locus-tag	class	description
EYZ66_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EYZ66_00010	COG0592	DNA-directed DNA polymerase activity
EYZ66_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EYZ66_00020	COG0187	DNA topoisomerase II activity
EYZ66_00025	COG0751	glycine-tRNA ligase activity
EYZ66_00030	COG0752	glycyl-tRNA synthetase alpha subunit
EYZ66_00040	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EYZ66_00045	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EYZ66_00050	COG0569	domain protein
EYZ66_00055	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EYZ66_00060	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EYZ66_00065	COG0242	peptide deformylase activity
EYZ66_00075	COG0758	DNA mediated transformation
EYZ66_00085	COG0009	L-threonylcarbamoyladenylate synthase
EYZ66_00090	COG0408	coproporphyrinogen oxidase activity
EYZ66_00095	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EYZ66_00100	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EYZ66_00110	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EYZ66_00115	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EYZ66_00125	COG1845	cytochrome c oxidase, subunit III
EYZ66_00145	COG0109	protoheme IX farnesyltransferase activity
EYZ66_00165	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EYZ66_00200	COG2814	Major facilitator Superfamily
EYZ66_00205	COG1522	sequence-specific DNA binding
EYZ66_00210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EYZ66_00215	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EYZ66_00225	COG0129	dihydroxy-acid dehydratase activity
EYZ66_00230	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EYZ66_00230	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EYZ66_00235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYZ66_00240	COG0306	phosphate transporter
EYZ66_00245	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EYZ66_00255	COG2267	carboxylic ester hydrolase activity
EYZ66_00280	COG1519	Transferase
EYZ66_00285	COG1538	Outer membrane efflux protein
EYZ66_00295	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EYZ66_00320	COG0671	phosphoesterase, PA-phosphatase related
EYZ66_00325	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EYZ66_00325	COG0519	Catalyzes the synthesis of GMP from XMP
EYZ66_00330	COG0346	lactoylglutathione lyase activity
EYZ66_00335	COG3279	Response regulator of the LytR AlgR family
EYZ66_00340	COG3275	phosphorelay sensor kinase activity
EYZ66_00345	COG0456	acetyltransferase
EYZ66_00370	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EYZ66_00390	COG4206	TonB-dependent receptor
EYZ66_00405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYZ66_00420	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EYZ66_00425	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EYZ66_00430	COG0154	amidase activity
EYZ66_00435	COG0179	Fumarylacetoacetate (FAA) hydrolase
EYZ66_00455	COG0745	RESPONSE REGULATOR receiver
EYZ66_00460	COG2205	protein histidine kinase activity
EYZ66_00470	COG0651	ATP synthesis coupled electron transport
EYZ66_00480	COG0651	ATP synthesis coupled electron transport
EYZ66_00485	COG0651	ATP synthesis coupled electron transport
EYZ66_00490	COG1006	Multisubunit Na H antiporter MnhC subunit
EYZ66_00500	COG1320	monovalent cation:proton antiporter activity
EYZ66_00510	COG1863	multisubunit Na H antiporter MnhE subunit
EYZ66_00515	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_00535	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EYZ66_00540	COG0358	DNA primase activity
EYZ66_00550	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EYZ66_00555	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EYZ66_00570	COG0617	tRNA 3'-terminal CCA addition
EYZ66_00575	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EYZ66_00580	COG2967	ApaG domain
EYZ66_00585	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EYZ66_00590	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EYZ66_00595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EYZ66_00600	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EYZ66_00605	COG3178	'Phosphotransferase
EYZ66_00615	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EYZ66_00625	COG0512	Glutamine amidotransferase of anthranilate synthase
EYZ66_00630	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EYZ66_00635	COG0134	indole-3-glycerol-phosphate synthase activity
EYZ66_00645	COG1765	OsmC-like protein
EYZ66_00650	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
EYZ66_00655	COG0151	Belongs to the GarS family
EYZ66_00675	COG2264	protein methyltransferase activity
EYZ66_00685	COG0511	ligase activity, forming carbon-carbon bonds
EYZ66_00690	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EYZ66_00715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYZ66_00720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EYZ66_00730	COG1119	ATPase activity
EYZ66_00750	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EYZ66_00755	COG1981	membrane
EYZ66_00765	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EYZ66_00780	COG0739	heme binding
EYZ66_00825	COG2433	Pfam Transposase IS66
EYZ66_00850	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_00870	COG4191	Histidine kinase
EYZ66_00890	COG3300	MHYT domain
EYZ66_00890	COG5001	Diguanylate cyclase
EYZ66_00905	COG2366	antibiotic biosynthetic process
EYZ66_00910	COG5505	Protein of unknown function (DUF819)
EYZ66_00915	COG1902	pentaerythritol trinitrate reductase activity
EYZ66_00925	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EYZ66_00940	COG0583	DNA-binding transcription factor activity
EYZ66_00945	COG1476	TRANSCRIPTIONal
EYZ66_00970	COG1566	PFAM secretion protein HlyD family protein
EYZ66_00980	COG0393	Putative heavy-metal-binding
EYZ66_01000	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EYZ66_01005	COG0783	Belongs to the Dps family
EYZ66_01015	COG3300	MHYT domain
EYZ66_01015	COG5001	Diguanylate cyclase
EYZ66_01020	COG1611	Belongs to the LOG family
EYZ66_01025	COG1301	dicarboxylic acid transport
EYZ66_01030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYZ66_01040	COG1228	amidohydrolase
EYZ66_01045	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EYZ66_01050	COG4783	chaperone-mediated protein folding
EYZ66_01090	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EYZ66_01130	COG0405	Gamma-glutamyltransferase
EYZ66_01135	COG0259	pyridoxamine-phosphate oxidase activity
EYZ66_01160	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EYZ66_01165	COG1162	GTPase activity
EYZ66_01170	COG0688	phosphatidylethanolamine metabolic process
EYZ66_01190	COG0243	molybdopterin cofactor binding
EYZ66_01210	COG2175	clavaminate synthase activity
EYZ66_01225	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EYZ66_01235	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EYZ66_01245	COG1454	alcohol dehydrogenase
EYZ66_01265	COG1882	Formate acetyltransferase
EYZ66_01275	COG1882	Formate acetyltransferase
EYZ66_01280	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EYZ66_01290	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EYZ66_01295	COG2379	hydroxypyruvate reductase
EYZ66_01300	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EYZ66_01310	COG2207	Transcriptional regulator
EYZ66_01315	COG2211	Major facilitator Superfamily
EYZ66_01335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EYZ66_01345	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EYZ66_01350	COG1882	Formate acetyltransferase
EYZ66_01360	COG2186	Transcriptional regulator
EYZ66_01365	COG3119	arylsulfatase activity
EYZ66_01380	COG2211	Major facilitator Superfamily
EYZ66_01400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EYZ66_01410	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EYZ66_01415	COG1882	Formate acetyltransferase
EYZ66_01425	COG2186	Transcriptional regulator
EYZ66_01440	COG2992	FlgJ-related protein
EYZ66_01450	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EYZ66_01455	COG0557	exoribonuclease II activity
EYZ66_01465	COG1312	Catalyzes the dehydration of D-mannonate
EYZ66_01470	COG0246	Mannitol dehydrogenase
EYZ66_01495	COG1024	Enoyl-CoA hydratase
EYZ66_01500	COG1024	Enoyl-CoA hydratase
EYZ66_01520	COG0730	response to heat
EYZ66_01565	COG2133	pyrroloquinoline quinone binding
EYZ66_01580	COG1022	Amp-dependent synthetase and ligase
EYZ66_01585	COG1454	alcohol dehydrogenase
EYZ66_01590	COG0657	acetylesterase activity
EYZ66_01615	COG1960	acyl-CoA dehydrogenase activity
EYZ66_01635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYZ66_01640	COG0601	transmembrane transport
EYZ66_01670	COG1505	serine-type exopeptidase activity
EYZ66_01675	COG0501	Belongs to the peptidase M48B family
EYZ66_01680	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EYZ66_01695	COG1011	Hydrolase
EYZ66_01705	COG2918	glutathione biosynthetic process
EYZ66_01710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYZ66_01715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYZ66_01730	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EYZ66_01735	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EYZ66_01745	COG0471	metal ion transport
EYZ66_01765	COG2207	Transcriptional regulator
EYZ66_01770	COG1704	LemA family
EYZ66_01800	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EYZ66_01820	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EYZ66_01825	COG0081	regulation of translation
EYZ66_01830	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EYZ66_01835	COG0222	ribosome binding
EYZ66_01840	COG0085	RNA polymerase activity
EYZ66_01845	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EYZ66_01850	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EYZ66_01855	COG0049	tRNA binding
EYZ66_01860	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EYZ66_01865	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EYZ66_01870	COG0697	spore germination
EYZ66_01880	COG0051	transcription antitermination factor activity, RNA binding
EYZ66_01885	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EYZ66_01890	COG0088	Forms part of the polypeptide exit tunnel
EYZ66_01895	COG0089	rRNA binding
EYZ66_01900	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EYZ66_01905	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EYZ66_01910	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EYZ66_01915	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EYZ66_01920	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EYZ66_01925	COG0255	Belongs to the universal ribosomal protein uL29 family
EYZ66_01930	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EYZ66_01935	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EYZ66_01940	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EYZ66_01945	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EYZ66_01950	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EYZ66_01955	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EYZ66_01960	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EYZ66_01965	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EYZ66_01970	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EYZ66_01975	COG1841	ribosomal large subunit assembly
EYZ66_01980	COG0200	Binds to the 23S rRNA
EYZ66_01995	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EYZ66_02000	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EYZ66_02005	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EYZ66_02010	COG0202	RNA polymerase activity
EYZ66_02025	COG2814	Major facilitator Superfamily
EYZ66_02030	COG0629	single-stranded DNA binding
EYZ66_02040	COG0521	Mo-molybdopterin cofactor biosynthetic process
EYZ66_02055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EYZ66_02070	COG0142	geranyltranstransferase activity
EYZ66_02075	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EYZ66_02080	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EYZ66_02085	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EYZ66_02090	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EYZ66_02095	COG0268	Binds directly to 16S ribosomal RNA
EYZ66_02100	COG2365	Tyrosine phosphatase family
EYZ66_02120	COG1199	ATP-dependent helicase activity
EYZ66_02130	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EYZ66_02140	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EYZ66_02145	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EYZ66_02150	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EYZ66_02155	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EYZ66_02160	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EYZ66_02170	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EYZ66_02175	COG0768	penicillin binding
EYZ66_02180	COG0772	Belongs to the SEDS family
EYZ66_02185	COG2951	lytic endotransglycosylase activity
EYZ66_02195	COG1686	Belongs to the peptidase S11 family
EYZ66_02200	COG2921	Belongs to the UPF0250 family
EYZ66_02205	COG0321	lipoyl(octanoyl) transferase activity
EYZ66_02210	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EYZ66_02220	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EYZ66_02225	COG0386	Belongs to the glutathione peroxidase family
EYZ66_02235	COG3021	interspecies interaction between organisms
EYZ66_02240	COG0174	glutamine synthetase
EYZ66_02250	COG0442	prolyl-tRNA aminoacylation
EYZ66_02260	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EYZ66_02265	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EYZ66_02270	COG0632	four-way junction helicase activity
EYZ66_02275	COG2255	four-way junction helicase activity
EYZ66_02280	COG0824	Thioesterase
EYZ66_02300	COG0823	Involved in the tonB-independent uptake of proteins
EYZ66_02310	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EYZ66_02315	COG0602	queuosine metabolic process
EYZ66_02320	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EYZ66_02340	COG0318	PFAM AMP-dependent synthetase and ligase
EYZ66_02345	COG1940	carbohydrate kinase activity
EYZ66_02355	COG4774	siderophore transport
EYZ66_02380	COG0243	molybdopterin cofactor binding
EYZ66_02395	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EYZ66_02400	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EYZ66_02405	COG1722	exodeoxyribonuclease VII activity
EYZ66_02410	COG0142	geranyltranstransferase activity
EYZ66_02415	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EYZ66_02425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EYZ66_02430	COG3976	FMN-binding domain protein
EYZ66_02430	COG1053	succinate dehydrogenase
EYZ66_02440	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
EYZ66_02445	COG1435	thymidine kinase activity
EYZ66_02450	COG2175	clavaminate synthase activity
EYZ66_02465	COG0598	Magnesium transport protein CorA
EYZ66_02470	COG0513	Belongs to the DEAD box helicase family
EYZ66_02480	COG5001	Diguanylate cyclase
EYZ66_02480	COG4251	negative regulation of phosphorylation
EYZ66_02480	COG3706	GGDEF domain
EYZ66_02480	COG2203	Gaf domain
EYZ66_02490	COG0625	glutathione transferase activity
EYZ66_02500	COG2133	pyrroloquinoline quinone binding
EYZ66_02510	COG4771	TonB-dependent receptor
EYZ66_02680	COG4569	acetaldehyde dehydrogenase (acetylating) activity
EYZ66_02685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EYZ66_02710	COG2267	carboxylic ester hydrolase activity
EYZ66_02735	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EYZ66_02755	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EYZ66_02755	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EYZ66_02760	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EYZ66_02770	COG2072	flavoprotein involved in K transport
EYZ66_02785	COG1960	acyl-CoA dehydrogenase activity
EYZ66_02800	COG1960	acyl-CoA dehydrogenase activity
EYZ66_02815	COG1960	acyl-CoA dehydrogenase activity
EYZ66_02825	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_02830	COG0183	Belongs to the thiolase family
EYZ66_02840	COG1454	alcohol dehydrogenase
EYZ66_02845	COG0824	Thioesterase
EYZ66_02860	COG0505	Belongs to the CarA family
EYZ66_02870	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EYZ66_02880	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EYZ66_02885	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EYZ66_02890	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EYZ66_02895	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EYZ66_02900	COG0149	triose-phosphate isomerase activity
EYZ66_02925	COG0300	oxidoreductase activity
EYZ66_02940	COG4774	siderophore transport
EYZ66_02955	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EYZ66_02970	COG0195	Participates in both transcription termination and antitermination
EYZ66_02975	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EYZ66_02980	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EYZ66_02985	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EYZ66_02990	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EYZ66_02995	COG1185	polyribonucleotide nucleotidyltransferase activity
EYZ66_03000	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EYZ66_03005	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EYZ66_03010	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EYZ66_03015	COG1428	Deoxynucleoside kinase
EYZ66_03025	COG0617	tRNA 3'-terminal CCA addition
EYZ66_03030	COG2204	response regulator
EYZ66_03035	COG3852	Histidine kinase
EYZ66_03040	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EYZ66_03050	COG1876	peptidase activity
EYZ66_03060	COG0205	6-phosphofructokinase activity
EYZ66_03065	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EYZ66_03090	COG0418	dihydroorotase activity
EYZ66_03095	COG0137	argininosuccinate synthase activity
EYZ66_03105	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EYZ66_03110	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_03125	COG0513	Belongs to the DEAD box helicase family
EYZ66_03135	COG4948	Mandelate Racemase Muconate Lactonizing
EYZ66_03145	COG4948	Mandelate Racemase Muconate Lactonizing
EYZ66_03205	COG0557	exoribonuclease II activity
EYZ66_03210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYZ66_03220	COG2433	Pfam Transposase IS66
EYZ66_03280	COG1012	belongs to the aldehyde dehydrogenase family
EYZ66_03300	COG4172	Belongs to the ABC transporter superfamily
EYZ66_03305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYZ66_03310	COG0601	transmembrane transport
EYZ66_03320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYZ66_03335	COG0473	3-isopropylmalate dehydrogenase activity
EYZ66_03340	COG1012	belongs to the aldehyde dehydrogenase family
EYZ66_03355	COG1522	sequence-specific DNA binding
EYZ66_03365	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYZ66_03385	COG0360	Binds together with S18 to 16S ribosomal RNA
EYZ66_03390	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EYZ66_03400	COG0359	binds to the 23S rRNA
EYZ66_03405	COG0305	Participates in initiation and elongation during chromosome replication
EYZ66_03420	COG3119	arylsulfatase activity
EYZ66_03425	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_03430	COG1234	tRNA 3'-trailer cleavage
EYZ66_03465	COG1309	transcriptional regulator
EYZ66_03480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYZ66_03485	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EYZ66_03515	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EYZ66_03525	COG1960	acyl-CoA dehydrogenase activity
EYZ66_03530	COG1960	acyl-CoA dehydrogenase activity
EYZ66_03535	COG1960	acyl-CoA dehydrogenase activity
EYZ66_03545	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EYZ66_03550	COG3046	protein related to deoxyribodipyrimidine photolyase
EYZ66_03560	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EYZ66_03575	COG4753	response regulator
EYZ66_03575	COG2207	Transcriptional regulator
EYZ66_03580	COG4771	TonB-dependent receptor
EYZ66_03600	COG0415	Belongs to the DNA photolyase family
EYZ66_03605	COG1902	pentaerythritol trinitrate reductase activity
EYZ66_03610	COG0415	Belongs to the DNA photolyase family
EYZ66_03620	COG0247	lactate metabolic process
EYZ66_03625	COG1592	Rubrerythrin
EYZ66_03630	COG0583	DNA-binding transcription factor activity
EYZ66_03635	COG2183	response to ionizing radiation
EYZ66_03640	COG0628	permease
EYZ66_03645	COG2391	methyltransferase activity
EYZ66_03650	COG2391	methyltransferase activity
EYZ66_03655	COG0339	signal peptide processing
EYZ66_03660	COG0686	Belongs to the AlaDH PNT family
EYZ66_03670	COG1902	pentaerythritol trinitrate reductase activity
EYZ66_03670	COG0446	pyridine nucleotide-disulphide oxidoreductase
EYZ66_03690	COG1960	acyl-CoA dehydrogenase activity
EYZ66_03695	COG0668	transmembrane transport
EYZ66_03705	COG2957	Belongs to the agmatine deiminase family
EYZ66_03710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYZ66_03720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EYZ66_03725	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EYZ66_03740	COG3706	GGDEF domain
EYZ66_03740	COG4251	negative regulation of phosphorylation
EYZ66_03740	COG2203	Gaf domain
EYZ66_03740	COG5001	Diguanylate cyclase
EYZ66_03765	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EYZ66_03775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYZ66_03785	COG1609	Transcriptional regulator
EYZ66_03790	COG2721	sulfolactate sulfo-lyase activity
EYZ66_03800	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EYZ66_03805	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EYZ66_03810	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_03815	COG0246	Mannitol dehydrogenase
EYZ66_03820	COG2755	lipolytic protein G-D-S-L family
EYZ66_03835	COG4677	pectinesterase activity
EYZ66_03855	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EYZ66_03870	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EYZ66_03880	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EYZ66_03890	COG2046	Belongs to the sulfate adenylyltransferase family
EYZ66_03895	COG0529	Catalyzes the synthesis of activated sulfate
EYZ66_03900	COG0583	DNA-binding transcription factor activity
EYZ66_03910	COG1136	(ABC) transporter
EYZ66_03915	COG4591	ABC-type transport system involved in lipoprotein release permease component
EYZ66_03940	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_03945	COG0183	Belongs to the thiolase family
EYZ66_03950	COG0183	Belongs to the thiolase family
EYZ66_03970	COG2264	protein methyltransferase activity
EYZ66_04005	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EYZ66_04015	COG2205	protein histidine kinase activity
EYZ66_04020	COG0745	RESPONSE REGULATOR receiver
EYZ66_04030	COG2304	oxidoreductase activity
EYZ66_04040	COG0330	HflC and HflK could
EYZ66_04060	COG0676	glucose-6-phosphate 1-epimerase activity
EYZ66_04090	COG0798	PFAM Bile acid sodium symporter
EYZ66_04105	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EYZ66_04110	COG3268	Saccharopine dehydrogenase
EYZ66_04120	COG1280	lysine exporter protein (LysE YggA)
EYZ66_04130	COG2814	Major facilitator Superfamily
EYZ66_04135	COG2267	carboxylic ester hydrolase activity
EYZ66_04140	COG4771	TonB-dependent receptor
EYZ66_04150	COG0582	viral genome integration into host DNA
EYZ66_04180	COG1408	metallophosphoesterase
EYZ66_04315	COG0318	PFAM AMP-dependent synthetase and ligase
EYZ66_04320	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_04330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EYZ66_04330	COG2010	Cytochrome c
EYZ66_04340	COG0435	Glutathione S-transferase
EYZ66_04360	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EYZ66_04365	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EYZ66_04370	COG0733	neurotransmitter:sodium symporter activity
EYZ66_04380	COG2914	Belongs to the UPF0125 (RnfH) family
EYZ66_04395	COG0497	DNA recombination
EYZ66_04400	COG1420	regulation of RNA biosynthetic process
EYZ66_04405	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EYZ66_04410	COG0443	Heat shock 70 kDa protein
EYZ66_04415	COG0484	heat shock protein binding
EYZ66_04420	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EYZ66_04425	COG3118	belongs to the thioredoxin family
EYZ66_04435	COG1960	acyl-CoA dehydrogenase activity
EYZ66_04450	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
EYZ66_04465	COG1946	Acyl-CoA thioesterase
EYZ66_04485	COG2205	protein histidine kinase activity
EYZ66_04485	COG5002	protein histidine kinase activity
EYZ66_04485	COG0784	Response regulator, receiver
EYZ66_04495	COG1404	Belongs to the peptidase S8 family
EYZ66_04505	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EYZ66_04515	COG0425	Belongs to the sulfur carrier protein TusA family
EYZ66_04535	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYZ66_04545	COG3769	mannosylglycerate metabolic process
EYZ66_04550	COG1215	transferase activity, transferring glycosyl groups
EYZ66_04570	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EYZ66_04580	COG0318	PFAM AMP-dependent synthetase and ligase
EYZ66_04590	COG0459	protein refolding
EYZ66_04595	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EYZ66_04600	COG3030	protein affecting phage T7 exclusion by the F plasmid
EYZ66_04605	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_04610	COG3123	guanosine phosphorylase activity
EYZ66_04615	COG2211	Major facilitator Superfamily
EYZ66_04640	COG2925	Exonuclease
EYZ66_04645	COG0540	Belongs to the ATCase OTCase family
EYZ66_04650	COG0494	nUDIX hydrolase
EYZ66_04660	COG0196	riboflavin kinase activity
EYZ66_04665	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EYZ66_04675	COG1047	Peptidyl-prolyl cis-trans
EYZ66_04685	COG4970	Tfp pilus assembly protein FimT
EYZ66_04720	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EYZ66_04720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYZ66_04750	COG0028	Belongs to the TPP enzyme family
EYZ66_04760	COG2801	Transposase and inactivated derivatives
EYZ66_04765	COG2963	transposase activity
EYZ66_04775	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EYZ66_04785	COG1183	phosphatidylcholine synthase activity
EYZ66_04795	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
EYZ66_04825	COG4372	Transposase
EYZ66_04840	COG2433	Pfam Transposase IS66
EYZ66_04850	COG0450	alkyl hydroperoxide reductase
EYZ66_04855	COG0300	oxidoreductase activity
EYZ66_04865	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYZ66_04870	COG1304	FMN binding
EYZ66_04875	COG0028	Belongs to the TPP enzyme family
EYZ66_04880	COG0129	dihydroxy-acid dehydratase activity
EYZ66_04890	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
EYZ66_04895	COG0709	Synthesizes selenophosphate from selenide and ATP
EYZ66_04910	COG0456	acetyltransferase
EYZ66_04920	COG4660	Part of a membrane complex involved in electron transport
EYZ66_04925	COG4659	FMN binding
EYZ66_04930	COG4658	electron transport chain
EYZ66_04940	COG2878	Part of a membrane complex involved in electron transport
EYZ66_04945	COG4657	Part of a membrane complex involved in electron transport
EYZ66_04950	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYZ66_04950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYZ66_04955	COG0489	protein tyrosine kinase activity
EYZ66_04960	COG0717	Belongs to the dCTP deaminase family
EYZ66_04970	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EYZ66_04975	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EYZ66_05010	COG1393	Belongs to the ArsC family
EYZ66_05030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYZ66_05040	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EYZ66_05055	COG0742	ribosomal rna small subunit methyltransferase
EYZ66_05065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYZ66_05075	COG1393	Belongs to the ArsC family
EYZ66_05080	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EYZ66_05090	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EYZ66_05095	COG0024	Methionine aminopeptidase
EYZ66_05100	COG0052	Belongs to the universal ribosomal protein uS2 family
EYZ66_05105	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EYZ66_05110	COG0528	UMP kinase activity
EYZ66_05115	COG0233	cytoplasmic translational termination
EYZ66_05120	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EYZ66_05125	COG0575	Belongs to the CDS family
EYZ66_05130	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EYZ66_05150	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYZ66_05155	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EYZ66_05160	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYZ66_05165	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYZ66_05170	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EYZ66_05180	COG3300	MHYT domain
EYZ66_05180	COG5001	Diguanylate cyclase
EYZ66_05200	COG0183	Belongs to the thiolase family
EYZ66_05235	COG0720	synthase
EYZ66_05260	COG4771	TonB-dependent receptor
EYZ66_05265	COG2814	Major facilitator Superfamily
EYZ66_05275	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EYZ66_05280	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EYZ66_05305	COG4948	Mandelate Racemase Muconate Lactonizing
EYZ66_05335	COG0004	ammonium transporteR
EYZ66_05350	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EYZ66_05375	COG0308	aminopeptidase N
EYZ66_05405	COG0714	Associated with various cellular activities
EYZ66_05415	COG0167	dihydroorotate dehydrogenase activity
EYZ66_05420	COG3130	regulation of translation
EYZ66_05430	COG0457	Tetratricopeptide repeat
EYZ66_05435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EYZ66_05440	COG1671	Belongs to the UPF0178 family
EYZ66_05470	COG1090	epimerase
EYZ66_05475	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EYZ66_05480	COG4221	oxidoreductase activity
EYZ66_05485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EYZ66_05500	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
EYZ66_05505	COG1335	isochorismatase
EYZ66_05510	COG3829	transcription factor binding
EYZ66_05550	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EYZ66_05560	COG0674	pyruvate-flavodoxin oxidoreductase activity
EYZ66_05560	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EYZ66_05570	COG2897	thiosulfate sulfurtransferase activity
EYZ66_05580	COG0023	Translation Initiation Factor
EYZ66_05590	COG1960	acyl-CoA dehydrogenase activity
EYZ66_05605	COG0596	Alpha beta hydrolase
EYZ66_05620	COG0252	asparaginase activity
EYZ66_05640	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EYZ66_05640	COG0116	Belongs to the methyltransferase superfamily
EYZ66_05650	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EYZ66_05655	COG0066	3-isopropylmalate dehydratase activity
EYZ66_05660	COG0473	3-isopropylmalate dehydrogenase activity
EYZ66_05665	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EYZ66_05680	COG0135	phosphoribosylanthranilate isomerase activity
EYZ66_05690	COG0159	tryptophan synthase activity
EYZ66_05695	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EYZ66_05700	COG0285	dihydrofolate synthase activity
EYZ66_05710	COG1286	toxin biosynthetic process
EYZ66_05725	COG0714	Associated with various cellular activities
EYZ66_05755	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYZ66_05765	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EYZ66_05770	COG0215	cysteine-tRNA ligase activity
EYZ66_05775	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EYZ66_05810	COG0427	acetyl-CoA hydrolase
EYZ66_05830	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_05850	COG1022	Amp-dependent synthetase and ligase
EYZ66_05875	COG4633	Protein conserved in bacteria
EYZ66_05895	COG3268	Saccharopine dehydrogenase
EYZ66_05900	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_05905	COG3706	GGDEF domain
EYZ66_05925	COG0633	Ferredoxin
EYZ66_05955	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EYZ66_05960	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EYZ66_05970	COG3100	YcgL domain-containing protein
EYZ66_05975	COG2983	Belongs to the UPF0260 family
EYZ66_05990	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EYZ66_06000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYZ66_06010	COG0589	response to stress
EYZ66_06035	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EYZ66_06040	COG0668	transmembrane transport
EYZ66_06050	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EYZ66_06060	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EYZ66_06065	COG1805	sodium ion transport
EYZ66_06080	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EYZ66_06090	COG1477	protein flavinylation
EYZ66_06105	COG1136	(ABC) transporter
EYZ66_06125	COG0811	peptide transport
EYZ66_06135	COG1663	tetraacyldisaccharide 4'-kinase activity
EYZ66_06140	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EYZ66_06145	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EYZ66_06195	COG1476	TRANSCRIPTIONal
EYZ66_06210	COG0585	pseudouridine synthase activity
EYZ66_06215	COG1024	Enoyl-CoA hydratase
EYZ66_06235	COG1595	DNA-templated transcription, initiation
EYZ66_06245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EYZ66_06260	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_06265	COG0583	DNA-binding transcription factor activity
EYZ66_06270	COG0457	Tetratricopeptide repeat
EYZ66_06290	COG0436	Aminotransferase
EYZ66_06335	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EYZ66_06345	COG2271	Major facilitator Superfamily
EYZ66_06350	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_06355	COG2801	Transposase and inactivated derivatives
EYZ66_06360	COG2963	transposase activity
EYZ66_06365	COG1960	acyl-CoA dehydrogenase activity
EYZ66_06375	COG2030	dehydratase
EYZ66_06380	COG1960	acyl-CoA dehydrogenase activity
EYZ66_06395	COG0446	pyridine nucleotide-disulphide oxidoreductase
EYZ66_06395	COG1902	pentaerythritol trinitrate reductase activity
EYZ66_06415	COG0659	secondary active sulfate transmembrane transporter activity
EYZ66_06420	COG0733	neurotransmitter:sodium symporter activity
EYZ66_06430	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EYZ66_06435	COG0708	Exodeoxyribonuclease III
EYZ66_06440	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EYZ66_06445	COG0584	glycerophosphoryl diester phosphodiesterase
EYZ66_06465	COG0183	Belongs to the thiolase family
EYZ66_06470	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_06515	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EYZ66_06530	COG0670	Belongs to the BI1 family
EYZ66_06560	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EYZ66_06565	COG0277	FAD linked oxidase domain protein
EYZ66_06570	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EYZ66_06595	COG3551	Protein conserved in bacteria
EYZ66_06640	COG1530	ribonuclease E activity
EYZ66_06650	COG0546	phosphoglycolate phosphatase activity
EYZ66_06655	COG0424	maF-like protein
EYZ66_06665	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EYZ66_06670	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EYZ66_06680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYZ66_06685	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EYZ66_06690	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EYZ66_06695	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EYZ66_06700	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EYZ66_06715	COG3291	Pkd domain containing protein
EYZ66_06715	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EYZ66_06725	COG0544	peptidyl-prolyl cis-trans isomerase activity
EYZ66_06730	COG0740	serine-type endopeptidase activity
EYZ66_06735	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EYZ66_06740	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EYZ66_06750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EYZ66_06755	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYZ66_06780	COG4651	solute:proton antiporter activity
EYZ66_06780	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EYZ66_06805	COG0316	Belongs to the HesB IscA family
EYZ66_06805	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EYZ66_06820	COG1074	ATP-dependent DNA helicase activity
EYZ66_06825	COG0741	lytic transglycosylase activity
EYZ66_06825	COG1388	LysM domain
EYZ66_06830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYZ66_06840	COG0328	RNA-DNA hybrid ribonuclease activity
EYZ66_06850	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EYZ66_06855	COG2816	NAD+ diphosphatase activity
EYZ66_06860	COG0616	signal peptide processing
EYZ66_06880	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_06890	COG0778	Nitroreductase
EYZ66_06925	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EYZ66_06925	COG1648	precorrin-2 dehydrogenase activity
EYZ66_06930	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EYZ66_06935	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EYZ66_06950	COG0492	ferredoxin-NADP+ reductase activity
EYZ66_06955	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EYZ66_06960	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EYZ66_06965	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EYZ66_06970	COG0542	response to heat
EYZ66_06975	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EYZ66_06995	COG0482	sulfurtransferase activity
EYZ66_07000	COG2915	High frequency lysogenization protein hflD homolog
EYZ66_07020	COG1703	isobutyryl-CoA mutase activity
EYZ66_07025	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EYZ66_07025	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EYZ66_07030	COG0346	lactoylglutathione lyase activity
EYZ66_07040	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EYZ66_07055	COG0583	DNA-binding transcription factor activity
EYZ66_07065	COG1862	Preprotein translocase
EYZ66_07075	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EYZ66_07095	COG2814	Major facilitator Superfamily
EYZ66_07100	COG0300	oxidoreductase activity
EYZ66_07125	COG0217	transcriptional regulatory protein
EYZ66_07130	COG1785	Belongs to the alkaline phosphatase family
EYZ66_07135	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_07145	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EYZ66_07150	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EYZ66_07155	COG2194	sulfuric ester hydrolase activity
EYZ66_07160	COG2824	Alkylphosphonate utilization operon protein PhnA
EYZ66_07170	COG0842	Transport permease protein
EYZ66_07175	COG1131	(ABC) transporter
EYZ66_07210	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EYZ66_07215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYZ66_07220	COG3101	peptidyl-lysine hydroxylation
EYZ66_07225	COG0425	Belongs to the sulfur carrier protein TusA family
EYZ66_07250	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EYZ66_07260	COG0302	gtp cyclohydrolase
EYZ66_07270	COG0326	Molecular chaperone. Has ATPase activity
EYZ66_07280	COG0045	succinate-CoA ligase (ADP-forming) activity
EYZ66_07305	COG1053	succinate dehydrogenase
EYZ66_07310	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EYZ66_07315	COG2009	succinate dehydrogenase
EYZ66_07330	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EYZ66_07335	COG0704	Plays a role in the regulation of phosphate uptake
EYZ66_07340	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EYZ66_07345	COG0581	inorganic phosphate transmembrane transporter activity
EYZ66_07350	COG0573	inorganic phosphate transmembrane transporter activity
EYZ66_07375	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EYZ66_07380	COG3115	cell septum assembly
EYZ66_07410	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EYZ66_07430	COG4133	protoheme IX ABC transporter activity
EYZ66_07435	COG0037	tRNA processing
EYZ66_07440	COG0039	L-malate dehydrogenase activity
EYZ66_07445	COG1309	transcriptional regulator
EYZ66_07450	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EYZ66_07455	COG4181	ATPase activity
EYZ66_07465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EYZ66_07475	COG1566	PFAM secretion protein HlyD family protein
EYZ66_07495	COG0534	Mate efflux family protein
EYZ66_07500	COG1668	transmembrane transport
EYZ66_07505	COG4555	ABC transporter
EYZ66_07520	COG2267	carboxylic ester hydrolase activity
EYZ66_07525	COG1228	amidohydrolase
EYZ66_07560	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EYZ66_07575	COG1362	aminopeptidase activity
EYZ66_07580	COG2084	Dehydrogenase
EYZ66_07585	COG1968	undecaprenyl-diphosphatase activity
EYZ66_07595	COG0746	molybdenum cofactor guanylyltransferase activity
EYZ66_07600	COG0314	molybdopterin synthase activity
EYZ66_07610	COG0315	cyclic pyranopterin monophosphate synthase activity
EYZ66_07615	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EYZ66_07620	COG0563	adenylate kinase activity
EYZ66_07625	COG3956	TIGRFAM MazG family protein
EYZ66_07630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EYZ66_07640	COG0736	holo-[acyl-carrier-protein] synthase activity
EYZ66_07645	COG1381	Involved in DNA repair and RecF pathway recombination
EYZ66_07655	COG0571	ribonuclease III activity
EYZ66_07660	COG0681	Belongs to the peptidase S26 family
EYZ66_07665	COG0481	GTPase activity
EYZ66_07670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYZ66_07700	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EYZ66_07715	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EYZ66_07720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EYZ66_07730	COG3278	Belongs to the heme-copper respiratory oxidase family
EYZ66_07745	COG2010	Cytochrome c
EYZ66_07775	COG3047	cAMP biosynthetic process
EYZ66_07780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EYZ66_07790	COG1054	Belongs to the UPF0176 family
EYZ66_07795	COG0271	Belongs to the BolA IbaG family
EYZ66_07805	COG0642	Histidine kinase
EYZ66_07805	COG3850	Histidine kinase
EYZ66_07810	COG0745	RESPONSE REGULATOR receiver
EYZ66_07820	COG0795	lipopolysaccharide-transporting ATPase activity
EYZ66_07825	COG0795	lipopolysaccharide-transporting ATPase activity
EYZ66_07830	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EYZ66_07840	COG0525	valine-tRNA ligase activity
EYZ66_07845	COG1278	Cold shock
EYZ66_07850	COG1278	Cold shock
EYZ66_07855	COG0084	hydrolase, TatD family'
EYZ66_07870	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EYZ66_07875	COG1024	Enoyl-CoA hydratase
EYZ66_07885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EYZ66_07905	COG0318	PFAM AMP-dependent synthetase and ligase
EYZ66_07925	COG4336	lyase activity
EYZ66_07930	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EYZ66_07945	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EYZ66_07955	COG3267	Type II secretory pathway component ExeA
EYZ66_07955	COG3409	Peptidoglycan-binding domain 1 protein
EYZ66_07975	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EYZ66_07985	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EYZ66_08005	COG5002	protein histidine kinase activity
EYZ66_08020	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EYZ66_08040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYZ66_08045	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EYZ66_08050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EYZ66_08055	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EYZ66_08075	COG1131	(ABC) transporter
EYZ66_08090	COG1160	GTP binding
EYZ66_08100	COG2976	Protein conserved in bacteria
EYZ66_08105	COG0124	histidyl-tRNA synthetase
EYZ66_08110	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EYZ66_08120	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EYZ66_08125	COG0105	UTP biosynthetic process
EYZ66_08145	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EYZ66_08160	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EYZ66_08170	COG0166	Belongs to the GPI family
EYZ66_08175	COG0616	signal peptide processing
EYZ66_08220	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EYZ66_08245	COG1024	Enoyl-CoA hydratase
EYZ66_08300	COG0673	inositol 2-dehydrogenase activity
EYZ66_08315	COG2226	methyltransferase
EYZ66_08320	COG1024	Enoyl-CoA hydratase
EYZ66_08325	COG1012	belongs to the aldehyde dehydrogenase family
EYZ66_08340	COG2175	clavaminate synthase activity
EYZ66_08345	COG0583	DNA-binding transcription factor activity
EYZ66_08350	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EYZ66_08355	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EYZ66_08360	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EYZ66_08385	COG0251	oxidation-reduction process
EYZ66_08395	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EYZ66_08415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYZ66_08430	COG3328	transposase activity
EYZ66_08465	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_08470	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EYZ66_08475	COG3959	Transketolase, thiamine diphosphate binding domain
EYZ66_08485	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_08495	COG0604	alcohol dehydrogenase
EYZ66_08525	COG2304	oxidoreductase activity
EYZ66_08530	COG2304	oxidoreductase activity
EYZ66_08545	COG0714	Associated with various cellular activities
EYZ66_08575	COG0778	Nitroreductase
EYZ66_08585	COG1024	Enoyl-CoA hydratase
EYZ66_08590	COG0625	glutathione transferase activity
EYZ66_08610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYZ66_08645	COG4372	Transposase
EYZ66_08700	COG0701	Predicted permease
EYZ66_08750	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EYZ66_08800	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EYZ66_08800	COG0519	Catalyzes the synthesis of GMP from XMP
EYZ66_08810	COG1570	exodeoxyribonuclease VII activity
EYZ66_08815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EYZ66_08830	COG2202	Pas domain
EYZ66_08830	COG2205	protein histidine kinase activity
EYZ66_08840	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EYZ66_08855	COG0405	Gamma-glutamyltransferase
EYZ66_08875	COG0436	Aminotransferase
EYZ66_08880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EYZ66_08890	COG0335	large ribosomal subunit rRNA binding
EYZ66_08895	COG0336	Belongs to the RNA methyltransferase TrmD family
EYZ66_08900	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EYZ66_08905	COG0228	four-way junction DNA binding
EYZ66_08910	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EYZ66_08920	COG4536	flavin adenine dinucleotide binding
EYZ66_08930	COG3323	Protein of unknown function (DUF1653)
EYZ66_08930	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EYZ66_08940	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EYZ66_08995	COG1024	Enoyl-CoA hydratase
EYZ66_09045	COG0714	Associated with various cellular activities
EYZ66_09050	COG3119	arylsulfatase activity
EYZ66_09055	COG0625	glutathione transferase activity
EYZ66_09060	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EYZ66_09075	COG0800	Aldolase
EYZ66_09095	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EYZ66_09100	COG1737	Transcriptional regulator
EYZ66_09110	COG0572	uridine kinase
EYZ66_09115	COG1024	Enoyl-CoA hydratase
EYZ66_09120	COG0183	Belongs to the thiolase family
EYZ66_09145	COG1984	allophanate hydrolase subunit 2
EYZ66_09150	COG4774	siderophore transport
EYZ66_09155	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EYZ66_09165	COG0745	RESPONSE REGULATOR receiver
EYZ66_09200	COG1166	arginine decarboxylase activity
EYZ66_09220	COG2166	iron-sulfur cluster assembly
EYZ66_09230	COG0316	Belongs to the HesB IscA family
EYZ66_09240	COG0719	Fe-S assembly protein
EYZ66_09245	COG0396	ATPase activity
EYZ66_09250	COG0719	Fe-S assembly protein
EYZ66_09275	COG0561	phosphatase activity
EYZ66_09300	COG0450	alkyl hydroperoxide reductase
EYZ66_09305	COG3634	alkyl hydroperoxide reductase activity
EYZ66_09310	COG0318	PFAM AMP-dependent synthetase and ligase
EYZ66_09315	COG0235	Class ii aldolase
EYZ66_09325	COG1872	DUF167
EYZ66_09335	COG1522	sequence-specific DNA binding
EYZ66_09350	COG2207	Transcriptional regulator
EYZ66_09365	COG0745	RESPONSE REGULATOR receiver
EYZ66_09365	COG2205	protein histidine kinase activity
EYZ66_09365	COG4191	Histidine kinase
EYZ66_09405	COG5001	Diguanylate cyclase
EYZ66_09405	COG3300	MHYT domain
EYZ66_09415	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EYZ66_09420	COG0527	aspartate kinase activity
EYZ66_09425	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EYZ66_09430	COG0537	adenosine 5'-monophosphoramidase activity
EYZ66_09435	COG2835	tetraacyldisaccharide 4'-kinase activity
EYZ66_09450	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EYZ66_09450	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EYZ66_09455	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EYZ66_09460	COG0248	Ppx GppA phosphatase
EYZ66_09465	COG1609	Transcriptional regulator
EYZ66_09485	COG1501	Belongs to the glycosyl hydrolase 31 family
EYZ66_09490	COG1082	Xylose isomerase domain protein TIM barrel
EYZ66_09495	COG0366	Alpha amylase catalytic
EYZ66_09515	COG1640	4-alpha-glucanotransferase
EYZ66_09550	COG2801	Transposase and inactivated derivatives
EYZ66_09555	COG2963	transposase activity
EYZ66_09565	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EYZ66_09575	COG1228	amidohydrolase
EYZ66_09580	COG0415	Belongs to the DNA photolyase family
EYZ66_09585	COG0322	excinuclease ABC activity
EYZ66_09595	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EYZ66_09600	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EYZ66_09620	COG2853	Lipoprotein
EYZ66_09625	COG1643	Atp-dependent helicase
EYZ66_09630	COG2030	dehydratase
EYZ66_09640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYZ66_09640	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EYZ66_09675	COG0471	metal ion transport
EYZ66_09675	COG3273	potassium ion transport
EYZ66_09690	COG2137	regulation of response to DNA damage stimulus
EYZ66_09695	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EYZ66_09700	COG1132	(ABC) transporter
EYZ66_09725	COG0277	FAD linked oxidase domain protein
EYZ66_09735	COG0737	Belongs to the 5'-nucleotidase family
EYZ66_09770	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EYZ66_09775	COG0640	Transcriptional regulator
EYZ66_09795	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EYZ66_09800	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EYZ66_09815	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EYZ66_09820	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EYZ66_09825	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EYZ66_09830	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EYZ66_09835	COG0148	phosphopyruvate hydratase activity
EYZ66_09840	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EYZ66_09845	COG0504	CTP synthase activity
EYZ66_09850	COG0037	tRNA processing
EYZ66_09855	COG0825	malonyl-CoA metabolic process
EYZ66_09860	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EYZ66_09865	COG0511	ligase activity, forming carbon-carbon bonds
EYZ66_09865	COG5016	pyruvate
EYZ66_09875	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EYZ66_09880	COG3104	oligopeptide transport
EYZ66_09890	COG0302	gtp cyclohydrolase
EYZ66_09925	COG0183	Belongs to the thiolase family
EYZ66_09935	COG2272	Belongs to the type-B carboxylesterase lipase family
EYZ66_09940	COG2610	gluconate transmembrane transporter activity
EYZ66_10005	COG3977	Valine--pyruvate aminotransferase
EYZ66_10040	COG0300	oxidoreductase activity
EYZ66_10055	COG1487	ribonuclease activity
EYZ66_10080	COG0776	regulation of translation
EYZ66_10090	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EYZ66_10095	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EYZ66_10100	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EYZ66_10105	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EYZ66_10110	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EYZ66_10145	COG0450	alkyl hydroperoxide reductase
EYZ66_10160	COG1064	alcohol dehydrogenase
EYZ66_10165	COG4771	TonB-dependent receptor
EYZ66_10190	COG0492	ferredoxin-NADP+ reductase activity
EYZ66_10230	COG0385	Bile acid
EYZ66_10235	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_10285	COG1555	photosystem II stabilization
EYZ66_10290	COG0284	orotidine-5'-phosphate decarboxylase activity
EYZ66_10295	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EYZ66_10305	COG0776	regulation of translation
EYZ66_10315	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EYZ66_10330	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EYZ66_10340	COG0402	S-adenosylhomocysteine deaminase activity
EYZ66_10345	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EYZ66_10355	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_10360	COG1187	pseudouridine synthase activity
EYZ66_10365	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EYZ66_10375	COG0009	L-threonylcarbamoyladenylate synthase
EYZ66_10380	COG0613	PHP domain protein
EYZ66_10385	COG2917	probably involved in intracellular septation
EYZ66_10390	COG2350	Protein conserved in bacteria
EYZ66_10405	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EYZ66_10420	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EYZ66_10430	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EYZ66_10450	COG0501	Belongs to the peptidase M48B family
EYZ66_10455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYZ66_10470	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYZ66_10475	COG1115	amino acid carrier protein
EYZ66_10480	COG0733	neurotransmitter:sodium symporter activity
EYZ66_10485	COG0006	proline dipeptidase activity
EYZ66_10485	COG0006	proline dipeptidase activity
EYZ66_10515	COG2165	general secretion pathway protein
EYZ66_10530	COG1459	type II secretion system
EYZ66_10550	COG0288	reversible hydration of carbon dioxide
EYZ66_10555	COG4774	siderophore transport
EYZ66_10580	COG0515	serine threonine protein kinase
EYZ66_10580	COG2815	serine threonine protein kinase
EYZ66_10595	COG3023	N-Acetylmuramoyl-L-alanine amidase
EYZ66_10605	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EYZ66_10610	COG1960	acyl-CoA dehydrogenase activity
EYZ66_10625	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EYZ66_10630	COG4969	Belongs to the N-Me-Phe pilin family
EYZ66_10645	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EYZ66_10650	COG0237	dephospho-CoA kinase activity
EYZ66_10660	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EYZ66_10665	COG0653	protein targeting
EYZ66_10675	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EYZ66_10690	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EYZ66_10695	COG1181	Belongs to the D-alanine--D-alanine ligase family
EYZ66_10700	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EYZ66_10705	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EYZ66_10710	COG0772	Belongs to the SEDS family
EYZ66_10720	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYZ66_10725	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EYZ66_10730	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EYZ66_10745	COG0275	rRNA processing
EYZ66_10750	COG2001	Belongs to the MraZ family
EYZ66_10770	COG0792	nuclease activity
EYZ66_10775	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EYZ66_10785	COG2969	positive regulation of protein catabolic process
EYZ66_10790	COG0625	glutathione transferase activity
EYZ66_10795	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EYZ66_10800	COG0723	plastoquinol--plastocyanin reductase activity
EYZ66_10805	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EYZ66_10810	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EYZ66_10815	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EYZ66_10830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYZ66_10840	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EYZ66_10845	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EYZ66_10850	COG5007	Belongs to the BolA IbaG family
EYZ66_10870	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EYZ66_10885	COG1137	ATPase activity
EYZ66_10905	COG1660	Displays ATPase and GTPase activities
EYZ66_10915	COG2239	Acts as a magnesium transporter
EYZ66_10930	COG0424	maF-like protein
EYZ66_10940	COG1792	Involved in formation and maintenance of cell shape
EYZ66_10945	COG1077	Cell shape determining protein MreB Mrl
EYZ66_10955	COG0154	amidase activity
EYZ66_10960	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EYZ66_10965	COG2840	Smr protein MutS2
EYZ66_10975	COG0513	Belongs to the DEAD box helicase family
EYZ66_10980	COG2890	protein-(glutamine-N5) methyltransferase activity
EYZ66_10985	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EYZ66_10990	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EYZ66_11005	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EYZ66_11015	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EYZ66_11020	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EYZ66_11025	COG0193	aminoacyl-tRNA hydrolase activity
EYZ66_11055	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EYZ66_11065	COG0142	geranyltranstransferase activity
EYZ66_11100	COG1346	cytolysis
EYZ66_11120	COG1612	heme a metabolic process
EYZ66_11125	COG0488	(ABC) transporter
EYZ66_11130	COG1448	Aminotransferase
EYZ66_11140	COG0500	methyltransferase
EYZ66_11145	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EYZ66_11150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYZ66_11160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EYZ66_11165	COG1702	phosphate starvation-inducible protein PhoH
EYZ66_11170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EYZ66_11175	COG4535	Mg2 and Co2 transporter CorC
EYZ66_11180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EYZ66_11185	COG0495	leucyl-tRNA aminoacylation
EYZ66_11240	COG0587	DNA-directed DNA polymerase activity
EYZ66_11270	COG0318	PFAM AMP-dependent synthetase and ligase
EYZ66_11290	COG1960	acyl-CoA dehydrogenase activity
EYZ66_11305	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EYZ66_11320	COG0488	(ABC) transporter
EYZ66_11330	COG0189	ligase activity
EYZ66_11340	COG3077	Addiction module antitoxin, RelB DinJ family
EYZ66_11350	COG0189	ligase activity
EYZ66_11350	COG4067	protein conserved in archaea
EYZ66_11355	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EYZ66_11360	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EYZ66_11365	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EYZ66_11385	COG2271	Major facilitator Superfamily
EYZ66_11440	COG1091	dTDP-4-dehydrorhamnose reductase activity
EYZ66_11455	COG1088	dTDP-glucose 4,6-dehydratase activity
EYZ66_11490	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EYZ66_11495	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_11525	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EYZ66_11545	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EYZ66_11550	COG0367	asparagine synthase
EYZ66_11570	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EYZ66_11595	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EYZ66_11645	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYZ66_11665	COG3621	Patatin-like phospholipase
EYZ66_11670	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EYZ66_11715	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EYZ66_11715	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EYZ66_11725	COG4772	TonB-dependent receptor
EYZ66_11755	COG2211	Major facilitator Superfamily
EYZ66_11775	COG3119	arylsulfatase activity
EYZ66_11795	COG0596	Alpha beta hydrolase
EYZ66_11835	COG0475	glutathione-regulated potassium exporter activity
EYZ66_11840	COG0545	Peptidyl-prolyl cis-trans isomerase
EYZ66_11850	COG0488	(ABC) transporter
EYZ66_11855	COG2827	Endonuclease containing a URI domain
EYZ66_11860	COG3118	belongs to the thioredoxin family
EYZ66_11880	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EYZ66_11905	COG0165	Argininosuccinate lyase
EYZ66_11920	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EYZ66_11945	COG0004	ammonium transporteR
EYZ66_11950	COG0347	Belongs to the P(II) protein family
EYZ66_11970	COG0210	DNA helicase
EYZ66_11990	COG4771	TonB-dependent receptor
EYZ66_12000	COG5001	Diguanylate cyclase
EYZ66_12005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYZ66_12015	COG0789	Transcriptional regulator
EYZ66_12020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EYZ66_12035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYZ66_12040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYZ66_12055	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EYZ66_12060	COG0330	HflC and HflK could
EYZ66_12065	COG0330	HflC and HflK could
EYZ66_12070	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EYZ66_12075	COG1923	regulation of RNA biosynthetic process
EYZ66_12085	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EYZ66_12090	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYZ66_12095	COG0802	atpase or kinase
EYZ66_12100	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EYZ66_12100	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EYZ66_12110	COG0175	sulfate reduction
EYZ66_12115	COG1956	GAF domain-containing protein
EYZ66_12120	COG0017	Asparaginyl-tRNA synthetase
EYZ66_12165	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_12195	COG0596	Alpha beta hydrolase
EYZ66_12200	COG4145	pantothenate transmembrane transporter activity
EYZ66_12220	COG1278	Cold shock
EYZ66_12235	COG0848	biopolymer transport protein
EYZ66_12240	COG0848	biopolymer transport protein
EYZ66_12245	COG0811	peptide transport
EYZ66_12250	COG0811	peptide transport
EYZ66_12265	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EYZ66_12270	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EYZ66_12280	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
EYZ66_12285	COG1051	belongs to the nudix hydrolase family
EYZ66_12295	COG0509	glycine decarboxylation via glycine cleavage system
EYZ66_12300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYZ66_12305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYZ66_12310	COG0006	proline dipeptidase activity
EYZ66_12315	COG3079	Belongs to the UPF0149 family
EYZ66_12335	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EYZ66_12340	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EYZ66_12345	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EYZ66_12350	COG2095	MarC family integral membrane protein
EYZ66_12355	COG1490	D-aminoacyl-tRNA deacylase activity
EYZ66_12360	COG1217	gtp-binding protein TYPA
EYZ66_12365	COG0174	glutamine synthetase
EYZ66_12375	COG3852	Histidine kinase
EYZ66_12380	COG2204	response regulator
EYZ66_12385	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EYZ66_12390	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EYZ66_12405	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EYZ66_12410	COG4942	peptidase
EYZ66_12415	COG0793	Belongs to the peptidase S41A family
EYZ66_12420	COG0107	imidazoleglycerol-phosphate synthase activity
EYZ66_12425	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EYZ66_12430	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EYZ66_12435	COG0131	Imidazoleglycerol-phosphate dehydratase
EYZ66_12445	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EYZ66_12510	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EYZ66_12520	COG1360	Flagellar Motor Protein
EYZ66_12550	COG0038	chloride channel
EYZ66_12560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EYZ66_12595	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EYZ66_12615	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EYZ66_12620	COG1558	bacterial-type flagellum-dependent cell motility
EYZ66_12670	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EYZ66_12710	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EYZ66_12720	COG1987	bacterial-type flagellum assembly
EYZ66_12740	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EYZ66_12770	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EYZ66_12780	COG1677	Flagellar hook-basal body complex protein FliE
EYZ66_12785	COG2204	response regulator
EYZ66_12800	COG1392	Phosphate transport regulator
EYZ66_12810	COG0746	molybdenum cofactor guanylyltransferase activity
EYZ66_12815	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EYZ66_12815	COG3608	succinylglutamate desuccinylase aspartoacylase
EYZ66_12835	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_12840	COG2308	Evidence 4 Homologs of previously reported genes of
EYZ66_12890	COG1053	succinate dehydrogenase
EYZ66_12900	COG1960	acyl-CoA dehydrogenase activity
EYZ66_12905	COG1960	acyl-CoA dehydrogenase activity
EYZ66_12910	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_12915	COG0183	Belongs to the thiolase family
EYZ66_12920	COG1960	acyl-CoA dehydrogenase activity
EYZ66_12925	COG1960	acyl-CoA dehydrogenase activity
EYZ66_12930	COG1024	Enoyl-CoA hydratase
EYZ66_12950	COG0346	lactoylglutathione lyase activity
EYZ66_12960	COG2267	carboxylic ester hydrolase activity
EYZ66_12990	COG4638	Rieske (2fe-2S)
EYZ66_12995	COG1024	Enoyl-CoA hydratase
EYZ66_13000	COG2070	2-Nitropropane dioxygenase
EYZ66_13015	COG1960	acyl-CoA dehydrogenase activity
EYZ66_13020	COG1960	acyl-CoA dehydrogenase activity
EYZ66_13030	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_13045	COG1309	transcriptional regulator
EYZ66_13065	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_13070	COG1028	Short-chain dehydrogenase reductase Sdr
EYZ66_13085	COG1902	pentaerythritol trinitrate reductase activity
EYZ66_13095	COG1053	succinate dehydrogenase
EYZ66_13105	COG2963	transposase activity
EYZ66_13110	COG2801	Transposase and inactivated derivatives
EYZ66_13125	COG1024	Enoyl-CoA hydratase
EYZ66_13130	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EYZ66_13140	COG1309	transcriptional regulator
EYZ66_13150	COG1960	acyl-CoA dehydrogenase activity
EYZ66_13155	COG1040	competence protein
EYZ66_13175	COG0110	maltose O-acetyltransferase activity
EYZ66_13185	COG1045	serine acetyltransferase
EYZ66_13190	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EYZ66_13195	COG0493	'glutamate synthase
EYZ66_13200	COG0067	glutamate synthase
EYZ66_13200	COG0069	glutamate synthase activity
EYZ66_13200	COG0070	glutamate synthase
EYZ66_13205	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EYZ66_13210	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EYZ66_13245	COG0254	rRNA binding
EYZ66_13250	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EYZ66_13255	COG0018	arginyl-trna synthetase
EYZ66_13265	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EYZ66_13270	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EYZ66_13280	COG2226	methyltransferase
EYZ66_13290	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EYZ66_13295	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EYZ66_13300	COG0140	phosphoribosyl-ATP diphosphatase activity
EYZ66_13310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EYZ66_13320	COG1132	(ABC) transporter
EYZ66_13340	COG3806	Anti-sigma factor
EYZ66_13345	COG1595	DNA-templated transcription, initiation
EYZ66_13360	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EYZ66_13370	COG1757	Na H antiporter
EYZ66_13375	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EYZ66_13380	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EYZ66_13385	COG1509	lysine 2,3-aminomutase activity
EYZ66_13395	COG3830	Belongs to the UPF0237 family
EYZ66_13395	COG0560	Phosphoserine phosphatase
EYZ66_13415	COG2153	protein acetylation
EYZ66_13425	COG0126	phosphoglycerate kinase activity
EYZ66_13435	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EYZ66_13445	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EYZ66_13450	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EYZ66_13455	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EYZ66_13460	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EYZ66_13465	COG0189	ligase activity
EYZ66_13475	COG1678	Uncharacterized ACR, COG1678
EYZ66_13480	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EYZ66_13505	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EYZ66_13510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EYZ66_13510	COG2813	Specifically methylates the guanine in position
EYZ66_13520	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EYZ66_13525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EYZ66_13535	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EYZ66_13540	COG2363	Small membrane protein
EYZ66_13550	COG2177	Part of the ABC transporter FtsEX involved in
EYZ66_13555	COG2884	Cell division ATP-binding protein ftsE
EYZ66_13560	COG0552	protein localization to endoplasmic reticulum
EYZ66_13565	COG0742	ribosomal rna small subunit methyltransferase
EYZ66_13575	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EYZ66_13580	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EYZ66_13585	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EYZ66_13590	COG2003	Belongs to the UPF0758 family
EYZ66_13595	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EYZ66_13605	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EYZ66_13610	COG1309	transcriptional regulator
EYZ66_13630	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EYZ66_13635	COG1561	YicC-like family, N-terminal region
EYZ66_13650	COG2801	Transposase and inactivated derivatives
EYZ66_13665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYZ66_13670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYZ66_13675	COG3038	cytochrome b561
EYZ66_13680	COG1309	transcriptional regulator
EYZ66_13765	COG3246	L-lysine catabolic process to acetate
EYZ66_13770	COG2175	clavaminate synthase activity
EYZ66_13785	COG2715	membrane protein required for spore maturation
EYZ66_13800	COG0189	ligase activity
EYZ66_13810	COG0726	polysaccharide deacetylase
EYZ66_13820	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EYZ66_13845	COG1116	anion transmembrane transporter activity
EYZ66_13860	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EYZ66_13865	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EYZ66_13870	COG2855	membrane
EYZ66_13875	COG1115	amino acid carrier protein
EYZ66_13880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYZ66_13890	COG0372	Belongs to the citrate synthase family
EYZ66_13895	COG0280	phosphate acetyltransferase
EYZ66_13920	COG3279	Response regulator of the LytR AlgR family
EYZ66_13925	COG2972	Histidine kinase
EYZ66_13935	COG0297	glycogen (starch) synthase activity
EYZ66_13940	COG0033	Phosphoglucomutase
EYZ66_13950	COG0058	SHG alpha-glucan phosphorylase activity
EYZ66_13960	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EYZ66_13965	COG1640	4-alpha-glucanotransferase
EYZ66_13975	COG0194	GDP metabolic process
EYZ66_13980	COG1758	RNA polymerase activity
EYZ66_13985	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EYZ66_14000	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EYZ66_14005	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EYZ66_14010	COG3161	chorismate lyase activity
EYZ66_14040	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EYZ66_14045	COG1607	acyl-coa hydrolase
EYZ66_14050	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EYZ66_14055	COG0210	DNA helicase
EYZ66_14065	COG1253	flavin adenine dinucleotide binding
EYZ66_14075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYZ66_14090	COG0457	Tetratricopeptide repeat
EYZ66_14100	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EYZ66_14105	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EYZ66_14110	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EYZ66_14115	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EYZ66_14120	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EYZ66_14125	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EYZ66_14135	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EYZ66_14145	COG0356	it plays a direct role in the translocation of protons across the membrane
EYZ66_14155	COG1475	DNA binding
EYZ66_14160	COG1192	Involved in chromosome partitioning
EYZ66_14165	COG0357	Ribosomal RNA small subunit methyltransferase G
EYZ66_14175	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EYZ66_14180	COG0706	membrane insertase activity
EYZ66_14185	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EYZ66_14190	COG0594	ribonuclease P activity
EYZ66_14195	COG0230	Belongs to the bacterial ribosomal protein bL34 family