locus-tag	class	description
EI546_00010	ENOG41083X6	30S ribosomal protein S21
EI546_00015	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EI546_00020	ENOG4105MS2	ribosomal subunit Interface protein
EI546_00045	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
EI546_00055	ENOG4105PM1	preprotein translocase subunit SecE
EI546_00065	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
EI546_00070	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
EI546_00075	ENOG4107VNI	ribosomal protein l10
EI546_00080	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
EI546_00085	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EI546_00090	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EI546_00110	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
EI546_00140	ENOG4105CI3	gtp-binding protein typa
EI546_00145	ENOG4108V0P	LemA family
EI546_00155	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
EI546_00160	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EI546_00170	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
EI546_00175	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
EI546_00180	ENOG4105EA8	2-Nitropropane dioxygenase
EI546_00190	ENOG4105VEQ	Cold shock protein
EI546_00195	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
EI546_00205	ENOG4105EXU	Membrane
EI546_00215	ENOG4105FE9	pseudouridine synthase
EI546_00230	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
EI546_00240	ENOG4108UB4	uncharacterized protein ygjQ
EI546_00255	ENOG4105CJ1	ABC, transporter
EI546_00260	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
EI546_00275	ENOG4108Z7R	Chaperone CsaA
EI546_00305	ENOG4105BZ1	(ABC) transporter
EI546_00310	ENOG4107RDP	Dehydrogenase
EI546_00315	ENOG4107R6T	Involved in the transcription termination process (By similarity)
EI546_00325	ENOG4105VIE	preprotein translocase, subunit YajC
EI546_00330	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
EI546_00345	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
EI546_00350	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
EI546_00370	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
EI546_00380	ENOG4105EGD	dinuclear metal center protein, YbgI family
EI546_00385	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
EI546_00395	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
EI546_00400	ENOG4105DU6	RNA polymerase
EI546_00405	ENOG4107S6X	Glycosyl transferase, family 2
EI546_00420	ENOG4107R0I	Cell wall formation (By similarity)
EI546_00425	ENOG4105CHM	Aminotransferase
EI546_00430	ENOG4105C0H	protease
EI546_00440	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
EI546_00450	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
EI546_00455	ENOG4105KNE	Phosphatidate cytidylyltransferase
EI546_00465	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EI546_00470	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
EI546_00475	ENOG4108EKN	Biotin protein ligase C terminal domain
EI546_00485	ENOG4107RIV	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
EI546_00500	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
EI546_00515	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
EI546_00520	ENOG4105BZ1	(ABC) transporter
EI546_00525	ENOG4105C8B	TIGR00159 family
EI546_00530	ENOG4105EEI	dihydropteroate synthase
EI546_00545	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EI546_00550	ENOG4105CP7	Triose-phosphate isomerase
EI546_00555	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
EI546_00570	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
EI546_00580	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
EI546_00590	ENOG4105C1J	atp-dependent rna helicase
EI546_00595	ENOG4107RT3	EamA-like transporter family
EI546_00600	ENOG4105DQ4	alcohol dehydrogenase
EI546_00610	ENOG4105D7N	magnesium and cobalt transport protein CorA
EI546_00615	ENOG4105DQE	DNA ligase
EI546_00625	ENOG4105DQE	DNA ligase
EI546_00730	ENOG41067XF	inhibitor
EI546_00790	ENOG4105QNR	S1 RNA binding domain protein
EI546_00835	ENOG4105EFZ	amidohydrolase
EI546_00860	ENOG4105C9Q	fumarate hydratase class II
EI546_00880	ENOG4105CD8	aminopeptidase N
EI546_00895	ENOG4105CBC	glutamate synthase
EI546_00925	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
EI546_00930	ENOG4105C4R	Atp-dependent dna helicase
EI546_00935	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
EI546_00970	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
EI546_00975	ENOG4107W2A	UPF0173 metal-dependent hydrolase
EI546_00980	ENOG4105DTQ	mandelate racemase muconate lactonizing
EI546_01015	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
EI546_01030	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
EI546_01035	ENOG4105EYW	Ion transport protein
EI546_01045	ENOG4105DFA	alanine racemase domain protein
EI546_01055	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
EI546_01060	ENOG4105D9R	oxidoreductase
EI546_01065	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
EI546_01075	ENOG4108URH	decarboxylase
EI546_01080	ENOG4105DSF	transport protein
EI546_01125	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
EI546_01145	ENOG4108JQ1	Dehydrogenase
EI546_01150	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
EI546_01175	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
EI546_01220	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
EI546_01225	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
EI546_01230	ENOG4107U9T	Pfam:Ribonuclease_BN
EI546_01240	ENOG4105C25	Primosomal protein n'
EI546_01245	ENOG41080B9	Binds together with S18 to 16S ribosomal RNA (By similarity)
EI546_01250	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
EI546_01255	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
EI546_01270	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
EI546_01275	ENOG4105CUT	histidyl-tRNA synthetase
EI546_01280	ENOG4105CNT	hydrolase family 2
EI546_01290	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
EI546_01315	ENOG4105DY9	regulatoR
EI546_01335	ENOG4108RCM	Nitroreductase
EI546_01345	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
EI546_01355	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
EI546_01390	ENOG4105CNU	cell division protein FtsK
EI546_01400	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
EI546_01415	ENOG4105D3R	alkyl hydroperoxide reductase
EI546_01420	ENOG4105DFD	Na H antiporter
EI546_01425	ENOG4105C1Q	protoporphyrinogen oxidase
EI546_01445	ENOG4105C28	cystathionine
EI546_01540	ENOG4105KA0	thioesterase Superfamily protein
EI546_01545	ENOG4105E4F	Isochorismate synthase
EI546_01550	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
EI546_01560	ENOG4105CJ1	ABC, transporter
EI546_01575	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EI546_01595	ENOG4105CBC	glutamate synthase
EI546_01625	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
EI546_01650	ENOG4108U51	Universal stress protein
EI546_01655	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
EI546_01660	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
EI546_01665	ENOG4105K63	Thioredoxin
EI546_01680	ENOG4105BZU	Histidine kinase
EI546_01685	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
EI546_01780	ENOG4105CIG	ABC transporter
EI546_01790	ENOG4105DZ0	fad dependent oxidoreductase
EI546_01815	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
EI546_01820	ENOG4105C1J	atp-dependent rna helicase
EI546_01835	ENOG4105C27	TonB-dependent Receptor Plug
EI546_01845	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
EI546_01860	ENOG4107VAM	peptidase, m28
EI546_01865	ENOG4108F3G	Type I restriction-modification system, R subunit
EI546_01885	ENOG4107QTH	restriction modification system DNA specificity domain
EI546_01920	ENOG4105C1G	acyl-Coa dehydrogenase
EI546_01985	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
EI546_01995	ENOG4108VVK	transcriptional Regulator, AsnC
EI546_02015	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
EI546_02020	ENOG4105CAT	Cytidine monophosphate kinase
EI546_02030	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
EI546_02035	ENOG4105GFR	rna polymerase sigma factor
EI546_02055	ENOG4105DEU	major facilitator superfamily
EI546_02070	ENOG4105E0X	reductase
EI546_02075	ENOG4105E0X	reductase
EI546_02080	ENOG4107QN2	dihydrolipoyl dehydrogenase
EI546_02085	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
EI546_02115	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EI546_02125	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
EI546_02155	ENOG4107QI6	Cysteine desulfurase
EI546_02175	ENOG4105CK7	Sodium proline symporter
EI546_02190	ENOG41090HT	Inherit from COG: transposase
EI546_02225	ENOG4105CHR	reductase
EI546_02230	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
EI546_02240	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EI546_02245	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
EI546_02250	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EI546_02255	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EI546_02260	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EI546_02265	ENOG4105DCI	Phosphohydrolase
EI546_02270	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EI546_02275	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
EI546_02280	ENOG41088SP	formiminoglutamate hydrolase
EI546_02285	ENOG4105CI2	imidazolone-5-propionate hydrolase
EI546_02290	ENOG4107YZX	Universal stress protein
EI546_02295	ENOG4105C28	cystathionine
EI546_02300	ENOG4105FJR	Lmbe family
EI546_02325	ENOG4107TPS	domain protein
EI546_02335	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
EI546_02340	ENOG4105C2F	Histidine kinase
EI546_02345	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
EI546_02370	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
EI546_02380	ENOG4105C5H	ABC transporter
EI546_02400	ENOG4107QX3	carboxylase
EI546_02405	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
EI546_02410	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
EI546_02435	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
EI546_02445	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
EI546_02450	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
EI546_02470	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
EI546_02475	ENOG4105CQB	FAD linked oxidase domain protein
EI546_02485	ENOG4105CPK	Glycosyl transferase (Group 1
EI546_02495	ENOG4105D17	glycoside hydrolase, family 3 domain protein
EI546_02505	ENOG4105DF6	Fe-S oxidoreductase
EI546_02515	ENOG4105DF6	Fe-S oxidoreductase
EI546_02520	ENOG4107PE3	Mammalian cell entry related domain protein
EI546_02525	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
EI546_02545	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
EI546_02550	ENOG4108MJ3	acetyltransferase
EI546_02555	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
EI546_02560	ENOG4108TZV	Membrane
EI546_02565	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
EI546_02575	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
EI546_02580	ENOG4105KJF	protein tyrosine phosphatase
EI546_02590	ENOG4105QD8	tetrapyrrole corrin porphyrin
EI546_02600	ENOG4105HHA	aminodeoxychorismate lyase
EI546_02610	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
EI546_02615	ENOG4105C0H	protease
EI546_02630	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
EI546_02635	ENOG41090R7	Ferric uptake
EI546_02640	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
EI546_02650	ENOG4105C8Y	Acetylornithine aminotransferase
EI546_02670	ENOG4105E2X	shikimate dehydrogenase
EI546_02680	ENOG4105DXN	mazG family
EI546_02685	ENOG4105E1F	short-chain dehydrogenase reductase
EI546_02690	ENOG4108VX5	3-methyladenine DNA glycosylase
EI546_02735	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EI546_02745	ENOG4105ER2	Ompa motb domain protein
EI546_02755	ENOG4105CHR	reductase
EI546_02775	ENOG4105CFG	Acts as a chaperone (By similarity)
EI546_02785	ENOG4105C0B	DNA polymerase III (alpha subunit)
EI546_02790	ENOG4105CD5	CoA-binding domain protein
EI546_02810	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
EI546_02820	ENOG4107QKA	exodeoxyribonuclease V beta
EI546_02825	ENOG4105DSY	exodeoxyribonuclease V, gamma
EI546_02830	ENOG4107QYX	exodeoxyribonuclease v alpha
EI546_02840	ENOG4105FQP	Beta-lactamase
EI546_02860	ENOG4105FAE	von Willebrand factor, type A
EI546_02865	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
EI546_02875	ENOG4108VKQ	nitriC oxide reductase
EI546_02905	ENOG4105C34	Pseudouridine synthase
EI546_02910	ENOG4107ZXU	DSBA oxidoreductase
EI546_02945	ENOG4108JPW	Aminotransferase
EI546_02975	ENOG41061HS	cysteine-type endopeptidase activity
EI546_02990	ENOG4105C5H	ABC transporter
EI546_03000	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
EI546_03010	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
EI546_03015	ENOG4107ZNS	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
EI546_03020	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
EI546_03035	ENOG4108SHN	Glycosyl transferase, family 2
EI546_03040	ENOG4106WTF	Glycosyl transferase, family 2
EI546_03050	ENOG4106WTF	Glycosyl transferase, family 2
EI546_03065	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
EI546_03075	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EI546_03080	ENOG4107SF2	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
EI546_03100	ENOG4105C3F	Signal peptidase i
EI546_03105	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
EI546_03115	ENOG4105FA0	parb-like partition protein
EI546_03120	ENOG4107QJE	Chromosome Partitioning Protein
EI546_03125	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
EI546_03150	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
EI546_03160	ENOG41082BM	Transcriptional regulator, arsr family
EI546_03170	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
EI546_03175	ENOG4105E9K	Isocitrate dehydrogenase
EI546_03190	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
EI546_03200	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
EI546_03220	ENOG4105C9U	ATP-dependent DNA helicase RecQ
EI546_03225	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
EI546_03250	ENOG4105C3M	thioredoxin reductase
EI546_03255	ENOG4105DWT	malate dehydrogenase (quinone)
EI546_03285	ENOG4105DZR	Type I site-specific deoxyribonuclease
EI546_03335	ENOG4105DB4	
EI546_03545	ENOG4105E0M	Sulfatase
EI546_03555	ENOG4105GR3	Histidine kinase
EI546_03560	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
EI546_03570	ENOG4105CS2	ec 3.2.1.21
EI546_03620	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
EI546_03755	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
EI546_03790	ENOG4107MII	Sugar-specific transcriptional regulator TrmB
EI546_03815	ENOG4105DQE	DNA ligase
EI546_03820	ENOG4105ID8	Transcriptional regulator, ARAC family
EI546_03845	ENOG4105D5D	udp-galactopyranose mutase
EI546_03940	ENOG4107XVH	Transcriptional regulator
EI546_03945	ENOG4105K8N	protein family UPF0079, ATPase
EI546_03965	ENOG4105D49	3-dehydroquinate synthase
EI546_03975	ENOG4105DU1	integral membrane protein, terc
EI546_03995	ENOG4105UYK	outer membrane protein a
EI546_04010	ENOG4105CPP	Dehydrogenase, E1 component
EI546_04025	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
EI546_04035	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
EI546_04040	ENOG4105C98	muts2 protein
EI546_04045	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
EI546_04055	ENOG4105EUJ	GTP cyclohydrolase i
EI546_04060	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
EI546_04070	ENOG4105BZU	Histidine kinase
EI546_04080	ENOG4105CD3	dihydroorotase
EI546_04100	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
EI546_04105	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
EI546_04110	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EI546_04115	ENOG4105CSM	endonuclease III
EI546_04125	ENOG4105CSR	polyphosphate kinase 2
EI546_04130	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EI546_04140	ENOG4105RHA	ABC transporter, permease
EI546_04145	ENOG4108IUX	(ABC) transporter
EI546_04150	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EI546_04155	ENOG4107XPB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EI546_04165	ENOG4105ECP	epimerase
EI546_04170	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
EI546_04180	ENOG4105CM2	brancheD-chain amino acid aminotransferase
EI546_04195	ENOG4107RRZ	synthase
EI546_04210	ENOG41083GQ	Protein CrcB homolog
EI546_04240	ENOG4105D5P	Methylmalonyl-coA mutase
EI546_04260	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
EI546_04265	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
EI546_04290	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
EI546_04320	ENOG4105VEQ	Cold shock protein
EI546_04330	ENOG4108RWI	nicotinamidase
EI546_04335	ENOG4105DAP	Nicotinate phosphoribosyltransferase
EI546_04375	ENOG4105K89	arsenate reductase
EI546_04380	ENOG4107RNH	Outer membrane receptor FepA
EI546_04385	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
EI546_04400	ENOG41080WS	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
EI546_04420	ENOG4105EN6	Membrane
EI546_04425	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
EI546_04440	ENOG4105KWI	UPF0339 protein
EI546_04445	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
EI546_04465	ENOG4108YYC	ycei family
EI546_04470	ENOG4105EUB	pirin domain protein
EI546_04485	ENOG4105VCH	membrane
EI546_04490	ENOG4105CUY	Mechanosensitive ion channel
EI546_04505	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
EI546_04510	ENOG4105CSV	Glutaminase
EI546_04520	ENOG4105KZX	Pterin carbinolamine dehydratase
EI546_04525	ENOG4105CDY	transcriptional regulatory protein
EI546_04530	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EI546_04545	ENOG4107RJC	Iron-containing alcohol dehydrogenase
EI546_04550	ENOG4107SID	ATP-dependent exodnase (exonuclease v)
EI546_04565	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
EI546_04575	ENOG4105C6E	dna polymerase iii
EI546_04585	ENOG4107R4J	Chloride channel
EI546_04595	ENOG4105DY9	regulatoR
EI546_04600	ENOG4108IE3	prolyl oligopeptidase
EI546_04620	ENOG4105DC7	peptidase M24
EI546_04635	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
EI546_04650	ENOG4105CHR	reductase
EI546_04670	ENOG4105D7Z	glutathione synthase
EI546_04680	ENOG4108WIQ	phosphoesterase PA-phosphatase related protein
EI546_04685	ENOG4108CSZ	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
EI546_04695	ENOG4105CHH	sulfate transporter
EI546_04725	ENOG4105C5Q	Transcriptional regulator
EI546_04730	ENOG4105DXD	2-methylcitrate dehydratase
EI546_04740	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
EI546_04760	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
EI546_04775	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
EI546_04780	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
EI546_04785	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
EI546_04850	ENOG4105D78	K07001 NTE family protein
EI546_04855	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
EI546_04865	ENOG4105BZU	Histidine kinase
EI546_04875	ENOG4105CGK	Exodeoxyribonuclease III
EI546_04890	ENOG4105F7J	membrane-bound serine protease
EI546_04895	ENOG4107QX8	SPFH domain, Band 7 family protein
EI546_04930	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
EI546_04955	ENOG4105D3R	alkyl hydroperoxide reductase
EI546_04970	ENOG4105DHJ	ABC, transporter
EI546_04975	ENOG4105CY3	ABC transporter, permease
EI546_05025	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EI546_05030	ENOG4108I0Z	Aconitate hydratase
EI546_05035	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
EI546_05040	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
EI546_05050	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
EI546_05075	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
EI546_05100	ENOG4105CGH	5'-nucleotidase
EI546_05105	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
EI546_05115	ENOG410829K	Lysine exporter protein (Lyse ygga)
EI546_05120	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
EI546_05125	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
EI546_05130	ENOG4106BRA	Membrane
EI546_05135	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
EI546_05145	ENOG4105CXT	aspartate transcarbamylase
EI546_05150	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
EI546_05160	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
EI546_05165	ENOG4105DF5	DNA topoisomerase IV, subunit A
EI546_05170	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
EI546_05175	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EI546_05190	ENOG4105C3G	gtp-binding protein
EI546_05200	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
EI546_05210	ENOG4108VXD	carboxy-peptidase
EI546_05215	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
EI546_05220	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EI546_05230	ENOG41083ND	50S ribosomal protein L33
EI546_05235	ENOG4105KDC	50s ribosomal protein l28
EI546_05240	ENOG4105CEV	competence damage-inducible protein
EI546_05245	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
EI546_05250	ENOG4108IRC	dna polymerase iii
EI546_05265	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
EI546_05275	ENOG4107RJ1	sodium solute
EI546_05285	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
EI546_05300	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
EI546_05340	ENOG4105DG6	mannose-6-phosphate isomerase
EI546_05355	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
EI546_05375	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EI546_05420	ENOG4105CN9	Peptidase m42 family protein
EI546_05425	ENOG4105BZG	amino acid carrier protein
EI546_05435	ENOG4107QWK	SAICAR synthetase
EI546_05440	ENOG4105C9A	Phoh family
EI546_05465	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
EI546_05480	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
EI546_05575	ENOG4107S1E	Beta-lactamase
EI546_05610	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
EI546_05650	ENOG4105C58	cytochrome c oxidase accessory protein ccog
EI546_05655	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
EI546_05675	ENOG4105C59	p-type ATPase
EI546_05700	ENOG4105EMU	Dehydrogenase
EI546_05705	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
EI546_05730	ENOG41067HZ	cytochrome C, class I
EI546_05740	ENOG410847I	Transcriptional regulator, BadM Rrf2 family
EI546_05755	ENOG4108RMU	ferritin dps family protein
EI546_05785	ENOG4105CDV	Ompa motb domain protein
EI546_05810	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EI546_05815	ENOG4105MPN	Membrane
EI546_05865	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
EI546_05870	ENOG4105CPF	Cell wall formation (By similarity)
EI546_05875	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
EI546_05880	ENOG4105D3Q	Sugar transferase
EI546_05905	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
EI546_05910	ENOG4105C30	Nad-dependent epimerase dehydratase
EI546_05920	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
EI546_05950	ENOG4105CG5	Glycosyl transferase (Group 1
EI546_05985	ENOG4108IJ1	Dehydrogenase
EI546_06015	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
EI546_06025	ENOG4105C11	sulfate adenylyltransferase), subunit 2
EI546_06030	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
EI546_06040	ENOG4108IAJ	Nad-dependent epimerase dehydratase
EI546_06045	ENOG4107QQG	Dehydrogenase
EI546_06050	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
EI546_06060	ENOG4108IYU	L-aspartate oxidase
EI546_06065	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
EI546_06075	ENOG4105EJQ	L-serine dehydratase
EI546_06080	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
EI546_06110	ENOG4108Z6B	deaminase
EI546_06115	ENOG4107QSA	Oxaloacetate decarboxylase
EI546_06120	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
EI546_06125	ENOG4107QX3	carboxylase
EI546_06130	ENOG41090R7	Ferric uptake
EI546_06155	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
EI546_06170	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
EI546_06175	ENOG4108D32	Methyltransferase
EI546_06200	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
EI546_06205	ENOG4105D3Q	Sugar transferase
EI546_06230	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
EI546_06240	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
EI546_06250	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
EI546_06265	ENOG4105C19	ABC transporter
EI546_06330	ENOG4108KMV	Glycosyl transferase (Group 1
EI546_06335	ENOG4105CPK	Glycosyl transferase (Group 1
EI546_06340	ENOG4105K64	Glycosyl transferase, family 2
EI546_06355	ENOG4107T8Q	Glycosyl transferase (Group 1
EI546_06370	ENOG4105EY8	ABC transporter
EI546_06525	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
EI546_06655	ENOG4107H6E	
EI546_06660	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
EI546_06670	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
EI546_06685	ENOG4108URH	decarboxylase
EI546_06715	ENOG4105CPP	Dehydrogenase, E1 component
EI546_06725	ENOG4107Y2X	deaminase
EI546_06730	ENOG4105DWV	Homoserine O-trans-acetylase
EI546_06740	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
EI546_06755	ENOG4105CDU	Replicative dna helicase
EI546_06760	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
EI546_06775	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
EI546_06780	ENOG4105CV1	Transketolase (EC 2.2.1.1)
EI546_06785	ENOG4108IUS	Transketolase
EI546_06800	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
EI546_06805	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
EI546_06815	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
EI546_06820	ENOG4105C9U	ATP-dependent DNA helicase RecQ
EI546_06825	ENOG4105C2X	Arabinose 5-phosphate isomerase
EI546_06830	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
EI546_06840	ENOG4108IUZ	ABC transporter
EI546_06845	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
EI546_06870	ENOG4107T8Q	Glycosyl transferase (Group 1
EI546_06875	ENOG4107XU6	Glycosyl transferase (Group 1
EI546_06880	ENOG4107SBE	Glycosyl transferase (Group 1
EI546_06885	ENOG4108WBT	adenosyltransferase
EI546_06895	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
EI546_06925	ENOG4107RH8	nuclease SbcCD subunit D
EI546_06930	ENOG4105EYH	Exonuclease
EI546_06940	ENOG4105CZH	peptidase
EI546_06945	ENOG4105DGW	oligopeptidase A
EI546_06955	ENOG4105D1Q	UPF0246 protein
EI546_06980	ENOG4105C5H	ABC transporter
EI546_06990	ENOG4105D05	Receptor
EI546_06995	ENOG4109066	lysm domain bon superfamily protein
EI546_07000	ENOG4107RKG	DJ-1/PfpI family
EI546_07005	ENOG4105CKW	Inner membrane protein yedI
EI546_07015	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
EI546_07020	ENOG4105CZH	peptidase
EI546_07095	ENOG4105CHU	acetyl-coa acetyltransferase
EI546_07105	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
EI546_07110	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EI546_07120	ENOG4105C84	Histidine ammonia-lyase
EI546_07125	ENOG4107ZT5	Thiol disulfide interchange protein
EI546_07130	ENOG4105CRE	cytochrome C
EI546_07155	ENOG4108Z03	MAF-like protein
EI546_07175	ENOG4107RJ1	sodium solute
EI546_07200	ENOG4108ETH	Formylglycinamide ribotide synthetase
EI546_07210	ENOG4108IQE	Amp-dependent synthetase and ligase
EI546_07220	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
EI546_07235	ENOG4105CHU	acetyl-coa acetyltransferase
EI546_07245	ENOG4105C1G	acyl-Coa dehydrogenase
EI546_07250	ENOG4105C34	Pseudouridine synthase
EI546_07260	ENOG4105CPF	Cell wall formation (By similarity)
EI546_07265	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EI546_07270	ENOG4107TT5	NLP P60 protein
EI546_07275	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
EI546_07285	ENOG4105DUX	Transporter
EI546_07290	ENOG4105DUX	Transporter
EI546_07295	ENOG4105DUX	Transporter
EI546_07305	ENOG4105CJW	magnesium transporter
EI546_07325	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
EI546_07335	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
EI546_07340	ENOG4108ZT0	50S ribosomal protein l17
EI546_07345	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EI546_07350	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
EI546_07355	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
EI546_07360	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EI546_07365	ENOG410864M	50S ribosomal protein L36
EI546_07370	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
EI546_07375	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
EI546_07380	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
EI546_07385	ENOG41084HK	50S ribosomal protein L30
EI546_07390	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
EI546_07395	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
EI546_07400	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
EI546_07405	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
EI546_07410	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
EI546_07415	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EI546_07420	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
EI546_07425	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
EI546_07430	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
EI546_07435	ENOG4105WNB	50s ribosomal protein l29
EI546_07440	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
EI546_07445	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
EI546_07450	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
EI546_07455	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
EI546_07460	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EI546_07465	ENOG41082S5	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
EI546_07470	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
EI546_07475	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
EI546_07480	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
EI546_07485	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
EI546_07490	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
EI546_07495	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
EI546_07505	ENOG4105C27	TonB-dependent Receptor Plug
EI546_07515	ENOG4105C2N	RNA methyltransferase TrmH family group 3
EI546_07525	ENOG4105D1H	recombination factor protein RarA
EI546_07545	ENOG4105W5Q	DNA repair protein (RadC
EI546_07575	ENOG4105KTH	gatB Yqey
EI546_07580	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
EI546_07585	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
EI546_07595	ENOG4105DFU	Cell wall formation (By similarity)
EI546_07600	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
EI546_07605	ENOG4105CNI	cell division protein FtsW
EI546_07610	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
EI546_07615	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
EI546_07620	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
EI546_07625	ENOG4105CJN	penicillin-binding protein
EI546_07635	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
EI546_07640	ENOG4107YM1	mraZ protein
EI546_07650	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
EI546_07670	ENOG4107RW9	nh(3)-dependent nad( ) synthetase
EI546_07675	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
EI546_07690	ENOG4105EMN	RNA polymerase sigma factor
EI546_07695	ENOG4105EAH	synthase
EI546_07700	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EI546_07710	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
EI546_07725	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
EI546_07740	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
EI546_07745	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
EI546_07755	ENOG4105DJV	ribulose-phosphate 3-epimerase
EI546_07760	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
EI546_07770	ENOG4105C27	TonB-dependent Receptor Plug
EI546_07800	ENOG4105C59	p-type ATPase
EI546_07810	ENOG4108IJF	Heavy metal efflux pump, CzcA
EI546_07855	ENOG4105DC1	bifunctional purine biosynthesis protein purh
EI546_07860	ENOG4105DFF	Rod shape-determining protein mreb
EI546_07875	ENOG4105CJN	penicillin-binding protein
EI546_07880	ENOG4105CNI	cell division protein FtsW
EI546_07890	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EI546_07895	ENOG4105CN1	protease
EI546_07900	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
EI546_07910	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
EI546_07915	ENOG4105RA3	Binds directly to 16S ribosomal RNA (By similarity)
EI546_07925	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
EI546_07945	ENOG4105EUJ	GTP cyclohydrolase i
EI546_07955	ENOG4105C8N	cysteinyl-tRNA synthetase
EI546_07960	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
EI546_07965	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
EI546_07975	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
EI546_08010	ENOG4107QZF	nitrite reductase NADPH large subunit
EI546_08015	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
EI546_08030	ENOG410838F	Glycosyl transferase family 2
EI546_08035	ENOG4105CND	Glycosyl transferase, family 2
EI546_08040	ENOG4105DFU	Cell wall formation (By similarity)
EI546_08055	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EI546_08060	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
EI546_08080	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
EI546_08115	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
EI546_08145	ENOG4105MIR	Phenylalanine 4-monooxygenase
EI546_08155	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
EI546_08160	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
EI546_08175	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
EI546_08185	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
EI546_08195	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
EI546_08220	ENOG4108UKI	Enoyl-CoA hydratase
EI546_08225	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
EI546_08245	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
EI546_08250	ENOG4105CGZ	zinc metallopeptidase
EI546_08260	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
EI546_08270	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
EI546_08280	ENOG4105DGW	oligopeptidase A
EI546_08310	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EI546_08315	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
EI546_08335	ENOG4105G6Z	alkaline phosphatase
EI546_08345	ENOG4105DHJ	ABC, transporter
EI546_08355	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
EI546_08390	ENOG4105KG3	cytidine deaminase
EI546_08410	ENOG4105E6M	Sulphatase-modifying factor protein
EI546_08415	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
EI546_08425	ENOG4108JYZ	YitT family
EI546_08475	ENOG4105C2C	drug resistance transporter, Bcr CflA
EI546_08495	ENOG4109015	Biopolymer transport protein exbD tolR
EI546_08520	ENOG4105C1G	acyl-Coa dehydrogenase
EI546_08530	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
EI546_08550	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
EI546_08570	ENOG4105VPI	YqaE family transport protein
EI546_08575	ENOG4105CRK	lysyL-tRNA synthetase
EI546_08590	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
EI546_08595	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
EI546_08600	ENOG4105K6H	D-cysteine desulfhydrase
EI546_08610	ENOG4107QM5	aconitate hydratase
EI546_08625	ENOG4108UVJ	appr-1-p processing domain protein
EI546_08645	ENOG4105CBX	hi0933 family
EI546_08650	ENOG4105DY8	decarboxylase
EI546_08680	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
EI546_08725	ENOG4105C5H	ABC transporter
EI546_08755	ENOG4105E6M	Sulphatase-modifying factor protein
EI546_08760	ENOG41088SP	formiminoglutamate hydrolase
EI546_08775	ENOG4105K5M	30s ribosomal protein S16
EI546_08780	ENOG4107YAY	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
EI546_08785	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
EI546_08810	ENOG4105CAY	ferredoxin--nadp reductase
EI546_08825	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
EI546_08835	ENOG4107UGT	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
EI546_08840	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
EI546_08845	ENOG4105BZU	Histidine kinase
EI546_08850	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EI546_09005	ENOG4105C8T	Leucyl-tRNA synthetase
EI546_09010	ENOG4107RJ9	Cell division protein FtsX
EI546_09020	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
EI546_09050	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
EI546_09060	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
EI546_09065	ENOG4107VPC	Peptidyl-arginine deiminase
EI546_09070	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
EI546_09080	ENOG4107XWI	flavin reductase domain protein, FMN-binding
EI546_09085	ENOG4105BZU	Histidine kinase
EI546_09100	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
EI546_09115	ENOG4105BZU	Histidine kinase
EI546_09130	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
EI546_09155	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
EI546_09165	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
EI546_09175	ENOG4105CHM	Aminotransferase
EI546_09180	ENOG4105CM2	brancheD-chain amino acid aminotransferase
EI546_09190	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
EI546_09200	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
EI546_09205	ENOG4107RWD	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
EI546_09210	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
EI546_09225	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
EI546_09230	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
EI546_09240	ENOG4105E0R	Deoxyhypusine synthase
EI546_09255	ENOG4105FE9	pseudouridine synthase
EI546_09290	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
EI546_09300	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
EI546_09315	ENOG4105ISI	outer membrane protein, OMPP1 FadL TodX family
EI546_09325	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
EI546_09335	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
EI546_09345	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
EI546_09350	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EI546_09370	ENOG4108Z0R	Transferase
EI546_09380	ENOG41083MR	nifu domain-containing protein
EI546_09390	ENOG4105C7Z	Conserved Protein
EI546_09395	ENOG4105D64	Mechanosensitive ion channel
EI546_09415	ENOG41072GX	Peptidase M22 Glycoprotease
EI546_09420	ENOG4105Y49	secretion protein, HlyD family
EI546_09435	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
EI546_09445	ENOG4105C19	ABC transporter
EI546_09455	ENOG4108SJC	Membrane
EI546_09480	ENOG4105CCU	oxidase (Subunit III)
EI546_09485	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
EI546_09515	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
EI546_09525	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
EI546_09695	ENOG4105C6K	Malic enzyme
EI546_09705	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
EI546_09710	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
EI546_09715	ENOG4105BZ9	Cytochrome C oxidase, subunit I
EI546_09720	ENOG4105E2S	oxidase) subunit II
EI546_09740	ENOG4105CE9	30S ribosomal protein S2
EI546_09745	ENOG4107SFQ	iron-sulfur binding
EI546_09750	ENOG4105NXP	Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis (By similarity)
EI546_09760	ENOG4105I6B	RNA polymerase
EI546_09795	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
EI546_09800	ENOG4105CHV	Transcription elongation factor NusA
EI546_09805	ENOG41090IP	Required for maturation of 30S ribosomal subunits (By similarity)
EI546_09810	ENOG4107YZX	Universal stress protein
EI546_09820	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
EI546_09825	ENOG4107PU6	Membrane
EI546_09835	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
EI546_09860	ENOG4105BZU	Histidine kinase
EI546_09865	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EI546_09875	ENOG4105D82	Glutamate dehydrogenase
EI546_09880	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
EI546_09890	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
EI546_09895	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
EI546_09900	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
EI546_09905	ENOG4105HMI	Membrane
EI546_09910	ENOG4105DUM	transcriptional regulator, lysR family
EI546_09915	ENOG4105D64	Mechanosensitive ion channel
EI546_09960	ENOG4107ZQV	short-chain dehydrogenase reductase
EI546_09995	ENOG4105D0S	secretion protein (HlyD
EI546_10005	ENOG4108W3Q	Transcriptional regulator
EI546_10035	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
EI546_10050	ENOG4105VT2	5-hydroxyisourate hydrolase
EI546_10065	ENOG4107ZT5	Thiol disulfide interchange protein
EI546_10075	ENOG4105C27	TonB-dependent Receptor Plug
EI546_10095	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
EI546_10100	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
EI546_10145	ENOG4105DZP	Membrane-associated zinc metalloprotease
EI546_10155	ENOG4108KF3	Electron transport protein SCO1 SenC
EI546_10165	ENOG4105CE1	Ferrous iron transport protein b
EI546_10180	ENOG4107RBD	ABC, transporter
EI546_10185	ENOG4107RPQ	ABC transporter
EI546_10190	ENOG4105DIK	(ABC) transporter
EI546_10195	ENOG4105DSE	periplasmic solute binding protein
EI546_10200	ENOG4107RPQ	ABC transporter
EI546_10205	ENOG4105D05	Receptor
EI546_10220	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EI546_10225	ENOG4108Y6J	UPF0403 protein
EI546_10275	ENOG4105CMQ	Chloride channel
EI546_10305	ENOG4108ZMR	Ion transport 2 domain-containing protein
EI546_10310	ENOG4105DZR	Type I site-specific deoxyribonuclease
EI546_10340	ENOG4105CVR	type I restriction-modification system
EI546_10350	ENOG4105VN1	Heat shock protein
EI546_10360	ENOG4105E39	Enoyl-CoA hydratase
EI546_10370	ENOG4105ES5	Histidine kinase
EI546_10390	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
EI546_10400	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
EI546_10405	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
EI546_10425	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
EI546_10435	ENOG4105EXN	Sulfate transport protein CysZ
EI546_10465	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
EI546_10470	ENOG4105VHG	atp synthase
EI546_10475	ENOG4107Z65	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
EI546_10480	ENOG4107Z4P	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
EI546_10485	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
EI546_10495	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
EI546_10505	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
EI546_10515	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
EI546_10520	ENOG4105EMU	Dehydrogenase
EI546_10525	ENOG4105CKK	Glycosyl transferase, family 2
EI546_10560	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
EI546_10565	ENOG4105BZ1	(ABC) transporter
EI546_10585	ENOG4105VG1	fes assembly suf system protein
EI546_10590	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
EI546_10595	ENOG4105C9B	Cysteine desulfurase
EI546_10620	ENOG4108Z4V	iron-sulfur cluster assembly
EI546_10625	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
EI546_10630	ENOG4108MUZ	hydrolase
EI546_10635	ENOG4107RAQ	aminopeptidase
EI546_10640	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
EI546_10650	ENOG4105MJ2	Competence protein
EI546_10675	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
EI546_10680	ENOG4105C72	UPF0176 protein
EI546_10685	ENOG4105MA4	psp1 domain protein
EI546_10690	ENOG410647Z	gliding motility-associated lipoprotein GldH
EI546_10695	ENOG4108JQC	penicillin-binding protein 1A
EI546_10700	ENOG4107QP7	CoA-transferase subunit A
EI546_10710	ENOG4108JQ6	ABC transporter
EI546_10750	ENOG4105D52	delta-aminolevulinic acid dehydratase
EI546_10755	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
EI546_10770	ENOG4105DVP	Adenine-specific
EI546_10805	ENOG4107QNG	Phosphoribosylglycinamide synthetase
EI546_10810	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
EI546_10845	ENOG4108UW5	maltose o-acetyltransferase
EI546_10850	ENOG4105CG5	Glycosyl transferase (Group 1
EI546_10895	ENOG4105PSV	Polysaccharide Biosynthesis Protein
EI546_10900	ENOG4107TYR	Glycosyl Transferase
EI546_10915	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
EI546_10935	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
EI546_10950	ENOG4108K5P	(LipO)protein
EI546_10955	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
EI546_10965	ENOG4105E9H	Lytic Murein transglycosylase
EI546_10970	ENOG4105BZA	Phosphoglycerate kinase
EI546_10985	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
EI546_10990	ENOG41080AX	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
EI546_11000	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
EI546_11015	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EI546_11125	ENOG4105CFH	Aspartokinase
EI546_11135	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EI546_11140	ENOG4106MAR	Phosphate-selective porin O and P
EI546_11155	ENOG4105CJW	magnesium transporter
EI546_11160	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
EI546_11185	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
EI546_11195	ENOG4105CN1	protease
EI546_11225	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
EI546_11235	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
EI546_11240	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
EI546_11245	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
EI546_11250	ENOG4105WXV	50S ribosomal protein L32
EI546_11260	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
EI546_11265	ENOG4108R6K	riboflavin synthase, subunit alpha
EI546_11305	ENOG4108ZVT	methylmalonyl-coA epimerase
EI546_11310	ENOG4105H4N	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
EI546_11315	ENOG4105D60	lipoprotein releasing system transmembrane protein
EI546_11325	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
EI546_11335	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
EI546_11345	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
EI546_11350	ENOG4105C8F	Beta-lactamase domain protein
EI546_11365	ENOG4105WG6	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
EI546_11370	ENOG4105CN1	protease
EI546_11390	ENOG4108YZG	isomerase
EI546_11400	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
EI546_11420	ENOG4105CX6	glutaminyL-tRNA synthetase
EI546_11445	ENOG4105E2Y	ABC, transporter
EI546_11460	ENOG4105YES	addiction module antidote protein
EI546_11465	ENOG4105VUH	addiction module killer protein
EI546_11475	ENOG4105VMP	Transcriptional regulator
EI546_11535	ENOG4108JQ1	Dehydrogenase
EI546_11550	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
EI546_11565	ENOG4105EMU	Dehydrogenase
EI546_11570	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
EI546_11610	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
EI546_11615	ENOG4108ZG0	Ompa motb domain protein
EI546_11645	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
EI546_11660	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
EI546_11670	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
EI546_11675	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
EI546_11680	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
EI546_11685	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
EI546_11710	ENOG4105M08	Membrane
EI546_11715	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
EI546_11730	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
EI546_11735	ENOG4105CD3	dihydroorotase
EI546_11750	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
EI546_11755	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
EI546_11780	ENOG4105VMP	Transcriptional regulator
EI546_11805	ENOG4108JA2	transcriptioN-repair coupling factor
EI546_11830	ENOG41080R2	UPF0102 protein
EI546_11845	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
EI546_11850	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
EI546_11870	ENOG4105BZM	domain protein
EI546_11910	ENOG4105C03	ribonuclease
EI546_11915	ENOG4105K70	DNA-binding protein
EI546_11920	ENOG4105CEN	a g-specific adenine glycosylase
EI546_11925	ENOG4108UUM	single-stranded DNA-binding protein
EI546_11930	ENOG4105C37	(CBS) domain
EI546_11955	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
EI546_11960	ENOG4105K46	50S ribosomal protein l27
EI546_11975	ENOG4105E33	succinate dehydrogenase
EI546_12010	ENOG4105CGK	Exodeoxyribonuclease III
EI546_12015	ENOG4105C26	Dehydrogenase
EI546_12030	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
EI546_12035	ENOG4105D44	asparaginase
EI546_12040	ENOG4105DN3	alpha-2-macroglobulin domain protein
EI546_12045	ENOG41082IR	Excinuclease ABC C subunit domain protein
EI546_12050	ENOG4108JQB	penicillin-binding protein 1C
EI546_12070	ENOG410624X	efflux transporter, rnd family, mfp subunit
EI546_12080	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
EI546_12090	ENOG4105E2D	ec 3.2.1.52
EI546_12095	ENOG4106N3A	copper homeostasis protein cutc
EI546_12100	ENOG41080ZE	Adenylate cyclase
EI546_12105	ENOG4108R5S	membrane
EI546_12140	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
EI546_12145	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
EI546_12150	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
EI546_12155	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
EI546_12160	ENOG4108B1Q	Ribonuclease
EI546_12170	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
EI546_12180	ENOG4105C31	Tryptophanyl-tRNA synthetase
EI546_12200	ENOG4108J3C	UTP-glucose-1-phosphate uridylyltransferase
EI546_12205	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
EI546_12215	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
EI546_12225	ENOG4105DTN	riboflavin biosynthesis protein ribF
EI546_12230	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
EI546_12235	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
EI546_12250	ENOG4107T8J	thymidine kinase
EI546_12255	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
EI546_12260	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
EI546_12265	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
EI546_12270	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
EI546_12300	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
EI546_12305	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
EI546_12310	ENOG4105DSJ	YicC domain protein
EI546_12340	ENOG4105C28	cystathionine
EI546_12355	ENOG41060VI	Involved in DNA repair and RecF pathway recombination (By similarity)
EI546_12360	ENOG41090A1	ferritin
EI546_12375	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
EI546_12380	ENOG41066YJ	Beta-lactamase
EI546_12385	ENOG4105DFA	alanine racemase domain protein
EI546_12405	ENOG4105C9K	Endothelin-converting enzyme 1
EI546_12420	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
EI546_12435	ENOG4108UUM	single-stranded DNA-binding protein
EI546_12445	ENOG4105C9U	ATP-dependent DNA helicase RecQ
EI546_12460	ENOG4105EMN	RNA polymerase sigma factor
EI546_12475	ENOG4105CFP	Peptidase U32
EI546_12490	ENOG4107QRT	dEAD DEAH box helicase
EI546_12495	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
EI546_12500	ENOG4107T0X	DNA ligase
EI546_12520	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
EI546_12525	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
EI546_12530	ENOG4108Z6B	deaminase
EI546_12535	ENOG4105VEQ	Cold shock protein
EI546_12545	ENOG4105C9M	aspartyl-trna synthetase
EI546_12550	ENOG4105BZS	acriflavin resistance protein
EI546_12580	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
EI546_12585	ENOG4105C7S	Dehydrogenase
EI546_12590	ENOG4105WH1	Two component transcriptional regulator luxr family
EI546_12595	ENOG4105BZU	Histidine kinase
EI546_12605	ENOG4105F8V	Hydrolase, tatD family
EI546_12610	ENOG4105HDK	L-asparaginase
EI546_12650	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EI546_12655	ENOG4105C5S	asparaginyl-tRNA synthetase
EI546_12670	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
EI546_12675	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
EI546_12680	ENOG4105E4C	Lytic transglycosylase catalytic
EI546_12735	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
EI546_12740	ENOG4105CE9	30S ribosomal protein S2
EI546_12745	ENOG4108UJD	30S ribosomal protein S9
EI546_12750	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
EI546_12755	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
EI546_12790	ENOG4105C2M	dna polymerase I
EI546_12795	ENOG4105D44	asparaginase
EI546_12800	ENOG4105DDG	Cyanophycinase
EI546_12805	ENOG4107RRY	Cyanophycin synthetase
EI546_12845	ENOG4105CWX	Alpha-1,2-mannosidase
EI546_12855	ENOG4105K63	Thioredoxin
EI546_12860	ENOG4108ZJ4	polysaccharide deacetylase
EI546_12880	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
EI546_12895	ENOG4107T7F	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
EI546_12910	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
EI546_12920	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
EI546_12925	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
EI546_12930	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
EI546_12935	ENOG4108S4H	thioesterase Superfamily protein
EI546_12945	ENOG4105C79	DNA protecting protein DprA
EI546_12950	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
EI546_12955	ENOG4107UFZ	Cyclic nucleotide-binding protein
EI546_12965	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
EI546_13020	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
EI546_13025	ENOG4105C1G	acyl-Coa dehydrogenase
EI546_13050	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
EI546_13055	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
EI546_13075	ENOG4108JU7	Transcriptional regulator
EI546_13080	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
EI546_13085	ENOG4105C0B	DNA polymerase III (alpha subunit)
EI546_13095	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
EI546_13100	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
EI546_13120	ENOG4105CVR	type I restriction-modification system
EI546_13155	ENOG4107QKA	exodeoxyribonuclease V beta
EI546_13165	ENOG4105S64	Formate nitrite transporter
EI546_13190	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
EI546_13240	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
EI546_13245	ENOG4105EYW	Ion transport protein
EI546_13250	ENOG4105CSA	Coproporphyrinogen iii oxidase
EI546_13265	ENOG4105MSB	protein, conserved in bacteria
EI546_13270	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
EI546_13300	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
EI546_13310	ENOG4105GR3	Histidine kinase
EI546_13315	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EI546_13350	ENOG4105DEN	Luciferase family
EI546_13355	ENOG4105E0Y	RtcB Protein
EI546_13445	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
EI546_13460	ENOG4105DZR	Type I site-specific deoxyribonuclease
EI546_13475	ENOG4107R3N	Filamentation induced by cAMP protein fic
EI546_13480	ENOG4105CVR	type I restriction-modification system
EI546_13515	ENOG4105CPP	Dehydrogenase, E1 component
EI546_13530	ENOG4105BZU	Histidine kinase
EI546_13550	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EI546_13555	ENOG4105DEN	Luciferase family
EI546_13560	ENOG4105W87	Cbs domain
EI546_13565	ENOG4107VXZ	Hydrolase
EI546_13575	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
EI546_13590	ENOG4105FDF	Could be involved in DNA repair (By similarity)
EI546_13595	ENOG4105DQE	DNA ligase
EI546_13630	ENOG4105EAH	synthase
EI546_13635	ENOG4105P52	geranylgeranyl reductase
EI546_13650	ENOG4108SEK	ompa motb domain protein
EI546_13665	ENOG4105CDY	transcriptional regulatory protein
EI546_13690	ENOG4105CFI	type iii restriction protein res subunit
EI546_13695	ENOG4105M6F	mutator MutT protein
EI546_13700	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
EI546_13780	ENOG4105D64	Mechanosensitive ion channel
EI546_13785	ENOG4105CUB	amino acid
EI546_13810	ENOG4105DDQ	anthranilate synthase
EI546_13815	ENOG41082J7	Rhodanese domain protein
EI546_13820	ENOG4105C72	UPF0176 protein
EI546_13855	ENOG4105C75	arginyL-tRNA synthetase
EI546_13865	ENOG41077A9	carbonic anhydrase
EI546_13870	ENOG4108MR6	WD40-like Beta Propeller Repeat
EI546_13880	ENOG4105EMN	RNA polymerase sigma factor
EI546_13890	ENOG4105C1J	atp-dependent rna helicase
EI546_13930	ENOG4105C26	Dehydrogenase
EI546_13935	ENOG4105C5Z	peptidase
EI546_13950	ENOG4105KPY	Small multidrug resistance protein
EI546_13955	ENOG4105CPC	Aldo Keto reductase
EI546_13970	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
EI546_14005	ENOG4105D7A	ATP-binding protein
EI546_14010	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
EI546_14020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EI546_14035	ENOG4105CKK	Glycosyl transferase, family 2
EI546_14050	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
EI546_14075	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
EI546_14090	ENOG4105K78	MarR family Transcriptional regulator
EI546_14095	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
EI546_14100	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
EI546_14105	ENOG4105C37	(CBS) domain
EI546_14130	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
EI546_14145	ENOG4105F0N	pyrophosphate phospho-hydrolase
EI546_14150	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EI546_14165	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
EI546_14170	ENOG4105DXM	phenylacetic acid degradation protein
EI546_14190	ENOG4105DHU	Bile acid
EI546_14195	ENOG4105NQC	Flavodoxin
EI546_14230	ENOG4105CPP	Dehydrogenase, E1 component
EI546_14260	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
EI546_14275	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
EI546_14325	ENOG4108U5N	UPF0316 protein
EI546_14340	ENOG4108V0P	LemA family
EI546_14350	ENOG4105DR5	peptidase
EI546_14355	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
EI546_14390	ENOG4105WH1	Two component transcriptional regulator luxr family
EI546_14410	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
EI546_14415	ENOG4108UKZ	OsmC family
EI546_14435	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
EI546_14450	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EI546_14475	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
EI546_14480	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
EI546_14485	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
EI546_14490	ENOG4105D2N	Aldolase
EI546_14500	ENOG4108RWN	rrna methyltransferase
EI546_14510	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EI546_14515	ENOG4105C1A	potassium transporter peripheral membrane
EI546_14520	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
EI546_14535	ENOG4105CHM	Aminotransferase
EI546_14545	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
EI546_14570	ENOG4107ZT5	Thiol disulfide interchange protein
EI546_14590	ENOG4105NWN	ApaG protein
EI546_14605	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EI546_14610	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EI546_14615	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EI546_14620	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EI546_14630	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EI546_14645	ENOG4105CJ2	(LipO)protein
EI546_14655	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EI546_14680	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
EI546_14690	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
EI546_14705	ENOG4105DY9	regulatoR
EI546_14710	ENOG4105C2F	Histidine kinase
EI546_14750	ENOG4108JPV	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
EI546_14755	ENOG4105VRT	cytoplasmic protein
EI546_14770	ENOG4107X35	defense response to bacterium
EI546_14775	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
EI546_14780	ENOG41074B2	UPF0747 protein
EI546_14845	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
EI546_14850	ENOG4105CAK	Cell division ATP-binding protein ftsE
EI546_14885	ENOG4105RAK	Histidine kinase
EI546_14905	ENOG4105ENH	Sulfatase
EI546_14910	ENOG4105EUZ	Beta-lactamase domain protein
EI546_14920	ENOG4105E6M	Sulphatase-modifying factor protein
EI546_14925	ENOG4105EFZ	amidohydrolase
EI546_14960	ENOG4105EHZ	conserved protein UCP016719
EI546_14965	ENOG4107R34	abc transporter permease protein
EI546_15005	ENOG4105BZG	amino acid carrier protein
EI546_15015	ENOG4105C1G	acyl-Coa dehydrogenase
EI546_15050	ENOG4108HRK	Histidine kinase
EI546_15065	ENOG4105DY9	regulatoR
EI546_15095	ENOG4105CRQ	synthase (Component I)
EI546_15110	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
EI546_15115	ENOG4105CTQ	phosphohexokinase
EI546_15130	ENOG4105C0P	Mg chelatase subunit ChlI
EI546_15140	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EI546_15145	ENOG4105EB3	Histidine kinase
EI546_15215	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
EI546_15225	ENOG4105CMR	udp-glucose 4-epimerase
EI546_15250	ENOG4108Z9K	Osmotically inducible protein
EI546_15275	ENOG4105FGM	Fructosamine kinase
EI546_15280	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
EI546_15300	ENOG41067HS	methyltransferase
EI546_15305	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
EI546_15315	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
EI546_15320	ENOG4105D9N	nucleoside
EI546_15330	ENOG4105C10	Electron transfer flavoprotein
EI546_15335	ENOG4105BZJ	Electron transfer flavoprotein
EI546_15360	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
EI546_15365	ENOG4107V1M	polysaccharide export protein
EI546_15370	ENOG4105D75	Capsular exopolysaccharide family
EI546_15380	ENOG4105DF9	Lipoate-protein, ligase
EI546_15395	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
EI546_15405	ENOG4105CDV	Ompa motb domain protein
EI546_15420	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
EI546_15425	ENOG4105IU0	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EI546_15435	ENOG4107QI1	Mate efflux family protein
EI546_15475	ENOG4108ZHJ	Organic hydroperoxide resistance protein
EI546_15550	ENOG4105EMN	RNA polymerase sigma factor
EI546_15555	ENOG4105BZ1	(ABC) transporter
EI546_15565	ENOG4105CKK	Glycosyl transferase, family 2
EI546_15575	ENOG41081WG	50s ribosomal protein l31
EI546_15600	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
EI546_15630	ENOG4105VG0	50S ribosomal protein l34
EI546_15635	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
EI546_15660	ENOG4105E0A	ABC, transporter
EI546_15665	ENOG4105EHG	Permease protein
EI546_15690	ENOG4105GFR	rna polymerase sigma factor
EI546_15710	ENOG4107QTF	adenylosuccinate lyase
EI546_15715	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EI546_15725	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
EI546_15735	ENOG4107SBE	Glycosyl transferase (Group 1
EI546_15745	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
EI546_15760	ENOG4105DJV	ribulose-phosphate 3-epimerase
EI546_15765	ENOG4107R1Y	fructose-bisphosphate aldolase
EI546_15785	ENOG4105CV1	Transketolase (EC 2.2.1.1)
EI546_15790	ENOG4108YZG	isomerase
EI546_15795	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
EI546_15800	ENOG4107VXZ	Hydrolase
EI546_15805	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
EI546_15820	ENOG4107QP8	phosphohexose isomerase
EI546_15835	ENOG4105DG6	mannose-6-phosphate isomerase
EI546_15845	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
EI546_15855	ENOG4105VDW	Csbd family
EI546_15860	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
EI546_15875	ENOG4106VK6	Flagellar motor protein
EI546_15880	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
EI546_15885	ENOG4105VJV	50s ribosomal protein L35
EI546_15890	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
EI546_15895	ENOG4105C22	threonyL-tRNA synthetase
EI546_15955	ENOG4105DBI	uridine monophosphokinase
EI546_15965	ENOG4105CMN	Methylmalonyl-coA mutase
EI546_15975	ENOG4105D5P	Methylmalonyl-coA mutase
EI546_15990	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
EI546_15995	ENOG4108RWN	rrna methyltransferase
EI546_16010	ENOG4105CIN	aminoacyl-histidine dipeptidase
EI546_16015	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
EI546_16025	ENOG4105SFS	phosphoesterase RecJ domain protein
EI546_16030	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
EI546_16050	ENOG4105C5H	ABC transporter