locus-tag	class	description
JC965_00015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JC965_00020	COG0358	DNA primase activity
JC965_00025	COG1610	YqeY-like protein
JC965_00030	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JC965_00035	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JC965_00045	COG4942	peptidase
JC965_00045	COG1388	LysM domain
JC965_00050	COG1238	metal cluster binding
JC965_00055	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JC965_00060	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JC965_00065	COG0585	pseudouridine synthase activity
JC965_00075	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JC965_00080	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
JC965_00085	COG0148	phosphopyruvate hydratase activity
JC965_00090	COG0504	CTP synthase activity
JC965_00095	COG3956	TIGRFAM MazG family protein
JC965_00100	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JC965_00105	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JC965_00115	COG4807	Protein conserved in bacteria
JC965_00120	COG3023	N-Acetylmuramoyl-L-alanine amidase
JC965_00125	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
JC965_00130	COG1381	Involved in DNA repair and RecF pathway recombination
JC965_00140	COG0571	ribonuclease III activity
JC965_00145	COG0681	Belongs to the peptidase S26 family
JC965_00150	COG0481	GTPase activity
JC965_00170	COG1595	DNA-templated transcription, initiation
JC965_00175	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JC965_00185	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
JC965_00190	COG0354	folic acid binding
JC965_00195	COG0583	DNA-binding transcription factor activity
JC965_00225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JC965_00235	COG0126	phosphoglycerate kinase activity
JC965_00240	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JC965_00245	COG1940	carbohydrate kinase activity
JC965_00250	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JC965_00255	COG2816	NAD+ diphosphatase activity
JC965_00260	COG4991	sh3 domain protein
JC965_00265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JC965_00280	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JC965_00285	COG1028	Short-chain dehydrogenase reductase Sdr
JC965_00295	COG1505	serine-type exopeptidase activity
JC965_00300	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JC965_00305	COG0765	amino acid transport
JC965_00310	COG0765	amino acid transport
JC965_00315	COG1126	abc transporter atp-binding protein
JC965_00320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JC965_00325	COG3174	membrane
JC965_00330	COG0110	maltose O-acetyltransferase activity
JC965_00360	COG1942	4-Oxalocrotonate Tautomerase
JC965_00370	COG0583	DNA-binding transcription factor activity
JC965_00375	COG0165	Argininosuccinate lyase
JC965_00380	COG0137	argininosuccinate synthase activity
JC965_00390	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JC965_00395	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JC965_00405	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JC965_00410	COG3447	MASE1 domain protein
JC965_00410	COG5002	protein histidine kinase activity
JC965_00410	COG5001	Diguanylate cyclase
JC965_00415	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JC965_00450	COG0583	DNA-binding transcription factor activity
JC965_00455	COG1380	Effector of murein hydrolase LrgA
JC965_00460	COG1346	cytolysis
JC965_00465	COG0527	aspartate kinase activity
JC965_00465	COG0460	homoserine dehydrogenase
JC965_00470	COG0626	cystathionine gamma-synthase activity
JC965_00485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JC965_00490	COG0814	amino acid
JC965_00495	COG1218	3'(2'),5'-bisphosphate nucleotidase
JC965_00500	COG0494	nUDIX hydrolase
JC965_00505	COG1011	Hydrolase
JC965_00510	COG1902	pentaerythritol trinitrate reductase activity
JC965_00520	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JC965_00535	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
JC965_00545	COG3156	type II secretion system protein K
JC965_00550	COG4795	General secretion pathway protein
JC965_00555	COG2165	general secretion pathway protein
JC965_00565	COG2165	general secretion pathway protein
JC965_00570	COG1459	type II secretion system
JC965_00575	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JC965_00585	COG3031	protein transport across the cell outer membrane
JC965_00595	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JC965_00600	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JC965_00620	COG3133	Outer membrane lipoprotein
JC965_00625	COG3025	triphosphatase activity
JC965_00630	COG1392	Phosphate transport regulator
JC965_00635	COG0306	phosphate transporter
JC965_00640	COG0617	tRNA 3'-terminal CCA addition
JC965_00645	COG3267	Type II secretory pathway component ExeA
JC965_00645	COG3409	Peptidoglycan-binding domain 1 protein
JC965_00655	COG1194	a g-specific adenine glycosylase
JC965_00660	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
JC965_00675	COG3240	lipase activity
JC965_00685	COG3009	Protein conserved in bacteria
JC965_00690	COG3008	intermembrane lipid transfer
JC965_00690	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JC965_00695	COG2995	paraquat-inducible protein a
JC965_00705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JC965_00710	COG2203	Gaf domain
JC965_00710	COG3706	GGDEF domain
JC965_00710	COG5001	Diguanylate cyclase
JC965_00710	COG4251	negative regulation of phosphorylation
JC965_00715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JC965_00720	COG2813	Specifically methylates the guanine in position
JC965_00725	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JC965_00730	COG0297	glycogen (starch) synthase activity
JC965_00770	COG1757	Na H antiporter
JC965_00785	COG3842	ATPase activity
JC965_00790	COG1176	ABC-type spermidine putrescine transport system, permease component I
JC965_00795	COG1177	transmembrane transport
JC965_00800	COG1012	belongs to the aldehyde dehydrogenase family
JC965_00805	COG0109	protoheme IX farnesyltransferase activity
JC965_00835	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
JC965_00845	COG1565	acr, cog1565
JC965_00845	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JC965_00850	COG1444	tRNA N-acetyltransferase activity
JC965_00870	COG1803	Methylglyoxal synthase
JC965_00885	COG0252	asparaginase activity
JC965_00905	COG1263	PTS System
JC965_00905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JC965_00910	COG0366	Alpha amylase catalytic
JC965_00915	COG0110	maltose O-acetyltransferase activity
JC965_00920	COG1522	sequence-specific DNA binding
JC965_00925	COG5006	permease, DMT superfamily
JC965_00950	COG3068	Protein conserved in bacteria
JC965_00960	COG0739	heme binding
JC965_00980	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
JC965_00985	COG1121	(ABC) transporter
JC965_00990	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JC965_00995	COG0583	DNA-binding transcription factor activity
JC965_01005	COG1573	uracil-dna glycosylase
JC965_01010	COG2962	Rard protein
JC965_01015	COG2827	Endonuclease containing a URI domain
JC965_01030	COG1842	Phage shock protein A
JC965_01035	COG0204	Acyl-transferase
JC965_01055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JC965_01065	COG0484	heat shock protein binding
JC965_01120	COG2966	Psort location CytoplasmicMembrane, score
JC965_01125	COG3610	response to peptide
JC965_01135	COG4175	Glycine betaine
JC965_01140	COG4176	ABC-type proline glycine betaine transport system permease component
JC965_01145	COG2113	Glycine betaine
JC965_01150	COG0175	sulfate reduction
JC965_01155	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JC965_01160	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JC965_01165	COG0384	phenazine biosynthesis protein PhzF
JC965_01170	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JC965_01185	COG0786	glutamate:sodium symporter activity
JC965_01190	COG0252	asparaginase activity
JC965_01195	COG3139	Protein of unknown function (DUF1315)
JC965_01215	COG0616	signal peptide processing
JC965_01220	COG0446	pyridine nucleotide-disulphide oxidoreductase
JC965_01220	COG1902	pentaerythritol trinitrate reductase activity
JC965_01225	COG0778	Nitroreductase
JC965_01235	COG0110	maltose O-acetyltransferase activity
JC965_01240	COG2264	protein methyltransferase activity
JC965_01245	COG0604	alcohol dehydrogenase
JC965_01250	COG0583	DNA-binding transcription factor activity
JC965_01255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JC965_01255	COG1263	PTS System
JC965_01255	COG2190	(PTS) system
JC965_01260	COG4145	pantothenate transmembrane transporter activity
JC965_01265	COG3924	membrane
JC965_01270	COG0439	Biotin carboxylase
JC965_01275	COG0511	ligase activity, forming carbon-carbon bonds
JC965_01280	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JC965_01285	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JC965_01300	COG3381	protein complex oligomerization
JC965_01310	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JC965_01320	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JC965_01325	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JC965_01325	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JC965_01340	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JC965_01345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JC965_01350	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JC965_01355	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JC965_01360	COG4172	Belongs to the ABC transporter superfamily
JC965_01370	COG0601	transmembrane transport
JC965_01375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JC965_01380	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JC965_01385	COG0142	geranyltranstransferase activity
JC965_01390	COG1722	exodeoxyribonuclease VII activity
JC965_01395	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JC965_01400	COG1360	Flagellar Motor Protein
JC965_01415	COG1534	Rna-binding protein
JC965_01420	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
JC965_01430	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JC965_01435	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JC965_01440	COG0149	triose-phosphate isomerase activity
JC965_01445	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JC965_01460	COG0779	Required for maturation of 30S ribosomal subunits
JC965_01465	COG0195	Participates in both transcription termination and antitermination
JC965_01470	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JC965_01475	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JC965_01480	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JC965_01485	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JC965_01490	COG1185	polyribonucleotide nucleotidyltransferase activity
JC965_01495	COG2211	Major facilitator Superfamily
JC965_01500	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
JC965_01505	COG1422	Protein of unknown function (DUF1090)
JC965_01510	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JC965_01515	COG0826	peptidase U32
JC965_01530	COG0312	modulator of DNA gyrase
JC965_01535	COG0312	modulator of DNA gyrase
JC965_01545	COG4974	Belongs to the 'phage' integrase family
JC965_01550	COG1970	mechanosensitive ion channel activity
JC965_01560	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JC965_01565	COG0789	Transcriptional regulator
JC965_01580	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JC965_01590	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JC965_01595	COG0321	lipoyl(octanoyl) transferase activity
JC965_01600	COG2921	Belongs to the UPF0250 family
JC965_01605	COG1686	Belongs to the peptidase S11 family
JC965_01610	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JC965_01615	COG2951	lytic endotransglycosylase activity
JC965_01620	COG0772	Belongs to the SEDS family
JC965_01625	COG0768	penicillin binding
JC965_01630	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JC965_01635	COG0799	negative regulation of ribosome biogenesis
JC965_01640	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JC965_01655	COG0495	leucyl-tRNA aminoacylation
JC965_01660	COG2888	peptidyl-tyrosine sulfation
JC965_01665	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JC965_01670	COG4535	Mg2 and Co2 transporter CorC
JC965_01675	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JC965_01680	COG1702	phosphate starvation-inducible protein PhoH
JC965_01685	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JC965_01690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JC965_01695	COG1335	isochorismatase
JC965_01710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JC965_01725	COG3706	GGDEF domain
JC965_01735	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JC965_01750	COG1464	Belongs to the NlpA lipoprotein family
JC965_01755	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JC965_01760	COG2011	ABC-type metal ion transport system permease component
JC965_01765	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JC965_01775	COG0516	GMP reductase activity
JC965_01780	COG4067	protein conserved in archaea
JC965_01780	COG0189	ligase activity
JC965_01800	COG0300	oxidoreductase activity
JC965_01820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JC965_01825	COG3214	Protein conserved in bacteria
JC965_01840	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
JC965_01845	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
JC965_01850	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JC965_01855	COG1053	succinate dehydrogenase
JC965_01875	COG0203	ribosomal protein L17
JC965_01880	COG0202	RNA polymerase activity
JC965_01885	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JC965_01890	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JC965_01895	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JC965_01900	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JC965_01905	COG0201	protein transport
JC965_01910	COG0200	Binds to the 23S rRNA
JC965_01915	COG1841	ribosomal large subunit assembly
JC965_01920	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JC965_01925	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JC965_01930	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JC965_01935	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JC965_01940	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JC965_01945	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JC965_01950	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JC965_01955	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JC965_01960	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JC965_01965	COG0255	Belongs to the universal ribosomal protein uL29 family
JC965_01970	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JC965_01975	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JC965_01980	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JC965_01985	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JC965_01990	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JC965_01995	COG0089	rRNA binding
JC965_02000	COG0088	Forms part of the polypeptide exit tunnel
JC965_02005	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JC965_02010	COG0051	transcription antitermination factor activity, RNA binding
JC965_02020	COG2205	protein histidine kinase activity
JC965_02030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JC965_02035	COG2183	response to ionizing radiation
JC965_02050	COG0596	Alpha beta hydrolase
JC965_02055	COG1040	competence protein
JC965_02060	COG0316	Belongs to the HesB IscA family
JC965_02060	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JC965_02065	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JC965_02070	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
JC965_02075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JC965_02080	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JC965_02085	COG4942	peptidase
JC965_02095	COG1609	Transcriptional regulator
JC965_02110	COG0800	Aldolase
JC965_02115	COG0129	dihydroxy-acid dehydratase activity
JC965_02120	COG3265	gluconokinase activity
JC965_02125	COG2610	gluconate transmembrane transporter activity
JC965_02130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JC965_02135	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JC965_02145	COG0456	acetyltransferase
JC965_02155	COG1490	D-aminoacyl-tRNA deacylase activity
JC965_02160	COG1295	ribonuclease BN
JC965_02165	COG1217	gtp-binding protein TYPA
JC965_02170	COG0174	glutamine synthetase
JC965_02180	COG3852	Histidine kinase
JC965_02190	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JC965_02195	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JC965_02205	COG3078	GTPase activator activity
JC965_02215	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JC965_02220	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JC965_02225	COG0408	coproporphyrinogen oxidase activity
JC965_02230	COG0009	L-threonylcarbamoyladenylate synthase
JC965_02235	COG0551	DNA topoisomerase type I activity
JC965_02240	COG2922	Belongs to the Smg family
JC965_02245	COG0758	DNA mediated transformation
JC965_02255	COG0242	peptide deformylase activity
JC965_02260	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JC965_02265	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JC965_02265	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JC965_02270	COG0569	domain protein
JC965_02275	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JC965_02280	COG1322	Protein conserved in bacteria
JC965_02300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JC965_02310	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JC965_02310	COG0519	Catalyzes the synthesis of GMP from XMP
JC965_02320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JC965_02325	COG1396	sequence-specific DNA binding
JC965_02330	COG1012	belongs to the aldehyde dehydrogenase family
JC965_02340	COG2962	Rard protein
JC965_02350	COG1280	lysine exporter protein (LysE YggA)
JC965_02395	COG0583	DNA-binding transcription factor activity
JC965_02415	COG0210	DNA helicase
JC965_02420	COG1744	ABC transporter substrate-binding protein PnrA-like
JC965_02425	COG3845	ABC transporter
JC965_02430	COG4603	Belongs to the binding-protein-dependent transport system permease family
JC965_02435	COG1079	Belongs to the binding-protein-dependent transport system permease family
JC965_02440	COG0583	DNA-binding transcription factor activity
JC965_02465	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JC965_02470	COG0385	Bile acid
JC965_02475	COG0531	amino acid
JC965_02480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JC965_02485	COG0531	amino acid
JC965_02490	COG2731	YhcH YjgK YiaL family protein
JC965_02495	COG3250	beta-galactosidase activity
JC965_02500	COG1609	Transcriptional regulator
JC965_02530	COG2202	Pas domain
JC965_02530	COG2205	protein histidine kinase activity
JC965_02535	COG2814	Major facilitator Superfamily
JC965_02560	COG0748	coenzyme F420 binding
JC965_02565	COG3721	Heme iron utilization protein
JC965_02575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JC965_02600	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JC965_02610	COG0463	Glycosyl transferase, family 2
JC965_02615	COG0741	lytic transglycosylase activity
JC965_02620	COG0488	(ABC) transporter
JC965_02630	COG2252	PERMEase
JC965_02635	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JC965_02640	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JC965_02645	COG3178	'Phosphotransferase
JC965_02650	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
JC965_02660	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JC965_02665	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JC965_02670	COG2967	ApaG domain
JC965_02675	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JC965_02685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JC965_02690	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JC965_02695	COG3314	Sporulation integral membrane protein YlbJ
JC965_02700	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JC965_02705	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JC965_02710	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JC965_02715	COG0142	geranyltranstransferase activity
JC965_02720	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
JC965_02725	COG0330	HflC and HflK could
JC965_02730	COG0330	HflC and HflK could
JC965_02735	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JC965_02740	COG1923	regulation of RNA biosynthetic process
JC965_02745	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JC965_02750	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JC965_02760	COG0802	atpase or kinase
JC965_02765	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JC965_02765	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JC965_02785	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JC965_02790	COG2011	ABC-type metal ion transport system permease component
JC965_02795	COG1464	Belongs to the NlpA lipoprotein family
JC965_02815	COG0784	Response regulator, receiver
JC965_02815	COG2205	protein histidine kinase activity
JC965_02825	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JC965_02830	COG2198	Histidine kinase
JC965_02830	COG5002	protein histidine kinase activity
JC965_02830	COG0784	Response regulator, receiver
JC965_02850	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
JC965_02865	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JC965_02870	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
JC965_02875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JC965_02880	COG2716	regulation of RNA biosynthetic process
JC965_02885	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JC965_02890	COG3013	Belongs to the UPF0304 family
JC965_02900	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JC965_02905	COG0857	belongs to the CobB CobQ family
JC965_02905	COG0280	phosphate acetyltransferase
JC965_02910	COG0440	acetolactate synthase activity
JC965_02915	COG0028	Belongs to the TPP enzyme family
JC965_02930	COG0671	phosphoesterase, PA-phosphatase related
JC965_02940	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JC965_02945	COG0473	3-isopropylmalate dehydrogenase activity
JC965_02950	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JC965_02955	COG0066	3-isopropylmalate dehydratase activity
JC965_02970	COG4143	(ABC) transporter
JC965_02975	COG1178	ABC-type Fe3 transport system permease component
JC965_02980	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
JC965_02990	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JC965_03000	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JC965_03040	COG2249	NAD(P)H dehydrogenase (quinone) activity
JC965_03045	COG0583	DNA-binding transcription factor activity
JC965_03050	COG4221	oxidoreductase activity
JC965_03065	COG1770	oligopeptidase
JC965_03070	COG2358	TRAP transporter, solute receptor (TAXI family
JC965_03085	COG3714	YhhN family
JC965_03100	COG0583	DNA-binding transcription factor activity
JC965_03110	COG1301	dicarboxylic acid transport
JC965_03120	COG2095	MarC family integral membrane protein
JC965_03130	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JC965_03140	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
JC965_03150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JC965_03175	COG0742	ribosomal rna small subunit methyltransferase
JC965_03180	COG0552	protein localization to endoplasmic reticulum
JC965_03185	COG2884	Cell division ATP-binding protein ftsE
JC965_03190	COG2177	Part of the ABC transporter FtsEX involved in
JC965_03200	COG0288	reversible hydration of carbon dioxide
JC965_03205	COG2188	Transcriptional regulator
JC965_03210	COG1228	amidohydrolase
JC965_03215	COG0010	Belongs to the arginase family
JC965_03220	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JC965_03225	COG2986	histidine ammonia-lyase
JC965_03230	COG0387	Pfam Sodium calcium exchanger
JC965_03235	COG2200	EAL domain
JC965_03290	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JC965_03295	COG1459	type II secretion system
JC965_03305	COG2165	general secretion pathway protein
JC965_03310	COG2165	general secretion pathway protein
JC965_03340	COG1077	Cell shape determining protein MreB Mrl
JC965_03345	COG1792	Involved in formation and maintenance of cell shape
JC965_03350	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JC965_03355	COG0424	maF-like protein
JC965_03360	COG1530	ribonuclease E activity
JC965_03365	COG3164	Protein of unknown function
JC965_03370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JC965_03375	COG0312	modulator of DNA gyrase
JC965_03390	COG0477	Major facilitator Superfamily
JC965_03400	COG2321	neutral zinc metallopeptidase
JC965_03435	COG0189	ligase activity
JC965_03440	COG0642	Histidine kinase
JC965_03445	COG0745	RESPONSE REGULATOR receiver
JC965_03460	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JC965_03465	COG0352	thiamine-phosphate diphosphorylase activity
JC965_03470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JC965_03480	COG2022	thiamine diphosphate biosynthetic process
JC965_03485	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JC965_03500	COG1032	radical SAM domain protein
JC965_03505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JC965_03515	COG3706	GGDEF domain
JC965_03520	COG1752	Esterase of the alpha-beta hydrolase superfamily
JC965_03555	COG0281	malic enzyme
JC965_03560	COG2207	Transcriptional regulator
JC965_03580	COG2233	PERMEase
JC965_03585	COG0095	Lipoate-protein ligase
JC965_03590	COG1115	amino acid carrier protein
JC965_03595	COG0019	diaminopimelate decarboxylase activity
JC965_03605	COG0678	peroxiredoxin activity
JC965_03610	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
JC965_03620	COG1126	abc transporter atp-binding protein
JC965_03625	COG0765	amino acid transport
JC965_03630	COG4597	amino acid ABC transporter
JC965_03635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JC965_03655	COG0545	Peptidyl-prolyl cis-trans isomerase
JC965_03675	COG3142	Participates in the control of copper homeostasis
JC965_03680	COG1940	carbohydrate kinase activity
JC965_03690	COG4783	chaperone-mediated protein folding
JC965_03700	COG5002	protein histidine kinase activity
JC965_03705	COG0745	RESPONSE REGULATOR receiver
JC965_03715	COG3706	GGDEF domain
JC965_03720	COG3284	Transcriptional regulator
JC965_03735	COG0697	spore germination
JC965_03745	COG0667	Aldo Keto reductase
JC965_03760	COG3290	protein histidine kinase activity
JC965_03770	COG1566	PFAM secretion protein HlyD family protein
JC965_03795	COG0602	queuosine metabolic process
JC965_03800	COG1328	CTP reductase activity
JC965_03810	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JC965_03815	COG3115	cell septum assembly
JC965_03820	COG1196	nuclear chromosome segregation
JC965_03830	COG2860	membrane
JC965_03840	COG3108	Peptidase M15
JC965_03845	COG2989	Protein conserved in bacteria
JC965_03860	COG0463	Glycosyl transferase, family 2
JC965_03875	COG0366	Alpha amylase catalytic
JC965_03910	COG3706	GGDEF domain
JC965_03915	COG0037	tRNA processing
JC965_03930	COG0488	(ABC) transporter
JC965_03955	COG3964	amidohydrolase
JC965_03985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JC965_03990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JC965_04000	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
JC965_04005	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JC965_04010	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JC965_04015	COG0723	plastoquinol--plastocyanin reductase activity
JC965_04020	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JC965_04025	COG2857	Cytochrome c1
JC965_04030	COG0625	glutathione transferase activity
JC965_04035	COG2969	positive regulation of protein catabolic process
JC965_04040	COG2823	Periplasmic or secreted lipoprotein
JC965_04045	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JC965_04050	COG0792	nuclease activity
JC965_04055	COG3107	peptidoglycan biosynthetic process
JC965_04060	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JC965_04070	COG2001	Belongs to the MraZ family
JC965_04075	COG0275	rRNA processing
JC965_04080	COG3116	cell division
JC965_04085	COG0768	penicillin binding
JC965_04090	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JC965_04095	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JC965_04100	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JC965_04105	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JC965_04110	COG0772	Belongs to the SEDS family
JC965_04115	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JC965_04120	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JC965_04125	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JC965_04130	COG0849	cell division
JC965_04135	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JC965_04140	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
JC965_04150	COG0653	protein targeting
JC965_04160	COG0494	nUDIX hydrolase
JC965_04165	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
JC965_04170	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
JC965_04180	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JC965_04185	COG1459	type II secretion system
JC965_04190	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JC965_04215	COG2186	Transcriptional regulator
JC965_04220	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JC965_04225	COG0508	dehydrogenase complex catalyzes the overall conversion of
JC965_04230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JC965_04240	COG0840	transmembrane signaling receptor activity
JC965_04245	COG0840	transmembrane signaling receptor activity
JC965_04250	COG1752	Esterase of the alpha-beta hydrolase superfamily
JC965_04255	COG1049	propionate catabolic process, 2-methylcitrate cycle
JC965_04260	COG2200	EAL domain
JC965_04270	COG1280	lysine exporter protein (LysE YggA)
JC965_04280	COG0523	cobalamin synthesis protein
JC965_04285	COG0477	Major facilitator Superfamily
JC965_04300	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JC965_04305	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JC965_04350	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JC965_04360	COG1546	Belongs to the CinA family
JC965_04365	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JC965_04375	COG3335	DDE superfamily endonuclease
JC965_04385	COG2003	Belongs to the UPF0758 family
JC965_04405	COG5489	Protein of unknown function (DUF736)
JC965_04445	COG1192	Involved in chromosome partitioning
JC965_04460	COG4959	Type IV secretory pathway protease TraF
JC965_04475	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JC965_04485	COG2814	Major facilitator Superfamily
JC965_04510	COG0640	Transcriptional regulator
JC965_04515	COG1230	cation diffusion facilitator family transporter
JC965_04520	COG1937	Protein conserved in bacteria
JC965_04525	COG2814	Major facilitator Superfamily
JC965_04530	COG0640	Transcriptional regulator
JC965_04540	COG0789	Transcriptional regulator
JC965_04545	COG0633	Ferredoxin
JC965_04570	COG0583	DNA-binding transcription factor activity
JC965_04595	COG4962	Type ii secretion system protein e
JC965_04600	COG3838	Conjugal transfer protein Trbc
JC965_04610	COG3451	type IV secretory pathway VirB4
JC965_04625	COG3846	protein secretion by the type IV secretion system
JC965_04650	COG1368	sulfuric ester hydrolase activity
JC965_04665	COG1285	pathogenesis
JC965_04685	COG4221	oxidoreductase activity
JC965_04700	COG1979	alcohol dehydrogenase
JC965_04710	COG2873	o-acetylhomoserine
JC965_04740	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JC965_04750	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JC965_04755	COG2949	membrane
JC965_04760	COG3291	Pkd domain containing protein
JC965_04765	COG0318	PFAM AMP-dependent synthetase and ligase
JC965_04775	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JC965_04780	COG0596	Alpha beta hydrolase
JC965_04785	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JC965_04790	COG1169	isochorismate synthase
JC965_04795	COG1575	Belongs to the MenA family. Type 1 subfamily
JC965_04815	COG0513	Belongs to the DEAD box helicase family
JC965_04820	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JC965_04825	COG0675	Transposase, IS605 OrfB family
JC965_04840	COG0037	tRNA processing
JC965_04845	COG0589	response to stress
JC965_04850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JC965_04865	COG2217	Heavy metal translocating P-type atpase
JC965_04875	COG2010	Cytochrome c
JC965_04890	COG3278	Belongs to the heme-copper respiratory oxidase family
JC965_04905	COG1956	GAF domain-containing protein
JC965_04910	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
JC965_04920	COG0308	aminopeptidase N
JC965_04930	COG2902	Dehydrogenase
JC965_04935	COG0167	dihydroorotate dehydrogenase activity
JC965_04945	COG0116	Belongs to the methyltransferase superfamily
JC965_04945	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JC965_04955	COG0488	(ABC) transporter
JC965_04970	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JC965_04975	COG1067	ATP-dependent peptidase activity
JC965_04985	COG3141	response to X-ray
JC965_05005	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JC965_05005	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JC965_05010	COG0509	glycine decarboxylation via glycine cleavage system
JC965_05015	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JC965_05020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JC965_05025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JC965_05045	COG2814	Major facilitator Superfamily
JC965_05055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JC965_05060	COG0601	transmembrane transport
JC965_05070	COG0625	glutathione transferase activity
JC965_05085	COG0483	inositol monophosphate 1-phosphatase activity
JC965_05100	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JC965_05105	COG2056	Na+-H+ antiporter family
JC965_05110	COG2814	Major facilitator Superfamily
JC965_05115	COG0583	DNA-binding transcription factor activity
JC965_05120	COG5001	Diguanylate cyclase
JC965_05135	COG2050	protein possibly involved in aromatic compounds catabolism
JC965_05145	COG0277	FAD linked oxidase domain protein
JC965_05145	COG0247	lactate metabolic process
JC965_05190	COG0776	regulation of translation
JC965_05195	COG0072	phenylalanine-tRNA ligase activity
JC965_05195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JC965_05200	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JC965_05205	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JC965_05210	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JC965_05215	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JC965_05220	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JC965_05250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JC965_05260	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JC965_05265	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JC965_05270	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JC965_05275	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
JC965_05280	COG3313	Fe-S protein
JC965_05285	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
JC965_05285	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JC965_05285	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JC965_05290	COG1105	Belongs to the carbohydrate kinase PfkB family
JC965_05295	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JC965_05295	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JC965_05300	COG1609	Transcriptional regulator
JC965_05305	COG0814	amino acid
JC965_05315	COG5654	RES domain protein
JC965_05320	COG0513	Belongs to the DEAD box helicase family
JC965_05335	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JC965_05340	COG2890	protein-(glutamine-N5) methyltransferase activity
JC965_05345	COG2840	Smr protein MutS2
JC965_05380	COG2824	Alkylphosphonate utilization operon protein PhnA
JC965_05425	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
JC965_05430	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
JC965_05440	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JC965_05445	COG1434	Gram-negative-bacterium-type cell wall biogenesis
JC965_05455	COG0205	6-phosphofructokinase activity
JC965_05460	COG1473	amidohydrolase
JC965_05465	COG1011	Hydrolase
JC965_05470	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JC965_05495	COG3593	DNA synthesis involved in DNA repair
JC965_05510	COG0583	DNA-binding transcription factor activity
JC965_05525	COG0840	transmembrane signaling receptor activity
JC965_05530	COG0632	four-way junction helicase activity
JC965_05535	COG2255	four-way junction helicase activity
JC965_05540	COG1271	oxidase subunit
JC965_05545	COG1294	oxidase, subunit
JC965_05550	COG4890	Cyd operon protein YbgT
JC965_05555	COG3790	cyd operon protein YbgE
JC965_05560	COG0824	Thioesterase
JC965_05565	COG0811	peptide transport
JC965_05580	COG0823	Involved in the tonB-independent uptake of proteins
JC965_05585	COG2885	chlorophyll binding
JC965_05590	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
JC965_05675	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JC965_05685	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JC965_05690	COG1640	4-alpha-glucanotransferase
JC965_05695	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JC965_05725	COG2130	NADP-dependent
JC965_05730	COG1846	Transcriptional regulator
JC965_05760	COG0561	phosphatase activity
JC965_05775	COG0733	neurotransmitter:sodium symporter activity
JC965_05780	COG0733	neurotransmitter:sodium symporter activity
JC965_05795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JC965_05810	COG1794	racemase activity, acting on amino acids and derivatives
JC965_05820	COG1022	Amp-dependent synthetase and ligase
JC965_05830	COG0456	acetyltransferase
JC965_05845	COG2425	protein containing a von Willebrand factor type A (vWA) domain
JC965_05850	COG5001	Diguanylate cyclase
JC965_05850	COG5002	protein histidine kinase activity
JC965_05860	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JC965_05870	COG0456	acetyltransferase
JC965_05880	COG0456	acetyltransferase
JC965_05885	COG1902	pentaerythritol trinitrate reductase activity
JC965_05895	COG2852	Protein conserved in bacteria
JC965_05905	COG2957	Belongs to the agmatine deiminase family
JC965_05910	COG0154	amidase activity
JC965_05980	COG0151	Belongs to the GarS family
JC965_05985	COG0138	bifunctional purine biosynthesis protein purh
JC965_06005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JC965_06010	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JC965_06020	COG0673	inositol 2-dehydrogenase activity
JC965_06030	COG1585	Membrane protein implicated in regulation of membrane protease activity
JC965_06035	COG0330	HflC and HflK could
JC965_06040	COG1648	precorrin-2 dehydrogenase activity
JC965_06040	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JC965_06045	COG0175	sulfate reduction
JC965_06050	COG2895	sulfate adenylyltransferase (ATP) activity
JC965_06055	COG3273	potassium ion transport
JC965_06055	COG0471	metal ion transport
JC965_06060	COG0529	Catalyzes the synthesis of activated sulfate
JC965_06105	COG1136	(ABC) transporter
JC965_06120	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
JC965_06135	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JC965_06140	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JC965_06145	COG0163	prenyltransferase activity
JC965_06160	COG1131	(ABC) transporter
JC965_06165	COG0842	Transport permease protein
JC965_06175	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JC965_06180	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JC965_06185	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JC965_06195	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JC965_06200	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JC965_06205	COG1489	DNA binding
JC965_06215	COG1643	Atp-dependent helicase
JC965_06220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JC965_06225	COG0346	lactoylglutathione lyase activity
JC965_06235	COG2076	Multidrug Resistance protein
JC965_06240	COG0583	DNA-binding transcription factor activity
JC965_06250	COG0671	phosphoesterase, PA-phosphatase related
JC965_06265	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JC965_06270	COG0038	chloride channel
JC965_06280	COG0316	Belongs to the HesB IscA family
JC965_06340	COG2826	transposase and inactivated derivatives, IS30 family
JC965_06350	COG5489	Protein of unknown function (DUF736)
JC965_06375	COG2003	Belongs to the UPF0758 family
JC965_06410	COG2003	Belongs to the UPF0758 family
JC965_06595	COG0270	DNA (cytosine-5-)-methyltransferase activity
JC965_06600	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JC965_06605	COG0629	single-stranded DNA binding
JC965_06670	COG2814	Major facilitator Superfamily
JC965_06675	COG3634	alkyl hydroperoxide reductase activity
JC965_06680	COG0450	alkyl hydroperoxide reductase
JC965_06685	COG0517	IMP dehydrogenase activity
JC965_06690	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JC965_06695	COG0343	queuine tRNA-ribosyltransferase activity
JC965_06700	COG1862	Preprotein translocase
JC965_06705	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JC965_06710	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JC965_06715	COG2897	thiosulfate sulfurtransferase activity
JC965_06725	COG0826	peptidase U32
JC965_06730	COG0826	peptidase U32
JC965_06735	COG3154	lipid carrier protein
JC965_06750	COG1104	cysteine desulfurase activity
JC965_06755	COG0822	iron-sulfur transferase activity
JC965_06765	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JC965_06770	COG0443	Heat shock 70 kDa protein
JC965_06775	COG0633	Ferredoxin
JC965_06785	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JC965_06790	COG0105	UTP biosynthetic process
JC965_06795	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JC965_06805	COG1426	Protein conserved in bacteria
JC965_06815	COG0124	histidyl-tRNA synthetase
JC965_06820	COG2976	Protein conserved in bacteria
JC965_06825	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JC965_06830	COG1160	GTP binding
JC965_06835	COG1645	bacterial-type flagellum-dependent swarming motility
JC965_06840	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
JC965_06845	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JC965_06845	COG0047	phosphoribosylformylglycinamidine synthase activity
JC965_06850	COG1007	ATP synthesis coupled electron transport
JC965_06855	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JC965_06865	COG0713	ATP synthesis coupled electron transport
JC965_06870	COG0839	Belongs to the complex I subunit 6 family
JC965_06875	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JC965_06880	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JC965_06885	COG1034	ATP synthesis coupled electron transport
JC965_06900	COG0649	NAD binding
JC965_06900	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JC965_06905	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JC965_06910	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JC965_06915	COG1360	Flagellar Motor Protein
JC965_06920	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JC965_06940	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
JC965_06950	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
JC965_06960	COG0724	RNA recognition motif
JC965_06965	COG4989	oxidoreductase activity
JC965_06990	COG0745	RESPONSE REGULATOR receiver
JC965_07005	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
JC965_07010	COG0848	biopolymer transport protein
JC965_07015	COG0811	peptide transport
JC965_07020	COG0811	peptide transport
JC965_07030	COG2771	luxR family
JC965_07035	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JC965_07040	COG1349	DNA-binding transcription factor activity
JC965_07045	COG0745	RESPONSE REGULATOR receiver
JC965_07050	COG2205	protein histidine kinase activity
JC965_07060	COG4452	Inner membrane protein CreD
JC965_07065	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JC965_07070	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JC965_07075	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JC965_07080	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JC965_07085	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JC965_07090	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JC965_07095	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JC965_07105	COG0356	it plays a direct role in the translocation of protons across the membrane
JC965_07115	COG1475	DNA binding
JC965_07120	COG1192	Involved in chromosome partitioning
JC965_07125	COG0357	Ribosomal RNA small subunit methyltransferase G
JC965_07130	COG0445	tRNA wobble uridine modification
JC965_07135	COG0716	FMN binding
JC965_07140	COG4774	siderophore transport
JC965_07145	COG4615	Cyclic peptide transporter
JC965_07150	COG1120	ATPase activity
JC965_07155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JC965_07165	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JC965_07170	COG0706	membrane insertase activity
JC965_07175	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JC965_07180	COG0594	ribonuclease P activity
JC965_07185	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JC965_07190	COG1126	abc transporter atp-binding protein
JC965_07205	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JC965_07210	COG0592	DNA-directed DNA polymerase activity
JC965_07220	COG0187	DNA topoisomerase II activity
JC965_07230	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JC965_07235	COG0071	Belongs to the small heat shock protein (HSP20) family
JC965_07240	COG0071	Belongs to the small heat shock protein (HSP20) family
JC965_07245	COG3977	Valine--pyruvate aminotransferase
JC965_07260	COG2814	Major facilitator Superfamily
JC965_07265	COG0745	RESPONSE REGULATOR receiver
JC965_07270	COG2205	protein histidine kinase activity
JC965_07295	COG1611	Belongs to the LOG family
JC965_07300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JC965_07305	COG0473	3-isopropylmalate dehydrogenase activity
JC965_07315	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
JC965_07330	COG0583	DNA-binding transcription factor activity
JC965_07335	COG0840	transmembrane signaling receptor activity
JC965_07340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JC965_07355	COG1477	protein flavinylation
JC965_07360	COG2871	sodium ion transport
JC965_07365	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JC965_07370	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JC965_07375	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JC965_07380	COG1805	sodium ion transport
JC965_07385	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JC965_07390	COG0271	Belongs to the BolA IbaG family
JC965_07395	COG2813	Specifically methylates the guanine in position
JC965_07405	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JC965_07415	COG2211	Major facilitator Superfamily
JC965_07420	COG3248	Nucleoside-binding outer membrane protein
JC965_07425	COG1666	GTP binding
JC965_07430	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JC965_07440	COG0659	secondary active sulfate transmembrane transporter activity
JC965_07450	COG0745	RESPONSE REGULATOR receiver
JC965_07455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JC965_07460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JC965_07475	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JC965_07485	COG1151	hydroxylamine reductase activity
JC965_07490	COG0783	Belongs to the Dps family
JC965_07515	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JC965_07530	COG4221	oxidoreductase activity
JC965_07540	COG0415	Belongs to the DNA photolyase family
JC965_07545	COG0789	Transcriptional regulator
JC965_07550	COG3272	Protein of unknown function (DUF1722)
JC965_07575	COG0077	Prephenate dehydratase
JC965_07575	COG1605	Chorismate mutase
JC965_07605	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
JC965_07615	COG5377	YqaJ viral recombinase family
JC965_07635	COG0456	acetyltransferase
JC965_07670	COG0538	isocitrate dehydrogenase activity
JC965_07680	COG3048	D-serine ammonia-lyase activity
JC965_07685	COG0583	DNA-binding transcription factor activity
JC965_07690	COG2916	Histone family protein nucleoid-structuring protein H-NS
JC965_07695	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JC965_07700	COG2375	cellular response to nickel ion
JC965_07705	COG1538	Outer membrane efflux protein
JC965_07710	COG1136	(ABC) transporter
JC965_07710	COG0577	efflux transmembrane transporter activity
JC965_07715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JC965_07725	COG0497	DNA recombination
JC965_07735	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JC965_07740	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JC965_07745	COG0443	Heat shock 70 kDa protein
JC965_07750	COG0484	heat shock protein binding
JC965_07780	COG1285	pathogenesis
JC965_07820	COG0095	Lipoate-protein ligase
JC965_07840	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JC965_07845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JC965_07870	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JC965_07875	COG0527	aspartate kinase activity
JC965_07880	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JC965_07915	COG1686	Belongs to the peptidase S11 family
JC965_07920	COG0586	Pfam SNARE associated Golgi protein
JC965_07925	COG1253	flavin adenine dinucleotide binding
JC965_07930	COG0525	valine-tRNA ligase activity
JC965_07935	COG2927	DNA polymerase III (CHI subunit)
JC965_07940	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JC965_07945	COG0795	lipopolysaccharide-transporting ATPase activity
JC965_07950	COG0795	lipopolysaccharide-transporting ATPase activity
JC965_08115	COG4695	Portal protein
JC965_08210	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JC965_08225	COG4974	Belongs to the 'phage' integrase family
JC965_08230	COG4974	Belongs to the 'phage' integrase family
JC965_08245	COG0456	acetyltransferase
JC965_08255	COG1854	S-ribosylhomocysteine lyase activity
JC965_08270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JC965_08270	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JC965_08335	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JC965_08340	COG1047	Peptidyl-prolyl cis-trans
JC965_08345	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JC965_08350	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JC965_08355	COG0196	riboflavin kinase activity
JC965_08360	COG0728	peptidoglycan biosynthetic process
JC965_08365	COG0268	Binds directly to 16S ribosomal RNA
JC965_08370	COG0640	Transcriptional regulator
JC965_08375	COG0583	DNA-binding transcription factor activity
JC965_08385	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JC965_08390	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JC965_08395	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JC965_08405	COG1051	belongs to the nudix hydrolase family
JC965_08420	COG0335	large ribosomal subunit rRNA binding
JC965_08425	COG0336	Belongs to the RNA methyltransferase TrmD family
JC965_08430	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JC965_08435	COG0228	four-way junction DNA binding
JC965_08440	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JC965_08445	COG4137	Cytochrome C assembly protein
JC965_08450	COG4536	flavin adenine dinucleotide binding
JC965_08460	COG1017	nitric oxide dioxygenase activity
JC965_08460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JC965_08465	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
JC965_08470	COG0039	L-malate dehydrogenase activity
JC965_08475	COG4160	amino acid transport
JC965_08480	COG4215	(ABC) transporter
JC965_08485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JC965_08490	COG1126	abc transporter atp-binding protein
JC965_08495	COG1438	arginine binding
JC965_08500	COG2837	iron assimilation
JC965_08505	COG3842	ATPase activity
JC965_08520	COG0347	Belongs to the P(II) protein family
JC965_08535	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JC965_08540	COG0583	DNA-binding transcription factor activity
JC965_08585	COG1242	4 iron, 4 sulfur cluster binding
JC965_08590	COG0069	glutamate synthase activity
JC965_08590	COG0067	glutamate synthase
JC965_08590	COG0070	glutamate synthase
JC965_08595	COG0493	'glutamate synthase
JC965_08615	COG4104	PAAR repeat-containing protein
JC965_08625	COG0513	Belongs to the DEAD box helicase family
JC965_08655	COG3706	GGDEF domain
JC965_08660	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JC965_08665	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JC965_08670	COG0505	Belongs to the CarA family
JC965_08675	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JC965_08685	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JC965_08690	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JC965_08695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JC965_08700	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JC965_08705	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JC965_08710	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
JC965_08715	COG4139	cobalamin transport
JC965_08740	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
JC965_08750	COG0023	Translation Initiation Factor
JC965_08755	COG2119	membrane
JC965_08780	COG0675	Transposase, IS605 OrfB family
JC965_08790	COG1595	DNA-templated transcription, initiation
JC965_08800	COG2067	long-chain fatty acid transport protein
JC965_08805	COG2067	long-chain fatty acid transport protein
JC965_08810	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JC965_08825	COG1301	dicarboxylic acid transport
JC965_08830	COG3123	guanosine phosphorylase activity
JC965_08835	COG1760	l-serine dehydratase
JC965_08840	COG1760	l-serine dehydratase
JC965_08850	COG0814	amino acid
JC965_08865	COG0825	malonyl-CoA metabolic process
JC965_08875	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JC965_08880	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JC965_08885	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JC965_08890	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JC965_08895	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JC965_08910	COG0750	zinc metalloprotease
JC965_08915	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JC965_08920	COG0575	Belongs to the CDS family
JC965_08925	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JC965_08930	COG0233	cytoplasmic translational termination
JC965_08935	COG0528	UMP kinase activity
JC965_08940	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JC965_08945	COG0052	Belongs to the universal ribosomal protein uS2 family
JC965_08950	COG0024	Methionine aminopeptidase
JC965_08955	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
JC965_08960	COG2171	N-acyltransferase activity
JC965_08970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JC965_08970	COG1263	PTS System
JC965_08995	COG0564	pseudouridine synthase activity
JC965_09000	COG3098	single-species biofilm formation
JC965_09030	COG0521	Mo-molybdopterin cofactor biosynthetic process
JC965_09050	COG2313	pseudouridylate synthase activity
JC965_09055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JC965_09060	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JC965_09060	COG2146	nitrite reductase [NAD(P)H] activity
JC965_09065	COG2146	nitrite reductase [NAD(P)H] activity
JC965_09065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JC965_09070	COG1116	anion transmembrane transporter activity
JC965_09075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JC965_09080	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JC965_09080	COG1116	anion transmembrane transporter activity
JC965_09090	COG1648	precorrin-2 dehydrogenase activity
JC965_09090	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JC965_09095	COG0243	molybdopterin cofactor binding
JC965_09120	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JC965_09135	COG1073	alpha beta
JC965_09140	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
JC965_09145	COG2195	Cleaves the N-terminal amino acid of tripeptides
JC965_09150	COG4608	Belongs to the ABC transporter superfamily
JC965_09155	COG0444	Belongs to the ABC transporter superfamily
JC965_09165	COG4239	(ABC) transporter, permease
JC965_09170	COG4174	ABC transporter (Permease)
JC965_09175	COG4206	TonB-dependent receptor
JC965_09185	COG0811	peptide transport
JC965_09190	COG0811	peptide transport
JC965_09195	COG0848	biopolymer transport protein
JC965_09245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JC965_09250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JC965_09255	COG0840	transmembrane signaling receptor activity
JC965_09260	COG3335	DDE superfamily endonuclease
JC965_09280	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JC965_09290	COG1280	lysine exporter protein (LysE YggA)
JC965_09295	COG0826	peptidase U32
JC965_09305	COG3813	Protein conserved in bacteria
JC965_09325	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JC965_09350	COG0300	oxidoreductase activity
JC965_09365	COG0697	spore germination
JC965_09370	COG2610	gluconate transmembrane transporter activity
JC965_09375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JC965_09380	COG3622	Belongs to the hyi family
JC965_09385	COG0235	Class ii aldolase
JC965_09395	COG2084	Dehydrogenase
JC965_09400	COG1349	DNA-binding transcription factor activity
JC965_09410	COG2133	pyrroloquinoline quinone binding
JC965_09445	COG3177	Filamentation induced by cAMP protein fic
JC965_09460	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JC965_09465	COG0514	ATP-dependent DNA helicase (RecQ)
JC965_09485	COG0514	ATP-dependent DNA helicase (RecQ)
JC965_09490	COG1484	DNA-dependent DNA replication
JC965_09515	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JC965_09520	COG0045	succinate-CoA ligase (ADP-forming) activity
JC965_09525	COG0508	dehydrogenase complex catalyzes the overall conversion of
JC965_09530	COG0567	Dehydrogenase, E1 component
JC965_09545	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
JC965_09550	COG2009	succinate dehydrogenase
JC965_09570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JC965_09575	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
JC965_09575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JC965_09585	COG3069	C4-dicarboxylate transmembrane transporter activity
JC965_09600	COG1451	nucleotide metabolic process
JC965_09615	COG0254	rRNA binding
JC965_09620	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JC965_09630	COG1172	Belongs to the binding-protein-dependent transport system permease family
JC965_09635	COG1129	ABC transporter
JC965_09640	COG1879	ABC-type sugar transport system periplasmic component
JC965_09645	COG1069	ribulokinase activity
JC965_09655	COG2160	L-arabinose isomerase activity
JC965_09660	COG0583	DNA-binding transcription factor activity
JC965_09665	COG0436	Aminotransferase
JC965_09670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JC965_09685	COG0392	lysyltransferase activity
JC965_09685	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JC965_09690	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JC965_09695	COG2925	Exonuclease
JC965_09750	COG2203	Gaf domain
JC965_09750	COG3706	GGDEF domain
JC965_09750	COG5001	Diguanylate cyclase
JC965_09750	COG4251	negative regulation of phosphorylation
JC965_09770	COG0814	amino acid
JC965_09775	COG0814	amino acid
JC965_09780	COG3033	Beta-eliminating lyase
JC965_09790	COG0348	domain, Protein
JC965_09800	COG0446	pyridine nucleotide-disulphide oxidoreductase
JC965_09805	COG1773	rubredoxin
JC965_09805	COG0426	domain, Protein
JC965_09810	COG3604	Transcriptional regulator
JC965_09815	COG1609	Transcriptional regulator
JC965_09855	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JC965_09870	COG2960	long-chain fatty acid transporting porin activity
JC965_09880	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JC965_09895	COG3118	belongs to the thioredoxin family
JC965_09900	COG0513	Belongs to the DEAD box helicase family
JC965_09905	COG0248	Ppx GppA phosphatase
JC965_09915	COG0742	ribosomal rna small subunit methyltransferase
JC965_09935	COG0084	hydrolase, TatD family'
JC965_09940	COG0805	protein transport
JC965_09945	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JC965_09950	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JC965_09955	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JC965_09960	COG3165	ubiquinone biosynthetic process from chorismate
JC965_09970	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JC965_09975	COG0402	S-adenosylhomocysteine deaminase activity
JC965_10005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JC965_10010	COG1131	(ABC) transporter
JC965_10015	COG0842	Transport permease protein
JC965_10020	COG0842	Transport permease protein
JC965_10025	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JC965_10035	COG2116	formate transmembrane transporter activity
JC965_10040	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JC965_10040	COG1648	precorrin-2 dehydrogenase activity
JC965_10045	COG2239	Acts as a magnesium transporter
JC965_10050	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JC965_10055	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JC965_10065	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JC965_10075	COG0514	ATP-dependent DNA helicase (RecQ)
JC965_10080	COG2050	protein possibly involved in aromatic compounds catabolism
JC965_10095	COG2258	MOSC domain
JC965_10100	COG1177	transmembrane transport
JC965_10105	COG1176	ABC-type spermidine putrescine transport system, permease component I
JC965_10110	COG3842	ATPase activity
JC965_10130	COG0174	glutamine synthetase
JC965_10150	COG3045	CreA protein
JC965_10155	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JC965_10160	COG0443	Heat shock 70 kDa protein
JC965_10175	COG0366	Alpha amylase catalytic
JC965_10190	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JC965_10195	COG0745	RESPONSE REGULATOR receiver
JC965_10205	COG2205	protein histidine kinase activity
JC965_10215	COG0281	malic enzyme
JC965_10220	COG0702	epimerase
JC965_10235	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JC965_10240	COG0328	RNA-DNA hybrid ribonuclease activity
JC965_10245	COG2226	methyltransferase
JC965_10250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JC965_10255	COG1388	LysM domain
JC965_10255	COG0741	lytic transglycosylase activity
JC965_10270	COG1607	acyl-coa hydrolase
JC965_10285	COG0741	lytic transglycosylase activity
JC965_10295	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JC965_10315	COG2911	Protein conserved in bacteria
JC965_10320	COG0729	surface antigen
JC965_10330	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JC965_10340	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JC965_10345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JC965_10350	COG4134	Bacterial extracellular solute-binding protein
JC965_10360	COG4136	ATPase activity
JC965_10365	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JC965_10370	COG2951	lytic endotransglycosylase activity
JC965_10375	COG1846	Transcriptional regulator
JC965_10385	COG0033	Phosphoglucomutase
JC965_10390	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
JC965_10395	COG0596	Alpha beta hydrolase
JC965_10410	COG0716	FMN binding
JC965_10420	COG0735	belongs to the Fur family
JC965_10425	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JC965_10435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JC965_10435	COG2190	(PTS) system
JC965_10435	COG1263	PTS System
JC965_10440	COG0363	glucosamine-6-phosphate deaminase activity
JC965_10445	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JC965_10450	COG1846	Transcriptional regulator
JC965_10450	COG1940	carbohydrate kinase activity
JC965_10470	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
JC965_10475	COG2252	PERMEase
JC965_10480	COG2376	Dihydroxyacetone kinase
JC965_10485	COG1461	Dihydroxyacetone kinase
JC965_10500	COG0583	DNA-binding transcription factor activity
JC965_10505	COG2957	Belongs to the agmatine deiminase family
JC965_10520	COG2957	Belongs to the agmatine deiminase family
JC965_10530	COG0628	permease
JC965_10535	COG0494	nUDIX hydrolase
JC965_10555	COG0753	catalase activity
JC965_10560	COG0456	acetyltransferase
JC965_10590	COG3842	ATPase activity
JC965_10600	COG1175	transmembrane transport
JC965_10625	COG0583	DNA-binding transcription factor activity
JC965_10635	COG1741	Belongs to the pirin family
JC965_10640	COG2259	Doxx family
JC965_10645	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JC965_10650	COG1074	ATP-dependent DNA helicase activity
JC965_10655	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JC965_10680	COG1301	dicarboxylic acid transport
JC965_10685	COG2877	3-deoxy-8-phosphooctulonate synthase activity
JC965_10690	COG2912	Transglutaminase-like superfamily
JC965_10705	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JC965_10710	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JC965_10715	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
JC965_10720	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JC965_10730	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JC965_10735	COG0193	aminoacyl-tRNA hydrolase activity
JC965_10740	COG0012	GTP binding
JC965_10785	COG0490	domain, Protein
JC965_10785	COG0471	metal ion transport
JC965_10810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JC965_10825	COG1012	belongs to the aldehyde dehydrogenase family
JC965_10835	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JC965_10850	COG0180	Tryptophanyl-tRNA synthetase
JC965_10855	COG0546	phosphoglycolate phosphatase activity
JC965_10860	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JC965_10865	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JC965_10875	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JC965_10880	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JC965_10910	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JC965_10915	COG0583	DNA-binding transcription factor activity
JC965_10930	COG0583	DNA-binding transcription factor activity
JC965_10950	COG1253	flavin adenine dinucleotide binding
JC965_10955	COG1902	pentaerythritol trinitrate reductase activity
JC965_10960	COG0604	alcohol dehydrogenase
JC965_10965	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JC965_10970	COG0647	UMP catabolic process
JC965_10980	COG0367	asparagine synthase
JC965_10995	COG0625	glutathione transferase activity
JC965_11005	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
JC965_11020	COG0564	pseudouridine synthase activity
JC965_11035	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JC965_11075	COG0670	Belongs to the BI1 family
JC965_11080	COG1289	transmembrane transporter activity
JC965_11085	COG2920	part of a sulfur-relay system
JC965_11090	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
JC965_11095	COG0285	dihydrofolate synthase activity
JC965_11100	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JC965_11105	COG0101	tRNA pseudouridine synthase activity
JC965_11115	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JC965_11120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JC965_11145	COG0840	transmembrane signaling receptor activity
JC965_11150	COG0513	Belongs to the DEAD box helicase family
JC965_11185	COG0457	Tetratricopeptide repeat
JC965_11185	COG3118	belongs to the thioredoxin family
JC965_11195	COG1215	transferase activity, transferring glycosyl groups
JC965_11220	COG1448	Aminotransferase
JC965_11235	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JC965_11240	COG1328	CTP reductase activity
JC965_11265	COG0840	transmembrane signaling receptor activity
JC965_11270	COG3397	chitin binding
JC965_11275	COG0583	DNA-binding transcription factor activity
JC965_11280	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JC965_11285	COG4208	sulfate ABC transporter
JC965_11290	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
JC965_11300	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JC965_11320	COG1929	Belongs to the glycerate kinase type-1 family
JC965_11325	COG2610	gluconate transmembrane transporter activity
JC965_11330	COG3835	regulator
JC965_11335	COG3112	Uncharacterised protein family (UPF0231)
JC965_11355	COG1872	DUF167
JC965_11360	COG0762	integral membrane protein
JC965_11365	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JC965_11370	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JC965_11385	COG3022	response to hydroperoxide
JC965_11390	COG0513	Belongs to the DEAD box helicase family
JC965_11395	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JC965_11415	COG0735	belongs to the Fur family
JC965_11420	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JC965_11435	COG0776	regulation of translation
JC965_11440	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
JC965_11450	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JC965_11465	COG0560	Phosphoserine phosphatase
JC965_11475	COG5002	protein histidine kinase activity
JC965_11475	COG3447	MASE1 domain protein
JC965_11475	COG5001	Diguanylate cyclase
JC965_11480	COG4520	surface antigen
JC965_11490	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JC965_11495	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JC965_11500	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JC965_11510	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JC965_11515	COG0084	hydrolase, TatD family'
JC965_11520	COG2165	general secretion pathway protein
JC965_11535	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JC965_11540	COG0004	ammonium transporteR
JC965_11560	COG1263	PTS System
JC965_11560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JC965_11585	COG0675	Transposase, IS605 OrfB family
JC965_11590	COG0675	Transposase, IS605 OrfB family
JC965_11595	COG4657	Part of a membrane complex involved in electron transport
JC965_11600	COG2878	Part of a membrane complex involved in electron transport
JC965_11605	COG4656	Part of a membrane complex involved in electron transport
JC965_11610	COG4658	electron transport chain
JC965_11615	COG4659	FMN binding
JC965_11620	COG4660	Part of a membrane complex involved in electron transport
JC965_11625	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JC965_11630	COG0346	lactoylglutathione lyase activity
JC965_11650	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JC965_11660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JC965_11665	COG1086	Polysaccharide biosynthesis protein
JC965_11670	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JC965_11680	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
JC965_11685	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JC965_11700	COG2089	acid synthase
JC965_11740	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JC965_11760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JC965_11760	COG0301	tRNA thio-modification
JC965_11770	COG4953	penicillin-binding protein 1C
JC965_11775	COG2373	Large extracellular alpha-helical protein
JC965_11800	COG0140	phosphoribosyl-ATP diphosphatase activity
JC965_11800	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JC965_11805	COG0107	imidazoleglycerol-phosphate synthase activity
JC965_11810	COG0784	Response regulator, receiver
JC965_11810	COG2198	Histidine kinase
JC965_11810	COG2205	protein histidine kinase activity
JC965_11815	COG2199	diguanylate cyclase activity
JC965_11820	COG3437	response regulator, receiver
JC965_11825	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JC965_11830	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JC965_11835	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JC965_11835	COG0131	Imidazoleglycerol-phosphate dehydratase
JC965_11840	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JC965_11845	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JC965_11850	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JC965_11860	COG1199	ATP-dependent helicase activity
JC965_11865	COG1214	PFAM Peptidase M22, glycoprotease
JC965_11875	COG0596	Alpha beta hydrolase
JC965_11880	COG0318	PFAM AMP-dependent synthetase and ligase
JC965_11895	COG0697	spore germination
JC965_11905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JC965_11910	COG2832	Protein of unknown function (DUF454)
JC965_11915	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JC965_11925	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JC965_11930	COG0583	DNA-binding transcription factor activity
JC965_11940	COG3314	Sporulation integral membrane protein YlbJ
JC965_11945	COG2197	response regulator
JC965_11950	COG0617	tRNA 3'-terminal CCA addition
JC965_11950	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JC965_11950	COG0517	IMP dehydrogenase activity
JC965_11955	COG1643	Atp-dependent helicase
JC965_11975	COG0457	Tetratricopeptide repeat
JC965_11985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JC965_11990	COG1138	Cytochrome C-type biogenesis protein
JC965_11995	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
JC965_12000	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JC965_12005	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JC965_12010	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JC965_12025	COG0835	chemotaxis
JC965_12035	COG1192	Involved in chromosome partitioning
JC965_12040	COG1360	Flagellar Motor Protein
JC965_12045	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JC965_12050	COG2201	protein-glutamate methylesterase activity
JC965_12055	COG2198	Histidine kinase
JC965_12055	COG0784	Response regulator, receiver
JC965_12055	COG0643	Histidine kinase
JC965_12060	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
JC965_12085	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JC965_12095	COG1684	flagellar biosynthetic protein fliR
JC965_12150	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JC965_12160	COG1677	Flagellar hook-basal body complex protein FliE
JC965_12170	COG1393	Belongs to the ArsC family
JC965_12175	COG0798	PFAM Bile acid sodium symporter
JC965_12180	COG0640	Transcriptional regulator
JC965_12195	COG2194	sulfuric ester hydrolase activity
JC965_12200	COG0217	transcriptional regulatory protein
JC965_12205	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JC965_12210	COG1801	Protein of unknown function DUF72
JC965_12215	COG4106	trans-aconitate 2-methyltransferase activity
JC965_12220	COG0500	methyltransferase
JC965_12240	COG0583	DNA-binding transcription factor activity
JC965_12245	COG0791	NLP P60 protein
JC965_12260	COG1309	transcriptional regulator
JC965_12270	COG1454	alcohol dehydrogenase
JC965_12295	COG0534	Mate efflux family protein
JC965_12305	COG2841	Protein conserved in bacteria
JC965_12310	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JC965_12310	COG1013	pyruvate-flavodoxin oxidoreductase activity
JC965_12310	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JC965_12310	COG0674	pyruvate-flavodoxin oxidoreductase activity
JC965_12320	COG3217	Mosc domain protein beta barrel domain protein
JC965_12320	COG0633	Ferredoxin
JC965_12320	COG0633	Ferredoxin
JC965_12320	COG3217	Mosc domain protein beta barrel domain protein
JC965_12325	COG0501	Belongs to the peptidase M48B family
JC965_12330	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JC965_12335	COG2226	methyltransferase
JC965_12335	COG1073	alpha beta
JC965_12340	COG0156	8-amino-7-oxononanoate synthase activity
JC965_12345	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JC965_12365	COG0017	Asparaginyl-tRNA synthetase
JC965_12370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JC965_12370	COG1042	CoA-binding domain protein
JC965_12370	COG0045	succinate-CoA ligase (ADP-forming) activity
JC965_12380	COG0583	DNA-binding transcription factor activity
JC965_12385	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JC965_12390	COG0166	Belongs to the GPI family
JC965_12400	COG0668	transmembrane transport
JC965_12410	COG1309	transcriptional regulator
JC965_12415	COG0756	dUTP diphosphatase activity
JC965_12420	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JC965_12425	COG2003	Belongs to the UPF0758 family
JC965_12430	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JC965_12435	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JC965_12445	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JC965_12450	COG2990	Protein conserved in bacteria
JC965_12455	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JC965_12460	COG0859	PFAM glycosyl transferase family 9
JC965_12465	COG0463	Glycosyl transferase, family 2
JC965_12470	COG0859	PFAM glycosyl transferase family 9
JC965_12475	COG1519	Transferase
JC965_12510	COG1857	crispr-associated protein
JC965_12525	COG1518	maintenance of DNA repeat elements
JC965_12530	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JC965_12545	COG2964	Protein conserved in bacteria
JC965_12550	COG3681	Belongs to the UPF0597 family
JC965_12555	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JC965_12560	COG0564	pseudouridine synthase activity
JC965_12570	COG0542	response to heat
JC965_12575	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JC965_12580	COG2502	aspartate--ammonia ligase
JC965_12585	COG1522	sequence-specific DNA binding
JC965_12595	COG0517	IMP dehydrogenase activity
JC965_12595	COG0516	GMP reductase activity
JC965_12615	COG2205	protein histidine kinase activity
JC965_12625	COG2204	response regulator
JC965_12635	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JC965_12670	COG0243	molybdopterin cofactor binding
JC965_12675	COG3005	denitrification pathway
JC965_12680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JC965_12685	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JC965_12690	COG0569	domain protein
JC965_12695	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JC965_12720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JC965_12725	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JC965_12735	COG1132	(ABC) transporter
JC965_12740	COG1132	(ABC) transporter
JC965_12750	COG3118	belongs to the thioredoxin family
JC965_12755	COG0471	metal ion transport
JC965_12765	COG0058	SHG alpha-glucan phosphorylase activity
JC965_12790	COG0494	nUDIX hydrolase
JC965_12795	COG0814	amino acid
JC965_12800	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
JC965_12805	COG0514	ATP-dependent DNA helicase (RecQ)
JC965_12810	COG2766	serine protein kinase
JC965_12815	COG2718	Belongs to the UPF0229 family
JC965_12820	COG2719	SpoVR family
JC965_12825	COG2186	Transcriptional regulator
JC965_12830	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JC965_12835	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JC965_12840	COG0586	Pfam SNARE associated Golgi protein
JC965_12850	COG0556	nucleotide-excision repair
JC965_12860	COG0569	domain protein
JC965_12860	COG2985	domain, Protein
JC965_12870	COG0488	(ABC) transporter
JC965_12875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JC965_12880	COG0776	regulation of translation
JC965_12885	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JC965_12890	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JC965_12895	COG0740	serine-type endopeptidase activity
JC965_12900	COG0544	peptidyl-prolyl cis-trans isomerase activity
JC965_12910	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
JC965_12915	COG4591	ABC-type transport system involved in lipoprotein release permease component
JC965_12920	COG1136	(ABC) transporter
JC965_12925	COG4591	ABC-type transport system involved in lipoprotein release permease component
JC965_12935	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JC965_12940	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
JC965_12955	COG0697	spore germination
JC965_12965	COG2062	phosphohistidine phosphatase, SixA
JC965_12985	COG1846	Transcriptional regulator
JC965_13000	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JC965_13000	COG0519	Catalyzes the synthesis of GMP from XMP
JC965_13005	COG0517	IMP dehydrogenase activity
JC965_13005	COG0516	GMP reductase activity
JC965_13020	COG2926	Belongs to the UPF0265 family
JC965_13030	COG3028	Belongs to the UPF0307 family
JC965_13035	COG0312	modulator of DNA gyrase
JC965_13040	COG3071	HemY protein
JC965_13045	COG2959	enzyme of heme biosynthesis
JC965_13055	COG0181	hydroxymethylbilane synthase activity
JC965_13060	COG3072	Adenylate cyclase
JC965_13065	COG0400	carboxylic ester hydrolase activity
JC965_13070	COG1965	Belongs to the frataxin family
JC965_13080	COG0019	diaminopimelate decarboxylase activity
JC965_13085	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JC965_13100	COG1011	Hydrolase
JC965_13110	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JC965_13115	COG0561	phosphatase activity
JC965_13130	COG1988	membrane-bound metal-dependent
JC965_13135	COG1546	Belongs to the CinA family
JC965_13135	COG1058	Belongs to the CinA family
JC965_13140	COG1418	mRNA catabolic process
JC965_13145	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JC965_13155	COG1522	sequence-specific DNA binding
JC965_13195	COG1484	DNA-dependent DNA replication
JC965_13200	COG3706	GGDEF domain
JC965_13205	COG0557	exoribonuclease II activity
JC965_13230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JC965_13240	COG2153	protein acetylation
JC965_13250	COG1914	H( )-stimulated, divalent metal cation uptake system
JC965_13255	COG0360	Binds together with S18 to 16S ribosomal RNA
JC965_13260	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JC965_13265	COG0359	binds to the 23S rRNA
JC965_13305	COG1238	metal cluster binding
JC965_13310	COG0612	Peptidase, M16
JC965_13315	COG2918	glutathione biosynthetic process
JC965_13320	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JC965_13325	COG1027	Aspartate ammonia-lyase
JC965_13330	COG3030	protein affecting phage T7 exclusion by the F plasmid
JC965_13335	COG0534	Mate efflux family protein
JC965_13340	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JC965_13345	COG0459	protein refolding
JC965_13365	COG0564	pseudouridine synthase activity
JC965_13370	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JC965_13385	COG2226	methyltransferase
JC965_13395	COG1765	OsmC-like protein
JC965_13410	COG3954	Phosphoribulokinase
JC965_13415	COG3089	Belongs to the UPF0270 family
JC965_13420	COG5001	Diguanylate cyclase
JC965_13420	COG4251	negative regulation of phosphorylation
JC965_13420	COG3706	GGDEF domain
JC965_13420	COG2203	Gaf domain
JC965_13425	COG0429	hydrolase of the alpha beta-hydrolase fold
JC965_13430	COG0784	Response regulator, receiver
JC965_13430	COG0835	chemotaxis
JC965_13440	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
JC965_13445	COG1047	Peptidyl-prolyl cis-trans
JC965_13450	COG2900	Belongs to the SlyX family
JC965_13460	COG0545	Peptidyl-prolyl cis-trans isomerase
JC965_13465	COG2204	response regulator
JC965_13490	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JC965_13495	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
JC965_13510	COG3132	Protein of unknown function, DUF480
JC965_13535	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JC965_13550	COG1278	Cold shock
JC965_13595	COG1289	transmembrane transporter activity
JC965_13600	COG1566	PFAM secretion protein HlyD family protein
JC965_13615	COG1051	belongs to the nudix hydrolase family
JC965_13620	COG3150	esterase
JC965_13630	COG3151	Protein conserved in bacteria
JC965_13635	COG0494	nUDIX hydrolase
JC965_13640	COG1538	Outer membrane efflux protein
JC965_13645	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JC965_13645	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JC965_13650	COG1560	Kdo2-lipid A biosynthetic process
JC965_13665	COG2771	luxR family
JC965_13670	COG3916	Acyl-homoserine-lactone synthase
JC965_13680	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
JC965_13685	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JC965_13685	COG2213	PTS system mannitol-specific
JC965_13690	COG0246	Mannitol dehydrogenase
JC965_13695	COG3722	fumarate hydratase activity
JC965_13720	COG1671	Belongs to the UPF0178 family
JC965_13745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JC965_13755	COG1028	Short-chain dehydrogenase reductase Sdr
JC965_13760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JC965_13765	COG1535	isochorismatase
JC965_13765	COG3433	isochorismatase activity
JC965_13770	COG1021	2,3-dihydroxybenzoate-AMP ligase
JC965_13795	COG5001	Diguanylate cyclase
JC965_13795	COG3300	MHYT domain
JC965_13810	COG0840	transmembrane signaling receptor activity
JC965_13815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JC965_13820	COG3788	relative of glutathione S-transferase, MAPEG superfamily
JC965_13825	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JC965_13830	COG0563	adenylate kinase activity
JC965_13835	COG0326	Molecular chaperone. Has ATPase activity
JC965_13840	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JC965_13860	COG1280	lysine exporter protein (LysE YggA)
JC965_13865	COG2223	nitrite transmembrane transporter activity
JC965_13870	COG2081	HI0933 family
JC965_13875	COG1528	Iron-storage protein
JC965_13880	COG3706	GGDEF domain
JC965_13885	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JC965_13890	COG0589	response to stress
JC965_13930	COG3642	lipopolysaccharide core region biosynthetic process
JC965_13935	COG0859	PFAM glycosyl transferase family 9
JC965_13945	COG1758	RNA polymerase activity
JC965_13950	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JC965_13955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JC965_13965	COG2267	carboxylic ester hydrolase activity
JC965_13970	COG0561	phosphatase activity
JC965_14005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JC965_14010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JC965_14015	COG4191	Histidine kinase
JC965_14015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JC965_14020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JC965_14060	COG1132	(ABC) transporter
JC965_14070	COG2897	thiosulfate sulfurtransferase activity
JC965_14075	COG2066	Belongs to the glutaminase family
JC965_14080	COG3171	Protein conserved in bacteria
JC965_14085	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JC965_14090	COG4935	Belongs to the peptidase S8 family
JC965_14090	COG2234	aminopeptidase activity
JC965_14095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JC965_14100	COG2200	EAL domain
JC965_14105	COG1090	epimerase
JC965_14110	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
JC965_14115	COG4181	ATPase activity
JC965_14120	COG2755	lipolytic protein G-D-S-L family
JC965_14125	COG0784	Response regulator, receiver
JC965_14125	COG0835	chemotaxis
JC965_14135	COG0516	GMP reductase activity
JC965_14135	COG0517	IMP dehydrogenase activity
JC965_14140	COG0488	(ABC) transporter
JC965_14150	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
JC965_14205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JC965_14210	COG0444	Belongs to the ABC transporter superfamily
JC965_14215	COG4608	Belongs to the ABC transporter superfamily
JC965_14225	COG2971	BadF BadG BcrA BcrD
JC965_14235	COG0840	transmembrane signaling receptor activity
JC965_14255	COG3724	N-succinylarginine dihydrolase activity
JC965_14260	COG0616	signal peptide processing
JC965_14265	COG1028	Short-chain dehydrogenase reductase Sdr
JC965_14270	COG0583	DNA-binding transcription factor activity
JC965_14280	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JC965_14290	COG0583	DNA-binding transcription factor activity
JC965_14295	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JC965_14300	COG1881	PFAM PEBP family protein
JC965_14310	COG3408	Glycogen debranching enzyme
JC965_14310	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
JC965_14325	COG1288	antiporter activity
JC965_14330	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JC965_14370	COG3250	beta-galactosidase activity
JC965_14375	COG1609	Transcriptional regulator
JC965_14380	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JC965_14390	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JC965_14395	COG2017	converts alpha-aldose to the beta-anomer
JC965_14405	COG1968	undecaprenyl-diphosphatase activity
JC965_14410	COG3806	Anti-sigma factor
JC965_14415	COG1595	DNA-templated transcription, initiation
JC965_14435	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JC965_14440	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JC965_14470	COG0110	maltose O-acetyltransferase activity
JC965_14485	COG3932	Exopolysaccharide synthesis, ExoD
JC965_14505	COG1733	regulation of RNA biosynthetic process
JC965_14530	COG2226	methyltransferase
JC965_14540	COG1494	fructose-1,6-bisphosphatase
JC965_14550	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JC965_14555	COG5007	Belongs to the BolA IbaG family
JC965_14565	COG2854	intermembrane phospholipid transfer
JC965_14570	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JC965_14575	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JC965_14580	COG1127	ABC transporter
JC965_14585	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JC965_14585	COG0517	IMP dehydrogenase activity
JC965_14590	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JC965_14600	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
JC965_14605	COG1137	ATPase activity
JC965_14610	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JC965_14620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JC965_14625	COG1660	Displays ATPase and GTPase activities
JC965_14630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JC965_14640	COG0675	Transposase, IS605 OrfB family
JC965_14645	COG1960	acyl-CoA dehydrogenase activity
JC965_14650	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JC965_14655	COG0121	glutamine amidotransferase
JC965_14665	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JC965_14690	COG2197	response regulator
JC965_14695	COG3850	Histidine kinase
JC965_14700	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JC965_14705	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
JC965_14705	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JC965_14715	COG0243	molybdopterin cofactor binding
JC965_14720	COG0437	4 iron, 4 sulfur cluster binding
JC965_14725	COG0348	domain, Protein
JC965_14735	COG3005	denitrification pathway
JC965_14740	COG0521	Mo-molybdopterin cofactor biosynthetic process
JC965_14745	COG0315	cyclic pyranopterin monophosphate synthase activity
JC965_14750	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JC965_14755	COG0314	molybdopterin synthase activity
JC965_14770	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JC965_14775	COG2267	carboxylic ester hydrolase activity
JC965_14780	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JC965_14785	COG0303	'Molybdopterin
JC965_14790	COG0302	gtp cyclohydrolase
JC965_14805	COG3181	Tripartite tricarboxylate transporter family receptor
JC965_14820	COG4565	transcriptional regulatory protein
JC965_14830	COG1940	carbohydrate kinase activity
JC965_14830	COG1846	Transcriptional regulator
JC965_14840	COG3012	SEC-C Motif Domain Protein
JC965_14845	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JC965_14850	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
JC965_14855	COG0247	lactate metabolic process
JC965_14865	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
JC965_14870	COG0437	4 iron, 4 sulfur cluster binding
JC965_14875	COG3301	Polysulphide reductase, NrfD
JC965_14880	COG1138	Cytochrome C-type biogenesis protein
JC965_14885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JC965_14890	COG4235	cytochrome complex assembly
JC965_14890	COG3088	subunit of a heme lyase
JC965_14905	COG3046	protein related to deoxyribodipyrimidine photolyase
JC965_14910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JC965_14915	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JC965_14915	COG0617	tRNA 3'-terminal CCA addition
JC965_14915	COG0517	IMP dehydrogenase activity
JC965_14935	COG3300	MHYT domain
JC965_14935	COG5001	Diguanylate cyclase
JC965_14940	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JC965_14970	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JC965_14975	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JC965_14980	COG0539	negative regulation of cytoplasmic translation
JC965_14985	COG0776	regulation of translation
JC965_14995	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
JC965_15015	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JC965_15020	COG0602	queuosine metabolic process
JC965_15025	COG3530	Putative quorum-sensing-regulated virulence factor
JC965_15030	COG2096	Adenosyltransferase
JC965_15035	COG2916	Histone family protein nucleoid-structuring protein H-NS
JC965_15040	COG1757	Na H antiporter
JC965_15045	COG1435	thymidine kinase activity
JC965_15070	COG4974	Belongs to the 'phage' integrase family
JC965_15080	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JC965_15085	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JC965_15085	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JC965_15090	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
JC965_15095	COG3074	FtsZ-dependent cytokinesis
JC965_15105	COG1045	serine acetyltransferase
JC965_15115	COG0745	RESPONSE REGULATOR receiver
JC965_15120	COG2205	protein histidine kinase activity
JC965_15125	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JC965_15130	COG0534	Mate efflux family protein
JC965_15145	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JC965_15150	COG2937	Belongs to the GPAT DAPAT family
JC965_15155	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JC965_15160	COG3161	chorismate lyase activity
JC965_15165	COG1580	Controls the rotational direction of flagella during chemotaxis
JC965_15180	COG1609	Transcriptional regulator
JC965_15205	COG1215	transferase activity, transferring glycosyl groups
JC965_15210	COG3307	-O-antigen
JC965_15225	COG1484	DNA-dependent DNA replication
JC965_15265	COG0204	Acyl-transferase
JC965_15270	COG0204	Acyl-transferase
JC965_15285	COG1335	isochorismatase
JC965_15295	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
JC965_15300	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
JC965_15305	COG3639	organic phosphonate transmembrane transporter activity
JC965_15310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JC965_15315	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JC965_15325	COG3084	Protein conserved in bacteria
JC965_15330	COG2203	Gaf domain
JC965_15330	COG5001	Diguanylate cyclase
JC965_15330	COG3706	GGDEF domain
JC965_15330	COG4251	negative regulation of phosphorylation
JC965_15345	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JC965_15350	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JC965_15355	COG1561	YicC-like family, N-terminal region
JC965_15370	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JC965_15375	COG0583	DNA-binding transcription factor activity
JC965_15385	COG4774	siderophore transport
JC965_15395	COG3706	GGDEF domain
JC965_15400	COG2200	EAL domain
JC965_15405	COG1917	Cupin 2, conserved barrel domain protein
JC965_15405	COG4977	sequence-specific DNA binding
JC965_15410	COG0583	DNA-binding transcription factor activity
JC965_15415	COG2910	NAD(P)H-binding
JC965_15425	COG0626	cystathionine gamma-synthase activity
JC965_15430	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JC965_15485	COG0675	Transposase, IS605 OrfB family
JC965_15490	COG1609	Transcriptional regulator
JC965_15500	COG4172	Belongs to the ABC transporter superfamily
JC965_15510	COG4171	peptide transport system, permease
JC965_15525	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JC965_15530	COG1842	Phage shock protein A
JC965_15545	COG3106	COG3106 Predicted ATPase
JC965_15550	COG3768	UPF0283 membrane protein
JC965_15560	COG2154	pterin-4-alpha-carbinolamine dehydratase
JC965_15575	COG2199	diguanylate cyclase activity
JC965_15580	COG2885	chlorophyll binding
JC965_15620	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JC965_15640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JC965_15645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JC965_15650	COG1309	transcriptional regulator
JC965_15665	COG1946	Acyl-CoA thioesterase
JC965_15680	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JC965_15690	COG0009	L-threonylcarbamoyladenylate synthase
JC965_15695	COG0613	PHP domain protein
JC965_15700	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JC965_15705	COG0512	Glutamine amidotransferase of anthranilate synthase
JC965_15705	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JC965_15710	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JC965_15715	COG0135	phosphoribosylanthranilate isomerase activity
JC965_15715	COG0134	indole-3-glycerol-phosphate synthase activity
JC965_15720	COG0133	tryptophan synthase activity
JC965_15725	COG0159	tryptophan synthase activity
JC965_15735	COG0675	Transposase, IS605 OrfB family
JC965_15760	COG1024	Enoyl-CoA hydratase
JC965_15765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JC965_15770	COG1960	acyl-CoA dehydrogenase activity
JC965_15780	COG1960	acyl-CoA dehydrogenase activity
JC965_15785	COG1024	Enoyl-CoA hydratase
JC965_15790	COG1024	Enoyl-CoA hydratase
JC965_15800	COG1028	Short-chain dehydrogenase reductase Sdr
JC965_15810	COG0730	response to heat
JC965_15830	COG3267	Type II secretory pathway component ExeA
JC965_15830	COG3409	Peptidoglycan-binding domain 1 protein
JC965_15850	COG2948	multi-organism process
JC965_15860	COG0583	DNA-binding transcription factor activity
JC965_15865	COG1846	Transcriptional regulator
JC965_15895	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JC965_15905	COG0583	DNA-binding transcription factor activity
JC965_15915	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JC965_15920	COG0625	glutathione transferase activity
JC965_15985	COG2198	Histidine kinase
JC965_15985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JC965_15985	COG2205	protein histidine kinase activity
JC965_15985	COG0784	Response regulator, receiver
JC965_16010	COG0784	Response regulator, receiver
JC965_16010	COG2205	protein histidine kinase activity
JC965_16020	COG1388	LysM domain
JC965_16020	COG1376	ErfK ybiS ycfS ynhG family protein
JC965_16035	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
JC965_16040	COG0791	NLP P60 protein
JC965_16050	COG3118	belongs to the thioredoxin family
JC965_16060	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JC965_16065	COG0788	formyltetrahydrofolate deformylase activity
JC965_16090	COG0739	heme binding
JC965_16090	COG0741	lytic transglycosylase activity
JC965_16090	COG1196	nuclear chromosome segregation
JC965_16095	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JC965_16100	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JC965_16110	COG0673	inositol 2-dehydrogenase activity
JC965_16140	COG0751	glycine-tRNA ligase activity
JC965_16145	COG0752	glycyl-tRNA synthetase alpha subunit
JC965_16150	COG2818	Glycosylase
JC965_16155	COG1335	isochorismatase
JC965_16165	COG2885	chlorophyll binding
JC965_16185	COG0251	oxidation-reduction process
JC965_16190	COG0425	Belongs to the sulfur carrier protein TusA family
JC965_16215	COG0183	Belongs to the thiolase family
JC965_16220	COG1024	Enoyl-CoA hydratase
JC965_16220	COG1250	3-hydroxyacyl-CoA dehydrogenase
JC965_16225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JC965_16230	COG0006	proline dipeptidase activity
JC965_16235	COG1739	Uncharacterized protein family UPF0029
JC965_16240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JC965_16245	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
JC965_16255	COG3264	Mechanosensitive ion channel
JC965_16255	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
JC965_16260	COG1966	Carbon starvation protein
JC965_16265	COG3279	Response regulator of the LytR AlgR family
JC965_16270	COG3275	phosphorelay sensor kinase activity
JC965_16280	COG1012	belongs to the aldehyde dehydrogenase family
JC965_16280	COG1454	alcohol dehydrogenase
JC965_16285	COG2095	MarC family integral membrane protein
JC965_16295	COG0601	transmembrane transport
JC965_16300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JC965_16305	COG0444	Belongs to the ABC transporter superfamily
JC965_16315	COG0861	Integral membrane protein TerC family
JC965_16320	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JC965_16330	COG1301	dicarboxylic acid transport
JC965_16350	COG0477	Major facilitator Superfamily
JC965_16355	COG0583	DNA-binding transcription factor activity
JC965_16360	COG3227	Zinc metalloprotease (Elastase)
JC965_16365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JC965_16370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JC965_16380	COG2731	YhcH YjgK YiaL family protein
JC965_16390	COG0668	transmembrane transport
JC965_16400	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JC965_16410	COG0789	Transcriptional regulator
JC965_16450	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JC965_16465	COG0537	adenosine 5'-monophosphoramidase activity
JC965_16500	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JC965_16505	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JC965_16520	COG2354	Protein conserved in bacteria
JC965_16525	COG1164	Oligoendopeptidase f
JC965_16530	COG1164	Oligoendopeptidase f
JC965_16535	COG3150	esterase
JC965_16540	COG1252	NADH dehydrogenase
JC965_16555	COG2985	domain, Protein
JC965_16555	COG0569	domain protein
JC965_16560	COG1272	protein, Hemolysin III
JC965_16565	COG0076	glutamate decarboxylase activity
JC965_16570	COG2917	probably involved in intracellular septation
JC965_16575	COG2350	Protein conserved in bacteria
JC965_16585	COG1555	photosystem II stabilization
JC965_16590	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JC965_16595	COG3104	oligopeptide transport
JC965_16600	COG0745	RESPONSE REGULATOR receiver
JC965_16630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JC965_16645	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
JC965_16650	COG1280	lysine exporter protein (LysE YggA)
JC965_16660	COG1720	tRNA m6t6A37 methyltransferase activity
JC965_16675	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JC965_16680	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JC965_16685	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JC965_16695	COG2190	(PTS) system
JC965_16700	COG3038	cytochrome b561
JC965_16710	COG0420	3'-5' exonuclease activity
JC965_16715	COG1247	-acetyltransferase
JC965_16720	COG2974	May be involved in recombination
JC965_16730	COG0405	Gamma-glutamyltransferase
JC965_16735	COG4651	solute:proton antiporter activity
JC965_16735	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JC965_16760	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JC965_16780	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JC965_16785	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JC965_16790	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JC965_16795	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JC965_16820	COG2716	regulation of RNA biosynthetic process
JC965_16825	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JC965_16835	COG2239	Acts as a magnesium transporter
JC965_16860	COG1120	ATPase activity
JC965_16865	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JC965_16870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JC965_16875	COG4771	TonB-dependent receptor
JC965_16915	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JC965_16920	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JC965_16925	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JC965_16930	COG0861	Integral membrane protein TerC family
JC965_16945	COG1022	Amp-dependent synthetase and ligase
JC965_16955	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JC965_16955	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
JC965_16970	COG0084	hydrolase, TatD family'
JC965_16975	COG0470	DNA polymerase III
JC965_16980	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JC965_16985	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JC965_16990	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JC965_16995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JC965_17000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JC965_17005	COG1028	Short-chain dehydrogenase reductase Sdr
JC965_17015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JC965_17020	COG0416	fatty acid biosynthetic process
JC965_17025	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JC965_17030	COG1399	metal-binding, possibly nucleic acid-binding protein
JC965_17045	COG0564	pseudouridine synthase activity
JC965_17050	COG1530	ribonuclease E activity
JC965_17095	COG0411	ABC transporter
JC965_17105	COG0829	nickel cation binding
JC965_17110	COG0831	urea catabolic process
JC965_17115	COG0832	Belongs to the urease beta subunit family
JC965_17120	COG0804	urea catabolic process
JC965_17125	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
JC965_17135	COG0830	nickel cation binding
JC965_17140	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
JC965_17185	COG1484	DNA-dependent DNA replication
JC965_17195	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JC965_17200	COG1393	Belongs to the ArsC family
JC965_17205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JC965_17210	COG1876	peptidase activity
JC965_17220	COG3263	regulation of cellular component size
JC965_17230	COG1280	lysine exporter protein (LysE YggA)
JC965_17255	COG1957	nucleoside hydrolase
JC965_17270	COG1454	alcohol dehydrogenase
JC965_17275	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JC965_17280	COG0702	epimerase
JC965_17285	COG2914	Belongs to the UPF0125 (RnfH) family
JC965_17290	COG2867	negative regulation of translational initiation
JC965_17295	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JC965_17315	COG3039	Transposase
JC965_17335	COG0577	efflux transmembrane transporter activity
JC965_17340	COG1136	(ABC) transporter
JC965_17360	COG2814	Major facilitator Superfamily
JC965_17385	COG0672	)-iron permease
JC965_17420	COG0306	phosphate transporter
JC965_17425	COG0717	Belongs to the dCTP deaminase family
JC965_17430	COG0572	uridine kinase
JC965_17435	COG0489	protein tyrosine kinase activity
JC965_17440	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JC965_17440	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JC965_17450	COG1254	Belongs to the acylphosphatase family
JC965_17455	COG0840	transmembrane signaling receptor activity
JC965_17460	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JC965_17475	COG0709	Synthesizes selenophosphate from selenide and ATP
JC965_17480	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
JC965_17485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JC965_17490	COG3437	response regulator, receiver
JC965_17515	COG0254	rRNA binding
JC965_17520	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JC965_17525	COG1309	transcriptional regulator
JC965_17545	COG0129	dihydroxy-acid dehydratase activity
JC965_17555	COG3978	acetolactate synthase activity
JC965_17625	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JC965_17630	COG0083	homoserine kinase activity
JC965_17640	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
JC965_17645	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
JC965_17660	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JC965_17670	COG0745	RESPONSE REGULATOR receiver
JC965_17685	COG4988	ABC transporter
JC965_17690	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JC965_17715	COG2801	Transposase and inactivated derivatives
JC965_17755	COG1349	DNA-binding transcription factor activity
JC965_17765	COG1028	Short-chain dehydrogenase reductase Sdr
JC965_17770	COG3731	PTS system glucitol sorbitol-specific IIA component
JC965_17780	COG3730	PTS system glucitol sorbitol-specific
JC965_17820	COG1484	DNA-dependent DNA replication
JC965_17860	COG1396	sequence-specific DNA binding
JC965_17865	COG3135	benzoate transporter
JC965_17895	COG3047	cAMP biosynthetic process
JC965_17900	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JC965_17905	COG2197	response regulator
JC965_17945	COG1737	Transcriptional regulator
JC965_17950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JC965_17950	COG2190	(PTS) system
JC965_17950	COG1263	PTS System
JC965_17955	COG2723	6-phospho-beta-galactosidase activity
JC965_17970	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
JC965_17980	COG3550	peptidyl-serine autophosphorylation
JC965_18030	COG0433	COG0433 Predicted ATPase
JC965_18035	COG1448	Aminotransferase
JC965_18050	COG1199	ATP-dependent helicase activity
JC965_18060	COG0123	including yeast histone deacetylase and acetoin utilization protein
JC965_18065	COG0477	Major facilitator Superfamily
JC965_18070	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JC965_18075	COG1785	Belongs to the alkaline phosphatase family
JC965_18095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JC965_18125	COG2132	Multicopper oxidase
JC965_18155	COG1278	Cold shock
JC965_18190	COG0347	Belongs to the P(II) protein family
JC965_18195	COG0004	ammonium transporteR
JC965_18210	COG0737	Belongs to the 5'-nucleotidase family
JC965_18225	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JC965_18230	COG0506	proline dehydrogenase activity
JC965_18230	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
JC965_18230	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
JC965_18240	COG0114	fumarate hydratase activity
JC965_18250	COG1966	Carbon starvation protein
JC965_18255	COG3279	Response regulator of the LytR AlgR family
JC965_18260	COG3275	phosphorelay sensor kinase activity
JC965_18275	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JC965_18290	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JC965_18295	COG1115	amino acid carrier protein
JC965_18310	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JC965_18320	COG0189	ligase activity
JC965_18325	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JC965_18335	COG3091	SprT-like family
JC965_18345	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JC965_18370	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JC965_18385	COG0583	DNA-binding transcription factor activity
JC965_18395	COG2723	6-phospho-beta-galactosidase activity
JC965_18400	COG0583	DNA-binding transcription factor activity
JC965_18410	COG0243	molybdopterin cofactor binding
JC965_18415	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JC965_18430	COG0583	DNA-binding transcription factor activity
JC965_18485	COG1566	PFAM secretion protein HlyD family protein
JC965_18490	COG1061	Type III restriction enzyme res subunit
JC965_18495	COG2027	D-alanyl-D-alanine carboxypeptidase
JC965_18500	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JC965_18510	COG0436	Aminotransferase
JC965_18515	COG1288	antiporter activity
JC965_18520	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JC965_18585	COG1113	amino acid transport
JC965_18595	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JC965_18600	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JC965_18600	COG0574	Belongs to the PEP-utilizing enzyme family
JC965_18605	COG1119	ATPase activity
JC965_18655	COG1705	Flagellar rod assembly protein muramidase FlgJ
JC965_18655	COG3951	Flagellar rod assembly protein muramidase FlgJ
JC965_18660	COG1706	bacterial-type flagellum-dependent cell motility
JC965_18665	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
JC965_18680	COG1749	Flagellar hook protein flgE
JC965_18695	COG1815	bacterial-type flagellum-dependent cell motility
JC965_18700	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JC965_18705	COG0784	Response regulator, receiver
JC965_18705	COG0835	chemotaxis
JC965_18710	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
JC965_18725	COG0622	Phosphoesterase
JC965_18730	COG0675	Transposase, IS605 OrfB family
JC965_18765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JC965_18770	COG1396	sequence-specific DNA binding
JC965_18770	COG1917	Cupin 2, conserved barrel domain protein
JC965_18775	COG1012	belongs to the aldehyde dehydrogenase family
JC965_18790	COG0531	amino acid
JC965_18795	COG0531	amino acid
JC965_18805	COG1283	sodium-dependent phosphate transmembrane transporter activity
JC965_18815	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
JC965_18820	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
JC965_18825	COG1979	alcohol dehydrogenase
JC965_18830	COG2207	Transcriptional regulator
JC965_18835	COG3040	lipid binding
JC965_18870	COG0540	Belongs to the ATCase OTCase family
JC965_18875	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
JC965_18880	COG1438	arginine binding
JC965_18905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JC965_18915	COG0156	8-amino-7-oxononanoate synthase activity
JC965_18920	COG1063	alcohol dehydrogenase
JC965_18940	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JC965_18945	COG2166	iron-sulfur cluster assembly
JC965_18950	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JC965_18975	COG1960	acyl-CoA dehydrogenase activity
JC965_18980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JC965_18990	COG0469	pyruvate kinase activity
JC965_18995	COG1737	Transcriptional regulator
JC965_19000	COG0837	glucose binding
JC965_19020	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JC965_19025	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JC965_19030	COG0531	amino acid
JC965_19030	COG1674	ftsk spoiiie
JC965_19040	COG0686	Belongs to the AlaDH PNT family
JC965_19045	COG0492	ferredoxin-NADP+ reductase activity
JC965_19050	COG3706	GGDEF domain
JC965_19055	COG3134	Outer membrane lipoprotein
JC965_19060	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
JC965_19065	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
JC965_19070	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JC965_19075	COG0542	response to heat
JC965_19080	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JC965_19085	COG1278	Cold shock
JC965_19090	COG3335	DDE superfamily endonuclease
JC965_19105	COG3148	PFAM DTW domain containing protein
JC965_19110	COG1181	Belongs to the D-alanine--D-alanine ligase family
JC965_19120	COG0386	Belongs to the glutathione peroxidase family
JC965_19125	COG0513	Belongs to the DEAD box helicase family
JC965_19160	COG2329	Antibiotic biosynthesis monooxygenase
JC965_19165	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
JC965_19190	COG0675	Transposase, IS605 OrfB family
JC965_19215	COG0765	amino acid transport
JC965_19235	COG0596	Alpha beta hydrolase
JC965_19245	COG3842	ATPase activity
JC965_19250	COG3833	ABC-type maltose transport systems, permease component
JC965_19255	COG1175	transmembrane transport
JC965_19265	COG3081	Nucleoid-associated protein
JC965_19270	COG3082	Protein of unknown function (DUF1414)
JC965_19275	COG3083	sulfuric ester hydrolase activity
JC965_19280	COG4771	TonB-dependent receptor
JC965_19290	COG0675	Transposase, IS605 OrfB family
JC965_19315	COG0765	amino acid transport
JC965_19330	COG3385	transposase activity
JC965_19335	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JC965_19340	COG0085	RNA polymerase activity
JC965_19345	COG0222	ribosome binding
JC965_19350	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JC965_19355	COG0081	regulation of translation
JC965_19360	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JC965_19365	COG0250	Participates in transcription elongation, termination and antitermination
JC965_19385	COG1187	pseudouridine synthase activity
JC965_19395	COG0482	sulfurtransferase activity
JC965_19400	COG2915	High frequency lysogenization protein hflD homolog
JC965_19405	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JC965_19410	COG2850	peptidyl-arginine hydroxylation
JC965_19420	COG3264	Mechanosensitive ion channel
JC965_19420	COG1196	nuclear chromosome segregation
JC965_19470	COG0446	pyridine nucleotide-disulphide oxidoreductase
JC965_19480	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JC965_19505	COG1271	oxidase subunit
JC965_19510	COG1294	oxidase, subunit
JC965_19520	COG2814	Major facilitator Superfamily
JC965_19525	COG0656	L-ascorbic acid biosynthetic process
JC965_19545	COG0583	DNA-binding transcription factor activity
JC965_19550	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JC965_19555	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JC965_19570	COG2333	competence protein COMEC
JC965_19570	COG0658	competence protein
JC965_19575	COG1132	(ABC) transporter
JC965_19580	COG1663	tetraacyldisaccharide 4'-kinase activity
JC965_19585	COG2835	tetraacyldisaccharide 4'-kinase activity
JC965_19590	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
JC965_19595	COG2197	response regulator
JC965_19600	COG0322	excinuclease ABC activity
JC965_19645	COG0583	DNA-binding transcription factor activity
JC965_19660	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JC965_19665	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JC965_19670	COG2223	nitrite transmembrane transporter activity
JC965_19675	COG3279	Response regulator of the LytR AlgR family
JC965_19680	COG3275	phosphorelay sensor kinase activity
JC965_19700	COG0720	synthase
JC965_19725	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JC965_19730	COG0602	queuosine metabolic process
JC965_19740	COG2003	Belongs to the UPF0758 family
JC965_19805	COG1917	Cupin 2, conserved barrel domain protein
JC965_19805	COG2207	Transcriptional regulator
JC965_19815	COG0513	Belongs to the DEAD box helicase family
JC965_19820	COG2203	Gaf domain
JC965_19820	COG2199	diguanylate cyclase activity
JC965_19855	COG4681	YaeQ
JC965_19875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JC965_19890	COG3134	Outer membrane lipoprotein
JC965_19960	COG0531	amino acid
JC965_19975	COG1253	flavin adenine dinucleotide binding
JC965_19980	COG0704	Plays a role in the regulation of phosphate uptake
JC965_19985	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JC965_19990	COG0581	inorganic phosphate transmembrane transporter activity
JC965_19995	COG0573	inorganic phosphate transmembrane transporter activity
JC965_20000	COG0590	tRNA wobble adenosine to inosine editing
JC965_20020	COG2271	Major facilitator Superfamily
JC965_20025	COG1349	DNA-binding transcription factor activity
JC965_20035	COG0584	glycerophosphoryl diester phosphodiesterase
JC965_20040	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JC965_20045	COG1605	Chorismate mutase
JC965_20045	COG0287	Prephenate dehydrogenase
JC965_20055	COG3085	chromosome segregation
JC965_20060	COG4574	serine-type endopeptidase inhibitor activity
JC965_20105	COG0438	transferase activity, transferring glycosyl groups
JC965_20105	COG1216	Glycosyl transferase, family 2
JC965_20110	COG0438	transferase activity, transferring glycosyl groups
JC965_20110	COG1216	Glycosyl transferase, family 2
JC965_20150	COG5507	3-demethylubiquinone-9 3-methyltransferase
JC965_20155	COG2814	Major facilitator Superfamily
JC965_20160	COG0109	protoheme IX farnesyltransferase activity
JC965_20165	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JC965_20170	COG1845	cytochrome c oxidase, subunit III
JC965_20175	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JC965_20180	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JC965_20190	COG0583	DNA-binding transcription factor activity
JC965_20215	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JC965_20225	COG1473	amidohydrolase
JC965_20230	COG3069	C4-dicarboxylate transmembrane transporter activity
JC965_20245	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JC965_20320	COG2983	Belongs to the UPF0260 family
JC965_20325	COG1882	Formate acetyltransferase
JC965_20330	COG2116	formate transmembrane transporter activity
JC965_20335	COG1944	ATP diphosphatase activity
JC965_20350	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JC965_20370	COG1139	Iron-sulfur cluster binding protein
JC965_20375	COG0247	lactate metabolic process
JC965_20380	COG1620	l-lactate permease
JC965_20385	COG0583	DNA-binding transcription factor activity
JC965_20410	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JC965_20425	COG3220	belongs to the UPF0276 family
JC965_20455	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JC965_20460	COG1289	transmembrane transporter activity
JC965_20475	COG1584	GPR1 FUN34 yaaH family protein
JC965_20480	COG3228	Belongs to the MtfA family
JC965_20490	COG1115	amino acid carrier protein
JC965_20495	COG1024	Enoyl-CoA hydratase
JC965_20510	COG3162	membrane
JC965_20515	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JC965_20520	COG2195	Cleaves the N-terminal amino acid of tripeptides
JC965_20535	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JC965_20550	COG0583	DNA-binding transcription factor activity
JC965_20560	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JC965_20580	COG0438	transferase activity, transferring glycosyl groups
JC965_20580	COG1216	Glycosyl transferase, family 2
JC965_20600	COG1091	dTDP-4-dehydrorhamnose reductase activity
JC965_20635	COG1846	Transcriptional regulator
JC965_20650	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
JC965_20665	COG0745	RESPONSE REGULATOR receiver
JC965_20675	COG0708	Exodeoxyribonuclease III
JC965_20710	COG2205	protein histidine kinase activity
JC965_20715	COG0745	RESPONSE REGULATOR receiver
JC965_20720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JC965_20740	COG0442	prolyl-tRNA aminoacylation
JC965_20745	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JC965_20750	COG4221	oxidoreductase activity
JC965_20765	COG1024	Enoyl-CoA hydratase
JC965_20780	COG4166	transmembrane transport
JC965_20805	COG2089	acid synthase
JC965_20810	COG0483	inositol monophosphate 1-phosphatase activity
JC965_20815	COG1083	cytidylyl-transferase
JC965_20865	COG0582	viral genome integration into host DNA
JC965_20915	COG1166	arginine decarboxylase activity
JC965_20940	COG0714	Associated with various cellular activities
JC965_20945	COG0183	Belongs to the thiolase family
JC965_20950	COG1250	3-hydroxyacyl-CoA dehydrogenase
JC965_20950	COG1024	Enoyl-CoA hydratase
JC965_20960	COG0584	glycerophosphoryl diester phosphodiesterase
JC965_20965	COG1511	domain protein
JC965_20965	COG3264	Mechanosensitive ion channel
JC965_20975	COG0739	heme binding
JC965_21000	COG0393	Putative heavy-metal-binding
JC965_21005	COG1368	sulfuric ester hydrolase activity
JC965_21015	COG0527	aspartate kinase activity
JC965_21020	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JC965_21020	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JC965_21065	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JC965_21080	COG0675	Transposase, IS605 OrfB family
JC965_21090	COG1609	Transcriptional regulator
JC965_21095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JC965_21100	COG1879	ABC-type sugar transport system periplasmic component
JC965_21105	COG1172	Belongs to the binding-protein-dependent transport system permease family
JC965_21110	COG1129	ABC transporter
JC965_21115	COG1869	D-ribose catabolic process
JC965_21120	COG0625	glutathione transferase activity
JC965_21140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JC965_21145	COG0800	Aldolase
JC965_21160	COG3153	acetyltransferase
JC965_21195	COG0675	Transposase, IS605 OrfB family
JC965_21200	COG2996	Protein conserved in bacteria
JC965_21215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JC965_21220	COG3099	Belongs to the UPF0263 family
JC965_21225	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
JC965_21230	COG2894	cell division
JC965_21235	COG0850	regulation of cytokinetic process
JC965_21240	COG3100	YcgL domain-containing protein
JC965_21245	COG2951	lytic endotransglycosylase activity
JC965_21265	COG1595	DNA-templated transcription, initiation
JC965_21275	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
JC965_21280	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JC965_21300	COG3220	belongs to the UPF0276 family
JC965_21345	COG3039	Transposase
JC965_21440	COG0281	malic enzyme
JC965_21445	COG0746	molybdenum cofactor guanylyltransferase activity
JC965_21455	COG3335	DDE superfamily endonuclease
JC965_21465	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JC965_21470	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JC965_21475	COG0697	spore germination
JC965_21480	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JC965_21565	COG0675	Transposase, IS605 OrfB family
JC965_21570	COG0675	Transposase, IS605 OrfB family
JC965_21595	COG0259	pyridoxamine-phosphate oxidase activity
JC965_21610	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JC965_21610	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JC965_21615	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JC965_21635	COG0604	alcohol dehydrogenase
JC965_21640	COG1309	transcriptional regulator
JC965_21645	COG2261	transglycosylase associated protein
JC965_21650	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JC965_21660	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JC965_21680	COG0417	DNA replication proofreading
JC965_21710	COG0534	Mate efflux family protein
JC965_21720	COG0307	riboflavin synthase, alpha
JC965_21735	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JC965_21740	COG1286	toxin biosynthetic process
JC965_21745	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JC965_21765	COG2964	Protein conserved in bacteria
JC965_21770	COG0251	oxidation-reduction process
JC965_21775	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
JC965_21785	COG2168	tRNA wobble position uridine thiolation
JC965_21790	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JC965_21795	COG0049	tRNA binding
JC965_21800	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JC965_21810	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
JC965_21820	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JC965_21820	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JC965_21840	COG0583	DNA-binding transcription factor activity
JC965_21850	COG1560	Kdo2-lipid A biosynthetic process
JC965_21855	COG1560	Kdo2-lipid A biosynthetic process
JC965_21875	COG1396	sequence-specific DNA binding
JC965_21880	COG3550	peptidyl-serine autophosphorylation
JC965_21925	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
JC965_21945	COG5642	Protein of unknown function (DUF2384)
JC965_21980	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JC965_21985	COG0739	heme binding
JC965_21990	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JC965_22015	COG4160	amino acid transport
JC965_22025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JC965_22035	COG2431	L-lysine efflux transmembrane transporter activity
JC965_22050	COG0784	Response regulator, receiver
JC965_22050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JC965_22050	COG2198	Histidine kinase
JC965_22050	COG2205	protein histidine kinase activity
JC965_22055	COG0745	RESPONSE REGULATOR receiver
JC965_22090	COG1538	Outer membrane efflux protein
JC965_22120	COG1484	DNA-dependent DNA replication
JC965_22130	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JC965_22135	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JC965_22140	COG2200	EAL domain
JC965_22160	COG0675	Transposase, IS605 OrfB family
JC965_22170	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JC965_22185	COG4166	transmembrane transport
JC965_22225	COG0659	secondary active sulfate transmembrane transporter activity
JC965_22275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JC965_22280	COG0765	amino acid transport
JC965_22285	COG1126	abc transporter atp-binding protein
JC965_22315	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
JC965_22335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JC965_22365	COG1484	DNA-dependent DNA replication
JC965_22390	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JC965_22395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JC965_22405	COG0745	RESPONSE REGULATOR receiver
JC965_22410	COG5002	protein histidine kinase activity
JC965_22435	COG3008	intermembrane lipid transfer
JC965_22440	COG2995	paraquat-inducible protein a
JC965_22455	COG0675	Transposase, IS605 OrfB family
JC965_22465	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JC965_22470	COG1187	pseudouridine synthase activity
JC965_22485	COG3384	dioxygenase
JC965_22490	COG2205	protein histidine kinase activity
JC965_22490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JC965_22495	COG0675	Transposase, IS605 OrfB family
JC965_22510	COG1393	Belongs to the ArsC family
JC965_22520	COG4783	chaperone-mediated protein folding
JC965_22560	COG1484	DNA-dependent DNA replication
JC965_22590	COG1380	Effector of murein hydrolase LrgA
JC965_22595	COG1346	cytolysis
JC965_22600	COG0295	cytidine deaminase activity
JC965_22650	COG4372	Transposase
JC965_22655	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JC965_22745	COG3039	Transposase
JC965_22770	COG0840	transmembrane signaling receptor activity
JC965_22805	COG2203	Gaf domain
JC965_22805	COG2199	diguanylate cyclase activity
JC965_22910	COG0697	spore germination
JC965_22915	COG4166	transmembrane transport
JC965_22935	COG0583	DNA-binding transcription factor activity
JC965_22995	COG2862	Uncharacterized protein family, UPF0114
JC965_23040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JC965_23065	COG2501	S4 domain
JC965_23085	COG2308	Evidence 4 Homologs of previously reported genes of
JC965_23110	COG1091	dTDP-4-dehydrorhamnose reductase activity
JC965_23140	COG3039	Transposase
JC965_23175	COG0697	spore germination
JC965_23210	COG0675	Transposase, IS605 OrfB family
JC965_23230	COG3039	Transposase
JC965_23270	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JC965_23295	COG0675	Transposase, IS605 OrfB family
JC965_23305	COG0675	Transposase, IS605 OrfB family
JC965_23310	COG1484	DNA-dependent DNA replication
JC965_23315	COG4584	PFAM Integrase catalytic
JC965_23320	COG1484	DNA-dependent DNA replication
JC965_23325	COG4584	PFAM Integrase catalytic
JC965_23335	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JC965_23340	COG0675	Transposase, IS605 OrfB family
JC965_23445	COG3039	Transposase
JC965_23495	COG2203	Gaf domain
JC965_23495	COG2200	EAL domain
JC965_23495	COG2199	diguanylate cyclase activity
JC965_23540	COG0675	Transposase, IS605 OrfB family
JC965_23545	COG0840	transmembrane signaling receptor activity
JC965_23570	COG0675	Transposase, IS605 OrfB family
JC965_23620	COG0675	Transposase, IS605 OrfB family
JC965_23630	COG0675	Transposase, IS605 OrfB family
JC965_23640	COG3437	response regulator, receiver
JC965_23640	COG0784	Response regulator, receiver
JC965_23900	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JC965_23935	COG4584	PFAM Integrase catalytic
JC965_24020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JC965_24020	COG1263	PTS System
JC965_24165	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
JC965_24280	COG3039	Transposase
JC965_24305	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
JC965_24330	COG2801	Transposase and inactivated derivatives
JC965_24340	COG3039	Transposase
JC965_24360	COG1484	DNA-dependent DNA replication
JC965_24450	COG1278	Cold shock
JC965_24590	COG0456	acetyltransferase
JC965_24840	COG3039	Transposase
JC965_24870	COG1484	DNA-dependent DNA replication
JC965_24945	COG1484	DNA-dependent DNA replication
JC965_24990	COG1484	DNA-dependent DNA replication
JC965_25055	COG0675	Transposase, IS605 OrfB family
JC965_25155	COG1484	DNA-dependent DNA replication
JC965_25195	COG2337	Toxic component of a toxin-antitoxin (TA) module
JC965_25220	COG2337	Toxic component of a toxin-antitoxin (TA) module
JC965_25430	COG1484	DNA-dependent DNA replication
JC965_25475	COG0675	Transposase, IS605 OrfB family
JC965_25505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JC965_25505	COG1263	PTS System
JC965_25525	COG0675	Transposase, IS605 OrfB family
JC965_25590	COG0675	Transposase, IS605 OrfB family
JC965_25620	COG0675	Transposase, IS605 OrfB family
JC965_25730	COG0675	Transposase, IS605 OrfB family
JC965_25735	COG0675	Transposase, IS605 OrfB family
JC965_25840	COG3039	Transposase
JC965_25865	COG0675	Transposase, IS605 OrfB family