locus-tag	class	description
AWM74_00010	ENOG4105VSD	UPF0346 protein
AWM74_00025	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AWM74_00030	ENOG4105C5H	ABC transporter
AWM74_00040	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AWM74_00045	ENOG4107S9R	deoxycytidine triphosphate deaminase
AWM74_00055	ENOG4105CPQ	Dehydrogenase
AWM74_00060	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
AWM74_00075	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AWM74_00080	ENOG4105CFG	Acts as a chaperone (By similarity)
AWM74_00085	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AWM74_00090	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AWM74_00095	ENOG4105CH2	amidohydrolase
AWM74_00100	ENOG4105DTN	riboflavin biosynthesis protein ribF
AWM74_00105	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AWM74_00110	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AWM74_00115	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AWM74_00120	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AWM74_00125	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AWM74_00130	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AWM74_00135	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AWM74_00140	ENOG4107104	thymidine kinase
AWM74_00145	ENOG4105DMS	mur ligase
AWM74_00150	ENOG4105F1K	Glutamine amidotransferase
AWM74_00155	ENOG4108RAV	Conserved protein
AWM74_00165	ENOG4105BZ1	(ABC) transporter
AWM74_00175	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
AWM74_00180	ENOG4107XWI	flavin reductase domain protein, FMN-binding
AWM74_00190	ENOG4105UIB	(ABC) transporter
AWM74_00195	ENOG4108JQ9	ABC transporter
AWM74_00200	ENOG4105DIH	basic membrane
AWM74_00205	ENOG4105CI1	PTS System
AWM74_00210	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AWM74_00215	ENOG4105CFH	Aspartokinase
AWM74_00220	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
AWM74_00230	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AWM74_00235	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AWM74_00265	ENOG41080XP	Cbs domain
AWM74_00270	ENOG4105CP9	extracellular ligand-binding receptor
AWM74_00295	ENOG4105DC8	reductase
AWM74_00315	ENOG4105C75	arginyL-tRNA synthetase
AWM74_00330	ENOG4105D01	(LipO)protein
AWM74_00335	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AWM74_00345	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AWM74_00350	ENOG4105CNI	cell division protein FtsW
AWM74_00355	ENOG4107U9T	Pfam:Ribonuclease_BN
AWM74_00405	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AWM74_00410	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AWM74_00415	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AWM74_00420	ENOG4105DX0	Hemolysin A
AWM74_00430	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AWM74_00435	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AWM74_00440	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AWM74_00445	ENOG4105M7K	Involved in the transcription termination process (By similarity)
AWM74_00455	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AWM74_00460	ENOG4105DC7	peptidase M24
AWM74_00530	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
AWM74_00535	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
AWM74_00540	ENOG4106C6A	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AWM74_00545	ENOG4105CDY	transcriptional regulatory protein
AWM74_00550	ENOG4106ZEE	Diacylglycerol kinase
AWM74_00555	ENOG4105BZ4	penicillin-binding protein
AWM74_00560	ENOG4105E2A	Dehydrogenase
AWM74_00565	ENOG4107Z5F	Aminotransferase class IV
AWM74_00570	ENOG4105CV8	reductase
AWM74_00580	ENOG4105VUC	UPF0237 protein
AWM74_00585	ENOG4105PNM	synthesis protein
AWM74_00590	ENOG4105ETE	Transcriptional regulator (LacI family
AWM74_00605	ENOG4105D8X	mechanosensitive ion channel
AWM74_00610	ENOG4105M59	Phosphodiesterase, mj0936 family
AWM74_00615	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AWM74_00630	ENOG4105K63	Thioredoxin
AWM74_00635	ENOG4105C98	muts2 protein
AWM74_00650	ENOG4105E5Q	amino acid AbC transporter
AWM74_00670	ENOG4105BZU	Histidine kinase
AWM74_00685	ENOG4105ERH	Fumarylacetoacetate hydrolase
AWM74_00690	ENOG4108R96	Methyltransferase, YaeB family
AWM74_00700	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
AWM74_00705	ENOG4107XJU	UPF0178 protein
AWM74_00715	ENOG4105C5I	Dehydrogenase
AWM74_00720	ENOG4105E5Q	amino acid AbC transporter
AWM74_00725	ENOG4108Z66	YbaK ebsC protein
AWM74_00735	ENOG410667J	hydrolase
AWM74_00750	ENOG4106KNT	transcriptional regulator
AWM74_00755	ENOG4105D9R	oxidoreductase
AWM74_00760	ENOG4105D9R	oxidoreductase
AWM74_00765	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
AWM74_00780	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
AWM74_00805	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
AWM74_00810	ENOG4105DFH	Transport of potassium into the cell (By similarity)
AWM74_00840	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
AWM74_00845	ENOG4105C5B	carbamate kinase
AWM74_00850	ENOG4105N16	Protein of unknown function (DUF2877)
AWM74_00860	ENOG4105S0E	allantoin catabolism protein
AWM74_00870	ENOG4108UMN	azlc family
AWM74_00875	ENOG4108JJB	ABC transporter
AWM74_00880	ENOG4105D4A	Cell wall formation (By similarity)
AWM74_00895	ENOG4105K8N	protein family UPF0079, ATPase
AWM74_00900	ENOG4108IJ2	phosphate acetyltransferase
AWM74_00910	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AWM74_00915	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AWM74_00930	ENOG4108RWN	rrna methyltransferase
AWM74_00955	ENOG4105C8T	Leucyl-tRNA synthetase
AWM74_00960	ENOG4105E2X	shikimate dehydrogenase
AWM74_00970	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
AWM74_00975	ENOG4107X35	defense response to bacterium
AWM74_00990	ENOG4105VEQ	Cold shock protein
AWM74_00995	ENOG4105W5Q	DNA repair protein (RadC
AWM74_01005	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
AWM74_01010	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AWM74_01015	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AWM74_01020	ENOG4105WZW	rhodanese family
AWM74_01025	ENOG4105DKQ	ROK family
AWM74_01030	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AWM74_01035	ENOG4107ZXI	Rhomboid family
AWM74_01045	ENOG4107RF6	penicillin-binding protein
AWM74_01055	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AWM74_01070	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
AWM74_01075	ENOG4105DIH	basic membrane
AWM74_01080	ENOG4105SFS	phosphoesterase RecJ domain protein
AWM74_01105	ENOG4105VIE	preprotein translocase, subunit YajC
AWM74_01110	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AWM74_01125	ENOG4105DI5	UPF0365 protein
AWM74_01135	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AWM74_01145	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AWM74_01155	ENOG4105EQK	-acetyltransferase
AWM74_01165	ENOG4105ENX	hydrolase
AWM74_01170	ENOG4105VUF	Transcriptional regulator
AWM74_01180	ENOG4105KVH	Transcriptional regulator
AWM74_01185	ENOG4105XTG	Pfam:DUF156
AWM74_01190	ENOG4105WZW	rhodanese family
AWM74_01195	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AWM74_01205	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AWM74_01210	ENOG4105BZ1	(ABC) transporter
AWM74_01215	ENOG4105BZ1	(ABC) transporter
AWM74_01225	ENOG4105C12	Phosphoribosylglycinamide synthetase
AWM74_01230	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AWM74_01235	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AWM74_01240	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AWM74_01250	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AWM74_01260	ENOG4107T2D	Phosphoribosylaminoimidazolesuccinocarboxamide synthase
AWM74_01280	ENOG4105DET	Rhamnulokinase
AWM74_01290	ENOG4105CS2	ec 3.2.1.21
AWM74_01295	ENOG4105VCP	PTS System
AWM74_01305	ENOG4105EMD	TRANSCRIPTIONal
AWM74_01315	ENOG4105CS2	ec 3.2.1.21
AWM74_01320	ENOG4105CK1	PTS System
AWM74_01325	ENOG4105VUF	Transcriptional regulator
AWM74_01330	ENOG4105CPC	Aldo Keto reductase
AWM74_01335	ENOG4105D9R	oxidoreductase
AWM74_01345	ENOG4105CMQ	Chloride channel
AWM74_01350	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AWM74_01365	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AWM74_01370	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AWM74_01375	ENOG4105VB6	UPF0109 protein
AWM74_01380	ENOG4105K5M	30s ribosomal protein S16
AWM74_01390	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
AWM74_01400	ENOG4108ZQX	ybak prolyl-trna synthetase
AWM74_01405	ENOG4105EVU	fructokinase
AWM74_01410	ENOG4108JQ1	Dehydrogenase
AWM74_01415	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AWM74_01430	ENOG4105EWM	Histidine kinase
AWM74_01435	ENOG4105C19	ABC transporter
AWM74_01455	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AWM74_01460	ENOG410667J	hydrolase
AWM74_01465	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AWM74_01470	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AWM74_01475	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AWM74_01480	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
AWM74_01485	ENOG4105CB5	ATP-dependent DNA helicase recG
AWM74_01490	ENOG4105DEN	Luciferase family
AWM74_01515	ENOG4105CGK	Exodeoxyribonuclease III
AWM74_01520	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AWM74_01535	ENOG4105CI1	PTS System
AWM74_01545	ENOG4105CK1	PTS System
AWM74_01550	ENOG4105CS2	ec 3.2.1.21
AWM74_01555	ENOG4108TZY	GntR Family Transcriptional Regulator
AWM74_01575	ENOG4108EKI	Dehydrogenase
AWM74_01580	ENOG4105F1A	Pyruvate formate-lyase
AWM74_01585	ENOG4105C6N	Formate acetyltransferase
AWM74_01590	ENOG4105VG1	fes assembly suf system protein
AWM74_01655	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
AWM74_01675	ENOG4105K64	Glycosyl transferase, family 2
AWM74_01680	ENOG4105K64	Glycosyl transferase, family 2
AWM74_01700	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
AWM74_01710	ENOG4105C5E	polysaccharide biosynthesis protein
AWM74_01725	ENOG4105D3Q	Sugar transferase
AWM74_01735	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
AWM74_01740	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AWM74_01765	ENOG4105FE1	phytoene synthase
AWM74_01780	ENOG4105DP4	dak2 domain fusion protein ylov
AWM74_01785	ENOG4108ZAA	Alkaline-shock protein
AWM74_01790	ENOG4105VB9	50S ribosomal protein l28
AWM74_01795	ENOG4105FJ0	thiamine
AWM74_01800	ENOG4105DJV	ribulose-phosphate 3-epimerase
AWM74_01805	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AWM74_01810	ENOG4105D9P	serine threonine protein kinase
AWM74_01815	ENOG4108ZF3	Phosphatase
AWM74_01820	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AWM74_01825	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AWM74_01830	ENOG4105C25	Primosomal protein n'
AWM74_01835	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AWM74_01840	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AWM74_01845	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AWM74_01855	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AWM74_01870	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AWM74_01875	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AWM74_01880	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AWM74_01885	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AWM74_01895	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AWM74_01900	ENOG4105TQK	DNA polymerase iii, delta' subunit
AWM74_01910	ENOG4105KQC	Competence protein
AWM74_01915	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AWM74_01920	ENOG4106H78	methyltransferase
AWM74_01940	ENOG4105IJJ	transcriptional regulator, crp fnr family
AWM74_01945	ENOG4108WPJ	Ferritin-like domain
AWM74_01965	ENOG4105WUC	UPF0298 protein
AWM74_01970	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
AWM74_01975	ENOG4105CI1	PTS System
AWM74_01985	ENOG4105CNI	cell division protein FtsW
AWM74_01990	ENOG4105CI3	gtp-binding protein typa
AWM74_01995	ENOG4105ECY	inositol monophosphatase
AWM74_02000	ENOG4105WBI	UPF0223 protein
AWM74_02005	ENOG4105D01	(LipO)protein
AWM74_02010	ENOG4105W4W	Transcriptional regulator
AWM74_02015	ENOG4105CT4	transporter
AWM74_02035	ENOG4105CK5	oxidoreductase
AWM74_02040	ENOG41063TF	transcriptional regulator (AraC
AWM74_02055	ENOG4105C7S	Dehydrogenase
AWM74_02060	ENOG4105CPP	Dehydrogenase, E1 component
AWM74_02065	ENOG4107RUY	(E1 component), alpha subunit
AWM74_02070	ENOG4107YB9	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AWM74_02075	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AWM74_02080	ENOG4105D98	threonine synthase
AWM74_02085	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AWM74_02105	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
AWM74_02110	ENOG4105D2H	Uronic isomerase
AWM74_02120	ENOG4108UHU	Aldolase
AWM74_02130	ENOG4105DMW	Dehydrogenase reductase
AWM74_02140	ENOG4105E66	phosphoriboisomerase A
AWM74_02145	ENOG4107QSE	Dipeptidase
AWM74_02155	ENOG4105DRP	amino acid AbC transporter
AWM74_02160	ENOG4105EAD	ABC transporter
AWM74_02165	ENOG4105CT1	(ABC) transporter
AWM74_02200	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AWM74_02210	ENOG4105C83	adenylosuccinate lyase
AWM74_02245	ENOG4105C72	UPF0176 protein
AWM74_02250	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AWM74_02255	ENOG4105C7J	ABC transporter, permease
AWM74_02270	ENOG4108UZE	carboxy-peptidase
AWM74_02275	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AWM74_02280	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AWM74_02285	ENOG4105HDK	L-asparaginase
AWM74_02290	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
AWM74_02300	ENOG4108QV3	biosynthesis protein
AWM74_02315	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
AWM74_02320	ENOG4108Z4K	mutator MutT protein
AWM74_02330	ENOG4105EPR	degv family
AWM74_02345	ENOG4105ZT7	DNA-entry nuclease
AWM74_02355	ENOG4108RVA	ribokinase
AWM74_02360	ENOG4108KGH	TRANSCRIPTIONal
AWM74_02365	ENOG4108KGH	TRANSCRIPTIONal
AWM74_02380	ENOG4105NQC	Flavodoxin
AWM74_02385	ENOG4105C88	aminopeptidase
AWM74_02400	ENOG4105CKK	Glycosyl transferase, family 2
AWM74_02435	ENOG4107RA4	Glycosyl transferase (Group 1
AWM74_02445	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AWM74_02455	ENOG4105DFT	pur operon repressor
AWM74_02465	ENOG4105FDK	ABC transporter
AWM74_02470	ENOG4105DSE	periplasmic solute binding protein
AWM74_02475	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AWM74_02480	ENOG4105W42	Veg protein
AWM74_02485	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AWM74_02495	ENOG4105F8V	Hydrolase, tatD family
AWM74_02500	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AWM74_02520	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
AWM74_02525	ENOG4105CFC	Transporter
AWM74_02540	ENOG4105C5F	glutamine synthetase
AWM74_02575	ENOG4105CHM	Aminotransferase
AWM74_02580	ENOG4108ZB6	transcriptional regulator AsnC family
AWM74_02600	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AWM74_02615	ENOG4105DZR	Type I site-specific deoxyribonuclease
AWM74_02625	ENOG4105CVR	type I restriction-modification system
AWM74_02630	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AWM74_02635	ENOG4105CZN	Potassium uptake protein
AWM74_02640	ENOG4107ZYR	domain protein
AWM74_02645	ENOG4105C0H	protease
AWM74_02650	ENOG4105Q2H	domain protein
AWM74_02670	ENOG4105BZU	Histidine kinase
AWM74_02675	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AWM74_02695	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
AWM74_02700	ENOG4108MXZ	Esterase
AWM74_02705	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AWM74_02710	ENOG4105C02	permease
AWM74_02735	ENOG4105DEN	Luciferase family
AWM74_02745	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AWM74_02750	ENOG4107RWR	Sodium hydrogen exchanger
AWM74_02755	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AWM74_02775	ENOG4107FQX	Alpha-acetolactate decarboxylase
AWM74_02785	ENOG4108J5H	Homocysteine s-methyltransferase
AWM74_02790	ENOG4108IQI	permease
AWM74_02795	ENOG4108URH	decarboxylase
AWM74_02810	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AWM74_02815	ENOG4108W15	Protein of unknown function (DUF1456)
AWM74_02825	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
AWM74_02835	ENOG4105D2M	Aldolase
AWM74_02850	ENOG4105DE4	1-phosphofructokinase
AWM74_02855	ENOG4105E98	transcriptional regulator DeoR family
AWM74_02860	ENOG4105DT3	PTS system, galactitol-specific IIc component
AWM74_02880	ENOG4105CH6	catalase
AWM74_02885	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AWM74_02890	ENOG4105WAB	arsR family transcriptional regulator
AWM74_02905	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AWM74_02910	ENOG4108UW5	maltose o-acetyltransferase
AWM74_02915	ENOG4108W5M	transcriptional regulator
AWM74_02920	ENOG4108YBP	pseudouridine synthase
AWM74_02935	ENOG4105CS2	ec 3.2.1.21
AWM74_02940	ENOG4105CK1	PTS System
AWM74_02950	ENOG4108TZY	GntR Family Transcriptional Regulator
AWM74_02960	ENOG4105VZJ	PTS System
AWM74_02965	ENOG4105VCP	PTS System
AWM74_02990	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AWM74_02995	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AWM74_03000	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
AWM74_03005	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AWM74_03010	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AWM74_03015	ENOG4105DDQ	anthranilate synthase
AWM74_03020	ENOG4105CRQ	synthase (Component I)
AWM74_03070	ENOG4108Z40	Transcriptional regulator
AWM74_03085	ENOG4105CGZ	zinc metallopeptidase
AWM74_03095	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
AWM74_03105	ENOG41086D8	Transcriptional regulator
AWM74_03115	ENOG41079CX	
AWM74_03135	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AWM74_03140	ENOG4107ZGM	malolactic fermentation system
AWM74_03150	ENOG41067MG	lrgb family
AWM74_03165	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
AWM74_03175	ENOG4105RNB	
AWM74_03180	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
AWM74_03185	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AWM74_03190	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AWM74_03205	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AWM74_03210	ENOG4105C4R	Atp-dependent dna helicase
AWM74_03220	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
AWM74_03225	ENOG4108IV0	ABC, transporter
AWM74_03230	ENOG4105C0Z	ABC transporter
AWM74_03235	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
AWM74_03240	ENOG4105C32	Amino acid ABC transporter (Permease)
AWM74_03245	ENOG4105CP9	extracellular ligand-binding receptor
AWM74_03255	ENOG4105CP9	extracellular ligand-binding receptor
AWM74_03265	ENOG4105CGH	5'-nucleotidase
AWM74_03275	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
AWM74_03280	ENOG4107QP7	CoA-transferase subunit A
AWM74_03285	ENOG4105C1G	acyl-Coa dehydrogenase
AWM74_03295	ENOG4105DQ6	Transposase
AWM74_03315	ENOG4105C4W	S-formylglutathione hydrolase
AWM74_03325	ENOG4105DR4	Methyltransferase
AWM74_03335	ENOG4105BZU	Histidine kinase
AWM74_03340	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AWM74_03345	ENOG41082AV	single-stranded DNA-binding protein
AWM74_03355	ENOG4105CIE	May be required for sporulation (By similarity)
AWM74_03360	ENOG4105CHW	UPF0052 protein
AWM74_03365	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AWM74_03375	ENOG4105C3M	thioredoxin reductase
AWM74_03380	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AWM74_03385	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AWM74_03390	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AWM74_03395	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
AWM74_03405	ENOG41067S9	phage shock protein C, PspC
AWM74_03420	ENOG4105EYH	Exonuclease
AWM74_03430	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AWM74_03435	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AWM74_03440	ENOG4105E2Z	phosphate ABC transporter (Permease
AWM74_03445	ENOG4105C8U	phosphate abc transporter
AWM74_03450	ENOG4107S17	Phosphate-binding protein
AWM74_03455	ENOG4105BZU	Histidine kinase
AWM74_03460	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AWM74_03465	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AWM74_03470	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AWM74_03490	ENOG4105EPR	degv family
AWM74_03495	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AWM74_03500	ENOG4105CQB	FAD linked oxidase domain protein
AWM74_03515	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
AWM74_03520	ENOG4105DAP	Nicotinate phosphoribosyltransferase
AWM74_03535	ENOG4105E5Q	amino acid AbC transporter
AWM74_03540	ENOG4108YYH	Nadph-dependent fmn reductase
AWM74_03550	ENOG4105E5Q	amino acid AbC transporter
AWM74_03555	ENOG4105CH7	arginosuccinase
AWM74_03565	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AWM74_03570	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AWM74_03580	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
AWM74_03585	ENOG4105C5H	ABC transporter
AWM74_03600	ENOG4105CHU	acetyl-coa acetyltransferase
AWM74_03605	ENOG4105C8F	Beta-lactamase domain protein
AWM74_03675	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AWM74_03680	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
AWM74_03685	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
AWM74_03720	ENOG4108Z6B	deaminase
AWM74_03725	ENOG4105C5Y	PTS System
AWM74_03730	ENOG4105CG3	alpha amylase, catalytic region
AWM74_03745	ENOG4107414	GntR family transcriptional regulator
AWM74_03755	ENOG4105CQC	Prephenate dehydratase
AWM74_03765	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AWM74_03770	ENOG4105KEX	transcriptional regulator, ctsr
AWM74_03775	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AWM74_03780	ENOG4105D4T	Citrate transporter
AWM74_03785	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
AWM74_03790	ENOG4105W2C	Glycosyl transferase
AWM74_03850	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
AWM74_03855	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
AWM74_03860	ENOG4105FKQ	transcriptional regulator
AWM74_03865	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
AWM74_03880	ENOG4105CK5	oxidoreductase
AWM74_03885	ENOG4108IJ9	(ABC) transporter
AWM74_03890	ENOG4108VP7	maltodextrose utilization protein MalA
AWM74_03895	ENOG4105EG2	ABC transporter, permease
AWM74_03900	ENOG4105D56	permease protein
AWM74_03905	ENOG4107FKK	extracellular solute-binding protein family 1
AWM74_03910	ENOG4108IUK	alpha amylase, catalytic
AWM74_03915	ENOG4105CI1	PTS System
AWM74_03930	ENOG4108Q3X	Transcriptional regulator
AWM74_03935	ENOG4105F8D	glycoside hydrolase family 4
AWM74_03940	ENOG4105CI1	PTS System
AWM74_03980	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AWM74_03985	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
AWM74_03990	ENOG4108U7W	acetyltransferase
AWM74_03995	ENOG41072GX	Peptidase M22 Glycoprotease
AWM74_04000	ENOG4105CT4	transporter
AWM74_04005	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
AWM74_04010	ENOG4105FBA	Phospholipase Carboxylesterase
AWM74_04015	ENOG4105VPS	UPF0291 protein
AWM74_04020	ENOG4105CS2	ec 3.2.1.21
AWM74_04025	ENOG4105C5Y	PTS System
AWM74_04035	ENOG4105C7B	Threonine dehydratase
AWM74_04040	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AWM74_04045	ENOG4108ZP8	Acetolactate synthase small subunit
AWM74_04050	ENOG4105C7K	acetolactate synthase
AWM74_04055	ENOG4105DKW	ABC transporter
AWM74_04065	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AWM74_04085	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AWM74_04095	ENOG410667J	hydrolase
AWM74_04105	ENOG4105C7N	Xanthine uracil vitamin C permease
AWM74_04115	ENOG4107ZXU	DSBA oxidoreductase
AWM74_04140	ENOG4105CHR	reductase
AWM74_04150	ENOG4105D01	(LipO)protein
AWM74_04160	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
AWM74_04165	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
AWM74_04170	ENOG4105ETD	TRANSCRIPTIONal
AWM74_04175	ENOG4105CTS	PTS system mannitol-specific
AWM74_04180	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
AWM74_04185	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AWM74_04190	ENOG4108QY0	Membrane
AWM74_04195	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AWM74_04215	ENOG4105I08	Pseudouridine synthase
AWM74_04230	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AWM74_04240	ENOG4105K7K	Transcriptional regulator
AWM74_04245	ENOG4107TXC	Transcriptional regulator
AWM74_04250	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AWM74_04260	ENOG4105VBF	alkaline shock protein
AWM74_04280	ENOG4105F8D	glycoside hydrolase family 4
AWM74_04285	ENOG4108Q3X	Transcriptional regulator
AWM74_04295	ENOG4108KXM	LysR family Transcriptional regulator
AWM74_04300	ENOG4105C28	cystathionine
AWM74_04305	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
AWM74_04315	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AWM74_04320	ENOG4107YZX	Universal stress protein
AWM74_04340	ENOG4105KWG	Pfam:DUF1696
AWM74_04350	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
AWM74_04400	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AWM74_04405	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AWM74_04420	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AWM74_04425	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AWM74_04445	ENOG4105C3G	gtp-binding protein
AWM74_04450	ENOG4105VDK	protein, conserved in bacteria
AWM74_04455	ENOG4105FA0	parb-like partition protein
AWM74_04460	ENOG4107QJE	Chromosome Partitioning Protein
AWM74_04465	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AWM74_04475	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AWM74_04480	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AWM74_04495	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
AWM74_04500	ENOG4105ETD	TRANSCRIPTIONal
AWM74_04505	ENOG4105CTS	PTS system mannitol-specific
AWM74_04515	ENOG4105CPN	adenine deaminase
AWM74_04525	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AWM74_04535	ENOG4105VG0	50S ribosomal protein l34
AWM74_04545	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AWM74_04550	ENOG410848D	S4 domain protein YaaA
AWM74_04555	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AWM74_04560	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AWM74_04565	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AWM74_04570	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AWM74_04575	ENOG4108UUM	single-stranded DNA-binding protein
AWM74_04580	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AWM74_04585	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
AWM74_04595	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AWM74_04605	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AWM74_04610	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AWM74_04615	ENOG4108JQ7	(ABC) transporter
AWM74_04630	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AWM74_04635	ENOG4105CDU	Replicative dna helicase
AWM74_04650	ENOG4105C59	p-type ATPase
AWM74_04665	ENOG4108JJB	ABC transporter
AWM74_04675	ENOG4105ETU	transcriptional activator (TenA
AWM74_04685	ENOG4107R7Y	intracellular protease Pfpi family
AWM74_04690	ENOG4107PP3	Acetylornithine deacetylase
AWM74_04695	ENOG4105C5Y	PTS System
AWM74_04700	ENOG4105ZMH	deoxynucleoside kinase
AWM74_04715	ENOG4107WD4	Releases the N-terminal proline from various substrates (By similarity)
AWM74_04730	ENOG41067MG	lrgb family
AWM74_04735	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AWM74_04750	ENOG4105ZMH	deoxynucleoside kinase
AWM74_04755	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
AWM74_04775	ENOG4105VG1	fes assembly suf system protein
AWM74_04785	ENOG4108UTZ	Dihydroxyacetone kinase
AWM74_04790	ENOG4105CMT	Dihydroxyacetone kinase
AWM74_04795	ENOG4105VDH	Dihydroxyacetone kinase
AWM74_04800	ENOG4105C87	Aminotransferase class I and II
AWM74_04810	ENOG4105KV4	Transcriptional regulator
AWM74_04830	ENOG4105ETZ	PTS System
AWM74_04835	ENOG4105F3R	pts system mannose fructose sorbose family iid
AWM74_04845	ENOG4105DG6	mannose-6-phosphate isomerase
AWM74_04850	ENOG4105TMB	Formate nitrite transporter
AWM74_04865	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AWM74_04895	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
AWM74_04920	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AWM74_04925	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AWM74_04930	ENOG4105CTP	PilT protein domain protein
AWM74_04935	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AWM74_04945	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
AWM74_04950	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AWM74_04960	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
AWM74_04965	ENOG4105C2W	permease
AWM74_04970	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
AWM74_04975	ENOG4105E90	ABC transporter
AWM74_04980	ENOG4108IJ8	ABC transporter
AWM74_04990	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AWM74_04995	ENOG4105D01	(LipO)protein
AWM74_05000	ENOG4106ETB	IIa component
AWM74_05010	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
AWM74_05015	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AWM74_05020	ENOG4105C8N	cysteinyl-tRNA synthetase
AWM74_05025	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AWM74_05030	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AWM74_05045	ENOG4105CY2	Citrate transporter
AWM74_05055	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AWM74_05065	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AWM74_05070	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AWM74_05075	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AWM74_05080	ENOG4108VZM	50s ribosomal protein L10
AWM74_05085	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AWM74_05100	ENOG4108HW4	amino acid AbC transporter
AWM74_05105	ENOG4105EAB	amino acid AbC transporter
AWM74_05115	ENOG4105DIK	(ABC) transporter
AWM74_05120	ENOG4107RPQ	ABC transporter
AWM74_05125	ENOG4105CC5	ABC transporter
AWM74_05135	ENOG4105CS2	ec 3.2.1.21
AWM74_05145	ENOG4105C5Y	PTS System
AWM74_05150	ENOG4105CS2	ec 3.2.1.21
AWM74_05155	ENOG4107Y49	methyltransferase
AWM74_05160	ENOG4108IJ7	Glycine betaine
AWM74_05180	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AWM74_05185	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AWM74_05190	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AWM74_05235	ENOG4105DRS	transport system, permease
AWM74_05245	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
AWM74_05250	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AWM74_05255	ENOG4105C6E	dna polymerase iii
AWM74_05260	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AWM74_05265	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AWM74_05270	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AWM74_05275	ENOG4105FA2	dna polymerase iii
AWM74_05280	ENOG4105WT3	Transcriptional regulator
AWM74_05300	ENOG4105DA5	(ABC) transporter
AWM74_05335	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AWM74_05345	ENOG41063V3	Involved in initiation control of chromosome replication (By similarity)
AWM74_05350	ENOG41060K3	Methyltransferase
AWM74_05355	ENOG4105VC4	domain protein
AWM74_05360	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
AWM74_05370	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AWM74_05375	ENOG4105DXD	2-methylcitrate dehydratase
AWM74_05390	ENOG4107VFR	oxidoreductase
AWM74_05400	ENOG4105CHM	Aminotransferase
AWM74_05405	ENOG4107Y80	Major Facilitator superfamily
AWM74_05410	ENOG4105DCI	Phosphohydrolase
AWM74_05415	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
AWM74_05425	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
AWM74_05430	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AWM74_05435	ENOG4108M1Z	surface protein
AWM74_05440	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AWM74_05450	ENOG4107RGD	Major Facilitator superfamily
AWM74_05455	ENOG4105WD1	Membrane
AWM74_05480	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AWM74_05485	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AWM74_05490	ENOG41082DI	50s ribosomal protein l31
AWM74_05495	ENOG4105KME	endoribonuclease L-psp
AWM74_05500	ENOG4105WQG	acetyltransferase
AWM74_05505	ENOG4105C6T	cysteine synthase
AWM74_05510	ENOG4105D7W	serine acetyltransferase
AWM74_05515	ENOG4108Z6X	(sortase) family
AWM74_05535	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
AWM74_05545	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
AWM74_05555	ENOG4105E90	ABC transporter
AWM74_05570	ENOG4108U5N	UPF0316 protein
AWM74_05575	ENOG410807C	QueT transporter
AWM74_05580	ENOG4105C5X	domain protein
AWM74_05590	ENOG4105D17	glycoside hydrolase, family 3 domain protein
AWM74_05595	ENOG4105C37	(CBS) domain
AWM74_05600	ENOG4108VQJ	O-methyltransferase
AWM74_05635	ENOG4105CSR	polyphosphate kinase 2
AWM74_05640	ENOG4107B2H	carbonic anhydrase
AWM74_05645	ENOG4105GGE	ribonuclease
AWM74_05650	ENOG41067XF	inhibitor
AWM74_05675	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AWM74_05680	ENOG4105DIN	metallophosphoesterase
AWM74_05685	ENOG4105FDU	atp-dependent rna helicase
AWM74_05695	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AWM74_05705	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AWM74_05710	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AWM74_05715	ENOG4108JA2	transcriptioN-repair coupling factor
AWM74_05725	ENOG41082I2	s4 domain protein
AWM74_05735	ENOG41060GV	RNA binding s1 domain protein
AWM74_05740	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AWM74_05745	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AWM74_05750	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AWM74_05755	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AWM74_05765	ENOG4105KTU	Transcriptional regulator, arsr family
AWM74_05770	ENOG4105CRK	lysyL-tRNA synthetase
AWM74_05775	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AWM74_05780	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AWM74_05785	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AWM74_05790	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AWM74_05800	ENOG4108JJB	ABC transporter
AWM74_05820	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AWM74_05825	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AWM74_05830	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AWM74_05835	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AWM74_05840	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AWM74_05845	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AWM74_05850	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AWM74_05855	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AWM74_05860	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AWM74_05865	ENOG41082SA	50s ribosomal protein l29
AWM74_05870	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AWM74_05875	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AWM74_05880	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AWM74_05885	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AWM74_05890	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AWM74_05895	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AWM74_05900	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AWM74_05905	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AWM74_05910	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AWM74_05915	ENOG4105VPB	50S ribosomal protein L30
AWM74_05920	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AWM74_05925	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AWM74_05935	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AWM74_05945	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AWM74_05950	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AWM74_05955	ENOG4108ZT0	50S ribosomal protein l17
AWM74_05960	ENOG4105EXC	Acyl-transferase
AWM74_05970	ENOG4108JJB	ABC transporter
AWM74_05975	ENOG4108JJB	ABC transporter
AWM74_05985	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AWM74_05990	ENOG4105FF2	Type I DHQase
AWM74_05995	ENOG4105RKW	reductase (By
AWM74_06025	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AWM74_06030	ENOG4108UJD	30S ribosomal protein S9
AWM74_06045	ENOG4108VK3	Cupin 2 Conserved Barrel Domain Protein
AWM74_06050	ENOG4105MDS	4-oxalocrotonate tautomerase
AWM74_06065	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AWM74_06070	ENOG4108R6K	riboflavin synthase, subunit alpha
AWM74_06075	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AWM74_06090	ENOG4105X1N	Glycosyl transferase family 8
AWM74_06095	ENOG4105FDP	GntR family transcriptional regulator
AWM74_06100	ENOG4105CXK	mandelate racemase muconate lactonizing
AWM74_06105	ENOG4105C5Y	PTS System
AWM74_06120	ENOG4105ST3	Transcriptional regulator
AWM74_06140	ENOG4105CS2	ec 3.2.1.21
AWM74_06150	ENOG4105KVH	Transcriptional regulator
AWM74_06170	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
AWM74_06175	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AWM74_06180	ENOG4105DWF	phosphomethylpyrimidine kinase
AWM74_06190	ENOG4107QQ0	gntp family
AWM74_06195	ENOG4105BZW	Glycerate kinase
AWM74_06200	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
AWM74_06210	ENOG4105CP9	extracellular ligand-binding receptor
AWM74_06215	ENOG4105CE4	GlcNAc 6-P deacetylase
AWM74_06220	ENOG4108JQ7	(ABC) transporter
AWM74_06240	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
AWM74_06250	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AWM74_06255	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AWM74_06260	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AWM74_06265	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AWM74_06270	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AWM74_06275	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AWM74_06280	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AWM74_06285	ENOG4105CR4	methylisocitrate lyase
AWM74_06300	ENOG4108S3Y	transcriptional regulator
AWM74_06305	ENOG4108V06	Glutathione peroxidase
AWM74_06310	ENOG4105DSE	periplasmic solute binding protein
AWM74_06315	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
AWM74_06355	ENOG410807C	QueT transporter
AWM74_06370	ENOG4105C59	p-type ATPase
AWM74_06380	ENOG4107QN2	dihydrolipoyl dehydrogenase
AWM74_06390	ENOG4105DEN	Luciferase family
AWM74_06410	ENOG4108HW4	amino acid AbC transporter
AWM74_06415	ENOG4108HW3	(ABC) transporter
AWM74_06425	ENOG4108MRH	transcriptional regulatory protein
AWM74_06450	ENOG4105EVN	Prephenate dehydrogenase
AWM74_06460	ENOG4105CMR	udp-glucose 4-epimerase
AWM74_06490	ENOG4105CEN	a g-specific adenine glycosylase
AWM74_06495	ENOG4105EVI	UPF0374 protein
AWM74_06505	ENOG4108IUM	Glycogen debranching enzyme
AWM74_06510	ENOG4107NBY	Membrane
AWM74_06515	ENOG4105II7	pyrroline-5-carboxylate reductase
AWM74_06525	ENOG4107QM2	Aldo Keto reductase
AWM74_06640	ENOG4105DEN	Luciferase family
AWM74_06645	ENOG4105D01	(LipO)protein
AWM74_06650	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AWM74_06655	ENOG4105CVJ	phosphoglycerate mutase
AWM74_06660	ENOG4105CS2	ec 3.2.1.21
AWM74_06665	ENOG4108S3Y	transcriptional regulator
AWM74_06670	ENOG4105VZJ	PTS System
AWM74_06685	ENOG4105CK1	PTS System
AWM74_06690	ENOG4105CPC	Aldo Keto reductase
AWM74_06695	ENOG4108K4B	hydrolase
AWM74_06705	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AWM74_06710	ENOG4105C5Y	PTS System
AWM74_06715	ENOG4105CS2	ec 3.2.1.21
AWM74_06735	ENOG4108IDU	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AWM74_06740	ENOG4108UMI	ABC transporter, permease
AWM74_06745	ENOG4105D01	(LipO)protein
AWM74_06750	ENOG4108UZX	fmn reductase
AWM74_06755	ENOG4108XSB	acetyltransferase, (GNAT) family
AWM74_06760	ENOG4108HW4	amino acid AbC transporter
AWM74_06780	ENOG4105E5Q	amino acid AbC transporter
AWM74_06785	ENOG4105CDA	abc transporter atp-binding protein
AWM74_06790	ENOG4105DCF	alanine dehydrogenase
AWM74_06795	ENOG4108K88	Membrane
AWM74_06805	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AWM74_06815	ENOG4105BZ4	penicillin-binding protein
AWM74_06820	ENOG4105WZB	UPF0342 protein
AWM74_06825	ENOG4107VRP	DNA repair exonuclease
AWM74_06830	ENOG4106D4I	domain protein
AWM74_06835	ENOG4105EQI	Metal Dependent Phosphohydrolase
AWM74_06845	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
AWM74_06850	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
AWM74_06860	ENOG4105K59	histidine triad (HIT) protein
AWM74_06880	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AWM74_06890	ENOG4108VDD	TRNA binding domain protein
AWM74_06900	ENOG4105DFU	Cell wall formation (By similarity)
AWM74_06915	ENOG4105G6Z	alkaline phosphatase
AWM74_06935	ENOG4108RG0	uracil-dna glycosylase
AWM74_06940	ENOG4105DEU	major facilitator superfamily
AWM74_06945	ENOG4105CHF	Glutathione S-transferase
AWM74_06955	ENOG4105EUJ	GTP cyclohydrolase i
AWM74_06960	ENOG4105EEI	dihydropteroate synthase
AWM74_06965	ENOG4105KRF	dihydroneopterin aldolase
AWM74_06970	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AWM74_06975	ENOG4105NAE	bifunctional deaminase-reductase domain protein
AWM74_06980	ENOG4105CVJ	phosphoglycerate mutase
AWM74_06985	ENOG4107PP3	Acetylornithine deacetylase
AWM74_06995	ENOG4105C2M	dna polymerase I
AWM74_07000	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AWM74_07010	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AWM74_07035	ENOG4105VBF	alkaline shock protein
AWM74_07040	ENOG4105C22	threonyL-tRNA synthetase
AWM74_07050	ENOG4108R3E	Dna-3-methyladenine glycosylase i
AWM74_07055	ENOG4105D01	(LipO)protein
AWM74_07065	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AWM74_07070	ENOG4105VJV	50s ribosomal protein L35
AWM74_07075	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AWM74_07080	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AWM74_07085	ENOG4108UMI	ABC transporter, permease
AWM74_07090	ENOG4105D01	(LipO)protein
AWM74_07100	ENOG4105DF9	Lipoate-protein, ligase
AWM74_07105	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
AWM74_07110	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
AWM74_07115	ENOG4105C31	Tryptophanyl-tRNA synthetase
AWM74_07150	ENOG4105EMS	pseudouridine synthase
AWM74_07155	ENOG4105CJW	magnesium transporter
AWM74_07165	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
AWM74_07170	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AWM74_07185	ENOG41082BV	acetyltransferase
AWM74_07190	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AWM74_07195	ENOG4105DUM	transcriptional regulator, lysR family
AWM74_07200	ENOG4105HMI	Membrane
AWM74_07205	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AWM74_07210	ENOG4105KRI	phosphocarrier protein (HPr
AWM74_07215	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AWM74_07220	ENOG4105BZF	Glycosyl transferase (Group 1
AWM74_07225	ENOG4107IN1	Protein of unknown function (DUF1797)
AWM74_07230	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AWM74_07235	ENOG4105D6E	homoserine dehydrogenase
AWM74_07240	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AWM74_07245	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
AWM74_07250	ENOG4105CQW	ribosome biogenesis GTPase YqeH
AWM74_07255	ENOG410812S	Rna-binding protein
AWM74_07260	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AWM74_07275	ENOG4105DXX	methyltransferase
AWM74_07280	ENOG4105CDE	UPF0348 protein
AWM74_07285	ENOG4105KNH	Nucleic acid-binding protein
AWM74_07290	ENOG41067VY	50S ribosomal protein L32
AWM74_07300	ENOG4108V6E	Cell division protein mraZ
AWM74_07305	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AWM74_07315	ENOG4105CJN	penicillin-binding protein
AWM74_07320	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AWM74_07325	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AWM74_07330	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AWM74_07335	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
AWM74_07340	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AWM74_07350	ENOG4105DFA	alanine racemase domain protein
AWM74_07355	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
AWM74_07365	ENOG4105DBK	s4 domain protein
AWM74_07375	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AWM74_07385	ENOG4107BMA	Transglycosylase associated protein
AWM74_07390	ENOG4105CDW	Resistance protein
AWM74_07400	ENOG4108YZ4	nudix hydrolase
AWM74_07415	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AWM74_07420	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
AWM74_07430	ENOG4105C3J	Cysteine desulfurase
AWM74_07435	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
AWM74_07440	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
AWM74_07450	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
AWM74_07455	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AWM74_07465	ENOG4108UW5	maltose o-acetyltransferase
AWM74_07470	ENOG4105C7K	acetolactate synthase
AWM74_07480	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
AWM74_07485	ENOG410855V	Acylphosphatase
AWM74_07495	ENOG4105CNU	cell division protein FtsK
AWM74_07500	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AWM74_07510	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AWM74_07515	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
AWM74_07540	ENOG4105C5Y	PTS System
AWM74_07545	ENOG4105CS2	ec 3.2.1.21
AWM74_07560	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
AWM74_07565	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AWM74_07570	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AWM74_07575	ENOG4105E0X	reductase
AWM74_07580	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AWM74_07590	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AWM74_07595	ENOG4105C0B	DNA polymerase III (alpha subunit)
AWM74_07600	ENOG4105CTQ	phosphohexokinase
AWM74_07605	ENOG4105CA9	Pyruvate kinase
AWM74_07610	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AWM74_07620	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AWM74_07625	ENOG4105QNR	S1 RNA binding domain protein
AWM74_07635	ENOG4108IUX	(ABC) transporter
AWM74_07640	ENOG4105RHA	ABC transporter, permease
AWM74_07650	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
AWM74_07655	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AWM74_07660	ENOG4105FE9	pseudouridine synthase
AWM74_07665	ENOG4108SAX	Membrane
AWM74_07675	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AWM74_07690	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AWM74_07695	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AWM74_07700	ENOG4105K70	DNA-binding protein
AWM74_07705	ENOG4105C5Y	PTS System
AWM74_07715	ENOG4105ETE	Transcriptional regulator (LacI family
AWM74_07730	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AWM74_07735	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AWM74_07740	ENOG4105DVT	helicase
AWM74_07760	ENOG4105CSM	endonuclease III
AWM74_07765	ENOG41090MY	MarR family Transcriptional regulator
AWM74_07770	ENOG4107R8B	5'-nucleotidase
AWM74_07775	ENOG4105MMD	transcriptional regulator
AWM74_07780	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
AWM74_07790	ENOG4105CAY	ferredoxin--nadp reductase
AWM74_07800	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AWM74_07810	ENOG4107QYV	phosphohexose isomerase
AWM74_07945	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AWM74_07955	ENOG4105E5Q	amino acid AbC transporter
AWM74_07960	ENOG4105CDA	abc transporter atp-binding protein
AWM74_07965	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AWM74_07970	ENOG4105X36	(ribosomal) protein
AWM74_07985	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AWM74_07995	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AWM74_08000	ENOG4105C5Y	PTS System
AWM74_08020	ENOG4107YZX	Universal stress protein
AWM74_08030	ENOG4105D1H	recombination factor protein RarA
AWM74_08035	ENOG4105D9M	gamma-glutamylcysteine synthetase
AWM74_08040	ENOG4105C3J	Cysteine desulfurase
AWM74_08050	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AWM74_08055	ENOG4105C7H	Helicase, RecD TraA family
AWM74_08060	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AWM74_08070	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AWM74_08075	ENOG4105VPH	UPF0473 protein
AWM74_08080	ENOG41062ES	Transcriptional regulator
AWM74_08085	ENOG4105ECB	domain protein
AWM74_08100	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AWM74_08115	ENOG4105WH1	Two component transcriptional regulator luxr family
AWM74_08120	ENOG4105CN5	Metallo-Beta-Lactamase
AWM74_08125	ENOG4106EHS	UPF0356 protein
AWM74_08130	ENOG4108QEG	Membrane
AWM74_08135	ENOG4108UT2	hemolysin iii
AWM74_08150	ENOG4105EPR	degv family
AWM74_08170	ENOG41083J0	(ABC) transporter
AWM74_08175	ENOG4105C4B	ABC transporter, permease
AWM74_08185	ENOG4105CS9	pantothenic acid kinase
AWM74_08190	ENOG4105C02	permease
AWM74_08195	ENOG4105BZ1	(ABC) transporter
AWM74_08200	ENOG4105BZ1	(ABC) transporter
AWM74_08205	ENOG4105C5H	ABC transporter
AWM74_08210	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AWM74_08220	ENOG4105J7I	hydrolase
AWM74_08235	ENOG4105MTF	NrdI protein
AWM74_08240	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AWM74_08245	ENOG4107R25	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AWM74_08250	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
AWM74_08255	ENOG4105BZ4	penicillin-binding protein
AWM74_08260	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
AWM74_08265	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AWM74_08270	ENOG4105DU0	nucleoside hydrolase
AWM74_08275	ENOG4105D9N	nucleoside
AWM74_08280	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AWM74_08285	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AWM74_08290	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AWM74_08295	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AWM74_08310	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AWM74_08315	ENOG4105CAS	nag kinase
AWM74_08320	ENOG4105DBV	ornithine carbamoyltransferase
AWM74_08325	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AWM74_08330	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
AWM74_08335	ENOG4105C8Y	Acetylornithine aminotransferase
AWM74_08365	ENOG4105EGD	dinuclear metal center protein, YbgI family
AWM74_08370	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
AWM74_08375	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AWM74_08380	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
AWM74_08390	ENOG4108B1Q	Ribonuclease
AWM74_08395	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AWM74_08400	ENOG4105C34	Pseudouridine synthase
AWM74_08405	ENOG4105VXM	UPF0154 protein
AWM74_08410	ENOG4105BZ1	(ABC) transporter
AWM74_08415	ENOG4105BZ1	(ABC) transporter
AWM74_08420	ENOG4105F6E	Acyl-transferase
AWM74_08425	ENOG4108REF	Sporulation integral membrane protein ytvi
AWM74_08440	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AWM74_08445	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AWM74_08450	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AWM74_08455	ENOG4105US7	Histidine kinase
AWM74_08460	ENOG4108STX	response regulator
AWM74_08480	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AWM74_08485	ENOG4105KNE	Phosphatidate cytidylyltransferase
AWM74_08490	ENOG4105DZP	Membrane-associated zinc metalloprotease
AWM74_08495	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
AWM74_08515	ENOG4105CHV	Transcription elongation factor NusA
AWM74_08520	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
AWM74_08530	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AWM74_08535	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AWM74_08545	ENOG4105KA3	membrAne
AWM74_08555	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AWM74_08570	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AWM74_08575	ENOG4105BZA	Phosphoglycerate kinase
AWM74_08580	ENOG4105CP7	Triose-phosphate isomerase
AWM74_08585	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AWM74_08590	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AWM74_08595	ENOG4108J59	Extracellular solute-binding protein, family 5
AWM74_08600	ENOG4108J59	Extracellular solute-binding protein, family 5
AWM74_08610	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AWM74_08615	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AWM74_08625	ENOG4108JQ7	(ABC) transporter
AWM74_08640	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AWM74_08645	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AWM74_08650	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
AWM74_08655	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AWM74_08675	ENOG4105DZC	cytosine deaminase
AWM74_08690	ENOG4105DU0	nucleoside hydrolase
AWM74_08710	ENOG4105EA8	2-Nitropropane dioxygenase
AWM74_08715	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AWM74_08720	ENOG4105CHR	reductase
AWM74_08725	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AWM74_08735	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AWM74_08740	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AWM74_08745	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AWM74_08765	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AWM74_08775	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
AWM74_08785	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AWM74_08790	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AWM74_08795	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AWM74_08800	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AWM74_08810	ENOG4105CUT	histidyl-tRNA synthetase
AWM74_08815	ENOG4105C9M	aspartyl-trna synthetase
AWM74_08830	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
AWM74_08840	ENOG4105CD3	dihydroorotase
AWM74_08845	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
AWM74_08850	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AWM74_08860	ENOG4105N80	Ferric uptake regulator, Fur family
AWM74_08870	ENOG4105KTH	gatB Yqey
AWM74_08875	ENOG4105CHR	reductase
AWM74_08890	ENOG4105C9A	Phoh family
AWM74_08895	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AWM74_08905	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AWM74_08910	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
AWM74_08915	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
AWM74_08920	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AWM74_08930	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AWM74_08935	ENOG4105EMU	Dehydrogenase
AWM74_08940	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AWM74_08945	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AWM74_08950	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AWM74_08960	ENOG4105F23	Fibronectin-binding protein
AWM74_08970	ENOG4105C7J	ABC transporter, permease
AWM74_08990	ENOG4107R37	Glutamate dehydrogenase
AWM74_08995	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AWM74_09005	ENOG4105E98	transcriptional regulator DeoR family
AWM74_09010	ENOG4105DE4	1-phosphofructokinase
AWM74_09015	ENOG4105DM4	PTS System
AWM74_09020	ENOG4105BZ1	(ABC) transporter
AWM74_09025	ENOG4105BZ1	(ABC) transporter
AWM74_09035	ENOG4105EAB	amino acid AbC transporter
AWM74_09040	ENOG4105EAB	amino acid AbC transporter
AWM74_09045	ENOG4108PGP	mmge prpd family protein
AWM74_09050	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
AWM74_09055	ENOG4108XSB	acetyltransferase, (GNAT) family
AWM74_09060	ENOG4108HW4	amino acid AbC transporter
AWM74_09075	ENOG4108R6W	Transcriptional regulator, ARAC family
AWM74_09080	ENOG4105DME	alpha-galactosidase
AWM74_09085	ENOG4107YY3	extracellular solute-binding protein family 1
AWM74_09100	ENOG4107RK0	Sucrose phosphorylase
AWM74_09105	ENOG4108IJ9	(ABC) transporter
AWM74_09115	ENOG4105CQ4	Transcriptional regulator
AWM74_09120	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
AWM74_09145	ENOG4105CT4	transporter
AWM74_09155	ENOG4105C10	Electron transfer flavoprotein
AWM74_09160	ENOG4105BZJ	Electron transfer flavoprotein
AWM74_09165	ENOG4105C1G	acyl-Coa dehydrogenase
AWM74_09190	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AWM74_09200	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AWM74_09205	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AWM74_09210	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AWM74_09215	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AWM74_09220	ENOG4105C1A	potassium transporter peripheral membrane
AWM74_09225	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
AWM74_09235	ENOG4105CHU	acetyl-coa acetyltransferase
AWM74_09245	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AWM74_09250	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
AWM74_09255	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AWM74_09260	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AWM74_09265	ENOG4105C79	DNA protecting protein DprA
AWM74_09270	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AWM74_09275	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
AWM74_09280	ENOG4105C3F	Signal peptidase i