locus-tag	class	description
CL176_00005	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CL176_00010	ENOG410848D	S4 domain protein YaaA
CL176_00015	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CL176_00020	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CL176_00025	ENOG4105VG0	50S ribosomal protein l34
CL176_00030	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
CL176_00055	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CL176_00065	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
CL176_00075	ENOG4105DRR	Transcriptional regulator, GntR family
CL176_00095	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
CL176_00100	ENOG4107QJE	Chromosome Partitioning Protein
CL176_00105	ENOG4105FA0	parb-like partition protein
CL176_00110	ENOG4105VDK	protein, conserved in bacteria
CL176_00115	ENOG4105C3G	gtp-binding protein
CL176_00125	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CL176_00135	ENOG4105BZU	Histidine kinase
CL176_00145	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CL176_00160	ENOG410807C	QueT transporter
CL176_00170	ENOG4106QJ6	Integrase catalytic subunit
CL176_00190	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CL176_00200	ENOG4108Z6B	deaminase
CL176_00225	ENOG4105C9K	Endothelin-converting enzyme 1
CL176_00230	ENOG4105C6E	dna polymerase iii
CL176_00235	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
CL176_00240	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CL176_00245	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
CL176_00250	ENOG4105X0R	protein from nitrogen regulatory protein P-II
CL176_00265	ENOG41060K3	Methyltransferase
CL176_00270	ENOG4105VC4	domain protein
CL176_00275	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
CL176_00285	ENOG4108R3E	Dna-3-methyladenine glycosylase i
CL176_00290	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
CL176_00295	ENOG4107VFR	oxidoreductase
CL176_00300	ENOG41085PJ	rdd domain containing protein
CL176_00305	ENOG4105D07	Signal peptide peptidase, SppA
CL176_00310	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CL176_00315	ENOG4105CHM	Aminotransferase
CL176_00320	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
CL176_00325	ENOG4108UMI	ABC transporter, permease
CL176_00330	ENOG4105G6Z	alkaline phosphatase
CL176_00345	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
CL176_00350	ENOG4105D01	(LipO)protein
CL176_00355	ENOG4105D01	(LipO)protein
CL176_00360	ENOG4105DCI	Phosphohydrolase
CL176_00365	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
CL176_00390	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
CL176_00395	ENOG4105EG2	ABC transporter, permease
CL176_00400	ENOG4108IJ9	(ABC) transporter
CL176_00405	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
CL176_00410	ENOG4105DIH	basic membrane
CL176_00435	ENOG4105C19	ABC transporter
CL176_00440	ENOG4108JE9	extracellular solute-binding protein family 1
CL176_00455	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
CL176_00460	ENOG4105DRS	transport system, permease
CL176_00465	ENOG4108IJ9	(ABC) transporter
CL176_00470	ENOG4108JE9	extracellular solute-binding protein family 1
CL176_00475	ENOG4105D2N	Aldolase
CL176_00480	ENOG4105C6N	Formate acetyltransferase
CL176_00485	ENOG4105F1A	Pyruvate formate-lyase
CL176_00490	ENOG4105C28	cystathionine
CL176_00495	ENOG4105C87	Aminotransferase class I and II
CL176_00505	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CL176_00510	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
CL176_00515	ENOG4108Z66	YbaK ebsC protein
CL176_00530	ENOG41082DI	50s ribosomal protein l31
CL176_00540	ENOG4105ZMH	deoxynucleoside kinase
CL176_00545	ENOG4108IJ7	Glycine betaine
CL176_00560	ENOG4107EFR	Flavocytochrome c
CL176_00575	ENOG4105CPQ	Dehydrogenase
CL176_00580	ENOG4105CHM	Aminotransferase
CL176_00585	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CL176_00620	ENOG4108V0P	LemA family
CL176_00635	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
CL176_00640	ENOG4105C1J	atp-dependent rna helicase
CL176_00645	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
CL176_00650	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CL176_00665	ENOG4105C37	(CBS) domain
CL176_00670	ENOG4108VQJ	O-methyltransferase
CL176_00675	ENOG410667J	hydrolase
CL176_00685	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CL176_00690	ENOG4105BZU	Histidine kinase
CL176_00710	ENOG4105Q2H	domain protein
CL176_00715	ENOG4105C0H	protease
CL176_00730	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
CL176_00760	ENOG4105CH2	amidohydrolase
CL176_00770	ENOG4105C3F	Signal peptidase i
CL176_00775	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CL176_00780	ENOG4108S4H	thioesterase Superfamily protein
CL176_00785	ENOG41072GX	Peptidase M22 Glycoprotease
CL176_00790	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
CL176_00800	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CL176_00805	ENOG4105C5H	ABC transporter
CL176_00810	ENOG4105C8F	Beta-lactamase domain protein
CL176_00815	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
CL176_00820	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CL176_00850	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
CL176_00885	ENOG4107X35	defense response to bacterium
CL176_00895	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
CL176_00900	ENOG4108UJD	30S ribosomal protein S9
CL176_00940	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CL176_00950	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
CL176_00955	ENOG4108KGH	TRANSCRIPTIONal
CL176_00985	ENOG4108Q3X	Transcriptional regulator
CL176_00995	ENOG4108X4Q	Hydrolase
CL176_01100	ENOG4105CN9	Peptidase m42 family protein
CL176_01105	ENOG4105DF9	Lipoate-protein, ligase
CL176_01115	ENOG4105D9M	gamma-glutamylcysteine synthetase
CL176_01210	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
CL176_01220	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CL176_01235	ENOG4105CGK	Exodeoxyribonuclease III
CL176_01240	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
CL176_01250	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
CL176_01255	ENOG4108R6K	riboflavin synthase, subunit alpha
CL176_01260	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
CL176_01265	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CL176_01270	ENOG4105C59	p-type ATPase
CL176_01280	ENOG4105CSM	endonuclease III
CL176_01285	ENOG4108MRH	transcriptional regulatory protein
CL176_01300	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
CL176_01305	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
CL176_01330	ENOG4105CH7	arginosuccinase
CL176_01335	ENOG4105NRR	Uncharacterized protein conserved in bacteria (DUF2188)
CL176_01340	ENOG4107EFR	Flavocytochrome c
CL176_01395	ENOG4105F9F	transposase
CL176_01415	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CL176_01420	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
CL176_01425	ENOG4108HRK	Histidine kinase
CL176_01430	ENOG4105DY9	regulatoR
CL176_01440	ENOG41067MG	lrgb family
CL176_01460	ENOG4105DR4	Methyltransferase
CL176_01495	ENOG4107RZC	phospholipase d
CL176_01510	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
CL176_01515	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
CL176_01520	ENOG4105C4R	Atp-dependent dna helicase
CL176_01525	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
CL176_01535	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CL176_01540	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CL176_01545	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CL176_01550	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
CL176_01555	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
CL176_01560	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
CL176_01565	ENOG4105DC1	bifunctional purine biosynthesis protein purh
CL176_01570	ENOG4105C12	Phosphoribosylglycinamide synthetase
CL176_01575	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
CL176_01580	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
CL176_01585	ENOG4107T2D	Phosphoribosylaminoimidazolesuccinocarboxamide synthase
CL176_01590	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
CL176_01600	ENOG4105C5B	carbamate kinase
CL176_01605	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CL176_01610	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CL176_01635	ENOG4105DC8	reductase
CL176_01640	ENOG4107BMA	Transglycosylase associated protein
CL176_01650	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
CL176_01660	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CL176_01670	ENOG4105C88	aminopeptidase
CL176_01675	ENOG4105NQC	Flavodoxin
CL176_01680	ENOG4105CMR	udp-glucose 4-epimerase
CL176_01690	ENOG4108KGH	TRANSCRIPTIONal
CL176_01695	ENOG4108PQP	glycosyl transferase group 1
CL176_01720	ENOG4105C5I	Dehydrogenase
CL176_01755	ENOG4105BZ1	(ABC) transporter
CL176_01760	ENOG4105KWG	Pfam:DUF1696
CL176_01765	ENOG4105EVI	UPF0374 protein
CL176_01770	ENOG4108IUM	Glycogen debranching enzyme
CL176_01775	ENOG4105CHU	acetyl-coa acetyltransferase
CL176_01780	ENOG4108J59	Extracellular solute-binding protein, family 5
CL176_01785	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CL176_01790	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CL176_01800	ENOG4108JQ7	(ABC) transporter
CL176_01810	ENOG4108J59	Extracellular solute-binding protein, family 5
CL176_01845	ENOG4105DKT	Transcriptional regulator
CL176_01850	ENOG4107QRI	Phosphoketolase
CL176_01855	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
CL176_01860	ENOG4105DYB	Isoaspartyl dipeptidase
CL176_01865	ENOG4105CMT	Dihydroxyacetone kinase
CL176_01870	ENOG4108UTZ	Dihydroxyacetone kinase
CL176_01875	ENOG4105VDH	Dihydroxyacetone kinase
CL176_01880	ENOG4105D01	(LipO)protein
CL176_01890	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
CL176_01900	ENOG4105E98	transcriptional regulator DeoR family
CL176_01920	ENOG4105DMW	Dehydrogenase reductase
CL176_01925	ENOG4105CNT	hydrolase family 2
CL176_01930	ENOG4108M60	Transcriptional regulator
CL176_01935	ENOG4105D7K	pfkb domain protein
CL176_01940	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
CL176_01945	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
CL176_01950	ENOG4108UHU	Aldolase
CL176_01960	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
CL176_01970	ENOG4105ETZ	PTS System
CL176_01975	ENOG4105F3R	pts system mannose fructose sorbose family iid
CL176_01985	ENOG4108JQ1	Dehydrogenase
CL176_02015	ENOG4108YZG	isomerase
CL176_02020	ENOG4105ETE	Transcriptional regulator (LacI family
CL176_02025	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
CL176_02100	ENOG4105CE9	30S ribosomal protein S2
CL176_02135	ENOG4105IG6	Phage terminase, large subunit
CL176_02160	ENOG4108UUM	single-stranded DNA-binding protein
CL176_02185	ENOG4108PNI	recT protein
CL176_02195	ENOG4108NF7	phage-type endonuclease
CL176_02285	ENOG4108RVA	ribokinase
CL176_02290	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
CL176_02295	ENOG4105C2J	ABC transporter
CL176_02300	ENOG4105CNN	ABC, transporter
CL176_02305	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
CL176_02320	ENOG4105CMG	Carbohydrate kinase
CL176_02325	ENOG4105C5Y	PTS System
CL176_02355	ENOG4105EKQ	RNA-directed DNA polymerase
CL176_02360	ENOG4105CHR	reductase
CL176_02365	ENOG4105EMD	TRANSCRIPTIONal
CL176_02375	ENOG410787A	Pts system, glucitol sorbitol-specific
CL176_02380	ENOG4105DZY	Pts system, glucitol sorbitol-specific
CL176_02385	ENOG4105VI0	Pts system, glucitol sorbitol-specific
CL176_02390	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
CL176_02395	ENOG4107YBY	Hydrolase
CL176_02410	ENOG4105E98	transcriptional regulator DeoR family
CL176_02455	ENOG41090UW	PTS System
CL176_02460	ENOG4105DT3	PTS system, galactitol-specific IIc component
CL176_02465	ENOG4107WTH	Galactitol-1-phosphate dehydrogenase
CL176_02470	ENOG4105D2M	Aldolase
CL176_02475	ENOG4105DE4	1-phosphofructokinase
CL176_02480	ENOG410667J	hydrolase
CL176_02500	ENOG4105F5W	AtP-binding protein
CL176_02510	ENOG4105DQ6	Transposase
CL176_02520	ENOG4107EFR	Flavocytochrome c
CL176_02525	ENOG4107EFR	Flavocytochrome c
CL176_02540	ENOG4105EMD	TRANSCRIPTIONal
CL176_02575	ENOG4105C5Y	PTS System
CL176_02605	ENOG4105EMD	TRANSCRIPTIONal
CL176_02610	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
CL176_02625	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CL176_02645	ENOG4108HCJ	Hydrolase
CL176_02660	ENOG4105C0A	alcohol dehydrogenase
CL176_02670	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
CL176_02675	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
CL176_02680	ENOG4107RUZ	Sss sodium solute transporter superfamily
CL176_02685	ENOG4105CK5	oxidoreductase
CL176_02695	ENOG4105VCP	PTS System
CL176_02705	ENOG4105EDK	PfkB domain protein
CL176_02710	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
CL176_02715	ENOG4105D2N	Aldolase
CL176_02720	ENOG4105C26	Dehydrogenase
CL176_02750	ENOG4105KXQ	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CL176_02760	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
CL176_02765	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CL176_02790	ENOG41090U3	tautomerase
CL176_02815	ENOG4105DG4	malate L-lactate dehydrogenase
CL176_02820	ENOG4107REC	cytoplasmic protein
CL176_02825	ENOG4105G5A	Protein of unknown function (DUF2877)
CL176_02835	ENOG4105S0E	allantoin catabolism protein
CL176_02840	ENOG4105G9B	Transcriptional regulator
CL176_02845	ENOG4105C5R	Aminotransferase
CL176_02850	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
CL176_02855	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
CL176_02860	ENOG4107RNN	dihydropyrimidinase (EC 3.5.2.2)
CL176_02875	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CL176_02890	ENOG4105C5I	Dehydrogenase
CL176_02910	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
CL176_02915	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CL176_02925	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
CL176_02935	ENOG4108MEK	Metal-binding protein YodA
CL176_02940	ENOG4105DSE	periplasmic solute binding protein
CL176_02950	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CL176_02955	ENOG4107QPK	)-transporter
CL176_02960	ENOG4108VK3	Cupin 2 Conserved Barrel Domain Protein
CL176_02965	ENOG4108I0Z	Aconitate hydratase
CL176_02975	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CL176_02980	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CL176_02985	ENOG4105E0A	ABC, transporter
CL176_02990	ENOG4105EHG	Permease protein
CL176_03000	ENOG4105DQ6	Transposase
CL176_03015	ENOG4105DQ6	Transposase
CL176_03030	ENOG4108HW3	(ABC) transporter
CL176_03050	ENOG4105I7V	membrAne
CL176_03055	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
CL176_03065	ENOG4105DEN	Luciferase family
CL176_03085	ENOG4108JJB	ABC transporter
CL176_03090	ENOG4105CHF	Glutathione S-transferase
CL176_03095	ENOG4105RKW	reductase (By
CL176_03105	ENOG4108MXZ	Esterase
CL176_03110	ENOG4105DFA	alanine racemase domain protein
CL176_03145	ENOG4107NBY	Membrane
CL176_03150	ENOG4105G5W	regulator Fur family
CL176_03155	ENOG4105C31	Tryptophanyl-tRNA synthetase
CL176_03160	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
CL176_03165	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
CL176_03175	ENOG4105DPN	Oligoendopeptidase f
CL176_03180	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
CL176_03195	ENOG4105CN9	Peptidase m42 family protein
CL176_03200	ENOG4108VDD	TRNA binding domain protein
CL176_03210	ENOG4105DFU	Cell wall formation (By similarity)
CL176_03220	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
CL176_03225	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
CL176_03230	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
CL176_03245	ENOG4105C22	threonyL-tRNA synthetase
CL176_03260	ENOG4108RG0	uracil-dna glycosylase
CL176_03265	ENOG4108DBC	nitroreductase
CL176_03275	ENOG4105BZ1	(ABC) transporter
CL176_03280	ENOG4105BZ1	(ABC) transporter
CL176_03285	ENOG4105F9F	transposase
CL176_03295	ENOG4105DIK	(ABC) transporter
CL176_03300	ENOG4107RPQ	ABC transporter
CL176_03305	ENOG4107RBD	ABC, transporter
CL176_03310	ENOG4105DSE	periplasmic solute binding protein
CL176_03320	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CL176_03325	ENOG4105VJV	50s ribosomal protein L35
CL176_03330	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CL176_03335	ENOG4105E2K	Glycosyl transferase (Group 1
CL176_03340	ENOG4105T58	Dithiol-disulfide isomerase
CL176_03345	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CL176_03350	ENOG4105EMS	pseudouridine synthase
CL176_03355	ENOG4105CJW	magnesium transporter
CL176_03380	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
CL176_03385	ENOG4105KRI	phosphocarrier protein (HPr
CL176_03390	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
CL176_03400	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
CL176_03405	ENOG4105CQW	ribosome biogenesis GTPase YqeH
CL176_03410	ENOG4105HBR	Rna-binding protein
CL176_03415	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
CL176_03420	ENOG4108WF2	Metal Dependent Phosphohydrolase
CL176_03430	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CL176_03435	ENOG4105CDE	UPF0348 protein
CL176_03450	ENOG41067VY	50S ribosomal protein L32
CL176_03460	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CL176_03470	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CL176_03475	ENOG4105BZA	Phosphoglycerate kinase
CL176_03480	ENOG4105CP7	Triose-phosphate isomerase
CL176_03490	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CL176_03495	ENOG4105C7K	acetolactate synthase
CL176_03510	ENOG4105XZU	Preprotein translocase, subunit SecG
CL176_03520	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
CL176_03525	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CL176_03530	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
CL176_03535	ENOG4105CN5	Metallo-Beta-Lactamase
CL176_03575	ENOG4105DC7	peptidase M24
CL176_03585	ENOG4105M7K	Involved in the transcription termination process (By similarity)
CL176_03595	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CL176_03600	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CL176_03610	ENOG4105DX0	Hemolysin A
CL176_03615	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
CL176_03620	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CL176_03625	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
CL176_03630	ENOG4107YB9	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CL176_03640	ENOG4105D82	Glutamate dehydrogenase
CL176_03655	ENOG410854A	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CL176_03660	ENOG4105EA8	2-Nitropropane dioxygenase
CL176_03670	ENOG4105CHR	reductase
CL176_03675	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CL176_03680	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
CL176_03685	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CL176_03690	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
CL176_03695	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
CL176_03700	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
CL176_03715	ENOG4105C7S	Dehydrogenase
CL176_03725	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
CL176_03745	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CL176_03760	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CL176_03770	ENOG4105WBI	UPF0223 protein
CL176_03775	ENOG4105ECY	inositol monophosphatase
CL176_03780	ENOG4105CI3	gtp-binding protein typa
CL176_03795	ENOG4105CNI	cell division protein FtsW
CL176_03800	ENOG4105WUC	UPF0298 protein
CL176_03805	ENOG4106H78	methyltransferase
CL176_03810	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CL176_03815	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
CL176_03835	ENOG4105CT1	(ABC) transporter
CL176_03840	ENOG4105EAD	ABC transporter
CL176_03845	ENOG4105DRP	amino acid AbC transporter
CL176_03850	ENOG4105CI1	PTS System
CL176_03855	ENOG41090MY	MarR family Transcriptional regulator
CL176_03865	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
CL176_03870	ENOG4107XC4	flavin reductase domain protein, FMN-binding
CL176_03885	ENOG41067VN	Glutaredoxin
CL176_03890	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
CL176_03935	ENOG4107R8B	5'-nucleotidase
CL176_03940	ENOG4105MMD	transcriptional regulator
CL176_03945	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
CL176_03955	ENOG4108W5N	phosphatidylglycerophosphatase a
CL176_03960	ENOG4105CAY	ferredoxin--nadp reductase
CL176_03970	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CL176_03975	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CL176_03980	ENOG4107QYV	phosphohexose isomerase
CL176_04100	ENOG4105C75	arginyL-tRNA synthetase
CL176_04210	ENOG4105CM4	permease protein
CL176_04215	ENOG4108IPW	abc transporter atp-binding protein
CL176_04240	ENOG4108WZW	RNA polymerase sigma
CL176_04295	ENOG4105E5H	Transposase
CL176_04310	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CL176_04320	ENOG4107X35	defense response to bacterium
CL176_04325	ENOG4105C8T	Leucyl-tRNA synthetase
CL176_04375	ENOG4107YJ4	chain length determinant protein
CL176_04380	ENOG4105D3Q	Sugar transferase
CL176_04385	ENOG4106WTF	Glycosyl transferase, family 2
CL176_04390	ENOG4108KMV	Glycosyl transferase (Group 1
CL176_04395	ENOG4105K64	Glycosyl transferase, family 2
CL176_04405	ENOG4108KMV	Glycosyl transferase (Group 1
CL176_04410	ENOG4107S6X	Glycosyl transferase, family 2
CL176_04435	ENOG4105K64	Glycosyl transferase, family 2
CL176_04465	ENOG41060M0	Crispr-associated protein, cse4 family
CL176_04470	ENOG4108VWQ	crispr-associated protein
CL176_04480	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
CL176_04510	ENOG4105DQ6	Transposase
CL176_04520	ENOG4108J59	Extracellular solute-binding protein, family 5
CL176_04525	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CL176_04545	ENOG4107RUE	extracellular solute-binding protein family 1
CL176_04550	ENOG4105D38	putrescine abc transporter
CL176_04555	ENOG4105F38	ABC transporter, permease
CL176_04560	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CL176_04585	ENOG4107QSE	Dipeptidase
CL176_04590	ENOG4108RWN	rrna methyltransferase
CL176_04605	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CL176_04630	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CL176_04650	ENOG4105C98	muts2 protein
CL176_04655	ENOG4105K63	Thioredoxin
CL176_04660	ENOG4105DCF	alanine dehydrogenase
CL176_04700	ENOG4105D8X	mechanosensitive ion channel
CL176_04715	ENOG4105ETE	Transcriptional regulator (LacI family
CL176_04725	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
CL176_04730	ENOG4105W5Q	DNA repair protein (RadC
CL176_04735	ENOG4105VEQ	Cold shock protein
CL176_04755	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
CL176_04765	ENOG41083J0	(ABC) transporter
CL176_04770	ENOG4105C4B	ABC transporter, permease
CL176_04775	ENOG4105C9K	Endothelin-converting enzyme 1
CL176_04780	ENOG4105C9K	Endothelin-converting enzyme 1
CL176_04790	ENOG4105C9K	Endothelin-converting enzyme 1
CL176_04800	ENOG4105CI1	PTS System
CL176_04815	ENOG4105DFF	Rod shape-determining protein mreb
CL176_04820	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
CL176_04830	ENOG4106PMH	Extracellular solute-binding protein family 3
CL176_04855	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
CL176_04865	ENOG41087YS	Phage shock protein A
CL176_04885	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CL176_04900	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
CL176_04910	ENOG4105C5Y	PTS System
CL176_04915	ENOG4105CG3	alpha amylase, catalytic region
CL176_04920	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CL176_04930	ENOG4107RUY	(E1 component), alpha subunit
CL176_04940	ENOG4107QKR	Dehydrogenase
CL176_04945	ENOG4105EKQ	RNA-directed DNA polymerase
CL176_04955	ENOG4105MYU	Immunoglobulin A1 protease
CL176_04965	ENOG4108ZJ4	polysaccharide deacetylase
CL176_04970	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
CL176_04975	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
CL176_04980	ENOG410667J	hydrolase
CL176_04985	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CL176_04990	ENOG4105VB9	50S ribosomal protein l28
CL176_04995	ENOG4108ZAA	Alkaline-shock protein
CL176_05000	ENOG4105DP4	dak2 domain fusion protein ylov
CL176_05005	ENOG4105CB5	ATP-dependent DNA helicase recG
CL176_05010	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
CL176_05015	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CL176_05020	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
CL176_05035	ENOG4105D1H	recombination factor protein RarA
CL176_05040	ENOG4105C3J	Cysteine desulfurase
CL176_05050	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CL176_05060	ENOG4105JRK	feS assembly protein SufD
CL176_05070	ENOG4108UNV	SUF system FeS assembly protein, NifU family
CL176_05075	ENOG4105DIW	FeS assembly protein SUFB
CL176_05100	ENOG4105C7H	Helicase, RecD TraA family
CL176_05105	ENOG4109050	May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG)
CL176_05120	ENOG4108HQR	Glycine betaine
CL176_05140	ENOG410667J	hydrolase
CL176_05145	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CL176_05155	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
CL176_05160	ENOG4105VPH	UPF0473 protein
CL176_05165	ENOG4105HHA	aminodeoxychorismate lyase
CL176_05175	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CL176_05185	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
CL176_05190	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
CL176_05195	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
CL176_05215	ENOG4105WH1	Two component transcriptional regulator luxr family
CL176_05220	ENOG4105W8X	HesB YadR YfhF-family protein
CL176_05225	ENOG4108REF	Sporulation integral membrane protein ytvi
CL176_05235	ENOG4107R7Y	intracellular protease Pfpi family
CL176_05240	ENOG4108Z5K	methylglyoxal synthase
CL176_05245	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CL176_05250	ENOG4105EKQ	RNA-directed DNA polymerase
CL176_05255	ENOG4105EKQ	RNA-directed DNA polymerase
CL176_05275	ENOG4105C02	permease
CL176_05280	ENOG4105F7J	membrane-bound serine protease
CL176_05285	ENOG4105DI5	UPF0365 protein
CL176_05300	ENOG4105CE9	30S ribosomal protein S2
CL176_05305	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CL176_05310	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CL176_05315	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CL176_05320	ENOG4107EFR	Flavocytochrome c
CL176_05335	ENOG4105KNE	Phosphatidate cytidylyltransferase
CL176_05340	ENOG4105DZP	Membrane-associated zinc metalloprotease
CL176_05345	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
CL176_05350	ENOG4108YYH	Nadph-dependent fmn reductase
CL176_05355	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
CL176_05360	ENOG4105CHV	Transcription elongation factor NusA
CL176_05365	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
CL176_05380	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
CL176_05385	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
CL176_05390	ENOG4105DTN	riboflavin biosynthesis protein ribF
CL176_05400	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CL176_05405	ENOG4105CFG	Acts as a chaperone (By similarity)
CL176_05410	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CL176_05415	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CL176_05420	ENOG4105CY2	Citrate transporter
CL176_05425	ENOG4105HUF	DNA protection during starvation protein
CL176_05430	ENOG4105WZW	rhodanese family
CL176_05455	ENOG4105DZC	cytosine deaminase
CL176_05460	ENOG4105C26	Dehydrogenase
CL176_05470	ENOG41090UD	(LipO)protein
CL176_05515	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
CL176_05550	ENOG4106QJ6	Integrase catalytic subunit
CL176_05625	ENOG41067QW	Transcriptional regulator
CL176_05660	ENOG4105W5Q	DNA repair protein (RadC
CL176_05665	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CL176_05680	ENOG41071EZ	rRNA adenine N-6-methyltransferase
CL176_05685	ENOG4106JUT	Streptomycin 3''-adenylyltransferase
CL176_05690	ENOG4105ZX1	Transposase C
CL176_05695	ENOG4108KU9	integrase family
CL176_05700	ENOG4108FPN	Integrase
CL176_05760	ENOG4105FA0	parb-like partition protein
CL176_05765	ENOG4107QJE	Chromosome Partitioning Protein
CL176_05800	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CL176_05805	ENOG4105DPH	UPF0371 protein
CL176_05815	ENOG4108EKI	Dehydrogenase
CL176_05825	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
CL176_05835	ENOG4108K5P	(LipO)protein
CL176_05845	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
CL176_05850	ENOG4105E5Q	amino acid AbC transporter
CL176_05870	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
CL176_05890	ENOG4105ECQ	AraC Family Transcriptional Regulator
CL176_05900	ENOG4105C7J	ABC transporter, permease
CL176_05910	ENOG4105F23	Fibronectin-binding protein
CL176_05915	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
CL176_05920	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CL176_05925	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CL176_05930	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
CL176_05940	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
CL176_05945	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
CL176_05950	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CL176_05955	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
CL176_05960	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CL176_05965	ENOG4105C79	DNA protecting protein DprA
CL176_05970	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CL176_05975	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
CL176_05990	ENOG4105VSD	UPF0346 protein
CL176_05995	ENOG4108UT2	hemolysin iii
CL176_06000	ENOG410841Q	phosphoesterase PA-phosphatase related protein
CL176_06010	ENOG4105II7	pyrroline-5-carboxylate reductase
CL176_06015	ENOG4105C5H	ABC transporter
CL176_06020	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
CL176_06025	ENOG4105CKU	formyltetrahydrofolate synthetase
CL176_06045	ENOG4105FJ0	thiamine
CL176_06050	ENOG4105DJV	ribulose-phosphate 3-epimerase
CL176_06055	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
CL176_06060	ENOG4105D9P	serine threonine protein kinase
CL176_06065	ENOG4108ZF3	Phosphatase
CL176_06070	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CL176_06075	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CL176_06080	ENOG4105C25	Primosomal protein n'
CL176_06085	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
CL176_06090	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
CL176_06095	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CL176_06100	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
CL176_06105	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
CL176_06110	ENOG4105KXQ	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CL176_06155	ENOG4107V8I	Glycosyl transferases group 1
CL176_06160	ENOG4105W2C	Glycosyl transferase
CL176_06240	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CL176_06250	ENOG4107RBB	ABC transporter, permease
CL176_06270	ENOG4105CH2	amidohydrolase
CL176_06275	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
CL176_06280	ENOG4105EXC	Acyl-transferase
CL176_06285	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CL176_06290	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
CL176_06305	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
CL176_06315	ENOG4107U9T	Pfam:Ribonuclease_BN
CL176_06330	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
CL176_06345	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
CL176_06350	ENOG4106TNF	Periplasmic binding protein
CL176_06355	ENOG4105CDA	abc transporter atp-binding protein
CL176_06365	ENOG4105E5Q	amino acid AbC transporter
CL176_06375	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
CL176_06390	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
CL176_06395	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CL176_06400	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CL176_06410	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
CL176_06415	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
CL176_06425	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CL176_06455	ENOG4105HS6	binding-protein-dependent transport systems inner membrane Component
CL176_06465	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CL176_06485	ENOG4106QJ6	Integrase catalytic subunit
CL176_06520	ENOG4107EFR	Flavocytochrome c
CL176_06525	ENOG4107EFR	Flavocytochrome c
CL176_06550	ENOG4107EFR	Flavocytochrome c
CL176_06560	ENOG4107EFR	Flavocytochrome c
CL176_06590	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CL176_06600	ENOG4105VG1	fes assembly suf system protein
CL176_06605	ENOG4108KP7	hydrolase
CL176_06615	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CL176_06620	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CL176_06630	ENOG4108Z40	Transcriptional regulator
CL176_06640	ENOG4108IJ8	ABC transporter
CL176_06645	ENOG4105VB6	UPF0109 protein
CL176_06650	ENOG4105K5M	30s ribosomal protein S16
CL176_06660	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
CL176_06670	ENOG4105EDE	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1 (By similarity)
CL176_06700	ENOG4107EFR	Flavocytochrome c
CL176_06715	ENOG4105EKQ	RNA-directed DNA polymerase
CL176_06720	ENOG4105EKQ	RNA-directed DNA polymerase
CL176_06725	ENOG4107RBJ	symporter
CL176_06730	ENOG4105C2X	Arabinose 5-phosphate isomerase
CL176_06735	ENOG4105F8D	glycoside hydrolase family 4
CL176_06740	ENOG4105CI1	PTS System
CL176_06750	ENOG4105ETE	Transcriptional regulator (LacI family
CL176_06765	ENOG4105EVU	fructokinase
CL176_06775	ENOG4105C5Y	PTS System
CL176_06785	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CL176_06795	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CL176_06800	ENOG4108I5D	sulfate abc transporter
CL176_06805	ENOG4105F38	ABC transporter, permease
CL176_06810	ENOG4105C26	Dehydrogenase
CL176_06815	ENOG4105C26	Dehydrogenase
CL176_06830	ENOG4105E5H	Transposase
CL176_06845	ENOG4105C59	p-type ATPase
CL176_06850	ENOG4105CK2	sodium dicarboxylate symporter
CL176_06865	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
CL176_06885	ENOG4107PP3	Acetylornithine deacetylase
CL176_06890	ENOG41088SP	formiminoglutamate hydrolase
CL176_06895	ENOG4105D6U	Sodium Glutamate Symporter
CL176_06910	ENOG410626B	catechol 1,2-dioxygenase
CL176_06915	ENOG4108HW3	(ABC) transporter
CL176_06935	ENOG4105CH2	amidohydrolase
CL176_06955	ENOG4105D01	(LipO)protein
CL176_06965	ENOG4108ZMX	Domain of unknown function (DU1801)
CL176_07045	ENOG4107PP3	Acetylornithine deacetylase
CL176_07070	ENOG4105D3R	alkyl hydroperoxide reductase
CL176_07095	ENOG4105DM4	PTS System
CL176_07105	ENOG4105DG6	mannose-6-phosphate isomerase
CL176_07110	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
CL176_07125	ENOG4105H67	Protein of unknown function (DUF421)
CL176_07135	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
CL176_07140	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
CL176_07145	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
CL176_07150	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
CL176_07160	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
CL176_07165	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
CL176_07180	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
CL176_07190	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
CL176_07195	ENOG4105CXT	aspartate transcarbamylase
CL176_07200	ENOG4105BZ1	(ABC) transporter
CL176_07205	ENOG4105BZ1	(ABC) transporter
CL176_07210	ENOG4107ZXU	DSBA oxidoreductase
CL176_07215	ENOG41080E8	Transcriptional regulator, Spx MgsR family
CL176_07220	ENOG4108ZHJ	Organic hydroperoxide resistance protein
CL176_07230	ENOG4105BZ1	(ABC) transporter
CL176_07240	ENOG4105PW4	Sugar fermentation stimulation protein homolog
CL176_07275	ENOG4105D98	threonine synthase
CL176_07295	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
CL176_07310	ENOG4105C34	Pseudouridine synthase
CL176_07315	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
CL176_07330	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
CL176_07335	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CL176_07345	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
CL176_07365	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CL176_07370	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
CL176_07375	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
CL176_07380	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CL176_07385	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CL176_07390	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
CL176_07395	ENOG4105BZ4	penicillin-binding protein
CL176_07400	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CL176_07415	ENOG4105CSM	endonuclease III
CL176_07450	ENOG4105K70	DNA-binding protein
CL176_07455	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CL176_07460	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CL176_07465	ENOG4105CAT	Cytidine monophosphate kinase
CL176_07480	ENOG4105FE9	pseudouridine synthase
CL176_07485	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
CL176_07490	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
CL176_07505	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
CL176_07525	ENOG4105CTQ	phosphohexokinase
CL176_07530	ENOG4105C0B	DNA polymerase III (alpha subunit)
CL176_07535	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
CL176_07540	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CL176_07555	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
CL176_07560	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
CL176_07570	ENOG4105BZ1	(ABC) transporter
CL176_07575	ENOG4105K46	50S ribosomal protein l27
CL176_07585	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
CL176_07590	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
CL176_07595	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CL176_07600	ENOG4105CEV	competence damage-inducible protein
CL176_07605	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
CL176_07635	ENOG4105UIB	(ABC) transporter
CL176_07640	ENOG4108JQ9	ABC transporter
CL176_07645	ENOG4105DIH	basic membrane
CL176_07650	ENOG4105CNU	cell division protein FtsK
CL176_07655	ENOG410855V	Acylphosphatase
CL176_07660	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
CL176_07665	ENOG4105GR3	Histidine kinase
CL176_07675	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
CL176_07680	ENOG4107YZP	Rhodanese domain protein
CL176_07685	ENOG4105DKQ	ROK family
CL176_07695	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
CL176_07715	ENOG4107RF6	penicillin-binding protein
CL176_07730	ENOG4105VUC	UPF0237 protein
CL176_07735	ENOG4105CAG	UPF0210 protein
CL176_07740	ENOG4105DQ6	Transposase
CL176_07750	ENOG4105C1J	atp-dependent rna helicase
CL176_07755	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
CL176_07760	ENOG4105SFS	phosphoesterase RecJ domain protein
CL176_07770	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CL176_07775	ENOG4105VIE	preprotein translocase, subunit YajC
CL176_07780	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
CL176_07790	ENOG4105F6E	Acyl-transferase
CL176_07795	ENOG4105VXM	UPF0154 protein
CL176_07810	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CL176_07815	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CL176_07825	ENOG4108IXY	short-chain dehydrogenase reductase
CL176_07830	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
CL176_07835	ENOG4105EXC	Acyl-transferase
CL176_07840	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CL176_07845	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
CL176_07850	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
CL176_07855	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
CL176_07860	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
CL176_07865	ENOG4107YR5	Diacylglycerol kinase
CL176_07870	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
CL176_07880	ENOG4105C9A	Phoh family
CL176_07885	ENOG4105KTH	gatB Yqey
CL176_07890	ENOG4105VCC	30S ribosomal protein S21
CL176_07895	ENOG4105N80	Ferric uptake regulator, Fur family
CL176_07900	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
CL176_07905	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
CL176_07910	ENOG4105C9M	aspartyl-trna synthetase
CL176_07930	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
CL176_07935	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
CL176_07940	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CL176_07955	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
CL176_07960	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CL176_07970	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
CL176_07980	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
CL176_07985	ENOG4105VND	Ribonuclease
CL176_08000	ENOG4105CBD	Diacylglycerol kinase
CL176_08020	ENOG4105CH2	amidohydrolase
CL176_08025	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
CL176_08035	ENOG4105C8Y	Acetylornithine aminotransferase
CL176_08040	ENOG4105CAS	nag kinase
CL176_08050	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
CL176_08055	ENOG4105C3J	Cysteine desulfurase
CL176_08065	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
CL176_08070	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CL176_08075	ENOG4105CDA	abc transporter atp-binding protein
CL176_08080	ENOG4105E5Q	amino acid AbC transporter
CL176_08085	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
CL176_08095	ENOG4108YZ4	nudix hydrolase
CL176_08105	ENOG4105CDW	Resistance protein
CL176_08115	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
CL176_08130	ENOG41067XK	integral membrane protein
CL176_08140	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
CL176_08145	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
CL176_08150	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CL176_08155	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CL176_08160	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CL176_08165	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
CL176_08170	ENOG4105CJN	penicillin-binding protein
CL176_08180	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CL176_08185	ENOG4108V6E	Cell division protein mraZ
CL176_08200	ENOG4105DFF	Rod shape-determining protein mreb
CL176_08205	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CL176_08215	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
CL176_08225	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CL176_08230	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CL176_08235	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CL176_08240	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CL176_08245	ENOG4107104	thymidine kinase
CL176_08255	ENOG4105DMS	mur ligase
CL176_08260	ENOG4108UQV	Membrane
CL176_08275	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
CL176_08285	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CL176_08290	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CL176_08295	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
CL176_08300	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
CL176_08305	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
CL176_08320	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
CL176_08330	ENOG4105K59	histidine triad (HIT) protein
CL176_08360	ENOG4106D4I	domain protein
CL176_08365	ENOG4107RFY	SbcCD D subunit
CL176_08370	ENOG4105WZB	UPF0342 protein
CL176_08375	ENOG4105BZ4	penicillin-binding protein
CL176_08380	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
CL176_08390	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
CL176_08395	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CL176_08405	ENOG4108UYE	Lactoylglutathione lyase
CL176_08410	ENOG4105KG3	cytidine deaminase
CL176_08430	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
CL176_08440	ENOG4105CDY	transcriptional regulatory protein
CL176_08445	ENOG4108RAV	Conserved protein
CL176_08455	ENOG4105C02	permease
CL176_08460	ENOG4105E5Q	amino acid AbC transporter
CL176_08465	ENOG4105CDA	abc transporter atp-binding protein
CL176_08470	ENOG4108VXD	carboxy-peptidase
CL176_08480	ENOG4105CDW	Resistance protein
CL176_08500	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
CL176_08505	ENOG4105XYU	peptidase (U32 family)
CL176_08510	ENOG4105CFP	Peptidase U32
CL176_08540	ENOG4105CVG	Homoserine O-transsuccinylase
CL176_08545	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
CL176_08565	ENOG4105CA9	Pyruvate kinase
CL176_08570	ENOG4105CDA	abc transporter atp-binding protein
CL176_08575	ENOG4105E5Q	amino acid AbC transporter
CL176_08580	ENOG4105DIW	FeS assembly protein SUFB
CL176_08585	ENOG4105C7B	Threonine dehydratase
CL176_08590	ENOG4105KME	endoribonuclease L-psp
CL176_08595	ENOG4105VG1	fes assembly suf system protein
CL176_08605	ENOG4105C7K	acetolactate synthase
CL176_08610	ENOG4108ZP8	Acetolactate synthase small subunit
CL176_08615	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
CL176_08620	ENOG4105DKW	ABC transporter
CL176_08640	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
CL176_08670	ENOG4105DPN	Oligoendopeptidase f
CL176_08675	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
CL176_08705	ENOG4108TFM	Kinase, PfkB family
CL176_08710	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
CL176_08715	ENOG4108KD5	ADP-ribosylation crystallin J1
CL176_08730	ENOG4105F3R	pts system mannose fructose sorbose family iid
CL176_08735	ENOG4105ETZ	PTS System
CL176_08740	ENOG4108EQA	pts system
CL176_08750	ENOG4108YZT	Adenosylcobinamide kinase
CL176_08755	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CL176_08760	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
CL176_08780	ENOG4108IJ2	phosphate acetyltransferase
CL176_08785	ENOG4107RWI	ethanolamine utilization protein eutJ
CL176_08790	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CL176_08795	ENOG4105ENY	Ethanolamine utilization protein eutH
CL176_08810	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
CL176_08820	ENOG4105KNY	Microcompartments protein
CL176_08825	ENOG4108EKI	Dehydrogenase
CL176_08835	ENOG4106D67	ethanolamine utilization protein
CL176_08840	ENOG4107FQ9	ethanolamine ammonia-lyase
CL176_08845	ENOG4105CPD	ethanolamine ammonia-lyase
CL176_08850	ENOG4105DYY	Reactivating factor for ethanolamine ammonia lyase
CL176_08870	ENOG4108WBT	adenosyltransferase
CL176_08875	ENOG4106S4J	ethanolamine utilization protein EutP
CL176_08880	ENOG4105M3W	utilization protein
CL176_08890	ENOG4105E5H	Transposase
CL176_08900	ENOG4105E0A	ABC, transporter
CL176_08905	ENOG4105EHG	Permease protein
CL176_08915	ENOG4108DBC	nitroreductase
CL176_08930	ENOG4105D52	delta-aminolevulinic acid dehydratase
CL176_08940	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
CL176_08945	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CL176_08950	ENOG4108WBT	adenosyltransferase
CL176_08965	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CL176_08970	ENOG4105QUC	reductase
CL176_08975	ENOG4105E4R	Precorrin-3B C17-methyltransferase
CL176_08980	ENOG4108P62	biosynthesis protein (CbiG)
CL176_08985	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
CL176_08990	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
CL176_08995	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
CL176_09000	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
CL176_09005	ENOG41081F0	Precorrin-8x methylmutase
CL176_09010	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CL176_09015	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
CL176_09025	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
CL176_09040	ENOG4105E0A	ABC, transporter
CL176_09045	ENOG4105EHG	Permease protein
CL176_09080	ENOG4105DEN	Luciferase family
CL176_09095	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
CL176_09120	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
CL176_09125	ENOG4105CSA	Coproporphyrinogen iii oxidase
CL176_09145	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
CL176_09170	ENOG4107V0Z	fmn reductase
CL176_09195	ENOG4107RGD	Major Facilitator superfamily
CL176_09200	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
CL176_09205	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
CL176_09245	ENOG4105F8V	Hydrolase, tatD family
CL176_09250	ENOG4105CUZ	uba thif-type nad fad binding protein
CL176_09260	ENOG4105EEI	dihydropteroate synthase
CL176_09265	ENOG4105EUJ	GTP cyclohydrolase i
CL176_09270	ENOG4105KFW	domain protein
CL176_09275	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CL176_09285	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CL176_09290	ENOG4107RCQ	(CBS) domain
CL176_09295	ENOG4105D01	(LipO)protein
CL176_09300	ENOG4108IJ9	(ABC) transporter
CL176_09305	ENOG41063TF	transcriptional regulator (AraC
CL176_09315	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
CL176_09320	ENOG4105DRS	transport system, permease
CL176_09340	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
CL176_09345	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
CL176_09350	ENOG4105CMR	udp-glucose 4-epimerase
CL176_09355	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
CL176_09380	ENOG4105DQ6	Transposase
CL176_09390	ENOG4105CMR	udp-glucose 4-epimerase
CL176_09400	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
CL176_09410	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
CL176_09415	ENOG4108K2B	transcriptional regulator
CL176_09420	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CL176_09430	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
CL176_09455	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
CL176_09460	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
CL176_09470	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
CL176_09485	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
CL176_09490	ENOG4106M28	alanine racemase domain protein
CL176_09500	ENOG4105C59	p-type ATPase
CL176_09520	ENOG4105D01	(LipO)protein
CL176_09565	ENOG4107QTH	restriction modification system DNA specificity domain
CL176_09575	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
CL176_09595	ENOG4108Z6Z	Transcriptional regulator
CL176_09610	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
CL176_09615	ENOG4108HCJ	Hydrolase
CL176_09635	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
CL176_09655	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
CL176_09695	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CL176_09730	ENOG4105CB5	ATP-dependent DNA helicase recG
CL176_09770	ENOG4105W2C	Glycosyl transferase
CL176_09790	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CL176_09880	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CL176_09890	ENOG4108XTP	Transcriptional regulator
CL176_09920	ENOG4105MU5	relaxase mobilization nuclease domain protein
CL176_09930	ENOG4105WT3	Transcriptional regulator
CL176_09935	ENOG4105WT3	Transcriptional regulator
CL176_09950	ENOG4108IUW	ABC transporter
CL176_09980	ENOG4106QJ6	Integrase catalytic subunit
CL176_10025	ENOG4105K4H	Nlp p60 protein
CL176_10055	ENOG4108J59	Extracellular solute-binding protein, family 5
CL176_10060	ENOG4108K88	Membrane
CL176_10065	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CL176_10075	ENOG4108CHM	Preferentially cleaves peptide bonds on the carboxyl- terminal side of aspartate and glutamate. Along with other extracellular proteases it is involved in colonization and infection of human tissues. Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB. It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells. May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG, IgA and IgM. May be involved in the stability of secreted lipases
CL176_10080	ENOG4105CSR	polyphosphate kinase 2
CL176_10085	ENOG4105EI2	Pseudouridine synthase
CL176_10090	ENOG4105CH6	catalase
CL176_10095	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
CL176_10100	ENOG4105ERH	Fumarylacetoacetate hydrolase
CL176_10105	ENOG4105ERH	Fumarylacetoacetate hydrolase
CL176_10130	ENOG4108UW5	maltose o-acetyltransferase
CL176_10145	ENOG4105CHM	Aminotransferase
CL176_10155	ENOG4108HCJ	Hydrolase
CL176_10170	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CL176_10180	ENOG4105E0A	ABC, transporter
CL176_10185	ENOG4105EHG	Permease protein
CL176_10190	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CL176_10330	ENOG4105DVF	Cytosine-specific methyltransferase
CL176_10355	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CL176_10360	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
CL176_10370	ENOG4108HCJ	Hydrolase
CL176_10380	ENOG4105FGM	Fructosamine kinase
CL176_10425	ENOG4108UMN	azlc family
CL176_10430	ENOG4105KMT	branched-chain amino acid
CL176_10435	ENOG410667J	hydrolase
CL176_10440	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CL176_10460	ENOG4105DFD	Na H antiporter
CL176_10465	ENOG4105CPC	Aldo Keto reductase
CL176_10475	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
CL176_10495	ENOG4106N3A	copper homeostasis protein cutc
CL176_10500	ENOG4105CE4	GlcNAc 6-P deacetylase
CL176_10505	ENOG4105K78	MarR family Transcriptional regulator
CL176_10510	ENOG4105C75	arginyL-tRNA synthetase
CL176_10520	ENOG4108Z6X	(sortase) family
CL176_10530	ENOG4105VAW	lrga family
CL176_10535	ENOG41067MG	lrgb family
CL176_10545	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
CL176_10550	ENOG4105D6E	homoserine dehydrogenase
CL176_10555	ENOG4105CFH	Aspartokinase
CL176_10560	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
CL176_10565	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CL176_10570	ENOG4105KJF	protein tyrosine phosphatase
CL176_10575	ENOG4108Z0Z	intracellular protease Pfpi family
CL176_10590	ENOG4105DIH	basic membrane
CL176_10605	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
CL176_10610	ENOG4108JQ1	Dehydrogenase
CL176_10615	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
CL176_10630	ENOG4108IUM	Glycogen debranching enzyme
CL176_10640	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
CL176_10655	ENOG4105D6U	Sodium Glutamate Symporter
CL176_10660	ENOG4105CJ1	ABC, transporter
CL176_10705	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CL176_10710	ENOG4105CS9	pantothenic acid kinase
CL176_10715	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
CL176_10730	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
CL176_10745	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
CL176_10765	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CL176_10770	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
CL176_10780	ENOG4105CKK	Glycosyl transferase, family 2
CL176_10795	ENOG4105D4A	Cell wall formation (By similarity)
CL176_10815	ENOG4108IJ2	phosphate acetyltransferase
CL176_10820	ENOG4105NA0	Transcriptional regulator
CL176_10845	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
CL176_10850	ENOG4105C5H	ABC transporter
CL176_10855	ENOG4105CDY	transcriptional regulatory protein
CL176_10860	ENOG4108V06	Glutathione peroxidase
CL176_10870	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CL176_10875	ENOG4108IV0	ABC, transporter
CL176_10880	ENOG4105C0Z	ABC transporter
CL176_10885	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
CL176_10890	ENOG4105C32	Amino acid ABC transporter (Permease)
CL176_10900	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CL176_10925	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CL176_10940	ENOG4105CP9	extracellular ligand-binding receptor
CL176_10955	ENOG4105DVE	abc transporter atp-binding protein
CL176_10965	ENOG4105IJJ	transcriptional regulator, crp fnr family
CL176_10975	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CL176_10985	ENOG4105FDK	ABC transporter
CL176_10990	ENOG4105DSE	periplasmic solute binding protein
CL176_11010	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CL176_11020	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
CL176_11025	ENOG4105CAH	Chromate
CL176_11055	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
CL176_11065	ENOG4108JJB	ABC transporter
CL176_11070	ENOG4108JJB	ABC transporter
CL176_11080	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CL176_11085	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
CL176_11090	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CL176_11095	ENOG41067V7	50S ribosomal protein L36
CL176_11100	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CL176_11110	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
CL176_11115	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CL176_11120	ENOG4105VPB	50S ribosomal protein L30
CL176_11125	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CL176_11130	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
CL176_11135	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CL176_11140	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CL176_11145	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CL176_11150	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CL176_11165	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
CL176_11170	ENOG41082SA	50s ribosomal protein l29
CL176_11175	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CL176_11185	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CL176_11190	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CL176_11195	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CL176_11200	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
CL176_11205	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CL176_11210	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CL176_11220	ENOG4107YX5	Pfam:DUF548
CL176_11230	ENOG4105CQC	Prephenate dehydratase
CL176_11240	ENOG4105E5Q	amino acid AbC transporter
CL176_11250	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CL176_11255	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CL176_11260	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CL176_11265	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
CL176_11270	ENOG4105RHA	ABC transporter, permease
CL176_11275	ENOG4108IUX	(ABC) transporter
CL176_11285	ENOG4105C6T	cysteine synthase
CL176_11290	ENOG4105D7W	serine acetyltransferase
CL176_11295	ENOG4105CRK	lysyL-tRNA synthetase
CL176_11300	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
CL176_11310	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
CL176_11315	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CL176_11320	ENOG4105EFI	regulatoR
CL176_11325	ENOG4105BZU	Histidine kinase
CL176_11330	ENOG41060GV	RNA binding s1 domain protein
CL176_11340	ENOG41082I2	s4 domain protein
CL176_11345	ENOG4108JA2	transcriptioN-repair coupling factor
CL176_11350	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
CL176_11355	ENOG4105W42	Veg protein
CL176_11365	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
CL176_11370	ENOG4105F8V	Hydrolase, tatD family
CL176_11375	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CL176_11395	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
CL176_11400	ENOG4105BZU	Histidine kinase
CL176_11405	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CL176_11410	ENOG4108UUM	single-stranded DNA-binding protein
CL176_11415	ENOG4105CIE	May be required for sporulation (By similarity)
CL176_11425	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
CL176_11435	ENOG4105C3M	thioredoxin reductase
CL176_11440	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CL176_11445	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CL176_11450	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
CL176_11455	ENOG41067S9	phage shock protein C, PspC
CL176_11465	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CL176_11470	ENOG4107S17	Phosphate-binding protein
CL176_11475	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
CL176_11480	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CL176_11485	ENOG4105E2Z	phosphate ABC transporter (Permease
CL176_11490	ENOG4105C8U	phosphate abc transporter
CL176_11495	ENOG4105BZU	Histidine kinase
CL176_11500	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CL176_11505	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
CL176_11510	ENOG4105CAK	Cell division ATP-binding protein ftsE
CL176_11515	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
CL176_11520	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CL176_11545	ENOG4105CBD	Diacylglycerol kinase
CL176_11550	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
CL176_11565	ENOG4108RVA	ribokinase
CL176_11570	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
CL176_11575	ENOG4105EPR	degv family
CL176_11580	ENOG4105ESV	Glycosyl transferase, family 4
CL176_11590	ENOG4105DAP	Nicotinate phosphoribosyltransferase
CL176_11605	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CL176_11615	ENOG4105DFT	pur operon repressor
CL176_11620	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
CL176_11625	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
CL176_11630	ENOG4105ETD	TRANSCRIPTIONal
CL176_11635	ENOG4105CTS	PTS system mannitol-specific
CL176_11645	ENOG4105FDK	ABC transporter
CL176_11650	ENOG4108U5N	UPF0316 protein
CL176_11655	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CL176_11675	ENOG4105C7J	ABC transporter, permease
CL176_11710	ENOG4105BZ1	(ABC) transporter
CL176_11725	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
CL176_11755	ENOG4105HFT	AraC family transcriptional regulator
CL176_11760	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
CL176_11770	ENOG4105C8B	TIGR00159 family
CL176_11775	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CL176_11790	ENOG4105VKD	bioY protein
CL176_11795	ENOG4105CV8	reductase
CL176_11800	ENOG4105DM4	PTS System
CL176_11805	ENOG4105DE4	1-phosphofructokinase
CL176_11810	ENOG4105E98	transcriptional regulator DeoR family
CL176_11815	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CL176_11860	ENOG4106A3R	peptidase
CL176_11865	ENOG4105E8R	UPF0173 metal-dependent hydrolase
CL176_11875	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CL176_11880	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CL176_11885	ENOG4107Y49	methyltransferase
CL176_11890	ENOG410667J	hydrolase
CL176_11900	ENOG4108VZM	50s ribosomal protein L10
CL176_11905	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CL176_11910	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
CL176_11930	ENOG4105I7V	membrAne
CL176_11945	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
CL176_11950	ENOG410683Z	Preprotein translocase SecE subunit
CL176_11955	ENOG4107FTN	50S ribosomal protein L33
CL176_11965	ENOG4105M0M	Tetracycline resistance protein
CL176_11970	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CL176_11975	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CL176_11980	ENOG4105C8N	cysteinyl-tRNA synthetase
CL176_11985	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CL176_11990	ENOG4105CTP	PilT protein domain protein
CL176_11995	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
CL176_12000	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
CL176_12010	ENOG4105C5F	glutamine synthetase
CL176_12020	ENOG4105CDU	Replicative dna helicase
CL176_12025	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CL176_12035	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CL176_12040	ENOG4108UUM	single-stranded DNA-binding protein
CL176_12045	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
CL176_12050	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CL176_12055	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)