locus-tag	class	description
IMX20_00010	COG0592	DNA-directed DNA polymerase activity
IMX20_00015	COG2501	S4 domain
IMX20_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IMX20_00025	COG0187	DNA topoisomerase II activity
IMX20_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMX20_00035	COG0360	Binds together with S18 to 16S ribosomal RNA
IMX20_00040	COG0629	single-stranded DNA binding
IMX20_00045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IMX20_00050	COG0346	lactoylglutathione lyase activity
IMX20_00055	COG0371	Dehydrogenase
IMX20_00060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IMX20_00070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMX20_00075	COG0601	transmembrane transport
IMX20_00080	COG4608	Belongs to the ABC transporter superfamily
IMX20_00095	COG0359	binds to the 23S rRNA
IMX20_00100	COG0305	Participates in initiation and elongation during chromosome replication
IMX20_00115	COG2217	Heavy metal translocating P-type atpase
IMX20_00130	COG1122	ATPase activity
IMX20_00140	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IMX20_00150	COG0693	protein deglycase activity
IMX20_00155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IMX20_00160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX20_00160	COG1263	PTS System
IMX20_00160	COG2190	(PTS) system
IMX20_00165	COG1428	Deoxynucleoside kinase
IMX20_00180	COG0596	Alpha beta hydrolase
IMX20_00195	COG1346	cytolysis
IMX20_00200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IMX20_00210	COG1418	mRNA catabolic process
IMX20_00215	COG1428	Deoxynucleoside kinase
IMX20_00220	COG0602	queuosine metabolic process
IMX20_00225	COG1328	CTP reductase activity
IMX20_00240	COG2151	metal-sulfur cluster biosynthetic enzyme
IMX20_00245	COG2217	Heavy metal translocating P-type atpase
IMX20_00250	COG1461	Dihydroxyacetone kinase
IMX20_00255	COG2376	Dihydroxyacetone kinase
IMX20_00260	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
IMX20_00265	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IMX20_00270	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IMX20_00275	COG0789	Transcriptional regulator
IMX20_00295	COG3715	PTS system
IMX20_00300	COG3716	PTS system mannose fructose sorbose family IID component
IMX20_00310	COG1482	cell wall glycoprotein biosynthetic process
IMX20_00315	COG2116	formate transmembrane transporter activity
IMX20_00325	COG1496	oxidoreductase activity
IMX20_00350	COG0756	dUTP diphosphatase activity
IMX20_00355	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IMX20_00360	COG4956	integral membrane protein (PIN domain superfamily)
IMX20_00365	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IMX20_00375	COG1780	Probably involved in ribonucleotide reductase function
IMX20_00380	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMX20_00390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IMX20_00395	COG2233	PERMEase
IMX20_00405	COG1174	glycine betaine transport
IMX20_00410	COG0517	IMP dehydrogenase activity
IMX20_00410	COG1125	glycine betaine transport
IMX20_00415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IMX20_00430	COG2124	cytochrome p450
IMX20_00455	COG0456	acetyltransferase
IMX20_00485	COG2003	Belongs to the UPF0758 family
IMX20_00500	COG0488	(ABC) transporter
IMX20_00515	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IMX20_00550	COG2217	Heavy metal translocating P-type atpase
IMX20_00555	COG0640	Transcriptional regulator
IMX20_00570	COG1307	EDD domain protein, DegV family
IMX20_00590	COG1523	belongs to the glycosyl hydrolase 13 family
IMX20_00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IMX20_00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMX20_00635	COG3688	RNA-binding protein containing a PIN domain
IMX20_00650	COG2610	gluconate transmembrane transporter activity
IMX20_00655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IMX20_00665	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IMX20_00675	COG0250	Participates in transcription elongation, termination and antitermination
IMX20_00685	COG0704	Plays a role in the regulation of phosphate uptake
IMX20_00690	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IMX20_00695	COG0081	regulation of translation
IMX20_00705	COG0222	ribosome binding
IMX20_00715	COG1121	(ABC) transporter
IMX20_00720	COG1321	iron dependent repressor
IMX20_00720	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IMX20_00725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IMX20_00730	COG2813	Specifically methylates the guanine in position
IMX20_00735	COG3448	diguanylate cyclase activity
IMX20_00735	COG4175	Glycine betaine
IMX20_00755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMX20_00760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMX20_00765	COG0135	phosphoribosylanthranilate isomerase activity
IMX20_00775	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IMX20_00780	COG0446	pyridine nucleotide-disulphide oxidoreductase
IMX20_00790	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IMX20_00830	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IMX20_00840	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IMX20_00845	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IMX20_00850	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IMX20_00860	COG0470	DNA polymerase III
IMX20_00865	COG1396	sequence-specific DNA binding
IMX20_00875	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IMX20_00875	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IMX20_00885	COG4467	Involved in initiation control of chromosome replication
IMX20_00890	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IMX20_00895	COG2827	Endonuclease containing a URI domain
IMX20_00900	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IMX20_00910	COG1970	mechanosensitive ion channel activity
IMX20_00915	COG2079	MmgE PrpD family protein
IMX20_00925	COG0372	Belongs to the citrate synthase family
IMX20_00930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IMX20_00940	COG0436	Aminotransferase
IMX20_00945	COG2814	Major facilitator Superfamily
IMX20_00950	COG1078	dGTPase activity
IMX20_00955	COG0095	Lipoate-protein ligase
IMX20_00965	COG3343	RNA polymerase activity
IMX20_00970	COG0504	CTP synthase activity
IMX20_00980	COG0284	orotidine-5'-phosphate decarboxylase activity
IMX20_00990	COG2814	Major facilitator Superfamily
IMX20_00995	COG2832	Protein of unknown function (DUF454)
IMX20_01020	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IMX20_01025	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IMX20_01030	COG0254	rRNA binding
IMX20_01040	COG0251	oxidation-reduction process
IMX20_01045	COG0456	acetyltransferase
IMX20_01050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IMX20_01060	COG3764	Sortase (surface protein transpeptidase)
IMX20_01075	COG1181	Belongs to the D-alanine--D-alanine ligase family
IMX20_01080	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IMX20_01090	COG0736	holo-[acyl-carrier-protein] synthase activity
IMX20_01100	COG1174	glycine betaine transport
IMX20_01115	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
IMX20_01120	COG4708	membrane
IMX20_01125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IMX20_01140	COG1253	flavin adenine dinucleotide binding
IMX20_01145	COG4122	O-methyltransferase activity
IMX20_01195	COG2326	polyphosphate kinase activity
IMX20_01200	COG0288	reversible hydration of carbon dioxide
IMX20_01205	COG4290	ribonuclease
IMX20_01210	COG2732	(Barnase) inhibitor
IMX20_01240	COG0322	excinuclease ABC activity
IMX20_01245	COG1408	metallophosphoesterase
IMX20_01250	COG0513	Belongs to the DEAD box helicase family
IMX20_01260	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IMX20_01270	COG0039	L-malate dehydrogenase activity
IMX20_01275	COG0193	aminoacyl-tRNA hydrolase activity
IMX20_01280	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IMX20_01285	COG2244	polysaccharide biosynthetic process
IMX20_01290	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IMX20_01300	COG1098	S1 RNA binding domain
IMX20_01305	COG0037	tRNA processing
IMX20_01310	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IMX20_01315	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMX20_01320	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IMX20_01330	COG0640	Transcriptional regulator
IMX20_01335	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IMX20_01340	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IMX20_01345	COG0049	tRNA binding
IMX20_01350	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IMX20_01355	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IMX20_01375	COG0505	Belongs to the CarA family
IMX20_01380	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IMX20_01405	COG0051	transcription antitermination factor activity, RNA binding
IMX20_01410	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IMX20_01415	COG0088	Forms part of the polypeptide exit tunnel
IMX20_01420	COG0089	rRNA binding
IMX20_01435	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IMX20_01440	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IMX20_01445	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IMX20_01450	COG0255	Belongs to the universal ribosomal protein uL29 family
IMX20_01455	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IMX20_01460	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IMX20_01465	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IMX20_01475	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IMX20_01480	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IMX20_01485	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IMX20_01490	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IMX20_01495	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IMX20_01500	COG1841	ribosomal large subunit assembly
IMX20_01515	COG0563	adenylate kinase activity
IMX20_01530	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IMX20_01535	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IMX20_01540	COG0202	RNA polymerase activity
IMX20_01545	COG0203	ribosomal protein L17
IMX20_01550	COG2755	lipolytic protein G-D-S-L family
IMX20_01550	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IMX20_01560	COG1122	ATPase activity
IMX20_01565	COG1122	ATPase activity
IMX20_01585	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IMX20_01600	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IMX20_01605	COG0583	DNA-binding transcription factor activity
IMX20_01610	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IMX20_01615	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IMX20_01625	COG2217	Heavy metal translocating P-type atpase
IMX20_01630	COG3759	membrane
IMX20_01640	COG0662	Cupin 2, conserved barrel domain protein
IMX20_01645	COG1942	4-Oxalocrotonate Tautomerase
IMX20_01675	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IMX20_01675	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IMX20_01715	COG1309	transcriptional regulator
IMX20_01720	COG0657	acetylesterase activity
IMX20_01725	COG2723	6-phospho-beta-galactosidase activity
IMX20_01735	COG1733	regulation of RNA biosynthetic process
IMX20_01745	COG3339	Conserved Protein
IMX20_01760	COG0352	thiamine-phosphate diphosphorylase activity
IMX20_01765	COG0351	phosphomethylpyrimidine kinase
IMX20_01775	COG1929	Belongs to the glycerate kinase type-1 family
IMX20_01810	COG1725	Transcriptional regulator
IMX20_01815	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IMX20_01820	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IMX20_01825	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IMX20_01830	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IMX20_01835	COG0131	Imidazoleglycerol-phosphate dehydratase
IMX20_01840	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IMX20_01845	COG0107	imidazoleglycerol-phosphate synthase activity
IMX20_01850	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IMX20_01850	COG0140	phosphoribosyl-ATP diphosphatase activity
IMX20_01855	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IMX20_01870	COG2188	Transcriptional regulator
IMX20_01875	COG0386	Belongs to the glutathione peroxidase family
IMX20_01910	COG0656	L-ascorbic acid biosynthetic process
IMX20_01935	COG0702	epimerase
IMX20_01940	COG4708	membrane
IMX20_01955	COG2217	Heavy metal translocating P-type atpase
IMX20_01965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMX20_01975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMX20_01980	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IMX20_01985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMX20_01990	COG1126	abc transporter atp-binding protein
IMX20_01995	COG0765	amino acid transport
IMX20_02000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMX20_02005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMX20_02010	COG4565	transcriptional regulatory protein
IMX20_02015	COG3290	protein histidine kinase activity
IMX20_02020	COG3493	citrate carrier protein
IMX20_02030	COG4166	transmembrane transport
IMX20_02040	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IMX20_02065	COG2137	regulation of response to DNA damage stimulus
IMX20_02070	COG1194	a g-specific adenine glycosylase
IMX20_02075	COG3557	Belongs to the UPF0374 family
IMX20_02085	COG1523	belongs to the glycosyl hydrolase 13 family
IMX20_02090	COG4129	membrane
IMX20_02095	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IMX20_02105	COG0667	Aldo Keto reductase
IMX20_02215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMX20_02220	COG1464	Belongs to the NlpA lipoprotein family
IMX20_02225	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IMX20_02230	COG0406	alpha-ribazole phosphatase activity
IMX20_02235	COG2723	6-phospho-beta-galactosidase activity
IMX20_02240	COG2188	Transcriptional regulator
IMX20_02245	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IMX20_02260	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IMX20_02265	COG0667	Aldo Keto reductase
IMX20_02270	COG0561	phosphatase activity
IMX20_02280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMX20_02285	COG2190	(PTS) system
IMX20_02285	COG1263	PTS System
IMX20_02285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX20_02290	COG2723	6-phospho-beta-galactosidase activity
IMX20_02310	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IMX20_02315	COG2011	ABC-type metal ion transport system permease component
IMX20_02320	COG1464	Belongs to the NlpA lipoprotein family
IMX20_02325	COG0431	NADPH-dependent FMN reductase
IMX20_02335	COG0765	amino acid transport
IMX20_02340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMX20_02345	COG0765	amino acid transport
IMX20_02350	COG1126	abc transporter atp-binding protein
IMX20_02355	COG0686	Belongs to the AlaDH PNT family
IMX20_02360	COG3949	Membrane
IMX20_02365	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IMX20_02375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IMX20_02380	COG3679	Belongs to the UPF0342 family
IMX20_02385	COG0420	3'-5' exonuclease activity
IMX20_02390	COG4717	serine-type aminopeptidase activity
IMX20_02405	COG0737	Belongs to the 5'-nucleotidase family
IMX20_02410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IMX20_02420	COG0537	adenosine 5'-monophosphoramidase activity
IMX20_02425	COG1131	(ABC) transporter
IMX20_02430	COG4473	ABC transporter
IMX20_02440	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IMX20_02450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMX20_02460	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IMX20_02475	COG1785	Belongs to the alkaline phosphatase family
IMX20_02500	COG1573	uracil-dna glycosylase
IMX20_02505	COG2270	Major facilitator Superfamily
IMX20_02525	COG0435	Glutathione S-transferase
IMX20_02535	COG0302	gtp cyclohydrolase
IMX20_02540	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IMX20_02545	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IMX20_02550	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IMX20_02555	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IMX20_02560	COG0406	alpha-ribazole phosphatase activity
IMX20_02565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IMX20_02575	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IMX20_02575	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IMX20_02580	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IMX20_02585	COG0237	dephospho-CoA kinase activity
IMX20_02600	COG1484	DNA-dependent DNA replication
IMX20_02615	COG1302	Protein conserved in bacteria
IMX20_02620	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IMX20_02630	COG2818	Glycosylase
IMX20_02635	COG1464	Belongs to the NlpA lipoprotein family
IMX20_02645	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IMX20_02655	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IMX20_02660	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IMX20_02665	COG2011	ABC-type metal ion transport system permease component
IMX20_02670	COG1464	Belongs to the NlpA lipoprotein family
IMX20_02680	COG0095	Lipoate-protein ligase
IMX20_02685	COG4862	establishment of competence for transformation
IMX20_02690	COG1393	Belongs to the ArsC family
IMX20_02695	COG0180	Tryptophanyl-tRNA synthetase
IMX20_02710	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IMX20_02720	COG2357	RelA SpoT domain protein
IMX20_02730	COG0564	pseudouridine synthase activity
IMX20_02735	COG2239	Acts as a magnesium transporter
IMX20_02745	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IMX20_02750	COG0105	UTP biosynthetic process
IMX20_02755	COG0625	glutathione transferase activity
IMX20_02770	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IMX20_02775	COG0583	DNA-binding transcription factor activity
IMX20_02785	COG0542	response to heat
IMX20_02790	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMX20_02800	COG0438	transferase activity, transferring glycosyl groups
IMX20_02805	COG4703	Protein of unknown function (DUF1797)
IMX20_02810	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IMX20_02815	COG0460	homoserine dehydrogenase
IMX20_02820	COG0083	homoserine kinase activity
IMX20_02825	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
IMX20_02830	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IMX20_02835	COG1534	Rna-binding protein
IMX20_02840	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IMX20_02845	COG1713	HD superfamily hydrolase involved in NAD metabolism
IMX20_02850	COG0799	negative regulation of ribosome biogenesis
IMX20_02855	COG2226	methyltransferase
IMX20_02860	COG1323	Belongs to the UPF0348 family
IMX20_02865	COG1399	metal-binding, possibly nucleic acid-binding protein
IMX20_02885	COG2001	Belongs to the MraZ family
IMX20_02900	COG0768	penicillin binding
IMX20_02905	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IMX20_02910	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IMX20_02915	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IMX20_02920	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IMX20_02925	COG0849	cell division
IMX20_02935	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IMX20_02950	COG2302	S4 RNA-binding domain
IMX20_02955	COG3599	regulation of cell shape
IMX20_02960	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IMX20_02970	COG2261	transglycosylase associated protein
IMX20_02975	COG3853	Toxic anion resistance protein (TelA)
IMX20_02985	COG0494	nUDIX hydrolase
IMX20_03000	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IMX20_03005	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IMX20_03010	COG1104	cysteine desulfurase activity
IMX20_03015	COG0301	tRNA thio-modification
IMX20_03020	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IMX20_03030	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IMX20_03035	COG0745	RESPONSE REGULATOR receiver
IMX20_03050	COG0028	Belongs to the TPP enzyme family
IMX20_03055	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IMX20_03060	COG0706	membrane insertase activity
IMX20_03065	COG1254	Belongs to the acylphosphatase family
IMX20_03075	COG1674	ftsk spoiiie
IMX20_03075	COG1280	lysine exporter protein (LysE YggA)
IMX20_03080	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IMX20_03090	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IMX20_03130	COG1914	H( )-stimulated, divalent metal cation uptake system
IMX20_03135	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IMX20_03140	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IMX20_03155	COG2255	four-way junction helicase activity
IMX20_03160	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IMX20_03165	COG0587	DNA-directed DNA polymerase activity
IMX20_03170	COG0205	6-phosphofructokinase activity
IMX20_03180	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IMX20_03190	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IMX20_03195	COG2996	Protein conserved in bacteria
IMX20_03205	COG4152	abc transporter atp-binding protein
IMX20_03210	COG1668	transmembrane transport
IMX20_03215	COG0456	acetyltransferase
IMX20_03220	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IMX20_03225	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IMX20_03230	COG1187	pseudouridine synthase activity
IMX20_03235	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IMX20_03245	COG0514	ATP-dependent DNA helicase (RecQ)
IMX20_03255	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IMX20_03265	COG0539	negative regulation of cytoplasmic translation
IMX20_03270	COG1160	GTP binding
IMX20_03285	COG1621	beta-fructofuranosidase activity
IMX20_03290	COG1609	Transcriptional regulator
IMX20_03305	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IMX20_03310	COG0617	tRNA 3'-terminal CCA addition
IMX20_03315	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IMX20_03315	COG1199	ATP-dependent helicase activity
IMX20_03335	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IMX20_03340	COG1846	Transcriptional regulator
IMX20_03345	COG0737	Belongs to the 5'-nucleotidase family
IMX20_03350	COG4470	Protein conserved in bacteria
IMX20_03355	COG0647	UMP catabolic process
IMX20_03365	COG0492	ferredoxin-NADP+ reductase activity
IMX20_03370	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
IMX20_03375	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IMX20_03380	COG1098	S1 RNA binding domain
IMX20_03385	COG0166	Belongs to the GPI family
IMX20_03520	COG1792	Involved in formation and maintenance of cell shape
IMX20_03530	COG0765	amino acid transport
IMX20_03535	COG1126	abc transporter atp-binding protein
IMX20_03545	COG2868	ribosomal protein
IMX20_03565	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IMX20_03575	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IMX20_03580	COG1263	PTS System
IMX20_03580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX20_03585	COG1737	Transcriptional regulator
IMX20_03610	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IMX20_03620	COG1104	cysteine desulfurase activity
IMX20_03630	COG0482	sulfurtransferase activity
IMX20_03635	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IMX20_03640	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IMX20_03645	COG4472	Bacterial protein of unknown function (DUF965)
IMX20_03650	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IMX20_03655	COG3906	Belongs to the UPF0473 family
IMX20_03665	COG1959	2 iron, 2 sulfur cluster binding
IMX20_03670	COG1511	domain protein
IMX20_03675	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IMX20_03685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IMX20_03700	COG2197	response regulator
IMX20_03705	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IMX20_03710	COG5503	Protein of unknown function (DUF1447)
IMX20_03715	COG4129	membrane
IMX20_03720	COG1272	protein, Hemolysin III
IMX20_03735	COG1307	EDD domain protein, DegV family
IMX20_03755	COG4619	ABC transporter
IMX20_03760	COG0390	transport system, permease component
IMX20_03770	COG1072	(Pantothenic acid kinase))
IMX20_03775	COG0628	permease
IMX20_03780	COG1132	(ABC) transporter
IMX20_03785	COG1132	(ABC) transporter
IMX20_03790	COG0488	(ABC) transporter
IMX20_03795	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IMX20_03800	COG0248	Ppx GppA phosphatase
IMX20_03805	COG0561	phosphatase activity
IMX20_03810	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IMX20_03815	COG3682	Transcriptional regulator
IMX20_03820	COG1780	Probably involved in ribonucleotide reductase function
IMX20_03825	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMX20_03835	COG2267	carboxylic ester hydrolase activity
IMX20_03840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IMX20_03845	COG3331	DNA recombination
IMX20_03850	COG0544	peptidyl-prolyl cis-trans isomerase activity
IMX20_03855	COG1957	nucleoside hydrolase
IMX20_03860	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IMX20_03865	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IMX20_03870	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IMX20_03875	COG0358	DNA primase activity
IMX20_03880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IMX20_03890	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IMX20_03895	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IMX20_03900	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IMX20_03905	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IMX20_03910	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IMX20_03915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IMX20_03920	COG0488	(ABC) transporter
IMX20_03950	COG2384	SAM-dependent methyltransferase
IMX20_03955	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IMX20_03960	COG2195	Cleaves the N-terminal amino acid of tripeptides
IMX20_03965	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
IMX20_03970	COG1074	ATP-dependent DNA helicase activity
IMX20_03980	COG3341	Caulimovirus viroplasmin
IMX20_03980	COG0328	RNA-DNA hybrid ribonuclease activity
IMX20_03985	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IMX20_03990	COG0564	pseudouridine synthase activity
IMX20_03995	COG3763	UPF0154 protein
IMX20_04000	COG1132	(ABC) transporter
IMX20_04005	COG1132	(ABC) transporter
IMX20_04010	COG0204	Acyl-transferase
IMX20_04015	COG0628	permease
IMX20_04025	COG0052	Belongs to the universal ribosomal protein uS2 family
IMX20_04030	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IMX20_04035	COG0528	UMP kinase activity
IMX20_04040	COG0233	cytoplasmic translational termination
IMX20_04045	COG5002	protein histidine kinase activity
IMX20_04050	COG0745	RESPONSE REGULATOR receiver
IMX20_04070	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IMX20_04075	COG4589	Belongs to the CDS family
IMX20_04080	COG0750	zinc metalloprotease
IMX20_04085	COG2176	DNA-directed DNA polymerase activity
IMX20_04100	COG0779	Required for maturation of 30S ribosomal subunits
IMX20_04105	COG0195	Participates in both transcription termination and antitermination
IMX20_04110	COG2740	Nucleic-acid-binding protein implicated in transcription termination
IMX20_04125	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IMX20_04135	COG3759	membrane
IMX20_04145	COG0740	serine-type endopeptidase activity
IMX20_04150	COG2390	Transcriptional regulator
IMX20_04165	COG0149	triose-phosphate isomerase activity
IMX20_04170	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IMX20_04175	COG0148	phosphopyruvate hydratase activity
IMX20_04190	COG4166	transmembrane transport
IMX20_04195	COG4166	transmembrane transport
IMX20_04205	COG0601	transmembrane transport
IMX20_04210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMX20_04215	COG0444	Belongs to the ABC transporter superfamily
IMX20_04220	COG4608	Belongs to the ABC transporter superfamily
IMX20_04235	COG0557	exoribonuclease II activity
IMX20_04240	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IMX20_04250	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
IMX20_04255	COG0588	phosphoglycerate mutase activity
IMX20_04260	COG3949	Membrane
IMX20_04340	COG1715	Restriction endonuclease
IMX20_04405	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IMX20_04415	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IMX20_04425	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IMX20_04430	COG0439	Biotin carboxylase
IMX20_04435	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IMX20_04470	COG0116	Belongs to the methyltransferase superfamily
IMX20_04480	COG3599	regulation of cell shape
IMX20_04495	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IMX20_04500	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IMX20_04505	COG1490	D-aminoacyl-tRNA deacylase activity
IMX20_04515	COG0124	histidyl-tRNA synthetase
IMX20_04520	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IMX20_04535	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IMX20_04545	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IMX20_04550	COG0167	dihydroorotate dehydrogenase activity
IMX20_04555	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IMX20_04560	COG0346	lactoylglutathione lyase activity
IMX20_04565	COG0735	belongs to the Fur family
IMX20_04575	COG1610	YqeY-like protein
IMX20_04580	COG1028	Short-chain dehydrogenase reductase Sdr
IMX20_04595	COG1702	phosphate starvation-inducible protein PhoH
IMX20_04600	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IMX20_04610	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IMX20_04615	COG1381	Involved in DNA repair and RecF pathway recombination
IMX20_04620	COG0752	glycyl-tRNA synthetase alpha subunit
IMX20_04625	COG0751	glycine-tRNA ligase activity
IMX20_04635	COG1234	tRNA 3'-trailer cleavage
IMX20_04640	COG4221	oxidoreductase activity
IMX20_04645	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IMX20_04645	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
IMX20_04650	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IMX20_04660	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IMX20_04675	COG1293	RNA-binding protein homologous to eukaryotic snRNP
IMX20_04685	COG4120	Belongs to the binding-protein-dependent transport system permease family
IMX20_04690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IMX20_04690	COG1116	anion transmembrane transporter activity
IMX20_04700	COG4166	transmembrane transport
IMX20_04705	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IMX20_04710	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IMX20_04715	COG0494	nUDIX hydrolase
IMX20_04720	COG1349	DNA-binding transcription factor activity
IMX20_04725	COG1105	Belongs to the carbohydrate kinase PfkB family
IMX20_04730	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IMX20_04730	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IMX20_04730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMX20_04735	COG1132	(ABC) transporter
IMX20_04740	COG1132	(ABC) transporter
IMX20_04750	COG0456	acetyltransferase
IMX20_04760	COG1126	abc transporter atp-binding protein
IMX20_04770	COG1175	transmembrane transport
IMX20_04775	COG0395	ABC-type sugar transport system, permease component
IMX20_04785	COG3842	ATPase activity
IMX20_04790	COG0366	Alpha amylase catalytic
IMX20_04795	COG1609	Transcriptional regulator
IMX20_04800	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IMX20_04805	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
IMX20_04825	COG2211	Major facilitator Superfamily
IMX20_04840	COG2086	electron transfer activity
IMX20_04845	COG1960	acyl-CoA dehydrogenase activity
IMX20_04865	COG1301	dicarboxylic acid transport
IMX20_04875	COG4974	Belongs to the 'phage' integrase family
IMX20_04885	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IMX20_04890	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IMX20_04900	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IMX20_04905	COG0569	domain protein
IMX20_04910	COG1227	inorganic diphosphatase activity
IMX20_04920	COG0183	Belongs to the thiolase family
IMX20_04925	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMX20_04930	COG0187	DNA topoisomerase II activity
IMX20_04945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IMX20_04950	COG0758	DNA mediated transformation
IMX20_04955	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IMX20_04970	COG3409	Peptidoglycan-binding domain 1 protein
IMX20_04970	COG0793	Belongs to the peptidase S41A family
IMX20_04995	COG0488	(ABC) transporter
IMX20_05005	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMX20_05010	COG0717	Belongs to the dCTP deaminase family
IMX20_05025	COG0656	L-ascorbic acid biosynthetic process
IMX20_05045	COG0484	heat shock protein binding
IMX20_05050	COG0443	Heat shock 70 kDa protein
IMX20_05055	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IMX20_05060	COG1420	regulation of RNA biosynthetic process
IMX20_05065	COG1473	amidohydrolase
IMX20_05070	COG0196	riboflavin kinase activity
IMX20_05075	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IMX20_05085	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IMX20_05090	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IMX20_05100	COG0009	L-threonylcarbamoyladenylate synthase
IMX20_05105	COG2890	protein-(glutamine-N5) methyltransferase activity
IMX20_05110	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IMX20_05115	COG1435	thymidine kinase activity
IMX20_05120	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IMX20_05125	COG3442	glutamine amidotransferase
IMX20_05140	COG1132	(ABC) transporter
IMX20_05145	COG0628	permease
IMX20_05150	COG2706	6-phosphogluconolactonase activity
IMX20_05155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IMX20_05160	COG1079	Belongs to the binding-protein-dependent transport system permease family
IMX20_05165	COG4603	Belongs to the binding-protein-dependent transport system permease family
IMX20_05170	COG3845	ABC transporter
IMX20_05175	COG1744	ABC transporter substrate-binding protein PnrA-like
IMX20_05180	COG2190	(PTS) system
IMX20_05180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX20_05180	COG1263	PTS System
IMX20_05185	COG1968	undecaprenyl-diphosphatase activity
IMX20_05190	COG0527	aspartate kinase activity
IMX20_05195	COG0297	glycogen (starch) synthase activity
IMX20_05200	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IMX20_05205	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IMX20_05220	COG0346	lactoylglutathione lyase activity
IMX20_05240	COG0517	IMP dehydrogenase activity
IMX20_05245	COG0683	leucine binding
IMX20_05250	COG2183	response to ionizing radiation
IMX20_05270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMX20_05290	COG0018	arginyl-trna synthetase
IMX20_05300	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IMX20_05310	COG1136	(ABC) transporter
IMX20_05310	COG0577	efflux transmembrane transporter activity
IMX20_05320	COG0509	glycine decarboxylation via glycine cleavage system
IMX20_05325	COG0772	Belongs to the SEDS family
IMX20_05330	COG1295	ribonuclease BN
IMX20_05345	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IMX20_05350	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IMX20_05355	COG0497	DNA recombination
IMX20_05360	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
IMX20_05370	COG1722	exodeoxyribonuclease VII activity
IMX20_05375	COG1570	exodeoxyribonuclease VII activity
IMX20_05380	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IMX20_05385	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IMX20_05395	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IMX20_05400	COG0006	proline dipeptidase activity
IMX20_05425	COG4537	Required for transformation and DNA binding
IMX20_05430	COG1459	type II secretion system
IMX20_05435	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IMX20_05450	COG1269	ATP hydrolysis coupled proton transport
IMX20_05480	COG1394	ATPase activity, coupled to movement of substances
IMX20_05485	COG0217	transcriptional regulatory protein
IMX20_05490	COG1597	lipid kinase activity
IMX20_05495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IMX20_05500	COG1063	alcohol dehydrogenase
IMX20_05505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IMX20_05510	COG0656	L-ascorbic acid biosynthetic process
IMX20_05520	COG3830	Belongs to the UPF0237 family
IMX20_05525	COG2843	Capsule synthesis protein
IMX20_05545	COG0668	transmembrane transport
IMX20_05550	COG0622	Phosphoesterase
IMX20_05555	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IMX20_05570	COG3118	belongs to the thioredoxin family
IMX20_05575	COG1193	negative regulation of DNA recombination
IMX20_05590	COG0765	amino acid transport
IMX20_05640	COG0179	Fumarylacetoacetate (FAA) hydrolase
IMX20_05645	COG1720	tRNA m6t6A37 methyltransferase activity
IMX20_05655	COG2176	DNA-directed DNA polymerase activity
IMX20_05660	COG1671	Belongs to the UPF0178 family
IMX20_05670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IMX20_05675	COG0765	amino acid transport
IMX20_05680	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IMX20_05690	COG0561	phosphatase activity
IMX20_05705	COG1737	Transcriptional regulator
IMX20_05710	COG0673	inositol 2-dehydrogenase activity
IMX20_05715	COG0673	inositol 2-dehydrogenase activity
IMX20_05720	COG0584	glycerophosphoryl diester phosphodiesterase
IMX20_05735	COG1175	transmembrane transport
IMX20_05755	COG0083	homoserine kinase activity
IMX20_05770	COG1304	FMN binding
IMX20_05780	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IMX20_05785	COG1122	ATPase activity
IMX20_05790	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IMX20_05805	COG0802	atpase or kinase
IMX20_05810	COG0280	phosphate acetyltransferase
IMX20_05815	COG1070	Carbohydrate kinase
IMX20_05820	COG0072	phenylalanine-tRNA ligase activity
IMX20_05825	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IMX20_05830	COG1733	regulation of RNA biosynthetic process
IMX20_05840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMX20_05850	COG1187	pseudouridine synthase activity
IMX20_05855	COG2244	polysaccharide biosynthetic process
IMX20_05865	COG0495	leucyl-tRNA aminoacylation
IMX20_05870	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IMX20_05880	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
IMX20_05885	COG1705	Flagellar rod assembly protein muramidase FlgJ
IMX20_05885	COG1388	LysM domain
IMX20_05890	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
IMX20_05900	COG1278	Cold shock
IMX20_05910	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IMX20_05945	COG2759	Belongs to the formate--tetrahydrofolate ligase family
IMX20_05950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IMX20_05960	COG0525	valine-tRNA ligase activity
IMX20_05965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IMX20_05970	COG1940	carbohydrate kinase activity
IMX20_05975	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IMX20_05980	COG0457	Tetratricopeptide repeat
IMX20_05980	COG0705	Rhomboid family
IMX20_05985	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IMX20_05990	COG0768	penicillin binding
IMX20_06000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IMX20_06010	COG0513	Belongs to the DEAD box helicase family
IMX20_06015	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IMX20_06020	COG1744	ABC transporter substrate-binding protein PnrA-like
IMX20_06025	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IMX20_06030	COG4109	DRTGG domain
IMX20_06050	COG1862	Preprotein translocase
IMX20_06055	COG0343	queuine tRNA-ribosyltransferase activity
IMX20_06070	COG4864	UPF0365 protein
IMX20_06080	COG0542	response to heat
IMX20_06090	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IMX20_06105	COG1733	regulation of RNA biosynthetic process
IMX20_06110	COG1937	Protein conserved in bacteria
IMX20_06115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IMX20_06120	COG0446	pyridine nucleotide-disulphide oxidoreductase
IMX20_06135	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IMX20_06140	COG1132	(ABC) transporter
IMX20_06155	COG0151	Belongs to the GarS family
IMX20_06160	COG0138	bifunctional purine biosynthesis protein purh
IMX20_06165	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IMX20_06170	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IMX20_06175	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IMX20_06180	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IMX20_06185	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMX20_06205	COG0673	inositol 2-dehydrogenase activity
IMX20_06210	COG1012	belongs to the aldehyde dehydrogenase family
IMX20_06215	COG0038	chloride channel
IMX20_06220	COG0335	large ribosomal subunit rRNA binding
IMX20_06240	COG0336	Belongs to the RNA methyltransferase TrmD family
IMX20_06255	COG0514	ATP-dependent DNA helicase (RecQ)
IMX20_06270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IMX20_06280	COG1837	Belongs to the UPF0109 family
IMX20_06290	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IMX20_06295	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IMX20_06300	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IMX20_06310	COG1940	carbohydrate kinase activity
IMX20_06315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IMX20_06320	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IMX20_06325	COG4894	glucomannan catabolic process
IMX20_06330	COG0552	protein localization to endoplasmic reticulum
IMX20_06335	COG0561	phosphatase activity
IMX20_06340	COG1196	nuclear chromosome segregation
IMX20_06345	COG0571	ribonuclease III activity
IMX20_06350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IMX20_06355	COG0416	fatty acid biosynthetic process
IMX20_06360	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IMX20_06365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMX20_06390	COG0708	Exodeoxyribonuclease III
IMX20_06400	COG1012	belongs to the aldehyde dehydrogenase family
IMX20_06400	COG1454	alcohol dehydrogenase
IMX20_06405	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IMX20_06410	COG1882	Formate acetyltransferase
IMX20_06420	COG2151	metal-sulfur cluster biosynthetic enzyme
IMX20_06460	COG1879	ABC-type sugar transport system periplasmic component
IMX20_06475	COG1869	D-ribose catabolic process
IMX20_06480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMX20_06490	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IMX20_06525	COG1091	dTDP-4-dehydrorhamnose reductase activity
IMX20_06535	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IMX20_06540	COG1215	transferase activity, transferring glycosyl groups
IMX20_06560	COG0297	glycogen (starch) synthase activity
IMX20_06565	COG0110	maltose O-acetyltransferase activity
IMX20_06570	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IMX20_06575	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IMX20_06580	COG0489	protein tyrosine kinase activity
IMX20_06615	COG1216	Glycosyl transferase, family 2
IMX20_06630	COG0438	transferase activity, transferring glycosyl groups
IMX20_06635	COG0438	transferase activity, transferring glycosyl groups
IMX20_06640	COG0438	transferase activity, transferring glycosyl groups
IMX20_06650	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IMX20_06655	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IMX20_06660	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IMX20_06665	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IMX20_06670	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IMX20_06685	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IMX20_06700	COG1562	ergosterol biosynthetic process
IMX20_06730	COG1302	Protein conserved in bacteria
IMX20_06735	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IMX20_06740	COG1564	THIamine pyrophosphokinase
IMX20_06745	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IMX20_06750	COG1162	GTPase activity
IMX20_06760	COG0631	protein serine/threonine phosphatase activity
IMX20_06765	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IMX20_06765	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IMX20_06770	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IMX20_06775	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IMX20_06780	COG0402	S-adenosylhomocysteine deaminase activity
IMX20_06785	COG1758	RNA polymerase activity
IMX20_06790	COG0194	GDP metabolic process
IMX20_06800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IMX20_06815	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IMX20_06820	COG1185	polyribonucleotide nucleotidyltransferase activity
IMX20_06825	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IMX20_06830	COG0671	phosphoesterase, PA-phosphatase related
IMX20_06835	COG0556	nucleotide-excision repair
IMX20_06845	COG1466	dna polymerase III delta subunit
IMX20_06855	COG1555	photosystem II stabilization
IMX20_06855	COG1596	polysaccharide export
IMX20_06860	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IMX20_06865	COG0742	ribosomal rna small subunit methyltransferase
IMX20_06885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IMX20_06890	COG0783	Belongs to the Dps family
IMX20_06910	COG4471	UPF0298 protein
IMX20_06915	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IMX20_06920	COG1263	PTS System
IMX20_06920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX20_06920	COG2190	(PTS) system
IMX20_06930	COG0772	Belongs to the SEDS family
IMX20_06935	COG1217	gtp-binding protein TYPA
IMX20_06940	COG0483	inositol monophosphate 1-phosphatase activity
IMX20_06945	COG4476	Belongs to the UPF0223 family
IMX20_06970	COG0673	inositol 2-dehydrogenase activity
IMX20_06980	COG0534	Mate efflux family protein
IMX20_06985	COG3177	Filamentation induced by cAMP protein fic
IMX20_07000	COG0022	dehydrogenase e1 component
IMX20_07010	COG0242	peptide deformylase activity
IMX20_07015	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IMX20_07045	COG3425	synthase
IMX20_07050	COG1904	glucuronate isomerase
IMX20_07060	COG0800	Aldolase
IMX20_07070	COG1028	Short-chain dehydrogenase reductase Sdr
IMX20_07075	COG1312	Catalyzes the dehydration of D-mannonate
IMX20_07085	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IMX20_07095	COG0765	amino acid transport
IMX20_07100	COG0765	amino acid transport
IMX20_07105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMX20_07150	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IMX20_07170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IMX20_07185	COG1054	Belongs to the UPF0176 family
IMX20_07190	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IMX20_07195	COG4120	Belongs to the binding-protein-dependent transport system permease family
IMX20_07210	COG1876	peptidase activity
IMX20_07215	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IMX20_07220	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IMX20_07225	COG0252	asparaginase activity
IMX20_07235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMX20_07245	COG0489	protein tyrosine kinase activity
IMX20_07260	COG4464	protein tyrosine phosphatase activity
IMX20_07265	COG1051	belongs to the nudix hydrolase family
IMX20_07275	COG1307	EDD domain protein, DegV family
IMX20_07305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMX20_07315	COG1316	TRANSCRIPTIONal
IMX20_07320	COG0024	Methionine aminopeptidase
IMX20_07330	COG0716	FMN binding
IMX20_07335	COG2309	aminopeptidase activity
IMX20_07345	COG2246	polysaccharide biosynthetic process
IMX20_07350	COG0463	Glycosyl transferase, family 2
IMX20_07370	COG1215	transferase activity, transferring glycosyl groups
IMX20_07395	COG0438	transferase activity, transferring glycosyl groups
IMX20_07410	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IMX20_07415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IMX20_07420	COG1121	(ABC) transporter
IMX20_07425	COG3443	Belongs to the bacterial solute-binding protein 9 family
IMX20_07425	COG0803	Belongs to the bacterial solute-binding protein 9 family
IMX20_07430	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IMX20_07435	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IMX20_07445	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IMX20_07450	COG4466	Protein conserved in bacteria
IMX20_07455	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IMX20_07465	COG0084	hydrolase, TatD family'
IMX20_07470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMX20_07470	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMX20_07480	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IMX20_07490	COG2249	NAD(P)H dehydrogenase (quinone) activity
IMX20_07495	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IMX20_07520	COG2738	Putative neutral zinc metallopeptidase
IMX20_07540	COG1335	isochorismatase
IMX20_07545	COG0436	Aminotransferase
IMX20_07550	COG1522	sequence-specific DNA binding
IMX20_07565	COG1966	Carbon starvation protein
IMX20_07575	COG1028	Short-chain dehydrogenase reductase Sdr
IMX20_07605	COG4509	Sortase family
IMX20_07635	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IMX20_07640	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IMX20_07645	COG0569	domain protein
IMX20_07650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMX20_07655	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IMX20_07665	COG4853	Protein conserved in bacteria
IMX20_07675	COG5002	protein histidine kinase activity
IMX20_07680	COG0745	RESPONSE REGULATOR receiver
IMX20_07700	COG1472	Belongs to the glycosyl hydrolase 3 family
IMX20_07705	COG1073	alpha beta
IMX20_07710	COG0446	pyridine nucleotide-disulphide oxidoreductase
IMX20_07715	COG0628	permease
IMX20_07740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMX20_07750	COG1028	Short-chain dehydrogenase reductase Sdr
IMX20_07755	COG0475	glutathione-regulated potassium exporter activity
IMX20_07760	COG0588	phosphoglycerate mutase activity
IMX20_07785	COG3527	Alpha-acetolactate decarboxylase
IMX20_07805	COG0531	amino acid
IMX20_07810	COG1621	beta-fructofuranosidase activity
IMX20_07835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IMX20_07840	COG4807	Protein conserved in bacteria
IMX20_07855	COG0753	catalase activity
IMX20_07860	COG1902	pentaerythritol trinitrate reductase activity
IMX20_07875	COG1028	Short-chain dehydrogenase reductase Sdr
IMX20_07880	COG0110	maltose O-acetyltransferase activity
IMX20_07885	COG0583	DNA-binding transcription factor activity
IMX20_07890	COG0564	pseudouridine synthase activity
IMX20_07905	COG2723	6-phospho-beta-galactosidase activity
IMX20_07910	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IMX20_07915	COG2188	Transcriptional regulator
IMX20_07920	COG4720	Psort location CytoplasmicMembrane, score
IMX20_07925	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IMX20_07930	COG1447	Phosphotransferase system cellobiose-specific component IIA
IMX20_07950	COG0159	tryptophan synthase activity
IMX20_07955	COG0133	tryptophan synthase activity
IMX20_07965	COG0134	indole-3-glycerol-phosphate synthase activity
IMX20_07970	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IMX20_07975	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IMX20_07975	COG0512	Glutamine amidotransferase of anthranilate synthase
IMX20_07985	COG4895	conserved protein (DUF2196)
IMX20_07990	COG2873	o-acetylhomoserine
IMX20_07995	COG1959	2 iron, 2 sulfur cluster binding
IMX20_08010	COG2321	neutral zinc metallopeptidase
IMX20_08025	COG0778	Nitroreductase
IMX20_08035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMX20_08050	COG0446	pyridine nucleotide-disulphide oxidoreductase
IMX20_08110	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IMX20_08135	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IMX20_08140	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMX20_08145	COG0154	amidase activity
IMX20_08155	COG4851	CamS sex pheromone cAM373 precursor
IMX20_08160	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IMX20_08165	COG0210	DNA helicase
IMX20_08175	COG1705	Flagellar rod assembly protein muramidase FlgJ
IMX20_08220	COG0737	Belongs to the 5'-nucleotidase family
IMX20_08240	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IMX20_08250	COG5002	protein histidine kinase activity
IMX20_08250	COG3850	Histidine kinase
IMX20_08255	COG0745	RESPONSE REGULATOR receiver
IMX20_08260	COG0629	single-stranded DNA binding
IMX20_08270	COG1481	regulation of sporulation
IMX20_08275	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IMX20_08280	COG1660	Displays ATPase and GTPase activities
IMX20_08285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMX20_08290	COG0492	ferredoxin-NADP+ reductase activity
IMX20_08295	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IMX20_08300	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IMX20_08320	COG1983	PspC domain protein
IMX20_08335	COG0419	ATPase involved in DNA repair
IMX20_08340	COG0420	3'-5' exonuclease activity
IMX20_08345	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IMX20_08350	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IMX20_08355	COG0581	inorganic phosphate transmembrane transporter activity
IMX20_08360	COG0573	inorganic phosphate transmembrane transporter activity
IMX20_08365	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IMX20_08370	COG5002	protein histidine kinase activity
IMX20_08375	COG0745	RESPONSE REGULATOR receiver
IMX20_08385	COG0653	protein targeting
IMX20_08400	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IMX20_08405	COG1307	EDD domain protein, DegV family
IMX20_08410	COG1739	Uncharacterized protein family UPF0029
IMX20_08415	COG0277	FAD linked oxidase domain protein
IMX20_08435	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IMX20_08440	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IMX20_08450	COG0765	amino acid transport
IMX20_08455	COG0431	NADPH-dependent FMN reductase
IMX20_08465	COG0765	amino acid transport
IMX20_08470	COG0165	Argininosuccinate lyase
IMX20_08480	COG0459	protein refolding
IMX20_08485	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IMX20_08495	COG0488	(ABC) transporter
IMX20_08510	COG0183	Belongs to the thiolase family
IMX20_08515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IMX20_08535	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IMX20_08545	COG0494	nUDIX hydrolase
IMX20_08565	COG1394	ATPase activity, coupled to movement of substances
IMX20_08570	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
IMX20_08575	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
IMX20_08580	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
IMX20_08585	COG1527	subunit (C
IMX20_08595	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IMX20_08600	COG1269	ATP hydrolysis coupled proton transport
IMX20_08610	COG0590	tRNA wobble adenosine to inosine editing
IMX20_08615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX20_08615	COG1263	PTS System
IMX20_08620	COG0366	Alpha amylase catalytic
IMX20_08625	COG2188	Transcriptional regulator
IMX20_08645	COG0542	response to heat
IMX20_08655	COG0473	3-isopropylmalate dehydrogenase activity
IMX20_08660	COG2851	Citrate transporter
IMX20_08700	COG1131	(ABC) transporter
IMX20_08715	COG1940	carbohydrate kinase activity
IMX20_08725	COG0058	SHG alpha-glucan phosphorylase activity
IMX20_08730	COG1640	4-alpha-glucanotransferase
IMX20_08735	COG1609	Transcriptional regulator
IMX20_08750	COG0673	inositol 2-dehydrogenase activity
IMX20_08765	COG0673	inositol 2-dehydrogenase activity
IMX20_08770	COG3842	ATPase activity
IMX20_08780	COG3833	ABC-type maltose transport systems, permease component
IMX20_08785	COG1175	transmembrane transport
IMX20_08790	COG2182	Extracellular solute-binding protein
IMX20_08800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX20_08800	COG2190	(PTS) system
IMX20_08800	COG1263	PTS System
IMX20_08815	COG1737	Transcriptional regulator
IMX20_08820	COG1486	melibiose metabolic process
IMX20_08825	COG1263	PTS System
IMX20_08825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX20_08830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IMX20_08860	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IMX20_08865	COG0456	acetyltransferase
IMX20_08870	COG0456	acetyltransferase
IMX20_08875	COG1214	PFAM Peptidase M22, glycoprotease
IMX20_08880	COG2211	Major facilitator Superfamily
IMX20_08885	COG0346	lactoylglutathione lyase activity
IMX20_08890	COG0400	carboxylic ester hydrolase activity
IMX20_08895	COG4224	UPF0291 protein
IMX20_08905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX20_08905	COG2190	(PTS) system
IMX20_08905	COG1263	PTS System
IMX20_08915	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IMX20_08925	COG0440	acetolactate synthase activity
IMX20_08930	COG0028	Belongs to the TPP enzyme family
IMX20_08935	COG1119	ATPase activity
IMX20_08945	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IMX20_08965	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IMX20_08975	COG0561	phosphatase activity
IMX20_08980	COG0366	Alpha amylase catalytic
IMX20_08985	COG2252	PERMEase
IMX20_08990	COG1304	FMN binding
IMX20_09000	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IMX20_09010	COG2226	methyltransferase
IMX20_09025	COG1028	Short-chain dehydrogenase reductase Sdr
IMX20_09035	COG1464	Belongs to the NlpA lipoprotein family
IMX20_09040	COG0436	Aminotransferase
IMX20_09055	COG0363	glucosamine-6-phosphate deaminase activity
IMX20_09060	COG1028	Short-chain dehydrogenase reductase Sdr
IMX20_09065	COG2323	membrane
IMX20_09070	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IMX20_09075	COG1388	LysM domain
IMX20_09090	COG1187	pseudouridine synthase activity
IMX20_09100	COG4856	YbbR-like protein
IMX20_09105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMX20_09110	COG0789	Transcriptional regulator
IMX20_09115	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IMX20_09125	COG1302	Protein conserved in bacteria
IMX20_09145	COG1486	melibiose metabolic process
IMX20_09165	COG0626	cystathionine gamma-synthase activity
IMX20_09170	COG2514	catechol 2,3-dioxygenase activity
IMX20_09180	COG0039	L-malate dehydrogenase activity
IMX20_09185	COG0589	response to stress
IMX20_09195	COG1363	Peptidase, m42
IMX20_09295	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IMX20_09300	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IMX20_09315	COG0745	RESPONSE REGULATOR receiver
IMX20_09320	COG0517	IMP dehydrogenase activity
IMX20_09320	COG0516	GMP reductase activity
IMX20_09340	COG0012	GTP binding
IMX20_09345	COG4481	Protein conserved in bacteria
IMX20_09350	COG1475	DNA binding
IMX20_09355	COG1192	Involved in chromosome partitioning
IMX20_09360	COG0357	Ribosomal RNA small subunit methyltransferase G
IMX20_09370	COG0445	tRNA wobble uridine modification
IMX20_09375	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IMX20_09385	COG0668	transmembrane transport
IMX20_09390	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMX20_09395	COG3711	transcriptional antiterminator
IMX20_09400	COG2213	PTS system mannitol-specific
IMX20_09405	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IMX20_09410	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IMX20_09415	COG1847	R3H domain protein
IMX20_09420	COG0706	membrane insertase activity
IMX20_09460	COG1192	Involved in chromosome partitioning
IMX20_09470	COG2124	cytochrome p450
IMX20_09495	COG0454	-acetyltransferase
IMX20_09525	COG0783	Belongs to the Dps family
IMX20_09530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IMX20_09535	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IMX20_09540	COG2217	Heavy metal translocating P-type atpase
IMX20_09555	COG2217	Heavy metal translocating P-type atpase
IMX20_09615	COG0390	transport system, permease component
IMX20_09620	COG4619	ABC transporter
IMX20_09635	COG1388	LysM domain
IMX20_09645	COG3682	Transcriptional regulator
IMX20_09650	COG2217	Heavy metal translocating P-type atpase
IMX20_09665	COG2217	Heavy metal translocating P-type atpase
IMX20_09685	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IMX20_09730	COG2814	Major facilitator Superfamily