locus-tag	class	description
GWG10_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GWG10_00010	COG0592	DNA-directed DNA polymerase activity
GWG10_00020	COG0187	DNA topoisomerase II activity
GWG10_00030	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GWG10_00035	COG0071	Belongs to the small heat shock protein (HSP20) family
GWG10_00040	COG0071	Belongs to the small heat shock protein (HSP20) family
GWG10_00045	COG3977	Valine--pyruvate aminotransferase
GWG10_00060	COG2814	Major facilitator Superfamily
GWG10_00065	COG0745	RESPONSE REGULATOR receiver
GWG10_00070	COG2205	protein histidine kinase activity
GWG10_00095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GWG10_00100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GWG10_00100	COG4191	Histidine kinase
GWG10_00105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GWG10_00110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GWG10_00115	COG1309	transcriptional regulator
GWG10_00145	COG0561	phosphatase activity
GWG10_00150	COG2267	carboxylic ester hydrolase activity
GWG10_00155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GWG10_00160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GWG10_00165	COG1758	RNA polymerase activity
GWG10_00175	COG0859	PFAM glycosyl transferase family 9
GWG10_00180	COG3642	lipopolysaccharide core region biosynthetic process
GWG10_00220	COG0589	response to stress
GWG10_00225	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GWG10_00230	COG3706	GGDEF domain
GWG10_00235	COG1528	Iron-storage protein
GWG10_00240	COG2081	HI0933 family
GWG10_00245	COG2223	nitrite transmembrane transporter activity
GWG10_00250	COG1280	lysine exporter protein (LysE YggA)
GWG10_00265	COG3188	usher protein
GWG10_00285	COG2205	protein histidine kinase activity
GWG10_00285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GWG10_00295	COG3275	phosphorelay sensor kinase activity
GWG10_00300	COG3279	Response regulator of the LytR AlgR family
GWG10_00305	COG2223	nitrite transmembrane transporter activity
GWG10_00310	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GWG10_00315	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GWG10_00365	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GWG10_00370	COG2166	iron-sulfur cluster assembly
GWG10_00375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GWG10_00395	COG1063	alcohol dehydrogenase
GWG10_00410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GWG10_00455	COG1609	Transcriptional regulator
GWG10_00475	COG1580	Controls the rotational direction of flagella during chemotaxis
GWG10_00480	COG3161	chorismate lyase activity
GWG10_00485	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GWG10_00490	COG2937	Belongs to the GPAT DAPAT family
GWG10_00495	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GWG10_00510	COG0534	Mate efflux family protein
GWG10_00515	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GWG10_00520	COG2205	protein histidine kinase activity
GWG10_00525	COG0745	RESPONSE REGULATOR receiver
GWG10_00535	COG1045	serine acetyltransferase
GWG10_00545	COG3074	FtsZ-dependent cytokinesis
GWG10_00550	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GWG10_00555	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GWG10_00555	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GWG10_00560	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GWG10_00595	COG1609	Transcriptional regulator
GWG10_00600	COG3250	beta-galactosidase activity
GWG10_00605	COG2731	YhcH YjgK YiaL family protein
GWG10_00610	COG0531	amino acid
GWG10_00615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GWG10_00620	COG0531	amino acid
GWG10_00625	COG0385	Bile acid
GWG10_00630	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GWG10_00655	COG0583	DNA-binding transcription factor activity
GWG10_00680	COG0210	DNA helicase
GWG10_00725	COG0583	DNA-binding transcription factor activity
GWG10_00770	COG1280	lysine exporter protein (LysE YggA)
GWG10_00780	COG2962	Rard protein
GWG10_00785	COG1012	belongs to the aldehyde dehydrogenase family
GWG10_00790	COG1396	sequence-specific DNA binding
GWG10_00805	COG0519	Catalyzes the synthesis of GMP from XMP
GWG10_00805	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GWG10_00815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GWG10_00835	COG1322	Protein conserved in bacteria
GWG10_00840	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GWG10_00845	COG0569	domain protein
GWG10_00850	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GWG10_00850	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GWG10_00855	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GWG10_00860	COG0242	peptide deformylase activity
GWG10_00870	COG0758	DNA mediated transformation
GWG10_00875	COG2922	Belongs to the Smg family
GWG10_00880	COG0551	DNA topoisomerase type I activity
GWG10_00885	COG0009	L-threonylcarbamoyladenylate synthase
GWG10_00890	COG0408	coproporphyrinogen oxidase activity
GWG10_00895	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GWG10_00900	COG2801	Transposase and inactivated derivatives
GWG10_00905	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GWG10_00930	COG3078	GTPase activator activity
GWG10_00940	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GWG10_00945	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GWG10_00955	COG3852	Histidine kinase
GWG10_00965	COG0174	glutamine synthetase
GWG10_00975	COG1295	ribonuclease BN
GWG10_00980	COG1490	D-aminoacyl-tRNA deacylase activity
GWG10_00990	COG0456	acetyltransferase
GWG10_01000	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GWG10_01005	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GWG10_01010	COG2610	gluconate transmembrane transporter activity
GWG10_01015	COG3265	gluconokinase activity
GWG10_01020	COG0129	dihydroxy-acid dehydratase activity
GWG10_01025	COG0800	Aldolase
GWG10_01040	COG1609	Transcriptional regulator
GWG10_01050	COG4942	peptidase
GWG10_01055	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GWG10_01060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GWG10_01065	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GWG10_01070	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GWG10_01075	COG0316	Belongs to the HesB IscA family
GWG10_01075	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GWG10_01080	COG1040	competence protein
GWG10_01085	COG0596	Alpha beta hydrolase
GWG10_01100	COG2183	response to ionizing radiation
GWG10_01105	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GWG10_01110	COG0745	RESPONSE REGULATOR receiver
GWG10_01115	COG2205	protein histidine kinase activity
GWG10_01125	COG0051	transcription antitermination factor activity, RNA binding
GWG10_01130	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GWG10_01135	COG0088	Forms part of the polypeptide exit tunnel
GWG10_01140	COG0089	rRNA binding
GWG10_01145	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GWG10_01150	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GWG10_01155	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GWG10_01160	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GWG10_01165	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GWG10_01170	COG0255	Belongs to the universal ribosomal protein uL29 family
GWG10_01175	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GWG10_01180	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GWG10_01185	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GWG10_01190	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GWG10_01195	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GWG10_01200	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GWG10_01205	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GWG10_01210	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GWG10_01215	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GWG10_01220	COG1841	ribosomal large subunit assembly
GWG10_01225	COG0200	Binds to the 23S rRNA
GWG10_01230	COG0201	protein transport
GWG10_01235	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GWG10_01240	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GWG10_01245	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GWG10_01250	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GWG10_01255	COG0202	RNA polymerase activity
GWG10_01260	COG0203	ribosomal protein L17
GWG10_01270	COG3328	transposase activity
GWG10_01325	COG2249	NAD(P)H dehydrogenase (quinone) activity
GWG10_01330	COG0583	DNA-binding transcription factor activity
GWG10_01335	COG4221	oxidoreductase activity
GWG10_01350	COG1770	oligopeptidase
GWG10_01355	COG2358	TRAP transporter, solute receptor (TAXI family
GWG10_01370	COG3714	YhhN family
GWG10_01385	COG0583	DNA-binding transcription factor activity
GWG10_01395	COG1301	dicarboxylic acid transport
GWG10_01405	COG2095	MarC family integral membrane protein
GWG10_01415	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GWG10_01425	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GWG10_01435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GWG10_01460	COG0742	ribosomal rna small subunit methyltransferase
GWG10_01465	COG0552	protein localization to endoplasmic reticulum
GWG10_01470	COG2884	Cell division ATP-binding protein ftsE
GWG10_01475	COG2177	Part of the ABC transporter FtsEX involved in
GWG10_01485	COG0288	reversible hydration of carbon dioxide
GWG10_01490	COG2188	Transcriptional regulator
GWG10_01495	COG1228	amidohydrolase
GWG10_01500	COG0010	Belongs to the arginase family
GWG10_01505	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GWG10_01510	COG2986	histidine ammonia-lyase
GWG10_01515	COG3385	transposase activity
GWG10_01520	COG0387	Pfam Sodium calcium exchanger
GWG10_01525	COG2200	EAL domain
GWG10_01540	COG3385	transposase activity
GWG10_01595	COG1459	type II secretion system
GWG10_01640	COG1077	Cell shape determining protein MreB Mrl
GWG10_01645	COG1792	Involved in formation and maintenance of cell shape
GWG10_01650	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GWG10_01655	COG0424	maF-like protein
GWG10_01660	COG1530	ribonuclease E activity
GWG10_01665	COG3164	Protein of unknown function
GWG10_01670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GWG10_01675	COG0312	modulator of DNA gyrase
GWG10_01690	COG0477	Major facilitator Superfamily
GWG10_01700	COG2321	neutral zinc metallopeptidase
GWG10_01735	COG0189	ligase activity
GWG10_01740	COG0642	Histidine kinase
GWG10_01745	COG0745	RESPONSE REGULATOR receiver
GWG10_01760	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GWG10_01765	COG0352	thiamine-phosphate diphosphorylase activity
GWG10_01770	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GWG10_01780	COG2022	thiamine diphosphate biosynthetic process
GWG10_01785	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GWG10_01790	COG2801	Transposase and inactivated derivatives
GWG10_01835	COG0110	maltose O-acetyltransferase activity
GWG10_01845	COG2203	Gaf domain
GWG10_01845	COG2199	diguanylate cyclase activity
GWG10_01850	COG3932	Exopolysaccharide synthesis, ExoD
GWG10_01870	COG1733	regulation of RNA biosynthetic process
GWG10_01900	COG2226	methyltransferase
GWG10_01910	COG1494	fructose-1,6-bisphosphatase
GWG10_01920	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GWG10_01925	COG5007	Belongs to the BolA IbaG family
GWG10_01935	COG2854	intermembrane phospholipid transfer
GWG10_01940	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GWG10_01945	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GWG10_01950	COG1127	ABC transporter
GWG10_01955	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GWG10_01955	COG0517	IMP dehydrogenase activity
GWG10_01960	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GWG10_01970	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GWG10_01975	COG1137	ATPase activity
GWG10_01980	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GWG10_01990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWG10_01995	COG1660	Displays ATPase and GTPase activities
GWG10_02000	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWG10_02020	COG3964	amidohydrolase
GWG10_02050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GWG10_02055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GWG10_02065	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GWG10_02070	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GWG10_02075	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GWG10_02080	COG0723	plastoquinol--plastocyanin reductase activity
GWG10_02085	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GWG10_02090	COG2857	Cytochrome c1
GWG10_02095	COG0625	glutathione transferase activity
GWG10_02100	COG2969	positive regulation of protein catabolic process
GWG10_02105	COG2823	Periplasmic or secreted lipoprotein
GWG10_02110	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GWG10_02115	COG0792	nuclease activity
GWG10_02120	COG3107	peptidoglycan biosynthetic process
GWG10_02125	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GWG10_02135	COG2001	Belongs to the MraZ family
GWG10_02140	COG0275	rRNA processing
GWG10_02145	COG3116	cell division
GWG10_02150	COG0768	penicillin binding
GWG10_02155	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GWG10_02160	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GWG10_02165	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GWG10_02170	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GWG10_02175	COG0772	Belongs to the SEDS family
GWG10_02180	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GWG10_02185	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GWG10_02190	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GWG10_02195	COG0849	cell division
GWG10_02200	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GWG10_02205	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GWG10_02215	COG0653	protein targeting
GWG10_02225	COG0494	nUDIX hydrolase
GWG10_02230	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GWG10_02235	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GWG10_02245	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GWG10_02250	COG1459	type II secretion system
GWG10_02255	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GWG10_02280	COG2186	Transcriptional regulator
GWG10_02285	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GWG10_02290	COG0508	dehydrogenase complex catalyzes the overall conversion of
GWG10_02295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GWG10_02305	COG0840	transmembrane signaling receptor activity
GWG10_02310	COG1752	Esterase of the alpha-beta hydrolase superfamily
GWG10_02315	COG1049	propionate catabolic process, 2-methylcitrate cycle
GWG10_02320	COG2200	EAL domain
GWG10_02330	COG1280	lysine exporter protein (LysE YggA)
GWG10_02340	COG0523	cobalamin synthesis protein
GWG10_02345	COG0477	Major facilitator Superfamily
GWG10_02360	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GWG10_02365	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GWG10_02410	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GWG10_02420	COG1546	Belongs to the CinA family
GWG10_02425	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GWG10_02430	COG2137	regulation of response to DNA damage stimulus
GWG10_02435	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GWG10_02440	COG0527	aspartate kinase activity
GWG10_02445	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GWG10_02480	COG1686	Belongs to the peptidase S11 family
GWG10_02485	COG0586	Pfam SNARE associated Golgi protein
GWG10_02490	COG1253	flavin adenine dinucleotide binding
GWG10_02495	COG0525	valine-tRNA ligase activity
GWG10_02500	COG2927	DNA polymerase III (CHI subunit)
GWG10_02505	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GWG10_02510	COG0795	lipopolysaccharide-transporting ATPase activity
GWG10_02515	COG0795	lipopolysaccharide-transporting ATPase activity
GWG10_02530	COG4974	Belongs to the 'phage' integrase family
GWG10_02600	COG0789	Transcriptional regulator
GWG10_02610	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GWG10_02630	COG2801	Transposase and inactivated derivatives
GWG10_02645	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GWG10_02655	COG3039	Transposase
GWG10_02715	COG2801	Transposase and inactivated derivatives
GWG10_02735	COG0004	ammonium transporteR
GWG10_02740	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GWG10_02750	COG4968	Prepilin-type N-terminal cleavage methylation domain
GWG10_02755	COG0084	hydrolase, TatD family'
GWG10_02760	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GWG10_02770	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GWG10_02775	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GWG10_02780	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GWG10_02790	COG4520	surface antigen
GWG10_02795	COG5002	protein histidine kinase activity
GWG10_02795	COG5001	Diguanylate cyclase
GWG10_02795	COG3447	MASE1 domain protein
GWG10_02805	COG0560	Phosphoserine phosphatase
GWG10_02820	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GWG10_02830	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GWG10_02835	COG0776	regulation of translation
GWG10_02850	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GWG10_02855	COG0735	belongs to the Fur family
GWG10_02875	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GWG10_02880	COG0513	Belongs to the DEAD box helicase family
GWG10_02885	COG3022	response to hydroperoxide
GWG10_02890	COG2805	Type II/IV secretion system protein
GWG10_02900	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GWG10_02905	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GWG10_02910	COG0762	integral membrane protein
GWG10_02915	COG1872	DUF167
GWG10_02935	COG3112	Uncharacterised protein family (UPF0231)
GWG10_02940	COG3835	regulator
GWG10_02945	COG2610	gluconate transmembrane transporter activity
GWG10_02950	COG1929	Belongs to the glycerate kinase type-1 family
GWG10_02965	COG0583	DNA-binding transcription factor activity
GWG10_02970	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GWG10_02985	COG0347	Belongs to the P(II) protein family
GWG10_03000	COG3842	ATPase activity
GWG10_03005	COG2837	iron assimilation
GWG10_03010	COG1438	arginine binding
GWG10_03015	COG1126	abc transporter atp-binding protein
GWG10_03020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GWG10_03025	COG4215	(ABC) transporter
GWG10_03030	COG4160	amino acid transport
GWG10_03035	COG0039	L-malate dehydrogenase activity
GWG10_03040	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GWG10_03045	COG1017	nitric oxide dioxygenase activity
GWG10_03045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GWG10_03055	COG4536	flavin adenine dinucleotide binding
GWG10_03060	COG4137	Cytochrome C assembly protein
GWG10_03065	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GWG10_03070	COG0228	four-way junction DNA binding
GWG10_03075	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GWG10_03080	COG0336	Belongs to the RNA methyltransferase TrmD family
GWG10_03085	COG0335	large ribosomal subunit rRNA binding
GWG10_03100	COG1051	belongs to the nudix hydrolase family
GWG10_03110	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GWG10_03115	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GWG10_03120	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GWG10_03130	COG0583	DNA-binding transcription factor activity
GWG10_03135	COG0640	Transcriptional regulator
GWG10_03140	COG0268	Binds directly to 16S ribosomal RNA
GWG10_03145	COG0728	peptidoglycan biosynthetic process
GWG10_03150	COG0196	riboflavin kinase activity
GWG10_03155	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GWG10_03160	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GWG10_03165	COG1047	Peptidyl-prolyl cis-trans
GWG10_03170	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GWG10_03175	COG4968	Prepilin-type N-terminal cleavage methylation domain
GWG10_03235	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GWG10_03235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GWG10_03250	COG1854	S-ribosylhomocysteine lyase activity
GWG10_03255	COG3706	GGDEF domain
GWG10_03260	COG0557	exoribonuclease II activity
GWG10_03265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GWG10_03275	COG2153	protein acetylation
GWG10_03285	COG1914	H( )-stimulated, divalent metal cation uptake system
GWG10_03290	COG0360	Binds together with S18 to 16S ribosomal RNA
GWG10_03295	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GWG10_03300	COG0359	binds to the 23S rRNA
GWG10_03340	COG1238	metal cluster binding
GWG10_03345	COG0612	Peptidase, M16
GWG10_03350	COG2918	glutathione biosynthetic process
GWG10_03355	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GWG10_03360	COG1027	Aspartate ammonia-lyase
GWG10_03365	COG3030	protein affecting phage T7 exclusion by the F plasmid
GWG10_03370	COG0534	Mate efflux family protein
GWG10_03375	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GWG10_03380	COG0459	protein refolding
GWG10_03400	COG0564	pseudouridine synthase activity
GWG10_03405	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GWG10_03435	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GWG10_03445	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GWG10_03450	COG4208	sulfate ABC transporter
GWG10_03455	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GWG10_03460	COG0583	DNA-binding transcription factor activity
GWG10_03465	COG3397	chitin binding
GWG10_03495	COG1328	CTP reductase activity
GWG10_03500	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GWG10_03515	COG1448	Aminotransferase
GWG10_03520	COG2194	sulfuric ester hydrolase activity
GWG10_03540	COG1215	transferase activity, transferring glycosyl groups
GWG10_03545	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GWG10_03550	COG3118	belongs to the thioredoxin family
GWG10_03550	COG0457	Tetratricopeptide repeat
GWG10_03585	COG0513	Belongs to the DEAD box helicase family
GWG10_03590	COG0840	transmembrane signaling receptor activity
GWG10_03600	COG4166	transmembrane transport
GWG10_03615	COG1024	Enoyl-CoA hydratase
GWG10_03630	COG4221	oxidoreductase activity
GWG10_03635	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GWG10_03640	COG0442	prolyl-tRNA aminoacylation
GWG10_03645	COG0840	transmembrane signaling receptor activity
GWG10_03650	COG0632	four-way junction helicase activity
GWG10_03655	COG2255	four-way junction helicase activity
GWG10_03665	COG1271	oxidase subunit
GWG10_03670	COG1294	oxidase, subunit
GWG10_03675	COG4890	Cyd operon protein YbgT
GWG10_03680	COG3790	cyd operon protein YbgE
GWG10_03685	COG0824	Thioesterase
GWG10_03690	COG0811	peptide transport
GWG10_03705	COG0823	Involved in the tonB-independent uptake of proteins
GWG10_03710	COG2885	chlorophyll binding
GWG10_03715	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GWG10_03790	COG0840	transmembrane signaling receptor activity
GWG10_03795	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GWG10_03805	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GWG10_03810	COG1640	4-alpha-glucanotransferase
GWG10_03815	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GWG10_03845	COG2130	NADP-dependent
GWG10_03850	COG1846	Transcriptional regulator
GWG10_03880	COG0561	phosphatase activity
GWG10_03895	COG0733	neurotransmitter:sodium symporter activity
GWG10_03900	COG0733	neurotransmitter:sodium symporter activity
GWG10_03915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GWG10_03930	COG1794	racemase activity, acting on amino acids and derivatives
GWG10_03940	COG1022	Amp-dependent synthetase and ligase
GWG10_03950	COG0456	acetyltransferase
GWG10_03965	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GWG10_03970	COG5002	protein histidine kinase activity
GWG10_03970	COG5001	Diguanylate cyclase
GWG10_04000	COG1902	pentaerythritol trinitrate reductase activity
GWG10_04015	COG2957	Belongs to the agmatine deiminase family
GWG10_04020	COG0154	amidase activity
GWG10_04025	COG2801	Transposase and inactivated derivatives
GWG10_04035	COG3039	Transposase
GWG10_04070	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
GWG10_04080	COG1136	(ABC) transporter
GWG10_04080	COG0577	efflux transmembrane transporter activity
GWG10_04085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GWG10_04090	COG0745	RESPONSE REGULATOR receiver
GWG10_04095	COG2205	protein histidine kinase activity
GWG10_04145	COG1280	lysine exporter protein (LysE YggA)
GWG10_04150	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GWG10_04165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GWG10_04195	COG0745	RESPONSE REGULATOR receiver
GWG10_04200	COG3104	oligopeptide transport
GWG10_04205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GWG10_04210	COG1555	photosystem II stabilization
GWG10_04220	COG2350	Protein conserved in bacteria
GWG10_04225	COG2917	probably involved in intracellular septation
GWG10_04230	COG0076	glutamate decarboxylase activity
GWG10_04235	COG1272	protein, Hemolysin III
GWG10_04240	COG0569	domain protein
GWG10_04240	COG2985	domain, Protein
GWG10_04250	COG0477	Major facilitator Superfamily
GWG10_04255	COG0583	DNA-binding transcription factor activity
GWG10_04260	COG3227	Zinc metalloprotease (Elastase)
GWG10_04265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GWG10_04270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GWG10_04280	COG2731	YhcH YjgK YiaL family protein
GWG10_04290	COG0668	transmembrane transport
GWG10_04300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GWG10_04320	COG3039	Transposase
GWG10_04355	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GWG10_04365	COG0488	(ABC) transporter
GWG10_04370	COG0516	GMP reductase activity
GWG10_04370	COG0517	IMP dehydrogenase activity
GWG10_04380	COG0835	chemotaxis
GWG10_04380	COG0784	Response regulator, receiver
GWG10_04385	COG2755	lipolytic protein G-D-S-L family
GWG10_04390	COG4181	ATPase activity
GWG10_04395	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GWG10_04400	COG1090	epimerase
GWG10_04405	COG2200	EAL domain
GWG10_04410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GWG10_04415	COG2234	aminopeptidase activity
GWG10_04415	COG4935	Belongs to the peptidase S8 family
GWG10_04420	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GWG10_04425	COG3171	Protein conserved in bacteria
GWG10_04430	COG2066	Belongs to the glutaminase family
GWG10_04435	COG2897	thiosulfate sulfurtransferase activity
GWG10_04445	COG1132	(ABC) transporter
GWG10_04470	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
GWG10_04475	COG5001	Diguanylate cyclase
GWG10_04475	COG3300	MHYT domain
GWG10_04495	COG4628	conserved protein (DUF2132)
GWG10_04500	COG0688	phosphatidylethanolamine metabolic process
GWG10_04505	COG1162	GTPase activity
GWG10_04510	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GWG10_04545	COG1278	Cold shock
GWG10_04555	COG0840	transmembrane signaling receptor activity
GWG10_04560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GWG10_04610	COG0848	biopolymer transport protein
GWG10_04615	COG0811	peptide transport
GWG10_04620	COG0811	peptide transport
GWG10_04630	COG4206	TonB-dependent receptor
GWG10_04635	COG4174	ABC transporter (Permease)
GWG10_04640	COG4239	(ABC) transporter, permease
GWG10_04650	COG0444	Belongs to the ABC transporter superfamily
GWG10_04655	COG4608	Belongs to the ABC transporter superfamily
GWG10_04665	COG2195	Cleaves the N-terminal amino acid of tripeptides
GWG10_04675	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GWG10_04695	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GWG10_04725	COG0243	molybdopterin cofactor binding
GWG10_04730	COG1648	precorrin-2 dehydrogenase activity
GWG10_04730	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GWG10_04740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GWG10_04740	COG1116	anion transmembrane transporter activity
GWG10_04745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GWG10_04750	COG1116	anion transmembrane transporter activity
GWG10_04755	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GWG10_04755	COG2146	nitrite reductase [NAD(P)H] activity
GWG10_04760	COG2146	nitrite reductase [NAD(P)H] activity
GWG10_04760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GWG10_04765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GWG10_04770	COG2313	pseudouridylate synthase activity
GWG10_04790	COG0521	Mo-molybdopterin cofactor biosynthetic process
GWG10_04800	COG2966	Psort location CytoplasmicMembrane, score
GWG10_04805	COG3610	response to peptide
GWG10_04815	COG4175	Glycine betaine
GWG10_04820	COG4176	ABC-type proline glycine betaine transport system permease component
GWG10_04825	COG2113	Glycine betaine
GWG10_04835	COG0175	sulfate reduction
GWG10_04840	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GWG10_04850	COG0384	phenazine biosynthesis protein PhzF
GWG10_04855	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GWG10_04870	COG0786	glutamate:sodium symporter activity
GWG10_04875	COG0252	asparaginase activity
GWG10_04880	COG3139	Protein of unknown function (DUF1315)
GWG10_04900	COG0616	signal peptide processing
GWG10_04905	COG1902	pentaerythritol trinitrate reductase activity
GWG10_04905	COG0446	pyridine nucleotide-disulphide oxidoreductase
GWG10_04910	COG0778	Nitroreductase
GWG10_04925	COG2264	protein methyltransferase activity
GWG10_04930	COG0604	alcohol dehydrogenase
GWG10_04935	COG0583	DNA-binding transcription factor activity
GWG10_04940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWG10_04940	COG1263	PTS System
GWG10_04940	COG2190	(PTS) system
GWG10_04945	COG4145	pantothenate transmembrane transporter activity
GWG10_04950	COG3924	membrane
GWG10_04955	COG0439	Biotin carboxylase
GWG10_04960	COG0511	ligase activity, forming carbon-carbon bonds
GWG10_04965	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GWG10_04970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GWG10_04985	COG3381	protein complex oligomerization
GWG10_04995	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GWG10_05005	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GWG10_05010	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GWG10_05010	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GWG10_05025	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GWG10_05030	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GWG10_05035	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GWG10_05040	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GWG10_05045	COG4172	Belongs to the ABC transporter superfamily
GWG10_05065	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GWG10_05070	COG0142	geranyltranstransferase activity
GWG10_05075	COG1722	exodeoxyribonuclease VII activity
GWG10_05080	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GWG10_05085	COG1360	Flagellar Motor Protein
GWG10_05100	COG1534	Rna-binding protein
GWG10_05105	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GWG10_05115	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GWG10_05120	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GWG10_05125	COG0149	triose-phosphate isomerase activity
GWG10_05130	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GWG10_05145	COG0779	Required for maturation of 30S ribosomal subunits
GWG10_05150	COG0195	Participates in both transcription termination and antitermination
GWG10_05155	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GWG10_05160	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GWG10_05165	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GWG10_05170	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GWG10_05175	COG1185	polyribonucleotide nucleotidyltransferase activity
GWG10_05180	COG2211	Major facilitator Superfamily
GWG10_05185	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GWG10_05190	COG1422	Protein of unknown function (DUF1090)
GWG10_05195	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GWG10_05215	COG0312	modulator of DNA gyrase
GWG10_05220	COG0312	modulator of DNA gyrase
GWG10_05230	COG4974	Belongs to the 'phage' integrase family
GWG10_05235	COG1970	mechanosensitive ion channel activity
GWG10_05245	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GWG10_05250	COG0789	Transcriptional regulator
GWG10_05265	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GWG10_05275	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GWG10_05280	COG0321	lipoyl(octanoyl) transferase activity
GWG10_05285	COG2921	Belongs to the UPF0250 family
GWG10_05290	COG1686	Belongs to the peptidase S11 family
GWG10_05295	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GWG10_05300	COG2951	lytic endotransglycosylase activity
GWG10_05305	COG0772	Belongs to the SEDS family
GWG10_05310	COG0768	penicillin binding
GWG10_05315	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GWG10_05320	COG0799	negative regulation of ribosome biogenesis
GWG10_05325	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GWG10_05350	COG0495	leucyl-tRNA aminoacylation
GWG10_05355	COG2888	peptidyl-tyrosine sulfation
GWG10_05360	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GWG10_05365	COG4535	Mg2 and Co2 transporter CorC
GWG10_05370	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GWG10_05375	COG1702	phosphate starvation-inducible protein PhoH
GWG10_05380	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GWG10_05385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GWG10_05390	COG1335	isochorismatase
GWG10_05395	COG1278	Cold shock
GWG10_05410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GWG10_05415	COG2199	diguanylate cyclase activity
GWG10_05425	COG2199	diguanylate cyclase activity
GWG10_05435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GWG10_05450	COG1464	Belongs to the NlpA lipoprotein family
GWG10_05455	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GWG10_05460	COG2011	ABC-type metal ion transport system permease component
GWG10_05465	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GWG10_05475	COG0516	GMP reductase activity
GWG10_05480	COG0189	ligase activity
GWG10_05480	COG4067	protein conserved in archaea
GWG10_05500	COG0300	oxidoreductase activity
GWG10_05520	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GWG10_05525	COG3214	Protein conserved in bacteria
GWG10_05540	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GWG10_05545	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GWG10_05550	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GWG10_05555	COG1053	succinate dehydrogenase
GWG10_05565	COG0584	glycerophosphoryl diester phosphodiesterase
GWG10_05570	COG1511	domain protein
GWG10_05570	COG3264	Mechanosensitive ion channel
GWG10_05580	COG0739	heme binding
GWG10_05595	COG0583	DNA-binding transcription factor activity
GWG10_05610	COG0583	DNA-binding transcription factor activity
GWG10_05615	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GWG10_05645	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GWG10_05650	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GWG10_05660	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GWG10_05665	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GWG10_05670	COG0546	phosphoglycolate phosphatase activity
GWG10_05675	COG0180	Tryptophanyl-tRNA synthetase
GWG10_05690	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GWG10_05700	COG1012	belongs to the aldehyde dehydrogenase family
GWG10_05715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GWG10_05740	COG0471	metal ion transport
GWG10_05740	COG0490	domain, Protein
GWG10_05790	COG0012	GTP binding
GWG10_05795	COG0193	aminoacyl-tRNA hydrolase activity
GWG10_05800	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GWG10_05810	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GWG10_05815	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GWG10_05820	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GWG10_05825	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GWG10_05830	COG2890	protein-(glutamine-N5) methyltransferase activity
GWG10_05840	COG2912	Transglutaminase-like superfamily
GWG10_05845	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GWG10_05850	COG1301	dicarboxylic acid transport
GWG10_05860	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GWG10_05875	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GWG10_05880	COG1115	amino acid carrier protein
GWG10_05900	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GWG10_05910	COG0189	ligase activity
GWG10_05915	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GWG10_05925	COG3091	SprT-like family
GWG10_05940	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GWG10_05955	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GWG10_05960	COG0739	heme binding
GWG10_05965	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GWG10_05970	COG3385	transposase activity
GWG10_05985	COG1881	PFAM PEBP family protein
GWG10_05995	COG0583	DNA-binding transcription factor activity
GWG10_06005	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GWG10_06015	COG0583	DNA-binding transcription factor activity
GWG10_06020	COG1028	Short-chain dehydrogenase reductase Sdr
GWG10_06025	COG0616	signal peptide processing
GWG10_06030	COG3724	N-succinylarginine dihydrolase activity
GWG10_06045	COG0840	transmembrane signaling receptor activity
GWG10_06055	COG2971	BadF BadG BcrA BcrD
GWG10_06065	COG4608	Belongs to the ABC transporter superfamily
GWG10_06070	COG0444	Belongs to the ABC transporter superfamily
GWG10_06075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GWG10_06090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GWG10_06105	COG0798	PFAM Bile acid sodium symporter
GWG10_06110	COG1393	Belongs to the ArsC family
GWG10_06125	COG1677	Flagellar hook-basal body complex protein FliE
GWG10_06135	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GWG10_06190	COG1684	flagellar biosynthetic protein fliR
GWG10_06200	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GWG10_06225	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GWG10_06230	COG0643	Histidine kinase
GWG10_06230	COG2198	Histidine kinase
GWG10_06230	COG0784	Response regulator, receiver
GWG10_06235	COG2201	protein-glutamate methylesterase activity
GWG10_06240	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GWG10_06245	COG1360	Flagellar Motor Protein
GWG10_06250	COG1192	Involved in chromosome partitioning
GWG10_06260	COG0835	chemotaxis
GWG10_06275	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GWG10_06280	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GWG10_06285	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GWG10_06290	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GWG10_06295	COG1138	Cytochrome C-type biogenesis protein
GWG10_06300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GWG10_06310	COG0457	Tetratricopeptide repeat
GWG10_06325	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GWG10_06330	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GWG10_06330	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GWG10_06345	COG0259	pyridoxamine-phosphate oxidase activity
GWG10_06375	COG3153	acetyltransferase
GWG10_06390	COG0800	Aldolase
GWG10_06460	COG5642	Protein of unknown function (DUF2384)
GWG10_06465	COG2850	peptidyl-arginine hydroxylation
GWG10_06570	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GWG10_06575	COG2867	negative regulation of translational initiation
GWG10_06585	COG0702	epimerase
GWG10_06590	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GWG10_06715	COG0640	Transcriptional regulator
GWG10_06730	COG4383	Mu-like prophage protein gp29
GWG10_06750	COG4388	Caudovirus prohead serine protease
GWG10_06755	COG4397	Mu-like prophage major head subunit gpT
GWG10_06840	COG0564	pseudouridine synthase activity
GWG10_06845	COG1957	nucleoside hydrolase
GWG10_06870	COG1280	lysine exporter protein (LysE YggA)
GWG10_06880	COG3263	regulation of cellular component size
GWG10_06890	COG1876	peptidase activity
GWG10_06895	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GWG10_06900	COG1393	Belongs to the ArsC family
GWG10_06905	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GWG10_06920	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GWG10_06935	COG3069	C4-dicarboxylate transmembrane transporter activity
GWG10_06940	COG1473	amidohydrolase
GWG10_06950	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GWG10_06955	COG0017	Asparaginyl-tRNA synthetase
GWG10_06975	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GWG10_06980	COG0156	8-amino-7-oxononanoate synthase activity
GWG10_06985	COG2226	methyltransferase
GWG10_06985	COG1073	alpha beta
GWG10_06990	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GWG10_06995	COG0501	Belongs to the peptidase M48B family
GWG10_07000	COG3217	Mosc domain protein beta barrel domain protein
GWG10_07000	COG3217	Mosc domain protein beta barrel domain protein
GWG10_07000	COG0633	Ferredoxin
GWG10_07000	COG0633	Ferredoxin
GWG10_07010	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GWG10_07010	COG1013	pyruvate-flavodoxin oxidoreductase activity
GWG10_07010	COG0674	pyruvate-flavodoxin oxidoreductase activity
GWG10_07010	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GWG10_07015	COG2841	Protein conserved in bacteria
GWG10_07025	COG0534	Mate efflux family protein
GWG10_07060	COG1309	transcriptional regulator
GWG10_07075	COG0791	NLP P60 protein
GWG10_07080	COG0583	DNA-binding transcription factor activity
GWG10_07105	COG0500	methyltransferase
GWG10_07110	COG4106	trans-aconitate 2-methyltransferase activity
GWG10_07115	COG1801	Protein of unknown function DUF72
GWG10_07125	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GWG10_07130	COG0217	transcriptional regulatory protein
GWG10_07135	COG2194	sulfuric ester hydrolase activity
GWG10_07140	COG1940	carbohydrate kinase activity
GWG10_07140	COG1846	Transcriptional regulator
GWG10_07145	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GWG10_07150	COG0363	glucosamine-6-phosphate deaminase activity
GWG10_07155	COG1263	PTS System
GWG10_07155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWG10_07155	COG2190	(PTS) system
GWG10_07165	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GWG10_07170	COG0735	belongs to the Fur family
GWG10_07180	COG0716	FMN binding
GWG10_07195	COG0596	Alpha beta hydrolase
GWG10_07200	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GWG10_07205	COG0033	Phosphoglucomutase
GWG10_07215	COG1846	Transcriptional regulator
GWG10_07220	COG2951	lytic endotransglycosylase activity
GWG10_07225	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GWG10_07230	COG4136	ATPase activity
GWG10_07240	COG4134	Bacterial extracellular solute-binding protein
GWG10_07245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GWG10_07250	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GWG10_07260	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GWG10_07270	COG0729	surface antigen
GWG10_07275	COG2911	Protein conserved in bacteria
GWG10_07295	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GWG10_07305	COG0741	lytic transglycosylase activity
GWG10_07320	COG1607	acyl-coa hydrolase
GWG10_07335	COG0741	lytic transglycosylase activity
GWG10_07335	COG1388	LysM domain
GWG10_07340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GWG10_07345	COG2226	methyltransferase
GWG10_07350	COG0328	RNA-DNA hybrid ribonuclease activity
GWG10_07355	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GWG10_07375	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GWG10_07380	COG0121	glutamine amidotransferase
GWG10_07390	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GWG10_07415	COG2197	response regulator
GWG10_07420	COG3850	Histidine kinase
GWG10_07425	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GWG10_07430	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
GWG10_07430	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GWG10_07440	COG0243	molybdopterin cofactor binding
GWG10_07445	COG0437	4 iron, 4 sulfur cluster binding
GWG10_07450	COG0348	domain, Protein
GWG10_07460	COG3005	denitrification pathway
GWG10_07465	COG0521	Mo-molybdopterin cofactor biosynthetic process
GWG10_07470	COG0315	cyclic pyranopterin monophosphate synthase activity
GWG10_07475	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GWG10_07480	COG0314	molybdopterin synthase activity
GWG10_07495	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GWG10_07500	COG2267	carboxylic ester hydrolase activity
GWG10_07505	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GWG10_07510	COG0303	'Molybdopterin
GWG10_07515	COG0302	gtp cyclohydrolase
GWG10_07525	COG0675	Transposase, IS605 OrfB family
GWG10_07585	COG4644	lycopene metabolic process
GWG10_07600	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GWG10_07610	COG0583	DNA-binding transcription factor activity
GWG10_07625	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GWG10_07640	COG2195	Cleaves the N-terminal amino acid of tripeptides
GWG10_07645	COG1166	arginine decarboxylase activity
GWG10_07650	COG3385	transposase activity
GWG10_07695	COG0675	Transposase, IS605 OrfB family
GWG10_07705	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GWG10_07710	COG1187	pseudouridine synthase activity
GWG10_07715	COG2807	transmembrane transport
GWG10_07725	COG0583	DNA-binding transcription factor activity
GWG10_07745	COG2979	Protein of unknown function (DUF533)
GWG10_07755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GWG10_07760	COG1271	oxidase subunit
GWG10_07765	COG1294	oxidase, subunit
GWG10_07775	COG2814	Major facilitator Superfamily
GWG10_07780	COG0656	L-ascorbic acid biosynthetic process
GWG10_07800	COG0583	DNA-binding transcription factor activity
GWG10_07805	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GWG10_07810	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GWG10_07825	COG2271	Major facilitator Superfamily
GWG10_07830	COG1349	DNA-binding transcription factor activity
GWG10_07840	COG0584	glycerophosphoryl diester phosphodiesterase
GWG10_07845	COG3385	transposase activity
GWG10_07850	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GWG10_07855	COG1605	Chorismate mutase
GWG10_07855	COG0287	Prephenate dehydrogenase
GWG10_07865	COG3085	chromosome segregation
GWG10_07870	COG4574	serine-type endopeptidase inhibitor activity
GWG10_07890	COG1770	oligopeptidase
GWG10_07895	COG4771	TonB-dependent receptor
GWG10_07900	COG3083	sulfuric ester hydrolase activity
GWG10_07905	COG3082	Protein of unknown function (DUF1414)
GWG10_07910	COG3081	Nucleoid-associated protein
GWG10_07920	COG1175	transmembrane transport
GWG10_07925	COG3833	ABC-type maltose transport systems, permease component
GWG10_07930	COG3842	ATPase activity
GWG10_07940	COG0596	Alpha beta hydrolase
GWG10_07955	COG0425	Belongs to the sulfur carrier protein TusA family
GWG10_07960	COG4783	chaperone-mediated protein folding
GWG10_07970	COG1393	Belongs to the ArsC family
GWG10_07985	COG0675	Transposase, IS605 OrfB family
GWG10_07995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GWG10_08000	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GWG10_08005	COG2431	L-lysine efflux transmembrane transporter activity
GWG10_08015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GWG10_08025	COG4160	amino acid transport
GWG10_08040	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GWG10_08050	COG0446	pyridine nucleotide-disulphide oxidoreductase
GWG10_08055	COG0628	permease
GWG10_08060	COG2373	Large extracellular alpha-helical protein
GWG10_08065	COG4953	penicillin-binding protein 1C
GWG10_08075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GWG10_08075	COG0301	tRNA thio-modification
GWG10_08090	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GWG10_08095	COG1334	flagellar protein FlaG
GWG10_08125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GWG10_08135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GWG10_08150	COG0346	lactoylglutathione lyase activity
GWG10_08155	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GWG10_08160	COG4660	Part of a membrane complex involved in electron transport
GWG10_08165	COG4659	FMN binding
GWG10_08170	COG4658	electron transport chain
GWG10_08180	COG2878	Part of a membrane complex involved in electron transport
GWG10_08185	COG4657	Part of a membrane complex involved in electron transport
GWG10_08190	COG0675	Transposase, IS605 OrfB family
GWG10_08200	COG0697	spore germination
GWG10_08230	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GWG10_08245	COG0436	Aminotransferase
GWG10_08255	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GWG10_08260	COG2027	D-alanyl-D-alanine carboxypeptidase
GWG10_08265	COG1061	Type III restriction enzyme res subunit
GWG10_08270	COG1566	PFAM secretion protein HlyD family protein
GWG10_08285	COG0675	Transposase, IS605 OrfB family
GWG10_08290	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GWG10_08290	COG3264	Mechanosensitive ion channel
GWG10_08295	COG1966	Carbon starvation protein
GWG10_08300	COG3279	Response regulator of the LytR AlgR family
GWG10_08305	COG3275	phosphorelay sensor kinase activity
GWG10_08315	COG1012	belongs to the aldehyde dehydrogenase family
GWG10_08315	COG1454	alcohol dehydrogenase
GWG10_08320	COG2095	MarC family integral membrane protein
GWG10_08330	COG0601	transmembrane transport
GWG10_08335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GWG10_08340	COG0444	Belongs to the ABC transporter superfamily
GWG10_08350	COG0861	Integral membrane protein TerC family
GWG10_08355	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GWG10_08365	COG1301	dicarboxylic acid transport
GWG10_08385	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GWG10_08390	COG0582	viral genome integration into host DNA
GWG10_08420	COG2974	May be involved in recombination
GWG10_08445	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GWG10_08730	COG0537	adenosine 5'-monophosphoramidase activity
GWG10_08765	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GWG10_08770	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GWG10_08785	COG2354	Protein conserved in bacteria
GWG10_08790	COG1164	Oligoendopeptidase f
GWG10_08795	COG1164	Oligoendopeptidase f
GWG10_08800	COG3150	esterase
GWG10_08805	COG1252	NADH dehydrogenase
GWG10_08810	COG0393	Putative heavy-metal-binding
GWG10_08815	COG1368	sulfuric ester hydrolase activity
GWG10_08825	COG0527	aspartate kinase activity
GWG10_08830	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GWG10_08830	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GWG10_08835	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GWG10_08860	COG0583	DNA-binding transcription factor activity
GWG10_08865	COG1620	l-lactate permease
GWG10_08870	COG0247	lactate metabolic process
GWG10_08875	COG1139	Iron-sulfur cluster binding protein
GWG10_08900	COG1136	(ABC) transporter
GWG10_08920	COG2814	Major facilitator Superfamily
GWG10_08945	COG0672	)-iron permease
GWG10_08980	COG2308	Evidence 4 Homologs of previously reported genes of
GWG10_08995	COG0659	secondary active sulfate transmembrane transporter activity
GWG10_09015	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GWG10_09020	COG0326	Molecular chaperone. Has ATPase activity
GWG10_09025	COG0563	adenylate kinase activity
GWG10_09030	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GWG10_09035	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GWG10_09040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GWG10_09045	COG0840	transmembrane signaling receptor activity
GWG10_09060	COG3300	MHYT domain
GWG10_09060	COG5001	Diguanylate cyclase
GWG10_09085	COG1021	2,3-dihydroxybenzoate-AMP ligase
GWG10_09090	COG1535	isochorismatase
GWG10_09090	COG3433	isochorismatase activity
GWG10_09095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GWG10_09100	COG1028	Short-chain dehydrogenase reductase Sdr
GWG10_09110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GWG10_09125	COG1120	ATPase activity
GWG10_09130	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GWG10_09135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GWG10_09140	COG4771	TonB-dependent receptor
GWG10_09180	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GWG10_09185	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GWG10_09190	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GWG10_09195	COG0861	Integral membrane protein TerC family
GWG10_09210	COG1022	Amp-dependent synthetase and ligase
GWG10_09215	COG0295	cytidine deaminase activity
GWG10_09220	COG1346	cytolysis
GWG10_09225	COG1380	Effector of murein hydrolase LrgA
GWG10_09230	COG3345	alpha-galactosidase
GWG10_09240	COG2925	Exonuclease
GWG10_09245	COG0582	viral genome integration into host DNA
GWG10_09335	COG1846	Transcriptional regulator
GWG10_09350	COG3646	Phage regulatory protein
GWG10_09400	COG4626	Terminase
GWG10_09400	COG1802	Transcriptional regulator
GWG10_09510	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GWG10_09515	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GWG10_09515	COG0392	lysyltransferase activity
GWG10_09530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GWG10_09535	COG0436	Aminotransferase
GWG10_09540	COG0583	DNA-binding transcription factor activity
GWG10_09545	COG2160	L-arabinose isomerase activity
GWG10_09555	COG1069	ribulokinase activity
GWG10_09560	COG1879	ABC-type sugar transport system periplasmic component
GWG10_09565	COG1129	ABC transporter
GWG10_09570	COG1172	Belongs to the binding-protein-dependent transport system permease family
GWG10_09580	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GWG10_09585	COG0254	rRNA binding
GWG10_09600	COG1451	nucleotide metabolic process
GWG10_09615	COG3069	C4-dicarboxylate transmembrane transporter activity
GWG10_09625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GWG10_09625	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GWG10_09630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GWG10_09650	COG2009	succinate dehydrogenase
GWG10_09655	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GWG10_09670	COG0567	Dehydrogenase, E1 component
GWG10_09675	COG0508	dehydrogenase complex catalyzes the overall conversion of
GWG10_09680	COG0045	succinate-CoA ligase (ADP-forming) activity
GWG10_09685	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GWG10_09690	COG2801	Transposase and inactivated derivatives
GWG10_09705	COG2983	Belongs to the UPF0260 family
GWG10_09710	COG1882	Formate acetyltransferase
GWG10_09715	COG2116	formate transmembrane transporter activity
GWG10_09720	COG1944	ATP diphosphatase activity
GWG10_09730	COG2076	Multidrug Resistance protein
GWG10_09735	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GWG10_09740	COG1278	Cold shock
GWG10_09745	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GWG10_09750	COG0542	response to heat
GWG10_09755	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GWG10_09760	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GWG10_09765	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GWG10_09770	COG3134	Outer membrane lipoprotein
GWG10_09775	COG3706	GGDEF domain
GWG10_09780	COG0492	ferredoxin-NADP+ reductase activity
GWG10_09785	COG0686	Belongs to the AlaDH PNT family
GWG10_09795	COG0531	amino acid
GWG10_09795	COG1674	ftsk spoiiie
GWG10_09800	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GWG10_09805	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GWG10_09810	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GWG10_09815	COG1286	toxin biosynthetic process
GWG10_09820	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GWG10_09825	COG2723	6-phospho-beta-galactosidase activity
GWG10_09830	COG1263	PTS System
GWG10_09830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWG10_09835	COG1609	Transcriptional regulator
GWG10_09845	COG4172	Belongs to the ABC transporter superfamily
GWG10_09855	COG4171	peptide transport system, permease
GWG10_09870	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GWG10_09875	COG1842	Phage shock protein A
GWG10_09890	COG3106	COG3106 Predicted ATPase
GWG10_09895	COG3768	UPF0283 membrane protein
GWG10_09905	COG2154	pterin-4-alpha-carbinolamine dehydratase
GWG10_09925	COG2885	chlorophyll binding
GWG10_09935	COG1570	exodeoxyribonuclease VII activity
GWG10_09945	COG1874	Beta-galactosidase
GWG10_09945	COG0366	Alpha amylase catalytic
GWG10_09955	COG0516	GMP reductase activity
GWG10_09955	COG0517	IMP dehydrogenase activity
GWG10_09960	COG0519	Catalyzes the synthesis of GMP from XMP
GWG10_09960	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GWG10_09970	COG3039	Transposase
GWG10_09995	COG1846	Transcriptional regulator
GWG10_10010	COG0500	methyltransferase
GWG10_10020	COG2062	phosphohistidine phosphatase, SixA
GWG10_10030	COG0697	spore germination
GWG10_10045	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GWG10_10050	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GWG10_10060	COG4591	ABC-type transport system involved in lipoprotein release permease component
GWG10_10065	COG1136	(ABC) transporter
GWG10_10070	COG4591	ABC-type transport system involved in lipoprotein release permease component
GWG10_10075	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GWG10_10085	COG0544	peptidyl-prolyl cis-trans isomerase activity
GWG10_10090	COG0740	serine-type endopeptidase activity
GWG10_10095	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GWG10_10100	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GWG10_10105	COG0776	regulation of translation
GWG10_10110	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GWG10_10115	COG0488	(ABC) transporter
GWG10_10120	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GWG10_10125	COG3162	membrane
GWG10_10140	COG1024	Enoyl-CoA hydratase
GWG10_10145	COG1115	amino acid carrier protein
GWG10_10155	COG3228	Belongs to the MtfA family
GWG10_10160	COG1584	GPR1 FUN34 yaaH family protein
GWG10_10185	COG1024	Enoyl-CoA hydratase
GWG10_10190	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GWG10_10195	COG1960	acyl-CoA dehydrogenase activity
GWG10_10205	COG1960	acyl-CoA dehydrogenase activity
GWG10_10210	COG1024	Enoyl-CoA hydratase
GWG10_10215	COG1024	Enoyl-CoA hydratase
GWG10_10225	COG1028	Short-chain dehydrogenase reductase Sdr
GWG10_10235	COG0730	response to heat
GWG10_10270	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GWG10_10275	COG3328	transposase activity
GWG10_10285	COG3039	Transposase
GWG10_10315	COG1172	Belongs to the binding-protein-dependent transport system permease family
GWG10_10320	COG1172	Belongs to the binding-protein-dependent transport system permease family
GWG10_10325	COG1129	ABC transporter
GWG10_10330	COG1879	ABC-type sugar transport system periplasmic component
GWG10_10335	COG0583	DNA-binding transcription factor activity
GWG10_10350	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GWG10_10355	COG0243	molybdopterin cofactor binding
GWG10_10365	COG0583	DNA-binding transcription factor activity
GWG10_10370	COG2723	6-phospho-beta-galactosidase activity
GWG10_10380	COG0583	DNA-binding transcription factor activity
GWG10_10395	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GWG10_10400	COG0673	inositol 2-dehydrogenase activity
GWG10_10405	COG0583	DNA-binding transcription factor activity
GWG10_10415	COG1560	Kdo2-lipid A biosynthetic process
GWG10_10420	COG1560	Kdo2-lipid A biosynthetic process
GWG10_10435	COG0417	DNA replication proofreading
GWG10_10465	COG0534	Mate efflux family protein
GWG10_10475	COG0307	riboflavin synthase, alpha
GWG10_10490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GWG10_10495	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GWG10_10500	COG0697	spore germination
GWG10_10505	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GWG10_10535	COG0675	Transposase, IS605 OrfB family
GWG10_10540	COG2996	Protein conserved in bacteria
GWG10_10555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GWG10_10560	COG3099	Belongs to the UPF0263 family
GWG10_10565	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GWG10_10570	COG2894	cell division
GWG10_10575	COG0850	regulation of cytokinetic process
GWG10_10580	COG3100	YcgL domain-containing protein
GWG10_10585	COG2951	lytic endotransglycosylase activity
GWG10_10590	COG1760	l-serine dehydratase
GWG10_10595	COG1760	l-serine dehydratase
GWG10_10600	COG3123	guanosine phosphorylase activity
GWG10_10605	COG1301	dicarboxylic acid transport
GWG10_10620	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GWG10_10625	COG2067	long-chain fatty acid transport protein
GWG10_10630	COG2067	long-chain fatty acid transport protein
GWG10_10640	COG1595	DNA-templated transcription, initiation
GWG10_10670	COG0714	Associated with various cellular activities
GWG10_10675	COG0183	Belongs to the thiolase family
GWG10_10680	COG1024	Enoyl-CoA hydratase
GWG10_10680	COG1250	3-hydroxyacyl-CoA dehydrogenase
GWG10_10690	COG4681	YaeQ
GWG10_10710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GWG10_10725	COG3134	Outer membrane lipoprotein
GWG10_10730	COG0318	PFAM AMP-dependent synthetase and ligase
GWG10_10765	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GWG10_10765	COG0140	phosphoribosyl-ATP diphosphatase activity
GWG10_10770	COG0107	imidazoleglycerol-phosphate synthase activity
GWG10_10775	COG2205	protein histidine kinase activity
GWG10_10775	COG2198	Histidine kinase
GWG10_10775	COG0784	Response regulator, receiver
GWG10_10785	COG3437	response regulator, receiver
GWG10_10790	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GWG10_10795	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GWG10_10800	COG0131	Imidazoleglycerol-phosphate dehydratase
GWG10_10800	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GWG10_10805	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GWG10_10810	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GWG10_10815	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GWG10_10825	COG1199	ATP-dependent helicase activity
GWG10_10830	COG1214	PFAM Peptidase M22, glycoprotease
GWG10_10840	COG0596	Alpha beta hydrolase
GWG10_10845	COG0318	PFAM AMP-dependent synthetase and ligase
GWG10_10860	COG0697	spore germination
GWG10_10870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GWG10_10875	COG2832	Protein of unknown function (DUF454)
GWG10_10880	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GWG10_10890	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GWG10_10895	COG0583	DNA-binding transcription factor activity
GWG10_10910	COG2197	response regulator
GWG10_10915	COG0617	tRNA 3'-terminal CCA addition
GWG10_10915	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GWG10_10915	COG0517	IMP dehydrogenase activity
GWG10_10920	COG1643	Atp-dependent helicase
GWG10_10930	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GWG10_10945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GWG10_10950	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
GWG10_10955	COG0709	Synthesizes selenophosphate from selenide and ATP
GWG10_10970	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GWG10_10975	COG0840	transmembrane signaling receptor activity
GWG10_10980	COG1254	Belongs to the acylphosphatase family
GWG10_10990	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GWG10_10990	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GWG10_10995	COG0489	protein tyrosine kinase activity
GWG10_11000	COG0572	uridine kinase
GWG10_11005	COG0717	Belongs to the dCTP deaminase family
GWG10_11010	COG0306	phosphate transporter
GWG10_11015	COG1530	ribonuclease E activity
GWG10_11020	COG0564	pseudouridine synthase activity
GWG10_11035	COG1399	metal-binding, possibly nucleic acid-binding protein
GWG10_11040	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GWG10_11045	COG0416	fatty acid biosynthetic process
GWG10_11050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GWG10_11060	COG1028	Short-chain dehydrogenase reductase Sdr
GWG10_11065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GWG10_11070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GWG10_11075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GWG10_11080	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GWG10_11085	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GWG10_11090	COG0470	DNA polymerase III
GWG10_11095	COG0084	hydrolase, TatD family'
GWG10_11115	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GWG10_11115	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GWG10_11120	COG3008	intermembrane lipid transfer
GWG10_11125	COG2995	paraquat-inducible protein a
GWG10_11135	COG3141	response to X-ray
GWG10_11185	COG1074	ATP-dependent DNA helicase activity
GWG10_11190	COG3328	transposase activity
GWG10_11210	COG0583	DNA-binding transcription factor activity
GWG10_11235	COG0633	Ferredoxin
GWG10_11240	COG0789	Transcriptional regulator
GWG10_11250	COG0640	Transcriptional regulator
GWG10_11270	COG1937	Protein conserved in bacteria
GWG10_11275	COG1230	cation diffusion facilitator family transporter
GWG10_11280	COG0640	Transcriptional regulator
GWG10_11415	COG1067	ATP-dependent peptidase activity
GWG10_11420	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GWG10_11445	COG0116	Belongs to the methyltransferase superfamily
GWG10_11445	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GWG10_11455	COG0167	dihydroorotate dehydrogenase activity
GWG10_11460	COG2902	Dehydrogenase
GWG10_11470	COG0308	aminopeptidase N
GWG10_11480	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GWG10_11485	COG1956	GAF domain-containing protein
GWG10_11500	COG3278	Belongs to the heme-copper respiratory oxidase family
GWG10_11515	COG2010	Cytochrome c
GWG10_11525	COG2217	Heavy metal translocating P-type atpase
GWG10_11540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GWG10_11545	COG0589	response to stress
GWG10_11550	COG0037	tRNA processing
GWG10_11565	COG0625	glutathione transferase activity
GWG10_11570	COG1869	D-ribose catabolic process
GWG10_11575	COG1129	ABC transporter
GWG10_11580	COG1172	Belongs to the binding-protein-dependent transport system permease family
GWG10_11585	COG1879	ABC-type sugar transport system periplasmic component
GWG10_11590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GWG10_11595	COG1609	Transcriptional regulator
GWG10_11630	COG0776	regulation of translation
GWG10_11635	COG0072	phenylalanine-tRNA ligase activity
GWG10_11635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GWG10_11640	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GWG10_11645	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GWG10_11650	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GWG10_11655	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GWG10_11660	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GWG10_11695	COG0675	Transposase, IS605 OrfB family
GWG10_11715	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GWG10_11725	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GWG10_11730	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GWG10_11735	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GWG10_11740	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GWG10_11745	COG3313	Fe-S protein
GWG10_11750	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GWG10_11750	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWG10_11750	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWG10_11755	COG1105	Belongs to the carbohydrate kinase PfkB family
GWG10_11760	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWG10_11760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWG10_11765	COG1609	Transcriptional regulator
GWG10_11770	COG0814	amino acid
GWG10_11780	COG5654	RES domain protein
GWG10_11785	COG0513	Belongs to the DEAD box helicase family
GWG10_11795	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GWG10_11800	COG2890	protein-(glutamine-N5) methyltransferase activity
GWG10_11805	COG2840	Smr protein MutS2
GWG10_11840	COG2824	Alkylphosphonate utilization operon protein PhnA
GWG10_11855	COG1280	lysine exporter protein (LysE YggA)
GWG10_11915	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GWG10_11920	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GWG10_11930	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GWG10_11935	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GWG10_11945	COG0205	6-phosphofructokinase activity
GWG10_11955	COG1473	amidohydrolase
GWG10_11960	COG1011	Hydrolase
GWG10_11965	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GWG10_12010	COG3593	DNA synthesis involved in DNA repair
GWG10_12025	COG0583	DNA-binding transcription factor activity
GWG10_12030	COG0730	response to heat
GWG10_12040	COG1181	Belongs to the D-alanine--D-alanine ligase family
GWG10_12050	COG0386	Belongs to the glutathione peroxidase family
GWG10_12055	COG0513	Belongs to the DEAD box helicase family
GWG10_12090	COG2329	Antibiotic biosynthesis monooxygenase
GWG10_12095	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GWG10_12130	COG2501	S4 domain
GWG10_12150	COG3385	transposase activity
GWG10_12155	COG1132	(ABC) transporter
GWG10_12165	COG1132	(ABC) transporter
GWG10_12175	COG3118	belongs to the thioredoxin family
GWG10_12180	COG0471	metal ion transport
GWG10_12190	COG0058	SHG alpha-glucan phosphorylase activity
GWG10_12220	COG0814	amino acid
GWG10_12225	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GWG10_12230	COG0514	ATP-dependent DNA helicase (RecQ)
GWG10_12235	COG2766	serine protein kinase
GWG10_12240	COG2718	Belongs to the UPF0229 family
GWG10_12245	COG2719	SpoVR family
GWG10_12250	COG2186	Transcriptional regulator
GWG10_12255	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GWG10_12260	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GWG10_12265	COG0586	Pfam SNARE associated Golgi protein
GWG10_12275	COG0556	nucleotide-excision repair
GWG10_12285	COG0569	domain protein
GWG10_12285	COG2985	domain, Protein
GWG10_12290	COG0739	heme binding
GWG10_12290	COG0741	lytic transglycosylase activity
GWG10_12290	COG1196	nuclear chromosome segregation
GWG10_12295	COG3181	Tripartite tricarboxylate transporter family receptor
GWG10_12310	COG4565	transcriptional regulatory protein
GWG10_12315	COG3290	protein histidine kinase activity
GWG10_12320	COG1940	carbohydrate kinase activity
GWG10_12320	COG1846	Transcriptional regulator
GWG10_12325	COG0840	transmembrane signaling receptor activity
GWG10_12330	COG3012	SEC-C Motif Domain Protein
GWG10_12335	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GWG10_12340	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
GWG10_12350	COG0247	lactate metabolic process
GWG10_12370	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GWG10_12375	COG0437	4 iron, 4 sulfur cluster binding
GWG10_12380	COG3301	Polysulphide reductase, NrfD
GWG10_12390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GWG10_12395	COG3088	subunit of a heme lyase
GWG10_12395	COG4235	cytochrome complex assembly
GWG10_12410	COG3046	protein related to deoxyribodipyrimidine photolyase
GWG10_12415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GWG10_12430	COG0617	tRNA 3'-terminal CCA addition
GWG10_12430	COG0517	IMP dehydrogenase activity
GWG10_12430	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GWG10_12440	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GWG10_12445	COG0583	DNA-binding transcription factor activity
GWG10_12455	COG4774	siderophore transport
GWG10_12460	COG3706	GGDEF domain
GWG10_12465	COG2200	EAL domain
GWG10_12470	COG4977	sequence-specific DNA binding
GWG10_12470	COG1917	Cupin 2, conserved barrel domain protein
GWG10_12475	COG0583	DNA-binding transcription factor activity
GWG10_12480	COG2910	NAD(P)H-binding
GWG10_12490	COG0626	cystathionine gamma-synthase activity
GWG10_12495	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GWG10_12540	COG3039	Transposase
GWG10_12550	COG3250	beta-galactosidase activity
GWG10_12565	COG2223	nitrite transmembrane transporter activity
GWG10_12585	COG1609	Transcriptional regulator
GWG10_12590	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GWG10_12595	COG1085	galactose-1-phosphate uridylyltransferase
GWG10_12600	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GWG10_12605	COG0469	pyruvate kinase activity
GWG10_12680	COG0210	DNA helicase
GWG10_12685	COG1111	helicase
GWG10_12685	COG1205	dead DEAH box helicase
GWG10_12695	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GWG10_12705	COG3039	Transposase
GWG10_12790	COG3550	peptidyl-serine autophosphorylation
GWG10_12800	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GWG10_12815	COG2723	6-phospho-beta-galactosidase activity
GWG10_12830	COG1737	Transcriptional regulator
GWG10_12850	COG1435	thymidine kinase activity
GWG10_12855	COG1757	Na H antiporter
GWG10_12860	COG2916	Histone family protein nucleoid-structuring protein H-NS
GWG10_12865	COG2096	Adenosyltransferase
GWG10_12870	COG3530	Putative quorum-sensing-regulated virulence factor
GWG10_12875	COG0602	queuosine metabolic process
GWG10_12880	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GWG10_12900	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GWG10_12910	COG0776	regulation of translation
GWG10_12915	COG0539	negative regulation of cytoplasmic translation
GWG10_12920	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GWG10_12925	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GWG10_12955	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GWG10_12960	COG5001	Diguanylate cyclase
GWG10_12960	COG3300	MHYT domain
GWG10_12970	COG0583	DNA-binding transcription factor activity
GWG10_12975	COG0745	RESPONSE REGULATOR receiver
GWG10_13000	COG4989	oxidoreductase activity
GWG10_13005	COG0724	RNA recognition motif
GWG10_13015	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
GWG10_13025	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GWG10_13045	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GWG10_13050	COG1360	Flagellar Motor Protein
GWG10_13055	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GWG10_13060	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GWG10_13065	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GWG10_13065	COG0649	NAD binding
GWG10_13080	COG1034	ATP synthesis coupled electron transport
GWG10_13085	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GWG10_13090	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GWG10_13095	COG0839	Belongs to the complex I subunit 6 family
GWG10_13100	COG0713	ATP synthesis coupled electron transport
GWG10_13110	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GWG10_13115	COG1007	ATP synthesis coupled electron transport
GWG10_13120	COG0047	phosphoribosylformylglycinamidine synthase activity
GWG10_13120	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GWG10_13125	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GWG10_13135	COG1645	bacterial-type flagellum-dependent swarming motility
GWG10_13140	COG1160	GTP binding
GWG10_13145	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GWG10_13150	COG2976	Protein conserved in bacteria
GWG10_13155	COG0124	histidyl-tRNA synthetase
GWG10_13165	COG1426	Protein conserved in bacteria
GWG10_13175	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GWG10_13180	COG0105	UTP biosynthetic process
GWG10_13185	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GWG10_13195	COG0633	Ferredoxin
GWG10_13200	COG0443	Heat shock 70 kDa protein
GWG10_13205	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GWG10_13215	COG0822	iron-sulfur transferase activity
GWG10_13220	COG1104	cysteine desulfurase activity
GWG10_13235	COG3154	lipid carrier protein
GWG10_13240	COG0826	peptidase U32
GWG10_13245	COG0826	peptidase U32
GWG10_13255	COG2897	thiosulfate sulfurtransferase activity
GWG10_13260	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GWG10_13265	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GWG10_13270	COG1862	Preprotein translocase
GWG10_13275	COG0343	queuine tRNA-ribosyltransferase activity
GWG10_13280	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GWG10_13285	COG0517	IMP dehydrogenase activity
GWG10_13290	COG0450	alkyl hydroperoxide reductase
GWG10_13295	COG3634	alkyl hydroperoxide reductase activity
GWG10_13320	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GWG10_13320	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GWG10_13325	COG0509	glycine decarboxylation via glycine cleavage system
GWG10_13330	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GWG10_13335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GWG10_13340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GWG10_13360	COG2814	Major facilitator Superfamily
GWG10_13365	COG0444	Belongs to the ABC transporter superfamily
GWG10_13370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GWG10_13375	COG0601	transmembrane transport
GWG10_13385	COG0625	glutathione transferase activity
GWG10_13390	COG0625	glutathione transferase activity
GWG10_13400	COG0483	inositol monophosphate 1-phosphatase activity
GWG10_13415	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GWG10_13420	COG2056	Na+-H+ antiporter family
GWG10_13425	COG2814	Major facilitator Superfamily
GWG10_13430	COG0583	DNA-binding transcription factor activity
GWG10_13435	COG5001	Diguanylate cyclase
GWG10_13450	COG2050	protein possibly involved in aromatic compounds catabolism
GWG10_13460	COG0247	lactate metabolic process
GWG10_13460	COG0277	FAD linked oxidase domain protein
GWG10_13475	COG1253	flavin adenine dinucleotide binding
GWG10_13480	COG1902	pentaerythritol trinitrate reductase activity
GWG10_13490	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GWG10_13495	COG0647	UMP catabolic process
GWG10_13505	COG0367	asparagine synthase
GWG10_13520	COG0625	glutathione transferase activity
GWG10_13530	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GWG10_13545	COG0564	pseudouridine synthase activity
GWG10_13550	COG5001	Diguanylate cyclase
GWG10_13560	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GWG10_13595	COG0670	Belongs to the BI1 family
GWG10_13600	COG1289	transmembrane transporter activity
GWG10_13605	COG2920	part of a sulfur-relay system
GWG10_13610	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GWG10_13615	COG0285	dihydrofolate synthase activity
GWG10_13620	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GWG10_13625	COG0101	tRNA pseudouridine synthase activity
GWG10_13635	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GWG10_13640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GWG10_13650	COG1464	Belongs to the NlpA lipoprotein family
GWG10_13670	COG1119	ATPase activity
GWG10_13675	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GWG10_13675	COG0574	Belongs to the PEP-utilizing enzyme family
GWG10_13680	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GWG10_13690	COG1113	amino acid transport
GWG10_13735	COG1242	4 iron, 4 sulfur cluster binding
GWG10_13740	COG0069	glutamate synthase activity
GWG10_13740	COG0070	glutamate synthase
GWG10_13740	COG0067	glutamate synthase
GWG10_13745	COG0493	'glutamate synthase
GWG10_13760	COG4104	PAAR repeat-containing protein
GWG10_13770	COG0513	Belongs to the DEAD box helicase family
GWG10_13800	COG3706	GGDEF domain
GWG10_13805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GWG10_13810	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GWG10_13815	COG0505	Belongs to the CarA family
GWG10_13820	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GWG10_13830	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GWG10_13835	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GWG10_13840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GWG10_13845	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GWG10_13850	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GWG10_13855	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
GWG10_13860	COG4139	cobalamin transport
GWG10_13885	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GWG10_13895	COG0023	Translation Initiation Factor
GWG10_13900	COG2119	membrane
GWG10_13935	COG2203	Gaf domain
GWG10_13935	COG2199	diguanylate cyclase activity
GWG10_13940	COG0556	nucleotide-excision repair
GWG10_13965	COG0215	cysteine-tRNA ligase activity
GWG10_13970	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GWG10_13980	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GWG10_13985	COG2261	transglycosylase associated protein
GWG10_13990	COG1309	transcriptional regulator
GWG10_13995	COG0604	alcohol dehydrogenase
GWG10_14025	COG0322	excinuclease ABC activity
GWG10_14030	COG2197	response regulator
GWG10_14035	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GWG10_14040	COG2835	tetraacyldisaccharide 4'-kinase activity
GWG10_14045	COG1663	tetraacyldisaccharide 4'-kinase activity
GWG10_14050	COG1132	(ABC) transporter
GWG10_14055	COG2333	competence protein COMEC
GWG10_14055	COG0658	competence protein
GWG10_14070	COG0433	COG0433 Predicted ATPase
GWG10_14075	COG1448	Aminotransferase
GWG10_14090	COG1199	ATP-dependent helicase activity
GWG10_14105	COG0123	including yeast histone deacetylase and acetoin utilization protein
GWG10_14110	COG0477	Major facilitator Superfamily
GWG10_14115	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GWG10_14120	COG1785	Belongs to the alkaline phosphatase family
GWG10_14140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GWG10_14145	COG3706	GGDEF domain
GWG10_14150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GWG10_14155	COG0765	amino acid transport
GWG10_14160	COG1126	abc transporter atp-binding protein
GWG10_14170	COG0531	amino acid
GWG10_14185	COG1253	flavin adenine dinucleotide binding
GWG10_14190	COG0704	Plays a role in the regulation of phosphate uptake
GWG10_14200	COG0581	inorganic phosphate transmembrane transporter activity
GWG10_14205	COG0573	inorganic phosphate transmembrane transporter activity
GWG10_14210	COG0590	tRNA wobble adenosine to inosine editing
GWG10_14220	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GWG10_14240	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GWG10_14245	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GWG10_14250	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GWG10_14255	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GWG10_14265	COG3852	Histidine kinase
GWG10_14280	COG2716	regulation of RNA biosynthetic process
GWG10_14285	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GWG10_14295	COG2239	Acts as a magnesium transporter
GWG10_14310	COG3951	Flagellar rod assembly protein muramidase FlgJ
GWG10_14310	COG1705	Flagellar rod assembly protein muramidase FlgJ
GWG10_14315	COG1706	bacterial-type flagellum-dependent cell motility
GWG10_14320	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GWG10_14335	COG1749	Flagellar hook protein flgE
GWG10_14350	COG1815	bacterial-type flagellum-dependent cell motility
GWG10_14355	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GWG10_14360	COG0835	chemotaxis
GWG10_14360	COG0784	Response regulator, receiver
GWG10_14365	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
GWG10_14380	COG0622	Phosphoesterase
GWG10_14385	COG4166	transmembrane transport
GWG10_14400	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GWG10_14405	COG0675	Transposase, IS605 OrfB family
GWG10_14415	COG0697	spore germination
GWG10_14420	COG4166	transmembrane transport
GWG10_14445	COG1278	Cold shock
GWG10_14485	COG0675	Transposase, IS605 OrfB family
GWG10_14495	COG3132	Protein of unknown function, DUF480
GWG10_14515	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GWG10_14535	COG3206	protein involved in exopolysaccharide biosynthesis
GWG10_14535	COG0489	protein tyrosine kinase activity
GWG10_14540	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GWG10_14580	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GWG10_14630	COG1091	dTDP-4-dehydrorhamnose reductase activity
GWG10_14640	COG0745	RESPONSE REGULATOR receiver
GWG10_14655	COG1737	Transcriptional regulator
GWG10_14660	COG0469	pyruvate kinase activity
GWG10_14670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GWG10_14675	COG1960	acyl-CoA dehydrogenase activity
GWG10_14685	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GWG10_14705	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GWG10_14710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GWG10_14715	COG1309	transcriptional regulator
GWG10_14730	COG1946	Acyl-CoA thioesterase
GWG10_14745	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GWG10_14755	COG0009	L-threonylcarbamoyladenylate synthase
GWG10_14760	COG0613	PHP domain protein
GWG10_14765	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GWG10_14770	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GWG10_14770	COG0512	Glutamine amidotransferase of anthranilate synthase
GWG10_14775	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GWG10_14780	COG0135	phosphoribosylanthranilate isomerase activity
GWG10_14780	COG0134	indole-3-glycerol-phosphate synthase activity
GWG10_14785	COG0133	tryptophan synthase activity
GWG10_14790	COG0159	tryptophan synthase activity
GWG10_14825	COG1988	membrane-bound metal-dependent
GWG10_14830	COG1396	sequence-specific DNA binding
GWG10_14835	COG3550	peptidyl-serine autophosphorylation
GWG10_14855	COG0583	DNA-binding transcription factor activity
GWG10_14865	COG5507	3-demethylubiquinone-9 3-methyltransferase
GWG10_14870	COG2814	Major facilitator Superfamily
GWG10_14880	COG0109	protoheme IX farnesyltransferase activity
GWG10_14885	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GWG10_14890	COG1845	cytochrome c oxidase, subunit III
GWG10_14895	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GWG10_14900	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GWG10_14905	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GWG10_14910	COG0583	DNA-binding transcription factor activity
GWG10_14930	COG1846	Transcriptional regulator
GWG10_14945	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
GWG10_14960	COG0745	RESPONSE REGULATOR receiver
GWG10_14970	COG0708	Exodeoxyribonuclease III
GWG10_14980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GWG10_14985	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GWG10_15000	COG0095	Lipoate-protein ligase
GWG10_15020	COG2391	methyltransferase activity
GWG10_15030	COG0640	Transcriptional regulator
GWG10_15040	COG0446	pyridine nucleotide-disulphide oxidoreductase
GWG10_15050	COG1285	pathogenesis
GWG10_15080	COG0484	heat shock protein binding
GWG10_15085	COG0443	Heat shock 70 kDa protein
GWG10_15090	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GWG10_15095	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GWG10_15100	COG3706	GGDEF domain
GWG10_15105	COG0497	DNA recombination
GWG10_15115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GWG10_15120	COG0577	efflux transmembrane transporter activity
GWG10_15120	COG1136	(ABC) transporter
GWG10_15130	COG2375	cellular response to nickel ion
GWG10_15135	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GWG10_15140	COG2916	Histone family protein nucleoid-structuring protein H-NS
GWG10_15145	COG0583	DNA-binding transcription factor activity
GWG10_15150	COG3048	D-serine ammonia-lyase activity
GWG10_15160	COG0538	isocitrate dehydrogenase activity
GWG10_15190	COG0456	acetyltransferase
GWG10_15195	COG1187	pseudouridine synthase activity
GWG10_15205	COG0482	sulfurtransferase activity
GWG10_15210	COG2915	High frequency lysogenization protein hflD homolog
GWG10_15215	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GWG10_15220	COG2850	peptidyl-arginine hydroxylation
GWG10_15230	COG1196	nuclear chromosome segregation
GWG10_15230	COG3264	Mechanosensitive ion channel
GWG10_15260	COG0281	malic enzyme
GWG10_15265	COG0746	molybdenum cofactor guanylyltransferase activity
GWG10_15270	COG1763	Mo-molybdopterin cofactor biosynthetic process
GWG10_15275	COG1289	transmembrane transporter activity
GWG10_15280	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GWG10_15310	COG3220	belongs to the UPF0276 family
GWG10_15320	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GWG10_15350	COG4319	ketosteroid isomerase
GWG10_15355	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GWG10_15360	COG0083	homoserine kinase activity
GWG10_15375	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GWG10_15380	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
GWG10_15395	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GWG10_15405	COG0745	RESPONSE REGULATOR receiver
GWG10_15420	COG4988	ABC transporter
GWG10_15425	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GWG10_15445	COG1720	tRNA m6t6A37 methyltransferase activity
GWG10_15460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GWG10_15465	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GWG10_15475	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWG10_15485	COG2190	(PTS) system
GWG10_15490	COG3038	cytochrome b561
GWG10_15500	COG0420	3'-5' exonuclease activity
GWG10_15505	COG1247	-acetyltransferase
GWG10_15510	COG2974	May be involved in recombination
GWG10_15525	COG5433	transposase activity
GWG10_15535	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GWG10_15535	COG4651	solute:proton antiporter activity
GWG10_15570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GWG10_15575	COG1396	sequence-specific DNA binding
GWG10_15575	COG1917	Cupin 2, conserved barrel domain protein
GWG10_15580	COG1012	belongs to the aldehyde dehydrogenase family
GWG10_15590	COG0531	amino acid
GWG10_15595	COG0531	amino acid
GWG10_15605	COG1283	sodium-dependent phosphate transmembrane transporter activity
GWG10_15615	COG3384	dioxygenase
GWG10_15620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GWG10_15620	COG2205	protein histidine kinase activity
GWG10_15645	COG2205	protein histidine kinase activity
GWG10_15645	COG0784	Response regulator, receiver
GWG10_15655	COG1376	ErfK ybiS ycfS ynhG family protein
GWG10_15655	COG1388	LysM domain
GWG10_15670	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
GWG10_15675	COG0791	NLP P60 protein
GWG10_15685	COG3118	belongs to the thioredoxin family
GWG10_15695	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GWG10_15700	COG0788	formyltetrahydrofolate deformylase activity
GWG10_15725	COG1196	nuclear chromosome segregation
GWG10_15725	COG0739	heme binding
GWG10_15725	COG0741	lytic transglycosylase activity
GWG10_15735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GWG10_15740	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GWG10_15745	COG0673	inositol 2-dehydrogenase activity
GWG10_15775	COG1032	radical SAM domain protein
GWG10_15780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GWG10_15790	COG3706	GGDEF domain
GWG10_15795	COG1752	Esterase of the alpha-beta hydrolase superfamily
GWG10_15800	COG0733	neurotransmitter:sodium symporter activity
GWG10_15830	COG0281	malic enzyme
GWG10_15835	COG2207	Transcriptional regulator
GWG10_15855	COG2233	PERMEase
GWG10_15860	COG0095	Lipoate-protein ligase
GWG10_15865	COG1115	amino acid carrier protein
GWG10_15870	COG0019	diaminopimelate decarboxylase activity
GWG10_15880	COG0678	peroxiredoxin activity
GWG10_15885	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GWG10_15895	COG1126	abc transporter atp-binding protein
GWG10_15900	COG0765	amino acid transport
GWG10_15905	COG4597	amino acid ABC transporter
GWG10_15910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GWG10_15925	COG1131	(ABC) transporter
GWG10_15930	COG0545	Peptidyl-prolyl cis-trans isomerase
GWG10_15950	COG3142	Participates in the control of copper homeostasis
GWG10_15955	COG1940	carbohydrate kinase activity
GWG10_15965	COG4783	chaperone-mediated protein folding
GWG10_15975	COG5002	protein histidine kinase activity
GWG10_15980	COG0745	RESPONSE REGULATOR receiver
GWG10_15985	COG0346	lactoylglutathione lyase activity
GWG10_15990	COG3706	GGDEF domain
GWG10_15995	COG3284	Transcriptional regulator
GWG10_16000	COG1012	belongs to the aldehyde dehydrogenase family
GWG10_16010	COG0697	spore germination
GWG10_16020	COG0667	Aldo Keto reductase
GWG10_16035	COG3290	protein histidine kinase activity
GWG10_16045	COG1566	PFAM secretion protein HlyD family protein
GWG10_16070	COG0602	queuosine metabolic process
GWG10_16075	COG1328	CTP reductase activity
GWG10_16085	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GWG10_16090	COG3115	cell septum assembly
GWG10_16095	COG1196	nuclear chromosome segregation
GWG10_16105	COG2860	membrane
GWG10_16115	COG3108	Peptidase M15
GWG10_16120	COG2989	Protein conserved in bacteria
GWG10_16135	COG0463	Glycosyl transferase, family 2
GWG10_16195	COG3706	GGDEF domain
GWG10_16200	COG0037	tRNA processing
GWG10_16215	COG0488	(ABC) transporter
GWG10_16225	COG0531	amino acid
GWG10_16230	COG0814	amino acid
GWG10_16245	COG0825	malonyl-CoA metabolic process
GWG10_16250	COG0587	DNA-directed DNA polymerase activity
GWG10_16255	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GWG10_16260	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GWG10_16265	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GWG10_16270	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GWG10_16275	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GWG10_16290	COG0750	zinc metalloprotease
GWG10_16295	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GWG10_16300	COG0575	Belongs to the CDS family
GWG10_16305	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GWG10_16310	COG0233	cytoplasmic translational termination
GWG10_16315	COG0528	UMP kinase activity
GWG10_16320	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GWG10_16325	COG0052	Belongs to the universal ribosomal protein uS2 family
GWG10_16330	COG0024	Methionine aminopeptidase
GWG10_16335	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GWG10_16340	COG2171	N-acyltransferase activity
GWG10_16350	COG1263	PTS System
GWG10_16350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWG10_16375	COG0564	pseudouridine synthase activity
GWG10_16380	COG3098	single-species biofilm formation
GWG10_16405	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
GWG10_16415	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GWG10_16415	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GWG10_16425	COG3706	GGDEF domain
GWG10_16430	COG1611	Belongs to the LOG family
GWG10_16435	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GWG10_16440	COG0473	3-isopropylmalate dehydrogenase activity
GWG10_16450	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
GWG10_16465	COG0583	DNA-binding transcription factor activity
GWG10_16470	COG0840	transmembrane signaling receptor activity
GWG10_16475	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GWG10_16490	COG1477	protein flavinylation
GWG10_16495	COG2871	sodium ion transport
GWG10_16500	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GWG10_16505	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GWG10_16510	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GWG10_16515	COG1805	sodium ion transport
GWG10_16520	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GWG10_16525	COG0271	Belongs to the BolA IbaG family
GWG10_16530	COG2813	Specifically methylates the guanine in position
GWG10_16540	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GWG10_16550	COG2211	Major facilitator Superfamily
GWG10_16555	COG3248	Nucleoside-binding outer membrane protein
GWG10_16560	COG1666	GTP binding
GWG10_16575	COG0659	secondary active sulfate transmembrane transporter activity
GWG10_16585	COG0745	RESPONSE REGULATOR receiver
GWG10_16590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GWG10_16595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GWG10_16605	COG0582	viral genome integration into host DNA
GWG10_16615	COG2916	Histone family protein nucleoid-structuring protein H-NS
GWG10_16625	COG4983	Phage plasmid primase, P4 family domain protein
GWG10_16645	COG5377	YqaJ viral recombinase family
GWG10_16680	COG2003	Belongs to the UPF0758 family
GWG10_16735	COG0583	DNA-binding transcription factor activity
GWG10_16740	COG0549	Belongs to the carbamate kinase family
GWG10_16745	COG1304	FMN binding
GWG10_16750	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GWG10_16795	COG2003	Belongs to the UPF0758 family
GWG10_16820	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GWG10_16845	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GWG10_16855	COG3012	SEC-C Motif Domain Protein
GWG10_16855	COG3318	Belongs to the UPF0149 family
GWG10_16870	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GWG10_16880	COG1151	hydroxylamine reductase activity
GWG10_16885	COG0783	Belongs to the Dps family
GWG10_16910	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GWG10_16925	COG4221	oxidoreductase activity
GWG10_16935	COG0415	Belongs to the DNA photolyase family
GWG10_16940	COG0789	Transcriptional regulator
GWG10_16945	COG3272	Protein of unknown function (DUF1722)
GWG10_16970	COG0077	Prephenate dehydratase
GWG10_16970	COG1605	Chorismate mutase
GWG10_17045	COG2801	Transposase and inactivated derivatives
GWG10_17055	COG2199	diguanylate cyclase activity
GWG10_17055	COG2203	Gaf domain
GWG10_17075	COG5642	Protein of unknown function (DUF2384)
GWG10_17095	COG3328	transposase activity
GWG10_17110	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GWG10_17135	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GWG10_17175	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GWG10_17180	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GWG10_17245	COG4584	PFAM Integrase catalytic
GWG10_17270	COG2916	Histone family protein nucleoid-structuring protein H-NS
GWG10_17275	COG3039	Transposase
GWG10_17320	COG1484	DNA-dependent DNA replication
GWG10_17325	COG4584	PFAM Integrase catalytic
GWG10_17340	COG2133	pyrroloquinoline quinone binding
GWG10_17350	COG1349	DNA-binding transcription factor activity
GWG10_17355	COG2084	Dehydrogenase
GWG10_17360	COG3395	kinase activity
GWG10_17365	COG0235	Class ii aldolase
GWG10_17370	COG3622	Belongs to the hyi family
GWG10_17375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GWG10_17380	COG2610	gluconate transmembrane transporter activity
GWG10_17400	COG0300	oxidoreductase activity
GWG10_17425	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GWG10_17445	COG3813	Protein conserved in bacteria
GWG10_17455	COG0826	peptidase U32
GWG10_17460	COG1280	lysine exporter protein (LysE YggA)
GWG10_17495	COG2203	Gaf domain
GWG10_17495	COG2199	diguanylate cyclase activity
GWG10_17495	COG2200	EAL domain
GWG10_17540	COG1566	PFAM secretion protein HlyD family protein
GWG10_17550	COG0114	fumarate hydratase activity
GWG10_17560	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GWG10_17560	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GWG10_17560	COG0506	proline dehydrogenase activity
GWG10_17565	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GWG10_17580	COG0737	Belongs to the 5'-nucleotidase family
GWG10_17600	COG2204	response regulator
GWG10_17605	COG0545	Peptidyl-prolyl cis-trans isomerase
GWG10_17615	COG2900	Belongs to the SlyX family
GWG10_17620	COG1047	Peptidyl-prolyl cis-trans
GWG10_17625	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GWG10_17635	COG0835	chemotaxis
GWG10_17635	COG0784	Response regulator, receiver
GWG10_17640	COG0429	hydrolase of the alpha beta-hydrolase fold
GWG10_17645	COG5001	Diguanylate cyclase
GWG10_17645	COG2203	Gaf domain
GWG10_17645	COG3706	GGDEF domain
GWG10_17645	COG4251	negative regulation of phosphorylation
GWG10_17650	COG3089	Belongs to the UPF0270 family
GWG10_17655	COG3954	Phosphoribulokinase
GWG10_17670	COG1765	OsmC-like protein
GWG10_17680	COG2226	methyltransferase
GWG10_17690	COG2205	protein histidine kinase activity
GWG10_17690	COG2202	Pas domain
GWG10_17695	COG2814	Major facilitator Superfamily
GWG10_17720	COG0748	coenzyme F420 binding
GWG10_17725	COG3721	Heme iron utilization protein
GWG10_17735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GWG10_17760	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GWG10_17770	COG0463	Glycosyl transferase, family 2
GWG10_17775	COG0741	lytic transglycosylase activity
GWG10_17860	COG0616	signal peptide processing
GWG10_17875	COG4626	Terminase
GWG10_17875	COG1802	Transcriptional regulator
GWG10_17940	COG3328	transposase activity
GWG10_17950	COG4968	Prepilin-type N-terminal cleavage methylation domain
GWG10_17955	COG2135	peptidase activity
GWG10_17960	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GWG10_17965	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GWG10_17985	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GWG10_18060	COG1846	Transcriptional regulator
GWG10_18120	COG0582	viral genome integration into host DNA
GWG10_18125	COG0488	(ABC) transporter
GWG10_18135	COG2252	PERMEase
GWG10_18140	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GWG10_18145	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GWG10_18150	COG3178	'Phosphotransferase
GWG10_18155	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GWG10_18170	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GWG10_18175	COG2967	ApaG domain
GWG10_18180	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GWG10_18190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GWG10_18195	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GWG10_18205	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GWG10_18210	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GWG10_18215	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GWG10_18220	COG0142	geranyltranstransferase activity
GWG10_18225	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GWG10_18230	COG0330	HflC and HflK could
GWG10_18235	COG0330	HflC and HflK could
GWG10_18240	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GWG10_18245	COG1923	regulation of RNA biosynthetic process
GWG10_18250	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GWG10_18255	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GWG10_18265	COG0802	atpase or kinase
GWG10_18270	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GWG10_18270	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GWG10_18290	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GWG10_18295	COG2011	ABC-type metal ion transport system permease component
GWG10_18300	COG1464	Belongs to the NlpA lipoprotein family
GWG10_18320	COG0784	Response regulator, receiver
GWG10_18320	COG2205	protein histidine kinase activity
GWG10_18335	COG2198	Histidine kinase
GWG10_18335	COG5002	protein histidine kinase activity
GWG10_18335	COG0784	Response regulator, receiver
GWG10_18355	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GWG10_18370	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GWG10_18375	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GWG10_18380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GWG10_18385	COG2716	regulation of RNA biosynthetic process
GWG10_18390	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GWG10_18395	COG3013	Belongs to the UPF0304 family
GWG10_18405	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GWG10_18410	COG0280	phosphate acetyltransferase
GWG10_18410	COG0857	belongs to the CobB CobQ family
GWG10_18415	COG0440	acetolactate synthase activity
GWG10_18420	COG0028	Belongs to the TPP enzyme family
GWG10_18435	COG0671	phosphoesterase, PA-phosphatase related
GWG10_18445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GWG10_18450	COG0473	3-isopropylmalate dehydrogenase activity
GWG10_18455	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GWG10_18460	COG0066	3-isopropylmalate dehydratase activity
GWG10_18475	COG4143	(ABC) transporter
GWG10_18480	COG1178	ABC-type Fe3 transport system permease component
GWG10_18485	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GWG10_18490	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GWG10_18500	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GWG10_18535	COG0316	Belongs to the HesB IscA family
GWG10_18545	COG0038	chloride channel
GWG10_18550	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GWG10_18565	COG0671	phosphoesterase, PA-phosphatase related
GWG10_18575	COG0583	DNA-binding transcription factor activity
GWG10_18580	COG2076	Multidrug Resistance protein
GWG10_18590	COG0346	lactoylglutathione lyase activity
GWG10_18595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GWG10_18600	COG1643	Atp-dependent helicase
GWG10_18610	COG1489	DNA binding
GWG10_18615	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GWG10_18620	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GWG10_18630	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GWG10_18635	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GWG10_18640	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GWG10_18650	COG0842	Transport permease protein
GWG10_18655	COG1131	(ABC) transporter
GWG10_18670	COG0163	prenyltransferase activity
GWG10_18675	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GWG10_18680	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GWG10_18695	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GWG10_18710	COG1136	(ABC) transporter
GWG10_18770	COG2801	Transposase and inactivated derivatives
GWG10_18775	COG0529	Catalyzes the synthesis of activated sulfate
GWG10_18780	COG3273	potassium ion transport
GWG10_18780	COG0471	metal ion transport
GWG10_18785	COG2895	sulfate adenylyltransferase (ATP) activity
GWG10_18790	COG0175	sulfate reduction
GWG10_18795	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GWG10_18795	COG1648	precorrin-2 dehydrogenase activity
GWG10_18800	COG0330	HflC and HflK could
GWG10_18805	COG1585	Membrane protein implicated in regulation of membrane protease activity
GWG10_18815	COG0673	inositol 2-dehydrogenase activity
GWG10_18825	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GWG10_18830	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GWG10_18835	COG3036	rescue of stalled ribosome
GWG10_18850	COG0138	bifunctional purine biosynthesis protein purh
GWG10_18885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GWG10_18890	COG0358	DNA primase activity
GWG10_18895	COG1610	YqeY-like protein
GWG10_18900	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GWG10_18905	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GWG10_18915	COG4942	peptidase
GWG10_18915	COG1388	LysM domain
GWG10_18920	COG1238	metal cluster binding
GWG10_18925	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GWG10_18930	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GWG10_18935	COG0585	pseudouridine synthase activity
GWG10_18945	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GWG10_18950	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GWG10_18955	COG0148	phosphopyruvate hydratase activity
GWG10_18960	COG0504	CTP synthase activity
GWG10_18965	COG3956	TIGRFAM MazG family protein
GWG10_18970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GWG10_18975	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GWG10_18985	COG4807	Protein conserved in bacteria
GWG10_18990	COG3023	N-Acetylmuramoyl-L-alanine amidase
GWG10_18995	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GWG10_19000	COG1381	Involved in DNA repair and RecF pathway recombination
GWG10_19010	COG0571	ribonuclease III activity
GWG10_19015	COG0681	Belongs to the peptidase S26 family
GWG10_19020	COG0481	GTPase activity
GWG10_19035	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
GWG10_19040	COG1595	DNA-templated transcription, initiation
GWG10_19045	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GWG10_19055	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GWG10_19065	COG0583	DNA-binding transcription factor activity
GWG10_19095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GWG10_19105	COG0126	phosphoglycerate kinase activity
GWG10_19110	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GWG10_19115	COG1940	carbohydrate kinase activity
GWG10_19120	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GWG10_19125	COG2816	NAD+ diphosphatase activity
GWG10_19130	COG4991	sh3 domain protein
GWG10_19135	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GWG10_19150	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GWG10_19155	COG1028	Short-chain dehydrogenase reductase Sdr
GWG10_19165	COG1505	serine-type exopeptidase activity
GWG10_19170	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GWG10_19175	COG0765	amino acid transport
GWG10_19180	COG0765	amino acid transport
GWG10_19185	COG1126	abc transporter atp-binding protein
GWG10_19190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GWG10_19195	COG3174	membrane
GWG10_19200	COG0110	maltose O-acetyltransferase activity
GWG10_19230	COG1942	4-Oxalocrotonate Tautomerase
GWG10_19240	COG0583	DNA-binding transcription factor activity
GWG10_19250	COG0165	Argininosuccinate lyase
GWG10_19255	COG0137	argininosuccinate synthase activity
GWG10_19265	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GWG10_19270	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GWG10_19280	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GWG10_19285	COG3447	MASE1 domain protein
GWG10_19285	COG5001	Diguanylate cyclase
GWG10_19285	COG5002	protein histidine kinase activity
GWG10_19290	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GWG10_19325	COG0583	DNA-binding transcription factor activity
GWG10_19330	COG1380	Effector of murein hydrolase LrgA
GWG10_19335	COG1346	cytolysis
GWG10_19340	COG0460	homoserine dehydrogenase
GWG10_19340	COG0527	aspartate kinase activity
GWG10_19345	COG0626	cystathionine gamma-synthase activity
GWG10_19360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GWG10_19365	COG0814	amino acid
GWG10_19370	COG1218	3'(2'),5'-bisphosphate nucleotidase
GWG10_19375	COG0494	nUDIX hydrolase
GWG10_19380	COG1011	Hydrolase
GWG10_19385	COG1902	pentaerythritol trinitrate reductase activity
GWG10_19395	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GWG10_19410	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GWG10_19420	COG3156	type II secretion system protein K
GWG10_19430	COG4795	General secretion pathway protein
GWG10_19435	COG2165	general secretion pathway protein
GWG10_19445	COG2165	general secretion pathway protein
GWG10_19450	COG1459	type II secretion system
GWG10_19455	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GWG10_19465	COG3031	protein transport across the cell outer membrane
GWG10_19475	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GWG10_19480	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GWG10_19500	COG3133	Outer membrane lipoprotein
GWG10_19505	COG3025	triphosphatase activity
GWG10_19510	COG1392	Phosphate transport regulator
GWG10_19515	COG0306	phosphate transporter
GWG10_19520	COG0617	tRNA 3'-terminal CCA addition
GWG10_19525	COG3409	Peptidoglycan-binding domain 1 protein
GWG10_19525	COG3267	Type II secretory pathway component ExeA
GWG10_19535	COG1194	a g-specific adenine glycosylase
GWG10_19540	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GWG10_19555	COG3240	lipase activity
GWG10_19565	COG3009	Protein conserved in bacteria
GWG10_19570	COG3008	intermembrane lipid transfer
GWG10_19570	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GWG10_19575	COG2995	paraquat-inducible protein a
GWG10_19585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GWG10_19590	COG5001	Diguanylate cyclase
GWG10_19590	COG2203	Gaf domain
GWG10_19590	COG4251	negative regulation of phosphorylation
GWG10_19590	COG3706	GGDEF domain
GWG10_19595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GWG10_19600	COG2813	Specifically methylates the guanine in position
GWG10_19605	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GWG10_19610	COG0297	glycogen (starch) synthase activity
GWG10_19645	COG1757	Na H antiporter
GWG10_19650	COG0583	DNA-binding transcription factor activity
GWG10_19655	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GWG10_19660	COG3842	ATPase activity
GWG10_19665	COG1176	ABC-type spermidine putrescine transport system, permease component I
GWG10_19670	COG1177	transmembrane transport
GWG10_19675	COG1012	belongs to the aldehyde dehydrogenase family
GWG10_19680	COG0109	protoheme IX farnesyltransferase activity
GWG10_19710	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GWG10_19720	COG1565	acr, cog1565
GWG10_19720	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GWG10_19725	COG1444	tRNA N-acetyltransferase activity
GWG10_19745	COG1803	Methylglyoxal synthase
GWG10_19760	COG0252	asparaginase activity
GWG10_19780	COG1263	PTS System
GWG10_19780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWG10_19785	COG0366	Alpha amylase catalytic
GWG10_19790	COG0110	maltose O-acetyltransferase activity
GWG10_19795	COG1522	sequence-specific DNA binding
GWG10_19825	COG3068	Protein conserved in bacteria
GWG10_19835	COG0739	heme binding
GWG10_19855	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GWG10_19860	COG1121	(ABC) transporter
GWG10_19865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GWG10_19870	COG0583	DNA-binding transcription factor activity
GWG10_19880	COG1573	uracil-dna glycosylase
GWG10_19885	COG2962	Rard protein
GWG10_19890	COG2827	Endonuclease containing a URI domain
GWG10_19905	COG1842	Phage shock protein A
GWG10_19910	COG0204	Acyl-transferase
GWG10_19930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GWG10_19940	COG0484	heat shock protein binding
GWG10_19995	COG1289	transmembrane transporter activity
GWG10_20000	COG1566	PFAM secretion protein HlyD family protein
GWG10_20015	COG1051	belongs to the nudix hydrolase family
GWG10_20020	COG3150	esterase
GWG10_20030	COG3151	Protein conserved in bacteria
GWG10_20035	COG0494	nUDIX hydrolase
GWG10_20040	COG1538	Outer membrane efflux protein
GWG10_20045	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GWG10_20045	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GWG10_20050	COG1560	Kdo2-lipid A biosynthetic process
GWG10_20065	COG2771	luxR family
GWG10_20070	COG3916	Acyl-homoserine-lactone synthase
GWG10_20080	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GWG10_20085	COG2213	PTS system mannitol-specific
GWG10_20085	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWG10_20090	COG0246	Mannitol dehydrogenase
GWG10_20095	COG3722	fumarate hydratase activity
GWG10_20100	COG3263	regulation of cellular component size
GWG10_20120	COG1671	Belongs to the UPF0178 family
GWG10_20135	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GWG10_20140	COG5433	transposase activity
GWG10_20145	COG0513	Belongs to the DEAD box helicase family
GWG10_20165	COG1575	Belongs to the MenA family. Type 1 subfamily
GWG10_20170	COG1169	isochorismate synthase
GWG10_20175	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GWG10_20180	COG0596	Alpha beta hydrolase
GWG10_20185	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GWG10_20195	COG0318	PFAM AMP-dependent synthetase and ligase
GWG10_20200	COG3291	Pkd domain containing protein
GWG10_20205	COG2949	membrane
GWG10_20210	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GWG10_20220	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GWG10_20250	COG2873	o-acetylhomoserine
GWG10_20260	COG1979	alcohol dehydrogenase
GWG10_20275	COG4221	oxidoreductase activity
GWG10_20295	COG1285	pathogenesis
GWG10_20310	COG1368	sulfuric ester hydrolase activity
GWG10_20315	COG1522	sequence-specific DNA binding
GWG10_20325	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GWG10_20335	COG1546	Belongs to the CinA family
GWG10_20335	COG1058	Belongs to the CinA family
GWG10_20340	COG1988	membrane-bound metal-dependent
GWG10_20350	COG0561	phosphatase activity
GWG10_20355	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GWG10_20365	COG1011	Hydrolase
GWG10_20380	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GWG10_20385	COG0019	diaminopimelate decarboxylase activity
GWG10_20395	COG1965	Belongs to the frataxin family
GWG10_20400	COG0400	carboxylic ester hydrolase activity
GWG10_20405	COG3072	Adenylate cyclase
GWG10_20410	COG0181	hydroxymethylbilane synthase activity
GWG10_20420	COG2959	enzyme of heme biosynthesis
GWG10_20425	COG3071	HemY protein
GWG10_20445	COG3028	Belongs to the UPF0307 family
GWG10_20455	COG2926	Belongs to the UPF0265 family
GWG10_20490	COG1396	sequence-specific DNA binding
GWG10_20495	COG3135	benzoate transporter
GWG10_20525	COG3047	cAMP biosynthetic process
GWG10_20530	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GWG10_20535	COG2197	response regulator
GWG10_20545	COG4974	Belongs to the 'phage' integrase family
GWG10_20575	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GWG10_20630	COG0745	RESPONSE REGULATOR receiver
GWG10_20635	COG5002	protein histidine kinase activity
GWG10_20695	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GWG10_20700	COG1304	FMN binding
GWG10_20705	COG0549	Belongs to the carbamate kinase family
GWG10_20710	COG0583	DNA-binding transcription factor activity
GWG10_20740	COG2132	Multicopper oxidase
GWG10_20765	COG5642	Protein of unknown function (DUF2384)
GWG10_20770	COG0659	secondary active sulfate transmembrane transporter activity
GWG10_20775	COG0589	response to stress
GWG10_20795	COG1278	Cold shock
GWG10_20800	COG2205	protein histidine kinase activity
GWG10_20805	COG0745	RESPONSE REGULATOR receiver
GWG10_20825	COG3706	GGDEF domain
GWG10_20830	COG0347	Belongs to the P(II) protein family
GWG10_20835	COG0004	ammonium transporteR
GWG10_20845	COG0346	lactoylglutathione lyase activity
GWG10_20860	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GWG10_20865	COG1074	ATP-dependent DNA helicase activity
GWG10_20870	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GWG10_20875	COG2259	Doxx family
GWG10_20880	COG1741	Belongs to the pirin family
GWG10_20890	COG0583	DNA-binding transcription factor activity
GWG10_20915	COG1175	transmembrane transport
GWG10_20925	COG3842	ATPase activity
GWG10_20955	COG0456	acetyltransferase
GWG10_20960	COG0753	catalase activity
GWG10_20980	COG0494	nUDIX hydrolase
GWG10_20985	COG0628	permease
GWG10_20995	COG2957	Belongs to the agmatine deiminase family
GWG10_21010	COG2957	Belongs to the agmatine deiminase family
GWG10_21015	COG0583	DNA-binding transcription factor activity
GWG10_21030	COG1461	Dihydroxyacetone kinase
GWG10_21035	COG2376	Dihydroxyacetone kinase
GWG10_21040	COG2252	PERMEase
GWG10_21045	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GWG10_21080	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GWG10_21085	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GWG10_21090	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GWG10_21095	COG0049	tRNA binding
GWG10_21100	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GWG10_21105	COG2168	tRNA wobble position uridine thiolation
GWG10_21115	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GWG10_21120	COG0251	oxidation-reduction process
GWG10_21125	COG2964	Protein conserved in bacteria
GWG10_21130	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GWG10_21135	COG0085	RNA polymerase activity
GWG10_21140	COG0222	ribosome binding
GWG10_21145	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GWG10_21150	COG0081	regulation of translation
GWG10_21155	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GWG10_21160	COG0250	Participates in transcription elongation, termination and antitermination
GWG10_21175	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GWG10_21200	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GWG10_21205	COG0569	domain protein
GWG10_21210	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GWG10_21215	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GWG10_21220	COG3005	denitrification pathway
GWG10_21225	COG0243	molybdopterin cofactor binding
GWG10_21240	COG0745	RESPONSE REGULATOR receiver
GWG10_21260	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GWG10_21275	COG2204	response regulator
GWG10_21285	COG2205	protein histidine kinase activity
GWG10_21305	COG0517	IMP dehydrogenase activity
GWG10_21305	COG0516	GMP reductase activity
GWG10_21315	COG1522	sequence-specific DNA binding
GWG10_21320	COG2502	aspartate--ammonia ligase
GWG10_21335	COG0583	DNA-binding transcription factor activity
GWG10_21340	COG0542	response to heat
GWG10_21350	COG0564	pseudouridine synthase activity
GWG10_21355	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GWG10_21360	COG3681	Belongs to the UPF0597 family
GWG10_21365	COG2964	Protein conserved in bacteria
GWG10_21370	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GWG10_21375	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GWG10_21380	COG1979	alcohol dehydrogenase
GWG10_21385	COG2207	Transcriptional regulator
GWG10_21390	COG3040	lipid binding
GWG10_21410	COG0583	DNA-binding transcription factor activity
GWG10_21430	COG0540	Belongs to the ATCase OTCase family
GWG10_21435	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GWG10_21440	COG1438	arginine binding
GWG10_21445	COG1288	antiporter activity
GWG10_21450	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GWG10_21485	COG3250	beta-galactosidase activity
GWG10_21495	COG1609	Transcriptional regulator
GWG10_21500	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GWG10_21510	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GWG10_21515	COG2017	converts alpha-aldose to the beta-anomer
GWG10_21520	COG0667	Aldo Keto reductase
GWG10_21525	COG1968	undecaprenyl-diphosphatase activity
GWG10_21530	COG3806	Anti-sigma factor
GWG10_21535	COG1595	DNA-templated transcription, initiation
GWG10_21555	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GWG10_21560	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GWG10_21580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GWG10_21585	COG1131	(ABC) transporter
GWG10_21590	COG0842	Transport permease protein
GWG10_21595	COG0842	Transport permease protein
GWG10_21600	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GWG10_21610	COG2116	formate transmembrane transporter activity
GWG10_21615	COG1648	precorrin-2 dehydrogenase activity
GWG10_21615	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GWG10_21620	COG2239	Acts as a magnesium transporter
GWG10_21625	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GWG10_21635	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GWG10_21645	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GWG10_21655	COG0514	ATP-dependent DNA helicase (RecQ)
GWG10_21660	COG2050	protein possibly involved in aromatic compounds catabolism
GWG10_21675	COG2258	MOSC domain
GWG10_21680	COG1177	transmembrane transport
GWG10_21685	COG1176	ABC-type spermidine putrescine transport system, permease component I
GWG10_21690	COG3842	ATPase activity
GWG10_21710	COG0174	glutamine synthetase
GWG10_21730	COG3045	CreA protein
GWG10_21735	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GWG10_21740	COG0443	Heat shock 70 kDa protein
GWG10_21755	COG0366	Alpha amylase catalytic
GWG10_21770	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GWG10_21775	COG0745	RESPONSE REGULATOR receiver
GWG10_21785	COG2205	protein histidine kinase activity
GWG10_21795	COG0281	malic enzyme
GWG10_21800	COG0702	epimerase
GWG10_21805	COG0254	rRNA binding
GWG10_21810	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GWG10_21815	COG1309	transcriptional regulator
GWG10_21835	COG0129	dihydroxy-acid dehydratase activity
GWG10_21845	COG3978	acetolactate synthase activity
GWG10_21860	COG0606	chelatase, subunit chli
GWG10_21865	COG0204	Acyl-transferase
GWG10_21870	COG0204	Acyl-transferase
GWG10_21875	COG1683	Conserved Protein
GWG10_21885	COG1335	isochorismatase
GWG10_21895	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GWG10_21900	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GWG10_21910	COG3084	Protein conserved in bacteria
GWG10_21915	COG2203	Gaf domain
GWG10_21915	COG4251	negative regulation of phosphorylation
GWG10_21915	COG3706	GGDEF domain
GWG10_21915	COG5001	Diguanylate cyclase
GWG10_21930	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GWG10_21940	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GWG10_21945	COG1561	YicC-like family, N-terminal region
GWG10_21955	COG1519	Transferase
GWG10_21960	COG0859	PFAM glycosyl transferase family 9
GWG10_21965	COG0463	Glycosyl transferase, family 2
GWG10_21970	COG0859	PFAM glycosyl transferase family 9
GWG10_21975	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GWG10_21980	COG2990	Protein conserved in bacteria
GWG10_21985	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GWG10_21995	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GWG10_22000	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GWG10_22005	COG2003	Belongs to the UPF0758 family
GWG10_22010	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GWG10_22015	COG0756	dUTP diphosphatase activity
GWG10_22020	COG1309	transcriptional regulator
GWG10_22030	COG0668	transmembrane transport
GWG10_22040	COG0166	Belongs to the GPI family
GWG10_22045	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GWG10_22050	COG0583	DNA-binding transcription factor activity
GWG10_22060	COG0045	succinate-CoA ligase (ADP-forming) activity
GWG10_22060	COG1042	CoA-binding domain protein
GWG10_22060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GWG10_22085	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
GWG10_22090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GWG10_22095	COG1739	Uncharacterized protein family UPF0029
GWG10_22100	COG0006	proline dipeptidase activity
GWG10_22105	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GWG10_22110	COG1250	3-hydroxyacyl-CoA dehydrogenase
GWG10_22110	COG1024	Enoyl-CoA hydratase
GWG10_22115	COG0183	Belongs to the thiolase family
GWG10_22120	COG0745	RESPONSE REGULATOR receiver
GWG10_22155	COG0425	Belongs to the sulfur carrier protein TusA family
GWG10_22160	COG0251	oxidation-reduction process
GWG10_22180	COG2885	chlorophyll binding
GWG10_22190	COG1335	isochorismatase
GWG10_22195	COG2818	Glycosylase
GWG10_22200	COG0752	glycyl-tRNA synthetase alpha subunit
GWG10_22205	COG0751	glycine-tRNA ligase activity
GWG10_22230	COG2203	Gaf domain
GWG10_22230	COG3706	GGDEF domain
GWG10_22230	COG4251	negative regulation of phosphorylation
GWG10_22230	COG5001	Diguanylate cyclase
GWG10_22250	COG0814	amino acid
GWG10_22255	COG0814	amino acid
GWG10_22260	COG3033	Beta-eliminating lyase
GWG10_22270	COG0348	domain, Protein
GWG10_22280	COG0446	pyridine nucleotide-disulphide oxidoreductase
GWG10_22285	COG1773	rubredoxin
GWG10_22285	COG0426	domain, Protein
GWG10_22290	COG3604	Transcriptional regulator
GWG10_22295	COG1609	Transcriptional regulator
GWG10_22335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GWG10_22350	COG2960	long-chain fatty acid transporting porin activity
GWG10_22360	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GWG10_22375	COG3118	belongs to the thioredoxin family
GWG10_22380	COG0513	Belongs to the DEAD box helicase family
GWG10_22385	COG0248	Ppx GppA phosphatase
GWG10_22395	COG0742	ribosomal rna small subunit methyltransferase
GWG10_22415	COG0084	hydrolase, TatD family'
GWG10_22420	COG0805	protein transport
GWG10_22425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GWG10_22430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GWG10_22435	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GWG10_22440	COG3165	ubiquinone biosynthetic process from chorismate
GWG10_22450	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GWG10_22455	COG0402	S-adenosylhomocysteine deaminase activity
GWG10_22495	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GWG10_22500	COG0848	biopolymer transport protein
GWG10_22505	COG0811	peptide transport
GWG10_22510	COG0811	peptide transport
GWG10_22520	COG2771	luxR family
GWG10_22535	COG1349	DNA-binding transcription factor activity
GWG10_22545	COG1028	Short-chain dehydrogenase reductase Sdr
GWG10_22580	COG0166	Belongs to the GPI family
GWG10_22585	COG3039	Transposase
GWG10_22590	COG3039	Transposase
GWG10_22605	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GWG10_22610	COG1349	DNA-binding transcription factor activity
GWG10_22615	COG0745	RESPONSE REGULATOR receiver
GWG10_22620	COG2205	protein histidine kinase activity
GWG10_22630	COG4452	Inner membrane protein CreD
GWG10_22635	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GWG10_22640	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GWG10_22645	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GWG10_22650	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GWG10_22655	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GWG10_22660	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GWG10_22665	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GWG10_22675	COG0356	it plays a direct role in the translocation of protons across the membrane
GWG10_22685	COG1475	DNA binding
GWG10_22690	COG1192	Involved in chromosome partitioning
GWG10_22695	COG0357	Ribosomal RNA small subunit methyltransferase G
GWG10_22700	COG0445	tRNA wobble uridine modification
GWG10_22705	COG0716	FMN binding
GWG10_22710	COG4774	siderophore transport
GWG10_22715	COG4615	Cyclic peptide transporter
GWG10_22720	COG1120	ATPase activity
GWG10_22725	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GWG10_22735	COG3550	peptidyl-serine autophosphorylation
GWG10_22760	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GWG10_22765	COG0706	membrane insertase activity
GWG10_22770	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GWG10_22775	COG0594	ribonuclease P activity
GWG10_22780	COG0230	Belongs to the bacterial ribosomal protein bL34 family