locus-tag	class	description
LEO79_00010	COG4695	Portal protein
LEO79_00115	COG4974	Belongs to the 'phage' integrase family
LEO79_00120	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LEO79_00125	COG0072	phenylalanine-tRNA ligase activity
LEO79_00125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LEO79_00130	COG0776	regulation of translation
LEO79_00160	COG3300	MHYT domain
LEO79_00160	COG5001	Diguanylate cyclase
LEO79_00170	COG1609	Transcriptional regulator
LEO79_00175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LEO79_00180	COG1879	ABC-type sugar transport system periplasmic component
LEO79_00185	COG1172	Belongs to the binding-protein-dependent transport system permease family
LEO79_00190	COG1129	ABC transporter
LEO79_00195	COG1869	D-ribose catabolic process
LEO79_00200	COG0625	glutathione transferase activity
LEO79_00215	COG0037	tRNA processing
LEO79_00220	COG0589	response to stress
LEO79_00225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LEO79_00240	COG2217	Heavy metal translocating P-type atpase
LEO79_00250	COG2010	Cytochrome c
LEO79_00265	COG3278	Belongs to the heme-copper respiratory oxidase family
LEO79_00275	COG1956	GAF domain-containing protein
LEO79_00280	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
LEO79_00290	COG0308	aminopeptidase N
LEO79_00300	COG2902	Dehydrogenase
LEO79_00305	COG0167	dihydroorotate dehydrogenase activity
LEO79_00315	COG0116	Belongs to the methyltransferase superfamily
LEO79_00315	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LEO79_00325	COG0488	(ABC) transporter
LEO79_00340	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LEO79_00345	COG1067	ATP-dependent peptidase activity
LEO79_00355	COG3141	response to X-ray
LEO79_00365	COG2995	paraquat-inducible protein a
LEO79_00370	COG3008	intermembrane lipid transfer
LEO79_00375	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LEO79_00375	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LEO79_00390	COG0084	hydrolase, TatD family'
LEO79_00395	COG0470	DNA polymerase III
LEO79_00400	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LEO79_00405	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LEO79_00410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LEO79_00415	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LEO79_00420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LEO79_00425	COG1028	Short-chain dehydrogenase reductase Sdr
LEO79_00435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LEO79_00440	COG0416	fatty acid biosynthetic process
LEO79_00445	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LEO79_00450	COG1399	metal-binding, possibly nucleic acid-binding protein
LEO79_00465	COG0564	pseudouridine synthase activity
LEO79_00470	COG1530	ribonuclease E activity
LEO79_00475	COG0306	phosphate transporter
LEO79_00480	COG0717	Belongs to the dCTP deaminase family
LEO79_00485	COG0572	uridine kinase
LEO79_00490	COG0489	protein tyrosine kinase activity
LEO79_00495	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LEO79_00495	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LEO79_00505	COG1254	Belongs to the acylphosphatase family
LEO79_00510	COG0840	transmembrane signaling receptor activity
LEO79_00515	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LEO79_00525	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LEO79_00540	COG0709	Synthesizes selenophosphate from selenide and ATP
LEO79_00545	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
LEO79_00550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LEO79_00555	COG3437	response regulator, receiver
LEO79_00565	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LEO79_00575	COG1643	Atp-dependent helicase
LEO79_00580	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LEO79_00580	COG0517	IMP dehydrogenase activity
LEO79_00580	COG0617	tRNA 3'-terminal CCA addition
LEO79_00585	COG2197	response regulator
LEO79_00590	COG3314	Sporulation integral membrane protein YlbJ
LEO79_00600	COG0583	DNA-binding transcription factor activity
LEO79_00605	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LEO79_00615	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LEO79_00620	COG2832	Protein of unknown function (DUF454)
LEO79_00625	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LEO79_00635	COG0697	spore germination
LEO79_00645	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LEO79_00650	COG0318	PFAM AMP-dependent synthetase and ligase
LEO79_00655	COG0596	Alpha beta hydrolase
LEO79_00665	COG1214	PFAM Peptidase M22, glycoprotease
LEO79_00670	COG1199	ATP-dependent helicase activity
LEO79_00680	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LEO79_00685	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LEO79_00690	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LEO79_00695	COG0131	Imidazoleglycerol-phosphate dehydratase
LEO79_00695	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LEO79_00700	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LEO79_00705	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LEO79_00710	COG3437	response regulator, receiver
LEO79_00715	COG2199	diguanylate cyclase activity
LEO79_00720	COG2198	Histidine kinase
LEO79_00720	COG2205	protein histidine kinase activity
LEO79_00720	COG0784	Response regulator, receiver
LEO79_00725	COG0107	imidazoleglycerol-phosphate synthase activity
LEO79_00730	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LEO79_00730	COG0140	phosphoribosyl-ATP diphosphatase activity
LEO79_00740	COG2378	regulation of single-species biofilm formation
LEO79_00745	COG0318	PFAM AMP-dependent synthetase and ligase
LEO79_00750	COG3134	Outer membrane lipoprotein
LEO79_00765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEO79_00785	COG4681	YaeQ
LEO79_00795	COG1250	3-hydroxyacyl-CoA dehydrogenase
LEO79_00795	COG1024	Enoyl-CoA hydratase
LEO79_00800	COG0183	Belongs to the thiolase family
LEO79_00805	COG0714	Associated with various cellular activities
LEO79_00835	COG1595	DNA-templated transcription, initiation
LEO79_00845	COG2067	long-chain fatty acid transport protein
LEO79_00850	COG2067	long-chain fatty acid transport protein
LEO79_00855	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LEO79_00870	COG1301	dicarboxylic acid transport
LEO79_00875	COG3123	guanosine phosphorylase activity
LEO79_00880	COG1760	l-serine dehydratase
LEO79_00885	COG1760	l-serine dehydratase
LEO79_00890	COG2951	lytic endotransglycosylase activity
LEO79_00895	COG3100	YcgL domain-containing protein
LEO79_00900	COG0850	regulation of cytokinetic process
LEO79_00905	COG2894	cell division
LEO79_00910	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LEO79_00915	COG3099	Belongs to the UPF0263 family
LEO79_00920	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LEO79_00935	COG2996	Protein conserved in bacteria
LEO79_00960	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LEO79_00965	COG0697	spore germination
LEO79_00970	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LEO79_00975	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LEO79_00990	COG0307	riboflavin synthase, alpha
LEO79_01000	COG0534	Mate efflux family protein
LEO79_01030	COG0417	DNA replication proofreading
LEO79_01045	COG1560	Kdo2-lipid A biosynthetic process
LEO79_01050	COG1560	Kdo2-lipid A biosynthetic process
LEO79_01060	COG0583	DNA-binding transcription factor activity
LEO79_01065	COG0673	inositol 2-dehydrogenase activity
LEO79_01070	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LEO79_01090	COG0583	DNA-binding transcription factor activity
LEO79_01100	COG2723	6-phospho-beta-galactosidase activity
LEO79_01105	COG0583	DNA-binding transcription factor activity
LEO79_01115	COG0243	molybdopterin cofactor binding
LEO79_01120	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LEO79_01135	COG1879	ABC-type sugar transport system periplasmic component
LEO79_01140	COG1129	ABC transporter
LEO79_01145	COG1172	Belongs to the binding-protein-dependent transport system permease family
LEO79_01150	COG1172	Belongs to the binding-protein-dependent transport system permease family
LEO79_01160	COG2249	NAD(P)H dehydrogenase (quinone) activity
LEO79_01165	COG2807	transmembrane transport
LEO79_01185	COG0583	DNA-binding transcription factor activity
LEO79_01190	COG2207	Transcriptional regulator
LEO79_01200	COG0730	response to heat
LEO79_01210	COG1028	Short-chain dehydrogenase reductase Sdr
LEO79_01220	COG1024	Enoyl-CoA hydratase
LEO79_01225	COG1024	Enoyl-CoA hydratase
LEO79_01230	COG1960	acyl-CoA dehydrogenase activity
LEO79_01240	COG1960	acyl-CoA dehydrogenase activity
LEO79_01245	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LEO79_01250	COG1024	Enoyl-CoA hydratase
LEO79_01275	COG1584	GPR1 FUN34 yaaH family protein
LEO79_01280	COG3228	Belongs to the MtfA family
LEO79_01290	COG1115	amino acid carrier protein
LEO79_01295	COG1024	Enoyl-CoA hydratase
LEO79_01310	COG3162	membrane
LEO79_01315	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LEO79_01320	COG0488	(ABC) transporter
LEO79_01325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LEO79_01330	COG0776	regulation of translation
LEO79_01335	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LEO79_01340	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LEO79_01345	COG0740	serine-type endopeptidase activity
LEO79_01350	COG0544	peptidyl-prolyl cis-trans isomerase activity
LEO79_01360	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LEO79_01365	COG4591	ABC-type transport system involved in lipoprotein release permease component
LEO79_01370	COG1136	(ABC) transporter
LEO79_01375	COG4591	ABC-type transport system involved in lipoprotein release permease component
LEO79_01385	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LEO79_01390	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LEO79_01405	COG0697	spore germination
LEO79_01415	COG2062	phosphohistidine phosphatase, SixA
LEO79_01425	COG0500	methyltransferase
LEO79_01435	COG1846	Transcriptional regulator
LEO79_01470	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LEO79_01470	COG0519	Catalyzes the synthesis of GMP from XMP
LEO79_01475	COG0516	GMP reductase activity
LEO79_01475	COG0517	IMP dehydrogenase activity
LEO79_01485	COG1874	Beta-galactosidase
LEO79_01485	COG0366	Alpha amylase catalytic
LEO79_01510	COG1570	exodeoxyribonuclease VII activity
LEO79_01520	COG2885	chlorophyll binding
LEO79_01540	COG2154	pterin-4-alpha-carbinolamine dehydratase
LEO79_01550	COG3768	UPF0283 membrane protein
LEO79_01555	COG3106	COG3106 Predicted ATPase
LEO79_01570	COG1842	Phage shock protein A
LEO79_01575	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LEO79_01590	COG4171	peptide transport system, permease
LEO79_01600	COG4172	Belongs to the ABC transporter superfamily
LEO79_01615	COG1609	Transcriptional regulator
LEO79_01620	COG1263	PTS System
LEO79_01620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LEO79_01625	COG2723	6-phospho-beta-galactosidase activity
LEO79_01630	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LEO79_01635	COG1286	toxin biosynthetic process
LEO79_01640	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LEO79_01645	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LEO79_01650	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LEO79_01655	COG0531	amino acid
LEO79_01655	COG1674	ftsk spoiiie
LEO79_01665	COG0686	Belongs to the AlaDH PNT family
LEO79_01670	COG0492	ferredoxin-NADP+ reductase activity
LEO79_01675	COG3706	GGDEF domain
LEO79_01680	COG3134	Outer membrane lipoprotein
LEO79_01685	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LEO79_01690	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
LEO79_01695	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LEO79_01700	COG0542	response to heat
LEO79_01705	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LEO79_01710	COG1278	Cold shock
LEO79_01715	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LEO79_01730	COG1944	ATP diphosphatase activity
LEO79_01735	COG2116	formate transmembrane transporter activity
LEO79_01740	COG1882	Formate acetyltransferase
LEO79_01745	COG2983	Belongs to the UPF0260 family
LEO79_01755	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LEO79_01760	COG0045	succinate-CoA ligase (ADP-forming) activity
LEO79_01765	COG0508	dehydrogenase complex catalyzes the overall conversion of
LEO79_01770	COG0567	Dehydrogenase, E1 component
LEO79_01785	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LEO79_01790	COG2009	succinate dehydrogenase
LEO79_01810	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LEO79_01815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LEO79_01815	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
LEO79_01825	COG3069	C4-dicarboxylate transmembrane transporter activity
LEO79_01840	COG1451	nucleotide metabolic process
LEO79_01855	COG0254	rRNA binding
LEO79_01860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LEO79_01870	COG1172	Belongs to the binding-protein-dependent transport system permease family
LEO79_01875	COG1129	ABC transporter
LEO79_01880	COG1879	ABC-type sugar transport system periplasmic component
LEO79_01885	COG1069	ribulokinase activity
LEO79_01895	COG2160	L-arabinose isomerase activity
LEO79_01900	COG0583	DNA-binding transcription factor activity
LEO79_01905	COG0436	Aminotransferase
LEO79_01910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LEO79_01925	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LEO79_01925	COG0392	lysyltransferase activity
LEO79_01930	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LEO79_01940	COG0469	pyruvate kinase activity
LEO79_01950	COG1263	PTS System
LEO79_01950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LEO79_01955	COG1874	Beta-galactosidase
LEO79_01960	COG3867	Arabinogalactan endo-beta-1,4-galactanase
LEO79_01965	COG3833	ABC-type maltose transport systems, permease component
LEO79_01970	COG1175	transmembrane transport
LEO79_01975	COG2182	Extracellular solute-binding protein
LEO79_02000	COG4580	involved in the transport of maltose and maltodextrins
LEO79_02005	COG1609	Transcriptional regulator
LEO79_02010	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LEO79_02015	COG1085	galactose-1-phosphate uridylyltransferase
LEO79_02040	COG0300	oxidoreductase activity
LEO79_02045	COG1902	pentaerythritol trinitrate reductase activity
LEO79_02075	COG2925	Exonuclease
LEO79_02085	COG3345	alpha-galactosidase
LEO79_02090	COG1380	Effector of murein hydrolase LrgA
LEO79_02095	COG1346	cytolysis
LEO79_02100	COG0295	cytidine deaminase activity
LEO79_02105	COG1022	Amp-dependent synthetase and ligase
LEO79_02120	COG0861	Integral membrane protein TerC family
LEO79_02125	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LEO79_02130	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LEO79_02135	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LEO79_02175	COG4771	TonB-dependent receptor
LEO79_02180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEO79_02185	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEO79_02190	COG1120	ATPase activity
LEO79_02205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LEO79_02215	COG1028	Short-chain dehydrogenase reductase Sdr
LEO79_02220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LEO79_02225	COG1535	isochorismatase
LEO79_02225	COG3433	isochorismatase activity
LEO79_02230	COG1021	2,3-dihydroxybenzoate-AMP ligase
LEO79_02255	COG3300	MHYT domain
LEO79_02255	COG5001	Diguanylate cyclase
LEO79_02270	COG0840	transmembrane signaling receptor activity
LEO79_02275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LEO79_02280	COG3788	relative of glutathione S-transferase, MAPEG superfamily
LEO79_02285	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LEO79_02290	COG0563	adenylate kinase activity
LEO79_02295	COG0326	Molecular chaperone. Has ATPase activity
LEO79_02300	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LEO79_02310	COG3158	transport of potassium into the cell
LEO79_02315	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
LEO79_02320	COG0298	carbon dioxide binding
LEO79_02330	COG0309	Hydrogenase expression formation protein (HypE)
LEO79_02335	COG0375	protein maturation
LEO79_02350	COG3842	ATPase activity
LEO79_02355	COG0444	Belongs to the ABC transporter superfamily
LEO79_02360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEO79_02375	COG1773	rubredoxin
LEO79_02380	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LEO79_02385	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
LEO79_02390	COG5557	Pfam Polysulphide reductase, NrfD
LEO79_02395	COG0437	4 iron, 4 sulfur cluster binding
LEO79_02400	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
LEO79_02405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LEO79_02420	COG0659	secondary active sulfate transmembrane transporter activity
LEO79_02440	COG2308	Evidence 4 Homologs of previously reported genes of
LEO79_02475	COG0672	)-iron permease
LEO79_02495	COG2814	Major facilitator Superfamily
LEO79_02515	COG1136	(ABC) transporter
LEO79_02520	COG0577	efflux transmembrane transporter activity
LEO79_02550	COG1139	Iron-sulfur cluster binding protein
LEO79_02555	COG0247	lactate metabolic process
LEO79_02560	COG1620	l-lactate permease
LEO79_02565	COG0583	DNA-binding transcription factor activity
LEO79_02590	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LEO79_02595	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LEO79_02595	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LEO79_02600	COG0527	aspartate kinase activity
LEO79_02610	COG1368	sulfuric ester hydrolase activity
LEO79_02615	COG1619	proteins homologs of microcin C7 resistance protein MccF
LEO79_02620	COG0393	Putative heavy-metal-binding
LEO79_02630	COG1252	NADH dehydrogenase
LEO79_02635	COG3150	esterase
LEO79_02645	COG1164	Oligoendopeptidase f
LEO79_02650	COG2354	Protein conserved in bacteria
LEO79_02665	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LEO79_02670	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LEO79_02705	COG0537	adenosine 5'-monophosphoramidase activity
LEO79_02720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LEO79_02740	COG1301	dicarboxylic acid transport
LEO79_02750	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LEO79_02755	COG0861	Integral membrane protein TerC family
LEO79_02770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEO79_02775	COG0601	transmembrane transport
LEO79_02785	COG2095	MarC family integral membrane protein
LEO79_02790	COG1454	alcohol dehydrogenase
LEO79_02790	COG1012	belongs to the aldehyde dehydrogenase family
LEO79_02800	COG3275	phosphorelay sensor kinase activity
LEO79_02805	COG3279	Response regulator of the LytR AlgR family
LEO79_02810	COG1966	Carbon starvation protein
LEO79_02815	COG3264	Mechanosensitive ion channel
LEO79_02815	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LEO79_02825	COG1566	PFAM secretion protein HlyD family protein
LEO79_02830	COG1061	Type III restriction enzyme res subunit
LEO79_02835	COG2027	D-alanyl-D-alanine carboxypeptidase
LEO79_02840	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LEO79_02850	COG0436	Aminotransferase
LEO79_02855	COG1288	antiporter activity
LEO79_02860	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LEO79_02885	COG0697	spore germination
LEO79_02890	COG4657	Part of a membrane complex involved in electron transport
LEO79_02895	COG2878	Part of a membrane complex involved in electron transport
LEO79_02905	COG4658	electron transport chain
LEO79_02910	COG4659	FMN binding
LEO79_02915	COG4660	Part of a membrane complex involved in electron transport
LEO79_02920	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LEO79_02925	COG0346	lactoylglutathione lyase activity
LEO79_02945	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LEO79_02955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LEO79_02960	COG2801	Transposase and inactivated derivatives
LEO79_02970	COG1083	cytidylyl-transferase
LEO79_02985	COG2089	acid synthase
LEO79_02990	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LEO79_02995	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LEO79_03030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LEO79_03035	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LEO79_03050	COG0301	tRNA thio-modification
LEO79_03050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LEO79_03060	COG4953	penicillin-binding protein 1C
LEO79_03065	COG2373	Large extracellular alpha-helical protein
LEO79_03070	COG0628	permease
LEO79_03095	COG0446	pyridine nucleotide-disulphide oxidoreductase
LEO79_03105	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LEO79_03115	COG4160	amino acid transport
LEO79_03125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LEO79_03135	COG2431	L-lysine efflux transmembrane transporter activity
LEO79_03140	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LEO79_03145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LEO79_03170	COG1393	Belongs to the ArsC family
LEO79_03180	COG4783	chaperone-mediated protein folding
LEO79_03185	COG0425	Belongs to the sulfur carrier protein TusA family
LEO79_03200	COG0596	Alpha beta hydrolase
LEO79_03210	COG3842	ATPase activity
LEO79_03215	COG3833	ABC-type maltose transport systems, permease component
LEO79_03220	COG1175	transmembrane transport
LEO79_03230	COG3081	Nucleoid-associated protein
LEO79_03235	COG3082	Protein of unknown function (DUF1414)
LEO79_03240	COG3083	sulfuric ester hydrolase activity
LEO79_03245	COG4771	TonB-dependent receptor
LEO79_03250	COG1770	oligopeptidase
LEO79_03270	COG4574	serine-type endopeptidase inhibitor activity
LEO79_03275	COG3085	chromosome segregation
LEO79_03285	COG0287	Prephenate dehydrogenase
LEO79_03285	COG1605	Chorismate mutase
LEO79_03290	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LEO79_03295	COG0584	glycerophosphoryl diester phosphodiesterase
LEO79_03305	COG1349	DNA-binding transcription factor activity
LEO79_03310	COG2271	Major facilitator Superfamily
LEO79_03315	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LEO79_03320	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LEO79_03325	COG0583	DNA-binding transcription factor activity
LEO79_03360	COG0656	L-ascorbic acid biosynthetic process
LEO79_03365	COG2814	Major facilitator Superfamily
LEO79_03375	COG1294	oxidase, subunit
LEO79_03385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LEO79_03395	COG2979	Protein of unknown function (DUF533)
LEO79_03415	COG0583	DNA-binding transcription factor activity
LEO79_03425	COG2807	transmembrane transport
LEO79_03435	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LEO79_03455	COG1061	Type III restriction enzyme res subunit
LEO79_03480	COG1166	arginine decarboxylase activity
LEO79_03485	COG2195	Cleaves the N-terminal amino acid of tripeptides
LEO79_03500	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LEO79_03515	COG0583	DNA-binding transcription factor activity
LEO79_03525	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LEO79_03530	COG0840	transmembrane signaling receptor activity
LEO79_03535	COG0302	gtp cyclohydrolase
LEO79_03545	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LEO79_03555	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LEO79_03570	COG0314	molybdopterin synthase activity
LEO79_03575	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LEO79_03580	COG0315	cyclic pyranopterin monophosphate synthase activity
LEO79_03585	COG0521	Mo-molybdopterin cofactor biosynthetic process
LEO79_03590	COG3005	denitrification pathway
LEO79_03600	COG0348	domain, Protein
LEO79_03605	COG0437	4 iron, 4 sulfur cluster binding
LEO79_03610	COG0243	molybdopterin cofactor binding
LEO79_03620	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LEO79_03620	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
LEO79_03625	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LEO79_03630	COG3850	Histidine kinase
LEO79_03635	COG2197	response regulator
LEO79_03660	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LEO79_03670	COG0121	glutamine amidotransferase
LEO79_03675	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LEO79_03680	COG1960	acyl-CoA dehydrogenase activity
LEO79_03685	COG0784	Response regulator, receiver
LEO79_03685	COG3437	response regulator, receiver
LEO79_03695	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LEO79_03700	COG0328	RNA-DNA hybrid ribonuclease activity
LEO79_03705	COG2226	methyltransferase
LEO79_03710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LEO79_03720	COG0741	lytic transglycosylase activity
LEO79_03720	COG1388	LysM domain
LEO79_03735	COG1607	acyl-coa hydrolase
LEO79_03750	COG0741	lytic transglycosylase activity
LEO79_03760	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LEO79_03785	COG0729	surface antigen
LEO79_03795	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LEO79_03805	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LEO79_03810	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LEO79_03815	COG4134	Bacterial extracellular solute-binding protein
LEO79_03825	COG4136	ATPase activity
LEO79_03830	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LEO79_03835	COG2951	lytic endotransglycosylase activity
LEO79_03840	COG1846	Transcriptional regulator
LEO79_03850	COG0033	Phosphoglucomutase
LEO79_03855	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
LEO79_03860	COG0596	Alpha beta hydrolase
LEO79_03875	COG0716	FMN binding
LEO79_03885	COG0735	belongs to the Fur family
LEO79_03890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LEO79_03900	COG2190	(PTS) system
LEO79_03900	COG1263	PTS System
LEO79_03900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LEO79_03905	COG0363	glucosamine-6-phosphate deaminase activity
LEO79_03910	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LEO79_03915	COG1846	Transcriptional regulator
LEO79_03915	COG1940	carbohydrate kinase activity
LEO79_03920	COG2194	sulfuric ester hydrolase activity
LEO79_03925	COG0217	transcriptional regulatory protein
LEO79_03930	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LEO79_03935	COG1801	Protein of unknown function DUF72
LEO79_03940	COG4106	trans-aconitate 2-methyltransferase activity
LEO79_03945	COG0500	methyltransferase
LEO79_03965	COG0583	DNA-binding transcription factor activity
LEO79_03970	COG0791	NLP P60 protein
LEO79_03985	COG1309	transcriptional regulator
LEO79_03995	COG1454	alcohol dehydrogenase
LEO79_04020	COG0534	Mate efflux family protein
LEO79_04035	COG2841	Protein conserved in bacteria
LEO79_04050	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LEO79_04050	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LEO79_04050	COG1013	pyruvate-flavodoxin oxidoreductase activity
LEO79_04050	COG0674	pyruvate-flavodoxin oxidoreductase activity
LEO79_04060	COG0633	Ferredoxin
LEO79_04060	COG3217	Mosc domain protein beta barrel domain protein
LEO79_04060	COG3217	Mosc domain protein beta barrel domain protein
LEO79_04060	COG0633	Ferredoxin
LEO79_04065	COG0501	Belongs to the peptidase M48B family
LEO79_04070	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LEO79_04075	COG2226	methyltransferase
LEO79_04075	COG1073	alpha beta
LEO79_04080	COG0156	8-amino-7-oxononanoate synthase activity
LEO79_04085	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LEO79_04105	COG0017	Asparaginyl-tRNA synthetase
LEO79_04110	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LEO79_04120	COG1473	amidohydrolase
LEO79_04125	COG3069	C4-dicarboxylate transmembrane transporter activity
LEO79_04135	COG1393	Belongs to the ArsC family
LEO79_04140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LEO79_04145	COG1876	peptidase activity
LEO79_04155	COG3263	regulation of cellular component size
LEO79_04165	COG1280	lysine exporter protein (LysE YggA)
LEO79_04190	COG1957	nucleoside hydrolase
LEO79_04195	COG0564	pseudouridine synthase activity
LEO79_04205	COG2801	Transposase and inactivated derivatives
LEO79_04230	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LEO79_04235	COG0702	epimerase
LEO79_04240	COG2914	Belongs to the UPF0125 (RnfH) family
LEO79_04245	COG2867	negative regulation of translational initiation
LEO79_04250	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LEO79_04260	COG0582	viral genome integration into host DNA
LEO79_04265	COG2801	Transposase and inactivated derivatives
LEO79_04290	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LEO79_04295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEO79_04305	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LEO79_04360	COG0246	Mannitol dehydrogenase
LEO79_04365	COG2721	sulfolactate sulfo-lyase activity
LEO79_04375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LEO79_04380	COG0800	Aldolase
LEO79_04395	COG3153	acetyltransferase
LEO79_04425	COG0583	DNA-binding transcription factor activity
LEO79_04430	COG0259	pyridoxamine-phosphate oxidase activity
LEO79_04445	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LEO79_04445	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LEO79_04450	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LEO79_04470	COG0457	Tetratricopeptide repeat
LEO79_04480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LEO79_04485	COG1138	Cytochrome C-type biogenesis protein
LEO79_04490	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LEO79_04495	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LEO79_04500	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LEO79_04505	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LEO79_04520	COG0835	chemotaxis
LEO79_04530	COG1192	Involved in chromosome partitioning
LEO79_04535	COG1360	Flagellar Motor Protein
LEO79_04540	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LEO79_04545	COG2201	protein-glutamate methylesterase activity
LEO79_04550	COG0643	Histidine kinase
LEO79_04550	COG2198	Histidine kinase
LEO79_04550	COG0784	Response regulator, receiver
LEO79_04555	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
LEO79_04580	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LEO79_04590	COG1684	flagellar biosynthetic protein fliR
LEO79_04645	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LEO79_04655	COG1677	Flagellar hook-basal body complex protein FliE
LEO79_04670	COG1393	Belongs to the ArsC family
LEO79_04675	COG0798	PFAM Bile acid sodium symporter
LEO79_04680	COG0640	Transcriptional regulator
LEO79_04690	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LEO79_04705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEO79_04710	COG0444	Belongs to the ABC transporter superfamily
LEO79_04715	COG4608	Belongs to the ABC transporter superfamily
LEO79_04725	COG2971	BadF BadG BcrA BcrD
LEO79_04735	COG0840	transmembrane signaling receptor activity
LEO79_04755	COG3724	N-succinylarginine dihydrolase activity
LEO79_04760	COG0616	signal peptide processing
LEO79_04765	COG1028	Short-chain dehydrogenase reductase Sdr
LEO79_04770	COG0583	DNA-binding transcription factor activity
LEO79_04780	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LEO79_04790	COG0583	DNA-binding transcription factor activity
LEO79_04795	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LEO79_04800	COG1881	PFAM PEBP family protein
LEO79_04810	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
LEO79_04810	COG3408	Glycogen debranching enzyme
LEO79_04815	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LEO79_04820	COG0739	heme binding
LEO79_04825	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LEO79_04855	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LEO79_04865	COG3091	SprT-like family
LEO79_04875	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LEO79_04880	COG0189	ligase activity
LEO79_04890	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LEO79_04910	COG1115	amino acid carrier protein
LEO79_04915	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LEO79_04930	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LEO79_04940	COG1301	dicarboxylic acid transport
LEO79_04945	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LEO79_04950	COG2912	Transglutaminase-like superfamily
LEO79_04960	COG2890	protein-(glutamine-N5) methyltransferase activity
LEO79_04965	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LEO79_04970	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LEO79_04975	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LEO79_04980	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LEO79_04990	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LEO79_04995	COG0193	aminoacyl-tRNA hydrolase activity
LEO79_05000	COG0012	GTP binding
LEO79_05045	COG0490	domain, Protein
LEO79_05045	COG0471	metal ion transport
LEO79_05055	COG0657	acetylesterase activity
LEO79_05065	COG0674	pyruvate-flavodoxin oxidoreductase activity
LEO79_05065	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LEO79_05065	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LEO79_05065	COG1013	pyruvate-flavodoxin oxidoreductase activity
LEO79_05075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LEO79_05090	COG1012	belongs to the aldehyde dehydrogenase family
LEO79_05100	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LEO79_05115	COG0180	Tryptophanyl-tRNA synthetase
LEO79_05120	COG0546	phosphoglycolate phosphatase activity
LEO79_05125	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LEO79_05130	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LEO79_05140	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LEO79_05145	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LEO79_05175	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LEO79_05180	COG0583	DNA-binding transcription factor activity
LEO79_05195	COG0583	DNA-binding transcription factor activity
LEO79_05210	COG3121	Chaperone
LEO79_05215	COG3188	usher protein
LEO79_05220	COG3121	Chaperone
LEO79_05230	COG0739	heme binding
LEO79_05240	COG3264	Mechanosensitive ion channel
LEO79_05240	COG1511	domain protein
LEO79_05245	COG0584	glycerophosphoryl diester phosphodiesterase
LEO79_05255	COG1053	succinate dehydrogenase
LEO79_05260	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LEO79_05265	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LEO79_05270	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LEO79_05285	COG3214	Protein conserved in bacteria
LEO79_05290	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LEO79_05310	COG0300	oxidoreductase activity
LEO79_05330	COG4067	protein conserved in archaea
LEO79_05330	COG0189	ligase activity
LEO79_05335	COG0516	GMP reductase activity
LEO79_05345	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LEO79_05350	COG2011	ABC-type metal ion transport system permease component
LEO79_05360	COG1464	Belongs to the NlpA lipoprotein family
LEO79_05375	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEO79_05385	COG2199	diguanylate cyclase activity
LEO79_05395	COG2199	diguanylate cyclase activity
LEO79_05400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LEO79_05415	COG1335	isochorismatase
LEO79_05420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LEO79_05425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LEO79_05430	COG1702	phosphate starvation-inducible protein PhoH
LEO79_05435	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LEO79_05440	COG4535	Mg2 and Co2 transporter CorC
LEO79_05445	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LEO79_05450	COG2888	peptidyl-tyrosine sulfation
LEO79_05455	COG0495	leucyl-tRNA aminoacylation
LEO79_05470	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LEO79_05475	COG0799	negative regulation of ribosome biogenesis
LEO79_05480	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LEO79_05485	COG0768	penicillin binding
LEO79_05490	COG0772	Belongs to the SEDS family
LEO79_05495	COG2951	lytic endotransglycosylase activity
LEO79_05500	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LEO79_05505	COG1686	Belongs to the peptidase S11 family
LEO79_05510	COG2921	Belongs to the UPF0250 family
LEO79_05515	COG0321	lipoyl(octanoyl) transferase activity
LEO79_05520	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LEO79_05575	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LEO79_05590	COG0789	Transcriptional regulator
LEO79_05595	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LEO79_05605	COG1970	mechanosensitive ion channel activity
LEO79_05610	COG4974	Belongs to the 'phage' integrase family
LEO79_05620	COG0312	modulator of DNA gyrase
LEO79_05625	COG0312	modulator of DNA gyrase
LEO79_05640	COG0826	peptidase U32
LEO79_05645	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LEO79_05655	COG1422	Protein of unknown function (DUF1090)
LEO79_05660	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LEO79_05665	COG2211	Major facilitator Superfamily
LEO79_05670	COG1185	polyribonucleotide nucleotidyltransferase activity
LEO79_05675	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LEO79_05680	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LEO79_05685	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LEO79_05690	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LEO79_05695	COG0195	Participates in both transcription termination and antitermination
LEO79_05700	COG0779	Required for maturation of 30S ribosomal subunits
LEO79_05715	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LEO79_05720	COG0149	triose-phosphate isomerase activity
LEO79_05725	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LEO79_05730	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LEO79_05740	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LEO79_05745	COG1534	Rna-binding protein
LEO79_05760	COG1360	Flagellar Motor Protein
LEO79_05765	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LEO79_05770	COG1722	exodeoxyribonuclease VII activity
LEO79_05775	COG0142	geranyltranstransferase activity
LEO79_05780	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LEO79_05785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEO79_05790	COG0601	transmembrane transport
LEO79_05800	COG4172	Belongs to the ABC transporter superfamily
LEO79_05805	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LEO79_05810	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LEO79_05815	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LEO79_05820	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LEO79_05835	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LEO79_05835	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LEO79_05840	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LEO79_05850	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LEO79_05860	COG3381	protein complex oligomerization
LEO79_05875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LEO79_05880	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LEO79_05885	COG0511	ligase activity, forming carbon-carbon bonds
LEO79_05890	COG0439	Biotin carboxylase
LEO79_05895	COG3924	membrane
LEO79_05900	COG4145	pantothenate transmembrane transporter activity
LEO79_05905	COG2190	(PTS) system
LEO79_05905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LEO79_05905	COG1263	PTS System
LEO79_05910	COG0583	DNA-binding transcription factor activity
LEO79_05915	COG0604	alcohol dehydrogenase
LEO79_05920	COG2264	protein methyltransferase activity
LEO79_05940	COG0778	Nitroreductase
LEO79_05945	COG1902	pentaerythritol trinitrate reductase activity
LEO79_05945	COG0446	pyridine nucleotide-disulphide oxidoreductase
LEO79_05950	COG0616	signal peptide processing
LEO79_05970	COG3139	Protein of unknown function (DUF1315)
LEO79_05975	COG0252	asparaginase activity
LEO79_05980	COG0786	glutamate:sodium symporter activity
LEO79_05995	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LEO79_06000	COG0384	phenazine biosynthesis protein PhzF
LEO79_06010	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LEO79_06015	COG0175	sulfate reduction
LEO79_06020	COG2113	Glycine betaine
LEO79_06025	COG4176	ABC-type proline glycine betaine transport system permease component
LEO79_06030	COG4175	Glycine betaine
LEO79_06045	COG2966	Psort location CytoplasmicMembrane, score
LEO79_06055	COG0521	Mo-molybdopterin cofactor biosynthetic process
LEO79_06075	COG2313	pseudouridylate synthase activity
LEO79_06080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LEO79_06085	COG2146	nitrite reductase [NAD(P)H] activity
LEO79_06085	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LEO79_06090	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LEO79_06090	COG2146	nitrite reductase [NAD(P)H] activity
LEO79_06095	COG1116	anion transmembrane transporter activity
LEO79_06100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LEO79_06105	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LEO79_06105	COG1116	anion transmembrane transporter activity
LEO79_06115	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LEO79_06115	COG1648	precorrin-2 dehydrogenase activity
LEO79_06120	COG0243	molybdopterin cofactor binding
LEO79_06145	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LEO79_06160	COG1073	alpha beta
LEO79_06165	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
LEO79_06170	COG2195	Cleaves the N-terminal amino acid of tripeptides
LEO79_06175	COG4608	Belongs to the ABC transporter superfamily
LEO79_06180	COG0444	Belongs to the ABC transporter superfamily
LEO79_06190	COG4239	(ABC) transporter, permease
LEO79_06195	COG4174	ABC transporter (Permease)
LEO79_06200	COG4206	TonB-dependent receptor
LEO79_06210	COG0811	peptide transport
LEO79_06215	COG0811	peptide transport
LEO79_06220	COG0848	biopolymer transport protein
LEO79_06270	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LEO79_06275	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LEO79_06280	COG0840	transmembrane signaling receptor activity
LEO79_06290	COG1278	Cold shock
LEO79_06330	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LEO79_06340	COG0688	phosphatidylethanolamine metabolic process
LEO79_06345	COG4628	conserved protein (DUF2132)
LEO79_06365	COG3300	MHYT domain
LEO79_06365	COG5001	Diguanylate cyclase
LEO79_06370	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
LEO79_06395	COG1132	(ABC) transporter
LEO79_06405	COG2897	thiosulfate sulfurtransferase activity
LEO79_06410	COG2066	Belongs to the glutaminase family
LEO79_06415	COG3171	Protein conserved in bacteria
LEO79_06420	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LEO79_06425	COG2234	aminopeptidase activity
LEO79_06425	COG4935	Belongs to the peptidase S8 family
LEO79_06430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LEO79_06435	COG2200	EAL domain
LEO79_06440	COG1090	epimerase
LEO79_06445	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LEO79_06450	COG4181	ATPase activity
LEO79_06455	COG2755	lipolytic protein G-D-S-L family
LEO79_06460	COG0784	Response regulator, receiver
LEO79_06460	COG0835	chemotaxis
LEO79_06470	COG0517	IMP dehydrogenase activity
LEO79_06470	COG0516	GMP reductase activity
LEO79_06475	COG0488	(ABC) transporter
LEO79_06485	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LEO79_06525	COG0789	Transcriptional regulator
LEO79_06540	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LEO79_06550	COG0668	transmembrane transport
LEO79_06560	COG2731	YhcH YjgK YiaL family protein
LEO79_06570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LEO79_06575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LEO79_06580	COG3227	Zinc metalloprotease (Elastase)
LEO79_06585	COG0583	DNA-binding transcription factor activity
LEO79_06590	COG0477	Major facilitator Superfamily
LEO79_06600	COG0569	domain protein
LEO79_06600	COG2985	domain, Protein
LEO79_06605	COG1272	protein, Hemolysin III
LEO79_06610	COG0076	glutamate decarboxylase activity
LEO79_06615	COG2917	probably involved in intracellular septation
LEO79_06620	COG2350	Protein conserved in bacteria
LEO79_06630	COG1555	photosystem II stabilization
LEO79_06635	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LEO79_06640	COG3104	oligopeptide transport
LEO79_06645	COG0745	RESPONSE REGULATOR receiver
LEO79_06675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LEO79_06690	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LEO79_06695	COG1280	lysine exporter protein (LysE YggA)
LEO79_06725	COG0316	Belongs to the HesB IscA family
LEO79_06735	COG0038	chloride channel
LEO79_06740	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LEO79_06755	COG0671	phosphoesterase, PA-phosphatase related
LEO79_06765	COG0583	DNA-binding transcription factor activity
LEO79_06770	COG2076	Multidrug Resistance protein
LEO79_06780	COG0346	lactoylglutathione lyase activity
LEO79_06785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LEO79_06790	COG1643	Atp-dependent helicase
LEO79_06800	COG1489	DNA binding
LEO79_06805	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LEO79_06810	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LEO79_06820	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LEO79_06825	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LEO79_06830	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LEO79_06840	COG0842	Transport permease protein
LEO79_06845	COG1131	(ABC) transporter
LEO79_06860	COG0163	prenyltransferase activity
LEO79_06865	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LEO79_06870	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LEO79_06885	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
LEO79_06900	COG1136	(ABC) transporter
LEO79_06955	COG0529	Catalyzes the synthesis of activated sulfate
LEO79_06960	COG0471	metal ion transport
LEO79_06960	COG3273	potassium ion transport
LEO79_06965	COG2895	sulfate adenylyltransferase (ATP) activity
LEO79_06970	COG0175	sulfate reduction
LEO79_06975	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LEO79_06975	COG1648	precorrin-2 dehydrogenase activity
LEO79_06980	COG0330	HflC and HflK could
LEO79_06985	COG1585	Membrane protein implicated in regulation of membrane protease activity
LEO79_06995	COG0673	inositol 2-dehydrogenase activity
LEO79_07005	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LEO79_07010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LEO79_07015	COG3036	rescue of stalled ribosome
LEO79_07020	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LEO79_07030	COG0138	bifunctional purine biosynthesis protein purh
LEO79_07065	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEO79_07070	COG0358	DNA primase activity
LEO79_07075	COG1610	YqeY-like protein
LEO79_07080	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LEO79_07085	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LEO79_07095	COG1388	LysM domain
LEO79_07095	COG4942	peptidase
LEO79_07100	COG1238	metal cluster binding
LEO79_07105	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LEO79_07110	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LEO79_07115	COG0585	pseudouridine synthase activity
LEO79_07120	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LEO79_07125	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LEO79_07130	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LEO79_07135	COG0148	phosphopyruvate hydratase activity
LEO79_07140	COG0504	CTP synthase activity
LEO79_07145	COG3956	TIGRFAM MazG family protein
LEO79_07150	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LEO79_07155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEO79_07165	COG4807	Protein conserved in bacteria
LEO79_07170	COG3023	N-Acetylmuramoyl-L-alanine amidase
LEO79_07175	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LEO79_07180	COG1381	Involved in DNA repair and RecF pathway recombination
LEO79_07190	COG0571	ribonuclease III activity
LEO79_07195	COG0681	Belongs to the peptidase S26 family
LEO79_07200	COG0481	GTPase activity
LEO79_07215	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
LEO79_07220	COG1595	DNA-templated transcription, initiation
LEO79_07225	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LEO79_07235	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LEO79_07240	COG0354	folic acid binding
LEO79_07245	COG0583	DNA-binding transcription factor activity
LEO79_07275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LEO79_07285	COG0126	phosphoglycerate kinase activity
LEO79_07290	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LEO79_07295	COG1940	carbohydrate kinase activity
LEO79_07300	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LEO79_07310	COG4991	sh3 domain protein
LEO79_07315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LEO79_07330	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LEO79_07335	COG1028	Short-chain dehydrogenase reductase Sdr
LEO79_07345	COG1505	serine-type exopeptidase activity
LEO79_07350	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LEO79_07355	COG0765	amino acid transport
LEO79_07360	COG0765	amino acid transport
LEO79_07365	COG1126	abc transporter atp-binding protein
LEO79_07370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LEO79_07375	COG3174	membrane
LEO79_07380	COG0110	maltose O-acetyltransferase activity
LEO79_07410	COG1942	4-Oxalocrotonate Tautomerase
LEO79_07420	COG0583	DNA-binding transcription factor activity
LEO79_07425	COG0165	Argininosuccinate lyase
LEO79_07430	COG0137	argininosuccinate synthase activity
LEO79_07440	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LEO79_07445	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LEO79_07455	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LEO79_07465	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LEO79_07500	COG0583	DNA-binding transcription factor activity
LEO79_07505	COG1380	Effector of murein hydrolase LrgA
LEO79_07510	COG1346	cytolysis
LEO79_07515	COG0527	aspartate kinase activity
LEO79_07515	COG0460	homoserine dehydrogenase
LEO79_07520	COG0626	cystathionine gamma-synthase activity
LEO79_07535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LEO79_07540	COG0814	amino acid
LEO79_07545	COG1218	3'(2'),5'-bisphosphate nucleotidase
LEO79_07550	COG0494	nUDIX hydrolase
LEO79_07555	COG1011	Hydrolase
LEO79_07560	COG1902	pentaerythritol trinitrate reductase activity
LEO79_07570	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LEO79_07585	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
LEO79_07595	COG3156	type II secretion system protein K
LEO79_07610	COG4795	General secretion pathway protein
LEO79_07615	COG2165	general secretion pathway protein
LEO79_07625	COG2165	general secretion pathway protein
LEO79_07630	COG1459	type II secretion system
LEO79_07635	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LEO79_07645	COG3031	protein transport across the cell outer membrane
LEO79_07655	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LEO79_07660	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LEO79_07675	COG0456	acetyltransferase
LEO79_07680	COG3133	Outer membrane lipoprotein
LEO79_07685	COG3025	triphosphatase activity
LEO79_07690	COG1392	Phosphate transport regulator
LEO79_07695	COG0306	phosphate transporter
LEO79_07700	COG0617	tRNA 3'-terminal CCA addition
LEO79_07705	COG3267	Type II secretory pathway component ExeA
LEO79_07705	COG3409	Peptidoglycan-binding domain 1 protein
LEO79_07715	COG1194	a g-specific adenine glycosylase
LEO79_07720	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
LEO79_07735	COG3240	lipase activity
LEO79_07745	COG3009	Protein conserved in bacteria
LEO79_07750	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LEO79_07750	COG3008	intermembrane lipid transfer
LEO79_07755	COG2995	paraquat-inducible protein a
LEO79_07765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LEO79_07770	COG2203	Gaf domain
LEO79_07770	COG3706	GGDEF domain
LEO79_07770	COG4251	negative regulation of phosphorylation
LEO79_07770	COG5001	Diguanylate cyclase
LEO79_07775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LEO79_07780	COG2813	Specifically methylates the guanine in position
LEO79_07785	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LEO79_07790	COG0297	glycogen (starch) synthase activity
LEO79_07830	COG1757	Na H antiporter
LEO79_07835	COG0583	DNA-binding transcription factor activity
LEO79_07840	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LEO79_07845	COG3842	ATPase activity
LEO79_07850	COG1176	ABC-type spermidine putrescine transport system, permease component I
LEO79_07855	COG1177	transmembrane transport
LEO79_07860	COG1012	belongs to the aldehyde dehydrogenase family
LEO79_07865	COG0109	protoheme IX farnesyltransferase activity
LEO79_07895	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
LEO79_07905	COG1565	acr, cog1565
LEO79_07905	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LEO79_07910	COG1444	tRNA N-acetyltransferase activity
LEO79_07930	COG1803	Methylglyoxal synthase
LEO79_07945	COG0252	asparaginase activity
LEO79_07965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LEO79_07965	COG1263	PTS System
LEO79_07970	COG0366	Alpha amylase catalytic
LEO79_07975	COG0110	maltose O-acetyltransferase activity
LEO79_07980	COG1522	sequence-specific DNA binding
LEO79_08010	COG3068	Protein conserved in bacteria
LEO79_08020	COG0739	heme binding
LEO79_08040	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
LEO79_08045	COG1121	(ABC) transporter
LEO79_08050	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LEO79_08055	COG0583	DNA-binding transcription factor activity
LEO79_08065	COG1573	uracil-dna glycosylase
LEO79_08070	COG2962	Rard protein
LEO79_08075	COG2827	Endonuclease containing a URI domain
LEO79_08090	COG1842	Phage shock protein A
LEO79_08095	COG0204	Acyl-transferase
LEO79_08115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LEO79_08125	COG0484	heat shock protein binding
LEO79_08175	COG1289	transmembrane transporter activity
LEO79_08180	COG1566	PFAM secretion protein HlyD family protein
LEO79_08195	COG1051	belongs to the nudix hydrolase family
LEO79_08200	COG3150	esterase
LEO79_08210	COG3151	Protein conserved in bacteria
LEO79_08215	COG0494	nUDIX hydrolase
LEO79_08220	COG1538	Outer membrane efflux protein
LEO79_08225	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LEO79_08225	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LEO79_08230	COG1560	Kdo2-lipid A biosynthetic process
LEO79_08245	COG2771	luxR family
LEO79_08250	COG3916	Acyl-homoserine-lactone synthase
LEO79_08260	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
LEO79_08265	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LEO79_08265	COG2213	PTS system mannitol-specific
LEO79_08270	COG0246	Mannitol dehydrogenase
LEO79_08275	COG3722	fumarate hydratase activity
LEO79_08280	COG3263	regulation of cellular component size
LEO79_08300	COG1671	Belongs to the UPF0178 family
LEO79_08315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LEO79_08320	COG0513	Belongs to the DEAD box helicase family
LEO79_08340	COG1575	Belongs to the MenA family. Type 1 subfamily
LEO79_08345	COG1169	isochorismate synthase
LEO79_08350	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LEO79_08355	COG0596	Alpha beta hydrolase
LEO79_08360	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LEO79_08370	COG0318	PFAM AMP-dependent synthetase and ligase
LEO79_08375	COG3291	Pkd domain containing protein
LEO79_08380	COG2949	membrane
LEO79_08385	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LEO79_08395	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LEO79_08425	COG2873	o-acetylhomoserine
LEO79_08435	COG1979	alcohol dehydrogenase
LEO79_08450	COG4221	oxidoreductase activity
LEO79_08470	COG1285	pathogenesis
LEO79_08485	COG1368	sulfuric ester hydrolase activity
LEO79_08490	COG1522	sequence-specific DNA binding
LEO79_08500	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LEO79_08510	COG1058	Belongs to the CinA family
LEO79_08510	COG1546	Belongs to the CinA family
LEO79_08515	COG1988	membrane-bound metal-dependent
LEO79_08525	COG0561	phosphatase activity
LEO79_08530	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LEO79_08540	COG1011	Hydrolase
LEO79_08555	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LEO79_08560	COG0019	diaminopimelate decarboxylase activity
LEO79_08570	COG1965	Belongs to the frataxin family
LEO79_08575	COG0400	carboxylic ester hydrolase activity
LEO79_08580	COG3072	Adenylate cyclase
LEO79_08585	COG0181	hydroxymethylbilane synthase activity
LEO79_08595	COG2959	enzyme of heme biosynthesis
LEO79_08600	COG3071	HemY protein
LEO79_08610	COG0312	modulator of DNA gyrase
LEO79_08615	COG3028	Belongs to the UPF0307 family
LEO79_08625	COG2926	Belongs to the UPF0265 family
LEO79_08660	COG1396	sequence-specific DNA binding
LEO79_08665	COG3135	benzoate transporter
LEO79_08695	COG3047	cAMP biosynthetic process
LEO79_08700	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LEO79_08705	COG2197	response regulator
LEO79_08725	COG1278	Cold shock
LEO79_08755	COG3706	GGDEF domain
LEO79_08760	COG0347	Belongs to the P(II) protein family
LEO79_08765	COG0004	ammonium transporteR
LEO79_08775	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LEO79_08780	COG1074	ATP-dependent DNA helicase activity
LEO79_08785	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LEO79_08790	COG2259	Doxx family
LEO79_08795	COG1741	Belongs to the pirin family
LEO79_08805	COG0583	DNA-binding transcription factor activity
LEO79_08830	COG1175	transmembrane transport
LEO79_08840	COG3842	ATPase activity
LEO79_08870	COG0456	acetyltransferase
LEO79_08875	COG0753	catalase activity
LEO79_08895	COG0494	nUDIX hydrolase
LEO79_08900	COG0628	permease
LEO79_08910	COG2957	Belongs to the agmatine deiminase family
LEO79_08925	COG2957	Belongs to the agmatine deiminase family
LEO79_08930	COG0583	DNA-binding transcription factor activity
LEO79_08945	COG1461	Dihydroxyacetone kinase
LEO79_08950	COG2376	Dihydroxyacetone kinase
LEO79_08955	COG2252	PERMEase
LEO79_08960	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LEO79_08995	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LEO79_09000	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LEO79_09005	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LEO79_09010	COG0049	tRNA binding
LEO79_09015	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LEO79_09020	COG2168	tRNA wobble position uridine thiolation
LEO79_09030	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LEO79_09035	COG0251	oxidation-reduction process
LEO79_09040	COG2964	Protein conserved in bacteria
LEO79_09045	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEO79_09050	COG0085	RNA polymerase activity
LEO79_09055	COG0222	ribosome binding
LEO79_09060	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LEO79_09065	COG0081	regulation of translation
LEO79_09070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LEO79_09075	COG0250	Participates in transcription elongation, termination and antitermination
LEO79_09090	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LEO79_09115	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LEO79_09120	COG0569	domain protein
LEO79_09125	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LEO79_09130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LEO79_09135	COG3005	denitrification pathway
LEO79_09140	COG0243	molybdopterin cofactor binding
LEO79_09175	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LEO79_09185	COG2204	response regulator
LEO79_09195	COG2205	protein histidine kinase activity
LEO79_09215	COG0516	GMP reductase activity
LEO79_09215	COG0517	IMP dehydrogenase activity
LEO79_09225	COG1522	sequence-specific DNA binding
LEO79_09230	COG2502	aspartate--ammonia ligase
LEO79_09235	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LEO79_09240	COG0542	response to heat
LEO79_09250	COG0564	pseudouridine synthase activity
LEO79_09255	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LEO79_09260	COG3681	Belongs to the UPF0597 family
LEO79_09265	COG2964	Protein conserved in bacteria
LEO79_09270	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LEO79_09275	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LEO79_09280	COG1979	alcohol dehydrogenase
LEO79_09285	COG2207	Transcriptional regulator
LEO79_09290	COG3040	lipid binding
LEO79_09325	COG0540	Belongs to the ATCase OTCase family
LEO79_09330	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
LEO79_09335	COG1438	arginine binding
LEO79_09340	COG1288	antiporter activity
LEO79_09345	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LEO79_09385	COG3250	beta-galactosidase activity
LEO79_09390	COG1609	Transcriptional regulator
LEO79_09395	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LEO79_09405	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LEO79_09410	COG2017	converts alpha-aldose to the beta-anomer
LEO79_09415	COG0667	Aldo Keto reductase
LEO79_09420	COG1968	undecaprenyl-diphosphatase activity
LEO79_09425	COG3806	Anti-sigma factor
LEO79_09430	COG1595	DNA-templated transcription, initiation
LEO79_09450	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LEO79_09455	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LEO79_09475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LEO79_09480	COG1131	(ABC) transporter
LEO79_09485	COG0842	Transport permease protein
LEO79_09490	COG0842	Transport permease protein
LEO79_09495	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LEO79_09505	COG2116	formate transmembrane transporter activity
LEO79_09510	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LEO79_09510	COG1648	precorrin-2 dehydrogenase activity
LEO79_09515	COG2239	Acts as a magnesium transporter
LEO79_09520	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LEO79_09525	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LEO79_09535	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LEO79_09545	COG0514	ATP-dependent DNA helicase (RecQ)
LEO79_09550	COG2050	protein possibly involved in aromatic compounds catabolism
LEO79_09565	COG2258	MOSC domain
LEO79_09570	COG1177	transmembrane transport
LEO79_09575	COG1176	ABC-type spermidine putrescine transport system, permease component I
LEO79_09580	COG3842	ATPase activity
LEO79_09600	COG0174	glutamine synthetase
LEO79_09620	COG3045	CreA protein
LEO79_09625	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEO79_09630	COG0443	Heat shock 70 kDa protein
LEO79_09645	COG0366	Alpha amylase catalytic
LEO79_09660	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEO79_09665	COG0745	RESPONSE REGULATOR receiver
LEO79_09675	COG2205	protein histidine kinase activity
LEO79_09685	COG0281	malic enzyme
LEO79_09690	COG0702	epimerase
LEO79_09695	COG0254	rRNA binding
LEO79_09700	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LEO79_09725	COG0129	dihydroxy-acid dehydratase activity
LEO79_09735	COG3978	acetolactate synthase activity
LEO79_09745	COG0606	chelatase, subunit chli
LEO79_09750	COG0204	Acyl-transferase
LEO79_09755	COG0204	Acyl-transferase
LEO79_09760	COG1683	Conserved Protein
LEO79_09770	COG1335	isochorismatase
LEO79_09780	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LEO79_09785	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LEO79_09795	COG3084	Protein conserved in bacteria
LEO79_09800	COG2203	Gaf domain
LEO79_09800	COG3706	GGDEF domain
LEO79_09800	COG4251	negative regulation of phosphorylation
LEO79_09800	COG5001	Diguanylate cyclase
LEO79_09815	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LEO79_09820	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LEO79_09825	COG1561	YicC-like family, N-terminal region
LEO79_09835	COG1519	Transferase
LEO79_09840	COG0859	PFAM glycosyl transferase family 9
LEO79_09845	COG0463	Glycosyl transferase, family 2
LEO79_09850	COG0859	PFAM glycosyl transferase family 9
LEO79_09855	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LEO79_09860	COG2990	Protein conserved in bacteria
LEO79_09865	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LEO79_09875	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LEO79_09880	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LEO79_09885	COG2003	Belongs to the UPF0758 family
LEO79_09890	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LEO79_09895	COG0756	dUTP diphosphatase activity
LEO79_09900	COG1309	transcriptional regulator
LEO79_09920	COG0668	transmembrane transport
LEO79_09930	COG0166	Belongs to the GPI family
LEO79_09935	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LEO79_09940	COG0583	DNA-binding transcription factor activity
LEO79_09950	COG0045	succinate-CoA ligase (ADP-forming) activity
LEO79_09950	COG1042	CoA-binding domain protein
LEO79_09950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LEO79_09975	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
LEO79_09980	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LEO79_09985	COG1739	Uncharacterized protein family UPF0029
LEO79_09990	COG0006	proline dipeptidase activity
LEO79_09995	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LEO79_10000	COG1250	3-hydroxyacyl-CoA dehydrogenase
LEO79_10000	COG1024	Enoyl-CoA hydratase
LEO79_10005	COG0183	Belongs to the thiolase family
LEO79_10035	COG0425	Belongs to the sulfur carrier protein TusA family
LEO79_10040	COG0251	oxidation-reduction process
LEO79_10060	COG2885	chlorophyll binding
LEO79_10070	COG1335	isochorismatase
LEO79_10075	COG2818	Glycosylase
LEO79_10080	COG0752	glycyl-tRNA synthetase alpha subunit
LEO79_10085	COG0751	glycine-tRNA ligase activity
LEO79_10095	COG3706	GGDEF domain
LEO79_10095	COG5001	Diguanylate cyclase
LEO79_10095	COG4251	negative regulation of phosphorylation
LEO79_10095	COG2203	Gaf domain
LEO79_10110	COG0814	amino acid
LEO79_10115	COG0814	amino acid
LEO79_10120	COG3033	Beta-eliminating lyase
LEO79_10130	COG0348	domain, Protein
LEO79_10140	COG0446	pyridine nucleotide-disulphide oxidoreductase
LEO79_10145	COG1773	rubredoxin
LEO79_10145	COG0426	domain, Protein
LEO79_10150	COG3604	Transcriptional regulator
LEO79_10155	COG1609	Transcriptional regulator
LEO79_10195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LEO79_10210	COG2960	long-chain fatty acid transporting porin activity
LEO79_10220	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LEO79_10235	COG3118	belongs to the thioredoxin family
LEO79_10240	COG0513	Belongs to the DEAD box helicase family
LEO79_10245	COG0248	Ppx GppA phosphatase
LEO79_10255	COG0742	ribosomal rna small subunit methyltransferase
LEO79_10275	COG0084	hydrolase, TatD family'
LEO79_10280	COG0805	protein transport
LEO79_10285	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LEO79_10290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LEO79_10295	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LEO79_10300	COG3165	ubiquinone biosynthetic process from chorismate
LEO79_10310	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LEO79_10315	COG0402	S-adenosylhomocysteine deaminase activity
LEO79_10350	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LEO79_10355	COG0848	biopolymer transport protein
LEO79_10360	COG0811	peptide transport
LEO79_10365	COG0811	peptide transport
LEO79_10375	COG2771	luxR family
LEO79_10380	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LEO79_10385	COG1349	DNA-binding transcription factor activity
LEO79_10390	COG0745	RESPONSE REGULATOR receiver
LEO79_10395	COG2205	protein histidine kinase activity
LEO79_10405	COG4452	Inner membrane protein CreD
LEO79_10410	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LEO79_10415	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LEO79_10420	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LEO79_10425	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LEO79_10430	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LEO79_10435	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LEO79_10440	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LEO79_10450	COG0356	it plays a direct role in the translocation of protons across the membrane
LEO79_10460	COG1475	DNA binding
LEO79_10465	COG1192	Involved in chromosome partitioning
LEO79_10470	COG0357	Ribosomal RNA small subunit methyltransferase G
LEO79_10475	COG0445	tRNA wobble uridine modification
LEO79_10480	COG0716	FMN binding
LEO79_10485	COG4774	siderophore transport
LEO79_10490	COG4615	Cyclic peptide transporter
LEO79_10495	COG1120	ATPase activity
LEO79_10500	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LEO79_10510	COG3550	peptidyl-serine autophosphorylation
LEO79_10560	COG1695	Transcriptional regulator
LEO79_10585	COG3173	Aminoglycoside phosphotransferase
LEO79_10730	COG4974	Belongs to the 'phage' integrase family
LEO79_10735	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LEO79_10740	COG0706	membrane insertase activity
LEO79_10745	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LEO79_10750	COG0594	ribonuclease P activity
LEO79_10755	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LEO79_10760	COG1126	abc transporter atp-binding protein
LEO79_10775	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LEO79_10780	COG0592	DNA-directed DNA polymerase activity
LEO79_10790	COG0187	DNA topoisomerase II activity
LEO79_10795	COG2207	Transcriptional regulator
LEO79_10800	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LEO79_10805	COG0071	Belongs to the small heat shock protein (HSP20) family
LEO79_10810	COG0071	Belongs to the small heat shock protein (HSP20) family
LEO79_10815	COG3977	Valine--pyruvate aminotransferase
LEO79_10830	COG2814	Major facilitator Superfamily
LEO79_10835	COG0745	RESPONSE REGULATOR receiver
LEO79_10840	COG2205	protein histidine kinase activity
LEO79_10860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LEO79_10865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LEO79_10865	COG4191	Histidine kinase
LEO79_10870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LEO79_10875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LEO79_10880	COG1309	transcriptional regulator
LEO79_10910	COG0561	phosphatase activity
LEO79_10915	COG2267	carboxylic ester hydrolase activity
LEO79_10925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LEO79_10930	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LEO79_10935	COG1758	RNA polymerase activity
LEO79_10945	COG0859	PFAM glycosyl transferase family 9
LEO79_10950	COG3642	lipopolysaccharide core region biosynthetic process
LEO79_10990	COG0589	response to stress
LEO79_10995	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LEO79_11000	COG3706	GGDEF domain
LEO79_11005	COG1528	Iron-storage protein
LEO79_11010	COG2081	HI0933 family
LEO79_11015	COG2223	nitrite transmembrane transporter activity
LEO79_11020	COG1280	lysine exporter protein (LysE YggA)
LEO79_11035	COG3188	usher protein
LEO79_11055	COG2205	protein histidine kinase activity
LEO79_11055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LEO79_11065	COG3275	phosphorelay sensor kinase activity
LEO79_11070	COG3279	Response regulator of the LytR AlgR family
LEO79_11075	COG2223	nitrite transmembrane transporter activity
LEO79_11080	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LEO79_11085	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LEO79_11135	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LEO79_11140	COG2166	iron-sulfur cluster assembly
LEO79_11145	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LEO79_11165	COG1063	alcohol dehydrogenase
LEO79_11170	COG0156	8-amino-7-oxononanoate synthase activity
LEO79_11180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LEO79_11225	COG1609	Transcriptional regulator
LEO79_11240	COG1580	Controls the rotational direction of flagella during chemotaxis
LEO79_11245	COG3161	chorismate lyase activity
LEO79_11250	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LEO79_11255	COG2937	Belongs to the GPAT DAPAT family
LEO79_11260	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LEO79_11275	COG0534	Mate efflux family protein
LEO79_11280	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LEO79_11285	COG2205	protein histidine kinase activity
LEO79_11290	COG0745	RESPONSE REGULATOR receiver
LEO79_11300	COG1045	serine acetyltransferase
LEO79_11310	COG3074	FtsZ-dependent cytokinesis
LEO79_11315	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
LEO79_11320	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LEO79_11320	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LEO79_11325	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LEO79_11365	COG1609	Transcriptional regulator
LEO79_11370	COG3250	beta-galactosidase activity
LEO79_11375	COG2731	YhcH YjgK YiaL family protein
LEO79_11380	COG0531	amino acid
LEO79_11385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LEO79_11390	COG0531	amino acid
LEO79_11395	COG0385	Bile acid
LEO79_11400	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LEO79_11425	COG0583	DNA-binding transcription factor activity
LEO79_11430	COG1079	Belongs to the binding-protein-dependent transport system permease family
LEO79_11435	COG4603	Belongs to the binding-protein-dependent transport system permease family
LEO79_11440	COG3845	ABC transporter
LEO79_11445	COG1744	ABC transporter substrate-binding protein PnrA-like
LEO79_11450	COG0210	DNA helicase
LEO79_11460	COG1943	Transposase
LEO79_11465	COG0583	DNA-binding transcription factor activity
LEO79_11505	COG1280	lysine exporter protein (LysE YggA)
LEO79_11515	COG2962	Rard protein
LEO79_11525	COG1012	belongs to the aldehyde dehydrogenase family
LEO79_11530	COG1396	sequence-specific DNA binding
LEO79_11535	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LEO79_11545	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LEO79_11545	COG0519	Catalyzes the synthesis of GMP from XMP
LEO79_11555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LEO79_11580	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LEO79_11585	COG0569	domain protein
LEO79_11590	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LEO79_11590	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LEO79_11595	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LEO79_11600	COG0242	peptide deformylase activity
LEO79_11610	COG0758	DNA mediated transformation
LEO79_11615	COG2922	Belongs to the Smg family
LEO79_11620	COG0551	DNA topoisomerase type I activity
LEO79_11625	COG0009	L-threonylcarbamoyladenylate synthase
LEO79_11630	COG0408	coproporphyrinogen oxidase activity
LEO79_11635	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LEO79_11640	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LEO79_11650	COG3078	GTPase activator activity
LEO79_11660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LEO79_11665	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LEO79_11675	COG3852	Histidine kinase
LEO79_11685	COG0174	glutamine synthetase
LEO79_11690	COG1217	gtp-binding protein TYPA
LEO79_11695	COG1295	ribonuclease BN
LEO79_11700	COG1490	D-aminoacyl-tRNA deacylase activity
LEO79_11710	COG0456	acetyltransferase
LEO79_11720	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LEO79_11725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LEO79_11730	COG2610	gluconate transmembrane transporter activity
LEO79_11735	COG3265	gluconokinase activity
LEO79_11740	COG0129	dihydroxy-acid dehydratase activity
LEO79_11745	COG0800	Aldolase
LEO79_11760	COG1609	Transcriptional regulator
LEO79_11770	COG4942	peptidase
LEO79_11775	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LEO79_11780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LEO79_11785	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LEO79_11790	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LEO79_11795	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LEO79_11795	COG0316	Belongs to the HesB IscA family
LEO79_11800	COG1040	competence protein
LEO79_11805	COG0596	Alpha beta hydrolase
LEO79_11820	COG2183	response to ionizing radiation
LEO79_11825	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LEO79_11835	COG2205	protein histidine kinase activity
LEO79_11845	COG0051	transcription antitermination factor activity, RNA binding
LEO79_11850	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LEO79_11855	COG0088	Forms part of the polypeptide exit tunnel
LEO79_11860	COG0089	rRNA binding
LEO79_11865	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LEO79_11870	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LEO79_11875	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LEO79_11880	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LEO79_11885	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LEO79_11890	COG0255	Belongs to the universal ribosomal protein uL29 family
LEO79_11895	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LEO79_11900	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LEO79_11905	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LEO79_11910	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LEO79_11915	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LEO79_11920	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LEO79_11925	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LEO79_11930	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LEO79_11935	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LEO79_11940	COG1841	ribosomal large subunit assembly
LEO79_11945	COG0200	Binds to the 23S rRNA
LEO79_11950	COG0201	protein transport
LEO79_11955	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LEO79_11960	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LEO79_11965	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LEO79_11970	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LEO79_11975	COG0202	RNA polymerase activity
LEO79_11980	COG0203	ribosomal protein L17
LEO79_12030	COG2249	NAD(P)H dehydrogenase (quinone) activity
LEO79_12035	COG0583	DNA-binding transcription factor activity
LEO79_12040	COG4221	oxidoreductase activity
LEO79_12055	COG1770	oligopeptidase
LEO79_12060	COG2358	TRAP transporter, solute receptor (TAXI family
LEO79_12075	COG3714	YhhN family
LEO79_12090	COG0583	DNA-binding transcription factor activity
LEO79_12100	COG1301	dicarboxylic acid transport
LEO79_12110	COG2095	MarC family integral membrane protein
LEO79_12120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LEO79_12130	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LEO79_12140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LEO79_12165	COG0742	ribosomal rna small subunit methyltransferase
LEO79_12170	COG0552	protein localization to endoplasmic reticulum
LEO79_12175	COG2884	Cell division ATP-binding protein ftsE
LEO79_12180	COG2177	Part of the ABC transporter FtsEX involved in
LEO79_12190	COG0288	reversible hydration of carbon dioxide
LEO79_12195	COG2188	Transcriptional regulator
LEO79_12200	COG1228	amidohydrolase
LEO79_12205	COG0010	Belongs to the arginase family
LEO79_12210	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LEO79_12215	COG2986	histidine ammonia-lyase
LEO79_12220	COG0387	Pfam Sodium calcium exchanger
LEO79_12225	COG2200	EAL domain
LEO79_12275	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LEO79_12280	COG1459	type II secretion system
LEO79_12295	COG2165	general secretion pathway protein
LEO79_12325	COG1077	Cell shape determining protein MreB Mrl
LEO79_12330	COG1792	Involved in formation and maintenance of cell shape
LEO79_12335	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LEO79_12340	COG0424	maF-like protein
LEO79_12345	COG1530	ribonuclease E activity
LEO79_12350	COG3164	Protein of unknown function
LEO79_12355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LEO79_12360	COG0312	modulator of DNA gyrase
LEO79_12375	COG0477	Major facilitator Superfamily
LEO79_12385	COG3437	response regulator, receiver
LEO79_12390	COG0784	Response regulator, receiver
LEO79_12390	COG2205	protein histidine kinase activity
LEO79_12390	COG5002	protein histidine kinase activity
LEO79_12395	COG2172	sigma factor antagonist activity
LEO79_12400	COG1366	Belongs to the anti-sigma-factor antagonist family
LEO79_12410	COG3700	Belongs to the class B bacterial acid phosphatase family
LEO79_12415	COG2321	neutral zinc metallopeptidase
LEO79_12450	COG0189	ligase activity
LEO79_12455	COG0642	Histidine kinase
LEO79_12460	COG0745	RESPONSE REGULATOR receiver
LEO79_12475	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LEO79_12480	COG0352	thiamine-phosphate diphosphorylase activity
LEO79_12485	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LEO79_12495	COG2022	thiamine diphosphate biosynthetic process
LEO79_12500	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LEO79_12540	COG3932	Exopolysaccharide synthesis, ExoD
LEO79_12560	COG1733	regulation of RNA biosynthetic process
LEO79_12585	COG2226	methyltransferase
LEO79_12595	COG1494	fructose-1,6-bisphosphatase
LEO79_12605	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LEO79_12610	COG5007	Belongs to the BolA IbaG family
LEO79_12620	COG2854	intermembrane phospholipid transfer
LEO79_12625	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LEO79_12630	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LEO79_12635	COG1127	ABC transporter
LEO79_12640	COG0517	IMP dehydrogenase activity
LEO79_12640	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LEO79_12645	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LEO79_12655	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LEO79_12660	COG1137	ATPase activity
LEO79_12665	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LEO79_12675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LEO79_12680	COG1660	Displays ATPase and GTPase activities
LEO79_12685	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LEO79_12705	COG3964	amidohydrolase
LEO79_12735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LEO79_12740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LEO79_12750	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LEO79_12755	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LEO79_12760	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LEO79_12765	COG0723	plastoquinol--plastocyanin reductase activity
LEO79_12770	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LEO79_12775	COG2857	Cytochrome c1
LEO79_12780	COG0625	glutathione transferase activity
LEO79_12785	COG2969	positive regulation of protein catabolic process
LEO79_12790	COG2823	Periplasmic or secreted lipoprotein
LEO79_12795	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LEO79_12800	COG0792	nuclease activity
LEO79_12805	COG3107	peptidoglycan biosynthetic process
LEO79_12810	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LEO79_12820	COG2001	Belongs to the MraZ family
LEO79_12825	COG0275	rRNA processing
LEO79_12830	COG3116	cell division
LEO79_12835	COG0768	penicillin binding
LEO79_12840	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LEO79_12845	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LEO79_12850	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LEO79_12855	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LEO79_12860	COG0772	Belongs to the SEDS family
LEO79_12865	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LEO79_12870	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LEO79_12875	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LEO79_12880	COG0849	cell division
LEO79_12885	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LEO79_12890	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LEO79_12900	COG0653	protein targeting
LEO79_12910	COG0494	nUDIX hydrolase
LEO79_12915	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LEO79_12920	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
LEO79_12935	COG1459	type II secretion system
LEO79_12940	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LEO79_12965	COG2186	Transcriptional regulator
LEO79_12970	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LEO79_12975	COG0508	dehydrogenase complex catalyzes the overall conversion of
LEO79_12980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LEO79_12990	COG0840	transmembrane signaling receptor activity
LEO79_12995	COG0840	transmembrane signaling receptor activity
LEO79_13000	COG1752	Esterase of the alpha-beta hydrolase superfamily
LEO79_13005	COG1049	propionate catabolic process, 2-methylcitrate cycle
LEO79_13010	COG2200	EAL domain
LEO79_13020	COG1280	lysine exporter protein (LysE YggA)
LEO79_13030	COG0523	cobalamin synthesis protein
LEO79_13035	COG0477	Major facilitator Superfamily
LEO79_13050	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LEO79_13055	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LEO79_13105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LEO79_13115	COG1546	Belongs to the CinA family
LEO79_13120	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LEO79_13125	COG2137	regulation of response to DNA damage stimulus
LEO79_13130	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LEO79_13135	COG0527	aspartate kinase activity
LEO79_13140	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LEO79_13175	COG1686	Belongs to the peptidase S11 family
LEO79_13180	COG0586	Pfam SNARE associated Golgi protein
LEO79_13185	COG1253	flavin adenine dinucleotide binding
LEO79_13190	COG0525	valine-tRNA ligase activity
LEO79_13195	COG2927	DNA polymerase III (CHI subunit)
LEO79_13200	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LEO79_13205	COG0795	lipopolysaccharide-transporting ATPase activity
LEO79_13210	COG0795	lipopolysaccharide-transporting ATPase activity
LEO79_13230	COG0004	ammonium transporteR
LEO79_13245	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEO79_13260	COG2165	general secretion pathway protein
LEO79_13265	COG0084	hydrolase, TatD family'
LEO79_13270	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LEO79_13280	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LEO79_13285	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LEO79_13290	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LEO79_13300	COG4520	surface antigen
LEO79_13305	COG3447	MASE1 domain protein
LEO79_13305	COG5002	protein histidine kinase activity
LEO79_13305	COG5001	Diguanylate cyclase
LEO79_13315	COG0560	Phosphoserine phosphatase
LEO79_13330	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LEO79_13340	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
LEO79_13345	COG0776	regulation of translation
LEO79_13360	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LEO79_13365	COG0735	belongs to the Fur family
LEO79_13385	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LEO79_13390	COG0513	Belongs to the DEAD box helicase family
LEO79_13395	COG3022	response to hydroperoxide
LEO79_13410	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LEO79_13415	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LEO79_13420	COG0762	integral membrane protein
LEO79_13425	COG1872	DUF167
LEO79_13445	COG3112	Uncharacterised protein family (UPF0231)
LEO79_13450	COG3835	regulator
LEO79_13455	COG2610	gluconate transmembrane transporter activity
LEO79_13460	COG1929	Belongs to the glycerate kinase type-1 family
LEO79_13475	COG0583	DNA-binding transcription factor activity
LEO79_13480	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LEO79_13495	COG0347	Belongs to the P(II) protein family
LEO79_13510	COG3842	ATPase activity
LEO79_13515	COG2837	iron assimilation
LEO79_13520	COG1438	arginine binding
LEO79_13525	COG1126	abc transporter atp-binding protein
LEO79_13530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LEO79_13535	COG4215	(ABC) transporter
LEO79_13540	COG4160	amino acid transport
LEO79_13545	COG0039	L-malate dehydrogenase activity
LEO79_13550	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
LEO79_13555	COG1017	nitric oxide dioxygenase activity
LEO79_13555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LEO79_13565	COG4536	flavin adenine dinucleotide binding
LEO79_13570	COG4137	Cytochrome C assembly protein
LEO79_13575	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LEO79_13580	COG0228	four-way junction DNA binding
LEO79_13585	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LEO79_13590	COG0336	Belongs to the RNA methyltransferase TrmD family
LEO79_13595	COG0335	large ribosomal subunit rRNA binding
LEO79_13610	COG1051	belongs to the nudix hydrolase family
LEO79_13620	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LEO79_13625	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LEO79_13630	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LEO79_13640	COG0583	DNA-binding transcription factor activity
LEO79_13645	COG0640	Transcriptional regulator
LEO79_13650	COG0268	Binds directly to 16S ribosomal RNA
LEO79_13655	COG0728	peptidoglycan biosynthetic process
LEO79_13660	COG0196	riboflavin kinase activity
LEO79_13665	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LEO79_13670	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LEO79_13675	COG1047	Peptidyl-prolyl cis-trans
LEO79_13680	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LEO79_13720	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LEO79_13720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LEO79_13735	COG1854	S-ribosylhomocysteine lyase activity
LEO79_13740	COG3706	GGDEF domain
LEO79_13745	COG0557	exoribonuclease II activity
LEO79_13750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LEO79_13760	COG2153	protein acetylation
LEO79_13770	COG1914	H( )-stimulated, divalent metal cation uptake system
LEO79_13775	COG0360	Binds together with S18 to 16S ribosomal RNA
LEO79_13780	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LEO79_13785	COG0359	binds to the 23S rRNA
LEO79_13825	COG1238	metal cluster binding
LEO79_13830	COG0612	Peptidase, M16
LEO79_13835	COG2918	glutathione biosynthetic process
LEO79_13840	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LEO79_13845	COG1027	Aspartate ammonia-lyase
LEO79_13850	COG3030	protein affecting phage T7 exclusion by the F plasmid
LEO79_13855	COG0534	Mate efflux family protein
LEO79_13860	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LEO79_13865	COG0459	protein refolding
LEO79_13885	COG0564	pseudouridine synthase activity
LEO79_13890	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LEO79_13925	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LEO79_13935	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LEO79_13940	COG4208	sulfate ABC transporter
LEO79_13945	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LEO79_13950	COG0583	DNA-binding transcription factor activity
LEO79_13955	COG3397	chitin binding
LEO79_13960	COG0840	transmembrane signaling receptor activity
LEO79_13985	COG1328	CTP reductase activity
LEO79_13990	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LEO79_14005	COG1448	Aminotransferase
LEO79_14010	COG2194	sulfuric ester hydrolase activity
LEO79_14025	COG1215	transferase activity, transferring glycosyl groups
LEO79_14030	COG1215	transferase activity, transferring glycosyl groups
LEO79_14040	COG3118	belongs to the thioredoxin family
LEO79_14040	COG0457	Tetratricopeptide repeat
LEO79_14075	COG0513	Belongs to the DEAD box helicase family
LEO79_14080	COG0840	transmembrane signaling receptor activity
LEO79_14090	COG4166	transmembrane transport
LEO79_14105	COG1024	Enoyl-CoA hydratase
LEO79_14120	COG4221	oxidoreductase activity
LEO79_14125	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LEO79_14130	COG0442	prolyl-tRNA aminoacylation
LEO79_14135	COG0840	transmembrane signaling receptor activity
LEO79_14140	COG0632	four-way junction helicase activity
LEO79_14145	COG2255	four-way junction helicase activity
LEO79_14155	COG1271	oxidase subunit
LEO79_14160	COG1294	oxidase, subunit
LEO79_14165	COG4890	Cyd operon protein YbgT
LEO79_14170	COG3790	cyd operon protein YbgE
LEO79_14175	COG0824	Thioesterase
LEO79_14180	COG0811	peptide transport
LEO79_14195	COG0823	Involved in the tonB-independent uptake of proteins
LEO79_14200	COG2885	chlorophyll binding
LEO79_14205	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
LEO79_14280	COG0840	transmembrane signaling receptor activity
LEO79_14285	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LEO79_14295	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LEO79_14300	COG1640	4-alpha-glucanotransferase
LEO79_14305	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LEO79_14335	COG2130	NADP-dependent
LEO79_14340	COG1846	Transcriptional regulator
LEO79_14370	COG0561	phosphatase activity
LEO79_14385	COG0733	neurotransmitter:sodium symporter activity
LEO79_14390	COG0733	neurotransmitter:sodium symporter activity
LEO79_14405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LEO79_14420	COG1794	racemase activity, acting on amino acids and derivatives
LEO79_14435	COG1022	Amp-dependent synthetase and ligase
LEO79_14445	COG0456	acetyltransferase
LEO79_14460	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LEO79_14465	COG5002	protein histidine kinase activity
LEO79_14465	COG5001	Diguanylate cyclase
LEO79_14490	COG0456	acetyltransferase
LEO79_14495	COG1902	pentaerythritol trinitrate reductase activity
LEO79_14505	COG2852	Protein conserved in bacteria
LEO79_14515	COG2957	Belongs to the agmatine deiminase family
LEO79_14520	COG0154	amidase activity
LEO79_14550	COG1917	Cupin 2, conserved barrel domain protein
LEO79_14550	COG2207	Transcriptional regulator
LEO79_14560	COG0513	Belongs to the DEAD box helicase family
LEO79_14565	COG2199	diguanylate cyclase activity
LEO79_14565	COG2203	Gaf domain
LEO79_14600	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
LEO79_14610	COG0577	efflux transmembrane transporter activity
LEO79_14610	COG1136	(ABC) transporter
LEO79_14615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LEO79_14620	COG0745	RESPONSE REGULATOR receiver
LEO79_14625	COG2205	protein histidine kinase activity
LEO79_14690	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LEO79_14700	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
LEO79_14705	COG1178	ABC-type Fe3 transport system permease component
LEO79_14710	COG4143	(ABC) transporter
LEO79_14725	COG0066	3-isopropylmalate dehydratase activity
LEO79_14730	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LEO79_14735	COG0473	3-isopropylmalate dehydrogenase activity
LEO79_14740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LEO79_14765	COG0028	Belongs to the TPP enzyme family
LEO79_14770	COG0440	acetolactate synthase activity
LEO79_14775	COG0857	belongs to the CobB CobQ family
LEO79_14775	COG0280	phosphate acetyltransferase
LEO79_14780	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LEO79_14785	COG3092	negative regulation of chromosome organization
LEO79_14790	COG3013	Belongs to the UPF0304 family
LEO79_14795	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LEO79_14800	COG2716	regulation of RNA biosynthetic process
LEO79_14805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LEO79_14810	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
LEO79_14815	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LEO79_14830	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
LEO79_14850	COG0784	Response regulator, receiver
LEO79_14850	COG2198	Histidine kinase
LEO79_14850	COG5002	protein histidine kinase activity
LEO79_14855	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LEO79_14865	COG0784	Response regulator, receiver
LEO79_14865	COG2205	protein histidine kinase activity
LEO79_14885	COG1464	Belongs to the NlpA lipoprotein family
LEO79_14890	COG2011	ABC-type metal ion transport system permease component
LEO79_14895	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LEO79_14915	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LEO79_14915	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LEO79_14920	COG0802	atpase or kinase
LEO79_14930	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LEO79_14935	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LEO79_14940	COG1923	regulation of RNA biosynthetic process
LEO79_14945	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LEO79_14950	COG0330	HflC and HflK could
LEO79_14955	COG0330	HflC and HflK could
LEO79_14960	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
LEO79_14965	COG0142	geranyltranstransferase activity
LEO79_14970	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LEO79_14975	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LEO79_14980	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LEO79_14985	COG3314	Sporulation integral membrane protein YlbJ
LEO79_14990	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LEO79_14995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEO79_15005	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LEO79_15010	COG2967	ApaG domain
LEO79_15015	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LEO79_15020	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LEO79_15030	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LEO79_15035	COG3178	'Phosphotransferase
LEO79_15040	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LEO79_15045	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LEO79_15050	COG2252	PERMEase
LEO79_15060	COG0488	(ABC) transporter
LEO79_15065	COG0741	lytic transglycosylase activity
LEO79_15070	COG0463	Glycosyl transferase, family 2
LEO79_15080	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LEO79_15105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEO79_15115	COG3721	Heme iron utilization protein
LEO79_15120	COG0748	coenzyme F420 binding
LEO79_15145	COG2814	Major facilitator Superfamily
LEO79_15150	COG2202	Pas domain
LEO79_15150	COG2205	protein histidine kinase activity
LEO79_15160	COG2226	methyltransferase
LEO79_15170	COG1765	OsmC-like protein
LEO79_15185	COG3954	Phosphoribulokinase
LEO79_15190	COG3089	Belongs to the UPF0270 family
LEO79_15195	COG3706	GGDEF domain
LEO79_15195	COG4251	negative regulation of phosphorylation
LEO79_15195	COG5001	Diguanylate cyclase
LEO79_15195	COG2203	Gaf domain
LEO79_15200	COG0429	hydrolase of the alpha beta-hydrolase fold
LEO79_15205	COG0784	Response regulator, receiver
LEO79_15205	COG0835	chemotaxis
LEO79_15215	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LEO79_15220	COG1047	Peptidyl-prolyl cis-trans
LEO79_15225	COG2900	Belongs to the SlyX family
LEO79_15235	COG0545	Peptidyl-prolyl cis-trans isomerase
LEO79_15240	COG2204	response regulator
LEO79_15260	COG0737	Belongs to the 5'-nucleotidase family
LEO79_15275	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LEO79_15280	COG0506	proline dehydrogenase activity
LEO79_15280	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LEO79_15280	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LEO79_15290	COG0114	fumarate hydratase activity
LEO79_15300	COG1566	PFAM secretion protein HlyD family protein
LEO79_15370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LEO79_15380	COG1280	lysine exporter protein (LysE YggA)
LEO79_15385	COG0826	peptidase U32
LEO79_15395	COG3813	Protein conserved in bacteria
LEO79_15415	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LEO79_15440	COG0300	oxidoreductase activity
LEO79_15460	COG2610	gluconate transmembrane transporter activity
LEO79_15465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LEO79_15470	COG3622	Belongs to the hyi family
LEO79_15475	COG0235	Class ii aldolase
LEO79_15485	COG2084	Dehydrogenase
LEO79_15490	COG1349	DNA-binding transcription factor activity
LEO79_15500	COG2133	pyrroloquinoline quinone binding
LEO79_15510	COG0582	viral genome integration into host DNA
LEO79_15535	COG1160	GTP binding
LEO79_15570	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LEO79_15585	COG2801	Transposase and inactivated derivatives
LEO79_15615	COG1605	Chorismate mutase
LEO79_15615	COG0077	Prephenate dehydratase
LEO79_15640	COG3272	Protein of unknown function (DUF1722)
LEO79_15645	COG0789	Transcriptional regulator
LEO79_15650	COG0415	Belongs to the DNA photolyase family
LEO79_15660	COG4221	oxidoreductase activity
LEO79_15675	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LEO79_15700	COG0783	Belongs to the Dps family
LEO79_15705	COG1151	hydroxylamine reductase activity
LEO79_15715	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LEO79_15735	COG1447	Phosphotransferase system cellobiose-specific component IIA
LEO79_15740	COG2723	6-phospho-beta-galactosidase activity
LEO79_15750	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LEO79_15755	COG2273	Hydrolase Family 16
LEO79_15755	COG5297	Belongs to the glycosyl hydrolase family 6
LEO79_15760	COG1472	Belongs to the glycosyl hydrolase 3 family
LEO79_15765	COG0840	transmembrane signaling receptor activity
LEO79_15770	COG2182	Extracellular solute-binding protein
LEO79_15775	COG1609	Transcriptional regulator
LEO79_15795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LEO79_15800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LEO79_15810	COG5002	protein histidine kinase activity
LEO79_15815	COG0659	secondary active sulfate transmembrane transporter activity
LEO79_15825	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LEO79_15830	COG1666	GTP binding
LEO79_15845	COG2211	Major facilitator Superfamily
LEO79_15855	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LEO79_15865	COG2813	Specifically methylates the guanine in position
LEO79_15870	COG0271	Belongs to the BolA IbaG family
LEO79_15875	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LEO79_15880	COG1805	sodium ion transport
LEO79_15885	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LEO79_15890	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LEO79_15895	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LEO79_15900	COG2871	sodium ion transport
LEO79_15905	COG1477	protein flavinylation
LEO79_15920	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LEO79_15925	COG0840	transmembrane signaling receptor activity
LEO79_15930	COG0583	DNA-binding transcription factor activity
LEO79_15945	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
LEO79_15955	COG0473	3-isopropylmalate dehydrogenase activity
LEO79_15960	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LEO79_15965	COG1611	Belongs to the LOG family
LEO79_15980	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LEO79_15980	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LEO79_15990	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
LEO79_16015	COG3098	single-species biofilm formation
LEO79_16020	COG0564	pseudouridine synthase activity
LEO79_16035	COG4580	involved in the transport of maltose and maltodextrins
LEO79_16045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LEO79_16045	COG1263	PTS System
LEO79_16060	COG2171	N-acyltransferase activity
LEO79_16065	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LEO79_16070	COG0024	Methionine aminopeptidase
LEO79_16075	COG0052	Belongs to the universal ribosomal protein uS2 family
LEO79_16080	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LEO79_16085	COG0528	UMP kinase activity
LEO79_16090	COG0233	cytoplasmic translational termination
LEO79_16095	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LEO79_16100	COG0575	Belongs to the CDS family
LEO79_16105	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LEO79_16110	COG0750	zinc metalloprotease
LEO79_16125	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LEO79_16130	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LEO79_16135	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LEO79_16140	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LEO79_16145	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LEO79_16155	COG0825	malonyl-CoA metabolic process
LEO79_16170	COG0814	amino acid
LEO79_16175	COG0531	amino acid
LEO79_16185	COG0488	(ABC) transporter
LEO79_16200	COG0037	tRNA processing
LEO79_16205	COG3706	GGDEF domain
LEO79_16240	COG0366	Alpha amylase catalytic
LEO79_16255	COG0463	Glycosyl transferase, family 2
LEO79_16270	COG2989	Protein conserved in bacteria
LEO79_16275	COG3108	Peptidase M15
LEO79_16285	COG2860	membrane
LEO79_16295	COG1196	nuclear chromosome segregation
LEO79_16300	COG3115	cell septum assembly
LEO79_16305	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LEO79_16315	COG1328	CTP reductase activity
LEO79_16320	COG0602	queuosine metabolic process
LEO79_16345	COG1566	PFAM secretion protein HlyD family protein
LEO79_16355	COG3290	protein histidine kinase activity
LEO79_16370	COG0667	Aldo Keto reductase
LEO79_16380	COG0697	spore germination
LEO79_16395	COG3284	Transcriptional regulator
LEO79_16400	COG3706	GGDEF domain
LEO79_16405	COG0346	lactoylglutathione lyase activity
LEO79_16410	COG0745	RESPONSE REGULATOR receiver
LEO79_16415	COG5002	protein histidine kinase activity
LEO79_16425	COG4783	chaperone-mediated protein folding
LEO79_16435	COG1940	carbohydrate kinase activity
LEO79_16440	COG3142	Participates in the control of copper homeostasis
LEO79_16465	COG0545	Peptidyl-prolyl cis-trans isomerase
LEO79_16485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LEO79_16490	COG4597	amino acid ABC transporter
LEO79_16495	COG0765	amino acid transport
LEO79_16500	COG1126	abc transporter atp-binding protein
LEO79_16510	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LEO79_16515	COG0678	peroxiredoxin activity
LEO79_16525	COG0019	diaminopimelate decarboxylase activity
LEO79_16530	COG1115	amino acid carrier protein
LEO79_16535	COG0095	Lipoate-protein ligase
LEO79_16540	COG2233	PERMEase
LEO79_16560	COG2207	Transcriptional regulator
LEO79_16565	COG0281	malic enzyme
LEO79_16595	COG0733	neurotransmitter:sodium symporter activity
LEO79_16600	COG1752	Esterase of the alpha-beta hydrolase superfamily
LEO79_16605	COG3706	GGDEF domain
LEO79_16615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LEO79_16620	COG1032	radical SAM domain protein
LEO79_16655	COG0673	inositol 2-dehydrogenase activity
LEO79_16660	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LEO79_16665	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LEO79_16670	COG0739	heme binding
LEO79_16670	COG0741	lytic transglycosylase activity
LEO79_16670	COG1196	nuclear chromosome segregation
LEO79_16695	COG0788	formyltetrahydrofolate deformylase activity
LEO79_16700	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LEO79_16710	COG3118	belongs to the thioredoxin family
LEO79_16720	COG0791	NLP P60 protein
LEO79_16725	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
LEO79_16740	COG1376	ErfK ybiS ycfS ynhG family protein
LEO79_16740	COG1388	LysM domain
LEO79_16750	COG2205	protein histidine kinase activity
LEO79_16750	COG0784	Response regulator, receiver
LEO79_16775	COG2205	protein histidine kinase activity
LEO79_16775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LEO79_16780	COG3384	dioxygenase
LEO79_16790	COG1283	sodium-dependent phosphate transmembrane transporter activity
LEO79_16800	COG0531	amino acid
LEO79_16805	COG0531	amino acid
LEO79_16820	COG1012	belongs to the aldehyde dehydrogenase family
LEO79_16825	COG1396	sequence-specific DNA binding
LEO79_16825	COG1917	Cupin 2, conserved barrel domain protein
LEO79_16830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LEO79_16865	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LEO79_16865	COG4651	solute:proton antiporter activity
LEO79_16880	COG2974	May be involved in recombination
LEO79_16885	COG1247	-acetyltransferase
LEO79_16890	COG0420	3'-5' exonuclease activity
LEO79_16900	COG3038	cytochrome b561
LEO79_16905	COG2190	(PTS) system
LEO79_16915	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LEO79_16920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LEO79_16925	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LEO79_16940	COG1720	tRNA m6t6A37 methyltransferase activity
LEO79_16960	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LEO79_16965	COG4988	ABC transporter
LEO79_16980	COG0745	RESPONSE REGULATOR receiver
LEO79_16990	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LEO79_17005	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
LEO79_17010	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
LEO79_17020	COG0083	homoserine kinase activity
LEO79_17025	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LEO79_17055	COG3220	belongs to the UPF0276 family
LEO79_17085	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LEO79_17090	COG1289	transmembrane transporter activity
LEO79_17095	COG1763	Mo-molybdopterin cofactor biosynthetic process
LEO79_17100	COG0746	molybdenum cofactor guanylyltransferase activity
LEO79_17105	COG0281	malic enzyme
LEO79_17135	COG3264	Mechanosensitive ion channel
LEO79_17135	COG1196	nuclear chromosome segregation
LEO79_17145	COG2850	peptidyl-arginine hydroxylation
LEO79_17150	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LEO79_17155	COG2915	High frequency lysogenization protein hflD homolog
LEO79_17160	COG0482	sulfurtransferase activity
LEO79_17170	COG1187	pseudouridine synthase activity
LEO79_17175	COG0456	acetyltransferase
LEO79_17180	COG0789	Transcriptional regulator
LEO79_17220	COG0538	isocitrate dehydrogenase activity
LEO79_17230	COG3048	D-serine ammonia-lyase activity
LEO79_17235	COG0583	DNA-binding transcription factor activity
LEO79_17240	COG2916	Histone family protein nucleoid-structuring protein H-NS
LEO79_17245	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LEO79_17250	COG2375	cellular response to nickel ion
LEO79_17255	COG1538	Outer membrane efflux protein
LEO79_17260	COG1136	(ABC) transporter
LEO79_17260	COG0577	efflux transmembrane transporter activity
LEO79_17265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LEO79_17275	COG0497	DNA recombination
LEO79_17280	COG3706	GGDEF domain
LEO79_17285	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LEO79_17290	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LEO79_17295	COG0443	Heat shock 70 kDa protein
LEO79_17300	COG0484	heat shock protein binding
LEO79_17330	COG1285	pathogenesis
LEO79_17340	COG0446	pyridine nucleotide-disulphide oxidoreductase
LEO79_17350	COG0640	Transcriptional regulator
LEO79_17380	COG0095	Lipoate-protein ligase
LEO79_17395	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LEO79_17400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LEO79_17410	COG0708	Exodeoxyribonuclease III
LEO79_17420	COG0745	RESPONSE REGULATOR receiver
LEO79_17435	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
LEO79_17450	COG1846	Transcriptional regulator
LEO79_17470	COG0583	DNA-binding transcription factor activity
LEO79_17475	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LEO79_17480	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LEO79_17485	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LEO79_17490	COG1845	cytochrome c oxidase, subunit III
LEO79_17495	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LEO79_17500	COG0109	protoheme IX farnesyltransferase activity
LEO79_17505	COG2814	Major facilitator Superfamily
LEO79_17510	COG5507	3-demethylubiquinone-9 3-methyltransferase
LEO79_17515	COG2175	clavaminate synthase activity
LEO79_17520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LEO79_17525	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LEO79_17530	COG4521	taurine ABC transporter
LEO79_17595	COG0159	tryptophan synthase activity
LEO79_17600	COG0133	tryptophan synthase activity
LEO79_17605	COG0134	indole-3-glycerol-phosphate synthase activity
LEO79_17605	COG0135	phosphoribosylanthranilate isomerase activity
LEO79_17610	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LEO79_17615	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LEO79_17615	COG0512	Glutamine amidotransferase of anthranilate synthase
LEO79_17620	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LEO79_17625	COG0613	PHP domain protein
LEO79_17630	COG0009	L-threonylcarbamoyladenylate synthase
LEO79_17640	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LEO79_17655	COG1946	Acyl-CoA thioesterase
LEO79_17670	COG1309	transcriptional regulator
LEO79_17675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LEO79_17680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LEO79_17750	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LEO79_17760	COG1960	acyl-CoA dehydrogenase activity
LEO79_17765	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LEO79_17775	COG0469	pyruvate kinase activity
LEO79_17780	COG1737	Transcriptional regulator
LEO79_17805	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LEO79_17845	COG1215	transferase activity, transferring glycosyl groups
LEO79_17850	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LEO79_17900	COG0297	glycogen (starch) synthase activity
LEO79_17900	COG0438	transferase activity, transferring glycosyl groups
LEO79_17905	COG1216	Glycosyl transferase, family 2
LEO79_17925	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LEO79_17930	COG0489	protein tyrosine kinase activity
LEO79_17930	COG3206	protein involved in exopolysaccharide biosynthesis
LEO79_17950	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LEO79_17960	COG3132	Protein of unknown function, DUF480
LEO79_18000	COG1278	Cold shock
LEO79_18025	COG4166	transmembrane transport
LEO79_18030	COG0697	spore germination
LEO79_18040	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LEO79_18055	COG4166	transmembrane transport
LEO79_18060	COG0622	Phosphoesterase
LEO79_18075	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
LEO79_18080	COG0784	Response regulator, receiver
LEO79_18080	COG0835	chemotaxis
LEO79_18085	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LEO79_18090	COG1815	bacterial-type flagellum-dependent cell motility
LEO79_18105	COG1749	Flagellar hook protein flgE
LEO79_18120	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
LEO79_18125	COG1706	bacterial-type flagellum-dependent cell motility
LEO79_18130	COG1705	Flagellar rod assembly protein muramidase FlgJ
LEO79_18130	COG3951	Flagellar rod assembly protein muramidase FlgJ
LEO79_18145	COG2239	Acts as a magnesium transporter
LEO79_18155	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LEO79_18160	COG2716	regulation of RNA biosynthetic process
LEO79_18185	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LEO79_18190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LEO79_18195	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LEO79_18200	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LEO79_18220	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LEO79_18235	COG0590	tRNA wobble adenosine to inosine editing
LEO79_18240	COG0573	inorganic phosphate transmembrane transporter activity
LEO79_18245	COG0581	inorganic phosphate transmembrane transporter activity
LEO79_18250	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LEO79_18255	COG0704	Plays a role in the regulation of phosphate uptake
LEO79_18260	COG1253	flavin adenine dinucleotide binding
LEO79_18275	COG0531	amino acid
LEO79_18290	COG1126	abc transporter atp-binding protein
LEO79_18295	COG0765	amino acid transport
LEO79_18300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LEO79_18305	COG3706	GGDEF domain
LEO79_18310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LEO79_18330	COG1785	Belongs to the alkaline phosphatase family
LEO79_18335	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LEO79_18340	COG0477	Major facilitator Superfamily
LEO79_18345	COG0123	including yeast histone deacetylase and acetoin utilization protein
LEO79_18355	COG1199	ATP-dependent helicase activity
LEO79_18370	COG1448	Aminotransferase
LEO79_18375	COG0433	COG0433 Predicted ATPase
LEO79_18390	COG0658	competence protein
LEO79_18390	COG2333	competence protein COMEC
LEO79_18395	COG1132	(ABC) transporter
LEO79_18400	COG1663	tetraacyldisaccharide 4'-kinase activity
LEO79_18405	COG2835	tetraacyldisaccharide 4'-kinase activity
LEO79_18410	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LEO79_18415	COG2197	response regulator
LEO79_18420	COG0322	excinuclease ABC activity
LEO79_18445	COG0604	alcohol dehydrogenase
LEO79_18450	COG1309	transcriptional regulator
LEO79_18455	COG2261	transglycosylase associated protein
LEO79_18460	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LEO79_18470	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LEO79_18480	COG2801	Transposase and inactivated derivatives
LEO79_18480	COG3415	Transposase
LEO79_18495	COG2199	diguanylate cyclase activity
LEO79_18495	COG2203	Gaf domain
LEO79_18530	COG2119	membrane
LEO79_18535	COG0023	Translation Initiation Factor
LEO79_18545	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LEO79_18570	COG4139	cobalamin transport
LEO79_18575	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
LEO79_18580	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LEO79_18585	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LEO79_18590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LEO79_18595	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LEO79_18600	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LEO79_18610	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LEO79_18615	COG0505	Belongs to the CarA family
LEO79_18620	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LEO79_18625	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LEO79_18630	COG3706	GGDEF domain
LEO79_18660	COG0513	Belongs to the DEAD box helicase family
LEO79_18670	COG4104	PAAR repeat-containing protein
LEO79_18690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LEO79_18695	COG0765	amino acid transport
LEO79_18700	COG1126	abc transporter atp-binding protein
LEO79_18705	COG0493	'glutamate synthase
LEO79_18710	COG0069	glutamate synthase activity
LEO79_18710	COG0067	glutamate synthase
LEO79_18710	COG0070	glutamate synthase
LEO79_18715	COG1242	4 iron, 4 sulfur cluster binding
LEO79_18760	COG1113	amino acid transport
LEO79_18770	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LEO79_18775	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LEO79_18775	COG0574	Belongs to the PEP-utilizing enzyme family
LEO79_18790	COG1119	ATPase activity
LEO79_18810	COG1464	Belongs to the NlpA lipoprotein family
LEO79_18815	COG0671	phosphoesterase, PA-phosphatase related
LEO79_18820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LEO79_18825	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LEO79_18835	COG0101	tRNA pseudouridine synthase activity
LEO79_18840	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LEO79_18845	COG0285	dihydrofolate synthase activity
LEO79_18850	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
LEO79_18855	COG2920	part of a sulfur-relay system
LEO79_18860	COG1289	transmembrane transporter activity
LEO79_18865	COG0670	Belongs to the BI1 family
LEO79_18905	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LEO79_18915	COG5001	Diguanylate cyclase
LEO79_18920	COG0564	pseudouridine synthase activity
LEO79_18935	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
LEO79_18945	COG0625	glutathione transferase activity
LEO79_18960	COG0367	asparagine synthase
LEO79_18970	COG0647	UMP catabolic process
LEO79_18975	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LEO79_18985	COG1902	pentaerythritol trinitrate reductase activity
LEO79_18990	COG1253	flavin adenine dinucleotide binding
LEO79_19000	COG0247	lactate metabolic process
LEO79_19000	COG0277	FAD linked oxidase domain protein
LEO79_19010	COG2050	protein possibly involved in aromatic compounds catabolism
LEO79_19025	COG5001	Diguanylate cyclase
LEO79_19030	COG0583	DNA-binding transcription factor activity
LEO79_19035	COG2814	Major facilitator Superfamily
LEO79_19040	COG2056	Na+-H+ antiporter family
LEO79_19045	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LEO79_19060	COG0483	inositol monophosphate 1-phosphatase activity
LEO79_19070	COG0625	glutathione transferase activity
LEO79_19075	COG0625	glutathione transferase activity
LEO79_19085	COG0601	transmembrane transport
LEO79_19090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEO79_19095	COG0444	Belongs to the ABC transporter superfamily
LEO79_19100	COG2814	Major facilitator Superfamily
LEO79_19120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LEO79_19125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LEO79_19130	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LEO79_19135	COG0509	glycine decarboxylation via glycine cleavage system
LEO79_19140	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LEO79_19140	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LEO79_19170	COG0477	Major facilitator Superfamily
LEO79_19175	COG3634	alkyl hydroperoxide reductase activity
LEO79_19180	COG0450	alkyl hydroperoxide reductase
LEO79_19185	COG0517	IMP dehydrogenase activity
LEO79_19190	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LEO79_19195	COG0343	queuine tRNA-ribosyltransferase activity
LEO79_19200	COG1862	Preprotein translocase
LEO79_19205	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LEO79_19210	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LEO79_19215	COG2897	thiosulfate sulfurtransferase activity
LEO79_19225	COG0826	peptidase U32
LEO79_19230	COG0826	peptidase U32
LEO79_19235	COG3154	lipid carrier protein
LEO79_19250	COG1104	cysteine desulfurase activity
LEO79_19255	COG0822	iron-sulfur transferase activity
LEO79_19265	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LEO79_19270	COG0443	Heat shock 70 kDa protein
LEO79_19275	COG0633	Ferredoxin
LEO79_19285	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LEO79_19290	COG0105	UTP biosynthetic process
LEO79_19295	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LEO79_19305	COG1426	Protein conserved in bacteria
LEO79_19310	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LEO79_19315	COG0124	histidyl-tRNA synthetase
LEO79_19320	COG2976	Protein conserved in bacteria
LEO79_19325	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LEO79_19330	COG1160	GTP binding
LEO79_19335	COG1645	bacterial-type flagellum-dependent swarming motility
LEO79_19340	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LEO79_19345	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEO79_19345	COG0047	phosphoribosylformylglycinamidine synthase activity
LEO79_19355	COG1007	ATP synthesis coupled electron transport
LEO79_19360	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LEO79_19370	COG0713	ATP synthesis coupled electron transport
LEO79_19375	COG0839	Belongs to the complex I subunit 6 family
LEO79_19380	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LEO79_19385	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LEO79_19390	COG1034	ATP synthesis coupled electron transport
LEO79_19405	COG0649	NAD binding
LEO79_19405	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LEO79_19410	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LEO79_19415	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LEO79_19420	COG1360	Flagellar Motor Protein
LEO79_19425	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LEO79_19445	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LEO79_19455	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
LEO79_19465	COG0724	RNA recognition motif
LEO79_19470	COG4989	oxidoreductase activity
LEO79_19495	COG0745	RESPONSE REGULATOR receiver
LEO79_19500	COG0583	DNA-binding transcription factor activity
LEO79_19510	COG5001	Diguanylate cyclase
LEO79_19510	COG3300	MHYT domain
LEO79_19515	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
LEO79_19545	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LEO79_19550	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LEO79_19555	COG0539	negative regulation of cytoplasmic translation
LEO79_19560	COG0776	regulation of translation
LEO79_19570	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LEO79_19590	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LEO79_19595	COG0602	queuosine metabolic process
LEO79_19600	COG3530	Putative quorum-sensing-regulated virulence factor
LEO79_19605	COG2096	Adenosyltransferase
LEO79_19610	COG2916	Histone family protein nucleoid-structuring protein H-NS
LEO79_19615	COG1757	Na H antiporter
LEO79_19620	COG1435	thymidine kinase activity
LEO79_19640	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LEO79_19650	COG1349	DNA-binding transcription factor activity
LEO79_19655	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
LEO79_19675	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LEO79_19680	COG0626	cystathionine gamma-synthase activity
LEO79_19690	COG2910	NAD(P)H-binding
LEO79_19695	COG0583	DNA-binding transcription factor activity
LEO79_19700	COG4977	sequence-specific DNA binding
LEO79_19700	COG1917	Cupin 2, conserved barrel domain protein
LEO79_19705	COG2200	EAL domain
LEO79_19710	COG3706	GGDEF domain
LEO79_19720	COG4774	siderophore transport
LEO79_19730	COG0583	DNA-binding transcription factor activity
LEO79_19735	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LEO79_19745	COG0517	IMP dehydrogenase activity
LEO79_19745	COG0516	GMP reductase activity
LEO79_19750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LEO79_19755	COG3046	protein related to deoxyribodipyrimidine photolyase
LEO79_19770	COG4235	cytochrome complex assembly
LEO79_19770	COG3088	subunit of a heme lyase
LEO79_19775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LEO79_19780	COG1138	Cytochrome C-type biogenesis protein
LEO79_19785	COG3301	Polysulphide reductase, NrfD
LEO79_19790	COG0437	4 iron, 4 sulfur cluster binding
LEO79_19795	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
LEO79_19815	COG0247	lactate metabolic process
LEO79_19820	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
LEO79_19825	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LEO79_19830	COG3012	SEC-C Motif Domain Protein
LEO79_19835	COG0840	transmembrane signaling receptor activity
LEO79_19840	COG1846	Transcriptional regulator
LEO79_19840	COG1940	carbohydrate kinase activity
LEO79_19845	COG3290	protein histidine kinase activity
LEO79_19850	COG4565	transcriptional regulatory protein
LEO79_19865	COG3181	Tripartite tricarboxylate transporter family receptor
LEO79_19870	COG0741	lytic transglycosylase activity
LEO79_19870	COG1196	nuclear chromosome segregation
LEO79_19870	COG0739	heme binding
LEO79_19875	COG0569	domain protein
LEO79_19875	COG2985	domain, Protein
LEO79_19885	COG0556	nucleotide-excision repair
LEO79_19895	COG0586	Pfam SNARE associated Golgi protein
LEO79_19900	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LEO79_19905	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LEO79_19910	COG2186	Transcriptional regulator
LEO79_19915	COG2719	SpoVR family
LEO79_19920	COG2718	Belongs to the UPF0229 family
LEO79_19925	COG2766	serine protein kinase
LEO79_19930	COG0514	ATP-dependent DNA helicase (RecQ)
LEO79_19935	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LEO79_19940	COG0814	amino acid
LEO79_19970	COG0058	SHG alpha-glucan phosphorylase activity
LEO79_19980	COG0471	metal ion transport
LEO79_19985	COG3118	belongs to the thioredoxin family
LEO79_19995	COG1132	(ABC) transporter
LEO79_20000	COG1132	(ABC) transporter
LEO79_20015	COG2501	S4 domain
LEO79_20025	COG3243	poly(R)-hydroxyalkanoic acid synthase
LEO79_20045	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
LEO79_20050	COG2329	Antibiotic biosynthesis monooxygenase
LEO79_20075	COG1742	UPF0060 membrane protein
LEO79_20090	COG0513	Belongs to the DEAD box helicase family
LEO79_20095	COG0386	Belongs to the glutathione peroxidase family
LEO79_20105	COG1181	Belongs to the D-alanine--D-alanine ligase family
LEO79_20110	COG3148	PFAM DTW domain containing protein
LEO79_20130	COG0730	response to heat
LEO79_20135	COG0583	DNA-binding transcription factor activity
LEO79_20150	COG3593	DNA synthesis involved in DNA repair
LEO79_20190	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LEO79_20195	COG1011	Hydrolase
LEO79_20200	COG1473	amidohydrolase
LEO79_20205	COG0205	6-phosphofructokinase activity
LEO79_20215	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LEO79_20220	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LEO79_20230	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
LEO79_20235	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LEO79_20240	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LEO79_20265	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LEO79_20270	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LEO79_20275	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LEO79_20285	COG0588	phosphoglycerate mutase activity
LEO79_20300	COG1280	lysine exporter protein (LysE YggA)
LEO79_20310	COG2824	Alkylphosphonate utilization operon protein PhnA
LEO79_20345	COG2840	Smr protein MutS2
LEO79_20350	COG2890	protein-(glutamine-N5) methyltransferase activity
LEO79_20355	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LEO79_20365	COG0513	Belongs to the DEAD box helicase family
LEO79_20370	COG5654	RES domain protein
LEO79_20380	COG0814	amino acid
LEO79_20385	COG1609	Transcriptional regulator
LEO79_20390	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LEO79_20390	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LEO79_20395	COG1105	Belongs to the carbohydrate kinase PfkB family
LEO79_20400	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LEO79_20400	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LEO79_20400	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LEO79_20405	COG3313	Fe-S protein
LEO79_20410	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LEO79_20415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LEO79_20420	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEO79_20425	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEO79_20435	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LEO79_20465	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LEO79_20470	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LEO79_20475	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LEO79_20480	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit