locus-tag	class	description
C3E78_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
C3E78_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
C3E78_00015	ENOG4108J5G	6-phosphogluconate dehydrogenase
C3E78_00020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
C3E78_00025	ENOG4105K7N	UPF0232 protein
C3E78_00035	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C3E78_00040	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C3E78_00045	ENOG4108ZED	Transmembrane domain of unknown function (DUF3566)
C3E78_00085	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
C3E78_00105	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C3E78_00110	ENOG4108J59	Extracellular solute-binding protein, family 5
C3E78_00125	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
C3E78_00140	ENOG4105E39	Enoyl-CoA hydratase
C3E78_00145	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
C3E78_00155	ENOG4105ZJT	Cell division protein CrgA
C3E78_00170	ENOG4105CJN	penicillin-binding protein
C3E78_00185	ENOG4105HZM	Fha domain containing protein
C3E78_00190	ENOG4105TV9	FHA Domain-Containing protein
C3E78_00200	ENOG4107QNK	)-transporter
C3E78_00220	ENOG4108Z0Z	intracellular protease Pfpi family
C3E78_00230	ENOG4105E39	Enoyl-CoA hydratase
C3E78_00245	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
C3E78_00255	ENOG4105C57	major facilitator superfamily
C3E78_00265	ENOG4108594	Permease of the drug metabolite transporter
C3E78_00270	ENOG4108RZE	Tetr family transcriptional regulator
C3E78_00275	ENOG4107QX3	carboxylase
C3E78_00285	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
C3E78_00295	ENOG4107GJV	short-chain dehydrogenase reductase
C3E78_00305	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
C3E78_00310	ENOG4108426	dNA-binding protein
C3E78_00320	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
C3E78_00335	ENOG4105CEU	Arginine dihydrolase
C3E78_00355	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
C3E78_00360	ENOG4105CBD	Diacylglycerol kinase
C3E78_00365	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
C3E78_00370	ENOG410667J	hydrolase
C3E78_00375	ENOG4105KVH	Transcriptional regulator
C3E78_00380	ENOG4107S5I	aldo keto reductase
C3E78_00385	ENOG4107ZED	Uncharacterised protein family UPF0047
C3E78_00410	ENOG4107QPI	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
C3E78_00435	ENOG4105KDM	Diguanylate cyclase with gaf sensor
C3E78_00470	ENOG4108QV3	biosynthesis protein
C3E78_00495	ENOG4105CPK	Glycosyl transferase (Group 1
C3E78_00510	ENOG4105D3Q	Sugar transferase
C3E78_00525	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C3E78_00550	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
C3E78_00565	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C3E78_00570	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
C3E78_00585	ENOG4108UHU	Aldolase
C3E78_00590	ENOG4105KME	endoribonuclease L-psp
C3E78_00595	ENOG4107S1E	Beta-lactamase
C3E78_00615	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C3E78_00620	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C3E78_00645	ENOG4105VC4	domain protein
C3E78_00650	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
C3E78_00660	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
C3E78_00680	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C3E78_00725	ENOG4105EXC	Acyl-transferase
C3E78_00745	ENOG4105WN5	stage II sporulation protein
C3E78_00750	ENOG4105BZU	Histidine kinase
C3E78_00755	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
C3E78_00800	ENOG4105FDF	Could be involved in DNA repair (By similarity)
C3E78_00805	ENOG4105EQK	-acetyltransferase
C3E78_00810	ENOG4105C26	Dehydrogenase
C3E78_00820	ENOG4108JPW	Aminotransferase
C3E78_00825	ENOG4105DND	Transcriptional regulator
C3E78_00845	ENOG4105CHR	reductase
C3E78_00860	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
C3E78_00865	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
C3E78_00870	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
C3E78_00880	ENOG4108FWV	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
C3E78_00890	ENOG4105DEN	Luciferase family
C3E78_00900	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
C3E78_00905	ENOG4108UZX	fmn reductase
C3E78_00910	ENOG4105CS9	pantothenic acid kinase
C3E78_00925	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
C3E78_00935	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C3E78_00970	ENOG4105EMU	Dehydrogenase
C3E78_00975	ENOG4107RDP	Dehydrogenase
C3E78_00985	ENOG4105CPP	Dehydrogenase, E1 component
C3E78_00990	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
C3E78_01010	ENOG4107S5I	aldo keto reductase
C3E78_01055	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
C3E78_01090	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
C3E78_01165	ENOG4108UKI	Enoyl-CoA hydratase
C3E78_01175	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
C3E78_01190	ENOG4108UKI	Enoyl-CoA hydratase
C3E78_01195	ENOG4105CEY	Amp-dependent synthetase and ligase
C3E78_01205	ENOG4105CHR	reductase
C3E78_01215	ENOG4105D2B	acyl-CoA dehydrogenase
C3E78_01220	ENOG4105CC9	acyl-Coa dehydrogenase
C3E78_01225	ENOG4105CHU	acetyl-coa acetyltransferase
C3E78_01245	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
C3E78_01270	ENOG4105X7H	acyl-CoA dehydrogenase
C3E78_01290	ENOG4105CRQ	synthase (Component I)
C3E78_01310	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
C3E78_01315	ENOG4105CFH	Aspartokinase
C3E78_01325	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C3E78_01335	ENOG4105DIN	metallophosphoesterase
C3E78_01345	ENOG4105BZ4	penicillin-binding protein
C3E78_01350	ENOG4105N0U	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
C3E78_01380	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
C3E78_01395	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C3E78_01400	ENOG4105P8F	nudix hydrolase
C3E78_01405	ENOG4105C0H	protease
C3E78_01420	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C3E78_01430	ENOG4107QN1	sodium solute
C3E78_01450	ENOG4108NEV	two component transcriptional regulator, LytTR family
C3E78_01455	ENOG4108HRK	Histidine kinase
C3E78_01460	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
C3E78_01465	ENOG4108JJB	ABC transporter
C3E78_01470	ENOG4105VKD	bioY protein
C3E78_01540	ENOG4105EXC	Acyl-transferase
C3E78_01545	ENOG4108I5C	dEAD DEAH box helicase
C3E78_01550	ENOG4105WN5	stage II sporulation protein
C3E78_01555	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
C3E78_01560	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C3E78_01580	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
C3E78_01585	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
C3E78_01590	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
C3E78_01595	ENOG4105C6E	dna polymerase iii
C3E78_01605	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
C3E78_01625	ENOG4108Z40	Transcriptional regulator
C3E78_01630	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
C3E78_01645	ENOG4105KVH	Transcriptional regulator
C3E78_01660	ENOG4105D9P	serine threonine protein kinase
C3E78_01665	ENOG41085FC	arsR family transcriptional regulator
C3E78_01675	ENOG4108UXE	Protein tyrosine phosphatase
C3E78_01690	ENOG4106UW1	Major Facilitator superfamily
C3E78_01695	ENOG4108U4N	(sortase) family
C3E78_01700	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
C3E78_01715	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
C3E78_01735	ENOG4107TE5	Lipid kinase
C3E78_01750	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
C3E78_01755	ENOG4105C12	Phosphoribosylglycinamide synthetase
C3E78_01760	ENOG4105C83	adenylosuccinate lyase
C3E78_01770	ENOG4105C8V	SAICAR synthetase
C3E78_01775	ENOG4105CEY	Amp-dependent synthetase and ligase
C3E78_01780	ENOG410839H	phosphoribosylformylglycinamidine synthase
C3E78_01785	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
C3E78_01855	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C3E78_01860	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
C3E78_01880	ENOG4105CEY	Amp-dependent synthetase and ligase
C3E78_01895	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
C3E78_01920	ENOG4105K56	Transcriptional regulator
C3E78_01925	ENOG4108R86	Transcriptional regulator
C3E78_01945	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
C3E78_01970	ENOG4108IJ8	ABC transporter
C3E78_01975	ENOG4105E90	ABC transporter
C3E78_01990	ENOG4107WA4	MmpL domain-containing protein
C3E78_02000	ENOG4105WH1	Two component transcriptional regulator luxr family
C3E78_02010	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
C3E78_02015	ENOG4105KD7	acetyltransferase
C3E78_02025	ENOG4105WN5	stage II sporulation protein
C3E78_02030	ENOG4107E6A	Cytochrome p-450
C3E78_02045	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
C3E78_02080	ENOG4106PVI	ATP-dependent carboxylate-amine ligase (By similarity)
C3E78_02100	ENOG4107U9T	Pfam:Ribonuclease_BN
C3E78_02115	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
C3E78_02120	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C3E78_02135	ENOG4105EXC	Acyl-transferase
C3E78_02145	ENOG4105CPC	Aldo Keto reductase
C3E78_02155	ENOG4108XFH	Transcriptional regulator
C3E78_02185	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
C3E78_02195	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
C3E78_02200	ENOG4105K64	Glycosyl transferase, family 2
C3E78_02205	ENOG4107QQG	Dehydrogenase
C3E78_02210	ENOG4105EXC	Acyl-transferase
C3E78_02250	ENOG4108Z86	Glutamine amidotransferase
C3E78_02255	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
C3E78_02265	ENOG4105D74	hydrolase
C3E78_02280	ENOG4105MHT	Transcriptional regulator, ARSR family
C3E78_02300	ENOG4107TB5	TRANSCRIPTIONal
C3E78_02385	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
C3E78_02410	ENOG4105CBC	glutamate synthase
C3E78_02420	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C3E78_02450	ENOG4105BZU	Histidine kinase
C3E78_02470	ENOG4105CJ3	phosphate transporter
C3E78_02475	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
C3E78_02490	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
C3E78_02505	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
C3E78_02515	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
C3E78_02525	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
C3E78_02535	ENOG4105JXH	GntR family transcriptional regulator
C3E78_02540	ENOG4105EJ9	Membrane
C3E78_02545	ENOG4107NHD	transcriptional regulator
C3E78_02580	ENOG4105CPK	Glycosyl transferase (Group 1
C3E78_02595	ENOG4105D3Q	Sugar transferase
C3E78_02600	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
C3E78_02610	ENOG4107YJ4	chain length determinant protein
C3E78_02630	ENOG4105KHC	sulfurtransferase
C3E78_02635	ENOG4105PKJ	carbohydrate binding
C3E78_02640	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
C3E78_02645	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
C3E78_02650	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
C3E78_02660	ENOG4107YJ4	chain length determinant protein
C3E78_02670	ENOG4105EIP	mannose-6-phosphate isomerase
C3E78_02675	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
C3E78_02720	ENOG4105C94	Transporter
C3E78_02750	ENOG4105CI3	gtp-binding protein typa
C3E78_02760	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C3E78_02765	ENOG4105CEY	Amp-dependent synthetase and ligase
C3E78_02775	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
C3E78_02790	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
C3E78_02815	ENOG4108VJ1	Transcriptional regulator (CarD family
C3E78_02820	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
C3E78_02835	ENOG4105C8N	cysteinyl-tRNA synthetase
C3E78_02845	ENOG41076PI	Short-chain dehydrogenase reductase Sdr
C3E78_02880	ENOG4105CEY	Amp-dependent synthetase and ligase
C3E78_02885	ENOG4105E39	Enoyl-CoA hydratase
C3E78_02895	ENOG4105C1G	acyl-Coa dehydrogenase
C3E78_02900	ENOG410846T	CoA-transferase family III
C3E78_02905	ENOG4105DQ4	alcohol dehydrogenase
C3E78_02930	ENOG4105CHU	acetyl-coa acetyltransferase
C3E78_02945	ENOG4108IG5	Transcriptional regulator
C3E78_02955	ENOG4105C32	Amino acid ABC transporter (Permease)
C3E78_02960	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
C3E78_02965	ENOG4105C0Z	ABC transporter
C3E78_02970	ENOG4108IV0	ABC, transporter
C3E78_02985	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
C3E78_03015	ENOG41069M3	Transcriptional regulator
C3E78_03055	ENOG41060BG	Tetr family transcriptional regulator
C3E78_03060	ENOG4108IXY	short-chain dehydrogenase reductase
C3E78_03070	ENOG4105BZU	Histidine kinase
C3E78_03075	ENOG4105DY8	decarboxylase
C3E78_03085	ENOG4108KEZ	Dehydrogenase
C3E78_03090	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C3E78_03105	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
C3E78_03120	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
C3E78_03125	ENOG4105EC3	peptidase S51, dipeptidase E
C3E78_03135	ENOG4105C02	permease
C3E78_03140	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
C3E78_03145	ENOG4106UW1	Major Facilitator superfamily
C3E78_03155	ENOG4105DCF	alanine dehydrogenase
C3E78_03180	ENOG4105CVK	Glutamate decarboxylase
C3E78_03195	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
C3E78_03230	ENOG4105VEQ	Cold shock protein
C3E78_03265	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
C3E78_03270	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
C3E78_03285	ENOG4105D7W	serine acetyltransferase
C3E78_03290	ENOG4107RR1	TRANSCRIPTIONal
C3E78_03295	ENOG4105C26	Dehydrogenase
C3E78_03345	ENOG4105D3Q	Sugar transferase
C3E78_03350	ENOG4105CEY	Amp-dependent synthetase and ligase
C3E78_03360	ENOG4105EMN	RNA polymerase sigma factor
C3E78_03375	ENOG4105VEQ	Cold shock protein
C3E78_03380	ENOG4108N0W	Major Facilitator superfamily
C3E78_03405	ENOG4105C7N	Xanthine uracil vitamin C permease
C3E78_03410	ENOG4108Z0R	Transferase
C3E78_03415	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
C3E78_03450	ENOG4108SHN	Glycosyl transferase, family 2
C3E78_03460	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
C3E78_03485	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
C3E78_03500	ENOG4107QN2	dihydrolipoyl dehydrogenase
C3E78_03515	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
C3E78_03575	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
C3E78_03590	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C3E78_03595	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
C3E78_03660	ENOG4105EEF	Alkane 1-monooxygenase
C3E78_03665	ENOG41084UD	rubredoxin
C3E78_03670	ENOG4105VCQ	rubredoxin
C3E78_03720	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
C3E78_03725	ENOG4105F8V	Hydrolase, tatD family
C3E78_03735	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
C3E78_03740	ENOG4105XPP	Protein of unknown function (DUF1275)
C3E78_03750	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
C3E78_03760	ENOG4107SCK	Monooxygenase
C3E78_03770	ENOG4105C5H	ABC transporter
C3E78_03785	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
C3E78_03795	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
C3E78_03810	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
C3E78_03815	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
C3E78_03820	ENOG4105D3Q	Sugar transferase
C3E78_03900	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
C3E78_03905	ENOG4107RGC	Glycosyl transferase, family 2
C3E78_03925	ENOG4108SHN	Glycosyl transferase, family 2
C3E78_03935	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
C3E78_03960	ENOG4108KGH	TRANSCRIPTIONal
C3E78_03980	ENOG4105CUB	amino acid
C3E78_03995	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
C3E78_04030	ENOG4105DEI	Mannitol dehydrogenase
C3E78_04040	ENOG4105ETE	Transcriptional regulator (LacI family
C3E78_04045	ENOG4105C2J	ABC transporter
C3E78_04050	ENOG41071MT	Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane
C3E78_04055	ENOG41071MT	Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane
C3E78_04080	ENOG4105DET	Rhamnulokinase
C3E78_04095	ENOG4105F9U	Dehydrogenase
C3E78_04100	ENOG4105C10	Electron transfer flavoprotein
C3E78_04105	ENOG4105BZJ	Electron transfer flavoprotein
C3E78_04120	ENOG4108HQS	Glycine betaine
C3E78_04125	ENOG4108IJ7	Glycine betaine
C3E78_04135	ENOG4105C26	Dehydrogenase
C3E78_04140	ENOG4107HP6	Transcriptional regulator
C3E78_04150	ENOG4105F5V	trimethylamine methyltransferase
C3E78_04160	ENOG4108Q52	Methyltransferase cognate corrinoid protein
C3E78_04195	ENOG4107SET	aldo keto reductase
C3E78_04205	ENOG4106YT9	Enoyl-CoA hydratase
C3E78_04215	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
C3E78_04235	ENOG4105EUB	pirin domain protein
C3E78_04245	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
C3E78_04250	ENOG4105ECR	NmrA family
C3E78_04255	ENOG4105KVH	Transcriptional regulator
C3E78_04260	ENOG4108VCA	G U mismatch-specific DNA glycosylase
C3E78_04265	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
C3E78_04275	ENOG4105MSB	protein, conserved in bacteria
C3E78_04330	ENOG410834F	Transcriptional regulator
C3E78_04335	ENOG4105EYF	MMPL domain protein
C3E78_04350	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C3E78_04355	ENOG4105C3U	ABC transporter
C3E78_04380	ENOG4105DTQ	mandelate racemase muconate lactonizing
C3E78_04395	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C3E78_04405	ENOG4105WH1	Two component transcriptional regulator luxr family
C3E78_04415	ENOG4108YXU	transcriptional regulator AsnC family
C3E78_04430	ENOG4105CND	Glycosyl transferase, family 2
C3E78_04440	ENOG4105BZU	Histidine kinase
C3E78_04450	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C3E78_04485	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
C3E78_04490	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
C3E78_04530	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
C3E78_04555	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
C3E78_04580	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
C3E78_04585	ENOG4105NTW	Transcriptional regulator
C3E78_04590	ENOG41080XQ	Signal transduction protein with cbs domains
C3E78_04595	ENOG4107TK4	histidinol-phosphate phosphatase
C3E78_04600	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
C3E78_04605	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
C3E78_04615	ENOG4108RAV	Conserved protein
C3E78_04620	ENOG4105EMN	RNA polymerase sigma factor
C3E78_04655	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
C3E78_04675	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
C3E78_04680	ENOG4105CNN	ABC, transporter
C3E78_04685	ENOG4105C2J	ABC transporter
C3E78_04690	ENOG4105E2R	ROK family
C3E78_04695	ENOG4105CAK	Cell division ATP-binding protein ftsE
C3E78_04700	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
C3E78_04715	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
C3E78_04740	ENOG4105KZX	Pterin carbinolamine dehydratase
C3E78_04750	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
C3E78_04755	ENOG4107QRT	dEAD DEAH box helicase
C3E78_04775	ENOG4108R5T	secreted protein
C3E78_04780	ENOG4108Q5F	Tetr family transcriptional regulator
C3E78_04795	ENOG4108UJU	UPF0301 protein
C3E78_04830	ENOG4105DEN	Luciferase family
C3E78_04845	ENOG4108RWI	nicotinamidase
C3E78_04855	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
C3E78_04885	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
C3E78_04890	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
C3E78_04895	ENOG4108RQ5	Beta-lactamase domain-containing protein
C3E78_04900	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
C3E78_04905	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
C3E78_04920	ENOG4105DKK	Benzoate
C3E78_04955	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
C3E78_04965	ENOG4105G6Z	alkaline phosphatase
C3E78_04975	ENOG4105CI0	Citrate lyase
C3E78_04990	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
C3E78_04995	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
C3E78_05000	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
C3E78_05025	ENOG4105SCY	DNAK suppressor
C3E78_05045	ENOG4105EUB	pirin domain protein
C3E78_05055	ENOG4105GCF	PGAM
C3E78_05060	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
C3E78_05065	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
C3E78_05080	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
C3E78_05090	ENOG41083TI	Protein CrcB homolog
C3E78_05095	ENOG4107JBM	CrcB-like protein
C3E78_05115	ENOG4105W0E	50S ribosomal protein L33
C3E78_05135	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
C3E78_05160	ENOG4108YYC	ycei family
C3E78_05170	ENOG4105C1G	acyl-Coa dehydrogenase
C3E78_05175	ENOG4105CHU	acetyl-coa acetyltransferase
C3E78_05180	ENOG4105CHR	reductase
C3E78_05185	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
C3E78_05190	ENOG4105IBS	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
C3E78_05220	ENOG4105D8K	carboxyl transferase
C3E78_05225	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
C3E78_05235	ENOG4108Z18	K06886 hemoglobin
C3E78_05240	ENOG4105D8X	mechanosensitive ion channel
C3E78_05255	ENOG4105C1G	acyl-Coa dehydrogenase
C3E78_05265	ENOG4105EA8	2-Nitropropane dioxygenase
C3E78_05270	ENOG4105C3Q	Glycosyl transferase, family 2
C3E78_05275	ENOG4105EEI	dihydropteroate synthase
C3E78_05285	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
C3E78_05290	ENOG4105MC2	DSBA oxidoreductase
C3E78_05335	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
C3E78_05355	ENOG4105FDP	GntR family transcriptional regulator
C3E78_05365	ENOG4105EDK	PfkB domain protein
C3E78_05375	ENOG4105DH8	myo-inositol catabolism
C3E78_05380	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
C3E78_05385	ENOG4105C26	Dehydrogenase
C3E78_05395	ENOG4105CNN	ABC, transporter
C3E78_05400	ENOG4105C2J	ABC transporter
C3E78_05405	ENOG4106448	streptomycin biosynthesis protein strI
C3E78_05410	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
C3E78_05420	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
C3E78_05425	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
C3E78_05440	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
C3E78_05445	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C3E78_05450	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C3E78_05455	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
C3E78_05460	ENOG4105EG6	Saccharopine dehydrogenase
C3E78_05465	ENOG410849S	phosphocarrier protein (HPr)
C3E78_05470	ENOG4105DE4	1-phosphofructokinase
C3E78_05475	ENOG4105E98	transcriptional regulator DeoR family
C3E78_05480	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
C3E78_05485	ENOG4105CPQ	Dehydrogenase
C3E78_05490	ENOG4105JF0	Phosphoenolpyruvate-dependent sugar phosphotransferase system, eiia 2
C3E78_05515	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
C3E78_05520	ENOG4105EYF	MMPL domain protein
C3E78_05525	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
C3E78_05565	ENOG4105CG3	alpha amylase, catalytic region
C3E78_05570	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
C3E78_05590	ENOG4105CKK	Glycosyl transferase, family 2
C3E78_05610	ENOG4107RZX	Teichoic acid biosynthesis protein
C3E78_05615	ENOG4107RZX	Teichoic acid biosynthesis protein
C3E78_05630	ENOG4105DJ2	Major Facilitator Superfamily
C3E78_05640	ENOG4105C03	ribonuclease
C3E78_05645	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
C3E78_05650	ENOG4105K46	50S ribosomal protein l27
C3E78_05655	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C3E78_05660	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
C3E78_05665	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
C3E78_05670	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
C3E78_05680	ENOG4105CVJ	phosphoglycerate mutase
C3E78_05720	ENOG4105DXI	Major Facilitator superfamily
C3E78_05725	ENOG4105C9K	Endothelin-converting enzyme 1
C3E78_05765	ENOG4108MKI	Glycosyl transferase, family 2
C3E78_05775	ENOG4105CZN	Potassium uptake protein
C3E78_05780	ENOG4107ZYR	domain protein
C3E78_05790	ENOG4105D4Y	metalloprotease
C3E78_05805	ENOG4105C8T	Leucyl-tRNA synthetase
C3E78_05810	ENOG4105EPR	degv family
C3E78_05815	ENOG4105KQC	Competence protein
C3E78_05820	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
C3E78_05830	ENOG4105EYH	Exonuclease
C3E78_05845	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
C3E78_05850	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
C3E78_05860	ENOG4108IQE	Amp-dependent synthetase and ligase
C3E78_05885	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
C3E78_05890	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
C3E78_05895	ENOG4107YU2	histidine triad (hIT) protein
C3E78_05905	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
C3E78_05920	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
C3E78_05935	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
C3E78_05945	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C3E78_05975	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C3E78_05990	ENOG4105RHY	Pfam:UPF0157
C3E78_05995	ENOG4105CHF	Glutathione S-transferase
C3E78_06005	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
C3E78_06015	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
C3E78_06025	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
C3E78_06030	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
C3E78_06035	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
C3E78_06045	ENOG4105C26	Dehydrogenase
C3E78_06065	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
C3E78_06070	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
C3E78_06080	ENOG4108JU3	Alkyl hydroperoxide reductase
C3E78_06105	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
C3E78_06110	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
C3E78_06140	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
C3E78_06155	ENOG41069M3	Transcriptional regulator
C3E78_06160	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C3E78_06165	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C3E78_06180	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
C3E78_06185	ENOG4105C28	cystathionine
C3E78_06190	ENOG4105CPF	Cell wall formation (By similarity)
C3E78_06215	ENOG4105VB9	50S ribosomal protein l28
C3E78_06220	ENOG4105DP4	dak2 domain fusion protein ylov
C3E78_06230	ENOG4106H78	methyltransferase
C3E78_06235	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
C3E78_06240	ENOG4108KPJ	rna polymerase sigma factor
C3E78_06250	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C3E78_06260	ENOG41084BZ	50S ribosomal protein L32
C3E78_06265	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
C3E78_06270	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
C3E78_06280	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
C3E78_06300	ENOG4105K6H	D-cysteine desulfhydrase
C3E78_06305	ENOG4107RSM	transcriptional regulator
C3E78_06310	ENOG4105DTD	Dehydrogenase
C3E78_06325	ENOG4107W19	lmbE family
C3E78_06370	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
C3E78_06415	ENOG4105BZU	Histidine kinase
C3E78_06420	ENOG4108WQH	regulatoR
C3E78_06430	ENOG4105C7K	acetolactate synthase
C3E78_06445	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C3E78_06450	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C3E78_06455	ENOG4105CPC	Aldo Keto reductase
C3E78_06460	ENOG4105EGD	dinuclear metal center protein, YbgI family
C3E78_06470	ENOG4105CVJ	phosphoglycerate mutase
C3E78_06475	ENOG4107XFJ	UPF0246 protein
C3E78_06515	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
C3E78_06520	ENOG4105C4K	Nad synthetase
C3E78_06535	ENOG4105CHP	RNA polymerase
C3E78_06545	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
C3E78_06555	ENOG4105KIU	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
C3E78_06575	ENOG4105EJ2	Transcriptional regulator
C3E78_06590	ENOG4105WN5	stage II sporulation protein
C3E78_06615	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
C3E78_06625	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
C3E78_06670	ENOG4105ECR	NmrA family
C3E78_06710	ENOG4105CIS	alcohol dehydrogenase
C3E78_06725	ENOG4105KK4	UPF0060 membrane protein
C3E78_06735	ENOG4105EYF	MMPL domain protein
C3E78_06750	ENOG4105EYF	MMPL domain protein
C3E78_06755	ENOG4105BZU	Histidine kinase
C3E78_06760	ENOG4105WH1	Two component transcriptional regulator luxr family
C3E78_06790	ENOG4105VPX	protein, conserved in bacteria
C3E78_06795	ENOG4105C5F	glutamine synthetase
C3E78_06810	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
C3E78_06815	ENOG4105BZU	Histidine kinase
C3E78_06820	ENOG4105WH1	Two component transcriptional regulator luxr family
C3E78_06825	ENOG4108IUX	(ABC) transporter
C3E78_06835	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
C3E78_06860	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
C3E78_06895	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
C3E78_06900	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
C3E78_06920	ENOG4105D0M	Protease HtpX homolog
C3E78_06930	ENOG4105XT2	Transcriptional regulator
C3E78_06950	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
C3E78_06955	ENOG4105BZ9	Cytochrome C oxidase, subunit I
C3E78_06960	ENOG4105MCD	Part of cytochrome c oxidase, its function is
C3E78_06970	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
C3E78_06975	ENOG4107EUI	c reductase, iron-sulfur
C3E78_06980	ENOG4107UDY	cytochrome C
C3E78_06985	ENOG4105CCU	oxidase (Subunit III)
C3E78_06995	ENOG4107S1N	anthranilate phosphoribosyltransferase
C3E78_07015	ENOG4107SN7	NLP P60 protein
C3E78_07025	ENOG4108IQE	Amp-dependent synthetase and ligase
C3E78_07040	ENOG4105DKQ	ROK family
C3E78_07045	ENOG4105DKQ	ROK family
C3E78_07060	ENOG4105CTQ	phosphohexokinase
C3E78_07070	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
C3E78_07090	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
C3E78_07095	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
C3E78_07105	ENOG4108V6E	Cell division protein mraZ
C3E78_07110	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
C3E78_07120	ENOG4105CJN	penicillin-binding protein
C3E78_07125	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
C3E78_07135	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
C3E78_07140	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
C3E78_07150	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
C3E78_07155	ENOG4105DFU	Cell wall formation (By similarity)
C3E78_07165	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
C3E78_07170	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
C3E78_07175	ENOG4105DFA	alanine racemase domain protein
C3E78_07180	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
C3E78_07195	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
C3E78_07200	ENOG4105NHS	Transcriptional regulator, TraR DksA family
C3E78_07240	ENOG4105C0B	DNA polymerase III (alpha subunit)
C3E78_07250	ENOG4108Z66	YbaK ebsC protein
C3E78_07255	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
C3E78_07260	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C3E78_07265	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
C3E78_07270	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
C3E78_07280	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
C3E78_07290	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
C3E78_07295	ENOG4105BZ1	(ABC) transporter
C3E78_07300	ENOG4105BZ1	(ABC) transporter
C3E78_07305	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
C3E78_07320	ENOG4105W8D	rdd domain containing protein
C3E78_07330	ENOG4105DK0	Indole-3-glycerol phosphate synthase
C3E78_07335	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
C3E78_07340	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
C3E78_07345	ENOG4107TBN	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
C3E78_07365	ENOG4105CBC	glutamate synthase
C3E78_07375	ENOG4105CA9	Pyruvate kinase
C3E78_07400	ENOG4108IV0	ABC, transporter
C3E78_07405	ENOG4105C0Z	ABC transporter
C3E78_07415	ENOG4105C32	Amino acid ABC transporter (Permease)
C3E78_07420	ENOG4108UQV	Membrane
C3E78_07450	ENOG4105DFM	M18 family aminopeptidase
C3E78_07455	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
C3E78_07470	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
C3E78_07475	ENOG4105I8R	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C3E78_07485	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C3E78_07535	ENOG4105EXC	Acyl-transferase
C3E78_07545	ENOG4107UWP	Major facilitator superfamily MFS_1
C3E78_07555	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C3E78_07575	ENOG4107W53	thymidine kinase
C3E78_07585	ENOG4105EN6	Membrane
C3E78_07590	ENOG4105C26	Dehydrogenase
C3E78_07600	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
C3E78_07625	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
C3E78_07650	ENOG4107VEG	TrkA-N domain protein
C3E78_07655	ENOG4105C0X	amino acid
C3E78_07660	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C3E78_07680	ENOG4107QM5	aconitate hydratase
C3E78_07690	ENOG4105DFW	ABC transporter
C3E78_07695	ENOG4105C2J	ABC transporter
C3E78_07700	ENOG4107RNG	ABC transporter
C3E78_07715	ENOG4105D82	Glutamate dehydrogenase
C3E78_07730	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
C3E78_07740	ENOG4105C5F	glutamine synthetase
C3E78_07775	ENOG4105VMP	Transcriptional regulator
C3E78_07780	ENOG4105CNG	UPF0061 protein
C3E78_07805	ENOG4105CKU	formyltetrahydrofolate synthetase
C3E78_07820	ENOG4108IG5	Transcriptional regulator
C3E78_07825	ENOG4105CPC	Aldo Keto reductase
C3E78_07930	ENOG4105BZU	Histidine kinase
C3E78_07935	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
C3E78_07950	ENOG4105BZU	Histidine kinase
C3E78_07955	ENOG4105WH1	Two component transcriptional regulator luxr family
C3E78_07970	ENOG41066YJ	Beta-lactamase
C3E78_08055	ENOG41066F8	ROK family
C3E78_08080	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
C3E78_08090	ENOG4105C29	acyl-CoA thioesterase
C3E78_08100	ENOG4105CHR	reductase
C3E78_08105	ENOG4105CHU	acetyl-coa acetyltransferase
C3E78_08115	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
C3E78_08135	ENOG4107RY6	amino acid
C3E78_08185	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
C3E78_08190	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
C3E78_08195	ENOG4105CKW	Inner membrane protein yedI
C3E78_08200	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
C3E78_08205	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
C3E78_08215	ENOG4105CIE	May be required for sporulation (By similarity)
C3E78_08220	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
C3E78_08225	ENOG4105BZA	Phosphoglycerate kinase
C3E78_08230	ENOG4105CP7	Triose-phosphate isomerase
C3E78_08245	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
C3E78_08260	ENOG4105C89	phosphohexose isomerase
C3E78_08265	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
C3E78_08275	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
C3E78_08305	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
C3E78_08310	ENOG4105G9B	Transcriptional regulator
C3E78_08320	ENOG4105CHR	reductase
C3E78_08365	ENOG4105DQE	DNA ligase
C3E78_08395	ENOG4105C3K	feS assembly ATPase SufC
C3E78_08400	ENOG4105C9B	Cysteine desulfurase
C3E78_08405	ENOG4108UNV	SUF system FeS assembly protein, NifU family
C3E78_08410	ENOG4105VG1	fes assembly suf system protein
C3E78_08415	ENOG4105C5H	ABC transporter
C3E78_08425	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C3E78_08440	ENOG4105WKW	Pfam:DUF1458
C3E78_08450	ENOG4105YVS	arsR family transcriptional regulator
C3E78_08455	ENOG4105EAC	phosphoserine phosphatase
C3E78_08460	ENOG4105DKW	ABC transporter
C3E78_08480	ENOG4108V1U	phospholipid-binding protein
C3E78_08495	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
C3E78_08500	ENOG4105C1G	acyl-Coa dehydrogenase
C3E78_08505	ENOG4105C1G	acyl-Coa dehydrogenase
C3E78_08510	ENOG41067TZ	transcriptional regulator, MarR family
C3E78_08525	ENOG41081K0	peptidylprolyl cis-trans isomerase
C3E78_08530	ENOG4105CQ7	ATP-dependent helicase
C3E78_08545	ENOG4106BRA	Membrane
C3E78_08575	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C3E78_08595	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
C3E78_08600	ENOG4108IND	Tetr family transcriptional regulator
C3E78_08620	ENOG4108M15	ABC transporter
C3E78_08645	ENOG4105CSV	Glutaminase
C3E78_08655	ENOG4105E2A	Dehydrogenase
C3E78_08670	ENOG4105XEA	Tetr family transcriptional regulator
C3E78_08675	ENOG4105EYF	MMPL domain protein
C3E78_08680	ENOG4105WH1	Two component transcriptional regulator luxr family
C3E78_08690	ENOG4105CHR	reductase
C3E78_08705	ENOG41060BG	Tetr family transcriptional regulator
C3E78_08715	ENOG4107Z6X	Transcriptional regulator
C3E78_08730	ENOG41088YS	Glycosyl transferase (Group 1
C3E78_08735	ENOG4105CMR	udp-glucose 4-epimerase
C3E78_08750	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
C3E78_08755	ENOG4107VWK	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
C3E78_08820	ENOG4105H3G	oxidoreductase
C3E78_08825	ENOG4105ES4	Nitrilase
C3E78_08830	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
C3E78_08865	ENOG4107R13	MMPL domain protein
C3E78_08885	ENOG4105BZU	Histidine kinase
C3E78_08890	ENOG4107X2D	transcriptional regulator, merr family
C3E78_08895	ENOG4105E0A	ABC, transporter
C3E78_08900	ENOG4105EHG	Permease protein
C3E78_08910	ENOG4105E1F	short-chain dehydrogenase reductase
C3E78_08940	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
C3E78_08960	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C3E78_08970	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
C3E78_08975	ENOG4105KHC	sulfurtransferase
C3E78_08985	ENOG4108YZ9	Urea amidohydrolase subunit gamma
C3E78_09000	ENOG4105CQM	Urea amidohydrolase subunit alpha
C3E78_09005	ENOG4107YEM	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
C3E78_09010	ENOG4107S16	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
C3E78_09015	ENOG4105ICD	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
C3E78_09020	ENOG4105D9G	High-affinity
C3E78_09030	ENOG41083TI	Protein CrcB homolog
C3E78_09035	ENOG4107JBM	CrcB-like protein
C3E78_09040	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
C3E78_09060	ENOG4105DBV	ornithine carbamoyltransferase
C3E78_09065	ENOG4105CEU	Arginine dihydrolase
C3E78_09070	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
C3E78_09090	ENOG4105VN1	Heat shock protein
C3E78_09110	ENOG4105EET	magnesium chelatase
C3E78_09115	ENOG4107KWJ	von Willebrand factor, type A
C3E78_09130	ENOG4105EW6	flavin reductase domain protein, FMN-binding
C3E78_09180	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
C3E78_09190	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
C3E78_09215	ENOG4108FN7	Aldo keto reductase
C3E78_09220	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
C3E78_09225	ENOG4105D7N	magnesium and cobalt transport protein CorA
C3E78_09230	ENOG4105C8N	cysteinyl-tRNA synthetase
C3E78_09260	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
C3E78_09275	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
C3E78_09285	ENOG4108594	Permease of the drug metabolite transporter
C3E78_09295	ENOG4105E5F	proteasome
C3E78_09300	ENOG4105E0A	ABC, transporter
C3E78_09305	ENOG4105TVJ	transport system, permease
C3E78_09310	ENOG4105DQ5	transport system permease protein
C3E78_09325	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
C3E78_09330	ENOG4105F7N	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
C3E78_09335	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
C3E78_09360	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
C3E78_09375	ENOG4105HFS	5'-3' exonuclease
C3E78_09395	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
C3E78_09400	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
C3E78_09405	ENOG4105Q70	
C3E78_09420	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
C3E78_09425	ENOG4107T8T	UPF0173 metal-dependent hydrolase
C3E78_09470	ENOG4105D9U	N-acetyltransferase
C3E78_09475	ENOG4108WUH	Transcriptional regulator, TetR family
C3E78_09480	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C3E78_09495	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
C3E78_09505	ENOG4105EMU	Dehydrogenase
C3E78_09520	ENOG4106NZI	LysR family Transcriptional regulator
C3E78_09525	ENOG4105CRK	lysyL-tRNA synthetase
C3E78_09545	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C3E78_09570	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
C3E78_09575	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
C3E78_09590	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
C3E78_09625	ENOG4105C1G	acyl-Coa dehydrogenase
C3E78_09630	ENOG4105K6V	RNA polymerase
C3E78_09635	ENOG4105RNG	membrane
C3E78_09650	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C3E78_09725	ENOG4105C8Y	Acetylornithine aminotransferase
C3E78_09750	ENOG4105DKW	ABC transporter
C3E78_09760	ENOG4105WQ3	Rna-binding protein
C3E78_09770	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
C3E78_09775	ENOG4108URH	decarboxylase
C3E78_09800	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
C3E78_09845	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
C3E78_09855	ENOG4105CAT	Cytidine monophosphate kinase
C3E78_09870	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
C3E78_09875	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
C3E78_09900	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
C3E78_09915	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
C3E78_09920	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
C3E78_09935	ENOG4105DSU	hydrolase
C3E78_09965	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
C3E78_09970	ENOG4105SHT	UspA domain-containing protein
C3E78_09980	ENOG4105SHT	UspA domain-containing protein
C3E78_10000	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
C3E78_10005	ENOG4108V9W	transcriptional regulatory protein
C3E78_10010	ENOG4108VX5	3-methyladenine DNA glycosylase
C3E78_10015	ENOG4108ZR3	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)
C3E78_10020	ENOG4105CH7	arginosuccinase
C3E78_10025	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
C3E78_10030	ENOG4105DBV	ornithine carbamoyltransferase
C3E78_10035	ENOG4105C8Y	Acetylornithine aminotransferase
C3E78_10040	ENOG4105CAS	nag kinase
C3E78_10045	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
C3E78_10050	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
C3E78_10055	ENOG4105CDH	Citrulline--aspartate ligase
C3E78_10065	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
C3E78_10070	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
C3E78_10075	ENOG4105BZU	Histidine kinase
C3E78_10080	ENOG4108RWN	rrna methyltransferase
C3E78_10085	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
C3E78_10090	ENOG41084BS	50S ribosomal protein L35
C3E78_10095	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
C3E78_10120	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
C3E78_10125	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
C3E78_10130	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
C3E78_10135	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
C3E78_10150	ENOG4105DJV	ribulose-phosphate 3-epimerase
C3E78_10165	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
C3E78_10175	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
C3E78_10185	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
C3E78_10190	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
C3E78_10205	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
C3E78_10210	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
C3E78_10215	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
C3E78_10220	ENOG4105CD3	dihydroorotase
C3E78_10225	ENOG4105CXT	aspartate transcarbamylase
C3E78_10235	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
C3E78_10240	ENOG410803B	Involved in the transcription termination process (By similarity)
C3E78_10245	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
C3E78_10250	ENOG4105DC7	peptidase M24
C3E78_10255	ENOG4105D49	3-dehydroquinate synthase
C3E78_10260	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
C3E78_10265	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
C3E78_10285	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
C3E78_10290	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
C3E78_10310	ENOG4105C9M	aspartyl-trna synthetase
C3E78_10315	ENOG4105CUT	histidyl-tRNA synthetase
C3E78_10325	ENOG4105C99	atpase involved in dna repair
C3E78_10335	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
C3E78_10340	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
C3E78_10345	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C3E78_10350	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C3E78_10355	ENOG4105ZCJ	preprotein translocase subunit yajC
C3E78_10360	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
C3E78_10365	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
C3E78_10370	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
C3E78_10375	ENOG4105CDY	transcriptional regulatory protein
C3E78_10380	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
C3E78_10385	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
C3E78_10395	ENOG4105URP	P-aminobenzoate N-oxygenase AurF
C3E78_10400	ENOG4105CHH	sulfate transporter
C3E78_10405	ENOG4108Z6Z	Transcriptional regulator
C3E78_10410	ENOG4108VTU	Cdp-alcohol phosphatidyltransferase
C3E78_10420	ENOG4105C22	threonyL-tRNA synthetase
C3E78_10425	ENOG4105WH1	Two component transcriptional regulator luxr family
C3E78_10445	ENOG4105F95	Monooxygenase
C3E78_10465	ENOG4105CIG	ABC transporter
C3E78_10480	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C3E78_10510	ENOG4107QN2	dihydrolipoyl dehydrogenase
C3E78_10540	ENOG4107Z5F	Aminotransferase class IV
C3E78_10575	ENOG4105CSU	acyl-Coa dehydrogenase
C3E78_10605	ENOG4108KK1	membrane protein AbrB duplication
C3E78_10610	ENOG4105CSR	polyphosphate kinase 2
C3E78_10615	ENOG4105WH1	Two component transcriptional regulator luxr family
C3E78_10630	ENOG4105E0X	reductase
C3E78_10635	ENOG4107JTW	chlorite dismutase
C3E78_10640	ENOG4105C1Q	protoporphyrinogen oxidase
C3E78_10645	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
C3E78_10660	ENOG4105EKT	)-iron permease
C3E78_10670	ENOG4107SET	aldo keto reductase
C3E78_10680	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C3E78_10730	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
C3E78_10745	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
C3E78_10755	ENOG4105P52	geranylgeranyl reductase
C3E78_10775	ENOG4105BZU	Histidine kinase
C3E78_10795	ENOG4105DXB	Major Facilitator superfamily
C3E78_10800	ENOG4107G87	m6 family metalloprotease domain protein
C3E78_10810	ENOG4105VEQ	Cold shock protein
C3E78_10825	ENOG41080RH	Thioredoxin
C3E78_10865	ENOG4105C0D	helicase
C3E78_10910	ENOG4105D9P	serine threonine protein kinase
C3E78_10930	ENOG4105EE1	crotonyl-CoA reductase
C3E78_10940	ENOG4105C0D	helicase
C3E78_10945	ENOG4105EMU	Dehydrogenase
C3E78_10955	ENOG4105C7H	Helicase, RecD TraA family
C3E78_10960	ENOG4107QKA	exodeoxyribonuclease V beta
C3E78_10965	ENOG4105DSY	exodeoxyribonuclease V, gamma
C3E78_10985	ENOG4105DEN	Luciferase family
C3E78_10995	ENOG4105C37	(CBS) domain
C3E78_11000	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C3E78_11005	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
C3E78_11015	ENOG4105Y3U	Transglycosylase-associated protein
C3E78_11020	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
C3E78_11030	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C3E78_11040	ENOG4107S2Z	UPF0761 membrane protein
C3E78_11045	ENOG4105CHR	reductase
C3E78_11050	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
C3E78_11075	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
C3E78_11080	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
C3E78_11085	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
C3E78_11110	ENOG4105EYF	MMPL domain protein
C3E78_11125	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
C3E78_11185	ENOG4105KC9	Modulates RecA activity (By similarity)
C3E78_11190	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
C3E78_11200	ENOG4105ETE	Transcriptional regulator (LacI family
C3E78_11210	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
C3E78_11225	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C3E78_11240	ENOG4105CEV	competence damage-inducible protein
C3E78_11255	ENOG4107QZI	cell division protein FtsK
C3E78_11265	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
C3E78_11280	ENOG4105CN5	Metallo-Beta-Lactamase
C3E78_11285	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C3E78_11315	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
C3E78_11340	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
C3E78_11380	ENOG4105GR3	Histidine kinase
C3E78_11405	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
C3E78_11410	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
C3E78_11415	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
C3E78_11430	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
C3E78_11445	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
C3E78_11465	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
C3E78_11470	ENOG4105DZP	Membrane-associated zinc metalloprotease
C3E78_11485	ENOG4105CJ1	ABC, transporter
C3E78_11490	ENOG4105BZU	Histidine kinase
C3E78_11495	ENOG4105WH1	Two component transcriptional regulator luxr family
C3E78_11515	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
C3E78_11520	ENOG4105D38	putrescine abc transporter
C3E78_11525	ENOG4105F38	ABC transporter, permease
C3E78_11530	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C3E78_11560	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
C3E78_11575	ENOG4105NPQ	Pfam:DUF403
C3E78_11590	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
C3E78_11595	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
C3E78_11600	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
C3E78_11605	ENOG4105CE9	30S ribosomal protein S2
C3E78_11610	ENOG4105E4C	Lytic transglycosylase catalytic
C3E78_11630	ENOG4105C0P	Mg chelatase subunit ChlI
C3E78_11635	ENOG41080R2	UPF0102 protein
C3E78_11640	ENOG4108374	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
C3E78_11650	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C3E78_11665	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
C3E78_11675	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
C3E78_11680	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
C3E78_11685	ENOG41082KU	UPF0109 protein
C3E78_11690	ENOG4105K5M	30s ribosomal protein S16
C3E78_11705	ENOG4105K89	arsenate reductase
C3E78_11720	ENOG4105C6Z	Gluconate
C3E78_11725	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
C3E78_11735	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
C3E78_11755	ENOG4108JJ8	(ABC) transporter
C3E78_11760	ENOG4108JJ9	ABC, transporter
C3E78_11765	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
C3E78_11770	ENOG4105C4M	(Ubiquinol oxidase) subunit I
C3E78_11815	ENOG4105C2W	permease
C3E78_11830	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
C3E78_11840	ENOG4105DIK	(ABC) transporter
C3E78_11905	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
C3E78_11915	ENOG4108IJ0	Aspartate ammonia-lyase
C3E78_11920	ENOG4105CM2	brancheD-chain amino acid aminotransferase
C3E78_11925	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
C3E78_11955	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
C3E78_11960	ENOG4108ZP8	Acetolactate synthase small subunit
C3E78_11990	ENOG4105C01	Dihydroxy-acid dehydratase
C3E78_12020	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
C3E78_12030	ENOG4105BZU	Histidine kinase
C3E78_12035	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C3E78_12040	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C3E78_12045	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C3E78_12050	ENOG4105CPT	Alpha beta hydrolase
C3E78_12065	ENOG4108W1A	pseudouridine synthase
C3E78_12085	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
C3E78_12095	ENOG4107QI6	Cysteine desulfurase
C3E78_12100	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
C3E78_12110	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
C3E78_12120	ENOG4107RYT	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
C3E78_12135	ENOG4105BZU	Histidine kinase
C3E78_12140	ENOG4105WH1	Two component transcriptional regulator luxr family
C3E78_12150	ENOG4105C0B	DNA polymerase III (alpha subunit)
C3E78_12170	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C3E78_12180	ENOG4108J59	Extracellular solute-binding protein, family 5
C3E78_12190	ENOG4105BZJ	Electron transfer flavoprotein
C3E78_12210	ENOG4108YRB	methyltransferase
C3E78_12225	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
C3E78_12230	ENOG41070F3	Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity)
C3E78_12235	ENOG4105CG3	alpha amylase, catalytic region
C3E78_12240	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
C3E78_12355	ENOG4105CHU	acetyl-coa acetyltransferase
C3E78_12385	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C3E78_12395	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
C3E78_12400	ENOG4107YEV	ferritin
C3E78_12405	ENOG4105RFZ	Methylmalonyl-coA mutase
C3E78_12425	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
C3E78_12430	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
C3E78_12435	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
C3E78_12440	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
C3E78_12445	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C3E78_12450	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
C3E78_12455	ENOG4106DE0	ATP synthase
C3E78_12460	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
C3E78_12470	ENOG4105ESV	Glycosyl transferase, family 4
C3E78_12485	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C3E78_12490	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
C3E78_12495	ENOG4105VFB	Binds the 23S rRNA (By similarity)
C3E78_12510	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
C3E78_12515	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
C3E78_12520	ENOG4105D6E	homoserine dehydrogenase
C3E78_12545	ENOG4108Z4X	TRANSCRIPTIONal
C3E78_12555	ENOG4105C75	arginyL-tRNA synthetase
C3E78_12560	ENOG4105ETX	regulatoR
C3E78_12595	ENOG4108NNZ	chitinase
C3E78_12605	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
C3E78_12610	ENOG4105CB2	alcohol dehydrogenase
C3E78_12720	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C3E78_12725	ENOG4105BZU	Histidine kinase
C3E78_12780	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
C3E78_12785	ENOG4105T0Z	Conserved Protein
C3E78_12790	ENOG4105WH1	Two component transcriptional regulator luxr family
C3E78_12795	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
C3E78_12800	ENOG4105MJ2	Competence protein
C3E78_12810	ENOG4105BZU	Histidine kinase
C3E78_12815	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C3E78_12820	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
C3E78_12845	ENOG4105W49	UPF0434 protein
C3E78_12875	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
C3E78_12880	ENOG4105EIH	LPPG Fo 2-phospho-L-lactate transferase
C3E78_12895	ENOG4105EY8	ABC transporter
C3E78_12900	ENOG4108KGH	TRANSCRIPTIONal
C3E78_12910	ENOG4108KGH	TRANSCRIPTIONal
C3E78_12915	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
C3E78_12925	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
C3E78_12945	ENOG4108Z4U	Ferredoxin
C3E78_12970	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
C3E78_12990	ENOG4105QE3	oxidoreductase
C3E78_12995	ENOG4105C09	Bile acid
C3E78_13030	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C3E78_13040	ENOG4108IG5	Transcriptional regulator
C3E78_13050	ENOG4105C57	major facilitator superfamily
C3E78_13070	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
C3E78_13090	ENOG4105D5T	phosphonate abc transporter
C3E78_13115	ENOG4107GJV	short-chain dehydrogenase reductase
C3E78_13130	ENOG4105C3G	gtp-binding protein
C3E78_13160	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
C3E78_13165	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
C3E78_13175	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C3E78_13180	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C3E78_13235	ENOG4105C9Q	fumarate hydratase class II
C3E78_13265	ENOG4108IAB	Phoh family
C3E78_13270	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
C3E78_13280	ENOG4105C7Z	Conserved Protein
C3E78_13305	ENOG4105T1M	mycothiol conjugate amidase mca
C3E78_13315	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
C3E78_13320	ENOG4105C7B	Threonine dehydratase
C3E78_13370	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
C3E78_13375	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C3E78_13400	ENOG4105R3A	Nitrate reductase
C3E78_13405	ENOG4108IUE	nitrate reductase beta subunit
C3E78_13420	ENOG4105JAB	phenazine biosynthesis protein, phzf family
C3E78_13440	ENOG41062KD	Inherit from COG: ketosteroid isomerase-like protein
C3E78_13470	ENOG4105CSV	Glutaminase
C3E78_13490	ENOG4105CHR	reductase
C3E78_13515	ENOG4105DJZ	UPF0182 protein
C3E78_13525	ENOG41063PX	domain protein
C3E78_13530	ENOG4108ZAF	Molybdopterin
C3E78_13555	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
C3E78_13575	ENOG4105C4R	Atp-dependent dna helicase
C3E78_13610	ENOG4105C1J	atp-dependent rna helicase
C3E78_13620	ENOG4107QJE	Chromosome Partitioning Protein
C3E78_13625	ENOG4105EMU	Dehydrogenase
C3E78_13660	ENOG4108KEZ	Dehydrogenase
C3E78_13665	ENOG4105C57	major facilitator superfamily
C3E78_13680	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
C3E78_13710	ENOG4105G9B	Transcriptional regulator
C3E78_13725	ENOG4108ZM9	phosphoglycerate mutase
C3E78_13730	ENOG4105DJG	MaoC domain protein dehydratase
C3E78_13740	ENOG4105C1G	acyl-Coa dehydrogenase
C3E78_13750	ENOG4105ECP	epimerase
C3E78_13780	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C3E78_13795	ENOG4105DQ4	alcohol dehydrogenase
C3E78_13800	ENOG4105CJW	magnesium transporter
C3E78_13810	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
C3E78_13815	ENOG4105C5H	ABC transporter
C3E78_13825	ENOG410630M	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
C3E78_13840	ENOG4107ZBN	O-methyltransferase
C3E78_13855	ENOG4108UKI	Enoyl-CoA hydratase
C3E78_13865	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C3E78_13870	ENOG4108URH	decarboxylase
C3E78_13875	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
C3E78_13910	ENOG4108QER	Adenylate cyclase
C3E78_13925	ENOG4105D8K	carboxyl transferase
C3E78_13940	ENOG4107WR6	Maf-like protein
C3E78_13950	ENOG4105C1G	acyl-Coa dehydrogenase
C3E78_13955	ENOG4108JIK	carboxylase
C3E78_13995	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
C3E78_14040	ENOG4105CHR	reductase
C3E78_14045	ENOG4105E39	Enoyl-CoA hydratase
C3E78_14060	ENOG4106517	Short-chain dehydrogenase reductase Sdr
C3E78_14070	ENOG4105E39	Enoyl-CoA hydratase
C3E78_14075	ENOG4105CC9	acyl-Coa dehydrogenase
C3E78_14080	ENOG4105D2B	acyl-CoA dehydrogenase
C3E78_14085	ENOG4105CD5	CoA-binding domain protein
C3E78_14095	ENOG4108IV0	ABC, transporter
C3E78_14100	ENOG4105C0Z	ABC transporter
C3E78_14115	ENOG41069HH	4-oxalocrotonate tautomerase
C3E78_14120	ENOG4105FDP	GntR family transcriptional regulator
C3E78_14125	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
C3E78_14130	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
C3E78_14145	ENOG4106A3M	Cytochrome p-450
C3E78_14160	ENOG4105UIB	(ABC) transporter
C3E78_14165	ENOG4108JQ9	ABC transporter
C3E78_14170	ENOG4105DIH	basic membrane
C3E78_14175	ENOG4107RM1	amidohydrolase
C3E78_14190	ENOG4105E33	succinate dehydrogenase
C3E78_14215	ENOG4105C31	Tryptophanyl-tRNA synthetase
C3E78_14220	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
C3E78_14225	ENOG4105CQC	Prephenate dehydratase
C3E78_14245	ENOG4105CIY	formyltetrahydrofolate deformylase
C3E78_14250	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
C3E78_14255	ENOG4108I5D	sulfate abc transporter
C3E78_14260	ENOG4105ECW	sulfate abc transporter
C3E78_14265	ENOG4108IJ6	ABC transporter
C3E78_14270	ENOG4105F27	Major Facilitator
C3E78_14280	ENOG4105E9K	Isocitrate dehydrogenase
C3E78_14285	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
C3E78_14295	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
C3E78_14310	ENOG4105DC1	bifunctional purine biosynthesis protein purh
C3E78_14335	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
C3E78_14360	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
C3E78_14375	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
C3E78_14400	ENOG4105WH1	Two component transcriptional regulator luxr family
C3E78_14425	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
C3E78_14435	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
C3E78_14440	ENOG4105BZP	glycoside hydrolase 15-related
C3E78_14445	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
C3E78_14470	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C3E78_14500	ENOG4105DBE	peroxidase
C3E78_14505	ENOG410650H	(LipO)protein
C3E78_14520	ENOG4107QVP	Dehydrogenase
C3E78_14530	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C3E78_14545	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
C3E78_14550	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
C3E78_14555	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
C3E78_14570	ENOG4105E7W	lamb ycsf family protein
C3E78_14575	ENOG4105P4J	Allophanate hydrolase, subunit 1
C3E78_14585	ENOG4105D17	glycoside hydrolase, family 3 domain protein
C3E78_14590	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C3E78_14635	ENOG4108097	ATP-binding protein
C3E78_14645	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
C3E78_14655	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
C3E78_14660	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
C3E78_14665	ENOG4105CS9	pantothenic acid kinase
C3E78_14685	ENOG4105D9P	serine threonine protein kinase
C3E78_14690	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
C3E78_14695	ENOG4108UJD	30S ribosomal protein S9
C3E78_14700	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
C3E78_14710	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
C3E78_14715	ENOG4105KNA	-acetyltransferase
C3E78_14730	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
C3E78_14735	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
C3E78_14740	ENOG4108ZT0	50S ribosomal protein l17
C3E78_14745	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C3E78_14750	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
C3E78_14755	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
C3E78_14760	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C3E78_14765	ENOG41067V7	50S ribosomal protein L36
C3E78_14770	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
C3E78_14775	ENOG4105EW9	transcriptional regulator AsnC family
C3E78_14780	ENOG4105CIK	Amidinotransferase
C3E78_14800	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
C3E78_14810	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
C3E78_14815	ENOG410849U	50S ribosomal protein L30
C3E78_14820	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
C3E78_14825	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
C3E78_14830	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
C3E78_14835	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
C3E78_14840	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
C3E78_14845	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C3E78_14850	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
C3E78_14855	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
C3E78_14860	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
C3E78_14865	ENOG41082SA	50s ribosomal protein l29
C3E78_14870	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
C3E78_14875	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
C3E78_14880	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
C3E78_14885	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
C3E78_14890	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C3E78_14895	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
C3E78_14900	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
C3E78_14905	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
C3E78_14910	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
C3E78_14925	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
C3E78_14930	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
C3E78_14935	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
C3E78_14940	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
C3E78_14945	ENOG4105CQB	FAD linked oxidase domain protein
C3E78_14965	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
C3E78_14970	ENOG4108TGC	Acyltransferase
C3E78_14990	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C3E78_14995	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C3E78_15055	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
C3E78_15075	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
C3E78_15080	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
C3E78_15085	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
C3E78_15115	ENOG4107R4N	Cell wall formation (By similarity)
C3E78_15120	ENOG4105WDJ	50S ribosomal protein L33
C3E78_15140	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
C3E78_15150	ENOG4105CSV	Glutaminase
C3E78_15155	ENOG4105F8J	Adenylate Guanylate cyclase
C3E78_15195	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
C3E78_15205	ENOG4105F6J	Alpha beta hydrolase fold
C3E78_15230	ENOG4107QHE	Choloylglycine hydrolase
C3E78_15255	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
C3E78_15310	ENOG4108VGI	doxx family
C3E78_15335	ENOG4107HP6	Transcriptional regulator
C3E78_15350	ENOG4105E2A	Dehydrogenase
C3E78_15370	ENOG4105DMF	Dehydrogenase
C3E78_15375	ENOG4105KJM	monovalent cation h antiporter subunit g
C3E78_15390	ENOG4108JPZ	Monovalent cation H antiporter subunit D
C3E78_15395	ENOG4105MKQ	Monovalent cation H antiporter subunit C
C3E78_15400	ENOG4105D65	subunit l
C3E78_15435	ENOG4105XDV	
C3E78_15455	ENOG4108VPT	UPF0234 protein
C3E78_15460	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C3E78_15465	ENOG4105C8S	subunit m
C3E78_15475	ENOG41082X4	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C3E78_15485	ENOG4108M11	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C3E78_15500	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C3E78_15505	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C3E78_15510	ENOG4105EMU	Dehydrogenase
C3E78_15530	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C3E78_15540	ENOG4105D65	subunit l
C3E78_15545	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C3E78_15550	ENOG4105DF2	NADH dehydrogenase subunit j
C3E78_15555	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C3E78_15560	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
C3E78_15565	ENOG4108IEH	NADH dehydrogenase subunit g
C3E78_15570	ENOG4107QIZ	NADH dehydrogenase
C3E78_15580	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C3E78_15585	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C3E78_15590	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C3E78_15600	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
C3E78_15605	ENOG4105E4F	Isochorismate synthase
C3E78_15620	ENOG4107SM8	Adenylate Guanylate cyclase
C3E78_15635	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
C3E78_15640	ENOG4107TCW	O-succinylbenzoate synthase
C3E78_15695	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
C3E78_15705	ENOG4105CJ1	ABC, transporter
C3E78_15720	ENOG4105CRE	cytochrome C
C3E78_15730	ENOG4107QIV	Cytochrome c biogenesis protein
C3E78_15740	ENOG4108RH7	phosphoglycerate mutase
C3E78_15745	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
C3E78_15755	ENOG4105D52	delta-aminolevulinic acid dehydratase
C3E78_15770	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
C3E78_15775	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
C3E78_15785	ENOG4105CEY	Amp-dependent synthetase and ligase
C3E78_15790	ENOG4108RXW	HAD-superfamily subfamily IB hydrolase
C3E78_15825	ENOG4105DGU	Histone deacetylase
C3E78_15835	ENOG4105DHU	Bile acid
C3E78_15840	ENOG410829K	Lysine exporter protein (Lyse ygga)
C3E78_15845	ENOG4105EY0	Xylose isomerase domain protein TIM barrel
C3E78_15850	ENOG4107R33	ppx gppa phosphatase
C3E78_15855	ENOG4108JWX	
C3E78_15880	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
C3E78_15890	ENOG4105CEN	a g-specific adenine glycosylase
C3E78_15895	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C3E78_15900	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
C3E78_15905	ENOG4105CRK	lysyL-tRNA synthetase
C3E78_15910	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
C3E78_15915	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
C3E78_15920	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
C3E78_15945	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C3E78_15980	ENOG4105EUJ	GTP cyclohydrolase i
C3E78_15995	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
C3E78_16005	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
C3E78_16010	ENOG4105F0N	pyrophosphate phospho-hydrolase
C3E78_16030	ENOG4107RN6	Monooxygenase
C3E78_16085	ENOG4105EC2	ftsk spoIIIe
C3E78_16105	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
C3E78_16155	ENOG4107SET	aldo keto reductase
C3E78_16160	ENOG4105W1Y	Transcriptional regulator
C3E78_16165	ENOG4105CKK	Glycosyl transferase, family 2
C3E78_16175	ENOG4105C57	major facilitator superfamily
C3E78_16190	ENOG4105CUB	amino acid
C3E78_16215	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
C3E78_16235	ENOG4108ZHJ	Organic hydroperoxide resistance protein
C3E78_16255	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
C3E78_16265	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
C3E78_16270	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
C3E78_16275	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
C3E78_16280	ENOG4105CVJ	phosphoglycerate mutase
C3E78_16295	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
C3E78_16305	ENOG4108YZT	Adenosylcobinamide kinase
C3E78_16310	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
C3E78_16320	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
C3E78_16330	ENOG4105VEQ	Cold shock protein
C3E78_16340	ENOG4108JJB	ABC transporter
C3E78_16380	ENOG41090MY	MarR family Transcriptional regulator
C3E78_16385	ENOG4105D5P	Methylmalonyl-coA mutase
C3E78_16390	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
C3E78_16400	ENOG4105EF1	ribulokinase
C3E78_16405	ENOG4105ETE	Transcriptional regulator (LacI family
C3E78_16410	ENOG41062B0	ABC transporter, permease
C3E78_16415	ENOG4107R9N	ABC transporter
C3E78_16420	ENOG4105C2J	ABC transporter
C3E78_16425	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
C3E78_16440	ENOG4108UKI	Enoyl-CoA hydratase
C3E78_16445	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
C3E78_16455	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C3E78_16460	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
C3E78_16510	ENOG4105C1G	acyl-Coa dehydrogenase
C3E78_16520	ENOG4105C26	Dehydrogenase
C3E78_16525	ENOG4108FUF	Transcriptional regulator, IclR family
C3E78_16530	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
C3E78_16535	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
C3E78_16540	ENOG4105CEY	Amp-dependent synthetase and ligase
C3E78_16545	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
C3E78_16550	ENOG4105E39	Enoyl-CoA hydratase
C3E78_16570	ENOG4105CPQ	Dehydrogenase
C3E78_16580	ENOG4106HB6	Alpha beta hydrolase
C3E78_16595	ENOG4105CAY	ferredoxin--nadp reductase
C3E78_16605	ENOG4105CHR	reductase
C3E78_16620	ENOG4105C26	Dehydrogenase
C3E78_16650	ENOG4107HP6	Transcriptional regulator
C3E78_16655	ENOG4107HP6	Transcriptional regulator
C3E78_16675	ENOG4105C2J	ABC transporter
C3E78_16690	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
C3E78_16695	ENOG4105CNN	ABC, transporter
C3E78_16700	ENOG4105C2J	ABC transporter
C3E78_16705	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
C3E78_16710	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C3E78_16740	ENOG4105CPN	adenine deaminase
C3E78_16755	ENOG4105D5Q	Arginine ornithine antiporter
C3E78_16795	ENOG4108ZJI	phenylacetic acid degradation protein
C3E78_16800	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
C3E78_16805	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
C3E78_16810	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
C3E78_16815	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
C3E78_16820	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
C3E78_16850	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
C3E78_16890	ENOG4105CEY	Amp-dependent synthetase and ligase
C3E78_16900	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
C3E78_16920	ENOG4105KNI	merR family transcriptional Regulator
C3E78_16925	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
C3E78_16930	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C3E78_16935	ENOG4105CFG	Acts as a chaperone (By similarity)
C3E78_16950	ENOG4105EYF	MMPL domain protein
C3E78_16955	ENOG4108JGH	Tetr family transcriptional regulator
C3E78_16975	ENOG4105C72	UPF0176 protein
C3E78_17040	ENOG4108JJB	ABC transporter
C3E78_17045	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
C3E78_17050	ENOG4105CJP	fad dependent oxidoreductase
C3E78_17070	ENOG4105E5T	Major Facilitator Superfamily
C3E78_17075	ENOG4105DF6	Fe-S oxidoreductase
C3E78_17080	ENOG4105K5B	UPF0225 protein
C3E78_17090	ENOG4105CJ1	ABC, transporter
C3E78_17095	ENOG4107QKS	N-acylglucosamine 2-epimerase
C3E78_17100	ENOG4108KPW	sugar kinase
C3E78_17110	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
C3E78_17120	ENOG4105DHP	deoxycytidine triphosphate deaminase
C3E78_17130	ENOG4105I4A	GCN5-related N-acetyltransferase
C3E78_17165	ENOG4108KXV	response regulator
C3E78_17175	ENOG4107USC	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
C3E78_17185	ENOG4107SET	aldo keto reductase
C3E78_17195	ENOG4105BZU	Histidine kinase
C3E78_17205	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
C3E78_17210	ENOG4105JQN	Transcriptional regulator
C3E78_17220	ENOG4105CSU	acyl-Coa dehydrogenase
C3E78_17240	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
C3E78_17245	ENOG4105CPP	Dehydrogenase, E1 component
C3E78_17255	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C3E78_17260	ENOG4108UZ3	Transporter
C3E78_17265	ENOG41082T9	Membrane
C3E78_17270	ENOG4105KJF	protein tyrosine phosphatase
C3E78_17285	ENOG41062D9	Histidine kinase
C3E78_17290	ENOG4105C0H	protease
C3E78_17295	ENOG4107Y9U	Membrane
C3E78_17310	ENOG4107EFR	Flavocytochrome c
C3E78_17320	ENOG4108R85	Short chain dehydrogenase
C3E78_17325	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C3E78_17335	ENOG4105C26	Dehydrogenase
C3E78_17345	ENOG4105CNN	ABC, transporter
C3E78_17350	ENOG4105C2J	ABC transporter
C3E78_17375	ENOG4108UAU	isochorismatase
C3E78_17440	ENOG4105CDA	abc transporter atp-binding protein
C3E78_17450	ENOG4105E39	Enoyl-CoA hydratase
C3E78_17465	ENOG4107QX3	carboxylase
C3E78_17470	ENOG4105C1G	acyl-Coa dehydrogenase
C3E78_17485	ENOG4108RF4	Tetr family transcriptional regulator
C3E78_17515	ENOG4107YPT	transcriptional regulator
C3E78_17540	ENOG4105DWV	Homoserine O-trans-acetylase
C3E78_17600	ENOG4105CGU	Enoyl-CoA hydratase
C3E78_17605	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
C3E78_17620	ENOG4105CGD	Nad-dependent epimerase dehydratase
C3E78_17630	ENOG4105CUB	amino acid
C3E78_17660	ENOG4105E0A	ABC, transporter
C3E78_17665	ENOG4105TVJ	transport system, permease
C3E78_17670	ENOG4105DQ5	transport system permease protein
C3E78_17675	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C3E78_17680	ENOG4105CHU	acetyl-coa acetyltransferase
C3E78_17695	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
C3E78_17705	ENOG4105H3G	oxidoreductase
C3E78_17720	ENOG4105E5Q	amino acid AbC transporter
C3E78_17725	ENOG4105EAB	amino acid AbC transporter
C3E78_17735	ENOG4105U3E	Transcriptional regulator
C3E78_17750	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C3E78_17770	ENOG4108JQ1	Dehydrogenase
C3E78_17780	ENOG4105VPX	protein, conserved in bacteria
C3E78_17810	ENOG4105BZ1	(ABC) transporter
C3E78_17830	ENOG4107T5V	SNARE associated Golgi
C3E78_17840	ENOG4105CDU	Replicative dna helicase
C3E78_17845	ENOG4107R73	Mate efflux family protein
C3E78_17850	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
C3E78_17855	ENOG4105HJK	ABC transporter
C3E78_17860	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
C3E78_17865	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
C3E78_17875	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
C3E78_17890	ENOG4105CQ7	ATP-dependent helicase
C3E78_17895	ENOG4105CPC	Aldo Keto reductase
C3E78_17940	ENOG4105BZ4	penicillin-binding protein
C3E78_17950	ENOG4105CZA	synthase
C3E78_17965	ENOG4105C0Z	ABC transporter
C3E78_17970	ENOG4108IV0	ABC, transporter
C3E78_17980	ENOG4105CNN	ABC, transporter
C3E78_17990	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
C3E78_18010	ENOG4108DT4	serine threonine protein kinase
C3E78_18015	ENOG4105C3M	thioredoxin reductase
C3E78_18020	ENOG4105K63	Thioredoxin
C3E78_18030	ENOG4107QJE	Chromosome Partitioning Protein
C3E78_18035	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
C3E78_18045	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
C3E78_18050	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
C3E78_18055	ENOG4105XH8	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)