locus-tag	class	description
JDW14_00010	COG0592	DNA-directed DNA polymerase activity
JDW14_00015	COG1876	peptidase activity
JDW14_00020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JDW14_00025	COG0785	Cytochrome C biogenesis protein
JDW14_00030	COG2501	S4 domain
JDW14_00035	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JDW14_00040	COG0187	DNA topoisomerase II activity
JDW14_00060	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JDW14_00070	COG0359	binds to the 23S rRNA
JDW14_00075	COG0305	Participates in initiation and elongation during chromosome replication
JDW14_00080	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JDW14_00085	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JDW14_00095	COG0789	Transcriptional regulator
JDW14_00110	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JDW14_00115	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JDW14_00125	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JDW14_00130	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JDW14_00135	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JDW14_00140	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JDW14_00145	COG1307	EDD domain protein, DegV family
JDW14_00150	COG1739	Uncharacterized protein family UPF0029
JDW14_00155	COG1307	EDD domain protein, DegV family
JDW14_00160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JDW14_00165	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JDW14_00170	COG1040	competence protein
JDW14_00185	COG0653	protein targeting
JDW14_00195	COG2884	Cell division ATP-binding protein ftsE
JDW14_00200	COG2177	Part of the ABC transporter FtsEX involved in
JDW14_00205	COG3842	ATPase activity
JDW14_00210	COG0756	dUTP diphosphatase activity
JDW14_00220	COG4956	integral membrane protein (PIN domain superfamily)
JDW14_00225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JDW14_00235	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JDW14_00240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JDW14_00245	COG3688	RNA-binding protein containing a PIN domain
JDW14_00260	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JDW14_00265	COG0250	Participates in transcription elongation, termination and antitermination
JDW14_00270	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JDW14_00275	COG0081	regulation of translation
JDW14_00280	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JDW14_00285	COG0222	ribosome binding
JDW14_00290	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
JDW14_00300	COG5002	protein histidine kinase activity
JDW14_00310	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JDW14_00350	COG2855	membrane
JDW14_00365	COG2321	neutral zinc metallopeptidase
JDW14_00370	COG0726	polysaccharide deacetylase
JDW14_00375	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JDW14_00390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JDW14_00410	COG4120	Belongs to the binding-protein-dependent transport system permease family
JDW14_00415	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JDW14_00450	COG0410	ABC transporter
JDW14_00455	COG0517	IMP dehydrogenase activity
JDW14_00455	COG0516	GMP reductase activity
JDW14_00465	COG2197	response regulator
JDW14_00470	COG1131	(ABC) transporter
JDW14_00485	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JDW14_00490	COG0049	tRNA binding
JDW14_00495	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JDW14_00500	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JDW14_00505	COG0668	transmembrane transport
JDW14_00510	COG0051	transcription antitermination factor activity, RNA binding
JDW14_00515	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JDW14_00525	COG0089	rRNA binding
JDW14_00530	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JDW14_00545	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JDW14_00560	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JDW14_00565	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JDW14_00575	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JDW14_00585	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JDW14_00595	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JDW14_00600	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JDW14_00605	COG1841	ribosomal large subunit assembly
JDW14_00610	COG0200	Binds to the 23S rRNA
JDW14_00620	COG0563	adenylate kinase activity
JDW14_00630	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JDW14_00635	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JDW14_00640	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JDW14_00645	COG0202	RNA polymerase activity
JDW14_00650	COG0203	ribosomal protein L17
JDW14_00660	COG1122	ATPase activity
JDW14_00665	COG1122	ATPase activity
JDW14_00680	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JDW14_00685	COG0371	Dehydrogenase
JDW14_00690	COG0385	Bile acid
JDW14_00695	COG0656	L-ascorbic acid biosynthetic process
JDW14_00710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JDW14_00715	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JDW14_00720	COG1116	anion transmembrane transporter activity
JDW14_00735	COG1132	(ABC) transporter
JDW14_00745	COG1268	BioY protein
JDW14_00765	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JDW14_00780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JDW14_00785	COG0500	methyltransferase
JDW14_00795	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JDW14_00800	COG1253	flavin adenine dinucleotide binding
JDW14_00805	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JDW14_00815	COG1121	(ABC) transporter
JDW14_00820	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JDW14_00835	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JDW14_00840	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JDW14_00845	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JDW14_00850	COG4122	O-methyltransferase activity
JDW14_00855	COG1132	(ABC) transporter
JDW14_00875	COG0561	phosphatase activity
JDW14_00885	COG0745	RESPONSE REGULATOR receiver
JDW14_00890	COG5002	protein histidine kinase activity
JDW14_00905	COG1214	PFAM Peptidase M22, glycoprotease
JDW14_00910	COG0456	acetyltransferase
JDW14_00920	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JDW14_00925	COG4166	transmembrane transport
JDW14_00930	COG0601	transmembrane transport
JDW14_00935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JDW14_00940	COG0444	Belongs to the ABC transporter superfamily
JDW14_00945	COG4608	Belongs to the ABC transporter superfamily
JDW14_00950	COG3620	sequence-specific DNA binding
JDW14_00955	COG1725	Transcriptional regulator
JDW14_00960	COG1131	(ABC) transporter
JDW14_00975	COG1316	TRANSCRIPTIONal
JDW14_00980	COG1215	transferase activity, transferring glycosyl groups
JDW14_00990	COG0438	transferase activity, transferring glycosyl groups
JDW14_01015	COG1316	TRANSCRIPTIONal
JDW14_01030	COG0562	UDP-galactopyranose mutase
JDW14_01080	COG1051	belongs to the nudix hydrolase family
JDW14_01090	COG0438	transferase activity, transferring glycosyl groups
JDW14_01095	COG0516	GMP reductase activity
JDW14_01100	COG0488	(ABC) transporter
JDW14_01120	COG0494	nUDIX hydrolase
JDW14_01125	COG1780	Probably involved in ribonucleotide reductase function
JDW14_01130	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JDW14_01140	COG1301	dicarboxylic acid transport
JDW14_01155	COG1396	sequence-specific DNA binding
JDW14_01175	COG0625	glutathione transferase activity
JDW14_01185	COG1187	pseudouridine synthase activity
JDW14_01205	COG1269	ATP hydrolysis coupled proton transport
JDW14_01210	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JDW14_01230	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
JDW14_01235	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
JDW14_01240	COG1394	ATPase activity, coupled to movement of substances
JDW14_01245	COG1837	Belongs to the UPF0109 family
JDW14_01250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JDW14_01255	COG1321	iron dependent repressor
JDW14_01255	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JDW14_01260	COG1121	(ABC) transporter
JDW14_01265	COG0803	Belongs to the bacterial solute-binding protein 9 family
JDW14_01275	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JDW14_01280	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JDW14_01290	COG0167	dihydroorotate dehydrogenase activity
JDW14_01295	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JDW14_01305	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JDW14_01305	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JDW14_01310	COG0631	protein serine/threonine phosphatase activity
JDW14_01315	COG0515	serine threonine protein kinase
JDW14_01315	COG2815	serine threonine protein kinase
JDW14_01320	COG1162	GTPase activity
JDW14_01325	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JDW14_01330	COG1564	THIamine pyrophosphokinase
JDW14_01335	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JDW14_01340	COG1302	Protein conserved in bacteria
JDW14_01345	COG1461	Dihydroxyacetone kinase
JDW14_01350	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JDW14_01355	COG0416	fatty acid biosynthetic process
JDW14_01360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JDW14_01370	COG4608	Belongs to the ABC transporter superfamily
JDW14_01375	COG0601	transmembrane transport
JDW14_01380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JDW14_01385	COG1546	Belongs to the CinA family
JDW14_01385	COG1058	Belongs to the CinA family
JDW14_01395	COG3853	Toxic anion resistance protein (TelA)
JDW14_01400	COG1349	DNA-binding transcription factor activity
JDW14_01405	COG0235	Class ii aldolase
JDW14_01415	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JDW14_01420	COG1447	Phosphotransferase system cellobiose-specific component IIA
JDW14_01425	COG1129	ABC transporter
JDW14_01430	COG1172	Belongs to the binding-protein-dependent transport system permease family
JDW14_01440	COG1070	Carbohydrate kinase
JDW14_01445	COG4154	Belongs to the RbsD FucU family
JDW14_01450	COG1454	alcohol dehydrogenase
JDW14_01455	COG0803	Belongs to the bacterial solute-binding protein 9 family
JDW14_01455	COG3443	Belongs to the bacterial solute-binding protein 9 family
JDW14_01460	COG1309	transcriptional regulator
JDW14_01465	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JDW14_01485	COG1116	anion transmembrane transporter activity
JDW14_01490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JDW14_01505	COG1609	Transcriptional regulator
JDW14_01515	COG1621	beta-fructofuranosidase activity
JDW14_01535	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JDW14_01565	COG1132	(ABC) transporter
JDW14_01580	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JDW14_01585	COG3715	PTS system
JDW14_01590	COG3716	PTS system mannose fructose sorbose family IID component
JDW14_01595	COG1917	Cupin 2, conserved barrel domain protein
JDW14_01595	COG4977	sequence-specific DNA binding
JDW14_01600	COG1653	transport
JDW14_01605	COG1175	transmembrane transport
JDW14_01610	COG0395	ABC-type sugar transport system, permease component
JDW14_01615	COG5426	von Willebrand factor, type A
JDW14_01630	COG2222	sugar isomerase
JDW14_01640	COG3684	Belongs to the aldolase LacD family
JDW14_01645	COG0386	Belongs to the glutathione peroxidase family
JDW14_01650	COG0217	transcriptional regulatory protein
JDW14_01655	COG1388	LysM domain
JDW14_01655	COG1705	Flagellar rod assembly protein muramidase FlgJ
JDW14_01665	COG0556	nucleotide-excision repair
JDW14_01670	COG2755	lipolytic protein G-D-S-L family
JDW14_01670	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JDW14_01675	COG0494	nUDIX hydrolase
JDW14_01680	COG2816	NAD+ diphosphatase activity
JDW14_01700	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JDW14_01705	COG1185	polyribonucleotide nucleotidyltransferase activity
JDW14_01710	COG0180	Tryptophanyl-tRNA synthetase
JDW14_01715	COG1393	Belongs to the ArsC family
JDW14_01720	COG4862	establishment of competence for transformation
JDW14_01730	COG1164	Oligoendopeptidase f
JDW14_01760	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JDW14_01765	COG0510	thiamine kinase activity
JDW14_01775	COG1609	Transcriptional regulator
JDW14_01785	COG0235	Class ii aldolase
JDW14_01790	COG2160	L-arabinose isomerase activity
JDW14_01795	COG3507	Belongs to the glycosyl hydrolase 43 family
JDW14_01820	COG2211	Major facilitator Superfamily
JDW14_01825	COG3250	beta-galactosidase activity
JDW14_01830	COG1363	Peptidase, m42
JDW14_01835	COG0072	phenylalanine-tRNA ligase activity
JDW14_01845	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JDW14_01850	COG0583	DNA-binding transcription factor activity
JDW14_01855	COG0133	tryptophan synthase activity
JDW14_01870	COG0628	permease
JDW14_01900	COG1522	sequence-specific DNA binding
JDW14_01905	COG0436	Aminotransferase
JDW14_01910	COG1164	Oligoendopeptidase f
JDW14_01925	COG1132	(ABC) transporter
JDW14_01935	COG0228	four-way junction DNA binding
JDW14_01940	COG3590	peptidase
JDW14_01945	COG1979	alcohol dehydrogenase
JDW14_01950	COG0534	Mate efflux family protein
JDW14_01955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JDW14_01960	COG2261	transglycosylase associated protein
JDW14_01975	COG4470	Protein conserved in bacteria
JDW14_01980	COG0647	UMP catabolic process
JDW14_01990	COG0673	inositol 2-dehydrogenase activity
JDW14_01995	COG0513	Belongs to the DEAD box helicase family
JDW14_02000	COG0745	RESPONSE REGULATOR receiver
JDW14_02005	COG5002	protein histidine kinase activity
JDW14_02015	COG1609	Transcriptional regulator
JDW14_02020	COG4209	transmembrane transport
JDW14_02025	COG0395	ABC-type sugar transport system, permease component
JDW14_02030	COG1653	transport
JDW14_02035	COG1621	beta-fructofuranosidase activity
JDW14_02040	COG1940	carbohydrate kinase activity
JDW14_02045	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JDW14_02055	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JDW14_02060	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JDW14_02065	COG0297	glycogen (starch) synthase activity
JDW14_02070	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JDW14_02075	COG1466	dna polymerase III delta subunit
JDW14_02085	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JDW14_02130	COG1435	thymidine kinase activity
JDW14_02135	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JDW14_02140	COG2890	protein-(glutamine-N5) methyltransferase activity
JDW14_02145	COG0009	L-threonylcarbamoyladenylate synthase
JDW14_02150	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JDW14_02160	COG1131	(ABC) transporter
JDW14_02165	COG0842	Transport permease protein
JDW14_02175	COG2197	response regulator
JDW14_02180	COG0183	Belongs to the thiolase family
JDW14_02185	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JDW14_02205	COG0527	aspartate kinase activity
JDW14_02210	COG0460	homoserine dehydrogenase
JDW14_02215	COG0083	homoserine kinase activity
JDW14_02225	COG0702	epimerase
JDW14_02230	COG1959	2 iron, 2 sulfur cluster binding
JDW14_02235	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JDW14_02265	COG1285	pathogenesis
JDW14_02285	COG0072	phenylalanine-tRNA ligase activity
JDW14_02285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JDW14_02300	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JDW14_02305	COG2217	Heavy metal translocating P-type atpase
JDW14_02310	COG1968	undecaprenyl-diphosphatase activity
JDW14_02315	COG2190	(PTS) system
JDW14_02315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JDW14_02315	COG1263	PTS System
JDW14_02330	COG0525	valine-tRNA ligase activity
JDW14_02340	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JDW14_02345	COG4605	iron ion homeostasis
JDW14_02350	COG4604	ABC transporter, ATP-binding protein
JDW14_02355	COG4607	ABC-type enterochelin transport system periplasmic component
JDW14_02360	COG0826	peptidase U32
JDW14_02365	COG0826	peptidase U32
JDW14_02375	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JDW14_02390	COG1193	negative regulation of DNA recombination
JDW14_02405	COG2252	PERMEase
JDW14_02410	COG0588	phosphoglycerate mutase activity
JDW14_02415	COG1295	ribonuclease BN
JDW14_02420	COG0772	Belongs to the SEDS family
JDW14_02455	COG1705	Flagellar rod assembly protein muramidase FlgJ
JDW14_02455	COG1388	LysM domain
JDW14_02485	COG0495	leucyl-tRNA aminoacylation
JDW14_02490	COG2244	polysaccharide biosynthetic process
JDW14_02495	COG1187	pseudouridine synthase activity
JDW14_02500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JDW14_02505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JDW14_02525	COG1609	Transcriptional regulator
JDW14_02530	COG1596	polysaccharide export
JDW14_02530	COG1555	photosystem II stabilization
JDW14_02535	COG0658	competence protein
JDW14_02535	COG2333	competence protein COMEC
JDW14_02540	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JDW14_02545	COG1104	cysteine desulfurase activity
JDW14_02560	COG0708	Exodeoxyribonuclease III
JDW14_02565	COG1523	belongs to the glycosyl hydrolase 13 family
JDW14_02575	COG1704	LemA family
JDW14_02590	COG1181	Belongs to the D-alanine--D-alanine ligase family
JDW14_02595	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JDW14_02600	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
JDW14_02610	COG3639	organic phosphonate transmembrane transporter activity
JDW14_02615	COG0018	arginyl-trna synthetase
JDW14_02620	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JDW14_02625	COG2011	ABC-type metal ion transport system permease component
JDW14_02630	COG1464	Belongs to the NlpA lipoprotein family
JDW14_02645	COG0561	phosphatase activity
JDW14_02650	COG2813	Specifically methylates the guanine in position
JDW14_02675	COG1215	transferase activity, transferring glycosyl groups
JDW14_02690	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JDW14_02695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JDW14_02715	COG1983	PspC domain protein
JDW14_02720	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JDW14_02730	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JDW14_02740	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JDW14_02740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JDW14_02745	COG0084	hydrolase, TatD family'
JDW14_02750	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JDW14_02755	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JDW14_02760	COG4555	ABC transporter
JDW14_02800	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JDW14_02805	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JDW14_02820	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
JDW14_02825	COG3052	prosthetic group binding
JDW14_02860	COG0511	ligase activity, forming carbon-carbon bonds
JDW14_02865	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
JDW14_02870	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JDW14_02880	COG0024	Methionine aminopeptidase
JDW14_02895	COG0494	nUDIX hydrolase
JDW14_02905	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JDW14_02910	COG0058	SHG alpha-glucan phosphorylase activity
JDW14_02915	COG1640	4-alpha-glucanotransferase
JDW14_02920	COG1609	Transcriptional regulator
JDW14_02925	COG0356	it plays a direct role in the translocation of protons across the membrane
JDW14_02935	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JDW14_02945	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JDW14_02950	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JDW14_02955	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JDW14_03130	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JDW14_03210	COG5484	DNA packaging
JDW14_03210	COG3728	DNA packaging
JDW14_03215	COG1783	phage Terminase large subunit
JDW14_03355	COG1705	Flagellar rod assembly protein muramidase FlgJ
JDW14_03380	COG3969	phosphoadenosine phosphosulfate
JDW14_03385	COG1475	DNA binding
JDW14_03410	COG4224	UPF0291 protein
JDW14_03415	COG3763	UPF0154 protein
JDW14_03420	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JDW14_03425	COG1045	serine acetyltransferase
JDW14_03440	COG0537	adenosine 5'-monophosphoramidase activity
JDW14_03450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JDW14_03455	COG0513	Belongs to the DEAD box helicase family
JDW14_03460	COG0750	zinc metalloprotease
JDW14_03465	COG2176	DNA-directed DNA polymerase activity
JDW14_03470	COG4493	Belongs to the UPF0637 family
JDW14_03475	COG4476	Belongs to the UPF0223 family
JDW14_03480	COG0483	inositol monophosphate 1-phosphatase activity
JDW14_03485	COG1217	gtp-binding protein TYPA
JDW14_03495	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JDW14_03520	COG2001	Belongs to the MraZ family
JDW14_03535	COG0768	penicillin binding
JDW14_03550	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JDW14_03555	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JDW14_03560	COG0849	cell division
JDW14_03570	COG3842	ATPase activity
JDW14_03580	COG1177	transmembrane transport
JDW14_03585	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JDW14_03595	COG0772	Belongs to the SEDS family
JDW14_03600	COG4471	UPF0298 protein
JDW14_03605	COG0742	ribosomal rna small subunit methyltransferase
JDW14_03610	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JDW14_03615	COG1278	Cold shock
JDW14_03620	COG2384	SAM-dependent methyltransferase
JDW14_03625	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JDW14_03630	COG2195	Cleaves the N-terminal amino acid of tripeptides
JDW14_03640	COG1744	ABC transporter substrate-binding protein PnrA-like
JDW14_03645	COG3845	ABC transporter
JDW14_03650	COG4603	Belongs to the binding-protein-dependent transport system permease family
JDW14_03655	COG1079	Belongs to the binding-protein-dependent transport system permease family
JDW14_03680	COG0745	RESPONSE REGULATOR receiver
JDW14_03685	COG5002	protein histidine kinase activity
JDW14_03705	COG0534	Mate efflux family protein
JDW14_03740	COG0251	oxidation-reduction process
JDW14_03775	COG1426	Protein conserved in bacteria
JDW14_03780	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JDW14_03785	COG0542	response to heat
JDW14_03790	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JDW14_03795	COG1705	Flagellar rod assembly protein muramidase FlgJ
JDW14_03795	COG1388	LysM domain
JDW14_03800	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JDW14_03820	COG1028	Short-chain dehydrogenase reductase Sdr
JDW14_03825	COG4708	membrane
JDW14_03835	COG1077	Cell shape determining protein MreB Mrl
JDW14_03850	COG0735	belongs to the Fur family
JDW14_03860	COG2302	S4 RNA-binding domain
JDW14_03865	COG3599	regulation of cell shape
JDW14_03870	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JDW14_03875	COG4545	Glutaredoxin-related protein
JDW14_03880	COG0295	cytidine deaminase activity
JDW14_03885	COG0346	lactoylglutathione lyase activity
JDW14_03895	COG0531	amino acid
JDW14_03905	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JDW14_03910	COG0622	Phosphoesterase
JDW14_03935	COG1252	NADH dehydrogenase
JDW14_03945	COG4939	FMN-binding domain protein
JDW14_03980	COG0587	DNA-directed DNA polymerase activity
JDW14_03985	COG0205	6-phosphofructokinase activity
JDW14_03995	COG2239	Acts as a magnesium transporter
JDW14_04025	COG0481	GTPase activity
JDW14_04030	COG0673	inositol 2-dehydrogenase activity
JDW14_04035	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JDW14_04040	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JDW14_04045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JDW14_04065	COG2824	Alkylphosphonate utilization operon protein PhnA
JDW14_04070	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JDW14_04085	COG2755	lipolytic protein G-D-S-L family
JDW14_04085	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JDW14_04110	COG2116	formate transmembrane transporter activity
JDW14_04115	COG4166	transmembrane transport
JDW14_04120	COG3118	belongs to the thioredoxin family
JDW14_04135	COG4864	UPF0365 protein
JDW14_04145	COG1283	sodium-dependent phosphate transmembrane transporter activity
JDW14_04150	COG0671	phosphoesterase, PA-phosphatase related
JDW14_04160	COG0765	amino acid transport
JDW14_04165	COG1126	abc transporter atp-binding protein
JDW14_04180	COG0052	Belongs to the universal ribosomal protein uS2 family
JDW14_04190	COG0528	UMP kinase activity
JDW14_04195	COG1573	uracil-dna glycosylase
JDW14_04205	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JDW14_04210	COG1104	cysteine desulfurase activity
JDW14_04220	COG0482	sulfurtransferase activity
JDW14_04230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JDW14_04250	COG3227	Zinc metalloprotease (Elastase)
JDW14_04260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JDW14_04265	COG0706	membrane insertase activity
JDW14_04270	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JDW14_04275	COG0084	hydrolase, TatD family'
JDW14_04280	COG1254	Belongs to the acylphosphatase family
JDW14_04285	COG1674	ftsk spoiiie
JDW14_04290	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JDW14_04295	COG0539	negative regulation of cytoplasmic translation
JDW14_04325	COG0768	penicillin binding
JDW14_04345	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JDW14_04350	COG0758	DNA mediated transformation
JDW14_04350	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JDW14_04355	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JDW14_04375	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JDW14_04380	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JDW14_04390	COG0019	diaminopimelate decarboxylase activity
JDW14_04400	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JDW14_04405	COG0463	Glycosyl transferase, family 2
JDW14_04425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JDW14_04440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JDW14_04445	COG3679	Belongs to the UPF0342 family
JDW14_04455	COG4717	serine-type aminopeptidase activity
JDW14_04460	COG3481	metal-dependent phosphohydrolase, HD sub domain
JDW14_04475	COG1131	(ABC) transporter
JDW14_04490	COG2207	Transcriptional regulator
JDW14_04500	COG4806	L-rhamnose isomerase
JDW14_04515	COG4589	Belongs to the CDS family
JDW14_04520	COG1879	ABC-type sugar transport system periplasmic component
JDW14_04535	COG0561	phosphatase activity
JDW14_04540	COG2151	metal-sulfur cluster biosynthetic enzyme
JDW14_04545	COG0204	Acyl-transferase
JDW14_04555	COG0343	queuine tRNA-ribosyltransferase activity
JDW14_04560	COG1862	Preprotein translocase
JDW14_04575	COG0779	Required for maturation of 30S ribosomal subunits
JDW14_04580	COG0195	Participates in both transcription termination and antitermination
JDW14_04585	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JDW14_04600	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JDW14_04615	COG3307	-O-antigen
JDW14_04625	COG1215	transferase activity, transferring glycosyl groups
JDW14_04630	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JDW14_04635	COG4472	Bacterial protein of unknown function (DUF965)
JDW14_04640	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JDW14_04650	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JDW14_04655	COG0572	uridine kinase
JDW14_04660	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JDW14_04670	COG4585	Histidine kinase
JDW14_04675	COG2197	response regulator
JDW14_04680	COG4841	protein insertion into membrane
JDW14_04695	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JDW14_04700	COG0745	RESPONSE REGULATOR receiver
JDW14_04705	COG5002	protein histidine kinase activity
JDW14_04715	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JDW14_04725	COG1597	lipid kinase activity
JDW14_04735	COG1196	nuclear chromosome segregation
JDW14_04740	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JDW14_04755	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JDW14_04765	COG1940	carbohydrate kinase activity
JDW14_04770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JDW14_04785	COG1293	RNA-binding protein homologous to eukaryotic snRNP
JDW14_04795	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JDW14_04820	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JDW14_04825	COG0456	acetyltransferase
JDW14_04835	COG1074	ATP-dependent DNA helicase activity
JDW14_04840	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JDW14_04845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JDW14_04845	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JDW14_04845	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JDW14_04850	COG1105	Belongs to the carbohydrate kinase PfkB family
JDW14_04855	COG1349	DNA-binding transcription factor activity
JDW14_04860	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JDW14_04865	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JDW14_04875	COG1132	(ABC) transporter
JDW14_04880	COG1132	(ABC) transporter
JDW14_04885	COG0571	ribonuclease III activity
JDW14_04895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JDW14_04905	COG0765	amino acid transport
JDW14_04925	COG1381	Involved in DNA repair and RecF pathway recombination
JDW14_04930	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JDW14_04935	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JDW14_04940	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JDW14_04950	COG1702	phosphate starvation-inducible protein PhoH
JDW14_04955	COG1610	YqeY-like protein
JDW14_04965	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JDW14_04970	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JDW14_04975	COG4974	Belongs to the 'phage' integrase family
JDW14_04985	COG2723	6-phospho-beta-galactosidase activity
JDW14_05000	COG1472	Belongs to the glycosyl hydrolase 3 family
JDW14_05005	COG2211	Major facilitator Superfamily
JDW14_05010	COG1917	Cupin 2, conserved barrel domain protein
JDW14_05010	COG4977	sequence-specific DNA binding
JDW14_05015	COG1418	mRNA catabolic process
JDW14_05020	COG1216	Glycosyl transferase, family 2
JDW14_05040	COG1388	LysM domain
JDW14_05040	COG1705	Flagellar rod assembly protein muramidase FlgJ
JDW14_05200	COG2189	Belongs to the N(4) N(6)-methyltransferase family
JDW14_05225	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JDW14_05240	COG0629	single-stranded DNA binding
JDW14_05250	COG3935	DnaD domain protein
JDW14_05255	COG3723	Recombinational DNA repair protein, rece pathway
JDW14_05260	COG5377	YqaJ viral recombinase family
JDW14_05310	COG0582	viral genome integration into host DNA
JDW14_05315	COG0335	large ribosomal subunit rRNA binding
JDW14_05320	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JDW14_05325	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JDW14_05330	COG2255	four-way junction helicase activity
JDW14_05335	COG0632	four-way junction helicase activity
JDW14_05345	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JDW14_05350	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JDW14_05355	COG1692	metallophosphoesterase
JDW14_05360	COG0673	inositol 2-dehydrogenase activity
JDW14_05365	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JDW14_05380	COG0564	pseudouridine synthase activity
JDW14_05385	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JDW14_05400	COG0552	protein localization to endoplasmic reticulum
JDW14_05405	COG0561	phosphatase activity
JDW14_05415	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JDW14_05425	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JDW14_05430	COG1482	cell wall glycoprotein biosynthetic process
JDW14_05445	COG1132	(ABC) transporter
JDW14_05450	COG1132	(ABC) transporter
JDW14_05460	COG3250	beta-galactosidase activity
JDW14_05465	COG0825	malonyl-CoA metabolic process
JDW14_05475	COG0439	Biotin carboxylase
JDW14_05480	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JDW14_05490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JDW14_05510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JDW14_05515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JDW14_05525	COG1187	pseudouridine synthase activity
JDW14_05530	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JDW14_05535	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JDW14_05550	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JDW14_05555	COG4974	Belongs to the 'phage' integrase family
JDW14_05560	COG2996	Protein conserved in bacteria
JDW14_05565	COG0514	ATP-dependent DNA helicase (RecQ)
JDW14_05575	COG0534	Mate efflux family protein
JDW14_05585	COG0322	excinuclease ABC activity
JDW14_05600	COG1028	Short-chain dehydrogenase reductase Sdr
JDW14_05605	COG0596	Alpha beta hydrolase
JDW14_05610	COG3321	synthase
JDW14_05610	COG1028	Short-chain dehydrogenase reductase Sdr
JDW14_05610	COG0604	alcohol dehydrogenase
JDW14_05635	COG3759	membrane
JDW14_05640	COG1846	Transcriptional regulator
JDW14_05665	COG1131	(ABC) transporter
JDW14_05690	COG2205	protein histidine kinase activity
JDW14_05695	COG0745	RESPONSE REGULATOR receiver
JDW14_05720	COG0617	tRNA 3'-terminal CCA addition
JDW14_05740	COG2211	Major facilitator Superfamily
JDW14_05770	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JDW14_05775	COG0358	DNA primase activity
JDW14_05780	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JDW14_05785	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JDW14_05790	COG0544	peptidyl-prolyl cis-trans isomerase activity
JDW14_05795	COG3331	DNA recombination
JDW14_05800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JDW14_05820	COG3409	Peptidoglycan-binding domain 1 protein
JDW14_05820	COG0793	Belongs to the peptidase S41A family
JDW14_05825	COG0813	purine-nucleoside phosphorylase activity
JDW14_05840	COG2382	esterase
JDW14_05850	COG0464	growth
JDW14_05855	COG0484	heat shock protein binding
JDW14_05860	COG0443	Heat shock 70 kDa protein
JDW14_05865	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JDW14_05875	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JDW14_05880	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JDW14_05885	COG0196	riboflavin kinase activity
JDW14_05890	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JDW14_05895	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JDW14_05900	COG0187	DNA topoisomerase II activity
JDW14_05910	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JDW14_05930	COG1125	glycine betaine transport
JDW14_05950	COG1136	(ABC) transporter
JDW14_05970	COG3833	ABC-type maltose transport systems, permease component
JDW14_05985	COG1053	succinate dehydrogenase
JDW14_05990	COG1053	succinate dehydrogenase
JDW14_05995	COG1064	alcohol dehydrogenase
JDW14_06005	COG0596	Alpha beta hydrolase
JDW14_06015	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JDW14_06025	COG5646	InterPro IPR014922
JDW14_06030	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JDW14_06035	COG0488	(ABC) transporter
JDW14_06040	COG0318	PFAM AMP-dependent synthetase and ligase
JDW14_06045	COG1266	CAAX protease self-immunity
JDW14_06055	COG1136	(ABC) transporter
JDW14_06080	COG1454	alcohol dehydrogenase
JDW14_06080	COG1012	belongs to the aldehyde dehydrogenase family
JDW14_06125	COG3583	domain protein
JDW14_06130	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JDW14_06135	COG1846	Transcriptional regulator
JDW14_06155	COG1597	lipid kinase activity
JDW14_06170	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JDW14_06175	COG0626	cystathionine gamma-synthase activity
JDW14_06185	COG0785	Cytochrome C biogenesis protein
JDW14_06195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JDW14_06200	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JDW14_06200	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JDW14_06205	COG3279	Response regulator of the LytR AlgR family
JDW14_06210	COG2972	Histidine kinase
JDW14_06220	COG2272	Belongs to the type-B carboxylesterase lipase family
JDW14_06225	COG2723	6-phospho-beta-galactosidase activity
JDW14_06245	COG1263	PTS System
JDW14_06245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JDW14_06245	COG2190	(PTS) system
JDW14_06250	COG3711	transcriptional antiterminator
JDW14_06260	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JDW14_06265	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JDW14_06275	COG4109	DRTGG domain
JDW14_06285	COG2315	Protein conserved in bacteria
JDW14_06295	COG1316	TRANSCRIPTIONal
JDW14_06305	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JDW14_06310	COG0716	FMN binding
JDW14_06315	COG2309	aminopeptidase activity
JDW14_06325	COG0438	transferase activity, transferring glycosyl groups
JDW14_06330	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JDW14_06335	COG1490	D-aminoacyl-tRNA deacylase activity
JDW14_06340	COG2514	catechol 2,3-dioxygenase activity
JDW14_06345	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JDW14_06350	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JDW14_06350	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JDW14_06360	COG0300	oxidoreductase activity
JDW14_06370	COG2755	lipolytic protein G-D-S-L family
JDW14_06370	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JDW14_06380	COG0751	glycine-tRNA ligase activity
JDW14_06385	COG0752	glycyl-tRNA synthetase alpha subunit
JDW14_06400	COG0719	Fe-S assembly protein
JDW14_06405	COG0822	iron-sulfur transferase activity
JDW14_06410	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JDW14_06415	COG0719	Fe-S assembly protein
JDW14_06440	COG1070	Carbohydrate kinase
JDW14_06445	COG2115	Belongs to the xylose isomerase family
JDW14_06450	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JDW14_06455	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JDW14_06460	COG0124	histidyl-tRNA synthetase
JDW14_06470	COG0803	Belongs to the bacterial solute-binding protein 9 family
JDW14_06475	COG0860	N-Acetylmuramoyl-L-alanine amidase
JDW14_06475	COG3103	Sh3 type 3 domain protein
JDW14_06475	COG4991	sh3 domain protein
JDW14_06480	COG0233	cytoplasmic translational termination
JDW14_06485	COG0577	efflux transmembrane transporter activity
JDW14_06490	COG1136	(ABC) transporter
JDW14_06505	COG1472	Belongs to the glycosyl hydrolase 3 family
JDW14_06520	COG0697	spore germination
JDW14_06530	COG1811	Na channel or pump
JDW14_06540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JDW14_06545	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JDW14_06550	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JDW14_06555	COG2264	protein methyltransferase activity
JDW14_06565	COG3599	regulation of cell shape
JDW14_06575	COG0116	Belongs to the methyltransferase superfamily
JDW14_06585	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JDW14_06590	COG0439	Biotin carboxylase
JDW14_06600	COG1984	allophanate hydrolase subunit 2
JDW14_06605	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JDW14_06610	COG1914	H( )-stimulated, divalent metal cation uptake system
JDW14_06615	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JDW14_06620	COG0154	amidase activity
JDW14_06630	COG4851	CamS sex pheromone cAM373 precursor
JDW14_06635	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JDW14_06650	COG2226	methyltransferase
JDW14_06665	COG0534	Mate efflux family protein
JDW14_06670	COG0433	COG0433 Predicted ATPase
JDW14_06675	COG0534	Mate efflux family protein
JDW14_06685	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JDW14_06705	COG1609	Transcriptional regulator
JDW14_06710	COG3425	synthase
JDW14_06725	COG0628	permease
JDW14_06730	COG2706	6-phosphogluconolactonase activity
JDW14_06755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JDW14_06760	COG3458	cephalosporin-C deacetylase activity
JDW14_06770	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
JDW14_06775	COG0395	ABC-type sugar transport system, permease component
JDW14_06780	COG1175	transmembrane transport
JDW14_06800	COG0604	alcohol dehydrogenase
JDW14_06805	COG4608	Belongs to the ABC transporter superfamily
JDW14_06810	COG0444	Belongs to the ABC transporter superfamily
JDW14_06815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JDW14_06820	COG0601	transmembrane transport
JDW14_06825	COG4166	transmembrane transport
JDW14_06830	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
JDW14_06835	COG3257	ureidoglycine aminohydrolase activity
JDW14_06840	COG0549	Belongs to the carbamate kinase family
JDW14_06850	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JDW14_06860	COG1301	dicarboxylic acid transport
JDW14_06865	COG2271	Major facilitator Superfamily
JDW14_06870	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JDW14_06875	COG2508	Transcriptional regulator
JDW14_06885	COG0556	nucleotide-excision repair
JDW14_06955	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
JDW14_06985	COG3645	SOS response
JDW14_07000	COG0519	Catalyzes the synthesis of GMP from XMP
JDW14_07000	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JDW14_07010	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JDW14_07025	COG1304	FMN binding
JDW14_07030	COG2081	HI0933 family
JDW14_07045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JDW14_07110	COG2378	regulation of single-species biofilm formation
JDW14_07135	COG0270	DNA (cytosine-5-)-methyltransferase activity
JDW14_07175	COG3344	reverse transcriptase
JDW14_07195	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JDW14_07210	COG0242	peptide deformylase activity
JDW14_07215	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JDW14_07225	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JDW14_07230	COG0557	exoribonuclease II activity
JDW14_07245	COG3764	Sortase (surface protein transpeptidase)
JDW14_07260	COG1668	transmembrane transport
JDW14_07265	COG4152	abc transporter atp-binding protein
JDW14_07280	COG0542	response to heat
JDW14_07290	COG1442	glycosyl transferase family 8
JDW14_07295	COG1442	glycosyl transferase family 8
JDW14_07300	COG1442	glycosyl transferase family 8
JDW14_07300	COG1216	Glycosyl transferase, family 2
JDW14_07330	COG0438	transferase activity, transferring glycosyl groups
JDW14_07360	COG1086	Polysaccharide biosynthesis protein
JDW14_07375	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JDW14_07385	COG1316	TRANSCRIPTIONal
JDW14_07395	COG0489	protein tyrosine kinase activity
JDW14_07485	COG0166	Belongs to the GPI family
JDW14_07490	COG0539	negative regulation of cytoplasmic translation
JDW14_07495	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JDW14_07500	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
JDW14_07505	COG0492	ferredoxin-NADP+ reductase activity
JDW14_07510	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JDW14_07520	COG2183	response to ionizing radiation
JDW14_07545	COG3557	Belongs to the UPF0374 family
JDW14_07550	COG1132	(ABC) transporter
JDW14_07565	COG2137	regulation of response to DNA damage stimulus
JDW14_07570	COG0497	DNA recombination
JDW14_07575	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JDW14_07580	COG0142	geranyltranstransferase activity
JDW14_07585	COG1722	exodeoxyribonuclease VII activity
JDW14_07590	COG1570	exodeoxyribonuclease VII activity
JDW14_07600	COG0475	glutathione-regulated potassium exporter activity
JDW14_07610	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JDW14_07615	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JDW14_07625	COG1803	Methylglyoxal synthase
JDW14_07640	COG2003	Belongs to the UPF0758 family
JDW14_07645	COG2003	Belongs to the UPF0758 family
JDW14_07650	COG0285	dihydrofolate synthase activity
JDW14_07655	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JDW14_07695	COG1316	TRANSCRIPTIONal
JDW14_07700	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JDW14_07705	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JDW14_07730	COG0366	Alpha amylase catalytic
JDW14_07735	COG0395	ABC-type sugar transport system, permease component
JDW14_07740	COG1175	transmembrane transport
JDW14_07745	COG1653	transport
JDW14_07750	COG3345	alpha-galactosidase
JDW14_07755	COG2207	Transcriptional regulator
JDW14_07760	COG1114	Component of the transport system for branched-chain amino acids
JDW14_07765	COG0280	phosphate acetyltransferase
JDW14_07770	COG1854	S-ribosylhomocysteine lyase activity
JDW14_07775	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JDW14_07780	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JDW14_07785	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JDW14_07790	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JDW14_07795	COG0037	tRNA processing
JDW14_07800	COG1098	S1 RNA binding domain
JDW14_07810	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JDW14_07815	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JDW14_07820	COG0193	aminoacyl-tRNA hydrolase activity
JDW14_07825	COG0039	L-malate dehydrogenase activity
JDW14_07830	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JDW14_07835	COG1302	Protein conserved in bacteria
JDW14_07840	COG0006	proline dipeptidase activity
JDW14_07875	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JDW14_07885	COG5503	Protein of unknown function (DUF1447)
JDW14_07905	COG1053	succinate dehydrogenase
JDW14_07905	COG3976	FMN-binding domain protein
JDW14_07910	COG2184	nucleotidyltransferase activity
JDW14_07915	COG1131	(ABC) transporter
JDW14_07940	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JDW14_07950	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JDW14_07955	COG2738	Putative neutral zinc metallopeptidase
JDW14_07970	COG1131	(ABC) transporter
JDW14_07980	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JDW14_07985	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JDW14_07990	COG1335	isochorismatase
JDW14_08005	COG2239	Acts as a magnesium transporter
JDW14_08010	COG0564	pseudouridine synthase activity
JDW14_08020	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JDW14_08025	COG2357	RelA SpoT domain protein
JDW14_08035	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JDW14_08040	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JDW14_08045	COG1396	sequence-specific DNA binding
JDW14_08055	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JDW14_08060	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JDW14_08070	COG0446	pyridine nucleotide-disulphide oxidoreductase
JDW14_08080	COG1363	Peptidase, m42
JDW14_08110	COG4989	oxidoreductase activity
JDW14_08115	COG2017	converts alpha-aldose to the beta-anomer
JDW14_08120	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JDW14_08140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JDW14_08150	COG0254	rRNA binding
JDW14_08190	COG1393	Belongs to the ArsC family
JDW14_08205	COG0488	(ABC) transporter
JDW14_08215	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JDW14_08225	COG1323	Belongs to the UPF0348 family
JDW14_08230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JDW14_08235	COG0799	negative regulation of ribosome biogenesis
JDW14_08240	COG1713	HD superfamily hydrolase involved in NAD metabolism
JDW14_08245	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JDW14_08250	COG1534	Rna-binding protein
JDW14_08255	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JDW14_08260	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JDW14_08270	COG1272	protein, Hemolysin III
JDW14_08275	COG1764	response to oxidative stress
JDW14_08285	COG0438	transferase activity, transferring glycosyl groups
JDW14_08300	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JDW14_08325	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JDW14_08335	COG1686	Belongs to the peptidase S11 family
JDW14_08355	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JDW14_08365	COG1126	abc transporter atp-binding protein
JDW14_08370	COG0765	amino acid transport
JDW14_08385	COG1484	DNA-dependent DNA replication
JDW14_08400	COG0237	dephospho-CoA kinase activity
JDW14_08405	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JDW14_08410	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JDW14_08410	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JDW14_08425	COG3655	Transcriptional regulator
JDW14_08435	COG1611	Belongs to the LOG family
JDW14_08440	COG0148	phosphopyruvate hydratase activity
JDW14_08455	COG0126	phosphoglycerate kinase activity
JDW14_08465	COG2390	Transcriptional regulator
JDW14_08470	COG0740	serine-type endopeptidase activity
JDW14_08490	COG3842	ATPase activity
JDW14_08495	COG0737	Belongs to the 5'-nucleotidase family
JDW14_08505	COG0459	protein refolding
JDW14_08510	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JDW14_08515	COG1979	alcohol dehydrogenase
JDW14_08535	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JDW14_08560	COG2249	NAD(P)H dehydrogenase (quinone) activity
JDW14_08570	COG5002	protein histidine kinase activity
JDW14_08570	COG3850	Histidine kinase
JDW14_08575	COG0745	RESPONSE REGULATOR receiver
JDW14_08580	COG0629	single-stranded DNA binding
JDW14_08585	COG1481	regulation of sporulation
JDW14_08590	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JDW14_08595	COG1660	Displays ATPase and GTPase activities
JDW14_08600	COG0488	(ABC) transporter
JDW14_08620	COG0095	Lipoate-protein ligase
JDW14_08625	COG1078	dGTPase activity
JDW14_08640	COG1464	Belongs to the NlpA lipoprotein family
JDW14_08645	COG1464	Belongs to the NlpA lipoprotein family
JDW14_08650	COG2011	ABC-type metal ion transport system permease component
JDW14_08655	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JDW14_08660	COG0436	Aminotransferase
JDW14_08665	COG1942	4-Oxalocrotonate Tautomerase
JDW14_08685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JDW14_08700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JDW14_08775	COG4974	Belongs to the 'phage' integrase family
JDW14_08785	COG0513	Belongs to the DEAD box helicase family
JDW14_08915	COG2116	formate transmembrane transporter activity
JDW14_08920	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JDW14_08935	COG1132	(ABC) transporter
JDW14_08940	COG3850	Histidine kinase
JDW14_08940	COG5002	protein histidine kinase activity
JDW14_08945	COG0745	RESPONSE REGULATOR receiver
JDW14_08950	COG1418	mRNA catabolic process
JDW14_08965	COG1428	Deoxynucleoside kinase
JDW14_08975	COG1309	transcriptional regulator
JDW14_08995	COG3408	Glycogen debranching enzyme
JDW14_09005	COG3250	beta-galactosidase activity
JDW14_09010	COG2211	Major facilitator Superfamily
JDW14_09015	COG2207	Transcriptional regulator
JDW14_09025	COG3250	beta-galactosidase activity
JDW14_09030	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JDW14_09040	COG1447	Phosphotransferase system cellobiose-specific component IIA
JDW14_09055	COG3250	beta-galactosidase activity
JDW14_09060	COG1917	Cupin 2, conserved barrel domain protein
JDW14_09060	COG2169	Transcriptional regulator
JDW14_09070	COG3804	dihydrodipicolinate reductase
JDW14_09080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JDW14_09085	COG1902	pentaerythritol trinitrate reductase activity
JDW14_09095	COG3250	beta-galactosidase activity
JDW14_09115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JDW14_09125	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JDW14_09130	COG3442	glutamine amidotransferase
JDW14_09135	COG0095	Lipoate-protein ligase
JDW14_09145	COG1363	Peptidase, m42
JDW14_09160	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JDW14_09165	COG3976	FMN-binding domain protein
JDW14_09165	COG0431	NADPH-dependent FMN reductase
JDW14_09165	COG1053	succinate dehydrogenase
JDW14_09170	COG3976	FMN-binding domain protein
JDW14_09170	COG0431	NADPH-dependent FMN reductase
JDW14_09170	COG1053	succinate dehydrogenase
JDW14_09180	COG2832	Protein of unknown function (DUF454)
JDW14_09210	COG0602	queuosine metabolic process
JDW14_09215	COG1328	CTP reductase activity
JDW14_09235	COG1496	oxidoreductase activity
JDW14_09255	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JDW14_09260	COG1737	Transcriptional regulator
JDW14_09265	COG1917	Cupin 2, conserved barrel domain protein
JDW14_09265	COG4977	sequence-specific DNA binding
JDW14_09285	COG3250	beta-galactosidase activity
JDW14_09305	COG0395	ABC-type sugar transport system, permease component
JDW14_09310	COG1175	transmembrane transport
JDW14_09315	COG1904	glucuronate isomerase
JDW14_09325	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
JDW14_09330	COG1028	Short-chain dehydrogenase reductase Sdr
JDW14_09335	COG1312	Catalyzes the dehydration of D-mannonate
JDW14_09340	COG0534	Mate efflux family protein
JDW14_09345	COG2207	Transcriptional regulator
JDW14_09360	COG1073	alpha beta
JDW14_09365	COG1653	transport
JDW14_09375	COG1653	transport
JDW14_09385	COG4209	transmembrane transport
JDW14_09390	COG0395	ABC-type sugar transport system, permease component
JDW14_09395	COG1414	Transcriptional regulator
JDW14_09420	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
JDW14_09425	COG3254	rhamnose metabolic process
JDW14_09440	COG2755	lipolytic protein G-D-S-L family
JDW14_09450	COG1028	Short-chain dehydrogenase reductase Sdr
JDW14_09455	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
JDW14_09465	COG0800	Aldolase
JDW14_09480	COG1028	Short-chain dehydrogenase reductase Sdr
JDW14_09485	COG1312	Catalyzes the dehydration of D-mannonate
JDW14_09495	COG0800	Aldolase
JDW14_09500	COG2186	Transcriptional regulator
JDW14_09505	COG3250	beta-galactosidase activity
JDW14_09515	COG3250	beta-galactosidase activity
JDW14_09520	COG2272	Belongs to the type-B carboxylesterase lipase family
JDW14_09525	COG2211	Major facilitator Superfamily
JDW14_09535	COG2211	Major facilitator Superfamily
JDW14_09540	COG3976	FMN-binding domain protein
JDW14_09540	COG1053	succinate dehydrogenase
JDW14_09550	COG0517	IMP dehydrogenase activity
JDW14_09550	COG0516	GMP reductase activity
JDW14_09560	COG0012	GTP binding
JDW14_09565	COG4481	Protein conserved in bacteria
JDW14_09570	COG1475	DNA binding
JDW14_09575	COG1192	Involved in chromosome partitioning
JDW14_09585	COG0778	Nitroreductase
JDW14_09590	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JDW14_09595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JDW14_09600	COG1970	mechanosensitive ion channel activity
JDW14_09605	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JDW14_09610	COG0436	Aminotransferase
JDW14_09620	COG1396	sequence-specific DNA binding
JDW14_09640	COG0745	RESPONSE REGULATOR receiver
JDW14_09645	COG2205	protein histidine kinase activity
JDW14_09650	COG2731	YhcH YjgK YiaL family protein
JDW14_09655	COG2818	Glycosylase
JDW14_09670	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JDW14_09675	COG2827	Endonuclease containing a URI domain
JDW14_09680	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JDW14_09695	COG3870	Protein conserved in bacteria
JDW14_09700	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JDW14_09710	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JDW14_09715	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JDW14_09725	COG0590	tRNA wobble adenosine to inosine editing
JDW14_09745	COG0542	response to heat
JDW14_09855	COG0569	domain protein
JDW14_09860	COG1473	amidohydrolase
JDW14_09865	COG0445	tRNA wobble uridine modification
JDW14_09870	COG1051	belongs to the nudix hydrolase family
JDW14_09875	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JDW14_09880	COG2188	Transcriptional regulator
JDW14_09890	COG0366	Alpha amylase catalytic
JDW14_09895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JDW14_09895	COG1263	PTS System
JDW14_09900	COG1847	R3H domain protein
JDW14_09905	COG0706	membrane insertase activity
JDW14_09915	COG0230	Belongs to the bacterial ribosomal protein bL34 family