a39498 377 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 36 161 4.1E-24 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MIM_c13890 c52cf2cfebf3339a7cf7915972a39498 377 SMART SM00829 19 373 3.3E-4 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MIM_c13890 c52cf2cfebf3339a7cf7915972a39498 377 SUPERFAMILY SSF51735 166 340 2.22E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c13890 c52cf2cfebf3339a7cf7915972a39498 377 Gene3D G3DSA:3.40.50.720 181 317 1.1E-113 T 12-10-2018 MIM_c13890 c52cf2cfebf3339a7cf7915972a39498 377 Pfam PF00107 Zinc-binding dehydrogenase 204 321 6.1E-27 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MIM_c13890 c52cf2cfebf3339a7cf7915972a39498 377 Gene3D G3DSA:3.90.180.10 18 371 1.1E-113 T 12-10-2018 MIM_c11350 bfa62b8221ddceb84955864c6a3a2179 449 Gene3D G3DSA:1.10.287.130 205 286 2.4E-7 T 12-10-2018 MIM_c11350 bfa62b8221ddceb84955864c6a3a2179 449 SUPERFAMILY SSF47384 215 288 9.22E-7 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MIM_c11350 bfa62b8221ddceb84955864c6a3a2179 449 Gene3D G3DSA:3.30.565.10 287 438 4.7E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c11350 bfa62b8221ddceb84955864c6a3a2179 449 SMART SM00387 335 440 4.0E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c11350 bfa62b8221ddceb84955864c6a3a2179 449 SUPERFAMILY SSF55874 297 439 1.83E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c11350 bfa62b8221ddceb84955864c6a3a2179 449 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 338 438 2.9E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c39340 9983bf478929f31adeea6065a3135cc3 118 SUPERFAMILY SSF46785 9 95 4.82E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c39340 9983bf478929f31adeea6065a3135cc3 118 Gene3D G3DSA:1.10.10.10 3 115 1.7E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c39340 9983bf478929f31adeea6065a3135cc3 118 SMART SM00418 15 89 5.1E-13 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MIM_c39340 9983bf478929f31adeea6065a3135cc3 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 16 31 7.3E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MIM_c39340 9983bf478929f31adeea6065a3135cc3 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 7.3E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MIM_c39340 9983bf478929f31adeea6065a3135cc3 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 7.3E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MIM_c39340 9983bf478929f31adeea6065a3135cc3 118 Pfam PF12840 Helix-turn-helix domain 15 73 9.3E-10 T 12-10-2018 MIM_c23760 c515025efec49c0f8817022083e96202 230 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 22 222 1.1E-41 T 12-10-2018 IPR006214 Bax inhibitor 1-related MIM_c00840 c26b6f7afe8928d6bd8645b204b9693b 267 Pfam PF13432 Tetratricopeptide repeat 40 98 5.8E-8 T 12-10-2018 MIM_c00840 c26b6f7afe8928d6bd8645b204b9693b 267 Gene3D G3DSA:1.25.40.10 34 233 1.1E-24 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MIM_c00840 c26b6f7afe8928d6bd8645b204b9693b 267 SMART SM00028 131 164 15.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MIM_c00840 c26b6f7afe8928d6bd8645b204b9693b 267 SMART SM00028 64 97 0.14 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MIM_c00840 c26b6f7afe8928d6bd8645b204b9693b 267 SUPERFAMILY SSF48452 40 188 1.9E-19 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MIM_c09150 292bdf85b2f29195cee33a68340a21cc 63 Pfam PF11943 Protein of unknown function (DUF3460) 4 60 1.6E-26 T 12-10-2018 IPR021853 Protein of unknown function DUF3460 MIM_c11610 2b0f6670bb89aada59a34a758842a049 228 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c11610 2b0f6670bb89aada59a34a758842a049 228 Gene3D G3DSA:3.40.50.300 9 228 1.9E-55 T 12-10-2018 MIM_c11610 2b0f6670bb89aada59a34a758842a049 228 Pfam PF00005 ABC transporter 32 172 1.5E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c11610 2b0f6670bb89aada59a34a758842a049 228 SMART SM00382 30 221 3.6E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c11610 2b0f6670bb89aada59a34a758842a049 228 SUPERFAMILY SSF52540 13 226 3.12E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c06170 88e80c5100f6676b900174eddddc97e4 252 Pfam PF12706 Beta-lactamase superfamily domain 64 221 4.3E-16 T 12-10-2018 IPR001279 Metallo-beta-lactamase MIM_c06170 88e80c5100f6676b900174eddddc97e4 252 Gene3D G3DSA:3.60.15.10 1 252 2.1E-62 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MIM_c06170 88e80c5100f6676b900174eddddc97e4 252 SMART SM00849 37 192 0.0061 T 12-10-2018 IPR001279 Metallo-beta-lactamase MIM_c06170 88e80c5100f6676b900174eddddc97e4 252 SUPERFAMILY SSF56281 1 252 1.26E-35 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MIM_c06170 88e80c5100f6676b900174eddddc97e4 252 TIGRFAM TIGR03307 PhnP: phosphonate metabolism protein PhnP 1 248 9.9E-102 T 12-10-2018 IPR017693 Phosphonate metabolism protein PhnP GO:0008081|GO:0019700 KEGG: 00440+3.1.4.55|MetaCyc: PWY-7805|MetaCyc: PWY-7807 MIM_c26580 ff451a40b0da6767ad5ada20d2bca253 537 SUPERFAMILY SSF117457 349 519 1.7E-61 T 12-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 MIM_c26580 ff451a40b0da6767ad5ada20d2bca253 537 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 44 316 1.2E-62 T 12-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 MIM_c26580 ff451a40b0da6767ad5ada20d2bca253 537 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 358 519 1.8E-46 T 12-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 MIM_c26580 ff451a40b0da6767ad5ada20d2bca253 537 Gene3D G3DSA:3.20.130.10 334 520 2.1E-58 T 12-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 MIM_c26580 ff451a40b0da6767ad5ada20d2bca253 537 Pfam PF05681 Fumarate hydratase (Fumerase) 43 316 5.0E-99 T 12-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 MIM_c26580 ff451a40b0da6767ad5ada20d2bca253 537 Pfam PF05683 Fumarase C-terminus 320 521 1.0E-80 T 12-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 MIM_c26580 ff451a40b0da6767ad5ada20d2bca253 537 PIRSF PIRSF001394 29 537 1.4E-209 T 12-10-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 MIM_c15440 edad7588439ac96d30636a18c5cd13ac 274 PIRSF PIRSF012318 11 274 3.3E-97 T 12-10-2018 IPR011197 Uncharacterised conserved protein UCP012318 MIM_c15440 edad7588439ac96d30636a18c5cd13ac 274 SUPERFAMILY SSF47240 52 246 6.61E-15 T 12-10-2018 IPR009078 Ferritin-like superfamily MIM_c15440 edad7588439ac96d30636a18c5cd13ac 274 Pfam PF04305 Protein of unknown function (DUF455) 28 268 2.8E-94 T 12-10-2018 IPR007402 Protein of unknown function DUF455 MIM_c01520 004377bc76a8573ef042c112bcc6d55c 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 272 4.1E-29 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c01520 004377bc76a8573ef042c112bcc6d55c 281 Gene3D G3DSA:1.10.3720.10 79 274 1.2E-29 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c01520 004377bc76a8573ef042c112bcc6d55c 281 SUPERFAMILY SSF161098 79 260 3.92E-37 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c07330 a55a80531edfe1a850c39b47ec5cc7ec 269 SUPERFAMILY SSF53271 68 249 6.82E-23 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like MIM_c07330 a55a80531edfe1a850c39b47ec5cc7ec 269 Gene3D G3DSA:3.40.50.2020 141 261 2.3E-13 T 12-10-2018 MIM_c07330 a55a80531edfe1a850c39b47ec5cc7ec 269 Pfam PF00156 Phosphoribosyl transferase domain 212 247 2.5E-6 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MIM_c37170 8f441cfaba09b93fda8ec4d426319280 347 Gene3D G3DSA:3.40.718.10 1 332 1.8E-116 T 12-10-2018 MIM_c37170 8f441cfaba09b93fda8ec4d426319280 347 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 9 330 3.5E-98 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 MIM_c37170 8f441cfaba09b93fda8ec4d426319280 347 SUPERFAMILY SSF53659 7 330 1.25E-97 T 12-10-2018 MIM_c37170 8f441cfaba09b93fda8ec4d426319280 347 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 38 325 3.3E-93 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 MIM_c19940 1a05be29f6001e8b4a716c823c63e495 218 SUPERFAMILY SSF89562 12 182 1.31E-32 T 12-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily MIM_c19940 1a05be29f6001e8b4a716c823c63e495 218 Pfam PF03737 Aldolase/RraA 15 170 2.3E-28 T 12-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MIM_c19940 1a05be29f6001e8b4a716c823c63e495 218 Gene3D G3DSA:3.50.30.100 3 193 6.9E-42 T 12-10-2018 MIM_c27030 3d96644548e380ce2b6d232afb414628 223 Hamap MF_01385 Urease accessory protein UreF [ureF]. 3 223 18.005 T 12-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 MIM_c27030 3d96644548e380ce2b6d232afb414628 223 Gene3D G3DSA:1.10.4190.10 1 194 4.2E-29 T 12-10-2018 IPR038277 UreF domain superfamily MIM_c27030 3d96644548e380ce2b6d232afb414628 223 Pfam PF01730 UreF 36 176 9.8E-24 T 12-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 MIM_c27030 3d96644548e380ce2b6d232afb414628 223 PIRSF PIRSF009467 1 223 6.1E-41 T 12-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 MIM_c28950 d1f835d109d935c999a0cd3a42c8117b 204 Gene3D G3DSA:3.40.30.10 34 201 1.5E-50 T 12-10-2018 MIM_c28950 d1f835d109d935c999a0cd3a42c8117b 204 Pfam PF02630 SCO1/SenC 44 180 7.4E-40 T 12-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c28950 d1f835d109d935c999a0cd3a42c8117b 204 SUPERFAMILY SSF52833 46 200 1.55E-48 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c31040 5c07fc19103130b4aceeeea9831cfc5b 261 Pfam PF00753 Metallo-beta-lactamase superfamily 40 204 6.1E-19 T 12-10-2018 IPR001279 Metallo-beta-lactamase MIM_c31040 5c07fc19103130b4aceeeea9831cfc5b 261 SUPERFAMILY SSF56281 24 241 2.62E-35 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MIM_c31040 5c07fc19103130b4aceeeea9831cfc5b 261 Gene3D G3DSA:3.60.15.10 2 239 1.5E-52 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MIM_c31040 5c07fc19103130b4aceeeea9831cfc5b 261 SMART SM00849 36 236 1.1E-12 T 12-10-2018 IPR001279 Metallo-beta-lactamase MIM_c32280 b696fb75880e7e87fba667e55e4de6b8 913 Pfam PF05170 AsmA family 1 730 8.1E-44 T 12-10-2018 IPR007844 AsmA MIM_c37960 8057b3a17cdb518a31cf1df13a4c4ed1 435 Gene3D G3DSA:3.30.9.10 129 351 3.6E-47 T 12-10-2018 MIM_c37960 8057b3a17cdb518a31cf1df13a4c4ed1 435 Pfam PF01266 FAD dependent oxidoreductase 35 389 4.4E-32 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MIM_c37960 8057b3a17cdb518a31cf1df13a4c4ed1 435 Gene3D G3DSA:3.50.50.60 35 390 3.6E-47 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c37960 8057b3a17cdb518a31cf1df13a4c4ed1 435 SUPERFAMILY SSF51905 34 398 8.2E-31 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c05820 bbf21759f90064da51af90c37ed97675 400 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 138 364 4.6E-117 T 12-10-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 KEGG: 00190+2.7.4.1 MIM_c05820 bbf21759f90064da51af90c37ed97675 400 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 138 363 9.2E-107 T 12-10-2018 IPR022488 Polyphosphate kinase-2-related MIM_c05820 bbf21759f90064da51af90c37ed97675 400 Gene3D G3DSA:3.40.50.300 99 385 1.4E-104 T 12-10-2018 MIM_c05820 bbf21759f90064da51af90c37ed97675 400 SUPERFAMILY SSF52540 169 353 7.35E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c30860 5182ad162005c40cb0a205b1f44d063b 267 Pfam PF09859 Oxygenase, catalysing oxidative methylation of damaged DNA 76 247 9.5E-71 T 12-10-2018 IPR018655 Protein of unknown function DUF2086 MIM_c18820 81001227d9c9dedbf4f7e5efe73ef494 253 Gene3D G3DSA:3.20.20.190 6 249 2.3E-71 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 MIM_c18820 81001227d9c9dedbf4f7e5efe73ef494 253 SUPERFAMILY SSF51695 10 242 4.19E-61 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 MIM_c18820 81001227d9c9dedbf4f7e5efe73ef494 253 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 17 242 1.3E-34 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 MIM_c17370 c18e199b65f3f8b2817d6566468ce40e 498 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 439 7.2E-137 T 12-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane MIM_c04760 102fdba873fb21af33650fe2ce1c2edf 260 Pfam PF02405 Permease MlaE 44 255 1.4E-75 T 12-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 MIM_c04760 102fdba873fb21af33650fe2ce1c2edf 260 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 5 258 1.2E-80 T 12-10-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria MIM_c13590 b3f47b52d80c4896ffe9fcc8980c19dd 246 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 9 20 3.5E-9 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MIM_c13590 b3f47b52d80c4896ffe9fcc8980c19dd 246 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 151 167 3.5E-9 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MIM_c13590 b3f47b52d80c4896ffe9fcc8980c19dd 246 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 169 189 3.5E-9 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MIM_c13590 b3f47b52d80c4896ffe9fcc8980c19dd 246 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 196 209 3.5E-9 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MIM_c13590 b3f47b52d80c4896ffe9fcc8980c19dd 246 Pfam PF00702 haloacid dehalogenase-like hydrolase 11 198 3.0E-7 T 12-10-2018 MIM_c13590 b3f47b52d80c4896ffe9fcc8980c19dd 246 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 11 198 9.6E-20 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MIM_c13590 b3f47b52d80c4896ffe9fcc8980c19dd 246 Gene3D G3DSA:3.40.50.1000 10 231 9.3E-87 T 12-10-2018 IPR023214 HAD superfamily MIM_c13590 b3f47b52d80c4896ffe9fcc8980c19dd 246 Gene3D G3DSA:1.10.150.240 38 109 9.3E-87 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MIM_c13590 b3f47b52d80c4896ffe9fcc8980c19dd 246 SUPERFAMILY SSF56784 11 242 1.33E-41 T 12-10-2018 IPR036412 HAD-like superfamily MIM_c13590 b3f47b52d80c4896ffe9fcc8980c19dd 246 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 10 212 5.3E-48 T 12-10-2018 IPR006328 L-2-Haloacid dehalogenase GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 MIM_c18660 8ad16368b777c3d8ce34805214e6d08c 508 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 21 507 43.754 T 12-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MIM_c18660 8ad16368b777c3d8ce34805214e6d08c 508 PRINTS PR00982 Lysyl-tRNA synthetase signature 214 230 1.4E-39 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MIM_c18660 8ad16368b777c3d8ce34805214e6d08c 508 PRINTS PR00982 Lysyl-tRNA synthetase signature 243 256 1.4E-39 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MIM_c18660 8ad16368b777c3d8ce34805214e6d08c 508 PRINTS PR00982 Lysyl-tRNA synthetase signature 261 278 1.4E-39 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MIM_c18660 8ad16368b777c3d8ce34805214e6d08c 508 PRINTS PR00982 Lysyl-tRNA synthetase signature 198 208 1.4E-39 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MIM_c18660 8ad16368b777c3d8ce34805214e6d08c 508 PRINTS PR00982 Lysyl-tRNA synthetase signature 389 405 1.4E-39 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MIM_c18660 8ad16368b777c3d8ce34805214e6d08c 508 Pfam PF01336 OB-fold nucleic acid binding domain 69 145 6.0E-18 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MIM_c18660 8ad16368b777c3d8ce34805214e6d08c 508 Gene3D G3DSA:3.30.930.10 161 505 2.6E-128 T 12-10-2018 MIM_c18660 8ad16368b777c3d8ce34805214e6d08c 508 SUPERFAMILY SSF55681 161 505 9.57E-116 T 12-10-2018 MIM_c18660 8ad16368b777c3d8ce34805214e6d08c 508 Pfam PF00152 tRNA synthetases class II (D, K and N) 161 504 4.0E-84 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c18660 8ad16368b777c3d8ce34805214e6d08c 508 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 16 506 1.2E-193 T 12-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MIM_c18660 8ad16368b777c3d8ce34805214e6d08c 508 Gene3D G3DSA:2.40.50.140 15 153 3.1E-43 T 12-10-2018 MIM_c18660 8ad16368b777c3d8ce34805214e6d08c 508 SUPERFAMILY SSF50249 13 154 6.51E-44 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c37380 28094fd9b6c58e11b44e524299dba839 129 SUPERFAMILY SSF54593 2 123 5.1E-20 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c37380 28094fd9b6c58e11b44e524299dba839 129 Gene3D G3DSA:3.30.720.120 2 52 3.5E-16 T 12-10-2018 MIM_c37380 28094fd9b6c58e11b44e524299dba839 129 Gene3D G3DSA:3.30.720.110 70 124 2.8E-23 T 12-10-2018 MIM_c37380 28094fd9b6c58e11b44e524299dba839 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 117 1.8E-5 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MIM_c31600 e0c720749993cfb014d9ac90902bc2ae 138 Gene3D G3DSA:2.60.120.10 3 119 1.4E-10 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c31600 e0c720749993cfb014d9ac90902bc2ae 138 SUPERFAMILY SSF51182 19 100 1.51E-5 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c31750 10ce0f9314e2aca605f781bab2bd6071 269 Gene3D G3DSA:3.30.450.40 99 268 4.1E-31 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c31750 10ce0f9314e2aca605f781bab2bd6071 269 Pfam PF09339 IclR helix-turn-helix domain 24 73 7.7E-10 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c31750 10ce0f9314e2aca605f781bab2bd6071 269 SUPERFAMILY SSF46785 22 94 8.65E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c31750 10ce0f9314e2aca605f781bab2bd6071 269 Pfam PF01614 Bacterial transcriptional regulator 141 264 1.4E-16 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal MIM_c31750 10ce0f9314e2aca605f781bab2bd6071 269 SMART SM00346 22 113 7.7E-18 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c31750 10ce0f9314e2aca605f781bab2bd6071 269 Gene3D G3DSA:1.10.10.10 20 95 1.4E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c31750 10ce0f9314e2aca605f781bab2bd6071 269 SUPERFAMILY SSF55781 81 264 6.02E-32 T 12-10-2018 MIM_c17590 2374a60df1f63bcf58dcce7479ea2051 327 PIRSF PIRSF017082 5 327 4.3E-70 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c17590 2374a60df1f63bcf58dcce7479ea2051 327 Gene3D G3DSA:3.40.190.150 34 317 1.4E-86 T 12-10-2018 MIM_c17590 2374a60df1f63bcf58dcce7479ea2051 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 324 3.5E-61 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c17590 2374a60df1f63bcf58dcce7479ea2051 327 SUPERFAMILY SSF53850 113 291 1.68E-6 T 12-10-2018 MIM_c17590 2374a60df1f63bcf58dcce7479ea2051 327 Gene3D G3DSA:3.40.190.10 130 253 1.4E-86 T 12-10-2018 MIM_c05540 944b4df40bb8144e79dca994a7655c5e 106 SUPERFAMILY SSF69754 1 100 4.05E-32 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like MIM_c05540 944b4df40bb8144e79dca994a7655c5e 106 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 98 2.6E-29 T 12-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 MIM_c05540 944b4df40bb8144e79dca994a7655c5e 106 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 91 1.4E-25 T 12-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 MIM_c05540 944b4df40bb8144e79dca994a7655c5e 106 Gene3D G3DSA:3.30.160.100 1 105 1.2E-33 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like MIM_c20820 46c18cc0b257b7617406bdb9832f1809 324 Gene3D G3DSA:3.40.190.150 30 313 5.4E-92 T 12-10-2018 MIM_c20820 46c18cc0b257b7617406bdb9832f1809 324 Gene3D G3DSA:3.40.190.10 127 249 5.4E-92 T 12-10-2018 MIM_c20820 46c18cc0b257b7617406bdb9832f1809 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 320 3.0E-64 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c20820 46c18cc0b257b7617406bdb9832f1809 324 SUPERFAMILY SSF53850 120 282 4.56E-12 T 12-10-2018 MIM_c20820 46c18cc0b257b7617406bdb9832f1809 324 PIRSF PIRSF017082 1 324 1.0E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c33400 55977ecd5cbbb5bb50fa62fb6c0ea8a6 155 Gene3D G3DSA:3.40.630.30 1 151 2.9E-23 T 12-10-2018 MIM_c33400 55977ecd5cbbb5bb50fa62fb6c0ea8a6 155 SUPERFAMILY SSF55729 6 148 3.31E-23 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c33400 55977ecd5cbbb5bb50fa62fb6c0ea8a6 155 Pfam PF13673 Acetyltransferase (GNAT) domain 48 150 2.3E-10 T 12-10-2018 IPR000182 GNAT domain MIM_c01030 2fa21fa0af1e323d9992ef078a449742 389 PIRSF PIRSF000429 1 385 6.5E-59 T 12-10-2018 IPR002155 Thiolase GO:0016747 MIM_c01030 2fa21fa0af1e323d9992ef078a449742 389 Pfam PF02803 Thiolase, C-terminal domain 246 366 7.8E-11 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 MIM_c01030 2fa21fa0af1e323d9992ef078a449742 389 Gene3D G3DSA:3.40.47.10 1 389 2.8E-93 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c01030 2fa21fa0af1e323d9992ef078a449742 389 Pfam PF00108 Thiolase, N-terminal domain 15 227 1.1E-19 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 MIM_c01030 2fa21fa0af1e323d9992ef078a449742 389 SUPERFAMILY SSF53901 22 359 2.58E-36 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c12480 1d95a4f84bc8b5fa364ce716bacce255 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 319 7.3E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c12480 1d95a4f84bc8b5fa364ce716bacce255 324 Gene3D G3DSA:3.40.190.10 125 248 9.4E-103 T 12-10-2018 MIM_c12480 1d95a4f84bc8b5fa364ce716bacce255 324 SUPERFAMILY SSF53850 97 286 1.02E-9 T 12-10-2018 MIM_c12480 1d95a4f84bc8b5fa364ce716bacce255 324 PIRSF PIRSF017082 2 323 9.9E-78 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c12480 1d95a4f84bc8b5fa364ce716bacce255 324 Gene3D G3DSA:3.40.190.150 27 313 9.4E-103 T 12-10-2018 MIM_c15580 0452dfb53a8c958d4f65cc673b1856d6 255 Pfam PF01925 Sulfite exporter TauE/SafE 13 247 6.9E-38 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MIM_c36750 5e1efba91e92063f1416531965a39bf5 327 PIRSF PIRSF017082 5 326 1.5E-85 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c36750 5e1efba91e92063f1416531965a39bf5 327 SUPERFAMILY SSF53850 117 289 3.41E-14 T 12-10-2018 MIM_c36750 5e1efba91e92063f1416531965a39bf5 327 Gene3D G3DSA:3.40.190.10 129 252 1.9E-107 T 12-10-2018 MIM_c36750 5e1efba91e92063f1416531965a39bf5 327 Gene3D G3DSA:3.40.190.150 32 317 1.9E-107 T 12-10-2018 MIM_c36750 5e1efba91e92063f1416531965a39bf5 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 323 2.6E-78 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c35950 8f927e73f67ba68a569a252e92559de1 266 Gene3D G3DSA:1.10.3720.10 10 264 1.3E-44 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c35950 8f927e73f67ba68a569a252e92559de1 266 SUPERFAMILY SSF161098 10 255 1.03E-43 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c35950 8f927e73f67ba68a569a252e92559de1 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 261 3.5E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c01370 8ca8313b2a3c5ef9ffda388352de4d9d 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 5.9E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01370 8ca8313b2a3c5ef9ffda388352de4d9d 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 5.9E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01370 8ca8313b2a3c5ef9ffda388352de4d9d 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 5.9E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01370 8ca8313b2a3c5ef9ffda388352de4d9d 268 SUPERFAMILY SSF51735 9 249 5.84E-62 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c01370 8ca8313b2a3c5ef9ffda388352de4d9d 268 Gene3D G3DSA:3.40.50.720 2 266 2.3E-68 T 12-10-2018 MIM_c01370 8ca8313b2a3c5ef9ffda388352de4d9d 268 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 247 4.1E-52 T 12-10-2018 MIM_c01370 8ca8313b2a3c5ef9ffda388352de4d9d 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.1E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01370 8ca8313b2a3c5ef9ffda388352de4d9d 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 1.1E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01370 8ca8313b2a3c5ef9ffda388352de4d9d 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.1E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01370 8ca8313b2a3c5ef9ffda388352de4d9d 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.1E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01370 8ca8313b2a3c5ef9ffda388352de4d9d 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.1E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01370 8ca8313b2a3c5ef9ffda388352de4d9d 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.1E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c11440 1b07cf4e57cb67700b4b506f2dc848db 307 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 10 279 1.1E-40 T 12-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system MIM_c30900 4840d505d11c71184433916c1892c9fb 330 Gene3D G3DSA:3.40.190.150 34 320 1.8E-117 T 12-10-2018 MIM_c30900 4840d505d11c71184433916c1892c9fb 330 PIRSF PIRSF017082 1 330 1.9E-88 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c30900 4840d505d11c71184433916c1892c9fb 330 SUPERFAMILY SSF53850 98 290 1.76E-11 T 12-10-2018 MIM_c30900 4840d505d11c71184433916c1892c9fb 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 326 7.9E-96 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c30900 4840d505d11c71184433916c1892c9fb 330 Gene3D G3DSA:3.40.190.10 131 255 1.8E-117 T 12-10-2018 MIM_c34590 d227ad761d3f3d872fbebc51a05ae9fd 386 SUPERFAMILY SSF53850 30 348 4.21E-30 T 12-10-2018 MIM_c34590 d227ad761d3f3d872fbebc51a05ae9fd 386 Pfam PF13416 Bacterial extracellular solute-binding protein 48 340 1.4E-30 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein MIM_c34590 d227ad761d3f3d872fbebc51a05ae9fd 386 Gene3D G3DSA:3.40.190.10 13 152 3.8E-5 T 12-10-2018 MIM_c34590 d227ad761d3f3d872fbebc51a05ae9fd 386 Gene3D G3DSA:3.40.190.10 153 317 1.3E-11 T 12-10-2018 MIM_c18180 db8a6ddc9bd2b347d6426c827630df44 399 PRINTS PR00799 Aspartate aminotransferase signature 178 197 1.9E-39 T 12-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 MIM_c18180 db8a6ddc9bd2b347d6426c827630df44 399 PRINTS PR00799 Aspartate aminotransferase signature 344 362 1.9E-39 T 12-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 MIM_c18180 db8a6ddc9bd2b347d6426c827630df44 399 PRINTS PR00799 Aspartate aminotransferase signature 276 301 1.9E-39 T 12-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 MIM_c18180 db8a6ddc9bd2b347d6426c827630df44 399 PRINTS PR00799 Aspartate aminotransferase signature 209 221 1.9E-39 T 12-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 MIM_c18180 db8a6ddc9bd2b347d6426c827630df44 399 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 246 259 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 MIM_c18180 db8a6ddc9bd2b347d6426c827630df44 399 Pfam PF00155 Aminotransferase class I and II 30 395 8.6E-86 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MIM_c18180 db8a6ddc9bd2b347d6426c827630df44 399 Gene3D G3DSA:3.40.640.10 63 303 7.7E-170 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c18180 db8a6ddc9bd2b347d6426c827630df44 399 Gene3D G3DSA:3.90.1150.10 8 395 7.7E-170 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c18180 db8a6ddc9bd2b347d6426c827630df44 399 SUPERFAMILY SSF53383 1 398 9.39E-122 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c01340 434ab2942e32ef5a16c4e90e47c5c48e 313 PIRSF PIRSF019423 4 313 2.0E-121 T 12-10-2018 IPR011213 Nicotinic acid mononucleotide biosynthesis protein MIM_c01340 434ab2942e32ef5a16c4e90e47c5c48e 313 Gene3D G3DSA:1.10.10.10 225 301 1.3E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c01340 434ab2942e32ef5a16c4e90e47c5c48e 313 SUPERFAMILY SSF55811 39 144 1.87E-6 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MIM_c01340 434ab2942e32ef5a16c4e90e47c5c48e 313 SUPERFAMILY SSF46785 232 303 7.89E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c29680 bb9fd317c6ebafc157d354d91a83a79a 141 SUPERFAMILY SSF47413 21 86 6.97E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c29680 bb9fd317c6ebafc157d354d91a83a79a 141 SMART SM00530 25 83 1.0E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c29680 bb9fd317c6ebafc157d354d91a83a79a 141 Gene3D G3DSA:1.10.260.40 7 86 9.2E-16 T 12-10-2018 MIM_c29680 bb9fd317c6ebafc157d354d91a83a79a 141 Pfam PF01381 Helix-turn-helix 29 83 2.6E-12 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c40930 2f9a7568125836eefb42dff495be5da6 415 Gene3D G3DSA:3.50.50.60 101 395 2.0E-40 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c40930 2f9a7568125836eefb42dff495be5da6 415 Gene3D G3DSA:3.50.50.60 1 70 1.2E-12 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c40930 2f9a7568125836eefb42dff495be5da6 415 SUPERFAMILY SSF51905 3 413 1.13E-45 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c40930 2f9a7568125836eefb42dff495be5da6 415 Pfam PF01266 FAD dependent oxidoreductase 4 394 3.6E-55 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MIM_c40930 2f9a7568125836eefb42dff495be5da6 415 Gene3D G3DSA:3.30.9.10 135 354 2.0E-40 T 12-10-2018 MIM_c40930 2f9a7568125836eefb42dff495be5da6 415 SUPERFAMILY SSF54373 270 355 7.06E-6 T 12-10-2018 MIM_c35100 e843c955a32086399775943ef83774ba 806 SUPERFAMILY SSF69255 387 474 6.02E-31 T 12-10-2018 MIM_c35100 e843c955a32086399775943ef83774ba 806 SUPERFAMILY SSF69279 183 385 4.08E-33 T 12-10-2018 MIM_c35100 e843c955a32086399775943ef83774ba 806 SUPERFAMILY SSF69349 465 705 2.43E-28 T 12-10-2018 MIM_c35100 e843c955a32086399775943ef83774ba 806 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 17 527 1.4E-137 T 12-10-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein MIM_c35100 e843c955a32086399775943ef83774ba 806 SUPERFAMILY SSF69279 5 178 1.45E-53 T 12-10-2018 MIM_c35100 e843c955a32086399775943ef83774ba 806 Gene3D G3DSA:3.30.1920.30 219 282 1.8E-109 T 12-10-2018 MIM_c35100 e843c955a32086399775943ef83774ba 806 Gene3D G3DSA:2.30.110.50 11 328 1.8E-109 T 12-10-2018 MIM_c35100 e843c955a32086399775943ef83774ba 806 Pfam PF05954 Phage late control gene D protein (GPD) 22 325 9.1E-95 T 12-10-2018 MIM_c35100 e843c955a32086399775943ef83774ba 806 Gene3D G3DSA:3.55.50.10 93 183 1.8E-109 T 12-10-2018 MIM_c35100 e843c955a32086399775943ef83774ba 806 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 9 542 3.3E-171 T 12-10-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset MIM_c35100 e843c955a32086399775943ef83774ba 806 Gene3D G3DSA:2.40.50.230 377 479 1.4E-41 T 12-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily MIM_c12590 b656cb90e45d176a1dcfeee0d515a461 207 Gene3D G3DSA:1.10.340.30 44 155 3.2E-58 T 12-10-2018 MIM_c12590 b656cb90e45d176a1dcfeee0d515a461 207 Gene3D G3DSA:1.10.1670.40 20 205 3.2E-58 T 12-10-2018 MIM_c12590 b656cb90e45d176a1dcfeee0d515a461 207 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 52 192 6.7E-12 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MIM_c12590 b656cb90e45d176a1dcfeee0d515a461 207 SUPERFAMILY SSF48150 37 206 5.58E-40 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MIM_c12590 b656cb90e45d176a1dcfeee0d515a461 207 SMART SM00478 55 207 3.2E-14 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MIM_c12240 9e6dd7c26f97db617131d58949eed333 484 SMART SM00155 219 246 13.0 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MIM_c12240 9e6dd7c26f97db617131d58949eed333 484 SMART SM00155 397 424 4.0E-5 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MIM_c12240 9e6dd7c26f97db617131d58949eed333 484 SUPERFAMILY SSF56024 271 467 6.28E-41 T 12-10-2018 MIM_c12240 9e6dd7c26f97db617131d58949eed333 484 Pfam PF13091 PLD-like domain 137 247 7.5E-15 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MIM_c12240 9e6dd7c26f97db617131d58949eed333 484 Pfam PF13091 PLD-like domain 329 445 6.4E-25 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MIM_c12240 9e6dd7c26f97db617131d58949eed333 484 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 19 483 9.6E-88 T 12-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 MIM_c12240 9e6dd7c26f97db617131d58949eed333 484 Gene3D G3DSA:3.30.870.10 307 476 5.6E-25 T 12-10-2018 MIM_c12240 9e6dd7c26f97db617131d58949eed333 484 Gene3D G3DSA:3.30.870.10 114 306 3.3E-40 T 12-10-2018 MIM_c12240 9e6dd7c26f97db617131d58949eed333 484 PIRSF PIRSF000850 369 454 8.8E-5 T 12-10-2018 MIM_c12240 9e6dd7c26f97db617131d58949eed333 484 PIRSF PIRSF000850 122 186 220.0 T 12-10-2018 MIM_c12240 9e6dd7c26f97db617131d58949eed333 484 PIRSF PIRSF000850 309 372 0.035 T 12-10-2018 MIM_c12240 9e6dd7c26f97db617131d58949eed333 484 Pfam PF13396 Phospholipase_D-nuclease N-terminal 22 63 6.0E-10 T 12-10-2018 IPR027379 Cardiolipin synthase N-terminal MIM_c12240 9e6dd7c26f97db617131d58949eed333 484 SUPERFAMILY SSF56024 96 315 2.69E-47 T 12-10-2018 MIM_c20920 f21e3cd074f7423657a411c08c4fc8ff 393 Gene3D G3DSA:1.20.1090.10 197 393 6.0E-32 T 12-10-2018 MIM_c20920 f21e3cd074f7423657a411c08c4fc8ff 393 SUPERFAMILY SSF56796 16 389 1.83E-61 T 12-10-2018 MIM_c20920 f21e3cd074f7423657a411c08c4fc8ff 393 Gene3D G3DSA:3.40.50.1970 6 195 2.4E-28 T 12-10-2018 MIM_c20920 f21e3cd074f7423657a411c08c4fc8ff 393 Pfam PF00465 Iron-containing alcohol dehydrogenase 16 383 2.2E-63 T 12-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 MIM_c21020 605d3bdc69ce87ced696095024d6bbeb 187 SUPERFAMILY SSF52499 3 180 3.01E-42 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MIM_c21020 605d3bdc69ce87ced696095024d6bbeb 187 Gene3D G3DSA:3.40.50.850 1 184 8.6E-52 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MIM_c21020 605d3bdc69ce87ced696095024d6bbeb 187 Pfam PF00857 Isochorismatase family 9 157 2.4E-27 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 MIM_c32870 ff07c319c198a4d99310858bf0b231c7 428 Pfam PF01547 Bacterial extracellular solute-binding protein 42 337 1.2E-31 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein MIM_c32870 ff07c319c198a4d99310858bf0b231c7 428 Gene3D G3DSA:3.40.190.10 150 420 4.7E-77 T 12-10-2018 MIM_c32870 ff07c319c198a4d99310858bf0b231c7 428 SUPERFAMILY SSF53850 35 422 1.8E-62 T 12-10-2018 MIM_c32870 ff07c319c198a4d99310858bf0b231c7 428 Gene3D G3DSA:3.40.190.10 41 383 4.7E-77 T 12-10-2018 MIM_c18520 77a788a9a57affb85c79465d15e3df3c 167 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 137 1.7E-41 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type MIM_c18520 77a788a9a57affb85c79465d15e3df3c 167 Pfam PF02082 Transcriptional regulator 1 83 5.7E-28 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type MIM_c18520 77a788a9a57affb85c79465d15e3df3c 167 SUPERFAMILY SSF46785 2 138 5.51E-36 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c18520 77a788a9a57affb85c79465d15e3df3c 167 Gene3D G3DSA:1.10.10.10 1 150 3.3E-50 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c30650 8e3e9f8a0c4988ec2a268e2c7636cdbc 135 Gene3D G3DSA:3.30.1460.30 4 113 2.2E-29 T 12-10-2018 MIM_c30650 8e3e9f8a0c4988ec2a268e2c7636cdbc 135 Pfam PF04993 TfoX N-terminal domain 13 111 5.5E-30 T 12-10-2018 IPR007076 TfoX, N-terminal MIM_c30650 8e3e9f8a0c4988ec2a268e2c7636cdbc 135 SUPERFAMILY SSF159894 6 111 4.71E-27 T 12-10-2018 MIM_c05320 9249147ee5ecbc0a32fde96d8728da2a 546 SMART SM00490 259 340 5.0E-31 T 12-10-2018 IPR001650 Helicase, C-terminal MIM_c05320 9249147ee5ecbc0a32fde96d8728da2a 546 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 153 161 - T 12-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MIM_c05320 9249147ee5ecbc0a32fde96d8728da2a 546 Gene3D G3DSA:3.40.50.300 1 211 3.0E-78 T 12-10-2018 MIM_c05320 9249147ee5ecbc0a32fde96d8728da2a 546 Pfam PF00271 Helicase conserved C-terminal domain 232 340 1.5E-26 T 12-10-2018 IPR001650 Helicase, C-terminal MIM_c05320 9249147ee5ecbc0a32fde96d8728da2a 546 Gene3D G3DSA:3.40.50.300 213 383 1.5E-49 T 12-10-2018 MIM_c05320 9249147ee5ecbc0a32fde96d8728da2a 546 SMART SM00487 20 222 4.5E-59 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MIM_c05320 9249147ee5ecbc0a32fde96d8728da2a 546 Pfam PF00270 DEAD/DEAH box helicase 25 193 1.3E-49 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MIM_c05320 9249147ee5ecbc0a32fde96d8728da2a 546 SUPERFAMILY SSF52540 73 362 1.66E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c35010 dd8328b272c6eeb97bf473e836460a2f 285 Pfam PF02653 Branched-chain amino acid transport system / permease component 3 269 8.5E-37 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c33170 25ba0cb41cee85160c75e0737b3162e9 283 Pfam PF01578 Cytochrome C assembly protein 65 274 4.5E-20 T 12-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 MIM_c38310 dddd8343fdc62dffa57f9c41a7fa302a 423 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 1.6E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38310 dddd8343fdc62dffa57f9c41a7fa302a 423 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 1.6E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38310 dddd8343fdc62dffa57f9c41a7fa302a 423 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 1.6E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38310 dddd8343fdc62dffa57f9c41a7fa302a 423 Gene3D G3DSA:3.40.50.720 6 257 1.1E-56 T 12-10-2018 MIM_c38310 dddd8343fdc62dffa57f9c41a7fa302a 423 Gene3D G3DSA:3.40.50.720 274 423 1.2E-6 T 12-10-2018 MIM_c38310 dddd8343fdc62dffa57f9c41a7fa302a 423 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 250 1.8E-38 T 12-10-2018 MIM_c38310 dddd8343fdc62dffa57f9c41a7fa302a 423 SUPERFAMILY SSF51735 10 252 5.68E-55 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c38310 dddd8343fdc62dffa57f9c41a7fa302a 423 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 6.2E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38310 dddd8343fdc62dffa57f9c41a7fa302a 423 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 6.2E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38310 dddd8343fdc62dffa57f9c41a7fa302a 423 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 6.2E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38310 dddd8343fdc62dffa57f9c41a7fa302a 423 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 6.2E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38310 dddd8343fdc62dffa57f9c41a7fa302a 423 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 6.2E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38310 dddd8343fdc62dffa57f9c41a7fa302a 423 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 6.2E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c29090 256c246f3d497606d0f80382d3089d29 168 SUPERFAMILY SSF52788 6 144 6.54E-40 T 12-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily MIM_c29090 256c246f3d497606d0f80382d3089d29 168 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 8 140 5.1E-15 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I MIM_c29090 256c246f3d497606d0f80382d3089d29 168 Gene3D G3DSA:3.40.50.2300 4 144 8.3E-40 T 12-10-2018 MIM_c29090 256c246f3d497606d0f80382d3089d29 168 SMART SM00226 6 144 7.8E-32 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I MIM_c14610 1f953d78f1b46dba41ccac4adf60bcbe 307 Gene3D G3DSA:1.10.287.480 189 236 3.6E-10 T 12-10-2018 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain superfamily MIM_c14610 1f953d78f1b46dba41ccac4adf60bcbe 307 SUPERFAMILY SSF64397 4 243 1.31E-61 T 12-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 MIM_c14610 1f953d78f1b46dba41ccac4adf60bcbe 307 PIRSF PIRSF005261 1 295 2.2E-75 T 12-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 MIM_c14610 1f953d78f1b46dba41ccac4adf60bcbe 307 SUPERFAMILY SSF118352 235 292 1.44E-17 T 12-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 MIM_c14610 1f953d78f1b46dba41ccac4adf60bcbe 307 Gene3D G3DSA:3.90.1280.10 237 294 2.5E-19 T 12-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 MIM_c14610 1f953d78f1b46dba41ccac4adf60bcbe 307 Gene3D G3DSA:3.55.30.10 1 180 1.2E-56 T 12-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 MIM_c14610 1f953d78f1b46dba41ccac4adf60bcbe 307 Pfam PF01430 Hsp33 protein 4 284 4.6E-82 T 12-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 MIM_c16290 1f5b2048a6ca4e7a079917adf47ebaa8 281 Gene3D G3DSA:1.20.81.30 107 216 1.8E-9 T 12-10-2018 MIM_c16290 1f5b2048a6ca4e7a079917adf47ebaa8 281 Pfam PF00482 Type II secretion system (T2SS), protein F 115 238 2.5E-17 T 12-10-2018 IPR018076 Type II secretion system F domain MIM_c13540 b916c9a7a43270d94af061221851ef09 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 188 3.1E-4 T 12-10-2018 MIM_c13540 b916c9a7a43270d94af061221851ef09 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 4.0E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c13540 b916c9a7a43270d94af061221851ef09 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 4.0E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c13540 b916c9a7a43270d94af061221851ef09 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 4.0E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c13540 b916c9a7a43270d94af061221851ef09 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 4.0E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c13540 b916c9a7a43270d94af061221851ef09 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 4.0E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c13540 b916c9a7a43270d94af061221851ef09 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 4.0E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c13540 b916c9a7a43270d94af061221851ef09 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.7E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c13540 b916c9a7a43270d94af061221851ef09 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 2.7E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c13540 b916c9a7a43270d94af061221851ef09 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 2.7E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c13540 b916c9a7a43270d94af061221851ef09 245 Pfam PF00106 short chain dehydrogenase 4 195 1.2E-62 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c13540 b916c9a7a43270d94af061221851ef09 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c13540 b916c9a7a43270d94af061221851ef09 245 SUPERFAMILY SSF51735 3 244 3.3E-81 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c13540 b916c9a7a43270d94af061221851ef09 245 Gene3D G3DSA:3.40.50.720 1 245 1.1E-82 T 12-10-2018 MIM_c13540 b916c9a7a43270d94af061221851ef09 245 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 4 244 8.0E-117 T 12-10-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216|MetaCyc: PWY-7948 MIM_c32370 0de10b964512af25c6130641794fa0c3 757 Gene3D G3DSA:2.40.170.20 194 757 2.6E-80 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MIM_c32370 0de10b964512af25c6130641794fa0c3 757 Pfam PF00593 TonB dependent receptor 256 756 1.6E-28 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MIM_c32370 0de10b964512af25c6130641794fa0c3 757 SUPERFAMILY SSF56935 52 756 4.03E-55 T 12-10-2018 MIM_c32370 0de10b964512af25c6130641794fa0c3 757 Gene3D G3DSA:2.170.130.10 56 193 4.8E-36 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MIM_c32370 0de10b964512af25c6130641794fa0c3 757 Pfam PF07715 TonB-dependent Receptor Plug Domain 60 177 4.0E-6 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain MIM_c00180 b6145826b4c778ac53c0f1cf23d81bc8 310 SUPERFAMILY SSF53850 93 299 3.26E-42 T 12-10-2018 MIM_c00180 b6145826b4c778ac53c0f1cf23d81bc8 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 6.0E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c00180 b6145826b4c778ac53c0f1cf23d81bc8 310 Pfam PF03466 LysR substrate binding domain 92 294 8.0E-40 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c00180 b6145826b4c778ac53c0f1cf23d81bc8 310 SUPERFAMILY SSF46785 6 114 7.71E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c00180 b6145826b4c778ac53c0f1cf23d81bc8 310 Gene3D G3DSA:1.10.10.10 5 91 2.1E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c00180 b6145826b4c778ac53c0f1cf23d81bc8 310 Gene3D G3DSA:3.40.190.10 93 292 3.7E-55 T 12-10-2018 MIM_c00180 b6145826b4c778ac53c0f1cf23d81bc8 310 Gene3D G3DSA:3.40.190.10 165 267 3.7E-55 T 12-10-2018 MIM_c34280 23392f11b9c591c10883d8d63773f512 300 Pfam PF12183 Restriction endonuclease NotI 7 251 3.2E-45 T 12-10-2018 IPR022009 Restriction endonuclease, type II, NotI MIM_c25220 29787c062124849e678ffe1b600c314a 414 SUPERFAMILY SSF51395 35 408 1.59E-86 T 12-10-2018 MIM_c25220 29787c062124849e678ffe1b600c314a 414 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 307 313 - T 12-10-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Reactome: R-HSA-9033241 MIM_c25220 29787c062124849e678ffe1b600c314a 414 PIRSF PIRSF000138 15 414 9.4E-123 T 12-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 MIM_c25220 29787c062124849e678ffe1b600c314a 414 Gene3D G3DSA:3.20.20.70 34 412 4.2E-118 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c25220 29787c062124849e678ffe1b600c314a 414 Pfam PF01070 FMN-dependent dehydrogenase 45 409 3.9E-121 T 12-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 MIM_c27180 562a6e3eee59d409dbf703a1db236f95 553 Gene3D G3DSA:3.90.226.10 6 553 2.4E-295 T 12-10-2018 MIM_c27180 562a6e3eee59d409dbf703a1db236f95 553 Pfam PF00378 Enoyl-CoA hydratase/isomerase 47 237 2.1E-24 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c27180 562a6e3eee59d409dbf703a1db236f95 553 Gene3D G3DSA:3.90.226.10 259 488 2.4E-295 T 12-10-2018 MIM_c27180 562a6e3eee59d409dbf703a1db236f95 553 SUPERFAMILY SSF52096 13 234 6.17E-32 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c27180 562a6e3eee59d409dbf703a1db236f95 553 TIGRFAM TIGR03222 benzo_boxC: benzoyl-CoA-dihydrodiol lyase 6 553 6.6E-279 T 12-10-2018 IPR017633 Benzoyl-CoA-dihydrodiol lyase KEGG: 00362+4.1.2.44|MetaCyc: PWY-1361 MIM_c27180 562a6e3eee59d409dbf703a1db236f95 553 SUPERFAMILY SSF52096 298 547 4.77E-16 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c30640 7ee2c89b77f499720b39e2cde7a9aba4 294 Gene3D G3DSA:3.40.50.300 53 294 2.4E-69 T 12-10-2018 MIM_c30640 7ee2c89b77f499720b39e2cde7a9aba4 294 Pfam PF00005 ABC transporter 66 214 3.5E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c30640 7ee2c89b77f499720b39e2cde7a9aba4 294 ProSitePatterns PS00211 ABC transporters family signature. 187 201 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c30640 7ee2c89b77f499720b39e2cde7a9aba4 294 SMART SM00382 75 263 1.3E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c30640 7ee2c89b77f499720b39e2cde7a9aba4 294 SUPERFAMILY SSF52540 60 289 1.77E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c17870 fb513e695380ccf888518e41f3ee0b1c 174 SUPERFAMILY SSF47413 20 59 8.44E-5 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c17870 fb513e695380ccf888518e41f3ee0b1c 174 Gene3D G3DSA:1.10.260.40 12 121 8.1E-20 T 12-10-2018 MIM_c17870 fb513e695380ccf888518e41f3ee0b1c 174 Pfam PF13413 Helix-turn-helix domain 26 85 8.8E-16 T 12-10-2018 MIM_c15390 226ca64f4b571dd01ddc0c562e41424b 321 Pfam PF01757 Acyltransferase family 6 311 1.4E-19 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 MIM_c15300 ec0010a80d4d5f3e0cc4e1f9c0d5882a 340 SUPERFAMILY SSF53474 63 335 1.19E-38 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c15300 ec0010a80d4d5f3e0cc4e1f9c0d5882a 340 Gene3D G3DSA:3.40.50.1820 46 340 5.9E-60 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c15300 ec0010a80d4d5f3e0cc4e1f9c0d5882a 340 Pfam PF00756 Putative esterase 67 293 2.1E-12 T 12-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 MIM_c09790 2a5806f6ee6b1ea046288b793da893d2 269 Pfam PF08478 POTRA domain, FtsQ-type 53 111 5.8E-12 T 12-10-2018 IPR013685 POTRA domain, FtsQ-type MIM_c09790 2a5806f6ee6b1ea046288b793da893d2 269 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 8 254 21.683 T 12-10-2018 IPR026579 Cell division protein FtsQ GO:0090529 MIM_c09790 2a5806f6ee6b1ea046288b793da893d2 269 Gene3D G3DSA:3.40.50.11690 113 260 5.9E-39 T 12-10-2018 MIM_c09790 2a5806f6ee6b1ea046288b793da893d2 269 Pfam PF03799 Cell division protein FtsQ 115 246 3.5E-23 T 12-10-2018 IPR005548 Cell division protein FtsQ/DivIB MIM_c09790 2a5806f6ee6b1ea046288b793da893d2 269 Gene3D G3DSA:3.10.20.310 39 111 2.1E-13 T 12-10-2018 MIM_c33920 ac8f8c33292c95efcb111ad4742196af 465 Pfam PF00296 Luciferase-like monooxygenase 28 384 1.2E-53 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MIM_c33920 ac8f8c33292c95efcb111ad4742196af 465 SUPERFAMILY SSF51679 4 436 9.68E-107 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MIM_c33920 ac8f8c33292c95efcb111ad4742196af 465 PIRSF PIRSF000337 2 447 1.6E-134 T 12-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MIM_c33920 ac8f8c33292c95efcb111ad4742196af 465 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 11 432 1.0E-131 T 12-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MIM_c05340 1e7eb83a16e835d9d8469eed6e27d724 264 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 56 74 - T 12-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 MIM_c05340 1e7eb83a16e835d9d8469eed6e27d724 264 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 262 35.588 T 12-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 MIM_c05340 1e7eb83a16e835d9d8469eed6e27d724 264 Gene3D G3DSA:3.20.20.70 1 263 6.0E-103 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c05340 1e7eb83a16e835d9d8469eed6e27d724 264 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 254 2.7E-97 T 12-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 MIM_c05340 1e7eb83a16e835d9d8469eed6e27d724 264 SUPERFAMILY SSF51366 12 261 2.12E-88 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MIM_c23180 45da576eeb9cfd7535dccb966b908200 408 Gene3D G3DSA:1.10.1060.10 7 109 1.6E-9 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MIM_c23180 45da576eeb9cfd7535dccb966b908200 408 SUPERFAMILY SSF54862 21 116 2.34E-19 T 12-10-2018 MIM_c23180 45da576eeb9cfd7535dccb966b908200 408 Pfam PF02754 Cysteine-rich domain 305 387 2.1E-11 T 12-10-2018 IPR004017 Cysteine-rich domain MIM_c23180 45da576eeb9cfd7535dccb966b908200 408 Pfam PF02754 Cysteine-rich domain 172 254 2.1E-7 T 12-10-2018 IPR004017 Cysteine-rich domain MIM_c23180 45da576eeb9cfd7535dccb966b908200 408 Pfam PF13183 4Fe-4S dicluster domain 22 89 1.4E-12 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MIM_c23180 45da576eeb9cfd7535dccb966b908200 408 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 25 36 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MIM_c23180 45da576eeb9cfd7535dccb966b908200 408 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MIM_c23180 45da576eeb9cfd7535dccb966b908200 408 PIRSF PIRSF000139 6 408 2.4E-101 T 12-10-2018 MIM_c22400 565c4f508d81b022bb8b73ab93fc3a28 388 Gene3D G3DSA:3.40.47.10 1 388 7.4E-92 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c22400 565c4f508d81b022bb8b73ab93fc3a28 388 Pfam PF00108 Thiolase, N-terminal domain 16 227 1.4E-14 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 MIM_c22400 565c4f508d81b022bb8b73ab93fc3a28 388 SUPERFAMILY SSF53901 13 362 6.57E-39 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c22400 565c4f508d81b022bb8b73ab93fc3a28 388 Pfam PF02803 Thiolase, C-terminal domain 252 360 1.1E-8 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 MIM_c22400 565c4f508d81b022bb8b73ab93fc3a28 388 PIRSF PIRSF000429 1 384 4.3E-55 T 12-10-2018 IPR002155 Thiolase GO:0016747 MIM_c08420 4bd6868a9d3fd4cb726034a82a429ebc 324 SUPERFAMILY SSF53850 117 283 2.82E-7 T 12-10-2018 MIM_c08420 4bd6868a9d3fd4cb726034a82a429ebc 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 320 4.0E-75 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c08420 4bd6868a9d3fd4cb726034a82a429ebc 324 Gene3D G3DSA:3.40.190.10 127 249 9.9E-100 T 12-10-2018 MIM_c08420 4bd6868a9d3fd4cb726034a82a429ebc 324 Gene3D G3DSA:3.40.190.150 29 314 9.9E-100 T 12-10-2018 MIM_c08420 4bd6868a9d3fd4cb726034a82a429ebc 324 PIRSF PIRSF017082 1 323 7.1E-70 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c27470 97a25469e8e25bb7796bfee07dd138e2 313 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 278 9.7E-43 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MIM_c27470 97a25469e8e25bb7796bfee07dd138e2 313 Gene3D G3DSA:3.40.50.720 97 279 2.9E-100 T 12-10-2018 MIM_c27470 97a25469e8e25bb7796bfee07dd138e2 313 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 217 233 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MIM_c27470 97a25469e8e25bb7796bfee07dd138e2 313 Gene3D G3DSA:3.40.50.720 17 313 2.9E-100 T 12-10-2018 MIM_c27470 97a25469e8e25bb7796bfee07dd138e2 313 SUPERFAMILY SSF51735 99 279 6.14E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c26430 608a0ee621e61c2f2e45c507393eb517 533 Gene3D G3DSA:3.90.76.10 51 209 8.6E-161 T 12-10-2018 MIM_c26430 608a0ee621e61c2f2e45c507393eb517 533 PIRSF PIRSF002741 7 532 6.3E-113 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MIM_c26430 608a0ee621e61c2f2e45c507393eb517 533 SUPERFAMILY SSF53850 28 532 3.98E-148 T 12-10-2018 MIM_c26430 608a0ee621e61c2f2e45c507393eb517 533 Gene3D G3DSA:3.40.190.10 210 521 8.6E-161 T 12-10-2018 MIM_c26430 608a0ee621e61c2f2e45c507393eb517 533 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 78 100 - T 12-10-2018 IPR023765 Solute-binding protein family 5, conserved site MIM_c26430 608a0ee621e61c2f2e45c507393eb517 533 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 72 451 1.7E-97 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain MIM_c26430 608a0ee621e61c2f2e45c507393eb517 533 Gene3D G3DSA:3.10.105.10 293 508 8.6E-161 T 12-10-2018 MIM_c24130 127f9ae7d1945b25b9f35bdbe594b5fa 116 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 92 110 - T 12-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 MIM_c24130 127f9ae7d1945b25b9f35bdbe594b5fa 116 Gene3D G3DSA:3.30.1330.40 1 116 2.8E-38 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MIM_c24130 127f9ae7d1945b25b9f35bdbe594b5fa 116 Pfam PF01042 Endoribonuclease L-PSP 14 115 4.1E-25 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 MIM_c24130 127f9ae7d1945b25b9f35bdbe594b5fa 116 SUPERFAMILY SSF55298 13 116 9.58E-29 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MIM_c34680 cea76ccb43f37470fe745d5a93e79904 260 TIGRFAM TIGR02312 HpaH: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase 1 259 1.7E-107 T 12-10-2018 IPR012690 2-oxo-hepta-4-ene-1,7-dioic acid hydratase GO:0018817|GO:0019439 MIM_c34680 cea76ccb43f37470fe745d5a93e79904 260 SUPERFAMILY SSF56529 2 259 6.8E-74 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MIM_c34680 cea76ccb43f37470fe745d5a93e79904 260 Gene3D G3DSA:3.90.850.10 1 260 2.5E-74 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MIM_c34680 cea76ccb43f37470fe745d5a93e79904 260 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 92 255 5.3E-6 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 MIM_c26920 556e095adaee972f8338b26f6951e540 370 Gene3D G3DSA:3.50.50.60 7 360 2.7E-140 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c26920 556e095adaee972f8338b26f6951e540 370 Pfam PF01266 FAD dependent oxidoreductase 8 365 2.4E-67 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MIM_c26920 556e095adaee972f8338b26f6951e540 370 Gene3D G3DSA:3.30.9.10 87 322 2.7E-140 T 12-10-2018 MIM_c26920 556e095adaee972f8338b26f6951e540 370 SUPERFAMILY SSF51905 7 368 2.46E-46 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c26920 556e095adaee972f8338b26f6951e540 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 4.9E-5 T 12-10-2018 MIM_c26920 556e095adaee972f8338b26f6951e540 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 197 212 4.9E-5 T 12-10-2018 MIM_c13700 0b7e613fc51949888a7cf9723edf19cf 357 SUPERFAMILY SSF53474 62 353 7.44E-30 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c13700 0b7e613fc51949888a7cf9723edf19cf 357 Gene3D G3DSA:3.40.50.1820 27 357 1.9E-106 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c29250 acf7fb226afa441f3f4e2dd5f4c0561c 373 Gene3D G3DSA:3.30.420.40 150 333 2.2E-120 T 12-10-2018 MIM_c29250 acf7fb226afa441f3f4e2dd5f4c0561c 373 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 11 373 2.9E-136 T 12-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 MIM_c29250 acf7fb226afa441f3f4e2dd5f4c0561c 373 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 10 373 39.778 T 12-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 MIM_c29250 acf7fb226afa441f3f4e2dd5f4c0561c 373 SUPERFAMILY SSF53067 11 344 1.15E-22 T 12-10-2018 MIM_c29250 acf7fb226afa441f3f4e2dd5f4c0561c 373 Gene3D G3DSA:3.30.420.40 17 368 2.2E-120 T 12-10-2018 MIM_c40770 a29b37be7cd75cd08d1d4fc861e433b0 232 Pfam PF02527 rRNA small subunit methyltransferase G 34 218 3.9E-43 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MIM_c40770 a29b37be7cd75cd08d1d4fc861e433b0 232 Gene3D G3DSA:3.40.50.150 6 232 1.2E-58 T 12-10-2018 MIM_c40770 a29b37be7cd75cd08d1d4fc861e433b0 232 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 27 223 24.572 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MIM_c40770 a29b37be7cd75cd08d1d4fc861e433b0 232 PIRSF PIRSF003078 14 229 2.5E-46 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MIM_c40770 a29b37be7cd75cd08d1d4fc861e433b0 232 SUPERFAMILY SSF53335 24 227 4.82E-33 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c40770 a29b37be7cd75cd08d1d4fc861e433b0 232 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 40 225 1.1E-39 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MIM_c30380 eb526bd8c011a0d57fa6111446c7cc39 203 Pfam PF01810 LysE type translocator 11 200 2.5E-34 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MIM_c30380 eb526bd8c011a0d57fa6111446c7cc39 203 PIRSF PIRSF006324 1 203 6.4E-45 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MIM_c17760 a295df8fbae526af4563bc4a7dc68119 188 Pfam PF00583 Acetyltransferase (GNAT) family 54 145 2.9E-11 T 12-10-2018 IPR000182 GNAT domain MIM_c17760 a295df8fbae526af4563bc4a7dc68119 188 TIGRFAM TIGR02406 ectoine_EctA: diaminobutyrate acetyltransferase 29 183 6.9E-62 T 12-10-2018 IPR012772 L-2,4-diaminobutyric acid acetyltransferase GO:0019491|GO:0033816 KEGG: 00260+2.3.1.178 MIM_c17760 a295df8fbae526af4563bc4a7dc68119 188 SUPERFAMILY SSF55729 27 146 5.32E-18 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c17760 a295df8fbae526af4563bc4a7dc68119 188 Gene3D G3DSA:3.40.630.30 26 187 5.0E-49 T 12-10-2018 MIM_c18900 d237550f01ae3fe9268675a08a597526 310 Pfam PF08340 Domain of unknown function (DUF1732) 217 310 2.0E-32 T 12-10-2018 IPR013551 Domain of unknown function DUF1732 MIM_c18900 d237550f01ae3fe9268675a08a597526 310 Pfam PF03755 YicC-like family, N-terminal region 2 154 1.9E-31 T 12-10-2018 IPR013527 YicC-like, N-terminal MIM_c18900 d237550f01ae3fe9268675a08a597526 310 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 310 1.9E-59 T 12-10-2018 IPR005229 Conserved hypothetical protein CHP00255 MIM_c18540 4a65726ba7e8265aecedde4f242b63a3 127 SUPERFAMILY SSF82649 1 125 5.76E-48 T 12-10-2018 MIM_c18540 4a65726ba7e8265aecedde4f242b63a3 127 Gene3D G3DSA:3.90.1010.10 1 127 1.6E-58 T 12-10-2018 MIM_c18540 4a65726ba7e8265aecedde4f242b63a3 127 Pfam PF01592 NifU-like N terminal domain 2 125 1.7E-56 T 12-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 MIM_c18540 4a65726ba7e8265aecedde4f242b63a3 127 TIGRFAM TIGR01999 iscU: FeS cluster assembly scaffold IscU 3 125 1.2E-68 T 12-10-2018 IPR011339 ISC system FeS cluster assembly, IscU scaffold GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 MIM_c34700 43dc275878684bd23eaff8157bd6c928 290 Gene3D G3DSA:3.20.20.140 9 290 4.6E-65 T 12-10-2018 MIM_c34700 43dc275878684bd23eaff8157bd6c928 290 Pfam PF04909 Amidohydrolase 24 288 4.5E-38 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MIM_c34700 43dc275878684bd23eaff8157bd6c928 290 SUPERFAMILY SSF51556 19 289 4.76E-66 T 12-10-2018 IPR032466 Metal-dependent hydrolase MIM_c29500 ef860663e62f519f371f697f536abe2b 246 Gene3D G3DSA:1.10.3810.10 57 244 2.2E-54 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c29500 ef860663e62f519f371f697f536abe2b 246 Pfam PF00912 Transglycosylase 71 239 9.4E-54 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c29500 ef860663e62f519f371f697f536abe2b 246 Hamap MF_00766 Biosynthetic peptidoglycan transglycosylase [mtgA]. 20 245 39.232 T 12-10-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c29500 ef860663e62f519f371f697f536abe2b 246 SUPERFAMILY SSF53955 68 241 9.56E-57 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily MIM_c29500 ef860663e62f519f371f697f536abe2b 246 TIGRFAM TIGR02070 mono_pep_trsgly: monofunctional biosynthetic peptidoglycan transglycosylase 21 243 6.1E-87 T 12-10-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c39450 0e0ff611c7057f4bfe4bd29e980b56c4 185 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 34 158 1.0E-22 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ MIM_c15920 684d1294b06305a0a16abda34bd035c6 385 Pfam PF13458 Periplasmic binding protein 24 364 8.8E-50 T 12-10-2018 IPR028081 Leucine-binding protein domain MIM_c15920 684d1294b06305a0a16abda34bd035c6 385 SUPERFAMILY SSF53822 23 381 3.44E-69 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c15920 684d1294b06305a0a16abda34bd035c6 385 Gene3D G3DSA:3.40.50.2300 140 378 1.2E-109 T 12-10-2018 MIM_c15920 684d1294b06305a0a16abda34bd035c6 385 Gene3D G3DSA:3.40.50.2300 26 367 1.2E-109 T 12-10-2018 MIM_c10270 aaceb06c63da3ba3ae83e04e089a9b3f 331 SUPERFAMILY SSF53474 31 309 1.19E-36 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c10270 aaceb06c63da3ba3ae83e04e089a9b3f 331 Pfam PF00561 alpha/beta hydrolase fold 69 302 2.8E-13 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c10270 aaceb06c63da3ba3ae83e04e089a9b3f 331 PIRSF PIRSF005211 2 331 2.1E-98 T 12-10-2018 IPR012020 AB hydrolase 4 family MIM_c10270 aaceb06c63da3ba3ae83e04e089a9b3f 331 Gene3D G3DSA:3.40.50.1820 38 309 1.3E-20 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c27990 19f9761b178e5f04bcfe58033589e063 352 Pfam PF02562 PhoH-like protein 140 343 1.8E-94 T 12-10-2018 IPR003714 PhoH-like protein GO:0005524 MIM_c27990 19f9761b178e5f04bcfe58033589e063 352 Gene3D G3DSA:3.40.50.300 137 343 1.1E-74 T 12-10-2018 MIM_c27990 19f9761b178e5f04bcfe58033589e063 352 SUPERFAMILY SSF52540 139 320 5.71E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c15780 06dab9a0daadb43759db3e0e54f51935 537 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 2 479 9.0E-132 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MIM_c15780 06dab9a0daadb43759db3e0e54f51935 537 PRINTS PR01806 Virulence factor MviN signature 159 180 6.4E-75 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MIM_c15780 06dab9a0daadb43759db3e0e54f51935 537 PRINTS PR01806 Virulence factor MviN signature 265 291 6.4E-75 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MIM_c15780 06dab9a0daadb43759db3e0e54f51935 537 PRINTS PR01806 Virulence factor MviN signature 415 432 6.4E-75 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MIM_c15780 06dab9a0daadb43759db3e0e54f51935 537 PRINTS PR01806 Virulence factor MviN signature 52 68 6.4E-75 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MIM_c15780 06dab9a0daadb43759db3e0e54f51935 537 PRINTS PR01806 Virulence factor MviN signature 135 159 6.4E-75 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MIM_c15780 06dab9a0daadb43759db3e0e54f51935 537 PRINTS PR01806 Virulence factor MviN signature 363 382 6.4E-75 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MIM_c15780 06dab9a0daadb43759db3e0e54f51935 537 PRINTS PR01806 Virulence factor MviN signature 33 52 6.4E-75 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MIM_c15780 06dab9a0daadb43759db3e0e54f51935 537 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 3 473 19.553 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MIM_c15780 06dab9a0daadb43759db3e0e54f51935 537 Pfam PF03023 MviN-like protein 28 474 7.4E-129 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MIM_c15780 06dab9a0daadb43759db3e0e54f51935 537 PIRSF PIRSF002869 1 537 9.2E-148 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MIM_c23850 112e202795aa8b3e1cdfafd5d7c75f0c 328 Pfam PF17188 MucB/RseB C-terminal domain 224 318 8.4E-21 T 12-10-2018 IPR033436 MucB/RseB, C-terminal MIM_c23850 112e202795aa8b3e1cdfafd5d7c75f0c 328 Pfam PF03888 MucB/RseB N-terminal domain 30 205 1.1E-54 T 12-10-2018 IPR033434 MucB/RseB, N-terminal MIM_c23850 112e202795aa8b3e1cdfafd5d7c75f0c 328 PIRSF PIRSF005427 3 324 9.1E-81 T 12-10-2018 IPR005588 MucB/RseB MIM_c23850 112e202795aa8b3e1cdfafd5d7c75f0c 328 Gene3D G3DSA:3.30.200.100 225 323 1.7E-14 T 12-10-2018 IPR038484 MucB/RseB, C-terminal domain superfamily MIM_c23850 112e202795aa8b3e1cdfafd5d7c75f0c 328 Gene3D G3DSA:2.50.20.10 29 205 6.3E-51 T 12-10-2018 MIM_c26710 7af33764d8202f919d60771393d37d38 365 Gene3D G3DSA:3.30.200.20 25 117 3.5E-22 T 12-10-2018 MIM_c26710 7af33764d8202f919d60771393d37d38 365 Pfam PF01636 Phosphotransferase enzyme family 49 276 1.9E-32 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase MIM_c26710 7af33764d8202f919d60771393d37d38 365 Gene3D G3DSA:3.90.1200.10 118 361 1.1E-68 T 12-10-2018 MIM_c26710 7af33764d8202f919d60771393d37d38 365 SUPERFAMILY SSF56112 32 344 1.02E-45 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily MIM_c08280 c6bf65cf2bd7fa278496efbe0e9d90b5 271 Gene3D G3DSA:3.40.50.720 7 235 5.3E-57 T 12-10-2018 MIM_c08280 c6bf65cf2bd7fa278496efbe0e9d90b5 271 SUPERFAMILY SSF51735 8 245 3.54E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c08280 c6bf65cf2bd7fa278496efbe0e9d90b5 271 Pfam PF01370 NAD dependent epimerase/dehydratase family 10 174 1.9E-18 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MIM_c12650 5511b429be8f11bd6b91dff4056bc739 279 Gene3D G3DSA:3.40.225.10 26 279 1.4E-63 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily MIM_c12650 5511b429be8f11bd6b91dff4056bc739 279 SMART SM01007 47 229 8.0E-46 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal MIM_c12650 5511b429be8f11bd6b91dff4056bc739 279 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 48 229 3.4E-37 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal MIM_c12650 5511b429be8f11bd6b91dff4056bc739 279 SUPERFAMILY SSF53639 42 247 3.34E-48 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily MIM_c25120 1c1b76b4ca9f72e072b815da85903b9e 371 Gene3D G3DSA:3.40.50.2000 34 363 3.8E-62 T 12-10-2018 MIM_c25120 1c1b76b4ca9f72e072b815da85903b9e 371 Pfam PF00534 Glycosyl transferases group 1 177 342 1.2E-33 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 MIM_c25120 1c1b76b4ca9f72e072b815da85903b9e 371 Gene3D G3DSA:3.40.50.2000 167 350 3.8E-62 T 12-10-2018 MIM_c25120 1c1b76b4ca9f72e072b815da85903b9e 371 Pfam PF13439 Glycosyltransferase Family 4 21 167 7.5E-12 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MIM_c25120 1c1b76b4ca9f72e072b815da85903b9e 371 SUPERFAMILY SSF53756 11 365 1.43E-66 T 12-10-2018 MIM_c13370 ebf670eb3a896e614f512f68855bc055 453 Pfam PF00579 tRNA synthetases class I (W and Y) 2 287 2.3E-53 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 MIM_c13370 ebf670eb3a896e614f512f68855bc055 453 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 202 212 1.8E-20 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MIM_c13370 ebf670eb3a896e614f512f68855bc055 453 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 13 29 1.8E-20 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MIM_c13370 ebf670eb3a896e614f512f68855bc055 453 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 65 84 1.8E-20 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MIM_c13370 ebf670eb3a896e614f512f68855bc055 453 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 148 169 1.8E-20 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MIM_c13370 ebf670eb3a896e614f512f68855bc055 453 SUPERFAMILY SSF52374 1 332 4.06E-80 T 12-10-2018 MIM_c13370 ebf670eb3a896e614f512f68855bc055 453 Gene3D G3DSA:3.40.50.620 2 332 3.8E-115 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c13370 ebf670eb3a896e614f512f68855bc055 453 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 2 332 6.0E-93 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MIM_c13370 ebf670eb3a896e614f512f68855bc055 453 SUPERFAMILY SSF160113 352 393 2.98E-5 T 12-10-2018 IPR036913 YegP-like superfamily MIM_c13370 ebf670eb3a896e614f512f68855bc055 453 Gene3D G3DSA:1.10.240.10 197 300 3.8E-115 T 12-10-2018 MIM_c13370 ebf670eb3a896e614f512f68855bc055 453 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 333 36.129 T 12-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 MIM_c32740 1cb304bdf910f59573863feb7aafadf2 391 PIRSF PIRSF000429 27 373 1.3E-8 T 12-10-2018 IPR002155 Thiolase GO:0016747 MIM_c32740 1cb304bdf910f59573863feb7aafadf2 391 SUPERFAMILY SSF53901 26 370 7.16E-17 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c32740 1cb304bdf910f59573863feb7aafadf2 391 Gene3D G3DSA:3.40.47.10 10 385 1.2E-78 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c04270 9273e9321dddef9b28dd19e410db5fd8 453 Gene3D G3DSA:1.10.4100.10 29 415 1.4E-112 T 12-10-2018 MIM_c04270 9273e9321dddef9b28dd19e410db5fd8 453 Pfam PF03972 MmgE/PrpD family 8 417 4.0E-96 T 12-10-2018 IPR005656 MmgE/PrpD GO:0016829 MIM_c04270 9273e9321dddef9b28dd19e410db5fd8 453 SUPERFAMILY SSF103378 14 440 4.97E-93 T 12-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 MIM_c04270 9273e9321dddef9b28dd19e410db5fd8 453 Gene3D G3DSA:3.30.1330.120 270 397 1.4E-112 T 12-10-2018 MIM_c34200 9b91cc4253376b23675cb9731c54f6fd 191 Pfam PF11706 CGNR zinc finger 141 181 8.7E-15 T 12-10-2018 IPR021005 Zinc finger, CGNR MIM_c34200 9b91cc4253376b23675cb9731c54f6fd 191 Pfam PF07336 Putative stress-induced transcription regulator 14 135 3.7E-19 T 12-10-2018 IPR010852 Putative stress-induced transcription regulator MIM_c34200 9b91cc4253376b23675cb9731c54f6fd 191 SUPERFAMILY SSF160904 6 179 1.83E-39 T 12-10-2018 MIM_c34200 9b91cc4253376b23675cb9731c54f6fd 191 Gene3D G3DSA:1.10.3300.10 8 185 1.3E-27 T 12-10-2018 IPR023286 ABATE domain superfamily MIM_c21760 fc4494316d0c05c001046da06a654cdb 173 Pfam PF13628 Domain of unknown function (DUF4142) 27 168 1.0E-39 T 12-10-2018 IPR025419 Domain of unknown function DUF4142 MIM_c34940 945c77897d10e7970ca45d8126683a5e 394 Pfam PF00296 Luciferase-like monooxygenase 31 356 1.3E-76 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MIM_c34940 945c77897d10e7970ca45d8126683a5e 394 SUPERFAMILY SSF51679 27 387 1.83E-87 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MIM_c34940 945c77897d10e7970ca45d8126683a5e 394 Gene3D G3DSA:3.20.20.30 26 385 9.1E-85 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MIM_c19950 6c24e3109caa6d57aa1e8e5431ca767e 226 Pfam PF03737 Aldolase/RraA 23 177 6.3E-34 T 12-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MIM_c19950 6c24e3109caa6d57aa1e8e5431ca767e 226 Gene3D G3DSA:3.50.30.100 1 200 2.1E-56 T 12-10-2018 MIM_c19950 6c24e3109caa6d57aa1e8e5431ca767e 226 SUPERFAMILY SSF89562 21 188 1.31E-38 T 12-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily MIM_c37590 4c5bb2987fe6ef39320b03ed636dd85e 391 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 9 386 3.2E-127 T 12-10-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 MIM_c33050 7987df0a2c3efc0975ceb773d0083b78 335 Gene3D G3DSA:3.40.190.10 105 308 1.6E-62 T 12-10-2018 MIM_c33050 7987df0a2c3efc0975ceb773d0083b78 335 Gene3D G3DSA:3.40.190.10 186 284 1.6E-62 T 12-10-2018 MIM_c33050 7987df0a2c3efc0975ceb773d0083b78 335 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 60 71 2.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c33050 7987df0a2c3efc0975ceb773d0083b78 335 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c33050 7987df0a2c3efc0975ceb773d0083b78 335 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 60 2.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c33050 7987df0a2c3efc0975ceb773d0083b78 335 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 24 82 7.8E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c33050 7987df0a2c3efc0975ceb773d0083b78 335 Gene3D G3DSA:1.10.10.10 14 102 2.2E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c33050 7987df0a2c3efc0975ceb773d0083b78 335 Pfam PF03466 LysR substrate binding domain 111 310 3.4E-30 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c33050 7987df0a2c3efc0975ceb773d0083b78 335 SUPERFAMILY SSF46785 20 100 1.63E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c33050 7987df0a2c3efc0975ceb773d0083b78 335 SUPERFAMILY SSF53850 105 312 2.04E-43 T 12-10-2018 MIM_c06900 8b21c57593bf0e3d712bdb81a0bda814 442 Pfam PF13489 Methyltransferase domain 38 142 7.9E-15 T 12-10-2018 MIM_c06900 8b21c57593bf0e3d712bdb81a0bda814 442 Gene3D G3DSA:3.40.50.150 1 222 7.9E-53 T 12-10-2018 MIM_c06900 8b21c57593bf0e3d712bdb81a0bda814 442 SUPERFAMILY SSF53335 25 193 5.73E-31 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c15070 8ea5e5d132e51d80418970972a98dd94 240 Hamap MF_00521 3-deoxy-D-manno-octulosonic acid kinase [kdkA]. 10 239 27.907 T 12-10-2018 IPR022826 3-deoxy-D-manno-octulosonic acid kinase GO:0016773 KEGG: 00540+2.7.1.166|MetaCyc: PWY-7675|MetaCyc: PWY-7676 MIM_c15070 8ea5e5d132e51d80418970972a98dd94 240 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 39 219 8.5E-49 T 12-10-2018 MIM_c15070 8ea5e5d132e51d80418970972a98dd94 240 Gene3D G3DSA:1.10.510.10 142 240 3.2E-13 T 12-10-2018 MIM_c15070 8ea5e5d132e51d80418970972a98dd94 240 SUPERFAMILY SSF56112 44 198 4.32E-15 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily MIM_c20000 34e143945a1ae7a0fdd2133db278c26b 344 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 46 294 2.8E-29 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 MIM_c20000 34e143945a1ae7a0fdd2133db278c26b 344 Gene3D G3DSA:3.40.190.170 34 340 1.9E-67 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily MIM_c20000 34e143945a1ae7a0fdd2133db278c26b 344 SUPERFAMILY SSF53850 130 256 3.43E-6 T 12-10-2018 MIM_c01820 ea8a3523e776f65f72c2e5de26739e69 363 Pfam PF01032 FecCD transport family 43 357 1.1E-83 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MIM_c01820 ea8a3523e776f65f72c2e5de26739e69 363 Gene3D G3DSA:1.10.3470.10 29 362 5.6E-96 T 12-10-2018 IPR037294 ABC transporter, BtuC-like MIM_c01820 ea8a3523e776f65f72c2e5de26739e69 363 SUPERFAMILY SSF81345 25 358 2.35E-79 T 12-10-2018 IPR037294 ABC transporter, BtuC-like MIM_c02490 508710bf863cc5fe5fd7c1e74a7007a7 395 SUPERFAMILY SSF89796 3 392 3.4E-122 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c02490 508710bf863cc5fe5fd7c1e74a7007a7 395 Gene3D G3DSA:3.30.1540.10 223 321 8.1E-114 T 12-10-2018 MIM_c02490 508710bf863cc5fe5fd7c1e74a7007a7 395 Pfam PF02515 CoA-transferase family III 9 369 1.4E-113 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 MIM_c02490 508710bf863cc5fe5fd7c1e74a7007a7 395 Gene3D G3DSA:3.40.50.10540 7 386 8.1E-114 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c02180 bd92355a6fbfe7c8db10ab4b8c0ba71e 458 Gene3D G3DSA:3.10.180.80 4 446 1.2E-190 T 12-10-2018 MIM_c02180 bd92355a6fbfe7c8db10ab4b8c0ba71e 458 Pfam PF07063 Domain of unknown function (DUF1338) 11 409 3.4E-118 T 12-10-2018 IPR009770 Domain of unknown function DUF1338 MIM_c02180 bd92355a6fbfe7c8db10ab4b8c0ba71e 458 SMART SM01150 13 409 7.2E-214 T 12-10-2018 IPR009770 Domain of unknown function DUF1338 MIM_c18240 ea450c3b527350b1723ad3016018118d 377 Pfam PF02353 Mycolic acid cyclopropane synthetase 101 361 2.1E-93 T 12-10-2018 MIM_c18240 ea450c3b527350b1723ad3016018118d 377 SUPERFAMILY SSF53335 110 363 1.64E-75 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c18240 ea450c3b527350b1723ad3016018118d 377 Gene3D G3DSA:3.40.50.150 110 368 7.5E-97 T 12-10-2018 MIM_c18240 ea450c3b527350b1723ad3016018118d 377 PIRSF PIRSF003085 4 375 1.8E-118 T 12-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 MIM_c39440 4f127b4725aad4c1b78f9df13162099b 426 PIRSF PIRSF006066 1 426 1.9E-137 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 MIM_c39440 4f127b4725aad4c1b78f9df13162099b 426 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 8 417 4.7E-112 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit MIM_c39440 4f127b4725aad4c1b78f9df13162099b 426 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 420 1.1E-136 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 MIM_c32550 66ed1cfb9b0018f2dab853475c110749 381 Gene3D G3DSA:3.40.50.2000 195 362 1.2E-43 T 12-10-2018 MIM_c32550 66ed1cfb9b0018f2dab853475c110749 381 SUPERFAMILY SSF53756 14 373 7.01E-78 T 12-10-2018 MIM_c32550 66ed1cfb9b0018f2dab853475c110749 381 Gene3D G3DSA:3.40.50.2000 12 194 2.1E-21 T 12-10-2018 MIM_c32550 66ed1cfb9b0018f2dab853475c110749 381 Pfam PF13439 Glycosyltransferase Family 4 24 179 1.2E-20 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MIM_c32550 66ed1cfb9b0018f2dab853475c110749 381 Pfam PF00534 Glycosyl transferases group 1 196 351 3.1E-36 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 MIM_c03990 699400f1d9e180e458a171671ec5ca48 410 Pfam PF13379 NMT1-like family 86 276 1.5E-11 T 12-10-2018 MIM_c03990 699400f1d9e180e458a171671ec5ca48 410 Gene3D G3DSA:3.40.190.10 81 338 9.5E-52 T 12-10-2018 MIM_c03990 699400f1d9e180e458a171671ec5ca48 410 Gene3D G3DSA:3.40.190.10 140 237 9.5E-52 T 12-10-2018 MIM_c03990 699400f1d9e180e458a171671ec5ca48 410 SUPERFAMILY SSF53850 78 283 4.15E-29 T 12-10-2018 MIM_c04430 77eb51229da6d9b6715161044be50355 331 Gene3D G3DSA:3.55.50.30 254 327 1.3E-5 T 12-10-2018 MIM_c04430 77eb51229da6d9b6715161044be50355 331 PIRSF PIRSF018266 6 330 9.1E-76 T 12-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component MIM_c04430 77eb51229da6d9b6715161044be50355 331 Pfam PF04773 FecR protein 121 212 2.6E-21 T 12-10-2018 IPR006860 FecR protein MIM_c04430 77eb51229da6d9b6715161044be50355 331 Pfam PF16220 Domain of unknown function (DUF4880) 15 56 2.6E-9 T 12-10-2018 IPR032623 FecR, N-terminal MIM_c04430 77eb51229da6d9b6715161044be50355 331 Pfam PF16344 Domain of unknown function (DUF4974) 242 319 1.4E-8 T 12-10-2018 IPR032508 Protein FecR, C-terminal MIM_c04430 77eb51229da6d9b6715161044be50355 331 Gene3D G3DSA:2.60.120.1440 108 246 3.3E-25 T 12-10-2018 MIM_c29610 856f981975c1883fb4ca9054985f7eb6 425 Pfam PF00202 Aminotransferase class-III 32 394 2.8E-74 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MIM_c29610 856f981975c1883fb4ca9054985f7eb6 425 Gene3D G3DSA:3.40.640.10 69 317 6.9E-173 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c29610 856f981975c1883fb4ca9054985f7eb6 425 Gene3D G3DSA:3.90.1150.10 7 417 6.9E-173 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c29610 856f981975c1883fb4ca9054985f7eb6 425 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 234 270 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MIM_c29610 856f981975c1883fb4ca9054985f7eb6 425 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 3 425 102.35 T 12-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 MIM_c29610 856f981975c1883fb4ca9054985f7eb6 425 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 4 423 2.7E-184 T 12-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 MIM_c29610 856f981975c1883fb4ca9054985f7eb6 425 SUPERFAMILY SSF53383 2 422 2.11E-129 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c24520 fa21503e25334d1bb32eda2ad67ed787 364 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 240 253 - T 12-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24520 fa21503e25334d1bb32eda2ad67ed787 364 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 28 359 24.82 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c24520 fa21503e25334d1bb32eda2ad67ed787 364 Pfam PF00146 NADH dehydrogenase 35 352 3.1E-125 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c20490 7b67df0a579931804abade03adcc5081 545 Pfam PF00732 GMC oxidoreductase 14 305 8.4E-81 T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c20490 7b67df0a579931804abade03adcc5081 545 PIRSF PIRSF000137 1 545 5.2E-144 T 12-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c20490 7b67df0a579931804abade03adcc5081 545 Gene3D G3DSA:3.50.50.60 14 540 9.5E-171 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c20490 7b67df0a579931804abade03adcc5081 545 Pfam PF05199 GMC oxidoreductase 401 536 8.2E-39 T 12-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 MIM_c20490 7b67df0a579931804abade03adcc5081 545 SUPERFAMILY SSF51905 11 545 1.3E-84 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c20490 7b67df0a579931804abade03adcc5081 545 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 92 115 - T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c20490 7b67df0a579931804abade03adcc5081 545 SUPERFAMILY SSF54373 300 486 2.35E-38 T 12-10-2018 MIM_c20490 7b67df0a579931804abade03adcc5081 545 Gene3D G3DSA:3.30.410.40 161 483 9.5E-171 T 12-10-2018 MIM_c20490 7b67df0a579931804abade03adcc5081 545 Gene3D G3DSA:1.10.1220.110 107 160 9.5E-171 T 12-10-2018 MIM_c20490 7b67df0a579931804abade03adcc5081 545 Gene3D G3DSA:4.10.450.10 47 206 9.5E-171 T 12-10-2018 IPR027424 Glucose Oxidase, domain 2 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 MIM_c20490 7b67df0a579931804abade03adcc5081 545 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 264 278 - T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MIM_c40650 c0c6d6fd596551ffcd6b7428aa22b6bd 174 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 160 27.409 T 12-10-2018 IPR022973 Ribosomal protein L10 MIM_c40650 c0c6d6fd596551ffcd6b7428aa22b6bd 174 Pfam PF00466 Ribosomal protein L10 4 100 5.8E-24 T 12-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 MIM_c40650 c0c6d6fd596551ffcd6b7428aa22b6bd 174 SUPERFAMILY SSF160369 4 171 1.01E-56 T 12-10-2018 MIM_c40650 c0c6d6fd596551ffcd6b7428aa22b6bd 174 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 21 159 0.002 T 12-10-2018 MIM_c40650 c0c6d6fd596551ffcd6b7428aa22b6bd 174 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 12-10-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c40650 c0c6d6fd596551ffcd6b7428aa22b6bd 174 Gene3D G3DSA:3.30.70.1730 3 133 3.9E-35 T 12-10-2018 MIM_c04920 a174e69711deb9aca8b55128737f5555 86 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 49 3.4E-23 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 MIM_c04920 a174e69711deb9aca8b55128737f5555 86 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 86 22.129 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 MIM_c04920 a174e69711deb9aca8b55128737f5555 86 Pfam PF02416 mttA/Hcf106 family 4 55 1.7E-15 T 12-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 MIM_c17060 c894a2466d272168d320f945039ee0ff 327 Gene3D G3DSA:3.40.190.10 128 251 2.9E-113 T 12-10-2018 MIM_c17060 c894a2466d272168d320f945039ee0ff 327 PIRSF PIRSF017082 1 325 3.6E-92 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c17060 c894a2466d272168d320f945039ee0ff 327 SUPERFAMILY SSF53850 114 287 3.13E-18 T 12-10-2018 MIM_c17060 c894a2466d272168d320f945039ee0ff 327 Gene3D G3DSA:3.40.190.150 31 316 2.9E-113 T 12-10-2018 MIM_c17060 c894a2466d272168d320f945039ee0ff 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 322 5.3E-86 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c23540 e9679bbd14ce0c602cb003a2f912e112 410 Pfam PF13449 Esterase-like activity of phytase 37 374 6.8E-62 T 12-10-2018 IPR027372 Phytase-like domain MIM_c23540 e9679bbd14ce0c602cb003a2f912e112 410 SUPERFAMILY SSF101898 140 315 4.97E-8 T 12-10-2018 MIM_c10640 4c0114bd54c4b7fb9d9f91e526db3870 93 SUPERFAMILY SSF47413 1 38 9.85E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c10640 4c0114bd54c4b7fb9d9f91e526db3870 93 Gene3D G3DSA:1.10.260.40 1 93 6.1E-8 T 12-10-2018 MIM_c10640 4c0114bd54c4b7fb9d9f91e526db3870 93 Pfam PF01381 Helix-turn-helix 1 33 1.1E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c23960 1dcd38775e6f90386cc63da04498f67d 184 Pfam PF02620 Uncharacterized ACR, COG1399 71 182 2.0E-11 T 12-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD MIM_c23190 18f39f437b1be8d0c583ac5a05059492 365 SUPERFAMILY SSF55103 137 362 3.07E-7 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MIM_c23190 18f39f437b1be8d0c583ac5a05059492 365 Gene3D G3DSA:3.30.465.40 5 191 1.3E-28 T 12-10-2018 MIM_c23190 18f39f437b1be8d0c583ac5a05059492 365 SUPERFAMILY SSF56176 6 175 8.72E-31 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MIM_c23190 18f39f437b1be8d0c583ac5a05059492 365 Pfam PF01565 FAD binding domain 6 137 2.2E-17 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MIM_c11540 a6c6636fb3fa04f636619b2c3fa90b02 291 Pfam PF03476 MOSC N-terminal beta barrel domain 4 122 3.2E-29 T 12-10-2018 IPR005303 MOSC, N-terminal beta barrel KEGG: 00790+2.8.1.9|MetaCyc: PWY-5963 MIM_c11540 a6c6636fb3fa04f636619b2c3fa90b02 291 Pfam PF03473 MOSC domain 158 286 8.2E-22 T 12-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 MIM_c11540 a6c6636fb3fa04f636619b2c3fa90b02 291 SUPERFAMILY SSF141673 5 138 1.57E-33 T 12-10-2018 MIM_c11540 a6c6636fb3fa04f636619b2c3fa90b02 291 SUPERFAMILY SSF50800 128 285 3.24E-9 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily MIM_c02610 c6598d8c2be354f38b3402fe95bec7ae 321 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c02610 c6598d8c2be354f38b3402fe95bec7ae 321 Pfam PF00005 ABC transporter 31 173 8.7E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c02610 c6598d8c2be354f38b3402fe95bec7ae 321 SMART SM00382 40 221 1.5E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c02610 c6598d8c2be354f38b3402fe95bec7ae 321 SUPERFAMILY SSF52540 12 236 1.24E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c02610 c6598d8c2be354f38b3402fe95bec7ae 321 Gene3D G3DSA:3.40.50.300 2 248 1.6E-65 T 12-10-2018 MIM_c22180 26ca3f8a36a68583b71080f77b1c88d7 551 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 74 237 2.3E-22 T 12-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like MIM_c19880 f6ce17d051b7ccf6c96b1e10fabe613d 262 Pfam PF04116 Fatty acid hydroxylase superfamily 105 234 3.7E-23 T 12-10-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 MIM_c24390 076e2da1c9d493e952374debc279eda2 240 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 4 239 35.049 T 12-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MIM_c24390 076e2da1c9d493e952374debc279eda2 240 Gene3D G3DSA:3.90.550.10 1 240 1.1E-58 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MIM_c24390 076e2da1c9d493e952374debc279eda2 240 SUPERFAMILY SSF53448 5 239 4.06E-45 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MIM_c24390 076e2da1c9d493e952374debc279eda2 240 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 6 238 3.2E-51 T 12-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MIM_c35600 4f5239e7cb34cdd9e2d18b06f9b9eb69 297 Gene3D G3DSA:3.40.50.720 2 161 7.3E-43 T 12-10-2018 MIM_c35600 4f5239e7cb34cdd9e2d18b06f9b9eb69 297 SUPERFAMILY SSF51735 4 157 1.79E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c35600 4f5239e7cb34cdd9e2d18b06f9b9eb69 297 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 156 3.2E-39 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 MIM_c35600 4f5239e7cb34cdd9e2d18b06f9b9eb69 297 SUPERFAMILY SSF48179 162 291 3.97E-29 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c35600 4f5239e7cb34cdd9e2d18b06f9b9eb69 297 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 163 284 2.5E-33 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MIM_c35600 4f5239e7cb34cdd9e2d18b06f9b9eb69 297 Gene3D G3DSA:1.10.1040.10 163 293 5.4E-32 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MIM_c35600 4f5239e7cb34cdd9e2d18b06f9b9eb69 297 PIRSF PIRSF000103 1 292 1.2E-61 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 MIM_c21870 0ae349d139499f54c010f22da2a123e3 213 Gene3D G3DSA:1.20.120.20 28 168 3.5E-6 T 12-10-2018 MIM_c20060 21c1219964ed1b38026ad071ef844a0c 303 Hamap MF_00694 Probable 5-dehydro-4-deoxyglucarate dehydratase. 10 300 42.352 T 12-10-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 MIM_c20060 21c1219964ed1b38026ad071ef844a0c 303 Pfam PF00701 Dihydrodipicolinate synthetase family 12 297 5.4E-45 T 12-10-2018 IPR002220 DapA-like GO:0016829 MIM_c20060 21c1219964ed1b38026ad071ef844a0c 303 SMART SM01130 10 300 1.1E-69 T 12-10-2018 IPR002220 DapA-like GO:0016829 MIM_c20060 21c1219964ed1b38026ad071ef844a0c 303 PIRSF PIRSF001365 6 303 1.3E-58 T 12-10-2018 IPR002220 DapA-like GO:0016829 MIM_c20060 21c1219964ed1b38026ad071ef844a0c 303 TIGRFAM TIGR03249 KdgD: 5-dehydro-4-deoxyglucarate dehydratase 3 298 4.8E-121 T 12-10-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 MIM_c20060 21c1219964ed1b38026ad071ef844a0c 303 Gene3D G3DSA:3.20.20.70 1 302 1.3E-101 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c20060 21c1219964ed1b38026ad071ef844a0c 303 SUPERFAMILY SSF51569 11 298 1.88E-64 T 12-10-2018 MIM_c36440 9dcb3a52de7baef74dc66a7034f41f99 176 SUPERFAMILY SSF50475 16 161 1.01E-24 T 12-10-2018 MIM_c36440 9dcb3a52de7baef74dc66a7034f41f99 176 Gene3D G3DSA:2.30.110.10 9 174 5.8E-45 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MIM_c36440 9dcb3a52de7baef74dc66a7034f41f99 176 PIRSF PIRSF004633 1 172 3.5E-46 T 12-10-2018 IPR014419 Heme utilization protein with pyridoxamine 5'-phosphate domain MIM_c36440 9dcb3a52de7baef74dc66a7034f41f99 176 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 15 89 2.1E-6 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MIM_c07530 be6d4f481c9793e218de67bc4893cee7 142 Gene3D G3DSA:2.60.15.10 1 134 3.9E-37 T 12-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07530 be6d4f481c9793e218de67bc4893cee7 142 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 10 85 4.0E-28 T 12-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07530 be6d4f481c9793e218de67bc4893cee7 142 SUPERFAMILY SSF46604 89 135 2.09E-6 T 12-10-2018 IPR036794 ATP synthase delta/epsilon subunit, C-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07530 be6d4f481c9793e218de67bc4893cee7 142 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 5 131 1.2E-39 T 12-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07530 be6d4f481c9793e218de67bc4893cee7 142 SUPERFAMILY SSF51344 4 86 5.62E-23 T 12-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07530 be6d4f481c9793e218de67bc4893cee7 142 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 84 3.9E-28 T 12-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c07530 be6d4f481c9793e218de67bc4893cee7 142 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 131 20.814 T 12-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MIM_c15860 1e0948297e8c212e1d67fe8542cd6fad 82 PRINTS PR00050 Cold shock protein signature 19 34 4.3E-17 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MIM_c15860 1e0948297e8c212e1d67fe8542cd6fad 82 PRINTS PR00050 Cold shock protein signature 40 49 4.3E-17 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MIM_c15860 1e0948297e8c212e1d67fe8542cd6fad 82 PRINTS PR00050 Cold shock protein signature 55 73 4.3E-17 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MIM_c15860 1e0948297e8c212e1d67fe8542cd6fad 82 SUPERFAMILY SSF50249 16 80 6.21E-26 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c15860 1e0948297e8c212e1d67fe8542cd6fad 82 Gene3D G3DSA:2.40.50.140 2 79 1.8E-30 T 12-10-2018 MIM_c15860 1e0948297e8c212e1d67fe8542cd6fad 82 ProSitePatterns PS00352 'Cold-shock' domain signature. 30 49 - T 12-10-2018 IPR019844 Cold-shock conserved site MIM_c15860 1e0948297e8c212e1d67fe8542cd6fad 82 PIRSF PIRSF002599 13 82 1.3E-24 T 12-10-2018 IPR012156 Cold shock, CspA GO:0003676 MIM_c15860 1e0948297e8c212e1d67fe8542cd6fad 82 SMART SM00357 18 82 2.2E-32 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 MIM_c15860 1e0948297e8c212e1d67fe8542cd6fad 82 Pfam PF00313 'Cold-shock' DNA-binding domain 18 80 2.5E-30 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MIM_c35560 267686e5ec7a6b781765c487a4d7dcab 295 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 167 285 1.9E-30 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MIM_c35560 267686e5ec7a6b781765c487a4d7dcab 295 PIRSF PIRSF000103 1 281 1.1E-62 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 MIM_c35560 267686e5ec7a6b781765c487a4d7dcab 295 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 161 1.9E-47 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 MIM_c35560 267686e5ec7a6b781765c487a4d7dcab 295 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 8 21 - T 12-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 MIM_c35560 267686e5ec7a6b781765c487a4d7dcab 295 SUPERFAMILY SSF51735 5 166 1.9E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c35560 267686e5ec7a6b781765c487a4d7dcab 295 SUPERFAMILY SSF48179 166 292 7.14E-22 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c35560 267686e5ec7a6b781765c487a4d7dcab 295 Gene3D G3DSA:3.40.50.720 1 166 4.4E-53 T 12-10-2018 MIM_c35560 267686e5ec7a6b781765c487a4d7dcab 295 Gene3D G3DSA:1.10.1040.10 167 294 1.1E-25 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MIM_c30780 14a9b8ca39143598fc911678c69abaf9 199 SUPERFAMILY SSF52518 10 176 9.47E-32 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c30780 14a9b8ca39143598fc911678c69abaf9 199 Gene3D G3DSA:3.40.50.970 4 186 1.7E-29 T 12-10-2018 MIM_c30780 14a9b8ca39143598fc911678c69abaf9 199 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 51 164 1.0E-18 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MIM_c32860 c2d13a23f6f698f81e68c70438d4764f 286 Gene3D G3DSA:1.10.3720.10 12 278 6.7E-58 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c32860 c2d13a23f6f698f81e68c70438d4764f 286 SUPERFAMILY SSF161098 21 286 2.99E-60 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c32860 c2d13a23f6f698f81e68c70438d4764f 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 281 6.6E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c31670 9e9432820ee5729517a6954fb7eb5c44 312 SUPERFAMILY SSF51395 1 298 5.33E-75 T 12-10-2018 MIM_c31670 9e9432820ee5729517a6954fb7eb5c44 312 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 298 33.186 T 12-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 MIM_c31670 9e9432820ee5729517a6954fb7eb5c44 312 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 236 256 - T 12-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 MIM_c31670 9e9432820ee5729517a6954fb7eb5c44 312 Pfam PF01180 Dihydroorotate dehydrogenase 5 280 1.3E-61 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 MIM_c31670 9e9432820ee5729517a6954fb7eb5c44 312 PIRSF PIRSF000164 1 300 1.5E-65 T 12-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 MIM_c31670 9e9432820ee5729517a6954fb7eb5c44 312 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 38 57 - T 12-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 MIM_c31670 9e9432820ee5729517a6954fb7eb5c44 312 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 6 297 8.9E-92 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 MIM_c31670 9e9432820ee5729517a6954fb7eb5c44 312 Gene3D G3DSA:3.20.20.70 3 302 1.0E-81 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c03080 09a8ccfed4f22947cb200579db30774d 213 SUPERFAMILY SSF52540 1 159 1.97E-9 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c03080 09a8ccfed4f22947cb200579db30774d 213 Gene3D G3DSA:3.40.50.300 1 196 1.8E-13 T 12-10-2018 MIM_c40490 5d6cf36cfd77904c8a84b6e72dbd49aa 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.9E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c40490 5d6cf36cfd77904c8a84b6e72dbd49aa 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.9E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c40490 5d6cf36cfd77904c8a84b6e72dbd49aa 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 7.3E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c40490 5d6cf36cfd77904c8a84b6e72dbd49aa 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 7.3E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c40490 5d6cf36cfd77904c8a84b6e72dbd49aa 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 7.3E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c40490 5d6cf36cfd77904c8a84b6e72dbd49aa 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 7.3E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c40490 5d6cf36cfd77904c8a84b6e72dbd49aa 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 7.3E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c40490 5d6cf36cfd77904c8a84b6e72dbd49aa 243 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 190 3.9E-4 T 12-10-2018 MIM_c40490 5d6cf36cfd77904c8a84b6e72dbd49aa 243 TIGRFAM TIGR01831 fabG_rel: putative 3-oxoacyl-(acyl-carrier-protein) reductase 7 242 4.4E-115 T 12-10-2018 IPR011285 3-oxoacyl-(acyl-carrier-protein) reductase, putative KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MIM_c40490 5d6cf36cfd77904c8a84b6e72dbd49aa 243 Gene3D G3DSA:3.40.50.720 1 243 2.8E-75 T 12-10-2018 MIM_c40490 5d6cf36cfd77904c8a84b6e72dbd49aa 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 242 5.1E-55 T 12-10-2018 MIM_c40490 5d6cf36cfd77904c8a84b6e72dbd49aa 243 SUPERFAMILY SSF51735 5 242 3.04E-71 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c18860 d785244a648a109b5252be152a47f0e3 68 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 57 3.5E-19 T 12-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c18860 d785244a648a109b5252be152a47f0e3 68 SUPERFAMILY SSF63562 1 64 8.2E-21 T 12-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 MIM_c18860 d785244a648a109b5252be152a47f0e3 68 SMART SM01409 8 60 1.5E-12 T 12-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 MIM_c18860 d785244a648a109b5252be152a47f0e3 68 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 61 15.633 T 12-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MIM_c18860 d785244a648a109b5252be152a47f0e3 68 Gene3D G3DSA:3.90.940.10 1 68 2.3E-22 T 12-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 MIM_c18860 d785244a648a109b5252be152a47f0e3 68 Pfam PF01192 RNA polymerase Rpb6 8 57 5.2E-14 T 12-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 MIM_c19500 1b32fec8cea2a31cb92ed49ba2d53d3c 281 Pfam PF03618 Kinase/pyrophosphorylase 10 268 1.3E-75 T 12-10-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 MIM_c19500 1b32fec8cea2a31cb92ed49ba2d53d3c 281 Hamap MF_01062 Phosphoenolpyruvate synthase regulatory protein [ppsR]. 7 277 69.19 T 12-10-2018 IPR026530 Phosphoenolpyruvate synthase regulatory protein MIM_c18780 94909835749f35e48276f00ced4d45e4 307 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 2.3E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c18780 94909835749f35e48276f00ced4d45e4 307 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 2.3E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c18780 94909835749f35e48276f00ced4d45e4 307 Pfam PF00561 alpha/beta hydrolase fold 33 292 5.4E-16 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c18780 94909835749f35e48276f00ced4d45e4 307 Gene3D G3DSA:3.40.50.1820 9 306 6.1E-70 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c18780 94909835749f35e48276f00ced4d45e4 307 SUPERFAMILY SSF53474 18 296 4.74E-38 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c09060 32b0968bb17a7fe288a39d3fc9f87360 178 Pfam PF04093 rod shape-determining protein MreD 27 162 1.8E-7 T 12-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 MIM_c09060 32b0968bb17a7fe288a39d3fc9f87360 178 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 24 160 4.2E-16 T 12-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 MIM_24p00140 42243cdc8a1626a1e7e3b0ae60e39577 288 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 79 282 4.4E-50 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 MIM_24p00140 42243cdc8a1626a1e7e3b0ae60e39577 288 Gene3D G3DSA:3.90.850.10 48 285 8.0E-61 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MIM_24p00140 42243cdc8a1626a1e7e3b0ae60e39577 288 SUPERFAMILY SSF56529 69 282 2.75E-55 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MIM_c22060 9d91b76626e1d3d2850f31d40ce3c919 548 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 248 543 1.1E-121 T 12-10-2018 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type MIM_c22060 9d91b76626e1d3d2850f31d40ce3c919 548 Pfam PF02653 Branched-chain amino acid transport system / permease component 250 529 4.8E-55 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c37270 9403e9f38e125fe155787cba4802f05a 592 Pfam PF02026 RyR domain 510 563 2.8E-10 T 12-10-2018 IPR003032 Ryanodine receptor Ryr Reactome: R-HSA-2672351|Reactome: R-HSA-5578775 MIM_c37270 9403e9f38e125fe155787cba4802f05a 592 Pfam PF02254 TrkA-N domain 109 199 2.5E-12 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MIM_c37270 9403e9f38e125fe155787cba4802f05a 592 SUPERFAMILY SSF51735 106 201 8.56E-11 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c37270 9403e9f38e125fe155787cba4802f05a 592 Gene3D G3DSA:3.40.50.720 108 255 3.8E-15 T 12-10-2018 MIM_c37270 9403e9f38e125fe155787cba4802f05a 592 Gene3D G3DSA:1.10.490.160 503 567 5.6E-9 T 12-10-2018 MIM_c34340 ac1ccfe3b6daae4527082b2ba4bc5489 299 SUPERFAMILY SSF161098 28 296 3.92E-44 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c34340 ac1ccfe3b6daae4527082b2ba4bc5489 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 283 5.5E-9 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c34340 ac1ccfe3b6daae4527082b2ba4bc5489 299 Gene3D G3DSA:1.10.3720.10 25 293 5.0E-37 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c22860 3459eba3998ddf3e75d57b9be468825e 903 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 7 854 24.124 T 12-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MIM_c22860 3459eba3998ddf3e75d57b9be468825e 903 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 514 2.0E-154 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MIM_c22860 3459eba3998ddf3e75d57b9be468825e 903 Gene3D G3DSA:3.90.199.10 33 524 5.3E-222 T 12-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 MIM_c22860 3459eba3998ddf3e75d57b9be468825e 903 Gene3D G3DSA:2.120.10.90 543 853 1.0E-122 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal MIM_c22860 3459eba3998ddf3e75d57b9be468825e 903 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 10 853 0.0 T 12-10-2018 MIM_c22860 3459eba3998ddf3e75d57b9be468825e 903 Gene3D G3DSA:1.10.268.10 370 501 5.3E-222 T 12-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MIM_c22860 3459eba3998ddf3e75d57b9be468825e 903 Gene3D G3DSA:3.30.1360.40 236 333 5.3E-222 T 12-10-2018 MIM_c22860 3459eba3998ddf3e75d57b9be468825e 903 SMART SM00434 11 507 2.2E-285 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MIM_c22860 3459eba3998ddf3e75d57b9be468825e 903 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 806 852 3.7E-11 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MIM_c22860 3459eba3998ddf3e75d57b9be468825e 903 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 550 595 5.4E-10 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MIM_c22860 3459eba3998ddf3e75d57b9be468825e 903 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 657 700 2.7E-9 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MIM_c22860 3459eba3998ddf3e75d57b9be468825e 903 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 756 803 4.1E-13 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MIM_c22860 3459eba3998ddf3e75d57b9be468825e 903 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 600 649 3.4E-8 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MIM_c22860 3459eba3998ddf3e75d57b9be468825e 903 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 705 750 2.4E-14 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MIM_c22860 3459eba3998ddf3e75d57b9be468825e 903 SUPERFAMILY SSF101904 545 863 1.29E-110 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal MIM_c22860 3459eba3998ddf3e75d57b9be468825e 903 SUPERFAMILY SSF56719 30 524 5.62E-178 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MIM_c03410 63449b68d513622436ebddd00cd7cfb7 234 SUPERFAMILY SSF51735 5 231 9.92E-62 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c03410 63449b68d513622436ebddd00cd7cfb7 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 7.9E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c03410 63449b68d513622436ebddd00cd7cfb7 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 7.9E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c03410 63449b68d513622436ebddd00cd7cfb7 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 7.9E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c03410 63449b68d513622436ebddd00cd7cfb7 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 231 3.5E-48 T 12-10-2018 MIM_c03410 63449b68d513622436ebddd00cd7cfb7 234 Gene3D G3DSA:3.40.50.720 1 234 6.4E-68 T 12-10-2018 MIM_c03410 63449b68d513622436ebddd00cd7cfb7 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 7.4E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c03410 63449b68d513622436ebddd00cd7cfb7 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 7.4E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c03410 63449b68d513622436ebddd00cd7cfb7 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 7.4E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c03410 63449b68d513622436ebddd00cd7cfb7 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 7.4E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c03410 63449b68d513622436ebddd00cd7cfb7 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 7.4E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c03410 63449b68d513622436ebddd00cd7cfb7 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 7.4E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c22880 92474db5e419756dca71dacab96162e0 241 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 18 236 2.8E-82 T 12-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 MIM_c22880 92474db5e419756dca71dacab96162e0 241 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 18 241 34.399 T 12-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 MIM_c22880 92474db5e419756dca71dacab96162e0 241 Pfam PF13489 Methyltransferase domain 58 210 4.4E-27 T 12-10-2018 MIM_c22880 92474db5e419756dca71dacab96162e0 241 Gene3D G3DSA:3.40.50.150 18 240 5.7E-73 T 12-10-2018 MIM_c22880 92474db5e419756dca71dacab96162e0 241 SUPERFAMILY SSF53335 20 235 1.01E-46 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c38480 f5e3b68eb82b7734a6a9e428769e1127 567 PIRSF PIRSF001294 1 563 3.3E-233 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 MIM_c38480 f5e3b68eb82b7734a6a9e428769e1127 567 Pfam PF03814 Potassium-transporting ATPase A subunit 11 559 1.2E-232 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 MIM_c38480 f5e3b68eb82b7734a6a9e428769e1127 567 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 1 561 33.46 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 MIM_c38480 f5e3b68eb82b7734a6a9e428769e1127 567 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 4 559 1.8E-208 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 MIM_c22740 1a1984d3898bd0d322b228f6a55eb31d 330 Gene3D G3DSA:3.40.50.720 3 322 1.3E-122 T 12-10-2018 MIM_c22740 1a1984d3898bd0d322b228f6a55eb31d 330 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 240 4.6E-44 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MIM_c22740 1a1984d3898bd0d322b228f6a55eb31d 330 Gene3D G3DSA:3.90.25.10 166 309 1.3E-122 T 12-10-2018 MIM_c22740 1a1984d3898bd0d322b228f6a55eb31d 330 SUPERFAMILY SSF51735 2 327 1.07E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c22740 1a1984d3898bd0d322b228f6a55eb31d 330 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 2 327 3.7E-129 T 12-10-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 MIM_c22740 1a1984d3898bd0d322b228f6a55eb31d 330 Hamap MF_01601 ADP-L-glycero-D-manno-heptose-6-epimerase [hldD]. 1 328 49.904 T 12-10-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 MIM_c00700 45d355cee80cc03ff69e1bc7257606aa 258 Gene3D G3DSA:3.30.70.1530 24 95 3.2E-24 T 12-10-2018 MIM_c00700 45d355cee80cc03ff69e1bc7257606aa 258 Pfam PF01514 Secretory protein of YscJ/FliF family 13 190 2.3E-29 T 12-10-2018 IPR006182 Secretory protein YscJ/FliF MIM_c00700 45d355cee80cc03ff69e1bc7257606aa 258 Gene3D G3DSA:3.30.300.30 97 203 1.2E-33 T 12-10-2018 MIM_c00700 45d355cee80cc03ff69e1bc7257606aa 258 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 101 116 5.2E-23 T 12-10-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 MIM_c00700 45d355cee80cc03ff69e1bc7257606aa 258 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 169 181 5.2E-23 T 12-10-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 MIM_c00700 45d355cee80cc03ff69e1bc7257606aa 258 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 29 39 5.2E-23 T 12-10-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 MIM_c00700 45d355cee80cc03ff69e1bc7257606aa 258 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 121 134 5.2E-23 T 12-10-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 MIM_c00700 45d355cee80cc03ff69e1bc7257606aa 258 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 81 94 5.2E-23 T 12-10-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 MIM_c00700 45d355cee80cc03ff69e1bc7257606aa 258 TIGRFAM TIGR02544 III_secr_YscJ: type III secretion apparatus lipoprotein, YscJ/HrcJ family 12 196 1.0E-63 T 12-10-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 MIM_c06730 303e78463c8dfee7f92cf5a0df68a3b7 266 Pfam PF03309 Type III pantothenate kinase 4 201 7.6E-45 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MIM_c06730 303e78463c8dfee7f92cf5a0df68a3b7 266 SUPERFAMILY SSF53067 4 112 9.06E-16 T 12-10-2018 MIM_c06730 303e78463c8dfee7f92cf5a0df68a3b7 266 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 4 227 1.6E-22 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MIM_c06730 303e78463c8dfee7f92cf5a0df68a3b7 266 SUPERFAMILY SSF53067 119 228 7.77E-24 T 12-10-2018 MIM_c06730 303e78463c8dfee7f92cf5a0df68a3b7 266 Gene3D G3DSA:3.30.420.490 120 230 1.2E-54 T 12-10-2018 MIM_c06730 303e78463c8dfee7f92cf5a0df68a3b7 266 Gene3D G3DSA:3.30.420.40 5 119 1.2E-54 T 12-10-2018 MIM_c06730 303e78463c8dfee7f92cf5a0df68a3b7 266 Hamap MF_01274 Type III pantothenate kinase [coaX]. 2 264 16.37 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MIM_c32570 6fdfd581536449c3f4e10a4e68fbfa99 341 SUPERFAMILY SSF51735 15 339 7.33E-86 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c32570 6fdfd581536449c3f4e10a4e68fbfa99 341 PRINTS PR01713 Nucleotide sugar epimerase signature 45 61 9.3E-8 T 12-10-2018 MIM_c32570 6fdfd581536449c3f4e10a4e68fbfa99 341 PRINTS PR01713 Nucleotide sugar epimerase signature 258 273 9.3E-8 T 12-10-2018 MIM_c32570 6fdfd581536449c3f4e10a4e68fbfa99 341 PRINTS PR01713 Nucleotide sugar epimerase signature 234 249 9.3E-8 T 12-10-2018 MIM_c32570 6fdfd581536449c3f4e10a4e68fbfa99 341 PRINTS PR01713 Nucleotide sugar epimerase signature 302 319 9.3E-8 T 12-10-2018 MIM_c32570 6fdfd581536449c3f4e10a4e68fbfa99 341 Gene3D G3DSA:3.90.25.10 194 335 5.5E-116 T 12-10-2018 MIM_c32570 6fdfd581536449c3f4e10a4e68fbfa99 341 Pfam PF01370 NAD dependent epimerase/dehydratase family 19 264 6.4E-56 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MIM_c32570 6fdfd581536449c3f4e10a4e68fbfa99 341 Gene3D G3DSA:3.40.50.720 20 323 5.5E-116 T 12-10-2018 MIM_c25810 0190967f73abcffeca118555ed391e9e 431 Gene3D G3DSA:1.20.1250.20 224 401 5.4E-11 T 12-10-2018 MIM_c25810 0190967f73abcffeca118555ed391e9e 431 SUPERFAMILY SSF103473 6 397 3.4E-25 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c25810 0190967f73abcffeca118555ed391e9e 431 Gene3D G3DSA:1.20.1250.20 2 182 1.3E-11 T 12-10-2018 MIM_c25810 0190967f73abcffeca118555ed391e9e 431 Pfam PF07690 Major Facilitator Superfamily 8 165 6.0E-10 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c25810 0190967f73abcffeca118555ed391e9e 431 Pfam PF07690 Major Facilitator Superfamily 231 397 5.8E-11 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c05170 ae8a806c94106c3549429519dc78c39e 294 PIRSF PIRSF026649 1 294 4.9E-76 T 12-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 MIM_c05170 ae8a806c94106c3549429519dc78c39e 294 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 6 285 1.6E-66 T 12-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 MIM_c27170 ceebbca3e96f828e9c4395f14f85aea4 475 TIGRFAM TIGR03225 benzo_boxB: benzoyl-CoA oxygenase, B subunit 4 474 5.8E-272 T 12-10-2018 IPR017635 Benzoyl-CoA oxygenase, B subunit KEGG: 00362+1.14.13.208|MetaCyc: PWY-1361 MIM_c27170 ceebbca3e96f828e9c4395f14f85aea4 475 Gene3D G3DSA:1.10.620.20 3 475 1.7E-235 T 12-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 MIM_c27170 ceebbca3e96f828e9c4395f14f85aea4 475 SUPERFAMILY SSF47240 107 363 5.81E-51 T 12-10-2018 IPR009078 Ferritin-like superfamily MIM_c09490 4bb16b37bee5d9a8867acfa3a07af54c 374 Pfam PF00529 HlyD membrane-fusion protein of T1SS 295 361 1.6E-8 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MIM_c09490 4bb16b37bee5d9a8867acfa3a07af54c 374 Gene3D G3DSA:2.40.30.170 53 304 2.9E-105 T 12-10-2018 MIM_c09490 4bb16b37bee5d9a8867acfa3a07af54c 374 Gene3D G3DSA:2.40.50.100 65 209 2.9E-105 T 12-10-2018 MIM_c09490 4bb16b37bee5d9a8867acfa3a07af54c 374 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 41 367 9.3E-85 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MIM_c09490 4bb16b37bee5d9a8867acfa3a07af54c 374 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 65 294 3.6E-16 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MIM_c09490 4bb16b37bee5d9a8867acfa3a07af54c 374 Gene3D G3DSA:2.40.420.20 305 367 2.9E-105 T 12-10-2018 MIM_c09490 4bb16b37bee5d9a8867acfa3a07af54c 374 SUPERFAMILY SSF111369 54 299 1.19E-77 T 12-10-2018 MIM_c09490 4bb16b37bee5d9a8867acfa3a07af54c 374 Gene3D G3DSA:1.10.287.470 100 173 2.9E-105 T 12-10-2018 MIM_c24910 8437d78b3ac472e919bd951985feecd5 291 Gene3D G3DSA:1.10.10.10 1 83 1.8E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c24910 8437d78b3ac472e919bd951985feecd5 291 Pfam PF03466 LysR substrate binding domain 85 286 2.5E-29 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c24910 8437d78b3ac472e919bd951985feecd5 291 SUPERFAMILY SSF53850 86 286 6.59E-27 T 12-10-2018 MIM_c24910 8437d78b3ac472e919bd951985feecd5 291 Gene3D G3DSA:3.40.190.10 89 274 6.8E-26 T 12-10-2018 MIM_c24910 8437d78b3ac472e919bd951985feecd5 291 SUPERFAMILY SSF46785 1 109 9.8E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c24910 8437d78b3ac472e919bd951985feecd5 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.9E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c24910 8437d78b3ac472e919bd951985feecd5 291 Gene3D G3DSA:3.40.190.10 170 265 6.8E-26 T 12-10-2018 MIM_c24230 f7a3eb99ce739971617e667589f9ece2 389 Pfam PF13458 Periplasmic binding protein 26 367 4.1E-44 T 12-10-2018 IPR028081 Leucine-binding protein domain MIM_c24230 f7a3eb99ce739971617e667589f9ece2 389 SUPERFAMILY SSF53822 25 384 1.09E-71 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c24230 f7a3eb99ce739971617e667589f9ece2 389 Gene3D G3DSA:3.40.50.2300 29 368 1.7E-110 T 12-10-2018 MIM_c24230 f7a3eb99ce739971617e667589f9ece2 389 Gene3D G3DSA:3.40.50.2300 145 380 1.7E-110 T 12-10-2018 MIM_c35590 87dc583f19750737d0f617100325d73e 133 SUPERFAMILY SSF69118 3 124 7.68E-29 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c35590 87dc583f19750737d0f617100325d73e 133 Pfam PF02627 Carboxymuconolactone decarboxylase family 37 117 2.1E-17 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c35590 87dc583f19750737d0f617100325d73e 133 Gene3D G3DSA:1.20.1290.10 3 127 1.0E-30 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c01610 99272ca3fcb5d807f425eaee6235c264 295 SUPERFAMILY SSF46785 4 113 2.2E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c01610 99272ca3fcb5d807f425eaee6235c264 295 Gene3D G3DSA:1.10.10.10 3 91 1.1E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c01610 99272ca3fcb5d807f425eaee6235c264 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 63 1.0E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c01610 99272ca3fcb5d807f425eaee6235c264 295 Gene3D G3DSA:3.40.190.290 92 294 7.6E-43 T 12-10-2018 MIM_c01610 99272ca3fcb5d807f425eaee6235c264 295 SUPERFAMILY SSF53850 90 293 9.96E-41 T 12-10-2018 MIM_c01610 99272ca3fcb5d807f425eaee6235c264 295 Pfam PF03466 LysR substrate binding domain 89 292 2.2E-41 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c18140 b1abbf6efb81440e522fc765d818691a 371 Pfam PF01594 AI-2E family transporter 15 344 8.8E-53 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like MIM_c15650 b155738c16ec28c65aab05ab45d56b5a 310 Pfam PF05661 Protein of unknown function (DUF808) 14 299 3.2E-106 T 12-10-2018 IPR008526 Inner membrane protein YedI MIM_c15650 b155738c16ec28c65aab05ab45d56b5a 310 PIRSF PIRSF016660 1 35 5.4E-6 T 12-10-2018 IPR008526 Inner membrane protein YedI MIM_c15650 b155738c16ec28c65aab05ab45d56b5a 310 PIRSF PIRSF016660 28 310 2.3E-108 T 12-10-2018 IPR008526 Inner membrane protein YedI MIM_c32680 7cb86c72ba83d503afcb4b18c69bd0cc 351 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 331 4.1E-18 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c36490 83445bcd1951c5099d11aa5237807087 153 Pfam PF12802 MarR family 43 100 6.2E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c36490 83445bcd1951c5099d11aa5237807087 153 Gene3D G3DSA:1.10.10.10 43 105 6.4E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c36490 83445bcd1951c5099d11aa5237807087 153 Gene3D G3DSA:1.10.287.100 111 153 2.9E-11 T 12-10-2018 MIM_c36490 83445bcd1951c5099d11aa5237807087 153 SMART SM00347 36 137 6.1E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c36490 83445bcd1951c5099d11aa5237807087 153 SUPERFAMILY SSF46785 17 150 1.26E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c08090 1cfc5603e8a6e0265b6eb0c6f1b2ca28 396 SUPERFAMILY SSF56935 17 396 5.49E-66 T 12-10-2018 MIM_c08090 1cfc5603e8a6e0265b6eb0c6f1b2ca28 396 PRINTS PR00184 Neisseria sp. porin signature 345 369 1.1E-9 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 MIM_c08090 1cfc5603e8a6e0265b6eb0c6f1b2ca28 396 PRINTS PR00184 Neisseria sp. porin signature 161 178 1.1E-9 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 MIM_c08090 1cfc5603e8a6e0265b6eb0c6f1b2ca28 396 PRINTS PR00184 Neisseria sp. porin signature 60 85 1.1E-9 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 MIM_c08090 1cfc5603e8a6e0265b6eb0c6f1b2ca28 396 Gene3D G3DSA:2.40.160.10 10 396 2.1E-82 T 12-10-2018 IPR023614 Porin domain superfamily MIM_c08090 1cfc5603e8a6e0265b6eb0c6f1b2ca28 396 Pfam PF13609 Gram-negative porin 7 368 1.6E-49 T 12-10-2018 MIM_c32700 4cb761444f617dfe56f64b84fb6814a4 383 Pfam PF13458 Periplasmic binding protein 23 343 5.5E-48 T 12-10-2018 IPR028081 Leucine-binding protein domain MIM_c32700 4cb761444f617dfe56f64b84fb6814a4 383 SUPERFAMILY SSF53822 22 380 1.19E-62 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c32700 4cb761444f617dfe56f64b84fb6814a4 383 Gene3D G3DSA:3.40.50.2300 25 366 1.0E-94 T 12-10-2018 MIM_c32700 4cb761444f617dfe56f64b84fb6814a4 383 Gene3D G3DSA:3.40.50.2300 139 377 1.0E-94 T 12-10-2018 MIM_c11980 2ff191bb76b45b8d8e571b42c2d7fe1a 384 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 378 7.7E-48 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MIM_c11980 2ff191bb76b45b8d8e571b42c2d7fe1a 384 SUPERFAMILY SSF56645 6 243 8.38E-79 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c11980 2ff191bb76b45b8d8e571b42c2d7fe1a 384 Gene3D G3DSA:1.20.140.10 236 383 1.0E-53 T 12-10-2018 MIM_c11980 2ff191bb76b45b8d8e571b42c2d7fe1a 384 Gene3D G3DSA:1.10.540.10 4 119 3.5E-30 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c11980 2ff191bb76b45b8d8e571b42c2d7fe1a 384 PIRSF PIRSF016578 128 368 2.4E-15 T 12-10-2018 MIM_c11980 2ff191bb76b45b8d8e571b42c2d7fe1a 384 PIRSF PIRSF016578 2 83 5.1E-5 T 12-10-2018 MIM_c11980 2ff191bb76b45b8d8e571b42c2d7fe1a 384 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MIM_c11980 2ff191bb76b45b8d8e571b42c2d7fe1a 384 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 217 2.2E-29 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MIM_c11980 2ff191bb76b45b8d8e571b42c2d7fe1a 384 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MIM_c11980 2ff191bb76b45b8d8e571b42c2d7fe1a 384 SUPERFAMILY SSF47203 229 381 2.58E-54 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c11980 2ff191bb76b45b8d8e571b42c2d7fe1a 384 Gene3D G3DSA:2.40.110.10 120 235 3.7E-43 T 12-10-2018 MIM_c11980 2ff191bb76b45b8d8e571b42c2d7fe1a 384 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 8.6E-29 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c37230 093ec04ec51b467ec3db70b4f8070eca 168 Gene3D G3DSA:2.60.120.10 16 168 1.7E-55 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c37230 093ec04ec51b467ec3db70b4f8070eca 168 SUPERFAMILY SSF51182 22 150 1.01E-26 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c37230 093ec04ec51b467ec3db70b4f8070eca 168 Pfam PF12973 ChrR Cupin-like domain 32 120 2.3E-15 T 12-10-2018 IPR025979 ChrR-like cupin domain MIM_c09980 31eac028189de7ec21a47e0d8272fd73 773 TIGRFAM TIGR01785 TonB-hemin: TonB-dependent heme/hemoglobin receptor family protein 62 773 4.2E-116 T 12-10-2018 IPR011276 TonB-dependent haem/haemoglobin receptor GO:0015232|GO:0015886|GO:0019867 MIM_c09980 31eac028189de7ec21a47e0d8272fd73 773 TIGRFAM TIGR01786 TonB-hemlactrns: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein 49 773 4.7E-115 T 12-10-2018 IPR010949 TonB-dependent haemoglobin/transferrin/lactoferrin receptor GO:0019867|GO:0022857|GO:0055085 MIM_c09980 31eac028189de7ec21a47e0d8272fd73 773 SUPERFAMILY SSF56935 54 772 4.76E-75 T 12-10-2018 MIM_c09980 31eac028189de7ec21a47e0d8272fd73 773 Pfam PF00593 TonB dependent receptor 282 769 1.4E-41 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MIM_c09980 31eac028189de7ec21a47e0d8272fd73 773 Gene3D G3DSA:2.40.170.20 174 773 5.1E-86 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MIM_c09980 31eac028189de7ec21a47e0d8272fd73 773 Pfam PF07715 TonB-dependent Receptor Plug Domain 62 148 1.7E-11 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain MIM_c09980 31eac028189de7ec21a47e0d8272fd73 773 Gene3D G3DSA:2.170.130.10 60 173 9.2E-14 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MIM_c08490 b6af18b07a2a901b1112672ad278e83a 240 SMART SM00382 26 212 1.2E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c08490 b6af18b07a2a901b1112672ad278e83a 240 Pfam PF00005 ABC transporter 19 164 2.7E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c08490 b6af18b07a2a901b1112672ad278e83a 240 SUPERFAMILY SSF52540 1 234 2.66E-77 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c08490 b6af18b07a2a901b1112672ad278e83a 240 Gene3D G3DSA:3.40.50.300 1 240 6.5E-79 T 12-10-2018 MIM_c08490 b6af18b07a2a901b1112672ad278e83a 240 PIRSF PIRSF039085 1 240 1.6E-104 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MIM_c08490 b6af18b07a2a901b1112672ad278e83a 240 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c31420 360f800f9ddbc3abe2536044064437dc 320 Gene3D G3DSA:3.40.190.10 125 245 3.3E-94 T 12-10-2018 MIM_c31420 360f800f9ddbc3abe2536044064437dc 320 Gene3D G3DSA:3.40.190.150 28 310 3.3E-94 T 12-10-2018 MIM_c31420 360f800f9ddbc3abe2536044064437dc 320 SUPERFAMILY SSF53850 113 277 6.51E-5 T 12-10-2018 MIM_c31420 360f800f9ddbc3abe2536044064437dc 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 316 9.7E-66 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c31420 360f800f9ddbc3abe2536044064437dc 320 PIRSF PIRSF017082 1 319 1.6E-60 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c33600 32a6ed1324ffa580b129e883c73f3943 140 Pfam PF05656 Protein of unknown function (DUF805) 52 133 3.5E-20 T 12-10-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 MIM_c37640 ed07984f4f04abf40a32f91412bde150 354 Pfam PF13524 Glycosyl transferases group 1 255 343 8.0E-10 T 12-10-2018 MIM_c19380 f6e7c75be1e490209c8437b307842725 295 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 249 275 - T 12-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 MIM_c19380 f6e7c75be1e490209c8437b307842725 295 Pfam PF01148 Cytidylyltransferase family 4 287 2.3E-50 T 12-10-2018 MIM_c40800 6ab383ab637ca72069af8e1d0c53dee3 139 Pfam PF01230 HIT domain 14 109 7.7E-22 T 12-10-2018 IPR001310 Histidine triad (HIT) protein MIM_c40800 6ab383ab637ca72069af8e1d0c53dee3 139 SUPERFAMILY SSF54197 1 137 6.5E-36 T 12-10-2018 IPR036265 HIT-like superfamily MIM_c40800 6ab383ab637ca72069af8e1d0c53dee3 139 PRINTS PR00332 Histidine triad family signature 29 47 1.8E-14 T 12-10-2018 IPR001310 Histidine triad (HIT) protein MIM_c40800 6ab383ab637ca72069af8e1d0c53dee3 139 PRINTS PR00332 Histidine triad family signature 8 24 1.8E-14 T 12-10-2018 IPR001310 Histidine triad (HIT) protein MIM_c40800 6ab383ab637ca72069af8e1d0c53dee3 139 PRINTS PR00332 Histidine triad family signature 96 106 1.8E-14 T 12-10-2018 IPR001310 Histidine triad (HIT) protein MIM_c40800 6ab383ab637ca72069af8e1d0c53dee3 139 Gene3D G3DSA:3.30.428.10 1 138 2.3E-36 T 12-10-2018 IPR036265 HIT-like superfamily MIM_c17770 42adf7fe9444f73a189b667f88c029df 432 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 234 270 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MIM_c17770 42adf7fe9444f73a189b667f88c029df 432 SUPERFAMILY SSF53383 9 416 4.3E-101 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c17770 42adf7fe9444f73a189b667f88c029df 432 Pfam PF00202 Aminotransferase class-III 19 412 1.3E-75 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MIM_c17770 42adf7fe9444f73a189b667f88c029df 432 Gene3D G3DSA:3.90.1150.10 10 409 4.6E-104 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c17770 42adf7fe9444f73a189b667f88c029df 432 PIRSF PIRSF000521 123 158 0.23 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MIM_c17770 42adf7fe9444f73a189b667f88c029df 432 PIRSF PIRSF000521 177 417 1.6E-30 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MIM_c17770 42adf7fe9444f73a189b667f88c029df 432 PIRSF PIRSF000521 4 130 9.7E-6 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MIM_c17770 42adf7fe9444f73a189b667f88c029df 432 Gene3D G3DSA:3.40.640.10 56 317 4.6E-104 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c17770 42adf7fe9444f73a189b667f88c029df 432 TIGRFAM TIGR02407 ectoine_ectB: diaminobutyrate--2-oxoglutarate aminotransferase 4 415 7.3E-202 T 12-10-2018 IPR012773 Ectoine biosynthetic protein GO:0019491|GO:0030170|GO:0047307 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855|MetaCyc: PWY-7988 MIM_c17770 42adf7fe9444f73a189b667f88c029df 432 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 2 420 3.7E-147 T 12-10-2018 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855|MetaCyc: PWY-7988 MIM_c07990 16d8e029369b8ed30de3b604c5861dcb 253 TIGRFAM TIGR00808 malonate_madM: malonate transporter, MadM subunit 2 253 5.3E-127 T 12-10-2018 IPR004691 Malonate/sodium symporter MadM subunit GO:0044668 MIM_c07990 16d8e029369b8ed30de3b604c5861dcb 253 Pfam PF03818 Malonate/sodium symporter MadM subunit 2 60 2.9E-27 T 12-10-2018 IPR018402 Malonate/sodium symporter MadM subunit, N-terminal MIM_c37510 a504a648dd29cde74e28cbba8f29d1e5 278 PIRSF PIRSF015582 1 278 1.1E-73 T 12-10-2018 IPR011206 Citrate lyase beta subunit-like MIM_c37510 a504a648dd29cde74e28cbba8f29d1e5 278 SUPERFAMILY SSF51621 2 229 2.76E-56 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MIM_c37510 a504a648dd29cde74e28cbba8f29d1e5 278 Gene3D G3DSA:3.20.20.60 1 278 5.2E-82 T 12-10-2018 MIM_c37510 a504a648dd29cde74e28cbba8f29d1e5 278 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 3 219 1.7E-42 T 12-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 MIM_c36080 1252a2e03faeef71f277ce431278c4b6 324 PIRSF PIRSF017082 1 324 4.4E-67 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c36080 1252a2e03faeef71f277ce431278c4b6 324 Gene3D G3DSA:3.40.190.10 129 249 1.8E-96 T 12-10-2018 MIM_c36080 1252a2e03faeef71f277ce431278c4b6 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 320 2.6E-69 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c36080 1252a2e03faeef71f277ce431278c4b6 324 Gene3D G3DSA:3.40.190.150 33 314 1.8E-96 T 12-10-2018 MIM_c18950 d41fb4f5b146b789cf785a97c02b3870 380 Gene3D G3DSA:3.30.565.10 192 378 8.6E-33 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c18950 d41fb4f5b146b789cf785a97c02b3870 380 SMART SM00388 127 192 7.2E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MIM_c18950 d41fb4f5b146b789cf785a97c02b3870 380 SUPERFAMILY SSF47384 112 188 5.49E-13 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MIM_c18950 d41fb4f5b146b789cf785a97c02b3870 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 311 325 1.5E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c18950 d41fb4f5b146b789cf785a97c02b3870 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 340 358 1.5E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c18950 d41fb4f5b146b789cf785a97c02b3870 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 329 339 1.5E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c18950 d41fb4f5b146b789cf785a97c02b3870 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 363 376 1.5E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MIM_c18950 d41fb4f5b146b789cf785a97c02b3870 380 SUPERFAMILY SSF55874 187 377 1.18E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MIM_c18950 d41fb4f5b146b789cf785a97c02b3870 380 Pfam PF00512 His Kinase A (phospho-acceptor) domain 131 189 8.4E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MIM_c18950 d41fb4f5b146b789cf785a97c02b3870 380 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 236 378 1.3E-12 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c18950 d41fb4f5b146b789cf785a97c02b3870 380 SMART SM00387 232 379 1.5E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MIM_c18950 d41fb4f5b146b789cf785a97c02b3870 380 Gene3D G3DSA:1.10.287.130 132 188 2.2E-11 T 12-10-2018 MIM_c08660 9a9086e2d274579508af4cbecd58fc0a 264 SUPERFAMILY SSF161098 4 254 3.46E-55 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c08660 9a9086e2d274579508af4cbecd58fc0a 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 254 5.0E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c08660 9a9086e2d274579508af4cbecd58fc0a 264 Gene3D G3DSA:1.10.3720.10 4 264 3.7E-52 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c36790 1e7abeff989e9983e5817e359ee9d1ad 255 Gene3D G3DSA:3.40.50.720 1 255 2.1E-83 T 12-10-2018 MIM_c36790 1e7abeff989e9983e5817e359ee9d1ad 255 SUPERFAMILY SSF51735 8 253 2.42E-80 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c36790 1e7abeff989e9983e5817e359ee9d1ad 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 3.3E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c36790 1e7abeff989e9983e5817e359ee9d1ad 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 3.3E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c36790 1e7abeff989e9983e5817e359ee9d1ad 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 3.3E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c36790 1e7abeff989e9983e5817e359ee9d1ad 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 3.3E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c36790 1e7abeff989e9983e5817e359ee9d1ad 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 3.3E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c36790 1e7abeff989e9983e5817e359ee9d1ad 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 3.3E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c36790 1e7abeff989e9983e5817e359ee9d1ad 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 6.6E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c36790 1e7abeff989e9983e5817e359ee9d1ad 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 6.6E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c36790 1e7abeff989e9983e5817e359ee9d1ad 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 6.6E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c36790 1e7abeff989e9983e5817e359ee9d1ad 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 251 2.4E-61 T 12-10-2018 MIM_c30140 07a82a9cd267ccef2f38a9c5eb18313d 335 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 7 324 7.8E-95 T 12-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MIM_c30140 07a82a9cd267ccef2f38a9c5eb18313d 335 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 7 213 3.0E-42 T 12-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MIM_c20260 d15e1b45adc7d6bbbf07bef266961277 271 SMART SM00382 46 253 6.1E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c20260 d15e1b45adc7d6bbbf07bef266961277 271 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 250 267 1.2E-5 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal MIM_c20260 d15e1b45adc7d6bbbf07bef266961277 271 Gene3D G3DSA:3.40.50.300 16 268 6.6E-58 T 12-10-2018 MIM_c20260 d15e1b45adc7d6bbbf07bef266961277 271 Pfam PF00005 ABC transporter 37 197 1.7E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c20260 d15e1b45adc7d6bbbf07bef266961277 271 SUPERFAMILY SSF52540 21 267 1.94E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c28440 b8d11082add5465e6a9b046291879368 167 SUPERFAMILY SSF52833 1 166 5.72E-31 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c28440 b8d11082add5465e6a9b046291879368 167 Gene3D G3DSA:3.40.30.10 1 167 1.6E-56 T 12-10-2018 MIM_c28440 b8d11082add5465e6a9b046291879368 167 Pfam PF08534 Redoxin 6 163 4.0E-33 T 12-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 MIM_c18090 f26c41f1ddcec8c9b2095fc6a2af7773 141 Gene3D G3DSA:3.40.630.30 40 141 9.5E-18 T 12-10-2018 MIM_c18090 f26c41f1ddcec8c9b2095fc6a2af7773 141 SUPERFAMILY SSF55729 37 141 3.24E-18 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c18090 f26c41f1ddcec8c9b2095fc6a2af7773 141 Pfam PF13508 Acetyltransferase (GNAT) domain 46 120 1.9E-6 T 12-10-2018 IPR000182 GNAT domain MIM_c35790 02a632a018cfe5f4886089d2cc291998 486 SUPERFAMILY SSF51126 10 340 3.9E-31 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor MIM_c35790 02a632a018cfe5f4886089d2cc291998 486 Pfam PF05048 Periplasmic copper-binding protein (NosD) 234 331 5.3E-8 T 12-10-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 MIM_c35790 02a632a018cfe5f4886089d2cc291998 486 Pfam PF05048 Periplasmic copper-binding protein (NosD) 129 228 1.0E-5 T 12-10-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 MIM_c35790 02a632a018cfe5f4886089d2cc291998 486 Gene3D G3DSA:2.160.20.10 21 371 1.7E-12 T 12-10-2018 IPR012334 Pectin lyase fold MIM_c35790 02a632a018cfe5f4886089d2cc291998 486 SMART SM00710 266 286 7100.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat MIM_c35790 02a632a018cfe5f4886089d2cc291998 486 SMART SM00710 136 157 960.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat MIM_c35790 02a632a018cfe5f4886089d2cc291998 486 SMART SM00710 313 372 6300.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat MIM_c35790 02a632a018cfe5f4886089d2cc291998 486 SMART SM00710 193 214 170.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat MIM_c35790 02a632a018cfe5f4886089d2cc291998 486 SMART SM00710 287 308 20.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat MIM_c35790 02a632a018cfe5f4886089d2cc291998 486 SMART SM00710 158 181 12.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat MIM_c35790 02a632a018cfe5f4886089d2cc291998 486 SMART SM00710 244 264 910.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat MIM_c29230 b8844ebaddcc927a8ad2380f67cd1211 209 Pfam PF01161 Phosphatidylethanolamine-binding protein 32 201 1.5E-37 T 12-10-2018 IPR008914 Phosphatidylethanolamine-binding protein MIM_c29230 b8844ebaddcc927a8ad2380f67cd1211 209 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 33 201 1.7E-24 T 12-10-2018 IPR005247 YbhB/YbcL MIM_c29230 b8844ebaddcc927a8ad2380f67cd1211 209 SUPERFAMILY SSF49777 1 203 1.44E-39 T 12-10-2018 IPR036610 PEBP-like superfamily MIM_c29230 b8844ebaddcc927a8ad2380f67cd1211 209 Gene3D G3DSA:3.90.280.10 1 207 1.2E-45 T 12-10-2018 IPR036610 PEBP-like superfamily MIM_c00870 3a269a552221a604b8bf618b99f76cdc 1277 Pfam PF16937 Type III secretion system translocator protein, HrpF 547 723 1.5E-25 T 12-10-2018 IPR031613 Pathogenicity locus protein HrpK MIM_c12360 47a7c5f0bdd241a8e3472ba822206bb2 218 Gene3D G3DSA:3.40.50.850 7 217 1.4E-61 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MIM_c12360 47a7c5f0bdd241a8e3472ba822206bb2 218 Pfam PF00857 Isochorismatase family 9 210 8.4E-23 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 MIM_c12360 47a7c5f0bdd241a8e3472ba822206bb2 218 SUPERFAMILY SSF52499 7 215 2.88E-40 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MIM_c03690 29dfea334c46a3a3cc83239fe07eb148 215 SUPERFAMILY SSF140478 25 182 2.35E-48 T 12-10-2018 IPR023353 LemA-like domain superfamily MIM_c03690 29dfea334c46a3a3cc83239fe07eb148 215 Pfam PF04011 LemA family 10 195 3.3E-59 T 12-10-2018 IPR007156 LemA MIM_c03690 29dfea334c46a3a3cc83239fe07eb148 215 Gene3D G3DSA:1.20.1440.20 17 195 2.3E-56 T 12-10-2018 IPR023353 LemA-like domain superfamily MIM_c29470 1c9cef9d9b3db80cb1171731cb13022d 193 Pfam PF05728 Uncharacterised protein family (UPF0227) 1 190 2.0E-44 T 12-10-2018 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA MIM_c29470 1c9cef9d9b3db80cb1171731cb13022d 193 Gene3D G3DSA:3.40.50.1820 1 193 3.9E-49 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c29470 1c9cef9d9b3db80cb1171731cb13022d 193 SUPERFAMILY SSF53474 2 189 4.46E-15 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c04410 ce17b666774b02e1330ee5dab616512e 328 Gene3D G3DSA:3.40.190.10 129 251 2.0E-92 T 12-10-2018 MIM_c04410 ce17b666774b02e1330ee5dab616512e 328 Gene3D G3DSA:3.40.190.150 33 318 2.0E-92 T 12-10-2018 MIM_c04410 ce17b666774b02e1330ee5dab616512e 328 SUPERFAMILY SSF53850 117 280 4.22E-12 T 12-10-2018 MIM_c04410 ce17b666774b02e1330ee5dab616512e 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 324 2.6E-70 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c04410 ce17b666774b02e1330ee5dab616512e 328 PIRSF PIRSF017082 1 327 1.2E-72 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c20400 25ebaef8cc2c648d1f8860e4b09cdabf 274 Pfam PF12697 Alpha/beta hydrolase family 91 262 1.8E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c20400 25ebaef8cc2c648d1f8860e4b09cdabf 274 SUPERFAMILY SSF53474 3 271 3.12E-20 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c35960 638252d18e0f6cb9b843082672c97701 275 SUPERFAMILY SSF161098 15 266 1.09E-47 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c35960 638252d18e0f6cb9b843082672c97701 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 267 5.4E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c35960 638252d18e0f6cb9b843082672c97701 275 Gene3D G3DSA:1.10.3720.10 13 273 5.0E-52 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c23380 ed07e5edce144de9451ecb4bd6e0c972 317 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 6 285 1.5E-98 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 MIM_c23380 ed07e5edce144de9451ecb4bd6e0c972 317 Pfam PF02401 LytB protein 7 284 3.4E-92 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 MIM_c23380 ed07e5edce144de9451ecb4bd6e0c972 317 Gene3D G3DSA:3.40.1010.20 101 197 8.0E-112 T 12-10-2018 MIM_c23380 ed07e5edce144de9451ecb4bd6e0c972 317 Gene3D G3DSA:3.40.50.11270 16 100 8.0E-112 T 12-10-2018 MIM_c23380 ed07e5edce144de9451ecb4bd6e0c972 317 Gene3D G3DSA:3.40.1010.20 10 283 8.0E-112 T 12-10-2018 MIM_c23380 ed07e5edce144de9451ecb4bd6e0c972 317 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 5 287 37.678 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 MIM_c04930 d1febcf23ad023bd37fd57dcd910b194 232 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 3.1E-15 T 12-10-2018 MIM_c04930 d1febcf23ad023bd37fd57dcd910b194 232 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 3.1E-15 T 12-10-2018 MIM_c04930 d1febcf23ad023bd37fd57dcd910b194 232 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 3.1E-15 T 12-10-2018 MIM_c04930 d1febcf23ad023bd37fd57dcd910b194 232 Pfam PF02416 mttA/Hcf106 family 4 45 6.1E-8 T 12-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 MIM_c04930 d1febcf23ad023bd37fd57dcd910b194 232 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 2 74 2.0E-18 T 12-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 MIM_c04930 d1febcf23ad023bd37fd57dcd910b194 232 Gene3D G3DSA:1.20.120.20 27 150 8.2E-6 T 12-10-2018 MIM_c04930 d1febcf23ad023bd37fd57dcd910b194 232 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 199 16.095 T 12-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 MIM_c01170 9880e0154576b3616135fccd9b3fba11 243 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 216 238 9.4E-11 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal MIM_c01170 9880e0154576b3616135fccd9b3fba11 243 SUPERFAMILY SSF52540 5 238 2.07E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c01170 9880e0154576b3616135fccd9b3fba11 243 SMART SM00382 31 215 9.0E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c01170 9880e0154576b3616135fccd9b3fba11 243 Gene3D G3DSA:3.40.50.300 1 238 2.2E-57 T 12-10-2018 MIM_c01170 9880e0154576b3616135fccd9b3fba11 243 Pfam PF00005 ABC transporter 23 167 9.2E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c06210 3b568ef4c55afbd25aff1aaad375458e 455 Pfam PF12801 4Fe-4S binding domain 65 103 4.8E-11 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MIM_c06210 3b568ef4c55afbd25aff1aaad375458e 455 Pfam PF12801 4Fe-4S binding domain 151 182 6.7E-5 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MIM_c10460 af5079667504e375de37d783cd17715d 136 Pfam PF14903 WG containing repeat 79 102 2.0E-4 T 12-10-2018 IPR032774 WG containing repeat MIM_c10460 af5079667504e375de37d783cd17715d 136 Pfam PF14903 WG containing repeat 41 74 3.8E-4 T 12-10-2018 IPR032774 WG containing repeat MIM_c13520 efa2d6b37a3be740f0e1789c51574e35 255 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 24 253 1.3E-49 T 12-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase MIM_c13520 efa2d6b37a3be740f0e1789c51574e35 255 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 19 252 2.2E-71 T 12-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase MIM_c13520 efa2d6b37a3be740f0e1789c51574e35 255 Gene3D G3DSA:3.60.140.10 2 255 1.3E-78 T 12-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily MIM_c13520 efa2d6b37a3be740f0e1789c51574e35 255 SUPERFAMILY SSF64438 9 254 2.75E-73 T 12-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic MIM_c06670 640f5fb57434d7f77e8efec8cf846e50 292 Pfam PF04228 Putative neutral zinc metallopeptidase 1 289 3.4E-126 T 12-10-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative MIM_c18330 f1053d4c304da3ef3b274943ab83035a 271 Gene3D G3DSA:3.40.50.10090 37 172 2.6E-37 T 12-10-2018 MIM_c18330 f1053d4c304da3ef3b274943ab83035a 271 Gene3D G3DSA:3.40.50.10090 8 234 2.6E-37 T 12-10-2018 MIM_c18330 f1053d4c304da3ef3b274943ab83035a 271 SUPERFAMILY SSF69618 7 229 2.22E-32 T 12-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MIM_c18330 f1053d4c304da3ef3b274943ab83035a 271 Pfam PF02602 Uroporphyrinogen-III synthase HemD 19 234 1.3E-25 T 12-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MIM_c03750 ccfe4035f6d48c9a77ecf90c195a7f74 312 Pfam PF00892 EamA-like transporter family 6 130 1.2E-11 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MIM_c03750 ccfe4035f6d48c9a77ecf90c195a7f74 312 Pfam PF00892 EamA-like transporter family 144 283 3.3E-17 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MIM_c03750 ccfe4035f6d48c9a77ecf90c195a7f74 312 SUPERFAMILY SSF103481 187 287 5.62E-12 T 12-10-2018 MIM_c03750 ccfe4035f6d48c9a77ecf90c195a7f74 312 SUPERFAMILY SSF103481 42 132 2.22E-8 T 12-10-2018 MIM_c35750 91c8ee12b469b0a7038f5c3527959b20 322 Gene3D G3DSA:3.40.50.12260 189 294 3.4E-81 T 12-10-2018 MIM_c35750 91c8ee12b469b0a7038f5c3527959b20 322 Pfam PF01497 Periplasmic binding protein 69 295 2.4E-21 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain MIM_c35750 91c8ee12b469b0a7038f5c3527959b20 322 SUPERFAMILY SSF53807 38 308 3.92E-53 T 12-10-2018 MIM_c35750 91c8ee12b469b0a7038f5c3527959b20 322 Gene3D G3DSA:3.40.50.1980 53 308 3.4E-81 T 12-10-2018 MIM_c17900 20f7808c2fab507cb4fbece0ccfbd976 213 PIRSF PIRSF006170 1 213 1.7E-50 T 12-10-2018 IPR026039 Uncharacterised protein family UPF0070 MIM_c17900 20f7808c2fab507cb4fbece0ccfbd976 213 Pfam PF09976 Tetratricopeptide repeat-like domain 15 211 1.9E-50 T 12-10-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 MIM_c17900 20f7808c2fab507cb4fbece0ccfbd976 213 SUPERFAMILY SSF48452 93 191 5.31E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MIM_c17900 20f7808c2fab507cb4fbece0ccfbd976 213 Gene3D G3DSA:1.25.40.10 32 203 2.2E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MIM_c19710 beaddc24a8e483496a6e3f61b1b11de8 327 SUPERFAMILY SSF103481 197 298 2.35E-12 T 12-10-2018 MIM_c19710 beaddc24a8e483496a6e3f61b1b11de8 327 Pfam PF00892 EamA-like transporter family 159 296 4.6E-14 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MIM_c19710 beaddc24a8e483496a6e3f61b1b11de8 327 Pfam PF00892 EamA-like transporter family 19 148 1.2E-15 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MIM_c19710 beaddc24a8e483496a6e3f61b1b11de8 327 SUPERFAMILY SSF103481 52 150 2.09E-13 T 12-10-2018 MIM_c20600 4bc5490ab3a6a972237f203908a31551 153 SUPERFAMILY SSF54637 5 152 1.96E-39 T 12-10-2018 IPR029069 HotDog domain superfamily MIM_c20600 4bc5490ab3a6a972237f203908a31551 153 Pfam PF01575 MaoC like domain 20 125 1.9E-21 T 12-10-2018 IPR002539 MaoC-like dehydratase domain MIM_c20600 4bc5490ab3a6a972237f203908a31551 153 Gene3D G3DSA:3.10.129.10 2 153 2.7E-46 T 12-10-2018 MIM_c17380 98917bb2c85272a6028794ef91a26e54 300 Gene3D G3DSA:3.40.190.290 94 298 2.0E-41 T 12-10-2018 MIM_c17380 98917bb2c85272a6028794ef91a26e54 300 SUPERFAMILY SSF46785 3 83 2.07E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c17380 98917bb2c85272a6028794ef91a26e54 300 Pfam PF03466 LysR substrate binding domain 90 291 2.2E-41 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c17380 98917bb2c85272a6028794ef91a26e54 300 SUPERFAMILY SSF53850 91 296 2.17E-43 T 12-10-2018 MIM_c17380 98917bb2c85272a6028794ef91a26e54 300 Gene3D G3DSA:1.10.10.10 3 93 2.4E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c17380 98917bb2c85272a6028794ef91a26e54 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.1E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c17380 98917bb2c85272a6028794ef91a26e54 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.1E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c17380 98917bb2c85272a6028794ef91a26e54 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.1E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c17380 98917bb2c85272a6028794ef91a26e54 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 3.2E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c25470 48eb061ea3ea08aebe0d7b4ce63cbff7 656 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 281 294 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MIM_c25470 48eb061ea3ea08aebe0d7b4ce63cbff7 656 SUPERFAMILY SSF53613 15 336 1.2E-71 T 12-10-2018 IPR029056 Ribokinase-like MIM_c25470 48eb061ea3ea08aebe0d7b4ce63cbff7 656 Pfam PF00294 pfkB family carbohydrate kinase 16 329 3.1E-50 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB MIM_c25470 48eb061ea3ea08aebe0d7b4ce63cbff7 656 Gene3D G3DSA:3.20.20.70 348 646 5.6E-42 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c25470 48eb061ea3ea08aebe0d7b4ce63cbff7 656 TIGRFAM TIGR04382 myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase 15 336 4.3E-122 T 12-10-2018 IPR030830 5-Dehydro-2-deoxygluconokinase KEGG: 00562+2.7.1.92 MIM_c25470 48eb061ea3ea08aebe0d7b4ce63cbff7 656 Pfam PF09863 Uncharacterized protein conserved in bacteria (DUF2090) 332 645 2.6E-120 T 12-10-2018 IPR018659 Protein of unknown function DUF2090 MIM_c25470 48eb061ea3ea08aebe0d7b4ce63cbff7 656 Gene3D G3DSA:3.40.1190.20 18 319 2.6E-92 T 12-10-2018 IPR029056 Ribokinase-like MIM_c25470 48eb061ea3ea08aebe0d7b4ce63cbff7 656 Gene3D G3DSA:2.20.150.10 23 118 2.6E-92 T 12-10-2018 IPR023314 5-Dehydro-2-deoxygluconokinase-like superfamily KEGG: 00562+2.7.1.92 MIM_c36180 7d58020dc2e48de16e09ff58045ba78d 208 Gene3D G3DSA:3.40.50.850 1 208 6.3E-60 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MIM_c36180 7d58020dc2e48de16e09ff58045ba78d 208 SUPERFAMILY SSF52499 4 202 8.9E-53 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MIM_c36180 7d58020dc2e48de16e09ff58045ba78d 208 Pfam PF00857 Isochorismatase family 14 165 2.8E-21 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 MIM_c23250 6d6622a4f9f85b9d49f189965944ad5f 337 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 66 92 6.0E-70 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MIM_c23250 6d6622a4f9f85b9d49f189965944ad5f 337 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 207 234 6.0E-70 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MIM_c23250 6d6622a4f9f85b9d49f189965944ad5f 337 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 309 334 6.0E-70 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MIM_c23250 6d6622a4f9f85b9d49f189965944ad5f 337 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 29 56 6.0E-70 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MIM_c23250 6d6622a4f9f85b9d49f189965944ad5f 337 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 150 173 6.0E-70 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MIM_c23250 6d6622a4f9f85b9d49f189965944ad5f 337 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 181 204 6.0E-70 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MIM_c23250 6d6622a4f9f85b9d49f189965944ad5f 337 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 4 335 45.921 T 12-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MIM_c23250 6d6622a4f9f85b9d49f189965944ad5f 337 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 5 196 8.9E-61 T 12-10-2018 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MIM_c23250 6d6622a4f9f85b9d49f189965944ad5f 337 Gene3D G3DSA:3.30.540.10 2 197 1.5E-68 T 12-10-2018 MIM_c23250 6d6622a4f9f85b9d49f189965944ad5f 337 PIRSF PIRSF500210 1 337 3.3E-127 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MIM_c23250 6d6622a4f9f85b9d49f189965944ad5f 337 Gene3D G3DSA:3.40.190.80 198 334 6.5E-54 T 12-10-2018 MIM_c23250 6d6622a4f9f85b9d49f189965944ad5f 337 SUPERFAMILY SSF56655 3 332 4.06E-116 T 12-10-2018 MIM_c23250 6d6622a4f9f85b9d49f189965944ad5f 337 PIRSF PIRSF000904 1 337 2.7E-125 T 12-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MIM_c14830 66bba4458e329deba3f882cf3569c0f3 126 Pfam PF01250 Ribosomal protein S6 3 91 4.6E-29 T 12-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c14830 66bba4458e329deba3f882cf3569c0f3 126 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 21.867 T 12-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 MIM_c14830 66bba4458e329deba3f882cf3569c0f3 126 Gene3D G3DSA:3.30.70.60 1 92 8.7E-33 T 12-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 MIM_c14830 66bba4458e329deba3f882cf3569c0f3 126 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 93 1.3E-34 T 12-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c14830 66bba4458e329deba3f882cf3569c0f3 126 SUPERFAMILY SSF54995 1 103 1.96E-37 T 12-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c23770 489bde7d25e70a5b12671157128dbb09 328 Gene3D G3DSA:3.40.190.150 30 321 2.4E-107 T 12-10-2018 MIM_c23770 489bde7d25e70a5b12671157128dbb09 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 324 4.4E-82 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c23770 489bde7d25e70a5b12671157128dbb09 328 SUPERFAMILY SSF53850 114 289 9.05E-9 T 12-10-2018 MIM_c23770 489bde7d25e70a5b12671157128dbb09 328 PIRSF PIRSF017082 1 328 2.9E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c23770 489bde7d25e70a5b12671157128dbb09 328 Gene3D G3DSA:3.40.190.10 128 251 2.4E-107 T 12-10-2018 MIM_c38100 4e38886aa436205b7d10866f4516ba2e 432 PIRSF PIRSF006066 5 432 3.2E-90 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 MIM_c38100 4e38886aa436205b7d10866f4516ba2e 432 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 11 422 7.9E-82 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit MIM_c38100 4e38886aa436205b7d10866f4516ba2e 432 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 21 428 6.1E-121 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 MIM_c25450 6305a5d18a41abd5d2fe67d29b4516bd 360 SMART SM00922 139 236 1.3E-13 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MIM_c25450 6305a5d18a41abd5d2fe67d29b4516bd 360 Gene3D G3DSA:3.30.390.10 1 122 6.5E-11 T 12-10-2018 IPR029017 Enolase-like, N-terminal MIM_c25450 6305a5d18a41abd5d2fe67d29b4516bd 360 Gene3D G3DSA:3.20.20.120 123 354 1.0E-44 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MIM_c25450 6305a5d18a41abd5d2fe67d29b4516bd 360 SUPERFAMILY SSF51604 126 347 4.98E-38 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MIM_c25450 6305a5d18a41abd5d2fe67d29b4516bd 360 SUPERFAMILY SSF54826 1 121 3.95E-10 T 12-10-2018 MIM_c25450 6305a5d18a41abd5d2fe67d29b4516bd 360 Pfam PF13378 Enolase C-terminal domain-like 142 347 6.1E-27 T 12-10-2018 IPR029065 Enolase C-terminal domain-like MIM_c36090 77c26ca0e5d900ae43ceba80c02a0f3e 498 Gene3D G3DSA:3.30.300.30 397 497 8.8E-25 T 12-10-2018 MIM_c36090 77c26ca0e5d900ae43ceba80c02a0f3e 498 SUPERFAMILY SSF56801 4 497 3.4E-128 T 12-10-2018 MIM_c36090 77c26ca0e5d900ae43ceba80c02a0f3e 498 ProSitePatterns PS00455 Putative AMP-binding domain signature. 156 167 - T 12-10-2018 IPR020845 AMP-binding, conserved site MIM_c36090 77c26ca0e5d900ae43ceba80c02a0f3e 498 Pfam PF13193 AMP-binding enzyme C-terminal domain 410 484 7.7E-9 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MIM_c36090 77c26ca0e5d900ae43ceba80c02a0f3e 498 Gene3D G3DSA:3.40.50.12780 1 396 1.4E-93 T 12-10-2018 MIM_c36090 77c26ca0e5d900ae43ceba80c02a0f3e 498 Pfam PF00501 AMP-binding enzyme 9 401 5.0E-83 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MIM_c30230 ecb9fde8e57c988b4cd2de8792e6bcd2 217 Pfam PF01323 DSBA-like thioredoxin domain 9 186 5.3E-7 T 12-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 MIM_c30230 ecb9fde8e57c988b4cd2de8792e6bcd2 217 SUPERFAMILY SSF52833 1 188 1.53E-25 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c30230 ecb9fde8e57c988b4cd2de8792e6bcd2 217 Gene3D G3DSA:3.40.30.10 1 214 3.1E-46 T 12-10-2018 MIM_c17530 afb6422ce925a0308ea42127cdf16dc9 308 SUPERFAMILY SSF53213 12 280 4.58E-50 T 12-10-2018 MIM_c17530 afb6422ce925a0308ea42127cdf16dc9 308 Gene3D G3DSA:3.40.830.10 1 295 1.9E-78 T 12-10-2018 MIM_c17530 afb6422ce925a0308ea42127cdf16dc9 308 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 7 280 4.6E-70 T 12-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 MIM_c17530 afb6422ce925a0308ea42127cdf16dc9 308 TIGRFAM TIGR02298 HpaD_Fe: 3,4-dihydroxyphenylacetate 2,3-dioxygenase 1 282 7.0E-137 T 12-10-2018 IPR011984 3,4-dihydroxyphenylacetate 2,3-dioxygenase GO:0008687 KEGG: 00350+1.13.11.15 MIM_c08780 194cda9b06c138fe0637f23b07779914 228 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 28 218 3.9E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c08780 194cda9b06c138fe0637f23b07779914 228 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 8 114 3.4E-18 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c08780 194cda9b06c138fe0637f23b07779914 228 Gene3D G3DSA:1.10.3720.10 1 222 5.8E-46 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c08780 194cda9b06c138fe0637f23b07779914 228 SUPERFAMILY SSF161098 7 217 3.01E-37 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c30170 aca7cdd53c92440e4235c07059720749 302 SUPERFAMILY SSF46785 13 116 2.23E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c30170 aca7cdd53c92440e4235c07059720749 302 Gene3D G3DSA:1.10.10.10 9 95 4.8E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c30170 aca7cdd53c92440e4235c07059720749 302 SUPERFAMILY SSF53850 95 298 8.25E-40 T 12-10-2018 MIM_c30170 aca7cdd53c92440e4235c07059720749 302 Gene3D G3DSA:3.40.190.10 97 297 9.7E-62 T 12-10-2018 MIM_c30170 aca7cdd53c92440e4235c07059720749 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 69 6.4E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c30170 aca7cdd53c92440e4235c07059720749 302 Gene3D G3DSA:3.40.190.10 168 269 9.7E-62 T 12-10-2018 MIM_c30170 aca7cdd53c92440e4235c07059720749 302 Pfam PF03466 LysR substrate binding domain 95 298 2.4E-37 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c23210 23cea7746b3f88341a1645730cefa12e 357 Gene3D G3DSA:3.20.20.70 1 350 1.7E-164 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c23210 23cea7746b3f88341a1645730cefa12e 357 PIRSF PIRSF001361 1 352 1.2E-161 T 12-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 MIM_c23210 23cea7746b3f88341a1645730cefa12e 357 SUPERFAMILY SSF51569 7 348 7.01E-137 T 12-10-2018 MIM_c23210 23cea7746b3f88341a1645730cefa12e 357 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 6 349 3.4E-165 T 12-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 MIM_c23210 23cea7746b3f88341a1645730cefa12e 357 Pfam PF00793 DAHP synthetase I family 44 338 4.5E-103 T 12-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MIM_c17040 e328b9d01172489c01b10f39485fe596 396 Gene3D G3DSA:3.30.1540.10 232 324 1.7E-130 T 12-10-2018 MIM_c17040 e328b9d01172489c01b10f39485fe596 396 Gene3D G3DSA:3.40.50.10540 4 385 1.7E-130 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c17040 e328b9d01172489c01b10f39485fe596 396 Pfam PF02515 CoA-transferase family III 5 373 2.1E-128 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 MIM_c17040 e328b9d01172489c01b10f39485fe596 396 SUPERFAMILY SSF89796 3 396 1.44E-130 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c20540 b778ff1d059ce9d65f2189d1f3636514 109 Pfam PF02627 Carboxymuconolactone decarboxylase family 19 97 1.6E-12 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c20540 b778ff1d059ce9d65f2189d1f3636514 109 SUPERFAMILY SSF69118 13 106 6.91E-20 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c20540 b778ff1d059ce9d65f2189d1f3636514 109 Gene3D G3DSA:1.20.1290.10 3 109 7.1E-20 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c04810 bb148199a6b00aa9bc822b53de0fcc59 261 PRINTS PR00164 ABC-2 type transport system membrane protein signature 181 200 1.6E-9 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MIM_c04810 bb148199a6b00aa9bc822b53de0fcc59 261 PRINTS PR00164 ABC-2 type transport system membrane protein signature 201 220 1.6E-9 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MIM_c04810 bb148199a6b00aa9bc822b53de0fcc59 261 PRINTS PR00164 ABC-2 type transport system membrane protein signature 63 85 1.6E-9 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MIM_c04810 bb148199a6b00aa9bc822b53de0fcc59 261 PIRSF PIRSF006648 1 258 9.6E-23 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MIM_c04810 bb148199a6b00aa9bc822b53de0fcc59 261 Pfam PF01061 ABC-2 type transporter 16 224 3.5E-32 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MIM_c11330 4cd4dfbe39223b791b9c3c067ff6fd11 321 SUPERFAMILY SSF53756 6 292 2.54E-32 T 12-10-2018 MIM_c11330 4cd4dfbe39223b791b9c3c067ff6fd11 321 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 142 253 2.2E-15 T 12-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 MIM_c11330 4cd4dfbe39223b791b9c3c067ff6fd11 321 Gene3D G3DSA:3.40.50.2000 134 292 4.4E-22 T 12-10-2018 MIM_c24430 fe2af62d55714c4cd14141afaefcbfcb 628 Gene3D G3DSA:2.60.120.10 2 136 3.6E-15 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c24430 fe2af62d55714c4cd14141afaefcbfcb 628 SUPERFAMILY SSF54631 162 282 1.64E-27 T 12-10-2018 MIM_c24430 fe2af62d55714c4cd14141afaefcbfcb 628 SUPERFAMILY SSF51206 7 131 2.23E-17 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like MIM_c24430 fe2af62d55714c4cd14141afaefcbfcb 628 Pfam PF00027 Cyclic nucleotide-binding domain 36 122 1.4E-8 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain MIM_c24430 fe2af62d55714c4cd14141afaefcbfcb 628 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 486 626 1.5E-38 T 12-10-2018 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding MIM_c24430 fe2af62d55714c4cd14141afaefcbfcb 628 Gene3D G3DSA:3.10.580.10 159 291 2.9E-30 T 12-10-2018 MIM_c24430 fe2af62d55714c4cd14141afaefcbfcb 628 SMART SM00116 236 285 5.3E-7 T 12-10-2018 IPR000644 CBS domain MIM_c24430 fe2af62d55714c4cd14141afaefcbfcb 628 SMART SM00116 171 219 1.2E-7 T 12-10-2018 IPR000644 CBS domain MIM_c24430 fe2af62d55714c4cd14141afaefcbfcb 628 Pfam PF00571 CBS domain 231 283 3.1E-10 T 12-10-2018 IPR000644 CBS domain MIM_c24430 fe2af62d55714c4cd14141afaefcbfcb 628 Pfam PF00571 CBS domain 166 218 1.4E-9 T 12-10-2018 IPR000644 CBS domain MIM_c24430 fe2af62d55714c4cd14141afaefcbfcb 628 Pfam PF03445 Putative nucleotidyltransferase DUF294 310 449 3.6E-46 T 12-10-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 MIM_c37750 9b1549d436381096d5b337514ebd90fd 428 Gene3D G3DSA:3.40.50.1820 110 269 2.1E-5 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c37750 9b1549d436381096d5b337514ebd90fd 428 SUPERFAMILY SSF53474 119 263 2.83E-6 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c35740 3c09d23e0793b62212b41ef71a3d6b09 664 Pfam PF00593 TonB dependent receptor 219 663 7.7E-66 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MIM_c35740 3c09d23e0793b62212b41ef71a3d6b09 664 SUPERFAMILY SSF56935 54 664 2.66E-132 T 12-10-2018 MIM_c35740 3c09d23e0793b62212b41ef71a3d6b09 664 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 647 664 - T 12-10-2018 IPR010917 TonB-dependent receptor, conserved site MIM_c35740 3c09d23e0793b62212b41ef71a3d6b09 664 Pfam PF07715 TonB-dependent Receptor Plug Domain 66 175 1.2E-27 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain MIM_c35740 3c09d23e0793b62212b41ef71a3d6b09 664 Gene3D G3DSA:2.40.170.20 186 664 1.0E-149 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MIM_c35740 3c09d23e0793b62212b41ef71a3d6b09 664 Gene3D G3DSA:2.170.130.10 49 180 8.9E-41 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MIM_c02660 5b5325b37674bec7cd10d9fe2e16311c 285 SUPERFAMILY SSF161098 89 272 1.26E-39 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c02660 5b5325b37674bec7cd10d9fe2e16311c 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 268 6.4E-25 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c02660 5b5325b37674bec7cd10d9fe2e16311c 285 Gene3D G3DSA:1.10.3720.10 85 277 2.0E-32 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c34600 2f0c3c2f6c3ca1ae604536b7f230bddf 413 Pfam PF06224 Winged helix DNA-binding domain 44 388 5.9E-80 T 12-10-2018 IPR009351 Protein of unknown function DUF1006 MIM_c01160 34bf0fe1cf0960f0c854b9832b7daa0f 326 Pfam PF02653 Branched-chain amino acid transport system / permease component 31 300 3.0E-37 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c04210 7931cc4d80eb48120981eedf71a3e0f4 326 Gene3D G3DSA:3.40.50.880 2 203 4.6E-45 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c04210 7931cc4d80eb48120981eedf71a3e0f4 326 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 269 311 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MIM_c04210 7931cc4d80eb48120981eedf71a3e0f4 326 Pfam PF12833 Helix-turn-helix domain 238 317 6.4E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c04210 7931cc4d80eb48120981eedf71a3e0f4 326 Pfam PF01965 DJ-1/PfpI family 74 176 1.0E-12 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 MIM_c04210 7931cc4d80eb48120981eedf71a3e0f4 326 Gene3D G3DSA:1.10.10.60 217 320 9.4E-27 T 12-10-2018 MIM_c04210 7931cc4d80eb48120981eedf71a3e0f4 326 SUPERFAMILY SSF46689 217 266 1.15E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c04210 7931cc4d80eb48120981eedf71a3e0f4 326 SUPERFAMILY SSF46689 268 318 2.51E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c04210 7931cc4d80eb48120981eedf71a3e0f4 326 SMART SM00342 232 315 1.1E-25 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c04210 7931cc4d80eb48120981eedf71a3e0f4 326 SUPERFAMILY SSF52317 2 196 1.46E-38 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c16300 e94a449fb05e82f2c8e2e8e0d294322f 291 Pfam PF00482 Type II secretion system (T2SS), protein F 154 278 9.6E-15 T 12-10-2018 IPR018076 Type II secretion system F domain MIM_c12600 41ad7a8e01fd6e81b3406043b5273faf 319 SUPERFAMILY SSF52096 5 315 5.62E-101 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c12600 41ad7a8e01fd6e81b3406043b5273faf 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 88 99 1.6E-45 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MIM_c12600 41ad7a8e01fd6e81b3406043b5273faf 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 197 206 1.6E-45 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MIM_c12600 41ad7a8e01fd6e81b3406043b5273faf 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 113 131 1.6E-45 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MIM_c12600 41ad7a8e01fd6e81b3406043b5273faf 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 169 182 1.6E-45 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MIM_c12600 41ad7a8e01fd6e81b3406043b5273faf 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 153 166 1.6E-45 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MIM_c12600 41ad7a8e01fd6e81b3406043b5273faf 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 134 150 1.6E-45 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MIM_c12600 41ad7a8e01fd6e81b3406043b5273faf 319 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 5 316 49.196 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MIM_c12600 41ad7a8e01fd6e81b3406043b5273faf 319 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 6 148 1.2E-65 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MIM_c12600 41ad7a8e01fd6e81b3406043b5273faf 319 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 317 2.0E-147 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MIM_c12600 41ad7a8e01fd6e81b3406043b5273faf 319 Gene3D G3DSA:3.90.226.10 1 317 1.4E-117 T 12-10-2018 MIM_c13460 60e63486b4ba58fb7d727c3ad84216ec 311 Gene3D G3DSA:3.20.20.70 9 302 1.4E-22 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c13460 60e63486b4ba58fb7d727c3ad84216ec 311 SMART SM01130 10 303 7.2E-6 T 12-10-2018 IPR002220 DapA-like GO:0016829 MIM_c13460 60e63486b4ba58fb7d727c3ad84216ec 311 SUPERFAMILY SSF51569 14 298 3.56E-24 T 12-10-2018 MIM_c33660 91191ae1cb133ef598354c0a7789195f 464 SUPERFAMILY SSF51905 3 346 6.28E-52 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c33660 91191ae1cb133ef598354c0a7789195f 464 Pfam PF01494 FAD binding domain 3 341 8.7E-49 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 MIM_c33660 91191ae1cb133ef598354c0a7789195f 464 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.9E-26 T 12-10-2018 MIM_c33660 91191ae1cb133ef598354c0a7789195f 464 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 1.9E-26 T 12-10-2018 MIM_c33660 91191ae1cb133ef598354c0a7789195f 464 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 313 1.9E-26 T 12-10-2018 MIM_c33660 91191ae1cb133ef598354c0a7789195f 464 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 297 1.9E-26 T 12-10-2018 MIM_c33660 91191ae1cb133ef598354c0a7789195f 464 Gene3D G3DSA:3.30.70.2450 179 271 1.9E-74 T 12-10-2018 MIM_c33660 91191ae1cb133ef598354c0a7789195f 464 Gene3D G3DSA:3.50.50.60 5 340 1.9E-74 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c26020 0b23b3892e32b5c428606de81f3c5f0f 196 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 14 89 7.0E-20 T 12-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 MIM_c26020 0b23b3892e32b5c428606de81f3c5f0f 196 SMART SM01103 6 89 1.2E-34 T 12-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 MIM_c26020 0b23b3892e32b5c428606de81f3c5f0f 196 Gene3D G3DSA:3.30.110.60 4 107 2.1E-28 T 12-10-2018 IPR035920 YhbY-like superfamily MIM_c26020 0b23b3892e32b5c428606de81f3c5f0f 196 Pfam PF01985 CRS1 / YhbY (CRM) domain 6 89 9.2E-17 T 12-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 MIM_c26020 0b23b3892e32b5c428606de81f3c5f0f 196 SUPERFAMILY SSF75471 5 96 8.89E-24 T 12-10-2018 IPR035920 YhbY-like superfamily MIM_c23640 e56f01d4bd8b80758cf8d33a3d20c679 221 SUPERFAMILY SSF46689 4 78 5.13E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c23640 e56f01d4bd8b80758cf8d33a3d20c679 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 2.4E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c23640 e56f01d4bd8b80758cf8d33a3d20c679 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 2.4E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c23640 e56f01d4bd8b80758cf8d33a3d20c679 221 SUPERFAMILY SSF48498 86 219 1.02E-29 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MIM_c23640 e56f01d4bd8b80758cf8d33a3d20c679 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 8.0E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c23640 e56f01d4bd8b80758cf8d33a3d20c679 221 Gene3D G3DSA:1.10.357.10 11 218 6.5E-61 T 12-10-2018 MIM_c23640 e56f01d4bd8b80758cf8d33a3d20c679 221 ProSitePatterns PS01081 TetR-type HTH domain signature. 25 56 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MIM_24p00110 218f06748a333ad9392ec9a57a64a37f 330 Gene3D G3DSA:3.40.190.10 131 255 8.9E-82 T 12-10-2018 MIM_24p00110 218f06748a333ad9392ec9a57a64a37f 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 326 6.2E-58 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_24p00110 218f06748a333ad9392ec9a57a64a37f 330 PIRSF PIRSF017082 1 330 4.7E-63 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_24p00110 218f06748a333ad9392ec9a57a64a37f 330 Gene3D G3DSA:3.40.190.150 33 315 8.9E-82 T 12-10-2018 MIM_24p00110 218f06748a333ad9392ec9a57a64a37f 330 SUPERFAMILY SSF53850 119 295 2.55E-7 T 12-10-2018 MIM_c00120 c2bcde146e025a83ba299201cbfe0324 136 SUPERFAMILY SSF52038 10 76 6.67E-9 T 12-10-2018 IPR035905 Barstar-like superfamily MIM_c00120 c2bcde146e025a83ba299201cbfe0324 136 Pfam PF01337 Barstar (barnase inhibitor) 12 81 7.2E-6 T 12-10-2018 IPR000468 Barstar (barnase inhibitor) MIM_c27760 9b1ed49535dd0c06acf33ba89aadb448 746 Gene3D G3DSA:1.10.3810.10 65 261 2.1E-41 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c27760 9b1ed49535dd0c06acf33ba89aadb448 746 TIGRFAM TIGR02073 PBP_1c: penicillin-binding protein 1C 54 631 8.2E-179 T 12-10-2018 IPR011815 Penicillin-binding protein 1C GO:0008955|GO:0009252 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c27760 9b1ed49535dd0c06acf33ba89aadb448 746 Gene3D G3DSA:3.40.710.10 280 640 1.2E-83 T 12-10-2018 MIM_c27760 9b1ed49535dd0c06acf33ba89aadb448 746 SUPERFAMILY SSF53955 61 245 1.15E-43 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily MIM_c27760 9b1ed49535dd0c06acf33ba89aadb448 746 Pfam PF00912 Transglycosylase 81 238 8.4E-44 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c27760 9b1ed49535dd0c06acf33ba89aadb448 746 Pfam PF06832 Penicillin-Binding Protein C-terminus Family 647 731 3.4E-16 T 12-10-2018 IPR009647 Penicillin-binding, C-terminal KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MIM_c27760 9b1ed49535dd0c06acf33ba89aadb448 746 SUPERFAMILY SSF56601 233 634 5.83E-86 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MIM_c27760 9b1ed49535dd0c06acf33ba89aadb448 746 Pfam PF00905 Penicillin binding protein transpeptidase domain 327 576 6.6E-15 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MIM_c15450 f82ef2caba93fbdb46d7a87ba3f1cd3e 320 SUPERFAMILY SSF52283 6 139 9.78E-29 T 12-10-2018 MIM_c15450 f82ef2caba93fbdb46d7a87ba3f1cd3e 320 Gene3D G3DSA:3.40.50.720 22 318 1.8E-111 T 12-10-2018 MIM_c15450 f82ef2caba93fbdb46d7a87ba3f1cd3e 320 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 290 2.8E-55 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MIM_c15450 f82ef2caba93fbdb46d7a87ba3f1cd3e 320 Gene3D G3DSA:3.40.50.720 100 289 1.8E-111 T 12-10-2018 MIM_c15450 f82ef2caba93fbdb46d7a87ba3f1cd3e 320 SUPERFAMILY SSF51735 104 291 6.49E-53 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c15450 f82ef2caba93fbdb46d7a87ba3f1cd3e 320 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 197 219 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MIM_c15450 f82ef2caba93fbdb46d7a87ba3f1cd3e 320 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 226 242 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MIM_c15450 f82ef2caba93fbdb46d7a87ba3f1cd3e 320 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 24 316 2.6E-23 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 MIM_c27480 8a353cb476c04322969c2ecc65eaa2ce 430 Gene3D G3DSA:3.50.50.60 34 387 5.4E-76 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c27480 8a353cb476c04322969c2ecc65eaa2ce 430 Gene3D G3DSA:3.30.9.10 127 349 5.4E-76 T 12-10-2018 MIM_c27480 8a353cb476c04322969c2ecc65eaa2ce 430 SUPERFAMILY SSF51905 33 417 7.22E-49 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c27480 8a353cb476c04322969c2ecc65eaa2ce 430 Pfam PF01266 FAD dependent oxidoreductase 34 386 8.1E-57 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MIM_c28530 dde79fba80a6c9486c93a8b8417575bd 183 Gene3D G3DSA:3.40.30.10 96 183 3.3E-21 T 12-10-2018 MIM_c28530 dde79fba80a6c9486c93a8b8417575bd 183 SUPERFAMILY SSF52833 41 177 6.15E-44 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c28530 dde79fba80a6c9486c93a8b8417575bd 183 PIRSF PIRSF000216 11 182 1.5E-43 T 12-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c28530 dde79fba80a6c9486c93a8b8417575bd 183 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 45 175 1.5E-39 T 12-10-2018 MIM_c28530 dde79fba80a6c9486c93a8b8417575bd 183 Gene3D G3DSA:1.10.10.1590 33 95 1.6E-13 T 12-10-2018 MIM_c25670 330d77c804ce301115e33378b20e988a 169 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 163 6.3E-22 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MIM_c25670 330d77c804ce301115e33378b20e988a 169 SUPERFAMILY SSF88659 91 165 3.36E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MIM_c25670 330d77c804ce301115e33378b20e988a 169 Pfam PF04542 Sigma-70 region 2 13 74 1.4E-7 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MIM_c25670 330d77c804ce301115e33378b20e988a 169 Pfam PF08281 Sigma-70, region 4 107 159 8.9E-14 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MIM_c25670 330d77c804ce301115e33378b20e988a 169 Gene3D G3DSA:1.10.1740.10 5 76 1.8E-5 T 12-10-2018 MIM_c25670 330d77c804ce301115e33378b20e988a 169 SUPERFAMILY SSF88946 11 95 1.37E-10 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MIM_c25670 330d77c804ce301115e33378b20e988a 169 Gene3D G3DSA:1.10.10.10 81 166 8.4E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c04980 a85155569e546bf66b9481c251e2003a 214 Gene3D G3DSA:2.102.10.10 58 208 8.8E-46 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MIM_c04980 a85155569e546bf66b9481c251e2003a 214 Pfam PF00355 Rieske [2Fe-2S] domain 129 193 1.6E-10 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MIM_c04980 a85155569e546bf66b9481c251e2003a 214 Pfam PF10399 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal 23 55 2.0E-7 T 12-10-2018 IPR019470 Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signal GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 MIM_c04980 a85155569e546bf66b9481c251e2003a 214 SUPERFAMILY SSF50022 45 208 2.32E-41 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MIM_c04980 a85155569e546bf66b9481c251e2003a 214 PRINTS PR00162 Rieske 2Fe-2S subunit signature 135 146 2.0E-7 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 MIM_c04980 a85155569e546bf66b9481c251e2003a 214 PRINTS PR00162 Rieske 2Fe-2S subunit signature 167 179 2.0E-7 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 MIM_c04980 a85155569e546bf66b9481c251e2003a 214 PRINTS PR00162 Rieske 2Fe-2S subunit signature 180 192 2.0E-7 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 MIM_c04980 a85155569e546bf66b9481c251e2003a 214 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 25 208 6.9E-62 T 12-10-2018 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 MIM_c11660 e25a0c1dd2c7ac57b256a02307d1416e 122 Pfam PF00034 Cytochrome c 27 111 1.4E-10 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c11660 e25a0c1dd2c7ac57b256a02307d1416e 122 Gene3D G3DSA:1.10.760.10 23 115 1.7E-18 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c11660 e25a0c1dd2c7ac57b256a02307d1416e 122 SUPERFAMILY SSF46626 6 115 3.25E-18 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c08060 bf24c835c6bbde6e8b85e4fd9f8d2de9 343 Gene3D G3DSA:3.40.50.300 24 343 3.5E-93 T 12-10-2018 MIM_c08060 bf24c835c6bbde6e8b85e4fd9f8d2de9 343 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 254 340 8.2E-24 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c08060 bf24c835c6bbde6e8b85e4fd9f8d2de9 343 ProSitePatterns PS00211 ABC transporters family signature. 177 191 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c08060 bf24c835c6bbde6e8b85e4fd9f8d2de9 343 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 256 320 1.1E-14 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MIM_c08060 bf24c835c6bbde6e8b85e4fd9f8d2de9 343 SMART SM00382 55 254 3.7E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c08060 bf24c835c6bbde6e8b85e4fd9f8d2de9 343 Pfam PF00005 ABC transporter 47 204 7.6E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c08060 bf24c835c6bbde6e8b85e4fd9f8d2de9 343 SUPERFAMILY SSF52540 27 275 2.08E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c07320 bb61ab980304e4f8a62342e6b031603b 251 Gene3D G3DSA:1.10.10.10 8 74 4.4E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c07320 bb61ab980304e4f8a62342e6b031603b 251 SUPERFAMILY SSF55781 79 246 1.18E-31 T 12-10-2018 MIM_c07320 bb61ab980304e4f8a62342e6b031603b 251 SUPERFAMILY SSF46785 10 76 1.2E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c07320 bb61ab980304e4f8a62342e6b031603b 251 Gene3D G3DSA:3.30.450.40 75 242 2.6E-41 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c07320 bb61ab980304e4f8a62342e6b031603b 251 Pfam PF09339 IclR helix-turn-helix domain 10 56 7.4E-8 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c07320 bb61ab980304e4f8a62342e6b031603b 251 Pfam PF01614 Bacterial transcriptional regulator 128 242 6.3E-17 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal MIM_c07320 bb61ab980304e4f8a62342e6b031603b 251 SMART SM00346 7 95 9.4E-4 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MIM_c40370 72b9823c2ca7b75f2eb7cd556b27f464 83 Gene3D G3DSA:1.10.1200.10 3 83 1.0E-15 T 12-10-2018 IPR036736 ACP-like superfamily MIM_c40370 72b9823c2ca7b75f2eb7cd556b27f464 83 ProSitePatterns PS00012 Phosphopantetheine attachment site. 35 50 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site MIM_c40370 72b9823c2ca7b75f2eb7cd556b27f464 83 SUPERFAMILY SSF47336 3 80 1.7E-15 T 12-10-2018 IPR036736 ACP-like superfamily MIM_c40370 72b9823c2ca7b75f2eb7cd556b27f464 83 Pfam PF00550 Phosphopantetheine attachment site 10 75 1.8E-8 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain MIM_c24440 7e5821dc5035e4fdb3cd9d6a0a43e1b3 237 Gene3D G3DSA:3.30.420.10 37 218 2.4E-32 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MIM_c24440 7e5821dc5035e4fdb3cd9d6a0a43e1b3 237 Pfam PF00929 Exonuclease 46 206 1.5E-21 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MIM_c24440 7e5821dc5035e4fdb3cd9d6a0a43e1b3 237 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 42 217 5.6E-21 T 12-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MIM_c24440 7e5821dc5035e4fdb3cd9d6a0a43e1b3 237 SMART SM00479 44 215 2.5E-20 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MIM_c24440 7e5821dc5035e4fdb3cd9d6a0a43e1b3 237 SUPERFAMILY SSF53098 38 217 1.37E-38 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily MIM_c23690 ca0dae23c1f59071200eca1ca11932bd 192 Pfam PF16036 Chalcone isomerase-like 24 190 7.8E-44 T 12-10-2018 IPR016087 Chalcone isomerase GO:0016872 MIM_c23690 ca0dae23c1f59071200eca1ca11932bd 192 SUPERFAMILY SSF54626 23 189 2.35E-20 T 12-10-2018 IPR036298 Chalcone isomerase superfamily GO:0016872 MIM_c23690 ca0dae23c1f59071200eca1ca11932bd 192 Gene3D G3DSA:3.50.70.10 26 174 2.0E-19 T 12-10-2018 IPR016088 Chalcone isomerase, 3-layer sandwich KEGG: 00941+5.5.1.6|MetaCyc: PWY-2002|MetaCyc: PWY-5059|MetaCyc: PWY-6325|MetaCyc: PWY-6787|MetaCyc: PWY-7397|MetaCyc: PWY-7897 MIM_c23780 ee275719ace99ddf7a40ef7c9724d4a1 565 TIGRFAM TIGR02231 TIGR02231: conserved hypothetical protein 55 561 1.4E-110 T 12-10-2018 IPR011935 Conserved hypothetical protein CHP02231 MIM_c23780 ee275719ace99ddf7a40ef7c9724d4a1 565 Pfam PF13600 N-terminal domain of unknown function (DUF4140) 58 158 1.3E-21 T 12-10-2018 IPR025554 Domain of unknown function DUF4140 MIM_c23780 ee275719ace99ddf7a40ef7c9724d4a1 565 Pfam PF13598 Domain of unknown function (DUF4139) 249 557 5.0E-56 T 12-10-2018 IPR037291 Domain of unknown function DUF4139 MIM_c26480 3532ecb425b5c5f19fdad57d4a517f92 387 Gene3D G3DSA:3.30.1540.10 227 318 1.1E-130 T 12-10-2018 MIM_c26480 3532ecb425b5c5f19fdad57d4a517f92 387 Gene3D G3DSA:3.40.50.10540 7 337 1.1E-130 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c26480 3532ecb425b5c5f19fdad57d4a517f92 387 Pfam PF02515 CoA-transferase family III 7 373 1.8E-127 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 MIM_c26480 3532ecb425b5c5f19fdad57d4a517f92 387 SUPERFAMILY SSF89796 6 379 1.96E-131 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c25140 9465f0a8f085ee9f2045adc3c024d26e 354 SUPERFAMILY SSF56235 29 325 3.16E-100 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MIM_c25140 9465f0a8f085ee9f2045adc3c024d26e 354 Gene3D G3DSA:3.60.60.10 29 354 2.4E-130 T 12-10-2018 MIM_c25140 9465f0a8f085ee9f2045adc3c024d26e 354 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 29 314 2.0E-47 T 12-10-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal MIM_c20070 65bf80d86306b74e9324a9e598ec6368 528 Gene3D G3DSA:3.40.605.10 44 523 2.1E-205 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c20070 65bf80d86306b74e9324a9e598ec6368 528 Gene3D G3DSA:3.40.309.10 269 458 2.1E-205 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MIM_c20070 65bf80d86306b74e9324a9e598ec6368 528 Pfam PF00171 Aldehyde dehydrogenase family 23 470 1.3E-47 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c20070 65bf80d86306b74e9324a9e598ec6368 528 SUPERFAMILY SSF53720 23 521 5.11E-101 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c33500 c099c5560142e77de6331f089783d593 486 SUPERFAMILY SSF53720 9 483 5.5E-154 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c33500 c099c5560142e77de6331f089783d593 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MIM_c33500 c099c5560142e77de6331f089783d593 486 Gene3D G3DSA:3.40.605.10 22 481 3.0E-163 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c33500 c099c5560142e77de6331f089783d593 486 Pfam PF00171 Aldehyde dehydrogenase family 17 482 3.2E-164 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c33500 c099c5560142e77de6331f089783d593 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MIM_c33500 c099c5560142e77de6331f089783d593 486 Gene3D G3DSA:3.40.309.10 256 453 3.0E-163 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MIM_c14950 0cc02e7fc64774a32b8609e66394b190 409 Pfam PF05940 NnrS protein 15 390 1.3E-91 T 12-10-2018 IPR010266 NnrS MIM_c40390 8d165c14c6d40be727040620c07a89c0 630 SUPERFAMILY SSF54637 530 625 7.79E-11 T 12-10-2018 IPR029069 HotDog domain superfamily MIM_c40390 8d165c14c6d40be727040620c07a89c0 630 Gene3D G3DSA:3.30.300.30 361 483 1.1E-10 T 12-10-2018 MIM_c40390 8d165c14c6d40be727040620c07a89c0 630 Gene3D G3DSA:3.40.50.12780 12 327 1.2E-23 T 12-10-2018 MIM_c40390 8d165c14c6d40be727040620c07a89c0 630 SUPERFAMILY SSF56801 28 466 1.7E-47 T 12-10-2018 MIM_c40390 8d165c14c6d40be727040620c07a89c0 630 Pfam PF00501 AMP-binding enzyme 29 306 1.2E-14 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MIM_c40390 8d165c14c6d40be727040620c07a89c0 630 Gene3D G3DSA:3.10.129.10 519 630 4.0E-27 T 12-10-2018 MIM_c22630 50269322e31561e17283fa103e9fb972 639 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 292 3.7E-39 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c22630 50269322e31561e17283fa103e9fb972 639 Pfam PF02653 Branched-chain amino acid transport system / permease component 352 607 6.5E-39 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c08270 8cf7681b2c99650dbfac8596f7aed8ee 392 Gene3D G3DSA:1.20.1250.20 197 391 1.6E-26 T 12-10-2018 MIM_c08270 8cf7681b2c99650dbfac8596f7aed8ee 392 Gene3D G3DSA:1.20.1250.20 1 184 1.5E-17 T 12-10-2018 MIM_c08270 8cf7681b2c99650dbfac8596f7aed8ee 392 Pfam PF07690 Major Facilitator Superfamily 15 351 2.4E-36 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c08270 8cf7681b2c99650dbfac8596f7aed8ee 392 SUPERFAMILY SSF103473 2 390 1.57E-52 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c15910 8b000753f342bb56d79eae9993116830 218 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 33 193 9.1E-31 T 12-10-2018 IPR005586 ABC-type transport auxiliary lipoprotein component MIM_c15910 8b000753f342bb56d79eae9993116830 218 SUPERFAMILY SSF159594 30 196 7.85E-22 T 12-10-2018 MIM_c20300 54d2d812d502e3003e40cad72f36ea64 455 SUPERFAMILY SSF103378 4 438 6.41E-104 T 12-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 MIM_c20300 54d2d812d502e3003e40cad72f36ea64 455 Pfam PF03972 MmgE/PrpD family 5 430 1.9E-110 T 12-10-2018 IPR005656 MmgE/PrpD GO:0016829 MIM_c20300 54d2d812d502e3003e40cad72f36ea64 455 Gene3D G3DSA:1.10.4100.10 3 261 1.6E-70 T 12-10-2018 MIM_c20300 54d2d812d502e3003e40cad72f36ea64 455 Gene3D G3DSA:3.30.1330.120 265 396 4.0E-32 T 12-10-2018 MIM_c15110 5f68052319274e0a590f4e7f31fc12fc 266 Gene3D G3DSA:1.10.3720.10 5 266 7.6E-48 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c15110 5f68052319274e0a590f4e7f31fc12fc 266 SUPERFAMILY SSF161098 6 263 2.62E-53 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c15110 5f68052319274e0a590f4e7f31fc12fc 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 261 5.1E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c21260 1748ff503776163d43cac81478001e51 264 Pfam PF00005 ABC transporter 22 177 1.6E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c21260 1748ff503776163d43cac81478001e51 264 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c21260 1748ff503776163d43cac81478001e51 264 SUPERFAMILY SSF52540 1 231 5.64E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c21260 1748ff503776163d43cac81478001e51 264 SMART SM00382 31 226 2.9E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c21260 1748ff503776163d43cac81478001e51 264 Gene3D G3DSA:3.40.50.300 1 258 2.7E-55 T 12-10-2018 MIM_c21010 3acf669464578241246e0f881053d33f 240 PRINTS PR00096 Glutamine amidotransferase superfamily signature 183 196 5.7E-5 T 12-10-2018 MIM_c21010 3acf669464578241246e0f881053d33f 240 PRINTS PR00096 Glutamine amidotransferase superfamily signature 92 103 5.7E-5 T 12-10-2018 MIM_c21010 3acf669464578241246e0f881053d33f 240 Gene3D G3DSA:3.40.50.880 17 238 8.6E-49 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c21010 3acf669464578241246e0f881053d33f 240 SUPERFAMILY SSF52317 34 235 9.17E-36 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like MIM_c21010 3acf669464578241246e0f881053d33f 240 Pfam PF00117 Glutamine amidotransferase class-I 35 196 1.4E-18 T 12-10-2018 IPR017926 Glutamine amidotransferase MIM_c24900 7d2de3e7913eb44af8346633d46027df 382 SUPERFAMILY SSF103473 8 379 2.62E-21 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c24900 7d2de3e7913eb44af8346633d46027df 382 Gene3D G3DSA:1.20.1250.20 14 195 1.2E-7 T 12-10-2018 MIM_c24900 7d2de3e7913eb44af8346633d46027df 382 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 22 378 1.4E-85 T 12-10-2018 IPR010645 Uncharacterised MFS-type transporter YbfB MIM_c24900 7d2de3e7913eb44af8346633d46027df 382 Gene3D G3DSA:1.20.1250.20 211 381 8.8E-9 T 12-10-2018 MIM_c13770 e0af18cfd2ab50f1b128534005487f56 492 Pfam PF03972 MmgE/PrpD family 57 460 1.7E-72 T 12-10-2018 IPR005656 MmgE/PrpD GO:0016829 MIM_c13770 e0af18cfd2ab50f1b128534005487f56 492 Gene3D G3DSA:1.10.4100.10 74 311 4.4E-71 T 12-10-2018 MIM_c13770 e0af18cfd2ab50f1b128534005487f56 492 SUPERFAMILY SSF103378 51 481 4.84E-72 T 12-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 MIM_c13770 e0af18cfd2ab50f1b128534005487f56 492 Gene3D G3DSA:3.30.1330.120 312 410 4.4E-71 T 12-10-2018 MIM_c20090 ddd21b056066983c88541dc633db8841 310 SUPERFAMILY SSF51735 11 261 2.24E-25 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c20090 ddd21b056066983c88541dc633db8841 310 Gene3D G3DSA:3.40.50.720 14 293 6.0E-34 T 12-10-2018 MIM_c20090 ddd21b056066983c88541dc633db8841 310 Gene3D G3DSA:3.90.25.10 163 282 6.0E-34 T 12-10-2018 MIM_c20090 ddd21b056066983c88541dc633db8841 310 Pfam PF05368 NmrA-like family 14 244 1.9E-19 T 12-10-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 MIM_c25270 0551a02f21e0efe0dab5e00f4656732e 221 Gene3D G3DSA:3.10.490.10 33 216 1.7E-15 T 12-10-2018 MIM_c25270 0551a02f21e0efe0dab5e00f4656732e 221 SUPERFAMILY SSF110857 47 159 5.36E-10 T 12-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily MIM_c25270 0551a02f21e0efe0dab5e00f4656732e 221 Pfam PF04752 ChaC-like protein 47 214 8.9E-43 T 12-10-2018 IPR006840 Glutathione-specific gamma-glutamylcyclotransferase GO:0003839|GO:0006751 KEGG: 00480+4.3.2.7|MetaCyc: PWY-7942|Reactome: R-HSA-174403 MIM_c33020 d3545a72bc825342a804736fd4ef9a01 300 SUPERFAMILY SSF46785 4 111 8.84E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c33020 d3545a72bc825342a804736fd4ef9a01 300 Gene3D G3DSA:1.10.10.10 3 89 5.1E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c33020 d3545a72bc825342a804736fd4ef9a01 300 SUPERFAMILY SSF53850 88 296 7.6E-45 T 12-10-2018 MIM_c33020 d3545a72bc825342a804736fd4ef9a01 300 Gene3D G3DSA:3.40.190.10 163 265 1.4E-63 T 12-10-2018 MIM_c33020 d3545a72bc825342a804736fd4ef9a01 300 Pfam PF03466 LysR substrate binding domain 90 293 4.1E-43 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c33020 d3545a72bc825342a804736fd4ef9a01 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.3E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c33020 d3545a72bc825342a804736fd4ef9a01 300 Gene3D G3DSA:3.40.190.10 92 290 1.4E-63 T 12-10-2018 MIM_c38190 b3c132f87654f924e1d7c77e1932d4a9 286 Gene3D G3DSA:3.40.190.10 131 229 3.1E-56 T 12-10-2018 MIM_c38190 b3c132f87654f924e1d7c77e1932d4a9 286 SMART SM00062 46 267 1.6E-53 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c38190 b3c132f87654f924e1d7c77e1932d4a9 286 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 47 265 2.0E-52 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c38190 b3c132f87654f924e1d7c77e1932d4a9 286 SUPERFAMILY SSF53850 17 267 4.6E-58 T 12-10-2018 MIM_c38190 b3c132f87654f924e1d7c77e1932d4a9 286 Gene3D G3DSA:3.40.190.10 44 263 3.1E-56 T 12-10-2018 MIM_c36350 56e1c34f5f2826d4df79ed06d4131073 520 Gene3D G3DSA:3.40.720.10 4 496 9.4E-155 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 MIM_c36350 56e1c34f5f2826d4df79ed06d4131073 520 Pfam PF00884 Sulfatase 5 383 2.0E-54 T 12-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 MIM_c36350 56e1c34f5f2826d4df79ed06d4131073 520 SUPERFAMILY SSF53649 5 492 5.63E-113 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 MIM_c36350 56e1c34f5f2826d4df79ed06d4131073 520 Pfam PF16347 Domain of unknown function (DUF4976) 389 487 1.8E-10 T 12-10-2018 IPR032506 Domain of unknown function DUF4976 Reactome: R-HSA-2024096|Reactome: R-HSA-2206307 MIM_c15060 d574b8c664cec71f3487e160dd7db30f 139 Gene3D G3DSA:1.10.490.10 12 139 8.6E-43 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 MIM_c15060 d574b8c664cec71f3487e160dd7db30f 139 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 65 89 - T 12-10-2018 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 MIM_c15060 d574b8c664cec71f3487e160dd7db30f 139 SUPERFAMILY SSF46458 16 136 9.87E-33 T 12-10-2018 IPR009050 Globin-like superfamily MIM_c15060 d574b8c664cec71f3487e160dd7db30f 139 Pfam PF01152 Bacterial-like globin 16 135 3.3E-38 T 12-10-2018 IPR001486 Truncated hemoglobin GO:0019825 MIM_c27980 96d0bbe2d5f55c7f9e34c523a762aa16 474 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 31 467 3.3E-175 T 12-10-2018 MIM_c27980 96d0bbe2d5f55c7f9e34c523a762aa16 474 Pfam PF04055 Radical SAM superfamily 178 353 1.6E-25 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MIM_c27980 96d0bbe2d5f55c7f9e34c523a762aa16 474 SUPERFAMILY SSF102114 156 399 3.79E-57 T 12-10-2018 MIM_c27980 96d0bbe2d5f55c7f9e34c523a762aa16 474 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 30 468 73.209 T 12-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 MIM_c27980 96d0bbe2d5f55c7f9e34c523a762aa16 474 Gene3D G3DSA:3.80.30.20 172 405 1.6E-79 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe MIM_c27980 96d0bbe2d5f55c7f9e34c523a762aa16 474 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 178 198 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 MIM_c27980 96d0bbe2d5f55c7f9e34c523a762aa16 474 Pfam PF00919 Uncharacterized protein family UPF0004 31 131 4.8E-30 T 12-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 MIM_c27980 96d0bbe2d5f55c7f9e34c523a762aa16 474 SMART SM00729 174 395 8.9E-54 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MIM_c27980 96d0bbe2d5f55c7f9e34c523a762aa16 474 Gene3D G3DSA:3.40.50.12160 30 163 1.7E-34 T 12-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily MIM_c27980 96d0bbe2d5f55c7f9e34c523a762aa16 474 Pfam PF01938 TRAM domain 412 467 1.6E-15 T 12-10-2018 IPR002792 TRAM domain MIM_c27980 96d0bbe2d5f55c7f9e34c523a762aa16 474 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 31 465 1.1E-144 T 12-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 MIM_c20990 f7d5ced038b4ebf2269792a18ef9c3de 486 SUPERFAMILY SSF53720 8 484 9.16E-155 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c20990 f7d5ced038b4ebf2269792a18ef9c3de 486 Pfam PF00171 Aldehyde dehydrogenase family 27 482 1.5E-158 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c20990 f7d5ced038b4ebf2269792a18ef9c3de 486 Gene3D G3DSA:3.40.309.10 260 454 2.4E-166 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MIM_c20990 f7d5ced038b4ebf2269792a18ef9c3de 486 Gene3D G3DSA:3.40.605.10 27 482 2.4E-166 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c20990 f7d5ced038b4ebf2269792a18ef9c3de 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 253 260 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MIM_c29130 0cc214b4e868bdceb44ace248e23933e 329 Pfam PF11876 Protein of unknown function (DUF3396) 89 297 2.9E-61 T 12-10-2018 IPR021815 Protein of unknown function DUF3396 MIM_c20410 e15e6aed89bebc0dbc138fa87a236836 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 320 1.1E-58 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c20410 e15e6aed89bebc0dbc138fa87a236836 325 SUPERFAMILY SSF53850 110 286 1.21E-11 T 12-10-2018 MIM_c20410 e15e6aed89bebc0dbc138fa87a236836 325 PIRSF PIRSF017082 1 323 1.9E-67 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c20410 e15e6aed89bebc0dbc138fa87a236836 325 Gene3D G3DSA:3.40.190.150 30 317 1.5E-87 T 12-10-2018 MIM_c20410 e15e6aed89bebc0dbc138fa87a236836 325 Gene3D G3DSA:3.40.190.10 127 251 1.5E-87 T 12-10-2018 MIM_c17980 90e71cd103a3f15ab0f8a9688b049074 387 PIRSF PIRSF001549 8 331 1.4E-35 T 12-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 MIM_c17980 90e71cd103a3f15ab0f8a9688b049074 387 SUPERFAMILY SSF55681 6 318 4.98E-50 T 12-10-2018 MIM_c17980 90e71cd103a3f15ab0f8a9688b049074 387 Pfam PF13393 Histidyl-tRNA synthetase 12 317 1.1E-106 T 12-10-2018 MIM_c17980 90e71cd103a3f15ab0f8a9688b049074 387 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 18 367 31.653 T 12-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 MIM_c17980 90e71cd103a3f15ab0f8a9688b049074 387 Gene3D G3DSA:3.30.930.10 4 328 8.8E-63 T 12-10-2018 MIM_c25290 947722ec54712484decf509a52ade8f1 214 Pfam PF02630 SCO1/SenC 75 194 1.4E-6 T 12-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c25290 947722ec54712484decf509a52ade8f1 214 Gene3D G3DSA:3.40.30.10 41 209 5.7E-29 T 12-10-2018 MIM_c25290 947722ec54712484decf509a52ade8f1 214 SUPERFAMILY SSF52833 48 206 4.89E-22 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c21340 3593ba99e6b958c0c4b307b84b10a6f0 189 Pfam PF04345 Chorismate lyase 19 181 7.8E-16 T 12-10-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745|MetaCyc: PWY-7929|MetaCyc: PWY-7934|MetaCyc: PWY-7935 MIM_c21340 3593ba99e6b958c0c4b307b84b10a6f0 189 Hamap MF_01632 Chorismate pyruvate-lyase [ubiC]. 8 182 21.391 T 12-10-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745|MetaCyc: PWY-7929|MetaCyc: PWY-7934|MetaCyc: PWY-7935 MIM_c21340 3593ba99e6b958c0c4b307b84b10a6f0 189 SUPERFAMILY SSF64288 8 180 8.38E-38 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MIM_c21340 3593ba99e6b958c0c4b307b84b10a6f0 189 Gene3D G3DSA:3.40.1410.10 4 180 1.8E-31 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MIM_c14190 96fe7e6b9dbb8bdbab5d72855c520706 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 300 2.4E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c14190 96fe7e6b9dbb8bdbab5d72855c520706 307 Gene3D G3DSA:1.10.3720.10 37 294 2.8E-58 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c14190 96fe7e6b9dbb8bdbab5d72855c520706 307 SUPERFAMILY SSF161098 41 306 3.4E-69 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c32390 889db8729d7152bd9ec313318ece4087 282 SUPERFAMILY SSF159501 37 281 3.84E-53 T 12-10-2018 MIM_c32390 889db8729d7152bd9ec313318ece4087 282 PIRSF PIRSF020419 4 282 5.8E-61 T 12-10-2018 IPR016773 Ferric uptake regulator, CjrA, predicted MIM_c32390 889db8729d7152bd9ec313318ece4087 282 Gene3D G3DSA:3.40.50.11550 41 262 1.7E-67 T 12-10-2018 MIM_c32390 889db8729d7152bd9ec313318ece4087 282 Gene3D G3DSA:1.10.8.760 164 218 1.7E-67 T 12-10-2018 MIM_c32390 889db8729d7152bd9ec313318ece4087 282 Pfam PF04187 Haem-binding uptake, Tiki superfamily, ChaN 53 250 6.3E-39 T 12-10-2018 IPR007314 Haem-binding uptake, Tiki superfamily, ChaN MIM_c10500 c3969a75926af97e8208012953d8bf9b 134 Pfam PF13935 Ead/Ea22-like protein 8 106 3.8E-6 T 12-10-2018 IPR025153 Ead/Ea22-like protein MIM_c18210 fdc16ffcb6b6d6ad8c0d4ae89b0cc6f0 301 Pfam PF04381 Putative exonuclease, RdgC 1 296 3.0E-118 T 12-10-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 MIM_c18210 fdc16ffcb6b6d6ad8c0d4ae89b0cc6f0 301 Hamap MF_00194 Recombination-associated protein RdgC [rdgC]. 1 298 36.057 T 12-10-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 MIM_c15360 9ff8a85dbe24713ecae07600c1b6f3e8 275 SUPERFAMILY SSF103481 15 112 9.15E-12 T 12-10-2018 MIM_c15360 9ff8a85dbe24713ecae07600c1b6f3e8 275 SUPERFAMILY SSF103481 159 253 7.32E-14 T 12-10-2018 MIM_c15360 9ff8a85dbe24713ecae07600c1b6f3e8 275 Pfam PF00892 EamA-like transporter family 3 110 2.3E-11 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MIM_c15360 9ff8a85dbe24713ecae07600c1b6f3e8 275 Pfam PF00892 EamA-like transporter family 121 252 3.6E-16 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MIM_c18580 efc81d3307c25a1c163f368ae48eb2be 113 SUPERFAMILY SSF54292 6 109 7.64E-27 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MIM_c18580 efc81d3307c25a1c163f368ae48eb2be 113 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 43 53 - T 12-10-2018 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 MIM_c18580 efc81d3307c25a1c163f368ae48eb2be 113 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 16 92 3.1E-12 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MIM_c18580 efc81d3307c25a1c163f368ae48eb2be 113 Gene3D G3DSA:3.10.20.30 1 113 2.7E-31 T 12-10-2018 IPR012675 Beta-grasp domain superfamily MIM_c18580 efc81d3307c25a1c163f368ae48eb2be 113 PRINTS PR00355 Adrenodoxin signature 43 53 8.2E-10 T 12-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 MIM_c18580 efc81d3307c25a1c163f368ae48eb2be 113 PRINTS PR00355 Adrenodoxin signature 61 75 8.2E-10 T 12-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 MIM_c18580 efc81d3307c25a1c163f368ae48eb2be 113 PRINTS PR00355 Adrenodoxin signature 84 92 8.2E-10 T 12-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 MIM_c18580 efc81d3307c25a1c163f368ae48eb2be 113 TIGRFAM TIGR02007 fdx_isc: ferredoxin, 2Fe-2S type, ISC system 2 112 3.0E-54 T 12-10-2018 IPR011536 Ferredoxin 2Fe-2S type, proteobacteria GO:0009055|GO:0051537 MIM_c20850 beefbac97081c1adc3dba382fbf81e36 502 Gene3D G3DSA:3.40.309.10 279 468 9.1E-191 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MIM_c20850 beefbac97081c1adc3dba382fbf81e36 502 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 274 281 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MIM_c20850 beefbac97081c1adc3dba382fbf81e36 502 Gene3D G3DSA:3.40.605.10 34 496 9.1E-191 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MIM_c20850 beefbac97081c1adc3dba382fbf81e36 502 Pfam PF00171 Aldehyde dehydrogenase family 38 498 1.3E-180 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MIM_c20850 beefbac97081c1adc3dba382fbf81e36 502 SUPERFAMILY SSF53720 31 501 8.51E-174 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c16150 e6e816b2cfe3ff9b0984746f4bde8584 440 Gene3D G3DSA:1.20.1720.10 273 440 1.2E-16 T 12-10-2018 MIM_c16150 e6e816b2cfe3ff9b0984746f4bde8584 440 SUPERFAMILY SSF103473 45 434 7.06E-69 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c16150 e6e816b2cfe3ff9b0984746f4bde8584 440 Gene3D G3DSA:1.20.1250.20 41 272 3.0E-44 T 12-10-2018 MIM_c16150 e6e816b2cfe3ff9b0984746f4bde8584 440 Pfam PF07690 Major Facilitator Superfamily 52 280 5.4E-30 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c16150 e6e816b2cfe3ff9b0984746f4bde8584 440 PRINTS PR01035 Tetracycline resistance protein signature 119 143 3.5E-12 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MIM_c16150 e6e816b2cfe3ff9b0984746f4bde8584 440 PRINTS PR01035 Tetracycline resistance protein signature 146 167 3.5E-12 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MIM_c16150 e6e816b2cfe3ff9b0984746f4bde8584 440 PRINTS PR01035 Tetracycline resistance protein signature 57 73 3.5E-12 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MIM_c16150 e6e816b2cfe3ff9b0984746f4bde8584 440 PRINTS PR01035 Tetracycline resistance protein signature 176 198 3.5E-12 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MIM_c16150 e6e816b2cfe3ff9b0984746f4bde8584 440 PRINTS PR01035 Tetracycline resistance protein signature 381 404 3.5E-12 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MIM_c05930 11565b4f7345760e207290b0ae3357ae 369 SUPERFAMILY SSF56266 19 361 6.02E-95 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MIM_c05930 11565b4f7345760e207290b0ae3357ae 369 Pfam PF03576 Peptidase family S58 25 359 1.5E-108 T 12-10-2018 IPR005321 Peptidase S58, DmpA MIM_c05930 11565b4f7345760e207290b0ae3357ae 369 Gene3D G3DSA:3.60.70.12 11 368 1.6E-122 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MIM_c01190 2715ea57ee0165e3f4c306dfa49045d8 554 Pfam PF01266 FAD dependent oxidoreductase 28 390 1.4E-55 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MIM_c01190 2715ea57ee0165e3f4c306dfa49045d8 554 Gene3D G3DSA:1.10.8.870 431 538 2.4E-18 T 12-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MIM_c01190 2715ea57ee0165e3f4c306dfa49045d8 554 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 383 393 - T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MIM_c01190 2715ea57ee0165e3f4c306dfa49045d8 554 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 414 513 2.1E-16 T 12-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MIM_c01190 2715ea57ee0165e3f4c306dfa49045d8 554 SUPERFAMILY SSF51905 26 355 3.56E-41 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c01190 2715ea57ee0165e3f4c306dfa49045d8 554 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 56 68 7.8E-30 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MIM_c01190 2715ea57ee0165e3f4c306dfa49045d8 554 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 378 390 7.8E-30 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MIM_c01190 2715ea57ee0165e3f4c306dfa49045d8 554 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 345 351 7.8E-30 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MIM_c01190 2715ea57ee0165e3f4c306dfa49045d8 554 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 40 50 7.8E-30 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MIM_c01190 2715ea57ee0165e3f4c306dfa49045d8 554 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 101 113 7.8E-30 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MIM_c01190 2715ea57ee0165e3f4c306dfa49045d8 554 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 27 39 7.8E-30 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MIM_c01190 2715ea57ee0165e3f4c306dfa49045d8 554 Gene3D G3DSA:3.50.50.60 28 397 1.9E-128 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c01190 2715ea57ee0165e3f4c306dfa49045d8 554 Gene3D G3DSA:3.30.9.10 105 352 1.9E-128 T 12-10-2018 MIM_c24260 65864e867836059691d70fa2cbeec17c 88 Pfam PF01722 BolA-like protein 16 85 2.0E-22 T 12-10-2018 IPR002634 BolA protein MIM_c24260 65864e867836059691d70fa2cbeec17c 88 PIRSF PIRSF003113 1 87 2.6E-20 T 12-10-2018 IPR002634 BolA protein MIM_c24260 65864e867836059691d70fa2cbeec17c 88 Gene3D G3DSA:3.30.300.90 4 88 1.2E-21 T 12-10-2018 MIM_c24260 65864e867836059691d70fa2cbeec17c 88 SUPERFAMILY SSF82657 7 85 9.02E-19 T 12-10-2018 IPR036065 BolA-like superfamily MIM_c01330 cdec64ccf81f83b0b96617b170b78389 391 Gene3D G3DSA:3.40.50.10800 225 320 4.3E-91 T 12-10-2018 MIM_c01330 cdec64ccf81f83b0b96617b170b78389 391 Gene3D G3DSA:3.40.50.10800 140 363 4.3E-91 T 12-10-2018 MIM_c01330 cdec64ccf81f83b0b96617b170b78389 391 Gene3D G3DSA:3.40.50.10800 58 345 4.3E-91 T 12-10-2018 MIM_c01330 cdec64ccf81f83b0b96617b170b78389 391 Pfam PF02445 Quinolinate synthetase A protein 58 363 5.1E-100 T 12-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 MIM_c01330 cdec64ccf81f83b0b96617b170b78389 391 SUPERFAMILY SSF142754 57 364 9.68E-104 T 12-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 MIM_c01330 cdec64ccf81f83b0b96617b170b78389 391 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 52 364 2.0E-105 T 12-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 MIM_c13470 23c078f3a5a3fa1bae5b01f6a25ce71e 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 318 2.6E-86 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c13470 23c078f3a5a3fa1bae5b01f6a25ce71e 322 SUPERFAMILY SSF53850 108 283 2.26E-14 T 12-10-2018 MIM_c13470 23c078f3a5a3fa1bae5b01f6a25ce71e 322 PIRSF PIRSF017082 1 322 1.6E-78 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c13470 23c078f3a5a3fa1bae5b01f6a25ce71e 322 Gene3D G3DSA:3.40.190.150 29 312 5.8E-110 T 12-10-2018 MIM_c13470 23c078f3a5a3fa1bae5b01f6a25ce71e 322 Gene3D G3DSA:3.40.190.10 124 247 5.8E-110 T 12-10-2018 MIM_c04660 14daba3f099c516269bd532f3630d3aa 289 SMART SM00382 49 239 3.1E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c04660 14daba3f099c516269bd532f3630d3aa 289 SUPERFAMILY SSF52540 19 236 1.64E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c04660 14daba3f099c516269bd532f3630d3aa 289 Gene3D G3DSA:3.40.50.300 17 258 1.1E-61 T 12-10-2018 MIM_c04660 14daba3f099c516269bd532f3630d3aa 289 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c04660 14daba3f099c516269bd532f3630d3aa 289 Pfam PF00005 ABC transporter 40 179 1.9E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c22050 0c2f307bc41b6d93b9d593c4cb91677c 425 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 39 411 1.3E-172 T 12-10-2018 IPR017777 Urea ABC transporter, substrate-binding protein UrtA-like MIM_c22050 0c2f307bc41b6d93b9d593c4cb91677c 425 Gene3D G3DSA:3.40.50.2300 154 401 2.3E-131 T 12-10-2018 MIM_c22050 0c2f307bc41b6d93b9d593c4cb91677c 425 Pfam PF13433 Periplasmic binding protein domain 39 413 5.4E-166 T 12-10-2018 MIM_c22050 0c2f307bc41b6d93b9d593c4cb91677c 425 SUPERFAMILY SSF53822 38 415 1.27E-84 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c22050 0c2f307bc41b6d93b9d593c4cb91677c 425 Gene3D G3DSA:3.40.50.2300 41 382 2.3E-131 T 12-10-2018 MIM_c29480 8be014d2073d4790505f8a59c55a59d4 634 Pfam PF00773 RNB domain 469 512 3.2E-10 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 MIM_c29480 8be014d2073d4790505f8a59c55a59d4 634 SUPERFAMILY SSF50249 235 565 5.08E-69 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c29480 8be014d2073d4790505f8a59c55a59d4 634 Pfam PF00773 RNB domain 239 469 1.2E-32 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 MIM_c29480 8be014d2073d4790505f8a59c55a59d4 634 SMART SM00955 234 515 5.4E-51 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 MIM_c29480 8be014d2073d4790505f8a59c55a59d4 634 ProSitePatterns PS01175 Ribonuclease II family signature. 482 506 - T 12-10-2018 IPR022966 Ribonuclease II/R, conserved site MIM_c39930 4a05b866f60ff58427436f49b41e4f94 315 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 1 310 2.7E-90 T 12-10-2018 IPR007296 Domain of unknown function DUF403 MIM_c36940 7e48f8a2495a99a6515464b392fe0cd5 272 Gene3D G3DSA:1.10.260.40 9 105 1.3E-6 T 12-10-2018 MIM_c36940 7e48f8a2495a99a6515464b392fe0cd5 272 SUPERFAMILY SSF47413 35 87 2.81E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c36940 7e48f8a2495a99a6515464b392fe0cd5 272 Gene3D G3DSA:3.30.450.180 110 270 8.4E-16 T 12-10-2018 MIM_c36940 7e48f8a2495a99a6515464b392fe0cd5 272 Pfam PF13560 Helix-turn-helix domain 12 91 2.9E-17 T 12-10-2018 MIM_c36940 7e48f8a2495a99a6515464b392fe0cd5 272 SMART SM00530 16 88 1.6E-4 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c03970 9c7acc5c6cef79150ed92a41bf787266 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 285 2.3E-25 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c03970 9c7acc5c6cef79150ed92a41bf787266 295 Gene3D G3DSA:1.10.3720.10 94 286 1.1E-23 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c03970 9c7acc5c6cef79150ed92a41bf787266 295 SUPERFAMILY SSF161098 92 273 7.98E-33 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c31380 e53001305a59ac572f43bbbb0aa49c6b 399 SUPERFAMILY SSF89796 8 392 2.22E-134 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c31380 e53001305a59ac572f43bbbb0aa49c6b 399 Pfam PF02515 CoA-transferase family III 9 384 3.0E-128 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 MIM_c31380 e53001305a59ac572f43bbbb0aa49c6b 399 Gene3D G3DSA:3.40.50.10540 9 347 7.7E-136 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c31380 e53001305a59ac572f43bbbb0aa49c6b 399 Gene3D G3DSA:3.30.1540.10 237 328 7.7E-136 T 12-10-2018 MIM_c03980 f8b13195e939851a3ed7ef1c2c68a7d5 236 Pfam PF00005 ABC transporter 23 150 2.3E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c03980 f8b13195e939851a3ed7ef1c2c68a7d5 236 SUPERFAMILY SSF52540 8 204 1.97E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c03980 f8b13195e939851a3ed7ef1c2c68a7d5 236 SMART SM00382 32 200 7.8E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c03980 f8b13195e939851a3ed7ef1c2c68a7d5 236 Gene3D G3DSA:3.40.50.300 2 212 2.8E-57 T 12-10-2018 MIM_c03980 f8b13195e939851a3ed7ef1c2c68a7d5 236 ProSitePatterns PS00211 ABC transporters family signature. 123 137 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c37540 9b29a23206b9311c98ff0c3ff4b453da 340 Pfam PF04199 Putative cyclase 78 268 6.4E-16 T 12-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 MIM_c37540 9b29a23206b9311c98ff0c3ff4b453da 340 SUPERFAMILY SSF102198 96 339 1.57E-13 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 MIM_c37540 9b29a23206b9311c98ff0c3ff4b453da 340 Gene3D G3DSA:3.50.30.50 72 340 7.0E-12 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 MIM_c12210 67fe646e1c1ac7bf5596ac6d21cad202 135 Pfam PF03928 Haem-degrading 7 130 4.3E-30 T 12-10-2018 IPR005624 Haem-degrading MIM_c12210 67fe646e1c1ac7bf5596ac6d21cad202 135 Gene3D G3DSA:3.30.450.150 1 134 3.3E-37 T 12-10-2018 IPR038084 GlcG-like domain superfamily MIM_c12210 67fe646e1c1ac7bf5596ac6d21cad202 135 SUPERFAMILY SSF143744 2 133 4.84E-36 T 12-10-2018 IPR038084 GlcG-like domain superfamily MIM_c14470 83b20bfa8f42d30b7a9eb47c8ff7e6c7 99 Gene3D G3DSA:1.20.1290.10 7 99 2.4E-26 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c14470 83b20bfa8f42d30b7a9eb47c8ff7e6c7 99 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 35 85 5.4E-18 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c14470 83b20bfa8f42d30b7a9eb47c8ff7e6c7 99 SUPERFAMILY SSF69118 16 98 1.57E-25 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c14470 83b20bfa8f42d30b7a9eb47c8ff7e6c7 99 Pfam PF02627 Carboxymuconolactone decarboxylase family 18 96 9.3E-21 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c40910 fb3c946e0a046028b127f45a06509724 272 SUPERFAMILY SSF161098 64 249 3.14E-24 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c40910 fb3c946e0a046028b127f45a06509724 272 Gene3D G3DSA:1.10.3720.10 59 266 1.2E-20 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c40910 fb3c946e0a046028b127f45a06509724 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 267 1.8E-24 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c14910 1b7cc6e03a07826f278c3f601300d122 147 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 14 142 7.9E-31 T 12-10-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein MIM_c14910 1b7cc6e03a07826f278c3f601300d122 147 SUPERFAMILY SSF64076 5 143 1.31E-28 T 12-10-2018 IPR036748 MTH938-like superfamily MIM_c14910 1b7cc6e03a07826f278c3f601300d122 147 Gene3D G3DSA:3.40.1230.10 2 145 2.7E-37 T 12-10-2018 IPR036748 MTH938-like superfamily MIM_c02960 2108b0a9dcdf5ad2b84397132c18e870 463 PIRSF PIRSF000204 1 463 3.8E-230 T 12-10-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 MIM_c02960 2108b0a9dcdf5ad2b84397132c18e870 463 Gene3D G3DSA:3.40.50.1220 286 463 9.6E-87 T 12-10-2018 MIM_c02960 2108b0a9dcdf5ad2b84397132c18e870 463 Pfam PF02233 NAD(P) transhydrogenase beta subunit 7 460 1.7E-202 T 12-10-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 MIM_c02960 2108b0a9dcdf5ad2b84397132c18e870 463 SUPERFAMILY SSF52467 289 463 3.47E-76 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MIM_c02090 8e4e0abfc4756e50b119530fd55cdb60 91 Gene3D G3DSA:1.20.58.1000 1 91 1.9E-26 T 12-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily MIM_c02090 8e4e0abfc4756e50b119530fd55cdb60 91 Pfam PF02583 Metal-sensitive transcriptional repressor 8 87 2.2E-18 T 12-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 MIM_c38800 b659547732366086224e399083a0d438 278 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 265 1.9E-109 T 12-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 MIM_c38800 b659547732366086224e399083a0d438 278 SUPERFAMILY SSF53448 2 269 1.06E-64 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MIM_c38800 b659547732366086224e399083a0d438 278 Gene3D G3DSA:3.90.550.10 1 277 3.5E-86 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MIM_c38800 b659547732366086224e399083a0d438 278 Pfam PF00483 Nucleotidyl transferase 11 268 5.5E-29 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MIM_c12270 1aa3a5b016683851bee2357635ff3739 209 SUPERFAMILY SSF55821 1 202 2.29E-58 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily MIM_c12270 1aa3a5b016683851bee2357635ff3739 209 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 201 6.7E-54 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 MIM_c12270 1aa3a5b016683851bee2357635ff3739 209 Pfam PF01300 Telomere recombination 23 198 1.7E-40 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 MIM_c12270 1aa3a5b016683851bee2357635ff3739 209 Gene3D G3DSA:3.90.870.10 2 205 3.8E-57 T 12-10-2018 MIM_c00920 26de305921c08b63088329824e717686 409 Pfam PF07690 Major Facilitator Superfamily 32 296 1.8E-34 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c00920 26de305921c08b63088329824e717686 409 Gene3D G3DSA:1.20.1250.20 24 219 2.4E-29 T 12-10-2018 MIM_c00920 26de305921c08b63088329824e717686 409 SUPERFAMILY SSF103473 1 400 1.44E-57 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c00920 26de305921c08b63088329824e717686 409 Gene3D G3DSA:1.20.1250.20 220 403 2.7E-13 T 12-10-2018 MIM_c04670 28c8132326489652e5547463c8dbee16 295 Gene3D G3DSA:1.10.3720.10 96 289 1.3E-25 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c04670 28c8132326489652e5547463c8dbee16 295 SUPERFAMILY SSF161098 96 282 2.62E-34 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c04670 28c8132326489652e5547463c8dbee16 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 289 9.8E-25 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c16930 9c580e24b31dd1815876162414d2b377 386 SUPERFAMILY SSF54826 3 113 9.19E-10 T 12-10-2018 MIM_c16930 9c580e24b31dd1815876162414d2b377 386 Gene3D G3DSA:3.20.20.120 104 356 4.9E-77 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MIM_c16930 9c580e24b31dd1815876162414d2b377 386 SUPERFAMILY SSF51604 101 374 6.39E-51 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MIM_c16930 9c580e24b31dd1815876162414d2b377 386 Gene3D G3DSA:3.30.390.10 12 374 4.9E-77 T 12-10-2018 IPR029017 Enolase-like, N-terminal MIM_c16930 9c580e24b31dd1815876162414d2b377 386 Pfam PF13378 Enolase C-terminal domain-like 136 366 1.1E-42 T 12-10-2018 IPR029065 Enolase C-terminal domain-like MIM_c16930 9c580e24b31dd1815876162414d2b377 386 SMART SM00922 131 243 1.0E-12 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MIM_c40480 e504a3af1b0a9929de220dc700b3d1e1 188 SUPERFAMILY SSF54637 5 126 9.54E-20 T 12-10-2018 IPR029069 HotDog domain superfamily MIM_c40480 e504a3af1b0a9929de220dc700b3d1e1 188 Gene3D G3DSA:3.10.129.10 2 141 2.7E-14 T 12-10-2018 MIM_c40480 e504a3af1b0a9929de220dc700b3d1e1 188 PIRSF PIRSF020565 1 188 3.6E-41 T 12-10-2018 IPR016776 3-hydroxylacyl-(acyl carrier protein) dehydratase, predicted MIM_c08550 bb811b70ecd8b7ca8bbdc49b797ec84a 241 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 MIM_c08550 bb811b70ecd8b7ca8bbdc49b797ec84a 241 Gene3D G3DSA:3.90.226.10 2 240 3.4E-71 T 12-10-2018 MIM_c08550 bb811b70ecd8b7ca8bbdc49b797ec84a 241 SUPERFAMILY SSF52096 2 235 7.76E-73 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c08550 bb811b70ecd8b7ca8bbdc49b797ec84a 241 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 228 3.8E-56 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c33690 52d2a027e72de48b2febd01a2d6291cb 356 Gene3D G3DSA:3.20.20.100 15 353 4.5E-96 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MIM_c33690 52d2a027e72de48b2febd01a2d6291cb 356 Pfam PF00248 Aldo/keto reductase family 30 331 2.3E-64 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain MIM_c33690 52d2a027e72de48b2febd01a2d6291cb 356 SUPERFAMILY SSF51430 16 339 1.03E-84 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MIM_c36680 e4cf9950052a51a9a12ce140904d69e3 130 Pfam PF12680 SnoaL-like domain 11 113 6.9E-24 T 12-10-2018 IPR037401 SnoaL-like domain MIM_c36680 e4cf9950052a51a9a12ce140904d69e3 130 Gene3D G3DSA:3.10.450.50 1 122 1.2E-30 T 12-10-2018 MIM_c36680 e4cf9950052a51a9a12ce140904d69e3 130 SUPERFAMILY SSF54427 4 115 1.52E-29 T 12-10-2018 IPR032710 NTF2-like domain superfamily MIM_c33700 ebb13df91d8ec937dba8de66191f1ede 169 SUPERFAMILY SSF50475 9 162 7.36E-46 T 12-10-2018 MIM_c33700 ebb13df91d8ec937dba8de66191f1ede 169 Gene3D G3DSA:2.30.110.10 6 168 2.9E-52 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MIM_c33700 ebb13df91d8ec937dba8de66191f1ede 169 Pfam PF01613 Flavin reductase like domain 18 163 2.3E-36 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MIM_c33700 ebb13df91d8ec937dba8de66191f1ede 169 SMART SM00903 17 162 2.5E-56 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MIM_c07630 115ce2eb94ce0806c895ec6b1f173f71 407 SUPERFAMILY SSF89796 6 406 3.01E-143 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c07630 115ce2eb94ce0806c895ec6b1f173f71 407 Gene3D G3DSA:3.30.1540.10 246 337 1.3E-146 T 12-10-2018 MIM_c07630 115ce2eb94ce0806c895ec6b1f173f71 407 Gene3D G3DSA:3.40.50.10540 7 404 1.3E-146 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c07630 115ce2eb94ce0806c895ec6b1f173f71 407 Pfam PF02515 CoA-transferase family III 8 386 1.5E-131 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 MIM_c11960 5c8f40492a1c0086514e6a83b1df2933 199 Pfam PF00881 Nitroreductase family 10 177 1.5E-15 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MIM_c11960 5c8f40492a1c0086514e6a83b1df2933 199 Gene3D G3DSA:3.40.109.10 2 199 2.4E-84 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MIM_c11960 5c8f40492a1c0086514e6a83b1df2933 199 SUPERFAMILY SSF55469 4 198 4.06E-71 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MIM_c05910 7b1b6dbbb17368216e64b00682a89a11 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 304 1.6E-44 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c05910 7b1b6dbbb17368216e64b00682a89a11 306 Gene3D G3DSA:1.10.3720.10 87 299 4.4E-26 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c05910 7b1b6dbbb17368216e64b00682a89a11 306 SUPERFAMILY SSF161098 94 289 2.75E-21 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c31860 f64de4dbef419ce2f72ea3afb36cf227 287 SMART SM00530 23 78 1.2E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c31860 f64de4dbef419ce2f72ea3afb36cf227 287 SUPERFAMILY SSF47413 17 76 2.04E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c31860 f64de4dbef419ce2f72ea3afb36cf227 287 Gene3D G3DSA:1.10.260.40 2 79 3.4E-11 T 12-10-2018 MIM_c31860 f64de4dbef419ce2f72ea3afb36cf227 287 Pfam PF01381 Helix-turn-helix 24 77 2.6E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c31860 f64de4dbef419ce2f72ea3afb36cf227 287 Gene3D G3DSA:3.30.450.180 103 286 1.1E-5 T 12-10-2018 MIM_c02510 042c8b0d98a915e442471ef02e198b68 308 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 47 287 3.5E-34 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region MIM_c02510 042c8b0d98a915e442471ef02e198b68 308 SUPERFAMILY SSF63829 27 295 9.48E-53 T 12-10-2018 MIM_c02510 042c8b0d98a915e442471ef02e198b68 308 Gene3D G3DSA:2.120.10.30 37 305 7.8E-60 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MIM_c26400 419a5e5eca5557475be94d961e4e9ecd 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 303 4.1E-29 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c26400 419a5e5eca5557475be94d961e4e9ecd 306 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 21 73 1.3E-12 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MIM_c26400 419a5e5eca5557475be94d961e4e9ecd 306 SUPERFAMILY SSF161098 97 284 7.46E-28 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c26400 419a5e5eca5557475be94d961e4e9ecd 306 Gene3D G3DSA:1.10.3720.10 90 302 1.3E-22 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c30810 285ecfd806fd92bf9a1b88cf7ab5b883 319 SUPERFAMILY SSF53807 29 298 8.63E-62 T 12-10-2018 MIM_c30810 285ecfd806fd92bf9a1b88cf7ab5b883 319 Gene3D G3DSA:3.40.50.1980 138 314 4.4E-51 T 12-10-2018 MIM_c30810 285ecfd806fd92bf9a1b88cf7ab5b883 319 Gene3D G3DSA:3.40.50.1980 29 137 3.1E-32 T 12-10-2018 MIM_c30810 285ecfd806fd92bf9a1b88cf7ab5b883 319 Pfam PF01497 Periplasmic binding protein 51 288 2.4E-28 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain MIM_c31300 85f29a386657ef35c4bc27149bd756f0 299 Gene3D G3DSA:3.20.20.150 12 289 1.4E-82 T 12-10-2018 MIM_c31300 85f29a386657ef35c4bc27149bd756f0 299 Pfam PF05114 Protein of unknown function (DUF692) 16 280 3.2E-100 T 12-10-2018 IPR007801 Uncharacterised protein family UPF0276 MIM_c31300 85f29a386657ef35c4bc27149bd756f0 299 SUPERFAMILY SSF51658 37 282 3.31E-10 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily MIM_c37350 d93e92ca7980aa86d25cf9d0f03e6e9d 315 SUPERFAMILY SSF53850 101 312 2.02E-40 T 12-10-2018 MIM_c37350 d93e92ca7980aa86d25cf9d0f03e6e9d 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 27 74 9.0E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c37350 d93e92ca7980aa86d25cf9d0f03e6e9d 315 Gene3D G3DSA:3.40.190.10 174 278 3.5E-58 T 12-10-2018 MIM_c37350 d93e92ca7980aa86d25cf9d0f03e6e9d 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 51 5.6E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c37350 d93e92ca7980aa86d25cf9d0f03e6e9d 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 51 62 5.6E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c37350 d93e92ca7980aa86d25cf9d0f03e6e9d 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 41 5.6E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c37350 d93e92ca7980aa86d25cf9d0f03e6e9d 315 Gene3D G3DSA:1.10.10.10 20 102 1.2E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c37350 d93e92ca7980aa86d25cf9d0f03e6e9d 315 Gene3D G3DSA:3.40.190.10 103 306 3.5E-58 T 12-10-2018 MIM_c37350 d93e92ca7980aa86d25cf9d0f03e6e9d 315 Pfam PF03466 LysR substrate binding domain 99 309 2.0E-37 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c37350 d93e92ca7980aa86d25cf9d0f03e6e9d 315 SUPERFAMILY SSF46785 16 122 1.7E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c38470 ef4d1cf084147b9811df1cf69c40ff06 224 Pfam PF02669 K+-transporting ATPase, c chain 21 214 1.4E-68 T 12-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 MIM_c38470 ef4d1cf084147b9811df1cf69c40ff06 224 PIRSF PIRSF001296 16 220 4.9E-72 T 12-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 MIM_c38470 ef4d1cf084147b9811df1cf69c40ff06 224 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 17 216 32.494 T 12-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 MIM_c38470 ef4d1cf084147b9811df1cf69c40ff06 224 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 20 215 2.5E-61 T 12-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 MIM_c12520 893a3d6c45bf6ead2d3afc61dce5d5a1 390 SUPERFAMILY SSF53901 10 231 1.79E-26 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c12520 893a3d6c45bf6ead2d3afc61dce5d5a1 390 Gene3D G3DSA:3.40.47.10 4 386 5.0E-115 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c12520 893a3d6c45bf6ead2d3afc61dce5d5a1 390 PIRSF PIRSF000429 5 382 5.0E-30 T 12-10-2018 IPR002155 Thiolase GO:0016747 MIM_c12520 893a3d6c45bf6ead2d3afc61dce5d5a1 390 SUPERFAMILY SSF53901 240 376 5.59E-27 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c12520 893a3d6c45bf6ead2d3afc61dce5d5a1 390 Pfam PF02803 Thiolase, C-terminal domain 267 371 1.4E-6 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 MIM_c03300 e9f8c9893d76353ace4c2de1515ffde8 621 ProDom PD043552 KINASE KINASE/PHOSPHATASE ISOCITRATE DEHYDROGENASE 3.1.3.- IDH TRANSFERASE IDHK/P HYDROLASE ENZYME 20 603 0.0 T 12-10-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 MIM_c03300 e9f8c9893d76353ace4c2de1515ffde8 621 PIRSF PIRSF000719 18 608 9.7E-208 T 12-10-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 MIM_c03300 e9f8c9893d76353ace4c2de1515ffde8 621 Hamap MF_00747 Isocitrate dehydrogenase kinase/phosphatase [aceK]. 15 606 41.623 T 12-10-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 MIM_c03300 e9f8c9893d76353ace4c2de1515ffde8 621 Pfam PF06315 Isocitrate dehydrogenase kinase/phosphatase (AceK) 23 602 3.2E-245 T 12-10-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 MIM_c11240 c10e4d371bafdd7c7555f9c94811b0d6 375 Pfam PF00149 Calcineurin-like phosphoesterase 148 314 5.7E-11 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MIM_c11240 c10e4d371bafdd7c7555f9c94811b0d6 375 Gene3D G3DSA:3.60.21.10 147 333 2.4E-22 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like MIM_c11240 c10e4d371bafdd7c7555f9c94811b0d6 375 SUPERFAMILY SSF56300 144 373 9.3E-34 T 12-10-2018 MIM_c17130 c51b17174db72cc04ace8d0bb8beedd0 302 Gene3D G3DSA:1.10.10.10 3 91 6.4E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c17130 c51b17174db72cc04ace8d0bb8beedd0 302 Gene3D G3DSA:3.40.190.10 163 263 5.5E-59 T 12-10-2018 MIM_c17130 c51b17174db72cc04ace8d0bb8beedd0 302 SUPERFAMILY SSF46785 3 109 2.14E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c17130 c51b17174db72cc04ace8d0bb8beedd0 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.0E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c17130 c51b17174db72cc04ace8d0bb8beedd0 302 SUPERFAMILY SSF53850 89 294 2.53E-42 T 12-10-2018 MIM_c17130 c51b17174db72cc04ace8d0bb8beedd0 302 Pfam PF03466 LysR substrate binding domain 88 288 1.1E-39 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c17130 c51b17174db72cc04ace8d0bb8beedd0 302 Gene3D G3DSA:3.40.190.10 92 288 5.5E-59 T 12-10-2018 MIM_c17130 c51b17174db72cc04ace8d0bb8beedd0 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 6.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c17130 c51b17174db72cc04ace8d0bb8beedd0 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 6.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c17130 c51b17174db72cc04ace8d0bb8beedd0 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 6.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c09520 051143fa99204c0c92028bf6d33653e9 348 Gene3D G3DSA:3.40.50.2300 64 307 7.0E-67 T 12-10-2018 MIM_c09520 051143fa99204c0c92028bf6d33653e9 348 Pfam PF13377 Periplasmic binding protein-like domain 169 330 2.4E-29 T 12-10-2018 MIM_c09520 051143fa99204c0c92028bf6d33653e9 348 Gene3D G3DSA:1.10.260.40 1 61 2.1E-21 T 12-10-2018 MIM_c09520 051143fa99204c0c92028bf6d33653e9 348 Gene3D G3DSA:3.40.50.2300 161 291 7.0E-67 T 12-10-2018 MIM_c09520 051143fa99204c0c92028bf6d33653e9 348 SUPERFAMILY SSF53822 64 335 1.34E-66 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c09520 051143fa99204c0c92028bf6d33653e9 348 SMART SM00354 4 74 9.7E-27 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MIM_c09520 051143fa99204c0c92028bf6d33653e9 348 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 48 1.2E-17 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MIM_c09520 051143fa99204c0c92028bf6d33653e9 348 SUPERFAMILY SSF47413 4 61 3.21E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c36870 223235b72255a292830b265e674a5b2c 453 Pfam PF13449 Esterase-like activity of phytase 91 425 2.0E-62 T 12-10-2018 IPR027372 Phytase-like domain MIM_c21060 9f316960ef534a2c6855cb08d0fd65b2 141 SUPERFAMILY SSF82784 1 140 3.14E-45 T 12-10-2018 IPR036102 OsmC/Ohr superfamily MIM_c21060 9f316960ef534a2c6855cb08d0fd65b2 141 Gene3D G3DSA:2.20.25.10 1 47 6.3E-23 T 12-10-2018 MIM_c21060 9f316960ef534a2c6855cb08d0fd65b2 141 Pfam PF02566 OsmC-like protein 42 138 4.6E-18 T 12-10-2018 IPR003718 OsmC/Ohr family MIM_c21060 9f316960ef534a2c6855cb08d0fd65b2 141 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 7 140 3.4E-56 T 12-10-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 MIM_c21060 9f316960ef534a2c6855cb08d0fd65b2 141 Gene3D G3DSA:3.30.300.20 48 141 8.4E-34 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta MIM_c00560 3b4139bc277a86d717bbdceb4c9709bc 431 Pfam PF13416 Bacterial extracellular solute-binding protein 58 370 1.5E-33 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein MIM_c00560 3b4139bc277a86d717bbdceb4c9709bc 431 SUPERFAMILY SSF53850 35 428 2.03E-62 T 12-10-2018 MIM_c00560 3b4139bc277a86d717bbdceb4c9709bc 431 Gene3D G3DSA:3.40.190.10 32 430 7.9E-66 T 12-10-2018 MIM_c06860 04e3aa301a85835073dd0e1b98cec492 306 Pfam PF01370 NAD dependent epimerase/dehydratase family 9 230 7.8E-44 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MIM_c06860 04e3aa301a85835073dd0e1b98cec492 306 Gene3D G3DSA:3.40.50.720 9 281 1.9E-79 T 12-10-2018 MIM_c06860 04e3aa301a85835073dd0e1b98cec492 306 Gene3D G3DSA:3.90.25.10 174 269 1.9E-79 T 12-10-2018 MIM_c06860 04e3aa301a85835073dd0e1b98cec492 306 SUPERFAMILY SSF51735 3 297 2.86E-62 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c32980 4a3bbca0113727790757e56b78c76c5c 2128 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 1780 2124 4.9E-36 T 12-10-2018 IPR007452 Translocation and assembly module TamB MIM_c28590 cb6b5f399d3aa64648d71c530f8fb342 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 224 2.9E-16 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MIM_c28590 cb6b5f399d3aa64648d71c530f8fb342 231 Gene3D G3DSA:1.10.10.10 129 230 1.4E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c28590 cb6b5f399d3aa64648d71c530f8fb342 231 SMART SM00448 5 117 6.3E-36 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c28590 cb6b5f399d3aa64648d71c530f8fb342 231 Gene3D G3DSA:3.40.50.2300 1 127 2.2E-34 T 12-10-2018 MIM_c28590 cb6b5f399d3aa64648d71c530f8fb342 231 SMART SM00862 151 224 9.2E-17 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MIM_c28590 cb6b5f399d3aa64648d71c530f8fb342 231 Pfam PF00072 Response regulator receiver domain 7 118 7.3E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c28590 cb6b5f399d3aa64648d71c530f8fb342 231 SUPERFAMILY SSF52172 4 185 7.54E-37 T 12-10-2018 IPR011006 CheY-like superfamily MIM_c00950 fec33f45d655f0a6076e08b810d1bf3b 135 Pfam PF01638 HxlR-like helix-turn-helix 23 110 9.0E-35 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type MIM_c00950 fec33f45d655f0a6076e08b810d1bf3b 135 SUPERFAMILY SSF46785 13 111 8.65E-34 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c00950 fec33f45d655f0a6076e08b810d1bf3b 135 Gene3D G3DSA:1.10.10.10 3 116 5.1E-39 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c29740 e569ebccd683dd56864270e335ce6c85 186 SUPERFAMILY SSF57561 65 185 2.22E-60 T 12-10-2018 IPR036560 Methylamine/Aralkylamine dehydrogenase light chain superfamily GO:0009308|GO:0016638|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 MIM_c29740 e569ebccd683dd56864270e335ce6c85 186 Gene3D G3DSA:2.60.30.10 51 186 1.3E-64 T 12-10-2018 IPR036560 Methylamine/Aralkylamine dehydrogenase light chain superfamily GO:0009308|GO:0016638|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 MIM_c29740 e569ebccd683dd56864270e335ce6c85 186 TIGRFAM TIGR02659 TTQ_MADH_Lt: methylamine dehydrogenase (amicyanin) light chain 1 186 5.6E-107 T 12-10-2018 IPR004229 Methylamine dehydrogenase light chain GO:0030288|GO:0052876|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 MIM_c29740 e569ebccd683dd56864270e335ce6c85 186 PIRSF PIRSF000192 1 186 3.5E-109 T 12-10-2018 IPR016008 Amine dehydrogenase light chain GO:0009308|GO:0030058|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 MIM_c29740 e569ebccd683dd56864270e335ce6c85 186 Pfam PF02975 Methylamine dehydrogenase, L chain 72 184 2.4E-51 T 12-10-2018 IPR013504 Methylamine/Aralkylamine dehydrogenase light chain, C-terminal domain GO:0009308|GO:0016638|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 MIM_c28750 2616a15aa44c2184a8d1c6e9d1f65d7f 919 Pfam PF13599 Pentapeptide repeats (9 copies) 704 781 5.0E-10 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c28750 2616a15aa44c2184a8d1c6e9d1f65d7f 919 SUPERFAMILY SSF141571 588 696 3.14E-25 T 12-10-2018 MIM_c28750 2616a15aa44c2184a8d1c6e9d1f65d7f 919 Gene3D G3DSA:2.160.20.80 533 700 1.4E-24 T 12-10-2018 MIM_c28750 2616a15aa44c2184a8d1c6e9d1f65d7f 919 Pfam PF09937 Uncharacterized protein conserved in bacteria (DUF2169) 20 304 4.6E-80 T 12-10-2018 IPR018683 Domain of unknown function DUF2169 MIM_c28750 2616a15aa44c2184a8d1c6e9d1f65d7f 919 SUPERFAMILY SSF141571 668 782 1.83E-16 T 12-10-2018 MIM_c28750 2616a15aa44c2184a8d1c6e9d1f65d7f 919 Gene3D G3DSA:2.160.20.100 822 900 5.9E-16 T 12-10-2018 MIM_c28750 2616a15aa44c2184a8d1c6e9d1f65d7f 919 SUPERFAMILY SSF141571 786 894 5.76E-25 T 12-10-2018 MIM_c28750 2616a15aa44c2184a8d1c6e9d1f65d7f 919 Pfam PF00805 Pentapeptide repeats (8 copies) 613 652 2.5E-10 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c28750 2616a15aa44c2184a8d1c6e9d1f65d7f 919 Pfam PF00805 Pentapeptide repeats (8 copies) 820 858 1.3E-7 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c28750 2616a15aa44c2184a8d1c6e9d1f65d7f 919 Pfam PF00805 Pentapeptide repeats (8 copies) 860 892 1.5E-5 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c28750 2616a15aa44c2184a8d1c6e9d1f65d7f 919 Pfam PF00805 Pentapeptide repeats (8 copies) 653 692 3.3E-7 T 12-10-2018 IPR001646 Pentapeptide repeat MIM_c28750 2616a15aa44c2184a8d1c6e9d1f65d7f 919 Gene3D G3DSA:2.160.20.100 701 821 3.8E-20 T 12-10-2018 MIM_c03280 176814fa035c68ffe4b00762f319e60b 535 SUPERFAMILY SSF52096 276 535 7.55E-89 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c03280 176814fa035c68ffe4b00762f319e60b 535 SUPERFAMILY SSF52096 22 267 9.96E-71 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c03280 176814fa035c68ffe4b00762f319e60b 535 Gene3D G3DSA:3.90.226.10 1 272 1.0E-94 T 12-10-2018 MIM_c03280 176814fa035c68ffe4b00762f319e60b 535 Gene3D G3DSA:3.90.226.10 274 535 4.2E-106 T 12-10-2018 MIM_c03280 176814fa035c68ffe4b00762f319e60b 535 Pfam PF01039 Carboxyl transferase domain 48 525 3.8E-151 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 MIM_c21630 8afd2bf000b0ba4ae02c9eef164807ba 269 Pfam PF12697 Alpha/beta hydrolase family 20 260 9.4E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c21630 8afd2bf000b0ba4ae02c9eef164807ba 269 SUPERFAMILY SSF53474 14 264 3.94E-19 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c21630 8afd2bf000b0ba4ae02c9eef164807ba 269 Gene3D G3DSA:3.40.50.1820 11 267 2.3E-30 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c18010 98838e2873adbe918a3329619c41ca16 70 Gene3D G3DSA:1.20.5.1150 16 54 8.9E-20 T 12-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c18010 98838e2873adbe918a3329619c41ca16 70 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 4.0E-15 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c18010 98838e2873adbe918a3329619c41ca16 70 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 4.0E-15 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c18010 98838e2873adbe918a3329619c41ca16 70 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 4.0E-15 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c18010 98838e2873adbe918a3329619c41ca16 70 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 4.0E-15 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c18010 98838e2873adbe918a3329619c41ca16 70 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 3.6E-23 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c18010 98838e2873adbe918a3329619c41ca16 70 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 57 1.0E-16 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c18010 98838e2873adbe918a3329619c41ca16 70 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 20.2 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c18010 98838e2873adbe918a3329619c41ca16 70 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 12-10-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c18010 98838e2873adbe918a3329619c41ca16 70 Pfam PF01165 Ribosomal protein S21 4 57 1.0E-20 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c01830 412b0d7d5ff2d9dacf53b74364df6ad3 273 Gene3D G3DSA:3.40.50.300 6 256 4.9E-60 T 12-10-2018 MIM_c01830 412b0d7d5ff2d9dacf53b74364df6ad3 273 SUPERFAMILY SSF52540 9 233 2.51E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c01830 412b0d7d5ff2d9dacf53b74364df6ad3 273 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c01830 412b0d7d5ff2d9dacf53b74364df6ad3 273 SMART SM00382 32 216 1.3E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c01830 412b0d7d5ff2d9dacf53b74364df6ad3 273 Pfam PF00005 ABC transporter 29 167 6.1E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c30210 801e29db7cf8f1d5f7f920ca2a5cda29 332 SUPERFAMILY SSF53474 68 329 1.15E-27 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c30210 801e29db7cf8f1d5f7f920ca2a5cda29 332 Pfam PF00561 alpha/beta hydrolase fold 84 247 6.9E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c30210 801e29db7cf8f1d5f7f920ca2a5cda29 332 Gene3D G3DSA:3.40.50.1820 13 332 3.6E-88 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c26340 fe65a90f3405078801f26f1a454c551b 224 Pfam PF00308 Bacterial dnaA protein 85 200 7.2E-6 T 12-10-2018 IPR013317 Chromosomal replication initiator protein DnaA MIM_c26340 fe65a90f3405078801f26f1a454c551b 224 Gene3D G3DSA:1.10.8.60 155 220 4.9E-23 T 12-10-2018 MIM_c26340 fe65a90f3405078801f26f1a454c551b 224 SUPERFAMILY SSF52540 18 207 7.24E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c26340 fe65a90f3405078801f26f1a454c551b 224 TIGRFAM TIGR03420 DnaA_homol_Hda: DnaA regulatory inactivator Hda 4 220 5.5E-59 T 12-10-2018 IPR017788 DnaA regulatory inactivator Hda GO:0032297 MIM_c26340 fe65a90f3405078801f26f1a454c551b 224 Gene3D G3DSA:3.40.50.300 27 151 4.2E-19 T 12-10-2018 MIM_c20680 fdc1ff86018cd6cece27960158b50b3c 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.2E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20680 fdc1ff86018cd6cece27960158b50b3c 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.2E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20680 fdc1ff86018cd6cece27960158b50b3c 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.2E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20680 fdc1ff86018cd6cece27960158b50b3c 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 242 1.4E-50 T 12-10-2018 MIM_c20680 fdc1ff86018cd6cece27960158b50b3c 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c20680 fdc1ff86018cd6cece27960158b50b3c 248 Gene3D G3DSA:3.40.50.720 1 247 7.1E-63 T 12-10-2018 MIM_c20680 fdc1ff86018cd6cece27960158b50b3c 248 SUPERFAMILY SSF51735 2 245 5.97E-63 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c20680 fdc1ff86018cd6cece27960158b50b3c 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 7.4E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20680 fdc1ff86018cd6cece27960158b50b3c 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 7.4E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20680 fdc1ff86018cd6cece27960158b50b3c 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 7.4E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20680 fdc1ff86018cd6cece27960158b50b3c 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 7.4E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20680 fdc1ff86018cd6cece27960158b50b3c 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 7.4E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c20680 fdc1ff86018cd6cece27960158b50b3c 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 7.4E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c38740 ff9b1fa8ede10739f616dbe86c004fdd 297 SUPERFAMILY SSF161098 94 278 2.22E-26 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c38740 ff9b1fa8ede10739f616dbe86c004fdd 297 Gene3D G3DSA:1.10.3720.10 87 288 1.8E-22 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c38740 ff9b1fa8ede10739f616dbe86c004fdd 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 292 4.5E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c37780 8ecd49a891a5577626904500c9463548 1264 Pfam PF13524 Glycosyl transferases group 1 673 753 1.3E-6 T 12-10-2018 MIM_c37780 8ecd49a891a5577626904500c9463548 1264 Pfam PF12996 DUF based on E. rectale Gene description (DUF3880) 524 587 1.6E-7 T 12-10-2018 IPR024542 Domain of unknown function DUF3880 MIM_c05740 84123049d002d52f512d8c5da182614c 294 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 88 276 5.1E-13 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c05740 84123049d002d52f512d8c5da182614c 294 Gene3D G3DSA:3.40.190.10 146 235 1.2E-15 T 12-10-2018 MIM_c05740 84123049d002d52f512d8c5da182614c 294 Gene3D G3DSA:3.40.190.10 88 275 1.2E-15 T 12-10-2018 MIM_c05740 84123049d002d52f512d8c5da182614c 294 SUPERFAMILY SSF53850 83 275 2.78E-19 T 12-10-2018 MIM_c31890 1953ed279e70b4c14460fc28b8dad057 111 SUPERFAMILY SSF53098 8 107 2.28E-27 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily MIM_c31890 1953ed279e70b4c14460fc28b8dad057 111 Gene3D G3DSA:3.30.420.10 1 110 1.6E-16 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MIM_c31890 1953ed279e70b4c14460fc28b8dad057 111 Pfam PF13683 Integrase core domain 38 103 3.5E-23 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 MIM_c02020 2c8e28fdb4ccfeec3082c56f3a104923 255 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c02020 2c8e28fdb4ccfeec3082c56f3a104923 255 Pfam PF00005 ABC transporter 38 183 3.4E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c02020 2c8e28fdb4ccfeec3082c56f3a104923 255 PIRSF PIRSF039137 18 255 7.8E-101 T 12-10-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 MIM_c02020 2c8e28fdb4ccfeec3082c56f3a104923 255 SUPERFAMILY SSF52540 20 253 2.88E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c02020 2c8e28fdb4ccfeec3082c56f3a104923 255 Gene3D G3DSA:3.40.50.300 18 255 4.4E-65 T 12-10-2018 MIM_c02020 2c8e28fdb4ccfeec3082c56f3a104923 255 SMART SM00382 47 253 1.5E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c32720 583c24d520d7b04dd61ac9520759323d 258 Pfam PF04199 Putative cyclase 19 195 1.4E-29 T 12-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 MIM_c32720 583c24d520d7b04dd61ac9520759323d 258 Gene3D G3DSA:3.50.30.50 1 258 2.2E-87 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 MIM_c32720 583c24d520d7b04dd61ac9520759323d 258 SUPERFAMILY SSF102198 16 256 6.67E-51 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 MIM_c20840 fe8e46e1fc3fb8c8337e9d29902fe262 324 PIRSF PIRSF017082 2 320 2.3E-78 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c20840 fe8e46e1fc3fb8c8337e9d29902fe262 324 SUPERFAMILY SSF53850 117 288 1.87E-13 T 12-10-2018 MIM_c20840 fe8e46e1fc3fb8c8337e9d29902fe262 324 Gene3D G3DSA:3.40.190.150 33 314 7.5E-100 T 12-10-2018 MIM_c20840 fe8e46e1fc3fb8c8337e9d29902fe262 324 Gene3D G3DSA:3.40.190.10 129 252 7.5E-100 T 12-10-2018 MIM_c20840 fe8e46e1fc3fb8c8337e9d29902fe262 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 316 6.5E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c06940 afbf3dbc2ab07766d554d74cc5053fd2 133 Pfam PF04138 GtrA-like protein 11 128 7.3E-17 T 12-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 MIM_c02700 1df71bcb6ee97b095c97f97da58f411a 320 PIRSF PIRSF017082 2 320 1.2E-80 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c02700 1df71bcb6ee97b095c97f97da58f411a 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 316 1.7E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c02700 1df71bcb6ee97b095c97f97da58f411a 320 Gene3D G3DSA:3.40.190.150 26 310 7.9E-105 T 12-10-2018 MIM_c02700 1df71bcb6ee97b095c97f97da58f411a 320 SUPERFAMILY SSF53850 112 281 2.38E-11 T 12-10-2018 MIM_c02700 1df71bcb6ee97b095c97f97da58f411a 320 Gene3D G3DSA:3.40.190.10 124 245 7.9E-105 T 12-10-2018 MIM_c04150 6e3139a2492bd606f2c99521ffa46c9b 172 Pfam PF07883 Cupin domain 82 145 8.9E-11 T 12-10-2018 IPR013096 Cupin 2, conserved barrel MIM_c04150 6e3139a2492bd606f2c99521ffa46c9b 172 Gene3D G3DSA:2.60.120.10 41 171 1.3E-47 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c04150 6e3139a2492bd606f2c99521ffa46c9b 172 SUPERFAMILY SSF51182 56 170 1.87E-29 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c17640 217217c642e4bd05487e571bc84eb8a7 323 Gene3D G3DSA:3.40.190.10 125 248 3.3E-97 T 12-10-2018 MIM_c17640 217217c642e4bd05487e571bc84eb8a7 323 SUPERFAMILY SSF53850 110 283 1.41E-7 T 12-10-2018 MIM_c17640 217217c642e4bd05487e571bc84eb8a7 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 318 7.1E-80 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c17640 217217c642e4bd05487e571bc84eb8a7 323 Gene3D G3DSA:3.40.190.150 27 313 3.3E-97 T 12-10-2018 MIM_c17640 217217c642e4bd05487e571bc84eb8a7 323 PIRSF PIRSF017082 1 323 9.2E-72 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c15760 a0e0e144c45a7a3540f2ce77cc3e2aeb 99 Pfam PF12112 Protein of unknown function (DUF3579) 6 96 3.1E-38 T 12-10-2018 IPR021969 Protein of unknown function DUF3579 MIM_c15760 a0e0e144c45a7a3540f2ce77cc3e2aeb 99 Gene3D G3DSA:3.30.70.2340 2 99 2.7E-36 T 12-10-2018 MIM_c10960 cf61a36d534b169a362a8a6b47e8999a 908 TIGRFAM TIGR02675 tape_meas_nterm: tape measure domain 139 211 3.7E-19 T 12-10-2018 IPR013491 Caudovirus, tape measure, N-terminal MIM_c27280 76ad342e5e09625d29e0ab81dface453 305 Pfam PF05853 beta-keto acid cleavage enzyme 5 292 1.8E-89 T 12-10-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247 MIM_c27280 76ad342e5e09625d29e0ab81dface453 305 Gene3D G3DSA:3.20.20.70 4 296 8.0E-89 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c38040 c1b95078c9deb67b2f1dcfec63051acc 184 Pfam PF04965 Gene 25-like lysozyme 54 158 2.2E-22 T 12-10-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD MIM_c38040 c1b95078c9deb67b2f1dcfec63051acc 184 TIGRFAM TIGR03357 VI_zyme: type VI secretion system lysozyme-like protein 27 177 8.8E-19 T 12-10-2018 IPR017737 Type VI secretion system, lysozyme-related protein MIM_c38040 c1b95078c9deb67b2f1dcfec63051acc 184 SUPERFAMILY SSF160719 55 169 2.75E-9 T 12-10-2018 MIM_c11270 e335c9d55136532551bcbedcdf24e8f4 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 42 218 5.7E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c11270 e335c9d55136532551bcbedcdf24e8f4 229 SUPERFAMILY SSF161098 4 229 6.28E-57 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c11270 e335c9d55136532551bcbedcdf24e8f4 229 Gene3D G3DSA:1.10.3720.10 1 216 8.2E-51 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c37190 8d2a2651f6372a48d536ada137e41321 340 Pfam PF03812 2-keto-3-deoxygluconate permease 12 316 1.2E-105 T 12-10-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 MIM_c37190 8d2a2651f6372a48d536ada137e41321 340 ProDom PD024513 PERMEASE 2-KETO-3-DEOXYGLUCONATE MEMBRANE TRANSMEMBRANE SUGAR KDG SYMPORT INNER 2-KETO-3-DEOXY-D-GLUCONATE SYSTEM 34 316 1.0E-99 T 12-10-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 MIM_c19610 c657c026432769750c4a2d0e678deefe 353 Pfam PF13177 DNA polymerase III, delta subunit 22 190 2.7E-38 T 12-10-2018 MIM_c19610 c657c026432769750c4a2d0e678deefe 353 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 21 223 2.4E-59 T 12-10-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MIM_c19610 c657c026432769750c4a2d0e678deefe 353 SUPERFAMILY SSF52540 22 229 3.26E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c19610 c657c026432769750c4a2d0e678deefe 353 Gene3D G3DSA:3.40.50.300 11 191 4.9E-47 T 12-10-2018 MIM_c32180 d96f1a163e50cc01be1d7b391fec5b54 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 3.0E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c32180 d96f1a163e50cc01be1d7b391fec5b54 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 3.0E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c32180 d96f1a163e50cc01be1d7b391fec5b54 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 3.0E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c32180 d96f1a163e50cc01be1d7b391fec5b54 266 SUPERFAMILY SSF51735 11 262 1.3E-81 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c32180 d96f1a163e50cc01be1d7b391fec5b54 266 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c32180 d96f1a163e50cc01be1d7b391fec5b54 266 Pfam PF00106 short chain dehydrogenase 14 201 9.5E-62 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c32180 d96f1a163e50cc01be1d7b391fec5b54 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 9.3E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c32180 d96f1a163e50cc01be1d7b391fec5b54 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 9.3E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c32180 d96f1a163e50cc01be1d7b391fec5b54 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 9.3E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c32180 d96f1a163e50cc01be1d7b391fec5b54 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 9.3E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c32180 d96f1a163e50cc01be1d7b391fec5b54 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 9.3E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c32180 d96f1a163e50cc01be1d7b391fec5b54 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 9.3E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c32180 d96f1a163e50cc01be1d7b391fec5b54 266 Gene3D G3DSA:3.40.50.720 1 263 3.5E-86 T 12-10-2018 MIM_c32180 d96f1a163e50cc01be1d7b391fec5b54 266 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 13 183 0.0023 T 12-10-2018 MIM_c05100 a97b34d4b1fa256c4eeaab3d26be671c 175 SUPERFAMILY SSF46785 32 162 2.53E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c05100 a97b34d4b1fa256c4eeaab3d26be671c 175 Gene3D G3DSA:1.10.10.10 21 108 3.7E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c05100 a97b34d4b1fa256c4eeaab3d26be671c 175 Gene3D G3DSA:3.30.1490.190 110 169 2.5E-11 T 12-10-2018 MIM_c05100 a97b34d4b1fa256c4eeaab3d26be671c 175 Pfam PF01475 Ferric uptake regulator family 39 152 6.8E-17 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 MIM_c13070 2af8d9e070943c0431efa5e6005b71e9 232 Pfam PF04391 Protein of unknown function (DUF533) 41 229 8.0E-57 T 12-10-2018 IPR007486 Inner membrane protein YebE MIM_c13070 2af8d9e070943c0431efa5e6005b71e9 232 Gene3D G3DSA:1.10.3680.10 111 232 4.2E-9 T 12-10-2018 IPR029024 TerB-like MIM_c13070 2af8d9e070943c0431efa5e6005b71e9 232 SUPERFAMILY SSF158682 70 230 4.71E-22 T 12-10-2018 IPR029024 TerB-like MIM_c15900 b2ac4a7ad27c30ba935bdee880d4cb04 617 Pfam PF02470 MlaD protein 224 284 4.1E-9 T 12-10-2018 IPR003399 Mce/MlaD MIM_c15900 b2ac4a7ad27c30ba935bdee880d4cb04 617 Pfam PF02470 MlaD protein 360 464 5.7E-9 T 12-10-2018 IPR003399 Mce/MlaD MIM_c15900 b2ac4a7ad27c30ba935bdee880d4cb04 617 Pfam PF02470 MlaD protein 108 194 1.1E-9 T 12-10-2018 IPR003399 Mce/MlaD MIM_c31950 79b857bf05ca2cdef4869c7192e84161 296 Pfam PF06527 TniQ 8 134 1.8E-32 T 12-10-2018 IPR009492 TniQ MIM_c35500 53c236d236253f8d2f6f528f763bc55f 502 Gene3D G3DSA:3.40.190.10 183 486 7.5E-136 T 12-10-2018 MIM_c35500 53c236d236253f8d2f6f528f763bc55f 502 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 69 412 1.4E-96 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain MIM_c35500 53c236d236253f8d2f6f528f763bc55f 502 Gene3D G3DSA:3.10.105.10 258 476 7.5E-136 T 12-10-2018 MIM_c35500 53c236d236253f8d2f6f528f763bc55f 502 SUPERFAMILY SSF53850 27 501 8.91E-134 T 12-10-2018 MIM_c35500 53c236d236253f8d2f6f528f763bc55f 502 Gene3D G3DSA:3.90.76.10 35 182 7.5E-136 T 12-10-2018 MIM_c35500 53c236d236253f8d2f6f528f763bc55f 502 PIRSF PIRSF002741 19 502 9.2E-122 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MIM_c19680 4415ad431effe849fc71e47097bd5914 160 Pfam PF00255 Glutathione peroxidase 4 111 4.5E-42 T 12-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MIM_c19680 4415ad431effe849fc71e47097bd5914 160 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 60 67 - T 12-10-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 MIM_c19680 4415ad431effe849fc71e47097bd5914 160 PIRSF PIRSF000303 1 160 8.2E-65 T 12-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MIM_c19680 4415ad431effe849fc71e47097bd5914 160 Gene3D G3DSA:3.40.30.10 1 160 7.3E-69 T 12-10-2018 MIM_c19680 4415ad431effe849fc71e47097bd5914 160 PRINTS PR01011 Glutathione peroxidase family signature 22 39 2.9E-20 T 12-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MIM_c19680 4415ad431effe849fc71e47097bd5914 160 PRINTS PR01011 Glutathione peroxidase family signature 57 73 2.9E-20 T 12-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MIM_c19680 4415ad431effe849fc71e47097bd5914 160 PRINTS PR01011 Glutathione peroxidase family signature 123 132 2.9E-20 T 12-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MIM_c19680 4415ad431effe849fc71e47097bd5914 160 ProSitePatterns PS00460 Glutathione peroxidases active site. 24 39 - T 12-10-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 MIM_c19680 4415ad431effe849fc71e47097bd5914 160 SUPERFAMILY SSF52833 4 159 9.77E-60 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c26620 73c392b6c04564af6e57abdf9491a2f6 179 Pfam PF13242 HAD-hyrolase-like 99 162 3.8E-14 T 12-10-2018 MIM_c26620 73c392b6c04564af6e57abdf9491a2f6 179 SUPERFAMILY SSF56784 1 156 1.09E-45 T 12-10-2018 IPR036412 HAD-like superfamily MIM_c26620 73c392b6c04564af6e57abdf9491a2f6 179 PIRSF PIRSF004682 1 179 7.2E-56 T 12-10-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 MIM_c26620 73c392b6c04564af6e57abdf9491a2f6 179 Gene3D G3DSA:3.40.50.1000 1 179 6.6E-57 T 12-10-2018 IPR023214 HAD superfamily MIM_c26620 73c392b6c04564af6e57abdf9491a2f6 179 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 4 145 1.6E-43 T 12-10-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 MIM_c26620 73c392b6c04564af6e57abdf9491a2f6 179 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 2 146 1.4E-35 T 12-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 MIM_c30570 7bef4c315a622f1f92f1ec82b80fe6ba 313 Gene3D G3DSA:1.10.3720.10 85 307 1.2E-27 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c30570 7bef4c315a622f1f92f1ec82b80fe6ba 313 SUPERFAMILY SSF161098 91 298 1.96E-21 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c30570 7bef4c315a622f1f92f1ec82b80fe6ba 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 313 1.4E-44 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c33710 179bf4cd7f64cb946598c40c7a7c0cfe 346 Gene3D G3DSA:3.20.20.210 2 346 2.8E-132 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MIM_c33710 179bf4cd7f64cb946598c40c7a7c0cfe 346 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 9 333 2.7E-35 T 12-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MIM_c33710 179bf4cd7f64cb946598c40c7a7c0cfe 346 SUPERFAMILY SSF51726 11 344 2.75E-66 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MIM_c33710 179bf4cd7f64cb946598c40c7a7c0cfe 346 PIRSF PIRSF005632 1 346 1.4E-199 T 12-10-2018 IPR016456 Predicted cobalamin-independent methionine synthase, catalytic subunit MIM_c31540 93ea6857a3132ffedf8aa8cd6ffb50ae 217 Gene3D G3DSA:3.40.50.720 2 217 7.4E-60 T 12-10-2018 MIM_c31540 93ea6857a3132ffedf8aa8cd6ffb50ae 217 Pfam PF13460 NAD(P)H-binding 7 202 1.0E-36 T 12-10-2018 IPR016040 NAD(P)-binding domain MIM_c31540 93ea6857a3132ffedf8aa8cd6ffb50ae 217 SUPERFAMILY SSF51735 1 215 2.62E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c32560 31e80fcb6bd6c7d0322ee3928b0eee1b 440 Pfam PF03023 MviN-like protein 29 422 1.9E-30 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MIM_c16310 1f2cbcfbe27f3b9d2b5381e95901db9e 88 Pfam PF02643 Uncharacterized ACR, COG1430 1 70 5.0E-8 T 12-10-2018 IPR003795 Protein of unknown function DUF192 MIM_c03670 b2dcf2b8500f2f5e4cf28c7e5f04a76f 248 SMART SM00953 69 206 3.8E-28 T 12-10-2018 IPR014914 RES domain MIM_c03670 b2dcf2b8500f2f5e4cf28c7e5f04a76f 248 Pfam PF08808 RES domain 62 205 3.2E-22 T 12-10-2018 IPR014914 RES domain MIM_c17930 558c9455f97af2791e38b38c535e3f30 357 Gene3D G3DSA:3.40.640.10 38 264 6.6E-103 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c17930 558c9455f97af2791e38b38c535e3f30 357 Pfam PF00155 Aminotransferase class I and II 24 352 6.4E-57 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MIM_c17930 558c9455f97af2791e38b38c535e3f30 357 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 4 356 53.811 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 MIM_c17930 558c9455f97af2791e38b38c535e3f30 357 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 8 355 3.3E-89 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 MIM_c17930 558c9455f97af2791e38b38c535e3f30 357 Gene3D G3DSA:3.90.1150.10 21 345 6.6E-103 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c17930 558c9455f97af2791e38b38c535e3f30 357 SUPERFAMILY SSF53383 5 355 2.02E-74 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c17930 558c9455f97af2791e38b38c535e3f30 357 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 212 221 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 MIM_c22170 1b560c1fd05591ab46f9f98f43081049 209 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 13 206 4.5E-97 T 12-10-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 MIM_c22170 1b560c1fd05591ab46f9f98f43081049 209 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 15 185 1.0E-36 T 12-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain MIM_c22170 1b560c1fd05591ab46f9f98f43081049 209 PIRSF PIRSF005624 3 208 4.6E-50 T 12-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 MIM_c22170 1b560c1fd05591ab46f9f98f43081049 209 Hamap MF_01389 Urease accessory protein UreG [ureG]. 11 209 46.322 T 12-10-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 MIM_c22170 1b560c1fd05591ab46f9f98f43081049 209 SUPERFAMILY SSF52540 11 204 6.56E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c22170 1b560c1fd05591ab46f9f98f43081049 209 Gene3D G3DSA:3.40.50.300 12 208 1.4E-49 T 12-10-2018 MIM_c41080 cd4c7175895199ff3ac9a9ba2700b688 306 Gene3D G3DSA:2.60.130.10 13 195 1.8E-52 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 MIM_c41080 cd4c7175895199ff3ac9a9ba2700b688 306 Pfam PF00775 Dioxygenase 52 174 9.9E-14 T 12-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 MIM_c41080 cd4c7175895199ff3ac9a9ba2700b688 306 SUPERFAMILY SSF49482 38 198 3.53E-51 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 MIM_c02330 ff1a7ecd0a72e4f419edd3a7fde7df84 250 Gene3D G3DSA:1.10.760.10 143 250 3.2E-21 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c02330 ff1a7ecd0a72e4f419edd3a7fde7df84 250 SUPERFAMILY SSF46626 149 246 1.39E-23 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c02330 ff1a7ecd0a72e4f419edd3a7fde7df84 250 Pfam PF03640 Secreted repeat of unknown function 99 132 8.7E-11 T 12-10-2018 IPR005297 Lipoprotein repeat MIM_c02330 ff1a7ecd0a72e4f419edd3a7fde7df84 250 PRINTS PR00605 Class IC cytochrome C signature 170 181 4.1E-7 T 12-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 MIM_c02330 ff1a7ecd0a72e4f419edd3a7fde7df84 250 PRINTS PR00605 Class IC cytochrome C signature 208 230 4.1E-7 T 12-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 MIM_c02330 ff1a7ecd0a72e4f419edd3a7fde7df84 250 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 160 230 4.9E-15 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c02860 1b04b9a2d044dd5960d9acb0df1c0d25 418 SUPERFAMILY SSF103473 10 407 3.92E-55 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c02860 1b04b9a2d044dd5960d9acb0df1c0d25 418 ProSitePatterns PS00216 Sugar transport proteins signature 1. 75 91 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MIM_c02860 1b04b9a2d044dd5960d9acb0df1c0d25 418 Pfam PF07690 Major Facilitator Superfamily 31 367 1.1E-37 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c02860 1b04b9a2d044dd5960d9acb0df1c0d25 418 Gene3D G3DSA:1.20.1720.10 20 398 1.1E-64 T 12-10-2018 MIM_c06250 7084e3f6398c5afdd00acdeba6f4cace 335 PIRSF PIRSF017082 1 334 2.8E-71 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c06250 7084e3f6398c5afdd00acdeba6f4cace 335 Gene3D G3DSA:3.40.190.150 38 325 1.8E-95 T 12-10-2018 MIM_c06250 7084e3f6398c5afdd00acdeba6f4cace 335 Gene3D G3DSA:3.40.190.10 135 261 1.8E-95 T 12-10-2018 MIM_c06250 7084e3f6398c5afdd00acdeba6f4cace 335 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 57 331 1.0E-72 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c06460 b82d50adc7588493ea4190fbcb5c39ea 344 TIGRFAM TIGR03347 VI_chp_1: type VI secretion protein, VC_A0111 family 25 322 3.3E-98 T 12-10-2018 IPR010732 Type VI secretion, TssG-like MIM_c06460 b82d50adc7588493ea4190fbcb5c39ea 344 Pfam PF06996 Type VI secretion, TssG 26 322 3.4E-100 T 12-10-2018 IPR010732 Type VI secretion, TssG-like MIM_c07450 8e6dffd55ac303bd1d4ade9cbbae0d80 200 Pfam PF03899 ATP synthase I chain 88 184 1.9E-6 T 12-10-2018 IPR005598 ATP synthase protein I MIM_c00730 75c6daca02d1ddcccff234d1f1a9e2b2 447 SMART SM00382 169 374 1.5E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c00730 75c6daca02d1ddcccff234d1f1a9e2b2 447 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 21 444 1.9E-141 T 12-10-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MIM_c00730 75c6daca02d1ddcccff234d1f1a9e2b2 447 SUPERFAMILY SSF52540 102 372 9.21E-83 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c00730 75c6daca02d1ddcccff234d1f1a9e2b2 447 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 357 366 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MIM_c00730 75c6daca02d1ddcccff234d1f1a9e2b2 447 Gene3D G3DSA:3.40.50.12240 21 446 1.9E-128 T 12-10-2018 MIM_c00730 75c6daca02d1ddcccff234d1f1a9e2b2 447 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 157 366 3.6E-70 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MIM_c26120 c35361e114648fdfa3cfd12e4d072ada 202 Hamap MF_00017 Recombination protein RecR [recR]. 1 202 87.547 T 12-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 MIM_c26120 c35361e114648fdfa3cfd12e4d072ada 202 Gene3D G3DSA:3.40.1360.10 81 201 6.1E-40 T 12-10-2018 MIM_c26120 c35361e114648fdfa3cfd12e4d072ada 202 Pfam PF13662 Toprim domain 85 175 2.6E-22 T 12-10-2018 IPR006171 TOPRIM domain MIM_c26120 c35361e114648fdfa3cfd12e4d072ada 202 Pfam PF02132 RecR protein 44 82 1.1E-11 T 12-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger MIM_c26120 c35361e114648fdfa3cfd12e4d072ada 202 TIGRFAM TIGR00615 recR: recombination protein RecR 8 200 1.8E-67 T 12-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 MIM_c26120 c35361e114648fdfa3cfd12e4d072ada 202 SMART SM00493 84 169 6.4E-6 T 12-10-2018 IPR006171 TOPRIM domain MIM_c26120 c35361e114648fdfa3cfd12e4d072ada 202 SUPERFAMILY SSF111304 8 200 3.92E-69 T 12-10-2018 IPR023627 Recombination protein RecR MIM_c26120 c35361e114648fdfa3cfd12e4d072ada 202 Gene3D G3DSA:1.10.8.420 6 57 1.1E-16 T 12-10-2018 MIM_c34110 df5087c30763d9dd4fcd13311e2935f3 184 Gene3D G3DSA:3.30.300.20 10 172 8.4E-30 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta MIM_c34110 df5087c30763d9dd4fcd13311e2935f3 184 SUPERFAMILY SSF82784 15 180 1.96E-29 T 12-10-2018 IPR036102 OsmC/Ohr superfamily MIM_c34110 df5087c30763d9dd4fcd13311e2935f3 184 Pfam PF02566 OsmC-like protein 72 180 3.2E-22 T 12-10-2018 IPR003718 OsmC/Ohr family MIM_c24500 5c095e855da41265d9d0e3e3b61d4b62 212 Gene3D G3DSA:1.20.120.1200 3 163 3.5E-36 T 12-10-2018 MIM_c24500 5c095e855da41265d9d0e3e3b61d4b62 212 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 19 161 1.1E-30 T 12-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c05880 76b68ccc752ba921c8a25cfb47b0464e 323 Gene3D G3DSA:3.60.20.30 190 323 5.8E-53 T 12-10-2018 MIM_c05880 76b68ccc752ba921c8a25cfb47b0464e 323 Pfam PF01112 Asparaginase 5 321 1.4E-116 T 12-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 MIM_c05880 76b68ccc752ba921c8a25cfb47b0464e 323 SUPERFAMILY SSF56235 4 319 1.0E-93 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MIM_c06530 0af3a153c57ae8b1bae91264dbddecad 1203 Pfam PF14331 ImcF-related N-terminal domain 210 471 1.8E-93 T 12-10-2018 IPR025743 ImcF-related, N-terminal domain MIM_c06530 0af3a153c57ae8b1bae91264dbddecad 1203 Pfam PF06744 Type VI secretion protein IcmF C-terminal 955 1151 2.8E-57 T 12-10-2018 IPR010623 Type VI secretion system IcmF, C-terminal MIM_c06530 0af3a153c57ae8b1bae91264dbddecad 1203 SUPERFAMILY SSF52540 127 308 2.25E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c06530 0af3a153c57ae8b1bae91264dbddecad 1203 Pfam PF06761 Intracellular multiplication and human macrophage-killing 524 830 2.8E-82 T 12-10-2018 IPR009612 ImcF-related MIM_c06530 0af3a153c57ae8b1bae91264dbddecad 1203 TIGRFAM TIGR03348 VI_IcmF: type VI secretion protein IcmF 15 1201 0.0 T 12-10-2018 IPR017731 Type VI secretion system, IcmF MIM_c32070 d8fec2b312ca566ca5e0b2b774d71e43 274 SMART SM00934 17 257 1.9E-49 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MIM_c32070 d8fec2b312ca566ca5e0b2b774d71e43 274 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 17 251 1.3E-30 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MIM_c32070 d8fec2b312ca566ca5e0b2b774d71e43 274 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 90 103 - T 12-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MIM_c32070 d8fec2b312ca566ca5e0b2b774d71e43 274 SUPERFAMILY SSF51366 3 270 3.33E-74 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MIM_c32070 d8fec2b312ca566ca5e0b2b774d71e43 274 Gene3D G3DSA:3.20.20.70 1 273 5.9E-97 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c32070 d8fec2b312ca566ca5e0b2b774d71e43 274 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 3 254 6.2E-71 T 12-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MIM_c32070 d8fec2b312ca566ca5e0b2b774d71e43 274 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 2 270 33.786 T 12-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MIM_c39380 76222e23bd19a6a3a1c875020e7ef3c7 284 SUPERFAMILY SSF51658 1 259 3.93E-77 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily MIM_c39380 76222e23bd19a6a3a1c875020e7ef3c7 284 Pfam PF01261 Xylose isomerase-like TIM barrel 22 220 2.0E-25 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MIM_c39380 76222e23bd19a6a3a1c875020e7ef3c7 284 Gene3D G3DSA:3.20.20.150 1 264 5.9E-73 T 12-10-2018 MIM_c39380 76222e23bd19a6a3a1c875020e7ef3c7 284 PIRSF PIRSF006241 1 263 1.2E-90 T 12-10-2018 IPR026040 Hydroxypyruvate isomerase-like MIM_c08510 53babdf2c365bbcb19716401569a2ba9 330 Gene3D G3DSA:3.40.190.150 34 320 1.6E-104 T 12-10-2018 MIM_c08510 53babdf2c365bbcb19716401569a2ba9 330 SUPERFAMILY SSF53850 118 288 5.43E-13 T 12-10-2018 MIM_c08510 53babdf2c365bbcb19716401569a2ba9 330 PIRSF PIRSF017082 1 329 3.1E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c08510 53babdf2c365bbcb19716401569a2ba9 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 323 1.6E-81 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c08510 53babdf2c365bbcb19716401569a2ba9 330 Gene3D G3DSA:3.40.190.10 132 253 1.6E-104 T 12-10-2018 MIM_c24240 ab5a02fe56fba319c2544585834f63d9 130 Gene3D G3DSA:2.170.150.20 1 130 8.4E-63 T 12-10-2018 MIM_c24240 ab5a02fe56fba319c2544585834f63d9 130 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 5 129 2.3E-58 T 12-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 MIM_c24240 ab5a02fe56fba319c2544585834f63d9 130 SUPERFAMILY SSF51316 4 129 2.14E-61 T 12-10-2018 IPR011057 Mss4-like superfamily MIM_c24240 ab5a02fe56fba319c2544585834f63d9 130 Pfam PF01641 SelR domain 9 128 5.1E-56 T 12-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 MIM_c24240 ab5a02fe56fba319c2544585834f63d9 130 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 6 129 39.385 T 12-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 MIM_c26770 b199d49b2aa543c31a6902e1854d1f8e 386 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 9 236 3.8E-22 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MIM_c08850 4646365653dbd488d21dc82ba48eb51b 206 TIGRFAM TIGR02081 metW: methionine biosynthesis protein MetW 11 198 6.5E-80 T 12-10-2018 IPR010743 Methionine biosynthesis MetW KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 MIM_c08850 4646365653dbd488d21dc82ba48eb51b 206 Gene3D G3DSA:3.40.50.150 19 200 3.3E-25 T 12-10-2018 MIM_c08850 4646365653dbd488d21dc82ba48eb51b 206 SUPERFAMILY SSF53335 14 187 4.11E-29 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c08850 4646365653dbd488d21dc82ba48eb51b 206 Pfam PF07021 Methionine biosynthesis protein MetW 11 196 1.8E-71 T 12-10-2018 IPR010743 Methionine biosynthesis MetW KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 MIM_c03700 e2463a9efa3507397933c16b0039a6ea 306 Gene3D G3DSA:3.10.310.50 23 169 3.3E-49 T 12-10-2018 MIM_c03700 e2463a9efa3507397933c16b0039a6ea 306 Pfam PF04536 TPM domain 38 160 1.1E-39 T 12-10-2018 IPR007621 TPM domain MIM_c40510 7506da96daecd6550b2ee04f8d9952f1 273 SUPERFAMILY SSF56214 86 162 1.28E-14 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MIM_c40510 7506da96daecd6550b2ee04f8d9952f1 273 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 87 163 1.2E-10 T 12-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MIM_c40510 7506da96daecd6550b2ee04f8d9952f1 273 Gene3D G3DSA:3.90.470.20 87 170 1.3E-14 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MIM_c19990 8a0ff12e38e5e37d896c5ba96b3c298a 223 SUPERFAMILY SSF89562 29 181 2.35E-38 T 12-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily MIM_c19990 8a0ff12e38e5e37d896c5ba96b3c298a 223 Pfam PF03737 Aldolase/RraA 33 172 1.2E-29 T 12-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MIM_c19990 8a0ff12e38e5e37d896c5ba96b3c298a 223 Gene3D G3DSA:3.50.30.100 14 195 4.5E-40 T 12-10-2018 MIM_c35930 6f491d1fff4ba89fb3c689992da68026 279 SUPERFAMILY SSF56300 9 250 1.17E-56 T 12-10-2018 MIM_c35930 6f491d1fff4ba89fb3c689992da68026 279 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 7 262 37.552 T 12-10-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 MIM_c35930 6f491d1fff4ba89fb3c689992da68026 279 Pfam PF00149 Calcineurin-like phosphoesterase 10 203 8.0E-21 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MIM_c35930 6f491d1fff4ba89fb3c689992da68026 279 Gene3D G3DSA:3.60.21.40 8 246 6.8E-91 T 12-10-2018 MIM_c35930 6f491d1fff4ba89fb3c689992da68026 279 Gene3D G3DSA:3.30.750.180 110 237 6.8E-91 T 12-10-2018 MIM_c20420 533bdcbbb2c471242b7f0ac4eed9489b 328 Gene3D G3DSA:3.40.190.10 127 250 1.9E-93 T 12-10-2018 MIM_c20420 533bdcbbb2c471242b7f0ac4eed9489b 328 PIRSF PIRSF017082 1 326 2.6E-68 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c20420 533bdcbbb2c471242b7f0ac4eed9489b 328 Gene3D G3DSA:3.40.190.150 29 319 1.9E-93 T 12-10-2018 MIM_c20420 533bdcbbb2c471242b7f0ac4eed9489b 328 SUPERFAMILY SSF53850 114 280 9.29E-9 T 12-10-2018 MIM_c20420 533bdcbbb2c471242b7f0ac4eed9489b 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 324 5.5E-62 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c38230 67320d32ac9ee174c08a3bda4abb038e 263 Gene3D G3DSA:3.40.50.80 138 263 1.2E-38 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MIM_c38230 67320d32ac9ee174c08a3bda4abb038e 263 Pfam PF08021 Siderophore-interacting FAD-binding domain 24 136 1.1E-36 T 12-10-2018 IPR013113 FAD-binding 9, siderophore-interacting MIM_c38230 67320d32ac9ee174c08a3bda4abb038e 263 SUPERFAMILY SSF63380 13 141 2.15E-16 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MIM_c38230 67320d32ac9ee174c08a3bda4abb038e 263 Pfam PF04954 Siderophore-interacting protein 144 258 8.2E-35 T 12-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain MIM_c38230 67320d32ac9ee174c08a3bda4abb038e 263 Gene3D G3DSA:2.40.30.10 6 137 3.8E-44 T 12-10-2018 MIM_c37480 de721eee31950ca1847085eb37bc2487 241 Pfam PF00005 ABC transporter 17 165 2.4E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c37480 de721eee31950ca1847085eb37bc2487 241 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c37480 de721eee31950ca1847085eb37bc2487 241 SUPERFAMILY SSF52540 1 235 6.05E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c37480 de721eee31950ca1847085eb37bc2487 241 SMART SM00382 26 213 1.6E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c37480 de721eee31950ca1847085eb37bc2487 241 Gene3D G3DSA:3.40.50.300 1 240 5.8E-78 T 12-10-2018 MIM_c37480 de721eee31950ca1847085eb37bc2487 241 PIRSF PIRSF039085 1 241 7.3E-103 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MIM_c10710 4f289e9c6032ec285d02268c2b255b22 147 Pfam PF05866 Endodeoxyribonuclease RusA 11 139 7.6E-35 T 12-10-2018 IPR008822 Holliday junction resolvase RusA-like GO:0000287|GO:0006281|GO:0006310 MIM_c10710 4f289e9c6032ec285d02268c2b255b22 147 Gene3D G3DSA:3.30.1330.70 5 143 1.0E-8 T 12-10-2018 IPR036614 Holliday junction resolvase RusA-like superfamily GO:0000287|GO:0006281|GO:0006310 MIM_c10710 4f289e9c6032ec285d02268c2b255b22 147 SUPERFAMILY SSF103084 6 139 1.09E-20 T 12-10-2018 IPR036614 Holliday junction resolvase RusA-like superfamily GO:0000287|GO:0006281|GO:0006310 MIM_c11990 a89d34789192e25ca10586d45d136bb1 248 Gene3D G3DSA:3.90.226.10 2 248 1.2E-66 T 12-10-2018 MIM_c11990 a89d34789192e25ca10586d45d136bb1 248 SUPERFAMILY SSF52096 3 248 7.07E-68 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c11990 a89d34789192e25ca10586d45d136bb1 248 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 246 8.7E-46 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c01220 5c249f9ad51847e2a4e4390387adb66f 485 Pfam PF06097 Bacterial protein of unknown function (DUF945) 1 469 6.5E-110 T 12-10-2018 IPR010352 Protein of unknown function DUF945 MIM_c00320 7dae4b5c2033fa578c94a735122181c9 322 Gene3D G3DSA:3.40.190.10 124 247 5.1E-115 T 12-10-2018 MIM_c00320 7dae4b5c2033fa578c94a735122181c9 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 318 8.4E-97 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c00320 7dae4b5c2033fa578c94a735122181c9 322 PIRSF PIRSF017082 1 322 3.8E-84 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c00320 7dae4b5c2033fa578c94a735122181c9 322 Gene3D G3DSA:3.40.190.150 26 312 5.1E-115 T 12-10-2018 MIM_c00320 7dae4b5c2033fa578c94a735122181c9 322 SUPERFAMILY SSF53850 113 280 9.72E-18 T 12-10-2018 MIM_c22870 ff1e880bc71d6788de47b646b3c3802e 186 Gene3D G3DSA:3.30.1330.60 57 186 2.6E-45 T 12-10-2018 IPR036737 OmpA-like domain superfamily MIM_c22870 ff1e880bc71d6788de47b646b3c3802e 186 Pfam PF00691 OmpA family 80 175 1.3E-26 T 12-10-2018 IPR006665 OmpA-like domain MIM_c22870 ff1e880bc71d6788de47b646b3c3802e 186 ProSitePatterns PS01068 OmpA-like domain. 113 157 - T 12-10-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 MIM_c22870 ff1e880bc71d6788de47b646b3c3802e 186 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 126 143 3.0E-10 T 12-10-2018 MIM_c22870 ff1e880bc71d6788de47b646b3c3802e 186 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 144 163 3.0E-10 T 12-10-2018 MIM_c22870 ff1e880bc71d6788de47b646b3c3802e 186 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 164 184 3.0E-10 T 12-10-2018 MIM_c22870 ff1e880bc71d6788de47b646b3c3802e 186 SUPERFAMILY SSF103088 72 181 5.76E-41 T 12-10-2018 IPR036737 OmpA-like domain superfamily MIM_c22870 ff1e880bc71d6788de47b646b3c3802e 186 PRINTS PR01021 OMPA domain signature 111 126 7.6E-23 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MIM_c22870 ff1e880bc71d6788de47b646b3c3802e 186 PRINTS PR01021 OMPA domain signature 81 103 7.6E-23 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MIM_c22870 ff1e880bc71d6788de47b646b3c3802e 186 PRINTS PR01021 OMPA domain signature 126 142 7.6E-23 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MIM_c30740 3917d705384ddd5577e9adc3f3f15f61 259 Gene3D G3DSA:3.40.50.720 6 258 4.5E-73 T 12-10-2018 MIM_c30740 3917d705384ddd5577e9adc3f3f15f61 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c30740 3917d705384ddd5577e9adc3f3f15f61 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 2.1E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c30740 3917d705384ddd5577e9adc3f3f15f61 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 2.1E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c30740 3917d705384ddd5577e9adc3f3f15f61 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 2.1E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c30740 3917d705384ddd5577e9adc3f3f15f61 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 2.1E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c30740 3917d705384ddd5577e9adc3f3f15f61 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 2.1E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c30740 3917d705384ddd5577e9adc3f3f15f61 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 2.1E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c30740 3917d705384ddd5577e9adc3f3f15f61 259 SUPERFAMILY SSF51735 14 257 5.52E-73 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c30740 3917d705384ddd5577e9adc3f3f15f61 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 256 1.7E-54 T 12-10-2018 MIM_c30740 3917d705384ddd5577e9adc3f3f15f61 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 2.1E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c30740 3917d705384ddd5577e9adc3f3f15f61 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 2.1E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c30740 3917d705384ddd5577e9adc3f3f15f61 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 2.1E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c05140 7917a74a959579ea4a87e35464901377 326 Gene3D G3DSA:1.10.443.10 114 311 1.6E-52 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MIM_c05140 7917a74a959579ea4a87e35464901377 326 SUPERFAMILY SSF56349 11 311 2.06E-50 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MIM_c05140 7917a74a959579ea4a87e35464901377 326 Pfam PF00589 Phage integrase family 116 303 1.4E-36 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MIM_c05140 7917a74a959579ea4a87e35464901377 326 Gene3D G3DSA:1.10.150.130 11 101 1.4E-15 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal MIM_c05140 7917a74a959579ea4a87e35464901377 326 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 11 317 55.331 T 12-10-2018 IPR023009 Tyrosine recombinase XerC/XerD MIM_c05140 7917a74a959579ea4a87e35464901377 326 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 14 89 6.5E-16 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MIM_c05140 7917a74a959579ea4a87e35464901377 326 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 14 318 4.7E-104 T 12-10-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007059|GO:0015074|GO:0051301 MIM_c29080 53d48cfa9f0c345edff712aacab15971 255 SUPERFAMILY SSF52218 3 231 6.39E-62 T 12-10-2018 IPR029039 Flavoprotein-like superfamily MIM_c29080 53d48cfa9f0c345edff712aacab15971 255 Pfam PF03358 NADPH-dependent FMN reductase 36 179 1.1E-25 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 MIM_c29080 53d48cfa9f0c345edff712aacab15971 255 Gene3D G3DSA:3.40.50.360 1 255 2.7E-87 T 12-10-2018 IPR029039 Flavoprotein-like superfamily MIM_c29080 53d48cfa9f0c345edff712aacab15971 255 TIGRFAM TIGR02690 resist_ArsH: arsenical resistance protein ArsH 30 227 1.3E-112 T 12-10-2018 IPR014063 Arsenate resistance ArsH MIM_c33940 7868a86fe848eb7db46963617ddadd27 88 Gene3D G3DSA:2.60.200.60 29 87 6.0E-9 T 12-10-2018 MIM_c33940 7868a86fe848eb7db46963617ddadd27 88 Pfam PF05488 PAAR motif 13 80 1.9E-19 T 12-10-2018 IPR008727 PAAR motif MIM_c29820 dd6692e375cb372ab1c9bc0f5c99b20e 149 ProDom PD003655 COPPER ELECTRON AZURIN METAL-BINDING PERIPLASMIC PRECURSOR SIGNAL SEQUENCING DIRECT MEMBRANE 26 145 4.0E-38 T 12-10-2018 MIM_c29820 dd6692e375cb372ab1c9bc0f5c99b20e 149 SUPERFAMILY SSF49503 22 147 5.46E-42 T 12-10-2018 IPR008972 Cupredoxin MIM_c29820 dd6692e375cb372ab1c9bc0f5c99b20e 149 TIGRFAM TIGR02695 azurin: azurin 23 147 1.1E-54 T 12-10-2018 IPR014068 Azurin MIM_c29820 dd6692e375cb372ab1c9bc0f5c99b20e 149 ProSitePatterns PS00196 Type-1 copper (blue) proteins signature. 125 141 - T 12-10-2018 IPR028871 Blue (type 1) copper protein, binding site MIM_c29820 dd6692e375cb372ab1c9bc0f5c99b20e 149 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 22 148 9.6E-23 T 12-10-2018 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 MIM_c29820 dd6692e375cb372ab1c9bc0f5c99b20e 149 Gene3D G3DSA:2.60.40.420 21 148 3.5E-43 T 12-10-2018 IPR008972 Cupredoxin MIM_c03540 0a2dee5fa229edbb72f7cecadc33a22a 1419 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 946 1010 5.0E-15 T 12-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 MIM_c03540 0a2dee5fa229edbb72f7cecadc33a22a 1419 Pfam PF09994 Uncharacterized alpha/beta hydrolase domain (DUF2235) 1012 1282 9.6E-22 T 12-10-2018 IPR018712 Domain of unknown function DUF2235 MIM_c03540 0a2dee5fa229edbb72f7cecadc33a22a 1419 Pfam PF05593 RHS Repeat 482 510 2.6E-5 T 12-10-2018 IPR031325 RHS repeat MIM_c03540 0a2dee5fa229edbb72f7cecadc33a22a 1419 PRINTS PR00394 RHS protein signature 954 974 6.6E-6 T 12-10-2018 IPR001826 RHS protein MIM_c03540 0a2dee5fa229edbb72f7cecadc33a22a 1419 PRINTS PR00394 RHS protein signature 977 996 6.6E-6 T 12-10-2018 IPR001826 RHS protein MIM_c03540 0a2dee5fa229edbb72f7cecadc33a22a 1419 PRINTS PR00394 RHS protein signature 901 921 6.6E-6 T 12-10-2018 IPR001826 RHS protein MIM_c03540 0a2dee5fa229edbb72f7cecadc33a22a 1419 Gene3D G3DSA:2.180.10.10 884 1010 1.1E-13 T 12-10-2018 MIM_c38120 265b3c5d2306e3e5e9278cb9627e687d 324 Gene3D G3DSA:3.40.190.170 24 324 1.7E-103 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily MIM_c38120 265b3c5d2306e3e5e9278cb9627e687d 324 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 34 290 8.2E-42 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 MIM_c02100 81a3873bf0bc7dabdbe62ea675820531 313 Pfam PF01545 Cation efflux family 27 240 8.0E-36 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MIM_c02100 81a3873bf0bc7dabdbe62ea675820531 313 Gene3D G3DSA:1.20.1510.10 20 240 3.5E-29 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily MIM_c02100 81a3873bf0bc7dabdbe62ea675820531 313 SUPERFAMILY SSF161111 18 241 1.57E-46 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily MIM_c02100 81a3873bf0bc7dabdbe62ea675820531 313 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 21 310 1.7E-63 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MIM_c16690 d5995717efa2cef64fd2621d2f94e1fa 502 SUPERFAMILY SSF63433 68 184 2.09E-27 T 12-10-2018 IPR036462 Fumarylacetoacetase, N-terminal domain superfamily GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 MIM_c16690 d5995717efa2cef64fd2621d2f94e1fa 502 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 190 468 4.6E-51 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 MIM_c16690 d5995717efa2cef64fd2621d2f94e1fa 502 Gene3D G3DSA:2.30.30.230 49 181 5.6E-28 T 12-10-2018 IPR036462 Fumarylacetoacetase, N-terminal domain superfamily GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 MIM_c16690 d5995717efa2cef64fd2621d2f94e1fa 502 Gene3D G3DSA:3.90.850.10 183 475 3.8E-109 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MIM_c16690 d5995717efa2cef64fd2621d2f94e1fa 502 SUPERFAMILY SSF56529 186 477 3.27E-89 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MIM_c16690 d5995717efa2cef64fd2621d2f94e1fa 502 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 68 473 3.1E-151 T 12-10-2018 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 MIM_c16690 d5995717efa2cef64fd2621d2f94e1fa 502 Pfam PF09298 Fumarylacetoacetase N-terminal 83 184 5.7E-18 T 12-10-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 MIM_c27440 96d94223f4cbb07213f56921370022e2 249 Pfam PF01925 Sulfite exporter TauE/SafE 9 237 3.9E-25 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MIM_c11940 ba5d1f050118645d350e1639d0a5d2d7 415 Pfam PF01266 FAD dependent oxidoreductase 3 400 7.1E-68 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MIM_c11940 ba5d1f050118645d350e1639d0a5d2d7 415 SUPERFAMILY SSF51905 2 404 1.55E-47 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c11940 ba5d1f050118645d350e1639d0a5d2d7 415 SUPERFAMILY SSF54373 271 363 1.01E-13 T 12-10-2018 MIM_c11940 ba5d1f050118645d350e1639d0a5d2d7 415 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 6.5E-6 T 12-10-2018 MIM_c11940 ba5d1f050118645d350e1639d0a5d2d7 415 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 273 289 6.5E-6 T 12-10-2018 MIM_c31870 2cb9735476a9c6f0afe417c6e09d43c2 325 PIRSF PIRSF017082 3 325 2.8E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c31870 2cb9735476a9c6f0afe417c6e09d43c2 325 SUPERFAMILY SSF53850 96 288 4.29E-15 T 12-10-2018 MIM_c31870 2cb9735476a9c6f0afe417c6e09d43c2 325 Gene3D G3DSA:3.40.190.150 31 316 2.7E-92 T 12-10-2018 MIM_c31870 2cb9735476a9c6f0afe417c6e09d43c2 325 Gene3D G3DSA:3.40.190.10 127 251 2.7E-92 T 12-10-2018 MIM_c31870 2cb9735476a9c6f0afe417c6e09d43c2 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 322 2.7E-74 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c14570 82f5f12da2926d40b1226123711604bb 544 Gene3D G3DSA:1.20.1720.10 28 260 1.4E-44 T 12-10-2018 MIM_c14570 82f5f12da2926d40b1226123711604bb 544 Pfam PF07690 Major Facilitator Superfamily 31 424 2.3E-49 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c14570 82f5f12da2926d40b1226123711604bb 544 Gene3D G3DSA:1.20.1250.20 273 442 8.2E-22 T 12-10-2018 MIM_c14570 82f5f12da2926d40b1226123711604bb 544 SUPERFAMILY SSF103473 27 519 8.11E-69 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c14570 82f5f12da2926d40b1226123711604bb 544 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 29 444 1.3E-69 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 MIM_c09990 3317203385c485381ea691ffa3a84617 345 Pfam PF05171 Haemin-degrading HemS.ChuX domain 33 157 1.6E-35 T 12-10-2018 IPR007845 Haemin-degrading HemS/ChuX domain GO:0006826 MIM_c09990 3317203385c485381ea691ffa3a84617 345 Pfam PF05171 Haemin-degrading HemS.ChuX domain 207 338 1.4E-40 T 12-10-2018 IPR007845 Haemin-degrading HemS/ChuX domain GO:0006826 MIM_c09990 3317203385c485381ea691ffa3a84617 345 Gene3D G3DSA:3.40.1570.10 11 281 1.9E-130 T 12-10-2018 MIM_c09990 3317203385c485381ea691ffa3a84617 345 SUPERFAMILY SSF144064 8 339 3.53E-121 T 12-10-2018 MIM_c09990 3317203385c485381ea691ffa3a84617 345 Gene3D G3DSA:3.40.1570.10 86 334 1.9E-130 T 12-10-2018 MIM_c08670 98f71ba4b84705ca3d53b561dee6b0ba 287 SUPERFAMILY SSF161098 4 276 3.64E-54 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c08670 98f71ba4b84705ca3d53b561dee6b0ba 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 23 278 1.2E-7 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c08670 98f71ba4b84705ca3d53b561dee6b0ba 287 Gene3D G3DSA:1.10.3720.10 7 279 1.1E-57 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c39120 b279bbfe50df6333aaa8d8a30eaba965 353 SUPERFAMILY SSF53850 32 351 1.04E-68 T 12-10-2018 MIM_c39120 b279bbfe50df6333aaa8d8a30eaba965 353 Gene3D G3DSA:3.40.190.10 135 337 4.0E-123 T 12-10-2018 MIM_c39120 b279bbfe50df6333aaa8d8a30eaba965 353 Gene3D G3DSA:3.40.190.10 35 331 4.0E-123 T 12-10-2018 MIM_c39120 b279bbfe50df6333aaa8d8a30eaba965 353 Pfam PF13416 Bacterial extracellular solute-binding protein 52 308 2.6E-45 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein MIM_c39120 b279bbfe50df6333aaa8d8a30eaba965 353 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 55 76 2.4E-5 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MIM_c39120 b279bbfe50df6333aaa8d8a30eaba965 353 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 99 112 2.4E-5 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MIM_c39120 b279bbfe50df6333aaa8d8a30eaba965 353 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 169 188 2.4E-5 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MIM_c39120 b279bbfe50df6333aaa8d8a30eaba965 353 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 299 325 2.4E-5 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MIM_c39120 b279bbfe50df6333aaa8d8a30eaba965 353 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 254 273 2.4E-5 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MIM_c08580 4a2931ff8799756e7c3ad86d9314f1d2 252 SUPERFAMILY SSF52096 1 246 5.57E-72 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c08580 4a2931ff8799756e7c3ad86d9314f1d2 252 Gene3D G3DSA:3.90.226.10 3 250 2.3E-71 T 12-10-2018 MIM_c08580 4a2931ff8799756e7c3ad86d9314f1d2 252 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 246 2.6E-48 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c15190 a2936cfd68b622ef002c2ffd4764b16d 374 Pfam PF00534 Glycosyl transferases group 1 182 346 3.3E-33 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 MIM_c15190 a2936cfd68b622ef002c2ffd4764b16d 374 Gene3D G3DSA:3.40.50.2000 173 347 1.8E-46 T 12-10-2018 MIM_c15190 a2936cfd68b622ef002c2ffd4764b16d 374 Pfam PF13439 Glycosyltransferase Family 4 24 171 3.6E-14 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MIM_c15190 a2936cfd68b622ef002c2ffd4764b16d 374 SUPERFAMILY SSF53756 17 366 1.06E-72 T 12-10-2018 MIM_c15190 a2936cfd68b622ef002c2ffd4764b16d 374 Gene3D G3DSA:3.40.50.2000 10 172 5.0E-15 T 12-10-2018 MIM_c18880 6e9dd8745797f26af47fa7e3d164699b 253 SUPERFAMILY SSF51735 7 237 1.39E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c18880 6e9dd8745797f26af47fa7e3d164699b 253 Gene3D G3DSA:3.40.50.720 7 253 1.1E-64 T 12-10-2018 MIM_c18880 6e9dd8745797f26af47fa7e3d164699b 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.1E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c18880 6e9dd8745797f26af47fa7e3d164699b 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.1E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c18880 6e9dd8745797f26af47fa7e3d164699b 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.1E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c18880 6e9dd8745797f26af47fa7e3d164699b 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.1E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c18880 6e9dd8745797f26af47fa7e3d164699b 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.0E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c18880 6e9dd8745797f26af47fa7e3d164699b 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.0E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c18880 6e9dd8745797f26af47fa7e3d164699b 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.0E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c18880 6e9dd8745797f26af47fa7e3d164699b 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MIM_c18880 6e9dd8745797f26af47fa7e3d164699b 253 Pfam PF00106 short chain dehydrogenase 7 200 3.3E-50 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c01040 78f59494ab3f635e65667ce1eae12023 520 SUPERFAMILY SSF56801 7 519 3.27E-132 T 12-10-2018 MIM_c01040 78f59494ab3f635e65667ce1eae12023 520 ProSitePatterns PS00455 Putative AMP-binding domain signature. 169 180 - T 12-10-2018 IPR020845 AMP-binding, conserved site MIM_c01040 78f59494ab3f635e65667ce1eae12023 520 Gene3D G3DSA:3.30.300.310 419 520 6.7E-29 T 12-10-2018 MIM_c01040 78f59494ab3f635e65667ce1eae12023 520 Pfam PF13193 AMP-binding enzyme C-terminal domain 432 507 5.7E-17 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MIM_c01040 78f59494ab3f635e65667ce1eae12023 520 Gene3D G3DSA:3.40.50.12780 2 416 5.7E-100 T 12-10-2018 MIM_c01040 78f59494ab3f635e65667ce1eae12023 520 Pfam PF00501 AMP-binding enzyme 15 421 3.8E-86 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MIM_c06200 143c92b060748ddfd5761c4881847f0c 281 Pfam PF03239 Iron permease FTR1 family 3 258 3.0E-22 T 12-10-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0016020|GO:0033573|GO:0034755 MIM_c27420 2d1d140c21eaa840b560ea30012f66db 112 Pfam PF03788 LrgA family 12 104 2.6E-20 T 12-10-2018 IPR005538 LrgA/CidA family GO:0016021 MIM_c26350 64707308d617be3d854396faa3c0ae13 226 Gene3D G3DSA:1.20.1440.100 17 91 4.6E-77 T 12-10-2018 MIM_c26350 64707308d617be3d854396faa3c0ae13 226 SUPERFAMILY SSF56784 2 217 3.01E-31 T 12-10-2018 IPR036412 HAD-like superfamily MIM_c26350 64707308d617be3d854396faa3c0ae13 226 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 5 196 5.1E-21 T 12-10-2018 MIM_c26350 64707308d617be3d854396faa3c0ae13 226 Gene3D G3DSA:3.40.50.1000 5 220 4.6E-77 T 12-10-2018 IPR023214 HAD superfamily MIM_c26350 64707308d617be3d854396faa3c0ae13 226 Pfam PF12710 haloacid dehalogenase-like hydrolase 6 194 5.0E-39 T 12-10-2018 MIM_c26350 64707308d617be3d854396faa3c0ae13 226 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 5 205 5.7E-45 T 12-10-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like MIM_c12530 92dfb714b122574c3155fedcc37254dd 132 SUPERFAMILY SSF50249 11 120 1.71E-29 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c12530 92dfb714b122574c3155fedcc37254dd 132 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 19 53 1.1E-10 T 12-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal MIM_c12530 92dfb714b122574c3155fedcc37254dd 132 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 54 114 5.8E-16 T 12-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal MIM_c37520 2c61552c6355f492f235d14312529a93 336 PIRSF PIRSF017082 1 335 8.7E-75 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c37520 2c61552c6355f492f235d14312529a93 336 Gene3D G3DSA:3.40.190.10 138 260 6.8E-100 T 12-10-2018 MIM_c37520 2c61552c6355f492f235d14312529a93 336 Gene3D G3DSA:3.40.190.150 42 325 6.8E-100 T 12-10-2018 MIM_c37520 2c61552c6355f492f235d14312529a93 336 SUPERFAMILY SSF53850 131 297 2.08E-13 T 12-10-2018 MIM_c37520 2c61552c6355f492f235d14312529a93 336 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 61 329 1.5E-73 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c20040 d250c8fb6a25a669be93909ab5eb1879 449 Gene3D G3DSA:3.90.1300.10 7 435 7.2E-93 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MIM_c20040 d250c8fb6a25a669be93909ab5eb1879 449 SUPERFAMILY SSF75304 23 442 5.76E-93 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MIM_c20040 d250c8fb6a25a669be93909ab5eb1879 449 Pfam PF01425 Amidase 52 424 2.9E-66 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MIM_c39480 9318bffc04f611c340f8eb6baee3aedc 512 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 19 439 3.2E-129 T 12-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane MIM_c23080 965412c8bbadf2b39de8409cbae46dc4 263 Gene3D G3DSA:3.30.428.30 38 259 9.7E-75 T 12-10-2018 IPR038433 CDP-diacylglycerol pyrophosphatase superfamily KEGG: 00564+3.6.1.26 MIM_c23080 965412c8bbadf2b39de8409cbae46dc4 263 SUPERFAMILY SSF54197 44 256 6.38E-67 T 12-10-2018 IPR036265 HIT-like superfamily MIM_c23080 965412c8bbadf2b39de8409cbae46dc4 263 Pfam PF02611 CDP-diacylglycerol pyrophosphatase 44 257 1.8E-76 T 12-10-2018 IPR003763 CDP-diacylglycerol pyrophosphatase GO:0008654|GO:0008715|GO:0016020 KEGG: 00564+3.6.1.26 MIM_c23080 965412c8bbadf2b39de8409cbae46dc4 263 PIRSF PIRSF001273 13 262 4.0E-69 T 12-10-2018 IPR003763 CDP-diacylglycerol pyrophosphatase GO:0008654|GO:0008715|GO:0016020 KEGG: 00564+3.6.1.26 MIM_c10180 12982a7c21d63be65c2d17cf5cc21034 335 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 32 313 6.3E-86 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 MIM_c10180 12982a7c21d63be65c2d17cf5cc21034 335 Gene3D G3DSA:3.40.190.170 24 320 6.8E-109 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily MIM_c10180 12982a7c21d63be65c2d17cf5cc21034 335 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 32 286 1.5E-72 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 MIM_c10180 12982a7c21d63be65c2d17cf5cc21034 335 PIRSF PIRSF006470 1 326 1.8E-96 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 MIM_c12740 b6eae85d1e90e44083d896bdc3ccdfeb 412 Gene3D G3DSA:1.20.1250.20 6 411 3.2E-36 T 12-10-2018 MIM_c12740 b6eae85d1e90e44083d896bdc3ccdfeb 412 Pfam PF07690 Major Facilitator Superfamily 18 364 1.5E-28 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c12740 b6eae85d1e90e44083d896bdc3ccdfeb 412 SUPERFAMILY SSF103473 9 410 9.81E-44 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c37300 3eabf39fa2fd5cedff29b5ed81cffef4 142 SUPERFAMILY SSF54593 7 135 6.85E-18 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c37300 3eabf39fa2fd5cedff29b5ed81cffef4 142 Gene3D G3DSA:3.30.720.120 4 67 6.7E-16 T 12-10-2018 MIM_c37300 3eabf39fa2fd5cedff29b5ed81cffef4 142 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 118 7.7E-6 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MIM_c37300 3eabf39fa2fd5cedff29b5ed81cffef4 142 Gene3D G3DSA:3.30.720.110 82 141 4.8E-12 T 12-10-2018 MIM_c38430 24c086cf46a7d7a24540495806a69fb4 798 Gene3D G3DSA:2.140.10.10 147 792 1.5E-138 T 12-10-2018 MIM_c38430 24c086cf46a7d7a24540495806a69fb4 798 SUPERFAMILY SSF50998 167 784 1.83E-130 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MIM_c38430 24c086cf46a7d7a24540495806a69fb4 798 Pfam PF01011 PQQ enzyme repeat 728 761 1.7E-6 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat MIM_c38430 24c086cf46a7d7a24540495806a69fb4 798 Pfam PF01011 PQQ enzyme repeat 226 255 2.6E-6 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat MIM_c38430 24c086cf46a7d7a24540495806a69fb4 798 SMART SM00564 406 456 490.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c38430 24c086cf46a7d7a24540495806a69fb4 798 SMART SM00564 278 310 490.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c38430 24c086cf46a7d7a24540495806a69fb4 798 SMART SM00564 220 251 3.6E-5 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c38430 24c086cf46a7d7a24540495806a69fb4 798 SMART SM00564 337 378 12.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c38430 24c086cf46a7d7a24540495806a69fb4 798 SMART SM00564 718 751 2.8E-7 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c38430 24c086cf46a7d7a24540495806a69fb4 798 TIGRFAM TIGR03074 PQQ_membr_DH: membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family 16 796 7.7E-280 T 12-10-2018 IPR017511 PQQ-dependent membrane bound dehydrogenase GO:0016021|GO:0016614|GO:0048038|GO:0055114 MIM_c09570 24e4787c41bd3d58b17c7130eb938b4a 104 Gene3D G3DSA:3.40.1260.10 7 104 2.1E-10 T 12-10-2018 IPR027396 DsrEFH-like MIM_c09570 24e4787c41bd3d58b17c7130eb938b4a 104 SUPERFAMILY SSF75169 9 103 2.47E-11 T 12-10-2018 IPR027396 DsrEFH-like MIM_c20660 47c67f4070acbe42f6fe382e314ced0a 291 Gene3D G3DSA:1.10.1040.10 189 289 3.7E-27 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MIM_c20660 47c67f4070acbe42f6fe382e314ced0a 291 Gene3D G3DSA:3.40.50.720 2 188 9.9E-68 T 12-10-2018 MIM_c20660 47c67f4070acbe42f6fe382e314ced0a 291 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 6 184 1.3E-59 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MIM_c20660 47c67f4070acbe42f6fe382e314ced0a 291 SUPERFAMILY SSF48179 186 289 1.02E-26 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c20660 47c67f4070acbe42f6fe382e314ced0a 291 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 187 283 1.1E-25 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MIM_c20660 47c67f4070acbe42f6fe382e314ced0a 291 SUPERFAMILY SSF51735 1 186 1.69E-54 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c20660 47c67f4070acbe42f6fe382e314ced0a 291 PIRSF PIRSF000105 2 289 3.4E-86 T 12-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 MIM_c06400 12bfa277ff4f4e0391e4c09e50fc6f91 774 Pfam PF02538 Hydantoinase B/oxoprolinase 50 629 7.2E-126 T 12-10-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 MIM_c29140 f06a2917427e1aa34c12baa924fefd3d 72 Gene3D G3DSA:2.60.200.60 2 62 7.7E-11 T 12-10-2018 MIM_c28500 4a38f5a687da4e42df99ffb3b3a60ce6 207 Gene3D G3DSA:3.90.550.10 12 204 4.4E-48 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MIM_c28500 4a38f5a687da4e42df99ffb3b3a60ce6 207 SUPERFAMILY SSF53448 15 197 5.18E-32 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MIM_c28500 4a38f5a687da4e42df99ffb3b3a60ce6 207 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 13 200 26.3 T 12-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 MIM_c28500 4a38f5a687da4e42df99ffb3b3a60ce6 207 TIGRFAM TIGR02665 molyb_mobA: molybdenum cofactor guanylyltransferase 16 198 6.9E-58 T 12-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 MIM_c28500 4a38f5a687da4e42df99ffb3b3a60ce6 207 Pfam PF12804 MobA-like NTP transferase domain 17 169 3.4E-29 T 12-10-2018 IPR025877 MobA-like NTP transferase MIM_c27870 6fb2cd6b30381cae1d943e748f00bd72 291 SUPERFAMILY SSF53955 151 270 2.92E-22 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily MIM_c27870 6fb2cd6b30381cae1d943e748f00bd72 291 Gene3D G3DSA:1.10.530.10 146 278 1.1E-18 T 12-10-2018 MIM_c27870 6fb2cd6b30381cae1d943e748f00bd72 291 Pfam PF01464 Transglycosylase SLT domain 167 248 3.3E-14 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 MIM_c07640 b04ae66283d54b384e517f92bf1a538a 356 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 277 351 2.9E-16 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c07640 b04ae66283d54b384e517f92bf1a538a 356 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 91 165 5.6E-15 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c07640 b04ae66283d54b384e517f92bf1a538a 356 Gene3D G3DSA:1.10.760.10 268 356 4.0E-32 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c07640 b04ae66283d54b384e517f92bf1a538a 356 Gene3D G3DSA:1.10.760.10 89 168 2.5E-28 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c07640 b04ae66283d54b384e517f92bf1a538a 356 SUPERFAMILY SSF46626 278 353 4.87E-17 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c07640 b04ae66283d54b384e517f92bf1a538a 356 SUPERFAMILY SSF46626 91 167 1.33E-15 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c07640 b04ae66283d54b384e517f92bf1a538a 356 PRINTS PR00607 Class IE cytochrome C signature 341 352 3.4E-13 T 12-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 MIM_c07640 b04ae66283d54b384e517f92bf1a538a 356 PRINTS PR00607 Class IE cytochrome C signature 299 309 3.4E-13 T 12-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 MIM_c07640 b04ae66283d54b384e517f92bf1a538a 356 PRINTS PR00607 Class IE cytochrome C signature 327 339 3.4E-13 T 12-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 MIM_c07640 b04ae66283d54b384e517f92bf1a538a 356 PRINTS PR00607 Class IE cytochrome C signature 288 299 3.4E-13 T 12-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 MIM_c34020 2ca02822cf82d1cecab032c2224af771 189 Gene3D G3DSA:1.10.357.10 1 179 4.6E-44 T 12-10-2018 MIM_c34020 2ca02822cf82d1cecab032c2224af771 189 SUPERFAMILY SSF46689 2 74 1.3E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c34020 2ca02822cf82d1cecab032c2224af771 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 7.8E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c34020 2ca02822cf82d1cecab032c2224af771 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 4.4E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c34020 2ca02822cf82d1cecab032c2224af771 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 4.4E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c34020 2ca02822cf82d1cecab032c2224af771 189 SUPERFAMILY SSF48498 79 154 4.08E-5 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MIM_c40890 379ce9910ea0cc4dacdecd277b480ece 370 Gene3D G3DSA:3.60.60.10 19 354 4.1E-89 T 12-10-2018 MIM_c40890 379ce9910ea0cc4dacdecd277b480ece 370 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 134 353 3.2E-17 T 12-10-2018 IPR005079 Peptidase C45 MIM_c40890 379ce9910ea0cc4dacdecd277b480ece 370 Gene3D G3DSA:1.10.10.2120 33 105 4.1E-89 T 12-10-2018 MIM_c36540 42a691797fbfb5439cd1348a50e4d92e 324 PIRSF PIRSF017082 1 324 4.1E-55 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c36540 42a691797fbfb5439cd1348a50e4d92e 324 Gene3D G3DSA:3.40.190.10 125 249 4.0E-74 T 12-10-2018 MIM_c36540 42a691797fbfb5439cd1348a50e4d92e 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 320 4.4E-51 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c36540 42a691797fbfb5439cd1348a50e4d92e 324 Gene3D G3DSA:3.40.190.150 31 314 4.0E-74 T 12-10-2018 MIM_c34890 edec84ad5a20aa5044b5454740b29fd3 270 SUPERFAMILY SSF51735 6 265 3.55E-64 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c34890 edec84ad5a20aa5044b5454740b29fd3 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 230 250 1.9E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c34890 edec84ad5a20aa5044b5454740b29fd3 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.9E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c34890 edec84ad5a20aa5044b5454740b29fd3 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.9E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c34890 edec84ad5a20aa5044b5454740b29fd3 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 1.9E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c34890 edec84ad5a20aa5044b5454740b29fd3 270 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 265 4.2E-41 T 12-10-2018 MIM_c34890 edec84ad5a20aa5044b5454740b29fd3 270 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 196 0.0092 T 12-10-2018 MIM_c34890 edec84ad5a20aa5044b5454740b29fd3 270 Gene3D G3DSA:3.40.50.720 1 267 1.1E-65 T 12-10-2018 MIM_c09950 63cb2ed3d1dce5c661833ba384bd2f1f 177 Gene3D G3DSA:2.60.40.200 23 177 1.4E-52 T 12-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MIM_c09950 63cb2ed3d1dce5c661833ba384bd2f1f 177 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 36 176 7.8E-30 T 12-10-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MIM_c09950 63cb2ed3d1dce5c661833ba384bd2f1f 177 SUPERFAMILY SSF49329 27 177 3.27E-47 T 12-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MIM_c09950 63cb2ed3d1dce5c661833ba384bd2f1f 177 ProSitePatterns PS00332 Copper/Zinc superoxide dismutase signature 2. 165 176 - T 12-10-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MIM_c11670 b0cfd377a90fa6a7fb461273816b862b 142 Pfam PF08897 Domain of unknown function (DUF1841) 5 136 6.9E-58 T 12-10-2018 IPR014993 Protein of unknown function DUF1841 MIM_c37920 280173b69b62e9c8759ced5ade171319 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 250 9.8E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c37920 280173b69b62e9c8759ced5ade171319 263 SUPERFAMILY SSF161098 6 252 1.83E-57 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c37920 280173b69b62e9c8759ced5ade171319 263 Gene3D G3DSA:1.10.3720.10 6 260 8.1E-54 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c27520 2935365850601e99a863b46842ad1e36 210 SUPERFAMILY SSF47413 25 90 1.04E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c27520 2935365850601e99a863b46842ad1e36 210 SUPERFAMILY SSF51182 70 207 7.19E-12 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c27520 2935365850601e99a863b46842ad1e36 210 Gene3D G3DSA:2.60.120.10 116 210 2.0E-10 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c27520 2935365850601e99a863b46842ad1e36 210 Pfam PF01381 Helix-turn-helix 31 85 9.4E-15 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c27520 2935365850601e99a863b46842ad1e36 210 SMART SM00530 30 85 7.8E-16 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MIM_c27520 2935365850601e99a863b46842ad1e36 210 Gene3D G3DSA:1.10.260.40 26 109 4.2E-19 T 12-10-2018 MIM_c29390 8cf19a9bfa8b4d0ca0d080cf415a0e9d 316 Pfam PF00294 pfkB family carbohydrate kinase 41 294 2.9E-39 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB MIM_c29390 8cf19a9bfa8b4d0ca0d080cf415a0e9d 316 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 49 73 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MIM_c29390 8cf19a9bfa8b4d0ca0d080cf415a0e9d 316 Gene3D G3DSA:3.40.1190.20 3 315 4.6E-99 T 12-10-2018 IPR029056 Ribokinase-like MIM_c29390 8cf19a9bfa8b4d0ca0d080cf415a0e9d 316 SUPERFAMILY SSF53613 2 298 2.49E-62 T 12-10-2018 IPR029056 Ribokinase-like MIM_c35140 c1a24152603e389d37852a5c8125736f 341 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 31 213 7.6E-34 T 12-10-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal MIM_c35140 c1a24152603e389d37852a5c8125736f 341 Gene3D G3DSA:1.10.10.60 244 341 1.0E-21 T 12-10-2018 MIM_c35140 c1a24152603e389d37852a5c8125736f 341 SUPERFAMILY SSF46689 293 341 1.12E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c35140 c1a24152603e389d37852a5c8125736f 341 SMART SM00342 258 340 5.4E-22 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c35140 c1a24152603e389d37852a5c8125736f 341 Pfam PF12833 Helix-turn-helix domain 265 341 5.6E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MIM_c09560 ab2f0978ab5dd7851cd12700870d1e52 334 Pfam PF00107 Zinc-binding dehydrogenase 180 292 3.2E-8 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MIM_c09560 ab2f0978ab5dd7851cd12700870d1e52 334 SMART SM00829 7 331 0.0015 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MIM_c09560 ab2f0978ab5dd7851cd12700870d1e52 334 Gene3D G3DSA:3.40.50.720 147 278 3.8E-77 T 12-10-2018 MIM_c09560 ab2f0978ab5dd7851cd12700870d1e52 334 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 129 2.5E-33 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MIM_c09560 ab2f0978ab5dd7851cd12700870d1e52 334 Gene3D G3DSA:3.90.180.10 14 298 3.8E-77 T 12-10-2018 MIM_c09560 ab2f0978ab5dd7851cd12700870d1e52 334 SUPERFAMILY SSF51735 137 297 1.17E-22 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c09560 ab2f0978ab5dd7851cd12700870d1e52 334 SUPERFAMILY SSF50129 1 173 2.74E-50 T 12-10-2018 IPR011032 GroES-like superfamily MIM_c34310 18676043c88fb3c4e7517ca5f10e6fe4 302 Pfam PF01844 HNH endonuclease 227 281 3.4E-8 T 12-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 MIM_c34310 18676043c88fb3c4e7517ca5f10e6fe4 302 SMART SM00507 215 277 0.006 T 12-10-2018 IPR003615 HNH nuclease MIM_c09530 069bfd7304eebe6af5c465f89530c09e 437 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 1 420 32.019 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MIM_c09530 069bfd7304eebe6af5c465f89530c09e 437 PRINTS PR00083 Histidinol dehydrogenase signature 191 216 2.2E-61 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MIM_c09530 069bfd7304eebe6af5c465f89530c09e 437 PRINTS PR00083 Histidinol dehydrogenase signature 354 372 2.2E-61 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MIM_c09530 069bfd7304eebe6af5c465f89530c09e 437 PRINTS PR00083 Histidinol dehydrogenase signature 242 261 2.2E-61 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MIM_c09530 069bfd7304eebe6af5c465f89530c09e 437 PRINTS PR00083 Histidinol dehydrogenase signature 161 187 2.2E-61 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MIM_c09530 069bfd7304eebe6af5c465f89530c09e 437 PRINTS PR00083 Histidinol dehydrogenase signature 220 241 2.2E-61 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MIM_c09530 069bfd7304eebe6af5c465f89530c09e 437 PRINTS PR00083 Histidinol dehydrogenase signature 98 125 2.2E-61 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MIM_c09530 069bfd7304eebe6af5c465f89530c09e 437 PRINTS PR00083 Histidinol dehydrogenase signature 313 338 2.2E-61 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MIM_c09530 069bfd7304eebe6af5c465f89530c09e 437 PRINTS PR00083 Histidinol dehydrogenase signature 24 48 2.2E-61 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MIM_c09530 069bfd7304eebe6af5c465f89530c09e 437 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 220 252 - T 12-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 MIM_c09530 069bfd7304eebe6af5c465f89530c09e 437 Gene3D G3DSA:3.40.50.1980 23 222 5.9E-94 T 12-10-2018 MIM_c09530 069bfd7304eebe6af5c465f89530c09e 437 SUPERFAMILY SSF53720 17 420 6.47E-63 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MIM_c09530 069bfd7304eebe6af5c465f89530c09e 437 Gene3D G3DSA:3.40.50.1980 224 342 5.9E-94 T 12-10-2018 MIM_c09530 069bfd7304eebe6af5c465f89530c09e 437 Pfam PF00815 Histidinol dehydrogenase 13 419 4.7E-132 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MIM_c09530 069bfd7304eebe6af5c465f89530c09e 437 PIRSF PIRSF000099 2 423 1.6E-117 T 12-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MIM_c09530 069bfd7304eebe6af5c465f89530c09e 437 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 24 419 6.0E-131 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MIM_c20640 df6ba16d37c117677d58b0c93d3d8be1 378 SUPERFAMILY SSF89796 1 371 2.22E-108 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c20640 df6ba16d37c117677d58b0c93d3d8be1 378 Gene3D G3DSA:3.40.50.10540 4 326 3.1E-103 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily MIM_c20640 df6ba16d37c117677d58b0c93d3d8be1 378 Pfam PF02515 CoA-transferase family III 5 364 1.5E-95 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 MIM_c20640 df6ba16d37c117677d58b0c93d3d8be1 378 Gene3D G3DSA:3.30.1540.10 225 308 3.1E-103 T 12-10-2018 MIM_c39290 d998a49a843b68e1a149b672465b70b7 326 Pfam PF02653 Branched-chain amino acid transport system / permease component 28 302 6.1E-35 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c25390 077748c6dfbb3f032c9ea4ed31e4d7ab 286 Gene3D G3DSA:3.20.20.150 14 273 1.4E-36 T 12-10-2018 MIM_c25390 077748c6dfbb3f032c9ea4ed31e4d7ab 286 Pfam PF01261 Xylose isomerase-like TIM barrel 33 230 9.4E-14 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MIM_c25390 077748c6dfbb3f032c9ea4ed31e4d7ab 286 SUPERFAMILY SSF51658 13 265 3.73E-31 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily MIM_c12760 fc65799b4fac0594e90fc32a69096e8c 339 SUPERFAMILY SSF51735 125 308 4.92E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c12760 fc65799b4fac0594e90fc32a69096e8c 339 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 132 307 5.3E-45 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MIM_c12760 fc65799b4fac0594e90fc32a69096e8c 339 Gene3D G3DSA:3.40.50.720 81 334 1.4E-71 T 12-10-2018 MIM_c12760 fc65799b4fac0594e90fc32a69096e8c 339 Gene3D G3DSA:3.40.50.720 124 314 1.4E-71 T 12-10-2018 MIM_c12760 fc65799b4fac0594e90fc32a69096e8c 339 SUPERFAMILY SSF52283 83 142 7.05E-6 T 12-10-2018 MIM_c20580 38ec6ada39cfb0171971baa3d9a1aee4 392 Gene3D G3DSA:3.40.47.10 4 389 4.2E-118 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c20580 38ec6ada39cfb0171971baa3d9a1aee4 392 SUPERFAMILY SSF53901 32 357 4.53E-29 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c20580 38ec6ada39cfb0171971baa3d9a1aee4 392 PIRSF PIRSF000429 6 387 1.0E-33 T 12-10-2018 IPR002155 Thiolase GO:0016747 MIM_c03140 562a0cf30c9fd4edfec332c5fc3e7352 520 Gene3D G3DSA:3.40.190.10 14 271 6.4E-61 T 12-10-2018 MIM_c03140 562a0cf30c9fd4edfec332c5fc3e7352 520 PIRSF PIRSF002741 6 513 2.1E-87 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MIM_c03140 562a0cf30c9fd4edfec332c5fc3e7352 520 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 65 433 2.2E-87 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain MIM_c03140 562a0cf30c9fd4edfec332c5fc3e7352 520 SUPERFAMILY SSF53850 22 502 1.77E-119 T 12-10-2018 MIM_c03140 562a0cf30c9fd4edfec332c5fc3e7352 520 Gene3D G3DSA:3.10.105.10 282 492 1.0E-54 T 12-10-2018 MIM_c30560 0171b2dc0a0f67d2e06c891525929f48 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 299 4.7E-25 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c30560 0171b2dc0a0f67d2e06c891525929f48 302 Gene3D G3DSA:1.10.3720.10 89 300 1.1E-20 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c30560 0171b2dc0a0f67d2e06c891525929f48 302 SUPERFAMILY SSF161098 94 284 6.67E-26 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c00250 ca8f19d1fe45e49606fe8f7ccb598f00 236 ProSitePatterns PS00211 ABC transporters family signature. 122 136 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c00250 ca8f19d1fe45e49606fe8f7ccb598f00 236 SMART SM00382 30 199 6.8E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c00250 ca8f19d1fe45e49606fe8f7ccb598f00 236 Pfam PF00005 ABC transporter 21 149 2.0E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c00250 ca8f19d1fe45e49606fe8f7ccb598f00 236 Gene3D G3DSA:3.40.50.300 1 229 4.2E-56 T 12-10-2018 MIM_c00250 ca8f19d1fe45e49606fe8f7ccb598f00 236 SUPERFAMILY SSF52540 6 217 3.59E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c15230 085be033cdb4a12f0d2ea182065ce748 252 Gene3D G3DSA:3.40.50.620 115 215 3.7E-8 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c15230 085be033cdb4a12f0d2ea182065ce748 252 Pfam PF02698 DUF218 domain 77 242 2.3E-31 T 12-10-2018 IPR003848 Domain of unknown function DUF218 MIM_c10040 d42f12a8854ab3fa6059881545fc47fa 249 Pfam PF03591 AzlC protein 16 155 1.7E-37 T 12-10-2018 IPR011606 Branched-chain amino acid transport, permease MIM_c23560 e2c023a8d351782621cd935c830523e7 127 Pfam PF04241 Protein of unknown function (DUF423) 21 107 5.6E-29 T 12-10-2018 IPR006696 Protein of unknown function DUF423 MIM_c00210 5f207b0d403f57e51b35a0f9adab3aa6 401 SUPERFAMILY SSF53383 9 394 1.53E-53 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c00210 5f207b0d403f57e51b35a0f9adab3aa6 401 Pfam PF00266 Aminotransferase class-V 23 386 2.1E-36 T 12-10-2018 IPR000192 Aminotransferase class V domain MIM_c00210 5f207b0d403f57e51b35a0f9adab3aa6 401 Gene3D G3DSA:3.40.640.10 34 292 2.8E-61 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c00210 5f207b0d403f57e51b35a0f9adab3aa6 401 Gene3D G3DSA:3.90.1150.10 20 386 2.8E-61 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MIM_c05400 5569ca3f76a0062b56adbb043f4ef7b2 123 Gene3D G3DSA:2.60.40.1470 1 123 2.8E-50 T 12-10-2018 IPR036767 ApaG domain superfamily MIM_c05400 5569ca3f76a0062b56adbb043f4ef7b2 123 Pfam PF04379 ApaG domain 15 100 9.2E-34 T 12-10-2018 IPR007474 ApaG domain MIM_c05400 5569ca3f76a0062b56adbb043f4ef7b2 123 Hamap MF_00791 Protein ApaG [apaG]. 1 123 32.069 T 12-10-2018 IPR023065 Uncharacterised protein family ApaG MIM_c05400 5569ca3f76a0062b56adbb043f4ef7b2 123 SUPERFAMILY SSF110069 3 123 3.79E-47 T 12-10-2018 IPR036767 ApaG domain superfamily MIM_c36200 3b29e3386d4ca9378adf9dcbe4dee6ba 301 Gene3D G3DSA:1.10.10.10 2 91 1.6E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c36200 3b29e3386d4ca9378adf9dcbe4dee6ba 301 SUPERFAMILY SSF46785 3 83 2.63E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c36200 3b29e3386d4ca9378adf9dcbe4dee6ba 301 Gene3D G3DSA:3.40.190.10 165 266 2.2E-54 T 12-10-2018 MIM_c36200 3b29e3386d4ca9378adf9dcbe4dee6ba 301 Gene3D G3DSA:3.40.190.10 92 292 2.2E-54 T 12-10-2018 MIM_c36200 3b29e3386d4ca9378adf9dcbe4dee6ba 301 Pfam PF03466 LysR substrate binding domain 88 295 6.8E-35 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c36200 3b29e3386d4ca9378adf9dcbe4dee6ba 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.9E-14 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c36200 3b29e3386d4ca9378adf9dcbe4dee6ba 301 SUPERFAMILY SSF53850 89 298 4.34E-36 T 12-10-2018 MIM_c35640 609ff008631421f1e240e6a27c17fa2e 242 Gene3D G3DSA:3.40.50.300 3 229 5.9E-56 T 12-10-2018 MIM_c35640 609ff008631421f1e240e6a27c17fa2e 242 SMART SM00382 31 203 2.0E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c35640 609ff008631421f1e240e6a27c17fa2e 242 ProSitePatterns PS00211 ABC transporters family signature. 126 140 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c35640 609ff008631421f1e240e6a27c17fa2e 242 Pfam PF00005 ABC transporter 22 153 1.1E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c35640 609ff008631421f1e240e6a27c17fa2e 242 SUPERFAMILY SSF52540 17 214 1.73E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c02930 cce6b451187a6eade160e1c422933362 548 Pfam PF03929 PepSY-associated TM region 27 484 4.8E-81 T 12-10-2018 IPR005625 PepSY-associated TM protein MIM_c37000 eb09d513ae9737002efa114dba1e5b3e 346 Gene3D G3DSA:3.40.50.620 6 263 1.1E-44 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c37000 eb09d513ae9737002efa114dba1e5b3e 346 SUPERFAMILY SSF52402 21 238 7.98E-53 T 12-10-2018 MIM_c37000 eb09d513ae9737002efa114dba1e5b3e 346 Hamap MF_01850 tRNA-cytidine(32) 2-sulfurtransferase [ttcA]. 13 275 55.865 T 12-10-2018 IPR012089 tRNA-cytidine(32) 2-sulfurtransferase GO:0008033 MIM_c37000 eb09d513ae9737002efa114dba1e5b3e 346 Pfam PF01171 PP-loop family 45 208 8.0E-14 T 12-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 MIM_c41010 9e2da7ba0d2d59ce9305aa6b1c035fe1 408 Pfam PF12698 ABC-2 family transporter protein 63 399 7.4E-47 T 12-10-2018 MIM_c11860 de88845196be1ae513e84b76d5e1e32e 729 Pfam PF13515 Fusaric acid resistance protein-like 427 548 3.9E-16 T 12-10-2018 MIM_c11860 de88845196be1ae513e84b76d5e1e32e 729 Pfam PF12805 FUSC-like inner membrane protein yccS 72 347 2.1E-58 T 12-10-2018 IPR032692 Integral membrane protein YccS, N-terminal MIM_c14620 e928de4c9ef6e35330f1afb7c771cdf2 173 Gene3D G3DSA:2.160.10.10 1 172 9.5E-58 T 12-10-2018 MIM_c14620 e928de4c9ef6e35330f1afb7c771cdf2 173 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 122 9.2E-10 T 12-10-2018 IPR001451 Hexapeptide repeat MIM_c14620 e928de4c9ef6e35330f1afb7c771cdf2 173 SUPERFAMILY SSF51161 4 169 1.44E-42 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily MIM_c40200 7120339d20aa639f5f05e38dbf6621d9 151 SUPERFAMILY SSF54593 9 134 3.09E-21 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c40200 7120339d20aa639f5f05e38dbf6621d9 151 Gene3D G3DSA:3.10.180.10 2 145 1.6E-53 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c27200 17de7431126817874df1d84690200094 156 Pfam PF16155 Domain of unknown function (DUF4863) 8 151 6.6E-61 T 12-10-2018 IPR032345 Protein of unknown function DUF4863 MIM_c33630 56be4d5da66e0a3e1b00a447e7a4a69c 355 TIGRFAM TIGR04267 mod_HExxH: HEXXH motif domain 153 276 5.5E-12 T 12-10-2018 IPR026337 HEXXH motif domain MIM_c25850 1ef7f03381ba4c50c20a0b2df552b2b7 425 SUPERFAMILY SSF103473 226 412 2.35E-17 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c25850 1ef7f03381ba4c50c20a0b2df552b2b7 425 Gene3D G3DSA:1.20.1250.20 236 415 7.9E-14 T 12-10-2018 MIM_c25850 1ef7f03381ba4c50c20a0b2df552b2b7 425 Pfam PF07690 Major Facilitator Superfamily 243 409 1.5E-12 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c25850 1ef7f03381ba4c50c20a0b2df552b2b7 425 Pfam PF07690 Major Facilitator Superfamily 8 165 3.3E-8 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c25850 1ef7f03381ba4c50c20a0b2df552b2b7 425 Gene3D G3DSA:1.20.1250.20 5 180 5.8E-9 T 12-10-2018 MIM_c25850 1ef7f03381ba4c50c20a0b2df552b2b7 425 SUPERFAMILY SSF103473 7 178 2.62E-13 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c08290 79406ad4db549590e9f2a15e78772b35 255 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 208 5.8E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c08290 79406ad4db549590e9f2a15e78772b35 255 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 111 2.3E-30 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c08290 79406ad4db549590e9f2a15e78772b35 255 Gene3D G3DSA:1.10.3720.10 3 217 1.9E-50 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c08290 79406ad4db549590e9f2a15e78772b35 255 SUPERFAMILY SSF161098 14 208 1.83E-42 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c39210 413adacf0f1318aaf09bf7d33073e7b3 226 SMART SM00862 146 219 2.5E-19 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MIM_c39210 413adacf0f1318aaf09bf7d33073e7b3 226 Gene3D G3DSA:1.10.10.10 127 225 5.0E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c39210 413adacf0f1318aaf09bf7d33073e7b3 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 219 5.2E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MIM_c39210 413adacf0f1318aaf09bf7d33073e7b3 226 Pfam PF00072 Response regulator receiver domain 3 113 7.6E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c39210 413adacf0f1318aaf09bf7d33073e7b3 226 Gene3D G3DSA:3.40.50.2300 1 126 2.4E-31 T 12-10-2018 MIM_c39210 413adacf0f1318aaf09bf7d33073e7b3 226 SMART SM00448 1 113 1.3E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MIM_c39210 413adacf0f1318aaf09bf7d33073e7b3 226 SUPERFAMILY SSF52172 1 172 7.12E-36 T 12-10-2018 IPR011006 CheY-like superfamily MIM_c10070 def7ca7f5597f091be8b39d59a7333bb 75 SUPERFAMILY SSF54285 4 75 2.04E-12 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp MIM_c10070 def7ca7f5597f091be8b39d59a7333bb 75 Gene3D G3DSA:3.10.20.30 4 75 8.1E-15 T 12-10-2018 IPR012675 Beta-grasp domain superfamily MIM_c10070 def7ca7f5597f091be8b39d59a7333bb 75 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 6 75 4.4E-13 T 12-10-2018 IPR010035 ThiS, thiamine-biosynthesis MIM_c10070 def7ca7f5597f091be8b39d59a7333bb 75 Pfam PF02597 ThiS family 7 75 5.1E-13 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 MIM_c13740 82164c88d1ea1eba7404d4533c720d9b 229 Gene3D G3DSA:3.40.50.360 32 211 6.2E-49 T 12-10-2018 IPR029039 Flavoprotein-like superfamily MIM_c13740 82164c88d1ea1eba7404d4533c720d9b 229 SUPERFAMILY SSF52218 44 179 1.21E-20 T 12-10-2018 IPR029039 Flavoprotein-like superfamily MIM_c13740 82164c88d1ea1eba7404d4533c720d9b 229 Pfam PF12682 Flavodoxin 44 185 1.8E-19 T 12-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 MIM_c29510 a3979a60232640287e4e2e25b523067c 391 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 5 369 9.0E-84 T 12-10-2018 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 MIM_c29510 a3979a60232640287e4e2e25b523067c 391 Pfam PF03739 Predicted permease YjgP/YjgQ family 7 368 1.3E-57 T 12-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 MIM_c22820 e87df3ee59bb7778d47e49a7981247d5 302 Gene3D G3DSA:1.10.3660.10 193 298 6.1E-33 T 12-10-2018 MIM_c22820 e87df3ee59bb7778d47e49a7981247d5 302 SUPERFAMILY SSF51735 21 185 1.25E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c22820 e87df3ee59bb7778d47e49a7981247d5 302 SUPERFAMILY SSF48179 189 297 3.06E-31 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MIM_c22820 e87df3ee59bb7778d47e49a7981247d5 302 Pfam PF02153 Prephenate dehydrogenase 33 288 2.5E-71 T 12-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 MIM_c22820 e87df3ee59bb7778d47e49a7981247d5 302 Gene3D G3DSA:3.40.50.720 19 192 6.6E-54 T 12-10-2018 MIM_c27940 278409561da9f73c6c358f68b7349888 379 Pfam PF01702 Queuine tRNA-ribosyltransferase 130 370 1.7E-91 T 12-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MIM_c27940 278409561da9f73c6c358f68b7349888 379 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 373 54.4 T 12-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MIM_c27940 278409561da9f73c6c358f68b7349888 379 Gene3D G3DSA:3.20.20.105 1 376 3.9E-163 T 12-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MIM_c27940 278409561da9f73c6c358f68b7349888 379 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 6 372 5.7E-163 T 12-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MIM_c27940 278409561da9f73c6c358f68b7349888 379 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 372 1.2E-156 T 12-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MIM_c27940 278409561da9f73c6c358f68b7349888 379 SUPERFAMILY SSF51713 4 372 1.96E-152 T 12-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MIM_c32260 1ba34241db1739be16d069f14906c9a3 83 Pfam PF00037 4Fe-4S binding domain 5 25 7.7E-6 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MIM_c32260 1ba34241db1739be16d069f14906c9a3 83 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MIM_c32260 1ba34241db1739be16d069f14906c9a3 83 SUPERFAMILY SSF54862 5 76 1.38E-18 T 12-10-2018 MIM_c32260 1ba34241db1739be16d069f14906c9a3 83 Gene3D G3DSA:3.30.70.20 2 81 3.0E-31 T 12-10-2018 MIM_c33720 2ef5af412d08feea1415f61a6d5aaa87 327 PIRSF PIRSF034367 1 327 8.4E-198 T 12-10-2018 IPR015004 Protein of unknown function DUF1852 MIM_c33720 2ef5af412d08feea1415f61a6d5aaa87 327 Pfam PF08908 Domain of unknown function (DUF1852) 1 323 3.9E-188 T 12-10-2018 IPR015004 Protein of unknown function DUF1852 MIM_c11150 98b67d3ef4b2bbcea07056efd8e8af13 335 PIRSF PIRSF017082 1 333 1.2E-66 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c11150 98b67d3ef4b2bbcea07056efd8e8af13 335 Gene3D G3DSA:3.40.190.150 36 323 9.1E-89 T 12-10-2018 MIM_c11150 98b67d3ef4b2bbcea07056efd8e8af13 335 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 327 6.6E-62 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c11150 98b67d3ef4b2bbcea07056efd8e8af13 335 SUPERFAMILY SSF53850 127 298 1.49E-9 T 12-10-2018 MIM_c11150 98b67d3ef4b2bbcea07056efd8e8af13 335 Gene3D G3DSA:3.40.190.10 134 259 9.1E-89 T 12-10-2018 MIM_c30710 65f49a07b78ade2af77329e3376750fa 193 Pfam PF01613 Flavin reductase like domain 20 155 4.8E-16 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MIM_c30710 65f49a07b78ade2af77329e3376750fa 193 SMART SM00903 15 158 3.3E-14 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MIM_c30710 65f49a07b78ade2af77329e3376750fa 193 Gene3D G3DSA:2.30.110.10 1 191 1.1E-46 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MIM_c30710 65f49a07b78ade2af77329e3376750fa 193 SUPERFAMILY SSF50475 4 187 6.87E-37 T 12-10-2018 MIM_c23740 92b8b1ad12dfd761d443dc54b87e6423 144 SUPERFAMILY SSF102400 1 141 1.31E-30 T 12-10-2018 IPR036768 DNA polymerase III subunit chi superfamily MIM_c23740 92b8b1ad12dfd761d443dc54b87e6423 144 Pfam PF04364 DNA polymerase III chi subunit, HolC 2 136 2.5E-30 T 12-10-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 MIM_c23740 92b8b1ad12dfd761d443dc54b87e6423 144 Gene3D G3DSA:3.40.50.10110 5 141 1.8E-29 T 12-10-2018 IPR036768 DNA polymerase III subunit chi superfamily MIM_c03360 dde0697202d47b30fd5a5fe068d3b7bc 205 Gene3D G3DSA:1.20.1290.10 13 177 5.4E-31 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c03360 dde0697202d47b30fd5a5fe068d3b7bc 205 SUPERFAMILY SSF69118 1 175 1.58E-30 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c03360 dde0697202d47b30fd5a5fe068d3b7bc 205 Pfam PF02627 Carboxymuconolactone decarboxylase family 42 115 3.6E-5 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MIM_c14900 d876fdd8c9db73f9e589b18d0766bad8 161 PIRSF PIRSF000239 1 161 7.7E-29 T 12-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MIM_c14900 d876fdd8c9db73f9e589b18d0766bad8 161 Pfam PF00578 AhpC/TSA family 7 133 1.2E-32 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MIM_c14900 d876fdd8c9db73f9e589b18d0766bad8 161 SUPERFAMILY SSF52833 5 155 7.6E-47 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c14900 d876fdd8c9db73f9e589b18d0766bad8 161 Gene3D G3DSA:3.40.30.10 2 155 1.1E-44 T 12-10-2018 MIM_c05840 9accb05d7904143a771ffa2c10fd7466 178 SUPERFAMILY SSF54593 1 146 1.19E-35 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c05840 9accb05d7904143a771ffa2c10fd7466 178 Gene3D G3DSA:3.10.180.10 1 169 1.4E-34 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c05840 9accb05d7904143a771ffa2c10fd7466 178 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 134 6.0E-16 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MIM_c25090 aae8f68821cb3908cd5bd1220d1927e9 173 Gene3D G3DSA:3.40.630.30 1 173 1.6E-51 T 12-10-2018 MIM_c25090 aae8f68821cb3908cd5bd1220d1927e9 173 Pfam PF13420 Acetyltransferase (GNAT) domain 12 156 5.1E-14 T 12-10-2018 MIM_c25090 aae8f68821cb3908cd5bd1220d1927e9 173 SUPERFAMILY SSF55729 3 164 2.57E-29 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c05700 67f59acb348af29024a96011d4bf8201 328 Pfam PF04280 Tim44-like domain 203 321 2.8E-16 T 12-10-2018 IPR007379 Tim44-like domain MIM_c05700 67f59acb348af29024a96011d4bf8201 328 SUPERFAMILY SSF54427 199 324 2.1E-15 T 12-10-2018 IPR032710 NTF2-like domain superfamily MIM_c05700 67f59acb348af29024a96011d4bf8201 328 Gene3D G3DSA:3.10.450.240 203 323 4.4E-6 T 12-10-2018 MIM_c05700 67f59acb348af29024a96011d4bf8201 328 SMART SM00978 193 321 9.3E-35 T 12-10-2018 IPR007379 Tim44-like domain MIM_c21550 d6bbca98a9e0f50db4d1a23219188035 159 Pfam PF13463 Winged helix DNA-binding domain 56 113 3.5E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c21550 d6bbca98a9e0f50db4d1a23219188035 159 SUPERFAMILY SSF46785 14 154 3.06E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c21550 d6bbca98a9e0f50db4d1a23219188035 159 Gene3D G3DSA:1.10.10.10 1 155 5.6E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c21550 d6bbca98a9e0f50db4d1a23219188035 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 130 150 9.0E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c21550 d6bbca98a9e0f50db4d1a23219188035 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 100 116 9.0E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c21550 d6bbca98a9e0f50db4d1a23219188035 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 80 9.0E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c21550 d6bbca98a9e0f50db4d1a23219188035 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 96 9.0E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c21550 d6bbca98a9e0f50db4d1a23219188035 159 SMART SM00347 39 140 1.5E-16 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c05200 a031cc45dd65ba483ffe96036f3fc04f 111 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 1 105 3.7E-33 T 12-10-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV MIM_c00100 bfc9418b6f0ab40154f587e4e5e9774e 254 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 45 97 2.1E-7 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MIM_c00100 bfc9418b6f0ab40154f587e4e5e9774e 254 SUPERFAMILY SSF56003 112 252 3.93E-19 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 MIM_c00100 bfc9418b6f0ab40154f587e4e5e9774e 254 Gene3D G3DSA:3.30.365.10 40 117 1.1E-11 T 12-10-2018 MIM_c00100 bfc9418b6f0ab40154f587e4e5e9774e 254 Gene3D G3DSA:3.30.365.10 161 252 3.6E-10 T 12-10-2018 MIM_c00100 bfc9418b6f0ab40154f587e4e5e9774e 254 SUPERFAMILY SSF56003 43 97 4.06E-11 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 MIM_c25320 efbd9e0d09be1a13743200c8f9df5584 549 Gene3D G3DSA:1.20.210.10 88 537 8.9E-150 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c25320 efbd9e0d09be1a13743200c8f9df5584 549 SUPERFAMILY SSF81442 95 530 1.13E-86 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c25320 efbd9e0d09be1a13743200c8f9df5584 549 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 99 508 7.8E-75 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c35150 bec54ea1de664ab82ce8601411ff1d94 525 Gene3D G3DSA:1.20.1730.10 21 500 1.8E-68 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily MIM_c35150 bec54ea1de664ab82ce8601411ff1d94 525 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 424 444 - T 12-10-2018 IPR018212 Sodium/solute symporter, conserved site MIM_c35150 bec54ea1de664ab82ce8601411ff1d94 525 Pfam PF00474 Sodium:solute symporter family 34 442 8.3E-48 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MIM_c21530 86a2dced2f6f48e596dc93e4ec3f7d88 323 Pfam PF16220 Domain of unknown function (DUF4880) 16 58 5.5E-12 T 12-10-2018 IPR032623 FecR, N-terminal MIM_c21530 86a2dced2f6f48e596dc93e4ec3f7d88 323 Gene3D G3DSA:2.60.120.1440 105 240 2.2E-20 T 12-10-2018 MIM_c21530 86a2dced2f6f48e596dc93e4ec3f7d88 323 Pfam PF04773 FecR protein 115 210 9.3E-18 T 12-10-2018 IPR006860 FecR protein MIM_c21530 86a2dced2f6f48e596dc93e4ec3f7d88 323 PIRSF PIRSF018266 5 323 6.3E-91 T 12-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component MIM_c37470 50490f4b9559b0948e5453d9a173938f 231 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 55 222 3.2E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c37470 50490f4b9559b0948e5453d9a173938f 231 SUPERFAMILY SSF161098 22 211 7.46E-39 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c37470 50490f4b9559b0948e5453d9a173938f 231 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 24 116 2.3E-23 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c37470 50490f4b9559b0948e5453d9a173938f 231 Gene3D G3DSA:1.10.3720.10 21 225 6.7E-48 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c01130 ff5cb290f5c382163ca19abc2ece4257 409 Gene3D G3DSA:3.40.710.30 21 408 3.2E-122 T 12-10-2018 MIM_c01130 ff5cb290f5c382163ca19abc2ece4257 409 Pfam PF00144 Beta-lactamase 37 398 2.8E-66 T 12-10-2018 IPR001466 Beta-lactamase-related MIM_c01130 ff5cb290f5c382163ca19abc2ece4257 409 SUPERFAMILY SSF56601 26 394 5.41E-71 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MIM_c25030 3497fc1b23f2d87c4630dd6aaf5b657f 162 Pfam PF01575 MaoC like domain 22 123 1.5E-24 T 12-10-2018 IPR002539 MaoC-like dehydratase domain MIM_c25030 3497fc1b23f2d87c4630dd6aaf5b657f 162 SUPERFAMILY SSF54637 17 159 5.46E-35 T 12-10-2018 IPR029069 HotDog domain superfamily MIM_c25030 3497fc1b23f2d87c4630dd6aaf5b657f 162 Gene3D G3DSA:3.10.129.10 10 162 6.7E-45 T 12-10-2018 MIM_c21390 81a6b6078acb830ee9b1cffe94d9e4b0 214 Gene3D G3DSA:1.20.120.1490 69 192 1.2E-10 T 12-10-2018 MIM_c21390 81a6b6078acb830ee9b1cffe94d9e4b0 214 Pfam PF07813 LTXXQ motif family protein 70 165 1.8E-8 T 12-10-2018 IPR012899 LTXXQ motif family protein GO:0042597 MIM_c26990 0b26b1c6ab9fb6a83ffaafda91c01550 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 20 131 5.3E-34 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c26990 0b26b1c6ab9fb6a83ffaafda91c01550 397 Gene3D G3DSA:1.10.540.10 2 134 1.9E-41 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c26990 0b26b1c6ab9fb6a83ffaafda91c01550 397 SUPERFAMILY SSF47203 247 395 2.09E-42 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c26990 0b26b1c6ab9fb6a83ffaafda91c01550 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 244 389 5.3E-28 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MIM_c26990 0b26b1c6ab9fb6a83ffaafda91c01550 397 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 349 368 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MIM_c26990 0b26b1c6ab9fb6a83ffaafda91c01550 397 Gene3D G3DSA:2.40.110.10 135 243 8.2E-37 T 12-10-2018 MIM_c26990 0b26b1c6ab9fb6a83ffaafda91c01550 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 136 231 1.5E-20 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MIM_c26990 0b26b1c6ab9fb6a83ffaafda91c01550 397 SUPERFAMILY SSF56645 7 243 3.93E-76 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c26990 0b26b1c6ab9fb6a83ffaafda91c01550 397 Gene3D G3DSA:1.20.140.10 245 397 8.2E-42 T 12-10-2018 MIM_c11730 666e1a4ac9278b34bbd665081b10db20 322 Gene3D G3DSA:3.40.190.10 123 247 5.0E-112 T 12-10-2018 MIM_c11730 666e1a4ac9278b34bbd665081b10db20 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 316 2.4E-83 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c11730 666e1a4ac9278b34bbd665081b10db20 322 SUPERFAMILY SSF53850 108 278 7.24E-11 T 12-10-2018 MIM_c11730 666e1a4ac9278b34bbd665081b10db20 322 PIRSF PIRSF017082 2 322 3.6E-80 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c11730 666e1a4ac9278b34bbd665081b10db20 322 Gene3D G3DSA:3.40.190.150 25 312 5.0E-112 T 12-10-2018 MIM_c34550 c13cc70bd17c79ee6b3293d1e6839162 261 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 160 1.3E-18 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MIM_c34550 c13cc70bd17c79ee6b3293d1e6839162 261 SUPERFAMILY SSF51735 1 208 7.3E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c34550 c13cc70bd17c79ee6b3293d1e6839162 261 Gene3D G3DSA:3.40.50.720 1 225 6.1E-52 T 12-10-2018 MIM_c04360 8de01bbdd2374810ab15c53bce66f166 293 Pfam PF13714 Phosphoenolpyruvate phosphomutase 11 251 3.5E-49 T 12-10-2018 MIM_c04360 8de01bbdd2374810ab15c53bce66f166 293 SUPERFAMILY SSF51621 6 280 1.08E-83 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MIM_c04360 8de01bbdd2374810ab15c53bce66f166 293 Gene3D G3DSA:3.20.20.60 1 289 1.6E-97 T 12-10-2018 MIM_c41000 cf65021bcd1a564147ee55b8ca7b441e 371 PRINTS PR00164 ABC-2 type transport system membrane protein signature 314 333 8.9E-8 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MIM_c41000 cf65021bcd1a564147ee55b8ca7b441e 371 PRINTS PR00164 ABC-2 type transport system membrane protein signature 294 313 8.9E-8 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MIM_c41000 cf65021bcd1a564147ee55b8ca7b441e 371 PRINTS PR00164 ABC-2 type transport system membrane protein signature 257 281 8.9E-8 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MIM_c41000 cf65021bcd1a564147ee55b8ca7b441e 371 Pfam PF12698 ABC-2 family transporter protein 40 364 2.9E-41 T 12-10-2018 MIM_c34660 8ac1c115f2a0d30dd982f2d5ca21b8d4 434 Gene3D G3DSA:3.50.50.60 36 389 4.8E-50 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c34660 8ac1c115f2a0d30dd982f2d5ca21b8d4 434 Gene3D G3DSA:3.30.9.10 130 350 4.8E-50 T 12-10-2018 MIM_c34660 8ac1c115f2a0d30dd982f2d5ca21b8d4 434 Pfam PF01266 FAD dependent oxidoreductase 36 388 8.3E-37 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MIM_c34660 8ac1c115f2a0d30dd982f2d5ca21b8d4 434 SUPERFAMILY SSF51905 34 401 2.46E-33 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c14200 3d961142a1ab13e9d81e70eb50f43c13 311 Gene3D G3DSA:1.10.3720.10 68 308 3.2E-58 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c14200 3d961142a1ab13e9d81e70eb50f43c13 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 300 5.6E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c14200 3d961142a1ab13e9d81e70eb50f43c13 311 SUPERFAMILY SSF161098 71 296 3.92E-50 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c05560 dc38c12e4bcadee642ca6675fb797613 227 Gene3D G3DSA:2.60.450.10 37 192 1.6E-30 T 12-10-2018 MIM_c05560 dc38c12e4bcadee642ca6675fb797613 227 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 42 187 1.9E-26 T 12-10-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 MIM_c05560 dc38c12e4bcadee642ca6675fb797613 227 Hamap MF_01914 Lipopolysaccharide export system protein LptA [lptA]. 7 188 21.094 T 12-10-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 MIM_c05560 dc38c12e4bcadee642ca6675fb797613 227 Pfam PF03968 OstA-like protein 46 163 9.8E-21 T 12-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal MIM_c13360 909affac2070c8ef237348d0fc8ccdcb 363 SUPERFAMILY SSF52540 44 183 2.13E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c13360 909affac2070c8ef237348d0fc8ccdcb 363 Gene3D G3DSA:3.40.50.300 5 189 2.3E-20 T 12-10-2018 MIM_c13360 909affac2070c8ef237348d0fc8ccdcb 363 Pfam PF03969 AFG1-like ATPase 3 355 1.7E-129 T 12-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 MIM_c29950 20da2a556fad7a1eb12c8607dd280385 227 TIGRFAM TIGR02796 tolQ: protein TolQ 10 224 2.1E-85 T 12-10-2018 IPR014163 Tol-Pal system, TolQ GO:0016021|GO:0043213 MIM_c29950 20da2a556fad7a1eb12c8607dd280385 227 Hamap MF_02202 Tol-Pal system protein TolQ [tolQ]. 9 227 39.039 T 12-10-2018 IPR014163 Tol-Pal system, TolQ GO:0016021|GO:0043213 MIM_c29950 20da2a556fad7a1eb12c8607dd280385 227 Pfam PF01618 MotA/TolQ/ExbB proton channel family 81 212 3.9E-41 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel MIM_c23400 e2a8d129bcc4a935bbd49e7c635bca34 241 TIGRFAM TIGR00608 radc: DNA repair protein RadC 28 241 3.0E-61 T 12-10-2018 IPR001405 Uncharacterised protein family UPF0758 MIM_c23400 e2a8d129bcc4a935bbd49e7c635bca34 241 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 190 195 - T 12-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site MIM_c23400 e2a8d129bcc4a935bbd49e7c635bca34 241 Pfam PF04002 RadC-like JAB domain 122 239 2.8E-38 T 12-10-2018 IPR025657 RadC-like JAB domain MIM_c23400 e2a8d129bcc4a935bbd49e7c635bca34 241 Gene3D G3DSA:3.40.140.10 117 241 4.0E-37 T 12-10-2018 MIM_c35430 75c363c9429b01f6c836773a515a4f0e 274 SUPERFAMILY SSF55469 25 273 9.55E-62 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MIM_c35430 75c363c9429b01f6c836773a515a4f0e 274 PIRSF PIRSF005426 23 274 1.2E-83 T 12-10-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 MIM_c35430 75c363c9429b01f6c836773a515a4f0e 274 Gene3D G3DSA:3.40.109.10 24 274 4.2E-64 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MIM_c35430 75c363c9429b01f6c836773a515a4f0e 274 Pfam PF00881 Nitroreductase family 34 91 2.4E-11 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MIM_c35430 75c363c9429b01f6c836773a515a4f0e 274 Pfam PF00881 Nitroreductase family 132 187 3.9E-9 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MIM_c14660 c82b40ab4d149d3f1bb400c81635bd40 139 Pfam PF03653 Uncharacterised protein family (UPF0093) 2 139 1.4E-45 T 12-10-2018 IPR005265 Uncharacterised protein family UPF0093 MIM_c14660 c82b40ab4d149d3f1bb400c81635bd40 139 PIRSF PIRSF004638 1 139 7.2E-49 T 12-10-2018 IPR005265 Uncharacterised protein family UPF0093 MIM_c37080 6db9892f1ea1b9a23865ca6af5461920 235 SUPERFAMILY SSF51735 8 235 1.18E-55 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c37080 6db9892f1ea1b9a23865ca6af5461920 235 Gene3D G3DSA:3.40.50.720 1 235 4.5E-59 T 12-10-2018 MIM_c37080 6db9892f1ea1b9a23865ca6af5461920 235 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 195 1.5E-27 T 12-10-2018 MIM_c37080 6db9892f1ea1b9a23865ca6af5461920 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.7E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c37080 6db9892f1ea1b9a23865ca6af5461920 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.7E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c37080 6db9892f1ea1b9a23865ca6af5461920 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.7E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c37080 6db9892f1ea1b9a23865ca6af5461920 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.7E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MIM_c18390 8088d9a0f4beb856387057c97654021e 112 Pfam PF07769 psiF repeat 34 66 1.7E-17 T 12-10-2018 IPR011690 Phosphate-starvation-induced PsiF repeat MIM_c18390 8088d9a0f4beb856387057c97654021e 112 Pfam PF07769 psiF repeat 80 110 2.6E-16 T 12-10-2018 IPR011690 Phosphate-starvation-induced PsiF repeat MIM_c08470 7174c419cf112d339b393b6215c07373 234 Gene3D G3DSA:1.10.3720.10 6 228 1.7E-44 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c08470 7174c419cf112d339b393b6215c07373 234 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 53 227 1.1E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c08470 7174c419cf112d339b393b6215c07373 234 SUPERFAMILY SSF161098 19 213 1.2E-37 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c08470 7174c419cf112d339b393b6215c07373 234 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 18 122 9.6E-15 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c28080 83e844038d3da1bae6db43fa253d2131 247 Gene3D G3DSA:3.40.190.10 102 194 4.3E-25 T 12-10-2018 MIM_c28080 83e844038d3da1bae6db43fa253d2131 247 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 29 231 2.4E-21 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c28080 83e844038d3da1bae6db43fa253d2131 247 SMART SM00062 16 236 6.3E-24 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c28080 83e844038d3da1bae6db43fa253d2131 247 Gene3D G3DSA:3.40.190.10 14 226 4.3E-25 T 12-10-2018 MIM_c28080 83e844038d3da1bae6db43fa253d2131 247 SUPERFAMILY SSF53850 17 233 1.94E-32 T 12-10-2018 MIM_c15480 6bee9b44931dda4d6c95088eb25ac052 316 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 41 269 3.6E-45 T 12-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 MIM_c15480 6bee9b44931dda4d6c95088eb25ac052 316 SUPERFAMILY SSF52402 17 223 2.79E-61 T 12-10-2018 MIM_c15480 6bee9b44931dda4d6c95088eb25ac052 316 Gene3D G3DSA:3.40.50.620 18 226 9.0E-57 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MIM_c15480 6bee9b44931dda4d6c95088eb25ac052 316 PIRSF PIRSF002936 11 316 3.6E-133 T 12-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MIM_c35720 81d97dfe52849969ebacec2b76fa68ba 171 SUPERFAMILY SSF53254 1 149 2.36E-24 T 12-10-2018 IPR029033 Histidine phosphatase superfamily MIM_c35720 81d97dfe52849969ebacec2b76fa68ba 171 Gene3D G3DSA:3.40.50.1240 1 168 4.9E-37 T 12-10-2018 IPR029033 Histidine phosphatase superfamily MIM_c35720 81d97dfe52849969ebacec2b76fa68ba 171 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 83 7.5E-7 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MIM_c25840 000d32b95ae5f598e5338251f5d6785b 624 Gene3D G3DSA:1.10.274.90 2 148 1.2E-44 T 12-10-2018 MIM_c25840 000d32b95ae5f598e5338251f5d6785b 624 Pfam PF06276 Ferric iron reductase FhuF-like transporter 431 586 2.3E-31 T 12-10-2018 IPR022770 Ferric iron reductase FhuF domain MIM_c25840 000d32b95ae5f598e5338251f5d6785b 624 Gene3D G3DSA:1.10.510.40 398 606 6.2E-62 T 12-10-2018 MIM_c25840 000d32b95ae5f598e5338251f5d6785b 624 Pfam PF04183 IucA / IucC family 160 409 4.5E-71 T 12-10-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0019290 MIM_c16100 1f3d01e0d500a20b003e5fcd23bad946 261 Pfam PF01925 Sulfite exporter TauE/SafE 26 255 1.8E-27 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MIM_c33650 1e7714bf3f7427518eb4e2ee74223b3c 282 Pfam PF03756 A-factor biosynthesis hotdog domain 89 220 4.5E-16 T 12-10-2018 IPR005509 A-factor biosynthesis hotdog domain MIM_c34880 f70cd202d7bcb50d47f60cfc3cd04a2b 537 Gene3D G3DSA:3.10.105.10 285 505 1.8E-136 T 12-10-2018 MIM_c34880 f70cd202d7bcb50d47f60cfc3cd04a2b 537 Gene3D G3DSA:3.90.76.10 70 186 1.8E-136 T 12-10-2018 MIM_c34880 f70cd202d7bcb50d47f60cfc3cd04a2b 537 PIRSF PIRSF002741 1 537 1.4E-145 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MIM_c34880 f70cd202d7bcb50d47f60cfc3cd04a2b 537 SUPERFAMILY SSF53850 35 536 4.19E-139 T 12-10-2018 MIM_c34880 f70cd202d7bcb50d47f60cfc3cd04a2b 537 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 87 109 - T 12-10-2018 IPR023765 Solute-binding protein family 5, conserved site MIM_c34880 f70cd202d7bcb50d47f60cfc3cd04a2b 537 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 449 4.0E-98 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain MIM_c34880 f70cd202d7bcb50d47f60cfc3cd04a2b 537 Gene3D G3DSA:3.40.190.10 48 519 1.8E-136 T 12-10-2018 MIM_c15050 73e9b038b33ccf5a2c56851dde1c6013 840 Pfam PF02687 FtsX-like permease family 298 388 4.2E-8 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MIM_c05620 f66a4b3200534d09941cbd079dd3cd51 502 Gene3D G3DSA:3.40.1020.10 328 502 1.5E-74 T 12-10-2018 IPR038110 Threonine dehydratase, ACT-like domain superfamily KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 MIM_c05620 f66a4b3200534d09941cbd079dd3cd51 502 SUPERFAMILY SSF55021 409 502 1.99E-27 T 12-10-2018 MIM_c05620 f66a4b3200534d09941cbd079dd3cd51 502 SUPERFAMILY SSF53686 9 355 5.5E-101 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MIM_c05620 f66a4b3200534d09941cbd079dd3cd51 502 TIGRFAM TIGR01124 ilvA_2Cterm: threonine ammonia-lyase, biosynthetic 4 502 2.8E-248 T 12-10-2018 IPR005787 Threonine dehydratase, biosynthetic GO:0004794|GO:0009097 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 MIM_c05620 f66a4b3200534d09941cbd079dd3cd51 502 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 42 55 - T 12-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 MIM_c05620 f66a4b3200534d09941cbd079dd3cd51 502 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 420 502 1.8E-24 T 12-10-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 MIM_c05620 f66a4b3200534d09941cbd079dd3cd51 502 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 319 408 3.4E-24 T 12-10-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 MIM_c05620 f66a4b3200534d09941cbd079dd3cd51 502 Gene3D G3DSA:3.40.50.1100 50 146 1.6E-137 T 12-10-2018 MIM_c05620 f66a4b3200534d09941cbd079dd3cd51 502 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 306 1.3E-79 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MIM_c05620 f66a4b3200534d09941cbd079dd3cd51 502 Gene3D G3DSA:3.40.50.1100 14 317 1.6E-137 T 12-10-2018 MIM_c30890 a9fbd42e002ec42349f8a74e8e05e6f3 91 Gene3D G3DSA:3.30.70.1060 1 91 9.0E-38 T 12-10-2018 MIM_c30890 a9fbd42e002ec42349f8a74e8e05e6f3 91 ProDom PD006619 ISOMERASE MUCONOLACTONE DELTA-ISOMERASE HYDROCARBONS MIASE AROMATIC CATABOLISM METHYLMUCONOLACTONE DIRECT SEQUENCING 1 57 4.0E-19 T 12-10-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 MIM_c30890 a9fbd42e002ec42349f8a74e8e05e6f3 91 TIGRFAM TIGR03221 muco_delta: muconolactone delta-isomerase 2 91 5.8E-49 T 12-10-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 MIM_c30890 a9fbd42e002ec42349f8a74e8e05e6f3 91 Pfam PF02426 Muconolactone delta-isomerase 1 89 9.3E-44 T 12-10-2018 IPR026029 Muconolactone isomerase domain KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 MIM_c30890 a9fbd42e002ec42349f8a74e8e05e6f3 91 PIRSF PIRSF001486 1 91 3.9E-48 T 12-10-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 MIM_c30890 a9fbd42e002ec42349f8a74e8e05e6f3 91 SUPERFAMILY SSF54909 1 91 9.12E-41 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel MIM_c30330 8e0f1b81f280c61dfaa03e04bacce132 384 Pfam PF02735 Ku70/Ku80 beta-barrel domain 12 171 6.2E-30 T 12-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 MIM_c30330 8e0f1b81f280c61dfaa03e04bacce132 384 Gene3D G3DSA:2.40.290.10 5 179 2.8E-15 T 12-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily MIM_c30330 8e0f1b81f280c61dfaa03e04bacce132 384 SMART SM00559 53 184 2.8E-20 T 12-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 MIM_c30330 8e0f1b81f280c61dfaa03e04bacce132 384 SUPERFAMILY SSF100939 2 271 1.06E-45 T 12-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily MIM_c30330 8e0f1b81f280c61dfaa03e04bacce132 384 PIRSF PIRSF006493 299 378 4000.0 T 12-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type MIM_c30330 8e0f1b81f280c61dfaa03e04bacce132 384 PIRSF PIRSF006493 1 305 6.1E-82 T 12-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type MIM_c30330 8e0f1b81f280c61dfaa03e04bacce132 384 TIGRFAM TIGR02772 Ku_bact: Ku protein 2 268 2.2E-90 T 12-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type MIM_c30330 8e0f1b81f280c61dfaa03e04bacce132 384 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 2 266 29.788 T 12-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type MIM_c19730 499518ac8282115b4166f1a7847b5579 229 Gene3D G3DSA:3.50.30.100 2 197 9.0E-55 T 12-10-2018 MIM_c19730 499518ac8282115b4166f1a7847b5579 229 Pfam PF03737 Aldolase/RraA 27 173 9.6E-43 T 12-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MIM_c19730 499518ac8282115b4166f1a7847b5579 229 SUPERFAMILY SSF89562 23 184 5.49E-45 T 12-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily MIM_c06600 00b380e7f58a7fd345cc9d32618a2562 433 Pfam PF07399 Putative Na+/H+ antiporter 5 423 4.3E-186 T 12-10-2018 IPR009978 Putative Na+/H+ antiporter MIM_c23260 36c005729876601e58dc282aa76e95d3 354 Gene3D G3DSA:3.20.20.100 1 353 5.0E-113 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MIM_c23260 36c005729876601e58dc282aa76e95d3 354 SUPERFAMILY SSF51430 1 349 4.58E-94 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MIM_c23260 36c005729876601e58dc282aa76e95d3 354 Pfam PF00248 Aldo/keto reductase family 16 345 3.9E-69 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain MIM_c26850 cdfd31106fec02953ad5bd2717f91de4 341 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 40 333 2.4E-106 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 MIM_c26850 cdfd31106fec02953ad5bd2717f91de4 341 SUPERFAMILY SSF53659 12 337 3.64E-106 T 12-10-2018 MIM_c26850 cdfd31106fec02953ad5bd2717f91de4 341 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 13 336 2.1E-113 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 MIM_c26850 cdfd31106fec02953ad5bd2717f91de4 341 Gene3D G3DSA:3.40.718.10 3 338 1.2E-126 T 12-10-2018 MIM_c03100 d1381e42b2a84bad1a7dcb11a5d3e778 324 SUPERFAMILY SSF161098 90 305 3.66E-20 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c03100 d1381e42b2a84bad1a7dcb11a5d3e778 324 Gene3D G3DSA:1.10.3720.10 83 315 2.3E-25 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c03100 d1381e42b2a84bad1a7dcb11a5d3e778 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 319 1.2E-40 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c37600 4721f7a54db97eee8d45ad78fc0f06ab 332 Gene3D G3DSA:3.40.190.150 38 322 8.4E-98 T 12-10-2018 MIM_c37600 4721f7a54db97eee8d45ad78fc0f06ab 332 SUPERFAMILY SSF53850 121 284 1.49E-18 T 12-10-2018 MIM_c37600 4721f7a54db97eee8d45ad78fc0f06ab 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 58 327 4.5E-65 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c37600 4721f7a54db97eee8d45ad78fc0f06ab 332 Gene3D G3DSA:3.40.190.10 136 257 8.4E-98 T 12-10-2018 MIM_c37600 4721f7a54db97eee8d45ad78fc0f06ab 332 PIRSF PIRSF017082 1 331 1.9E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c36830 c2ece2e311faf437f022508f59489b76 125 PIRSF PIRSF029720 1 125 1.7E-46 T 12-10-2018 IPR014558 Uncharacterised conserved lipoprotein MIM_c36830 c2ece2e311faf437f022508f59489b76 125 Pfam PF03640 Secreted repeat of unknown function 82 124 2.9E-18 T 12-10-2018 IPR005297 Lipoprotein repeat MIM_c36830 c2ece2e311faf437f022508f59489b76 125 Pfam PF03640 Secreted repeat of unknown function 28 69 3.4E-16 T 12-10-2018 IPR005297 Lipoprotein repeat MIM_c04800 7c81ed7a1f8599e4cd3d7c1ec361c0b7 265 SUPERFAMILY SSF52540 33 243 5.95E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c04800 7c81ed7a1f8599e4cd3d7c1ec361c0b7 265 Pfam PF00005 ABC transporter 38 180 2.5E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c04800 7c81ed7a1f8599e4cd3d7c1ec361c0b7 265 Gene3D G3DSA:3.40.50.300 2 260 3.3E-66 T 12-10-2018 MIM_c04800 7c81ed7a1f8599e4cd3d7c1ec361c0b7 265 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c04800 7c81ed7a1f8599e4cd3d7c1ec361c0b7 265 SMART SM00382 47 227 1.5E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c32300 4a5fde54f22e46dee38a42e44d815d00 99 Pfam PF14384 BrnA antitoxin of type II toxin-antitoxin system 37 90 3.4E-17 T 12-10-2018 IPR025528 BrnA antitoxin of type II toxin-antitoxin system MIM_c38080 0f7e7b543c606bfce9ef1b5a86dd2a69 188 PIRSF PIRSF028301 6 183 6.2E-60 T 12-10-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 MIM_c38080 0f7e7b543c606bfce9ef1b5a86dd2a69 188 TIGRFAM TIGR03358 VI_chp_5: type VI secretion protein, VC_A0107 family 12 168 2.1E-55 T 12-10-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 MIM_c38080 0f7e7b543c606bfce9ef1b5a86dd2a69 188 Pfam PF05591 Type VI secretion system, VipA, VC_A0107 or Hcp2 16 165 1.8E-58 T 12-10-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 MIM_c17650 443d657a726ca866e77e142f06c93dac 334 Gene3D G3DSA:3.40.190.150 39 324 6.3E-99 T 12-10-2018 MIM_c17650 443d657a726ca866e77e142f06c93dac 334 Gene3D G3DSA:3.40.190.10 137 259 6.3E-99 T 12-10-2018 MIM_c17650 443d657a726ca866e77e142f06c93dac 334 PIRSF PIRSF017082 3 333 2.4E-73 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c17650 443d657a726ca866e77e142f06c93dac 334 SUPERFAMILY SSF53850 120 294 1.74E-10 T 12-10-2018 MIM_c17650 443d657a726ca866e77e142f06c93dac 334 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 59 326 1.0E-71 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c02320 d4964b9fa928fc6bdc049f8c5488577d 339 Pfam PF02625 XdhC and CoxI family 15 87 3.2E-21 T 12-10-2018 IPR003777 XdhC- CoxI MIM_c02320 d4964b9fa928fc6bdc049f8c5488577d 339 Gene3D G3DSA:3.40.50.720 169 318 1.3E-41 T 12-10-2018 MIM_c02320 d4964b9fa928fc6bdc049f8c5488577d 339 Pfam PF13478 XdhC Rossmann domain 170 312 1.9E-35 T 12-10-2018 IPR027051 XdhC Rossmann domain MIM_c35870 b2a7232c3781e279eef38283f9bacff0 325 Pfam PF06189 5'-nucleotidase 38 308 5.5E-108 T 12-10-2018 IPR010394 5-nucleotidase GO:0000166|GO:0000287|GO:0005737|GO:0008253|GO:0009117 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821|Reactome: R-HSA-74259 MIM_c35870 b2a7232c3781e279eef38283f9bacff0 325 SUPERFAMILY SSF56784 162 295 3.71E-5 T 12-10-2018 IPR036412 HAD-like superfamily MIM_c15770 bd9c0b98a7850f54dc3733e7858a797e 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 85 1.1E-26 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c15770 bd9c0b98a7850f54dc3733e7858a797e 88 SUPERFAMILY SSF46992 3 86 2.09E-27 T 12-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c15770 bd9c0b98a7850f54dc3733e7858a797e 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.003 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c15770 bd9c0b98a7850f54dc3733e7858a797e 88 Pfam PF01649 Ribosomal protein S20 2 83 1.3E-24 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c15770 bd9c0b98a7850f54dc3733e7858a797e 88 Gene3D G3DSA:1.20.58.110 1 87 1.1E-26 T 12-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c15770 bd9c0b98a7850f54dc3733e7858a797e 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 12 76 2.0E-17 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c38600 2444a8c506645b74e41cec66cd6f0ede 165 Gene3D G3DSA:2.40.50.140 1 121 8.4E-48 T 12-10-2018 MIM_c38600 2444a8c506645b74e41cec66cd6f0ede 165 SUPERFAMILY SSF50249 3 165 2.57E-62 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c38600 2444a8c506645b74e41cec66cd6f0ede 165 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 38.785 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 MIM_c38600 2444a8c506645b74e41cec66cd6f0ede 165 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 165 1.6E-57 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 MIM_c38600 2444a8c506645b74e41cec66cd6f0ede 165 PIRSF PIRSF002070 1 164 2.3E-37 T 12-10-2018 MIM_c38600 2444a8c506645b74e41cec66cd6f0ede 165 Pfam PF00436 Single-strand binding protein family 4 109 1.4E-43 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 MIM_c16060 befcc3880644af5473abaeb3165e37bd 311 PIRSF PIRSF037442 1 298 9.1E-99 T 12-10-2018 IPR017208 Uncharacterised conserved protein UCP037442, alpha/beta hydrolase, RSp0795 MIM_c16060 befcc3880644af5473abaeb3165e37bd 311 Pfam PF12146 Serine aminopeptidase, S33 30 246 3.4E-12 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 MIM_c16060 befcc3880644af5473abaeb3165e37bd 311 Gene3D G3DSA:3.40.50.1820 1 294 1.4E-27 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c16060 befcc3880644af5473abaeb3165e37bd 311 SUPERFAMILY SSF53474 5 293 3.3E-31 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c32140 3d0abc3f01ef596307e1d7d3e1d551e0 140 SUPERFAMILY SSF55298 8 132 1.57E-30 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MIM_c32140 3d0abc3f01ef596307e1d7d3e1d551e0 140 Gene3D G3DSA:3.30.1330.40 7 137 1.0E-29 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MIM_c32140 3d0abc3f01ef596307e1d7d3e1d551e0 140 Pfam PF01042 Endoribonuclease L-PSP 28 132 9.5E-22 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 MIM_c25110 21e7facc4741c39ef9411f11f064a38c 161 Pfam PF13463 Winged helix DNA-binding domain 52 102 2.0E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c25110 21e7facc4741c39ef9411f11f064a38c 161 Gene3D G3DSA:1.10.10.10 6 139 2.3E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c25110 21e7facc4741c39ef9411f11f064a38c 161 SUPERFAMILY SSF46785 12 121 4.23E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c09320 fd7e2725eb1ee14e059d6922cf79666f 236 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 66 234 2.0E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c09320 fd7e2725eb1ee14e059d6922cf79666f 236 Gene3D G3DSA:1.10.3720.10 1 235 6.3E-50 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c09320 fd7e2725eb1ee14e059d6922cf79666f 236 SUPERFAMILY SSF161098 14 219 1.02E-36 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c09320 fd7e2725eb1ee14e059d6922cf79666f 236 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 128 2.7E-19 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_24p00240 aecdb332d9654a1f1eef7059fc91df22 86 Pfam PF01402 Ribbon-helix-helix protein, copG family 49 76 1.1E-5 T 12-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 MIM_c38850 019cab6a2a0a9c519f2771612f967b33 184 Pfam PF03473 MOSC domain 60 169 7.5E-5 T 12-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 MIM_c38850 019cab6a2a0a9c519f2771612f967b33 184 SUPERFAMILY SSF50800 2 173 3.56E-38 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily MIM_c38850 019cab6a2a0a9c519f2771612f967b33 184 Gene3D G3DSA:2.40.33.20 1 184 6.1E-32 T 12-10-2018 MIM_c34450 9f1fdf43b6bb49d781184a6cd362ee28 339 Pfam PF02625 XdhC and CoxI family 15 69 3.4E-20 T 12-10-2018 IPR003777 XdhC- CoxI MIM_c34450 9f1fdf43b6bb49d781184a6cd362ee28 339 Gene3D G3DSA:3.40.50.720 169 318 8.8E-42 T 12-10-2018 MIM_c34450 9f1fdf43b6bb49d781184a6cd362ee28 339 Pfam PF13478 XdhC Rossmann domain 170 312 6.6E-36 T 12-10-2018 IPR027051 XdhC Rossmann domain MIM_c11280 56ee0a5dfaeb270dfa7ea36a15a1b0fe 290 SUPERFAMILY SSF161098 50 278 5.23E-53 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c11280 56ee0a5dfaeb270dfa7ea36a15a1b0fe 290 Gene3D G3DSA:1.10.3720.10 46 288 6.9E-66 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c11280 56ee0a5dfaeb270dfa7ea36a15a1b0fe 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 281 2.3E-10 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c38360 fedbc15fc397b91988168a4ac2a227d6 256 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 255 3.4E-49 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c38360 fedbc15fc397b91988168a4ac2a227d6 256 Gene3D G3DSA:3.90.226.10 1 256 3.6E-75 T 12-10-2018 MIM_c38360 fedbc15fc397b91988168a4ac2a227d6 256 SUPERFAMILY SSF52096 2 255 6.4E-75 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c04260 c378577809eafdde56b19eaa27cc81bc 209 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 35 196 2.7E-22 T 12-10-2018 IPR005586 ABC-type transport auxiliary lipoprotein component MIM_c04260 c378577809eafdde56b19eaa27cc81bc 209 Gene3D G3DSA:3.40.50.10610 25 208 9.3E-52 T 12-10-2018 MIM_c04260 c378577809eafdde56b19eaa27cc81bc 209 SUPERFAMILY SSF159594 33 203 2.88E-39 T 12-10-2018 MIM_c18310 fb6dc4233da78d99dfae13670632b6ae 240 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 12 191 9.5E-70 T 12-10-2018 IPR022301 Integral membrane protein YjbE MIM_c18310 fb6dc4233da78d99dfae13670632b6ae 240 Pfam PF03741 Integral membrane protein TerC family 14 190 6.8E-44 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 MIM_c36410 303b7ffc7ee22bab4fcd1668ed13cba5 141 Pfam PF00436 Single-strand binding protein family 5 110 8.1E-11 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 MIM_c36410 303b7ffc7ee22bab4fcd1668ed13cba5 141 Gene3D G3DSA:2.40.50.140 1 122 1.4E-15 T 12-10-2018 MIM_c36410 303b7ffc7ee22bab4fcd1668ed13cba5 141 SUPERFAMILY SSF50249 3 117 1.37E-13 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c10320 cad262e10231b9355a0246a4c89dda9a 128 Pfam PF00085 Thioredoxin 18 86 9.5E-8 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 MIM_c10320 cad262e10231b9355a0246a4c89dda9a 128 Gene3D G3DSA:3.40.30.10 8 107 1.8E-11 T 12-10-2018 MIM_c10320 cad262e10231b9355a0246a4c89dda9a 128 SUPERFAMILY SSF52833 20 101 5.11E-14 T 12-10-2018 IPR036249 Thioredoxin-like superfamily MIM_c35380 c1920f5c0aee3d46b3b1cd0a8f6522c4 285 Gene3D G3DSA:1.10.3720.10 82 275 6.9E-22 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c35380 c1920f5c0aee3d46b3b1cd0a8f6522c4 285 SUPERFAMILY SSF161098 80 266 6.54E-30 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c35380 c1920f5c0aee3d46b3b1cd0a8f6522c4 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 273 1.5E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c10810 7832de731a70e077f19bb78ca02b5905 429 Gene3D G3DSA:1.20.1270.210 49 325 1.3E-10 T 12-10-2018 MIM_c10810 7832de731a70e077f19bb78ca02b5905 429 Gene3D G3DSA:2.40.500.30 72 330 1.3E-10 T 12-10-2018 MIM_c10810 7832de731a70e077f19bb78ca02b5905 429 Gene3D G3DSA:3.30.1120.70 218 266 1.3E-10 T 12-10-2018 MIM_c10810 7832de731a70e077f19bb78ca02b5905 429 Pfam PF04860 Phage portal protein 55 385 2.9E-90 T 12-10-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein MIM_c10810 7832de731a70e077f19bb78ca02b5905 429 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 46 388 1.2E-100 T 12-10-2018 IPR006427 Phage portal protein, HK97 MIM_c39180 d7b4fe0ddb8fae2154bdd13f44607e3e 145 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 6 137 3.7E-19 T 12-10-2018 IPR009936 Protein of unknown function DUF1468 MIM_c36130 cb0cba4bbc1098e4dfb43a64e366796f 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 88 2.9E-5 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MIM_c36130 cb0cba4bbc1098e4dfb43a64e366796f 328 SUPERFAMILY SSF51735 116 289 3.8E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c36130 cb0cba4bbc1098e4dfb43a64e366796f 328 Gene3D G3DSA:3.90.180.10 20 324 1.8E-120 T 12-10-2018 MIM_c36130 cb0cba4bbc1098e4dfb43a64e366796f 328 Gene3D G3DSA:3.40.50.720 126 293 1.8E-120 T 12-10-2018 MIM_c36130 cb0cba4bbc1098e4dfb43a64e366796f 328 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 3 326 1.7E-135 T 12-10-2018 IPR014188 Acrylyl-CoA reductase AcuI MIM_c36130 cb0cba4bbc1098e4dfb43a64e366796f 328 SUPERFAMILY SSF50129 2 145 4.72E-44 T 12-10-2018 IPR011032 GroES-like superfamily MIM_c36130 cb0cba4bbc1098e4dfb43a64e366796f 328 Pfam PF00107 Zinc-binding dehydrogenase 159 282 8.6E-14 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MIM_c36130 cb0cba4bbc1098e4dfb43a64e366796f 328 SMART SM00829 9 324 7.0E-8 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MIM_c12030 0d95db98e21764c5b32f69cf0f445dec 387 Gene3D G3DSA:1.10.540.10 1 119 1.4E-20 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MIM_c12030 0d95db98e21764c5b32f69cf0f445dec 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 2.2E-9 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MIM_c12030 0d95db98e21764c5b32f69cf0f445dec 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 366 6.2E-22 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MIM_c12030 0d95db98e21764c5b32f69cf0f445dec 387 Gene3D G3DSA:2.40.110.10 122 233 1.1E-14 T 12-10-2018 MIM_c12030 0d95db98e21764c5b32f69cf0f445dec 387 Gene3D G3DSA:1.20.140.10 234 386 3.0E-27 T 12-10-2018 MIM_c12030 0d95db98e21764c5b32f69cf0f445dec 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 136 201 7.1E-10 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MIM_c12030 0d95db98e21764c5b32f69cf0f445dec 387 SUPERFAMILY SSF47203 231 378 6.28E-31 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MIM_c12030 0d95db98e21764c5b32f69cf0f445dec 387 SUPERFAMILY SSF56645 1 224 1.57E-37 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MIM_c31740 17419c4a4731e0b92a2294e5d4a9c721 1260 Pfam PF16937 Type III secretion system translocator protein, HrpF 554 710 2.8E-23 T 12-10-2018 IPR031613 Pathogenicity locus protein HrpK MIM_c05000 b7ef3329e96432b90e16cbcbbc583b7d 283 Pfam PF02167 Cytochrome C1 family 39 141 2.3E-11 T 12-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 MIM_c05000 b7ef3329e96432b90e16cbcbbc583b7d 283 Pfam PF02167 Cytochrome C1 family 220 281 1.2E-7 T 12-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 MIM_c05000 b7ef3329e96432b90e16cbcbbc583b7d 283 Gene3D G3DSA:1.10.760.10 27 192 6.1E-16 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c05000 b7ef3329e96432b90e16cbcbbc583b7d 283 SUPERFAMILY SSF46626 18 247 4.58E-49 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c01740 9bc0abe721dc751c3de446d1dcab8546 269 Gene3D G3DSA:3.20.20.60 5 263 6.2E-86 T 12-10-2018 MIM_c01740 9bc0abe721dc751c3de446d1dcab8546 269 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 24 246 4.0E-43 T 12-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 MIM_c01740 9bc0abe721dc751c3de446d1dcab8546 269 SUPERFAMILY SSF51621 7 259 1.23E-75 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MIM_c27610 223ac9343311059c43b781181a6c5e6e 298 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 133 152 - T 12-10-2018 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 MIM_c27610 223ac9343311059c43b781181a6c5e6e 298 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 15 153 5.9E-16 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MIM_c27610 223ac9343311059c43b781181a6c5e6e 298 Gene3D G3DSA:3.10.180.10 11 185 1.6E-29 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c27610 223ac9343311059c43b781181a6c5e6e 298 SUPERFAMILY SSF54593 12 155 7.65E-27 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c09700 7a3be6c75948accaacc818e8051964d4 114 Pfam PF04999 Cell division protein FtsL 5 86 5.6E-15 T 12-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 MIM_c09700 7a3be6c75948accaacc818e8051964d4 114 Hamap MF_00910 Cell division protein FtsL [ftsL]. 2 85 12.931 T 12-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 MIM_c09700 7a3be6c75948accaacc818e8051964d4 114 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 6 85 1.4E-13 T 12-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 MIM_c07550 2aa7da40ec335b06f0b1450400a719a6 487 Pfam PF07690 Major Facilitator Superfamily 20 294 9.1E-30 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c07550 2aa7da40ec335b06f0b1450400a719a6 487 Gene3D G3DSA:1.20.1250.20 9 256 1.1E-32 T 12-10-2018 MIM_c07550 2aa7da40ec335b06f0b1450400a719a6 487 SUPERFAMILY SSF103473 13 433 1.7E-50 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c07550 2aa7da40ec335b06f0b1450400a719a6 487 Gene3D G3DSA:1.20.1250.20 272 486 3.6E-18 T 12-10-2018 MIM_c03620 c23dea508508a17847bf1dd7c143fdb4 362 Pfam PF06032 Protein of unknown function (DUF917) 8 332 2.2E-57 T 12-10-2018 IPR010318 Protein of unknown function DUF917 MIM_c03620 c23dea508508a17847bf1dd7c143fdb4 362 SUPERFAMILY SSF160991 3 355 2.62E-79 T 12-10-2018 MIM_c03620 c23dea508508a17847bf1dd7c143fdb4 362 Gene3D G3DSA:3.40.1610.10 3 225 7.6E-20 T 12-10-2018 IPR027479 Protein of unknown function DUF917, N-terminal MIM_c37770 cb32d66c8a7346d54aa06bb9291b7e9b 333 SUPERFAMILY SSF51126 16 262 1.24E-24 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor MIM_c37770 cb32d66c8a7346d54aa06bb9291b7e9b 333 Gene3D G3DSA:2.160.20.10 30 278 5.7E-20 T 12-10-2018 IPR012334 Pectin lyase fold MIM_c37770 cb32d66c8a7346d54aa06bb9291b7e9b 333 Pfam PF13229 Right handed beta helix region 124 262 3.0E-6 T 12-10-2018 IPR039448 Right handed beta helix domain MIM_c31730 b84793215317ff5421d2356af73afd7c 195 SUPERFAMILY SSF52499 3 183 2.75E-38 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MIM_c31730 b84793215317ff5421d2356af73afd7c 195 Pfam PF00857 Isochorismatase family 12 167 1.6E-19 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 MIM_c31730 b84793215317ff5421d2356af73afd7c 195 Gene3D G3DSA:3.40.50.850 1 194 3.5E-40 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MIM_c24850 da3c8dbb4eb2890146281c857f0759c3 270 Gene3D G3DSA:1.10.12.10 215 269 4.7E-8 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MIM_c24850 da3c8dbb4eb2890146281c857f0759c3 270 SUPERFAMILY SSF52096 1 269 7.8E-76 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MIM_c24850 da3c8dbb4eb2890146281c857f0759c3 270 Gene3D G3DSA:3.90.226.10 1 209 7.2E-66 T 12-10-2018 MIM_c24850 da3c8dbb4eb2890146281c857f0759c3 270 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 268 2.4E-56 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MIM_c02690 bcdbd507e20957eaa6a69c75f1d70bb2 139 SUPERFAMILY SSF51182 19 130 1.57E-25 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c02690 bcdbd507e20957eaa6a69c75f1d70bb2 139 Gene3D G3DSA:2.60.120.10 25 137 3.6E-21 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c02690 bcdbd507e20957eaa6a69c75f1d70bb2 139 Pfam PF07883 Cupin domain 58 125 1.8E-16 T 12-10-2018 IPR013096 Cupin 2, conserved barrel MIM_c00430 df1d685057df1ff4da8c44bff7b288de 269 SUPERFAMILY SSF53850 26 247 6.64E-67 T 12-10-2018 MIM_c00430 df1d685057df1ff4da8c44bff7b288de 269 Gene3D G3DSA:3.40.190.10 107 213 5.3E-76 T 12-10-2018 MIM_c00430 df1d685057df1ff4da8c44bff7b288de 269 Pfam PF03180 NLPA lipoprotein 27 256 9.9E-72 T 12-10-2018 IPR004872 Lipoprotein NlpA family MIM_c00430 df1d685057df1ff4da8c44bff7b288de 269 Gene3D G3DSA:3.40.190.10 28 245 5.3E-76 T 12-10-2018 MIM_c01920 6173a5738d5eaec754e91fc2f53678f2 182 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 21 151 2.2E-31 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ MIM_c20780 17887c9b8aa72b92399e50793f6a494f 345 Pfam PF02653 Branched-chain amino acid transport system / permease component 40 284 4.6E-37 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c21510 c81c786acc3b47a0b8dce6c30f443a44 158 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 58 95 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MIM_c21510 c81c786acc3b47a0b8dce6c30f443a44 158 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 12 154 46.057 T 12-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 MIM_c21510 c81c786acc3b47a0b8dce6c30f443a44 158 Gene3D G3DSA:3.40.140.10 2 158 1.7E-61 T 12-10-2018 MIM_c21510 c81c786acc3b47a0b8dce6c30f443a44 158 Pfam PF14437 MafB19-like deaminase 7 154 3.3E-31 T 12-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 MIM_c21510 c81c786acc3b47a0b8dce6c30f443a44 158 SUPERFAMILY SSF53927 6 155 3.33E-56 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 MIM_c15100 e91c2b8cd1a1d09257bdee79866d628a 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 294 3.0E-13 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c15100 e91c2b8cd1a1d09257bdee79866d628a 304 SUPERFAMILY SSF161098 15 293 9.35E-55 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c15100 e91c2b8cd1a1d09257bdee79866d628a 304 Gene3D G3DSA:1.10.3720.10 17 300 2.5E-53 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c17220 1630ae3cd45d96fc9fd1afdbccdf36df 505 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 441 5.1E-140 T 12-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane MIM_c38660 42fe3ff958e552a8fd6c27c594924b5d 377 SUPERFAMILY SSF56796 5 350 7.85E-111 T 12-10-2018 MIM_c38660 42fe3ff958e552a8fd6c27c594924b5d 377 Gene3D G3DSA:1.20.1090.10 172 357 9.7E-61 T 12-10-2018 MIM_c38660 42fe3ff958e552a8fd6c27c594924b5d 377 Pfam PF01761 3-dehydroquinate synthase 66 323 3.9E-104 T 12-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MIM_c38660 42fe3ff958e552a8fd6c27c594924b5d 377 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 353 68.504 T 12-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MIM_c38660 42fe3ff958e552a8fd6c27c594924b5d 377 PIRSF PIRSF001455 9 359 3.4E-108 T 12-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MIM_c38660 42fe3ff958e552a8fd6c27c594924b5d 377 Gene3D G3DSA:3.40.50.1970 1 171 1.8E-61 T 12-10-2018 MIM_c38660 42fe3ff958e552a8fd6c27c594924b5d 377 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 342 5.9E-116 T 12-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MIM_c05020 1e1f04337c2653ac3698c1bb6ca21a2b 142 PIRSF PIRSF005276 1 142 8.5E-48 T 12-10-2018 IPR007481 Stringent starvation protein B MIM_c05020 1e1f04337c2653ac3698c1bb6ca21a2b 142 Pfam PF04386 Stringent starvation protein B 5 142 8.4E-32 T 12-10-2018 IPR007481 Stringent starvation protein B MIM_c05020 1e1f04337c2653ac3698c1bb6ca21a2b 142 SUPERFAMILY SSF101738 3 111 2.22E-41 T 12-10-2018 IPR036760 SspB-like superfamily MIM_c05020 1e1f04337c2653ac3698c1bb6ca21a2b 142 Gene3D G3DSA:2.30.30.220 1 124 3.1E-46 T 12-10-2018 IPR036760 SspB-like superfamily MIM_c05610 9e5b4628fd5b5d11142c3ece9a374389 179 SUPERFAMILY SSF53271 13 178 1.97E-52 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like MIM_c05610 9e5b4628fd5b5d11142c3ece9a374389 179 Gene3D G3DSA:3.40.50.2020 5 179 2.9E-63 T 12-10-2018 MIM_c05610 9e5b4628fd5b5d11142c3ece9a374389 179 Pfam PF00156 Phosphoribosyl transferase domain 51 159 8.0E-17 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MIM_c05610 9e5b4628fd5b5d11142c3ece9a374389 179 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 12 178 1.5E-67 T 12-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 MIM_c05610 9e5b4628fd5b5d11142c3ece9a374389 179 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 10 179 36.939 T 12-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 MIM_c34560 2f17c9abfb174463765d203002a4bb64 280 Gene3D G3DSA:1.10.3720.10 9 263 4.4E-47 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c34560 2f17c9abfb174463765d203002a4bb64 280 SUPERFAMILY SSF161098 10 267 3.55E-54 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c34560 2f17c9abfb174463765d203002a4bb64 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 274 1.3E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c05050 dc7cf00c2a66f390eb1987363b32a7ce 97 Pfam PF11604 Copper binding periplasmic protein CusF 32 96 3.1E-19 T 12-10-2018 IPR021647 Copper binding periplasmic protein CusF MIM_c05050 dc7cf00c2a66f390eb1987363b32a7ce 97 Gene3D G3DSA:2.40.50.320 27 97 4.7E-17 T 12-10-2018 MIM_c20800 8d69ad9044bd1ac9cf69e530a54d1b78 348 Pfam PF04909 Amidohydrolase 112 346 3.8E-27 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MIM_c20800 8d69ad9044bd1ac9cf69e530a54d1b78 348 Gene3D G3DSA:3.20.20.140 34 348 6.4E-69 T 12-10-2018 MIM_c20800 8d69ad9044bd1ac9cf69e530a54d1b78 348 SUPERFAMILY SSF51556 35 346 3.49E-29 T 12-10-2018 IPR032466 Metal-dependent hydrolase MIM_c06580 303d9e11519dd58e9bf09e30d6e696b5 304 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 20 303 26.328 T 12-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 MIM_c06580 303d9e11519dd58e9bf09e30d6e696b5 304 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 25 300 4.4E-94 T 12-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 MIM_c06580 303d9e11519dd58e9bf09e30d6e696b5 304 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 82 104 - T 12-10-2018 IPR030470 UbiA prenyltransferase conserved site MIM_c06580 303d9e11519dd58e9bf09e30d6e696b5 304 Gene3D G3DSA:1.10.357.140 40 186 4.0E-43 T 12-10-2018 MIM_c06580 303d9e11519dd58e9bf09e30d6e696b5 304 Pfam PF01040 UbiA prenyltransferase family 44 289 5.1E-53 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 MIM_c06580 303d9e11519dd58e9bf09e30d6e696b5 304 Gene3D G3DSA:1.20.120.1780 187 303 6.5E-14 T 12-10-2018 MIM_c04090 782f4965a8d1fdff934e9d0dd66ebf2a 177 Pfam PF08281 Sigma-70, region 4 112 161 1.1E-12 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MIM_c04090 782f4965a8d1fdff934e9d0dd66ebf2a 177 SUPERFAMILY SSF88659 103 164 1.87E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MIM_c04090 782f4965a8d1fdff934e9d0dd66ebf2a 177 Pfam PF04542 Sigma-70 region 2 20 85 7.1E-9 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MIM_c04090 782f4965a8d1fdff934e9d0dd66ebf2a 177 Gene3D G3DSA:1.10.10.10 106 167 1.9E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c04090 782f4965a8d1fdff934e9d0dd66ebf2a 177 Gene3D G3DSA:1.10.1740.10 11 87 3.3E-15 T 12-10-2018 MIM_c04090 782f4965a8d1fdff934e9d0dd66ebf2a 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 163 3.4E-20 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MIM_c04090 782f4965a8d1fdff934e9d0dd66ebf2a 177 SUPERFAMILY SSF88946 19 100 5.49E-15 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MIM_c23470 38b9c339d3fbbbcffa1d5d8efd249a6b 465 TIGRFAM TIGR00797 matE: MATE efflux family protein 23 412 4.4E-66 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MIM_c23470 38b9c339d3fbbbcffa1d5d8efd249a6b 465 Pfam PF01554 MatE 23 183 3.0E-21 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MIM_c23470 38b9c339d3fbbbcffa1d5d8efd249a6b 465 Pfam PF01554 MatE 248 406 1.5E-22 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MIM_c23470 38b9c339d3fbbbcffa1d5d8efd249a6b 465 PIRSF PIRSF006603 4 465 8.1E-55 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MIM_c09200 fc244ad6363ff8675313069f761f2a44 263 Pfam PF01478 Type IV leader peptidase family 81 191 1.6E-11 T 12-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 MIM_c04250 430b5ba4addc7befb8abdcf699e317fe 312 Pfam PF02470 MlaD protein 38 115 6.1E-12 T 12-10-2018 IPR003399 Mce/MlaD MIM_c10790 58255f205973723ac41aa2131e08a8d2 160 Pfam PF05119 Phage terminase, small subunit 53 145 7.1E-23 T 12-10-2018 IPR006448 Putative phage terminase, small subunit, P27 family MIM_c10790 58255f205973723ac41aa2131e08a8d2 160 TIGRFAM TIGR01558 sm_term_P27: putative phage terminase, small subunit, P27 family 44 155 2.6E-28 T 12-10-2018 IPR006448 Putative phage terminase, small subunit, P27 family MIM_c28060 839d8af5759b4293fa66abfdd9278474 99 Gene3D G3DSA:3.10.450.40 25 99 2.3E-14 T 12-10-2018 MIM_c28060 839d8af5759b4293fa66abfdd9278474 99 Pfam PF03413 Peptidase propeptide and YPEB domain 36 93 1.4E-10 T 12-10-2018 IPR025711 PepSY domain MIM_c08210 ba116905650e323b66c363d24d71c99c 270 SUPERFAMILY SSF56112 27 256 2.19E-29 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily MIM_c08210 ba116905650e323b66c363d24d71c99c 270 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 8 245 3.0E-73 T 12-10-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 MIM_c04310 dcc07cc227384db3f0f12652338ec91c 300 Gene3D G3DSA:3.20.20.60 1 291 5.5E-102 T 12-10-2018 MIM_c04310 dcc07cc227384db3f0f12652338ec91c 300 Pfam PF13714 Phosphoenolpyruvate phosphomutase 8 249 2.0E-54 T 12-10-2018 MIM_c04310 dcc07cc227384db3f0f12652338ec91c 300 SUPERFAMILY SSF51621 4 273 3.54E-89 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MIM_c04310 dcc07cc227384db3f0f12652338ec91c 300 ProSitePatterns PS00161 Isocitrate lyase signature. 117 122 - T 12-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 MIM_c09050 2d041b93f5982082803b98259c4c7789 301 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 10 275 8.0E-42 T 12-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 MIM_c09050 2d041b93f5982082803b98259c4c7789 301 Gene3D G3DSA:2.40.10.350 185 262 1.2E-30 T 12-10-2018 MIM_c09050 2d041b93f5982082803b98259c4c7789 301 Gene3D G3DSA:2.40.10.340 127 271 1.2E-30 T 12-10-2018 MIM_c09050 2d041b93f5982082803b98259c4c7789 301 Pfam PF04085 rod shape-determining protein MreC 129 274 4.8E-35 T 12-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 MIM_c09050 2d041b93f5982082803b98259c4c7789 301 PIRSF PIRSF038471 7 288 5.7E-64 T 12-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 MIM_c10360 5f3d57c64c2f40e7cac02582c0e12e12 193 Pfam PF09361 Phasin protein 7 105 2.0E-24 T 12-10-2018 IPR018968 Phasin MIM_c10360 5f3d57c64c2f40e7cac02582c0e12e12 193 TIGRFAM TIGR01841 phasin: phasin family protein 27 112 9.1E-22 T 12-10-2018 IPR010127 Phasin, subfamily 1 MIM_c06830 ee2a7b9581e82c54d644d2341942e87a 401 Pfam PF02397 Bacterial sugar transferase 213 395 3.9E-59 T 12-10-2018 IPR003362 Bacterial sugar transferase MIM_c25820 926df02327986e6dea76c01469ad8b68 442 Gene3D G3DSA:3.50.50.60 2 426 9.2E-110 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c25820 926df02327986e6dea76c01469ad8b68 442 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 10 342 1.3E-110 T 12-10-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase MIM_c25820 926df02327986e6dea76c01469ad8b68 442 SUPERFAMILY SSF51905 8 260 4.59E-20 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c26880 7d32972dece5519bffe29f5e46846c2d 266 Gene3D G3DSA:3.40.50.720 2 266 8.1E-84 T 12-10-2018 MIM_c26880 7d32972dece5519bffe29f5e46846c2d 266 Pfam PF00899 ThiF family 19 262 3.8E-32 T 12-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MIM_c26880 7d32972dece5519bffe29f5e46846c2d 266 SUPERFAMILY SSF69572 7 264 1.02E-55 T 12-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 MIM_c32040 73fde8c4c31b12d57e3571c0b2624ef6 218 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 36 128 2.6E-13 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MIM_c32040 73fde8c4c31b12d57e3571c0b2624ef6 218 SUPERFAMILY SSF50475 34 134 1.31E-13 T 12-10-2018 MIM_c32040 73fde8c4c31b12d57e3571c0b2624ef6 218 Gene3D G3DSA:2.30.110.10 25 149 1.2E-23 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MIM_c34690 4f51ea4e5e4651fe9b16ba3477d1ee05 286 SUPERFAMILY SSF56529 63 283 6.8E-72 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MIM_c34690 4f51ea4e5e4651fe9b16ba3477d1ee05 286 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 75 283 2.3E-59 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 MIM_c34690 4f51ea4e5e4651fe9b16ba3477d1ee05 286 Gene3D G3DSA:3.90.850.10 70 286 1.3E-75 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MIM_c17000 7200f82f6b84286d922577c1fefd9a9f 321 Pfam PF00892 EamA-like transporter family 172 305 1.2E-14 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MIM_c17000 7200f82f6b84286d922577c1fefd9a9f 321 Pfam PF00892 EamA-like transporter family 30 163 3.5E-7 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MIM_c17000 7200f82f6b84286d922577c1fefd9a9f 321 SUPERFAMILY SSF103481 209 311 1.57E-12 T 12-10-2018 MIM_c17000 7200f82f6b84286d922577c1fefd9a9f 321 SUPERFAMILY SSF103481 79 167 4.05E-9 T 12-10-2018 MIM_c39920 f87f97124b82c66ef64969b7513b903c 862 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 529 842 9.4E-53 T 12-10-2018 IPR007296 Domain of unknown function DUF403 MIM_c39920 f87f97124b82c66ef64969b7513b903c 862 Gene3D G3DSA:3.40.50.11290 221 318 4.5E-32 T 12-10-2018 MIM_c39920 f87f97124b82c66ef64969b7513b903c 862 SUPERFAMILY SSF56059 28 426 1.87E-18 T 12-10-2018 MIM_c39920 f87f97124b82c66ef64969b7513b903c 862 Pfam PF14403 Circularly permuted ATP-grasp type 2 83 461 4.0E-133 T 12-10-2018 IPR025841 Circularly permuted ATP-grasp type 2 MIM_c36960 6f8e78155e064d00f10fb94a12cacb08 624 Gene3D G3DSA:2.170.130.10 34 161 3.8E-33 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MIM_c36960 6f8e78155e064d00f10fb94a12cacb08 624 Gene3D G3DSA:2.40.170.20 170 623 1.4E-93 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MIM_c36960 6f8e78155e064d00f10fb94a12cacb08 624 Pfam PF00593 TonB dependent receptor 197 622 3.2E-37 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MIM_c36960 6f8e78155e064d00f10fb94a12cacb08 624 SUPERFAMILY SSF56935 37 622 3.09E-106 T 12-10-2018 MIM_c36960 6f8e78155e064d00f10fb94a12cacb08 624 Pfam PF07715 TonB-dependent Receptor Plug Domain 55 156 6.3E-27 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain MIM_c02170 b0a40e3ba90774add8b88512de16ee75 214 Gene3D G3DSA:1.10.357.10 1 169 3.1E-17 T 12-10-2018 MIM_c02170 b0a40e3ba90774add8b88512de16ee75 214 SUPERFAMILY SSF46689 2 60 8.98E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MIM_c02170 b0a40e3ba90774add8b88512de16ee75 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 2.5E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c02170 b0a40e3ba90774add8b88512de16ee75 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 4.7E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c02170 b0a40e3ba90774add8b88512de16ee75 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 4.7E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MIM_c18350 e2336947a57d732aa9b5296b28406c32 470 Gene3D G3DSA:1.25.40.10 161 396 3.7E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MIM_c18350 e2336947a57d732aa9b5296b28406c32 470 SUPERFAMILY SSF48452 87 391 3.8E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MIM_c18350 e2336947a57d732aa9b5296b28406c32 470 TIGRFAM TIGR00540 TPR_hemY_coli: heme biosynthesis-associated TPR protein 5 388 1.2E-77 T 12-10-2018 IPR005254 Heme biosynthesis-associated TPR protein GO:0016020|GO:0042168 MIM_c18350 e2336947a57d732aa9b5296b28406c32 470 Pfam PF07219 HemY protein N-terminus 26 134 1.8E-24 T 12-10-2018 IPR010817 HemY, N-terminal MIM_c32350 973fb1b15a4141c291f38d154f665fa9 142 Pfam PF02472 Biopolymer transport protein ExbD/TolR 10 131 3.9E-25 T 12-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 MIM_c32350 973fb1b15a4141c291f38d154f665fa9 142 Gene3D G3DSA:3.30.420.270 61 130 5.4E-23 T 12-10-2018 MIM_c31080 787f8d98960a124bc85c76c92710cbba 348 SUPERFAMILY SSF144052 138 340 3.27E-14 T 12-10-2018 MIM_c17570 099b0745ffda01f7d19445b44bc397dc 251 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 47 248 4.5E-59 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 MIM_c17570 099b0745ffda01f7d19445b44bc397dc 251 SUPERFAMILY SSF56529 36 249 3.92E-74 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MIM_c17570 099b0745ffda01f7d19445b44bc397dc 251 TIGRFAM TIGR02303 HpaG-C-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit 2 250 6.4E-106 T 12-10-2018 IPR012684 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit GO:0008704|GO:0018800|GO:1901023 KEGG: 00350+5.3.3.10+4.1.1.68 MIM_c17570 099b0745ffda01f7d19445b44bc397dc 251 Gene3D G3DSA:3.90.850.10 39 251 2.1E-74 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MIM_c40830 eb7c2b8abaa754f9b6102a6d4df98d78 343 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 9 160 8.8E-37 T 12-10-2018 IPR017516 AbrB duplication MIM_c40830 eb7c2b8abaa754f9b6102a6d4df98d78 343 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 182 336 2.0E-35 T 12-10-2018 IPR017516 AbrB duplication MIM_c40830 eb7c2b8abaa754f9b6102a6d4df98d78 343 Pfam PF05145 Transition state regulatory protein AbrB 28 336 8.8E-85 T 12-10-2018 IPR007820 AbrB family GO:0010468|GO:0016021 MIM_c40830 eb7c2b8abaa754f9b6102a6d4df98d78 343 PIRSF PIRSF038991 1 342 1.0E-77 T 12-10-2018 IPR007820 AbrB family GO:0010468|GO:0016021 MIM_c31980 ee4f734648447df13b4f10062f0b3085 519 Gene3D G3DSA:3.30.420.10 256 467 1.9E-14 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MIM_c31980 ee4f734648447df13b4f10062f0b3085 519 SUPERFAMILY SSF53098 258 401 3.03E-10 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily MIM_c31980 ee4f734648447df13b4f10062f0b3085 519 Pfam PF00665 Integrase core domain 261 391 8.3E-10 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 MIM_c29640 5e9247f133fb99605de46adef5980d92 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 27.266 T 12-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c29640 5e9247f133fb99605de46adef5980d92 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 9.9E-37 T 12-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c29640 5e9247f133fb99605de46adef5980d92 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 3.6E-40 T 12-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c29640 5e9247f133fb99605de46adef5980d92 103 SUPERFAMILY SSF141091 1 101 7.85E-39 T 12-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c29640 5e9247f133fb99605de46adef5980d92 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 12-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c16630 822a1f7d7a6f32534e6cb0735ceee013 268 Gene3D G3DSA:3.60.21.10 1 262 1.3E-30 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like MIM_c16630 822a1f7d7a6f32534e6cb0735ceee013 268 Pfam PF00149 Calcineurin-like phosphoesterase 3 191 7.5E-17 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MIM_c16630 822a1f7d7a6f32534e6cb0735ceee013 268 SUPERFAMILY SSF56300 3 248 3.14E-46 T 12-10-2018 MIM_c29210 abc186ad36207146452286650d3dd232 166 Pfam PF03477 ATP cone domain 51 136 2.6E-15 T 12-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 MIM_c29210 abc186ad36207146452286650d3dd232 166 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 146 9.0E-60 T 12-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 MIM_c29210 abc186ad36207146452286650d3dd232 166 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 83.035 T 12-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 MIM_c34640 2a217f90f1f28088258dcb02ca929cae 254 Gene3D G3DSA:1.10.3720.10 55 251 1.3E-25 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c34640 2a217f90f1f28088258dcb02ca929cae 254 SUPERFAMILY SSF161098 55 244 1.83E-31 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c34640 2a217f90f1f28088258dcb02ca929cae 254 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 247 9.6E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_24p00220 bc04ebd76b1b82e0adc2d831cd308549 85 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 1 83 1.1E-19 T 12-10-2018 IPR007337 RelB antitoxin/Antitoxin DinJ MIM_24p00220 bc04ebd76b1b82e0adc2d831cd308549 85 Gene3D G3DSA:1.10.1220.10 5 81 3.1E-14 T 12-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 MIM_24p00220 bc04ebd76b1b82e0adc2d831cd308549 85 Pfam PF04221 RelB antitoxin 6 75 5.5E-19 T 12-10-2018 IPR007337 RelB antitoxin/Antitoxin DinJ MIM_24p00220 bc04ebd76b1b82e0adc2d831cd308549 85 PIRSF PIRSF003108 1 85 1.2E-25 T 12-10-2018 IPR026262 Antitoxin DinJ GO:0000986|GO:0015643|GO:0044010 MIM_c30260 cae1cb589f7ddcc55b2d7e2c8eae1a92 204 Gene3D G3DSA:3.40.109.10 3 200 6.5E-45 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MIM_c30260 cae1cb589f7ddcc55b2d7e2c8eae1a92 204 Pfam PF00881 Nitroreductase family 18 199 8.2E-22 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MIM_c30260 cae1cb589f7ddcc55b2d7e2c8eae1a92 204 SUPERFAMILY SSF55469 14 199 9.11E-27 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MIM_c19290 fad92e1d32624466ca2de35d6273c8f4 162 Gene3D G3DSA:1.20.1550.10 1 160 3.4E-23 T 12-10-2018 IPR023380 DsbB-like superfamily MIM_c19290 fad92e1d32624466ca2de35d6273c8f4 162 SUPERFAMILY SSF158442 8 151 3.27E-22 T 12-10-2018 IPR023380 DsbB-like superfamily MIM_c19290 fad92e1d32624466ca2de35d6273c8f4 162 Pfam PF02600 Disulfide bond formation protein DsbB 6 149 3.5E-28 T 12-10-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 MIM_c25150 cbe7c1a3c4d6bfcb0064852ddefe4c1c 527 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 71 433 1.6E-52 T 12-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 MIM_c25150 cbe7c1a3c4d6bfcb0064852ddefe4c1c 527 SUPERFAMILY SSF53383 64 513 1.24E-105 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MIM_c25150 cbe7c1a3c4d6bfcb0064852ddefe4c1c 527 Gene3D G3DSA:3.90.1150.170 68 507 6.5E-93 T 12-10-2018 MIM_c25150 cbe7c1a3c4d6bfcb0064852ddefe4c1c 527 Gene3D G3DSA:3.40.640.10 127 378 6.5E-93 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MIM_c08040 04be0f31fc4cd4ef2270fadd12eabfbf 298 SUPERFAMILY SSF161098 93 280 6.67E-20 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c08040 04be0f31fc4cd4ef2270fadd12eabfbf 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 294 6.3E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c08040 04be0f31fc4cd4ef2270fadd12eabfbf 298 Gene3D G3DSA:1.10.3720.10 88 296 4.4E-14 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c08040 04be0f31fc4cd4ef2270fadd12eabfbf 298 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 23 70 5.0E-12 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MIM_c07400 2bf4129ab90dd4c917580331d7291faa 541 SUPERFAMILY SSF51261 372 539 6.28E-44 T 12-10-2018 IPR011055 Duplicated hybrid motif MIM_c07400 2bf4129ab90dd4c917580331d7291faa 541 SUPERFAMILY SSF90250 46 94 6.02E-5 T 12-10-2018 MIM_c07400 2bf4129ab90dd4c917580331d7291faa 541 Gene3D G3DSA:2.70.70.10 400 541 8.4E-33 T 12-10-2018 IPR011055 Duplicated hybrid motif MIM_c07400 2bf4129ab90dd4c917580331d7291faa 541 Pfam PF01551 Peptidase family M23 442 535 2.6E-25 T 12-10-2018 IPR016047 Peptidase M23 MIM_c39490 81643a9429cf8b09082cbd0e38eb741b 155 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 9 146 5.0E-19 T 12-10-2018 IPR009936 Protein of unknown function DUF1468 MIM_c40690 f711aa75b830af49d5ef16ee101144fb 126 Hamap MF_00422 Protein translocase subunit SecE [secE]. 65 121 11.931 T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MIM_c40690 f711aa75b830af49d5ef16ee101144fb 126 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 68 121 3.3E-18 T 12-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 MIM_c40690 f711aa75b830af49d5ef16ee101144fb 126 Gene3D G3DSA:1.20.5.1030 65 121 4.5E-16 T 12-10-2018 IPR038379 SecE superfamily MIM_c40690 f711aa75b830af49d5ef16ee101144fb 126 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 69 119 1.6E-19 T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MIM_c19980 7ba186c4c6818ee3df68afadafd6df54 312 SUPERFAMILY SSF53850 87 290 3.48E-29 T 12-10-2018 MIM_c19980 7ba186c4c6818ee3df68afadafd6df54 312 Pfam PF03466 LysR substrate binding domain 88 289 2.4E-26 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c19980 7ba186c4c6818ee3df68afadafd6df54 312 Gene3D G3DSA:1.10.10.10 2 88 1.8E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c19980 7ba186c4c6818ee3df68afadafd6df54 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.0E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c19980 7ba186c4c6818ee3df68afadafd6df54 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 4.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c19980 7ba186c4c6818ee3df68afadafd6df54 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 4.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c19980 7ba186c4c6818ee3df68afadafd6df54 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 4.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c19980 7ba186c4c6818ee3df68afadafd6df54 312 Gene3D G3DSA:3.40.190.10 95 263 5.2E-19 T 12-10-2018 MIM_c19980 7ba186c4c6818ee3df68afadafd6df54 312 Gene3D G3DSA:3.40.190.10 163 262 5.2E-19 T 12-10-2018 MIM_c19980 7ba186c4c6818ee3df68afadafd6df54 312 SUPERFAMILY SSF46785 1 109 2.9E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c37290 84f331ac211516ecd3ea328ca47615e8 84 SUPERFAMILY SSF89447 5 61 2.77E-7 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily MIM_c37290 84f331ac211516ecd3ea328ca47615e8 84 Gene3D G3DSA:2.10.260.10 2 83 1.9E-21 T 12-10-2018 MIM_c37290 84f331ac211516ecd3ea328ca47615e8 84 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 10 54 5.7E-8 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MIM_c28740 d8a8f0ccde3fb3695d382ccd15cc073d 216 Pfam PF12059 Protein of unknown function (DUF3540) 19 216 2.2E-67 T 12-10-2018 IPR021927 Protein of unknown function DUF3540 MIM_c37660 20c08e9603696585d0dccb30f36ee4c2 619 Gene3D G3DSA:3.40.50.2000 433 593 1.1E-6 T 12-10-2018 MIM_c28350 13af6559188f79a285357571c5a13557 385 Gene3D G3DSA:3.40.630.10 9 297 1.6E-71 T 12-10-2018 MIM_c28350 13af6559188f79a285357571c5a13557 385 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 38 365 6.0E-16 T 12-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 MIM_c28350 13af6559188f79a285357571c5a13557 385 SUPERFAMILY SSF53187 12 365 1.55E-30 T 12-10-2018 MIM_c32690 e80904aa9e865ac47490302cbff7a180 389 Gene3D G3DSA:3.40.50.2300 146 382 4.2E-93 T 12-10-2018 MIM_c32690 e80904aa9e865ac47490302cbff7a180 389 Gene3D G3DSA:3.40.50.2300 30 369 4.2E-93 T 12-10-2018 MIM_c32690 e80904aa9e865ac47490302cbff7a180 389 Pfam PF13458 Periplasmic binding protein 27 363 4.5E-47 T 12-10-2018 IPR028081 Leucine-binding protein domain MIM_c32690 e80904aa9e865ac47490302cbff7a180 389 SUPERFAMILY SSF53822 26 386 1.71E-63 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c30030 87f7184d21ed0a3cb4319ed6878ff4c0 180 Gene3D G3DSA:2.60.40.1890 62 174 1.8E-26 T 12-10-2018 IPR036182 Copper chaperone PCuAC superfamily MIM_c30030 87f7184d21ed0a3cb4319ed6878ff4c0 180 SUPERFAMILY SSF110087 46 172 3.53E-28 T 12-10-2018 IPR036182 Copper chaperone PCuAC superfamily MIM_c30030 87f7184d21ed0a3cb4319ed6878ff4c0 180 Pfam PF04314 Copper chaperone PCu(A)C 57 165 8.5E-24 T 12-10-2018 IPR007410 Copper chaperone PCuAC MIM_c34920 e4f6e49061f7847115a053aabcb5122d 278 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 37 216 3.4E-33 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal MIM_c34920 e4f6e49061f7847115a053aabcb5122d 278 SUPERFAMILY SSF53639 31 247 4.71E-49 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily MIM_c34920 e4f6e49061f7847115a053aabcb5122d 278 SMART SM01007 36 217 2.4E-33 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal MIM_c34920 e4f6e49061f7847115a053aabcb5122d 278 Gene3D G3DSA:3.40.225.10 24 278 7.0E-58 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily MIM_c13300 366c6e57175ec8773c523aaebe33d2f1 250 SUPERFAMILY SSF48371 78 249 3.13E-37 T 12-10-2018 IPR016024 Armadillo-type fold MIM_c13300 366c6e57175ec8773c523aaebe33d2f1 250 Pfam PF13646 HEAT repeats 82 163 2.3E-6 T 12-10-2018 MIM_c13300 366c6e57175ec8773c523aaebe33d2f1 250 Gene3D G3DSA:1.25.40.290 130 250 4.9E-30 T 12-10-2018 MIM_c10050 b2720cc395952724047a13c8ecea1c07 111 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 6 105 1.6E-14 T 12-10-2018 IPR008407 Branched-chain amino acid transport, AzlD MIM_c06000 71f47df5f123e6b892f88f901e8f9d0f 315 Gene3D G3DSA:2.120.10.30 15 314 1.3E-102 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MIM_c06000 71f47df5f123e6b892f88f901e8f9d0f 315 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 42 299 4.5E-65 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region MIM_c06000 71f47df5f123e6b892f88f901e8f9d0f 315 SUPERFAMILY SSF63829 8 312 1.02E-67 T 12-10-2018 MIM_c06000 71f47df5f123e6b892f88f901e8f9d0f 315 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 281 299 1.7E-12 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MIM_c06000 71f47df5f123e6b892f88f901e8f9d0f 315 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 173 195 1.7E-12 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MIM_c06000 71f47df5f123e6b892f88f901e8f9d0f 315 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 236 253 1.7E-12 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MIM_c06000 71f47df5f123e6b892f88f901e8f9d0f 315 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 43 60 1.7E-12 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MIM_c28020 f25860dab9a6d5dc7484b83ffa1e23e0 537 Pfam PF00795 Carbon-nitrogen hydrolase 231 494 4.4E-24 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 MIM_c28020 f25860dab9a6d5dc7484b83ffa1e23e0 537 Gene3D G3DSA:3.60.110.10 241 497 2.6E-14 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MIM_c28020 f25860dab9a6d5dc7484b83ffa1e23e0 537 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 1 514 21.024 T 12-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 MIM_c28020 f25860dab9a6d5dc7484b83ffa1e23e0 537 SUPERFAMILY SSF56317 227 506 1.31E-34 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MIM_c28020 f25860dab9a6d5dc7484b83ffa1e23e0 537 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 58 476 3.7E-83 T 12-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 MIM_c05310 cb8a59efce5f1ba9d11438e9e354f8e9 418 Gene3D G3DSA:3.40.50.12710 9 418 3.5E-112 T 12-10-2018 IPR038375 Protein arginine methyltransferase NDUFAF7 superfamily Reactome: R-HSA-6799198 MIM_c05310 cb8a59efce5f1ba9d11438e9e354f8e9 418 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 94 346 6.0E-47 T 12-10-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 MIM_c05310 cb8a59efce5f1ba9d11438e9e354f8e9 418 SUPERFAMILY SSF53335 39 409 2.23E-84 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c12900 21b652ca8fa396624b9a806202f9cb67 318 SUPERFAMILY SSF103481 53 156 1.7E-12 T 12-10-2018 MIM_c12900 21b652ca8fa396624b9a806202f9cb67 318 Pfam PF00892 EamA-like transporter family 24 152 3.7E-19 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MIM_c12900 21b652ca8fa396624b9a806202f9cb67 318 Pfam PF00892 EamA-like transporter family 168 300 1.5E-16 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MIM_c12900 21b652ca8fa396624b9a806202f9cb67 318 SUPERFAMILY SSF103481 201 305 2.09E-11 T 12-10-2018 MIM_c32400 e98e99770e7be07c20406af1f3eaae90 246 Pfam PF02517 CAAX protease self-immunity 87 233 6.5E-8 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 MIM_c12840 9bce6aa88abeab3c5625837815e935f6 350 SUPERFAMILY SSF81345 23 345 4.97E-68 T 12-10-2018 IPR037294 ABC transporter, BtuC-like MIM_c12840 9bce6aa88abeab3c5625837815e935f6 350 Gene3D G3DSA:1.10.3470.10 28 349 1.8E-82 T 12-10-2018 IPR037294 ABC transporter, BtuC-like MIM_c12840 9bce6aa88abeab3c5625837815e935f6 350 Pfam PF01032 FecCD transport family 41 344 4.9E-77 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MIM_c02440 0d53596a0c32f062797a98b50a6ea207 120 Pfam PF04343 Protein of unknown function, DUF488 8 115 9.4E-37 T 12-10-2018 IPR007438 Protein of unknown function DUF488 MIM_c00340 5e3c84b0b8acc6638acbd72cf62a9c7f 306 Gene3D G3DSA:3.40.50.720 14 300 5.1E-92 T 12-10-2018 MIM_c00340 5e3c84b0b8acc6638acbd72cf62a9c7f 306 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 221 237 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MIM_c00340 5e3c84b0b8acc6638acbd72cf62a9c7f 306 SUPERFAMILY SSF52283 5 135 5.86E-23 T 12-10-2018 MIM_c00340 5e3c84b0b8acc6638acbd72cf62a9c7f 306 Gene3D G3DSA:3.40.50.720 97 284 5.1E-92 T 12-10-2018 MIM_c00340 5e3c84b0b8acc6638acbd72cf62a9c7f 306 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 11 303 3.7E-22 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 MIM_c00340 5e3c84b0b8acc6638acbd72cf62a9c7f 306 SUPERFAMILY SSF51735 104 283 1.39E-54 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c00340 5e3c84b0b8acc6638acbd72cf62a9c7f 306 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 282 2.2E-56 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MIM_c00340 5e3c84b0b8acc6638acbd72cf62a9c7f 306 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 192 214 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MIM_c16020 2d5e4902bb4a1e79ce4f1bd0cec15699 454 Gene3D G3DSA:3.40.50.150 150 452 9.8E-82 T 12-10-2018 MIM_c16020 2d5e4902bb4a1e79ce4f1bd0cec15699 454 Pfam PF01189 16S rRNA methyltransferase RsmB/F 252 450 1.0E-47 T 12-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 MIM_c16020 2d5e4902bb4a1e79ce4f1bd0cec15699 454 SUPERFAMILY SSF53335 150 452 8.6E-69 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c16020 2d5e4902bb4a1e79ce4f1bd0cec15699 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 435 452 3.1E-28 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase MIM_c16020 2d5e4902bb4a1e79ce4f1bd0cec15699 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 233 247 3.1E-28 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase MIM_c16020 2d5e4902bb4a1e79ce4f1bd0cec15699 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 262 272 3.1E-28 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase MIM_c16020 2d5e4902bb4a1e79ce4f1bd0cec15699 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 331 343 3.1E-28 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase MIM_c16020 2d5e4902bb4a1e79ce4f1bd0cec15699 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 381 397 3.1E-28 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase MIM_c09370 4973d0b3e9b9764e3d5a05d940dda431 264 Pfam PF14023 Protein of unknown function (DUF4239) 62 253 1.2E-9 T 12-10-2018 IPR025333 Protein of unknown function DUF4239 MIM_c08000 df2b261e1c505b8e8534341e9b9a1df8 133 Pfam PF03817 Malonate transporter MadL subunit 1 116 2.3E-47 T 12-10-2018 IPR004690 Malonate transporter MadL subunit GO:0016020 MIM_c08000 df2b261e1c505b8e8534341e9b9a1df8 133 TIGRFAM TIGR00807 malonate_madL: malonate transporter, MadL subunit 1 116 5.4E-50 T 12-10-2018 IPR004690 Malonate transporter MadL subunit GO:0016020 MIM_c16490 cad37f12dd22fde498ed2a94d7e8fd70 389 Gene3D G3DSA:1.10.8.350 70 243 1.2E-92 T 12-10-2018 MIM_c16490 cad37f12dd22fde498ed2a94d7e8fd70 389 Gene3D G3DSA:1.10.530.10 108 371 1.2E-92 T 12-10-2018 MIM_c16490 cad37f12dd22fde498ed2a94d7e8fd70 389 SUPERFAMILY SSF53955 68 375 1.24E-69 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily MIM_c16490 cad37f12dd22fde498ed2a94d7e8fd70 389 Pfam PF13406 Transglycosylase SLT domain 68 371 1.2E-86 T 12-10-2018 IPR031304 Transglycosylase SLT domain 2 MIM_c16490 cad37f12dd22fde498ed2a94d7e8fd70 389 TIGRFAM TIGR02282 MltB: lytic murein transglycosylase B 71 371 2.0E-100 T 12-10-2018 IPR011757 Lytic transglycosylase MltB MIM_c02770 be128206b721efaeb5a206fdde8a4e4a 104 Pfam PF05433 Glycine zipper 2TM domain 32 69 2.8E-6 T 12-10-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 MIM_c07940 c4280146ab66b042f0341cc070caa15f 223 Pfam PF10620 Phosphoribosyl-dephospho-CoA transferase MdcG 2 208 4.8E-55 T 12-10-2018 IPR017557 Phosphoribosyl-dephospho-CoA transferase GO:0016779 MetaCyc: PWY-5796 MIM_c07940 c4280146ab66b042f0341cc070caa15f 223 TIGRFAM TIGR03135 malonate_mdcG: malonate decarboxylase holo-[acyl-carrier-protein] synthase 2 209 1.1E-48 T 12-10-2018 IPR017557 Phosphoribosyl-dephospho-CoA transferase GO:0016779 MetaCyc: PWY-5796 MIM_c26570 4f7bc4ff8248629e64adf9278cb85b72 128 Pfam PF01850 PIN domain 4 120 4.2E-10 T 12-10-2018 IPR002716 PIN domain MIM_c26570 4f7bc4ff8248629e64adf9278cb85b72 128 SUPERFAMILY SSF88723 1 123 5.61E-18 T 12-10-2018 IPR029060 PIN-like domain superfamily MIM_c26570 4f7bc4ff8248629e64adf9278cb85b72 128 Gene3D G3DSA:3.40.50.1010 1 125 2.2E-8 T 12-10-2018 MIM_c24680 6a23f5856e31ae02c9e6d8ad0faeed03 284 Gene3D G3DSA:3.40.50.12370 2 284 1.7E-64 T 12-10-2018 MIM_c24680 6a23f5856e31ae02c9e6d8ad0faeed03 284 SUPERFAMILY SSF52402 1 157 5.94E-15 T 12-10-2018 MIM_c24680 6a23f5856e31ae02c9e6d8ad0faeed03 284 Pfam PF00582 Universal stress protein family 1 157 3.2E-10 T 12-10-2018 IPR006016 UspA MIM_c24680 6a23f5856e31ae02c9e6d8ad0faeed03 284 Pfam PF00582 Universal stress protein family 227 284 1.6E-11 T 12-10-2018 IPR006016 UspA MIM_c24680 6a23f5856e31ae02c9e6d8ad0faeed03 284 SUPERFAMILY SSF52402 165 284 3.43E-24 T 12-10-2018 MIM_c24680 6a23f5856e31ae02c9e6d8ad0faeed03 284 PRINTS PR01438 Universal stress protein signature 164 182 1.4E-11 T 12-10-2018 IPR006015 Universal stress protein A MIM_c24680 6a23f5856e31ae02c9e6d8ad0faeed03 284 PRINTS PR01438 Universal stress protein signature 244 256 1.4E-11 T 12-10-2018 IPR006015 Universal stress protein A MIM_c24680 6a23f5856e31ae02c9e6d8ad0faeed03 284 PRINTS PR01438 Universal stress protein signature 262 284 1.4E-11 T 12-10-2018 IPR006015 Universal stress protein A MIM_c36550 b376eb69cf7e2c743c8b2b6416880ff7 316 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 7 182 6.0E-45 T 12-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain MIM_c36550 b376eb69cf7e2c743c8b2b6416880ff7 316 SUPERFAMILY SSF90002 226 312 2.75E-7 T 12-10-2018 MIM_c36550 b376eb69cf7e2c743c8b2b6416880ff7 316 Gene3D G3DSA:3.40.50.300 3 199 1.1E-52 T 12-10-2018 MIM_c36550 b376eb69cf7e2c743c8b2b6416880ff7 316 SMART SM00833 226 314 5.3E-12 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MIM_c36550 b376eb69cf7e2c743c8b2b6416880ff7 316 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 226 313 3.5E-11 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MIM_c36550 b376eb69cf7e2c743c8b2b6416880ff7 316 SUPERFAMILY SSF52540 6 191 9.25E-25 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c31960 8696ca2a0b0a8839af9e81ba3b076d1b 322 Pfam PF06527 TniQ 14 140 2.3E-21 T 12-10-2018 IPR009492 TniQ MIM_c22710 1eaf874a58f6d89f522cad3fa1eae2bb 326 Pfam PF00122 E1-E2 ATPase 169 232 1.1E-7 T 12-10-2018 MIM_c34710 1a59fcb13578145131a34044722a353e 133 SUPERFAMILY SSF55298 1 128 1.03E-21 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MIM_c34710 1a59fcb13578145131a34044722a353e 133 Pfam PF01042 Endoribonuclease L-PSP 29 127 8.4E-12 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 MIM_c34710 1a59fcb13578145131a34044722a353e 133 Gene3D G3DSA:3.30.1330.40 1 128 2.9E-21 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MIM_c04940 f8119c0a037989eddbfe9a63b4980c66 263 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 19 46 5.2E-44 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MIM_c04940 f8119c0a037989eddbfe9a63b4980c66 263 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 116 142 5.2E-44 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MIM_c04940 f8119c0a037989eddbfe9a63b4980c66 263 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 167 195 5.2E-44 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MIM_c04940 f8119c0a037989eddbfe9a63b4980c66 263 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 98 116 5.2E-44 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MIM_c04940 f8119c0a037989eddbfe9a63b4980c66 263 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 21 239 3.1E-62 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MIM_c04940 f8119c0a037989eddbfe9a63b4980c66 263 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 9 256 15.919 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MIM_c04940 f8119c0a037989eddbfe9a63b4980c66 263 Pfam PF00902 Sec-independent protein translocase protein (TatC) 23 234 9.3E-63 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MIM_c12380 32fd6dec5b7fd8e5ee5fbe3235e005c1 309 Pfam PF03547 Membrane transport protein 157 301 1.1E-14 T 12-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 MIM_c12380 32fd6dec5b7fd8e5ee5fbe3235e005c1 309 Pfam PF03547 Membrane transport protein 4 145 6.9E-18 T 12-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 MIM_c31090 37f8a977897a9be350132eab9d5942eb 274 Pfam PF00561 alpha/beta hydrolase fold 33 257 1.7E-20 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c31090 37f8a977897a9be350132eab9d5942eb 274 SUPERFAMILY SSF53474 10 270 2.57E-48 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c31090 37f8a977897a9be350132eab9d5942eb 274 Gene3D G3DSA:3.40.50.1820 6 265 4.9E-67 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c02940 1726e059941c35ba5c739d0ec2ff4980 272 Pfam PF09992 Phosphodiester glycosidase 87 266 1.3E-32 T 12-10-2018 IPR018711 Phosphodiester glycosidase MIM_c21560 49ed3ea5d9e72050c486c2011398207b 411 Pfam PF07690 Major Facilitator Superfamily 12 294 1.0E-15 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c21560 49ed3ea5d9e72050c486c2011398207b 411 Gene3D G3DSA:1.20.1250.20 6 393 2.6E-34 T 12-10-2018 MIM_c21560 49ed3ea5d9e72050c486c2011398207b 411 SUPERFAMILY SSF103473 6 397 3.4E-39 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c28840 007cc0495b3f8bcc6e29d8746ca833af 213 Pfam PF01810 LysE type translocator 16 209 1.6E-40 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MIM_c28840 007cc0495b3f8bcc6e29d8746ca833af 213 TIGRFAM TIGR00949 2A76: homoserine/Threonine efflux protein 19 205 7.0E-56 T 12-10-2018 IPR004778 Homoserine/Threonine efflux protein GO:0016021 MIM_c28840 007cc0495b3f8bcc6e29d8746ca833af 213 PIRSF PIRSF006324 1 210 3.7E-44 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MIM_c36710 b8c9eaff0e96547af6e9bbd96e827277 265 Pfam PF13501 Sulfur oxidation protein SoxY 36 144 4.1E-30 T 12-10-2018 IPR032711 Ig-like SoxY domain MIM_c36710 b8c9eaff0e96547af6e9bbd96e827277 265 Gene3D G3DSA:2.60.40.10 162 265 6.0E-24 T 12-10-2018 IPR013783 Immunoglobulin-like fold MIM_c36710 b8c9eaff0e96547af6e9bbd96e827277 265 SUPERFAMILY SSF81296 159 263 1.82E-27 T 12-10-2018 IPR014756 Immunoglobulin E-set MIM_c36710 b8c9eaff0e96547af6e9bbd96e827277 265 Gene3D G3DSA:2.60.40.2470 19 145 5.2E-28 T 12-10-2018 IPR038162 Ig-like SoxY domain superfamily MIM_c36710 b8c9eaff0e96547af6e9bbd96e827277 265 Pfam PF08770 Sulphur oxidation protein SoxZ 171 260 3.5E-28 T 12-10-2018 IPR014880 Sulphur oxidation protein SoxZ MIM_c36710 b8c9eaff0e96547af6e9bbd96e827277 265 TIGRFAM TIGR04557 fuse_rel_SoxYZ: quinoprotein dehydrogenase-associated SoxYZ-like carrier 30 257 1.6E-72 T 12-10-2018 IPR030831 Quinoprotein dehydrogenase-associated SoxYZ-like carrier MIM_c16550 f4b90f6c8082c8041047140e4ffc66f4 322 Gene3D G3DSA:3.90.1200.10 106 316 6.8E-64 T 12-10-2018 MIM_c16550 f4b90f6c8082c8041047140e4ffc66f4 322 TIGRFAM TIGR00938 thrB_alt: homoserine kinase 1 311 2.6E-91 T 12-10-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 MIM_c16550 f4b90f6c8082c8041047140e4ffc66f4 322 SUPERFAMILY SSF56112 5 314 1.6E-65 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily MIM_c16550 f4b90f6c8082c8041047140e4ffc66f4 322 Pfam PF01636 Phosphotransferase enzyme family 27 262 9.4E-30 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase MIM_c16550 f4b90f6c8082c8041047140e4ffc66f4 322 Hamap MF_00301 Homoserine kinase [thrB]. 1 322 138.371 T 12-10-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 MIM_c16550 f4b90f6c8082c8041047140e4ffc66f4 322 Gene3D G3DSA:3.30.200.20 1 102 3.5E-34 T 12-10-2018 MIM_c31330 77b84da9ab2a7f69dbc35b08131f76d2 396 Gene3D G3DSA:3.10.310.10 181 375 9.0E-152 T 12-10-2018 MIM_c31330 77b84da9ab2a7f69dbc35b08131f76d2 396 TIGRFAM TIGR02334 prpF: probable AcnD-accessory protein PrpF 5 396 2.7E-223 T 12-10-2018 IPR012709 2-methyl-aconitate isomerase PrpF GO:0016853|GO:0019629 MIM_c31330 77b84da9ab2a7f69dbc35b08131f76d2 396 SUPERFAMILY SSF54506 190 394 5.96E-76 T 12-10-2018 MIM_c31330 77b84da9ab2a7f69dbc35b08131f76d2 396 Pfam PF04303 PrpF protein 6 392 2.4E-169 T 12-10-2018 IPR007400 PrpF protein MIM_c31330 77b84da9ab2a7f69dbc35b08131f76d2 396 SUPERFAMILY SSF54506 2 182 3.06E-70 T 12-10-2018 MIM_c31330 77b84da9ab2a7f69dbc35b08131f76d2 396 Gene3D G3DSA:3.10.310.10 11 389 9.0E-152 T 12-10-2018 MIM_c36470 a05d60c8e752a22c292cb0ed989cface 167 Pfam PF11158 Protein of unknown function (DUF2938) 12 161 5.1E-46 T 12-10-2018 IPR021329 Protein of unknown function DUF2938 MIM_c19840 ae73438578fd361f16f6c2eb03cb6cce 428 Pfam PF02040 Arsenical pump membrane protein 4 423 1.5E-152 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MIM_c19840 ae73438578fd361f16f6c2eb03cb6cce 428 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 3 426 2.8E-201 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MIM_c19840 ae73438578fd361f16f6c2eb03cb6cce 428 PRINTS PR00758 Arsenical pump membrane protein signature 101 125 1.9E-111 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MIM_c19840 ae73438578fd361f16f6c2eb03cb6cce 428 PRINTS PR00758 Arsenical pump membrane protein signature 177 200 1.9E-111 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MIM_c19840 ae73438578fd361f16f6c2eb03cb6cce 428 PRINTS PR00758 Arsenical pump membrane protein signature 397 421 1.9E-111 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MIM_c19840 ae73438578fd361f16f6c2eb03cb6cce 428 PRINTS PR00758 Arsenical pump membrane protein signature 278 302 1.9E-111 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MIM_c19840 ae73438578fd361f16f6c2eb03cb6cce 428 PRINTS PR00758 Arsenical pump membrane protein signature 323 345 1.9E-111 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MIM_c19840 ae73438578fd361f16f6c2eb03cb6cce 428 PRINTS PR00758 Arsenical pump membrane protein signature 144 168 1.9E-111 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MIM_c19840 ae73438578fd361f16f6c2eb03cb6cce 428 PRINTS PR00758 Arsenical pump membrane protein signature 217 242 1.9E-111 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MIM_c19840 ae73438578fd361f16f6c2eb03cb6cce 428 PRINTS PR00758 Arsenical pump membrane protein signature 364 389 1.9E-111 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MIM_c08130 d1c1fdb64796f996c584431ed1cce436 296 SUPERFAMILY SSF53474 71 295 9.02E-49 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c08130 d1c1fdb64796f996c584431ed1cce436 296 Gene3D G3DSA:3.40.50.1820 58 294 1.8E-72 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c08130 d1c1fdb64796f996c584431ed1cce436 296 Pfam PF01738 Dienelactone hydrolase family 84 292 8.8E-52 T 12-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 MIM_c35000 22f19d6e492265c9fa7bef80a5a66eab 292 Pfam PF02653 Branched-chain amino acid transport system / permease component 4 275 9.3E-48 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c06320 b7961fb9d51b3eae6b93ffd7a8466e25 344 SUPERFAMILY SSF53850 36 285 2.08E-43 T 12-10-2018 MIM_c06320 b7961fb9d51b3eae6b93ffd7a8466e25 344 SMART SM00062 39 266 0.0049 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c06320 b7961fb9d51b3eae6b93ffd7a8466e25 344 Pfam PF13379 NMT1-like family 38 265 8.1E-26 T 12-10-2018 MIM_c06320 b7961fb9d51b3eae6b93ffd7a8466e25 344 Gene3D G3DSA:3.40.190.10 119 229 1.3E-112 T 12-10-2018 MIM_c06320 b7961fb9d51b3eae6b93ffd7a8466e25 344 Gene3D G3DSA:3.40.190.10 40 338 1.3E-112 T 12-10-2018 MIM_c21920 48c4da1e21a344c952cbefb3773f6ef6 137 Pfam PF03610 PTS system fructose IIA component 6 112 2.3E-12 T 12-10-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 MIM_c21920 48c4da1e21a344c952cbefb3773f6ef6 137 SUPERFAMILY SSF53062 1 133 7.06E-25 T 12-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 MIM_c21920 48c4da1e21a344c952cbefb3773f6ef6 137 Gene3D G3DSA:3.40.50.510 1 137 6.4E-28 T 12-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 MIM_c26410 004a24b6a40f19f2cbbb6e380f96e33f 342 SUPERFAMILY SSF161098 89 324 3.27E-20 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c26410 004a24b6a40f19f2cbbb6e380f96e33f 342 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 339 2.6E-45 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c40170 68fc46e2511b6dabf1a505add4cc2d2e 450 SUPERFAMILY SSF103378 3 432 4.84E-119 T 12-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 MIM_c40170 68fc46e2511b6dabf1a505add4cc2d2e 450 Gene3D G3DSA:3.30.1330.120 269 400 1.1E-106 T 12-10-2018 MIM_c40170 68fc46e2511b6dabf1a505add4cc2d2e 450 Pfam PF03972 MmgE/PrpD family 8 429 4.2E-135 T 12-10-2018 IPR005656 MmgE/PrpD GO:0016829 MIM_c40170 68fc46e2511b6dabf1a505add4cc2d2e 450 Gene3D G3DSA:1.10.4100.10 26 416 1.1E-106 T 12-10-2018 MIM_c09280 27091bb92f67c3815bceee71272e2d25 324 Gene3D G3DSA:3.90.79.10 2 125 4.0E-34 T 12-10-2018 MIM_c09280 27091bb92f67c3815bceee71272e2d25 324 Pfam PF02581 Thiamine monophosphate synthase 138 321 1.2E-37 T 12-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MIM_c09280 27091bb92f67c3815bceee71272e2d25 324 SUPERFAMILY SSF55811 4 119 8.26E-32 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MIM_c09280 27091bb92f67c3815bceee71272e2d25 324 PRINTS PR00502 NUDIX hydrolase family signature 38 52 4.3E-8 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MIM_c09280 27091bb92f67c3815bceee71272e2d25 324 PRINTS PR00502 NUDIX hydrolase family signature 52 67 4.3E-8 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MIM_c09280 27091bb92f67c3815bceee71272e2d25 324 SUPERFAMILY SSF51391 121 322 3.66E-42 T 12-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MIM_c09280 27091bb92f67c3815bceee71272e2d25 324 Pfam PF00293 NUDIX domain 10 132 2.0E-20 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MIM_c09280 27091bb92f67c3815bceee71272e2d25 324 ProSitePatterns PS00893 Nudix box signature. 43 64 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MIM_c09280 27091bb92f67c3815bceee71272e2d25 324 Gene3D G3DSA:3.20.20.70 135 324 1.7E-43 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c20160 4d88f4a23c7985959f4a497c71e5adb4 136 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 55 120 8.3E-23 T 12-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal MIM_c20160 4d88f4a23c7985959f4a497c71e5adb4 136 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 18 54 6.3E-16 T 12-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal MIM_c20160 4d88f4a23c7985959f4a497c71e5adb4 136 Gene3D G3DSA:1.10.12.20 10 57 2.7E-6 T 12-10-2018 MIM_c20160 4d88f4a23c7985959f4a497c71e5adb4 136 SUPERFAMILY SSF50249 6 128 6.34E-40 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold MIM_c06880 ce277ebd681e4fd4fab39245acf52dda 266 Pfam PF01061 ABC-2 type transporter 21 226 2.2E-26 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MIM_c19720 b6628561f70ea191591cef20f46f8298 289 SUPERFAMILY SSF46785 1 109 2.63E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c19720 b6628561f70ea191591cef20f46f8298 289 SUPERFAMILY SSF53850 89 272 2.85E-31 T 12-10-2018 MIM_c19720 b6628561f70ea191591cef20f46f8298 289 Pfam PF03466 LysR substrate binding domain 88 272 2.8E-30 T 12-10-2018 IPR005119 LysR, substrate-binding MIM_c19720 b6628561f70ea191591cef20f46f8298 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 4.3E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MIM_c19720 b6628561f70ea191591cef20f46f8298 289 Gene3D G3DSA:3.40.190.10 164 262 2.6E-30 T 12-10-2018 MIM_c19720 b6628561f70ea191591cef20f46f8298 289 Gene3D G3DSA:3.40.190.10 89 273 2.6E-30 T 12-10-2018 MIM_c19720 b6628561f70ea191591cef20f46f8298 289 Gene3D G3DSA:1.10.10.10 1 82 3.3E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c06190 4f98c46e35bc9d425d78b77ca86a118e 118 Gene3D G3DSA:2.60.40.420 19 115 3.7E-13 T 12-10-2018 IPR008972 Cupredoxin MIM_c06190 4f98c46e35bc9d425d78b77ca86a118e 118 Pfam PF13473 Cupredoxin-like domain 13 114 1.0E-24 T 12-10-2018 IPR028096 EfeO-type cupredoxin-like domain MIM_c06190 4f98c46e35bc9d425d78b77ca86a118e 118 SUPERFAMILY SSF49503 15 115 9.52E-17 T 12-10-2018 IPR008972 Cupredoxin MIM_c37450 084e1f0aee4430271340298c485f65b7 293 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 71 84 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site MIM_c37450 084e1f0aee4430271340298c485f65b7 293 SUPERFAMILY SSF53850 20 270 1.57E-59 T 12-10-2018 MIM_c37450 084e1f0aee4430271340298c485f65b7 293 Gene3D G3DSA:3.40.190.10 135 227 1.4E-63 T 12-10-2018 MIM_c37450 084e1f0aee4430271340298c485f65b7 293 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 48 268 1.6E-55 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c37450 084e1f0aee4430271340298c485f65b7 293 Gene3D G3DSA:3.40.190.10 37 269 1.4E-63 T 12-10-2018 MIM_c37450 084e1f0aee4430271340298c485f65b7 293 SMART SM00062 47 270 1.4E-58 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c03020 567691ef2045d22ac12f5f8b8de01e39 582 Pfam PF06097 Bacterial protein of unknown function (DUF945) 10 483 2.8E-64 T 12-10-2018 IPR010352 Protein of unknown function DUF945 MIM_c03520 7cc7c95f963c0c8b3c0211758663b912 276 Pfam PF05036 Sporulation related domain 204 276 5.7E-13 T 12-10-2018 IPR007730 Sporulation-like domain GO:0042834 MIM_c03520 7cc7c95f963c0c8b3c0211758663b912 276 Gene3D G3DSA:3.30.70.1070 198 276 1.1E-14 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 MIM_c03520 7cc7c95f963c0c8b3c0211758663b912 276 SUPERFAMILY SSF110997 202 275 3.01E-13 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 MIM_c10680 e746f3f69fd131859629a562e8bd0717 233 Pfam PF09669 Phage regulatory protein Rha (Phage_pRha) 16 99 1.6E-12 T 12-10-2018 IPR014054 Bacteriophage regulatory protein, Rha family MIM_c00510 37f2b927c73779159563a5cf4b5224db 261 SUPERFAMILY SSF51621 1 256 1.82E-61 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MIM_c00510 37f2b927c73779159563a5cf4b5224db 261 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 28 210 9.9E-32 T 12-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 MIM_c00510 37f2b927c73779159563a5cf4b5224db 261 Gene3D G3DSA:3.20.20.60 1 260 7.0E-73 T 12-10-2018 MIM_c25430 9ed2aebed5ec9aa59039506e149d1d92 276 SUPERFAMILY SSF53474 22 272 1.77E-35 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c25430 9ed2aebed5ec9aa59039506e149d1d92 276 Gene3D G3DSA:3.40.50.1820 22 271 3.6E-32 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c25430 9ed2aebed5ec9aa59039506e149d1d92 276 Pfam PF12697 Alpha/beta hydrolase family 42 266 3.3E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c14030 95da4654db98f8edfe87f03c4598479b 328 Pfam PF01758 Sodium Bile acid symporter family 42 217 3.3E-15 T 12-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 MIM_c14030 95da4654db98f8edfe87f03c4598479b 328 Gene3D G3DSA:1.20.1530.20 1 312 2.6E-31 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily MIM_c08320 2c2887f8efa548a7e5fc541fef04f7e9 263 SMART SM00062 36 255 1.6E-41 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c08320 2c2887f8efa548a7e5fc541fef04f7e9 263 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 37 253 1.9E-48 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c08320 2c2887f8efa548a7e5fc541fef04f7e9 263 Gene3D G3DSA:3.40.190.10 123 213 2.8E-55 T 12-10-2018 MIM_c08320 2c2887f8efa548a7e5fc541fef04f7e9 263 Gene3D G3DSA:3.40.190.10 31 248 2.8E-55 T 12-10-2018 MIM_c08320 2c2887f8efa548a7e5fc541fef04f7e9 263 SMART SM00079 36 252 0.0024 T 12-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 MIM_c08320 2c2887f8efa548a7e5fc541fef04f7e9 263 SUPERFAMILY SSF53850 8 254 6.21E-57 T 12-10-2018 MIM_c33380 056a9cfbadfd412bf6941ad20aa07045 87 SUPERFAMILY SSF53098 2 78 7.02E-5 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily MIM_c00880 3f8ac198a66746d3620538ed82e5c740 266 SUPERFAMILY SSF51735 3 260 5.8E-24 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily MIM_c00880 3f8ac198a66746d3620538ed82e5c740 266 Gene3D G3DSA:3.40.50.720 2 262 1.9E-15 T 12-10-2018 MIM_c39570 835ec7a29253b21bfe992e918b7f0add 301 Pfam PF05035 2-keto-3-deoxy-galactonokinase 9 295 3.4E-92 T 12-10-2018 IPR007729 2-keto-3-deoxy-galactonokinase GO:0008671|GO:0034194 KEGG: 00052+2.7.1.58|MetaCyc: PWY-7130 MIM_c39570 835ec7a29253b21bfe992e918b7f0add 301 Gene3D G3DSA:3.30.420.300 6 109 5.6E-89 T 12-10-2018 MIM_c39570 835ec7a29253b21bfe992e918b7f0add 301 Gene3D G3DSA:3.30.420.310 80 285 5.6E-89 T 12-10-2018 MIM_c39570 835ec7a29253b21bfe992e918b7f0add 301 SUPERFAMILY SSF53067 4 167 2.54E-5 T 12-10-2018 MIM_c34350 ee65131848eff5661bee55cbc5c69072 270 Gene3D G3DSA:3.40.720.10 3 269 4.1E-33 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 MIM_c34350 ee65131848eff5661bee55cbc5c69072 270 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 5 210 1.8E-15 T 12-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 MIM_c34350 ee65131848eff5661bee55cbc5c69072 270 SUPERFAMILY SSF53649 2 255 3.27E-48 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 MIM_c04480 6c7db8db0fb8c33d3993e22e6cb4d218 267 Gene3D G3DSA:3.90.550.10 2 247 6.6E-22 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MIM_c04480 6c7db8db0fb8c33d3993e22e6cb4d218 267 Pfam PF00535 Glycosyl transferase family 2 16 132 1.1E-16 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MIM_c04480 6c7db8db0fb8c33d3993e22e6cb4d218 267 SUPERFAMILY SSF53448 12 148 2.25E-23 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MIM_c38180 2e52b016eb8f4e04e77a24b021fc62ea 216 Gene3D G3DSA:1.10.3720.10 2 215 2.3E-52 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c38180 2e52b016eb8f4e04e77a24b021fc62ea 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 9 106 9.5E-32 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c38180 2e52b016eb8f4e04e77a24b021fc62ea 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 211 4.4E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c38180 2e52b016eb8f4e04e77a24b021fc62ea 216 SUPERFAMILY SSF161098 11 197 1.7E-44 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c24420 528a2eb034bf5feb019dcbe971296bb2 116 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 111 8.8E-8 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MIM_c24420 528a2eb034bf5feb019dcbe971296bb2 116 SUPERFAMILY SSF54593 6 112 4.97E-26 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c24420 528a2eb034bf5feb019dcbe971296bb2 116 Gene3D G3DSA:3.10.180.10 14 115 6.3E-29 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c03160 ed07082b2f40d6b71d93cd9807a08d92 170 SUPERFAMILY SSF69118 21 161 2.16E-19 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c03160 ed07082b2f40d6b71d93cd9807a08d92 170 Gene3D G3DSA:1.20.1290.10 50 168 1.5E-11 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MIM_c40410 6b545a9addbfe1c20ad6ac8f42b2efc1 308 PIRSF PIRSF028561 1 308 4.4E-92 T 12-10-2018 IPR014548 Predicted acyltransferase MIM_c40410 6b545a9addbfe1c20ad6ac8f42b2efc1 308 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 117 305 9.3E-13 T 12-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 MIM_c27320 bc1f5589abf008f0c439c3431035d0e9 191 Gene3D G3DSA:3.30.1380.10 74 191 1.9E-11 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MIM_c27320 bc1f5589abf008f0c439c3431035d0e9 191 SUPERFAMILY SSF55166 75 191 4.71E-31 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MIM_c27320 bc1f5589abf008f0c439c3431035d0e9 191 Pfam PF05951 Bacterial protein of unknown function (DUF882) 45 191 2.1E-53 T 12-10-2018 IPR010275 Protein of unknown function DUF882 MIM_c21400 068b5ee8c65d96d1af9c90481d7ad58b 259 SUPERFAMILY SSF53098 4 223 2.1E-40 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily MIM_c21400 068b5ee8c65d96d1af9c90481d7ad58b 259 Gene3D G3DSA:3.30.420.10 5 214 3.0E-19 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MIM_c21400 068b5ee8c65d96d1af9c90481d7ad58b 259 Pfam PF10108 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB 47 256 2.5E-90 T 12-10-2018 IPR019288 Predicted 3'-5' exonuclease, PolB-like MIM_c39800 61f59b25bda5f9a511fd76e00ba0c373 341 Pfam PF02653 Branched-chain amino acid transport system / permease component 55 331 2.5E-38 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c21170 d49da28e928e1b4f3f07b9d0216fac68 546 Pfam PF00361 Proton-conducting membrane transporter 137 445 1.2E-35 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c03320 332db916330fcd368190129928408f90 132 SUPERFAMILY SSF46955 6 118 9.16E-23 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily MIM_c03320 332db916330fcd368190129928408f90 132 Gene3D G3DSA:1.10.1660.10 1 117 8.4E-24 T 12-10-2018 MIM_c03320 332db916330fcd368190129928408f90 132 SMART SM00422 6 73 4.8E-15 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MIM_c03320 332db916330fcd368190129928408f90 132 Pfam PF13411 MerR HTH family regulatory protein 7 66 4.1E-12 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MIM_c33560 e13dd893db807206869f92764f393822 271 Pfam PF01925 Sulfite exporter TauE/SafE 13 265 5.0E-51 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MIM_c22100 e7e8b8ff4880005c673c74e4fa304f62 286 Hamap MF_01384 Urease accessory protein UreD [ureD]. 10 270 25.82 T 12-10-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 MIM_c22100 e7e8b8ff4880005c673c74e4fa304f62 286 Pfam PF01774 UreD urease accessory protein 54 260 2.3E-40 T 12-10-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 MIM_c12850 f222af0a89b8018ef41c6d1cc71eadc3 337 Pfam PF01032 FecCD transport family 21 334 3.2E-81 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MIM_c12850 f222af0a89b8018ef41c6d1cc71eadc3 337 Gene3D G3DSA:1.10.3470.10 9 337 5.2E-87 T 12-10-2018 IPR037294 ABC transporter, BtuC-like MIM_c12850 f222af0a89b8018ef41c6d1cc71eadc3 337 SUPERFAMILY SSF81345 8 334 2.48E-71 T 12-10-2018 IPR037294 ABC transporter, BtuC-like MIM_c40000 2adf196c7c0a5e5ce9e007d9b787d525 131 SUPERFAMILY SSF54593 3 130 3.89E-30 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c40000 2adf196c7c0a5e5ce9e007d9b787d525 131 Gene3D G3DSA:3.10.180.10 2 129 1.9E-30 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c40000 2adf196c7c0a5e5ce9e007d9b787d525 131 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 123 3.7E-11 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MIM_c37460 cf7c2082c13283eccd3e419ba0399e3b 231 SUPERFAMILY SSF161098 16 211 1.53E-35 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c37460 cf7c2082c13283eccd3e419ba0399e3b 231 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 120 2.1E-16 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c37460 cf7c2082c13283eccd3e419ba0399e3b 231 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 42 224 1.3E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c37460 cf7c2082c13283eccd3e419ba0399e3b 231 Gene3D G3DSA:1.10.3720.10 11 227 5.2E-43 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c14880 65d555f79b73e0e3da5939aa4c48b5d0 344 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 12 322 5.7E-93 T 12-10-2018 IPR016833 Putative sodium bile acid cotransporter MIM_c14880 65d555f79b73e0e3da5939aa4c48b5d0 344 Gene3D G3DSA:1.20.1530.20 10 329 1.1E-31 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily MIM_c14880 65d555f79b73e0e3da5939aa4c48b5d0 344 PIRSF PIRSF026166 1 340 9.3E-128 T 12-10-2018 IPR016833 Putative sodium bile acid cotransporter MIM_c37110 c4f1775f99573c1b88798e45d6f6f6e8 78 Gene3D G3DSA:3.40.190.150 3 78 3.2E-12 T 12-10-2018 MIM_c37110 c4f1775f99573c1b88798e45d6f6f6e8 78 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 19 75 6.9E-5 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c11510 dcd5997af876db78088793286bdaf714 295 Hamap MF_00361 NAD kinase [nadK]. 4 288 32.03 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 MIM_c11510 dcd5997af876db78088793286bdaf714 295 SUPERFAMILY SSF111331 5 290 3.66E-85 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily MIM_c11510 dcd5997af876db78088793286bdaf714 295 Gene3D G3DSA:2.60.200.30 126 265 9.5E-89 T 12-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 MIM_c11510 dcd5997af876db78088793286bdaf714 295 Pfam PF01513 ATP-NAD kinase 49 271 6.1E-57 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 MIM_c11510 dcd5997af876db78088793286bdaf714 295 Gene3D G3DSA:3.40.50.10330 23 288 9.5E-89 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 MIM_c00760 89ac12fb733f4d0b67906f2c56c8431e 89 PIRSF PIRSF004669 1 89 1.6E-21 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MIM_c00760 89ac12fb733f4d0b67906f2c56c8431e 89 Pfam PF01313 Bacterial export proteins, family 3 6 76 4.0E-21 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MIM_c00760 89ac12fb733f4d0b67906f2c56c8431e 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 5.7E-18 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MIM_c00760 89ac12fb733f4d0b67906f2c56c8431e 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 5.7E-18 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MIM_c00760 89ac12fb733f4d0b67906f2c56c8431e 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 5.7E-18 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MIM_c08920 a0909af64b1e832119bb8227d54905f0 130 Pfam PF07681 DoxX 10 87 2.5E-11 T 12-10-2018 IPR032808 DoxX family MIM_c19700 c4d469b65ebfdab89bae24a573426edc 327 PIRSF PIRSF017082 1 325 3.4E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c19700 c4d469b65ebfdab89bae24a573426edc 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 321 9.2E-73 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c19700 c4d469b65ebfdab89bae24a573426edc 327 SUPERFAMILY SSF53850 105 282 5.16E-9 T 12-10-2018 MIM_c19700 c4d469b65ebfdab89bae24a573426edc 327 Gene3D G3DSA:3.40.190.10 127 250 2.2E-107 T 12-10-2018 MIM_c19700 c4d469b65ebfdab89bae24a573426edc 327 Gene3D G3DSA:3.40.190.150 27 310 2.2E-107 T 12-10-2018 MIM_c16410 5afda5da029cae8dbe5efb6b132fa617 423 Pfam PF16491 CAAX prenyl protease N-terminal, five membrane helices 28 206 2.6E-54 T 12-10-2018 IPR032456 CAAX prenyl protease 1, N-terminal KEGG: 00900+3.4.24.84 MIM_c16410 5afda5da029cae8dbe5efb6b132fa617 423 Gene3D G3DSA:3.30.2010.10 205 286 1.7E-31 T 12-10-2018 MIM_c16410 5afda5da029cae8dbe5efb6b132fa617 423 Pfam PF01435 Peptidase family M48 209 418 2.5E-40 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 MIM_c16670 4472a9572c8dd579c36817de48469726 497 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 5 483 39.992 T 12-10-2018 IPR003846 Uncharacterised protein family UPF0061 MIM_c16670 4472a9572c8dd579c36817de48469726 497 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 5 467 1.5E-141 T 12-10-2018 IPR003846 Uncharacterised protein family UPF0061 MIM_c15200 402502336e7ba0521bdd22187fabb966 293 Pfam PF01522 Polysaccharide deacetylase 57 224 3.7E-30 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MIM_c15200 402502336e7ba0521bdd22187fabb966 293 Gene3D G3DSA:3.20.20.370 2 255 5.2E-68 T 12-10-2018 MIM_c15200 402502336e7ba0521bdd22187fabb966 293 SUPERFAMILY SSF88713 23 250 4.2E-41 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MIM_c06930 c8164deb556fd82c4ef3767bd0aa8531 702 Pfam PF01757 Acyltransferase family 10 356 1.3E-27 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 MIM_c17170 40185bfd7c16dbe49b540262de85a759 169 SUPERFAMILY SSF55729 3 143 2.33E-24 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c17170 40185bfd7c16dbe49b540262de85a759 169 Gene3D G3DSA:3.40.630.30 2 167 5.0E-46 T 12-10-2018 MIM_c17170 40185bfd7c16dbe49b540262de85a759 169 Pfam PF13508 Acetyltransferase (GNAT) domain 52 130 1.2E-9 T 12-10-2018 IPR000182 GNAT domain MIM_c07980 b375d242a7d9e988a2f352a212f0721f 551 TIGRFAM TIGR01110 mdcA: malonate decarboxylase, alpha subunit 10 551 1.2E-293 T 12-10-2018 IPR005777 Acetyl-S-ACP:malonate ACP transferase MetaCyc: PWY-5794|MetaCyc: PWY-6060 MIM_c07980 b375d242a7d9e988a2f352a212f0721f 551 SUPERFAMILY SSF100950 44 277 1.02E-32 T 12-10-2018 IPR037171 NagB/RpiA transferase-like MIM_c07980 b375d242a7d9e988a2f352a212f0721f 551 Gene3D G3DSA:3.40.1080.10 38 245 2.3E-16 T 12-10-2018 MIM_c07980 b375d242a7d9e988a2f352a212f0721f 551 Pfam PF16957 Malonate decarboxylase, alpha subunit, transporter 10 551 2.0E-294 T 12-10-2018 IPR005777 Acetyl-S-ACP:malonate ACP transferase MetaCyc: PWY-5794|MetaCyc: PWY-6060 MIM_c07980 b375d242a7d9e988a2f352a212f0721f 551 SUPERFAMILY SSF100950 226 495 5.02E-21 T 12-10-2018 IPR037171 NagB/RpiA transferase-like MIM_c22220 c0af2f22ce536c4d1215a7b3a8f6d64e 223 Hamap MF_02089 Epoxyqueuosine reductase QueH [queH]. 21 197 32.934 T 12-10-2018 IPR003828 Epoxyqueuosine reductase QueH MetaCyc: PWY-6700 MIM_c22220 c0af2f22ce536c4d1215a7b3a8f6d64e 223 Pfam PF02677 Uncharacterized BCR, COG1636 21 195 3.2E-64 T 12-10-2018 IPR003828 Epoxyqueuosine reductase QueH MetaCyc: PWY-6700 MIM_c13140 42c4352fe48a35402c4bc47fad8d05ba 123 SUPERFAMILY SSF54593 8 117 5.23E-14 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c13140 42c4352fe48a35402c4bc47fad8d05ba 123 Gene3D G3DSA:3.10.180.10 1 121 4.5E-23 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c37680 e3fc48601ddd2f4c1e71e842c505c17f 740 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 60 192 5.0E-23 T 12-10-2018 IPR006342 Methyltransferase FkbM MIM_c37680 e3fc48601ddd2f4c1e71e842c505c17f 740 Pfam PF05050 Methyltransferase FkbM domain 63 212 1.9E-14 T 12-10-2018 IPR006342 Methyltransferase FkbM MIM_c37680 e3fc48601ddd2f4c1e71e842c505c17f 740 Gene3D G3DSA:3.40.50.150 48 225 3.0E-34 T 12-10-2018 MIM_c37680 e3fc48601ddd2f4c1e71e842c505c17f 740 SUPERFAMILY SSF53335 25 212 3.28E-41 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c04070 64d13de770d732dc7f5b363ccc55feb4 184 Pfam PF01292 Prokaryotic cytochrome b561 12 181 8.0E-27 T 12-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 MIM_c04070 64d13de770d732dc7f5b363ccc55feb4 184 SUPERFAMILY SSF81342 11 181 2.75E-35 T 12-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 MIM_c36460 829209d6fa698241f33ed4051e28760d 178 Gene3D G3DSA:2.40.128.270 60 173 4.8E-26 T 12-10-2018 IPR038670 HslJ-like superfamily MIM_c36460 829209d6fa698241f33ed4051e28760d 178 Pfam PF03724 META domain 63 169 1.7E-26 T 12-10-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ MIM_c31230 5bc58aebfb9bcc8068586e72700f9b36 111 Gene3D G3DSA:1.10.3730.20 2 111 3.0E-34 T 12-10-2018 MIM_c31230 5bc58aebfb9bcc8068586e72700f9b36 111 Pfam PF00893 Small Multidrug Resistance protein 5 95 4.4E-25 T 12-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 MIM_c31230 5bc58aebfb9bcc8068586e72700f9b36 111 SUPERFAMILY SSF103481 7 107 4.97E-18 T 12-10-2018 MIM_c16130 274ce00d24860bd0aecebd04a581fb08 150 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 17 145 2.2E-47 T 12-10-2018 IPR003791 Protein of unknown function UPF0178 MIM_c16130 274ce00d24860bd0aecebd04a581fb08 150 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 147 31.379 T 12-10-2018 IPR003791 Protein of unknown function UPF0178 MIM_c01850 0cbf449fe7807a1bdafaf131d8b9dad3 462 Pfam PF05977 Transmembrane secretion effector 34 441 9.1E-31 T 12-10-2018 IPR010290 Transmembrane secretion effector MIM_c01850 0cbf449fe7807a1bdafaf131d8b9dad3 462 SUPERFAMILY SSF103473 41 443 1.19E-37 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c01850 0cbf449fe7807a1bdafaf131d8b9dad3 462 Gene3D G3DSA:1.20.1250.20 39 443 6.1E-31 T 12-10-2018 MIM_c34330 c19ff673580bef3ea8704354ebb74113 271 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 266 1.9E-10 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c34330 c19ff673580bef3ea8704354ebb74113 271 SUPERFAMILY SSF161098 14 270 1.68E-43 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c34330 c19ff673580bef3ea8704354ebb74113 271 Gene3D G3DSA:1.10.3720.10 11 263 5.8E-37 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c01050 0d19519b9b64fcb0f737868e41bafc21 162 Gene3D G3DSA:3.30.1330.80 7 127 5.3E-6 T 12-10-2018 MIM_c01050 0d19519b9b64fcb0f737868e41bafc21 162 SUPERFAMILY SSF117856 11 120 3.4E-11 T 12-10-2018 MIM_c12800 0474a757ebeb1e11f689d201dc009f88 415 Gene3D G3DSA:3.40.50.2000 61 207 1.8E-16 T 12-10-2018 MIM_c12800 0474a757ebeb1e11f689d201dc009f88 415 SUPERFAMILY SSF53756 68 371 3.09E-47 T 12-10-2018 MIM_c12800 0474a757ebeb1e11f689d201dc009f88 415 Gene3D G3DSA:3.40.50.2000 233 383 3.9E-22 T 12-10-2018 MIM_c12800 0474a757ebeb1e11f689d201dc009f88 415 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 137 359 3.3E-17 T 12-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 MIM_c14230 2a723102b33a173e54e44ef637e0a750 141 Pfam PF00583 Acetyltransferase (GNAT) family 25 125 1.5E-16 T 12-10-2018 IPR000182 GNAT domain MIM_c14230 2a723102b33a173e54e44ef637e0a750 141 Gene3D G3DSA:3.40.630.30 3 141 3.2E-41 T 12-10-2018 MIM_c14230 2a723102b33a173e54e44ef637e0a750 141 SUPERFAMILY SSF55729 1 130 1.74E-29 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c37900 e7dc53d8117a569fa95331550f3756b4 374 Gene3D G3DSA:3.50.50.60 7 355 2.8E-95 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c37900 e7dc53d8117a569fa95331550f3756b4 374 SUPERFAMILY SSF51905 6 368 4.53E-56 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c37900 e7dc53d8117a569fa95331550f3756b4 374 Pfam PF01266 FAD dependent oxidoreductase 7 349 9.2E-64 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MIM_c37900 e7dc53d8117a569fa95331550f3756b4 374 Gene3D G3DSA:3.30.9.10 86 312 2.8E-95 T 12-10-2018 MIM_c37900 e7dc53d8117a569fa95331550f3756b4 374 SUPERFAMILY SSF54373 228 310 1.83E-6 T 12-10-2018 MIM_c38130 8cb98666c3792b1f1d90282f0f582615 1206 Pfam PF01968 Hydantoinase/oxoprolinase 204 491 4.1E-112 T 12-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 MIM_c38130 8cb98666c3792b1f1d90282f0f582615 1206 Pfam PF02538 Hydantoinase B/oxoprolinase 690 1204 1.4E-206 T 12-10-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 MIM_c38130 8cb98666c3792b1f1d90282f0f582615 1206 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 6 185 3.1E-60 T 12-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 MIM_c23950 b08afbaf6b4150c043027974087afbf2 60 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 16.184 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c23950 b08afbaf6b4150c043027974087afbf2 60 Pfam PF01783 Ribosomal L32p protein family 2 55 1.0E-16 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c23950 b08afbaf6b4150c043027974087afbf2 60 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 1.2E-18 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c23950 b08afbaf6b4150c043027974087afbf2 60 SUPERFAMILY SSF57829 2 55 1.28E-16 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 MIM_c15890 ac371ac2b988b727ab8bdfb0ecce904b 425 Pfam PF04403 Paraquat-inducible protein A 45 193 2.6E-40 T 12-10-2018 IPR007498 Intermembrane transport protein PqiA-like MIM_c15890 ac371ac2b988b727ab8bdfb0ecce904b 425 Pfam PF04403 Paraquat-inducible protein A 250 406 8.9E-48 T 12-10-2018 IPR007498 Intermembrane transport protein PqiA-like MIM_c21860 c520ca65c7bb77faa7aefeb9b26ea877 94 Pfam PF04380 Membrane fusogenic activity 1 75 1.0E-24 T 12-10-2018 IPR007475 Membrane fusogenic activity MIM_c17910 9163d0dc6b3259cc1c15867a1f5018d4 384 SUPERFAMILY SSF50998 33 373 4.6E-57 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MIM_c17910 9163d0dc6b3259cc1c15867a1f5018d4 384 Pfam PF13360 PQQ-like domain 78 308 6.9E-41 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat MIM_c17910 9163d0dc6b3259cc1c15867a1f5018d4 384 SMART SM00564 320 352 7.5 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c17910 9163d0dc6b3259cc1c15867a1f5018d4 384 SMART SM00564 143 175 0.072 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c17910 9163d0dc6b3259cc1c15867a1f5018d4 384 SMART SM00564 65 96 81.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c17910 9163d0dc6b3259cc1c15867a1f5018d4 384 SMART SM00564 189 220 35.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c17910 9163d0dc6b3259cc1c15867a1f5018d4 384 SMART SM00564 104 135 0.037 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c17910 9163d0dc6b3259cc1c15867a1f5018d4 384 SMART SM00564 240 273 660.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MIM_c17910 9163d0dc6b3259cc1c15867a1f5018d4 384 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 12 381 8.4E-99 T 12-10-2018 IPR017687 Outer membrane protein assembly factor BamB MIM_c17910 9163d0dc6b3259cc1c15867a1f5018d4 384 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 6 383 32.071 T 12-10-2018 IPR017687 Outer membrane protein assembly factor BamB MIM_c17910 9163d0dc6b3259cc1c15867a1f5018d4 384 Gene3D G3DSA:2.130.10.10 27 382 2.1E-71 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MIM_c39300 97fb3025abce2fe38bc59e16b65de426 295 Pfam PF02653 Branched-chain amino acid transport system / permease component 16 283 3.2E-39 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c07100 ff12208c21640543dd740538c5026e5e 421 Pfam PF02481 DNA recombination-mediator protein A 75 283 3.0E-73 T 12-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 MIM_c07100 ff12208c21640543dd740538c5026e5e 421 Gene3D G3DSA:3.40.50.450 1 295 6.2E-106 T 12-10-2018 MIM_c07100 ff12208c21640543dd740538c5026e5e 421 SUPERFAMILY SSF47781 5 56 1.53E-5 T 12-10-2018 IPR010994 RuvA domain 2-like MIM_c07100 ff12208c21640543dd740538c5026e5e 421 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 74 292 3.0E-74 T 12-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 MIM_c07100 ff12208c21640543dd740538c5026e5e 421 SUPERFAMILY SSF102405 84 292 1.31E-42 T 12-10-2018 MIM_c07100 ff12208c21640543dd740538c5026e5e 421 Gene3D G3DSA:1.10.10.10 341 414 5.1E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c13110 75b09d701f24918fddef7e7f3b2ad99c 399 Pfam PF11062 Protein of unknown function (DUF2863) 3 392 1.6E-143 T 12-10-2018 IPR021292 Protein of unknown function DUF2863 MIM_c28050 9fecbfb2c2d97f7e8f0a5ba6ddb0883c 306 Gene3D G3DSA:3.40.50.300 87 218 2.9E-29 T 12-10-2018 MIM_c28050 9fecbfb2c2d97f7e8f0a5ba6ddb0883c 306 SUPERFAMILY SSF52540 87 217 4.25E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c19270 7c92d1f9fd417d9c20fc6f6fe1d8a569 167 Gene3D G3DSA:1.10.10.10 4 151 3.3E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c19270 7c92d1f9fd417d9c20fc6f6fe1d8a569 167 SUPERFAMILY SSF46785 15 151 2.03E-29 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c19270 7c92d1f9fd417d9c20fc6f6fe1d8a569 167 SMART SM00347 33 133 2.4E-22 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c19270 7c92d1f9fd417d9c20fc6f6fe1d8a569 167 Pfam PF12802 MarR family 39 96 4.1E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c19270 7c92d1f9fd417d9c20fc6f6fe1d8a569 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 6.5E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c19270 7c92d1f9fd417d9c20fc6f6fe1d8a569 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 6.5E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c19270 7c92d1f9fd417d9c20fc6f6fe1d8a569 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 6.5E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MIM_c36920 174b862d291a83e3f2c2fe32010d5389 162 Gene3D G3DSA:3.10.129.10 1 152 1.2E-56 T 12-10-2018 MIM_c36920 174b862d291a83e3f2c2fe32010d5389 162 Pfam PF03061 Thioesterase superfamily 23 95 3.0E-17 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MIM_c36920 174b862d291a83e3f2c2fe32010d5389 162 SUPERFAMILY SSF54637 3 155 1.34E-44 T 12-10-2018 IPR029069 HotDog domain superfamily MIM_c21290 ee4c5b79e1e67d49eec31d63e9a4fd78 260 Gene3D G3DSA:3.40.50.150 17 251 1.6E-39 T 12-10-2018 MIM_c21290 ee4c5b79e1e67d49eec31d63e9a4fd78 260 SUPERFAMILY SSF53335 11 237 6.67E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c01640 74c5ddd39ad830fbe2c040ece1a7ebfb 130 Pfam PF07007 Lysozyme inhibitor LprI 26 113 1.3E-22 T 12-10-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal MIM_c01640 74c5ddd39ad830fbe2c040ece1a7ebfb 130 Gene3D G3DSA:1.20.1270.180 24 127 1.2E-22 T 12-10-2018 MIM_c01640 74c5ddd39ad830fbe2c040ece1a7ebfb 130 ProDom PD498860 RC0070 96 126 0.001 T 12-10-2018 MIM_c37820 21683b74e0182c5ac1d1a289e9ad0a49 263 Pfam PF01061 ABC-2 type transporter 16 223 1.3E-14 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MIM_c37820 21683b74e0182c5ac1d1a289e9ad0a49 263 PRINTS PR00164 ABC-2 type transport system membrane protein signature 144 168 4.2E-18 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MIM_c37820 21683b74e0182c5ac1d1a289e9ad0a49 263 PRINTS PR00164 ABC-2 type transport system membrane protein signature 66 88 4.2E-18 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MIM_c37820 21683b74e0182c5ac1d1a289e9ad0a49 263 PRINTS PR00164 ABC-2 type transport system membrane protein signature 201 220 4.2E-18 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MIM_c37820 21683b74e0182c5ac1d1a289e9ad0a49 263 PRINTS PR00164 ABC-2 type transport system membrane protein signature 181 200 4.2E-18 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MIM_c37820 21683b74e0182c5ac1d1a289e9ad0a49 263 PRINTS PR00164 ABC-2 type transport system membrane protein signature 109 134 4.2E-18 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MIM_c37820 21683b74e0182c5ac1d1a289e9ad0a49 263 PRINTS PR00164 ABC-2 type transport system membrane protein signature 35 56 4.2E-18 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MIM_c11630 769677919ba480e12cd87de6deb2ea74 390 Pfam PF05762 VWA domain containing CoxE-like protein 183 269 1.8E-7 T 12-10-2018 IPR008912 Uncharacterised protein family CoxE-like MIM_c33760 7df556c04bc7d2967b458f318d216f3f 131 Pfam PF13665 Domain of unknown function (DUF4150) 13 113 5.8E-31 T 12-10-2018 IPR025425 Domain of unknown function DUF4150 MIM_c29400 3554097c3bc917ff2a39782acccec9fd 344 Pfam PF11906 Protein of unknown function (DUF3426) 192 340 3.1E-33 T 12-10-2018 IPR021834 Protein of unknown function DUF3426 MIM_c29400 3554097c3bc917ff2a39782acccec9fd 344 Pfam PF13717 zinc-ribbon domain 1 36 1.4E-10 T 12-10-2018 IPR011723 Zinc finger/thioredoxin putative MIM_c29400 3554097c3bc917ff2a39782acccec9fd 344 TIGRFAM TIGR02098 MJ0042_CXXC: MJ0042 family finger-like domain 1 38 4.5E-13 T 12-10-2018 IPR011723 Zinc finger/thioredoxin putative MIM_c06340 a42525bc198e5a47dafd38e2aee2f5ac 264 Gene3D G3DSA:1.10.3720.10 59 250 1.7E-21 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c06340 a42525bc198e5a47dafd38e2aee2f5ac 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 246 1.6E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c06340 a42525bc198e5a47dafd38e2aee2f5ac 264 SUPERFAMILY SSF161098 60 241 1.44E-28 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c10200 1ca7bf8a23a3b480ab9bf6e7e746d7ad 184 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 108 127 4.3E-34 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MIM_c10200 1ca7bf8a23a3b480ab9bf6e7e746d7ad 184 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 5 18 4.3E-34 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MIM_c10200 1ca7bf8a23a3b480ab9bf6e7e746d7ad 184 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 62 78 4.3E-34 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MIM_c10200 1ca7bf8a23a3b480ab9bf6e7e746d7ad 184 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 84 100 4.3E-34 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MIM_c10200 1ca7bf8a23a3b480ab9bf6e7e746d7ad 184 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 139 151 4.3E-34 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MIM_c10200 1ca7bf8a23a3b480ab9bf6e7e746d7ad 184 SUPERFAMILY SSF53098 2 155 3.79E-51 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily MIM_c10200 1ca7bf8a23a3b480ab9bf6e7e746d7ad 184 Gene3D G3DSA:3.30.420.10 4 156 9.2E-49 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MIM_c10200 1ca7bf8a23a3b480ab9bf6e7e746d7ad 184 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 114 148 - T 12-10-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 MIM_c10200 1ca7bf8a23a3b480ab9bf6e7e746d7ad 184 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 4 151 1.1E-55 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MIM_c10200 1ca7bf8a23a3b480ab9bf6e7e746d7ad 184 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 4 154 2.0E-49 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MIM_c10200 1ca7bf8a23a3b480ab9bf6e7e746d7ad 184 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 2 154 47.002 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MIM_c04200 702cadc3f6430cc5c1eda53bf1c76782 182 Pfam PF00857 Isochorismatase family 5 177 7.2E-39 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 MIM_c04200 702cadc3f6430cc5c1eda53bf1c76782 182 SUPERFAMILY SSF52499 3 181 7.72E-50 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MIM_c04200 702cadc3f6430cc5c1eda53bf1c76782 182 Gene3D G3DSA:3.40.50.850 2 182 2.7E-50 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MIM_c04600 5255e37593becd8147acdb102bfa7062 343 Pfam PF02628 Cytochrome oxidase assembly protein 15 326 8.2E-81 T 12-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 MIM_c22440 5f6685d57f1e001f6fc4aa6e8f86d7a6 361 Gene3D G3DSA:3.60.21.10 19 345 7.6E-38 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like MIM_c22440 5f6685d57f1e001f6fc4aa6e8f86d7a6 361 SUPERFAMILY SSF56300 6 199 4.14E-32 T 12-10-2018 MIM_c22440 5f6685d57f1e001f6fc4aa6e8f86d7a6 361 Pfam PF00149 Calcineurin-like phosphoesterase 18 191 1.4E-13 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MIM_c00370 f0696c63a0e9bb03faee595831bacaa8 278 Gene3D G3DSA:3.20.20.140 8 276 1.5E-50 T 12-10-2018 MIM_c00370 f0696c63a0e9bb03faee595831bacaa8 278 SUPERFAMILY SSF51556 31 277 1.02E-40 T 12-10-2018 IPR032466 Metal-dependent hydrolase MIM_c00370 f0696c63a0e9bb03faee595831bacaa8 278 Pfam PF04909 Amidohydrolase 47 276 1.3E-20 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MIM_c38870 63fb784432c904686cd0c92570e95ce1 543 Pfam PF08811 Protein of unknown function (DUF1800) 68 537 4.4E-126 T 12-10-2018 IPR014917 Protein of unknown function DUF1800 MIM_c29850 0caaadef2482da8626a9701774b5bcc0 178 Gene3D G3DSA:3.30.1060.10 1 166 1.1E-67 T 12-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MIM_c29850 0caaadef2482da8626a9701774b5bcc0 178 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 6 157 5.1E-55 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MIM_c29850 0caaadef2482da8626a9701774b5bcc0 178 Pfam PF01625 Peptide methionine sulfoxide reductase 8 157 7.5E-61 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MIM_c29850 0caaadef2482da8626a9701774b5bcc0 178 SUPERFAMILY SSF55068 3 168 6.02E-72 T 12-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MIM_c29850 0caaadef2482da8626a9701774b5bcc0 178 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 5 162 34.964 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MIM_c36850 7d71d360f69ec222c9306a7b44e88219 164 Gene3D G3DSA:3.90.1720.70 1 164 2.1E-59 T 12-10-2018 MIM_c36850 7d71d360f69ec222c9306a7b44e88219 164 Pfam PF14113 Type VI secretion system (T6SS), amidase effector protein 4 42 143 2.9E-21 T 12-10-2018 IPR025562 Type VI secretion system (T6SS), amidase effector protein 4 MIM_c23490 f77f41fe4c9080e79ff91854ca7ff40b 78 Pfam PF00830 Ribosomal L28 family 3 62 8.2E-30 T 12-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c23490 f77f41fe4c9080e79ff91854ca7ff40b 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 4.7E-30 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c23490 f77f41fe4c9080e79ff91854ca7ff40b 78 Gene3D G3DSA:2.30.170.40 2 78 1.9E-34 T 12-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c23490 f77f41fe4c9080e79ff91854ca7ff40b 78 SUPERFAMILY SSF143800 2 76 2.94E-33 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MIM_c23490 f77f41fe4c9080e79ff91854ca7ff40b 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 22.483 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MIM_c40320 f7338eb909b3cb35e1d9ac710556ef60 313 Pfam PF05853 beta-keto acid cleavage enzyme 9 305 4.0E-106 T 12-10-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247 MIM_c40320 f7338eb909b3cb35e1d9ac710556ef60 313 Gene3D G3DSA:3.20.20.70 4 313 7.2E-130 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c10300 f8d3d94dffa89b71f54d9a649fabb2ff 106 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 7 103 8.5E-19 T 12-10-2018 IPR008407 Branched-chain amino acid transport, AzlD MIM_c04780 5de5bcd4c35c359c4ad2716c389e3ebc 330 PRINTS PR01805 VacJ lipoprotein signature 99 116 1.9E-26 T 12-10-2018 IPR007428 MlaA lipoprotein GO:0016020 MIM_c04780 5de5bcd4c35c359c4ad2716c389e3ebc 330 PRINTS PR01805 VacJ lipoprotein signature 48 64 1.9E-26 T 12-10-2018 IPR007428 MlaA lipoprotein GO:0016020 MIM_c04780 5de5bcd4c35c359c4ad2716c389e3ebc 330 PRINTS PR01805 VacJ lipoprotein signature 135 152 1.9E-26 T 12-10-2018 IPR007428 MlaA lipoprotein GO:0016020 MIM_c04780 5de5bcd4c35c359c4ad2716c389e3ebc 330 PRINTS PR01805 VacJ lipoprotein signature 31 44 1.9E-26 T 12-10-2018 IPR007428 MlaA lipoprotein GO:0016020 MIM_c04780 5de5bcd4c35c359c4ad2716c389e3ebc 330 Pfam PF04333 MlaA lipoprotein 31 227 9.2E-72 T 12-10-2018 IPR007428 MlaA lipoprotein GO:0016020 MIM_c12820 f48c45ec88845126f21c3aec05c576f4 376 Pfam PF03929 PepSY-associated TM region 10 364 1.0E-54 T 12-10-2018 IPR005625 PepSY-associated TM protein MIM_c17510 dae4dd5139fc7f787f9eb9a79ef2bdc0 277 TIGRFAM TIGR02312 HpaH: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase 1 276 4.3E-129 T 12-10-2018 IPR012690 2-oxo-hepta-4-ene-1,7-dioic acid hydratase GO:0018817|GO:0019439 MIM_c17510 dae4dd5139fc7f787f9eb9a79ef2bdc0 277 Gene3D G3DSA:3.90.850.10 2 276 1.9E-71 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MIM_c17510 dae4dd5139fc7f787f9eb9a79ef2bdc0 277 SUPERFAMILY SSF56529 5 276 1.18E-66 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MIM_c37870 72ec88388ca41e10ee3a60fb022043fc 460 Pfam PF02447 GntP family permease 3 308 1.5E-6 T 12-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 MIM_c08720 3da362a05fa717d42ce25c6e4888e475 178 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 28 165 7.3E-14 T 12-10-2018 IPR009936 Protein of unknown function DUF1468 MIM_c13850 2fc6ad5a20d29dda5069440a927ef5ab 185 Pfam PF11136 Protein of unknown function (DUF2889) 13 136 2.0E-39 T 12-10-2018 IPR021312 Protein of unknown function DUF2889 MIM_c19530 2abde8b5166f7ee301714d14d494212a 151 Pfam PF01957 NfeD-like C-terminal, partner-binding 3 140 5.5E-9 T 12-10-2018 IPR002810 NfeD-like, C-terminal domain MIM_c33540 2c21384352193ad0e47b795743ef0fb3 246 Pfam PF01925 Sulfite exporter TauE/SafE 21 240 9.8E-19 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MIM_c23530 a7cb8a3d8ec4564f4832ff05a0697e7e 341 Pfam PF03601 Conserved hypothetical protein 698 19 320 5.9E-81 T 12-10-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 MIM_c35240 8a9c9c169a24f7fe9d83b199d472ea55 361 Pfam PF04829 Pre-toxin domain with VENN motif 2 41 9.1E-9 T 12-10-2018 IPR006914 VENN motif-containing domain MIM_c22320 ead021f2d237e853d4303159a30f7b88 249 SUPERFAMILY SSF52540 9 241 5.89E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c22320 ead021f2d237e853d4303159a30f7b88 249 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MIM_c22320 ead021f2d237e853d4303159a30f7b88 249 Gene3D G3DSA:3.40.50.300 7 248 5.3E-74 T 12-10-2018 MIM_c22320 ead021f2d237e853d4303159a30f7b88 249 SMART SM00382 34 223 4.0E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c22320 ead021f2d237e853d4303159a30f7b88 249 PIRSF PIRSF039085 6 249 1.9E-100 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MIM_c22320 ead021f2d237e853d4303159a30f7b88 249 Pfam PF00005 ABC transporter 25 175 1.6E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MIM_c03720 5428cc2afb49c584007241385f39f09e 461 Pfam PF11067 Protein of unknown function (DUF2868) 148 441 6.7E-75 T 12-10-2018 IPR021296 Protein of unknown function DUF2868 MIM_c15420 3e1aeeee21b24990bbbe13a339e2be98 157 Pfam PF05154 TM2 domain 89 139 8.2E-14 T 12-10-2018 IPR007829 TM2 domain MIM_c07340 cf9c8e532ef1f6da3d2a893c7169bf5d 305 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 13 282 25.592 T 12-10-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00780+2.1.1.197|MetaCyc: PWY-6519 MIM_c07340 cf9c8e532ef1f6da3d2a893c7169bf5d 305 Gene3D G3DSA:3.40.50.150 7 228 2.7E-28 T 12-10-2018 MIM_c07340 cf9c8e532ef1f6da3d2a893c7169bf5d 305 Pfam PF08241 Methyltransferase domain 57 165 1.7E-17 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 MIM_c07340 cf9c8e532ef1f6da3d2a893c7169bf5d 305 SUPERFAMILY SSF53335 36 235 1.15E-30 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c29110 fade2ce56827ac8b4df645c954c8e690 280 SMART SM00244 26 189 3.0E-4 T 12-10-2018 IPR001107 Band 7 domain MIM_c29110 fade2ce56827ac8b4df645c954c8e690 280 Pfam PF01145 SPFH domain / Band 7 family 30 210 7.2E-30 T 12-10-2018 IPR001107 Band 7 domain MIM_c29110 fade2ce56827ac8b4df645c954c8e690 280 Gene3D G3DSA:3.30.479.30 54 192 1.2E-9 T 12-10-2018 MIM_c29110 fade2ce56827ac8b4df645c954c8e690 280 SUPERFAMILY SSF117892 58 194 6.54E-15 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily MIM_c24320 4ef50f55cd2c79dd338a5f0af55cae76 380 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 205 376 4.3E-46 T 12-10-2018 IPR005273 Uracil-DNA glycosylase family 4 MIM_c24320 4ef50f55cd2c79dd338a5f0af55cae76 380 Gene3D G3DSA:3.40.470.10 194 380 9.5E-54 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MIM_c24320 4ef50f55cd2c79dd338a5f0af55cae76 380 SMART SM00986 219 369 4.6E-23 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MIM_c24320 4ef50f55cd2c79dd338a5f0af55cae76 380 SUPERFAMILY SSF52141 195 377 1.24E-48 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MIM_c24320 4ef50f55cd2c79dd338a5f0af55cae76 380 SMART SM00987 219 369 4.6E-23 T 12-10-2018 MIM_c24320 4ef50f55cd2c79dd338a5f0af55cae76 380 Pfam PF03167 Uracil DNA glycosylase superfamily 219 369 1.5E-32 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MIM_c11010 0311f7b48ac46b7bfb5be7dd6e1ddb23 161 SUPERFAMILY SSF53955 4 153 7.67E-53 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily MIM_c11010 0311f7b48ac46b7bfb5be7dd6e1ddb23 161 Pfam PF00959 Phage lysozyme 32 146 1.9E-21 T 12-10-2018 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 MIM_c11010 0311f7b48ac46b7bfb5be7dd6e1ddb23 161 Gene3D G3DSA:1.10.530.40 6 159 6.4E-60 T 12-10-2018 MIM_c27900 375230496fa0b30b91a845952b81c31e 105 Pfam PF05957 Bacterial protein of unknown function (DUF883) 13 105 1.8E-24 T 12-10-2018 IPR010279 Inner membrane protein YqjD/ElaB GO:0043022 MIM_c33740 747859d7e85c8354c3a27e227696bbe6 705 Pfam PF04632 Fusaric acid resistance protein family 38 693 4.3E-181 T 12-10-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0022857|GO:0055085 MIM_c11640 6d93ae7bbe41c3455107f918a053e870 290 SMART SM00382 35 193 1.6E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain MIM_c11640 6d93ae7bbe41c3455107f918a053e870 290 SUPERFAMILY SSF52540 18 219 7.13E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c11640 6d93ae7bbe41c3455107f918a053e870 290 Gene3D G3DSA:3.40.50.300 11 215 1.7E-28 T 12-10-2018 MIM_c11640 6d93ae7bbe41c3455107f918a053e870 290 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 39 185 5.1E-14 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MIM_c30790 459044c3e8ed23390e1dd243c9922e2c 178 SUPERFAMILY SSF52518 7 165 2.65E-12 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold MIM_c30790 459044c3e8ed23390e1dd243c9922e2c 178 Gene3D G3DSA:3.40.50.970 3 174 1.5E-5 T 12-10-2018 MIM_c16660 9093de39a235421c2b34f21c9906c9d4 142 Pfam PF09842 Predicted membrane protein (DUF2069) 28 130 8.7E-33 T 12-10-2018 IPR018643 Protein of unknown function DUF2069, membrane MIM_c00670 c961496d3729941d4accff4d9de7d540 203 Gene3D G3DSA:3.55.50.30 33 115 6.9E-18 T 12-10-2018 MIM_c37830 8c4930054aa40935bec109a00a408833 373 Pfam PF10531 SLBB domain 181 223 0.0074 T 12-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MIM_c37830 8c4930054aa40935bec109a00a408833 373 Gene3D G3DSA:3.10.560.10 257 345 8.0E-59 T 12-10-2018 MIM_c37830 8c4930054aa40935bec109a00a408833 373 Pfam PF02563 Polysaccharide biosynthesis/export protein 90 169 1.1E-13 T 12-10-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 MIM_c37830 8c4930054aa40935bec109a00a408833 373 Gene3D G3DSA:3.30.1950.10 93 176 8.0E-59 T 12-10-2018 MIM_c37830 8c4930054aa40935bec109a00a408833 373 Gene3D G3DSA:3.10.560.10 85 256 8.0E-59 T 12-10-2018 MIM_c26760 aa3ff83fd7599c4389af08837bf4e313 351 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 20 332 5.9E-53 T 12-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MIM_c30500 4747b67e1a8e74847937699e0e09eb03 233 Gene3D G3DSA:3.40.50.1820 2 231 2.9E-31 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c30500 4747b67e1a8e74847937699e0e09eb03 233 Pfam PF12697 Alpha/beta hydrolase family 13 224 5.5E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MIM_c30500 4747b67e1a8e74847937699e0e09eb03 233 SUPERFAMILY SSF53474 9 230 3.77E-31 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c01910 66761423428afa1f9d64118f95111dbd 425 PIRSF PIRSF006066 1 425 3.0E-156 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 MIM_c01910 66761423428afa1f9d64118f95111dbd 425 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 421 1.3E-146 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 MIM_c01910 66761423428afa1f9d64118f95111dbd 425 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 416 5.6E-125 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit MIM_c39870 f1da6b6bc9de56b11453f53faf88a64d 495 Pfam PF02653 Branched-chain amino acid transport system / permease component 190 474 4.1E-44 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c25340 ab09681fcad475b801cb204df9c6169c 363 SUPERFAMILY SSF51395 3 350 9.04E-102 T 12-10-2018 MIM_c25340 ab09681fcad475b801cb204df9c6169c 363 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 341 3.2E-73 T 12-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 MIM_c25340 ab09681fcad475b801cb204df9c6169c 363 Gene3D G3DSA:3.20.20.70 1 360 8.2E-107 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c02760 515a0de35b525b4b6b82df70a443eafc 70 SUPERFAMILY SSF55008 9 66 6.41E-16 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 MIM_c02760 515a0de35b525b4b6b82df70a443eafc 70 Pfam PF00403 Heavy-metal-associated domain 9 66 6.4E-13 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MIM_c02760 515a0de35b525b4b6b82df70a443eafc 70 Gene3D G3DSA:3.30.70.100 5 70 5.6E-19 T 12-10-2018 MIM_c08570 5b4ca4feaed6bff257e95ec234c19258 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 324 1.3E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c08570 5b4ca4feaed6bff257e95ec234c19258 328 PIRSF PIRSF017082 1 328 1.2E-80 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 MIM_c08570 5b4ca4feaed6bff257e95ec234c19258 328 SUPERFAMILY SSF53850 116 292 2.85E-14 T 12-10-2018 MIM_c08570 5b4ca4feaed6bff257e95ec234c19258 328 Gene3D G3DSA:3.40.190.10 130 253 5.1E-104 T 12-10-2018 MIM_c08570 5b4ca4feaed6bff257e95ec234c19258 328 Gene3D G3DSA:3.40.190.150 33 318 5.1E-104 T 12-10-2018 MIM_c23030 b45a6cecd0b67aeb537aa90390cf0c27 191 Pfam PF04239 Protein of unknown function (DUF421) 99 161 2.1E-14 T 12-10-2018 IPR007353 Protein of unknown function DUF421 MIM_c23030 b45a6cecd0b67aeb537aa90390cf0c27 191 Gene3D G3DSA:3.30.240.20 93 163 4.5E-19 T 12-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily MIM_c37630 dc2afd68a9e50a47c730b374f764061c 674 Pfam PF05159 Capsule polysaccharide biosynthesis protein 53 128 3.7E-9 T 12-10-2018 IPR007833 Capsule polysaccharide biosynthesis GO:0000271|GO:0015774 MIM_c37630 dc2afd68a9e50a47c730b374f764061c 674 Pfam PF05159 Capsule polysaccharide biosynthesis protein 393 619 2.1E-35 T 12-10-2018 IPR007833 Capsule polysaccharide biosynthesis GO:0000271|GO:0015774 MIM_c37630 dc2afd68a9e50a47c730b374f764061c 674 Pfam PF05159 Capsule polysaccharide biosynthesis protein 157 306 3.9E-31 T 12-10-2018 IPR007833 Capsule polysaccharide biosynthesis GO:0000271|GO:0015774 MIM_c27430 58b7b4e44fbf0d95f204177b9e052171 227 Pfam PF04172 LrgB-like family 11 223 5.9E-69 T 12-10-2018 IPR007300 CidB/LrgB family MIM_c34390 3773676c5513479fdffe9f3beabcde31 439 TIGRFAM TIGR00843 benE: benzoate transporter 37 409 2.0E-67 T 12-10-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 MIM_c34390 3773676c5513479fdffe9f3beabcde31 439 Pfam PF03594 Benzoate membrane transport protein 34 409 2.6E-81 T 12-10-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 MIM_c20150 3695e971e9b558f0f3716069d18c0398 392 Gene3D G3DSA:3.40.47.10 5 389 1.0E-118 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c20150 3695e971e9b558f0f3716069d18c0398 392 SUPERFAMILY SSF53901 32 357 1.12E-29 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 MIM_c20150 3695e971e9b558f0f3716069d18c0398 392 PIRSF PIRSF000429 6 388 2.6E-33 T 12-10-2018 IPR002155 Thiolase GO:0016747 MIM_c16230 8518ec27671f4bae7fa0f567851a48b8 470 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 19 64 3.3E-5 T 12-10-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal MIM_c08350 b9cac409c7f829e0b0c0e716e63bdf27 169 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 30 159 3.4E-27 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ MIM_c12150 21bee48c75f154754da672ba4db47bb2 227 Pfam PF02666 Phosphatidylserine decarboxylase 44 209 2.8E-30 T 12-10-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 MIM_c12150 21bee48c75f154754da672ba4db47bb2 227 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 11 213 4.5E-68 T 12-10-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 MIM_c12150 21bee48c75f154754da672ba4db47bb2 227 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 10 215 37.08 T 12-10-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 MIM_c27500 5183c4001ed87cc2264c2054b98b82b1 217 SUPERFAMILY SSF161098 13 200 6.8E-45 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c27500 5183c4001ed87cc2264c2054b98b82b1 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 215 6.0E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c27500 5183c4001ed87cc2264c2054b98b82b1 217 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 109 1.9E-28 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c27500 5183c4001ed87cc2264c2054b98b82b1 217 Gene3D G3DSA:1.10.3720.10 6 216 2.7E-54 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c32620 2ad6409ae0e3e8609345017cc8d7ff88 225 SUPERFAMILY SSF47240 64 200 7.26E-17 T 12-10-2018 IPR009078 Ferritin-like superfamily MIM_c32620 2ad6409ae0e3e8609345017cc8d7ff88 225 Hamap MF_01658 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase [coq7]. 22 225 30.33 T 12-10-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 MIM_c32620 2ad6409ae0e3e8609345017cc8d7ff88 225 Pfam PF03232 Ubiquinone biosynthesis protein COQ7 65 224 1.4E-42 T 12-10-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 MIM_c35190 2868d18fe63bd5bc3c16ba66b0123661 169 PIRSF PIRSF015278 1 169 1.7E-47 T 12-10-2018 IPR016630 Uncharacterised conserved protein UCP015278 MIM_c35190 2868d18fe63bd5bc3c16ba66b0123661 169 Pfam PF10004 Uncharacterized protein conserved in bacteria (DUF2247) 8 163 3.3E-56 T 12-10-2018 IPR016630 Uncharacterised conserved protein UCP015278 MIM_c05750 53d0c026f37c5cb10ec37d11f3f0b3ff 209 Pfam PF02036 SCP-2 sterol transfer family 17 114 2.8E-7 T 12-10-2018 IPR003033 SCP2 sterol-binding domain MIM_c20010 43d36d6645361c10187afd1754a90143 207 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 32 160 5.9E-20 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ MIM_c36250 40c5a2b3d648ef5503de3e369afe494f 424 Pfam PF05231 MASE1 17 300 1.4E-17 T 12-10-2018 IPR007895 MASE1 MIM_c36250 40c5a2b3d648ef5503de3e369afe494f 424 Gene3D G3DSA:3.30.450.20 319 369 1.1E-5 T 12-10-2018 MIM_c09220 e4fc503bc331a256e168a45a4316c6d9 236 SUPERFAMILY SSF160950 1 234 1.05E-65 T 12-10-2018 IPR036268 ZapD domain superfamily MIM_c09220 e4fc503bc331a256e168a45a4316c6d9 236 Gene3D G3DSA:2.60.440.10 162 234 7.4E-68 T 12-10-2018 IPR027462 Z ring-associated protein D, C-terminal MIM_c09220 e4fc503bc331a256e168a45a4316c6d9 236 Pfam PF07072 Cell division protein 1 210 1.3E-70 T 12-10-2018 IPR009777 Cell division protein ZapD MIM_c09220 e4fc503bc331a256e168a45a4316c6d9 236 Hamap MF_01092 Cell division protein ZapD [zapD]. 1 234 24.731 T 12-10-2018 IPR009777 Cell division protein ZapD MIM_c09220 e4fc503bc331a256e168a45a4316c6d9 236 Gene3D G3DSA:1.10.3900.10 1 161 7.4E-68 T 12-10-2018 MIM_c04690 2b129f586ea1134d14d0eb2d7b6c7494 237 Gene3D G3DSA:3.30.70.1290 19 153 2.0E-5 T 12-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 MIM_c04690 2b129f586ea1134d14d0eb2d7b6c7494 237 SUPERFAMILY SSF143422 34 105 5.3E-6 T 12-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 MIM_c32150 8ebaedf126a746884b53b86eb6d581c7 556 Gene3D G3DSA:3.40.50.12780 33 449 1.3E-95 T 12-10-2018 MIM_c32150 8ebaedf126a746884b53b86eb6d581c7 556 Gene3D G3DSA:3.30.300.310 452 555 4.5E-26 T 12-10-2018 MIM_c32150 8ebaedf126a746884b53b86eb6d581c7 556 SUPERFAMILY SSF56801 25 552 1.23E-128 T 12-10-2018 MIM_c32150 8ebaedf126a746884b53b86eb6d581c7 556 ProSitePatterns PS00455 Putative AMP-binding domain signature. 215 226 - T 12-10-2018 IPR020845 AMP-binding, conserved site MIM_c32150 8ebaedf126a746884b53b86eb6d581c7 556 Pfam PF00501 AMP-binding enzyme 51 456 1.1E-73 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MIM_c32150 8ebaedf126a746884b53b86eb6d581c7 556 Pfam PF13193 AMP-binding enzyme C-terminal domain 465 543 2.0E-20 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MIM_c26040 840ec56b9d84ce23ee787428e3147fda 453 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 27 430 2.7E-106 T 12-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 MIM_c26040 840ec56b9d84ce23ee787428e3147fda 453 Pfam PF00860 Permease family 31 409 2.4E-92 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 MIM_c26040 840ec56b9d84ce23ee787428e3147fda 453 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 355 375 - T 12-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 MIM_c04010 ad75b2c9103bd1f5eac7e12a8023673f 235 PIRSF PIRSF006232 1 231 4.2E-54 T 12-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 MIM_c04010 ad75b2c9103bd1f5eac7e12a8023673f 235 Pfam PF02678 Pirin 10 119 1.9E-33 T 12-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 MIM_c04010 ad75b2c9103bd1f5eac7e12a8023673f 235 Gene3D G3DSA:2.60.120.10 12 132 3.5E-57 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c04010 ad75b2c9103bd1f5eac7e12a8023673f 235 SUPERFAMILY SSF51182 1 231 1.86E-76 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c04010 ad75b2c9103bd1f5eac7e12a8023673f 235 Gene3D G3DSA:2.60.120.10 133 235 1.4E-34 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c33300 574a44e2e06b62f5233141514f760835 1205 SUPERFAMILY SSF52540 60 370 5.62E-7 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c06410 6cd5020b8de2325ac095417b80f6784d 168 PIRSF PIRSF019217 1 167 5.8E-79 T 12-10-2018 IPR016750 Acetophenone carboxylase beta subunit/Acetone carboxylase gamma subunit MIM_c06410 6cd5020b8de2325ac095417b80f6784d 168 Pfam PF08882 Acetone carboxylase gamma subunit 47 159 7.4E-54 T 12-10-2018 IPR016750 Acetophenone carboxylase beta subunit/Acetone carboxylase gamma subunit MIM_c18270 ffa2bff0727ebe783bbdadd1bda82a5b 190 Pfam PF11136 Protein of unknown function (DUF2889) 12 136 2.0E-38 T 12-10-2018 IPR021312 Protein of unknown function DUF2889 MIM_c15210 c9ca8fd541f528a1f09f669742f3576e 222 Pfam PF00857 Isochorismatase family 14 165 9.4E-18 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 MIM_c15210 c9ca8fd541f528a1f09f669742f3576e 222 Gene3D G3DSA:3.40.50.850 3 210 3.5E-47 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MIM_c15210 c9ca8fd541f528a1f09f669742f3576e 222 SUPERFAMILY SSF52499 6 191 3.27E-41 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MIM_c10120 ff671dc0dda227d40e678499e1d73bfa 260 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 214 234 3.2E-6 T 12-10-2018 IPR024726 Ferric iron reductase, C-terminal GO:0051537 MIM_c14750 a8728af7aae9b18e0448f1bf8aff9183 212 Pfam PF01810 LysE type translocator 16 208 3.8E-33 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MIM_c14750 a8728af7aae9b18e0448f1bf8aff9183 212 PIRSF PIRSF006324 1 212 1.8E-58 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MIM_c19300 1dfa123d00a1b88be804465101e3f2ce 237 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 14 216 1.1E-39 T 12-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 MIM_c19300 1dfa123d00a1b88be804465101e3f2ce 237 Pfam PF01914 MarC family integral membrane protein 14 220 6.7E-42 T 12-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 MIM_c36010 fa863157a5714391de36b8558a92bcfd 191 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 61 142 4.7E-10 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c36010 fa863157a5714391de36b8558a92bcfd 191 SUPERFAMILY SSF46626 43 173 9.74E-22 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c36010 fa863157a5714391de36b8558a92bcfd 191 Gene3D G3DSA:1.10.760.10 37 171 4.3E-55 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MIM_c04650 3c423f051c80d199d1a2673f6f3b9cfb 342 TIGRFAM TIGR01729 taurine_ABC_bnd: taurine ABC transporter, periplasmic binding protein 32 335 8.2E-104 T 12-10-2018 IPR010068 Taurine ABC transporter, substrate-binding protein TauA GO:0015734|GO:0042597 MIM_c04650 3c423f051c80d199d1a2673f6f3b9cfb 342 Gene3D G3DSA:3.40.190.10 33 242 1.9E-50 T 12-10-2018 MIM_c04650 3c423f051c80d199d1a2673f6f3b9cfb 342 SUPERFAMILY SSF53850 29 244 1.76E-44 T 12-10-2018 MIM_c04650 3c423f051c80d199d1a2673f6f3b9cfb 342 SMART SM00062 31 269 1.1E-9 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MIM_c04650 3c423f051c80d199d1a2673f6f3b9cfb 342 Gene3D G3DSA:3.40.190.10 109 207 1.9E-50 T 12-10-2018 MIM_c04650 3c423f051c80d199d1a2673f6f3b9cfb 342 Gene3D G3DSA:1.10.8.450 243 259 1.9E-50 T 12-10-2018 MIM_c04650 3c423f051c80d199d1a2673f6f3b9cfb 342 Pfam PF09084 NMT1/THI5 like 57 241 1.8E-19 T 12-10-2018 IPR015168 SsuA/THI5-like MIM_c37880 bfd8758ad6a35d0e291bfeb77cde4ee0 572 Pfam PF07519 Tannase and feruloyl esterase 79 570 4.5E-111 T 12-10-2018 IPR011118 Tannase/feruloyl esterase MetaCyc: PWY-6784 MIM_c37880 bfd8758ad6a35d0e291bfeb77cde4ee0 572 SUPERFAMILY SSF53474 174 525 1.67E-14 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c16900 0f5827cc2685b54aba396304d0841083 282 Pfam PF04909 Amidohydrolase 20 278 3.2E-34 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MIM_c16900 0f5827cc2685b54aba396304d0841083 282 SUPERFAMILY SSF51556 15 278 4.99E-66 T 12-10-2018 IPR032466 Metal-dependent hydrolase MIM_c16900 0f5827cc2685b54aba396304d0841083 282 Gene3D G3DSA:3.20.20.140 6 282 6.6E-71 T 12-10-2018 MIM_c36230 933fa8fafa78f3060def2b6938375661 328 Pfam PF13387 Domain of unknown function (DUF4105) 120 274 4.8E-41 T 12-10-2018 IPR025178 Domain of unknown function DUF4105 MIM_c01760 82e3be233c2dc3fda19d8358c21221a9 236 Pfam PF03741 Integral membrane protein TerC family 14 190 1.5E-45 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 MIM_c01760 82e3be233c2dc3fda19d8358c21221a9 236 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 12 191 1.7E-71 T 12-10-2018 IPR022301 Integral membrane protein YjbE MIM_c04230 f069281370ccb8e550e405094b715d34 379 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 131 372 1.2E-68 T 12-10-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria MIM_c04230 f069281370ccb8e550e405094b715d34 379 Pfam PF02405 Permease MlaE 163 372 3.4E-67 T 12-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 MIM_c03930 accb23232eb48f27797994f0a380b3e3 351 Pfam PF03060 Nitronate monooxygenase 4 347 4.8E-79 T 12-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 MIM_c03930 accb23232eb48f27797994f0a380b3e3 351 SUPERFAMILY SSF51412 7 336 3.82E-58 T 12-10-2018 MIM_c03930 accb23232eb48f27797994f0a380b3e3 351 Gene3D G3DSA:3.20.20.70 1 350 1.6E-113 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c39990 6b04c9c262d20fbeca4f359d22b36bf7 117 Gene3D G3DSA:1.10.3990.20 9 114 7.9E-33 T 12-10-2018 IPR038268 Ribbon-helix-helix domain superfamily MIM_c39990 6b04c9c262d20fbeca4f359d22b36bf7 117 Pfam PF13467 Ribbon-helix-helix domain 15 82 4.9E-25 T 12-10-2018 IPR027373 Ribbon-helix-helix domain MIM_c35450 14ead1ecb803441ea0791b9d4bd4f4ca 315 Gene3D G3DSA:3.40.710.10 47 313 4.5E-26 T 12-10-2018 MIM_c35450 14ead1ecb803441ea0791b9d4bd4f4ca 315 SUPERFAMILY SSF56601 56 272 5.09E-19 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MIM_c30660 28417012168a3ccfcce81ed8aeca2c5c 654 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 414 645 2.2E-38 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit MIM_c30660 28417012168a3ccfcce81ed8aeca2c5c 654 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 40 301 1.7E-38 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit MIM_c09590 7d5f8cf0704c34bfc6cf84b2fdf07537 114 Pfam PF05336 L-rhamnose mutarotase 5 111 7.8E-27 T 12-10-2018 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 MIM_c09590 7d5f8cf0704c34bfc6cf84b2fdf07537 114 SUPERFAMILY SSF54909 4 111 3.97E-25 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel MIM_c09590 7d5f8cf0704c34bfc6cf84b2fdf07537 114 Gene3D G3DSA:3.30.70.100 3 101 7.9E-12 T 12-10-2018 MIM_c28710 e015fb648ae30b2aae34c0fa6c55eb73 119 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 112 2.4E-10 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MIM_c28710 e015fb648ae30b2aae34c0fa6c55eb73 119 Gene3D G3DSA:3.10.180.10 1 118 3.1E-23 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c28710 e015fb648ae30b2aae34c0fa6c55eb73 119 SUPERFAMILY SSF54593 9 117 2.55E-27 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MIM_c21000 21962a82528f9acc0d61133b27221e10 135 SUPERFAMILY SSF51316 1 135 1.15E-35 T 12-10-2018 IPR011057 Mss4-like superfamily MIM_c21000 21962a82528f9acc0d61133b27221e10 135 Gene3D G3DSA:2.170.150.70 3 115 1.6E-15 T 12-10-2018 MIM_c21000 21962a82528f9acc0d61133b27221e10 135 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 25 117 7.9E-22 T 12-10-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 MIM_c27290 7bf4d6572305e3a04f8d0574c2e0a10b 188 Gene3D G3DSA:3.40.50.150 1 187 3.9E-66 T 12-10-2018 MIM_c27290 7bf4d6572305e3a04f8d0574c2e0a10b 188 Pfam PF06962 Putative rRNA methylase 48 184 1.2E-51 T 12-10-2018 IPR010719 Putative rRNA methylase MIM_c27290 7bf4d6572305e3a04f8d0574c2e0a10b 188 SUPERFAMILY SSF53335 17 139 6.44E-24 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MIM_c13310 0f1accb7280f95650a1a84995e78eb2a 131 Pfam PF07681 DoxX 9 87 8.3E-18 T 12-10-2018 IPR032808 DoxX family MIM_c03740 cd03374118cf594e0e5c3fbfe5d7d02e 82 Pfam PF04226 Transglycosylase associated protein 33 79 2.3E-16 T 12-10-2018 IPR007341 Transglycosylase-associated protein GO:0016021 MIM_c22610 f68171246b029c9b0a062fd43abe8077 209 Pfam PF01810 LysE type translocator 15 201 5.5E-36 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MIM_c22610 f68171246b029c9b0a062fd43abe8077 209 PIRSF PIRSF006324 1 206 2.1E-49 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MIM_c14020 8fa0ee059781b73c805ca9a71f549eb3 173 Pfam PF13403 Hint domain 38 110 1.8E-17 T 12-10-2018 IPR028992 Hedgehog/Intein (Hint) domain MIM_c35370 c27f56380e0ca9dcb5db09893fe32279 274 Gene3D G3DSA:1.10.3720.10 71 270 6.9E-25 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c35370 c27f56380e0ca9dcb5db09893fe32279 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 270 6.7E-25 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c35370 c27f56380e0ca9dcb5db09893fe32279 274 SUPERFAMILY SSF161098 73 255 1.24E-31 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c31470 f2a33e9b7aebb69d60c1838a149f6deb 422 SUPERFAMILY SSF53686 60 402 7.2E-61 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MIM_c31470 f2a33e9b7aebb69d60c1838a149f6deb 422 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 59 392 2.4E-67 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MIM_c31470 f2a33e9b7aebb69d60c1838a149f6deb 422 TIGRFAM TIGR01747 diampropi_NH3ly: diaminopropionate ammonia-lyase family 39 405 6.7E-83 T 12-10-2018 IPR010081 Diaminopropionate ammonia-lyase GO:0008838|GO:0030170 MIM_c31470 f2a33e9b7aebb69d60c1838a149f6deb 422 Gene3D G3DSA:3.40.50.1100 59 405 2.1E-125 T 12-10-2018 MIM_c31470 f2a33e9b7aebb69d60c1838a149f6deb 422 Gene3D G3DSA:3.40.50.1100 92 210 2.1E-125 T 12-10-2018 MIM_c01100 6b8b1255229750950eec7d86532cabcd 284 SUPERFAMILY SSF51197 14 246 5.29E-57 T 12-10-2018 MIM_c01100 6b8b1255229750950eec7d86532cabcd 284 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 19 202 5.5E-30 T 12-10-2018 IPR008775 Phytanoyl-CoA dioxygenase MIM_c01100 6b8b1255229750950eec7d86532cabcd 284 Gene3D G3DSA:2.60.120.620 3 260 3.8E-67 T 12-10-2018 MIM_c36280 6f26f24aebbd872d286cb304400db8e6 144 TIGRFAM TIGR01841 phasin: phasin family protein 56 135 1.2E-10 T 12-10-2018 IPR010127 Phasin, subfamily 1 MIM_c36280 6f26f24aebbd872d286cb304400db8e6 144 Pfam PF09361 Phasin protein 36 127 3.2E-14 T 12-10-2018 IPR018968 Phasin MIM_c39260 1151b414bbd026a6d1e3cd6ce9cea96f 501 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 438 9.0E-155 T 12-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane MIM_c05150 8d15637eb9b6ff8cfd13828d3cdda403 220 Gene3D G3DSA:3.30.450.40 42 218 7.2E-43 T 12-10-2018 IPR029016 GAF-like domain superfamily MIM_c05150 8d15637eb9b6ff8cfd13828d3cdda403 220 SUPERFAMILY SSF55781 88 214 3.64E-5 T 12-10-2018 MIM_c05150 8d15637eb9b6ff8cfd13828d3cdda403 220 Pfam PF04340 Protein of unknown function, DUF484 4 215 4.7E-34 T 12-10-2018 IPR007435 Protein of unknown function DUF484 MIM_c05290 805e74464b41dadc535efaee1199ba9e 89 SUPERFAMILY SSF47598 52 88 5.08E-6 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 MIM_c28240 8b9490dd9ff51fdd28498914e02a1fef 256 Pfam PF01610 Transposase 10 242 1.6E-58 T 12-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain MIM_c11030 53aa75a328909b42cd4c4a8d2da4a4e4 296 Pfam PF07751 Abi-like protein 35 218 1.2E-52 T 12-10-2018 IPR011664 Abortive infection system protein AbiD/AbiF-like MIM_c24780 6eab3a245d1a5badc1e06288d7256708 214 Pfam PF03458 UPF0126 domain 9 82 4.7E-19 T 12-10-2018 IPR005115 Uncharacterised domain UPF0126 MIM_c24780 6eab3a245d1a5badc1e06288d7256708 214 Pfam PF03458 UPF0126 domain 95 166 9.1E-21 T 12-10-2018 IPR005115 Uncharacterised domain UPF0126 MIM_c39820 f8d6db6133b0e04cfdede54f509f1bf5 84 Pfam PF14384 BrnA antitoxin of type II toxin-antitoxin system 13 83 9.3E-18 T 12-10-2018 IPR025528 BrnA antitoxin of type II toxin-antitoxin system MIM_c40300 78555a07c25a95346e29b7a98266d1b8 401 Gene3D G3DSA:3.40.50.2300 150 281 5.1E-100 T 12-10-2018 MIM_c40300 78555a07c25a95346e29b7a98266d1b8 401 Gene3D G3DSA:3.40.50.2300 31 332 5.1E-100 T 12-10-2018 MIM_c40300 78555a07c25a95346e29b7a98266d1b8 401 Pfam PF13458 Periplasmic binding protein 30 366 2.0E-81 T 12-10-2018 IPR028081 Leucine-binding protein domain MIM_c40300 78555a07c25a95346e29b7a98266d1b8 401 SUPERFAMILY SSF53822 30 387 2.12E-82 T 12-10-2018 IPR028082 Periplasmic binding protein-like I MIM_c19560 e4d46be3a55429a344ce4f1390b6033a 144 SUPERFAMILY SSF55961 1 144 3.73E-36 T 12-10-2018 MIM_c19560 e4d46be3a55429a344ce4f1390b6033a 144 Gene3D G3DSA:3.30.530.20 3 144 6.8E-39 T 12-10-2018 IPR023393 START-like domain superfamily MIM_c19560 e4d46be3a55429a344ce4f1390b6033a 144 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 11 135 3.8E-35 T 12-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 MIM_c08400 ae1b4cb9932133a98969bf784d7d09d2 456 Pfam PF07287 Acyclic terpene utilisation family protein AtuA 6 353 1.5E-121 T 12-10-2018 IPR010839 Acyclic terpene utilisation MIM_c01780 8127971589ab30bac4ee266728273a41 565 Gene3D G3DSA:1.20.1730.10 32 471 1.4E-49 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily MIM_c01780 8127971589ab30bac4ee266728273a41 565 Pfam PF00474 Sodium:solute symporter family 43 424 4.1E-26 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MIM_c20270 146032f585653057417bcff16ff15d7f 272 Pfam PF02653 Branched-chain amino acid transport system / permease component 35 272 1.8E-36 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c08480 25ab018c6c02c968ae879683064e702d 231 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 40 223 8.9E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c08480 25ab018c6c02c968ae879683064e702d 231 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 23 116 1.1E-23 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MIM_c08480 25ab018c6c02c968ae879683064e702d 231 Gene3D G3DSA:1.10.3720.10 16 227 9.2E-48 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c08480 25ab018c6c02c968ae879683064e702d 231 SUPERFAMILY SSF161098 21 208 2.75E-41 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c37840 f11950b10b715a0ce6a0b303f9e715e9 369 Pfam PF02706 Chain length determinant protein 7 61 3.7E-6 T 12-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 MIM_c39100 43ade138b53bcdb0b880d007730e44fc 278 SUPERFAMILY SSF161098 12 268 1.03E-60 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c39100 43ade138b53bcdb0b880d007730e44fc 278 Gene3D G3DSA:1.10.3720.10 13 272 4.3E-56 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c39100 43ade138b53bcdb0b880d007730e44fc 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 268 9.0E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c06390 4dce49bf56fab967f9fb44170ed845ea 715 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 11 198 6.0E-37 T 12-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 MIM_c06390 4dce49bf56fab967f9fb44170ed845ea 715 SUPERFAMILY SSF53067 10 325 6.78E-7 T 12-10-2018 MIM_c06390 4dce49bf56fab967f9fb44170ed845ea 715 Pfam PF01968 Hydantoinase/oxoprolinase 224 509 3.0E-78 T 12-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 MIM_c38580 8334c56e754dbf33135a75ace7932c95 227 Pfam PF11010 Protein of unknown function (DUF2848) 25 218 1.1E-78 T 12-10-2018 IPR021269 Protein of unknown function DUF2848 MIM_c26450 ab6d664ce72ac9bb1dcff92277580ec9 517 SUPERFAMILY SSF51905 1 250 1.65E-11 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MIM_c26450 ab6d664ce72ac9bb1dcff92277580ec9 517 Pfam PF13454 FAD-NAD(P)-binding 8 172 3.3E-33 T 12-10-2018 IPR038732 FAD-dependent urate hydroxylase HpyO, FAD/NAD(P)-binding domain MIM_c01630 98bda4cdf8ba92137ae3737ef4321bdb 183 Gene3D G3DSA:3.40.50.300 9 153 3.7E-9 T 12-10-2018 MIM_c01630 98bda4cdf8ba92137ae3737ef4321bdb 183 SUPERFAMILY SSF52540 14 126 3.65E-13 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c20140 ecf5260d172ee5cb25c1d11256e1f1a2 154 Gene3D G3DSA:3.10.129.10 4 154 8.6E-45 T 12-10-2018 MIM_c20140 ecf5260d172ee5cb25c1d11256e1f1a2 154 Pfam PF01575 MaoC like domain 17 127 1.8E-21 T 12-10-2018 IPR002539 MaoC-like dehydratase domain MIM_c20140 ecf5260d172ee5cb25c1d11256e1f1a2 154 SUPERFAMILY SSF54637 6 153 2.54E-38 T 12-10-2018 IPR029069 HotDog domain superfamily MIM_c11360 d2fef378231f624ab5747177ee691637 269 Pfam PF02104 SURF1 family 12 248 1.6E-40 T 12-10-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MIM_c12430 8935c0a7df3daf4af1d5492a400f93b4 284 Pfam PF02673 Bacitracin resistance protein BacA 10 274 1.1E-82 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MIM_c12430 8935c0a7df3daf4af1d5492a400f93b4 284 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 5 279 17.659 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MIM_c12430 8935c0a7df3daf4af1d5492a400f93b4 284 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 10 272 2.4E-71 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MIM_c21320 efcb9c12cc9b98964f15ce9dbc4ede5f 190 Gene3D G3DSA:3.30.1360.200 67 189 9.9E-11 T 12-10-2018 MIM_c15850 b4c1377b14baafb196bc41eae41ec5f6 181 Gene3D G3DSA:2.60.120.1140 43 169 3.6E-38 T 12-10-2018 IPR038695 Saro_0823-like superfamily MIM_c15850 b4c1377b14baafb196bc41eae41ec5f6 181 Pfam PF02643 Uncharacterized ACR, COG1430 61 162 5.3E-32 T 12-10-2018 IPR003795 Protein of unknown function DUF192 MIM_c38250 a97d6875d47f8d0044020f28f78fcf40 188 SUPERFAMILY SSF48452 55 114 1.52E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MIM_c38250 a97d6875d47f8d0044020f28f78fcf40 188 Gene3D G3DSA:1.25.40.10 41 175 2.4E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MIM_c26870 85d8f77110c2429df9d04405756d055a 194 Pfam PF09998 Uncharacterized protein conserved in bacteria (DUF2239) 8 191 3.8E-76 T 12-10-2018 IPR018715 Protein of unknown function DUF2239 MIM_c30280 793db40462f5fe272dc9d12ab18b6a4b 681 Pfam PF04632 Fusaric acid resistance protein family 10 667 2.3E-170 T 12-10-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0022857|GO:0055085 MIM_c31900 31b558b1c55a198d9d66651bca7fdab7 389 SUPERFAMILY SSF56672 40 234 1.41E-10 T 12-10-2018 MIM_c31900 31b558b1c55a198d9d66651bca7fdab7 389 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 43 241 5.2E-23 T 12-10-2018 IPR000477 Reverse transcriptase domain MIM_c31900 31b558b1c55a198d9d66651bca7fdab7 389 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 52 64 1.4E-20 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c31900 31b558b1c55a198d9d66651bca7fdab7 389 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 147 160 1.4E-20 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c31900 31b558b1c55a198d9d66651bca7fdab7 389 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 180 191 1.4E-20 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c31900 31b558b1c55a198d9d66651bca7fdab7 389 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 99 117 1.4E-20 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c31900 31b558b1c55a198d9d66651bca7fdab7 389 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 83 97 1.4E-20 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c31900 31b558b1c55a198d9d66651bca7fdab7 389 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 38 51 1.4E-20 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c31900 31b558b1c55a198d9d66651bca7fdab7 389 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 238 244 1.4E-20 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MIM_c15570 fcccce113c3acf947b6eb159b3877e2e 129 Pfam PF04247 Invasion gene expression up-regulator, SirB 4 119 3.6E-34 T 12-10-2018 IPR007360 Invasion gene expression up-regulator, SirB MIM_c15570 fcccce113c3acf947b6eb159b3877e2e 129 PIRSF PIRSF005610 1 117 7.2E-23 T 12-10-2018 IPR007360 Invasion gene expression up-regulator, SirB MIM_c06950 e7bbbc51e6b1076d921f43e7f1c406a4 661 Pfam PF01757 Acyltransferase family 18 331 5.9E-23 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 MIM_c06950 e7bbbc51e6b1076d921f43e7f1c406a4 661 SUPERFAMILY SSF52266 511 658 6.83E-8 T 12-10-2018 MIM_c06950 e7bbbc51e6b1076d921f43e7f1c406a4 661 Gene3D G3DSA:3.40.50.1110 414 657 2.0E-6 T 12-10-2018 IPR036514 SGNH hydrolase superfamily MIM_c27020 2f9d3eff2e8eda1a8ea5f514487ccc89 303 Hamap MF_01384 Urease accessory protein UreD [ureD]. 1 259 17.033 T 12-10-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 MIM_c27020 2f9d3eff2e8eda1a8ea5f514487ccc89 303 Pfam PF01774 UreD urease accessory protein 56 231 3.0E-26 T 12-10-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 MIM_c28810 5d83457e09eace78791e59cbe64e904e 580 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 131 141 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MIM_c28810 5d83457e09eace78791e59cbe64e904e 580 Pfam PF00920 Dehydratase family 48 563 7.2E-170 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MIM_c28810 5d83457e09eace78791e59cbe64e904e 580 SUPERFAMILY SSF52016 384 570 4.94E-53 T 12-10-2018 MIM_c28810 5d83457e09eace78791e59cbe64e904e 580 SUPERFAMILY SSF143975 21 383 2.09E-113 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MIM_c28810 5d83457e09eace78791e59cbe64e904e 580 Gene3D G3DSA:3.50.30.80 384 538 1.1E-45 T 12-10-2018 MIM_c04570 24d46799f75ee8214eac4f41691a238a 70 Pfam PF11137 Protein of unknown function (DUF2909) 1 60 4.1E-24 T 12-10-2018 IPR021313 Protein of unknown function DUF2909 MIM_c28040 cce180a7a82b51744ab27d3a93509eee 433 SUPERFAMILY SSF56672 1 174 1.18E-18 T 12-10-2018 MIM_c40360 2028a3f661a5fe33d2e2ceb49fb94235 258 SUPERFAMILY SSF69593 11 236 1.44E-28 T 12-10-2018 MIM_c40360 2028a3f661a5fe33d2e2ceb49fb94235 258 Pfam PF01553 Acyltransferase 88 195 5.6E-16 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MIM_c40360 2028a3f661a5fe33d2e2ceb49fb94235 258 SMART SM00563 90 198 2.9E-22 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MIM_c26230 63a872060e51f5ade063af6ce81fb07f 95 TIGRFAM TIGR02684 dnstrm_HI1420: probable addiction module antidote protein 4 92 2.3E-38 T 12-10-2018 IPR014057 Uncharacterized protein HI1420 MIM_c26230 63a872060e51f5ade063af6ce81fb07f 95 SUPERFAMILY SSF47413 31 89 4.64E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MIM_c38030 4356e6ee986adfcc55119938b1238e07 641 PIRSF PIRSF028304 1 641 3.5E-190 T 12-10-2018 IPR010272 Type VI secretion system, TssF-like MIM_c38030 4356e6ee986adfcc55119938b1238e07 641 TIGRFAM TIGR03359 VI_chp_6: type VI secretion protein, TIGR03359 family 5 640 4.9E-195 T 12-10-2018 IPR010272 Type VI secretion system, TssF-like MIM_c38030 4356e6ee986adfcc55119938b1238e07 641 Pfam PF05947 Type VI secretion system, TssF 6 639 2.7E-225 T 12-10-2018 IPR010272 Type VI secretion system, TssF-like MIM_c21270 40e990e3462d11e7d0d0fee1954fffda 296 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 257 1.3E-30 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c34210 3cb1d57a104a8691b87e911ee47c48c5 392 Gene3D G3DSA:3.40.50.1820 2 389 1.4E-134 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c34210 3cb1d57a104a8691b87e911ee47c48c5 392 SUPERFAMILY SSF53474 5 381 7.62E-96 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold MIM_c34210 3cb1d57a104a8691b87e911ee47c48c5 392 PIRSF PIRSF001112 2 385 7.7E-110 T 12-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 MIM_c34210 3cb1d57a104a8691b87e911ee47c48c5 392 Pfam PF06441 Epoxide hydrolase N terminus 8 120 1.1E-32 T 12-10-2018 IPR010497 Epoxide hydrolase, N-terminal Reactome: R-HSA-211945 MIM_c34210 3cb1d57a104a8691b87e911ee47c48c5 392 PRINTS PR00412 Epoxide hydrolase signature 137 152 1.5E-11 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MIM_c34210 3cb1d57a104a8691b87e911ee47c48c5 392 PRINTS PR00412 Epoxide hydrolase signature 182 195 1.5E-11 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MIM_c34210 3cb1d57a104a8691b87e911ee47c48c5 392 PRINTS PR00412 Epoxide hydrolase signature 359 381 1.5E-11 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MIM_c34210 3cb1d57a104a8691b87e911ee47c48c5 392 PRINTS PR00412 Epoxide hydrolase signature 111 129 1.5E-11 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MIM_c34210 3cb1d57a104a8691b87e911ee47c48c5 392 PRINTS PR00412 Epoxide hydrolase signature 327 343 1.5E-11 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MIM_c23010 3ba08c7a4c87ee44866a43e872f20535 181 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 10 146 2.5E-22 T 12-10-2018 IPR009936 Protein of unknown function DUF1468 MIM_c06970 c10194bb02ebaa600722a5f77bbc7ea2 425 Pfam PF04932 O-Antigen ligase 193 350 1.7E-22 T 12-10-2018 IPR007016 O-antigen ligase-related MIM_c08440 89ef1565a80ee45f86805291116e47e2 224 Gene3D G3DSA:3.50.30.40 23 197 6.7E-51 T 12-10-2018 MIM_c08440 89ef1565a80ee45f86805291116e47e2 224 SUPERFAMILY SSF89562 30 183 7.19E-44 T 12-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily MIM_c08440 89ef1565a80ee45f86805291116e47e2 224 Pfam PF03737 Aldolase/RraA 30 176 3.7E-42 T 12-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MIM_c00170 dd54eb50b62301c7a0f9e95254322e39 114 SUPERFAMILY SSF46785 5 106 1.88E-32 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MIM_c00170 dd54eb50b62301c7a0f9e95254322e39 114 Pfam PF01638 HxlR-like helix-turn-helix 16 104 1.4E-31 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type MIM_c00170 dd54eb50b62301c7a0f9e95254322e39 114 Gene3D G3DSA:1.10.10.10 3 113 1.7E-39 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c21460 9d2a008cf35409842ce2797f037d5d72 429 Pfam PF00860 Permease family 17 391 8.2E-60 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 MIM_c21460 9d2a008cf35409842ce2797f037d5d72 429 PIRSF PIRSF005353 1 429 1.2E-177 T 12-10-2018 IPR026033 Purine permease PbuG-like MIM_c37020 0682262cc8e26c5dc3b835cbd43ba67b 264 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 13 226 1.6E-20 T 12-10-2018 MIM_c07030 80629457214cf9a33be37d6ff3d2022d 309 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 295 2.0E-30 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c23720 ba9ec6fee7c9d8743e7fb26e3636d81c 368 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 3 354 3.8E-96 T 12-10-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 MIM_c23720 ba9ec6fee7c9d8743e7fb26e3636d81c 368 Pfam PF03739 Predicted permease YjgP/YjgQ family 8 355 1.5E-55 T 12-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 MIM_c26280 73f5095b5fe46f5c43def59556f004a1 301 Pfam PF03547 Membrane transport protein 148 293 1.1E-15 T 12-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 MIM_c16110 2360e955c299b28b119339a3e634a858 256 Pfam PF06912 Protein of unknown function (DUF1275) 23 235 1.1E-38 T 12-10-2018 IPR010699 Protein of unknown function DUF1275 MIM_c22910 8e1fed01e6fe40cfa792b494594ba144 186 Pfam PF07209 Protein of unknown function (DUF1415) 10 178 2.0E-66 T 12-10-2018 IPR009858 Protein of unknown function DUF1415 MIM_c38760 a322e09b0f42995aea5b809a9162c6d6 707 Pfam PF05140 ResB-like family 29 695 3.1E-146 T 12-10-2018 IPR007816 ResB-like domain MIM_c03890 7ddd9138aef16e2930853a686d466310 261 Pfam PF11227 Protein of unknown function (DUF3025) 59 260 3.5E-69 T 12-10-2018 IPR021390 Protein of unknown function DUF3025 MIM_c10450 78acad0d35ad78e0dec6511be3dd15d4 408 Pfam PF04143 Sulphur transport 59 388 1.0E-73 T 12-10-2018 IPR007272 Sulphur transport domain MIM_c25250 64520b133001d58a6ccf1aabb3a45a11 144 Pfam PF03788 LrgA family 27 119 1.1E-21 T 12-10-2018 IPR005538 LrgA/CidA family GO:0016021 MIM_c40260 1f9956014163997a51d9397a569ca72c 152 Pfam PF05232 Chlorhexidine efflux transporter 80 143 9.7E-24 T 12-10-2018 IPR007896 Chlorhexidine efflux transporter MIM_c40260 1f9956014163997a51d9397a569ca72c 152 Pfam PF05232 Chlorhexidine efflux transporter 12 73 5.0E-21 T 12-10-2018 IPR007896 Chlorhexidine efflux transporter MIM_c24700 78822b08447dd9fadcb6c4a95e50b737 413 Pfam PF07690 Major Facilitator Superfamily 28 249 1.7E-19 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MIM_c24700 78822b08447dd9fadcb6c4a95e50b737 413 SUPERFAMILY SSF103473 19 400 3.14E-40 T 12-10-2018 IPR036259 MFS transporter superfamily MIM_c24700 78822b08447dd9fadcb6c4a95e50b737 413 Gene3D G3DSA:1.20.1250.20 17 402 1.1E-34 T 12-10-2018 MIM_c35170 3050a9b733736790662356459f4de4be 309 Gene3D G3DSA:3.20.20.70 1 309 7.8E-118 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MIM_c35170 3050a9b733736790662356459f4de4be 309 Pfam PF05853 beta-keto acid cleavage enzyme 6 301 1.3E-101 T 12-10-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247 MIM_c10170 7aad88d351806c88090be4cdb7a3e499 166 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 28 154 5.0E-28 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ MIM_c37150 11937bbf1b757461d587bac56f27e40f 179 Pfam PF11684 Protein of unknown function (DUF2380) 39 169 2.9E-34 T 12-10-2018 IPR021698 Protein of unknown function DUF2380 MIM_c32310 b4e2db96abc6d8434f098b16b0f009ff 187 Pfam PF06250 Protein of unknown function (DUF1016) 20 101 4.6E-25 T 12-10-2018 IPR009362 Protein of unknown function DUF1016 MIM_c09410 125a61ee83a20e2262c5b09ff4086ca9 273 SUPERFAMILY SSF161098 79 259 1.2E-26 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c09410 125a61ee83a20e2262c5b09ff4086ca9 273 Gene3D G3DSA:1.10.3720.10 79 268 3.0E-22 T 12-10-2018 IPR035906 MetI-like superfamily MIM_c09410 125a61ee83a20e2262c5b09ff4086ca9 273 TIGRFAM TIGR01183 ntrB: nitrate ABC transporter, permease protein 65 259 6.5E-70 T 12-10-2018 IPR005889 Nitrate transport permease GO:0015112|GO:0015706|GO:0016021 MIM_c09410 125a61ee83a20e2262c5b09ff4086ca9 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 268 9.6E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MIM_c07680 f33565fa361352432b38607e034239d5 92 Gene3D G3DSA:3.40.50.300 1 80 6.9E-6 T 12-10-2018 MIM_c07220 031920096b3f8c0c556a044d0fd384d7 212 Pfam PF14334 Domain of unknown function (DUF4390) 49 201 1.7E-51 T 12-10-2018 IPR025500 Protein of unknown function DUF4390 MIM_c10290 93a18ab747d4e2f96c7759043075d809 254 Pfam PF03591 AzlC protein 36 179 1.4E-36 T 12-10-2018 IPR011606 Branched-chain amino acid transport, permease MIM_c33520 fe4f2516141fadf695f0238584f36540 485 SUPERFAMILY SSF56235 7 485 2.51E-122 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MIM_c33520 fe4f2516141fadf695f0238584f36540 485 Gene3D G3DSA:3.60.20.40 301 485 2.2E-46 T 12-10-2018 MIM_c33520 fe4f2516141fadf695f0238584f36540 485 Pfam PF01019 Gamma-glutamyltranspeptidase 26 298 4.7E-67 T 12-10-2018 MIM_c33520 fe4f2516141fadf695f0238584f36540 485 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 103 121 1.1E-27 T 12-10-2018 MIM_c33520 fe4f2516141fadf695f0238584f36540 485 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 325 343 1.1E-27 T 12-10-2018 MIM_c33520 fe4f2516141fadf695f0238584f36540 485 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 33 58 1.1E-27 T 12-10-2018 MIM_c33520 fe4f2516141fadf695f0238584f36540 485 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 379 396 1.1E-27 T 12-10-2018 MIM_c33520 fe4f2516141fadf695f0238584f36540 485 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 121 140 1.1E-27 T 12-10-2018 MIM_c33520 fe4f2516141fadf695f0238584f36540 485 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 355 370 1.1E-27 T 12-10-2018 MIM_c06120 2eca609ce4343a2a9f1a8da7f95cd91a 284 Pfam PF06007 Phosphonate metabolism protein PhnJ 8 278 5.8E-147 T 12-10-2018 IPR010306 Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase GO:0016829|GO:0019700|GO:0051539 KEGG: 00440+4.7.1.1|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 MIM_c06120 2eca609ce4343a2a9f1a8da7f95cd91a 284 PIRSF PIRSF011468 1 284 4.9E-157 T 12-10-2018 IPR010306 Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase GO:0016829|GO:0019700|GO:0051539 KEGG: 00440+4.7.1.1|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 MIM_c36390 fb8ef54e1966981bb6e54bfa0475f10d 206 Pfam PF03458 UPF0126 domain 6 80 1.4E-18 T 12-10-2018 IPR005115 Uncharacterised domain UPF0126 MIM_c36390 fb8ef54e1966981bb6e54bfa0475f10d 206 Pfam PF03458 UPF0126 domain 92 163 3.0E-20 T 12-10-2018 IPR005115 Uncharacterised domain UPF0126 MIM_c33070 0ce7363b77a2215f69a47497190feb97 197 Pfam PF02417 Chromate transporter 23 178 1.8E-26 T 12-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 MIM_c18380 6fa4c9a5d3e236ab4ecacc11e8605541 215 Pfam PF17274 Family of unknown function (DUF5339) 150 214 5.2E-16 T 12-10-2018 IPR020493 Uncharacterised protein family HI0310 MIM_c27890 11b2886730684c25ec2189e7ef3dcb10 136 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 7 119 5.8E-19 T 12-10-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III MIM_c01990 5989ec2cfd1203f1421b19d7dee358d7 290 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 275 1.7E-36 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c22120 0a46c08cc8c4d0e281006ad84b54678f 247 PIRSF PIRSF016919 51 246 3.5E-51 T 12-10-2018 IPR007038 Hydrogenase/Urease accessory protein HupE/UreJ protein MIM_c22120 0a46c08cc8c4d0e281006ad84b54678f 247 Pfam PF04955 HupE / UreJ protein 58 242 1.4E-54 T 12-10-2018 IPR007038 Hydrogenase/Urease accessory protein HupE/UreJ protein MIM_c33140 870f0a95921f51ee306be318cbde1168 746 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 80 566 1.2E-145 T 12-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 MIM_c33140 870f0a95921f51ee306be318cbde1168 746 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 118 566 4.1E-131 T 12-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 MIM_c02050 5092c88491f0bead7d6eb27cc430060f 352 SUPERFAMILY SSF144052 141 341 1.16E-16 T 12-10-2018 MIM_c10260 48b7db231feb85ce07040e039b3f1ec1 311 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 28 185 2.5E-29 T 12-10-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related MIM_c10260 48b7db231feb85ce07040e039b3f1ec1 311 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 196 285 7.1E-14 T 12-10-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related MIM_c00770 ab309b6a04b1d16fb77a5bfcd10a2aa4 275 Pfam PF01311 Bacterial export proteins, family 1 25 259 1.1E-50 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MIM_c00770 ab309b6a04b1d16fb77a5bfcd10a2aa4 275 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 33 54 1.7E-22 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MIM_c00770 ab309b6a04b1d16fb77a5bfcd10a2aa4 275 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 196 218 1.7E-22 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MIM_c00770 ab309b6a04b1d16fb77a5bfcd10a2aa4 275 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 218 237 1.7E-22 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MIM_c00770 ab309b6a04b1d16fb77a5bfcd10a2aa4 275 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 94 113 1.7E-22 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MIM_c00770 ab309b6a04b1d16fb77a5bfcd10a2aa4 275 TIGRFAM TIGR01401 fliR_like_III: type III secretion apparatus protein SpaR/YscT/HrcT 23 266 9.0E-58 T 12-10-2018 IPR006304 Type III secretion protein SpaR/YscT GO:0016021 MIM_c30670 35468547fc77c717095f1daffa4b54f3 207 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 27 159 6.4E-26 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ MIM_c00520 dd0af1992f7839715ab23763506f755e 223 Gene3D G3DSA:3.50.30.40 1 172 2.7E-35 T 12-10-2018 MIM_c00520 dd0af1992f7839715ab23763506f755e 223 SUPERFAMILY SSF89562 12 180 2.22E-26 T 12-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily MIM_c00520 dd0af1992f7839715ab23763506f755e 223 Pfam PF03737 Aldolase/RraA 17 168 4.3E-25 T 12-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MIM_c38110 588fa2179bbe2ed16ceec2c16d327ef5 169 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 23 154 3.8E-25 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ MIM_c14170 8fd14e63a0739671c3424f11c7451528 545 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 16 535 1.9E-206 T 12-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 MIM_c14170 8fd14e63a0739671c3424f11c7451528 545 Pfam PF02652 L-lactate permease 16 532 5.3E-202 T 12-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 MIM_c03880 e168a3245d33d120b20eacbb2ec61e2d 275 Pfam PF01925 Sulfite exporter TauE/SafE 10 262 5.0E-53 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MIM_c20280 412307f218197c9eb9f040904acc5d53 291 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 274 8.5E-38 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c13920 735722e1f45cb4114714aa7362a1dd9d 305 Pfam PF02653 Branched-chain amino acid transport system / permease component 25 288 3.1E-33 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c14410 3d7c6d7fa4ad25c8b68b892345c1aa54 182 Pfam PF01292 Prokaryotic cytochrome b561 5 177 1.6E-28 T 12-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 MIM_c14410 3d7c6d7fa4ad25c8b68b892345c1aa54 182 SUPERFAMILY SSF81342 4 178 9.42E-32 T 12-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 MIM_c02410 39a634013eb7d0af11022e43818d8280 86 Pfam PF11903 ParD-like antitoxin of type II bacterial toxin-antitoxin system 1 65 3.7E-27 T 12-10-2018 IPR021831 ParD-like antitoxin of type II bacterial toxin-antitoxin system MIM_c02640 d6fc27e955170eb7bad5adeeb1e12023 203 Pfam PF01810 LysE type translocator 13 197 2.2E-36 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MIM_c22240 84b8b76a170302bb916d636b92b17cba 263 Pfam PF01618 MotA/TolQ/ExbB proton channel family 116 231 1.3E-33 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel MIM_24p00200 8b48fc8fac6d7caf5188bb4916243e40 191 Pfam PF02586 SOS response associated peptidase (SRAP) 3 176 1.4E-28 T 12-10-2018 IPR003738 SOS response associated peptidase (SRAP) MIM_24p00200 8b48fc8fac6d7caf5188bb4916243e40 191 SUPERFAMILY SSF143081 2 173 4.06E-39 T 12-10-2018 IPR036590 SOS response associated peptidase-like MIM_24p00200 8b48fc8fac6d7caf5188bb4916243e40 191 Gene3D G3DSA:3.90.1680.10 2 189 1.2E-38 T 12-10-2018 IPR036590 SOS response associated peptidase-like MIM_c26190 114f3e553dfb0e38fe46bb28fc0358b1 286 Pfam PF01925 Sulfite exporter TauE/SafE 9 272 1.4E-43 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MIM_c19870 49e7b25df09e2a1e1093c9b56b99d2da 323 Pfam PF00487 Fatty acid desaturase 48 272 3.8E-16 T 12-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 MIM_c18120 4e8eb7a2f9f4cedc0c5eb7ce8627a440 73 Pfam PF03891 Domain of unknown function (DUF333) 23 69 6.3E-22 T 12-10-2018 IPR005590 Protein of unknown function DUF333 MIM_c28850 3546eee232004f6b0793452f2956435b 174 SUPERFAMILY SSF55729 41 135 9.17E-5 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase MIM_c21190 510979850260945bfdfab27524fd8439 93 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 34 85 2.0E-16 T 12-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 MIM_c04050 8516daa549b104bb9f7046dc0c4d9e05 142 Pfam PF09722 Protein of unknown function (DUF2384) 90 139 4.2E-17 T 12-10-2018 IPR024467 Domain of unknown function DUF2384 MIM_c04050 8516daa549b104bb9f7046dc0c4d9e05 142 TIGRFAM TIGR02293 TAS_TIGR02293: putative toxin-antitoxin system antitoxin component, TIGR02293 family 21 139 8.1E-21 T 12-10-2018 IPR011979 Conserved hypothetical protein CHP02293 MIM_c38490 16891cb1d0804d6912d39924880c2d60 82 Pfam PF05717 IS66 Orf2 like protein 6 76 4.9E-20 T 12-10-2018 IPR008878 Transposase IS66, Orf2 MIM_c01680 7064b79d1343e917556ca0dae5fcc509 183 Gene3D G3DSA:2.60.120.10 54 181 1.0E-9 T 12-10-2018 IPR014710 RmlC-like jelly roll fold MIM_c01680 7064b79d1343e917556ca0dae5fcc509 183 SUPERFAMILY SSF51182 78 150 8.21E-13 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily MIM_c02580 9f750ef95c170049714b69f4724ce465 150 Pfam PF09980 Predicted membrane protein (DUF2214) 3 147 9.0E-50 T 12-10-2018 IPR018706 Protein of unknown function DUF2214, membrane MIM_c11430 b65e89704ff4826f9d89001cc69b1a4f 252 Pfam PF11459 Transcriptional regulator, AbiEi antitoxin, Type IV TA system 99 245 1.2E-35 T 12-10-2018 IPR021561 Transcriptional regulator, AbiEi 3 antitoxin, Type IV TA system MIM_c11430 b65e89704ff4826f9d89001cc69b1a4f 252 Pfam PF17194 Transcriptional regulator, AbiEi antitoxin N-terminal domain 7 96 1.4E-25 T 12-10-2018 IPR033455 Transcriptional regulator AbiEi antitoxin, N-terminal domain MIM_c03070 c1b7ac1f35de761abaa2358cf6c1b761 118 SUPERFAMILY SSF143120 15 65 6.67E-7 T 12-10-2018 IPR036165 YefM-like superfamily MIM_c25690 510efec39462b13bd078d37db121c164 413 Pfam PF03929 PepSY-associated TM region 13 368 1.9E-60 T 12-10-2018 IPR005625 PepSY-associated TM protein MIM_c25690 510efec39462b13bd078d37db121c164 413 Pfam PF03413 Peptidase propeptide and YPEB domain 62 118 1.0E-4 T 12-10-2018 IPR025711 PepSY domain MIM_c33340 d51510b4951222bf0311c4e02a06f571 1513 SUPERFAMILY SSF52540 350 475 4.98E-5 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MIM_c37500 a88757dd58f9764bcb3574c9cab08dd5 138 Pfam PF04214 Protein of unknown function, DUF 49 118 9.5E-26 T 12-10-2018 IPR007332 Protein of unknown function DUF411 MIM_c10910 26dbfc8bb6e67d306a52bad74b178108 142 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 12 103 3.2E-5 T 12-10-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component MIM_c10910 26dbfc8bb6e67d306a52bad74b178108 142 TIGRFAM TIGR01725 phge_HK97_gp10: phage protein, HK97 gp10 family 8 132 3.3E-14 T 12-10-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component MIM_c12290 0b0b242cb896f983c0cfa52649d87195 371 Pfam PF06804 NlpB/DapX lipoprotein 35 369 5.3E-35 T 12-10-2018 IPR010653 NlpB/DapX lipoprotein MIM_c28970 236d806dba13acb3f8a5fad557b9174d 460 Pfam PF03929 PepSY-associated TM region 18 388 1.1E-64 T 12-10-2018 IPR005625 PepSY-associated TM protein MIM_c10330 f5e72d529bd3df3e221b19a21e2b2c41 270 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 25 238 8.8E-21 T 12-10-2018 MIM_c12950 aeab5c0514ff608cc0458832952a507d 150 Gene3D G3DSA:1.20.120.520 1 141 8.3E-10 T 12-10-2018 MIM_c12950 aeab5c0514ff608cc0458832952a507d 150 Pfam PF01814 Hemerythrin HHE cation binding domain 5 120 7.4E-15 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 MIM_c07670 b2d176e1edb426780d3fac418dbc71c6 82 SUPERFAMILY SSF56672 11 73 8.81E-10 T 12-10-2018 MIM_c37580 9b6a2aea3de1e5fe3c44d1e2c122030b 93 SMART SM00858 11 89 2.8E-6 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 MIM_c37580 9b6a2aea3de1e5fe3c44d1e2c122030b 93 Gene3D G3DSA:3.90.1210.30 4 92 9.0E-23 T 12-10-2018 MIM_c13910 ec1bfdf76d146b27c0d219af1c339473 284 Pfam PF02653 Branched-chain amino acid transport system / permease component 5 271 6.7E-45 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c34770 a6c73e9e7b99268e904bb1bba9c9b8cd 128 Pfam PF13665 Domain of unknown function (DUF4150) 10 113 1.7E-35 T 12-10-2018 IPR025425 Domain of unknown function DUF4150 MIM_c23020 3471d7500c38053e24b0a1a41a5b9d38 501 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 438 8.0E-155 T 12-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane MIM_c32590 6183bbea2972ffe11b68f03e63f780bd 357 Pfam PF00953 Glycosyl transferase family 4 65 220 1.1E-26 T 12-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 MIM_c37100 6495dcb67a3f512f01419c5bf2ab7fc7 44 Gene3D G3DSA:1.10.10.10 1 37 7.5E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MIM_c10690 e0436d2462890c0d947bd6f02feb0b1d 277 Pfam PF07120 Protein of unknown function (DUF1376) 2 87 4.6E-33 T 12-10-2018 IPR010781 Protein of unknown function DUF1376 MIM_c19480 3adf62853d8d68bc31289aff6a3768f3 370 Pfam PF00487 Fatty acid desaturase 71 331 2.6E-31 T 12-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 MIM_c39960 c277e40b4c337d00e5edce3963c9d2aa 576 Pfam PF02646 RmuC family 181 477 5.2E-90 T 12-10-2018 IPR003798 DNA recombination RmuC MIM_c18600 31a91bb2d6edd357515a356afe2fc9d3 649 Pfam PF05787 Bacterial protein of unknown function (DUF839) 197 582 1.7E-18 T 12-10-2018 IPR008557 Protein of unknown function DUF839 MIM_c15040 bffaf74bafd62e87ee93a1ad02887407 256 Pfam PF01925 Sulfite exporter TauE/SafE 12 250 3.2E-38 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MIM_c38920 d128e9fa499507acd64b280337fded61 101 Pfam PF04365 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 13 90 1.9E-16 T 12-10-2018 IPR007460 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system MIM_c24220 bdc2ff289e409e826adf7fa3717aed3c 345 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 331 7.3E-22 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MIM_c29630 03a724dba142b31e366b008cad54fecc 389 Pfam PF08907 Domain of unknown function (DUF1853) 39 330 2.0E-60 T 12-10-2018 IPR015003 Protein of unknown function DUF1853 MIM_c37980 2f26174d6e0828baba999c217bec3e0e 62 Pfam PF01679 Proteolipid membrane potential modulator 1 47 1.9E-6 T 12-10-2018 IPR000612 Proteolipid membrane potential modulator GO:0016021 MIM_c06550 86eb70a9b6e881cbbd517dc3da37bac8 891 SUPERFAMILY SSF56112 29 134 9.34E-5 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily MIM_c39270 28557efef698a629f78adf67b0755084 181 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 10 146 1.5E-21 T 12-10-2018 IPR009936 Protein of unknown function DUF1468 MIM_c02990 17c7fc2d48f86279b2e89be88e7d986d 203 Pfam PF01810 LysE type translocator 16 191 3.4E-20 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MIM_c18340 2458a6b6ebe5841bec2b32bf0025d638 604 Pfam PF04375 HemX, putative uroporphyrinogen-III C-methyltransferase 301 592 7.6E-34 T 12-10-2018 IPR007470 Putative uroporphyrinogen-III C-methyltransferase HemX MIM_c28920 78c6802f72fd657cfe07e17e1bf16ae1 299 Pfam PF12889 Protein of unknown function (DUF3829) 43 263 3.1E-18 T 12-10-2018 IPR024291 Protein of unknown function DUF3829 MIM_c17210 5cdf941b41b7ac162005f50cd73d2ab0 155 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 16 150 8.2E-22 T 12-10-2018 IPR009936 Protein of unknown function DUF1468 MIM_c23230 aad1a441a04b0a6bdbac1ca32375313d 230 Pfam PF13590 Domain of unknown function (DUF4136) 35 201 1.5E-20 T 12-10-2018 IPR025411 Domain of unknown function DUF4136 MIM_c33980 b1b816a4e03f85d824f7010f3fac4ef4 326 Pfam PF13503 Domain of unknown function (DUF4123) 29 122 7.2E-6 T 12-10-2018 IPR025391 Domain of unknown function DUF4123