locus-tag	class	description
C6I20_00015	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
C6I20_00035	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
C6I20_00125	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C6I20_00245	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C6I20_00255	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
C6I20_00270	ENOG4105D5P	Methylmalonyl-coA mutase
C6I20_00280	ENOG4105C1G	acyl-Coa dehydrogenase
C6I20_00300	ENOG4105BZ1	(ABC) transporter
C6I20_00315	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
C6I20_00325	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
C6I20_00340	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
C6I20_00345	ENOG4108JJB	ABC transporter
C6I20_00360	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
C6I20_00370	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
C6I20_00375	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
C6I20_00380	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
C6I20_00485	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
C6I20_00490	ENOG4105CQ7	ATP-dependent helicase
C6I20_00505	ENOG4105C19	ABC transporter
C6I20_00510	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C6I20_00525	ENOG4105W1Y	Transcriptional regulator
C6I20_00530	ENOG4107SET	aldo keto reductase
C6I20_00560	ENOG4105F95	Monooxygenase
C6I20_00565	ENOG41062JF	Transcriptional regulator
C6I20_00570	ENOG4105F0N	pyrophosphate phospho-hydrolase
C6I20_00585	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
C6I20_00600	ENOG4105EUJ	GTP cyclohydrolase i
C6I20_00605	ENOG4105EEI	dihydropteroate synthase
C6I20_00635	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C6I20_00645	ENOG4105K64	Glycosyl transferase, family 2
C6I20_00655	ENOG4107QQT	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
C6I20_00660	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
C6I20_00665	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
C6I20_00670	ENOG4105CRK	lysyL-tRNA synthetase
C6I20_00675	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C6I20_00705	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
C6I20_00710	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
C6I20_00725	ENOG4108JWX	
C6I20_00730	ENOG4107R33	ppx gppa phosphatase
C6I20_00735	ENOG4105EY0	Xylose isomerase domain protein TIM barrel
C6I20_00740	ENOG410829K	Lysine exporter protein (Lyse ygga)
C6I20_00745	ENOG4105DHU	Bile acid
C6I20_00755	ENOG4105DGU	Histone deacetylase
C6I20_00790	ENOG4108RXW	HAD-superfamily subfamily IB hydrolase
C6I20_00795	ENOG4105CEY	Amp-dependent synthetase and ligase
C6I20_00805	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
C6I20_00810	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
C6I20_00815	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
C6I20_00825	ENOG4105D52	delta-aminolevulinic acid dehydratase
C6I20_00835	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
C6I20_00840	ENOG4108RH7	phosphoglycerate mutase
C6I20_00850	ENOG4107QIV	Cytochrome c biogenesis protein
C6I20_00860	ENOG4105CRE	cytochrome C
C6I20_00865	ENOG4105CJ1	ABC, transporter
C6I20_00915	ENOG4107TCW	O-succinylbenzoate synthase
C6I20_00920	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
C6I20_00940	ENOG4105E4F	Isochorismate synthase
C6I20_00945	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
C6I20_00950	ENOG4105D9G	High-affinity
C6I20_00960	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C6I20_00965	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C6I20_00970	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C6I20_00980	ENOG4107QIZ	NADH dehydrogenase
C6I20_00985	ENOG4108IEH	NADH dehydrogenase subunit g
C6I20_00990	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
C6I20_00995	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C6I20_01000	ENOG4105DF2	NADH dehydrogenase subunit j
C6I20_01005	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C6I20_01010	ENOG4105D65	subunit l
C6I20_01020	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C6I20_01040	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C6I20_01045	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C6I20_01050	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C6I20_01060	ENOG4108M11	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C6I20_01070	ENOG41082X4	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C6I20_01080	ENOG4105C8S	subunit m
C6I20_01085	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C6I20_01090	ENOG4108VPT	UPF0234 protein
C6I20_01165	ENOG4105C26	Dehydrogenase
C6I20_01175	ENOG41067HS	methyltransferase
C6I20_01180	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
C6I20_01185	ENOG4105VSH	4-oxalocrotonate tautomerase
C6I20_01190	ENOG4105WH1	Two component transcriptional regulator luxr family
C6I20_01195	ENOG4105BZU	Histidine kinase
C6I20_01205	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
C6I20_01220	ENOG4105WDJ	50S ribosomal protein L33
C6I20_01225	ENOG4107R4N	Cell wall formation (By similarity)
C6I20_01260	ENOG410683Z	Preprotein translocase SecE subunit
C6I20_01265	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
C6I20_01270	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
C6I20_01275	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
C6I20_01295	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
C6I20_01355	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C6I20_01360	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C6I20_01370	ENOG4108TGC	Acyltransferase
C6I20_01375	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
C6I20_01395	ENOG4105CQB	FAD linked oxidase domain protein
C6I20_01405	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
C6I20_01410	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
C6I20_01415	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
C6I20_01420	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
C6I20_01470	ENOG4105CY3	ABC transporter, permease
C6I20_01475	ENOG4105CY3	ABC transporter, permease
C6I20_01490	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
C6I20_01495	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
C6I20_01500	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
C6I20_01505	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C6I20_01510	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
C6I20_01515	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
C6I20_01520	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
C6I20_01525	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
C6I20_01530	ENOG41082SA	50s ribosomal protein l29
C6I20_01535	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
C6I20_01540	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
C6I20_01545	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
C6I20_01550	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C6I20_01555	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
C6I20_01560	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
C6I20_01565	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
C6I20_01570	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
C6I20_01575	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
C6I20_01580	ENOG410849U	50S ribosomal protein L30
C6I20_01585	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
C6I20_01595	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
C6I20_01610	ENOG4105CIK	Amidinotransferase
C6I20_01615	ENOG4105EW9	transcriptional regulator AsnC family
C6I20_01625	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
C6I20_01630	ENOG41067V7	50S ribosomal protein L36
C6I20_01635	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C6I20_01640	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
C6I20_01645	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
C6I20_01650	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C6I20_01655	ENOG4108ZT0	50S ribosomal protein l17
C6I20_01660	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
C6I20_01665	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
C6I20_01670	ENOG4105BZN	citrate synthase
C6I20_01675	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
C6I20_01680	ENOG4108UJD	30S ribosomal protein S9
C6I20_01685	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
C6I20_01695	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
C6I20_01700	ENOG4105CS9	pantothenic acid kinase
C6I20_01705	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
C6I20_01710	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
C6I20_01715	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
C6I20_01720	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
C6I20_01730	ENOG4108097	ATP-binding protein
C6I20_01765	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C6I20_01785	ENOG4105E7W	lamb ycsf family protein
C6I20_01795	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
C6I20_01800	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
C6I20_01815	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C6I20_01825	ENOG4107QVP	Dehydrogenase
C6I20_01840	ENOG410650H	(LipO)protein
C6I20_01845	ENOG4105DBE	peroxidase
C6I20_01855	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C6I20_01890	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
C6I20_01915	ENOG4105WH1	Two component transcriptional regulator luxr family
C6I20_01920	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
C6I20_01925	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
C6I20_01960	ENOG4105D74	hydrolase
C6I20_01965	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
C6I20_01990	ENOG4105DC1	bifunctional purine biosynthesis protein purh
C6I20_02000	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
C6I20_02010	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
C6I20_02015	ENOG4105CH6	catalase
C6I20_02025	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
C6I20_02030	ENOG4105E9K	Isocitrate dehydrogenase
C6I20_02040	ENOG4105F27	Major Facilitator
C6I20_02045	ENOG4108IJ6	ABC transporter
C6I20_02050	ENOG4105ECW	sulfate abc transporter
C6I20_02055	ENOG4108I5D	sulfate abc transporter
C6I20_02060	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
C6I20_02085	ENOG4105D9U	N-acetyltransferase
C6I20_02090	ENOG4105CQC	Prephenate dehydratase
C6I20_02095	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
C6I20_02100	ENOG4105C31	Tryptophanyl-tRNA synthetase
C6I20_02125	ENOG4105E33	succinate dehydrogenase
C6I20_02145	ENOG4107RM1	amidohydrolase
C6I20_02150	ENOG4105DIH	basic membrane
C6I20_02155	ENOG4108JQ9	ABC transporter
C6I20_02160	ENOG4105UIB	(ABC) transporter
C6I20_02175	ENOG4106A3M	Cytochrome p-450
C6I20_02190	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
C6I20_02195	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
C6I20_02200	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
C6I20_02210	ENOG4105C26	Dehydrogenase
C6I20_02215	ENOG4105C26	Dehydrogenase
C6I20_02220	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
C6I20_02225	ENOG4105CGH	5'-nucleotidase
C6I20_02230	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
C6I20_02270	ENOG4108JIK	carboxylase
C6I20_02275	ENOG4105C1G	acyl-Coa dehydrogenase
C6I20_02285	ENOG4107WR6	Maf-like protein
C6I20_02300	ENOG4105D8K	carboxyl transferase
C6I20_02315	ENOG4108QER	Adenylate cyclase
C6I20_02325	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
C6I20_02340	ENOG4105C1G	acyl-Coa dehydrogenase
C6I20_02345	ENOG4105FDR	Membrane
C6I20_02350	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
C6I20_02355	ENOG4105C1G	acyl-Coa dehydrogenase
C6I20_02365	ENOG4105CC9	acyl-Coa dehydrogenase
C6I20_02375	ENOG4108U0I	binding-protein-dependent transport systems inner membrane Component
C6I20_02380	ENOG4108IJ8	ABC transporter
C6I20_02385	ENOG4105WJV	Binding-protein-dependent transport systems, inner membrane component
C6I20_02395	ENOG4105C7K	acetolactate synthase
C6I20_02415	ENOG4105CHU	acetyl-coa acetyltransferase
C6I20_02420	ENOG4105D82	Glutamate dehydrogenase
C6I20_02425	ENOG4105E2A	Dehydrogenase
C6I20_02435	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
C6I20_02440	ENOG4108URH	decarboxylase
C6I20_02445	ENOG4105EEI	dihydropteroate synthase
C6I20_02450	ENOG4108R3E	Dna-3-methyladenine glycosylase i
C6I20_02460	ENOG4108UKI	Enoyl-CoA hydratase
C6I20_02475	ENOG4107ZBN	O-methyltransferase
C6I20_02495	ENOG410630M	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
C6I20_02505	ENOG4105C5H	ABC transporter
C6I20_02515	ENOG4105CJW	magnesium transporter
C6I20_02550	ENOG4105C1G	acyl-Coa dehydrogenase
C6I20_02560	ENOG4105DJG	MaoC domain protein dehydratase
C6I20_02600	ENOG4107QJE	Chromosome Partitioning Protein
C6I20_02610	ENOG4105C1J	atp-dependent rna helicase
C6I20_02650	ENOG4105C4R	Atp-dependent dna helicase
C6I20_02655	ENOG4105C4R	Atp-dependent dna helicase
C6I20_02705	ENOG41063PX	domain protein
C6I20_02715	ENOG4105DJZ	UPF0182 protein
C6I20_02730	ENOG4105E39	Enoyl-CoA hydratase
C6I20_02735	ENOG4105CSU	acyl-Coa dehydrogenase
C6I20_02760	ENOG41082SX	arsR family transcriptional regulator
C6I20_02860	ENOG4107RN6	Monooxygenase
C6I20_02875	ENOG4105C1G	acyl-Coa dehydrogenase
C6I20_02880	ENOG4105CHR	reductase
C6I20_02905	ENOG4105CSU	acyl-Coa dehydrogenase
C6I20_02940	ENOG4105EMU	Dehydrogenase
C6I20_02945	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
C6I20_02950	ENOG4105ETE	Transcriptional regulator (LacI family
C6I20_02965	ENOG4105ETE	Transcriptional regulator (LacI family
C6I20_02995	ENOG4105C2J	ABC transporter
C6I20_03000	ENOG4105CNN	ABC, transporter
C6I20_03005	ENOG4105CNN	ABC, transporter
C6I20_03015	ENOG4105DG4	malate L-lactate dehydrogenase
C6I20_03050	ENOG4105XDV	
C6I20_03080	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
C6I20_03090	ENOG4105WH1	Two component transcriptional regulator luxr family
C6I20_03095	ENOG4105BZU	Histidine kinase
C6I20_03145	ENOG4105CGD	Nad-dependent epimerase dehydratase
C6I20_03185	ENOG4108SGK	Tetr family transcriptional regulator
C6I20_03190	ENOG4105D2B	acyl-CoA dehydrogenase
C6I20_03210	ENOG4105X7H	acyl-CoA dehydrogenase
C6I20_03230	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
C6I20_03240	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
C6I20_03245	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
C6I20_03260	ENOG4108KC1	acyl-Coa dehydrogenase
C6I20_03265	ENOG41088PD	hydrolase
C6I20_03300	ENOG4105BZG	amino acid carrier protein
C6I20_03305	ENOG4105D2B	acyl-CoA dehydrogenase
C6I20_03310	ENOG4105D2B	acyl-CoA dehydrogenase
C6I20_03315	ENOG4105CC9	acyl-Coa dehydrogenase
C6I20_03320	ENOG4108IPT	Naphthoate synthase
C6I20_03325	ENOG4105CEY	Amp-dependent synthetase and ligase
C6I20_03330	ENOG4105CC9	acyl-Coa dehydrogenase
C6I20_03340	ENOG4108RZE	Tetr family transcriptional regulator
C6I20_03345	ENOG4105F2C	Acetyl-CoA acetyltransferase
C6I20_03355	ENOG4108QIU	Dehydrogenase
C6I20_03370	ENOG4105EA8	2-Nitropropane dioxygenase
C6I20_03385	ENOG41060WC	Enoyl-CoA hydratase
C6I20_03390	ENOG4105CHR	reductase
C6I20_03395	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
C6I20_03400	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
C6I20_03405	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
C6I20_03420	ENOG4105C26	Dehydrogenase
C6I20_03425	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
C6I20_03430	ENOG4105F2C	Acetyl-CoA acetyltransferase
C6I20_03435	ENOG4106A3M	Cytochrome p-450
C6I20_03460	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
C6I20_03465	ENOG4105CEY	Amp-dependent synthetase and ligase
C6I20_03485	ENOG4105J5T	Amp-dependent synthetase and ligase
C6I20_03490	ENOG4108KC2	acyl-Coa dehydrogenase
C6I20_03495	ENOG4105X7H	acyl-CoA dehydrogenase
C6I20_03510	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
C6I20_03515	ENOG4107EFR	Flavocytochrome c
C6I20_03575	ENOG4105CHR	reductase
C6I20_03625	ENOG4105E39	Enoyl-CoA hydratase
C6I20_03630	ENOG4105D74	hydrolase
C6I20_03640	ENOG4105CHR	reductase
C6I20_03645	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
C6I20_03650	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C6I20_03655	ENOG4105CHU	acetyl-coa acetyltransferase
C6I20_03660	ENOG4105CGU	Enoyl-CoA hydratase
C6I20_03665	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C6I20_03695	ENOG4105EG6	Saccharopine dehydrogenase
C6I20_03700	ENOG4105CEY	Amp-dependent synthetase and ligase
C6I20_03705	ENOG4105CHR	reductase
C6I20_03710	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
C6I20_03715	ENOG4105CEU	Arginine dihydrolase
C6I20_03720	ENOG4105DBV	ornithine carbamoyltransferase
C6I20_03725	ENOG4105C5B	carbamate kinase
C6I20_03740	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
C6I20_03765	ENOG4105EUB	pirin domain protein
C6I20_03770	ENOG4105GCF	PGAM
C6I20_03775	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
C6I20_03780	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
C6I20_03795	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
C6I20_03805	ENOG41083TI	Protein CrcB homolog
C6I20_03810	ENOG4107JBM	CrcB-like protein
C6I20_03840	ENOG4105DBE	peroxidase
C6I20_03875	ENOG4108YYC	ycei family
C6I20_03880	ENOG4105U5Y	Transcriptional regulator
C6I20_03885	ENOG4105C1G	acyl-Coa dehydrogenase
C6I20_03890	ENOG4105CHU	acetyl-coa acetyltransferase
C6I20_03895	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
C6I20_03905	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
C6I20_03910	ENOG4105IBS	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
C6I20_03930	ENOG4105D8K	carboxyl transferase
C6I20_03935	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
C6I20_03945	ENOG4108Z18	K06886 hemoglobin
C6I20_03950	ENOG4105D8X	mechanosensitive ion channel
C6I20_03970	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
C6I20_03975	ENOG4105MC2	DSBA oxidoreductase
C6I20_04025	ENOG4105E39	Enoyl-CoA hydratase
C6I20_04035	ENOG4105CEY	Amp-dependent synthetase and ligase
C6I20_04080	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
C6I20_04100	ENOG4105FDP	GntR family transcriptional regulator
C6I20_04105	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
C6I20_04110	ENOG4105D7K	pfkb domain protein
C6I20_04120	ENOG4105DH8	myo-inositol catabolism
C6I20_04125	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
C6I20_04130	ENOG4105C26	Dehydrogenase
C6I20_04135	ENOG4105D4B	ABC, transporter
C6I20_04140	ENOG4105CNN	ABC, transporter
C6I20_04145	ENOG4105C2J	ABC transporter
C6I20_04150	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
C6I20_04155	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
C6I20_04160	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
C6I20_04170	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C6I20_04175	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C6I20_04180	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
C6I20_04185	ENOG4105EG6	Saccharopine dehydrogenase
C6I20_04200	ENOG4106VEM	tagatose-6-phosphate kinase
C6I20_04205	ENOG4105E98	transcriptional regulator DeoR family
C6I20_04210	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
C6I20_04215	ENOG4105CPQ	Dehydrogenase
C6I20_04220	ENOG4105JF0	Phosphoenolpyruvate-dependent sugar phosphotransferase system, eiia 2
C6I20_04235	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
C6I20_04240	ENOG4105EYF	MMPL domain protein
C6I20_04245	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
C6I20_04255	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
C6I20_04270	ENOG4105DJ2	Major Facilitator Superfamily
C6I20_04280	ENOG4105C03	ribonuclease
C6I20_04285	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
C6I20_04290	ENOG4105K46	50S ribosomal protein l27
C6I20_04295	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C6I20_04300	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
C6I20_04305	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
C6I20_04310	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
C6I20_04320	ENOG4105CVJ	phosphoglycerate mutase
C6I20_04355	ENOG4105DXI	Major Facilitator superfamily
C6I20_04360	ENOG4105C9K	Endothelin-converting enzyme 1
C6I20_04390	ENOG4108MKI	Glycosyl transferase, family 2
C6I20_04435	ENOG4105CZN	Potassium uptake protein
C6I20_04440	ENOG4107ZYR	domain protein
C6I20_04445	ENOG4105C8T	Leucyl-tRNA synthetase
C6I20_04450	ENOG4105EPR	degv family
C6I20_04455	ENOG4105KQC	Competence protein
C6I20_04475	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
C6I20_04480	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
C6I20_04490	ENOG4108RPX	mosc domain containing protein
C6I20_04505	ENOG4108IQE	Amp-dependent synthetase and ligase
C6I20_04525	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
C6I20_04530	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
C6I20_04535	ENOG4107YU2	histidine triad (hIT) protein
C6I20_04545	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
C6I20_04560	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
C6I20_04570	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
C6I20_04580	ENOG4105DCG	PHP domain protein
C6I20_04595	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C6I20_04615	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
C6I20_04625	ENOG4105C26	Dehydrogenase
C6I20_04635	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
C6I20_04640	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
C6I20_04650	ENOG4105ERH	Fumarylacetoacetate hydrolase
C6I20_04655	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
C6I20_04710	ENOG41069M3	Transcriptional regulator
C6I20_04715	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C6I20_04720	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C6I20_04735	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
C6I20_04740	ENOG4105C28	cystathionine
C6I20_04745	ENOG4105CPF	Cell wall formation (By similarity)
C6I20_04770	ENOG4105DV0	amidase (EC 3.5.1.4
C6I20_04775	ENOG4105VB9	50S ribosomal protein l28
C6I20_04780	ENOG4105DP4	dak2 domain fusion protein ylov
C6I20_04790	ENOG4106H78	methyltransferase
C6I20_04795	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
C6I20_04800	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C6I20_04810	ENOG41084BZ	50S ribosomal protein L32
C6I20_04815	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
C6I20_04820	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
C6I20_04825	ENOG4105WQG	acetyltransferase
C6I20_04830	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
C6I20_04845	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C6I20_04860	ENOG4107W19	lmbE family
C6I20_04910	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
C6I20_04965	ENOG4105VPX	protein, conserved in bacteria
C6I20_04975	ENOG4107TPS	domain protein
C6I20_04985	ENOG4105EYF	MMPL domain protein
C6I20_04990	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C6I20_04995	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C6I20_05005	ENOG4105CEY	Amp-dependent synthetase and ligase
C6I20_05015	ENOG4105CVJ	phosphoglycerate mutase
C6I20_05020	ENOG4107XFJ	UPF0246 protein
C6I20_05065	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
C6I20_05080	ENOG4105C4K	Nad synthetase
C6I20_05090	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
C6I20_05095	ENOG4105KIU	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
C6I20_05100	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
C6I20_05130	ENOG4105EJ2	Transcriptional regulator
C6I20_05185	ENOG4105XTG	Pfam:DUF156
C6I20_05190	ENOG4105D82	Glutamate dehydrogenase
C6I20_05195	ENOG4108J2P	Alpha beta hydrolase fold
C6I20_05200	ENOG4105MC2	DSBA oxidoreductase
C6I20_05205	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
C6I20_05210	ENOG4105ETX	regulatoR
C6I20_05215	ENOG41062D9	Histidine kinase
C6I20_05230	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
C6I20_05235	ENOG4105CRK	lysyL-tRNA synthetase
C6I20_05270	ENOG4105D2B	acyl-CoA dehydrogenase
C6I20_05275	ENOG4105D2B	acyl-CoA dehydrogenase
C6I20_05280	ENOG4105CHR	reductase
C6I20_05315	ENOG4105CPQ	Dehydrogenase
C6I20_05330	ENOG4106E1W	protein with protein kinase and helix-hairpin-helix DNA-binding
C6I20_05350	ENOG4105C5F	glutamine synthetase
C6I20_05365	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
C6I20_05370	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
C6I20_05400	ENOG4105ED2	Beta-lactamase
C6I20_05405	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
C6I20_05410	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
C6I20_05430	ENOG4105D0M	Protease HtpX homolog
C6I20_05440	ENOG4105XT2	Transcriptional regulator
C6I20_05460	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
C6I20_05465	ENOG4105BZ9	Cytochrome C oxidase, subunit I
C6I20_05470	ENOG4105MCD	Part of cytochrome c oxidase, its function is
C6I20_05480	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
C6I20_05485	ENOG4107EUI	c reductase, iron-sulfur
C6I20_05490	ENOG4107UDY	cytochrome C
C6I20_05495	ENOG4105CCU	oxidase (Subunit III)
C6I20_05505	ENOG4107S1N	anthranilate phosphoribosyltransferase
C6I20_05535	ENOG4108IQE	Amp-dependent synthetase and ligase
C6I20_05550	ENOG4105DKQ	ROK family
C6I20_05555	ENOG4105DKQ	ROK family
C6I20_05575	ENOG4105CTQ	phosphohexokinase
C6I20_05585	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
C6I20_05630	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C6I20_05645	ENOG4108V6E	Cell division protein mraZ
C6I20_05650	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
C6I20_05660	ENOG4105CJN	penicillin-binding protein
C6I20_05665	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
C6I20_05675	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
C6I20_05680	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
C6I20_05690	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
C6I20_05695	ENOG4105DFU	Cell wall formation (By similarity)
C6I20_05700	ENOG4105ME9	cell division protein FtsQ
C6I20_05705	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
C6I20_05710	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
C6I20_05715	ENOG4105DFA	alanine racemase domain protein
C6I20_05720	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
C6I20_05735	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
C6I20_05775	ENOG4105C0B	DNA polymerase III (alpha subunit)
C6I20_05785	ENOG4108Z66	YbaK ebsC protein
C6I20_05790	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
C6I20_05795	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C6I20_05800	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
C6I20_05805	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
C6I20_05810	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
C6I20_05815	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
C6I20_05820	ENOG4105BZ1	(ABC) transporter
C6I20_05825	ENOG4105BZ1	(ABC) transporter
C6I20_05830	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
C6I20_05865	ENOG4105DK0	Indole-3-glycerol phosphate synthase
C6I20_05870	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
C6I20_05875	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
C6I20_05880	ENOG4107TBN	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
C6I20_05890	ENOG4105CBC	glutamate synthase
C6I20_05900	ENOG4105CA9	Pyruvate kinase
C6I20_05920	ENOG4108IV0	ABC, transporter
C6I20_05925	ENOG4105C0Z	ABC transporter
C6I20_05930	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
C6I20_05935	ENOG4105C32	Amino acid ABC transporter (Permease)
C6I20_05940	ENOG4108UQV	Membrane
C6I20_05965	ENOG4108RG3	short-chain dehydrogenase reductase
C6I20_05970	ENOG4105IQ5	FAD linked oxidase domain protein
C6I20_05975	ENOG4106YN8	Prenyltransferase
C6I20_05980	ENOG4108I69	Glycosyl transferases group 1
C6I20_05985	ENOG4108M6P	methyltransferase
C6I20_05990	ENOG41073B4	coagulation factor 5 8 type domain-containing protein
C6I20_06010	ENOG4105DFM	M18 family aminopeptidase
C6I20_06015	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
C6I20_06035	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
C6I20_06040	ENOG4105I8R	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C6I20_06050	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C6I20_06065	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C6I20_06090	ENOG4107UWP	Major facilitator superfamily MFS_1
C6I20_06100	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C6I20_06105	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
C6I20_06125	ENOG4107W53	thymidine kinase
C6I20_06135	ENOG4105EN6	Membrane
C6I20_06140	ENOG4105C26	Dehydrogenase
C6I20_06150	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
C6I20_06175	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
C6I20_06200	ENOG4107VEG	TrkA-N domain protein
C6I20_06205	ENOG4105C0X	amino acid
C6I20_06210	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C6I20_06225	ENOG4107QM5	aconitate hydratase
C6I20_06230	ENOG4105DFW	ABC transporter
C6I20_06235	ENOG4105C2J	ABC transporter
C6I20_06240	ENOG4108HWW	ABC transporter
C6I20_06245	ENOG4105E2R	ROK family
C6I20_06250	ENOG41066F8	ROK family
C6I20_06270	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
C6I20_06280	ENOG4105C29	acyl-CoA thioesterase
C6I20_06295	ENOG4105CHR	reductase
C6I20_06300	ENOG4105CHU	acetyl-coa acetyltransferase
C6I20_06320	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
C6I20_06335	ENOG4105CUB	amino acid
C6I20_06355	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
C6I20_06360	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
C6I20_06365	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
C6I20_06375	ENOG4105CIE	May be required for sporulation (By similarity)
C6I20_06380	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
C6I20_06385	ENOG4105BZA	Phosphoglycerate kinase
C6I20_06390	ENOG4105CP7	Triose-phosphate isomerase
C6I20_06420	ENOG4105C89	phosphohexose isomerase
C6I20_06425	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
C6I20_06435	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
C6I20_06460	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
C6I20_06485	ENOG4105DQE	DNA ligase
C6I20_06515	ENOG4105C3K	feS assembly ATPase SufC
C6I20_06520	ENOG4105C9B	Cysteine desulfurase
C6I20_06525	ENOG4108UNV	SUF system FeS assembly protein, NifU family
C6I20_06530	ENOG4105VG1	fes assembly suf system protein
C6I20_06535	ENOG4105C5H	ABC transporter
C6I20_06560	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C6I20_06575	ENOG4105WKW	Pfam:DUF1458
C6I20_06585	ENOG4105EAC	phosphoserine phosphatase
C6I20_06590	ENOG4105DKW	ABC transporter
C6I20_06610	ENOG4108V1U	phospholipid-binding protein
C6I20_06625	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
C6I20_06630	ENOG4105C1G	acyl-Coa dehydrogenase
C6I20_06635	ENOG4105C1G	acyl-Coa dehydrogenase
C6I20_06655	ENOG41081K0	peptidylprolyl cis-trans isomerase
C6I20_06660	ENOG4105CQ7	ATP-dependent helicase
C6I20_06670	ENOG4106BRA	Membrane
C6I20_06730	ENOG4105CHR	reductase
C6I20_06765	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C6I20_06785	ENOG4107SGM	protein serine threonine phosphatase
C6I20_06790	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
C6I20_06805	ENOG4105EA8	2-Nitropropane dioxygenase
C6I20_06820	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
C6I20_06830	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
C6I20_06840	ENOG4108FN7	Aldo keto reductase
C6I20_06845	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
C6I20_06850	ENOG4105D7N	magnesium and cobalt transport protein CorA
C6I20_06855	ENOG4105C8N	cysteinyl-tRNA synthetase
C6I20_06875	ENOG4105C3R	Methionine synthase
C6I20_06880	ENOG4107VXZ	Hydrolase
C6I20_06900	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
C6I20_06910	ENOG4105E5F	proteasome
C6I20_06920	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
C6I20_06925	ENOG4105F7N	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
C6I20_06930	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
C6I20_06935	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
C6I20_06955	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
C6I20_06960	ENOG4105CBD	Diacylglycerol kinase
C6I20_06970	ENOG4105HFS	5'-3' exonuclease
C6I20_06990	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
C6I20_06995	ENOG4105Q70	
C6I20_07000	ENOG4105CSH	Transporter
C6I20_07015	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
C6I20_07020	ENOG4105E8R	UPF0173 metal-dependent hydrolase
C6I20_07055	ENOG4108D32	Methyltransferase
C6I20_07085	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
C6I20_07090	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
C6I20_07105	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
C6I20_07135	ENOG4105K6V	RNA polymerase
C6I20_07140	ENOG4105RNG	membrane
C6I20_07150	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C6I20_07175	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
C6I20_07225	ENOG4105C8Y	Acetylornithine aminotransferase
C6I20_07240	ENOG410848D	S4 domain protein YaaA
C6I20_07255	ENOG4108URH	decarboxylase
C6I20_07285	ENOG4105CSV	Glutaminase
C6I20_07295	ENOG4105CHH	sulfate transporter
C6I20_07300	ENOG4107S91	Sodium hydrogen exchanger
C6I20_07310	ENOG4105CJ1	ABC, transporter
C6I20_07325	ENOG4105D64	Mechanosensitive ion channel
C6I20_07370	ENOG4105WH1	Two component transcriptional regulator luxr family
C6I20_07385	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C6I20_07390	ENOG4108KPJ	rna polymerase sigma factor
C6I20_07410	ENOG4105YIP	Tetr family transcriptional regulator
C6I20_07415	ENOG4105EYF	MMPL domain protein
C6I20_07420	ENOG4108VK3	Cupin 2 Conserved Barrel Domain Protein
C6I20_07445	ENOG4108IUE	nitrate reductase beta subunit
C6I20_07460	ENOG4105D3R	alkyl hydroperoxide reductase
C6I20_07465	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
C6I20_07470	ENOG4105FDP	GntR family transcriptional regulator
C6I20_07480	ENOG4108VCT	Sulfite exporter TauE/SafE
C6I20_07495	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C6I20_07500	ENOG4105EB3	Histidine kinase
C6I20_07505	ENOG4107R16	Multicopper oxidase
C6I20_07535	ENOG4105CEY	Amp-dependent synthetase and ligase
C6I20_07550	ENOG4105E2A	Dehydrogenase
C6I20_07555	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
C6I20_07560	ENOG4105D9P	serine threonine protein kinase
C6I20_07595	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
C6I20_07630	ENOG4107SID	ATP-dependent exodnase (exonuclease v)
C6I20_07655	ENOG4108EHY	type IV secretion system
C6I20_07695	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
C6I20_07700	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
C6I20_07730	ENOG4105E6M	Sulphatase-modifying factor protein
C6I20_07835	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)
C6I20_07870	ENOG4105WH1	Two component transcriptional regulator luxr family
C6I20_07880	ENOG4105CSU	acyl-Coa dehydrogenase
C6I20_07890	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
C6I20_07895	ENOG4105C7H	Helicase, RecD TraA family
C6I20_07900	ENOG4107QKA	exodeoxyribonuclease V beta
C6I20_07905	ENOG4105DSY	exodeoxyribonuclease V, gamma
C6I20_07935	ENOG4108IMY	Transcriptional regulator
C6I20_07960	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
C6I20_07965	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
C6I20_07970	ENOG4107RJX	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
C6I20_07975	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
C6I20_08025	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C6I20_08030	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
C6I20_08040	ENOG4108TAG	Histidine kinase
C6I20_08065	ENOG4105D9P	serine threonine protein kinase
C6I20_08080	ENOG4105RYD	Toxic component of a toxin-antitoxin (TA) module. A
C6I20_08100	ENOG4105EE1	crotonyl-CoA reductase
C6I20_08110	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
C6I20_08115	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C6I20_08120	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
C6I20_08130	ENOG4105Y3U	Transglycosylase-associated protein
C6I20_08135	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
C6I20_08145	ENOG4105CHP	RNA polymerase
C6I20_08165	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C6I20_08195	ENOG4107S2Z	UPF0761 membrane protein
C6I20_08205	ENOG4105CHR	reductase
C6I20_08210	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
C6I20_08225	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
C6I20_08230	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
C6I20_08235	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
C6I20_08260	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
C6I20_08300	ENOG4105CDA	abc transporter atp-binding protein
C6I20_08305	ENOG4107UBR	Extracellular solute-binding protein family 3
C6I20_08310	ENOG4108Q1T	ABC transporter
C6I20_08315	ENOG4105DRP	amino acid AbC transporter
C6I20_08340	ENOG4105KC9	Modulates RecA activity (By similarity)
C6I20_08345	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
C6I20_08355	ENOG4105WBV	Transcriptional regulator
C6I20_08360	ENOG4105CEV	competence damage-inducible protein
C6I20_08365	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
C6I20_08375	ENOG4107QZI	cell division protein FtsK
C6I20_08385	ENOG4105CN5	Metallo-Beta-Lactamase
C6I20_08390	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C6I20_08410	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
C6I20_08435	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
C6I20_08440	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
C6I20_08445	ENOG4107R72	Ceramidase
C6I20_08450	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
C6I20_08455	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
C6I20_08460	ENOG4108VQR	secreted hydrolase
C6I20_08470	ENOG4105DTN	riboflavin biosynthesis protein ribF
C6I20_08475	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
C6I20_08480	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
C6I20_08485	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
C6I20_08490	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
C6I20_08505	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
C6I20_08520	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
C6I20_08530	ENOG4108ZJ4	polysaccharide deacetylase
C6I20_08580	ENOG4105EUJ	GTP cyclohydrolase i
C6I20_08590	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
C6I20_08595	ENOG4105DZP	Membrane-associated zinc metalloprotease
C6I20_08610	ENOG4105CJ1	ABC, transporter
C6I20_08615	ENOG4105BZU	Histidine kinase
C6I20_08620	ENOG4105WH1	Two component transcriptional regulator luxr family
C6I20_08635	ENOG4105C26	Dehydrogenase
C6I20_08640	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
C6I20_08645	ENOG4105D38	putrescine abc transporter
C6I20_08650	ENOG4105F38	ABC transporter, permease
C6I20_08655	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C6I20_08685	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
C6I20_08695	ENOG4105CAT	Cytidine monophosphate kinase
C6I20_08710	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
C6I20_08715	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
C6I20_08740	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
C6I20_08750	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
C6I20_08755	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
C6I20_08770	ENOG4105DSU	hydrolase
C6I20_08800	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
C6I20_08805	ENOG4105SHT	UspA domain-containing protein
C6I20_08815	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
C6I20_08820	ENOG4108VX5	3-methyladenine DNA glycosylase
C6I20_08825	ENOG4105CH7	arginosuccinase
C6I20_08830	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
C6I20_08835	ENOG4105DBV	ornithine carbamoyltransferase
C6I20_08840	ENOG4105C8Y	Acetylornithine aminotransferase
C6I20_08845	ENOG4105CAS	nag kinase
C6I20_08850	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
C6I20_08855	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
C6I20_08870	ENOG4108V0P	LemA family
C6I20_08875	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
C6I20_08880	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
C6I20_08885	ENOG4105BZU	Histidine kinase
C6I20_08890	ENOG4108RWN	rrna methyltransferase
C6I20_08895	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
C6I20_08900	ENOG41084BS	50S ribosomal protein L35
C6I20_08905	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
C6I20_08925	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
C6I20_08930	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
C6I20_08935	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
C6I20_08940	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
C6I20_08955	ENOG4105DJV	ribulose-phosphate 3-epimerase
C6I20_08970	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
C6I20_08980	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
C6I20_08990	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
C6I20_08995	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
C6I20_09010	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
C6I20_09015	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
C6I20_09020	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
C6I20_09025	ENOG4105CD3	dihydroorotase
C6I20_09030	ENOG4105CXT	aspartate transcarbamylase
C6I20_09035	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
C6I20_09050	ENOG4108IJ8	ABC transporter
C6I20_09055	ENOG4105E90	ABC transporter
C6I20_09065	ENOG410803B	Involved in the transcription termination process (By similarity)
C6I20_09070	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
C6I20_09080	ENOG4105D49	3-dehydroquinate synthase
C6I20_09085	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
C6I20_09090	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
C6I20_09095	ENOG4105KPY	Small multidrug resistance protein
C6I20_09105	ENOG4105E2X	shikimate dehydrogenase
C6I20_09115	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
C6I20_09120	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
C6I20_09140	ENOG4105C9M	aspartyl-trna synthetase
C6I20_09145	ENOG4105CUT	histidyl-tRNA synthetase
C6I20_09155	ENOG4105C99	atpase involved in dna repair
C6I20_09165	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
C6I20_09170	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
C6I20_09180	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C6I20_09185	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C6I20_09195	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
C6I20_09200	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
C6I20_09205	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
C6I20_09210	ENOG4105CDY	transcriptional regulatory protein
C6I20_09215	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
C6I20_09250	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
C6I20_09260	ENOG4105URP	P-aminobenzoate N-oxygenase AurF
C6I20_09265	ENOG4108VTU	Cdp-alcohol phosphatidyltransferase
C6I20_09275	ENOG4105C22	threonyL-tRNA synthetase
C6I20_09280	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
C6I20_09295	ENOG4107RN6	Monooxygenase
C6I20_09365	ENOG4105CSU	acyl-Coa dehydrogenase
C6I20_09390	ENOG4105CSR	polyphosphate kinase 2
C6I20_09400	ENOG4105E0X	reductase
C6I20_09405	ENOG4107JTW	chlorite dismutase
C6I20_09410	ENOG4105C1Q	protoporphyrinogen oxidase
C6I20_09415	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
C6I20_09440	ENOG4107SET	aldo keto reductase
C6I20_09450	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C6I20_09495	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
C6I20_09505	ENOG4105WAP	TPR repeat-containing protein
C6I20_09515	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
C6I20_09525	ENOG4105P52	geranylgeranyl reductase
C6I20_09545	ENOG4105BZU	Histidine kinase
C6I20_09560	ENOG4107G87	m6 family metalloprotease domain protein
C6I20_09570	ENOG4105D8V	Glucose sorbosone dehydrogenase
C6I20_09575	ENOG4108DT4	serine threonine protein kinase
C6I20_09585	ENOG41080RH	Thioredoxin
C6I20_09600	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
C6I20_09615	ENOG4105C6Z	Gluconate
C6I20_09625	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
C6I20_09630	ENOG4105C0D	helicase
C6I20_09650	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
C6I20_09665	ENOG4105NPQ	Pfam:DUF403
C6I20_09675	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
C6I20_09680	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
C6I20_09685	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
C6I20_09690	ENOG4105CE9	30S ribosomal protein S2
C6I20_09695	ENOG4105E4C	Lytic transglycosylase catalytic
C6I20_09700	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C6I20_09705	ENOG4105C79	DNA protecting protein DprA
C6I20_09710	ENOG4105C0P	Mg chelatase subunit ChlI
C6I20_09715	ENOG41080R2	UPF0102 protein
C6I20_09725	ENOG4107VRI	Transcriptional regulator
C6I20_09735	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C6I20_09740	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
C6I20_09745	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
C6I20_09750	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
C6I20_09755	ENOG41082KU	UPF0109 protein
C6I20_09760	ENOG4105K5M	30s ribosomal protein S16
C6I20_09775	ENOG4106YT9	Enoyl-CoA hydratase
C6I20_09785	ENOG4105K89	arsenate reductase
C6I20_09800	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
C6I20_09810	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
C6I20_09855	ENOG4105C2W	permease
C6I20_09870	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
C6I20_09880	ENOG4105DIK	(ABC) transporter
C6I20_09905	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
C6I20_09915	ENOG4108IJ0	Aspartate ammonia-lyase
C6I20_09920	ENOG4105CM2	brancheD-chain amino acid aminotransferase
C6I20_09925	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
C6I20_09935	ENOG4105CUB	amino acid
C6I20_09940	ENOG4105BZU	Histidine kinase
C6I20_09955	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
C6I20_09960	ENOG4108ZP8	Acetolactate synthase small subunit
C6I20_09975	ENOG4105C01	Dihydroxy-acid dehydratase
C6I20_10010	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
C6I20_10020	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C6I20_10025	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C6I20_10030	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C6I20_10045	ENOG4108W1A	pseudouridine synthase
C6I20_10060	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
C6I20_10070	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
C6I20_10080	ENOG4108JPW	Aminotransferase
C6I20_10085	ENOG4107QI6	Cysteine desulfurase
C6I20_10090	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
C6I20_10095	ENOG4108IYU	L-aspartate oxidase
C6I20_10100	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
C6I20_10110	ENOG4105C0B	DNA polymerase III (alpha subunit)
C6I20_10130	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C6I20_10135	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C6I20_10145	ENOG4105C10	Electron transfer flavoprotein
C6I20_10150	ENOG4105BZJ	Electron transfer flavoprotein
C6I20_10170	ENOG4108M6P	methyltransferase
C6I20_10185	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
C6I20_10190	ENOG41070F3	Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity)
C6I20_10195	ENOG4105CG3	alpha amylase, catalytic region
C6I20_10200	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
C6I20_10220	ENOG4105CD3	dihydroorotase
C6I20_10230	ENOG4105CPC	Aldo Keto reductase
C6I20_10285	ENOG4105C0H	protease
C6I20_10295	ENOG4105VEQ	Cold shock protein
C6I20_10330	ENOG4105CHU	acetyl-coa acetyltransferase
C6I20_10365	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C6I20_10375	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
C6I20_10385	ENOG4107YEV	ferritin
C6I20_10395	ENOG4105RFZ	Methylmalonyl-coA mutase
C6I20_10415	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
C6I20_10420	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
C6I20_10425	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
C6I20_10430	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
C6I20_10435	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C6I20_10440	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
C6I20_10445	ENOG4106DE0	ATP synthase
C6I20_10450	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
C6I20_10460	ENOG4105ESV	Glycosyl transferase, family 4
C6I20_10475	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C6I20_10480	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
C6I20_10485	ENOG4105VFB	Binds the 23S rRNA (By similarity)
C6I20_10500	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
C6I20_10505	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
C6I20_10510	ENOG4105D6E	homoserine dehydrogenase
C6I20_10520	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
C6I20_10525	ENOG4105C75	arginyL-tRNA synthetase
C6I20_10530	ENOG4108UNF	response regulator
C6I20_10540	ENOG4108Z9K	Osmotically inducible protein
C6I20_10550	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
C6I20_10555	ENOG4105CB2	alcohol dehydrogenase
C6I20_10600	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C6I20_10625	ENOG4105EMN	RNA polymerase sigma factor
C6I20_10630	ENOG4108RAV	Conserved protein
C6I20_10650	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
C6I20_10660	ENOG4107TK4	histidinol-phosphate phosphatase
C6I20_10665	ENOG41080XQ	Signal transduction protein with cbs domains
C6I20_10675	ENOG4108638	50S ribosomal protein L36
C6I20_10700	ENOG4105C1G	acyl-Coa dehydrogenase
C6I20_10715	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C6I20_10755	ENOG4105CI0	Citrate lyase
C6I20_10810	ENOG4105DKK	Benzoate
C6I20_10815	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
C6I20_10825	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
C6I20_10830	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
C6I20_10835	ENOG4108RQ5	Beta-lactamase domain-containing protein
C6I20_10840	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
C6I20_10845	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
C6I20_10865	ENOG4108Q7D	Domain of unknown function (DUF2017)
C6I20_10870	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
C6I20_10880	ENOG4108RWI	nicotinamidase
C6I20_10900	ENOG4107U7N	hydantoinase B oxoprolinase
C6I20_10905	ENOG4107RID	5-oxoprolinase (ATP-hydrolyzing)
C6I20_10910	ENOG4105RQI	acetone carboxylase gamma subunit
C6I20_10915	ENOG4107SZ9	Hydantoinase oxoprolinase
C6I20_10920	ENOG4107W6X	Transcriptional regulator
C6I20_10930	ENOG4105D6N	CoA-transferase, subunit a
C6I20_10935	ENOG4107QNJ	CoA-transferase subunit B
C6I20_10940	ENOG4105DEN	Luciferase family
C6I20_10970	ENOG4108UJU	UPF0301 protein
C6I20_10985	ENOG4108Q5F	Tetr family transcriptional regulator
C6I20_10990	ENOG4108R5T	secreted protein
C6I20_10995	ENOG4107QRT	dEAD DEAH box helicase
C6I20_11015	ENOG4105KZX	Pterin carbinolamine dehydratase
C6I20_11020	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
C6I20_11040	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
C6I20_11055	ENOG4105CAK	Cell division ATP-binding protein ftsE
C6I20_11065	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
C6I20_11100	ENOG4105D9P	serine threonine protein kinase
C6I20_11105	ENOG4108V5V	Serine Threonine protein kinase
C6I20_11115	ENOG4107QPV	Serine Threonine protein kinase
C6I20_11210	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C6I20_11215	ENOG4105BZU	Histidine kinase
C6I20_11220	ENOG4105EDW	glycosyl transferase, family 39
C6I20_11280	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
C6I20_11285	ENOG4105T0Z	Conserved Protein
C6I20_11290	ENOG4105WH1	Two component transcriptional regulator luxr family
C6I20_11295	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
C6I20_11300	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
C6I20_11305	ENOG4108MKR	lipoprotein lpqb
C6I20_11310	ENOG4105BZU	Histidine kinase
C6I20_11315	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C6I20_11320	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
C6I20_11340	ENOG4105W49	UPF0434 protein
C6I20_11365	ENOG4107RGC	Glycosyl transferase, family 2
C6I20_11370	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
C6I20_11390	ENOG4105EY8	ABC transporter
C6I20_11395	ENOG4108KGH	TRANSCRIPTIONal
C6I20_11405	ENOG4108KGH	TRANSCRIPTIONal
C6I20_11410	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
C6I20_11425	ENOG4108Z4U	Ferredoxin
C6I20_11450	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
C6I20_11465	ENOG4105QE3	oxidoreductase
C6I20_11500	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
C6I20_11515	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
C6I20_11545	ENOG4105E3J	oxidoreductase
C6I20_11595	ENOG4105BZU	Histidine kinase
C6I20_11600	ENOG4105WH1	Two component transcriptional regulator luxr family
C6I20_11605	ENOG4105C3G	gtp-binding protein
C6I20_11635	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
C6I20_11640	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C6I20_11645	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C6I20_11685	ENOG4105C9Q	fumarate hydratase class II
C6I20_11715	ENOG4108IAB	Phoh family
C6I20_11740	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
C6I20_11745	ENOG4108UT2	hemolysin iii
C6I20_11750	ENOG4105C7Z	Conserved Protein
C6I20_11755	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
C6I20_11770	ENOG4105T1M	mycothiol conjugate amidase mca
C6I20_11775	ENOG4105EMU	Dehydrogenase
C6I20_11785	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
C6I20_11790	ENOG4105C7B	Threonine dehydratase
C6I20_11805	ENOG4105MSB	protein, conserved in bacteria
C6I20_11815	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
C6I20_11820	ENOG4108VCA	G U mismatch-specific DNA glycosylase
C6I20_11825	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
C6I20_11830	ENOG4108R86	Transcriptional regulator
C6I20_11840	ENOG4105BZ1	(ABC) transporter
C6I20_11845	ENOG4105EUB	pirin domain protein
C6I20_11865	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
C6I20_11875	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
C6I20_11885	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
C6I20_11910	ENOG4105E39	Enoyl-CoA hydratase
C6I20_11920	ENOG4105CPC	Aldo Keto reductase
C6I20_11935	ENOG4105F9U	Dehydrogenase
C6I20_11955	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
C6I20_12005	ENOG4108KGH	TRANSCRIPTIONal
C6I20_12010	ENOG4105J5G	Transferase hexapeptide repeat containing protein
C6I20_12025	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
C6I20_12030	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
C6I20_12035	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
C6I20_12040	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
C6I20_12050	ENOG4107EF8	Glycosyl transferase (Group 1
C6I20_12125	ENOG4105D3Q	Sugar transferase
C6I20_12130	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
C6I20_12135	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
C6I20_12150	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
C6I20_12165	ENOG41062A4	Transcriptional regulator
C6I20_12170	ENOG4105C5H	ABC transporter
C6I20_12175	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
C6I20_12180	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
C6I20_12185	ENOG4106839	domain protein
C6I20_12190	ENOG4105F8V	Hydrolase, tatD family
C6I20_12195	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
C6I20_12225	ENOG4105VCQ	rubredoxin
C6I20_12230	ENOG41084UD	rubredoxin
C6I20_12235	ENOG4105EEF	Alkane 1-monooxygenase
C6I20_12260	ENOG4107QMS	site-determining protein
C6I20_12315	ENOG4105CJP	fad dependent oxidoreductase
C6I20_12320	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
C6I20_12330	ENOG4105DEN	Luciferase family
C6I20_12345	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C6I20_12350	ENOG4105BZU	Histidine kinase
C6I20_12360	ENOG410841Q	phosphoesterase PA-phosphatase related protein
C6I20_12375	ENOG4105DQR	SNARE associated Golgi
C6I20_12390	ENOG4105EXU	Membrane
C6I20_12405	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C6I20_12410	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C6I20_12425	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
C6I20_12435	ENOG4105CUJ	penicillin amidase
C6I20_12460	ENOG41080FJ	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
C6I20_12485	ENOG4107QN2	dihydrolipoyl dehydrogenase
C6I20_12505	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
C6I20_12520	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
C6I20_12550	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
C6I20_12560	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
C6I20_12605	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
C6I20_12610	ENOG4108Z0R	Transferase
C6I20_12615	ENOG4105C7N	Xanthine uracil vitamin C permease
C6I20_12630	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C6I20_12640	ENOG4108N0W	Major Facilitator superfamily
C6I20_12645	ENOG4105VEQ	Cold shock protein
C6I20_12650	ENOG4107H3J	ribonuclease
C6I20_12655	ENOG4105CEY	Amp-dependent synthetase and ligase
C6I20_12660	ENOG4105D3Q	Sugar transferase
C6I20_12710	ENOG4105C26	Dehydrogenase
C6I20_12715	ENOG4107RR1	TRANSCRIPTIONal
C6I20_12735	ENOG4105CJ1	ABC, transporter
C6I20_12740	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
C6I20_12755	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
C6I20_12780	ENOG4105VEQ	Cold shock protein
C6I20_12820	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
C6I20_12830	ENOG4105CVK	Glutamate decarboxylase
C6I20_12850	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
C6I20_12860	ENOG4105DCF	alanine dehydrogenase
C6I20_12880	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
C6I20_12895	ENOG4105ERH	Fumarylacetoacetate hydrolase
C6I20_12910	ENOG4105C1G	acyl-Coa dehydrogenase
C6I20_12915	ENOG4105M4P	Tetr family transcriptional regulator
C6I20_12920	ENOG4108ZJI	phenylacetic acid degradation protein
C6I20_12925	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
C6I20_12930	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
C6I20_12935	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
C6I20_12940	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
C6I20_12945	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
C6I20_12950	ENOG4105DXM	phenylacetic acid degradation protein
C6I20_12965	ENOG4107QSN	dihydrolipoamide acetyltransferase
C6I20_13000	ENOG4105C09	Bile acid
C6I20_13050	ENOG4105BZU	Histidine kinase
C6I20_13055	ENOG4105WH1	Two component transcriptional regulator luxr family
C6I20_13125	ENOG4105C8N	cysteinyl-tRNA synthetase
C6I20_13140	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
C6I20_13145	ENOG4108VJ1	Transcriptional regulator (CarD family
C6I20_13170	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
C6I20_13180	ENOG4107ZR7	Membrane
C6I20_13195	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
C6I20_13210	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C6I20_13215	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
C6I20_13220	ENOG4105CI3	gtp-binding protein typa
C6I20_13235	ENOG4105DIM	ABC transporter
C6I20_13240	ENOG4105CIG	ABC transporter
C6I20_13270	ENOG4105EIP	mannose-6-phosphate isomerase
C6I20_13280	ENOG4105D3Q	Sugar transferase
C6I20_13290	ENOG4107YJ4	chain length determinant protein
C6I20_13295	ENOG4107WAU	Protein tyrosine phosphatase
C6I20_13300	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
C6I20_13305	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
C6I20_13310	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
C6I20_13330	ENOG4105PKJ	carbohydrate binding
C6I20_13335	ENOG4105KHC	sulfurtransferase
C6I20_13360	ENOG4107NHD	transcriptional regulator
C6I20_13370	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
C6I20_13380	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
C6I20_13395	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
C6I20_13410	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
C6I20_13415	ENOG4105CJ3	phosphate transporter
C6I20_13465	ENOG4105D74	hydrolase
C6I20_13500	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
C6I20_13505	ENOG4107QQG	Dehydrogenase
C6I20_13510	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
C6I20_13520	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
C6I20_13555	ENOG4105KD7	acetyltransferase
C6I20_13560	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
C6I20_13575	ENOG4107R13	MMPL domain protein
C6I20_13590	ENOG4105E90	ABC transporter
C6I20_13645	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
C6I20_13650	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
C6I20_13680	ENOG4105CHR	reductase
C6I20_13690	ENOG4105CNN	ABC, transporter
C6I20_13695	ENOG4105C2J	ABC transporter
C6I20_13710	ENOG4105DTD	Dehydrogenase
C6I20_13715	ENOG4105CEY	Amp-dependent synthetase and ligase
C6I20_13730	ENOG4105D2B	acyl-CoA dehydrogenase
C6I20_13745	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
C6I20_13760	ENOG4105CEY	Amp-dependent synthetase and ligase
C6I20_13775	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
C6I20_13780	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C6I20_13810	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
C6I20_13850	ENOG4105C1J	atp-dependent rna helicase
C6I20_13865	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
C6I20_13870	ENOG410839H	phosphoribosylformylglycinamidine synthase
C6I20_13875	ENOG4105CEY	Amp-dependent synthetase and ligase
C6I20_13895	ENOG4105C8V	SAICAR synthetase
C6I20_13905	ENOG4105C83	adenylosuccinate lyase
C6I20_13910	ENOG4105C12	Phosphoribosylglycinamide synthetase
C6I20_13915	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
C6I20_13960	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
C6I20_13965	ENOG4108U4N	(sortase) family
C6I20_13985	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
C6I20_13995	ENOG4105J0Q	Transcriptional regulator
C6I20_14015	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
C6I20_14030	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
C6I20_14045	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
C6I20_14055	ENOG4108Z7F	N-acetyltransferase
C6I20_14070	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C6I20_14075	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
C6I20_14080	ENOG4105WN5	stage II sporulation protein
C6I20_14085	ENOG4108I5C	dEAD DEAH box helicase
C6I20_14145	ENOG4105EQK	-acetyltransferase
C6I20_14155	ENOG4105DHI	Methyltransferase
C6I20_14175	ENOG4107YJ4	chain length determinant protein
C6I20_14180	ENOG4108IAJ	Nad-dependent epimerase dehydratase
C6I20_14190	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
C6I20_14195	ENOG4108VQR	secreted hydrolase
C6I20_14215	ENOG4105CHR	reductase
C6I20_14250	ENOG4107ZYJ	bioY protein
C6I20_14255	ENOG4108JJB	ABC transporter
C6I20_14265	ENOG4108HRK	Histidine kinase
C6I20_14270	ENOG4108NEV	two component transcriptional regulator, LytTR family
C6I20_14290	ENOG4107QN1	sodium solute
C6I20_14295	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C6I20_14315	ENOG4105C0H	protease
C6I20_14320	ENOG4105P8F	nudix hydrolase
C6I20_14325	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C6I20_14340	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
C6I20_14370	ENOG4105N0U	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
C6I20_14375	ENOG4105BZ4	penicillin-binding protein
C6I20_14385	ENOG4105DIN	metallophosphoesterase
C6I20_14420	ENOG4105CVR	type I restriction-modification system
C6I20_14465	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C6I20_14475	ENOG4105CFH	Aspartokinase
C6I20_14485	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
C6I20_14500	ENOG4105CRQ	synthase (Component I)
C6I20_14520	ENOG4105X7H	acyl-CoA dehydrogenase
C6I20_14525	ENOG4105C1G	acyl-Coa dehydrogenase
C6I20_14550	ENOG4105ETE	Transcriptional regulator (LacI family
C6I20_14560	ENOG4105S9S	Binding-protein-dependent transport systems, inner membrane component
C6I20_14565	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
C6I20_14575	ENOG4108IJ9	(ABC) transporter
C6I20_14585	ENOG4108J2P	Alpha beta hydrolase fold
C6I20_14590	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
C6I20_14595	ENOG4105VNH	ABC transporter solute-binding protein
C6I20_14610	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C6I20_14640	ENOG4108N5B	2-phosphosulfolactate phosphatase
C6I20_14650	ENOG4105D7A	ATP-binding protein
C6I20_14665	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
C6I20_14680	ENOG4105CEY	Amp-dependent synthetase and ligase
C6I20_14695	ENOG4105C87	Aminotransferase class I and II
C6I20_14735	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
C6I20_14740	ENOG4105CHH	sulfate transporter
C6I20_14745	ENOG4107SWG	transcriptional regulator MERR family
C6I20_14780	ENOG4105CS9	pantothenic acid kinase
C6I20_14785	ENOG4108UZX	fmn reductase
C6I20_14790	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
C6I20_14800	ENOG4108Z6B	deaminase
C6I20_14805	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
C6I20_14810	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
C6I20_14815	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
C6I20_14820	ENOG4107SIQ	Naphthoate synthase
C6I20_14825	ENOG4105CHR	reductase
C6I20_14840	ENOG4105DUM	transcriptional regulator, lysR family
C6I20_14855	ENOG4105C26	Dehydrogenase
C6I20_14860	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
C6I20_14865	ENOG4105D81	ABC transporter, permease
C6I20_14870	ENOG4107TYH	extracellular solute-binding protein family 1
C6I20_14875	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C6I20_14900	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C6I20_14905	ENOG4105FDF	Could be involved in DNA repair (By similarity)
C6I20_14955	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
C6I20_14960	ENOG4106UW1	Major Facilitator superfamily
C6I20_14965	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
C6I20_14975	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
C6I20_14980	ENOG4105DRR	Transcriptional regulator, GntR family
C6I20_14985	ENOG4105CQB	FAD linked oxidase domain protein
C6I20_15015	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
C6I20_15020	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
C6I20_15075	ENOG4107QPI	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
C6I20_15090	ENOG4105CIS	alcohol dehydrogenase
C6I20_15105	ENOG410667J	hydrolase
C6I20_15110	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
C6I20_15120	ENOG4105CPT	Alpha beta hydrolase
C6I20_15125	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
C6I20_15150	ENOG4105CEU	Arginine dihydrolase
C6I20_15175	ENOG4108426	dNA-binding protein
C6I20_15180	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
C6I20_15195	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
C6I20_15205	ENOG4107QX3	carboxylase
C6I20_15210	ENOG4108RZE	Tetr family transcriptional regulator
C6I20_15215	ENOG4108594	Permease of the drug metabolite transporter
C6I20_15220	ENOG4107V2S	Transcriptional regulator
C6I20_15225	ENOG4105C57	major facilitator superfamily
C6I20_15270	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
C6I20_15290	ENOG4105TV9	FHA Domain-Containing protein
C6I20_15295	ENOG4105HZM	Fha domain containing protein
C6I20_15310	ENOG4105CJN	penicillin-binding protein
C6I20_15350	ENOG4105E39	Enoyl-CoA hydratase
C6I20_15365	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
C6I20_15370	ENOG4108J59	Extracellular solute-binding protein, family 5
C6I20_15375	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C6I20_15385	ENOG4108TCJ	secreted hydrolase
C6I20_15420	ENOG4105C5X	domain protein
C6I20_15445	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C6I20_15450	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C6I20_15460	ENOG4105K7N	UPF0232 protein
C6I20_15465	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
C6I20_15470	ENOG4108J5G	6-phosphogluconate dehydrogenase
C6I20_15475	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
C6I20_15480	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
C6I20_15495	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
C6I20_15500	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
C6I20_15510	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
C6I20_15515	ENOG4107QJE	Chromosome Partitioning Protein
C6I20_15525	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
C6I20_15530	ENOG4105C2J	ABC transporter
C6I20_15535	ENOG4105CNN	ABC, transporter
C6I20_15540	ENOG4105CNN	ABC, transporter
C6I20_15550	ENOG4105CEY	Amp-dependent synthetase and ligase
C6I20_15555	ENOG4105K63	Thioredoxin
C6I20_15560	ENOG4105C3M	thioredoxin reductase
C6I20_15565	ENOG4108DT4	serine threonine protein kinase
C6I20_15580	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
C6I20_15590	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
C6I20_15595	ENOG4105C32	Amino acid ABC transporter (Permease)
C6I20_15600	ENOG4108IQE	Amp-dependent synthetase and ligase
C6I20_15605	ENOG4105C0Z	ABC transporter
C6I20_15610	ENOG4108IV0	ABC, transporter
C6I20_15630	ENOG4105BZ4	penicillin-binding protein
C6I20_15640	ENOG4108TV1	Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor (By similarity)
C6I20_15670	ENOG4105CPC	Aldo Keto reductase
C6I20_15680	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C6I20_15685	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C6I20_15690	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
C6I20_15695	ENOG4107YH6	single-stranded DNA-binding protein
C6I20_15700	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
C6I20_15705	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
C6I20_15725	ENOG4105CDU	Replicative dna helicase
C6I20_15735	ENOG4107T5V	SNARE associated Golgi
C6I20_15750	ENOG4105BZ1	(ABC) transporter
C6I20_15755	ENOG4108MNP	Glycoprotein polysaccharide metabolism
C6I20_15765	ENOG4105VPX	protein, conserved in bacteria
C6I20_15795	ENOG4108JQ1	Dehydrogenase
C6I20_15815	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C6I20_15850	ENOG41085FC	arsR family transcriptional regulator
C6I20_15870	ENOG4105WH1	Two component transcriptional regulator luxr family
C6I20_15890	ENOG4107Z7P	Ferredoxin
C6I20_15950	ENOG4105DKW	ABC transporter
C6I20_15960	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
C6I20_15965	ENOG410846T	CoA-transferase family III
C6I20_15975	ENOG4105E2Y	ABC, transporter
C6I20_15990	ENOG4105CHU	acetyl-coa acetyltransferase
C6I20_15995	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C6I20_16030	ENOG4108TM9	integral membrane protein
C6I20_16035	ENOG4105CGD	Nad-dependent epimerase dehydratase
C6I20_16055	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
C6I20_16075	ENOG4105CGU	Enoyl-CoA hydratase
C6I20_16135	ENOG4107RR1	TRANSCRIPTIONal
C6I20_16140	ENOG4105F95	Monooxygenase
C6I20_16145	ENOG4105W0E	50S ribosomal protein L33
C6I20_16150	ENOG4105DWV	Homoserine O-trans-acetylase
C6I20_16165	ENOG4105F95	Monooxygenase
C6I20_16170	ENOG4105CJ1	ABC, transporter
C6I20_16185	ENOG4105BZU	Histidine kinase
C6I20_16190	ENOG4105WH1	Two component transcriptional regulator luxr family
C6I20_16210	ENOG4108RF4	Tetr family transcriptional regulator
C6I20_16225	ENOG4105C1G	acyl-Coa dehydrogenase
C6I20_16230	ENOG4107QX3	carboxylase
C6I20_16250	ENOG4105DRP	amino acid AbC transporter
C6I20_16255	ENOG4105CDA	abc transporter atp-binding protein
C6I20_16315	ENOG4107Y9U	Membrane
C6I20_16320	ENOG4105C0H	protease
C6I20_16325	ENOG41062D9	Histidine kinase
C6I20_16345	ENOG41082T9	Membrane
C6I20_16350	ENOG4108UZ3	Transporter
C6I20_16355	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C6I20_16365	ENOG4105CPP	Dehydrogenase, E1 component
C6I20_16370	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
C6I20_16405	ENOG4107QRI	Phosphoketolase
C6I20_16410	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
C6I20_16440	ENOG4108JJ8	(ABC) transporter
C6I20_16445	ENOG4108JJ9	ABC, transporter
C6I20_16450	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
C6I20_16455	ENOG4105C4M	(Ubiquinol oxidase) subunit I
C6I20_16470	ENOG4105K56	Transcriptional regulator
C6I20_16475	ENOG4105CSU	acyl-Coa dehydrogenase
C6I20_16485	ENOG4105JQN	Transcriptional regulator
C6I20_16495	ENOG4107USC	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
C6I20_16500	ENOG4105CMR	udp-glucose 4-epimerase
C6I20_16505	ENOG4105BZU	Histidine kinase
C6I20_16510	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C6I20_16555	ENOG4105CPQ	Dehydrogenase
C6I20_16560	ENOG4105D5U	fad dependent oxidoreductase
C6I20_16570	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C6I20_16575	ENOG4105DHP	deoxycytidine triphosphate deaminase
C6I20_16580	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
C6I20_16585	ENOG4108KPW	sugar kinase
C6I20_16590	ENOG4108KPW	sugar kinase
C6I20_16595	ENOG4107QKS	N-acylglucosamine 2-epimerase
C6I20_16620	ENOG4105C84	Histidine ammonia-lyase
C6I20_16625	ENOG4105CGP	Urocanate hydratase
C6I20_16640	ENOG4105CI2	imidazolone-5-propionate hydrolase
C6I20_16645	ENOG4105K5B	UPF0225 protein
C6I20_16650	ENOG4105DF6	Fe-S oxidoreductase
C6I20_16655	ENOG4105E5T	Major Facilitator Superfamily
C6I20_16670	ENOG4105CJP	fad dependent oxidoreductase
C6I20_16675	ENOG4105JXB	ankyrin repeat-containing protein
C6I20_16705	ENOG4108JJB	ABC transporter
C6I20_16730	ENOG4105CHR	reductase
C6I20_16755	ENOG4105C72	UPF0176 protein
C6I20_16760	ENOG4108RZE	Tetr family transcriptional regulator
C6I20_16770	ENOG4105D2S	major facilitator superfamily
C6I20_16780	ENOG4105EYF	MMPL domain protein
C6I20_16795	ENOG4105CFG	Acts as a chaperone (By similarity)
C6I20_16800	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C6I20_16805	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
C6I20_16810	ENOG4105KNI	merR family transcriptional Regulator
C6I20_16830	ENOG41076QQ	Glycosyl transferase, family 2
C6I20_16840	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
C6I20_16855	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C6I20_16880	ENOG4105CEY	Amp-dependent synthetase and ligase