locus-tag	class	description
AWM72_00015	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AWM72_00120	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
AWM72_00145	ENOG4105VTR	Integrase
AWM72_00160	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
AWM72_00170	ENOG41082R7	4-amino-4-deoxychorismate lyase EC 4.1.3.38
AWM72_00180	ENOG4105DDQ	anthranilate synthase
AWM72_00200	ENOG4105EE1	crotonyl-CoA reductase
AWM72_00235	ENOG4105ESP	cell wall surface anchor family protein
AWM72_00250	ENOG4105C75	arginyL-tRNA synthetase
AWM72_00255	ENOG4105C5B	carbamate kinase
AWM72_00260	ENOG4107QSE	Dipeptidase
AWM72_00265	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
AWM72_00275	ENOG4105CEU	Arginine dihydrolase
AWM72_00305	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AWM72_00310	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AWM72_00315	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AWM72_00320	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AWM72_00325	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AWM72_00330	ENOG4107104	thymidine kinase
AWM72_00335	ENOG4105DMS	mur ligase
AWM72_00340	ENOG4105F1K	Glutamine amidotransferase
AWM72_00350	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
AWM72_00355	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AWM72_00360	ENOG4105CFH	Aspartokinase
AWM72_00365	ENOG4105CH2	amidohydrolase
AWM72_00370	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
AWM72_00380	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AWM72_00385	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AWM72_00430	ENOG4105C75	arginyL-tRNA synthetase
AWM72_00435	ENOG4105C9K	Endothelin-converting enzyme 1
AWM72_00455	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AWM72_00470	ENOG4105DIW	FeS assembly protein SUFB
AWM72_00475	ENOG4108UNV	SUF system FeS assembly protein, NifU family
AWM72_00480	ENOG4105C9B	Cysteine desulfurase
AWM72_00485	ENOG4105JRK	feS assembly protein SufD
AWM72_00500	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AWM72_00505	ENOG4105CHU	acetyl-coa acetyltransferase
AWM72_00510	ENOG4105EA8	2-Nitropropane dioxygenase
AWM72_00520	ENOG4105CNI	cell division protein FtsW
AWM72_00535	ENOG4105D01	(LipO)protein
AWM72_00540	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AWM72_00550	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AWM72_00565	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AWM72_00570	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AWM72_00575	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AWM72_00580	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AWM72_00590	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
AWM72_00595	ENOG4105BZ4	penicillin-binding protein
AWM72_00600	ENOG4105DPH	UPF0371 protein
AWM72_00610	ENOG4105NA0	Transcriptional regulator
AWM72_00615	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AWM72_00620	ENOG410667J	hydrolase
AWM72_00625	ENOG4107ZCW	Low molecular weight phosphotyrosine protein phosphatase
AWM72_00630	ENOG4108UIC	UPF0340 protein
AWM72_00640	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
AWM72_00650	ENOG4105DRS	transport system, permease
AWM72_00665	ENOG4107R33	ppx gppa phosphatase
AWM72_00670	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AWM72_00675	ENOG4105C5H	ABC transporter
AWM72_00680	ENOG4105CS9	pantothenic acid kinase
AWM72_00690	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AWM72_00695	ENOG4108UT2	hemolysin iii
AWM72_00700	ENOG4106EHS	UPF0356 protein
AWM72_00705	ENOG4105CN5	Metallo-Beta-Lactamase
AWM72_00710	ENOG4105WH1	Two component transcriptional regulator luxr family
AWM72_00715	ENOG4105ENE	Histidine kinase
AWM72_00730	ENOG4105DBI	uridine monophosphokinase
AWM72_00745	ENOG4105VPH	UPF0473 protein
AWM72_00760	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AWM72_00765	ENOG4105C7H	Helicase, RecD TraA family
AWM72_00770	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AWM72_00785	ENOG4105C3J	Cysteine desulfurase
AWM72_00790	ENOG4105D9M	gamma-glutamylcysteine synthetase
AWM72_00795	ENOG4105D1H	recombination factor protein RarA
AWM72_00810	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AWM72_00820	ENOG4105K46	50S ribosomal protein l27
AWM72_00825	ENOG4105X36	(ribosomal) protein
AWM72_00855	ENOG4107QSA	Oxaloacetate decarboxylase
AWM72_00870	ENOG4105D9Q	decarboxylase (Beta subunit)
AWM72_00875	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
AWM72_00885	ENOG4105D4T	Citrate transporter
AWM72_00890	ENOG4105C5Y	PTS System
AWM72_00895	ENOG4105CDA	abc transporter atp-binding protein
AWM72_00900	ENOG4105E5Q	amino acid AbC transporter
AWM72_00910	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AWM72_01045	ENOG4107QYV	phosphohexose isomerase
AWM72_01055	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AWM72_01080	ENOG4105MMD	transcriptional regulator
AWM72_01105	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
AWM72_01110	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AWM72_01115	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AWM72_01125	ENOG4105K70	DNA-binding protein
AWM72_01130	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AWM72_01135	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AWM72_01140	ENOG4105CAT	Cytidine monophosphate kinase
AWM72_01150	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AWM72_01170	ENOG4105FE9	pseudouridine synthase
AWM72_01175	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AWM72_01180	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
AWM72_01190	ENOG4105X1N	Glycosyl transferase family 8
AWM72_01200	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AWM72_01215	ENOG4105I3K	Ferric uptake regulator, Fur family
AWM72_01220	ENOG4105QNR	S1 RNA binding domain protein
AWM72_01225	ENOG4105CA9	Pyruvate kinase
AWM72_01230	ENOG4105CTQ	phosphohexokinase
AWM72_01235	ENOG4105C0B	DNA polymerase III (alpha subunit)
AWM72_01240	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AWM72_01255	ENOG4105E0X	reductase
AWM72_01265	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AWM72_01295	ENOG4107FQX	Alpha-acetolactate decarboxylase
AWM72_01300	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
AWM72_01305	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AWM72_01310	ENOG4105CEV	competence damage-inducible protein
AWM72_01315	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AWM72_01320	ENOG4105CNU	cell division protein FtsK
AWM72_01325	ENOG410855V	Acylphosphatase
AWM72_01330	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
AWM72_01335	ENOG4105GR3	Histidine kinase
AWM72_01340	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AWM72_01345	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
AWM72_01350	ENOG4105C3J	Cysteine desulfurase
AWM72_01355	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
AWM72_01360	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AWM72_01385	ENOG4105CDW	Resistance protein
AWM72_01400	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AWM72_01410	ENOG4105DBK	s4 domain protein
AWM72_01420	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
AWM72_01425	ENOG4105DFA	alanine racemase domain protein
AWM72_01430	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AWM72_01435	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AWM72_01440	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
AWM72_01445	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AWM72_01455	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AWM72_01460	ENOG4105CJN	penicillin-binding protein
AWM72_01470	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AWM72_01475	ENOG4108V6E	Cell division protein mraZ
AWM72_01490	ENOG4105CDE	UPF0348 protein
AWM72_01495	ENOG4105DXX	methyltransferase
AWM72_01500	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
AWM72_01505	ENOG4108WF2	Metal Dependent Phosphohydrolase
AWM72_01510	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AWM72_01515	ENOG410812S	Rna-binding protein
AWM72_01520	ENOG4105CQW	ribosome biogenesis GTPase YqeH
AWM72_01540	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AWM72_01550	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AWM72_01565	ENOG4105HDK	L-asparaginase
AWM72_01595	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AWM72_01600	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AWM72_01610	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AWM72_01615	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AWM72_01630	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AWM72_01645	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AWM72_01650	ENOG4105KWG	Pfam:DUF1696
AWM72_01655	ENOG4105VDH	Dihydroxyacetone kinase
AWM72_01660	ENOG4108UTZ	Dihydroxyacetone kinase
AWM72_01665	ENOG4105CMT	Dihydroxyacetone kinase
AWM72_01675	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AWM72_01680	ENOG4105PAD	Hydrolase
AWM72_01685	ENOG4105CP7	Triose-phosphate isomerase
AWM72_01700	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AWM72_01705	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AWM72_01725	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
AWM72_01730	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AWM72_01735	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AWM72_01740	ENOG4105VB6	UPF0109 protein
AWM72_01745	ENOG4105K5M	30s ribosomal protein S16
AWM72_01755	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
AWM72_01760	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AWM72_01765	ENOG410667J	hydrolase
AWM72_01770	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AWM72_01775	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AWM72_01780	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AWM72_01790	ENOG4105CB5	ATP-dependent DNA helicase recG
AWM72_01795	ENOG4105DEN	Luciferase family
AWM72_01805	ENOG4108ZAA	Alkaline-shock protein
AWM72_01810	ENOG4105C59	p-type ATPase
AWM72_01815	ENOG4105VB9	50S ribosomal protein l28
AWM72_01825	ENOG4105DJV	ribulose-phosphate 3-epimerase
AWM72_01830	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AWM72_01835	ENOG4105D9P	serine threonine protein kinase
AWM72_01845	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AWM72_01850	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AWM72_01855	ENOG4105C25	Primosomal protein n'
AWM72_01860	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AWM72_01875	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AWM72_01890	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AWM72_01905	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AWM72_01910	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AWM72_01915	ENOG4105EPR	degv family
AWM72_01920	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
AWM72_01925	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AWM72_01930	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AWM72_01935	ENOG4105MZU	cell filamentation protein
AWM72_01940	ENOG4105TQK	DNA polymerase iii, delta' subunit
AWM72_01950	ENOG4105KQC	Competence protein
AWM72_01955	ENOG4106H78	methyltransferase
AWM72_02075	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
AWM72_02080	ENOG4105CNI	cell division protein FtsW
AWM72_02085	ENOG4105ZPI	UPF0358 protein
AWM72_02090	ENOG4105CI3	gtp-binding protein typa
AWM72_02095	ENOG4105ECY	inositol monophosphatase
AWM72_02110	ENOG4105C7S	Dehydrogenase
AWM72_02115	ENOG4105CPP	Dehydrogenase, E1 component
AWM72_02125	ENOG4107YB9	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AWM72_02130	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AWM72_02140	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AWM72_02150	ENOG4105C7B	Threonine dehydratase
AWM72_02160	ENOG4108ZP8	Acetolactate synthase small subunit
AWM72_02170	ENOG4105DKW	ABC transporter
AWM72_02175	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AWM72_02180	ENOG4105D98	threonine synthase
AWM72_02195	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
AWM72_02210	ENOG4105D2H	Uronic isomerase
AWM72_02220	ENOG4108UHU	Aldolase
AWM72_02230	ENOG4105DMW	Dehydrogenase reductase
AWM72_02240	ENOG4107QSE	Dipeptidase
AWM72_02250	ENOG4105DC7	peptidase M24
AWM72_02260	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AWM72_02265	ENOG4105KJF	protein tyrosine phosphatase
AWM72_02270	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AWM72_02275	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AWM72_02285	ENOG4105CHR	reductase
AWM72_02305	ENOG4108VXD	carboxy-peptidase
AWM72_02310	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AWM72_02315	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AWM72_02320	ENOG4105C09	Bile acid
AWM72_02340	ENOG4105DDQ	anthranilate synthase
AWM72_02345	ENOG4105CRQ	synthase (Component I)
AWM72_02355	ENOG4105RNB	
AWM72_02370	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AWM72_02375	ENOG4105ST3	Transcriptional regulator
AWM72_02410	ENOG4105HMD	
AWM72_02415	ENOG4105C72	UPF0176 protein
AWM72_02430	ENOG4105K5X	acetyltransferase
AWM72_02450	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AWM72_02505	ENOG4105QZI	O-Antigen Polymerase
AWM72_02510	ENOG4108KMV	Glycosyl transferase (Group 1
AWM72_02520	ENOG4105CPK	Glycosyl transferase (Group 1
AWM72_02545	ENOG4108R85	Short chain dehydrogenase
AWM72_02550	ENOG4105DND	Transcriptional regulator
AWM72_02610	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AWM72_02625	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
AWM72_02695	ENOG4105E5Q	amino acid AbC transporter
AWM72_02700	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AWM72_02720	ENOG4105FDK	ABC transporter
AWM72_02725	ENOG4105DSE	periplasmic solute binding protein
AWM72_02730	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AWM72_02735	ENOG4105W42	Veg protein
AWM72_02740	ENOG4105CG9	aspartate racemase
AWM72_02750	ENOG4105CAQ	asparagine synthetase
AWM72_02755	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AWM72_02760	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
AWM72_02765	ENOG4105F8V	Hydrolase, tatD family
AWM72_02770	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AWM72_02785	ENOG4105CHM	Aminotransferase
AWM72_02790	ENOG4105C5F	glutamine synthetase
AWM72_02800	ENOG4105C5F	glutamine synthetase
AWM72_02830	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AWM72_02835	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AWM72_02840	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AWM72_02845	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AWM72_02855	ENOG4107RBD	ABC, transporter
AWM72_02860	ENOG4105CC5	ABC transporter
AWM72_02865	ENOG4105DIK	(ABC) transporter
AWM72_02870	ENOG4105DSE	periplasmic solute binding protein
AWM72_02885	ENOG4105CMR	udp-glucose 4-epimerase
AWM72_02890	ENOG4105C34	Pseudouridine synthase
AWM72_02895	ENOG4105D82	Glutamate dehydrogenase
AWM72_02905	ENOG410807C	QueT transporter
AWM72_02930	ENOG4105GH9	galactofuranosyltransferase
AWM72_02935	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
AWM72_02940	ENOG4105D01	(LipO)protein
AWM72_02945	ENOG4105D01	(LipO)protein
AWM72_02950	ENOG4105D01	(LipO)protein
AWM72_02955	ENOG4108K88	Membrane
AWM72_02980	ENOG4105CJ1	ABC, transporter
AWM72_02995	ENOG41061MV	Arylsulfatase
AWM72_03015	ENOG4108UJD	30S ribosomal protein S9
AWM72_03020	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AWM72_03025	ENOG4105C4W	S-formylglutathione hydrolase
AWM72_03035	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AWM72_03040	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AWM72_03050	ENOG4108JJB	ABC transporter
AWM72_03055	ENOG4108JJB	ABC transporter
AWM72_03060	ENOG4105EXC	Acyl-transferase
AWM72_03065	ENOG4108ZT0	50S ribosomal protein l17
AWM72_03070	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AWM72_03075	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AWM72_03090	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AWM72_03095	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AWM72_03100	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AWM72_03105	ENOG4105VPB	50S ribosomal protein L30
AWM72_03110	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AWM72_03115	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AWM72_03120	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AWM72_03125	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AWM72_03130	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AWM72_03135	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AWM72_03145	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AWM72_03150	ENOG41082SA	50s ribosomal protein l29
AWM72_03155	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AWM72_03160	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AWM72_03165	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AWM72_03170	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AWM72_03175	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AWM72_03180	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AWM72_03185	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AWM72_03190	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AWM72_03195	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AWM72_03200	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
AWM72_03205	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
AWM72_03225	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AWM72_03235	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AWM72_03240	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AWM72_03245	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AWM72_03250	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AWM72_03255	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AWM72_03270	ENOG4105CRK	lysyL-tRNA synthetase
AWM72_03275	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AWM72_03280	ENOG4105C6T	cysteine synthase
AWM72_03285	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AWM72_03290	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AWM72_03295	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AWM72_03300	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AWM72_03305	ENOG41060GV	RNA binding s1 domain protein
AWM72_03315	ENOG41082I2	s4 domain protein
AWM72_03325	ENOG4108JA2	transcriptioN-repair coupling factor
AWM72_03330	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AWM72_03335	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AWM72_03345	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AWM72_03350	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AWM72_03355	ENOG4105FDU	atp-dependent rna helicase
AWM72_03365	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AWM72_03390	ENOG4105KME	endoribonuclease L-psp
AWM72_03405	ENOG4105CKK	Glycosyl transferase, family 2
AWM72_03445	ENOG4108VQJ	O-methyltransferase
AWM72_03450	ENOG4105C37	(CBS) domain
AWM72_03455	ENOG4105D17	glycoside hydrolase, family 3 domain protein
AWM72_03465	ENOG4106PMH	Extracellular solute-binding protein family 3
AWM72_03470	ENOG4105CDA	abc transporter atp-binding protein
AWM72_03475	ENOG4105E5Q	amino acid AbC transporter
AWM72_03480	ENOG4105DRP	amino acid AbC transporter
AWM72_03490	ENOG4105VG1	fes assembly suf system protein
AWM72_03495	ENOG4107UWA	esterase
AWM72_03505	ENOG4105DG6	mannose-6-phosphate isomerase
AWM72_03515	ENOG4105F3R	pts system mannose fructose sorbose family iid
AWM72_03520	ENOG4105ETZ	PTS System
AWM72_03545	ENOG4107PP3	Acetylornithine deacetylase
AWM72_03570	ENOG4105C59	p-type ATPase
AWM72_03575	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
AWM72_03590	ENOG4105J7I	hydrolase
AWM72_03595	ENOG4105DFM	M18 family aminopeptidase
AWM72_03605	ENOG4105ETE	Transcriptional regulator (LacI family
AWM72_03610	ENOG4108HKT	sucrose-6-phosphate hydrolase
AWM72_03615	ENOG4105C5Y	PTS System
AWM72_03620	ENOG4105EVU	fructokinase
AWM72_03630	ENOG4105DVE	abc transporter atp-binding protein
AWM72_03640	ENOG4105D01	(LipO)protein
AWM72_03645	ENOG4105C6Z	Gluconate
AWM72_03650	ENOG4105G63	Type III effector Hrp-dependent
AWM72_03660	ENOG4105E98	transcriptional regulator DeoR family
AWM72_03665	ENOG4108JU6	CBS domain protein
AWM72_03680	ENOG4105BZ1	(ABC) transporter
AWM72_03685	ENOG4105BZ1	(ABC) transporter
AWM72_03690	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
AWM72_03695	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AWM72_03705	ENOG4108MXZ	Esterase
AWM72_03710	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AWM72_03715	ENOG4105CTP	PilT protein domain protein
AWM72_03720	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AWM72_03725	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AWM72_03730	ENOG4105CGH	5'-nucleotidase
AWM72_03745	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AWM72_03765	ENOG4108REF	Sporulation integral membrane protein ytvi
AWM72_03775	ENOG4105KV4	Transcriptional regulator
AWM72_03785	ENOG4105C87	Aminotransferase class I and II
AWM72_03795	ENOG4105BZF	Glycosyl transferase (Group 1
AWM72_03800	ENOG4105C01	Dihydroxy-acid dehydratase
AWM72_03810	ENOG4105CG3	alpha amylase, catalytic region
AWM72_03815	ENOG4105C5Y	PTS System
AWM72_03840	ENOG4105E6M	Sulphatase-modifying factor protein
AWM72_03880	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
AWM72_03890	ENOG4105SYT	Methylenetetrahydrofolate reductase
AWM72_03895	ENOG4105C83	adenylosuccinate lyase
AWM72_03905	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AWM72_03910	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AWM72_03915	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AWM72_03920	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AWM72_03925	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AWM72_03930	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
AWM72_03935	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
AWM72_03940	ENOG4105C8V	SAICAR synthetase
AWM72_03945	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AWM72_03950	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AWM72_03960	ENOG4105C83	adenylosuccinate lyase
AWM72_03965	ENOG4105CJW	magnesium transporter
AWM72_03970	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AWM72_04010	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AWM72_04040	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AWM72_04045	ENOG4105CDU	Replicative dna helicase
AWM72_04050	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AWM72_04060	ENOG4108UUM	single-stranded DNA-binding protein
AWM72_04065	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AWM72_04080	ENOG4105BZ1	(ABC) transporter
AWM72_04095	ENOG4108IUX	(ABC) transporter
AWM72_04100	ENOG4105RHA	ABC transporter, permease
AWM72_04105	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AWM72_04110	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AWM72_04115	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AWM72_04120	ENOG410848D	S4 domain protein YaaA
AWM72_04135	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AWM72_04145	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AWM72_04150	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AWM72_04160	ENOG4107STF	Involved in phosphonate degradation (By similarity)
AWM72_04165	ENOG4107STF	Involved in phosphonate degradation (By similarity)
AWM72_04180	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AWM72_04185	ENOG4105E98	transcriptional regulator DeoR family
AWM72_04190	ENOG4105TRI	Hydrolase
AWM72_04195	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AWM72_04200	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AWM72_04230	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
AWM72_04240	ENOG4107QJE	Chromosome Partitioning Protein
AWM72_04245	ENOG4105FA0	parb-like partition protein
AWM72_04250	ENOG4105VDK	protein, conserved in bacteria
AWM72_04255	ENOG4105C3G	gtp-binding protein
AWM72_04270	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AWM72_04275	ENOG4107R7Y	intracellular protease Pfpi family
AWM72_04300	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AWM72_04305	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AWM72_04350	ENOG4105C28	cystathionine
AWM72_04360	ENOG4105CIG	ABC transporter
AWM72_04390	ENOG4107YZX	Universal stress protein
AWM72_04410	ENOG4105VBF	alkaline shock protein
AWM72_04415	ENOG4108Z0Z	intracellular protease Pfpi family
AWM72_04420	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AWM72_04425	ENOG4105BZ1	(ABC) transporter
AWM72_04430	ENOG4105BZ1	(ABC) transporter
AWM72_04435	ENOG4105CFP	Peptidase U32
AWM72_04440	ENOG4105XYU	peptidase (U32 family)
AWM72_04450	ENOG4107RGD	Major Facilitator superfamily
AWM72_04455	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AWM72_04460	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AWM72_04465	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AWM72_04515	ENOG4105DY9	regulatoR
AWM72_04530	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
AWM72_04535	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AWM72_04545	ENOG4105K8R	UPF0145 protein
AWM72_04550	ENOG4105DHI	Methyltransferase
AWM72_04555	ENOG4105K78	MarR family Transcriptional regulator
AWM72_04570	ENOG4105C7N	Xanthine uracil vitamin C permease
AWM72_04585	ENOG410667J	hydrolase
AWM72_04590	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AWM72_04600	ENOG4108S4H	thioesterase Superfamily protein
AWM72_04605	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AWM72_04610	ENOG4105VI0	Pts system, glucitol sorbitol-specific
AWM72_04615	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AWM72_04625	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AWM72_04630	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AWM72_04635	ENOG4105C02	permease
AWM72_04640	ENOG4105CTZ	aminopeptidase c
AWM72_04665	ENOG4105C8N	cysteinyl-tRNA synthetase
AWM72_04670	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AWM72_04675	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AWM72_04705	ENOG4108WCX	response regulator
AWM72_04740	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AWM72_04750	ENOG4105DSE	periplasmic solute binding protein
AWM72_04760	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AWM72_04765	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AWM72_04780	ENOG4108UQV	Membrane
AWM72_04785	ENOG4108VZM	50s ribosomal protein L10
AWM72_04790	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AWM72_04805	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AWM72_04810	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
AWM72_04815	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AWM72_04820	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AWM72_04835	ENOG4105DQ4	alcohol dehydrogenase
AWM72_04845	ENOG4107Y49	methyltransferase
AWM72_04850	ENOG4108TVJ	Nitroreductase
AWM72_04855	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AWM72_04860	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AWM72_04870	ENOG41083J0	(ABC) transporter
AWM72_04875	ENOG4105C4B	ABC transporter, permease
AWM72_04915	ENOG4105D9N	nucleoside
AWM72_04925	ENOG4105KEX	transcriptional regulator, ctsr
AWM72_04930	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AWM72_04940	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AWM72_04950	ENOG4108Z6B	deaminase
AWM72_04990	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
AWM72_05015	ENOG4108JCD	RNA Polymerase
AWM72_05025	ENOG4105CCS	Glutamate formiminotransferase
AWM72_05030	ENOG4107QQ0	gntp family
AWM72_05035	ENOG4105BZW	Glycerate kinase
AWM72_05045	ENOG4107EFR	Flavocytochrome c
AWM72_05050	ENOG4105CY2	Citrate transporter
AWM72_05075	ENOG4105MUN	Divergent AAA domain
AWM72_05085	ENOG4107QMH	DNA methylase
AWM72_05100	ENOG4105DEF	Extracellular solute-binding protein, family 5
AWM72_05110	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AWM72_05115	ENOG4105C3U	ABC transporter
AWM72_05120	ENOG4108JQ7	(ABC) transporter
AWM72_05125	ENOG4105DSE	periplasmic solute binding protein
AWM72_05130	ENOG4105D01	(LipO)protein
AWM72_05135	ENOG4105DBV	ornithine carbamoyltransferase
AWM72_05170	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AWM72_05175	ENOG4105DC8	reductase
AWM72_05190	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
AWM72_05195	ENOG4105C6E	dna polymerase iii
AWM72_05200	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AWM72_05205	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AWM72_05210	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AWM72_05215	ENOG4105FA2	dna polymerase iii
AWM72_05225	ENOG41063V3	Involved in initiation control of chromosome replication (By similarity)
AWM72_05230	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
AWM72_05235	ENOG4105VC4	domain protein
AWM72_05240	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
AWM72_05250	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AWM72_05255	ENOG4107VFR	oxidoreductase
AWM72_05275	ENOG4108UZ3	Transporter
AWM72_05280	ENOG4105DCI	Phosphohydrolase
AWM72_05285	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
AWM72_05295	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
AWM72_05300	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AWM72_05305	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AWM72_05310	ENOG41082DI	50s ribosomal protein l31
AWM72_05315	ENOG4107R11	Transcriptional regulator
AWM72_05340	ENOG4105CPF	Cell wall formation (By similarity)
AWM72_05345	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
AWM72_05350	ENOG4105C1J	atp-dependent rna helicase
AWM72_05355	ENOG4107ZSJ	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
AWM72_05380	ENOG4108U5N	UPF0316 protein
AWM72_05395	ENOG4105CT4	transporter
AWM72_05400	ENOG4105CT4	transporter
AWM72_05405	ENOG4105VPS	UPF0291 protein
AWM72_05420	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AWM72_05425	ENOG41072GX	Peptidase M22 Glycoprotease
AWM72_05435	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
AWM72_05440	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AWM72_05445	ENOG4105C5H	ABC transporter
AWM72_05455	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
AWM72_05465	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AWM72_05470	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AWM72_05475	ENOG4108YYH	Nadph-dependent fmn reductase
AWM72_05480	ENOG4105C26	Dehydrogenase
AWM72_05485	ENOG4105CH7	arginosuccinase
AWM72_05495	ENOG4105E5Q	amino acid AbC transporter
AWM72_05510	ENOG4105DAP	Nicotinate phosphoribosyltransferase
AWM72_05515	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
AWM72_05525	ENOG4105DY9	regulatoR
AWM72_05530	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
AWM72_05535	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
AWM72_05540	ENOG4105FKQ	transcriptional regulator
AWM72_05545	ENOG4105CI1	PTS System
AWM72_05555	ENOG4108YZG	isomerase
AWM72_05565	ENOG4105DFT	pur operon repressor
AWM72_05595	ENOG41060M0	Crispr-associated protein, cse4 family
AWM72_05610	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
AWM72_05615	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
AWM72_05630	ENOG4105C88	aminopeptidase
AWM72_05635	ENOG4105NQC	Flavodoxin
AWM72_05655	ENOG4108RVA	ribokinase
AWM72_05665	ENOG4105CI1	PTS System
AWM72_05670	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AWM72_05690	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AWM72_05695	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AWM72_05700	ENOG4105BZU	Histidine kinase
AWM72_05705	ENOG4107S17	Phosphate-binding protein
AWM72_05710	ENOG4105C8U	phosphate abc transporter
AWM72_05715	ENOG4105E2Z	phosphate ABC transporter (Permease
AWM72_05720	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AWM72_05725	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AWM72_05730	ENOG4107RFY	SbcCD D subunit
AWM72_05750	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
AWM72_05755	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AWM72_05760	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AWM72_05765	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AWM72_05770	ENOG4105C3M	thioredoxin reductase
AWM72_05780	ENOG4105EPR	degv family
AWM72_05785	ENOG4108Z4K	mutator MutT protein
AWM72_05795	ENOG4105HTX	biosynthesis protein
AWM72_05800	ENOG4108QV3	biosynthesis protein
AWM72_05810	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AWM72_05815	ENOG4105CHW	UPF0052 protein
AWM72_05820	ENOG4105CIE	May be required for sporulation (By similarity)
AWM72_05830	ENOG4105DI5	UPF0365 protein
AWM72_05840	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
AWM72_05850	ENOG4108UUM	single-stranded DNA-binding protein
AWM72_05855	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AWM72_05860	ENOG4105BZU	Histidine kinase
AWM72_05865	ENOG4105DR4	Methyltransferase
AWM72_05870	ENOG4105CBX	hi0933 family
AWM72_05885	ENOG4105CP9	extracellular ligand-binding receptor
AWM72_05890	ENOG4105C32	Amino acid ABC transporter (Permease)
AWM72_05895	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
AWM72_05900	ENOG4105C0Z	ABC transporter
AWM72_05905	ENOG4108IV0	ABC, transporter
AWM72_05910	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
AWM72_05925	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AWM72_05935	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AWM72_05940	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AWM72_05945	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AWM72_05950	ENOG4108K88	Membrane
AWM72_05960	ENOG4105CGK	Exodeoxyribonuclease III
AWM72_05970	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AWM72_05975	ENOG4105BZU	Histidine kinase
AWM72_05995	ENOG4105Q2H	domain protein
AWM72_06000	ENOG4105C0H	protease
AWM72_06015	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AWM72_06025	ENOG4108ZJ4	polysaccharide deacetylase
AWM72_06030	ENOG4108ZB6	transcriptional regulator AsnC family
AWM72_06035	ENOG4105CHM	Aminotransferase
AWM72_06055	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AWM72_06070	ENOG4105CJ1	ABC, transporter
AWM72_06105	ENOG4105CJ1	ABC, transporter
AWM72_06120	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AWM72_06130	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AWM72_06160	ENOG4105D2N	Aldolase
AWM72_06165	ENOG4105RM9	Protocatechuate 3,4-dioxygenase alpha
AWM72_06175	ENOG4105D1Q	UPF0246 protein
AWM72_06190	ENOG4105CE1	Ferrous iron transport protein b
AWM72_06210	ENOG4108V06	Glutathione peroxidase
AWM72_06215	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
AWM72_06235	ENOG4107QPK	)-transporter
AWM72_06240	ENOG4105CSR	polyphosphate kinase 2
AWM72_06245	ENOG4108IJ7	Glycine betaine
AWM72_06265	ENOG4108IPW	abc transporter atp-binding protein
AWM72_06285	ENOG4105WWK	YheO domain protein
AWM72_06300	ENOG4108JPW	Aminotransferase
AWM72_06315	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AWM72_06330	ENOG4105K3M	)-transporter
AWM72_06345	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
AWM72_06410	ENOG4105DZC	cytosine deaminase
AWM72_06415	ENOG4105F27	Major Facilitator
AWM72_06420	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AWM72_06435	ENOG4105RKW	reductase (By
AWM72_06450	ENOG4105EEI	dihydropteroate synthase
AWM72_06460	ENOG4108Q52	Methyltransferase cognate corrinoid protein
AWM72_06470	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AWM72_06480	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AWM72_06485	ENOG4105CGZ	zinc metallopeptidase
AWM72_06495	ENOG4105EJQ	L-serine dehydratase
AWM72_06500	ENOG4105CFC	Transporter
AWM72_06505	ENOG4108J5H	Homocysteine s-methyltransferase
AWM72_06515	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AWM72_06520	ENOG4105CHF	Glutathione S-transferase
AWM72_06525	ENOG4105DRP	amino acid AbC transporter
AWM72_06530	ENOG4105EAD	ABC transporter
AWM72_06535	ENOG4105CT1	(ABC) transporter
AWM72_06540	ENOG4105CDA	abc transporter atp-binding protein
AWM72_06560	ENOG410902V	Modulates RecA activity (By similarity)
AWM72_06565	ENOG4105CEN	a g-specific adenine glycosylase
AWM72_06570	ENOG4105EVI	UPF0374 protein
AWM72_06580	ENOG4108IUM	Glycogen debranching enzyme
AWM72_06590	ENOG4105G5W	regulator Fur family
AWM72_06595	ENOG4105II7	pyrroline-5-carboxylate reductase
AWM72_06690	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AWM72_06705	ENOG4105C5I	Dehydrogenase
AWM72_06710	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
AWM72_06715	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AWM72_06720	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AWM72_06725	ENOG4105BZ4	penicillin-binding protein
AWM72_06735	ENOG4107VRP	DNA repair exonuclease
AWM72_06740	ENOG4106D4I	domain protein
AWM72_06745	ENOG4105EQI	Metal Dependent Phosphohydrolase
AWM72_06760	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
AWM72_06770	ENOG4105K59	histidine triad (HIT) protein
AWM72_06785	ENOG4108V15	phosphotransferase enzyme family
AWM72_06800	ENOG4108VDD	TRNA binding domain protein
AWM72_06810	ENOG4105DFU	Cell wall formation (By similarity)
AWM72_06840	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AWM72_06845	ENOG4105EUJ	GTP cyclohydrolase i
AWM72_06850	ENOG4105KRF	dihydroneopterin aldolase
AWM72_06855	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AWM72_06870	ENOG4105C2M	dna polymerase I
AWM72_06875	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AWM72_06880	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AWM72_06885	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AWM72_06905	ENOG4105VBF	alkaline shock protein
AWM72_06910	ENOG4105C22	threonyL-tRNA synthetase
AWM72_06930	ENOG4105D01	(LipO)protein
AWM72_06935	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AWM72_06940	ENOG4105VJV	50s ribosomal protein L35
AWM72_06945	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AWM72_06960	ENOG4105HTX	biosynthesis protein
AWM72_06965	ENOG4108QV3	biosynthesis protein
AWM72_06975	ENOG4105D3Q	Sugar transferase
AWM72_06990	ENOG4105C5E	polysaccharide biosynthesis protein
AWM72_07000	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
AWM72_07020	ENOG4105K64	Glycosyl transferase, family 2
AWM72_07030	ENOG4105PSV	Polysaccharide Biosynthesis Protein
AWM72_07105	ENOG4105C5Y	PTS System
AWM72_07110	ENOG4105C2F	Histidine kinase
AWM72_07115	ENOG4107VQW	regulatoR
AWM72_07130	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AWM72_07135	ENOG4108R6K	riboflavin synthase, subunit alpha
AWM72_07140	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AWM72_07145	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AWM72_07150	ENOG4107EFR	Flavocytochrome c
AWM72_07155	ENOG4105D6U	Sodium Glutamate Symporter
AWM72_07165	ENOG4105EGS	Mechanosensitive ion channel
AWM72_07180	ENOG4105DTD	Dehydrogenase
AWM72_07200	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
AWM72_07205	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AWM72_07210	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AWM72_07215	ENOG4105PUK	Membrane
AWM72_07225	ENOG4108UW5	maltose o-acetyltransferase
AWM72_07235	ENOG4105VG1	fes assembly suf system protein
AWM72_07260	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AWM72_07265	ENOG4108UMI	ABC transporter, permease
AWM72_07270	ENOG4105D01	(LipO)protein
AWM72_07280	ENOG4105DF9	Lipoate-protein, ligase
AWM72_07285	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
AWM72_07290	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
AWM72_07295	ENOG4105C31	Tryptophanyl-tRNA synthetase
AWM72_07310	ENOG4105T58	Dithiol-disulfide isomerase
AWM72_07315	ENOG4105MIX	Adenylate cyclase
AWM72_07325	ENOG4105EMS	pseudouridine synthase
AWM72_07330	ENOG4105CJW	magnesium transporter
AWM72_07335	ENOG4105CVG	Homoserine O-transsuccinylase
AWM72_07340	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AWM72_07350	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AWM72_07360	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AWM72_07365	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AWM72_07370	ENOG4105KRI	phosphocarrier protein (HPr
AWM72_07375	ENOG4107IN1	Protein of unknown function (DUF1797)
AWM72_07380	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AWM72_07385	ENOG4105D6E	homoserine dehydrogenase
AWM72_07390	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AWM72_07395	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
AWM72_07400	ENOG4105CE4	GlcNAc 6-P deacetylase
AWM72_07410	ENOG4105E98	transcriptional regulator DeoR family
AWM72_07415	ENOG4105DE4	1-phosphofructokinase
AWM72_07420	ENOG4105DM4	PTS System
AWM72_07425	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AWM72_07430	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AWM72_07435	ENOG4105VIE	preprotein translocase, subunit YajC
AWM72_07450	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AWM72_07460	ENOG4105SFS	phosphoesterase RecJ domain protein
AWM72_07475	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AWM72_07490	ENOG4107RF6	penicillin-binding protein
AWM72_07495	ENOG4105WDJ	50S ribosomal protein L33
AWM72_07500	ENOG4107ZXI	Rhomboid family
AWM72_07505	ENOG4105DKQ	ROK family
AWM72_07510	ENOG4105WZW	rhodanese family
AWM72_07515	ENOG4108VX5	3-methyladenine DNA glycosylase
AWM72_07520	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AWM72_07525	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AWM72_07530	ENOG4105VEQ	Cold shock protein
AWM72_07535	ENOG4105W5Q	DNA repair protein (RadC
AWM72_07550	ENOG4107X35	defense response to bacterium
AWM72_07555	ENOG4105C8T	Leucyl-tRNA synthetase
AWM72_07575	ENOG4107QSE	Dipeptidase
AWM72_07580	ENOG4108RWN	rrna methyltransferase
AWM72_07595	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AWM72_07600	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AWM72_07605	ENOG4108IJ2	phosphate acetyltransferase
AWM72_07610	ENOG4105K8N	protein family UPF0079, ATPase
AWM72_07630	ENOG4108JJB	ABC transporter
AWM72_07645	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
AWM72_07680	ENOG4105C6T	cysteine synthase
AWM72_07685	ENOG4105D7W	serine acetyltransferase
AWM72_07695	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AWM72_07710	ENOG4108R96	Methyltransferase, YaeB family
AWM72_07735	ENOG4105E5Q	amino acid AbC transporter
AWM72_07750	ENOG4105C98	muts2 protein
AWM72_07755	ENOG4105K63	Thioredoxin
AWM72_07760	ENOG4108Z5K	methylglyoxal synthase
AWM72_07765	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AWM72_07770	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AWM72_07775	ENOG4105D8X	mechanosensitive ion channel
AWM72_07790	ENOG4105ETE	Transcriptional regulator (LacI family
AWM72_07795	ENOG4105BZ4	penicillin-binding protein
AWM72_07805	ENOG4105CDY	transcriptional regulatory protein
AWM72_07810	ENOG4105BZ1	(ABC) transporter
AWM72_07815	ENOG4105BZ1	(ABC) transporter
AWM72_07820	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AWM72_07830	ENOG4105F1A	Pyruvate formate-lyase
AWM72_07840	ENOG4106C6A	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AWM72_07845	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
AWM72_07850	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
AWM72_07925	ENOG4105DC7	peptidase M24
AWM72_07930	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AWM72_07940	ENOG4105M7K	Involved in the transcription termination process (By similarity)
AWM72_07945	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AWM72_07950	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AWM72_07955	ENOG41084DP	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AWM72_07965	ENOG4105DX0	Hemolysin A
AWM72_07970	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AWM72_07975	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AWM72_07980	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AWM72_07990	ENOG4105D01	(LipO)protein
AWM72_07995	ENOG41080Y5	BioY family
AWM72_08010	ENOG4105EGD	dinuclear metal center protein, YbgI family
AWM72_08015	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
AWM72_08020	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AWM72_08025	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
AWM72_08040	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AWM72_08045	ENOG4105C34	Pseudouridine synthase
AWM72_08050	ENOG4105VXM	UPF0154 protein
AWM72_08065	ENOG4105CE9	30S ribosomal protein S2
AWM72_08070	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AWM72_08075	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AWM72_08080	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AWM72_08085	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AWM72_08090	ENOG4105KNE	Phosphatidate cytidylyltransferase
AWM72_08095	ENOG4105DZP	Membrane-associated zinc metalloprotease
AWM72_08100	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
AWM72_08120	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AWM72_08125	ENOG4105CHV	Transcription elongation factor NusA
AWM72_08130	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
AWM72_08145	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AWM72_08150	ENOG4105DEN	Luciferase family
AWM72_08155	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AWM72_08160	ENOG4105DTN	riboflavin biosynthesis protein ribF
AWM72_08165	ENOG4105CSA	Coproporphyrinogen iii oxidase
AWM72_08175	ENOG4105DY9	regulatoR
AWM72_08180	ENOG4108HRK	Histidine kinase
AWM72_08185	ENOG4105D01	(LipO)protein
AWM72_08190	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AWM72_08195	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AWM72_08200	ENOG4105CFG	Acts as a chaperone (By similarity)
AWM72_08205	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AWM72_08210	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
AWM72_08215	ENOG4105D7T	ABC transporter
AWM72_08230	ENOG4105C5X	domain protein
AWM72_08235	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AWM72_08255	ENOG4105C1A	potassium transporter peripheral membrane
AWM72_08260	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AWM72_08265	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
AWM72_08345	ENOG4105C7J	ABC transporter, permease
AWM72_08350	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AWM72_08360	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AWM72_08365	ENOG4105D49	3-dehydroquinate synthase
AWM72_08370	ENOG4105E2X	shikimate dehydrogenase
AWM72_08375	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
AWM72_08380	ENOG4105D49	3-dehydroquinate synthase
AWM72_08385	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AWM72_08390	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AWM72_08395	ENOG4105CQC	Prephenate dehydratase
AWM72_08400	ENOG4105D01	(LipO)protein
AWM72_08415	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
AWM72_08425	ENOG4105CD3	dihydroorotase
AWM72_08430	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AWM72_08435	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AWM72_08440	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
AWM72_08445	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
AWM72_08465	ENOG4105WYW	fructose-bisphosphate aldolase
AWM72_08470	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AWM72_08475	ENOG4105C1A	potassium transporter peripheral membrane
AWM72_08480	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
AWM72_08495	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AWM72_08500	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
AWM72_08505	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
AWM72_08510	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AWM72_08515	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AWM72_08520	ENOG4105C79	DNA protecting protein DprA
AWM72_08525	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AWM72_08530	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
AWM72_08545	ENOG4106E6V	UPF0346 protein
AWM72_08555	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
AWM72_08560	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AWM72_08565	ENOG4105C5H	ABC transporter
AWM72_08570	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AWM72_08575	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AWM72_08580	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
AWM72_08585	ENOG4107YCR	Transcriptional regulator, ARSR family
AWM72_08605	ENOG4105DEN	Luciferase family
AWM72_08610	ENOG4105CSM	endonuclease III
AWM72_08615	ENOG4108UK2	deaminase
AWM72_08625	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AWM72_08635	ENOG4108Z66	YbaK ebsC protein
AWM72_08640	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AWM72_08645	ENOG41067VN	Glutaredoxin
AWM72_08650	ENOG4108JJB	ABC transporter
AWM72_08665	ENOG4105F23	Fibronectin-binding protein
AWM72_08670	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AWM72_08675	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AWM72_08680	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AWM72_08700	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
AWM72_08705	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
AWM72_08710	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AWM72_08720	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AWM72_08725	ENOG4105C9A	Phoh family
AWM72_08730	ENOG4105KTH	gatB Yqey
AWM72_08735	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
AWM72_08740	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
AWM72_08750	ENOG4105N80	Ferric uptake regulator, Fur family
AWM72_08755	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AWM72_08765	ENOG4105D07	Signal peptide peptidase, SppA
AWM72_08770	ENOG4105C9M	aspartyl-trna synthetase
AWM72_08775	ENOG4105CUT	histidyl-tRNA synthetase
AWM72_08790	ENOG4105I08	Pseudouridine synthase
AWM72_08795	ENOG4105CKU	formyltetrahydrofolate synthetase
AWM72_08820	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AWM72_08830	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AWM72_08835	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AWM72_08840	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AWM72_08850	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
AWM72_08860	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AWM72_08885	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AWM72_08890	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AWM72_08900	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AWM72_08905	ENOG4105CHR	reductase
AWM72_08915	ENOG4105EA8	2-Nitropropane dioxygenase
AWM72_08920	ENOG410854A	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AWM72_08935	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AWM72_08940	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
AWM72_08945	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AWM72_08950	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AWM72_08965	ENOG4105C8Y	Acetylornithine aminotransferase
AWM72_08970	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
AWM72_08980	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AWM72_08985	ENOG4105DBV	ornithine carbamoyltransferase
AWM72_09000	ENOG4105BZA	Phosphoglycerate kinase
AWM72_09005	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AWM72_09035	ENOG4107VQW	regulatoR
AWM72_09040	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AWM72_09070	ENOG4108S4A	n-acetylmuramoyl-l-alanine amidase
AWM72_09135	ENOG4105CAR	Terminase, large subunit