locus-tag	class	description
JK629_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JK629_00010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JK629_00040	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JK629_00045	COG0626	cystathionine gamma-synthase activity
JK629_00050	COG1228	amidohydrolase
JK629_00075	COG0488	(ABC) transporter
JK629_00085	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JK629_00110	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JK629_00115	COG1575	Belongs to the MenA family. Type 1 subfamily
JK629_00155	COG0009	L-threonylcarbamoyladenylate synthase
JK629_00175	COG0069	glutamate synthase activity
JK629_00190	COG4585	Histidine kinase
JK629_00210	COG0308	aminopeptidase N
JK629_00215	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JK629_00225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JK629_00235	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JK629_00245	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JK629_00265	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JK629_00275	COG3956	TIGRFAM MazG family protein
JK629_00285	COG0242	peptide deformylase activity
JK629_00290	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JK629_00310	COG1216	Glycosyl transferase, family 2
JK629_00320	COG0463	Glycosyl transferase, family 2
JK629_00330	COG1215	transferase activity, transferring glycosyl groups
JK629_00335	COG0009	L-threonylcarbamoyladenylate synthase
JK629_00345	COG0617	tRNA 3'-terminal CCA addition
JK629_00345	COG0517	IMP dehydrogenase activity
JK629_00345	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JK629_00350	COG1612	heme a metabolic process
JK629_00370	COG0514	ATP-dependent DNA helicase (RecQ)
JK629_00375	COG0517	IMP dehydrogenase activity
JK629_00375	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JK629_00380	COG0805	protein transport
JK629_00390	COG1137	ATPase activity
JK629_00415	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JK629_00420	COG0438	transferase activity, transferring glycosyl groups
JK629_00475	COG0438	transferase activity, transferring glycosyl groups
JK629_00485	COG1215	transferase activity, transferring glycosyl groups
JK629_00500	COG0438	transferase activity, transferring glycosyl groups
JK629_00505	COG0438	transferase activity, transferring glycosyl groups
JK629_00515	COG0438	transferase activity, transferring glycosyl groups
JK629_00540	COG1216	Glycosyl transferase, family 2
JK629_00540	COG0463	Glycosyl transferase, family 2
JK629_00610	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JK629_00655	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JK629_00660	COG3206	protein involved in exopolysaccharide biosynthesis
JK629_00660	COG0489	protein tyrosine kinase activity
JK629_00680	COG0488	(ABC) transporter
JK629_00690	COG1136	(ABC) transporter
JK629_00710	COG0653	protein targeting
JK629_00745	COG1764	response to oxidative stress
JK629_00765	COG1368	sulfuric ester hydrolase activity
JK629_00775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JK629_00780	COG0463	Glycosyl transferase, family 2
JK629_00795	COG0671	phosphoesterase, PA-phosphatase related
JK629_00805	COG0534	Mate efflux family protein
JK629_00880	COG2326	polyphosphate kinase activity
JK629_00885	COG2204	response regulator
JK629_00895	COG1668	transmembrane transport
JK629_00900	COG4152	abc transporter atp-binding protein
JK629_00905	COG0484	heat shock protein binding
JK629_00910	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JK629_00925	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
JK629_00925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JK629_00935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JK629_00960	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JK629_00985	COG1522	sequence-specific DNA binding
JK629_00995	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JK629_00995	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JK629_00995	COG1703	isobutyryl-CoA mutase activity
JK629_01015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JK629_01020	COG0284	orotidine-5'-phosphate decarboxylase activity
JK629_01025	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JK629_01035	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JK629_01040	COG0823	Involved in the tonB-independent uptake of proteins
JK629_01045	COG1462	curli production assembly transport component CsgG
JK629_01085	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JK629_01105	COG2264	protein methyltransferase activity
JK629_01110	COG0149	triose-phosphate isomerase activity
JK629_01115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JK629_01120	COG0601	transmembrane transport
JK629_01135	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JK629_01140	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JK629_01145	COG1132	(ABC) transporter
JK629_01150	COG0101	tRNA pseudouridine synthase activity
JK629_01175	COG0494	nUDIX hydrolase
JK629_01180	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JK629_01190	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
JK629_01190	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
JK629_01195	COG0799	negative regulation of ribosome biogenesis
JK629_01200	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JK629_01210	COG4589	Belongs to the CDS family
JK629_01215	COG0688	phosphatidylethanolamine metabolic process
JK629_01230	COG0525	valine-tRNA ligase activity
JK629_01245	COG0436	Aminotransferase
JK629_01250	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JK629_01265	COG1216	Glycosyl transferase, family 2
JK629_01270	COG1595	DNA-templated transcription, initiation
JK629_01275	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JK629_01280	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JK629_01285	COG2205	protein histidine kinase activity
JK629_01285	COG0784	Response regulator, receiver
JK629_01285	COG2198	Histidine kinase
JK629_01290	COG1663	tetraacyldisaccharide 4'-kinase activity
JK629_01295	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JK629_01305	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JK629_01345	COG3844	kynureninase activity
JK629_01350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JK629_01365	COG1028	Short-chain dehydrogenase reductase Sdr
JK629_01380	COG3104	oligopeptide transport
JK629_01385	COG4122	O-methyltransferase activity
JK629_01390	COG0671	phosphoesterase, PA-phosphatase related
JK629_01395	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JK629_01420	COG3340	Belongs to the peptidase S51 family
JK629_01435	COG1876	peptidase activity
JK629_01440	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JK629_01460	COG2226	methyltransferase
JK629_01470	COG1477	protein flavinylation
JK629_01485	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JK629_01495	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JK629_01500	COG1805	sodium ion transport
JK629_01520	COG2967	ApaG domain
JK629_01530	COG1012	belongs to the aldehyde dehydrogenase family
JK629_01540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JK629_01565	COG0357	Ribosomal RNA small subunit methyltransferase G
JK629_01570	COG3239	Fatty acid desaturase
JK629_01575	COG0436	Aminotransferase
JK629_01585	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JK629_01595	COG0569	domain protein
JK629_01600	COG2226	methyltransferase
JK629_01610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JK629_01620	COG0191	fructose-bisphosphate aldolase activity
JK629_01625	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JK629_01635	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JK629_01640	COG1185	polyribonucleotide nucleotidyltransferase activity
JK629_01665	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JK629_01675	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JK629_01680	COG0492	ferredoxin-NADP+ reductase activity
JK629_01685	COG3228	Belongs to the MtfA family
JK629_01695	COG1629	transport
JK629_01715	COG4206	TonB-dependent receptor
JK629_01715	COG1629	transport
JK629_01720	COG2217	Heavy metal translocating P-type atpase
JK629_01725	COG0701	Predicted permease
JK629_01735	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JK629_01780	COG0138	bifunctional purine biosynthesis protein purh
JK629_01785	COG1077	Cell shape determining protein MreB Mrl
JK629_01800	COG0768	penicillin binding
JK629_01805	COG0772	Belongs to the SEDS family
JK629_01820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JK629_01830	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JK629_01840	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JK629_01850	COG0268	Binds directly to 16S ribosomal RNA
JK629_01860	COG0442	prolyl-tRNA aminoacylation
JK629_01875	COG0302	gtp cyclohydrolase
JK629_01880	COG0215	cysteine-tRNA ligase activity
JK629_01885	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JK629_01890	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JK629_01900	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JK629_01940	COG0187	DNA topoisomerase II activity
JK629_01950	COG0602	queuosine metabolic process
JK629_01960	COG0433	COG0433 Predicted ATPase
JK629_01995	COG3339	Conserved Protein
JK629_02000	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JK629_02010	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JK629_02020	COG3279	Response regulator of the LytR AlgR family
JK629_02060	COG0798	PFAM Bile acid sodium symporter
JK629_02075	COG0513	Belongs to the DEAD box helicase family
JK629_02085	COG0745	RESPONSE REGULATOR receiver
JK629_02100	COG1064	alcohol dehydrogenase
JK629_02140	COG0288	reversible hydration of carbon dioxide
JK629_02150	COG0018	arginyl-trna synthetase
JK629_02155	COG2095	MarC family integral membrane protein
JK629_02180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JK629_02185	COG1477	protein flavinylation
JK629_02205	COG1054	Belongs to the UPF0176 family
JK629_02210	COG1054	Belongs to the UPF0176 family
JK629_02220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JK629_02225	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JK629_02230	COG0512	Glutamine amidotransferase of anthranilate synthase
JK629_02235	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JK629_02240	COG0134	indole-3-glycerol-phosphate synthase activity
JK629_02245	COG0135	phosphoribosylanthranilate isomerase activity
JK629_02250	COG0133	tryptophan synthase activity
JK629_02255	COG0159	tryptophan synthase activity
JK629_02280	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JK629_02305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JK629_02315	COG3189	MarR family transcriptional regulator
JK629_02350	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JK629_02355	COG2226	methyltransferase
JK629_02370	COG0463	Glycosyl transferase, family 2
JK629_02385	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JK629_02400	COG1215	transferase activity, transferring glycosyl groups
JK629_02415	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JK629_02435	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JK629_02445	COG0563	adenylate kinase activity
JK629_02465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JK629_02470	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JK629_02480	COG4221	oxidoreductase activity
JK629_02515	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JK629_02530	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JK629_02535	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JK629_02545	COG0339	signal peptide processing
JK629_02570	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JK629_02570	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JK629_02575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JK629_02590	COG1785	Belongs to the alkaline phosphatase family
JK629_02595	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JK629_02625	COG1028	Short-chain dehydrogenase reductase Sdr
JK629_02630	COG0508	dehydrogenase complex catalyzes the overall conversion of
JK629_02635	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JK629_02655	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JK629_02660	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JK629_02685	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JK629_02715	COG0848	biopolymer transport protein
JK629_02720	COG0811	peptide transport
JK629_02735	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JK629_02740	COG1960	acyl-CoA dehydrogenase activity
JK629_02755	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JK629_02775	COG2205	protein histidine kinase activity
JK629_02775	COG0745	RESPONSE REGULATOR receiver
JK629_02775	COG3292	Two component regulator propeller
JK629_02790	COG0321	lipoyl(octanoyl) transferase activity
JK629_02815	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JK629_02835	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JK629_02840	COG1388	LysM domain
JK629_02840	COG0791	NLP P60 protein
JK629_02845	COG2515	1-aminocyclopropane-1-carboxylate deaminase
JK629_02855	COG4585	Histidine kinase
JK629_02880	COG0508	dehydrogenase complex catalyzes the overall conversion of
JK629_02880	COG0022	dehydrogenase e1 component
JK629_02890	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JK629_02900	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JK629_02910	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JK629_02925	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JK629_02930	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
JK629_02945	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JK629_02955	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JK629_02965	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JK629_02975	COG1519	Transferase
JK629_02975	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JK629_03030	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JK629_03080	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JK629_03085	COG0628	permease
JK629_03105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JK629_03130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JK629_03135	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JK629_03145	COG0463	Glycosyl transferase, family 2
JK629_03205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JK629_03210	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JK629_03220	COG2204	response regulator
JK629_03225	COG4191	Histidine kinase
JK629_03265	COG0740	serine-type endopeptidase activity
JK629_03290	COG0228	four-way junction DNA binding
JK629_03295	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JK629_03300	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JK629_03335	COG0633	Ferredoxin
JK629_03340	COG0492	ferredoxin-NADP+ reductase activity
JK629_03350	COG0489	protein tyrosine kinase activity
JK629_03355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JK629_03365	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JK629_03370	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JK629_03375	COG5002	protein histidine kinase activity
JK629_03380	COG0745	RESPONSE REGULATOR receiver
JK629_03395	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JK629_03415	COG0463	Glycosyl transferase, family 2
JK629_03430	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JK629_03435	COG2363	Small membrane protein
JK629_03445	COG2738	Putative neutral zinc metallopeptidase
JK629_03450	COG0495	leucyl-tRNA aminoacylation
JK629_03460	COG2177	Part of the ABC transporter FtsEX involved in
JK629_03470	COG1968	undecaprenyl-diphosphatase activity
JK629_03475	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JK629_03485	COG0519	Catalyzes the synthesis of GMP from XMP
JK629_03505	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
JK629_03515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JK629_03535	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JK629_03550	COG0784	Response regulator, receiver
JK629_03550	COG2205	protein histidine kinase activity
JK629_03565	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JK629_03590	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JK629_03600	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JK629_03610	COG0436	Aminotransferase
JK629_03615	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
JK629_03635	COG1040	competence protein
JK629_03645	COG0423	glycine-tRNA ligase activity
JK629_03660	COG0708	Exodeoxyribonuclease III
JK629_03665	COG0667	Aldo Keto reductase
JK629_03670	COG1960	acyl-CoA dehydrogenase activity
JK629_03675	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JK629_03680	COG4585	Histidine kinase
JK629_03700	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JK629_03705	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JK629_03710	COG0297	glycogen (starch) synthase activity
JK629_03720	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JK629_03765	COG1530	ribonuclease E activity
JK629_03770	COG0776	regulation of translation
JK629_03780	COG0629	single-stranded DNA binding
JK629_03800	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JK629_03800	COG3743	rRNA binding
JK629_03805	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JK629_03830	COG1053	succinate dehydrogenase
JK629_03865	COG0006	proline dipeptidase activity
JK629_03870	COG2267	carboxylic ester hydrolase activity
JK629_03880	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JK629_03900	COG1858	cytochrome C peroxidase
JK629_03905	COG0316	Belongs to the HesB IscA family
JK629_03910	COG0719	Fe-S assembly protein
JK629_03920	COG0396	ATPase activity
JK629_03925	COG0719	Fe-S assembly protein
JK629_03930	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JK629_03940	COG2166	iron-sulfur cluster assembly
JK629_03945	COG2151	metal-sulfur cluster biosynthetic enzyme
JK629_03960	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JK629_04000	COG4771	TonB-dependent receptor
JK629_04015	COG3185	4-Hydroxyphenylpyruvate dioxygenase
JK629_04020	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
JK629_04030	COG0322	excinuclease ABC activity
JK629_04040	COG4206	TonB-dependent receptor
JK629_04045	COG0189	ligase activity
JK629_04050	COG0189	ligase activity
JK629_04050	COG4067	protein conserved in archaea
JK629_04055	COG0189	ligase activity
JK629_04065	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JK629_04080	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JK629_04090	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JK629_04145	COG2855	membrane
JK629_04150	COG0668	transmembrane transport
JK629_04205	COG1012	belongs to the aldehyde dehydrogenase family
JK629_04210	COG1247	-acetyltransferase
JK629_04215	COG1381	Involved in DNA repair and RecF pathway recombination
JK629_04225	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JK629_04235	COG1054	Belongs to the UPF0176 family
JK629_04240	COG1774	PSP1 C-terminal conserved region
JK629_04250	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JK629_04255	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JK629_04265	COG4172	Belongs to the ABC transporter superfamily
JK629_04295	COG1253	flavin adenine dinucleotide binding
JK629_04310	COG0113	porphobilinogen synthase activity
JK629_04325	COG0408	coproporphyrinogen oxidase activity
JK629_04330	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
JK629_04345	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JK629_04355	COG0569	domain protein
JK629_04360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JK629_04365	COG0181	hydroxymethylbilane synthase activity
JK629_04370	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JK629_04385	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JK629_04400	COG1981	membrane
JK629_04405	COG5000	phosphorelay sensor kinase activity
JK629_04410	COG1024	Enoyl-CoA hydratase
JK629_04415	COG0071	Belongs to the small heat shock protein (HSP20) family
JK629_04430	COG1418	mRNA catabolic process
JK629_04450	COG0484	heat shock protein binding
JK629_04455	COG1321	iron dependent repressor
JK629_04455	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JK629_04460	COG0803	Belongs to the bacterial solute-binding protein 9 family
JK629_04465	COG1121	(ABC) transporter
JK629_04470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JK629_04475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JK629_04495	COG1999	signal sequence binding
JK629_04540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JK629_04550	COG3590	peptidase
JK629_04565	COG0516	GMP reductase activity
JK629_04565	COG0517	IMP dehydrogenase activity
JK629_04575	COG0629	single-stranded DNA binding
JK629_04590	COG2183	response to ionizing radiation
JK629_04600	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JK629_04600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JK629_04605	COG1619	proteins homologs of microcin C7 resistance protein MccF
JK629_04610	COG0792	nuclease activity
JK629_04620	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JK629_04640	COG1201	RNA secondary structure unwinding
JK629_04645	COG1793	dna ligase
JK629_04660	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
JK629_04670	COG0527	aspartate kinase activity
JK629_04700	COG0346	lactoylglutathione lyase activity
JK629_04705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JK629_04720	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JK629_04725	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JK629_04730	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JK629_04735	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JK629_04740	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JK629_04745	COG0356	it plays a direct role in the translocation of protons across the membrane
JK629_04805	COG0151	Belongs to the GarS family
JK629_04830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JK629_04835	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JK629_04870	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JK629_04875	COG2089	acid synthase
JK629_04920	COG1388	LysM domain
JK629_04920	COG4942	peptidase
JK629_04925	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JK629_04935	COG0791	NLP P60 protein
JK629_04935	COG1388	LysM domain
JK629_04940	COG0126	phosphoglycerate kinase activity
JK629_04955	COG0445	tRNA wobble uridine modification
JK629_04960	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JK629_04970	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JK629_05030	COG0557	exoribonuclease II activity
JK629_05040	COG0698	ribose 5-phosphate isomerase
JK629_05050	COG2153	protein acetylation
JK629_05070	COG0793	Belongs to the peptidase S41A family
JK629_05080	COG0594	ribonuclease P activity
JK629_05095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JK629_05100	COG3263	regulation of cellular component size
JK629_05110	COG0481	GTPase activity
JK629_05125	COG4591	ABC-type transport system involved in lipoprotein release permease component
JK629_05130	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JK629_05150	COG0307	riboflavin synthase, alpha
JK629_05155	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JK629_05165	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JK629_05170	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JK629_05175	COG0511	ligase activity, forming carbon-carbon bonds
JK629_05180	COG0439	Biotin carboxylase
JK629_05190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JK629_05205	COG1289	transmembrane transporter activity
JK629_05210	COG2130	NADP-dependent
JK629_05215	COG3842	ATPase activity
JK629_05230	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JK629_05245	COG0659	secondary active sulfate transmembrane transporter activity
JK629_05255	COG0659	secondary active sulfate transmembrane transporter activity
JK629_05280	COG2304	oxidoreductase activity
JK629_05285	COG2304	oxidoreductase activity
JK629_05300	COG0714	Associated with various cellular activities
JK629_05320	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JK629_05330	COG1012	belongs to the aldehyde dehydrogenase family
JK629_05345	COG1446	asparaginase
JK629_05360	COG4953	penicillin-binding protein 1C
JK629_05370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JK629_05390	COG2954	triphosphatase activity
JK629_05400	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JK629_05410	COG0469	pyruvate kinase activity
JK629_05420	COG0571	ribonuclease III activity
JK629_05425	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JK629_05430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JK629_05440	COG0328	RNA-DNA hybrid ribonuclease activity
JK629_05440	COG3341	Caulimovirus viroplasmin
JK629_05450	COG1105	Belongs to the carbohydrate kinase PfkB family
JK629_05460	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JK629_05465	COG1074	ATP-dependent DNA helicase activity
JK629_05470	COG0156	8-amino-7-oxononanoate synthase activity
JK629_05475	COG2885	chlorophyll binding
JK629_05510	COG0720	synthase
JK629_05520	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JK629_05520	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JK629_05540	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JK629_05555	COG1435	thymidine kinase activity
JK629_05560	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JK629_05570	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JK629_05580	COG1505	serine-type exopeptidase activity
JK629_05590	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JK629_05595	COG0194	GDP metabolic process
JK629_05600	COG1561	YicC-like family, N-terminal region
JK629_05605	COG0429	hydrolase of the alpha beta-hydrolase fold
JK629_05615	COG0697	spore germination
JK629_05630	COG0626	cystathionine gamma-synthase activity
JK629_05650	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JK629_05670	COG0180	Tryptophanyl-tRNA synthetase
JK629_05675	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JK629_05675	COG0758	DNA mediated transformation
JK629_05685	COG1607	acyl-coa hydrolase
JK629_05710	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JK629_05715	COG0756	dUTP diphosphatase activity
JK629_05730	COG2239	Acts as a magnesium transporter
JK629_05735	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JK629_05765	COG2095	MarC family integral membrane protein
JK629_05775	COG0793	Belongs to the peptidase S41A family
JK629_05850	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JK629_05855	COG1061	Type III restriction enzyme res subunit
JK629_05860	COG1002	Type II restriction enzyme, methylase subunits
JK629_05880	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JK629_05885	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JK629_05890	COG0193	aminoacyl-tRNA hydrolase activity
JK629_05895	COG0196	riboflavin kinase activity
JK629_05905	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JK629_05915	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JK629_05915	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JK629_05960	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JK629_05970	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JK629_05980	COG1278	Cold shock
JK629_05990	COG0038	chloride channel
JK629_05995	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JK629_06030	COG0508	dehydrogenase complex catalyzes the overall conversion of
JK629_06040	COG4585	Histidine kinase
JK629_06050	COG0084	hydrolase, TatD family'
JK629_06055	COG0252	asparaginase activity
JK629_06065	COG0811	peptide transport
JK629_06095	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JK629_06100	COG0017	Asparaginyl-tRNA synthetase
JK629_06125	COG0233	cytoplasmic translational termination
JK629_06130	COG0528	UMP kinase activity
JK629_06140	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JK629_06145	COG0052	Belongs to the universal ribosomal protein uS2 family
JK629_06150	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JK629_06155	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JK629_06165	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JK629_06165	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JK629_06175	COG4242	Belongs to the peptidase S51 family
JK629_06180	COG0189	ligase activity
JK629_06180	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JK629_06190	COG3118	belongs to the thioredoxin family
JK629_06225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JK629_06240	COG1028	Short-chain dehydrogenase reductase Sdr
JK629_06245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JK629_06250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JK629_06265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JK629_06270	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JK629_06290	COG1131	(ABC) transporter
JK629_06305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JK629_06320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JK629_06350	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JK629_06385	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
JK629_06395	COG0589	response to stress
JK629_06400	COG0779	Required for maturation of 30S ribosomal subunits
JK629_06405	COG0195	Participates in both transcription termination and antitermination
JK629_06410	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JK629_06420	COG4654	Cytochrome c, class I
JK629_06425	COG0437	4 iron, 4 sulfur cluster binding
JK629_06430	COG0052	Belongs to the universal ribosomal protein uS2 family
JK629_06430	COG3743	rRNA binding
JK629_06450	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JK629_06455	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JK629_06460	COG2255	four-way junction helicase activity
JK629_06470	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JK629_06480	COG0632	four-way junction helicase activity
JK629_06490	COG0509	glycine decarboxylation via glycine cleavage system
JK629_06520	COG0109	protoheme IX farnesyltransferase activity
JK629_06525	COG1845	cytochrome c oxidase, subunit III
JK629_06530	COG1845	cytochrome c oxidase, subunit III
JK629_06545	COG1999	signal sequence binding
JK629_06550	COG2322	membrane
JK629_06560	COG1136	(ABC) transporter
JK629_06565	COG0577	efflux transmembrane transporter activity
JK629_06565	COG1136	(ABC) transporter
JK629_06570	COG0577	efflux transmembrane transporter activity
JK629_06570	COG1136	(ABC) transporter
JK629_06580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JK629_06605	COG0668	transmembrane transport
JK629_06610	COG1331	Highly conserved protein containing a thioredoxin domain
JK629_06645	COG3275	phosphorelay sensor kinase activity
JK629_06650	COG3279	Response regulator of the LytR AlgR family
JK629_06655	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JK629_06660	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JK629_06680	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JK629_06690	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JK629_06700	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
JK629_06705	COG0596	Alpha beta hydrolase
JK629_06720	COG1950	PFAM Membrane protein of
JK629_06725	COG0544	peptidyl-prolyl cis-trans isomerase activity
JK629_06735	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JK629_06755	COG1428	Deoxynucleoside kinase
JK629_06760	COG1187	pseudouridine synthase activity
JK629_06770	COG0010	Belongs to the arginase family
JK629_06775	COG1899	peptidyl-lysine modification to peptidyl-hypusine
JK629_06780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JK629_06780	COG3153	acetyltransferase
JK629_06800	COG0459	protein refolding
JK629_06805	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JK629_06830	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JK629_06850	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JK629_06880	COG0488	(ABC) transporter
JK629_06885	COG1752	Esterase of the alpha-beta hydrolase superfamily
JK629_06925	COG2824	Alkylphosphonate utilization operon protein PhnA
JK629_06960	COG1475	DNA binding
JK629_07000	COG0629	single-stranded DNA binding
JK629_07005	COG0629	single-stranded DNA binding
JK629_07035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JK629_07115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JK629_07150	COG2217	Heavy metal translocating P-type atpase
JK629_07165	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JK629_07170	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JK629_07175	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
JK629_07195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JK629_07200	COG3174	membrane
JK629_07205	COG0205	6-phosphofructokinase activity
JK629_07215	COG1830	Aldolase
JK629_07305	COG2132	Multicopper oxidase
JK629_07325	COG0701	Predicted permease
JK629_07365	COG0347	Belongs to the P(II) protein family
JK629_07380	COG2217	Heavy metal translocating P-type atpase
JK629_07385	COG2217	Heavy metal translocating P-type atpase
JK629_07415	COG0076	glutamate decarboxylase activity
JK629_07420	COG2081	HI0933 family
JK629_07450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JK629_07455	COG4558	Periplasmic binding protein
JK629_07470	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JK629_07480	COG1902	pentaerythritol trinitrate reductase activity
JK629_07485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JK629_07495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JK629_07500	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JK629_07500	COG1333	cytochrome c biogenesis protein
JK629_07500	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JK629_07500	COG1333	cytochrome c biogenesis protein
JK629_07525	COG0492	ferredoxin-NADP+ reductase activity
JK629_07595	COG1629	transport
JK629_07620	COG0084	hydrolase, TatD family'
JK629_07665	COG1309	transcriptional regulator
JK629_07675	COG0697	spore germination
JK629_07690	COG2318	DinB family
JK629_07695	COG1028	Short-chain dehydrogenase reductase Sdr
JK629_07715	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JK629_07730	COG3275	phosphorelay sensor kinase activity
JK629_07740	COG0006	proline dipeptidase activity
JK629_07780	COG3609	addiction module antidote protein, CC2985 family
JK629_07815	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JK629_07850	COG0778	Nitroreductase
JK629_07890	COG0456	acetyltransferase
JK629_07905	COG1131	(ABC) transporter
JK629_07925	COG3279	Response regulator of the LytR AlgR family
JK629_07930	COG3275	phosphorelay sensor kinase activity
JK629_07950	COG4251	negative regulation of phosphorylation
JK629_07955	COG2201	protein-glutamate methylesterase activity
JK629_07975	COG2169	Transcriptional regulator
JK629_07990	COG2378	regulation of single-species biofilm formation
JK629_07995	COG0534	Mate efflux family protein
JK629_08000	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JK629_08005	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
JK629_08010	COG3174	membrane
JK629_08020	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JK629_08025	COG1428	Deoxynucleoside kinase
JK629_08060	COG3186	Phenylalanine-4-hydroxylase
JK629_08070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JK629_08075	COG3396	Phenylacetate-CoA oxygenase
JK629_08085	COG3460	Phenylacetate-CoA oxygenase
JK629_08095	COG3396	Phenylacetate-CoA oxygenase
JK629_08100	COG2151	metal-sulfur cluster biosynthetic enzyme
JK629_08105	COG1024	Enoyl-CoA hydratase
JK629_08110	COG1250	3-hydroxyacyl-CoA dehydrogenase
JK629_08125	COG2321	neutral zinc metallopeptidase
JK629_08130	COG0183	Belongs to the thiolase family
JK629_08135	COG1012	belongs to the aldehyde dehydrogenase family
JK629_08135	COG2030	dehydratase
JK629_08155	COG0508	dehydrogenase complex catalyzes the overall conversion of
JK629_08160	COG0022	dehydrogenase e1 component
JK629_08180	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JK629_08190	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JK629_08200	COG1160	GTP binding
JK629_08220	COG1704	LemA family
JK629_08235	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JK629_08265	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JK629_08275	COG0527	aspartate kinase activity
JK629_08275	COG0460	homoserine dehydrogenase
JK629_08285	COG0646	methionine synthase
JK629_08285	COG1410	methionine synthase
JK629_08290	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JK629_08300	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JK629_08330	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JK629_08340	COG1162	GTPase activity
JK629_08345	COG1490	D-aminoacyl-tRNA deacylase activity
JK629_08360	COG1694	Mazg nucleotide pyrophosphohydrolase
JK629_08375	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JK629_08385	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JK629_08390	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JK629_08415	COG0358	DNA primase activity
JK629_08420	COG2197	response regulator
JK629_08425	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JK629_08440	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JK629_08450	COG2001	Belongs to the MraZ family
JK629_08455	COG0275	rRNA processing
JK629_08465	COG0768	penicillin binding
JK629_08470	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JK629_08475	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JK629_08480	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JK629_08485	COG0772	Belongs to the SEDS family
JK629_08490	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JK629_08495	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JK629_08510	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JK629_08515	COG1610	YqeY-like protein
JK629_08535	COG2003	Belongs to the UPF0758 family
JK629_08545	COG1011	Hydrolase
JK629_08565	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JK629_08575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JK629_08590	COG1629	transport
JK629_08600	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JK629_08605	COG0049	tRNA binding
JK629_08610	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JK629_08615	COG0051	transcription antitermination factor activity, RNA binding
JK629_08620	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JK629_08625	COG0088	Forms part of the polypeptide exit tunnel
JK629_08630	COG0089	rRNA binding
JK629_08635	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JK629_08640	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JK629_08645	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JK629_08650	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JK629_08655	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JK629_08660	COG0255	Belongs to the universal ribosomal protein uL29 family
JK629_08665	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JK629_08670	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JK629_08675	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JK629_08680	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JK629_08685	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JK629_08690	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JK629_08695	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JK629_08705	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JK629_08710	COG1841	ribosomal large subunit assembly
JK629_08715	COG0200	Binds to the 23S rRNA
JK629_08720	COG0201	protein transport
JK629_08725	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JK629_08730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JK629_08735	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JK629_08740	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JK629_08745	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JK629_08750	COG0202	RNA polymerase activity
JK629_08755	COG0203	ribosomal protein L17
JK629_08760	COG0505	Belongs to the CarA family
JK629_08765	COG0148	phosphopyruvate hydratase activity
JK629_08785	COG3104	oligopeptide transport
JK629_08800	COG0658	competence protein
JK629_08800	COG2333	competence protein COMEC
JK629_08805	COG0791	NLP P60 protein
JK629_08810	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JK629_08815	COG1181	Belongs to the D-alanine--D-alanine ligase family
JK629_08825	COG0564	pseudouridine synthase activity
JK629_08835	COG3401	FG-GAP repeat protein
JK629_08845	COG3591	Belongs to the peptidase S1B family
JK629_08850	COG2354	Protein conserved in bacteria
JK629_08875	COG0488	(ABC) transporter
JK629_08905	COG3263	regulation of cellular component size
JK629_08925	COG3022	response to hydroperoxide
JK629_08940	COG0339	signal peptide processing
JK629_08950	COG4717	serine-type aminopeptidase activity
JK629_09000	COG1595	DNA-templated transcription, initiation
JK629_09015	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
JK629_09040	COG4095	Psort location CytoplasmicMembrane, score
JK629_09050	COG3685	Protein conserved in bacteria
JK629_09095	COG0300	oxidoreductase activity
JK629_09130	COG2949	membrane
JK629_09135	COG4452	Inner membrane protein CreD
JK629_09155	COG2877	3-deoxy-8-phosphooctulonate synthase activity
JK629_09160	COG1217	gtp-binding protein TYPA
JK629_09195	COG0463	Glycosyl transferase, family 2
JK629_09240	COG0438	transferase activity, transferring glycosyl groups
JK629_09250	COG1216	Glycosyl transferase, family 2
JK629_09250	COG0463	Glycosyl transferase, family 2
JK629_09270	COG2884	Cell division ATP-binding protein ftsE
JK629_09280	COG1943	Transposase
JK629_09295	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JK629_09305	COG3876	Protein conserved in bacteria
JK629_09310	COG0577	efflux transmembrane transporter activity
JK629_09330	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JK629_09335	COG1115	amino acid carrier protein
JK629_09340	COG1555	photosystem II stabilization
JK629_09340	COG1596	polysaccharide export
JK629_09345	COG1960	acyl-CoA dehydrogenase activity
JK629_09355	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JK629_09360	COG4974	Belongs to the 'phage' integrase family
JK629_09365	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JK629_09400	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JK629_09410	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JK629_09415	COG0081	regulation of translation
JK629_09420	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JK629_09425	COG0222	ribosome binding
JK629_09430	COG0085	RNA polymerase activity
JK629_09435	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JK629_09445	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JK629_09460	COG2885	chlorophyll binding
JK629_09465	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
JK629_09475	COG1482	cell wall glycoprotein biosynthetic process
JK629_09495	COG0596	Alpha beta hydrolase
JK629_09510	COG4935	Belongs to the peptidase S8 family
JK629_09510	COG1404	Belongs to the peptidase S8 family
JK629_09515	COG0326	Molecular chaperone. Has ATPase activity
JK629_09525	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JK629_09530	COG1506	peptidase
JK629_09530	COG0823	Involved in the tonB-independent uptake of proteins
JK629_09535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JK629_09550	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JK629_09560	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JK629_09570	COG0508	dehydrogenase complex catalyzes the overall conversion of
JK629_09575	COG5002	protein histidine kinase activity
JK629_09575	COG2176	DNA-directed DNA polymerase activity
JK629_09580	COG0179	Fumarylacetoacetate (FAA) hydrolase
JK629_09590	COG1546	Belongs to the CinA family
JK629_09590	COG1058	Belongs to the CinA family
JK629_09595	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JK629_09600	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JK629_09610	COG0552	protein localization to endoplasmic reticulum
JK629_09615	COG1506	peptidase
JK629_09615	COG0823	Involved in the tonB-independent uptake of proteins
JK629_09620	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JK629_09655	COG4974	Belongs to the 'phage' integrase family
JK629_09685	COG0038	chloride channel
JK629_09735	COG0556	nucleotide-excision repair
JK629_09750	COG1187	pseudouridine synthase activity
JK629_09755	COG0071	Belongs to the small heat shock protein (HSP20) family
JK629_09770	COG0045	succinate-CoA ligase (ADP-forming) activity
JK629_09775	COG0019	diaminopimelate decarboxylase activity
JK629_09795	COG1404	Belongs to the peptidase S8 family
JK629_09800	COG0482	sulfurtransferase activity
JK629_09810	COG0706	membrane insertase activity
JK629_09815	COG0504	CTP synthase activity
JK629_09825	COG3530	Putative quorum-sensing-regulated virulence factor
JK629_09840	COG1388	LysM domain
JK629_09840	COG3942	CHAP domain
JK629_09845	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JK629_09845	COG0519	Catalyzes the synthesis of GMP from XMP
JK629_09850	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JK629_09870	COG1704	LemA family
JK629_09880	COG2304	oxidoreductase activity
JK629_09895	COG1131	(ABC) transporter
JK629_09910	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JK629_09915	COG2318	DinB family
JK629_09930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JK629_09950	COG0659	secondary active sulfate transmembrane transporter activity
JK629_09965	COG1132	(ABC) transporter
JK629_09975	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JK629_09985	COG1862	Preprotein translocase
JK629_09990	COG2195	Cleaves the N-terminal amino acid of tripeptides
JK629_09995	COG0167	dihydroorotate dehydrogenase activity
JK629_10000	COG1280	lysine exporter protein (LysE YggA)
JK629_10005	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JK629_10010	COG0737	Belongs to the 5'-nucleotidase family
JK629_10040	COG0516	GMP reductase activity
JK629_10040	COG0517	IMP dehydrogenase activity
JK629_10055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JK629_10065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JK629_10070	COG0714	Associated with various cellular activities
JK629_10080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JK629_10125	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JK629_10130	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JK629_10145	COG3958	Transketolase
JK629_10150	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JK629_10155	COG0343	queuine tRNA-ribosyltransferase activity
JK629_10170	COG0825	malonyl-CoA metabolic process
JK629_10175	COG0305	Participates in initiation and elongation during chromosome replication
JK629_10185	COG2885	chlorophyll binding
JK629_10190	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JK629_10195	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JK629_10200	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JK629_10205	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JK629_10235	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JK629_10255	COG0335	large ribosomal subunit rRNA binding
JK629_10260	COG0336	Belongs to the RNA methyltransferase TrmD family
JK629_10300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JK629_10305	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JK629_10315	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JK629_10320	COG2234	aminopeptidase activity
JK629_10330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JK629_10330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JK629_10345	COG0562	UDP-galactopyranose mutase
JK629_10370	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JK629_10385	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JK629_10405	COG1012	belongs to the aldehyde dehydrogenase family
JK629_10425	COG1028	Short-chain dehydrogenase reductase Sdr
JK629_10430	COG1192	Involved in chromosome partitioning
JK629_10435	COG1475	DNA binding
JK629_10445	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JK629_10455	COG2133	pyrroloquinoline quinone binding
JK629_10465	COG0439	Biotin carboxylase
JK629_10470	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JK629_10475	COG0730	response to heat
JK629_10500	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JK629_10505	COG1127	ABC transporter
JK629_10530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JK629_10535	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JK629_10565	COG2988	succinylglutamate desuccinylase activity
JK629_10570	COG0189	ligase activity
JK629_10605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JK629_10630	COG0589	response to stress
JK629_10635	COG0813	purine-nucleoside phosphorylase activity
JK629_10640	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JK629_10660	COG2205	protein histidine kinase activity
JK629_10665	COG0745	RESPONSE REGULATOR receiver
JK629_10700	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
JK629_10740	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
JK629_10745	COG4263	nitrous-oxide reductase activity
JK629_10765	COG1131	(ABC) transporter
JK629_10790	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JK629_10795	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JK629_10805	COG0427	acetyl-CoA hydrolase
JK629_10830	COG2217	Heavy metal translocating P-type atpase
JK629_10850	COG2010	Cytochrome c
JK629_10855	COG0348	domain, Protein
JK629_10885	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JK629_10900	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JK629_10910	COG0492	ferredoxin-NADP+ reductase activity
JK629_10965	COG0714	Associated with various cellular activities
JK629_11000	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JK629_11035	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JK629_11050	COG3655	Transcriptional regulator
JK629_11065	COG3275	phosphorelay sensor kinase activity
JK629_11085	COG3279	Response regulator of the LytR AlgR family
JK629_11145	COG0037	tRNA processing
JK629_11150	COG0205	6-phosphofructokinase activity
JK629_11165	COG0166	Belongs to the GPI family
JK629_11170	COG0606	chelatase, subunit chli
JK629_11175	COG0612	Peptidase, M16
JK629_11205	COG4585	Histidine kinase
JK629_11210	COG2197	response regulator
JK629_11215	COG0564	pseudouridine synthase activity
JK629_11220	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JK629_11230	COG1760	l-serine dehydratase
JK629_11245	COG1028	Short-chain dehydrogenase reductase Sdr
JK629_11255	COG0443	Heat shock 70 kDa protein
JK629_11275	COG2050	protein possibly involved in aromatic compounds catabolism
JK629_11280	COG1169	isochorismate synthase
JK629_11285	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JK629_11325	COG0367	asparagine synthase
JK629_11335	COG0022	dehydrogenase e1 component
JK629_11355	COG1611	Belongs to the LOG family
JK629_11370	COG0405	Gamma-glutamyltransferase
JK629_11385	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JK629_11405	COG0705	Rhomboid family
JK629_11415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JK629_11440	COG0783	Belongs to the Dps family
JK629_11460	COG0529	Catalyzes the synthesis of activated sulfate
JK629_11470	COG0175	sulfate reduction
JK629_11495	COG2244	polysaccharide biosynthetic process
JK629_11510	COG0463	Glycosyl transferase, family 2
JK629_11510	COG1216	Glycosyl transferase, family 2
JK629_11525	COG0438	transferase activity, transferring glycosyl groups
JK629_11535	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JK629_11600	COG3177	Filamentation induced by cAMP protein fic
JK629_11645	COG2201	protein-glutamate methylesterase activity
JK629_11720	COG1104	cysteine desulfurase activity
JK629_11735	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JK629_11760	COG1074	ATP-dependent DNA helicase activity
JK629_11785	COG4771	TonB-dependent receptor
JK629_11835	COG1028	Short-chain dehydrogenase reductase Sdr
JK629_11840	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JK629_11845	COG0587	DNA-directed DNA polymerase activity
JK629_11860	COG4585	Histidine kinase
JK629_11885	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JK629_11890	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JK629_11915	COG0095	Lipoate-protein ligase
JK629_11925	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
JK629_11930	COG1047	Peptidyl-prolyl cis-trans
JK629_11940	COG2353	YceI-like domain
JK629_11945	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JK629_11950	COG1028	Short-chain dehydrogenase reductase Sdr
JK629_11955	COG3384	dioxygenase
JK629_11960	COG2259	Doxx family
JK629_11970	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JK629_11980	COG0592	DNA-directed DNA polymerase activity
JK629_12005	COG1702	phosphate starvation-inducible protein PhoH
JK629_12010	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JK629_12025	COG1115	amino acid carrier protein
JK629_12040	COG1363	Peptidase, m42
JK629_12085	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JK629_12090	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JK629_12090	COG0116	Belongs to the methyltransferase superfamily
JK629_12105	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JK629_12110	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JK629_12140	COG1104	cysteine desulfurase activity
JK629_12170	COG1418	mRNA catabolic process
JK629_12175	COG0656	L-ascorbic acid biosynthetic process
JK629_12180	COG4974	Belongs to the 'phage' integrase family
JK629_12205	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JK629_12210	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JK629_12215	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JK629_12220	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JK629_12235	COG2270	Major facilitator Superfamily
JK629_12250	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JK629_12260	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JK629_12265	COG1970	mechanosensitive ion channel activity
JK629_12290	COG1522	sequence-specific DNA binding
JK629_12305	COG0693	protein deglycase activity
JK629_12315	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JK629_12330	COG0686	Belongs to the AlaDH PNT family
JK629_12350	COG0802	atpase or kinase
JK629_12355	COG2204	response regulator
JK629_12360	COG1078	dGTPase activity
JK629_12365	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JK629_12370	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
JK629_12370	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JK629_12375	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JK629_12380	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JK629_12395	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JK629_12400	COG1028	Short-chain dehydrogenase reductase Sdr
JK629_12415	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JK629_12420	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JK629_12425	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JK629_12430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JK629_12435	COG0131	Imidazoleglycerol-phosphate dehydratase
JK629_12435	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JK629_12445	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JK629_12455	COG0107	imidazoleglycerol-phosphate synthase activity
JK629_12460	COG0140	phosphoribosyl-ATP diphosphatase activity
JK629_12460	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JK629_12465	COG0598	Magnesium transport protein CorA
JK629_12475	COG4181	ATPase activity
JK629_12480	COG0577	efflux transmembrane transporter activity
JK629_12480	COG1136	(ABC) transporter
JK629_12490	COG3239	Fatty acid desaturase
JK629_12495	COG1278	Cold shock
JK629_12525	COG0586	Pfam SNARE associated Golgi protein
JK629_12620	COG1136	(ABC) transporter
JK629_12635	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JK629_12655	COG0574	Belongs to the PEP-utilizing enzyme family
JK629_12655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JK629_12665	COG2205	protein histidine kinase activity
JK629_12675	COG0071	Belongs to the small heat shock protein (HSP20) family
JK629_12750	COG2116	formate transmembrane transporter activity
JK629_12790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JK629_12800	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JK629_12805	COG1028	Short-chain dehydrogenase reductase Sdr
JK629_12815	COG2226	methyltransferase
JK629_12840	COG0022	dehydrogenase e1 component
JK629_12855	COG0813	purine-nucleoside phosphorylase activity
JK629_12865	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JK629_12875	COG3011	Protein conserved in bacteria
JK629_12885	COG1301	dicarboxylic acid transport
JK629_12890	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JK629_12900	COG0247	lactate metabolic process
JK629_12900	COG0277	FAD linked oxidase domain protein
JK629_12910	COG0438	transferase activity, transferring glycosyl groups
JK629_12915	COG1472	Belongs to the glycosyl hydrolase 3 family
JK629_12925	COG2181	nitrate reductase activity
JK629_12925	COG0247	lactate metabolic process
JK629_12935	COG0247	lactate metabolic process
JK629_12935	COG2181	nitrate reductase activity
JK629_12940	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JK629_12945	COG0860	N-Acetylmuramoyl-L-alanine amidase
JK629_12955	COG0251	oxidation-reduction process
JK629_12965	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JK629_12980	COG0628	permease
JK629_13010	COG0183	Belongs to the thiolase family
JK629_13015	COG0791	NLP P60 protein
JK629_13020	COG0457	Tetratricopeptide repeat
JK629_13030	COG0542	response to heat
JK629_13045	COG2986	histidine ammonia-lyase
JK629_13050	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JK629_13075	COG2197	response regulator
JK629_13090	COG0697	spore germination
JK629_13095	COG0513	Belongs to the DEAD box helicase family
JK629_13100	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JK629_13105	COG4628	conserved protein (DUF2132)
JK629_13115	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JK629_13150	COG2353	YceI-like domain
JK629_13160	COG1741	Belongs to the pirin family
JK629_13210	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JK629_13215	COG3273	potassium ion transport
JK629_13215	COG0471	metal ion transport
JK629_13220	COG0668	transmembrane transport
JK629_13235	COG0300	oxidoreductase activity
JK629_13245	COG1196	nuclear chromosome segregation
JK629_13245	COG3264	Mechanosensitive ion channel
JK629_13250	COG2814	Major facilitator Superfamily
JK629_13255	COG0668	transmembrane transport
JK629_13280	COG1012	belongs to the aldehyde dehydrogenase family
JK629_13285	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JK629_13290	COG2066	Belongs to the glutaminase family
JK629_13300	COG2154	pterin-4-alpha-carbinolamine dehydratase
JK629_13305	COG0217	transcriptional regulatory protein
JK629_13320	COG1454	alcohol dehydrogenase
JK629_13330	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JK629_13360	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JK629_13390	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JK629_13400	COG0259	pyridoxamine-phosphate oxidase activity
JK629_13405	COG1234	tRNA 3'-trailer cleavage
JK629_13415	COG0540	Belongs to the ATCase OTCase family
JK629_13420	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JK629_13440	COG0484	heat shock protein binding
JK629_13455	COG0012	GTP binding
JK629_13475	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JK629_13485	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JK629_13490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JK629_13510	COG4771	TonB-dependent receptor
JK629_13520	COG0302	gtp cyclohydrolase
JK629_13525	COG1136	(ABC) transporter
JK629_13535	COG2205	protein histidine kinase activity
JK629_13535	COG0784	Response regulator, receiver
JK629_13550	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JK629_13575	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JK629_13585	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JK629_13590	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JK629_13605	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JK629_13635	COG0456	acetyltransferase
JK629_13640	COG0156	8-amino-7-oxononanoate synthase activity
JK629_13655	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JK629_13715	COG1393	Belongs to the ArsC family
JK629_13735	COG1333	cytochrome c biogenesis protein
JK629_13735	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JK629_13760	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JK629_13770	COG0424	maF-like protein
JK629_13800	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JK629_13800	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JK629_13815	COG0047	phosphoribosylformylglycinamidine synthase activity
JK629_13815	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JK629_13855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JK629_13915	COG1022	Amp-dependent synthetase and ligase
JK629_13925	COG2076	Multidrug Resistance protein
JK629_13935	COG1250	3-hydroxyacyl-CoA dehydrogenase
JK629_13935	COG1024	Enoyl-CoA hydratase
JK629_13945	COG0183	Belongs to the thiolase family
JK629_13955	COG1960	acyl-CoA dehydrogenase activity
JK629_13985	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
JK629_13990	COG2823	Periplasmic or secreted lipoprotein
JK629_13990	COG1652	LysM domain
JK629_14075	COG1757	Na H antiporter
JK629_14080	COG0450	alkyl hydroperoxide reductase
JK629_14085	COG3118	belongs to the thioredoxin family
JK629_14095	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JK629_14115	COG1674	ftsk spoiiie
JK629_14130	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JK629_14130	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JK629_14135	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JK629_14150	COG4974	Belongs to the 'phage' integrase family
JK629_14235	COG1629	transport
JK629_14245	COG0823	Involved in the tonB-independent uptake of proteins
JK629_14245	COG1506	peptidase
JK629_14260	COG2207	Transcriptional regulator
JK629_14260	COG1609	Transcriptional regulator
JK629_14270	COG0156	8-amino-7-oxononanoate synthase activity
JK629_14305	COG0860	N-Acetylmuramoyl-L-alanine amidase
JK629_14415	COG0629	single-stranded DNA binding
JK629_14445	COG1459	type II secretion system
JK629_14460	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JK629_14560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JK629_14600	COG1595	DNA-templated transcription, initiation
JK629_14625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JK629_14630	COG1120	ATPase activity
JK629_14650	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JK629_14655	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JK629_14685	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JK629_14690	COG4166	transmembrane transport
JK629_14705	COG0254	rRNA binding
JK629_14720	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JK629_14725	COG1132	(ABC) transporter
JK629_14755	COG1028	Short-chain dehydrogenase reductase Sdr
JK629_14760	COG0415	Belongs to the DNA photolyase family
JK629_14775	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JK629_14785	COG2921	Belongs to the UPF0250 family
JK629_14795	COG0514	ATP-dependent DNA helicase (RecQ)
JK629_14800	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JK629_14810	COG1678	Uncharacterized ACR, COG1678
JK629_14845	COG0124	histidyl-tRNA synthetase
JK629_14850	COG0577	efflux transmembrane transporter activity
JK629_14860	COG0359	binds to the 23S rRNA
JK629_14865	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JK629_14870	COG0360	Binds together with S18 to 16S ribosomal RNA
JK629_14875	COG3279	Response regulator of the LytR AlgR family
JK629_14880	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JK629_14890	COG1295	ribonuclease BN
JK629_14900	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JK629_14930	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JK629_14930	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JK629_14940	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JK629_14950	COG0572	uridine kinase
JK629_14975	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JK629_14985	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JK629_14995	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JK629_15010	COG0105	UTP biosynthetic process
JK629_15015	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JK629_15025	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JK629_15030	COG2195	Cleaves the N-terminal amino acid of tripeptides
JK629_15065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JK629_15070	COG0501	Belongs to the peptidase M48B family
JK629_15095	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
JK629_15120	COG0488	(ABC) transporter
JK629_15130	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JK629_15135	COG0300	oxidoreductase activity
JK629_15150	COG1629	transport
JK629_15165	COG0590	tRNA wobble adenosine to inosine editing
JK629_15175	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JK629_15195	COG0542	response to heat
JK629_15230	COG3237	CsbD-like
JK629_15240	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JK629_15260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JK629_15265	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JK629_15275	COG1250	3-hydroxyacyl-CoA dehydrogenase
JK629_15285	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JK629_15295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JK629_15300	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JK629_15315	COG0237	dephospho-CoA kinase activity
JK629_15325	COG0463	Glycosyl transferase, family 2
JK629_15325	COG1216	Glycosyl transferase, family 2
JK629_15345	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JK629_15350	COG0497	DNA recombination
JK629_15375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JK629_15385	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JK629_15390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JK629_15395	COG1611	Belongs to the LOG family
JK629_15400	COG2890	protein-(glutamine-N5) methyltransferase activity
JK629_15405	COG0456	acetyltransferase
JK629_15410	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JK629_15410	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JK629_15415	COG0697	spore germination
JK629_15420	COG1739	Uncharacterized protein family UPF0029