locus-tag	class	description
AWM71_00045	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AWM71_00060	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AWM71_00075	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AWM71_00080	ENOG4105D01	(LipO)protein
AWM71_00085	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AWM71_00090	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AWM71_00095	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AWM71_00105	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
AWM71_00115	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AWM71_00125	ENOG4105CCI	Myosin-Cross-Reactive Antigen
AWM71_00130	ENOG4105ST3	Transcriptional regulator
AWM71_00160	ENOG410854A	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AWM71_00185	ENOG4105CHU	acetyl-coa acetyltransferase
AWM71_00190	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
AWM71_00195	ENOG4105CY2	Citrate transporter
AWM71_00205	ENOG4105E39	Enoyl-CoA hydratase
AWM71_00210	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AWM71_00250	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AWM71_00255	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AWM71_00260	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AWM71_00265	ENOG4105DX0	Hemolysin A
AWM71_00270	ENOG4105CTB	Polyprenyl synthetase
AWM71_00275	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AWM71_00280	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AWM71_00285	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AWM71_00300	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AWM71_00305	ENOG4105DC7	peptidase M24
AWM71_00330	ENOG4108VAU	general secretion pathway protein G
AWM71_00375	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
AWM71_00380	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
AWM71_00385	ENOG4106C6A	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AWM71_00400	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
AWM71_00410	ENOG4105DM4	PTS System
AWM71_00415	ENOG4108NGU	Transcriptional regulator
AWM71_00445	ENOG4105Y7M	Transcriptional regulator, TetR family
AWM71_00460	ENOG4105CJ1	ABC, transporter
AWM71_00490	ENOG4105WH1	Two component transcriptional regulator luxr family
AWM71_00500	ENOG4105D01	(LipO)protein
AWM71_00505	ENOG4105C75	arginyL-tRNA synthetase
AWM71_00510	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AWM71_00525	ENOG4107RNN	dihydropyrimidinase (EC 3.5.2.2)
AWM71_00540	ENOG4108YYH	Nadph-dependent fmn reductase
AWM71_00545	ENOG4108K79	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AWM71_00550	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AWM71_00555	ENOG4105BZ1	(ABC) transporter
AWM71_00560	ENOG4105BZ1	(ABC) transporter
AWM71_00575	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AWM71_00590	ENOG4105F6E	Acyl-transferase
AWM71_00595	ENOG4105VXM	UPF0154 protein
AWM71_00600	ENOG4105C34	Pseudouridine synthase
AWM71_00605	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AWM71_00620	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
AWM71_00625	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AWM71_00630	ENOG4105EGD	dinuclear metal center protein, YbgI family
AWM71_00665	ENOG4108R96	Methyltransferase, YaeB family
AWM71_00670	ENOG4107QRI	Phosphoketolase
AWM71_00690	ENOG4105C9K	Endothelin-converting enzyme 1
AWM71_00705	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
AWM71_00725	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
AWM71_00735	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
AWM71_00740	ENOG4105C3J	Cysteine desulfurase
AWM71_00745	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
AWM71_00770	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AWM71_00785	ENOG4108YZ4	nudix hydrolase
AWM71_00805	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AWM71_00815	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AWM71_00830	ENOG41067XK	integral membrane protein
AWM71_00835	ENOG4105DFA	alanine racemase domain protein
AWM71_00840	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AWM71_00850	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
AWM71_00855	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AWM71_00860	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AWM71_00865	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AWM71_00870	ENOG4105CJN	penicillin-binding protein
AWM71_00880	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AWM71_00890	ENOG4105C83	adenylosuccinate lyase
AWM71_00895	ENOG4105C12	Phosphoribosylglycinamide synthetase
AWM71_00900	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AWM71_00905	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AWM71_00915	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AWM71_00920	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AWM71_00925	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
AWM71_00935	ENOG4105C8V	SAICAR synthetase
AWM71_00940	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AWM71_00945	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AWM71_00950	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AWM71_00975	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AWM71_00980	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AWM71_01000	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
AWM71_01005	ENOG4105MMD	transcriptional regulator
AWM71_01025	ENOG4107R84	Peptidase dimerisation domain
AWM71_01030	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AWM71_01035	ENOG4105CP7	Triose-phosphate isomerase
AWM71_01040	ENOG4105BZA	Phosphoglycerate kinase
AWM71_01045	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AWM71_01055	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AWM71_01065	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AWM71_01095	ENOG4105DM4	PTS System
AWM71_01100	ENOG4105DE4	1-phosphofructokinase
AWM71_01105	ENOG4105E98	transcriptional regulator DeoR family
AWM71_01245	ENOG4107QYV	phosphohexose isomerase
AWM71_01255	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AWM71_01265	ENOG4105CAY	ferredoxin--nadp reductase
AWM71_01275	ENOG4105CHM	Aminotransferase
AWM71_01290	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AWM71_01295	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AWM71_01310	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AWM71_01320	ENOG4105D7T	ABC transporter
AWM71_01340	ENOG4108UMN	azlc family
AWM71_01345	ENOG4108JJB	ABC transporter
AWM71_01365	ENOG4105K8N	protein family UPF0079, ATPase
AWM71_01370	ENOG4105K70	DNA-binding protein
AWM71_01375	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AWM71_01380	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AWM71_01385	ENOG4105CAT	Cytidine monophosphate kinase
AWM71_01390	ENOG41068JE	domain protein
AWM71_01395	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AWM71_01420	ENOG4105FE9	pseudouridine synthase
AWM71_01425	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AWM71_01430	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
AWM71_01450	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AWM71_01455	ENOG4105QNR	S1 RNA binding domain protein
AWM71_01470	ENOG4105E5Q	amino acid AbC transporter
AWM71_01480	ENOG4105D01	(LipO)protein
AWM71_01485	ENOG4108UMI	ABC transporter, permease
AWM71_01490	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AWM71_01495	ENOG4105HUF	DNA protection during starvation protein
AWM71_01500	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AWM71_01505	ENOG4105VJV	50s ribosomal protein L35
AWM71_01510	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AWM71_01525	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
AWM71_01530	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AWM71_01535	ENOG410667J	hydrolase
AWM71_01540	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AWM71_01545	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AWM71_01550	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AWM71_01555	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
AWM71_01560	ENOG4105CB5	ATP-dependent DNA helicase recG
AWM71_01565	ENOG4105DEN	Luciferase family
AWM71_01570	ENOG4105DP4	dak2 domain fusion protein ylov
AWM71_01575	ENOG4108ZAA	Alkaline-shock protein
AWM71_01580	ENOG4105VB9	50S ribosomal protein l28
AWM71_01590	ENOG4105DJV	ribulose-phosphate 3-epimerase
AWM71_01600	ENOG4105D9P	serine threonine protein kinase
AWM71_01610	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AWM71_01615	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AWM71_01620	ENOG4105C25	Primosomal protein n'
AWM71_01625	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AWM71_01630	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AWM71_01640	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AWM71_01655	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AWM71_01665	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AWM71_01680	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AWM71_01700	ENOG4105KQC	Competence protein
AWM71_01705	ENOG4106H78	methyltransferase
AWM71_01715	ENOG4105CNI	cell division protein FtsW
AWM71_01720	ENOG4105CI3	gtp-binding protein typa
AWM71_01725	ENOG4105ECY	inositol monophosphatase
AWM71_01730	ENOG4105WBI	UPF0223 protein
AWM71_01735	ENOG4105DRP	amino acid AbC transporter
AWM71_01740	ENOG4105EAD	ABC transporter
AWM71_01745	ENOG4105CT1	(ABC) transporter
AWM71_01775	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AWM71_01780	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AWM71_01785	ENOG4107QID	Threonine synthase
AWM71_01795	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
AWM71_01805	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
AWM71_01810	ENOG4108JQ7	(ABC) transporter
AWM71_01820	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AWM71_01825	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AWM71_01860	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AWM71_01900	ENOG4108UZE	carboxy-peptidase
AWM71_01905	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AWM71_01910	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AWM71_01920	ENOG4108QV3	biosynthesis protein
AWM71_01935	ENOG4108Z4K	mutator MutT protein
AWM71_01950	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
AWM71_01955	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AWM71_01975	ENOG4105NQC	Flavodoxin
AWM71_01985	ENOG4107QSI	ABC, transporter
AWM71_01990	ENOG4108ZJ4	polysaccharide deacetylase
AWM71_02005	ENOG4105K64	Glycosyl transferase, family 2
AWM71_02010	ENOG4107QRS	glycosyltransferase group 2 family protein
AWM71_02020	ENOG4105D2T	synthase
AWM71_02025	ENOG4105F0R	Cytidylyltransferase
AWM71_02030	ENOG4108ZJ4	polysaccharide deacetylase
AWM71_02070	ENOG4105DFT	pur operon repressor
AWM71_02080	ENOG4105FDK	ABC transporter
AWM71_02090	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AWM71_02095	ENOG4105W42	Veg protein
AWM71_02100	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AWM71_02105	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
AWM71_02110	ENOG4105F8V	Hydrolase, tatD family
AWM71_02115	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AWM71_02125	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
AWM71_02135	ENOG4105C5F	glutamine synthetase
AWM71_02150	ENOG4105CHM	Aminotransferase
AWM71_02155	ENOG4108ZB6	transcriptional regulator AsnC family
AWM71_02165	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AWM71_02170	ENOG4105C0H	protease
AWM71_02175	ENOG4105Q2H	domain protein
AWM71_02200	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AWM71_02205	ENOG4107X35	defense response to bacterium
AWM71_02210	ENOG4108UZ3	Transporter
AWM71_02215	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AWM71_02230	ENOG4105DT3	PTS system, galactitol-specific IIc component
AWM71_02245	ENOG4105D2N	Aldolase
AWM71_02260	ENOG4105ETD	TRANSCRIPTIONal
AWM71_02275	ENOG4105CI1	PTS System
AWM71_02280	ENOG4105HMI	Membrane
AWM71_02285	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AWM71_02295	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
AWM71_02315	ENOG4108RVA	ribokinase
AWM71_02320	ENOG4105DF9	Lipoate-protein, ligase
AWM71_02330	ENOG4105DSE	periplasmic solute binding protein
AWM71_02345	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AWM71_02350	ENOG4105E2Z	phosphate ABC transporter (Permease
AWM71_02355	ENOG4105C8U	phosphate abc transporter
AWM71_02360	ENOG4107S17	Phosphate-binding protein
AWM71_02365	ENOG4105BZU	Histidine kinase
AWM71_02370	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AWM71_02375	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AWM71_02380	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AWM71_02390	ENOG41081UC	Inherit from COG: Competence protein
AWM71_02400	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AWM71_02410	ENOG4105KV4	Transcriptional regulator
AWM71_02415	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AWM71_02425	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AWM71_02435	ENOG4105EA8	2-Nitropropane dioxygenase
AWM71_02440	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
AWM71_02450	ENOG4105CHR	reductase
AWM71_02465	ENOG410787A	Pts system, glucitol sorbitol-specific
AWM71_02470	ENOG4105DZY	Pts system, glucitol sorbitol-specific
AWM71_02480	ENOG4105CUC	YeeE YedE family protein
AWM71_02485	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AWM71_02495	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
AWM71_02500	ENOG4106FTQ	Taurine ABC transporter, periplasmic
AWM71_02505	ENOG4108IY8	ABC, transporter
AWM71_02510	ENOG4105C5Q	Transcriptional regulator
AWM71_02515	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
AWM71_02520	ENOG4105CMQ	Chloride channel
AWM71_02525	ENOG4105CGK	Exodeoxyribonuclease III
AWM71_02530	ENOG4105M0C	cytoplasmic protein
AWM71_02540	ENOG4105DR4	Methyltransferase
AWM71_02550	ENOG4105BZU	Histidine kinase
AWM71_02555	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AWM71_02560	ENOG4108UUM	single-stranded DNA-binding protein
AWM71_02565	ENOG4105CIE	May be required for sporulation (By similarity)
AWM71_02570	ENOG4105CHW	UPF0052 protein
AWM71_02575	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AWM71_02585	ENOG4105C3M	thioredoxin reductase
AWM71_02590	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AWM71_02595	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AWM71_02600	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AWM71_02605	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
AWM71_02620	ENOG4105EYH	Exonuclease
AWM71_02625	ENOG4107RFY	SbcCD D subunit
AWM71_02630	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AWM71_02635	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AWM71_02640	ENOG4105CI1	PTS System
AWM71_02645	ENOG410901P	UPF0249 protein
AWM71_02650	ENOG4105C5Y	PTS System
AWM71_02655	ENOG4105CID	antiterminator
AWM71_02660	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
AWM71_02665	ENOG4105C5Y	PTS System
AWM71_02680	ENOG4105CJ2	(LipO)protein
AWM71_02685	ENOG4105EAH	synthase
AWM71_02690	ENOG4105CEP	NADH dehydrogenase
AWM71_02700	ENOG4107EFR	Flavocytochrome c
AWM71_02735	ENOG4105BZ1	(ABC) transporter
AWM71_02820	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
AWM71_02845	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AWM71_02850	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
AWM71_02855	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AWM71_02860	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AWM71_02865	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AWM71_02875	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AWM71_02880	ENOG4105C4R	Atp-dependent dna helicase
AWM71_02895	ENOG4105D01	(LipO)protein
AWM71_02900	ENOG4105CSA	Coproporphyrinogen iii oxidase
AWM71_02905	ENOG4108IV0	ABC, transporter
AWM71_02910	ENOG4105C0Z	ABC transporter
AWM71_02915	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
AWM71_02920	ENOG4105C32	Amino acid ABC transporter (Permease)
AWM71_02925	ENOG4105CP9	extracellular ligand-binding receptor
AWM71_02940	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AWM71_02950	ENOG4105CTP	PilT protein domain protein
AWM71_02955	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AWM71_02960	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AWM71_02965	ENOG4105E66	phosphoriboisomerase A
AWM71_02975	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
AWM71_02985	ENOG4105DFM	M18 family aminopeptidase
AWM71_02990	ENOG4107EFR	Flavocytochrome c
AWM71_02995	ENOG4107QPK	)-transporter
AWM71_03000	ENOG4105C9Q	fumarate hydratase class II
AWM71_03010	ENOG4105BZG	amino acid carrier protein
AWM71_03015	ENOG4105DFD	Na H antiporter
AWM71_03020	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AWM71_03035	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AWM71_03055	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AWM71_03070	ENOG4105C3G	gtp-binding protein
AWM71_03075	ENOG4105VDK	protein, conserved in bacteria
AWM71_03080	ENOG4105FA0	parb-like partition protein
AWM71_03085	ENOG4107QJE	Chromosome Partitioning Protein
AWM71_03090	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AWM71_03095	ENOG4108HRK	Histidine kinase
AWM71_03100	ENOG4105DY9	regulatoR
AWM71_03110	ENOG41067MG	lrgb family
AWM71_03120	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AWM71_03125	ENOG4105DZW	Dipeptidase
AWM71_03130	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AWM71_03135	ENOG4108S4A	n-acetylmuramoyl-l-alanine amidase
AWM71_03140	ENOG4105C6T	cysteine synthase
AWM71_03145	ENOG4105D7W	serine acetyltransferase
AWM71_03155	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
AWM71_03160	ENOG4105DIW	FeS assembly protein SUFB
AWM71_03165	ENOG4108UNV	SUF system FeS assembly protein, NifU family
AWM71_03175	ENOG4105JRK	feS assembly protein SufD
AWM71_03185	ENOG4105VG1	fes assembly suf system protein
AWM71_03195	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AWM71_03205	ENOG4105VG0	50S ribosomal protein l34
AWM71_03225	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AWM71_03265	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AWM71_03270	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AWM71_03275	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AWM71_03300	ENOG4108UUM	single-stranded DNA-binding protein
AWM71_03305	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AWM71_03315	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AWM71_03320	ENOG4105CDU	Replicative dna helicase
AWM71_03355	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AWM71_03405	ENOG4105EGI	Transcriptional regulator
AWM71_03415	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AWM71_03420	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AWM71_03425	ENOG4107U5W	ybbr family
AWM71_03450	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AWM71_03455	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AWM71_03465	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
AWM71_03480	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AWM71_03490	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AWM71_03500	ENOG4105DUM	transcriptional regulator, lysR family
AWM71_03505	ENOG4105C3M	thioredoxin reductase
AWM71_03510	ENOG4105K63	Thioredoxin
AWM71_03515	ENOG4108MR7	Arylsulfotransferase
AWM71_03520	ENOG4105ECY	inositol monophosphatase
AWM71_03525	ENOG4105DKT	Transcriptional regulator
AWM71_03530	ENOG4105E98	transcriptional regulator DeoR family
AWM71_03540	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
AWM71_03545	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
AWM71_03560	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
AWM71_03585	ENOG4105DKT	Transcriptional regulator
AWM71_03595	ENOG4105YHU	PTS system
AWM71_03600	ENOG4108IQ3	PTS system
AWM71_03605	ENOG4105ETZ	PTS System
AWM71_03610	ENOG4105F3R	pts system mannose fructose sorbose family iid
AWM71_03615	ENOG4105DXH	Alcohol dehydrogenase zinc-binding domain protein
AWM71_03620	ENOG4105CHR	reductase
AWM71_03625	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
AWM71_03645	ENOG410667J	hydrolase
AWM71_03655	ENOG4105I08	Pseudouridine synthase
AWM71_03670	ENOG4108S4H	thioesterase Superfamily protein
AWM71_03680	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AWM71_03685	ENOG41069HH	4-oxalocrotonate tautomerase
AWM71_03690	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AWM71_03705	ENOG4105DZR	Type I site-specific deoxyribonuclease
AWM71_03725	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
AWM71_03760	ENOG4105E98	transcriptional regulator DeoR family
AWM71_03770	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
AWM71_03790	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
AWM71_03795	ENOG4105CR5	Class II aldolase adducin family protein
AWM71_03800	ENOG4105EF1	ribulokinase
AWM71_03805	ENOG41080QX	K07048 phosphotriesterase-related protein
AWM71_03820	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
AWM71_03835	ENOG4105DKT	Transcriptional regulator
AWM71_03840	ENOG4107QRI	Phosphoketolase
AWM71_03855	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
AWM71_03860	ENOG4105VPS	UPF0291 protein
AWM71_03865	ENOG41072GX	Peptidase M22 Glycoprotease
AWM71_03870	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
AWM71_03875	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AWM71_03880	ENOG4105C5H	ABC transporter
AWM71_03885	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
AWM71_03895	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AWM71_03900	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AWM71_03905	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AWM71_03910	ENOG4105C83	adenylosuccinate lyase
AWM71_03925	ENOG4108SGK	Tetr family transcriptional regulator
AWM71_03955	ENOG4105DYB	Isoaspartyl dipeptidase
AWM71_03960	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
AWM71_03965	ENOG4105E5Q	amino acid AbC transporter
AWM71_03970	ENOG4105CH7	arginosuccinase
AWM71_03975	ENOG4105E5Q	amino acid AbC transporter
AWM71_03995	ENOG4105DAP	Nicotinate phosphoribosyltransferase
AWM71_04000	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
AWM71_04010	ENOG4105DQ6	Transposase
AWM71_04015	ENOG4105C8N	cysteinyl-tRNA synthetase
AWM71_04020	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AWM71_04025	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AWM71_04030	ENOG4105M0M	Tetracycline resistance protein
AWM71_04050	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AWM71_04065	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AWM71_04070	ENOG4108VZM	50s ribosomal protein L10
AWM71_04075	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AWM71_04080	ENOG4107Y49	methyltransferase
AWM71_04085	ENOG4105VUC	UPF0237 protein
AWM71_04090	ENOG4105CAG	UPF0210 protein
AWM71_04095	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AWM71_04100	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AWM71_04150	ENOG4105PGM	cation diffusion facilitator family transporter
AWM71_04155	ENOG4105KEX	transcriptional regulator, ctsr
AWM71_04160	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AWM71_04170	ENOG4108Z6B	deaminase
AWM71_04180	ENOG4105C6E	dna polymerase iii
AWM71_04185	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AWM71_04190	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AWM71_04195	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AWM71_04200	ENOG4105FA2	dna polymerase iii
AWM71_04210	ENOG41063V3	Involved in initiation control of chromosome replication (By similarity)
AWM71_04215	ENOG41060K3	Methyltransferase
AWM71_04220	ENOG4105VC4	domain protein
AWM71_04225	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
AWM71_04230	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AWM71_04235	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AWM71_04250	ENOG4105CHM	Aminotransferase
AWM71_04255	ENOG4105DCI	Phosphohydrolase
AWM71_04260	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
AWM71_04270	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
AWM71_04275	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AWM71_04280	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AWM71_04285	ENOG4108M60	Transcriptional regulator
AWM71_04295	ENOG41082DI	50s ribosomal protein l31
AWM71_04300	ENOG4108Z6X	(sortase) family
AWM71_04310	ENOG4105CPF	Cell wall formation (By similarity)
AWM71_04315	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
AWM71_04320	ENOG4105C1J	atp-dependent rna helicase
AWM71_04330	ENOG4105C37	(CBS) domain
AWM71_04360	ENOG4105DQ6	Transposase
AWM71_04390	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AWM71_04405	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AWM71_04410	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AWM71_04415	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AWM71_04420	ENOG4108JA2	transcriptioN-repair coupling factor
AWM71_04425	ENOG41082I2	s4 domain protein
AWM71_04435	ENOG41060GV	RNA binding s1 domain protein
AWM71_04440	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AWM71_04450	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AWM71_04455	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AWM71_04460	ENOG4105CRK	lysyL-tRNA synthetase
AWM71_04465	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AWM71_04470	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AWM71_04475	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AWM71_04480	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AWM71_04495	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AWM71_04500	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AWM71_04505	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AWM71_04510	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AWM71_04515	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AWM71_04520	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AWM71_04525	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AWM71_04530	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AWM71_04535	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AWM71_04540	ENOG41082SA	50s ribosomal protein l29
AWM71_04545	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AWM71_04550	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AWM71_04555	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AWM71_04560	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AWM71_04565	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AWM71_04570	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AWM71_04580	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AWM71_04585	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AWM71_04590	ENOG4105VPB	50S ribosomal protein L30
AWM71_04595	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AWM71_04600	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AWM71_04605	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AWM71_04610	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AWM71_04615	ENOG41067V7	50S ribosomal protein L36
AWM71_04620	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AWM71_04625	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AWM71_04630	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AWM71_04635	ENOG4108ZT0	50S ribosomal protein l17
AWM71_04640	ENOG4105EXC	Acyl-transferase
AWM71_04645	ENOG4108JJB	ABC transporter
AWM71_04650	ENOG4108JJB	ABC transporter
AWM71_04655	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
AWM71_04660	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AWM71_04665	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AWM71_04670	ENOG4108UJD	30S ribosomal protein S9
AWM71_04700	ENOG4105CSM	endonuclease III
AWM71_04710	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
AWM71_04725	ENOG4105DEN	Luciferase family
AWM71_04745	ENOG4108URH	decarboxylase
AWM71_04750	ENOG4105CMR	udp-glucose 4-epimerase
AWM71_04765	ENOG410902V	Modulates RecA activity (By similarity)
AWM71_04770	ENOG4105CEN	a g-specific adenine glycosylase
AWM71_04775	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AWM71_04780	ENOG4105EVI	UPF0374 protein
AWM71_04795	ENOG4105G5W	regulator Fur family
AWM71_04800	ENOG4105II7	pyrroline-5-carboxylate reductase
AWM71_04890	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AWM71_04895	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
AWM71_04900	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AWM71_04905	ENOG4105BZ4	penicillin-binding protein
AWM71_04910	ENOG4105WZB	UPF0342 protein
AWM71_04915	ENOG4107VRP	DNA repair exonuclease
AWM71_04920	ENOG4106D4I	domain protein
AWM71_04925	ENOG4105EQI	Metal Dependent Phosphohydrolase
AWM71_04930	ENOG4105W5Q	DNA repair protein (RadC
AWM71_04945	ENOG4107X35	defense response to bacterium
AWM71_04950	ENOG4105C2M	dna polymerase I
AWM71_04960	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AWM71_04975	ENOG4105C22	threonyL-tRNA synthetase
AWM71_04980	ENOG4105D1Z	hydroxypyruvate reductase
AWM71_04985	ENOG4105C6Z	Gluconate
AWM71_04995	ENOG4105K5M	30s ribosomal protein S16
AWM71_05000	ENOG4105VB6	UPF0109 protein
AWM71_05005	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AWM71_05010	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AWM71_05025	ENOG4108JJB	ABC transporter
AWM71_05030	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AWM71_05040	ENOG4108JJ9	ABC, transporter
AWM71_05045	ENOG4105BZ1	(ABC) transporter
AWM71_05050	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AWM71_05060	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AWM71_05075	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AWM71_05085	ENOG4105SFS	phosphoesterase RecJ domain protein
AWM71_05090	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
AWM71_05105	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AWM71_05115	ENOG4107RF6	penicillin-binding protein
AWM71_05125	ENOG4107ZXI	Rhomboid family
AWM71_05130	ENOG4105DKQ	ROK family
AWM71_05135	ENOG4105WZW	rhodanese family
AWM71_05140	ENOG4108VX5	3-methyladenine DNA glycosylase
AWM71_05145	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AWM71_05150	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AWM71_05155	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
AWM71_05165	ENOG4105K59	histidine triad (HIT) protein
AWM71_05180	ENOG4108V15	phosphotransferase enzyme family
AWM71_05195	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AWM71_05205	ENOG4105DFU	Cell wall formation (By similarity)
AWM71_05230	ENOG4105ETE	Transcriptional regulator (LacI family
AWM71_05235	ENOG4105DJV	ribulose-phosphate 3-epimerase
AWM71_05240	ENOG4108YZG	isomerase
AWM71_05245	ENOG4105C5Y	PTS System
AWM71_05255	ENOG4105CI1	PTS System
AWM71_05260	ENOG4105C8T	Leucyl-tRNA synthetase
AWM71_05285	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
AWM71_05290	ENOG4105FKQ	transcriptional regulator
AWM71_05295	ENOG4108IUK	alpha amylase, catalytic
AWM71_05300	ENOG4107FKK	extracellular solute-binding protein family 1
AWM71_05305	ENOG4105D56	permease protein
AWM71_05310	ENOG4105EG2	ABC transporter, permease
AWM71_05315	ENOG4108VP7	maltodextrose utilization protein MalA
AWM71_05320	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
AWM71_05325	ENOG4105CG3	alpha amylase, catalytic region
AWM71_05330	ENOG4108IJ9	(ABC) transporter
AWM71_05340	ENOG4107QSE	Dipeptidase
AWM71_05345	ENOG4108RWN	rrna methyltransferase
AWM71_05350	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AWM71_05355	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AWM71_05365	ENOG4108IJ2	phosphate acetyltransferase
AWM71_05370	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
AWM71_05385	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AWM71_05390	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AWM71_05395	ENOG4105E0X	reductase
AWM71_05400	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AWM71_05410	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AWM71_05415	ENOG4105C0B	DNA polymerase III (alpha subunit)
AWM71_05420	ENOG4105CTQ	phosphohexokinase
AWM71_05425	ENOG4105CA9	Pyruvate kinase
AWM71_05435	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AWM71_05440	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AWM71_05460	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AWM71_05465	ENOG4105CP9	extracellular ligand-binding receptor
AWM71_05470	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AWM71_05475	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
AWM71_05485	ENOG4105DMS	mur ligase
AWM71_05490	ENOG4105F1K	Glutamine amidotransferase
AWM71_05495	ENOG4107104	thymidine kinase
AWM71_05505	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AWM71_05510	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AWM71_05515	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AWM71_05520	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AWM71_05525	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
AWM71_05530	ENOG410855V	Acylphosphatase
AWM71_05540	ENOG4105CN9	Peptidase m42 family protein
AWM71_05550	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AWM71_05555	ENOG4105CEV	competence damage-inducible protein
AWM71_05570	ENOG4108UIC	UPF0340 protein
AWM71_05590	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
AWM71_05595	ENOG4105C31	Tryptophanyl-tRNA synthetase
AWM71_05620	ENOG4105EMS	pseudouridine synthase
AWM71_05665	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
AWM71_05670	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
AWM71_05725	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AWM71_05730	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AWM71_05740	ENOG4105MU5	relaxase mobilization nuclease domain protein
AWM71_05790	ENOG4108MRH	transcriptional regulatory protein
AWM71_05800	ENOG4105C5I	Dehydrogenase
AWM71_05815	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AWM71_05820	ENOG4105KRI	phosphocarrier protein (HPr
AWM71_05825	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AWM71_05840	ENOG4105BZF	Glycosyl transferase (Group 1
AWM71_05850	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AWM71_05855	ENOG4105D6E	homoserine dehydrogenase
AWM71_05860	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AWM71_05865	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
AWM71_05870	ENOG4105CQW	ribosome biogenesis GTPase YqeH
AWM71_05875	ENOG410812S	Rna-binding protein
AWM71_05880	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AWM71_05885	ENOG4108WF2	Metal Dependent Phosphohydrolase
AWM71_05890	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
AWM71_05895	ENOG4105DXX	methyltransferase
AWM71_05910	ENOG41067VY	50S ribosomal protein L32
AWM71_05920	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AWM71_05930	ENOG4108RYC	glycosyltransferase
AWM71_05945	ENOG4105C98	muts2 protein
AWM71_05950	ENOG4105K63	Thioredoxin
AWM71_05960	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AWM71_05975	ENOG4105DVE	abc transporter atp-binding protein
AWM71_05985	ENOG4105HMD	
AWM71_05990	ENOG4105D8X	mechanosensitive ion channel
AWM71_06005	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AWM71_06020	ENOG4105ETZ	PTS System
AWM71_06035	ENOG410667J	hydrolase
AWM71_06045	ENOG4105CDY	transcriptional regulatory protein
AWM71_06050	ENOG4105CTZ	aminopeptidase c
AWM71_06060	ENOG4106EHS	UPF0356 protein
AWM71_06065	ENOG4105W8X	HesB YadR YfhF-family protein
AWM71_06075	ENOG4105CS9	pantothenic acid kinase
AWM71_06080	ENOG4105C02	permease
AWM71_06090	ENOG4105BZ1	(ABC) transporter
AWM71_06100	ENOG4105C5H	ABC transporter
AWM71_06105	ENOG4107YBY	Hydrolase
AWM71_06110	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AWM71_06115	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AWM71_06120	ENOG4105DWF	phosphomethylpyrimidine kinase
AWM71_06125	ENOG4105ETU	transcriptional activator (TenA
AWM71_06140	ENOG4108W7F	transporter, permease
AWM71_06145	ENOG4108JJB	ABC transporter
AWM71_06150	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
AWM71_06155	ENOG4105KJF	protein tyrosine phosphatase
AWM71_06165	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AWM71_06175	ENOG4105BZ4	penicillin-binding protein
AWM71_06180	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
AWM71_06185	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AWM71_06190	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AWM71_06200	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AWM71_06205	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AWM71_06210	ENOG4105CFH	Aspartokinase
AWM71_06235	ENOG41060M0	Crispr-associated protein, cse4 family
AWM71_06250	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
AWM71_06255	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
AWM71_06290	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
AWM71_06310	ENOG4105CHR	reductase
AWM71_06325	ENOG410906U	SprT-like
AWM71_06330	ENOG4106P55	Transcriptional regulator
AWM71_06340	ENOG4105CKM	Branched-chain carboxylic acid kinase
AWM71_06355	ENOG4105CPP	Dehydrogenase, E1 component
AWM71_06360	ENOG4105C7S	Dehydrogenase
AWM71_06370	ENOG4105E5Q	amino acid AbC transporter
AWM71_06375	ENOG4105CDA	abc transporter atp-binding protein
AWM71_06400	ENOG4105E5Q	amino acid AbC transporter
AWM71_06405	ENOG4105CDA	abc transporter atp-binding protein
AWM71_06420	ENOG4105CXT	aspartate transcarbamylase
AWM71_06425	ENOG4105CD3	dihydroorotase
AWM71_06430	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
AWM71_06445	ENOG4105K46	50S ribosomal protein l27
AWM71_06470	ENOG4105DQ6	Transposase
AWM71_06490	ENOG4105BZ1	(ABC) transporter
AWM71_06500	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AWM71_06505	ENOG4105F38	ABC transporter, permease
AWM71_06510	ENOG4105D38	putrescine abc transporter
AWM71_06515	ENOG4107RUE	extracellular solute-binding protein family 1
AWM71_06595	ENOG4108IUX	(ABC) transporter
AWM71_06615	ENOG4105C5I	Dehydrogenase
AWM71_06620	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
AWM71_06635	ENOG4105D06	uba thif-type nad fad binding protein
AWM71_06640	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AWM71_06670	ENOG4105CK1	PTS System
AWM71_06675	ENOG4105VZJ	PTS System
AWM71_06680	ENOG4105VCP	PTS System
AWM71_06700	ENOG4105VTR	Integrase
AWM71_06820	ENOG4105E98	transcriptional regulator DeoR family
AWM71_06835	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AWM71_06840	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AWM71_06845	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AWM71_06855	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AWM71_06860	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AWM71_06865	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AWM71_06880	ENOG4105D1H	recombination factor protein RarA
AWM71_06885	ENOG4107QI6	Cysteine desulfurase
AWM71_06900	ENOG4105C7H	Helicase, RecD TraA family
AWM71_06910	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AWM71_06920	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AWM71_06925	ENOG4105VPH	UPF0473 protein
AWM71_06955	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AWM71_06960	ENOG4105CE9	30S ribosomal protein S2
AWM71_06965	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AWM71_06970	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AWM71_06975	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AWM71_06980	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AWM71_06985	ENOG4105KNE	Phosphatidate cytidylyltransferase
AWM71_06990	ENOG4105DZP	Membrane-associated zinc metalloprotease
AWM71_06995	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
AWM71_07000	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AWM71_07010	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
AWM71_07020	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AWM71_07050	ENOG4105D1Q	UPF0246 protein
AWM71_07055	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AWM71_07065	ENOG4108RYM	conjugative transposon protein
AWM71_07075	ENOG4106BHR	ftsk SpoIIIE family protein
AWM71_07080	ENOG4106128	DNA-binding helix-turn-helix protein
AWM71_07110	ENOG4105K4H	Nlp p60 protein
AWM71_07150	ENOG410807C	QueT transporter
AWM71_07155	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AWM71_07160	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AWM71_07165	ENOG4105DTN	riboflavin biosynthesis protein ribF
AWM71_07185	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AWM71_07190	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AWM71_07195	ENOG4105CFG	Acts as a chaperone (By similarity)
AWM71_07200	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AWM71_07215	ENOG4105CKU	formyltetrahydrofolate synthetase
AWM71_07220	ENOG4105C5H	ABC transporter
AWM71_07255	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
AWM71_07260	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AWM71_07265	ENOG4105C79	DNA protecting protein DprA
AWM71_07270	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AWM71_07275	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AWM71_07280	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
AWM71_07285	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
AWM71_07290	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AWM71_07295	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AWM71_07300	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
AWM71_07335	ENOG4105CY2	Citrate transporter
AWM71_07355	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AWM71_07385	ENOG4108M3J	Dehydrogenase
AWM71_07425	ENOG4105CHR	reductase
AWM71_07430	ENOG4107Z6I	Thiamine biosynthesis protein
AWM71_07435	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
AWM71_07470	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AWM71_07480	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
AWM71_07505	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AWM71_07535	ENOG4105C5X	domain protein
AWM71_07560	ENOG4107YZX	Universal stress protein
AWM71_07565	ENOG4105CSM	endonuclease III
AWM71_07570	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AWM71_07575	ENOG4108Z66	YbaK ebsC protein
AWM71_07580	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AWM71_07585	ENOG4105D82	Glutamate dehydrogenase
AWM71_07590	ENOG4108UK2	deaminase
AWM71_07600	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AWM71_07610	ENOG4105RHA	ABC transporter, permease
AWM71_07615	ENOG4105F23	Fibronectin-binding protein
AWM71_07620	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AWM71_07625	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AWM71_07630	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AWM71_07645	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AWM71_07650	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
AWM71_07655	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
AWM71_07660	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AWM71_07670	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AWM71_07675	ENOG4105C9A	Phoh family
AWM71_07680	ENOG4105KTH	gatB Yqey
AWM71_07685	ENOG4105VCC	30S ribosomal protein S21
AWM71_07695	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
AWM71_07700	ENOG4105N80	Ferric uptake regulator, Fur family
AWM71_07705	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AWM71_07725	ENOG4105D07	Signal peptide peptidase, SppA
AWM71_07730	ENOG4105C9M	aspartyl-trna synthetase
AWM71_07735	ENOG4105CUT	histidyl-tRNA synthetase
AWM71_07780	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AWM71_07785	ENOG4105RNB	
AWM71_07795	ENOG41067VY	50S ribosomal protein L32