locus-tag	class	description
AWM73_00095	ENOG4105C28	cystathionine
AWM73_00100	ENOG4105EGI	Transcriptional regulator
AWM73_00115	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AWM73_00120	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AWM73_00145	ENOG4105RNB	
AWM73_00150	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AWM73_00160	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
AWM73_00165	ENOG4105DWF	phosphomethylpyrimidine kinase
AWM73_00170	ENOG4108EKI	Dehydrogenase
AWM73_00190	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AWM73_00195	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AWM73_00200	ENOG4105CTP	PilT protein domain protein
AWM73_00205	ENOG4108HCJ	Hydrolase
AWM73_00210	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AWM73_00220	ENOG4105CP9	extracellular ligand-binding receptor
AWM73_00235	ENOG4105C32	Amino acid ABC transporter (Permease)
AWM73_00240	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
AWM73_00245	ENOG4105C0Z	ABC transporter
AWM73_00250	ENOG4108IV0	ABC, transporter
AWM73_00255	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AWM73_00265	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AWM73_00270	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
AWM73_00280	ENOG4105C4R	Atp-dependent dna helicase
AWM73_00285	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AWM73_00295	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AWM73_00300	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AWM73_00305	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AWM73_00325	ENOG4105D5T	phosphonate abc transporter
AWM73_00340	ENOG4105CGH	5'-nucleotidase
AWM73_00350	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
AWM73_00355	ENOG4105CV8	reductase
AWM73_00360	ENOG4108MXZ	Esterase
AWM73_00365	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AWM73_00390	ENOG4108JJB	ABC transporter
AWM73_00395	ENOG4105BZ1	(ABC) transporter
AWM73_00400	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
AWM73_00460	ENOG4105CZV	ABC transporter
AWM73_00475	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AWM73_00490	ENOG4105CJ1	ABC, transporter
AWM73_00520	ENOG4105CB5	ATP-dependent DNA helicase recG
AWM73_00525	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AWM73_00530	ENOG4105BZU	Histidine kinase
AWM73_00535	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AWM73_00545	ENOG41067QW	Transcriptional regulator
AWM73_00580	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AWM73_00585	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AWM73_00615	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AWM73_00620	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AWM73_00630	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AWM73_00640	ENOG4105CJZ	response regulator
AWM73_00695	ENOG4105C72	UPF0176 protein
AWM73_00700	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AWM73_00705	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
AWM73_00720	ENOG4105KWG	Pfam:DUF1696
AWM73_00730	ENOG4108UQV	Membrane
AWM73_00735	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
AWM73_00745	ENOG4105CMR	udp-glucose 4-epimerase
AWM73_00750	ENOG4105BZF	Glycosyl transferase (Group 1
AWM73_00795	ENOG4105CHF	Glutathione S-transferase
AWM73_00805	ENOG4105C5I	Dehydrogenase
AWM73_00815	ENOG4105CGK	Exodeoxyribonuclease III
AWM73_00835	ENOG41060M0	Crispr-associated protein, cse4 family
AWM73_00840	ENOG4108VWQ	crispr-associated protein
AWM73_00850	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
AWM73_00855	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
AWM73_00860	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
AWM73_00870	ENOG4105VPS	UPF0291 protein
AWM73_00875	ENOG41072GX	Peptidase M22 Glycoprotease
AWM73_00885	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
AWM73_00890	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AWM73_00900	ENOG4105C5H	ABC transporter
AWM73_00905	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
AWM73_00915	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AWM73_00920	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AWM73_00925	ENOG4105C83	adenylosuccinate lyase
AWM73_00935	ENOG4105DYB	Isoaspartyl dipeptidase
AWM73_00940	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
AWM73_00945	ENOG4105C26	Dehydrogenase
AWM73_00950	ENOG4105E5Q	amino acid AbC transporter
AWM73_00955	ENOG4105CH7	arginosuccinase
AWM73_00960	ENOG4105E5Q	amino acid AbC transporter
AWM73_00970	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
AWM73_00975	ENOG4105CTS	PTS system mannitol-specific
AWM73_00980	ENOG4105ETD	TRANSCRIPTIONal
AWM73_00990	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
AWM73_01005	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AWM73_01010	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
AWM73_01020	ENOG4105ZMH	deoxynucleoside kinase
AWM73_01025	ENOG4108UHU	Aldolase
AWM73_01030	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AWM73_01040	ENOG41081UC	Inherit from COG: Competence protein
AWM73_01050	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AWM73_01055	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AWM73_01060	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AWM73_01065	ENOG4105BZU	Histidine kinase
AWM73_01070	ENOG4107S17	Phosphate-binding protein
AWM73_01075	ENOG4105C8U	phosphate abc transporter
AWM73_01080	ENOG4105E2Z	phosphate ABC transporter (Permease
AWM73_01085	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AWM73_01100	ENOG4107ZYR	domain protein
AWM73_01105	ENOG4105DPH	UPF0371 protein
AWM73_01110	ENOG4105CNT	hydrolase family 2
AWM73_01115	ENOG4105DSE	periplasmic solute binding protein
AWM73_01125	ENOG4105DF9	Lipoate-protein, ligase
AWM73_01155	ENOG4105CHF	Glutathione S-transferase
AWM73_01170	ENOG4105C8M	UPF0272 protein
AWM73_01175	ENOG4105C8M	UPF0272 protein
AWM73_01180	ENOG4105DVM	PP-loop domain protein
AWM73_01185	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
AWM73_01195	ENOG41075H3	AraC family transcriptional regulator
AWM73_01200	ENOG4105DBV	ornithine carbamoyltransferase
AWM73_01210	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AWM73_01225	ENOG4105C5B	carbamate kinase
AWM73_01230	ENOG4105SYT	Methylenetetrahydrofolate reductase
AWM73_01245	ENOG4108YZT	Adenosylcobinamide kinase
AWM73_01250	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
AWM73_01255	ENOG4105GCF	PGAM
AWM73_01260	ENOG4107QZB	decarboxylase
AWM73_01265	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
AWM73_01285	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AWM73_01290	ENOG41081F0	Precorrin-8x methylmutase
AWM73_01300	ENOG4108DR9	Cobalt-precorrin-6Y C(5)-methyltransferase
AWM73_01305	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
AWM73_01310	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
AWM73_01315	ENOG4108P62	biosynthesis protein (CbiG)
AWM73_01320	ENOG4105E4R	Precorrin-3B C17-methyltransferase
AWM73_01325	ENOG4108JTQ	reductase
AWM73_01335	ENOG4107PPM	cobalt chelatase
AWM73_01340	ENOG4105DVK	Precorrin-2 c20-methyltransferase
AWM73_01345	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AWM73_01355	ENOG4108Z73	Siroheme synthase
AWM73_01360	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AWM73_01370	ENOG4107UWA	esterase
AWM73_01375	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AWM73_01380	ENOG4105DU0	nucleoside hydrolase
AWM73_01400	ENOG410667J	hydrolase
AWM73_01405	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AWM73_01415	ENOG4105VKD	bioY protein
AWM73_01430	ENOG4105CMQ	Chloride channel
AWM73_01435	ENOG41068JE	domain protein
AWM73_01440	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AWM73_01445	ENOG4105BZU	Histidine kinase
AWM73_01465	ENOG4105Q2H	domain protein
AWM73_01470	ENOG4105C0H	protease
AWM73_01475	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AWM73_01485	ENOG4108ZB6	transcriptional regulator AsnC family
AWM73_01490	ENOG4105CHM	Aminotransferase
AWM73_01515	ENOG4105C5F	glutamine synthetase
AWM73_01525	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
AWM73_01535	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AWM73_01540	ENOG4105F8V	Hydrolase, tatD family
AWM73_01550	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AWM73_01555	ENOG4108IUW	ABC transporter
AWM73_01570	ENOG4105W42	Veg protein
AWM73_01575	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AWM73_01580	ENOG4105DSE	periplasmic solute binding protein
AWM73_01585	ENOG4105FDK	ABC transporter
AWM73_01595	ENOG4105DFT	pur operon repressor
AWM73_01615	ENOG4107T94	Endo-14-beta-xylanase
AWM73_01630	ENOG4105D2T	synthase
AWM73_01640	ENOG4105K64	Glycosyl transferase, family 2
AWM73_01645	ENOG4108RYC	glycosyltransferase
AWM73_01650	ENOG4105K64	Glycosyl transferase, family 2
AWM73_01660	ENOG4107SJB	teichoic acid biosynthesis
AWM73_01670	ENOG4107QSI	ABC, transporter
AWM73_01680	ENOG4105NQC	Flavodoxin
AWM73_01695	ENOG4108KGH	TRANSCRIPTIONal
AWM73_01705	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
AWM73_01715	ENOG4105EPR	degv family
AWM73_01720	ENOG4108Z4K	mutator MutT protein
AWM73_01730	ENOG4105HTX	biosynthesis protein
AWM73_01735	ENOG4108QV3	biosynthesis protein
AWM73_01745	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AWM73_01750	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AWM73_01780	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AWM73_01785	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AWM73_01790	ENOG4105KJF	protein tyrosine phosphatase
AWM73_01795	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AWM73_01805	ENOG4105DC7	peptidase M24
AWM73_01810	ENOG4107QSE	Dipeptidase
AWM73_01815	ENOG4108J59	Extracellular solute-binding protein, family 5
AWM73_01835	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AWM73_01840	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AWM73_01850	ENOG4108JQ7	(ABC) transporter
AWM73_01855	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
AWM73_01875	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
AWM73_01895	ENOG4105K63	Thioredoxin
AWM73_01900	ENOG4108MR7	Arylsulfotransferase
AWM73_01905	ENOG4105HMI	Membrane
AWM73_01910	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AWM73_01915	ENOG4107QID	Threonine synthase
AWM73_01920	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AWM73_01925	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AWM73_01960	ENOG4105CT1	(ABC) transporter
AWM73_01965	ENOG4105EAD	ABC transporter
AWM73_01970	ENOG4105DRP	amino acid AbC transporter
AWM73_01980	ENOG4105WBI	UPF0223 protein
AWM73_01985	ENOG4105ECY	inositol monophosphatase
AWM73_01990	ENOG4105CI3	gtp-binding protein typa
AWM73_01995	ENOG4105CNI	cell division protein FtsW
AWM73_02000	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
AWM73_02005	ENOG4105WUC	UPF0298 protein
AWM73_02015	ENOG4105EKQ	RNA-directed DNA polymerase
AWM73_02025	ENOG4106H78	methyltransferase
AWM73_02030	ENOG4105KQC	Competence protein
AWM73_02035	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
AWM73_02045	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AWM73_02055	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AWM73_02060	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AWM73_02065	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AWM73_02070	ENOG4105EKQ	RNA-directed DNA polymerase
AWM73_02075	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AWM73_02090	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AWM73_02100	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AWM73_02105	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AWM73_02110	ENOG4105C25	Primosomal protein n'
AWM73_02115	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AWM73_02120	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AWM73_02130	ENOG4105D9P	serine threonine protein kinase
AWM73_02135	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AWM73_02140	ENOG4105DJV	ribulose-phosphate 3-epimerase
AWM73_02150	ENOG4105VB9	50S ribosomal protein l28
AWM73_02155	ENOG4108ZAA	Alkaline-shock protein
AWM73_02160	ENOG4105DP4	dak2 domain fusion protein ylov
AWM73_02165	ENOG4105DEN	Luciferase family
AWM73_02170	ENOG4105CB5	ATP-dependent DNA helicase recG
AWM73_02175	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
AWM73_02180	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AWM73_02185	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AWM73_02190	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AWM73_02195	ENOG410667J	hydrolase
AWM73_02200	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AWM73_02205	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
AWM73_02225	ENOG4105BZ1	(ABC) transporter
AWM73_02235	ENOG4105DI5	UPF0365 protein
AWM73_02245	ENOG4105K5M	30s ribosomal protein S16
AWM73_02250	ENOG4105VB6	UPF0109 protein
AWM73_02255	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AWM73_02260	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AWM73_02265	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AWM73_02285	ENOG4105DND	Transcriptional regulator
AWM73_02290	ENOG4107GJV	short-chain dehydrogenase reductase
AWM73_02295	ENOG4107SG5	Dehydrogenase
AWM73_02300	ENOG4107RE7	phosphate butyryltransferase
AWM73_02305	ENOG4105CKM	Branched-chain carboxylic acid kinase
AWM73_02310	ENOG4105E39	Enoyl-CoA hydratase
AWM73_02320	ENOG4107RSM	transcriptional regulator
AWM73_02325	ENOG4105EA8	2-Nitropropane dioxygenase
AWM73_02335	ENOG4107QN2	dihydrolipoyl dehydrogenase
AWM73_02340	ENOG4107RUY	(E1 component), alpha subunit
AWM73_02350	ENOG4107QKR	Dehydrogenase
AWM73_02360	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AWM73_02365	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AWM73_02390	ENOG4105SFS	phosphoesterase RecJ domain protein
AWM73_02395	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
AWM73_02400	ENOG4105C1J	atp-dependent rna helicase
AWM73_02410	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AWM73_02420	ENOG4107RF6	penicillin-binding protein
AWM73_02440	ENOG4105CHR	reductase
AWM73_02445	ENOG4107ZXI	Rhomboid family
AWM73_02455	ENOG4105WZW	rhodanese family
AWM73_02460	ENOG4108VX5	3-methyladenine DNA glycosylase
AWM73_02465	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AWM73_02470	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AWM73_02475	ENOG4105W5Q	DNA repair protein (RadC
AWM73_02500	ENOG4105C2M	dna polymerase I
AWM73_02505	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AWM73_02515	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AWM73_02530	ENOG4105C22	threonyL-tRNA synthetase
AWM73_02540	ENOG4108UVJ	appr-1-p processing domain protein
AWM73_02545	ENOG4105CH2	amidohydrolase
AWM73_02550	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AWM73_02555	ENOG4105VJV	50s ribosomal protein L35
AWM73_02560	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AWM73_02565	ENOG4105HUF	DNA protection during starvation protein
AWM73_02570	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AWM73_02575	ENOG4108UMI	ABC transporter, permease
AWM73_02580	ENOG4105D01	(LipO)protein
AWM73_02595	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
AWM73_02600	ENOG4105C31	Tryptophanyl-tRNA synthetase
AWM73_02625	ENOG4105EMS	pseudouridine synthase
AWM73_02630	ENOG4105CJW	magnesium transporter
AWM73_02635	ENOG4105CVG	Homoserine O-transsuccinylase
AWM73_02640	ENOG41082BV	acetyltransferase
AWM73_02685	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AWM73_02690	ENOG4105E5Q	amino acid AbC transporter
AWM73_02700	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AWM73_02705	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AWM73_02710	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AWM73_02715	ENOG4105KRI	phosphocarrier protein (HPr
AWM73_02720	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AWM73_02725	ENOG4105BZF	Glycosyl transferase (Group 1
AWM73_02735	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AWM73_02740	ENOG4105D6E	homoserine dehydrogenase
AWM73_02745	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AWM73_02750	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
AWM73_02755	ENOG4105CQW	ribosome biogenesis GTPase YqeH
AWM73_02760	ENOG410812S	Rna-binding protein
AWM73_02765	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AWM73_02770	ENOG4108WF2	Metal Dependent Phosphohydrolase
AWM73_02775	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
AWM73_02780	ENOG4105DXX	methyltransferase
AWM73_02785	ENOG4105CDE	UPF0348 protein
AWM73_02795	ENOG41067VY	50S ribosomal protein L32
AWM73_02820	ENOG4105CJN	penicillin-binding protein
AWM73_02825	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AWM73_02835	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AWM73_02840	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
AWM73_02845	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AWM73_02855	ENOG4105DFA	alanine racemase domain protein
AWM73_02860	ENOG41067XK	integral membrane protein
AWM73_02865	ENOG4105DBK	s4 domain protein
AWM73_02875	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AWM73_02880	ENOG4105VEQ	Cold shock protein
AWM73_02885	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AWM73_02895	ENOG4108YZ4	nudix hydrolase
AWM73_02905	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
AWM73_02910	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AWM73_02915	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
AWM73_02920	ENOG4105C3J	Cysteine desulfurase
AWM73_02935	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
AWM73_02940	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AWM73_02945	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
AWM73_02950	ENOG410855V	Acylphosphatase
AWM73_02955	ENOG4105CNU	cell division protein FtsK
AWM73_02960	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AWM73_02965	ENOG4105CEV	competence damage-inducible protein
AWM73_02970	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AWM73_02975	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
AWM73_02980	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
AWM73_03115	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AWM73_03120	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AWM73_03125	ENOG4105E0X	reductase
AWM73_03130	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AWM73_03135	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AWM73_03140	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AWM73_03145	ENOG4105C0B	DNA polymerase III (alpha subunit)
AWM73_03150	ENOG4105CTQ	phosphohexokinase
AWM73_03155	ENOG4105CA9	Pyruvate kinase
AWM73_03160	ENOG4105QNR	S1 RNA binding domain protein
AWM73_03170	ENOG4105EKQ	RNA-directed DNA polymerase
AWM73_03190	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
AWM73_03195	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AWM73_03200	ENOG4105FE9	pseudouridine synthase
AWM73_03205	ENOG4108SAX	Membrane
AWM73_03215	ENOG4105E5H	Transposase
AWM73_03230	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AWM73_03240	ENOG4105CAT	Cytidine monophosphate kinase
AWM73_03245	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AWM73_03250	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AWM73_03255	ENOG4105K70	DNA-binding protein
AWM73_03265	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AWM73_03270	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AWM73_03305	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AWM73_03315	ENOG4107QYV	phosphohexose isomerase
AWM73_03460	ENOG4105E98	transcriptional regulator DeoR family
AWM73_03465	ENOG4105DE4	1-phosphofructokinase
AWM73_03470	ENOG4105DM4	PTS System
AWM73_03475	ENOG4105D01	(LipO)protein
AWM73_03495	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AWM73_03510	ENOG4105BZA	Phosphoglycerate kinase
AWM73_03515	ENOG4105CP7	Triose-phosphate isomerase
AWM73_03520	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AWM73_03525	ENOG4105MMD	transcriptional regulator
AWM73_03540	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AWM73_03560	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AWM73_03565	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AWM73_03570	ENOG4106HBX	Transcriptional Regulator AraC Family
AWM73_03595	ENOG4107RIV	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AWM73_03600	ENOG4107RGD	Major Facilitator superfamily
AWM73_03605	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AWM73_03610	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AWM73_03615	ENOG4105DGA	Diaminopimelate dehydrogenase
AWM73_03620	ENOG4105DCF	alanine dehydrogenase
AWM73_03625	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AWM73_03630	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
AWM73_03640	ENOG4105DMS	mur ligase
AWM73_03645	ENOG4105F1K	Glutamine amidotransferase
AWM73_03655	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AWM73_03660	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AWM73_03665	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AWM73_03670	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AWM73_03675	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AWM73_03680	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AWM73_03690	ENOG4105CN5	Metallo-Beta-Lactamase
AWM73_03695	ENOG4106EHS	UPF0356 protein
AWM73_03700	ENOG4108UT2	hemolysin iii
AWM73_03720	ENOG4105W8X	HesB YadR YfhF-family protein
AWM73_03730	ENOG4105CS9	pantothenic acid kinase
AWM73_03735	ENOG4105C02	permease
AWM73_03740	ENOG4105BZ1	(ABC) transporter
AWM73_03745	ENOG4105BZ1	(ABC) transporter
AWM73_03765	ENOG4105E5Q	amino acid AbC transporter
AWM73_03775	ENOG4105C5H	ABC transporter
AWM73_03785	ENOG4105KJF	protein tyrosine phosphatase
AWM73_03790	ENOG4108K4B	hydrolase
AWM73_03795	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AWM73_03820	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
AWM73_03825	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AWM73_03830	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AWM73_03835	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AWM73_03840	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AWM73_03845	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AWM73_03850	ENOG4105CFH	Aspartokinase
AWM73_03860	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AWM73_03870	ENOG4105E5Q	amino acid AbC transporter
AWM73_03875	ENOG4105CDA	abc transporter atp-binding protein
AWM73_03880	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AWM73_03890	ENOG4105CXT	aspartate transcarbamylase
AWM73_03895	ENOG4105CD3	dihydroorotase
AWM73_03900	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
AWM73_03915	ENOG4105K46	50S ribosomal protein l27
AWM73_03930	ENOG4105BZ1	(ABC) transporter
AWM73_03950	ENOG4105EPR	degv family
AWM73_03965	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AWM73_03970	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AWM73_03980	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
AWM73_04000	ENOG4105EGD	dinuclear metal center protein, YbgI family
AWM73_04005	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AWM73_04010	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
AWM73_04025	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AWM73_04030	ENOG4105C34	Pseudouridine synthase
AWM73_04035	ENOG4105VXM	UPF0154 protein
AWM73_04040	ENOG4105F6E	Acyl-transferase
AWM73_04060	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AWM73_04065	ENOG4108UMN	azlc family
AWM73_04070	ENOG4105KMT	branched-chain amino acid
AWM73_04075	ENOG4105C5R	Aminotransferase
AWM73_04080	ENOG4105E39	Enoyl-CoA hydratase
AWM73_04085	ENOG4107RSM	transcriptional regulator
AWM73_04090	ENOG4105CHR	reductase
AWM73_04095	ENOG4105CY2	Citrate transporter
AWM73_04100	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
AWM73_04105	ENOG4105CHU	acetyl-coa acetyltransferase
AWM73_04125	ENOG4105CE9	30S ribosomal protein S2
AWM73_04130	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AWM73_04135	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AWM73_04140	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AWM73_04145	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AWM73_04150	ENOG4105KNE	Phosphatidate cytidylyltransferase
AWM73_04155	ENOG4105DZP	Membrane-associated zinc metalloprotease
AWM73_04160	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
AWM73_04180	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AWM73_04185	ENOG4105CHV	Transcription elongation factor NusA
AWM73_04190	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
AWM73_04200	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AWM73_04205	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AWM73_04215	ENOG4105C7J	ABC transporter, permease
AWM73_04220	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AWM73_04230	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AWM73_04235	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AWM73_04240	ENOG4105DTN	riboflavin biosynthesis protein ribF
AWM73_04245	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AWM73_04255	ENOG4105CFG	Acts as a chaperone (By similarity)
AWM73_04260	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AWM73_04265	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AWM73_04275	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
AWM73_04285	ENOG4105CKU	formyltetrahydrofolate synthetase
AWM73_04290	ENOG4105C5H	ABC transporter
AWM73_04295	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AWM73_04300	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
AWM73_04310	ENOG4105VSD	UPF0346 protein
AWM73_04320	ENOG4105C3F	Signal peptidase i
AWM73_04325	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
AWM73_04330	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AWM73_04335	ENOG4105C79	DNA protecting protein DprA
AWM73_04340	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AWM73_04345	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AWM73_04350	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
AWM73_04360	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AWM73_04365	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AWM73_04370	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
AWM73_04380	ENOG4105C7J	ABC transporter, permease
AWM73_04385	ENOG4105E2Y	ABC, transporter
AWM73_04390	ENOG4108Q3X	Transcriptional regulator
AWM73_04400	ENOG4105CY2	Citrate transporter
AWM73_04410	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AWM73_04480	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AWM73_04500	ENOG4108HCJ	Hydrolase
AWM73_04505	ENOG4105FGM	Fructosamine kinase
AWM73_04510	ENOG4105WD1	Membrane
AWM73_04520	ENOG4105C5X	domain protein
AWM73_04540	ENOG4105FF5	Membrane
AWM73_04545	ENOG4105CBD	Diacylglycerol kinase
AWM73_04565	ENOG4105CSM	endonuclease III
AWM73_04570	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AWM73_04575	ENOG4108Z66	YbaK ebsC protein
AWM73_04580	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AWM73_04585	ENOG4107R37	Glutamate dehydrogenase
AWM73_04590	ENOG4108UK2	deaminase
AWM73_04600	ENOG4105F23	Fibronectin-binding protein
AWM73_04605	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AWM73_04610	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AWM73_04615	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AWM73_04620	ENOG4105EMU	Dehydrogenase
AWM73_04625	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AWM73_04640	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
AWM73_04645	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
AWM73_04650	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AWM73_04660	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AWM73_04665	ENOG4105C9A	Phoh family
AWM73_04670	ENOG4105KTH	gatB Yqey
AWM73_04675	ENOG4105VCC	30S ribosomal protein S21
AWM73_04690	ENOG4105UIB	(ABC) transporter
AWM73_04695	ENOG4108JQ9	ABC transporter
AWM73_04700	ENOG4105DIH	basic membrane
AWM73_04705	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
AWM73_04710	ENOG4105N80	Ferric uptake regulator, Fur family
AWM73_04715	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AWM73_04730	ENOG4105C9M	aspartyl-trna synthetase
AWM73_04735	ENOG4105CUT	histidyl-tRNA synthetase
AWM73_04745	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AWM73_04750	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AWM73_04765	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
AWM73_04775	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AWM73_04780	ENOG4105IW1	AmiS UreI transporter
AWM73_04785	ENOG4105ECY	inositol monophosphatase
AWM73_04795	ENOG4108K88	Membrane
AWM73_04800	ENOG4107EFR	Flavocytochrome c
AWM73_04815	ENOG4107EFR	Flavocytochrome c
AWM73_04820	ENOG4105VND	Ribonuclease
AWM73_04830	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AWM73_04835	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AWM73_04840	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AWM73_04845	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AWM73_04860	ENOG4105CHR	reductase
AWM73_04865	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AWM73_04870	ENOG4105EA8	2-Nitropropane dioxygenase
AWM73_04875	ENOG410854A	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AWM73_04880	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AWM73_04900	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AWM73_04910	ENOG4105VPH	UPF0473 protein
AWM73_04925	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AWM73_04935	ENOG4105C7H	Helicase, RecD TraA family
AWM73_04940	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AWM73_04950	ENOG4105C3J	Cysteine desulfurase
AWM73_04955	ENOG4105D1H	recombination factor protein RarA
AWM73_04970	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AWM73_04975	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AWM73_04995	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AWM73_05020	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AWM73_05025	ENOG4105CGZ	zinc metallopeptidase
AWM73_05040	ENOG4105C83	adenylosuccinate lyase
AWM73_05045	ENOG4105C12	Phosphoribosylglycinamide synthetase
AWM73_05050	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AWM73_05055	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AWM73_05060	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AWM73_05065	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AWM73_05070	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AWM73_05075	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
AWM73_05080	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
AWM73_05085	ENOG4105C8V	SAICAR synthetase
AWM73_05090	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AWM73_05095	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AWM73_05120	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AWM73_05135	ENOG4105DC8	reductase
AWM73_05165	ENOG4105C75	arginyL-tRNA synthetase
AWM73_05170	ENOG4107QRI	Phosphoketolase
AWM73_05175	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
AWM73_05190	ENOG4105C9K	Endothelin-converting enzyme 1
AWM73_05210	ENOG41080E8	Transcriptional regulator, Spx MgsR family
AWM73_05220	ENOG4107U9T	Pfam:Ribonuclease_BN
AWM73_05235	ENOG4108RVA	ribokinase
AWM73_05245	ENOG410667J	hydrolase
AWM73_05260	ENOG4105CD8	aminopeptidase N
AWM73_05270	ENOG41067QW	Transcriptional regulator
AWM73_05275	ENOG4105CSR	polyphosphate kinase 2
AWM73_05285	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
AWM73_05310	ENOG4105E5H	Transposase
AWM73_05355	ENOG4105PSV	Polysaccharide Biosynthesis Protein
AWM73_05380	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
AWM73_05390	ENOG4105C5E	polysaccharide biosynthesis protein
AWM73_05405	ENOG4105D3Q	Sugar transferase
AWM73_05415	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
AWM73_05420	ENOG4108QV3	biosynthesis protein
AWM73_05425	ENOG4105HTX	biosynthesis protein
AWM73_05430	ENOG4108KGH	TRANSCRIPTIONal
AWM73_05435	ENOG4107EFR	Flavocytochrome c
AWM73_05460	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AWM73_05465	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AWM73_05470	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AWM73_05475	ENOG4105DX0	Hemolysin A
AWM73_05485	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AWM73_05490	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AWM73_05495	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AWM73_05500	ENOG4105M7K	Involved in the transcription termination process (By similarity)
AWM73_05510	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AWM73_05515	ENOG4105DC7	peptidase M24
AWM73_05565	ENOG4107WUB	V-type ATPase 116 kDa subunit
AWM73_05585	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
AWM73_05590	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
AWM73_05595	ENOG4106C6A	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AWM73_05610	ENOG4105D8X	mechanosensitive ion channel
AWM73_05615	ENOG4105M59	Phosphodiesterase, mj0936 family
AWM73_05620	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AWM73_05630	ENOG4105D6U	Sodium Glutamate Symporter
AWM73_05635	ENOG4108Z5K	methylglyoxal synthase
AWM73_05645	ENOG4105K63	Thioredoxin
AWM73_05680	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AWM73_05700	ENOG4108R96	Methyltransferase, YaeB family
AWM73_05705	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
AWM73_05715	ENOG4105CN9	Peptidase m42 family protein
AWM73_05740	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AWM73_05745	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AWM73_05760	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
AWM73_05765	ENOG4105C6T	cysteine synthase
AWM73_05770	ENOG4105D7W	serine acetyltransferase
AWM73_05780	ENOG4108UZ3	Transporter
AWM73_05795	ENOG4108MGR	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane (By similarity)
AWM73_05805	ENOG41089G2	accessory Sec system protein Asp2
AWM73_05815	ENOG4105G62	Translocase subunit
AWM73_05820	ENOG4105GH9	galactofuranosyltransferase
AWM73_05825	ENOG4105EDE	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1 (By similarity)
AWM73_05830	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
AWM73_05845	ENOG4105D01	(LipO)protein
AWM73_05855	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AWM73_05860	ENOG4108YYH	Nadph-dependent fmn reductase
AWM73_05880	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
AWM73_05885	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
AWM73_05890	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AWM73_05915	ENOG4105DRS	transport system, permease
AWM73_05920	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
AWM73_05925	ENOG4108IJ9	(ABC) transporter
AWM73_05930	ENOG4105D9M	gamma-glutamylcysteine synthetase
AWM73_05940	ENOG4105C7K	acetolactate synthase
AWM73_05950	ENOG4108YYH	Nadph-dependent fmn reductase
AWM73_05955	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AWM73_05960	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AWM73_05980	ENOG4105CE4	GlcNAc 6-P deacetylase
AWM73_05990	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
AWM73_06025	ENOG4108WZW	RNA polymerase sigma
AWM73_06035	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
AWM73_06045	ENOG4105BZ1	(ABC) transporter
AWM73_06070	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AWM73_06075	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
AWM73_06080	ENOG4105CTZ	aminopeptidase c
AWM73_06090	ENOG4105BZ4	penicillin-binding protein
AWM73_06105	ENOG4105D7T	ABC transporter
AWM73_06125	ENOG4105CVJ	phosphoglycerate mutase
AWM73_06130	ENOG4108JJB	ABC transporter
AWM73_06150	ENOG4105K8N	protein family UPF0079, ATPase
AWM73_06155	ENOG4108UIC	UPF0340 protein
AWM73_06160	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AWM73_06180	ENOG4108IJ2	phosphate acetyltransferase
AWM73_06190	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AWM73_06195	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AWM73_06200	ENOG4105KVH	Transcriptional regulator
AWM73_06210	ENOG4108RWN	rrna methyltransferase
AWM73_06220	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
AWM73_06235	ENOG4105E5Q	amino acid AbC transporter
AWM73_06250	ENOG4105CDA	abc transporter atp-binding protein
AWM73_06260	ENOG4105C8T	Leucyl-tRNA synthetase
AWM73_06280	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AWM73_06285	ENOG4105DFU	Cell wall formation (By similarity)
AWM73_06295	ENOG4108VDD	TRNA binding domain protein
AWM73_06305	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AWM73_06325	ENOG4105K59	histidine triad (HIT) protein
AWM73_06335	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
AWM73_06340	ENOG4105X1N	Glycosyl transferase family 8
AWM73_06345	ENOG4105EQI	Metal Dependent Phosphohydrolase
AWM73_06350	ENOG4106D4I	domain protein
AWM73_06355	ENOG4107VRP	DNA repair exonuclease
AWM73_06360	ENOG4105WZB	UPF0342 protein
AWM73_06365	ENOG4105BZ4	penicillin-binding protein
AWM73_06370	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AWM73_06375	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
AWM73_06380	ENOG4105C5I	Dehydrogenase
AWM73_06385	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AWM73_06390	ENOG4105C5Y	PTS System
AWM73_06395	ENOG4108HKT	sucrose-6-phosphate hydrolase
AWM73_06400	ENOG4105ETE	Transcriptional regulator (LacI family
AWM73_06430	ENOG4105DU0	nucleoside hydrolase
AWM73_06450	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AWM73_06500	ENOG4105CAH	Chromate
AWM73_06590	ENOG4105II7	pyrroline-5-carboxylate reductase
AWM73_06595	ENOG4105G5W	regulator Fur family
AWM73_06600	ENOG4108V3A	UPF0421 protein
AWM73_06605	ENOG4108IUM	Glycogen debranching enzyme
AWM73_06615	ENOG4105EVI	UPF0374 protein
AWM73_06620	ENOG4105CEN	a g-specific adenine glycosylase
AWM73_06625	ENOG410902V	Modulates RecA activity (By similarity)
AWM73_06650	ENOG4105CMR	udp-glucose 4-epimerase
AWM73_06655	ENOG41068JE	domain protein
AWM73_06660	ENOG4107RBM	d-lactate dehydrogenase
AWM73_06665	ENOG4108URH	decarboxylase
AWM73_06680	ENOG4108UVJ	appr-1-p processing domain protein
AWM73_06695	ENOG4105DEN	Luciferase family
AWM73_06715	ENOG4105DZC	cytosine deaminase
AWM73_06730	ENOG4105C34	Pseudouridine synthase
AWM73_06750	ENOG4108IJ8	ABC transporter
AWM73_06765	ENOG4105CSM	endonuclease III
AWM73_06775	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AWM73_06780	ENOG4105F27	Major Facilitator
AWM73_06810	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AWM73_06820	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AWM73_06830	ENOG4108JJB	ABC transporter
AWM73_06835	ENOG4108JJB	ABC transporter
AWM73_06845	ENOG4108ZT0	50S ribosomal protein l17
AWM73_06850	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AWM73_06855	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AWM73_06865	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AWM73_06870	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AWM73_06875	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AWM73_06880	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AWM73_06885	ENOG41087RB	50S ribosomal protein L30
AWM73_06890	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AWM73_06895	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AWM73_06905	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AWM73_06910	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AWM73_06915	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AWM73_06930	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AWM73_06935	ENOG41082SA	50s ribosomal protein l29
AWM73_06940	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AWM73_06945	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AWM73_06950	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AWM73_06955	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AWM73_06960	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AWM73_06965	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AWM73_06970	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AWM73_06975	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AWM73_06980	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AWM73_06990	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AWM73_06995	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AWM73_07000	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AWM73_07005	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AWM73_07015	ENOG4105CRK	lysyL-tRNA synthetase
AWM73_07020	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AWM73_07025	ENOG4105C6T	cysteine synthase
AWM73_07030	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AWM73_07035	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AWM73_07040	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AWM73_07045	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AWM73_07050	ENOG41060GV	RNA binding s1 domain protein
AWM73_07060	ENOG41082I2	s4 domain protein
AWM73_07070	ENOG4108JA2	transcriptioN-repair coupling factor
AWM73_07075	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AWM73_07080	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AWM73_07100	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AWM73_07130	ENOG4105CKK	Glycosyl transferase, family 2
AWM73_07135	ENOG4108ZIE	5 nucleotidase deoxy cytosolic type C
AWM73_07160	ENOG4105C37	(CBS) domain
AWM73_07170	ENOG4105DA5	(ABC) transporter
AWM73_07180	ENOG4107TXC	Transcriptional regulator
AWM73_07195	ENOG4108U5N	UPF0316 protein
AWM73_07200	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
AWM73_07205	ENOG4105C1J	atp-dependent rna helicase
AWM73_07210	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
AWM73_07215	ENOG4105CPF	Cell wall formation (By similarity)
AWM73_07230	ENOG4108Z6X	(sortase) family
AWM73_07235	ENOG41082DI	50s ribosomal protein l31
AWM73_07240	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AWM73_07245	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AWM73_07260	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
AWM73_07265	ENOG4105DCI	Phosphohydrolase
AWM73_07270	ENOG4105CHM	Aminotransferase
AWM73_07280	ENOG4107VFR	oxidoreductase
AWM73_07285	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AWM73_07295	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
AWM73_07300	ENOG4105VC4	domain protein
AWM73_07305	ENOG41060K3	Methyltransferase
AWM73_07310	ENOG41063V3	Involved in initiation control of chromosome replication (By similarity)
AWM73_07320	ENOG4105FA2	dna polymerase iii
AWM73_07325	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AWM73_07330	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AWM73_07335	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AWM73_07340	ENOG4105C6E	dna polymerase iii
AWM73_07350	ENOG4108Z6B	deaminase
AWM73_07355	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AWM73_07365	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AWM73_07370	ENOG4105KEX	transcriptional regulator, ctsr
AWM73_07375	ENOG4105PGM	cation diffusion facilitator family transporter
AWM73_07385	ENOG4105CJ1	ABC, transporter
AWM73_07435	ENOG4108WBT	adenosyltransferase
AWM73_07445	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AWM73_07450	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AWM73_07455	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AWM73_07460	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
AWM73_07465	ENOG4105CAG	UPF0210 protein
AWM73_07490	ENOG4108IJ7	Glycine betaine
AWM73_07495	ENOG4107Y49	methyltransferase
AWM73_07500	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
AWM73_07505	ENOG4105D7K	pfkb domain protein
AWM73_07510	ENOG4108M60	Transcriptional regulator
AWM73_07515	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AWM73_07520	ENOG4108VZM	50s ribosomal protein L10
AWM73_07525	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AWM73_07530	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AWM73_07540	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AWM73_07555	ENOG4105M0M	Tetracycline resistance protein
AWM73_07560	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AWM73_07565	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AWM73_07570	ENOG4105C8N	cysteinyl-tRNA synthetase
AWM73_07580	ENOG4105DAP	Nicotinate phosphoribosyltransferase
AWM73_07615	ENOG410667J	hydrolase
AWM73_07635	ENOG4105K78	MarR family Transcriptional regulator
AWM73_07640	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AWM73_07645	ENOG4105CI1	PTS System
AWM73_07650	ENOG4105D1Q	UPF0246 protein
AWM73_07675	ENOG4105DR4	Methyltransferase
AWM73_07685	ENOG4105BZU	Histidine kinase
AWM73_07690	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AWM73_07705	ENOG4105CIE	May be required for sporulation (By similarity)
AWM73_07710	ENOG4105CHW	UPF0052 protein
AWM73_07715	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AWM73_07740	ENOG4105C3M	thioredoxin reductase
AWM73_07750	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AWM73_07755	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AWM73_07760	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
AWM73_07775	ENOG4105EYH	Exonuclease
AWM73_07780	ENOG4107RFY	SbcCD D subunit
AWM73_07785	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AWM73_07845	ENOG4105D9N	nucleoside
AWM73_07850	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
AWM73_07860	ENOG4105EA8	2-Nitropropane dioxygenase
AWM73_07865	ENOG4107R7Y	intracellular protease Pfpi family
AWM73_07870	ENOG4105VI0	Pts system, glucitol sorbitol-specific
AWM73_07875	ENOG4105DZY	Pts system, glucitol sorbitol-specific
AWM73_07880	ENOG410787A	Pts system, glucitol sorbitol-specific
AWM73_07885	ENOG4105J92	DNA-binding transcriptional activator GutM
AWM73_07895	ENOG4105CHR	reductase
AWM73_07900	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
AWM73_07910	ENOG4105DJV	ribulose-phosphate 3-epimerase
AWM73_07920	ENOG4105CPQ	Dehydrogenase
AWM73_07925	ENOG4105DT3	PTS system, galactitol-specific IIc component
AWM73_07930	ENOG41090UW	PTS System
AWM73_07945	ENOG4107QM2	Aldo Keto reductase
AWM73_07950	ENOG4107RHR	regulatoR
AWM73_07955	ENOG4105CHR	reductase
AWM73_07965	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AWM73_07970	ENOG4105D2N	Aldolase
AWM73_07975	ENOG4105DKT	Transcriptional regulator
AWM73_07980	ENOG4105F3R	pts system mannose fructose sorbose family iid
AWM73_07985	ENOG4105ETZ	PTS System
AWM73_07990	ENOG4108IQ3	PTS system
AWM73_07995	ENOG4108EQA	pts system
AWM73_08000	ENOG41080HJ	6-phospho 3-hexuloisomerase
AWM73_08005	ENOG4105DJV	ribulose-phosphate 3-epimerase
AWM73_08010	ENOG4105E98	transcriptional regulator DeoR family
AWM73_08020	ENOG4105F3R	pts system mannose fructose sorbose family iid
AWM73_08025	ENOG4105ETZ	PTS System
AWM73_08030	ENOG4108IQ3	PTS system
AWM73_08040	ENOG4105D4T	Citrate transporter
AWM73_08045	ENOG4105FF2	Type I DHQase
AWM73_08050	ENOG4105EMV	Major Facilitator
AWM73_08055	ENOG4105E2X	shikimate dehydrogenase
AWM73_08060	ENOG4105C5Q	Transcriptional regulator
AWM73_08065	ENOG4107EFR	Flavocytochrome c
AWM73_08070	ENOG4105C5I	Dehydrogenase
AWM73_08080	ENOG4108MRH	transcriptional regulatory protein
AWM73_08095	ENOG4105C5Y	PTS System
AWM73_08100	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AWM73_08110	ENOG4105CHR	reductase
AWM73_08115	ENOG4107EFR	Flavocytochrome c
AWM73_08210	ENOG4105MZU	cell filamentation protein
AWM73_08225	ENOG4108UMI	ABC transporter, permease
AWM73_08230	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AWM73_08235	ENOG4105D01	(LipO)protein
AWM73_08250	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
AWM73_08255	ENOG4105GIG	
AWM73_08270	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
AWM73_08275	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
AWM73_08280	ENOG4105EA8	2-Nitropropane dioxygenase
AWM73_08285	ENOG4105CGU	Enoyl-CoA hydratase
AWM73_08290	ENOG4105DUM	transcriptional regulator, lysR family
AWM73_08295	ENOG4105ECY	inositol monophosphatase
AWM73_08300	ENOG4105K63	Thioredoxin
AWM73_08305	ENOG4105C3M	thioredoxin reductase
AWM73_08310	ENOG4108TVJ	Nitroreductase
AWM73_08320	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AWM73_08335	ENOG4105DE4	1-phosphofructokinase
AWM73_08340	ENOG4105E98	transcriptional regulator DeoR family
AWM73_08345	ENOG4105E66	phosphoriboisomerase A
AWM73_08360	ENOG4105DT3	PTS system, galactitol-specific IIc component
AWM73_08365	ENOG4105DJV	ribulose-phosphate 3-epimerase
AWM73_08370	ENOG4107EFR	Flavocytochrome c
AWM73_08375	ENOG4107QPK	)-transporter
AWM73_08390	ENOG4105C5Q	Transcriptional regulator
AWM73_08395	ENOG4105KV4	Transcriptional regulator
AWM73_08400	ENOG4105C87	Aminotransferase class I and II
AWM73_08440	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AWM73_08450	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AWM73_08460	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
AWM73_08465	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AWM73_08470	ENOG4108IY8	ABC, transporter
AWM73_08480	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
AWM73_08485	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AWM73_08490	ENOG4105CUC	YeeE YedE family protein
AWM73_08495	ENOG4105DY9	regulatoR
AWM73_08510	ENOG4105BZU	Histidine kinase
AWM73_08525	ENOG4105W2C	Glycosyl transferase
AWM73_08540	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
AWM73_08550	ENOG4105C3G	gtp-binding protein
AWM73_08555	ENOG4105VDK	protein, conserved in bacteria
AWM73_08560	ENOG4105FA0	parb-like partition protein
AWM73_08565	ENOG4107QJE	Chromosome Partitioning Protein
AWM73_08575	ENOG4108TV1	Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor (By similarity)
AWM73_08595	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
AWM73_08605	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AWM73_08610	ENOG4108HRK	Histidine kinase
AWM73_08615	ENOG4105DY9	regulatoR
AWM73_08625	ENOG41067MG	lrgb family
AWM73_08660	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AWM73_08665	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AWM73_08675	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AWM73_08685	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AWM73_08690	ENOG4108JJB	ABC transporter
AWM73_08705	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
AWM73_08710	ENOG4108JU6	CBS domain protein
AWM73_08715	ENOG4105C59	p-type ATPase
AWM73_08720	ENOG4105C02	permease
AWM73_08725	ENOG4105K8R	UPF0145 protein
AWM73_08740	ENOG4105F3R	pts system mannose fructose sorbose family iid
AWM73_08745	ENOG4105ETZ	PTS System
AWM73_08760	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AWM73_08765	ENOG4105C1G	acyl-Coa dehydrogenase
AWM73_08770	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AWM73_08775	ENOG4108Z7S	Single-stranded nucleic acid binding R3H domain-containing protein
AWM73_08780	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AWM73_08785	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AWM73_08800	ENOG4105CPP	Dehydrogenase, E1 component
AWM73_08805	ENOG4105C7S	Dehydrogenase
AWM73_08825	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AWM73_08830	ENOG4105CQB	FAD linked oxidase domain protein
AWM73_08835	ENOG410848D	S4 domain protein YaaA
AWM73_08840	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AWM73_08845	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AWM73_08850	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AWM73_08855	ENOG4108IUX	(ABC) transporter
AWM73_08860	ENOG4105RHA	ABC transporter, permease
AWM73_08875	ENOG4105HDK	L-asparaginase
AWM73_08885	ENOG4105CH2	amidohydrolase
AWM73_08890	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AWM73_08895	ENOG4108UUM	single-stranded DNA-binding protein
AWM73_08900	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AWM73_08920	ENOG41083J0	(ABC) transporter
AWM73_08925	ENOG4105C4B	ABC transporter, permease
AWM73_08930	ENOG4105C4B	ABC transporter, permease
AWM73_08935	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AWM73_08940	ENOG4105CDU	Replicative dna helicase
AWM73_08955	ENOG4105C0A	alcohol dehydrogenase
AWM73_08965	ENOG4105DAA	L-lactate
AWM73_08975	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AWM73_08985	ENOG4105CI2	imidazolone-5-propionate hydrolase