locus-tag	class	description
GWG05_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GWG05_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GWG05_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GWG05_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GWG05_00025	ENOG4108R6W	Transcriptional regulator, ARAC family
GWG05_00030	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
GWG05_00035	ENOG4108ZNX	Heat shock protein
GWG05_00040	ENOG4108ZNX	Heat shock protein
GWG05_00045	ENOG4105JKW	Valine--pyruvate aminotransferase
GWG05_00065	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
GWG05_00070	ENOG4105C08	Histidine kinase
GWG05_00075	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
GWG05_00080	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
GWG05_00085	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
GWG05_00095	ENOG4105DC8	reductase
GWG05_00100	ENOG4105BZU	Histidine kinase
GWG05_00105	ENOG4105BZS	acriflavin resistance protein
GWG05_00110	ENOG410624X	efflux transporter, rnd family, mfp subunit
GWG05_00115	ENOG4105Y7M	Transcriptional regulator, TetR family
GWG05_00145	ENOG4105DQF	Hydrolase
GWG05_00150	ENOG4108EUD	Lysophospholipase
GWG05_00155	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
GWG05_00160	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GWG05_00165	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
GWG05_00175	ENOG4105DKP	glycosyl transferase, family 9
GWG05_00180	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
GWG05_00190	ENOG4105EMK	carboxylate amino acid amine transporter
GWG05_00220	ENOG4108M6U	Universal stress protein A
GWG05_00225	ENOG4105RKW	reductase (By
GWG05_00230	ENOG4105BZU	Histidine kinase
GWG05_00235	ENOG41090A1	ferritin
GWG05_00240	ENOG4105CBX	hi0933 family
GWG05_00245	ENOG4105EU0	Major facilitator Superfamily
GWG05_00265	ENOG4108N3D	putative enzyme
GWG05_00270	ENOG4108NN8	Fimbrial protein
GWG05_00275	ENOG4108GWT	fimbrillin MatB
GWG05_00280	ENOG4107ZHV	Transcriptional regulator
GWG05_00290	ENOG410600T	transposase
GWG05_00305	ENOG4108HRK	Histidine kinase
GWG05_00310	ENOG4105DY9	regulatoR
GWG05_00315	ENOG4105FCD	Major Facilitator
GWG05_00320	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
GWG05_00325	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
GWG05_00330	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GWG05_00335	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
GWG05_00375	ENOG4105CUZ	uba thif-type nad fad binding protein
GWG05_00380	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
GWG05_00385	ENOG4105C9B	Cysteine desulfurase
GWG05_00390	ENOG4105C4R	Atp-dependent dna helicase
GWG05_00395	ENOG4105BZU	Histidine kinase
GWG05_00400	ENOG4105MPD	Cytochrome
GWG05_00405	ENOG4105CPQ	Dehydrogenase
GWG05_00410	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GWG05_00415	ENOG41062JF	Transcriptional regulator
GWG05_00420	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
GWG05_00465	ENOG4105DIQ	Transcriptional regulator
GWG05_00485	ENOG4105X6C	Flagellar basal body-associated protein FliL
GWG05_00490	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
GWG05_00495	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
GWG05_00500	ENOG4105E55	glycerol-3-phosphate acyltransferase
GWG05_00505	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
GWG05_00525	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
GWG05_00530	ENOG4105E0F	Histidine kinase
GWG05_00535	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GWG05_00540	ENOG41076HS	cation diffusion facilitator family transporter
GWG05_00545	ENOG4105D7W	serine acetyltransferase
GWG05_00555	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
GWG05_00560	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
GWG05_00565	ENOG4105C2M	dna polymerase I
GWG05_00570	ENOG4108Z0R	Transferase
GWG05_00605	ENOG4105CQ4	Transcriptional regulator
GWG05_00610	ENOG4105CNT	hydrolase family 2
GWG05_00615	ENOG4105FK9	beta-D-galactosidase beta subunit
GWG05_00620	ENOG4105E5D	amino acid
GWG05_00625	ENOG4108Y51	tRNA-binding protein
GWG05_00630	ENOG4105E5D	amino acid
GWG05_00635	ENOG4105DHU	Bile acid
GWG05_00665	ENOG4105CC0	LysR family Transcriptional regulator
GWG05_00675	ENOG4105UIB	(ABC) transporter
GWG05_00680	ENOG4108JQ9	ABC transporter
GWG05_00685	ENOG4105DIH	basic membrane
GWG05_00700	ENOG4105C4R	Atp-dependent dna helicase
GWG05_00715	ENOG4108UK5	Transposase
GWG05_00720	ENOG4105HEI	LysR family (Transcriptional regulator
GWG05_00735	ENOG41061EV	selenium-binding protein YdfZ
GWG05_00755	ENOG4108YH8	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
GWG05_00760	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
GWG05_00765	ENOG4105ECQ	AraC Family Transcriptional Regulator
GWG05_00770	ENOG4105FR1	rard protein
GWG05_00775	ENOG4105C26	Dehydrogenase
GWG05_00780	ENOG4108JCI	Transcriptional regulator
GWG05_00790	ENOG4105C26	Dehydrogenase
GWG05_00795	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GWG05_00800	ENOG4107R11	Transcriptional regulator
GWG05_00805	ENOG4108MGF	sugar kinase
GWG05_00825	ENOG4105CGY	Dna recombination protein
GWG05_00830	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GWG05_00835	ENOG4105C1A	potassium transporter peripheral membrane
GWG05_00840	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GWG05_00845	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GWG05_00850	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GWG05_00860	ENOG4105C79	DNA protecting protein DprA
GWG05_00865	ENOG4108RPN	Protein smg homolog
GWG05_00870	ENOG4108WI1	Dna topoisomerase
GWG05_00875	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GWG05_00880	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
GWG05_00885	ENOG4105E2X	shikimate dehydrogenase
GWG05_00890	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
GWG05_00895	ENOG4106RE7	Cytochrome
GWG05_00900	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
GWG05_00905	ENOG4105XCT	Protein of unknown function (DUF2489)
GWG05_00910	ENOG4105D4P	Coproporphyrinogen iii oxidase
GWG05_00915	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
GWG05_00920	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GWG05_00925	ENOG4105CUX	Signal transduction histidine kinase
GWG05_00935	ENOG4105C5F	glutamine synthetase
GWG05_00940	ENOG4105CI3	gtp-binding protein typa
GWG05_00945	ENOG4107S2Z	UPF0761 membrane protein
GWG05_00950	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
GWG05_00960	ENOG4105SUU	thioesterase domain
GWG05_00970	ENOG4105CB5	ATP-dependent DNA helicase recG
GWG05_00975	ENOG4105JIM	Phosphatidylserine synthase
GWG05_00980	ENOG4105C6Z	Gluconate
GWG05_00985	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
GWG05_00990	ENOG4105C01	Dihydroxy-acid dehydratase
GWG05_00995	ENOG4108UHU	Aldolase
GWG05_01010	ENOG4105DIQ	Transcriptional regulator
GWG05_01020	ENOG41063SB	peptidase
GWG05_01025	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GWG05_01030	ENOG4107YZP	Rhodanese domain protein
GWG05_01035	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
GWG05_01040	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
GWG05_01045	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
GWG05_01050	ENOG4105MJ2	Competence protein
GWG05_01055	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GWG05_01070	ENOG4105BZM	domain protein
GWG05_01075	ENOG4108RRZ	Transcription elongation factor GreB
GWG05_01085	ENOG4105E0F	Histidine kinase
GWG05_01095	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
GWG05_01100	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GWG05_01105	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GWG05_01110	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GWG05_01115	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GWG05_01120	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GWG05_01125	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
GWG05_01130	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GWG05_01135	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GWG05_01140	ENOG41083MP	50s ribosomal protein l29
GWG05_01145	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GWG05_01150	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GWG05_01155	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GWG05_01160	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GWG05_01165	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GWG05_01170	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GWG05_01175	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GWG05_01180	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
GWG05_01185	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GWG05_01190	ENOG4105VPB	50S ribosomal protein L30
GWG05_01195	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GWG05_01200	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GWG05_01205	ENOG41067V7	50S ribosomal protein L36
GWG05_01210	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GWG05_01215	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GWG05_01220	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GWG05_01225	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GWG05_01230	ENOG4108ZT0	50S ribosomal protein l17
GWG05_01285	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
GWG05_01290	ENOG4106NZI	LysR family Transcriptional regulator
GWG05_01295	ENOG4105EMU	Dehydrogenase
GWG05_01310	ENOG4105CUG	Oligopeptidase b
GWG05_01315	ENOG4105H1G	trap transporter solute receptor taxi family
GWG05_01330	ENOG4107FS9	Membrane
GWG05_01345	ENOG4105CR8	Transcriptional regulator
GWG05_01360	ENOG4105VVZ	metal-binding protein
GWG05_01365	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
GWG05_01375	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
GWG05_01385	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
GWG05_01395	ENOG4107RZC	phospholipase d
GWG05_01405	ENOG4105EJ2	Transcriptional regulator
GWG05_01410	ENOG4108Y73	Membrane
GWG05_01420	ENOG4106H78	methyltransferase
GWG05_01425	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GWG05_01430	ENOG4105CAK	Cell division ATP-binding protein ftsE
GWG05_01435	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
GWG05_01440	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GWG05_01445	ENOG41077A9	carbonic anhydrase
GWG05_01450	ENOG4105CZE	histidine utilization repressor
GWG05_01455	ENOG4105CI2	imidazolone-5-propionate hydrolase
GWG05_01460	ENOG41088SP	formiminoglutamate hydrolase
GWG05_01465	ENOG4105CGP	Urocanate hydratase
GWG05_01470	ENOG4105C84	Histidine ammonia-lyase
GWG05_01475	ENOG4105EWV	Sodium calcium exchanger membrane region
GWG05_01480	ENOG4107XTP	(EAL) domain protein
GWG05_01515	ENOG4105GVR	general secretion pathway protein D
GWG05_01535	ENOG4105D7Q	type ii secretion system
GWG05_01555	ENOG4106855	Competence protein
GWG05_01585	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
GWG05_01590	ENOG4105VQ7	Rod shape-determining protein MreD
GWG05_01595	ENOG4108Z03	MAF-like protein
GWG05_01600	ENOG4105C03	ribonuclease
GWG05_01605	ENOG4105QD6	exported protein
GWG05_01615	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
GWG05_01620	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
GWG05_01635	ENOG4105C5Y	PTS System
GWG05_01640	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GWG05_01655	ENOG4105CSH	Transporter
GWG05_01665	ENOG4105CGZ	zinc metallopeptidase
GWG05_01685	ENOG4105EEQ	Na H antiporter
GWG05_01690	ENOG4105C3R	Methionine synthase
GWG05_01700	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GWG05_01710	ENOG4105ETX	regulatoR
GWG05_01725	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
GWG05_01730	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
GWG05_01735	ENOG4105D06	uba thif-type nad fad binding protein
GWG05_01745	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
GWG05_01750	ENOG4105D41	biosynthesis protein thiH
GWG05_01765	ENOG4105EQK	-acetyltransferase
GWG05_01770	ENOG4108WEF	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity)
GWG05_01775	ENOG4105BZU	Histidine kinase
GWG05_01780	ENOG4108TPP	exopolysaccharide synthesis
GWG05_01795	ENOG4105N0V	mono-oxygenase ydhR
GWG05_01800	ENOG4105KVH	Transcriptional regulator
GWG05_01815	ENOG4105E0K	tonB-dependent siderophore receptor
GWG05_01830	ENOG4105CBT	Fructose-1,6-bisphosphatase
GWG05_01835	ENOG4105KRS	Proteinase inhibitor
GWG05_01840	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GWG05_01845	ENOG4105VFK	BolA family
GWG05_01855	ENOG4105E3I	toluene tolerance
GWG05_01860	ENOG4107PE3	Mammalian cell entry related domain protein
GWG05_01865	ENOG4105CY3	ABC transporter, permease
GWG05_01870	ENOG4105DHJ	ABC, transporter
GWG05_01875	ENOG4105C2X	Arabinose 5-phosphate isomerase
GWG05_01890	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
GWG05_01895	ENOG4108IUZ	ABC transporter
GWG05_01900	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GWG05_01905	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
GWG05_01910	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
GWG05_01915	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
GWG05_01920	ENOG41080Z8	PHOSPHOCARRIER protein
GWG05_01925	ENOG4105CTS	PTS system mannitol-specific
GWG05_01940	ENOG41069H0	dihydroorotase EC 3.5.2.3
GWG05_01970	ENOG4105C0H	protease
GWG05_01975	ENOG4105C0H	protease
GWG05_01985	ENOG4105D6Z	AFG1 family ATPase
GWG05_01990	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GWG05_01995	ENOG4108UJD	30S ribosomal protein S9
GWG05_02000	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GWG05_02005	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GWG05_02010	ENOG4105EIX	cytochrome c1
GWG05_02015	ENOG4107MKT	Stringent starvation protein a
GWG05_02020	ENOG4105KB2	stringent starvation protein b
GWG05_02025	ENOG4105W4M	Transport-associated protein
GWG05_02030	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GWG05_02035	ENOG41082RQ	UPF0102 protein
GWG05_02040	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
GWG05_02045	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
GWG05_02055	ENOG4108V6E	Cell division protein mraZ
GWG05_02060	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
GWG05_02065	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
GWG05_02070	ENOG4105CJN	penicillin-binding protein
GWG05_02075	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GWG05_02080	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
GWG05_02085	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
GWG05_02090	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
GWG05_02095	ENOG4105CNI	cell division protein FtsW
GWG05_02100	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
GWG05_02105	ENOG4105DFU	Cell wall formation (By similarity)
GWG05_02110	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
GWG05_02115	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
GWG05_02120	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GWG05_02125	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GWG05_02135	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GWG05_02145	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GWG05_02150	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
GWG05_02155	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
GWG05_02165	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
GWG05_02170	ENOG4105D7Q	type ii secretion system
GWG05_02175	ENOG4107QHF	type ii secretion system protein e
GWG05_02185	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
GWG05_02200	ENOG41073TP	transcriptional regulator
GWG05_02205	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
GWG05_02210	ENOG4107QSN	dihydrolipoamide acetyltransferase
GWG05_02215	ENOG4107QN2	dihydrolipoyl dehydrogenase
GWG05_02225	ENOG4108N3W	hemolysin secretion protein
GWG05_02230	ENOG4105D78	K07001 NTE family protein
GWG05_02235	ENOG4107QIJ	Aconitate hydratase 2
GWG05_02250	ENOG4105E82	cytochrome subunit of dehydrogenase
GWG05_02260	ENOG4105CKI	cobalamin synthesis protein
GWG05_02265	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GWG05_02275	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GWG05_02280	ENOG4107ZVW	dihydroneopterin aldolase
GWG05_02285	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
GWG05_02330	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GWG05_02340	ENOG4107TH8	cina domain protein
GWG05_02345	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
GWG05_02350	ENOG4105Y3E	Modulates RecA activity (By similarity)
GWG05_02355	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GWG05_02360	ENOG4105CFH	Aspartokinase
GWG05_02365	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
GWG05_02400	ENOG41061WM	D-Alanyl-D-Alanine
GWG05_02405	ENOG4106W5V	Membrane
GWG05_02415	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GWG05_02425	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GWG05_02430	ENOG4108M8S	permease YjgP YjgQ family protein
GWG05_02435	ENOG4108K5H	permease YjgP YjgQ family protein
GWG05_02455	ENOG4105BZU	Histidine kinase
GWG05_02460	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GWG05_02470	ENOG4106855	Competence protein
GWG05_02475	ENOG4105EYA	deoxyribonuclease
GWG05_02480	ENOG4105D9N	nucleoside
GWG05_02490	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
GWG05_02495	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
GWG05_02500	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
GWG05_02505	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
GWG05_02510	ENOG4105BZU	Histidine kinase
GWG05_02520	ENOG4105EAC	phosphoserine phosphatase
GWG05_02535	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GWG05_02545	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
GWG05_02550	ENOG4105K70	DNA-binding protein
GWG05_02565	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GWG05_02570	ENOG4105MYN	Zinc uptake regulation protein
GWG05_02585	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
GWG05_02590	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
GWG05_02595	ENOG4105C1J	atp-dependent rna helicase
GWG05_02600	ENOG4105D1Q	UPF0246 protein
GWG05_02605	ENOG4105CZX	twitching motility protein
GWG05_02610	ENOG4105CZX	twitching motility protein
GWG05_02615	ENOG4105DFA	alanine racemase domain protein
GWG05_02620	ENOG4105II7	pyrroline-5-carboxylate reductase
GWG05_02625	ENOG4108VIA	integral membrane protein
GWG05_02630	ENOG4105VZ9	UPF0235 protein
GWG05_02650	ENOG4105XTV	UPF0231 protein
GWG05_02655	ENOG4107VHA	regulatoR
GWG05_02660	ENOG4107QQ0	gntp family
GWG05_02665	ENOG4105BZW	Glycerate kinase
GWG05_02680	ENOG4105HEI	LysR family (Transcriptional regulator
GWG05_02685	ENOG4105D9N	nucleoside
GWG05_02695	ENOG4108YZN	class I peptide chain release factor
GWG05_02700	ENOG4108YZA	Nitrogen regulatory protein pii
GWG05_02705	ENOG4107QKW	extracellular solute-binding protein family 1
GWG05_02715	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GWG05_02720	ENOG4105EZR	dyp-type peroxidase family protein
GWG05_02725	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
GWG05_02730	ENOG4105E5Z	arginine transporter ATP-binding subunit
GWG05_02735	ENOG4106TNF	Periplasmic binding protein
GWG05_02740	ENOG4105GBT	ABC transporter
GWG05_02745	ENOG4105DMR	ABC, transporter
GWG05_02750	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GWG05_02755	ENOG4108UV7	flagellar protein motX
GWG05_02760	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GWG05_02770	ENOG4108JU6	CBS domain protein
GWG05_02775	ENOG4106KVJ	cytochrome C assembly protein
GWG05_02780	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GWG05_02785	ENOG4105K5M	30s ribosomal protein S16
GWG05_02790	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
GWG05_02795	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
GWG05_02800	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GWG05_02815	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GWG05_02820	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
GWG05_02825	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GWG05_02830	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
GWG05_02835	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GWG05_02845	ENOG41063Z6	transcriptional regulator, lysR family
GWG05_02850	ENOG41080HT	Transcriptional regulator, arsr family
GWG05_02855	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
GWG05_02860	ENOG4105CJR	Integral membrane protein (MviN
GWG05_02865	ENOG4105DTN	riboflavin biosynthesis protein ribF
GWG05_02870	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
GWG05_02875	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
GWG05_02880	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
GWG05_02885	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
GWG05_02925	ENOG4105C4K	Nad synthetase
GWG05_02930	ENOG4108YZA	Nitrogen regulatory protein pii
GWG05_02940	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
GWG05_02945	ENOG4106TD9	Diguanylate cyclase
GWG05_02950	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
GWG05_02955	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GWG05_02965	ENOG4107YB6	acetyltransferase, (GNAT) family
GWG05_02970	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GWG05_02975	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
GWG05_02980	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
GWG05_02985	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
GWG05_02990	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GWG05_02995	ENOG4105DP0	ferredoxin-NADP reductase
GWG05_03010	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
GWG05_03025	ENOG4105W39	Membrane
GWG05_03035	ENOG4105D9M	gamma-glutamylcysteine synthetase
GWG05_03040	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
GWG05_03045	ENOG4108IJ0	Aspartate ammonia-lyase
GWG05_03050	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
GWG05_03060	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GWG05_03065	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GWG05_03075	ENOG4105BZU	Histidine kinase
GWG05_03085	ENOG4105D3G	Pseudouridine synthase
GWG05_03090	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
GWG05_03120	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
GWG05_03130	ENOG4108I5D	sulfate abc transporter
GWG05_03135	ENOG4105ECW	sulfate abc transporter
GWG05_03140	ENOG4108IJ6	ABC transporter
GWG05_03145	ENOG4107R11	Transcriptional regulator
GWG05_03150	ENOG4108M1A	Chitin-binding protein
GWG05_03180	ENOG4105G0K	glycine radical enzyme YjjI family
GWG05_03185	ENOG41076CZ	activating enzyme
GWG05_03200	ENOG4105CGF	Aromatic amino acid aminotransferase
GWG05_03215	ENOG4105UTS	cellulose synthase operon protein YhjQ
GWG05_03220	ENOG4107QZ7	Cellulose synthase catalytic subunit
GWG05_03225	ENOG4107EEX	Cellulose synthase regulator protein
GWG05_03230	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
GWG05_03235	ENOG4105EJG	cellulose synthase
GWG05_03265	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
GWG05_03270	ENOG4105C1J	atp-dependent rna helicase
GWG05_03275	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
GWG05_03285	ENOG4107QSI	ABC, transporter
GWG05_03295	ENOG4106WH9	Protein of unknown function (DUF2753)
GWG05_03300	ENOG4105E39	Enoyl-CoA hydratase
GWG05_03315	ENOG4108RZ4	Short-chain dehydrogenase reductase Sdr
GWG05_03320	ENOG41083X2	DNA polymerase III, epsilon subunit
GWG05_03325	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GWG05_03330	ENOG4105C8Q	Methyl-accepting chemotaxis
GWG05_03335	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
GWG05_03340	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
GWG05_03350	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GWG05_03355	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GWG05_03365	ENOG4105KJB	cyd operon protein YbgE
GWG05_03370	ENOG4107YD3	Thioesterase
GWG05_03375	ENOG4105E02	MotA TolQ exbB proton channel
GWG05_03380	ENOG4105M8F	Biopolymer transport protein exbD tolR
GWG05_03390	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
GWG05_03395	ENOG4105KCK	Peptidoglycan-associated lipoprotein
GWG05_03400	ENOG4105UFD	tol-pal system protein YbgF
GWG05_03475	ENOG4105C8Q	Methyl-accepting chemotaxis
GWG05_03480	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
GWG05_03485	ENOG4105DSB	aldose 1-epimerase
GWG05_03495	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
GWG05_03500	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
GWG05_03510	ENOG4105E0X	reductase
GWG05_03525	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GWG05_03530	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
GWG05_03535	ENOG4105K56	Transcriptional regulator
GWG05_03550	ENOG4105EW9	transcriptional regulator AsnC family
GWG05_03565	ENOG4108K4B	hydrolase
GWG05_03580	ENOG4105C8J	)-transporter
GWG05_03585	ENOG4105C8J	)-transporter
GWG05_03600	ENOG4107SQD	Transcriptional regulator, GntR family
GWG05_03625	ENOG4108IQE	Amp-dependent synthetase and ligase
GWG05_03635	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
GWG05_03650	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
GWG05_03655	ENOG4105BZU	Histidine kinase
GWG05_03675	ENOG4105KD7	acetyltransferase
GWG05_03685	ENOG4108MJ3	acetyltransferase
GWG05_03690	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GWG05_03700	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
GWG05_03710	ENOG4105DWY	Agmatine deiminase
GWG05_03715	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
GWG05_03750	ENOG4106AXJ	AraC family transcriptional regulator
GWG05_03760	ENOG4105C1J	atp-dependent rna helicase
GWG05_03765	ENOG4105BZU	Histidine kinase
GWG05_03770	ENOG4107Y60	(LipO)protein
GWG05_03780	ENOG4106B0W	Curli production assembly transport component CsgG
GWG05_03800	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
GWG05_03810	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GWG05_03815	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
GWG05_03820	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GWG05_03825	ENOG4105E0F	Histidine kinase
GWG05_03850	ENOG4107QWG	2-Nitropropane dioxygenase
GWG05_03880	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
GWG05_03885	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GWG05_03895	ENOG4107V40	secretion protein, HlyD family
GWG05_03925	ENOG4105I93	response regulator
GWG05_03930	ENOG4105DUX	Transporter
GWG05_03935	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GWG05_03940	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
GWG05_03945	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
GWG05_03950	ENOG4105K9H	YciI-like protein
GWG05_03955	ENOG4107835	probably involved in intracellular septation (By similarity)
GWG05_03960	ENOG4105DY8	decarboxylase
GWG05_03965	ENOG4108UT2	hemolysin iii
GWG05_03970	ENOG4105D0C	transport protein
GWG05_03980	ENOG4105EV4	Multidrug resistance protein mdtH
GWG05_03990	ENOG4105D4Y	metalloprotease
GWG05_04000	ENOG4105D9U	N-acetyltransferase
GWG05_04010	ENOG4105XEP	YhcH YjgK YiaL family protein
GWG05_04020	ENOG4105CUY	Mechanosensitive ion channel
GWG05_04025	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
GWG05_04030	ENOG4105CK7	Sodium proline symporter
GWG05_04040	ENOG4108Z6Z	Transcriptional regulator
GWG05_04055	ENOG4105F2I	Transposase
GWG05_04065	ENOG4105F2I	Transposase
GWG05_04100	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
GWG05_04105	ENOG4105D6S	protein involved in catabolism of external DNA
GWG05_04115	ENOG4105C5H	ABC transporter
GWG05_04120	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GWG05_04135	ENOG4108UJV	acyl-CoA thioesterase i
GWG05_04140	ENOG4108I0Y	(ABC) transporter
GWG05_04145	ENOG4105CV6	ABC transporter, permease
GWG05_04150	ENOG4105ECP	epimerase
GWG05_04155	ENOG4105BZU	Histidine kinase
GWG05_04160	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GWG05_04165	ENOG4105IIU	Aminopeptidase
GWG05_04170	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
GWG05_04175	ENOG41090ED	Protein with unknown function (DUF469)
GWG05_04180	ENOG4105CSV	Glutaminase
GWG05_04185	ENOG4107RM6	sulfurtransferase
GWG05_04190	ENOG4105SUV	lipoprotein YgdR
GWG05_04195	ENOG4105BZ1	(ABC) transporter
GWG05_04220	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
GWG05_04225	ENOG4105BZU	Histidine kinase
GWG05_04245	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
GWG05_04250	ENOG4105DJ4	phosphatidylserine decarboxylase
GWG05_04255	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GWG05_04260	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
GWG05_04300	ENOG4105VEQ	Cold shock protein
GWG05_04310	ENOG4105C8Q	Methyl-accepting chemotaxis
GWG05_04315	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GWG05_04365	ENOG4109015	Biopolymer transport protein exbD tolR
GWG05_04385	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GWG05_04390	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
GWG05_04395	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
GWG05_04410	ENOG4108JQ7	(ABC) transporter
GWG05_04420	ENOG4105CIN	aminoacyl-histidine dipeptidase
GWG05_04430	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
GWG05_04435	ENOG4105V1F	Fermentation respiration switch protein
GWG05_04440	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
GWG05_04450	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
GWG05_04480	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GWG05_04495	ENOG4105DG7	nitrate ABC transporter
GWG05_04500	ENOG4105D7T	ABC transporter
GWG05_04505	ENOG4107QZF	nitrite reductase NADPH large subunit
GWG05_04510	ENOG4107QZF	nitrite reductase NADPH large subunit
GWG05_04515	ENOG4105DD7	kinase (PfkB family
GWG05_04520	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
GWG05_04525	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
GWG05_04550	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
GWG05_04560	ENOG4105DWK	Membrane
GWG05_04575	ENOG4108IJ7	Glycine betaine
GWG05_04580	ENOG4108HQS	Glycine betaine
GWG05_04585	ENOG4105GIJ	Glycine betaine
GWG05_04590	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
GWG05_04595	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
GWG05_04600	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
GWG05_04605	ENOG4105JAB	phenazine biosynthesis protein, phzf family
GWG05_04610	ENOG4105CRK	lysyL-tRNA synthetase
GWG05_04620	ENOG4105C8Q	Methyl-accepting chemotaxis
GWG05_04625	ENOG4105D6U	Sodium Glutamate Symporter
GWG05_04630	ENOG4105HDK	L-asparaginase
GWG05_04635	ENOG4105VUT	cytoplasmic protein
GWG05_04655	ENOG4105D07	Signal peptide peptidase, SppA
GWG05_04660	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GWG05_04665	ENOG41069NU	Nitroreductase
GWG05_04670	ENOG4105C8Q	Methyl-accepting chemotaxis
GWG05_04675	ENOG4108UW5	maltose o-acetyltransferase
GWG05_04680	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GWG05_04685	ENOG4105CIS	alcohol dehydrogenase
GWG05_04690	ENOG4105HEI	LysR family (Transcriptional regulator
GWG05_04695	ENOG4105CI1	PTS System
GWG05_04700	ENOG4108IA2	Sodium pantothenate symporter
GWG05_04705	ENOG4105RG0	Membrane
GWG05_04710	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GWG05_04715	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
GWG05_04720	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
GWG05_04725	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GWG05_04740	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
GWG05_04750	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GWG05_04760	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
GWG05_04765	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GWG05_04780	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
GWG05_04785	ENOG4107YIM	Involved in the transcription termination process (By similarity)
GWG05_04790	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
GWG05_04795	ENOG4108ZAI	phosphatidylglycerophosphatase a
GWG05_04800	ENOG4108JQ6	ABC transporter
GWG05_04810	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GWG05_04815	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GWG05_04820	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
GWG05_04825	ENOG4105CTB	Polyprenyl synthetase
GWG05_04830	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GWG05_04835	ENOG4105E14	MotA TolQ exbB proton channel
GWG05_04840	ENOG4107XSU	flagellar motor protein motb
GWG05_04845	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GWG05_04855	ENOG4105HBR	Rna-binding protein
GWG05_04860	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
GWG05_04865	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GWG05_04870	ENOG4105EEI	dihydropteroate synthase
GWG05_04875	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GWG05_04880	ENOG4105CP7	Triose-phosphate isomerase
GWG05_04885	ENOG4105NTZ	Preprotein translocase subunit SecG
GWG05_04900	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
GWG05_04905	ENOG4105CHV	Transcription elongation factor NusA
GWG05_04910	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
GWG05_04915	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GWG05_04920	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GWG05_04925	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GWG05_04930	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GWG05_04935	ENOG4105E5W	Transporter
GWG05_04940	ENOG41090EX	DsrE family
GWG05_04945	ENOG4105WAY	exported protein
GWG05_04950	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
GWG05_04955	ENOG4105CFP	Peptidase U32
GWG05_04960	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
GWG05_04990	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
GWG05_04995	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GWG05_05000	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
GWG05_05010	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
GWG05_05015	ENOG4107SWG	transcriptional regulator MERR family
GWG05_05030	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GWG05_05040	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
GWG05_05045	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
GWG05_05050	ENOG4108Z43	UPF0250 protein
GWG05_05055	ENOG4105DZ1	carboxypeptidase
GWG05_05060	ENOG4105K6T	rare lipoprotein A
GWG05_05065	ENOG4105CVE	Lytic murein transglycosylase
GWG05_05070	ENOG4105CNI	cell division protein FtsW
GWG05_05075	ENOG4105CJN	penicillin-binding protein
GWG05_05080	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
GWG05_05085	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
GWG05_05090	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
GWG05_05110	ENOG4105C8T	Leucyl-tRNA synthetase
GWG05_05115	ENOG4107PAI	alpha helical protein
GWG05_05120	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
GWG05_05125	ENOG4108JU5	Magnesium and cobalt efflux protein
GWG05_05130	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
GWG05_05135	ENOG4105C9A	Phoh family
GWG05_05140	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GWG05_05145	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GWG05_05150	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
GWG05_05155	ENOG4105VEQ	Cold shock protein
GWG05_05170	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
GWG05_05175	ENOG4105BZU	Histidine kinase
GWG05_05185	ENOG4108KHX	Diguanylate cyclase
GWG05_05195	ENOG4105C5I	Dehydrogenase
GWG05_05210	ENOG4105D01	(LipO)protein
GWG05_05215	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
GWG05_05220	ENOG4108UMI	ABC transporter, permease
GWG05_05225	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GWG05_05235	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GWG05_05240	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GWG05_05245	ENOG4105DHQ	Histidine kinase
GWG05_05250	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GWG05_05260	ENOG4108IXY	short-chain dehydrogenase reductase
GWG05_05280	ENOG4106371	Methyltransferase
GWG05_05285	ENOG4105T0Z	Conserved Protein
GWG05_05300	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
GWG05_05305	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
GWG05_05310	ENOG4105E33	succinate dehydrogenase
GWG05_05320	ENOG4105C8Q	Methyl-accepting chemotaxis
GWG05_05325	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
GWG05_05330	ENOG4105EGS	Mechanosensitive ion channel
GWG05_05340	ENOG4105DR5	peptidase
GWG05_05355	ENOG4105EJC	lysr family transcriptional regulator
GWG05_05370	ENOG4105C5Q	Transcriptional regulator
GWG05_05375	ENOG4108JQC	penicillin-binding protein 1A
GWG05_05400	ENOG4105E4G	Type IV pilus
GWG05_05405	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GWG05_05410	ENOG4105D49	3-dehydroquinate synthase
GWG05_05420	ENOG4105DFE	Dna adenine methylase
GWG05_05425	ENOG4105DJV	ribulose-phosphate 3-epimerase
GWG05_05430	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GWG05_05435	ENOG4105C31	Tryptophanyl-tRNA synthetase
GWG05_05450	ENOG4105C8Y	Acetylornithine aminotransferase
GWG05_05455	ENOG4105F4X	arginine
GWG05_05460	ENOG4105C26	Dehydrogenase
GWG05_05495	ENOG4107VXZ	Hydrolase
GWG05_05515	ENOG41060QA	UPF0267 protein
GWG05_05520	ENOG4107QWE	)-transporter
GWG05_05565	ENOG4105C3G	gtp-binding protein
GWG05_05570	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
GWG05_05575	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GWG05_05585	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
GWG05_05590	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
GWG05_05595	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
GWG05_05600	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GWG05_05605	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GWG05_05615	ENOG41063JG	Transcriptional regulator
GWG05_05620	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
GWG05_05625	ENOG4105CK2	sodium dicarboxylate symporter
GWG05_05630	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
GWG05_05635	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
GWG05_05650	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GWG05_05655	ENOG4105BZG	amino acid carrier protein
GWG05_05660	ENOG41066YJ	Beta-lactamase
GWG05_05670	ENOG4105G2Y	Transcriptional regulator
GWG05_05675	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GWG05_05685	ENOG4105D7Z	glutathione synthase
GWG05_05690	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
GWG05_05700	ENOG4105GPY	SprT protein
GWG05_05705	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GWG05_05710	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GWG05_05725	ENOG4105KME	endoribonuclease L-psp
GWG05_05740	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
GWG05_05745	ENOG4105DR5	peptidase
GWG05_05750	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GWG05_05755	ENOG4107WCA	isomerase
GWG05_05765	ENOG4108V1U	phospholipid-binding protein
GWG05_05770	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GWG05_05785	ENOG4105C87	Aminotransferase class I and II
GWG05_05795	ENOG4105C5Q	Transcriptional regulator
GWG05_05800	ENOG4105UBK	short-chain dehydrogenase reductase
GWG05_05805	ENOG4105ERU	peptidase
GWG05_05810	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
GWG05_05815	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GWG05_05825	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
GWG05_05830	ENOG4105E2D	ec 3.2.1.52
GWG05_05835	ENOG4105RD7	BadF BadG BcrA BcrD
GWG05_05845	ENOG4108JQ7	(ABC) transporter
GWG05_05855	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GWG05_05870	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
GWG05_05875	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GWG05_05880	ENOG41085FC	arsR family transcriptional regulator
GWG05_05885	ENOG4105D6J	arsenicaL-resistance protein
GWG05_05890	ENOG4105K89	arsenate reductase
GWG05_05905	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
GWG05_05910	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
GWG05_05915	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GWG05_05925	ENOG4108JIR	Flagellum-specific ATP synthase
GWG05_05945	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GWG05_05950	ENOG4105DD5	Flagellar motor switch protein
GWG05_05955	ENOG4105VTB	flagellar biosynthesis protein fliO
GWG05_05960	ENOG4105CN7	Flagellar biosynthetic protein FliP
GWG05_05965	ENOG4105VS8	Flagellar biosynthetic protein fliq
GWG05_05970	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
GWG05_05975	ENOG4105D00	flagellar biosynthetic protein flhB
GWG05_05980	ENOG4105D7B	Flagellar biosynthesis protein flha
GWG05_05985	ENOG4105FZW	flagellar biosynthesis regulator FlhF
GWG05_05995	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GWG05_06000	ENOG4108VYJ	response regulator receiver protein
GWG05_06005	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
GWG05_06015	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GWG05_06020	ENOG4105E14	MotA TolQ exbB proton channel
GWG05_06025	ENOG4108SEK	ompa motb domain protein
GWG05_06030	ENOG4107QJE	Chromosome Partitioning Protein
GWG05_06040	ENOG4108V3W	Chemotaxis protein, CheW
GWG05_06055	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
GWG05_06060	ENOG41060IM	Heme exporter protein
GWG05_06065	ENOG4105X3C	heme exporter protein
GWG05_06070	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
GWG05_06075	ENOG4105DA4	cytochrome c-type biogenesis protein
GWG05_06080	ENOG4107QX9	Thiol disulfide interChange protein
GWG05_06085	ENOG4105KWW	Biogenesis protein
GWG05_06090	ENOG4108QUE	repeat-containing protein
GWG05_06095	ENOG410903C	(LipO)protein
GWG05_06100	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GWG05_06105	ENOG4105M2J	Glutaredoxin
GWG05_06125	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
GWG05_06155	ENOG4108YYD	acetyltransferase
GWG05_06170	ENOG4108UHU	Aldolase
GWG05_06175	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
GWG05_06180	ENOG4105P66	Membrane
GWG05_06185	ENOG4105CTX	dehydratase
GWG05_06190	ENOG4107QZW	Altronate oxidoreductase
GWG05_06200	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
GWG05_06210	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GWG05_06225	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
GWG05_06230	ENOG4108Z1B	Cyclase dehydrase
GWG05_06235	ENOG4105VDB	UPF0125 protein
GWG05_06240	ENOG4105K4T	epimerase
GWG05_06245	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GWG05_06255	ENOG4105M7P	phage repressor
GWG05_06360	ENOG4108Z6H	mu-like prophage Flumu protein gp27
GWG05_06365	ENOG4105CF2	Mu-like prophage FluMu protein GP28
GWG05_06370	ENOG4105QIB	mu-like prophage Flumu protein gp29
GWG05_06395	ENOG4108TVE	i protein
GWG05_06400	ENOG4105EFV	Major head subunit
GWG05_06485	ENOG4107SXA	Phosphorylase
GWG05_06490	ENOG4105D3G	Pseudouridine synthase
GWG05_06495	ENOG4105DU0	nucleoside hydrolase
GWG05_06510	ENOG4105RX8	Protein of unknown function (DUF1523)
GWG05_06515	ENOG4108NVR	Methyl-accepting chemotaxis
GWG05_06520	ENOG410829K	Lysine exporter protein (Lyse ygga)
GWG05_06530	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
GWG05_06545	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GWG05_06550	ENOG4105KUZ	arsenate reductase
GWG05_06560	ENOG4105CEE	C4-dicarboxylate transporter
GWG05_06575	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
GWG05_06580	ENOG4105C5S	asparaginyl-tRNA synthetase
GWG05_06600	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
GWG05_06605	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GWG05_06610	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
GWG05_06615	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
GWG05_06620	ENOG4105D0M	Protease HtpX homolog
GWG05_06625	ENOG4105QVC	MOSC domain-containing protein
GWG05_06625	ENOG4105QVC	MOSC domain-containing protein
GWG05_06635	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
GWG05_06640	ENOG4105Z2P	Protein of unknown function (DUF465)
GWG05_06650	ENOG4105UQX	Mate efflux family protein
GWG05_06670	ENOG4105C6T	cysteine synthase
GWG05_06675	ENOG4105C0A	alcohol dehydrogenase
GWG05_06685	ENOG4107Z3H	Transcriptional regulator, TetR family
GWG05_06690	ENOG4107RGH	Aldehyde dehydrogenase
GWG05_06700	ENOG4108QBX	(LipO)protein
GWG05_06705	ENOG4105C5Q	Transcriptional regulator
GWG05_06725	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
GWG05_06730	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
GWG05_06735	ENOG41081XQ	Conserved Protein
GWG05_06745	ENOG4105C9M	aspartyl-trna synthetase
GWG05_06750	ENOG4105CDY	transcriptional regulatory protein
GWG05_06755	ENOG4105DIJ	Phosphoethanolamine transferase
GWG05_06760	ENOG4105E2R	ROK family
GWG05_06765	ENOG4105CE4	GlcNAc 6-P deacetylase
GWG05_06770	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GWG05_06775	ENOG4105CI1	PTS System
GWG05_06780	ENOG4105E2D	ec 3.2.1.52
GWG05_06785	ENOG4105CX6	glutaminyL-tRNA synthetase
GWG05_06790	ENOG41090R7	Ferric uptake
GWG05_06800	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
GWG05_06805	ENOG4105NNH	LexA regulated protein
GWG05_06815	ENOG4105EV9	Alpha Beta Hydrolase
GWG05_06820	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
GWG05_06825	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
GWG05_06835	ENOG41090MY	MarR family Transcriptional regulator
GWG05_06840	ENOG4105CVE	Lytic murein transglycosylase
GWG05_06845	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
GWG05_06850	ENOG4108VGW	abc transporter atp-binding protein
GWG05_06860	ENOG4105VNH	ABC transporter solute-binding protein
GWG05_06870	ENOG4107ZN8	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
GWG05_06880	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
GWG05_06890	ENOG4105CFU	surface antigen
GWG05_06895	ENOG4105MA0	exported protein
GWG05_06910	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
GWG05_06915	ENOG4105BZU	Histidine kinase
GWG05_06920	ENOG4107SC1	transglycosylase
GWG05_06925	ENOG41060NJ	transcriptional regulator
GWG05_06935	ENOG4105NAU	thioesterase Superfamily protein
GWG05_06950	ENOG4105E9H	Lytic Murein transglycosylase
GWG05_06955	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
GWG05_06960	ENOG4105D1A	Methyltransferase
GWG05_06965	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GWG05_06975	ENOG4105F2I	Transposase
GWG05_07005	ENOG4105F5W	AtP-binding protein
GWG05_07010	ENOG4105D70	Integrase catalytic subunit
GWG05_07030	ENOG4108YX2	DNA-binding protein
GWG05_07050	ENOG4105CHH	sulfate transporter
GWG05_07060	ENOG4105BZU	Histidine kinase
GWG05_07065	ENOG4105F2I	Transposase
GWG05_07070	ENOG4105EZE	Cupin 4 family protein
GWG05_07095	ENOG4105F5W	AtP-binding protein
GWG05_07180	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GWG05_07185	ENOG4107RZZ	dna polymerase iii epsilon subunit
GWG05_07200	ENOG4107QPN	acyl-Coa dehydrogenase
GWG05_07205	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GWG05_07210	ENOG4105E7A	Glutamine amidotransferase
GWG05_07220	ENOG4105CHW	UPF0052 protein
GWG05_07230	ENOG4105BZU	Histidine kinase
GWG05_07245	ENOG4105WH1	Two component transcriptional regulator luxr family
GWG05_07250	ENOG4105BZU	Histidine kinase
GWG05_07255	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GWG05_07260	ENOG4108ZNS	ferredoxin-type protein NapF
GWG05_07270	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
GWG05_07275	ENOG4108BGM	Quinol dehydrogenase periplasmic component
GWG05_07280	ENOG4105GXZ	Ferredoxin-type protein NapH
GWG05_07290	ENOG4105CUW	cytochrome C-TYPE protein
GWG05_07295	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
GWG05_07300	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GWG05_07305	ENOG4105M00	molybdopterin converting factor, subunit 1
GWG05_07310	ENOG4108ZAF	Molybdopterin
GWG05_07315	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
GWG05_07320	ENOG4105E0C	molybdate abc transporter
GWG05_07325	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
GWG05_07330	ENOG410832A	alpha/beta hydrolase fold
GWG05_07335	ENOG4105D06	uba thif-type nad fad binding protein
GWG05_07340	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
GWG05_07345	ENOG4105EUJ	GTP cyclohydrolase i
GWG05_07350	ENOG4105C8Q	Methyl-accepting chemotaxis
GWG05_07365	ENOG4105CC0	LysR family Transcriptional regulator
GWG05_07370	ENOG4108YYC	ycei family
GWG05_07395	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GWG05_07400	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
GWG05_07415	ENOG4105BZU	Histidine kinase
GWG05_07470	ENOG4105D82	Glutamate dehydrogenase
GWG05_07475	ENOG4105FE9	pseudouridine synthase
GWG05_07480	ENOG4105DJ2	Major Facilitator Superfamily
GWG05_07490	ENOG4105C5Q	Transcriptional regulator
GWG05_07500	ENOG4106428	Protein of unknown function (DUF2496)
GWG05_07510	ENOG4108Q2J	Inner membrane protein YebE
GWG05_07520	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GWG05_07525	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GWG05_07530	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GWG05_07540	ENOG4105F27	Major Facilitator
GWG05_07545	ENOG4105CV8	reductase
GWG05_07565	ENOG4105HEI	LysR family (Transcriptional regulator
GWG05_07570	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
GWG05_07575	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GWG05_07580	ENOG4105CXY	transporter
GWG05_07585	ENOG4105E98	transcriptional regulator DeoR family
GWG05_07590	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
GWG05_07595	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
GWG05_07600	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GWG05_07615	ENOG4108WFC	UPF0438 protein yifE
GWG05_07620	ENOG4108QSZ	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity)
GWG05_07640	ENOG4105CUG	Oligopeptidase b
GWG05_07645	ENOG4105D05	Receptor
GWG05_07650	ENOG4105E68	Sulfatase
GWG05_07655	ENOG4105PAN	UPF0352 protein
GWG05_07660	ENOG4106V8H	Nucleoid-associated protein
GWG05_07665	ENOG4107FKK	extracellular solute-binding protein family 1
GWG05_07670	ENOG4105D56	permease protein
GWG05_07680	ENOG4108IJ9	(ABC) transporter
GWG05_07685	ENOG4105CSR	polyphosphate kinase 2
GWG05_07690	ENOG4108KDQ	Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons (By similarity)
GWG05_07705	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
GWG05_07710	ENOG4105ERG	peptidase m48, ste24p
GWG05_07720	ENOG4105K89	arsenate reductase
GWG05_07735	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
GWG05_07745	ENOG4106PMH	Extracellular solute-binding protein family 3
GWG05_07750	ENOG4105DYB	Isoaspartyl dipeptidase
GWG05_07755	ENOG4105DWU	Membrane
GWG05_07760	ENOG4108JEH	abc transporter atp-binding protein
GWG05_07765	ENOG4106PMH	Extracellular solute-binding protein family 3
GWG05_07770	ENOG4105DSP	amino acid AbC transporter
GWG05_07775	ENOG4106YG3	ABC transporter
GWG05_07785	ENOG4105F1A	Pyruvate formate-lyase
GWG05_07790	ENOG4105BZU	Histidine kinase
GWG05_07795	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
GWG05_07800	ENOG4105IPI	Membrane
GWG05_07805	ENOG4105DN3	alpha-2-macroglobulin domain protein
GWG05_07810	ENOG4108JQB	penicillin-binding protein 1C
GWG05_07820	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
GWG05_07830	ENOG4105EN6	Membrane
GWG05_07845	ENOG41063QE	flagellar protein FlaG
GWG05_07855	ENOG4105MQ3	flagellar protein FliS
GWG05_07880	ENOG4105D2T	synthase
GWG05_07890	ENOG4105F0R	Cytidylyltransferase
GWG05_07905	ENOG4105CHR	reductase
GWG05_07910	ENOG4105CEY	Amp-dependent synthetase and ligase
GWG05_07925	ENOG4105K64	Glycosyl transferase, family 2
GWG05_07945	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GWG05_07960	ENOG4107WZ3	Transferase
GWG05_07990	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GWG05_07995	ENOG4105C5E	polysaccharide biosynthesis protein
GWG05_08000	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
GWG05_08010	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
GWG05_08025	ENOG4108UYE	Lactoylglutathione lyase
GWG05_08030	ENOG4105CSM	endonuclease III
GWG05_08040	ENOG4108UQQ	Electron transport complex
GWG05_08045	ENOG4105D6A	Electron transport complex
GWG05_08055	ENOG4108R3D	Electron transport complex
GWG05_08060	ENOG4105DGN	Electron transport complex
GWG05_08065	ENOG4105D7V	transposase
GWG05_08075	ENOG4108PCN	EamA-like transporter family
GWG05_08085	ENOG4107SDU	Methyl-accepting chemotaxis
GWG05_08095	ENOG4105RKW	reductase (By
GWG05_08100	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
GWG05_08105	ENOG4105CHM	Aminotransferase
GWG05_08115	ENOG41090BQ	Glutaredoxin
GWG05_08120	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
GWG05_08125	ENOG4105CFI	type iii restriction protein res subunit
GWG05_08130	ENOG4105EFX	secretion protein, HlyD family
GWG05_08135	ENOG4105KK7	inner membrane protein YiaW
GWG05_08145	ENOG4108NEV	two component transcriptional regulator, LytTR family
GWG05_08150	ENOG4108HRK	Histidine kinase
GWG05_08155	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GWG05_08160	ENOG4105C0A	alcohol dehydrogenase
GWG05_08165	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
GWG05_08170	ENOG4107QSI	ABC, transporter
GWG05_08175	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GWG05_08180	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GWG05_08185	ENOG4105C3U	ABC transporter
GWG05_08190	ENOG4108JQ7	(ABC) transporter
GWG05_08195	ENOG4105DU1	integral membrane protein, terc
GWG05_08200	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GWG05_08210	ENOG4107QJT	sodium dicarboxylate symporter
GWG05_08230	ENOG4105CD3	dihydroorotase
GWG05_08240	ENOG4108NVR	Methyl-accepting chemotaxis
GWG05_08245	ENOG4105K59	histidine triad (HIT) protein
GWG05_08280	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GWG05_08285	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GWG05_08290	ENOG4107SDU	Methyl-accepting chemotaxis
GWG05_08300	ENOG4105CKW	Inner membrane protein yedI
GWG05_08305	ENOG4105DPN	Oligoendopeptidase f
GWG05_08310	ENOG4105DPN	Oligoendopeptidase f
GWG05_08315	ENOG4105D0Y	UPF0227 protein
GWG05_08320	ENOG4105CEP	NADH dehydrogenase
GWG05_08325	ENOG4105K8R	UPF0145 protein
GWG05_08330	ENOG4107T7U	Sulfatase
GWG05_08340	ENOG4105CFH	Aspartokinase
GWG05_08345	ENOG4107QZM	n-acetylglutamate synthase
GWG05_08350	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GWG05_08375	ENOG4105CR8	Transcriptional regulator
GWG05_08380	ENOG4105DAA	L-lactate
GWG05_08385	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
GWG05_08390	ENOG4107QR9	Iron-sulfur cluster binding protein
GWG05_08395	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
GWG05_08415	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GWG05_08435	ENOG4105C2C	drug resistance transporter, Bcr CflA
GWG05_08510	ENOG4105CHH	sulfate transporter
GWG05_08530	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
GWG05_08535	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
GWG05_08540	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GWG05_08545	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
GWG05_08550	ENOG4105WJG	Glutathione
GWG05_08555	ENOG4107RE1	Inosine-guanosine kinase
GWG05_08560	ENOG4105C8Q	Methyl-accepting chemotaxis
GWG05_08575	ENOG4105BZU	Histidine kinase
GWG05_08590	ENOG4105F3T	(LipO)protein
GWG05_08600	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
GWG05_08605	ENOG4105WQI	isochorismatase
GWG05_08610	ENOG4105CEY	Amp-dependent synthetase and ligase
GWG05_08615	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
GWG05_08625	ENOG4105CEY	Amp-dependent synthetase and ligase
GWG05_08630	ENOG4105J76	Periplasmic binding protein
GWG05_08635	ENOG4108TSE	Transferase
GWG05_08640	ENOG4105E0A	ABC, transporter
GWG05_08645	ENOG4105TVJ	transport system, permease
GWG05_08650	ENOG4105DQ5	transport system permease protein
GWG05_08655	ENOG4105D05	Receptor
GWG05_08670	ENOG4105QZU	Inner membrane protein YfeZ
GWG05_08680	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
GWG05_08685	ENOG4105BZJ	Electron transfer flavoprotein
GWG05_08690	ENOG4105C10	Electron transfer flavoprotein
GWG05_08695	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
GWG05_08700	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
GWG05_08705	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GWG05_08710	ENOG4105EE5	Membrane protein terC
GWG05_08720	ENOG4105MH2	YfcL protein
GWG05_08725	ENOG4108IQE	Amp-dependent synthetase and ligase
GWG05_08730	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
GWG05_08735	ENOG41067MG	lrgb family
GWG05_08740	ENOG4105VAW	lrga family
GWG05_08745	ENOG4107R49	K07407 alpha-galactosidase EC 3.2.1.22
GWG05_08755	ENOG4105CJB	Exodeoxyribonuclease I
GWG05_08760	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
GWG05_08765	ENOG4105FF5	Membrane
GWG05_08785	ENOG4105CHM	Aminotransferase
GWG05_08790	ENOG4105ETT	transcriptional Regulator, LysR family
GWG05_08795	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
GWG05_08805	ENOG4105EF1	ribulokinase
GWG05_08810	ENOG4105DMK	Periplasmic binding protein LacI transcriptional regulator
GWG05_08815	ENOG4105C2J	ABC transporter
GWG05_08820	ENOG4105CNN	ABC, transporter
GWG05_08830	ENOG4105YK5	50S ribosomal protein L36
GWG05_08835	ENOG4105NRA	50s ribosomal protein l31 type b
GWG05_08850	ENOG4108VKG	metal-dependent hydrolase
GWG05_08865	ENOG4105CEE	C4-dicarboxylate transporter
GWG05_08875	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
GWG05_08880	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GWG05_08895	ENOG4105BZN	citrate synthase
GWG05_08900	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
GWG05_08905	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
GWG05_08910	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
GWG05_08915	ENOG4105E33	succinate dehydrogenase
GWG05_08920	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
GWG05_08925	ENOG4105C7S	Dehydrogenase
GWG05_08930	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
GWG05_08935	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
GWG05_08960	ENOG4105C6N	Formate acetyltransferase
GWG05_08965	ENOG4105TMB	Formate nitrite transporter
GWG05_08970	ENOG4105DDY	UPF0142 protein ycaO
GWG05_08980	ENOG4105KPY	Small multidrug resistance protein
GWG05_08985	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GWG05_08990	ENOG4105VEQ	Cold shock protein
GWG05_08995	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
GWG05_09000	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GWG05_09005	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GWG05_09010	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
GWG05_09015	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
GWG05_09020	ENOG4107MBR	17 kDa surface antigen
GWG05_09025	ENOG4105BZU	Histidine kinase
GWG05_09030	ENOG4105C3M	thioredoxin reductase
GWG05_09035	ENOG4105DCF	alanine dehydrogenase
GWG05_09040	ENOG4105EW9	transcriptional regulator AsnC family
GWG05_09045	ENOG4105CNU	cell division protein FtsK
GWG05_09050	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
GWG05_09055	ENOG4105D1H	recombination factor protein RarA
GWG05_09060	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GWG05_09065	ENOG4105E96	Colicin v production protein
GWG05_09070	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
GWG05_09075	ENOG4105CS2	ec 3.2.1.21
GWG05_09080	ENOG4105C5Y	PTS System
GWG05_09085	ENOG4105DDV	Transcriptional regulator (LacI family
GWG05_09090	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
GWG05_09095	ENOG4108JQ2	peptide transport system atp-binding protein
GWG05_09100	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
GWG05_09105	ENOG4108EU3	peptide transport system, permease
GWG05_09110	ENOG4108EKA	peptide transport system, permease
GWG05_09115	ENOG4108J59	Extracellular solute-binding protein, family 5
GWG05_09120	ENOG4105E51	psp operon transcriptional activator
GWG05_09125	ENOG41087YS	Phage shock protein A
GWG05_09130	ENOG4105YYT	phage shock protein B
GWG05_09140	ENOG4105CM6	amino acid regulated cytosolic protein
GWG05_09145	ENOG4106K28	UPF0283 membrane protein
GWG05_09150	ENOG4105MIR	Phenylalanine 4-monooxygenase
GWG05_09155	ENOG41090A4	Pterin carbinolamine dehydratase
GWG05_09165	ENOG4108WS1	
GWG05_09170	ENOG4105BZU	Histidine kinase
GWG05_09175	ENOG41090EK	ompa motb domain protein
GWG05_09180	ENOG4105D4P	Coproporphyrinogen iii oxidase
GWG05_09185	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GWG05_09195	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
GWG05_09205	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GWG05_09210	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GWG05_09220	ENOG4105F2I	Transposase
GWG05_09225	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GWG05_09245	ENOG41082F9	transcriptional regulator
GWG05_09255	ENOG4105FQ6	thiopurine methyltransferase
GWG05_09260	ENOG4107QXK	peptidase
GWG05_09265	ENOG4108BY2	phosphohistidine phosphatase
GWG05_09275	ENOG4108IPJ	Membrane
GWG05_09280	ENOG4107QSI	ABC, transporter
GWG05_09290	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GWG05_09295	ENOG4108JA2	transcriptioN-repair coupling factor
GWG05_09305	ENOG4105D60	lipoprotein releasing system transmembrane protein
GWG05_09310	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GWG05_09315	ENOG4105D60	lipoprotein releasing system transmembrane protein
GWG05_09330	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
GWG05_09335	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GWG05_09340	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
GWG05_09345	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
GWG05_09350	ENOG4105K70	DNA-binding protein
GWG05_09355	ENOG4105EIN	peptidylprolyl cis-trans isomerase
GWG05_09360	ENOG4105C5H	ABC transporter
GWG05_09365	ENOG4107QN1	sodium solute
GWG05_09370	ENOG41062QD	Membrane
GWG05_09385	ENOG41060WC	Enoyl-CoA hydratase
GWG05_09390	ENOG4105BZG	amino acid carrier protein
GWG05_09400	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
GWG05_09405	ENOG4106HK8	GPR1 FUN34 yaaH family protein
GWG05_09430	ENOG4105E39	Enoyl-CoA hydratase
GWG05_09435	ENOG4107QX3	carboxylase
GWG05_09440	ENOG4105C1G	acyl-Coa dehydrogenase
GWG05_09445	ENOG4105C26	Dehydrogenase
GWG05_09450	ENOG4105C1G	acyl-Coa dehydrogenase
GWG05_09455	ENOG4105E39	Enoyl-CoA hydratase
GWG05_09460	ENOG4105E39	Enoyl-CoA hydratase
GWG05_09465	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GWG05_09475	ENOG4105D5Q	Arginine ornithine antiporter
GWG05_09480	ENOG4105HF0	Membrane
GWG05_09560	ENOG41062B0	ABC transporter, permease
GWG05_09565	ENOG4107R9N	ABC transporter
GWG05_09570	ENOG4105C2J	ABC transporter
GWG05_09575	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
GWG05_09580	ENOG4105DND	Transcriptional regulator
GWG05_09595	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
GWG05_09600	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
GWG05_09610	ENOG4108KB2	LysR family Transcriptional regulator
GWG05_09615	ENOG4105CS2	ec 3.2.1.21
GWG05_09620	ENOG4105CHR	reductase
GWG05_09625	ENOG4105CBN	LysR family transcriptional regulator
GWG05_09640	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
GWG05_09650	ENOG4105DUM	transcriptional regulator, lysR family
GWG05_09660	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
GWG05_09665	ENOG4105D1S	lipid A biosynthesis
GWG05_09675	ENOG4105EUB	pirin domain protein
GWG05_09680	ENOG4105CQ2	DNA polymerase
GWG05_09710	ENOG4107QI1	Mate efflux family protein
GWG05_09715	ENOG4105W1I	UPF0253 protein
GWG05_09720	ENOG4108R6K	riboflavin synthase, subunit alpha
GWG05_09735	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
GWG05_09740	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
GWG05_09775	ENOG4105D7V	transposase
GWG05_09780	ENOG4105QNR	S1 RNA binding domain protein
GWG05_09790	ENOG4105XW2	UPF0263 protein
GWG05_09795	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
GWG05_09800	ENOG4108W5H	UPF0263 protein
GWG05_09805	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
GWG05_09810	ENOG4107QMS	site-determining protein
GWG05_09815	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
GWG05_09820	ENOG4105VNG	YcgL domain-containing protein
GWG05_09825	ENOG4105CVE	Lytic murein transglycosylase
GWG05_09830	ENOG4105EJQ	L-serine dehydratase
GWG05_09835	ENOG4105EJQ	L-serine dehydratase
GWG05_09840	ENOG4105NBK	UPF0345 protein
GWG05_09845	ENOG4105CK2	sodium dicarboxylate symporter
GWG05_09855	ENOG4105CHU	acetyl-coa acetyltransferase
GWG05_09860	ENOG4105D58	Diguanylate phosphodiesterase
GWG05_09865	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GWG05_09870	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GWG05_09910	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GWG05_09915	ENOG4105CHU	acetyl-coa acetyltransferase
GWG05_09920	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GWG05_09930	ENOG4108VWS	Yaeq family
GWG05_09950	ENOG4105EHG	Permease protein
GWG05_09965	ENOG4107MBR	17 kDa surface antigen
GWG05_09970	ENOG4105CEY	Amp-dependent synthetase and ligase
GWG05_09990	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
GWG05_09995	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
GWG05_10000	ENOG4105BZU	Histidine kinase
GWG05_10010	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GWG05_10015	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
GWG05_10020	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
GWG05_10030	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GWG05_10035	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
GWG05_10040	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GWG05_10050	ENOG4105DVT	helicase
GWG05_10055	ENOG41072GX	Peptidase M22 Glycoprotease
GWG05_10065	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GWG05_10070	ENOG4105CEY	Amp-dependent synthetase and ligase
GWG05_10085	ENOG4105DXC	membrane
GWG05_10095	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
GWG05_10100	ENOG4105WD1	Membrane
GWG05_10105	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GWG05_10110	ENOG4107QMP	dna polymerase iii subunits gamma and tau
GWG05_10115	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
GWG05_10120	ENOG4105CR8	Transcriptional regulator
GWG05_10125	ENOG4105EUB	pirin domain protein
GWG05_10130	ENOG4105DWD	nucleoside recognition domain protein
GWG05_10180	ENOG4108BUD	transposase
GWG05_10185	ENOG4105WH1	Two component transcriptional regulator luxr family
GWG05_10195	ENOG4105CQ7	ATP-dependent helicase
GWG05_10205	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
GWG05_10220	ENOG4105C5X	domain protein
GWG05_10225	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
GWG05_10230	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
GWG05_10235	ENOG4105FAT	Acyl-transferase
GWG05_10245	ENOG4105DR4	Methyltransferase
GWG05_10250	ENOG4108N3W	hemolysin secretion protein
GWG05_10255	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
GWG05_10265	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GWG05_10270	ENOG4105D1F	ATP-binding protein
GWG05_10275	ENOG4105DBI	uridine monophosphokinase
GWG05_10280	ENOG4105DHP	deoxycytidine triphosphate deaminase
GWG05_10285	ENOG4105CJ3	phosphate transporter
GWG05_10290	ENOG4105C03	ribonuclease
GWG05_10295	ENOG4105EI2	Pseudouridine synthase
GWG05_10300	ENOG4108UHJ	MAF-like protein
GWG05_10310	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
GWG05_10315	ENOG4105VGS	50s ribosomal protein l32
GWG05_10320	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
GWG05_10325	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GWG05_10330	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GWG05_10335	ENOG4105CHR	reductase
GWG05_10340	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GWG05_10345	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GWG05_10350	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
GWG05_10355	ENOG4105HHA	aminodeoxychorismate lyase
GWG05_10360	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
GWG05_10365	ENOG4107QRG	dna polymerase iii
GWG05_10370	ENOG4105F8V	Hydrolase, tatD family
GWG05_10435	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GWG05_10440	ENOG4105DY2	Paraquat-inducible protein b
GWG05_10445	ENOG4105H2K	paraquat-inducible protein a
GWG05_10455	ENOG4105X2V	dna damage-inducible protein
GWG05_10480	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
GWG05_10500	ENOG4106NZI	LysR family Transcriptional regulator
GWG05_10525	ENOG4108ZIT	Ferredoxin, 2FE-2S
GWG05_10540	ENOG4105KTU	Transcriptional regulator, arsr family
GWG05_10545	ENOG4107Y80	Major Facilitator superfamily
GWG05_10555	ENOG4105PGM	cation diffusion facilitator family transporter
GWG05_10560	ENOG4107YCR	Transcriptional regulator, ARSR family
GWG05_10570	ENOG4105F5W	AtP-binding protein
GWG05_10575	ENOG4105D70	Integrase catalytic subunit
GWG05_10630	ENOG4108Z3N	Transcriptional regulator
GWG05_10645	ENOG4105W1Y	Transcriptional regulator
GWG05_10670	ENOG4105DAN	ATP-dependent protease
GWG05_10675	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
GWG05_10680	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
GWG05_10690	ENOG4105C5H	ABC transporter
GWG05_10700	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
GWG05_10705	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
GWG05_10710	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
GWG05_10715	ENOG4105C7I	Dehydrogenase
GWG05_10725	ENOG4105CD8	aminopeptidase N
GWG05_10730	ENOG4105CN1	protease
GWG05_10735	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
GWG05_10740	ENOG4108ZGC	gaf domain protein
GWG05_10755	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
GWG05_10770	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
GWG05_10780	ENOG4105C59	p-type ATPase
GWG05_10795	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
GWG05_10800	ENOG4105Q9Y	Universal stress protein
GWG05_10805	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
GWG05_10820	ENOG4108K3A	Glutathione S-transferase
GWG05_10825	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
GWG05_10830	ENOG4105C2J	ABC transporter
GWG05_10835	ENOG4105CNN	ABC, transporter
GWG05_10840	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
GWG05_10845	ENOG4108RVA	ribokinase
GWG05_10850	ENOG4105ETE	Transcriptional regulator (LacI family
GWG05_10865	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
GWG05_10880	ENOG4105BZU	Histidine kinase
GWG05_10885	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GWG05_10890	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
GWG05_10895	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GWG05_10900	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
GWG05_10905	ENOG41083UC	50s ribosomal protein L35
GWG05_10910	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GWG05_10915	ENOG4105C22	threonyL-tRNA synthetase
GWG05_10940	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GWG05_10945	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
GWG05_10950	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GWG05_10955	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GWG05_10960	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GWG05_10965	ENOG4105XPH	Ferredoxin
GWG05_10970	ENOG4105CA3	membrane-bound lytic murein transglycosylase
GWG05_10975	ENOG4105XZD	Fe-S protein
GWG05_10980	ENOG4105DM4	PTS System
GWG05_10985	ENOG4105DE4	1-phosphofructokinase
GWG05_10990	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
GWG05_10995	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
GWG05_11000	ENOG4105E0U	tyrosine-specific transport protein
GWG05_11015	ENOG4105C1J	atp-dependent rna helicase
GWG05_11025	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
GWG05_11030	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
GWG05_11035	ENOG4108DG9	Smr protein MutS2
GWG05_11070	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
GWG05_11130	ENOG4105K6T	rare lipoprotein A
GWG05_11135	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
GWG05_11140	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
GWG05_11145	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
GWG05_11150	ENOG4106371	Methyltransferase
GWG05_11155	ENOG4107S90	membrAne
GWG05_11165	ENOG4105CTQ	phosphohexokinase
GWG05_11170	ENOG4105CH2	amidohydrolase
GWG05_11180	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GWG05_11225	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
GWG05_11240	ENOG4105VP0	transcriptional regulator, lysR family
GWG05_11245	ENOG4105EJ9	Membrane
GWG05_11255	ENOG4106IUH	DTW domain containing protein
GWG05_11260	ENOG4105CPF	Cell wall formation (By similarity)
GWG05_11275	ENOG4105C1J	atp-dependent rna helicase
GWG05_11310	ENOG41061CK	Antibiotic biosynthesis monooxygenase
GWG05_11315	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
GWG05_11345	ENOG4105WQ3	Rna-binding protein
GWG05_11365	ENOG4105BZ1	(ABC) transporter
GWG05_11370	ENOG4105BZ1	(ABC) transporter
GWG05_11375	ENOG4105BZU	Histidine kinase
GWG05_11380	ENOG4105K63	Thioredoxin
GWG05_11385	ENOG4105C8P	)-transporter
GWG05_11395	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
GWG05_11415	ENOG4105CRQ	synthase (Component I)
GWG05_11425	ENOG4105C44	Serine transporter
GWG05_11430	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
GWG05_11435	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GWG05_11440	ENOG4105CYN	Serine protein kinase
GWG05_11445	ENOG4106AKX	UPF0229 protein
GWG05_11450	ENOG4105ED1	spovr family
GWG05_11455	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
GWG05_11460	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GWG05_11465	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
GWG05_11470	ENOG4105DQR	SNARE associated Golgi
GWG05_11480	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GWG05_11490	ENOG4105D0C	transport protein
GWG05_11495	ENOG4105E4C	Lytic transglycosylase catalytic
GWG05_11515	ENOG4108MRH	transcriptional regulatory protein
GWG05_11520	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
GWG05_11525	ENOG4105E2R	ROK family
GWG05_11530	ENOG4105C8Q	Methyl-accepting chemotaxis
GWG05_11540	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
GWG05_11545	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
GWG05_11550	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
GWG05_11570	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
GWG05_11575	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
GWG05_11580	ENOG4105DVI	reductase, NrfD
GWG05_11585	ENOG4105DA4	cytochrome c-type biogenesis protein
GWG05_11590	ENOG4107QX9	Thiol disulfide interChange protein
GWG05_11595	ENOG4108DMF	Cytochrome C biogenesis protein
GWG05_11600	ENOG41061WM	D-Alanyl-D-Alanine
GWG05_11610	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
GWG05_11615	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
GWG05_11640	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
GWG05_11645	ENOG4105DZ2	Transcriptional regulator
GWG05_11655	ENOG4105E0K	tonB-dependent siderophore receptor
GWG05_11660	ENOG4105BZU	Histidine kinase
GWG05_11665	ENOG4105BZU	Histidine kinase
GWG05_11670	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
GWG05_11675	ENOG4105CR8	Transcriptional regulator
GWG05_11680	ENOG4108RYK	Nad-dependent epimerase dehydratase
GWG05_11690	ENOG4105C28	cystathionine
GWG05_11695	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GWG05_11730	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GWG05_11740	ENOG4105F2I	Transposase
GWG05_11750	ENOG4105CNT	hydrolase family 2
GWG05_11755	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
GWG05_11760	ENOG4105EQR	Transposase IS116 IS110 IS902
GWG05_11775	ENOG41060NJ	transcriptional regulator
GWG05_11780	ENOG4105CMR	udp-glucose 4-epimerase
GWG05_11785	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
GWG05_11790	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
GWG05_11795	ENOG4105CA9	Pyruvate kinase
GWG05_11810	ENOG4105CGY	Dna recombination protein
GWG05_11850	ENOG410600T	transposase
GWG05_11855	ENOG4105D5G	Transposase
GWG05_11860	ENOG4105C4R	Atp-dependent dna helicase
GWG05_11870	ENOG4105F2I	Transposase
GWG05_11955	ENOG4105CAF	HipA N-terminal domain protein
GWG05_11965	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
GWG05_11980	ENOG4105CS2	ec 3.2.1.21
GWG05_11985	ENOG4105C5Y	PTS System
GWG05_11990	ENOG4106KNT	transcriptional regulator
GWG05_12000	ENOG4108RMJ	sensory transduction regulator
GWG05_12010	ENOG4107104	thymidine kinase
GWG05_12015	ENOG4107S6Z	Na H antiporter
GWG05_12025	ENOG4108WBT	adenosyltransferase
GWG05_12030	ENOG4105VRT	cytoplasmic protein
GWG05_12035	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
GWG05_12040	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
GWG05_12055	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
GWG05_12060	ENOG4105CFV	Tetratricopeptide repeat protein
GWG05_12070	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GWG05_12075	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
GWG05_12080	ENOG4105CAT	Cytidine monophosphate kinase
GWG05_12085	ENOG4108JEN	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
GWG05_12090	ENOG4105DUM	transcriptional regulator, lysR family
GWG05_12110	ENOG4108DBC	nitroreductase
GWG05_12115	ENOG4105CFC	Transporter
GWG05_12120	ENOG4105BZU	Histidine kinase
GWG05_12130	ENOG4105CBN	LysR family transcriptional regulator
GWG05_12135	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GWG05_12160	ENOG4107RGM	aldo keto reductase
GWG05_12165	ENOG4105VFU	Rna-binding protein
GWG05_12175	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
GWG05_12185	ENOG4105HA9	of methanol dehydrogenase type
GWG05_12205	ENOG4105E14	MotA TolQ exbB proton channel
GWG05_12210	ENOG4105ER2	Ompa motb domain protein
GWG05_12215	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GWG05_12220	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GWG05_12225	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GWG05_12230	ENOG4105GKE	subunit e
GWG05_12235	ENOG4107QIZ	NADH dehydrogenase
GWG05_12240	ENOG4108IEH	NADH dehydrogenase subunit g
GWG05_12245	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
GWG05_12250	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GWG05_12255	ENOG4107UFS	subunit j
GWG05_12260	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GWG05_12265	ENOG4105D65	subunit l
GWG05_12270	ENOG4105C8S	subunit m
GWG05_12275	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GWG05_12280	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
GWG05_12285	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
GWG05_12295	ENOG4105VPD	cellular component movement
GWG05_12300	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GWG05_12305	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GWG05_12310	ENOG4105N21	Membrane
GWG05_12315	ENOG4105CUT	histidyl-tRNA synthetase
GWG05_12320	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
GWG05_12325	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
GWG05_12335	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GWG05_12340	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GWG05_12355	ENOG4108ZIT	Ferredoxin, 2FE-2S
GWG05_12360	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
GWG05_12365	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
GWG05_12370	ENOG4108Z4V	iron-sulfur cluster assembly
GWG05_12375	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
GWG05_12380	ENOG4105C3J	Cysteine desulfurase
GWG05_12385	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
GWG05_12390	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
GWG05_12415	ENOG4105KHC	sulfurtransferase
GWG05_12420	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GWG05_12425	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GWG05_12430	ENOG4105VIE	preprotein translocase, subunit YajC
GWG05_12435	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
GWG05_12440	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
GWG05_12445	ENOG4105W87	Cbs domain
GWG05_12450	ENOG4105D3R	alkyl hydroperoxide reductase
GWG05_12490	ENOG4105C0D	helicase
GWG05_12555	ENOG410600T	transposase
GWG05_12570	ENOG4105F2I	Transposase
GWG05_12590	ENOG4105DZR	Type I site-specific deoxyribonuclease
GWG05_12595	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GWG05_12615	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GWG05_12620	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GWG05_12625	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
GWG05_12630	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GWG05_12635	ENOG4105D0A	hydroxylase
GWG05_12645	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
GWG05_12655	ENOG4105E5M	Multidrug resistance protein D
GWG05_12660	ENOG4105C3U	ABC transporter
GWG05_12665	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GWG05_12670	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GWG05_12680	ENOG4105CYM	Glutathione S-transferase
GWG05_12685	ENOG4108K3A	Glutathione S-transferase
GWG05_12695	ENOG4105ECY	inositol monophosphatase
GWG05_12700	ENOG4105EIY	sodium-type flagellar protein motY
GWG05_12710	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
GWG05_12715	ENOG4105D3Y	Na H antiporter
GWG05_12725	ENOG4105CC0	LysR family Transcriptional regulator
GWG05_12745	ENOG4105KA0	thioesterase Superfamily protein
GWG05_12755	ENOG4105CQB	FAD linked oxidase domain protein
GWG05_12770	ENOG4105EE5	Membrane protein terC
GWG05_12775	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GWG05_12785	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
GWG05_12790	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
GWG05_12800	ENOG4105CAQ	asparagine synthetase
GWG05_12815	ENOG4108RXX	maleylacetoacetate isomerase
GWG05_12825	ENOG4105F1J	Homogentisate 1,2-dioxygenase
GWG05_12830	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
GWG05_12840	ENOG4108W1A	pseudouridine synthase
GWG05_12845	ENOG4105BZU	Histidine kinase
GWG05_12855	ENOG4105CR4	methylisocitrate lyase
GWG05_12860	ENOG4105BZN	citrate synthase
GWG05_12865	ENOG4108I0Z	Aconitate hydratase
GWG05_12870	ENOG4105C7F	AcnD-accessory protein PrpF
GWG05_12880	ENOG4105CNM	Receptor
GWG05_12890	ENOG4108MN8	Membrane
GWG05_12895	ENOG4105EM2	membrane
GWG05_12900	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
GWG05_12905	ENOG4108S3P	Sporulation domain protein
GWG05_12910	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
GWG05_12915	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
GWG05_12920	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GWG05_12930	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GWG05_12935	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
GWG05_12945	ENOG4105D01	(LipO)protein
GWG05_12975	ENOG4105DKW	ABC transporter
GWG05_12980	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
GWG05_12985	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
GWG05_12995	ENOG4105C85	amino acid
GWG05_13030	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
GWG05_13040	ENOG4105N5T	Radical SAM Protein
GWG05_13045	ENOG4105CBC	glutamate synthase
GWG05_13050	ENOG4105BZ8	glutamate synthase
GWG05_13055	ENOG4105CDA	abc transporter atp-binding protein
GWG05_13065	ENOG410600T	transposase
GWG05_13075	ENOG4105EAB	amino acid AbC transporter
GWG05_13110	ENOG4105C1J	atp-dependent rna helicase
GWG05_13135	ENOG4107QS8	(LipO)protein
GWG05_13140	ENOG4106TD9	Diguanylate cyclase
GWG05_13145	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GWG05_13150	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GWG05_13155	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GWG05_13160	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GWG05_13170	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
GWG05_13175	ENOG4105E66	phosphoriboisomerase A
GWG05_13180	ENOG4108JQ1	Dehydrogenase
GWG05_13185	ENOG41080IJ	Diacylglycerol kinase
GWG05_13190	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GWG05_13195	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
GWG05_13200	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
GWG05_13215	ENOG4105CZX	twitching motility protein
GWG05_13225	ENOG4105CE1	Ferrous iron transport protein b
GWG05_13235	ENOG4108ZJT	translation initiation factor, Sui1
GWG05_13275	ENOG410620I	Diguanylate cyclase
GWG05_13280	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GWG05_13320	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GWG05_13330	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
GWG05_13335	ENOG4105Y3U	Transglycosylase-associated protein
GWG05_13340	ENOG4108WUH	Transcriptional regulator, TetR family
GWG05_13345	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
GWG05_13360	ENOG4105CBN	LysR family transcriptional regulator
GWG05_13385	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
GWG05_13390	ENOG4105WH1	Two component transcriptional regulator luxr family
GWG05_13395	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
GWG05_13400	ENOG4105W49	UPF0434 protein
GWG05_13405	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
GWG05_13410	ENOG4105BZ1	(ABC) transporter
GWG05_13415	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
GWG05_13430	ENOG4105D7A	ATP-binding protein
GWG05_13435	ENOG4105CGF	Aromatic amino acid aminotransferase
GWG05_13450	ENOG4105DVT	helicase
GWG05_13460	ENOG4105DGU	Histone deacetylase
GWG05_13465	ENOG4108ISG	Major Facilitator
GWG05_13470	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
GWG05_13475	ENOG4105G6Z	alkaline phosphatase
GWG05_13495	ENOG4105NXH	GreA GreB family elongation factor
GWG05_13500	ENOG4105BZU	Histidine kinase
GWG05_13505	ENOG4106TNF	Periplasmic binding protein
GWG05_13510	ENOG4105E5Q	amino acid AbC transporter
GWG05_13515	ENOG4105CDA	abc transporter atp-binding protein
GWG05_13525	ENOG4105D5Q	Arginine ornithine antiporter
GWG05_13530	ENOG4105C3R	Methionine synthase
GWG05_13540	ENOG4105C37	(CBS) domain
GWG05_13550	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GWG05_13555	ENOG4105E2Z	phosphate ABC transporter (Permease
GWG05_13560	ENOG4105C8U	phosphate abc transporter
GWG05_13565	ENOG4108Z6B	deaminase
GWG05_13575	ENOG4107QP3	malate synthase g
GWG05_13580	ENOG4108I9X	Isocitrate lyase
GWG05_13585	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
GWG05_13595	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
GWG05_13600	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
GWG05_13605	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
GWG05_13610	ENOG4107QNR	UPF0135 protein
GWG05_13620	ENOG4105BZU	Histidine kinase
GWG05_13635	ENOG4105RH4	Glycine cleavage system transcriptional repressor
GWG05_13640	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
GWG05_13645	ENOG4105C9X	ppx gppa phosphatase
GWG05_13650	ENOG4105CJW	magnesium transporter
GWG05_13665	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
GWG05_13670	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GWG05_13675	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GWG05_13680	ENOG4105CGA	flagellar basal-body rod protein FlgG
GWG05_13685	ENOG4108KPB	Flagellar basal-body rod protein FlgF
GWG05_13690	ENOG4105BZE	flagellar hook protein, FlgE
GWG05_13700	ENOG4108ZC9	flagellar basal-body rod protein flgc
GWG05_13705	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
GWG05_13710	ENOG4105BZU	Histidine kinase
GWG05_13720	ENOG4107ESN	Flagella basal body P-ring formation protein flgA
GWG05_13735	ENOG4108RE9	Phosphodiesterase
GWG05_13740	ENOG4107QSI	ABC, transporter
GWG05_13750	ENOG4105I08	Pseudouridine synthase
GWG05_13755	ENOG4105DHT	Metal Dependent Phosphohydrolase
GWG05_13765	ENOG4108594	Permease of the drug metabolite transporter
GWG05_13770	ENOG4105E43	Extracellular solute-binding protein, family 5
GWG05_13795	ENOG4105VEQ	Cold shock protein
GWG05_13800	ENOG4107QSN	dihydrolipoamide acetyltransferase
GWG05_13805	ENOG4105CPP	Dehydrogenase, E1 component
GWG05_13810	ENOG4107RUY	(E1 component), alpha subunit
GWG05_13825	ENOG4105KR1	Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity)
GWG05_13835	ENOG4108YXG	UPF0502 protein
GWG05_13850	ENOG4105E3R	(LipO)protein
GWG05_13855	ENOG4108Q9C	Periplasmic Protein
GWG05_13870	ENOG4105D75	Capsular exopolysaccharide family
GWG05_13875	ENOG4107ZF2	Phosphatase
GWG05_13880	ENOG4105DAY	polysaccharide export protein
GWG05_13910	ENOG4105K64	Glycosyl transferase, family 2
GWG05_13930	ENOG4105ESV	Glycosyl transferase, family 4
GWG05_13945	ENOG4105EXC	Acyl-transferase
GWG05_13955	ENOG4105EY8	ABC transporter
GWG05_13960	ENOG4105MFV	ABC-2 type transporter
GWG05_13965	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
GWG05_13975	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
GWG05_13980	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
GWG05_13985	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GWG05_14000	ENOG4106KNT	transcriptional regulator
GWG05_14005	ENOG4105CA9	Pyruvate kinase
GWG05_14015	ENOG4105BZS	acriflavin resistance protein
GWG05_14020	ENOG4107QPN	acyl-Coa dehydrogenase
GWG05_14030	ENOG4107SSZ	Phosphatase
GWG05_14040	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
GWG05_14045	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
GWG05_14050	ENOG4105BZS	acriflavin resistance protein
GWG05_14055	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
GWG05_14060	ENOG4108IG5	Transcriptional regulator
GWG05_14075	ENOG4105C29	acyl-CoA thioesterase
GWG05_14085	ENOG4105FE9	pseudouridine synthase
GWG05_14090	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
GWG05_14100	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
GWG05_14105	ENOG4105DB7	PHP domain protein
GWG05_14110	ENOG4105CRQ	synthase (Component I)
GWG05_14115	ENOG4108EFP	Anthranilate synthase component II
GWG05_14120	ENOG4108I0Q	anthranilate phosphoribosyltransferase
GWG05_14125	ENOG4105DK0	Indole-3-glycerol phosphate synthase
GWG05_14130	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GWG05_14135	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
GWG05_14195	ENOG4105JQN	Transcriptional regulator
GWG05_14205	ENOG4106FTQ	Taurine ABC transporter, periplasmic
GWG05_14210	ENOG4108ETV	ABC transporter
GWG05_14215	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
GWG05_14220	ENOG4105E2B	Taurine dioxygenase
GWG05_14225	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
GWG05_14230	ENOG4107RDB	Major Facilitator
GWG05_14235	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GWG05_14240	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
GWG05_14245	ENOG4105CCU	oxidase (Subunit III)
GWG05_14250	ENOG4105BZ9	Cytochrome C oxidase, subunit I
GWG05_14255	ENOG4105E2S	oxidase) subunit II
GWG05_14260	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
GWG05_14265	ENOG4105CC0	LysR family Transcriptional regulator
GWG05_14285	ENOG4105NTK	Transcriptional repressor Mpra
GWG05_14300	ENOG41090JD	Blue (Type 1) copper domain protein
GWG05_14315	ENOG4108VYJ	response regulator receiver protein
GWG05_14325	ENOG4105CGK	Exodeoxyribonuclease III
GWG05_14335	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
GWG05_14340	ENOG4108IJF	Heavy metal efflux pump, CzcA
GWG05_14355	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
GWG05_14360	ENOG4105BZU	Histidine kinase
GWG05_14375	ENOG4105KFG	YeeE YedE family protein
GWG05_14385	ENOG41080HT	Transcriptional regulator, arsr family
GWG05_14395	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
GWG05_14410	ENOG4105WBN	Transcriptional regulator (LacI family
GWG05_14425	ENOG4105D7K	pfkb domain protein
GWG05_14435	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GWG05_14440	ENOG4105CFG	Acts as a chaperone (By similarity)
GWG05_14445	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GWG05_14450	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GWG05_14455	ENOG4105BZU	Histidine kinase
GWG05_14460	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GWG05_14470	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
GWG05_14475	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GWG05_14480	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
GWG05_14485	ENOG4105Q26	Siderophore-interacting protein
GWG05_14500	ENOG4105W8I	Transcriptional regulator
GWG05_14505	ENOG4105BZC	d-serine deaminase
GWG05_14515	ENOG4108HMX	isocitrate dehydrogenase (NADP)
GWG05_14545	ENOG4108W0I	acetyltransferase
GWG05_14550	ENOG4108R99	pseudouridine synthase
GWG05_14560	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GWG05_14565	ENOG41075W9	High frequency lysogenization protein HflD homolog
GWG05_14570	ENOG4107QTF	adenylosuccinate lyase
GWG05_14575	ENOG4105EZE	Cupin 4 family protein
GWG05_14580	ENOG4105CA9	Pyruvate kinase
GWG05_14585	ENOG4105EGS	Mechanosensitive ion channel
GWG05_14605	ENOG4105C2W	permease
GWG05_14615	ENOG4107R1I	NAD-dependent malic enzyme
GWG05_14620	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
GWG05_14625	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
GWG05_14630	ENOG4105DR8	Membrane
GWG05_14635	ENOG4108ESY	Metal dependent phosphohydrolase
GWG05_14645	ENOG4107SDU	Methyl-accepting chemotaxis
GWG05_14665	ENOG4105E18	UPF0276 protein
GWG05_14675	ENOG4105C94	Transporter
GWG05_14700	ENOG4105I4A	GCN5-related N-acetyltransferase
GWG05_14715	ENOG4105D98	threonine synthase
GWG05_14720	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
GWG05_14735	ENOG4106FVC	RNA methyltransferase
GWG05_14740	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
GWG05_14755	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
GWG05_14765	ENOG41065U4	response regulator
GWG05_14780	ENOG4108JJ9	ABC, transporter
GWG05_14785	ENOG4108JJ8	(ABC) transporter
GWG05_14805	ENOG4108R96	Methyltransferase, YaeB family
GWG05_14820	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GWG05_14825	ENOG4105C6T	cysteine synthase
GWG05_14830	ENOG4105KZ7	phosphocarrier protein hpr
GWG05_14835	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
GWG05_14840	ENOG4105C5Y	PTS System
GWG05_14845	ENOG4105CPW	cytochrome b561
GWG05_14850	ENOG4105EYH	Exonuclease
GWG05_14855	ENOG4107RH8	nuclease SbcCD subunit D
GWG05_14860	ENOG4105WCN	acetyltransferase
GWG05_14865	ENOG4105DH7	May be involved in recombination (By similarity)
GWG05_14875	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
GWG05_14880	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
GWG05_14885	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GWG05_14915	ENOG4105CJP	fad dependent oxidoreductase
GWG05_14920	ENOG4107VRI	Transcriptional regulator
GWG05_14925	ENOG4105C26	Dehydrogenase
GWG05_14930	ENOG4108JPW	Aminotransferase
GWG05_14935	ENOG4105CUB	amino acid
GWG05_14940	ENOG4105CUB	amino acid
GWG05_14955	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GWG05_14960	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
GWG05_14965	ENOG4105BZU	Histidine kinase
GWG05_14970	ENOG4105XIQ	Protein of unknown function (DUF2517)
GWG05_14990	ENOG4105BZU	Histidine kinase
GWG05_15000	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
GWG05_15015	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
GWG05_15020	ENOG4107TT5	NLP P60 protein
GWG05_15025	ENOG4107YAK	holo-(acyl carrier protein) synthase 2
GWG05_15030	ENOG4107QR8	Thioredoxin
GWG05_15040	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
GWG05_15045	ENOG4105CIY	formyltetrahydrofolate deformylase
GWG05_15070	ENOG4105E4C	Lytic transglycosylase catalytic
GWG05_15080	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GWG05_15085	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
GWG05_15090	ENOG4105EP9	oxidoreductase
GWG05_15120	ENOG4105CCT	upf0313 protein
GWG05_15125	ENOG4105BZS	acriflavin resistance protein
GWG05_15135	ENOG4105BZU	Histidine kinase
GWG05_15140	ENOG4105D78	K07001 NTE family protein
GWG05_15145	ENOG4105C8J	)-transporter
GWG05_15160	ENOG4105UYK	outer membrane protein a
GWG05_15170	ENOG4105UYK	outer membrane protein a
GWG05_15175	ENOG4107R1I	NAD-dependent malic enzyme
GWG05_15180	ENOG41075H3	AraC family transcriptional regulator
GWG05_15190	ENOG4105RKX	Protein of unknown function (DUF2498)
GWG05_15200	ENOG4105C2W	permease
GWG05_15205	ENOG4108KMH	lipoate-protein ligase a
GWG05_15210	ENOG4105BZG	amino acid carrier protein
GWG05_15230	ENOG4105PTV	Nudix Hydrolase
GWG05_15240	ENOG4105CDA	abc transporter atp-binding protein
GWG05_15245	ENOG4105DRP	amino acid AbC transporter
GWG05_15250	ENOG4105EZ7	amino acid ABC transporter
GWG05_15270	ENOG4105CJ1	ABC, transporter
GWG05_15275	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GWG05_15295	ENOG4106N3A	copper homeostasis protein cutc
GWG05_15300	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
GWG05_15310	ENOG4105ERG	peptidase m48, ste24p
GWG05_15315	ENOG4105DJH	phosphate
GWG05_15320	ENOG4105BZU	Histidine kinase
GWG05_15325	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GWG05_15330	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
GWG05_15335	ENOG4105BZU	Histidine kinase
GWG05_15340	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
GWG05_15345	ENOG4105C26	Dehydrogenase
GWG05_15355	ENOG4108IPJ	Membrane
GWG05_15365	ENOG4105CPC	Aldo Keto reductase
GWG05_15375	ENOG4106YYS	transcriptional regulatory protein
GWG05_15380	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
GWG05_15390	ENOG4105J12	Multidrug resistance protein mdtN
GWG05_15415	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
GWG05_15420	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
GWG05_15430	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GWG05_15435	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
GWG05_15440	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
GWG05_15445	ENOG4105EXN	Sulfate transport protein CysZ
GWG05_15450	ENOG4105EN6	Membrane
GWG05_15460	ENOG4105EAQ	(twin-arginine translocation) pathway signal
GWG05_15465	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
GWG05_15495	ENOG4107T9C	Alpha amylase catalytic region
GWG05_15540	ENOG4105BZU	Histidine kinase
GWG05_15545	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GWG05_15550	ENOG4105C9K	Endothelin-converting enzyme 1
GWG05_15560	ENOG4105C5H	ABC transporter
GWG05_15570	ENOG4105DVH	amino acid
GWG05_15575	ENOG4105C44	Serine transporter
GWG05_15580	ENOG4105EQ2	LysR family Transcriptional regulator
GWG05_15590	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
GWG05_15595	ENOG4105C0B	DNA polymerase III (alpha subunit)
GWG05_15600	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GWG05_15605	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GWG05_15610	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GWG05_15615	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GWG05_15620	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GWG05_15625	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
GWG05_15635	ENOG4105DZP	Membrane-associated zinc metalloprotease
GWG05_15640	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
GWG05_15645	ENOG4105KNE	Phosphatidate cytidylyltransferase
GWG05_15655	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GWG05_15660	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GWG05_15665	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GWG05_15670	ENOG4105CE9	30S ribosomal protein S2
GWG05_15675	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GWG05_15680	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
GWG05_15685	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
GWG05_15690	ENOG4108T8E	UPF0325 protein
GWG05_15695	ENOG4105CI1	PTS System
GWG05_15700	ENOG4107W52	maltose operon periplasmic protein
GWG05_15715	ENOG4105QDK	Flavodoxin
GWG05_15720	ENOG4105DR9	pseudouridine synthase
GWG05_15725	ENOG4105WP7	tRNA pseudouridine synthase C
GWG05_15750	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
GWG05_15755	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
GWG05_15760	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
GWG05_15770	ENOG4105BZU	Histidine kinase
GWG05_15775	ENOG4105EWT	decarboxylase family
GWG05_15780	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
GWG05_15785	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GWG05_15795	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
GWG05_15810	ENOG4105ETT	transcriptional Regulator, LysR family
GWG05_15815	ENOG4105C8Q	Methyl-accepting chemotaxis
GWG05_15820	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GWG05_15835	ENOG4105CJ2	(LipO)protein
GWG05_15840	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
GWG05_15845	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GWG05_15850	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GWG05_15855	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GWG05_15860	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GWG05_15865	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GWG05_15870	ENOG4105M85	Bola protein
GWG05_15875	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
GWG05_15885	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GWG05_15895	ENOG4105EYM	Major Facilitator superfamily
GWG05_15900	ENOG4105DRB	nucleoside-specific channel-forming protein
GWG05_15905	ENOG4108VPT	UPF0234 protein
GWG05_15910	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
GWG05_15915	ENOG4107S0N	DJ-1 family
GWG05_15920	ENOG4105CHH	sulfate transporter
GWG05_15925	ENOG4105BZU	Histidine kinase
GWG05_15930	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GWG05_15935	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
GWG05_15940	ENOG4105BZS	acriflavin resistance protein
GWG05_15955	ENOG4105CMR	udp-glucose 4-epimerase
GWG05_15965	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
GWG05_15970	ENOG4108RMU	ferritin dps family protein
GWG05_15995	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
GWG05_16010	ENOG4105EMU	Dehydrogenase
GWG05_16020	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GWG05_16025	ENOG4108XDN	Transcriptional regulator
GWG05_16030	ENOG4107SEY	Conserved Protein
GWG05_16085	ENOG4105D8V	Glucose sorbosone dehydrogenase
GWG05_16095	ENOG4105MVE	transcriptional regulator
GWG05_16105	ENOG4105G63	Type III effector Hrp-dependent
GWG05_16110	ENOG4105FB2	class II Aldolase
GWG05_16115	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
GWG05_16120	ENOG4105EXW	epimerase dehydratase
GWG05_16125	ENOG4105C6Z	Gluconate
GWG05_16135	ENOG4105C8Q	Methyl-accepting chemotaxis
GWG05_16145	ENOG4105E1F	short-chain dehydrogenase reductase
GWG05_16170	ENOG4105CTD	carboxy-peptidase
GWG05_16190	ENOG4105XDF	Protein of unknown function (DUF1272)
GWG05_16200	ENOG4105CFP	Peptidase U32
GWG05_16205	ENOG4105N14	lysine exporter protein LysE YggA
GWG05_16215	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GWG05_16240	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
GWG05_16250	ENOG4105DB1	molybdopterin oxidoreductase
GWG05_16255	ENOG4106WHD	Tetrathionate reductase
GWG05_16260	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
GWG05_16265	ENOG4105BZU	Histidine kinase
GWG05_16270	ENOG4108ZXC	Two component transcriptional regulator, luxr family
GWG05_16275	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
GWG05_16280	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GWG05_16285	ENOG4105CW7	secretion protein, HlyD family
GWG05_16305	ENOG4105C26	Dehydrogenase
GWG05_16310	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GWG05_16315	ENOG4105CDU	Replicative dna helicase
GWG05_16325	ENOG4105CGH	5'-nucleotidase
GWG05_16345	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GWG05_16350	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GWG05_16360	ENOG4105VRX	Protein slyX homolog
GWG05_16365	ENOG4108YZY	peptidylprolyl cis-trans isomerase
GWG05_16370	ENOG4105VKU	nucleicacid-binding protein
GWG05_16385	ENOG4105DNZ	Alpha Beta Hydrolase
GWG05_16395	ENOG4105YP7	UPF0270 protein
GWG05_16400	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
GWG05_16415	ENOG4108UKZ	OsmC family
GWG05_16420	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
GWG05_16425	ENOG4105DHI	Methyltransferase
GWG05_16435	ENOG4105BZU	Histidine kinase
GWG05_16440	ENOG4105D8G	Major Facilitator superfamily
GWG05_16465	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
GWG05_16470	ENOG41090JE	Utilization Protein
GWG05_16480	ENOG4105EHG	Permease protein
GWG05_16495	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
GWG05_16505	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
GWG05_16515	ENOG4105CKK	Glycosyl transferase, family 2
GWG05_16520	ENOG4105E4C	Lytic transglycosylase catalytic
GWG05_16525	ENOG4105C5H	ABC transporter
GWG05_16535	ENOG4105C7N	Xanthine uracil vitamin C permease
GWG05_16540	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
GWG05_16545	ENOG4108S0S	Nucleotidyl transferase
GWG05_16550	ENOG4105EHM	Aminoglycoside phosphotransferase
GWG05_16555	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
GWG05_16565	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
GWG05_16570	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GWG05_16580	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
GWG05_16590	ENOG4105DEN	Luciferase family
GWG05_16595	ENOG4108ESY	Metal dependent phosphohydrolase
GWG05_16600	ENOG4105DWD	nucleoside recognition domain protein
GWG05_16605	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GWG05_16610	ENOG4105K46	50S ribosomal protein l27
GWG05_16615	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GWG05_16620	ENOG4105EAH	synthase
GWG05_16630	ENOG4105EPW	hflc protein
GWG05_16635	ENOG4107QJR	hflk protein
GWG05_16640	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GWG05_16645	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
GWG05_16650	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GWG05_16655	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
GWG05_16660	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GWG05_16665	ENOG4105K8N	protein family UPF0079, ATPase
GWG05_16670	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GWG05_16690	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
GWG05_16695	ENOG4108UMI	ABC transporter, permease
GWG05_16700	ENOG4105D01	(LipO)protein
GWG05_16705	ENOG4105MDZ	Transcriptional activator rfaH
GWG05_16710	ENOG4107SDU	Methyl-accepting chemotaxis
GWG05_16715	ENOG4105BZU	Histidine kinase
GWG05_16735	ENOG4105BZU	Histidine kinase
GWG05_16755	ENOG4108Q67	UPF0319 protein
GWG05_16760	ENOG4105EXG	Transcriptional regulator
GWG05_16770	ENOG4107QWK	SAICAR synthetase
GWG05_16775	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GWG05_16780	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GWG05_16785	ENOG4105RH4	Glycine cleavage system transcriptional repressor
GWG05_16790	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GWG05_16795	ENOG4105XWI	UPF0304 protein
GWG05_16805	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GWG05_16810	ENOG4105C6K	Malic enzyme
GWG05_16815	ENOG4108ZP8	Acetolactate synthase small subunit
GWG05_16825	ENOG4105C7K	acetolactate synthase
GWG05_16840	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
GWG05_16850	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GWG05_16860	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GWG05_16865	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GWG05_16880	ENOG4105DP9	ABC transporter
GWG05_16885	ENOG4106SMU	thiamine transporter membrane protein
GWG05_16890	ENOG4107T0D	ABC, transporter
GWG05_16895	ENOG4108IAB	Phoh family
GWG05_16905	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GWG05_16935	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
GWG05_16945	ENOG4105CMQ	Chloride channel
GWG05_16950	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
GWG05_16965	ENOG41076MN	Phosphoesterase, PA-phosphatase related
GWG05_16975	ENOG4105EGI	Transcriptional regulator
GWG05_16980	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
GWG05_16985	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
GWG05_16990	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
GWG05_16995	ENOG4105BZ4	penicillin-binding protein
GWG05_17000	ENOG4105CQ7	ATP-dependent helicase
GWG05_17010	ENOG4105PW4	Sugar fermentation stimulation protein homolog
GWG05_17020	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
GWG05_17025	ENOG4105DJ0	Poly(A) Polymerase
GWG05_17030	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GWG05_17035	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
GWG05_17040	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
GWG05_17050	ENOG4105E3A	(ABC) transporter
GWG05_17055	ENOG4105DA5	(ABC) transporter
GWG05_17060	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
GWG05_17065	ENOG410630P	Transcriptional regulator
GWG05_17070	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
GWG05_17075	ENOG4105DFU	Cell wall formation (By similarity)
GWG05_17080	ENOG4105F0N	pyrophosphate phospho-hydrolase
GWG05_17095	ENOG4108UUE	Transcriptional regulator
GWG05_17110	ENOG4105C19	ABC transporter
GWG05_17160	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
GWG05_17170	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
GWG05_17175	ENOG4105C11	sulfate adenylyltransferase), subunit 2
GWG05_17180	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GWG05_17185	ENOG4107QX8	SPFH domain, Band 7 family protein
GWG05_17190	ENOG4105G5H	Membrane
GWG05_17200	ENOG4105D9R	oxidoreductase
GWG05_17210	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GWG05_17215	ENOG4105CSA	Coproporphyrinogen iii oxidase
GWG05_17235	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GWG05_17240	ENOG4105C12	Phosphoribosylglycinamide synthetase
GWG05_17285	ENOG4105F2I	Transposase
GWG05_17315	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GWG05_17320	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GWG05_17325	ENOG4105KTH	gatB Yqey
GWG05_17330	ENOG4105VCC	30S ribosomal protein S21
GWG05_17335	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GWG05_17345	ENOG4108K5P	(LipO)protein
GWG05_17350	ENOG4108UM1	dedA family
GWG05_17355	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
GWG05_17360	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
GWG05_17365	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
GWG05_17370	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
GWG05_17375	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
GWG05_17380	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
GWG05_17385	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
GWG05_17390	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GWG05_17395	ENOG4105DXN	mazG family
GWG05_17400	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GWG05_17405	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GWG05_17410	ENOG4105BZU	Histidine kinase
GWG05_17415	ENOG4108W15	Protein of unknown function (DUF1456)
GWG05_17420	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
GWG05_17425	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
GWG05_17430	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
GWG05_17440	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
GWG05_17445	ENOG4105C3F	Signal peptidase i
GWG05_17450	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
GWG05_17465	ENOG41069PW	sigma-e factor negative regulatory protein
GWG05_17470	ENOG4105EMN	RNA polymerase sigma factor
GWG05_17475	ENOG4108IYU	L-aspartate oxidase
GWG05_17485	ENOG4105Y75	tpr repeat protein
GWG05_17495	ENOG4105DUM	transcriptional regulator, lysR family
GWG05_17510	ENOG4105VF7	tolerance protein
GWG05_17515	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
GWG05_17525	ENOG4105CJP	fad dependent oxidoreductase
GWG05_17530	ENOG4105D2N	Aldolase
GWG05_17535	ENOG4105BZA	Phosphoglycerate kinase
GWG05_17540	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GWG05_17545	ENOG4105DKQ	ROK family
GWG05_17550	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
GWG05_17555	ENOG4105E09	nadh pyrophosphatase
GWG05_17560	ENOG4106MWK	domain protein
GWG05_17565	ENOG4105EYW	Ion transport protein
GWG05_17570	ENOG4105C8Q	Methyl-accepting chemotaxis
GWG05_17580	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
GWG05_17585	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
GWG05_17600	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
GWG05_17605	ENOG4105E5Q	amino acid AbC transporter
GWG05_17610	ENOG4105E5Q	amino acid AbC transporter
GWG05_17615	ENOG4105CDA	abc transporter atp-binding protein
GWG05_17620	ENOG4105CT1	(ABC) transporter
GWG05_17625	ENOG4107PU6	Membrane
GWG05_17630	ENOG4108UW5	maltose o-acetyltransferase
GWG05_17660	ENOG41090U3	tautomerase
GWG05_17670	ENOG4107NQ8	LysR family Transcriptional regulator
GWG05_17675	ENOG4105CH7	arginosuccinase
GWG05_17680	ENOG4105CDH	Citrulline--aspartate ligase
GWG05_17690	ENOG4105CAS	nag kinase
GWG05_17695	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
GWG05_17705	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
GWG05_17710	ENOG4105BZU	Histidine kinase
GWG05_17715	ENOG4108Z66	YbaK ebsC protein
GWG05_17755	ENOG4105CMU	LysR family (Transcriptional regulator
GWG05_17765	ENOG41067MG	lrgb family
GWG05_17770	ENOG4105CFH	Aspartokinase
GWG05_17775	ENOG4105C28	cystathionine
GWG05_17780	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
GWG05_17790	ENOG4108Z7R	Chaperone CsaA
GWG05_17795	ENOG4105C44	Serine transporter
GWG05_17800	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
GWG05_17805	ENOG4107RK2	ADP-ribose diphosphatase NudE
GWG05_17810	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
GWG05_17820	ENOG4105JQN	Transcriptional regulator
GWG05_17825	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GWG05_17830	ENOG4108UDW	Transcriptional regulator, luxr family
GWG05_17875	ENOG4108VAU	general secretion pathway protein G
GWG05_17880	ENOG4105D7Q	type ii secretion system
GWG05_17885	ENOG4107QHF	type ii secretion system protein e
GWG05_17890	ENOG4105GVR	general secretion pathway protein D
GWG05_17900	ENOG4105VEJ	Heat shock protein
GWG05_17905	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
GWG05_17910	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
GWG05_17930	ENOG4108XTF	Outer Membrane Lipoprotein
GWG05_17935	ENOG4105I7R	Adenylate cyclase
GWG05_17940	ENOG4107IX6	phosphate transport regulator
GWG05_17945	ENOG4105CJ3	phosphate transporter
GWG05_17950	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GWG05_17965	ENOG4105CEN	a g-specific adenine glycosylase
GWG05_17970	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
GWG05_17995	ENOG4108Q2G	(LipO)protein
GWG05_18000	ENOG4105DY2	Paraquat-inducible protein b
GWG05_18005	ENOG4105F1S	paraquat-inducible protein a
GWG05_18010	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
GWG05_18015	ENOG4107VXZ	Hydrolase
GWG05_18025	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GWG05_18030	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
GWG05_18035	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GWG05_18040	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
GWG05_18080	ENOG4105DFD	Na H antiporter
GWG05_18095	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GWG05_18100	ENOG4105D81	ABC transporter, permease
GWG05_18105	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
GWG05_18110	ENOG4105C26	Dehydrogenase
GWG05_18115	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GWG05_18145	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
GWG05_18155	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
GWG05_18160	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
GWG05_18175	ENOG4108UQY	Iron-storage protein
GWG05_18180	ENOG4108Z5K	methylglyoxal synthase
GWG05_18195	ENOG4105HDK	L-asparaginase
GWG05_18210	ENOG4105D4X	repressor
GWG05_18215	ENOG4105C5Y	PTS System
GWG05_18220	ENOG4105CG3	alpha amylase, catalytic region
GWG05_18225	ENOG4108UW5	maltose o-acetyltransferase
GWG05_18260	ENOG4105R2J	Conserved Protein
GWG05_18270	ENOG4105DR5	peptidase
GWG05_18290	ENOG4105NXV	High-affinity zinc uptake system protein
GWG05_18295	ENOG4105FDK	ABC transporter
GWG05_18300	ENOG4105FAV	ABC, transporter
GWG05_18305	ENOG4105ETT	transcriptional Regulator, LysR family
GWG05_18315	ENOG4108RG0	uracil-dna glycosylase
GWG05_18320	ENOG4105FR1	rard protein
GWG05_18325	ENOG41082IR	Excinuclease ABC C subunit domain protein
GWG05_18340	ENOG41087YS	Phage shock protein A
GWG05_18345	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
GWG05_18365	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GWG05_18375	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GWG05_18445	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GWG05_18450	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GWG05_18455	ENOG4105DSW	Fusaric acid resistance protein
GWG05_18460	ENOG4105Y49	secretion protein, HlyD family
GWG05_18480	ENOG4105IPS	esterase
GWG05_18485	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
GWG05_18490	ENOG4108SX3	cytoplasmic protein
GWG05_18495	ENOG41087AY	ADP-Ribose pyrophosphatase
GWG05_18500	ENOG4105DFG	type I secretion outer membrane protein
GWG05_18505	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
GWG05_18510	ENOG4105D1S	lipid A biosynthesis
GWG05_18515	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
GWG05_18520	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
GWG05_18525	ENOG4105VJY	transcriptional regulator
GWG05_18530	ENOG4105NNS	Autoinducer synthesis protein
GWG05_18535	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
GWG05_18540	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
GWG05_18545	ENOG4105CTS	PTS system mannitol-specific
GWG05_18550	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
GWG05_18555	ENOG4105E61	Mannitol repressor protein
GWG05_18560	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
GWG05_18580	ENOG4108UPT	UPF0178 protein
GWG05_18600	ENOG410600T	transposase
GWG05_18620	ENOG4105C1J	atp-dependent rna helicase
GWG05_18640	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
GWG05_18645	ENOG4105E4F	Isochorismate synthase
GWG05_18650	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
GWG05_18655	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
GWG05_18660	ENOG4108IPT	Naphthoate synthase
GWG05_18665	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
GWG05_18670	ENOG4105CEY	Amp-dependent synthetase and ligase
GWG05_18675	ENOG4107MM9	BNR Asp-box repeat-containing protein
GWG05_18680	ENOG4108UB4	uncharacterized protein ygjQ
GWG05_18685	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GWG05_18695	ENOG4107IFA	Lipase (EC 3.1.1.3)
GWG05_18725	ENOG4108IQK	o-acetylhomoserine
GWG05_18735	ENOG4108I6A	alcohol dehydrogenase
GWG05_18750	ENOG4105EMU	Dehydrogenase
GWG05_18770	ENOG4105KT7	mgtC SapB transporter
GWG05_18785	ENOG4105E0M	Sulfatase
GWG05_18790	ENOG4108YXU	transcriptional regulator AsnC family
GWG05_18800	ENOG4105CVG	Homoserine O-transsuccinylase
GWG05_18810	ENOG4108I62	cina-like protein
GWG05_18815	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
GWG05_18830	ENOG410667J	hydrolase
GWG05_18835	ENOG4108Z86	Glutamine amidotransferase
GWG05_18845	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
GWG05_18850	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GWG05_18860	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
GWG05_18865	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GWG05_18875	ENOG4105XQ6	frataxin-like protein
GWG05_18880	ENOG4106CJB	Phospholipase Carboxylesterase
GWG05_18885	ENOG4107T0K	Adenylate cyclase
GWG05_18890	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
GWG05_18895	ENOG41076E6	Uroporphyrinogen-III Synthase
GWG05_18900	ENOG4105ECF	c-methyltransferase
GWG05_18905	ENOG410601J	HemY protein
GWG05_18910	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
GWG05_18915	ENOG4105N42	UPF0307 protein
GWG05_18925	ENOG41090HJ	UPF0265 protein
GWG05_18960	ENOG4108JCI	Transcriptional regulator
GWG05_18965	ENOG4105DKK	Benzoate
GWG05_18975	ENOG4105SYT	Methylenetetrahydrofolate reductase
GWG05_18995	ENOG4105EIF	outer membrane protein W
GWG05_19000	ENOG410600T	transposase
GWG05_19005	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
GWG05_19010	ENOG41086KC	Transcriptional regulator
GWG05_19015	ENOG4108UUM	single-stranded DNA-binding protein
GWG05_19035	ENOG4105VEQ	Cold shock protein
GWG05_19040	ENOG4105E0F	Histidine kinase
GWG05_19055	ENOG4108NVR	Methyl-accepting chemotaxis
GWG05_19065	ENOG4105BZU	Histidine kinase
GWG05_19070	ENOG4108YZA	Nitrogen regulatory protein pii
GWG05_19085	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
GWG05_19100	ENOG4107QYX	exodeoxyribonuclease v alpha
GWG05_19105	ENOG4107QKA	exodeoxyribonuclease V beta
GWG05_19110	ENOG4105DSY	exodeoxyribonuclease V, gamma
GWG05_19115	ENOG4108VBZ	doxx family
GWG05_19120	ENOG4105C2I	pirin domain protein
GWG05_19130	ENOG4105CWB	LysR family transcriptional Regulator
GWG05_19155	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
GWG05_19165	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GWG05_19195	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
GWG05_19200	ENOG4105CH6	catalase
GWG05_19225	ENOG4105IPI	Membrane
GWG05_19235	ENOG4105DWY	Agmatine deiminase
GWG05_19250	ENOG4105DWY	Agmatine deiminase
GWG05_19255	ENOG4105ETT	transcriptional Regulator, LysR family
GWG05_19270	ENOG4108UTZ	Dihydroxyacetone kinase
GWG05_19275	ENOG4105CMT	Dihydroxyacetone kinase
GWG05_19280	ENOG4105C7N	Xanthine uracil vitamin C permease
GWG05_19285	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
GWG05_19320	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
GWG05_19325	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GWG05_19330	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GWG05_19335	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GWG05_19340	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
GWG05_19345	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
GWG05_19355	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
GWG05_19360	ENOG4105KME	endoribonuclease L-psp
GWG05_19365	ENOG4105WWK	YheO domain protein
GWG05_19370	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GWG05_19375	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GWG05_19380	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GWG05_19385	ENOG4108VZM	50s ribosomal protein L10
GWG05_19390	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
GWG05_19395	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
GWG05_19400	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
GWG05_19405	ENOG4105PM1	preprotein translocase subunit SecE
GWG05_19415	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GWG05_19430	ENOG4105CS9	pantothenic acid kinase
GWG05_19435	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
GWG05_19440	ENOG4105D4A	Cell wall formation (By similarity)
GWG05_19445	ENOG4107ZYR	domain protein
GWG05_19455	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GWG05_19460	ENOG4105CUW	cytochrome C-TYPE protein
GWG05_19465	ENOG4107QY8	reductase
GWG05_19480	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GWG05_19495	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
GWG05_19500	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
GWG05_19510	ENOG4108UQ5	membrane protein YcdZ
GWG05_19515	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GWG05_19525	ENOG4107WP9	Histidine kinase
GWG05_19540	ENOG410642E	Short chain dehydrogenase
GWG05_19545	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GWG05_19555	ENOG4108VVK	transcriptional Regulator, AsnC
GWG05_19560	ENOG4105CU9	asparagine synthetase A
GWG05_19575	ENOG4105ETT	transcriptional Regulator, LysR family
GWG05_19580	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GWG05_19585	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
GWG05_19590	ENOG4105C34	Pseudouridine synthase
GWG05_19595	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GWG05_19600	ENOG4105CEM	UPF0597 protein
GWG05_19610	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GWG05_19615	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GWG05_19620	ENOG4108I6A	alcohol dehydrogenase
GWG05_19625	ENOG4105CF7	AraC family transcriptional regulator
GWG05_19630	ENOG4105QNF	Outer membrane lipoprotein
GWG05_19640	ENOG4105C8Q	Methyl-accepting chemotaxis
GWG05_19650	ENOG4105DUM	transcriptional regulator, lysR family
GWG05_19670	ENOG4105CXT	aspartate transcarbamylase
GWG05_19675	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
GWG05_19680	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
GWG05_19685	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
GWG05_19690	ENOG4105DBV	ornithine carbamoyltransferase
GWG05_19695	ENOG4105C5B	carbamate kinase
GWG05_19705	ENOG4105C8Q	Methyl-accepting chemotaxis
GWG05_19710	ENOG4107SDZ	Galactoside transport system permease protein mglC
GWG05_19725	ENOG4105CNT	hydrolase family 2
GWG05_19730	ENOG41060NJ	transcriptional regulator
GWG05_19735	ENOG4105CMR	udp-glucose 4-epimerase
GWG05_19740	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
GWG05_19745	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
GWG05_19750	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
GWG05_19755	ENOG4105CPC	Aldo Keto reductase
GWG05_19760	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GWG05_19765	ENOG4108NIX	Factor ChrR
GWG05_19770	ENOG4105K6V	RNA polymerase
GWG05_19780	ENOG4105C75	arginyL-tRNA synthetase
GWG05_19790	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
GWG05_19795	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
GWG05_19800	ENOG4105C57	major facilitator superfamily
GWG05_19805	ENOG41064T2	transcriptional regulator, lysR family
GWG05_19815	ENOG4105D0S	secretion protein (HlyD
GWG05_19820	ENOG4105CJ1	ABC, transporter
GWG05_19825	ENOG4107QWP	ABC-2 type transporter
GWG05_19830	ENOG4107QWP	ABC-2 type transporter
GWG05_19835	ENOG4107QZF	nitrite reductase NADPH large subunit
GWG05_19840	ENOG4105WZK	nitrite reductase NADPH small subunit
GWG05_19845	ENOG4107V9H	nitrite transporter
GWG05_19850	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GWG05_19855	ENOG4105CJW	magnesium transporter
GWG05_19860	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
GWG05_19865	ENOG4105EX9	Membrane
GWG05_19875	ENOG4105CNG	UPF0061 protein
GWG05_19880	ENOG4105N7H	Cytochrome
GWG05_19885	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GWG05_19890	ENOG4108VUY	thioesterase Superfamily protein
GWG05_19905	ENOG4108RPX	mosc domain containing protein
GWG05_19910	ENOG4105D38	putrescine abc transporter
GWG05_19915	ENOG4105F38	ABC transporter, permease
GWG05_19920	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GWG05_19925	ENOG4108HM4	ABC transporter
GWG05_19935	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GWG05_19940	ENOG4105CFQ	glutamine synthetase
GWG05_19945	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GWG05_19960	ENOG4108RH0	Crea protein
GWG05_19965	ENOG4105C5I	Dehydrogenase
GWG05_19970	ENOG4105R8A	Heat shock protein
GWG05_19985	ENOG4107R28	alpha amylase, catalytic region
GWG05_20000	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
GWG05_20005	ENOG4107EXC	regulatoR
GWG05_20015	ENOG4105JJR	Histidine kinase
GWG05_20025	ENOG4105C6K	Malic enzyme
GWG05_20030	ENOG4105CGD	Nad-dependent epimerase dehydratase
GWG05_20035	ENOG4105VFB	Binds the 23S rRNA (By similarity)
GWG05_20040	ENOG4105C25	Primosomal protein n'
GWG05_20045	ENOG4105F2I	Transposase
GWG05_20050	ENOG4105UYK	outer membrane protein a
GWG05_20055	ENOG4105C7B	Threonine dehydratase
GWG05_20060	ENOG4105C01	Dihydroxy-acid dehydratase
GWG05_20065	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GWG05_20070	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
GWG05_20085	ENOG4105C0P	Mg chelatase subunit ChlI
GWG05_20090	ENOG4106HNH	Acyl-transferase
GWG05_20095	ENOG4106HNH	Acyl-transferase
GWG05_20100	ENOG4105EWC	Purine nucleoside phosphorylase
GWG05_20110	ENOG4108RWI	nicotinamidase
GWG05_20115	ENOG4107RH7	Nicotinate phosphoribosyltransferase
GWG05_20120	ENOG4108Z33	Thiol disulfide Interchange Protein
GWG05_20125	ENOG4105E27	serine threonine protein kinase
GWG05_20135	ENOG4105PC1	Conserved Protein
GWG05_20155	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GWG05_20160	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
GWG05_20165	ENOG4105DSJ	YicC domain protein
GWG05_20175	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
GWG05_20180	ENOG4105XA0	heptosyltransferase ii
GWG05_20185	ENOG4106WTF	Glycosyl transferase, family 2
GWG05_20190	ENOG4105M5K	heptosyltransferase
GWG05_20195	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
GWG05_20200	ENOG4108MJ5	VirK protein
GWG05_20205	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
GWG05_20215	ENOG4105W0E	50S ribosomal protein L33
GWG05_20220	ENOG4105KDC	50s ribosomal protein l28
GWG05_20225	ENOG4105W5Q	DNA repair protein (RadC
GWG05_20230	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
GWG05_20235	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
GWG05_20240	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
GWG05_20250	ENOG4105D64	Mechanosensitive ion channel
GWG05_20260	ENOG4107QP8	phosphohexose isomerase
GWG05_20265	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
GWG05_20270	ENOG4105EMY	transcriptional regulator
GWG05_20280	ENOG4105CD5	CoA-binding domain protein
GWG05_20305	ENOG4108RR8	protoporphyrinogen oxidase
GWG05_20310	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GWG05_20315	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
GWG05_20320	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
GWG05_20325	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GWG05_20330	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GWG05_20335	ENOG4105CHU	acetyl-coa acetyltransferase
GWG05_20345	ENOG4105E0F	Histidine kinase
GWG05_20375	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
GWG05_20380	ENOG4105M4H	endoribonuclease L-psp
GWG05_20400	ENOG4108ZG0	Ompa motb domain protein
GWG05_20410	ENOG4105D3W	isochorismatase
GWG05_20415	ENOG4108R3E	Dna-3-methyladenine glycosylase i
GWG05_20420	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
GWG05_20425	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
GWG05_20430	ENOG4106J9S	Prophage
GWG05_20465	ENOG4105CIC	tryptophan-specific transport protein
GWG05_20470	ENOG4105CIC	tryptophan-specific transport protein
GWG05_20485	ENOG4105HEE	Binding Domain protein
GWG05_20495	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
GWG05_20500	ENOG4105CNW	domain protein
GWG05_20505	ENOG4108JUA	Transcriptional regulator
GWG05_20510	ENOG4105ETE	Transcriptional regulator (LacI family
GWG05_20515	ENOG4105CP9	extracellular ligand-binding receptor
GWG05_20520	ENOG4105C32	Amino acid ABC transporter (Permease)
GWG05_20525	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
GWG05_20530	ENOG4105C0Z	ABC transporter
GWG05_20535	ENOG4108IV0	ABC, transporter
GWG05_20550	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
GWG05_20565	ENOG4105W0Z	cytoplasmic protein
GWG05_20570	ENOG4107QK7	reductase
GWG05_20575	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
GWG05_20585	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
GWG05_20595	ENOG4105C1J	atp-dependent rna helicase
GWG05_20600	ENOG4105C9X	ppx gppa phosphatase
GWG05_20610	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
GWG05_20615	ENOG4105BZU	Histidine kinase
GWG05_20620	ENOG4105DGW	oligopeptidase A
GWG05_20625	ENOG4105D52	delta-aminolevulinic acid dehydratase
GWG05_20630	ENOG4105F8V	Hydrolase, tatD family
GWG05_20635	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
GWG05_20640	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
GWG05_20645	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
GWG05_20650	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
GWG05_20655	ENOG4105JC1	sterol-binding domain protein
GWG05_20660	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GWG05_20665	ENOG4105WMR	Protein CrcB homolog
GWG05_20670	ENOG4105DZC	cytosine deaminase
GWG05_20710	ENOG410822N	TonB family
GWG05_20715	ENOG4109015	Biopolymer transport protein exbD tolR
GWG05_20735	ENOG4105VJY	transcriptional regulator
GWG05_20745	ENOG4105C2X	Arabinose 5-phosphate isomerase
GWG05_20750	ENOG410804X	Transcriptional regulator
GWG05_20760	ENOG4107QMF	Sorbitol-6-phosphate dehydrogenase
GWG05_20765	ENOG4105VI0	Pts system, glucitol sorbitol-specific
GWG05_20770	ENOG4105DZY	Pts system, glucitol sorbitol-specific
GWG05_20775	ENOG410787A	Pts system, glucitol sorbitol-specific
GWG05_20790	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GWG05_20795	ENOG4107QP8	phosphohexose isomerase
GWG05_20800	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
GWG05_20870	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GWG05_20875	ENOG410804X	Transcriptional regulator
GWG05_20880	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GWG05_20885	ENOG4105EB3	Histidine kinase
GWG05_20895	ENOG4105CT7	inner membrane cred family protein
GWG05_20900	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GWG05_20905	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GWG05_20910	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GWG05_20915	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GWG05_20920	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GWG05_20925	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GWG05_20930	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GWG05_20935	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GWG05_20940	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
GWG05_20950	ENOG4105FA0	parb-like partition protein
GWG05_20955	ENOG4107QJE	Chromosome Partitioning Protein
GWG05_20960	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
GWG05_20965	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GWG05_20970	ENOG4105QTB	Flavodoxin
GWG05_20975	ENOG4105E0K	tonB-dependent siderophore receptor
GWG05_20980	ENOG4105IBP	Cyclic peptide transporter
GWG05_20985	ENOG4105E0A	ABC, transporter
GWG05_20990	ENOG4105J76	Periplasmic binding protein
GWG05_20995	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
GWG05_21000	ENOG4105CAF	HipA N-terminal domain protein
GWG05_21025	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GWG05_21030	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GWG05_21035	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
GWG05_21040	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GWG05_21045	ENOG4105VG0	50S ribosomal protein l34
GWG05_21050	ENOG4105CDA	abc transporter atp-binding protein
GWG05_21055	ENOG4105E5Q	amino acid AbC transporter
GWG05_21060	ENOG4105EAB	amino acid AbC transporter