locus-tag	class	description
EI546_00010	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EI546_00020	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EI546_00045	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EI546_00055	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EI546_00065	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EI546_00070	COG0081	regulation of translation
EI546_00075	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EI546_00080	COG0222	ribosome binding
EI546_00085	COG0085	RNA polymerase activity
EI546_00090	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EI546_00110	COG0714	Associated with various cellular activities
EI546_00145	COG1704	LemA family
EI546_00155	COG0504	CTP synthase activity
EI546_00160	COG0706	membrane insertase activity
EI546_00170	COG0482	sulfurtransferase activity
EI546_00175	COG1404	Belongs to the peptidase S8 family
EI546_00190	COG1278	Cold shock
EI546_00195	COG0045	succinate-CoA ligase (ADP-forming) activity
EI546_00205	COG4325	translation initiation factor activity
EI546_00215	COG1187	pseudouridine synthase activity
EI546_00230	COG0556	nucleotide-excision repair
EI546_00240	COG2949	membrane
EI546_00255	COG1131	(ABC) transporter
EI546_00260	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EI546_00275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EI546_00305	COG1132	(ABC) transporter
EI546_00310	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EI546_00315	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EI546_00325	COG1862	Preprotein translocase
EI546_00330	COG0259	pyridoxamine-phosphate oxidase activity
EI546_00345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EI546_00350	COG3844	kynureninase activity
EI546_00380	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EI546_00385	COG1663	tetraacyldisaccharide 4'-kinase activity
EI546_00395	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EI546_00400	COG1595	DNA-templated transcription, initiation
EI546_00405	COG1216	Glycosyl transferase, family 2
EI546_00420	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EI546_00425	COG0436	Aminotransferase
EI546_00430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EI546_00440	COG0525	valine-tRNA ligase activity
EI546_00450	COG0688	phosphatidylethanolamine metabolic process
EI546_00455	COG4589	Belongs to the CDS family
EI546_00465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EI546_00470	COG0799	negative regulation of ribosome biogenesis
EI546_00485	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EI546_00490	COG0494	nUDIX hydrolase
EI546_00515	COG0101	tRNA pseudouridine synthase activity
EI546_00520	COG1132	(ABC) transporter
EI546_00525	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EI546_00530	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EI546_00550	COG0149	triose-phosphate isomerase activity
EI546_00555	COG2264	protein methyltransferase activity
EI546_00570	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EI546_00580	COG4628	conserved protein (DUF2132)
EI546_00590	COG0513	Belongs to the DEAD box helicase family
EI546_00595	COG0697	spore germination
EI546_00600	COG1064	alcohol dehydrogenase
EI546_00610	COG0598	Magnesium transport protein CorA
EI546_00655	COG3385	transposase activity
EI546_00705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EI546_00730	COG2732	(Barnase) inhibitor
EI546_00790	COG2996	Protein conserved in bacteria
EI546_00795	COG2032	superoxide dismutase activity
EI546_00835	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EI546_00870	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EI546_00880	COG0308	aminopeptidase N
EI546_00895	COG0069	glutamate synthase activity
EI546_00925	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EI546_00930	COG0210	DNA helicase
EI546_00935	COG0009	L-threonylcarbamoyladenylate synthase
EI546_00970	COG1575	Belongs to the MenA family. Type 1 subfamily
EI546_00975	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EI546_00980	COG4948	Mandelate Racemase Muconate Lactonizing
EI546_01005	COG0463	Glycosyl transferase, family 2
EI546_01005	COG1216	Glycosyl transferase, family 2
EI546_01015	COG0237	dephospho-CoA kinase activity
EI546_01030	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EI546_01035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EI546_01045	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EI546_01055	COG1250	3-hydroxyacyl-CoA dehydrogenase
EI546_01060	COG0673	inositol 2-dehydrogenase activity
EI546_01065	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EI546_01080	COG0628	permease
EI546_01125	COG4206	TonB-dependent receptor
EI546_01145	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EI546_01150	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EI546_01175	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EI546_01220	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EI546_01230	COG1295	ribonuclease BN
EI546_01240	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EI546_01245	COG0360	Binds together with S18 to 16S ribosomal RNA
EI546_01250	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EI546_01255	COG0359	binds to the 23S rRNA
EI546_01270	COG1136	(ABC) transporter
EI546_01270	COG0577	efflux transmembrane transporter activity
EI546_01275	COG0124	histidyl-tRNA synthetase
EI546_01280	COG3250	beta-galactosidase activity
EI546_01285	COG0280	phosphate acetyltransferase
EI546_01285	COG0857	belongs to the CobB CobQ family
EI546_01290	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EI546_01315	COG3279	Response regulator of the LytR AlgR family
EI546_01320	COG2205	protein histidine kinase activity
EI546_01335	COG0778	Nitroreductase
EI546_01345	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EI546_01355	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EI546_01355	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EI546_01390	COG1674	ftsk spoiiie
EI546_01415	COG0450	alkyl hydroperoxide reductase
EI546_01540	COG2050	protein possibly involved in aromatic compounds catabolism
EI546_01545	COG1169	isochorismate synthase
EI546_01550	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EI546_01560	COG1131	(ABC) transporter
EI546_01575	COG0484	heat shock protein binding
EI546_01595	COG0069	glutamate synthase activity
EI546_01625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EI546_01650	COG0589	response to stress
EI546_01655	COG0813	purine-nucleoside phosphorylase activity
EI546_01660	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EI546_01680	COG5002	protein histidine kinase activity
EI546_01685	COG0745	RESPONSE REGULATOR receiver
EI546_01755	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EI546_01780	COG1131	(ABC) transporter
EI546_01790	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
EI546_01815	COG0352	thiamine-phosphate diphosphorylase activity
EI546_01820	COG0513	Belongs to the DEAD box helicase family
EI546_01835	COG1629	transport
EI546_01835	COG4206	TonB-dependent receptor
EI546_01860	COG2234	aminopeptidase activity
EI546_01885	COG0732	type I restriction modification DNA specificity domain
EI546_01920	COG1960	acyl-CoA dehydrogenase activity
EI546_01950	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EI546_01985	COG0778	Nitroreductase
EI546_01995	COG1522	sequence-specific DNA binding
EI546_02015	COG1970	mechanosensitive ion channel activity
EI546_02020	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EI546_02030	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EI546_02035	COG1595	DNA-templated transcription, initiation
EI546_02055	COG2270	Major facilitator Superfamily
EI546_02070	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EI546_02075	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EI546_02080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EI546_02085	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EI546_02115	COG4974	Belongs to the 'phage' integrase family
EI546_02120	COG0656	L-ascorbic acid biosynthetic process
EI546_02125	COG1418	mRNA catabolic process
EI546_02155	COG1104	cysteine desulfurase activity
EI546_02175	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EI546_02190	COG1943	Transposase
EI546_02225	COG1028	Short-chain dehydrogenase reductase Sdr
EI546_02230	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EI546_02240	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EI546_02245	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EI546_02250	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EI546_02255	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EI546_02255	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EI546_02260	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EI546_02265	COG1078	dGTPase activity
EI546_02270	COG2204	response regulator
EI546_02275	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EI546_02280	COG0010	Belongs to the arginase family
EI546_02285	COG1228	amidohydrolase
EI546_02290	COG0589	response to stress
EI546_02295	COG0626	cystathionine gamma-synthase activity
EI546_02300	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EI546_02325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EI546_02325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EI546_02335	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EI546_02340	COG2972	Histidine kinase
EI546_02345	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EI546_02380	COG0488	(ABC) transporter
EI546_02400	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EI546_02405	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EI546_02410	COG0497	DNA recombination
EI546_02435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EI546_02445	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EI546_02450	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EI546_02465	COG1301	dicarboxylic acid transport
EI546_02470	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EI546_02475	COG0247	lactate metabolic process
EI546_02475	COG0277	FAD linked oxidase domain protein
EI546_02485	COG0438	transferase activity, transferring glycosyl groups
EI546_02495	COG1472	Belongs to the glycosyl hydrolase 3 family
EI546_02505	COG0247	lactate metabolic process
EI546_02505	COG2181	nitrate reductase activity
EI546_02515	COG2181	nitrate reductase activity
EI546_02515	COG0247	lactate metabolic process
EI546_02520	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EI546_02525	COG0860	N-Acetylmuramoyl-L-alanine amidase
EI546_02535	COG0251	oxidation-reduction process
EI546_02545	COG2890	protein-(glutamine-N5) methyltransferase activity
EI546_02555	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EI546_02555	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EI546_02560	COG0697	spore germination
EI546_02565	COG1739	Uncharacterized protein family UPF0029
EI546_02575	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EI546_02580	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EI546_02600	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EI546_02610	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EI546_02615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EI546_02630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EI546_02640	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EI546_02650	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EI546_02670	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EI546_02680	COG3956	TIGRFAM MazG family protein
EI546_02685	COG0300	oxidoreductase activity
EI546_02690	COG2094	Belongs to the DNA glycosylase MPG family
EI546_02735	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EI546_02740	COG0471	metal ion transport
EI546_02740	COG3273	potassium ion transport
EI546_02745	COG1360	Flagellar Motor Protein
EI546_02755	COG1028	Short-chain dehydrogenase reductase Sdr
EI546_02775	COG0443	Heat shock 70 kDa protein
EI546_02785	COG0587	DNA-directed DNA polymerase activity
EI546_02790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EI546_02790	COG1042	CoA-binding domain protein
EI546_02790	COG0045	succinate-CoA ligase (ADP-forming) activity
EI546_02810	COG4115	mRNA cleavage
EI546_02820	COG1074	ATP-dependent DNA helicase activity
EI546_02825	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EI546_02830	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EI546_02840	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EI546_02865	COG0714	Associated with various cellular activities
EI546_02870	COG3256	nitric oxide reductase
EI546_02875	COG2010	Cytochrome c
EI546_02905	COG0564	pseudouridine synthase activity
EI546_02910	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EI546_02945	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EI546_02990	COG0488	(ABC) transporter
EI546_03000	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EI546_03010	COG0242	peptide deformylase activity
EI546_03015	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EI546_03020	COG2171	N-acyltransferase activity
EI546_03035	COG1215	transferase activity, transferring glycosyl groups
EI546_03040	COG0463	Glycosyl transferase, family 2
EI546_03075	COG0617	tRNA 3'-terminal CCA addition
EI546_03080	COG1612	heme a metabolic process
EI546_03105	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EI546_03115	COG1475	DNA binding
EI546_03120	COG1192	Involved in chromosome partitioning
EI546_03125	COG1028	Short-chain dehydrogenase reductase Sdr
EI546_03150	COG0336	Belongs to the RNA methyltransferase TrmD family
EI546_03160	COG0640	Transcriptional regulator
EI546_03170	COG0335	large ribosomal subunit rRNA binding
EI546_03190	COG0415	Belongs to the DNA photolyase family
EI546_03200	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EI546_03220	COG0514	ATP-dependent DNA helicase (RecQ)
EI546_03225	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EI546_03250	COG0492	ferredoxin-NADP+ reductase activity
EI546_03255	COG0579	oxidoreductase
EI546_03285	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EI546_03335	COG5290	Psort location Cytoplasmic, score
EI546_03395	COG3385	transposase activity
EI546_03435	COG3385	transposase activity
EI546_03440	COG4974	Belongs to the 'phage' integrase family
EI546_03445	COG0517	IMP dehydrogenase activity
EI546_03545	COG1368	sulfuric ester hydrolase activity
EI546_03555	COG5002	protein histidine kinase activity
EI546_03560	COG0745	RESPONSE REGULATOR receiver
EI546_03620	COG1401	restriction endodeoxyribonuclease activity
EI546_03755	COG0300	oxidoreductase activity
EI546_03790	COG1846	Transcriptional regulator
EI546_03820	COG4977	sequence-specific DNA binding
EI546_03820	COG1917	Cupin 2, conserved barrel domain protein
EI546_03845	COG0562	UDP-galactopyranose mutase
EI546_03945	COG0802	atpase or kinase
EI546_03965	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EI546_04010	COG0022	dehydrogenase e1 component
EI546_04025	COG0813	purine-nucleoside phosphorylase activity
EI546_04035	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EI546_04040	COG1193	negative regulation of DNA recombination
EI546_04045	COG3011	Protein conserved in bacteria
EI546_04055	COG0302	gtp cyclohydrolase
EI546_04060	COG1136	(ABC) transporter
EI546_04070	COG2205	protein histidine kinase activity
EI546_04080	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EI546_04100	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EI546_04100	COG0321	lipoyl(octanoyl) transferase activity
EI546_04110	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EI546_04115	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EI546_04125	COG2326	polyphosphate kinase activity
EI546_04130	COG2204	response regulator
EI546_04140	COG1668	transmembrane transport
EI546_04145	COG4152	abc transporter atp-binding protein
EI546_04150	COG0484	heat shock protein binding
EI546_04155	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EI546_04165	COG1090	epimerase
EI546_04170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EI546_04170	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EI546_04180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EI546_04195	COG1215	transferase activity, transferring glycosyl groups
EI546_04225	COG1522	sequence-specific DNA binding
EI546_04240	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EI546_04240	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EI546_04240	COG1703	isobutyryl-CoA mutase activity
EI546_04260	COG0284	orotidine-5'-phosphate decarboxylase activity
EI546_04265	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EI546_04290	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EI546_04320	COG1278	Cold shock
EI546_04330	COG1335	isochorismatase
EI546_04335	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EI546_04375	COG1393	Belongs to the ArsC family
EI546_04385	COG0156	8-amino-7-oxononanoate synthase activity
EI546_04400	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EI546_04405	COG3385	transposase activity
EI546_04425	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EI546_04440	COG3422	double-strand break repair
EI546_04445	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EI546_04465	COG2353	YceI-like domain
EI546_04480	COG2217	Heavy metal translocating P-type atpase
EI546_04485	COG2814	Major facilitator Superfamily
EI546_04490	COG0668	transmembrane transport
EI546_04500	COG1012	belongs to the aldehyde dehydrogenase family
EI546_04505	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EI546_04510	COG2066	Belongs to the glutaminase family
EI546_04520	COG2154	pterin-4-alpha-carbinolamine dehydratase
EI546_04525	COG0217	transcriptional regulatory protein
EI546_04545	COG1454	alcohol dehydrogenase
EI546_04550	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EI546_04565	COG0116	Belongs to the methyltransferase superfamily
EI546_04565	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EI546_04575	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EI546_04585	COG0038	chloride channel
EI546_04590	COG0745	RESPONSE REGULATOR receiver
EI546_04590	COG2972	Histidine kinase
EI546_04595	COG3279	Response regulator of the LytR AlgR family
EI546_04600	COG1505	serine-type exopeptidase activity
EI546_04620	COG0006	proline dipeptidase activity
EI546_04635	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EI546_04650	COG1028	Short-chain dehydrogenase reductase Sdr
EI546_04670	COG0189	ligase activity
EI546_04675	COG2988	succinylglutamate desuccinylase activity
EI546_04680	COG0671	phosphoesterase, PA-phosphatase related
EI546_04685	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EI546_04695	COG0659	secondary active sulfate transmembrane transporter activity
EI546_04705	COG2226	methyltransferase
EI546_04725	COG0583	DNA-binding transcription factor activity
EI546_04730	COG2079	MmgE PrpD family protein
EI546_04740	COG0322	excinuclease ABC activity
EI546_04770	COG1252	NADH dehydrogenase
EI546_04780	COG1570	exodeoxyribonuclease VII activity
EI546_04785	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EI546_04820	COG2808	Putative FMN-binding domain
EI546_04850	COG1752	Esterase of the alpha-beta hydrolase superfamily
EI546_04855	COG2201	protein-glutamate methylesterase activity
EI546_04860	COG4251	negative regulation of phosphorylation
EI546_04865	COG3706	GGDEF domain
EI546_04865	COG0745	RESPONSE REGULATOR receiver
EI546_04875	COG0708	Exodeoxyribonuclease III
EI546_04890	COG1030	water channel activity
EI546_04895	COG0330	HflC and HflK could
EI546_04930	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EI546_04955	COG0450	alkyl hydroperoxide reductase
EI546_04970	COG1127	ABC transporter
EI546_04975	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EI546_05025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EI546_05035	COG0714	Associated with various cellular activities
EI546_05040	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EI546_05050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EI546_05075	COG0516	GMP reductase activity
EI546_05075	COG0517	IMP dehydrogenase activity
EI546_05100	COG0737	Belongs to the 5'-nucleotidase family
EI546_05105	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EI546_05115	COG1280	lysine exporter protein (LysE YggA)
EI546_05120	COG0167	dihydroorotate dehydrogenase activity
EI546_05125	COG2195	Cleaves the N-terminal amino acid of tripeptides
EI546_05130	COG2733	membrane
EI546_05135	COG1234	tRNA 3'-trailer cleavage
EI546_05145	COG0540	Belongs to the ATCase OTCase family
EI546_05150	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EI546_05175	COG0484	heat shock protein binding
EI546_05190	COG0012	GTP binding
EI546_05200	COG3340	Belongs to the peptidase S51 family
EI546_05210	COG1876	peptidase activity
EI546_05215	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EI546_05220	COG0552	protein localization to endoplasmic reticulum
EI546_05230	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EI546_05235	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EI546_05240	COG1058	Belongs to the CinA family
EI546_05240	COG1546	Belongs to the CinA family
EI546_05245	COG0179	Fumarylacetoacetate (FAA) hydrolase
EI546_05250	COG2176	DNA-directed DNA polymerase activity
EI546_05250	COG5002	protein histidine kinase activity
EI546_05255	COG0508	dehydrogenase complex catalyzes the overall conversion of
EI546_05265	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EI546_05275	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EI546_05285	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EI546_05290	COG1506	peptidase
EI546_05300	COG0326	Molecular chaperone. Has ATPase activity
EI546_05340	COG1482	cell wall glycoprotein biosynthetic process
EI546_05350	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EI546_05355	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EI546_05375	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EI546_05420	COG1363	Peptidase, m42
EI546_05425	COG1115	amino acid carrier protein
EI546_05435	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EI546_05440	COG1702	phosphate starvation-inducible protein PhoH
EI546_05465	COG0592	DNA-directed DNA polymerase activity
EI546_05480	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EI546_05610	COG1047	Peptidyl-prolyl cis-trans
EI546_05650	COG0348	domain, Protein
EI546_05675	COG2217	Heavy metal translocating P-type atpase
EI546_05700	COG4221	oxidoreductase activity
EI546_05705	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EI546_05730	COG2010	Cytochrome c
EI546_05740	COG1959	2 iron, 2 sulfur cluster binding
EI546_05755	COG0783	Belongs to the Dps family
EI546_05810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EI546_05815	COG2968	Membrane
EI546_05820	COG0705	Rhomboid family
EI546_05870	COG1181	Belongs to the D-alanine--D-alanine ligase family
EI546_05875	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EI546_05880	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EI546_05905	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EI546_05910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EI546_05950	COG0438	transferase activity, transferring glycosyl groups
EI546_05985	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EI546_06015	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EI546_06025	COG0175	sulfate reduction
EI546_06030	COG0529	Catalyzes the synthesis of activated sulfate
EI546_06040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EI546_06045	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EI546_06060	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EI546_06065	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EI546_06075	COG1760	l-serine dehydratase
EI546_06080	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EI546_06085	COG0564	pseudouridine synthase activity
EI546_06110	COG0590	tRNA wobble adenosine to inosine editing
EI546_06115	COG0511	ligase activity, forming carbon-carbon bonds
EI546_06115	COG5016	pyruvate
EI546_06120	COG0439	Biotin carboxylase
EI546_06125	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EI546_06155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EI546_06170	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EI546_06170	COG0116	Belongs to the methyltransferase superfamily
EI546_06175	COG2226	methyltransferase
EI546_06195	COG1086	Polysaccharide biosynthesis protein
EI546_06200	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EI546_06230	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EI546_06240	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EI546_06250	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EI546_06265	COG1136	(ABC) transporter
EI546_06330	COG0438	transferase activity, transferring glycosyl groups
EI546_06335	COG0438	transferase activity, transferring glycosyl groups
EI546_06340	COG0463	Glycosyl transferase, family 2
EI546_06340	COG1216	Glycosyl transferase, family 2
EI546_06345	COG1216	Glycosyl transferase, family 2
EI546_06345	COG0463	Glycosyl transferase, family 2
EI546_06355	COG0438	transferase activity, transferring glycosyl groups
EI546_06525	COG0740	serine-type endopeptidase activity
EI546_06655	COG3392	D12 class N6 adenine-specific DNA methyltransferase
EI546_06660	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EI546_06670	COG0405	Gamma-glutamyltransferase
EI546_06685	COG1611	Belongs to the LOG family
EI546_06715	COG0022	dehydrogenase e1 component
EI546_06725	COG0590	tRNA wobble adenosine to inosine editing
EI546_06730	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EI546_06740	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EI546_06755	COG0305	Participates in initiation and elongation during chromosome replication
EI546_06760	COG0825	malonyl-CoA metabolic process
EI546_06775	COG0343	queuine tRNA-ribosyltransferase activity
EI546_06780	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EI546_06785	COG3958	Transketolase
EI546_06800	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EI546_06805	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EI546_06815	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EI546_06820	COG0514	ATP-dependent DNA helicase (RecQ)
EI546_06825	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EI546_06825	COG0517	IMP dehydrogenase activity
EI546_06830	COG0805	protein transport
EI546_06840	COG1137	ATPase activity
EI546_06845	COG1183	phosphatidylcholine synthase activity
EI546_06865	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EI546_06880	COG0438	transferase activity, transferring glycosyl groups
EI546_06885	COG2096	Adenosyltransferase
EI546_06895	COG0653	protein targeting
EI546_06925	COG0420	3'-5' exonuclease activity
EI546_06930	COG0419	ATPase involved in DNA repair
EI546_06940	COG4717	serine-type aminopeptidase activity
EI546_06945	COG0339	signal peptide processing
EI546_06955	COG3022	response to hydroperoxide
EI546_06980	COG0488	(ABC) transporter
EI546_06990	COG4771	TonB-dependent receptor
EI546_06995	COG1652	LysM domain
EI546_07000	COG0693	protein deglycase activity
EI546_07005	COG2354	Protein conserved in bacteria
EI546_07015	COG0477	Major facilitator Superfamily
EI546_07020	COG3591	Belongs to the peptidase S1B family
EI546_07040	COG0628	permease
EI546_07095	COG0183	Belongs to the thiolase family
EI546_07105	COG3063	Type IV pilus biogenesis stability protein PilW
EI546_07110	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EI546_07115	COG0542	response to heat
EI546_07120	COG2986	histidine ammonia-lyase
EI546_07125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EI546_07130	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EI546_07130	COG1333	cytochrome c biogenesis protein
EI546_07155	COG0424	maF-like protein
EI546_07175	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EI546_07190	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EI546_07190	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EI546_07210	COG1022	Amp-dependent synthetase and ligase
EI546_07220	COG1846	Transcriptional regulator
EI546_07235	COG0183	Belongs to the thiolase family
EI546_07245	COG1960	acyl-CoA dehydrogenase activity
EI546_07250	COG0564	pseudouridine synthase activity
EI546_07260	COG1181	Belongs to the D-alanine--D-alanine ligase family
EI546_07265	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EI546_07270	COG0791	NLP P60 protein
EI546_07275	COG0658	competence protein
EI546_07275	COG2333	competence protein COMEC
EI546_07285	COG3104	oligopeptide transport
EI546_07290	COG3104	oligopeptide transport
EI546_07295	COG3104	oligopeptide transport
EI546_07305	COG2239	Acts as a magnesium transporter
EI546_07325	COG0148	phosphopyruvate hydratase activity
EI546_07335	COG0505	Belongs to the CarA family
EI546_07340	COG0203	ribosomal protein L17
EI546_07345	COG0202	RNA polymerase activity
EI546_07350	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EI546_07355	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EI546_07360	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EI546_07365	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EI546_07370	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EI546_07375	COG0201	protein transport
EI546_07380	COG0200	Binds to the 23S rRNA
EI546_07385	COG1841	ribosomal large subunit assembly
EI546_07390	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EI546_07395	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EI546_07400	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EI546_07405	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EI546_07410	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EI546_07415	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EI546_07420	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EI546_07425	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EI546_07430	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EI546_07435	COG0255	Belongs to the universal ribosomal protein uL29 family
EI546_07440	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EI546_07445	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EI546_07450	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EI546_07455	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EI546_07460	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EI546_07465	COG0089	rRNA binding
EI546_07470	COG0088	Forms part of the polypeptide exit tunnel
EI546_07475	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EI546_07480	COG0051	transcription antitermination factor activity, RNA binding
EI546_07485	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EI546_07490	COG0049	tRNA binding
EI546_07495	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EI546_07505	COG4206	TonB-dependent receptor
EI546_07505	COG1629	transport
EI546_07515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EI546_07525	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EI546_07545	COG2003	Belongs to the UPF0758 family
EI546_07575	COG1610	YqeY-like protein
EI546_07595	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EI546_07600	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EI546_07605	COG0772	Belongs to the SEDS family
EI546_07610	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EI546_07615	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EI546_07620	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EI546_07625	COG0768	penicillin binding
EI546_07635	COG0275	rRNA processing
EI546_07640	COG2001	Belongs to the MraZ family
EI546_07645	COG2267	carboxylic ester hydrolase activity
EI546_07650	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EI546_07670	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EI546_07675	COG0358	DNA primase activity
EI546_07690	COG1595	DNA-templated transcription, initiation
EI546_07695	COG0142	geranyltranstransferase activity
EI546_07700	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EI546_07710	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EI546_07725	COG1694	Mazg nucleotide pyrophosphohydrolase
EI546_07740	COG1490	D-aminoacyl-tRNA deacylase activity
EI546_07745	COG1162	GTPase activity
EI546_07755	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EI546_07760	COG0492	ferredoxin-NADP+ reductase activity
EI546_07770	COG4206	TonB-dependent receptor
EI546_07770	COG1629	transport
EI546_07780	COG3385	transposase activity
EI546_07800	COG2217	Heavy metal translocating P-type atpase
EI546_07810	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EI546_07855	COG0138	bifunctional purine biosynthesis protein purh
EI546_07860	COG1077	Cell shape determining protein MreB Mrl
EI546_07875	COG0768	penicillin binding
EI546_07880	COG0772	Belongs to the SEDS family
EI546_07890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EI546_07900	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EI546_07910	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EI546_07915	COG0268	Binds directly to 16S ribosomal RNA
EI546_07925	COG0442	prolyl-tRNA aminoacylation
EI546_07945	COG0302	gtp cyclohydrolase
EI546_07955	COG0215	cysteine-tRNA ligase activity
EI546_07960	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EI546_07965	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EI546_07975	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EI546_08010	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EI546_08015	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EI546_08035	COG1215	transferase activity, transferring glycosyl groups
EI546_08040	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EI546_08055	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EI546_08060	COG0563	adenylate kinase activity
EI546_08080	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EI546_08085	COG1428	Deoxynucleoside kinase
EI546_08115	COG0175	sulfate reduction
EI546_08145	COG3186	Phenylalanine-4-hydroxylase
EI546_08155	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EI546_08160	COG3396	Phenylacetate-CoA oxygenase
EI546_08175	COG3460	Phenylacetate-CoA oxygenase
EI546_08185	COG3396	Phenylacetate-CoA oxygenase
EI546_08195	COG2151	metal-sulfur cluster biosynthetic enzyme
EI546_08220	COG1024	Enoyl-CoA hydratase
EI546_08225	COG1250	3-hydroxyacyl-CoA dehydrogenase
EI546_08235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EI546_08235	COG0723	plastoquinol--plastocyanin reductase activity
EI546_08245	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EI546_08250	COG2321	neutral zinc metallopeptidase
EI546_08260	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EI546_08270	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EI546_08280	COG0339	signal peptide processing
EI546_08310	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EI546_08310	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EI546_08315	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EI546_08335	COG1785	Belongs to the alkaline phosphatase family
EI546_08340	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EI546_08345	COG1127	ABC transporter
EI546_08355	COG0662	Cupin 2, conserved barrel domain protein
EI546_08355	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EI546_08375	COG1028	Short-chain dehydrogenase reductase Sdr
EI546_08390	COG0295	cytidine deaminase activity
EI546_08410	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EI546_08415	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EI546_08425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EI546_08475	COG2814	Major facilitator Superfamily
EI546_08495	COG0848	biopolymer transport protein
EI546_08500	COG0811	peptide transport
EI546_08520	COG1960	acyl-CoA dehydrogenase activity
EI546_08530	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EI546_08550	COG0321	lipoyl(octanoyl) transferase activity
EI546_08570	COG0401	homolog of Blt101
EI546_08575	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EI546_08590	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EI546_08595	COG1705	Flagellar rod assembly protein muramidase FlgJ
EI546_08600	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EI546_08610	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EI546_08645	COG2081	HI0933 family
EI546_08650	COG0076	glutamate decarboxylase activity
EI546_08680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EI546_08715	COG1752	Esterase of the alpha-beta hydrolase superfamily
EI546_08725	COG0488	(ABC) transporter
EI546_08755	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EI546_08760	COG0010	Belongs to the arginase family
EI546_08775	COG0228	four-way junction DNA binding
EI546_08780	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EI546_08785	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EI546_08810	COG0492	ferredoxin-NADP+ reductase activity
EI546_08820	COG0489	protein tyrosine kinase activity
EI546_08825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EI546_08835	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EI546_08840	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EI546_08845	COG5002	protein histidine kinase activity
EI546_08850	COG0745	RESPONSE REGULATOR receiver
EI546_09000	COG2738	Putative neutral zinc metallopeptidase
EI546_09005	COG0495	leucyl-tRNA aminoacylation
EI546_09010	COG2177	Part of the ABC transporter FtsEX involved in
EI546_09020	COG1968	undecaprenyl-diphosphatase activity
EI546_09050	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EI546_09060	COG0519	Catalyzes the synthesis of GMP from XMP
EI546_09065	COG2957	Belongs to the agmatine deiminase family
EI546_09070	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EI546_09080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EI546_09085	COG4191	Histidine kinase
EI546_09100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EI546_09130	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EI546_09155	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EI546_09165	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EI546_09175	COG0436	Aminotransferase
EI546_09190	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EI546_09205	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EI546_09210	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EI546_09225	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EI546_09230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EI546_09230	COG3153	acetyltransferase
EI546_09240	COG1899	peptidyl-lysine modification to peptidyl-hypusine
EI546_09245	COG0010	Belongs to the arginase family
EI546_09255	COG1187	pseudouridine synthase activity
EI546_09265	COG1428	Deoxynucleoside kinase
EI546_09290	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EI546_09300	COG0544	peptidyl-prolyl cis-trans isomerase activity
EI546_09325	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EI546_09335	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EI546_09345	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EI546_09370	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EI546_09380	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EI546_09390	COG1331	Highly conserved protein containing a thioredoxin domain
EI546_09395	COG0668	transmembrane transport
EI546_09415	COG1214	PFAM Peptidase M22, glycoprotease
EI546_09420	COG1566	PFAM secretion protein HlyD family protein
EI546_09435	COG1136	(ABC) transporter
EI546_09435	COG0577	efflux transmembrane transporter activity
EI546_09445	COG1136	(ABC) transporter
EI546_09455	COG2322	membrane
EI546_09460	COG1999	signal sequence binding
EI546_09475	COG1845	cytochrome c oxidase, subunit III
EI546_09480	COG1845	cytochrome c oxidase, subunit III
EI546_09485	COG0109	protoheme IX farnesyltransferase activity
EI546_09515	COG0509	glycine decarboxylation via glycine cleavage system
EI546_09525	COG0632	four-way junction helicase activity
EI546_09560	COG4974	Belongs to the 'phage' integrase family
EI546_09605	COG4974	Belongs to the 'phage' integrase family
EI546_09705	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EI546_09710	COG2255	four-way junction helicase activity
EI546_09715	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EI546_09720	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EI546_09740	COG0052	Belongs to the universal ribosomal protein uS2 family
EI546_09745	COG0437	4 iron, 4 sulfur cluster binding
EI546_09765	COG3794	PFAM blue (type 1) copper domain protein
EI546_09795	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EI546_09800	COG0195	Participates in both transcription termination and antitermination
EI546_09805	COG0779	Required for maturation of 30S ribosomal subunits
EI546_09810	COG0589	response to stress
EI546_09820	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EI546_09825	COG3174	membrane
EI546_09835	COG4232	protein-disulfide reductase activity
EI546_09860	COG4191	Histidine kinase
EI546_09875	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EI546_09880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EI546_09890	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EI546_09900	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EI546_09905	COG2855	membrane
EI546_09915	COG0668	transmembrane transport
EI546_09930	COG0589	response to stress
EI546_09930	COG0475	glutathione-regulated potassium exporter activity
EI546_09935	COG1028	Short-chain dehydrogenase reductase Sdr
EI546_09960	COG1028	Short-chain dehydrogenase reductase Sdr
EI546_10005	COG2207	Transcriptional regulator
EI546_10035	COG1088	dTDP-glucose 4,6-dehydratase activity
EI546_10050	COG2351	hydroxyisourate hydrolase activity
EI546_10065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EI546_10075	COG4206	TonB-dependent receptor
EI546_10075	COG1629	transport
EI546_10095	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EI546_10100	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EI546_10100	COG1328	CTP reductase activity
EI546_10145	COG0750	zinc metalloprotease
EI546_10155	COG1999	signal sequence binding
EI546_10180	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EI546_10185	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EI546_10190	COG1121	(ABC) transporter
EI546_10195	COG0803	Belongs to the bacterial solute-binding protein 9 family
EI546_10200	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EI546_10200	COG1321	iron dependent repressor
EI546_10205	COG4771	TonB-dependent receptor
EI546_10240	COG1418	mRNA catabolic process
EI546_10275	COG0038	chloride channel
EI546_10310	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EI546_10340	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EI546_10350	COG0071	Belongs to the small heat shock protein (HSP20) family
EI546_10360	COG1024	Enoyl-CoA hydratase
EI546_10370	COG5000	phosphorelay sensor kinase activity
EI546_10390	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EI546_10400	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EI546_10405	COG0181	hydroxymethylbilane synthase activity
EI546_10410	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EI546_10425	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EI546_10435	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
EI546_10465	COG0356	it plays a direct role in the translocation of protons across the membrane
EI546_10470	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EI546_10475	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EI546_10480	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EI546_10485	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EI546_10495	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EI546_10505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EI546_10515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EI546_10520	COG4221	oxidoreductase activity
EI546_10525	COG0463	Glycosyl transferase, family 2
EI546_10550	COG3551	Protein conserved in bacteria
EI546_10560	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EI546_10565	COG1132	(ABC) transporter
EI546_10585	COG2151	metal-sulfur cluster biosynthetic enzyme
EI546_10590	COG2166	iron-sulfur cluster assembly
EI546_10600	COG0719	Fe-S assembly protein
EI546_10605	COG0396	ATPase activity
EI546_10615	COG0719	Fe-S assembly protein
EI546_10620	COG0316	Belongs to the HesB IscA family
EI546_10625	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EI546_10630	COG2267	carboxylic ester hydrolase activity
EI546_10635	COG0006	proline dipeptidase activity
EI546_10640	COG0423	glycine-tRNA ligase activity
EI546_10650	COG1040	competence protein
EI546_10675	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EI546_10685	COG1774	PSP1 C-terminal conserved region
EI546_10695	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EI546_10700	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EI546_10710	COG4172	Belongs to the ABC transporter superfamily
EI546_10750	COG0113	porphobilinogen synthase activity
EI546_10755	COG0408	coproporphyrinogen oxidase activity
EI546_10805	COG0151	Belongs to the GarS family
EI546_10815	COG1215	transferase activity, transferring glycosyl groups
EI546_10835	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EI546_10845	COG0110	maltose O-acetyltransferase activity
EI546_10850	COG0438	transferase activity, transferring glycosyl groups
EI546_10880	COG0463	Glycosyl transferase, family 2
EI546_10895	COG2244	polysaccharide biosynthetic process
EI546_10900	COG0438	transferase activity, transferring glycosyl groups
EI546_10950	COG4942	peptidase
EI546_10955	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EI546_10965	COG1388	LysM domain
EI546_10965	COG0741	lytic transglycosylase activity
EI546_10970	COG0126	phosphoglycerate kinase activity
EI546_10985	COG0445	tRNA wobble uridine modification
EI546_10990	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EI546_11000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EI546_11015	COG4974	Belongs to the 'phage' integrase family
EI546_11125	COG0527	aspartate kinase activity
EI546_11135	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EI546_11140	COG3746	phosphate-selective porin O and P
EI546_11155	COG2239	Acts as a magnesium transporter
EI546_11160	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EI546_11185	COG2095	MarC family integral membrane protein
EI546_11195	COG0793	Belongs to the peptidase S41A family
EI546_11215	COG1289	transmembrane transporter activity
EI546_11225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EI546_11235	COG0439	Biotin carboxylase
EI546_11240	COG0511	ligase activity, forming carbon-carbon bonds
EI546_11245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EI546_11250	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EI546_11260	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EI546_11265	COG0307	riboflavin synthase, alpha
EI546_11270	COG3385	transposase activity
EI546_11305	COG0346	lactoylglutathione lyase activity
EI546_11310	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EI546_11315	COG4591	ABC-type transport system involved in lipoprotein release permease component
EI546_11335	COG0481	GTPase activity
EI546_11345	COG3263	regulation of cellular component size
EI546_11350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EI546_11365	COG0594	ribonuclease P activity
EI546_11370	COG0793	Belongs to the peptidase S41A family
EI546_11390	COG0698	ribose 5-phosphate isomerase
EI546_11400	COG0557	exoribonuclease II activity
EI546_11420	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EI546_11445	COG1116	anion transmembrane transporter activity
EI546_11460	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EI546_11465	COG3657	addiction module killer protein
EI546_11475	COG3655	Transcriptional regulator
EI546_11535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EI546_11550	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EI546_11565	COG4221	oxidoreductase activity
EI546_11570	COG0714	Associated with various cellular activities
EI546_11585	COG2304	oxidoreductase activity
EI546_11610	COG0156	8-amino-7-oxononanoate synthase activity
EI546_11615	COG2885	chlorophyll binding
EI546_11645	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EI546_11660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EI546_11670	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EI546_11675	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EI546_11675	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EI546_11680	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EI546_11685	COG0720	synthase
EI546_11710	COG2363	Small membrane protein
EI546_11715	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EI546_11730	COG0463	Glycosyl transferase, family 2
EI546_11735	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EI546_11750	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EI546_11780	COG3655	Transcriptional regulator
EI546_11805	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EI546_11830	COG0792	nuclease activity
EI546_11845	COG1619	proteins homologs of microcin C7 resistance protein MccF
EI546_11850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EI546_11850	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EI546_11870	COG2183	response to ionizing radiation
EI546_11910	COG1530	ribonuclease E activity
EI546_11915	COG0776	regulation of translation
EI546_11920	COG1194	a g-specific adenine glycosylase
EI546_11925	COG0629	single-stranded DNA binding
EI546_11940	COG0612	Peptidase, M16
EI546_11945	COG0612	Peptidase, M16
EI546_11955	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EI546_11960	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EI546_11980	COG1053	succinate dehydrogenase
EI546_12010	COG0708	Exodeoxyribonuclease III
EI546_12015	COG1012	belongs to the aldehyde dehydrogenase family
EI546_12030	COG0662	Cupin 2, conserved barrel domain protein
EI546_12035	COG1446	asparaginase
EI546_12040	COG2373	Large extracellular alpha-helical protein
EI546_12045	COG2827	Endonuclease containing a URI domain
EI546_12050	COG4953	penicillin-binding protein 1C
EI546_12070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EI546_12080	COG1538	Outer membrane efflux protein
EI546_12090	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EI546_12105	COG3647	Membrane
EI546_12120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EI546_12130	COG0469	pyruvate kinase activity
EI546_12140	COG0571	ribonuclease III activity
EI546_12145	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EI546_12150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EI546_12155	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EI546_12160	COG0328	RNA-DNA hybrid ribonuclease activity
EI546_12160	COG3341	Caulimovirus viroplasmin
EI546_12180	COG0180	Tryptophanyl-tRNA synthetase
EI546_12200	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EI546_12205	COG0756	dUTP diphosphatase activity
EI546_12215	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EI546_12225	COG0196	riboflavin kinase activity
EI546_12230	COG0193	aminoacyl-tRNA hydrolase activity
EI546_12235	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EI546_12240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EI546_12250	COG1435	thymidine kinase activity
EI546_12255	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EI546_12260	COG1970	mechanosensitive ion channel activity
EI546_12265	COG0860	N-Acetylmuramoyl-L-alanine amidase
EI546_12270	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EI546_12280	COG1505	serine-type exopeptidase activity
EI546_12290	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EI546_12300	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EI546_12305	COG0194	GDP metabolic process
EI546_12310	COG1561	YicC-like family, N-terminal region
EI546_12340	COG0626	cystathionine gamma-synthase activity
EI546_12355	COG1381	Involved in DNA repair and RecF pathway recombination
EI546_12360	COG1528	Iron-storage protein
EI546_12365	COG0456	acetyltransferase
EI546_12375	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EI546_12380	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EI546_12385	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EI546_12405	COG3590	peptidase
EI546_12435	COG0629	single-stranded DNA binding
EI546_12460	COG1595	DNA-templated transcription, initiation
EI546_12475	COG0826	peptidase U32
EI546_12490	COG1201	RNA secondary structure unwinding
EI546_12495	COG2852	Protein conserved in bacteria
EI546_12500	COG1793	dna ligase
EI546_12515	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EI546_12520	COG1404	Belongs to the peptidase S8 family
EI546_12525	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EI546_12530	COG0590	tRNA wobble adenosine to inosine editing
EI546_12535	COG1278	Cold shock
EI546_12545	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EI546_12585	COG0508	dehydrogenase complex catalyzes the overall conversion of
EI546_12590	COG2197	response regulator
EI546_12595	COG4585	Histidine kinase
EI546_12605	COG0084	hydrolase, TatD family'
EI546_12610	COG0252	asparaginase activity
EI546_12620	COG0811	peptide transport
EI546_12650	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EI546_12655	COG0017	Asparaginyl-tRNA synthetase
EI546_12670	COG0233	cytoplasmic translational termination
EI546_12675	COG0528	UMP kinase activity
EI546_12680	COG1196	nuclear chromosome segregation
EI546_12680	COG0741	lytic transglycosylase activity
EI546_12680	COG0739	heme binding
EI546_12735	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EI546_12740	COG0052	Belongs to the universal ribosomal protein uS2 family
EI546_12745	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EI546_12750	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EI546_12755	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EI546_12790	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EI546_12790	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EI546_12840	COG1446	asparaginase
EI546_12845	COG3537	Alpha-1,2-mannosidase
EI546_12850	COG1408	metallophosphoesterase
EI546_12855	COG3118	belongs to the thioredoxin family
EI546_12860	COG0726	polysaccharide deacetylase
EI546_12880	COG1487	ribonuclease activity
EI546_12895	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EI546_12910	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EI546_12920	COG0189	ligase activity
EI546_12925	COG4067	protein conserved in archaea
EI546_12925	COG0189	ligase activity
EI546_12930	COG0189	ligase activity
EI546_12935	COG1607	acyl-coa hydrolase
EI546_12950	COG0322	excinuclease ABC activity
EI546_12955	COG1752	Esterase of the alpha-beta hydrolase superfamily
EI546_12955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EI546_12965	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EI546_13020	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EI546_13025	COG1960	acyl-CoA dehydrogenase activity
EI546_13050	COG0459	protein refolding
EI546_13055	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EI546_13080	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EI546_13095	COG0740	serine-type endopeptidase activity
EI546_13100	COG3015	lipoprotein NlpE involved in copper resistance
EI546_13120	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EI546_13155	COG1074	ATP-dependent DNA helicase activity
EI546_13165	COG2116	formate transmembrane transporter activity
EI546_13190	COG2824	Alkylphosphonate utilization operon protein PhnA
EI546_13240	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EI546_13245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EI546_13250	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EI546_13265	COG2315	Protein conserved in bacteria
EI546_13270	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EI546_13300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EI546_13310	COG5002	protein histidine kinase activity
EI546_13315	COG0745	RESPONSE REGULATOR receiver
EI546_13350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EI546_13355	COG1690	Belongs to the RtcB family
EI546_13440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EI546_13445	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EI546_13475	COG3177	Filamentation induced by cAMP protein fic
EI546_13480	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EI546_13485	COG1537	nuclear-transcribed mRNA catabolic process, no-go decay
EI546_13515	COG0022	dehydrogenase e1 component
EI546_13515	COG0508	dehydrogenase complex catalyzes the overall conversion of
EI546_13530	COG4585	Histidine kinase
EI546_13550	COG1902	pentaerythritol trinitrate reductase activity
EI546_13555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EI546_13560	COG0517	IMP dehydrogenase activity
EI546_13565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EI546_13575	COG2176	DNA-directed DNA polymerase activity
EI546_13590	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EI546_13630	COG0142	geranyltranstransferase activity
EI546_13635	COG0644	oxidoreductase
EI546_13650	COG1360	Flagellar Motor Protein
EI546_13665	COG0217	transcriptional regulatory protein
EI546_13690	COG1061	Type III restriction enzyme res subunit
EI546_13695	COG0494	nUDIX hydrolase
EI546_13740	COG1840	ABC-type Fe3 transport system, periplasmic component
EI546_13780	COG0668	transmembrane transport
EI546_13785	COG0531	amino acid
EI546_13810	COG0512	Glutamine amidotransferase of anthranilate synthase
EI546_13810	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EI546_13815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EI546_13855	COG0018	arginyl-trna synthetase
EI546_13865	COG0288	reversible hydration of carbon dioxide
EI546_13870	COG0823	Involved in the tonB-independent uptake of proteins
EI546_13880	COG1595	DNA-templated transcription, initiation
EI546_13890	COG0513	Belongs to the DEAD box helicase family
EI546_13930	COG1012	belongs to the aldehyde dehydrogenase family
EI546_13935	COG0823	Involved in the tonB-independent uptake of proteins
EI546_13935	COG1506	peptidase
EI546_13950	COG2076	Multidrug Resistance protein
EI546_13955	COG0667	Aldo Keto reductase
EI546_13960	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EI546_13970	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EI546_13975	COG3339	Conserved Protein
EI546_14005	COG0433	COG0433 Predicted ATPase
EI546_14010	COG0602	queuosine metabolic process
EI546_14020	COG0187	DNA topoisomerase II activity
EI546_14035	COG0463	Glycosyl transferase, family 2
EI546_14050	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EI546_14075	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EI546_14085	COG3385	transposase activity
EI546_14090	COG3189	MarR family transcriptional regulator
EI546_14095	COG3483	tryptophan 2,3-dioxygenase activity
EI546_14100	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EI546_14130	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EI546_14145	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EI546_14150	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EI546_14165	COG2337	Toxic component of a toxin-antitoxin (TA) module
EI546_14170	COG2030	dehydratase
EI546_14170	COG1012	belongs to the aldehyde dehydrogenase family
EI546_14195	COG0716	FMN binding
EI546_14220	COG0508	dehydrogenase complex catalyzes the overall conversion of
EI546_14260	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EI546_14275	COG1160	GTP binding
EI546_14305	COG2364	Membrane
EI546_14340	COG1704	LemA family
EI546_14350	COG0739	heme binding
EI546_14355	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EI546_14390	COG2197	response regulator
EI546_14410	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EI546_14415	COG1765	OsmC-like protein
EI546_14435	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EI546_14450	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EI546_14475	COG1185	polyribonucleotide nucleotidyltransferase activity
EI546_14480	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EI546_14485	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EI546_14500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EI546_14510	COG2226	methyltransferase
EI546_14515	COG0569	domain protein
EI546_14540	COG3239	Fatty acid desaturase
EI546_14545	COG0357	Ribosomal RNA small subunit methyltransferase G
EI546_14570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EI546_14590	COG2967	ApaG domain
EI546_14605	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EI546_14610	COG1805	sodium ion transport
EI546_14615	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EI546_14620	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EI546_14630	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EI546_14645	COG1477	protein flavinylation
EI546_14655	COG2226	methyltransferase
EI546_14680	COG1506	peptidase
EI546_14680	COG0823	Involved in the tonB-independent uptake of proteins
EI546_14690	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EI546_14705	COG3279	Response regulator of the LytR AlgR family
EI546_14710	COG2972	Histidine kinase
EI546_14750	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EI546_14755	COG3530	Putative quorum-sensing-regulated virulence factor
EI546_14770	COG1388	LysM domain
EI546_14770	COG1705	Flagellar rod assembly protein muramidase FlgJ
EI546_14775	COG0519	Catalyzes the synthesis of GMP from XMP
EI546_14775	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EI546_14780	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EI546_14835	COG1216	Glycosyl transferase, family 2
EI546_14835	COG0463	Glycosyl transferase, family 2
EI546_14845	COG1404	Belongs to the peptidase S8 family
EI546_14850	COG2884	Cell division ATP-binding protein ftsE
EI546_14885	COG3920	Histidine kinase
EI546_14905	COG3119	arylsulfatase activity
EI546_14910	COG2015	COG2015, Alkyl sulfatase and related hydrolases
EI546_14920	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EI546_14925	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EI546_14960	COG3876	Protein conserved in bacteria
EI546_14965	COG0577	efflux transmembrane transporter activity
EI546_15005	COG1115	amino acid carrier protein
EI546_15015	COG1960	acyl-CoA dehydrogenase activity
EI546_15035	COG1252	NADH dehydrogenase
EI546_15050	COG3275	phosphorelay sensor kinase activity
EI546_15065	COG3279	Response regulator of the LytR AlgR family
EI546_15095	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EI546_15110	COG0037	tRNA processing
EI546_15115	COG0205	6-phosphofructokinase activity
EI546_15130	COG0606	chelatase, subunit chli
EI546_15135	COG0612	Peptidase, M16
EI546_15140	COG0745	RESPONSE REGULATOR receiver
EI546_15145	COG2205	protein histidine kinase activity
EI546_15150	COG1408	metallophosphoesterase
EI546_15215	COG1519	Transferase
EI546_15215	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EI546_15225	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EI546_15250	COG1764	response to oxidative stress
EI546_15280	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EI546_15290	COG3385	transposase activity
EI546_15300	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EI546_15305	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EI546_15315	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EI546_15320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EI546_15330	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EI546_15335	COG2086	electron transfer activity
EI546_15360	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EI546_15370	COG0489	protein tyrosine kinase activity
EI546_15370	COG3206	protein involved in exopolysaccharide biosynthesis
EI546_15380	COG0095	Lipoate-protein ligase
EI546_15395	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EI546_15420	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
EI546_15425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EI546_15435	COG0534	Mate efflux family protein
EI546_15445	COG0671	phosphoesterase, PA-phosphatase related
EI546_15450	COG0463	Glycosyl transferase, family 2
EI546_15475	COG1764	response to oxidative stress
EI546_15555	COG1132	(ABC) transporter
EI546_15560	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EI546_15565	COG0463	Glycosyl transferase, family 2
EI546_15575	COG0254	rRNA binding
EI546_15600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EI546_15630	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EI546_15660	COG1120	ATPase activity
EI546_15665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EI546_15690	COG1595	DNA-templated transcription, initiation
EI546_15715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EI546_15725	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EI546_15735	COG0438	transferase activity, transferring glycosyl groups
EI546_15745	COG0363	glucosamine-6-phosphate deaminase activity
EI546_15760	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EI546_15765	COG3588	fructose-bisphosphate aldolase
EI546_15785	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EI546_15790	COG0698	ribose 5-phosphate isomerase
EI546_15795	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EI546_15800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EI546_15805	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EI546_15810	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EI546_15815	COG0363	glucosamine-6-phosphate deaminase activity
EI546_15820	COG0166	Belongs to the GPI family
EI546_15835	COG1482	cell wall glycoprotein biosynthetic process
EI546_15845	COG0322	excinuclease ABC activity
EI546_15855	COG3237	CsbD-like
EI546_15860	COG0542	response to heat
EI546_15865	COG3118	belongs to the thioredoxin family
EI546_15880	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EI546_15885	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EI546_15890	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EI546_15895	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EI546_15955	COG0572	uridine kinase
EI546_15965	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EI546_15975	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EI546_15975	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EI546_15990	COG0501	Belongs to the peptidase M48B family
EI546_15995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EI546_16010	COG2195	Cleaves the N-terminal amino acid of tripeptides
EI546_16015	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EI546_16025	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EI546_16030	COG0105	UTP biosynthetic process
EI546_16050	COG0488	(ABC) transporter