locus-tag	class	description
FOB80_00015	COG0494	nUDIX hydrolase
FOB80_00020	COG0513	Belongs to the DEAD box helicase family
FOB80_00035	COG1394	ATPase activity, coupled to movement of substances
FOB80_00040	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
FOB80_00045	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
FOB80_00050	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
FOB80_00055	COG1527	subunit (C
FOB80_00060	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
FOB80_00065	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOB80_00070	COG1269	ATP hydrolysis coupled proton transport
FOB80_00080	COG0590	tRNA wobble adenosine to inosine editing
FOB80_00085	COG1263	PTS System
FOB80_00085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB80_00090	COG0366	Alpha amylase catalytic
FOB80_00105	COG2188	Transcriptional regulator
FOB80_00125	COG0542	response to heat
FOB80_00135	COG0473	3-isopropylmalate dehydrogenase activity
FOB80_00140	COG2851	Citrate transporter
FOB80_00180	COG1131	(ABC) transporter
FOB80_00195	COG1940	carbohydrate kinase activity
FOB80_00200	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOB80_00205	COG0058	SHG alpha-glucan phosphorylase activity
FOB80_00210	COG1640	4-alpha-glucanotransferase
FOB80_00215	COG1609	Transcriptional regulator
FOB80_00230	COG0673	inositol 2-dehydrogenase activity
FOB80_00245	COG0673	inositol 2-dehydrogenase activity
FOB80_00250	COG3842	ATPase activity
FOB80_00260	COG3833	ABC-type maltose transport systems, permease component
FOB80_00265	COG1175	transmembrane transport
FOB80_00270	COG2182	Extracellular solute-binding protein
FOB80_00280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB80_00280	COG2190	(PTS) system
FOB80_00280	COG1263	PTS System
FOB80_00295	COG1737	Transcriptional regulator
FOB80_00300	COG1486	melibiose metabolic process
FOB80_00305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB80_00305	COG1263	PTS System
FOB80_00310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOB80_00325	COG1309	transcriptional regulator
FOB80_00345	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOB80_00350	COG0456	acetyltransferase
FOB80_00360	COG1214	PFAM Peptidase M22, glycoprotease
FOB80_00365	COG2211	Major facilitator Superfamily
FOB80_00370	COG0346	lactoylglutathione lyase activity
FOB80_00375	COG0400	carboxylic ester hydrolase activity
FOB80_00380	COG4224	UPF0291 protein
FOB80_00390	COG1609	Transcriptional regulator
FOB80_00395	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOB80_00400	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOB80_00410	COG2723	6-phospho-beta-galactosidase activity
FOB80_00435	COG2723	6-phospho-beta-galactosidase activity
FOB80_00440	COG1263	PTS System
FOB80_00440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB80_00440	COG2190	(PTS) system
FOB80_00450	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOB80_00455	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOB80_00460	COG0440	acetolactate synthase activity
FOB80_00465	COG0028	Belongs to the TPP enzyme family
FOB80_00470	COG1119	ATPase activity
FOB80_00480	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOB80_00500	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOB80_00510	COG0561	phosphatase activity
FOB80_00515	COG0366	Alpha amylase catalytic
FOB80_00520	COG2252	PERMEase
FOB80_00525	COG1304	FMN binding
FOB80_00530	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOB80_00540	COG2226	methyltransferase
FOB80_00555	COG1028	Short-chain dehydrogenase reductase Sdr
FOB80_00600	COG3316	Transposase and inactivated derivatives
FOB80_00640	COG1764	response to oxidative stress
FOB80_00655	COG1464	Belongs to the NlpA lipoprotein family
FOB80_00660	COG0436	Aminotransferase
FOB80_00665	COG0246	Mannitol dehydrogenase
FOB80_00670	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB80_00675	COG3711	transcriptional antiterminator
FOB80_00680	COG2213	PTS system mannitol-specific
FOB80_00685	COG0363	glucosamine-6-phosphate deaminase activity
FOB80_00690	COG1028	Short-chain dehydrogenase reductase Sdr
FOB80_00710	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FOB80_00715	COG0732	type I restriction modification DNA specificity domain
FOB80_00720	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FOB80_00750	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOB80_00770	COG1187	pseudouridine synthase activity
FOB80_00780	COG4856	YbbR-like protein
FOB80_00785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOB80_00795	COG1695	Transcriptional regulator
FOB80_00800	COG0789	Transcriptional regulator
FOB80_00805	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FOB80_00815	COG1302	Protein conserved in bacteria
FOB80_00835	COG1486	melibiose metabolic process
FOB80_00840	COG1737	Transcriptional regulator
FOB80_00850	COG0583	DNA-binding transcription factor activity
FOB80_00855	COG0626	cystathionine gamma-synthase activity
FOB80_00860	COG2514	catechol 2,3-dioxygenase activity
FOB80_00870	COG0039	L-malate dehydrogenase activity
FOB80_00875	COG0589	response to stress
FOB80_00885	COG1363	Peptidase, m42
FOB80_00980	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOB80_00985	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FOB80_01000	COG0745	RESPONSE REGULATOR receiver
FOB80_01025	COG0012	GTP binding
FOB80_01030	COG4481	Protein conserved in bacteria
FOB80_01035	COG1475	DNA binding
FOB80_01040	COG1192	Involved in chromosome partitioning
FOB80_01045	COG0357	Ribosomal RNA small subunit methyltransferase G
FOB80_01055	COG0445	tRNA wobble uridine modification
FOB80_01060	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOB80_01070	COG0668	transmembrane transport
FOB80_01075	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB80_01080	COG3711	transcriptional antiterminator
FOB80_01085	COG2213	PTS system mannitol-specific
FOB80_01090	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FOB80_01095	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FOB80_01100	COG1847	R3H domain protein
FOB80_01105	COG0706	membrane insertase activity
FOB80_01125	COG0592	DNA-directed DNA polymerase activity
FOB80_01130	COG2501	S4 domain
FOB80_01135	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FOB80_01140	COG0187	DNA topoisomerase II activity
FOB80_01145	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOB80_01150	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOB80_01155	COG4166	transmembrane transport
FOB80_01160	COG0360	Binds together with S18 to 16S ribosomal RNA
FOB80_01165	COG0629	single-stranded DNA binding
FOB80_01170	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FOB80_01175	COG0346	lactoylglutathione lyase activity
FOB80_01180	COG0371	Dehydrogenase
FOB80_01185	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOB80_01195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB80_01200	COG0601	transmembrane transport
FOB80_01205	COG4608	Belongs to the ABC transporter superfamily
FOB80_01220	COG0359	binds to the 23S rRNA
FOB80_01225	COG0305	Participates in initiation and elongation during chromosome replication
FOB80_01230	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FOB80_01240	COG2217	Heavy metal translocating P-type atpase
FOB80_01255	COG1122	ATPase activity
FOB80_01265	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOB80_01275	COG0693	protein deglycase activity
FOB80_01280	COG1428	Deoxynucleoside kinase
FOB80_01295	COG0596	Alpha beta hydrolase
FOB80_01310	COG1346	cytolysis
FOB80_01315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOB80_01325	COG1418	mRNA catabolic process
FOB80_01330	COG1428	Deoxynucleoside kinase
FOB80_01335	COG0602	queuosine metabolic process
FOB80_01340	COG1328	CTP reductase activity
FOB80_01355	COG2151	metal-sulfur cluster biosynthetic enzyme
FOB80_01360	COG2217	Heavy metal translocating P-type atpase
FOB80_01365	COG1461	Dihydroxyacetone kinase
FOB80_01370	COG2376	Dihydroxyacetone kinase
FOB80_01375	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FOB80_01380	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOB80_01385	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOB80_01390	COG0789	Transcriptional regulator
FOB80_01410	COG3715	PTS system
FOB80_01415	COG3716	PTS system mannose fructose sorbose family IID component
FOB80_01425	COG1482	cell wall glycoprotein biosynthetic process
FOB80_01430	COG2116	formate transmembrane transporter activity
FOB80_01465	COG0756	dUTP diphosphatase activity
FOB80_01470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FOB80_01475	COG4956	integral membrane protein (PIN domain superfamily)
FOB80_01480	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOB80_01495	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOB80_01505	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOB80_01510	COG2233	PERMEase
FOB80_01520	COG1174	glycine betaine transport
FOB80_01525	COG1125	glycine betaine transport
FOB80_01525	COG0517	IMP dehydrogenase activity
FOB80_01530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOB80_01550	COG1464	Belongs to the NlpA lipoprotein family
FOB80_01560	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FOB80_01565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOB80_01595	COG2003	Belongs to the UPF0758 family
FOB80_01630	COG1388	LysM domain
FOB80_01640	COG3682	Transcriptional regulator
FOB80_01645	COG2217	Heavy metal translocating P-type atpase
FOB80_01650	COG2217	Heavy metal translocating P-type atpase
FOB80_01655	COG2217	Heavy metal translocating P-type atpase
FOB80_01675	COG3316	Transposase and inactivated derivatives
FOB80_01700	COG4335	DNA alkylation repair
FOB80_01705	COG1309	transcriptional regulator
FOB80_01735	COG3316	Transposase and inactivated derivatives
FOB80_01765	COG2826	transposase and inactivated derivatives, IS30 family
FOB80_01800	COG3316	Transposase and inactivated derivatives
FOB80_01825	COG2610	gluconate transmembrane transporter activity
FOB80_01830	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOB80_01840	COG0250	Participates in transcription elongation, termination and antitermination
FOB80_01850	COG0704	Plays a role in the regulation of phosphate uptake
FOB80_01855	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOB80_01860	COG0081	regulation of translation
FOB80_01865	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FOB80_01870	COG0222	ribosome binding
FOB80_01880	COG2826	transposase and inactivated derivatives, IS30 family
FOB80_01895	COG0765	amino acid transport
FOB80_01900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB80_01910	COG1121	(ABC) transporter
FOB80_01915	COG1321	iron dependent repressor
FOB80_01915	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOB80_01920	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOB80_01925	COG2813	Specifically methylates the guanine in position
FOB80_01930	COG4175	Glycine betaine
FOB80_01930	COG0517	IMP dehydrogenase activity
FOB80_01950	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOB80_01960	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FOB80_01995	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FOB80_02000	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOB80_02005	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FOB80_02010	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FOB80_02020	COG0470	DNA polymerase III
FOB80_02025	COG1396	sequence-specific DNA binding
FOB80_02030	COG1131	(ABC) transporter
FOB80_02055	COG1122	ATPase activity
FOB80_02075	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FOB80_02075	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FOB80_02085	COG4467	Involved in initiation control of chromosome replication
FOB80_02090	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOB80_02095	COG2827	Endonuclease containing a URI domain
FOB80_02100	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOB80_02110	COG1970	mechanosensitive ion channel activity
FOB80_02115	COG2079	MmgE PrpD family protein
FOB80_02125	COG0372	Belongs to the citrate synthase family
FOB80_02130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOB80_02140	COG1132	(ABC) transporter
FOB80_02145	COG0436	Aminotransferase
FOB80_02150	COG2814	Major facilitator Superfamily
FOB80_02155	COG1078	dGTPase activity
FOB80_02160	COG0095	Lipoate-protein ligase
FOB80_02170	COG3343	RNA polymerase activity
FOB80_02175	COG0504	CTP synthase activity
FOB80_02180	COG1854	S-ribosylhomocysteine lyase activity
FOB80_02195	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOB80_02200	COG0284	orotidine-5'-phosphate decarboxylase activity
FOB80_02210	COG2814	Major facilitator Superfamily
FOB80_02215	COG2832	Protein of unknown function (DUF454)
FOB80_02240	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOB80_02245	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FOB80_02250	COG0254	rRNA binding
FOB80_02260	COG0251	oxidation-reduction process
FOB80_02265	COG0456	acetyltransferase
FOB80_02270	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOB80_02280	COG3764	Sortase (surface protein transpeptidase)
FOB80_02295	COG1181	Belongs to the D-alanine--D-alanine ligase family
FOB80_02300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOB80_02320	COG1174	glycine betaine transport
FOB80_02335	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
FOB80_02340	COG4708	membrane
FOB80_02345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOB80_02360	COG1253	flavin adenine dinucleotide binding
FOB80_02415	COG2326	polyphosphate kinase activity
FOB80_02420	COG0288	reversible hydration of carbon dioxide
FOB80_02425	COG4290	ribonuclease
FOB80_02430	COG2732	(Barnase) inhibitor
FOB80_02465	COG0322	excinuclease ABC activity
FOB80_02470	COG1408	metallophosphoesterase
FOB80_02475	COG0513	Belongs to the DEAD box helicase family
FOB80_02485	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOB80_02495	COG0039	L-malate dehydrogenase activity
FOB80_02500	COG0193	aminoacyl-tRNA hydrolase activity
FOB80_02505	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOB80_02510	COG2244	polysaccharide biosynthetic process
FOB80_02515	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOB80_02525	COG1098	S1 RNA binding domain
FOB80_02530	COG0037	tRNA processing
FOB80_02540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOB80_02545	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FOB80_02555	COG0640	Transcriptional regulator
FOB80_02560	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FOB80_02565	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FOB80_02570	COG0049	tRNA binding
FOB80_02575	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FOB80_02580	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FOB80_02595	COG0505	Belongs to the CarA family
FOB80_02600	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOB80_02610	COG1122	ATPase activity
FOB80_02630	COG0051	transcription antitermination factor activity, RNA binding
FOB80_02635	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FOB80_02640	COG0088	Forms part of the polypeptide exit tunnel
FOB80_02645	COG0089	rRNA binding
FOB80_02650	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FOB80_02660	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FOB80_02665	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FOB80_02670	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FOB80_02675	COG0255	Belongs to the universal ribosomal protein uL29 family
FOB80_02680	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FOB80_02685	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FOB80_02690	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FOB80_02700	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FOB80_02705	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FOB80_02710	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOB80_02715	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FOB80_02720	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FOB80_02725	COG1841	ribosomal large subunit assembly
FOB80_02740	COG0563	adenylate kinase activity
FOB80_02755	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOB80_02760	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FOB80_02765	COG0202	RNA polymerase activity
FOB80_02770	COG0203	ribosomal protein L17
FOB80_02775	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FOB80_02775	COG2755	lipolytic protein G-D-S-L family
FOB80_02785	COG1122	ATPase activity
FOB80_02790	COG1122	ATPase activity
FOB80_02810	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FOB80_02830	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOB80_02840	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOB80_02845	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOB80_02850	COG0583	DNA-binding transcription factor activity
FOB80_02855	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOB80_02860	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FOB80_02880	COG2826	transposase and inactivated derivatives, IS30 family
FOB80_02895	COG2723	6-phospho-beta-galactosidase activity
FOB80_02915	COG0662	Cupin 2, conserved barrel domain protein
FOB80_02920	COG1942	4-Oxalocrotonate Tautomerase
FOB80_02945	COG1518	maintenance of DNA repeat elements
FOB80_02950	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FOB80_02990	COG0577	efflux transmembrane transporter activity
FOB80_03000	COG1309	transcriptional regulator
FOB80_03020	COG2723	6-phospho-beta-galactosidase activity
FOB80_03035	COG3339	Conserved Protein
FOB80_03050	COG0352	thiamine-phosphate diphosphorylase activity
FOB80_03055	COG0351	phosphomethylpyrimidine kinase
FOB80_03065	COG2610	gluconate transmembrane transporter activity
FOB80_03070	COG1929	Belongs to the glycerate kinase type-1 family
FOB80_03075	COG3835	regulator
FOB80_03115	COG1725	Transcriptional regulator
FOB80_03120	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FOB80_03125	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FOB80_03130	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOB80_03135	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOB80_03140	COG0131	Imidazoleglycerol-phosphate dehydratase
FOB80_03145	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FOB80_03150	COG0107	imidazoleglycerol-phosphate synthase activity
FOB80_03155	COG0140	phosphoribosyl-ATP diphosphatase activity
FOB80_03155	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FOB80_03160	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FOB80_03175	COG2188	Transcriptional regulator
FOB80_03180	COG0386	Belongs to the glutathione peroxidase family
FOB80_03185	COG3443	Belongs to the bacterial solute-binding protein 9 family
FOB80_03185	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOB80_03205	COG0656	L-ascorbic acid biosynthetic process
FOB80_03225	COG0702	epimerase
FOB80_03230	COG4708	membrane
FOB80_03245	COG2217	Heavy metal translocating P-type atpase
FOB80_03255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB80_03265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB80_03270	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOB80_03275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB80_03280	COG1126	abc transporter atp-binding protein
FOB80_03285	COG0765	amino acid transport
FOB80_03290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB80_03295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB80_03300	COG4565	transcriptional regulatory protein
FOB80_03305	COG3290	protein histidine kinase activity
FOB80_03310	COG3493	citrate carrier protein
FOB80_03320	COG4166	transmembrane transport
FOB80_03330	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOB80_03355	COG2137	regulation of response to DNA damage stimulus
FOB80_03360	COG1194	a g-specific adenine glycosylase
FOB80_03365	COG3557	Belongs to the UPF0374 family
FOB80_03375	COG1523	belongs to the glycosyl hydrolase 13 family
FOB80_03380	COG4129	membrane
FOB80_03385	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOB80_03395	COG0667	Aldo Keto reductase
FOB80_03505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB80_03510	COG1464	Belongs to the NlpA lipoprotein family
FOB80_03515	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOB80_03520	COG0406	alpha-ribazole phosphatase activity
FOB80_03525	COG2723	6-phospho-beta-galactosidase activity
FOB80_03530	COG2188	Transcriptional regulator
FOB80_03535	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOB80_03550	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOB80_03555	COG0667	Aldo Keto reductase
FOB80_03560	COG0561	phosphatase activity
FOB80_03565	COG3711	transcriptional antiterminator
FOB80_03570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB80_03575	COG2190	(PTS) system
FOB80_03575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB80_03575	COG1263	PTS System
FOB80_03580	COG2723	6-phospho-beta-galactosidase activity
FOB80_03600	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOB80_03605	COG2011	ABC-type metal ion transport system permease component
FOB80_03610	COG1464	Belongs to the NlpA lipoprotein family
FOB80_03615	COG0431	NADPH-dependent FMN reductase
FOB80_03620	COG0454	-acetyltransferase
FOB80_03625	COG0765	amino acid transport
FOB80_03630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB80_03635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB80_03640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB80_03650	COG1126	abc transporter atp-binding protein
FOB80_03655	COG0686	Belongs to the AlaDH PNT family
FOB80_03660	COG3949	Membrane
FOB80_03665	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOB80_03675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOB80_03680	COG3679	Belongs to the UPF0342 family
FOB80_03685	COG0420	3'-5' exonuclease activity
FOB80_03690	COG4717	serine-type aminopeptidase activity
FOB80_03695	COG3481	metal-dependent phosphohydrolase, HD sub domain
FOB80_03705	COG0737	Belongs to the 5'-nucleotidase family
FOB80_03710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOB80_03720	COG0537	adenosine 5'-monophosphoramidase activity
FOB80_03725	COG1131	(ABC) transporter
FOB80_03730	COG4473	ABC transporter
FOB80_03740	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FOB80_03750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB80_03760	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOB80_03775	COG1785	Belongs to the alkaline phosphatase family
FOB80_03800	COG1573	uracil-dna glycosylase
FOB80_03805	COG2270	Major facilitator Superfamily
FOB80_03810	COG0435	Glutathione S-transferase
FOB80_03820	COG0302	gtp cyclohydrolase
FOB80_03825	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOB80_03830	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOB80_03835	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOB80_03840	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOB80_03845	COG0406	alpha-ribazole phosphatase activity
FOB80_03850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOB80_03860	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOB80_03860	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOB80_03865	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOB80_03870	COG0237	dephospho-CoA kinase activity
FOB80_03885	COG1484	DNA-dependent DNA replication
FOB80_03900	COG1302	Protein conserved in bacteria
FOB80_03905	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOB80_03915	COG2818	Glycosylase
FOB80_03930	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOB80_03940	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FOB80_03945	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOB80_03950	COG2011	ABC-type metal ion transport system permease component
FOB80_03955	COG1464	Belongs to the NlpA lipoprotein family
FOB80_03960	COG1464	Belongs to the NlpA lipoprotein family
FOB80_03970	COG0095	Lipoate-protein ligase
FOB80_03975	COG4862	establishment of competence for transformation
FOB80_03980	COG1393	Belongs to the ArsC family
FOB80_03985	COG0180	Tryptophanyl-tRNA synthetase
FOB80_04005	COG4116	CYTH
FOB80_04010	COG2357	RelA SpoT domain protein
FOB80_04020	COG0564	pseudouridine synthase activity
FOB80_04025	COG2239	Acts as a magnesium transporter
FOB80_04035	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOB80_04040	COG0105	UTP biosynthetic process
FOB80_04045	COG0625	glutathione transferase activity
FOB80_04055	COG2153	protein acetylation
FOB80_04060	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FOB80_04065	COG0583	DNA-binding transcription factor activity
FOB80_04075	COG0542	response to heat
FOB80_04080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB80_04090	COG0438	transferase activity, transferring glycosyl groups
FOB80_04095	COG4703	Protein of unknown function (DUF1797)
FOB80_04100	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOB80_04105	COG0460	homoserine dehydrogenase
FOB80_04110	COG0083	homoserine kinase activity
FOB80_04115	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FOB80_04120	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOB80_04125	COG1534	Rna-binding protein
FOB80_04130	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FOB80_04135	COG1713	HD superfamily hydrolase involved in NAD metabolism
FOB80_04140	COG0799	negative regulation of ribosome biogenesis
FOB80_04145	COG2226	methyltransferase
FOB80_04150	COG1323	Belongs to the UPF0348 family
FOB80_04155	COG1399	metal-binding, possibly nucleic acid-binding protein
FOB80_04160	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FOB80_04170	COG2001	Belongs to the MraZ family
FOB80_04190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOB80_04195	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FOB80_04200	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOB80_04205	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOB80_04210	COG0849	cell division
FOB80_04220	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOB80_04235	COG2302	S4 RNA-binding domain
FOB80_04240	COG3599	regulation of cell shape
FOB80_04245	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOB80_04255	COG2261	transglycosylase associated protein
FOB80_04260	COG3853	Toxic anion resistance protein (TelA)
FOB80_04270	COG0494	nUDIX hydrolase
FOB80_04280	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOB80_04285	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FOB80_04290	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FOB80_04300	COG1104	cysteine desulfurase activity
FOB80_04305	COG0301	tRNA thio-modification
FOB80_04310	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOB80_04320	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOB80_04325	COG0745	RESPONSE REGULATOR receiver
FOB80_04340	COG0028	Belongs to the TPP enzyme family
FOB80_04345	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOB80_04350	COG0706	membrane insertase activity
FOB80_04355	COG1254	Belongs to the acylphosphatase family
FOB80_04365	COG1280	lysine exporter protein (LysE YggA)
FOB80_04365	COG1674	ftsk spoiiie
FOB80_04370	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOB80_04380	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FOB80_04420	COG1914	H( )-stimulated, divalent metal cation uptake system
FOB80_04425	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FOB80_04430	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FOB80_04445	COG2255	four-way junction helicase activity
FOB80_04450	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FOB80_04455	COG0587	DNA-directed DNA polymerase activity
FOB80_04460	COG0205	6-phosphofructokinase activity
FOB80_04470	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FOB80_04480	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOB80_04485	COG2996	Protein conserved in bacteria
FOB80_04495	COG4152	abc transporter atp-binding protein
FOB80_04500	COG1668	transmembrane transport
FOB80_04505	COG0456	acetyltransferase
FOB80_04510	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FOB80_04515	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FOB80_04520	COG1187	pseudouridine synthase activity
FOB80_04525	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FOB80_04535	COG0514	ATP-dependent DNA helicase (RecQ)
FOB80_04550	COG0539	negative regulation of cytoplasmic translation
FOB80_04555	COG1160	GTP binding
FOB80_04570	COG1621	beta-fructofuranosidase activity
FOB80_04575	COG1609	Transcriptional regulator
FOB80_04590	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FOB80_04595	COG0617	tRNA 3'-terminal CCA addition
FOB80_04620	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOB80_04625	COG1846	Transcriptional regulator
FOB80_04630	COG0737	Belongs to the 5'-nucleotidase family
FOB80_04635	COG4470	Protein conserved in bacteria
FOB80_04640	COG0647	UMP catabolic process
FOB80_04650	COG0492	ferredoxin-NADP+ reductase activity
FOB80_04655	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FOB80_04660	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOB80_04665	COG1098	S1 RNA binding domain
FOB80_04670	COG0166	Belongs to the GPI family
FOB80_04805	COG1792	Involved in formation and maintenance of cell shape
FOB80_04815	COG0765	amino acid transport
FOB80_04820	COG1126	abc transporter atp-binding protein
FOB80_04830	COG2868	ribosomal protein
FOB80_04845	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOB80_04855	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FOB80_04860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB80_04860	COG1263	PTS System
FOB80_04865	COG1737	Transcriptional regulator
FOB80_04880	COG0589	response to stress
FOB80_04890	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOB80_04895	COG1181	Belongs to the D-alanine--D-alanine ligase family
FOB80_04895	COG2918	glutathione biosynthetic process
FOB80_04900	COG1104	cysteine desulfurase activity
FOB80_04910	COG0482	sulfurtransferase activity
FOB80_04915	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOB80_04920	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOB80_04930	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FOB80_04935	COG3906	Belongs to the UPF0473 family
FOB80_04940	COG1959	2 iron, 2 sulfur cluster binding
FOB80_04945	COG1511	domain protein
FOB80_04950	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOB80_04960	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOB80_04975	COG2197	response regulator
FOB80_04980	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOB80_04990	COG4129	membrane
FOB80_04995	COG1272	protein, Hemolysin III
FOB80_05010	COG1307	EDD domain protein, DegV family
FOB80_05030	COG4619	ABC transporter
FOB80_05035	COG0390	transport system, permease component
FOB80_05045	COG1072	(Pantothenic acid kinase))
FOB80_05050	COG0628	permease
FOB80_05055	COG1132	(ABC) transporter
FOB80_05060	COG1132	(ABC) transporter
FOB80_05065	COG0488	(ABC) transporter
FOB80_05070	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOB80_05080	COG0561	phosphatase activity
FOB80_05085	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FOB80_05090	COG3682	Transcriptional regulator
FOB80_05095	COG1780	Probably involved in ribonucleotide reductase function
FOB80_05100	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOB80_05110	COG2267	carboxylic ester hydrolase activity
FOB80_05115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOB80_05120	COG3331	DNA recombination
FOB80_05125	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOB80_05135	COG1957	nucleoside hydrolase
FOB80_05140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOB80_05145	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FOB80_05150	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FOB80_05155	COG0358	DNA primase activity
FOB80_05160	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOB80_05175	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOB80_05180	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOB80_05185	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FOB80_05190	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FOB80_05195	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FOB80_05200	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOB80_05205	COG0488	(ABC) transporter
FOB80_05215	COG2384	SAM-dependent methyltransferase
FOB80_05220	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOB80_05225	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOB80_05230	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FOB80_05235	COG1074	ATP-dependent DNA helicase activity
FOB80_05245	COG0328	RNA-DNA hybrid ribonuclease activity
FOB80_05245	COG3341	Caulimovirus viroplasmin
FOB80_05250	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FOB80_05255	COG0564	pseudouridine synthase activity
FOB80_05260	COG3763	UPF0154 protein
FOB80_05265	COG1132	(ABC) transporter
FOB80_05270	COG1132	(ABC) transporter
FOB80_05275	COG0204	Acyl-transferase
FOB80_05280	COG0628	permease
FOB80_05290	COG0052	Belongs to the universal ribosomal protein uS2 family
FOB80_05295	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FOB80_05300	COG0528	UMP kinase activity
FOB80_05305	COG0233	cytoplasmic translational termination
FOB80_05310	COG5002	protein histidine kinase activity
FOB80_05315	COG0745	RESPONSE REGULATOR receiver
FOB80_05320	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOB80_05325	COG4589	Belongs to the CDS family
FOB80_05330	COG0750	zinc metalloprotease
FOB80_05335	COG2176	DNA-directed DNA polymerase activity
FOB80_05355	COG0779	Required for maturation of 30S ribosomal subunits
FOB80_05360	COG0195	Participates in both transcription termination and antitermination
FOB80_05365	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FOB80_05380	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FOB80_05390	COG3759	membrane
FOB80_05400	COG0740	serine-type endopeptidase activity
FOB80_05405	COG2390	Transcriptional regulator
FOB80_05415	COG0126	phosphoglycerate kinase activity
FOB80_05420	COG0149	triose-phosphate isomerase activity
FOB80_05425	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FOB80_05430	COG0148	phosphopyruvate hydratase activity
FOB80_05435	COG4166	transmembrane transport
FOB80_05440	COG4166	transmembrane transport
FOB80_05450	COG0601	transmembrane transport
FOB80_05455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB80_05460	COG0444	Belongs to the ABC transporter superfamily
FOB80_05465	COG4608	Belongs to the ABC transporter superfamily
FOB80_05480	COG0557	exoribonuclease II activity
FOB80_05485	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FOB80_05490	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
FOB80_05495	COG0588	phosphoglycerate mutase activity
FOB80_05515	COG2826	transposase and inactivated derivatives, IS30 family
FOB80_05525	COG1401	restriction endodeoxyribonuclease activity
FOB80_05570	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOB80_05580	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOB80_05590	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOB80_05595	COG0439	Biotin carboxylase
FOB80_05600	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FOB80_05620	COG0116	Belongs to the methyltransferase superfamily
FOB80_05630	COG3599	regulation of cell shape
FOB80_05640	COG2264	protein methyltransferase activity
FOB80_05645	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOB80_05650	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOB80_05655	COG1490	D-aminoacyl-tRNA deacylase activity
FOB80_05665	COG0124	histidyl-tRNA synthetase
FOB80_05670	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FOB80_05685	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FOB80_05695	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FOB80_05700	COG0167	dihydroorotate dehydrogenase activity
FOB80_05705	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FOB80_05710	COG0346	lactoylglutathione lyase activity
FOB80_05715	COG0735	belongs to the Fur family
FOB80_05725	COG1610	YqeY-like protein
FOB80_05730	COG1028	Short-chain dehydrogenase reductase Sdr
FOB80_05745	COG1702	phosphate starvation-inducible protein PhoH
FOB80_05750	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FOB80_05760	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOB80_05765	COG1381	Involved in DNA repair and RecF pathway recombination
FOB80_05770	COG0752	glycyl-tRNA synthetase alpha subunit
FOB80_05775	COG0751	glycine-tRNA ligase activity
FOB80_05785	COG1234	tRNA 3'-trailer cleavage
FOB80_05790	COG4221	oxidoreductase activity
FOB80_05795	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOB80_05795	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FOB80_05800	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOB80_05830	COG4120	Belongs to the binding-protein-dependent transport system permease family
FOB80_05835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOB80_05835	COG1116	anion transmembrane transporter activity
FOB80_05850	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOB80_05855	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FOB80_05860	COG0494	nUDIX hydrolase
FOB80_05865	COG1349	DNA-binding transcription factor activity
FOB80_05870	COG1105	Belongs to the carbohydrate kinase PfkB family
FOB80_05875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB80_05875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB80_05875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB80_05880	COG1132	(ABC) transporter
FOB80_05885	COG1132	(ABC) transporter
FOB80_05895	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FOB80_05900	COG0765	amino acid transport
FOB80_05905	COG1126	abc transporter atp-binding protein
FOB80_05915	COG2207	Transcriptional regulator
FOB80_05925	COG1653	transport
FOB80_05930	COG1175	transmembrane transport
FOB80_05935	COG0395	ABC-type sugar transport system, permease component
FOB80_05940	COG0366	Alpha amylase catalytic
FOB80_05945	COG3842	ATPase activity
FOB80_05950	COG0366	Alpha amylase catalytic
FOB80_05955	COG1609	Transcriptional regulator
FOB80_05960	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FOB80_05965	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FOB80_06000	COG2086	electron transfer activity
FOB80_06005	COG1960	acyl-CoA dehydrogenase activity
FOB80_06020	COG1301	dicarboxylic acid transport
FOB80_06030	COG4974	Belongs to the 'phage' integrase family
FOB80_06040	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOB80_06045	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOB80_06050	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FOB80_06055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOB80_06060	COG0569	domain protein
FOB80_06065	COG1227	inorganic diphosphatase activity
FOB80_06080	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOB80_06085	COG0187	DNA topoisomerase II activity
FOB80_06100	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOB80_06105	COG0758	DNA mediated transformation
FOB80_06110	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FOB80_06125	COG3409	Peptidoglycan-binding domain 1 protein
FOB80_06125	COG0793	Belongs to the peptidase S41A family
FOB80_06150	COG0488	(ABC) transporter
FOB80_06170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOB80_06175	COG0717	Belongs to the dCTP deaminase family
FOB80_06195	COG0656	L-ascorbic acid biosynthetic process
FOB80_06200	COG0789	Transcriptional regulator
FOB80_06215	COG0484	heat shock protein binding
FOB80_06220	COG0443	Heat shock 70 kDa protein
FOB80_06225	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FOB80_06230	COG1420	regulation of RNA biosynthetic process
FOB80_06235	COG1473	amidohydrolase
FOB80_06240	COG0196	riboflavin kinase activity
FOB80_06245	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOB80_06255	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOB80_06260	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FOB80_06265	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FOB80_06270	COG0009	L-threonylcarbamoyladenylate synthase
FOB80_06275	COG2890	protein-(glutamine-N5) methyltransferase activity
FOB80_06280	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOB80_06285	COG1435	thymidine kinase activity
FOB80_06290	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOB80_06295	COG3442	glutamine amidotransferase
FOB80_06300	COG2135	peptidase activity
FOB80_06310	COG1132	(ABC) transporter
FOB80_06315	COG0628	permease
FOB80_06320	COG2706	6-phosphogluconolactonase activity
FOB80_06325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOB80_06345	COG1744	ABC transporter substrate-binding protein PnrA-like
FOB80_06350	COG1263	PTS System
FOB80_06350	COG2190	(PTS) system
FOB80_06350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB80_06355	COG1968	undecaprenyl-diphosphatase activity
FOB80_06360	COG0527	aspartate kinase activity
FOB80_06365	COG0297	glycogen (starch) synthase activity
FOB80_06370	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOB80_06375	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOB80_06390	COG0346	lactoylglutathione lyase activity
FOB80_06415	COG0683	leucine binding
FOB80_06420	COG2183	response to ionizing radiation
FOB80_06440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB80_06460	COG2826	transposase and inactivated derivatives, IS30 family
FOB80_06465	COG0018	arginyl-trna synthetase
FOB80_06475	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FOB80_06480	COG0577	efflux transmembrane transporter activity
FOB80_06480	COG1136	(ABC) transporter
FOB80_06490	COG0509	glycine decarboxylation via glycine cleavage system
FOB80_06495	COG0772	Belongs to the SEDS family
FOB80_06500	COG1295	ribonuclease BN
FOB80_06520	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FOB80_06525	COG0497	DNA recombination
FOB80_06530	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FOB80_06540	COG1722	exodeoxyribonuclease VII activity
FOB80_06545	COG1570	exodeoxyribonuclease VII activity
FOB80_06550	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FOB80_06555	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOB80_06565	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOB80_06570	COG0006	proline dipeptidase activity
FOB80_06595	COG4537	Required for transformation and DNA binding
FOB80_06600	COG1459	type II secretion system
FOB80_06605	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOB80_06620	COG1269	ATP hydrolysis coupled proton transport
FOB80_06650	COG1394	ATPase activity, coupled to movement of substances
FOB80_06655	COG0217	transcriptional regulatory protein
FOB80_06660	COG1597	lipid kinase activity
FOB80_06665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOB80_06680	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOB80_06685	COG0656	L-ascorbic acid biosynthetic process
FOB80_06695	COG3830	Belongs to the UPF0237 family
FOB80_06700	COG2843	Capsule synthesis protein
FOB80_06720	COG0668	transmembrane transport
FOB80_06725	COG0622	Phosphoesterase
FOB80_06730	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FOB80_06745	COG3118	belongs to the thioredoxin family
FOB80_06750	COG1193	negative regulation of DNA recombination
FOB80_06785	COG2199	diguanylate cyclase activity
FOB80_06800	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOB80_06805	COG1720	tRNA m6t6A37 methyltransferase activity
FOB80_06815	COG2176	DNA-directed DNA polymerase activity
FOB80_06820	COG1671	Belongs to the UPF0178 family
FOB80_06830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOB80_06835	COG0765	amino acid transport
FOB80_06840	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOB80_06850	COG0561	phosphatase activity
FOB80_06855	COG2826	transposase and inactivated derivatives, IS30 family
FOB80_06870	COG1737	Transcriptional regulator
FOB80_06875	COG0673	inositol 2-dehydrogenase activity
FOB80_06880	COG0673	inositol 2-dehydrogenase activity
FOB80_06885	COG0584	glycerophosphoryl diester phosphodiesterase
FOB80_06890	COG3842	ATPase activity
FOB80_06900	COG1175	transmembrane transport
FOB80_06925	COG1764	response to oxidative stress
FOB80_06930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOB80_06935	COG2040	homocysteine
FOB80_06940	COG0833	amino acid
FOB80_06975	COG4974	Belongs to the 'phage' integrase family
FOB80_07000	COG1304	FMN binding
FOB80_07010	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FOB80_07015	COG1122	ATPase activity
FOB80_07020	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOB80_07035	COG0802	atpase or kinase
FOB80_07040	COG0280	phosphate acetyltransferase
FOB80_07045	COG1070	Carbohydrate kinase
FOB80_07050	COG0072	phenylalanine-tRNA ligase activity
FOB80_07055	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FOB80_07060	COG1733	regulation of RNA biosynthetic process
FOB80_07070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOB80_07080	COG1187	pseudouridine synthase activity
FOB80_07085	COG2244	polysaccharide biosynthetic process
FOB80_07095	COG0495	leucyl-tRNA aminoacylation
FOB80_07100	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FOB80_07110	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FOB80_07115	COG1388	LysM domain
FOB80_07115	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOB80_07120	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FOB80_07130	COG1278	Cold shock
FOB80_07135	COG2003	Belongs to the UPF0758 family
FOB80_07150	COG0582	viral genome integration into host DNA
FOB80_07165	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOB80_07170	COG1131	(ABC) transporter
FOB80_07195	COG2226	methyltransferase
FOB80_07205	COG0582	viral genome integration into host DNA
FOB80_07215	COG4974	Belongs to the 'phage' integrase family
FOB80_07225	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FOB80_07230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB80_07240	COG0525	valine-tRNA ligase activity
FOB80_07245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOB80_07250	COG1940	carbohydrate kinase activity
FOB80_07255	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOB80_07260	COG0705	Rhomboid family
FOB80_07260	COG0457	Tetratricopeptide repeat
FOB80_07265	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOB80_07270	COG0768	penicillin binding
FOB80_07280	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOB80_07290	COG0513	Belongs to the DEAD box helicase family
FOB80_07295	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOB80_07300	COG1744	ABC transporter substrate-binding protein PnrA-like
FOB80_07305	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOB80_07310	COG4109	DRTGG domain
FOB80_07330	COG1862	Preprotein translocase
FOB80_07335	COG0343	queuine tRNA-ribosyltransferase activity
FOB80_07350	COG4864	UPF0365 protein
FOB80_07360	COG0542	response to heat
FOB80_07370	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOB80_07380	COG1733	regulation of RNA biosynthetic process
FOB80_07390	COG1937	Protein conserved in bacteria
FOB80_07395	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOB80_07400	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOB80_07420	COG1132	(ABC) transporter
FOB80_07425	COG1132	(ABC) transporter
FOB80_07435	COG0151	Belongs to the GarS family
FOB80_07440	COG0138	bifunctional purine biosynthesis protein purh
FOB80_07445	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOB80_07450	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FOB80_07455	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOB80_07460	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOB80_07480	COG0673	inositol 2-dehydrogenase activity
FOB80_07490	COG0038	chloride channel
FOB80_07495	COG0335	large ribosomal subunit rRNA binding
FOB80_07500	COG0469	pyruvate kinase activity
FOB80_07515	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FOB80_07520	COG1837	Belongs to the UPF0109 family
FOB80_07530	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOB80_07535	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FOB80_07540	COG2197	response regulator
FOB80_07545	COG4585	Histidine kinase
FOB80_07550	COG1131	(ABC) transporter
FOB80_07565	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOB80_07570	COG1940	carbohydrate kinase activity
FOB80_07575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOB80_07580	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FOB80_07585	COG4894	glucomannan catabolic process
FOB80_07595	COG0642	Histidine kinase
FOB80_07600	COG1136	(ABC) transporter
FOB80_07615	COG0552	protein localization to endoplasmic reticulum
FOB80_07620	COG0561	phosphatase activity
FOB80_07625	COG1196	nuclear chromosome segregation
FOB80_07630	COG0571	ribonuclease III activity
FOB80_07635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOB80_07640	COG0416	fatty acid biosynthetic process
FOB80_07645	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOB80_07650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB80_07675	COG0708	Exodeoxyribonuclease III
FOB80_07680	COG1454	alcohol dehydrogenase
FOB80_07680	COG1012	belongs to the aldehyde dehydrogenase family
FOB80_07685	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOB80_07690	COG1882	Formate acetyltransferase
FOB80_07695	COG2151	metal-sulfur cluster biosynthetic enzyme
FOB80_07760	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FOB80_07765	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOB80_07775	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOB80_07830	COG0438	transferase activity, transferring glycosyl groups
FOB80_07835	COG0438	transferase activity, transferring glycosyl groups
FOB80_07840	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOB80_07850	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FOB80_07860	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOB80_07890	COG1216	Glycosyl transferase, family 2
FOB80_07900	COG0110	maltose O-acetyltransferase activity
FOB80_07915	COG1216	Glycosyl transferase, family 2
FOB80_07925	COG0438	transferase activity, transferring glycosyl groups
FOB80_07940	COG0438	transferase activity, transferring glycosyl groups
FOB80_07945	COG0728	peptidoglycan biosynthetic process
FOB80_07950	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FOB80_07950	COG0662	Cupin 2, conserved barrel domain protein
FOB80_07955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOB80_07965	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOB80_07985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOB80_08015	COG1562	ergosterol biosynthetic process
FOB80_08030	COG1461	Dihydroxyacetone kinase
FOB80_08035	COG1302	Protein conserved in bacteria
FOB80_08040	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FOB80_08045	COG1564	THIamine pyrophosphokinase
FOB80_08050	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOB80_08055	COG1162	GTPase activity
FOB80_08065	COG0631	protein serine/threonine phosphatase activity
FOB80_08070	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOB80_08070	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOB80_08075	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOB80_08080	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOB80_08090	COG0402	S-adenosylhomocysteine deaminase activity
FOB80_08095	COG1758	RNA polymerase activity
FOB80_08100	COG0194	GDP metabolic process
FOB80_08110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB80_08125	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOB80_08130	COG1185	polyribonucleotide nucleotidyltransferase activity
FOB80_08135	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FOB80_08140	COG0671	phosphoesterase, PA-phosphatase related
FOB80_08145	COG0556	nucleotide-excision repair
FOB80_08150	COG0268	Binds directly to 16S ribosomal RNA
FOB80_08155	COG1466	dna polymerase III delta subunit
FOB80_08160	COG0658	competence protein
FOB80_08160	COG2333	competence protein COMEC
FOB80_08165	COG1555	photosystem II stabilization
FOB80_08165	COG1596	polysaccharide export
FOB80_08170	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FOB80_08175	COG0742	ribosomal rna small subunit methyltransferase
FOB80_08205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOB80_08210	COG0783	Belongs to the Dps family
FOB80_08230	COG4471	UPF0298 protein
FOB80_08235	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FOB80_08240	COG0772	Belongs to the SEDS family
FOB80_08250	COG0483	inositol monophosphate 1-phosphatase activity
FOB80_08255	COG4476	Belongs to the UPF0223 family
FOB80_08280	COG0022	dehydrogenase e1 component
FOB80_08290	COG0242	peptide deformylase activity
FOB80_08295	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOB80_08325	COG3425	synthase
FOB80_08330	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOB80_08335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOB80_08345	COG0765	amino acid transport
FOB80_08350	COG0765	amino acid transport
FOB80_08355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB80_08390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOB80_08400	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOB80_08420	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOB80_08440	COG1116	anion transmembrane transporter activity
FOB80_08445	COG4120	Belongs to the binding-protein-dependent transport system permease family
FOB80_08460	COG1876	peptidase activity
FOB80_08465	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOB80_08470	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FOB80_08475	COG0252	asparaginase activity
FOB80_08485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB80_08495	COG0489	protein tyrosine kinase activity
FOB80_08510	COG4464	protein tyrosine phosphatase activity
FOB80_08515	COG1051	belongs to the nudix hydrolase family
FOB80_08525	COG1307	EDD domain protein, DegV family
FOB80_08545	COG0516	GMP reductase activity
FOB80_08550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB80_08555	COG1316	TRANSCRIPTIONal
FOB80_08560	COG1316	TRANSCRIPTIONal
FOB80_08565	COG0024	Methionine aminopeptidase
FOB80_08575	COG0716	FMN binding
FOB80_08580	COG2309	aminopeptidase activity
FOB80_08620	COG1442	glycosyl transferase family 8
FOB80_08620	COG1216	Glycosyl transferase, family 2
FOB80_08640	COG2089	acid synthase
FOB80_08645	COG1083	cytidylyl-transferase
FOB80_08650	COG4166	transmembrane transport
FOB80_08655	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FOB80_08665	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOB80_08670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOB80_08675	COG1121	(ABC) transporter
FOB80_08680	COG3443	Belongs to the bacterial solute-binding protein 9 family
FOB80_08680	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOB80_08685	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FOB80_08690	COG4466	Protein conserved in bacteria
FOB80_08695	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOB80_08705	COG0084	hydrolase, TatD family'
FOB80_08710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB80_08710	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB80_08720	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOB80_08730	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOB80_08740	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FOB80_08765	COG2738	Putative neutral zinc metallopeptidase
FOB80_08785	COG1335	isochorismatase
FOB80_08790	COG0436	Aminotransferase
FOB80_08795	COG1522	sequence-specific DNA binding
FOB80_08810	COG1966	Carbon starvation protein
FOB80_08815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOB80_08820	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FOB80_08825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOB80_08830	COG0569	domain protein
FOB80_08835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOB80_08840	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOB80_08850	COG4853	Protein conserved in bacteria
FOB80_08860	COG5002	protein histidine kinase activity
FOB80_08865	COG0745	RESPONSE REGULATOR receiver
FOB80_08890	COG1073	alpha beta
FOB80_08895	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOB80_08900	COG0628	permease
FOB80_08915	COG0588	phosphoglycerate mutase activity
FOB80_08940	COG3527	Alpha-acetolactate decarboxylase
FOB80_08965	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOB80_08970	COG4807	Protein conserved in bacteria
FOB80_08985	COG0753	catalase activity
FOB80_08990	COG1902	pentaerythritol trinitrate reductase activity
FOB80_09005	COG1028	Short-chain dehydrogenase reductase Sdr
FOB80_09010	COG0110	maltose O-acetyltransferase activity
FOB80_09015	COG0583	DNA-binding transcription factor activity
FOB80_09025	COG0564	pseudouridine synthase activity
FOB80_09030	COG4720	Psort location CytoplasmicMembrane, score
FOB80_09035	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOB80_09040	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOB80_09070	COG0159	tryptophan synthase activity
FOB80_09075	COG0133	tryptophan synthase activity
FOB80_09095	COG0512	Glutamine amidotransferase of anthranilate synthase
FOB80_09095	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOB80_09110	COG4895	conserved protein (DUF2196)
FOB80_09120	COG1523	belongs to the glycosyl hydrolase 13 family
FOB80_09125	COG3316	Transposase and inactivated derivatives
FOB80_09135	COG1959	2 iron, 2 sulfur cluster binding
FOB80_09150	COG2321	neutral zinc metallopeptidase
FOB80_09165	COG0778	Nitroreductase
FOB80_09175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB80_09200	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOB80_09215	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOB80_09230	COG1827	regulation of RNA biosynthetic process
FOB80_09240	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOB80_09245	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOB80_09250	COG0154	amidase activity
FOB80_09260	COG4851	CamS sex pheromone cAM373 precursor
FOB80_09265	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOB80_09270	COG0210	DNA helicase
FOB80_09280	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOB80_09290	COG0411	ABC transporter
FOB80_09300	COG0559	Belongs to the binding-protein-dependent transport system permease family
FOB80_09325	COG0737	Belongs to the 5'-nucleotidase family
FOB80_09340	COG1960	acyl-CoA dehydrogenase activity
FOB80_09350	COG0583	DNA-binding transcription factor activity
FOB80_09355	COG1024	Enoyl-CoA hydratase
FOB80_09360	COG0183	Belongs to the thiolase family
FOB80_09365	COG1024	Enoyl-CoA hydratase
FOB80_09365	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOB80_09370	COG1960	acyl-CoA dehydrogenase activity
FOB80_09390	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FOB80_09400	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOB80_09410	COG5002	protein histidine kinase activity
FOB80_09410	COG3850	Histidine kinase
FOB80_09415	COG0745	RESPONSE REGULATOR receiver
FOB80_09420	COG0629	single-stranded DNA binding
FOB80_09430	COG1481	regulation of sporulation
FOB80_09435	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FOB80_09440	COG1660	Displays ATPase and GTPase activities
FOB80_09445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOB80_09450	COG0492	ferredoxin-NADP+ reductase activity
FOB80_09455	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOB80_09460	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FOB80_09465	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FOB80_09470	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FOB80_09480	COG1983	PspC domain protein
FOB80_09495	COG0419	ATPase involved in DNA repair
FOB80_09500	COG0420	3'-5' exonuclease activity
FOB80_09505	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOB80_09510	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOB80_09515	COG0581	inorganic phosphate transmembrane transporter activity
FOB80_09520	COG0573	inorganic phosphate transmembrane transporter activity
FOB80_09525	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOB80_09530	COG5002	protein histidine kinase activity
FOB80_09535	COG0745	RESPONSE REGULATOR receiver
FOB80_09540	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FOB80_09545	COG0653	protein targeting
FOB80_09560	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FOB80_09565	COG1307	EDD domain protein, DegV family
FOB80_09570	COG1739	Uncharacterized protein family UPF0029
FOB80_09575	COG0277	FAD linked oxidase domain protein
FOB80_09615	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOB80_09620	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOB80_09630	COG0765	amino acid transport
FOB80_09635	COG0431	NADPH-dependent FMN reductase
FOB80_09645	COG0765	amino acid transport
FOB80_09650	COG0165	Argininosuccinate lyase
FOB80_09660	COG0459	protein refolding
FOB80_09665	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FOB80_09680	COG0488	(ABC) transporter
FOB80_09700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid