locus-tag	class	description
NRL03_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NRL03_00010	COG0592	DNA-directed DNA polymerase activity
NRL03_00020	COG0187	DNA topoisomerase II activity
NRL03_00025	COG2207	Transcriptional regulator
NRL03_00030	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NRL03_00035	COG0071	Belongs to the small heat shock protein (HSP20) family
NRL03_00040	COG0071	Belongs to the small heat shock protein (HSP20) family
NRL03_00045	COG3977	Valine--pyruvate aminotransferase
NRL03_00065	COG2814	Major facilitator Superfamily
NRL03_00070	COG0745	RESPONSE REGULATOR receiver
NRL03_00075	COG2205	protein histidine kinase activity
NRL03_00095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NRL03_00100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRL03_00100	COG4191	Histidine kinase
NRL03_00105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRL03_00110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRL03_00115	COG1309	transcriptional regulator
NRL03_00145	COG0561	phosphatase activity
NRL03_00150	COG2267	carboxylic ester hydrolase activity
NRL03_00155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NRL03_00160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NRL03_00165	COG1758	RNA polymerase activity
NRL03_00175	COG0859	PFAM glycosyl transferase family 9
NRL03_00180	COG3642	lipopolysaccharide core region biosynthetic process
NRL03_00220	COG0589	response to stress
NRL03_00225	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NRL03_00230	COG3706	GGDEF domain
NRL03_00235	COG1528	Iron-storage protein
NRL03_00240	COG2081	HI0933 family
NRL03_00245	COG2223	nitrite transmembrane transporter activity
NRL03_00250	COG1280	lysine exporter protein (LysE YggA)
NRL03_00270	COG2205	protein histidine kinase activity
NRL03_00270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRL03_00280	COG3275	phosphorelay sensor kinase activity
NRL03_00285	COG3279	Response regulator of the LytR AlgR family
NRL03_00290	COG2223	nitrite transmembrane transporter activity
NRL03_00295	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NRL03_00300	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NRL03_00315	COG0583	DNA-binding transcription factor activity
NRL03_00360	COG0045	succinate-CoA ligase (ADP-forming) activity
NRL03_00360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRL03_00360	COG1042	CoA-binding domain protein
NRL03_00370	COG0583	DNA-binding transcription factor activity
NRL03_00375	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NRL03_00380	COG0166	Belongs to the GPI family
NRL03_00390	COG0668	transmembrane transport
NRL03_00405	COG1309	transcriptional regulator
NRL03_00410	COG0756	dUTP diphosphatase activity
NRL03_00415	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NRL03_00420	COG2003	Belongs to the UPF0758 family
NRL03_00425	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NRL03_00430	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NRL03_00440	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NRL03_00445	COG2990	Protein conserved in bacteria
NRL03_00450	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NRL03_00455	COG0859	PFAM glycosyl transferase family 9
NRL03_00460	COG0463	Glycosyl transferase, family 2
NRL03_00465	COG0859	PFAM glycosyl transferase family 9
NRL03_00470	COG1519	Transferase
NRL03_00485	COG1561	YicC-like family, N-terminal region
NRL03_00490	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NRL03_00495	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NRL03_00510	COG2203	Gaf domain
NRL03_00510	COG3706	GGDEF domain
NRL03_00510	COG4251	negative regulation of phosphorylation
NRL03_00510	COG5001	Diguanylate cyclase
NRL03_00515	COG3084	Protein conserved in bacteria
NRL03_00525	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NRL03_00530	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NRL03_00535	COG3639	organic phosphonate transmembrane transporter activity
NRL03_00540	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NRL03_00545	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
NRL03_00555	COG1335	isochorismatase
NRL03_00565	COG1683	Conserved Protein
NRL03_00570	COG0204	Acyl-transferase
NRL03_00575	COG0204	Acyl-transferase
NRL03_00580	COG0606	chelatase, subunit chli
NRL03_00590	COG3978	acetolactate synthase activity
NRL03_00600	COG0129	dihydroxy-acid dehydratase activity
NRL03_00620	COG1309	transcriptional regulator
NRL03_00625	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NRL03_00630	COG0254	rRNA binding
NRL03_00635	COG0702	epimerase
NRL03_00640	COG0281	malic enzyme
NRL03_00650	COG2205	protein histidine kinase activity
NRL03_00655	COG0745	RESPONSE REGULATOR receiver
NRL03_00660	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NRL03_00675	COG0366	Alpha amylase catalytic
NRL03_00690	COG0443	Heat shock 70 kDa protein
NRL03_00695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NRL03_00700	COG3045	CreA protein
NRL03_00720	COG0174	glutamine synthetase
NRL03_00740	COG3842	ATPase activity
NRL03_00745	COG1176	ABC-type spermidine putrescine transport system, permease component I
NRL03_00750	COG1177	transmembrane transport
NRL03_00755	COG2258	MOSC domain
NRL03_00770	COG2050	protein possibly involved in aromatic compounds catabolism
NRL03_00775	COG0514	ATP-dependent DNA helicase (RecQ)
NRL03_00785	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NRL03_00795	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NRL03_00800	COG3385	transposase activity
NRL03_00805	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NRL03_00815	COG2239	Acts as a magnesium transporter
NRL03_00820	COG1648	precorrin-2 dehydrogenase activity
NRL03_00820	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NRL03_00825	COG2116	formate transmembrane transporter activity
NRL03_00835	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NRL03_00840	COG0842	Transport permease protein
NRL03_00845	COG0842	Transport permease protein
NRL03_00850	COG1131	(ABC) transporter
NRL03_00855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRL03_00875	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NRL03_00880	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NRL03_00900	COG1595	DNA-templated transcription, initiation
NRL03_00905	COG3806	Anti-sigma factor
NRL03_00910	COG1968	undecaprenyl-diphosphatase activity
NRL03_00915	COG0667	Aldo Keto reductase
NRL03_00920	COG2017	converts alpha-aldose to the beta-anomer
NRL03_00925	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NRL03_00935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NRL03_00940	COG1609	Transcriptional regulator
NRL03_00945	COG3250	beta-galactosidase activity
NRL03_00985	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NRL03_00990	COG1288	antiporter activity
NRL03_00995	COG1438	arginine binding
NRL03_01000	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
NRL03_01005	COG0540	Belongs to the ATCase OTCase family
NRL03_01040	COG3040	lipid binding
NRL03_01045	COG2207	Transcriptional regulator
NRL03_01050	COG1979	alcohol dehydrogenase
NRL03_01055	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NRL03_01060	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NRL03_01065	COG3385	transposase activity
NRL03_01100	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NRL03_01110	COG2204	response regulator
NRL03_01120	COG2205	protein histidine kinase activity
NRL03_01140	COG0517	IMP dehydrogenase activity
NRL03_01140	COG0516	GMP reductase activity
NRL03_01150	COG1522	sequence-specific DNA binding
NRL03_01155	COG2502	aspartate--ammonia ligase
NRL03_01160	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NRL03_01165	COG0542	response to heat
NRL03_01175	COG0564	pseudouridine synthase activity
NRL03_01180	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NRL03_01185	COG3681	Belongs to the UPF0597 family
NRL03_01190	COG2964	Protein conserved in bacteria
NRL03_01200	COG3385	transposase activity
NRL03_01210	COG0243	molybdopterin cofactor binding
NRL03_01215	COG3005	denitrification pathway
NRL03_01220	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NRL03_01245	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NRL03_01250	COG0569	domain protein
NRL03_01255	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NRL03_01280	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NRL03_01295	COG0250	Participates in transcription elongation, termination and antitermination
NRL03_01300	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NRL03_01305	COG0081	regulation of translation
NRL03_01310	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NRL03_01315	COG0222	ribosome binding
NRL03_01320	COG0085	RNA polymerase activity
NRL03_01325	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NRL03_01330	COG2964	Protein conserved in bacteria
NRL03_01335	COG0251	oxidation-reduction process
NRL03_01340	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NRL03_01350	COG2168	tRNA wobble position uridine thiolation
NRL03_01355	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NRL03_01360	COG0049	tRNA binding
NRL03_01365	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NRL03_01370	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NRL03_01375	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NRL03_01410	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NRL03_01420	COG2252	PERMEase
NRL03_01425	COG2376	Dihydroxyacetone kinase
NRL03_01430	COG1461	Dihydroxyacetone kinase
NRL03_01445	COG0583	DNA-binding transcription factor activity
NRL03_01450	COG2957	Belongs to the agmatine deiminase family
NRL03_01465	COG2957	Belongs to the agmatine deiminase family
NRL03_01475	COG0628	permease
NRL03_01480	COG0494	nUDIX hydrolase
NRL03_01500	COG0753	catalase activity
NRL03_01505	COG0456	acetyltransferase
NRL03_01535	COG3842	ATPase activity
NRL03_01545	COG1175	transmembrane transport
NRL03_01570	COG0583	DNA-binding transcription factor activity
NRL03_01580	COG1741	Belongs to the pirin family
NRL03_01585	COG2259	Doxx family
NRL03_01590	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NRL03_01595	COG1074	ATP-dependent DNA helicase activity
NRL03_01600	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NRL03_01630	COG0346	lactoylglutathione lyase activity
NRL03_01640	COG0004	ammonium transporteR
NRL03_01645	COG0347	Belongs to the P(II) protein family
NRL03_01650	COG3706	GGDEF domain
NRL03_01680	COG1278	Cold shock
NRL03_01705	COG2197	response regulator
NRL03_01710	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NRL03_01715	COG5433	transposase activity
NRL03_01720	COG3047	cAMP biosynthetic process
NRL03_01750	COG3135	benzoate transporter
NRL03_01755	COG1396	sequence-specific DNA binding
NRL03_01790	COG2926	Belongs to the UPF0265 family
NRL03_01800	COG3028	Belongs to the UPF0307 family
NRL03_01805	COG0312	modulator of DNA gyrase
NRL03_01820	COG3071	HemY protein
NRL03_01825	COG2959	enzyme of heme biosynthesis
NRL03_01835	COG0181	hydroxymethylbilane synthase activity
NRL03_01840	COG3072	Adenylate cyclase
NRL03_01845	COG0400	carboxylic ester hydrolase activity
NRL03_01850	COG1965	Belongs to the frataxin family
NRL03_01860	COG0019	diaminopimelate decarboxylase activity
NRL03_01865	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NRL03_01880	COG1011	Hydrolase
NRL03_01890	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NRL03_01895	COG0561	phosphatase activity
NRL03_01905	COG1988	membrane-bound metal-dependent
NRL03_01910	COG1546	Belongs to the CinA family
NRL03_01910	COG1058	Belongs to the CinA family
NRL03_01920	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NRL03_01930	COG1522	sequence-specific DNA binding
NRL03_01935	COG1368	sulfuric ester hydrolase activity
NRL03_01950	COG1285	pathogenesis
NRL03_01970	COG4221	oxidoreductase activity
NRL03_01985	COG1979	alcohol dehydrogenase
NRL03_01995	COG2873	o-acetylhomoserine
NRL03_02025	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NRL03_02035	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NRL03_02040	COG2949	membrane
NRL03_02045	COG3291	Pkd domain containing protein
NRL03_02050	COG0318	PFAM AMP-dependent synthetase and ligase
NRL03_02060	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NRL03_02065	COG0596	Alpha beta hydrolase
NRL03_02070	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NRL03_02075	COG1169	isochorismate synthase
NRL03_02080	COG1575	Belongs to the MenA family. Type 1 subfamily
NRL03_02100	COG0513	Belongs to the DEAD box helicase family
NRL03_02105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRL03_02120	COG1671	Belongs to the UPF0178 family
NRL03_02140	COG3263	regulation of cellular component size
NRL03_02145	COG3722	fumarate hydratase activity
NRL03_02150	COG0246	Mannitol dehydrogenase
NRL03_02155	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRL03_02155	COG2213	PTS system mannitol-specific
NRL03_02160	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
NRL03_02170	COG3916	Acyl-homoserine-lactone synthase
NRL03_02175	COG2771	luxR family
NRL03_02190	COG1560	Kdo2-lipid A biosynthetic process
NRL03_02195	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NRL03_02195	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NRL03_02200	COG1538	Outer membrane efflux protein
NRL03_02205	COG0494	nUDIX hydrolase
NRL03_02210	COG3151	Protein conserved in bacteria
NRL03_02220	COG3150	esterase
NRL03_02225	COG1051	belongs to the nudix hydrolase family
NRL03_02240	COG1566	PFAM secretion protein HlyD family protein
NRL03_02245	COG1289	transmembrane transporter activity
NRL03_02265	COG5433	transposase activity
NRL03_02305	COG0484	heat shock protein binding
NRL03_02315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NRL03_02335	COG0204	Acyl-transferase
NRL03_02340	COG1842	Phage shock protein A
NRL03_02355	COG2827	Endonuclease containing a URI domain
NRL03_02360	COG2962	Rard protein
NRL03_02365	COG1573	uracil-dna glycosylase
NRL03_02375	COG0583	DNA-binding transcription factor activity
NRL03_02380	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NRL03_02385	COG1121	(ABC) transporter
NRL03_02390	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
NRL03_02410	COG0739	heme binding
NRL03_02415	COG3385	transposase activity
NRL03_02425	COG3068	Protein conserved in bacteria
NRL03_02460	COG1522	sequence-specific DNA binding
NRL03_02465	COG0110	maltose O-acetyltransferase activity
NRL03_02470	COG0366	Alpha amylase catalytic
NRL03_02475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRL03_02475	COG1263	PTS System
NRL03_02495	COG0252	asparaginase activity
NRL03_02510	COG1803	Methylglyoxal synthase
NRL03_02530	COG1444	tRNA N-acetyltransferase activity
NRL03_02535	COG1565	acr, cog1565
NRL03_02535	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NRL03_02545	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
NRL03_02575	COG0109	protoheme IX farnesyltransferase activity
NRL03_02595	COG1177	transmembrane transport
NRL03_02600	COG1176	ABC-type spermidine putrescine transport system, permease component I
NRL03_02605	COG3842	ATPase activity
NRL03_02610	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NRL03_02615	COG0583	DNA-binding transcription factor activity
NRL03_02620	COG1757	Na H antiporter
NRL03_02650	COG0297	glycogen (starch) synthase activity
NRL03_02660	COG2813	Specifically methylates the guanine in position
NRL03_02665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NRL03_02670	COG2203	Gaf domain
NRL03_02670	COG4251	negative regulation of phosphorylation
NRL03_02670	COG3706	GGDEF domain
NRL03_02670	COG5001	Diguanylate cyclase
NRL03_02675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRL03_02685	COG2995	paraquat-inducible protein a
NRL03_02690	COG3008	intermembrane lipid transfer
NRL03_02690	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NRL03_02695	COG3009	Protein conserved in bacteria
NRL03_02705	COG3240	lipase activity
NRL03_02720	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
NRL03_02725	COG1194	a g-specific adenine glycosylase
NRL03_02735	COG3267	Type II secretory pathway component ExeA
NRL03_02735	COG3409	Peptidoglycan-binding domain 1 protein
NRL03_02740	COG0617	tRNA 3'-terminal CCA addition
NRL03_02745	COG0306	phosphate transporter
NRL03_02750	COG1392	Phosphate transport regulator
NRL03_02755	COG3025	triphosphatase activity
NRL03_02760	COG3133	Outer membrane lipoprotein
NRL03_02780	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NRL03_02785	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NRL03_02795	COG3031	protein transport across the cell outer membrane
NRL03_02805	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NRL03_02810	COG1459	type II secretion system
NRL03_02815	COG2165	general secretion pathway protein
NRL03_02825	COG2165	general secretion pathway protein
NRL03_02830	COG4795	General secretion pathway protein
NRL03_02840	COG3156	type II secretion system protein K
NRL03_02850	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
NRL03_02865	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NRL03_02880	COG1011	Hydrolase
NRL03_02885	COG0494	nUDIX hydrolase
NRL03_02890	COG1218	3'(2'),5'-bisphosphate nucleotidase
NRL03_02895	COG0814	amino acid
NRL03_02900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRL03_02915	COG0626	cystathionine gamma-synthase activity
NRL03_02920	COG0527	aspartate kinase activity
NRL03_02920	COG0460	homoserine dehydrogenase
NRL03_02925	COG1346	cytolysis
NRL03_02930	COG1380	Effector of murein hydrolase LrgA
NRL03_02935	COG0583	DNA-binding transcription factor activity
NRL03_02970	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NRL03_02975	COG3447	MASE1 domain protein
NRL03_02975	COG5001	Diguanylate cyclase
NRL03_02975	COG5002	protein histidine kinase activity
NRL03_02980	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NRL03_02990	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NRL03_02995	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NRL03_03005	COG0137	argininosuccinate synthase activity
NRL03_03010	COG0165	Argininosuccinate lyase
NRL03_03020	COG0583	DNA-binding transcription factor activity
NRL03_03030	COG1942	4-Oxalocrotonate Tautomerase
NRL03_03060	COG0110	maltose O-acetyltransferase activity
NRL03_03065	COG3174	membrane
NRL03_03070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRL03_03075	COG1126	abc transporter atp-binding protein
NRL03_03080	COG0765	amino acid transport
NRL03_03085	COG0765	amino acid transport
NRL03_03090	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NRL03_03095	COG1505	serine-type exopeptidase activity
NRL03_03105	COG1028	Short-chain dehydrogenase reductase Sdr
NRL03_03110	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NRL03_03125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NRL03_03130	COG4991	sh3 domain protein
NRL03_03140	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NRL03_03145	COG1940	carbohydrate kinase activity
NRL03_03150	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NRL03_03155	COG0126	phosphoglycerate kinase activity
NRL03_03165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRL03_03195	COG0583	DNA-binding transcription factor activity
NRL03_03200	COG0354	folic acid binding
NRL03_03205	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
NRL03_03215	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NRL03_03220	COG1595	DNA-templated transcription, initiation
NRL03_03225	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
NRL03_03240	COG0481	GTPase activity
NRL03_03245	COG0681	Belongs to the peptidase S26 family
NRL03_03250	COG0571	ribonuclease III activity
NRL03_03260	COG1381	Involved in DNA repair and RecF pathway recombination
NRL03_03265	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NRL03_03270	COG3023	N-Acetylmuramoyl-L-alanine amidase
NRL03_03275	COG4807	Protein conserved in bacteria
NRL03_03285	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NRL03_03290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NRL03_03295	COG3956	TIGRFAM MazG family protein
NRL03_03300	COG0504	CTP synthase activity
NRL03_03305	COG0148	phosphopyruvate hydratase activity
NRL03_03310	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NRL03_03315	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NRL03_03325	COG0585	pseudouridine synthase activity
NRL03_03330	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NRL03_03335	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NRL03_03340	COG1238	metal cluster binding
NRL03_03345	COG4942	peptidase
NRL03_03345	COG1388	LysM domain
NRL03_03355	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NRL03_03360	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NRL03_03365	COG1610	YqeY-like protein
NRL03_03370	COG0358	DNA primase activity
NRL03_03375	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NRL03_03415	COG0138	bifunctional purine biosynthesis protein purh
NRL03_03430	COG3036	rescue of stalled ribosome
NRL03_03435	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NRL03_03440	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NRL03_03450	COG0673	inositol 2-dehydrogenase activity
NRL03_03465	COG1585	Membrane protein implicated in regulation of membrane protease activity
NRL03_03470	COG0330	HflC and HflK could
NRL03_03475	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NRL03_03475	COG1648	precorrin-2 dehydrogenase activity
NRL03_03480	COG0175	sulfate reduction
NRL03_03485	COG2895	sulfate adenylyltransferase (ATP) activity
NRL03_03490	COG3273	potassium ion transport
NRL03_03490	COG0471	metal ion transport
NRL03_03495	COG0529	Catalyzes the synthesis of activated sulfate
NRL03_03530	COG0840	transmembrane signaling receptor activity
NRL03_03555	COG1136	(ABC) transporter
NRL03_03570	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
NRL03_03585	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NRL03_03590	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NRL03_03595	COG0163	prenyltransferase activity
NRL03_03610	COG1131	(ABC) transporter
NRL03_03615	COG0842	Transport permease protein
NRL03_03625	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NRL03_03630	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NRL03_03635	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NRL03_03645	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NRL03_03650	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NRL03_03655	COG1489	DNA binding
NRL03_03665	COG1643	Atp-dependent helicase
NRL03_03670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NRL03_03675	COG0346	lactoylglutathione lyase activity
NRL03_03685	COG2076	Multidrug Resistance protein
NRL03_03690	COG0583	DNA-binding transcription factor activity
NRL03_03700	COG0671	phosphoesterase, PA-phosphatase related
NRL03_03715	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NRL03_03720	COG0038	chloride channel
NRL03_03730	COG0316	Belongs to the HesB IscA family
NRL03_03765	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NRL03_03775	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NRL03_03785	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
NRL03_03790	COG1178	ABC-type Fe3 transport system permease component
NRL03_03795	COG4143	(ABC) transporter
NRL03_03810	COG0066	3-isopropylmalate dehydratase activity
NRL03_03815	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NRL03_03820	COG0473	3-isopropylmalate dehydrogenase activity
NRL03_03825	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NRL03_03835	COG0671	phosphoesterase, PA-phosphatase related
NRL03_03850	COG0028	Belongs to the TPP enzyme family
NRL03_03855	COG0440	acetolactate synthase activity
NRL03_03865	COG0857	belongs to the CobB CobQ family
NRL03_03865	COG0280	phosphate acetyltransferase
NRL03_03870	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NRL03_03875	COG3092	negative regulation of chromosome organization
NRL03_03880	COG3013	Belongs to the UPF0304 family
NRL03_03885	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NRL03_03890	COG2716	regulation of RNA biosynthetic process
NRL03_03895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NRL03_03900	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
NRL03_03905	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NRL03_03920	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
NRL03_03940	COG0784	Response regulator, receiver
NRL03_03940	COG5002	protein histidine kinase activity
NRL03_03940	COG2198	Histidine kinase
NRL03_03960	COG2198	Histidine kinase
NRL03_03960	COG2205	protein histidine kinase activity
NRL03_03960	COG0784	Response regulator, receiver
NRL03_03960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRL03_03985	COG1464	Belongs to the NlpA lipoprotein family
NRL03_03990	COG2011	ABC-type metal ion transport system permease component
NRL03_03995	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NRL03_04015	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NRL03_04015	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NRL03_04020	COG0802	atpase or kinase
NRL03_04030	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NRL03_04035	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NRL03_04040	COG1923	regulation of RNA biosynthetic process
NRL03_04045	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NRL03_04050	COG0330	HflC and HflK could
NRL03_04055	COG0330	HflC and HflK could
NRL03_04060	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
NRL03_04065	COG0142	geranyltranstransferase activity
NRL03_04070	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NRL03_04075	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NRL03_04080	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NRL03_04085	COG3314	Sporulation integral membrane protein YlbJ
NRL03_04090	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NRL03_04095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NRL03_04105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NRL03_04110	COG2967	ApaG domain
NRL03_04115	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NRL03_04120	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NRL03_04130	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
NRL03_04135	COG3178	'Phosphotransferase
NRL03_04140	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NRL03_04145	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NRL03_04150	COG2252	PERMEase
NRL03_04160	COG0488	(ABC) transporter
NRL03_04165	COG0741	lytic transglycosylase activity
NRL03_04170	COG0463	Glycosyl transferase, family 2
NRL03_04180	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NRL03_04205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRL03_04215	COG3721	Heme iron utilization protein
NRL03_04220	COG0748	coenzyme F420 binding
NRL03_04245	COG2814	Major facilitator Superfamily
NRL03_04250	COG2202	Pas domain
NRL03_04250	COG2205	protein histidine kinase activity
NRL03_04265	COG2226	methyltransferase
NRL03_04275	COG1765	OsmC-like protein
NRL03_04290	COG3954	Phosphoribulokinase
NRL03_04295	COG3089	Belongs to the UPF0270 family
NRL03_04300	COG2203	Gaf domain
NRL03_04300	COG3706	GGDEF domain
NRL03_04300	COG4251	negative regulation of phosphorylation
NRL03_04300	COG5001	Diguanylate cyclase
NRL03_04305	COG0429	hydrolase of the alpha beta-hydrolase fold
NRL03_04310	COG0784	Response regulator, receiver
NRL03_04310	COG0835	chemotaxis
NRL03_04320	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
NRL03_04325	COG1047	Peptidyl-prolyl cis-trans
NRL03_04330	COG2900	Belongs to the SlyX family
NRL03_04340	COG0545	Peptidyl-prolyl cis-trans isomerase
NRL03_04345	COG2204	response regulator
NRL03_04365	COG0737	Belongs to the 5'-nucleotidase family
NRL03_04380	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NRL03_04385	COG0506	proline dehydrogenase activity
NRL03_04385	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NRL03_04385	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NRL03_04395	COG0114	fumarate hydratase activity
NRL03_04400	COG0348	domain, Protein
NRL03_04400	COG3901	Regulator of nitric oxide reductase transcription
NRL03_04405	COG4263	nitrous-oxide reductase activity
NRL03_04420	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NRL03_04445	COG1966	Carbon starvation protein
NRL03_04450	COG3279	Response regulator of the LytR AlgR family
NRL03_04455	COG3275	phosphorelay sensor kinase activity
NRL03_04465	COG2199	diguanylate cyclase activity
NRL03_04465	COG2200	EAL domain
NRL03_04465	COG2203	Gaf domain
NRL03_04470	COG5433	transposase activity
NRL03_04495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NRL03_04505	COG1280	lysine exporter protein (LysE YggA)
NRL03_04510	COG0826	peptidase U32
NRL03_04520	COG3813	Protein conserved in bacteria
NRL03_04540	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NRL03_04565	COG0300	oxidoreductase activity
NRL03_04585	COG2610	gluconate transmembrane transporter activity
NRL03_04590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NRL03_04595	COG3622	Belongs to the hyi family
NRL03_04600	COG0235	Class ii aldolase
NRL03_04605	COG3395	kinase activity
NRL03_04610	COG2084	Dehydrogenase
NRL03_04615	COG1349	DNA-binding transcription factor activity
NRL03_04625	COG2133	pyrroloquinoline quinone binding
NRL03_04655	COG1605	Chorismate mutase
NRL03_04655	COG0077	Prephenate dehydratase
NRL03_04680	COG3272	Protein of unknown function (DUF1722)
NRL03_04685	COG0789	Transcriptional regulator
NRL03_04690	COG0415	Belongs to the DNA photolyase family
NRL03_04700	COG4221	oxidoreductase activity
NRL03_04715	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NRL03_04740	COG0783	Belongs to the Dps family
NRL03_04745	COG1151	hydroxylamine reductase activity
NRL03_04755	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NRL03_04770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRL03_04775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRL03_04780	COG0745	RESPONSE REGULATOR receiver
NRL03_04785	COG5002	protein histidine kinase activity
NRL03_04790	COG0659	secondary active sulfate transmembrane transporter activity
NRL03_04805	COG1666	GTP binding
NRL03_04815	COG2211	Major facilitator Superfamily
NRL03_04825	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NRL03_04835	COG2813	Specifically methylates the guanine in position
NRL03_04840	COG0271	Belongs to the BolA IbaG family
NRL03_04845	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NRL03_04850	COG1805	sodium ion transport
NRL03_04855	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NRL03_04860	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NRL03_04865	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NRL03_04870	COG2871	sodium ion transport
NRL03_04875	COG1477	protein flavinylation
NRL03_04890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NRL03_04895	COG0840	transmembrane signaling receptor activity
NRL03_04900	COG0583	DNA-binding transcription factor activity
NRL03_04915	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
NRL03_04925	COG0473	3-isopropylmalate dehydrogenase activity
NRL03_04930	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NRL03_04935	COG1611	Belongs to the LOG family
NRL03_04950	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NRL03_04950	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NRL03_04960	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
NRL03_04985	COG3098	single-species biofilm formation
NRL03_04990	COG0564	pseudouridine synthase activity
NRL03_05015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRL03_05015	COG1263	PTS System
NRL03_05025	COG2171	N-acyltransferase activity
NRL03_05030	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NRL03_05035	COG0024	Methionine aminopeptidase
NRL03_05040	COG0052	Belongs to the universal ribosomal protein uS2 family
NRL03_05045	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NRL03_05050	COG0528	UMP kinase activity
NRL03_05055	COG0233	cytoplasmic translational termination
NRL03_05060	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NRL03_05065	COG0575	Belongs to the CDS family
NRL03_05070	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NRL03_05075	COG0750	zinc metalloprotease
NRL03_05090	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NRL03_05095	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NRL03_05100	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NRL03_05105	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NRL03_05110	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NRL03_05115	COG0587	DNA-directed DNA polymerase activity
NRL03_05120	COG0825	malonyl-CoA metabolic process
NRL03_05135	COG0814	amino acid
NRL03_05140	COG0531	amino acid
NRL03_05165	COG0037	tRNA processing
NRL03_05170	COG3706	GGDEF domain
NRL03_05205	COG0366	Alpha amylase catalytic
NRL03_05220	COG0463	Glycosyl transferase, family 2
NRL03_05235	COG2989	Protein conserved in bacteria
NRL03_05240	COG3108	Peptidase M15
NRL03_05250	COG2860	membrane
NRL03_05260	COG1196	nuclear chromosome segregation
NRL03_05265	COG3115	cell septum assembly
NRL03_05270	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NRL03_05280	COG1328	CTP reductase activity
NRL03_05285	COG0602	queuosine metabolic process
NRL03_05310	COG1566	PFAM secretion protein HlyD family protein
NRL03_05320	COG3290	protein histidine kinase activity
NRL03_05335	COG0667	Aldo Keto reductase
NRL03_05345	COG0697	spore germination
NRL03_05360	COG3284	Transcriptional regulator
NRL03_05365	COG3706	GGDEF domain
NRL03_05370	COG0346	lactoylglutathione lyase activity
NRL03_05375	COG0745	RESPONSE REGULATOR receiver
NRL03_05380	COG5002	protein histidine kinase activity
NRL03_05390	COG4783	chaperone-mediated protein folding
NRL03_05400	COG1940	carbohydrate kinase activity
NRL03_05405	COG3142	Participates in the control of copper homeostasis
NRL03_05425	COG0545	Peptidyl-prolyl cis-trans isomerase
NRL03_05430	COG1131	(ABC) transporter
NRL03_05445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRL03_05450	COG4597	amino acid ABC transporter
NRL03_05455	COG0765	amino acid transport
NRL03_05460	COG1126	abc transporter atp-binding protein
NRL03_05470	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
NRL03_05475	COG0678	peroxiredoxin activity
NRL03_05485	COG0019	diaminopimelate decarboxylase activity
NRL03_05490	COG1115	amino acid carrier protein
NRL03_05495	COG0095	Lipoate-protein ligase
NRL03_05500	COG2233	PERMEase
NRL03_05520	COG2207	Transcriptional regulator
NRL03_05525	COG0281	malic enzyme
NRL03_05555	COG3385	transposase activity
NRL03_05560	COG0733	neurotransmitter:sodium symporter activity
NRL03_05565	COG1752	Esterase of the alpha-beta hydrolase superfamily
NRL03_05570	COG3706	GGDEF domain
NRL03_05580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRL03_05585	COG1032	radical SAM domain protein
NRL03_05605	COG0673	inositol 2-dehydrogenase activity
NRL03_05610	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NRL03_05625	COG1196	nuclear chromosome segregation
NRL03_05625	COG0741	lytic transglycosylase activity
NRL03_05625	COG0739	heme binding
NRL03_05650	COG0788	formyltetrahydrofolate deformylase activity
NRL03_05655	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NRL03_05665	COG3118	belongs to the thioredoxin family
NRL03_05680	COG0791	NLP P60 protein
NRL03_05690	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
NRL03_05705	COG1388	LysM domain
NRL03_05705	COG1376	ErfK ybiS ycfS ynhG family protein
NRL03_05740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRL03_05740	COG2205	protein histidine kinase activity
NRL03_05745	COG3384	dioxygenase
NRL03_05755	COG1283	sodium-dependent phosphate transmembrane transporter activity
NRL03_05765	COG0531	amino acid
NRL03_05770	COG0531	amino acid
NRL03_05785	COG1012	belongs to the aldehyde dehydrogenase family
NRL03_05790	COG1917	Cupin 2, conserved barrel domain protein
NRL03_05790	COG1396	sequence-specific DNA binding
NRL03_05795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRL03_05830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NRL03_05830	COG4651	solute:proton antiporter activity
NRL03_05835	COG0405	Gamma-glutamyltransferase
NRL03_05845	COG2974	May be involved in recombination
NRL03_05850	COG1247	-acetyltransferase
NRL03_05855	COG0420	3'-5' exonuclease activity
NRL03_05865	COG3038	cytochrome b561
NRL03_05870	COG2190	(PTS) system
NRL03_05880	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRL03_05885	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NRL03_05890	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NRL03_05905	COG1720	tRNA m6t6A37 methyltransferase activity
NRL03_05925	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NRL03_05930	COG4988	ABC transporter
NRL03_05945	COG0745	RESPONSE REGULATOR receiver
NRL03_05955	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NRL03_05970	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
NRL03_05975	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
NRL03_05985	COG0083	homoserine kinase activity
NRL03_05990	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NRL03_06035	COG3385	transposase activity
NRL03_06050	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NRL03_06060	COG3220	belongs to the UPF0276 family
NRL03_06095	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NRL03_06100	COG1289	transmembrane transporter activity
NRL03_06105	COG1763	Mo-molybdopterin cofactor biosynthetic process
NRL03_06110	COG0746	molybdenum cofactor guanylyltransferase activity
NRL03_06115	COG0281	malic enzyme
NRL03_06135	COG2706	6-phosphogluconolactonase activity
NRL03_06220	COG3264	Mechanosensitive ion channel
NRL03_06220	COG1196	nuclear chromosome segregation
NRL03_06230	COG2850	peptidyl-arginine hydroxylation
NRL03_06235	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NRL03_06240	COG2915	High frequency lysogenization protein hflD homolog
NRL03_06245	COG0482	sulfurtransferase activity
NRL03_06255	COG1187	pseudouridine synthase activity
NRL03_06260	COG0456	acetyltransferase
NRL03_06295	COG0538	isocitrate dehydrogenase activity
NRL03_06305	COG3048	D-serine ammonia-lyase activity
NRL03_06310	COG0583	DNA-binding transcription factor activity
NRL03_06315	COG2916	Histone family protein nucleoid-structuring protein H-NS
NRL03_06320	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NRL03_06325	COG2375	cellular response to nickel ion
NRL03_06335	COG0577	efflux transmembrane transporter activity
NRL03_06335	COG1136	(ABC) transporter
NRL03_06340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRL03_06350	COG0497	DNA recombination
NRL03_06355	COG3706	GGDEF domain
NRL03_06360	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NRL03_06365	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NRL03_06370	COG0443	Heat shock 70 kDa protein
NRL03_06375	COG0484	heat shock protein binding
NRL03_06410	COG1285	pathogenesis
NRL03_06420	COG0446	pyridine nucleotide-disulphide oxidoreductase
NRL03_06430	COG0640	Transcriptional regulator
NRL03_06460	COG0095	Lipoate-protein ligase
NRL03_06475	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRL03_06480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRL03_06490	COG0708	Exodeoxyribonuclease III
NRL03_06500	COG0745	RESPONSE REGULATOR receiver
NRL03_06515	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
NRL03_06530	COG1846	Transcriptional regulator
NRL03_06550	COG0583	DNA-binding transcription factor activity
NRL03_06555	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NRL03_06560	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NRL03_06565	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NRL03_06570	COG1845	cytochrome c oxidase, subunit III
NRL03_06575	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NRL03_06580	COG0109	protoheme IX farnesyltransferase activity
NRL03_06585	COG2814	Major facilitator Superfamily
NRL03_06590	COG5507	3-demethylubiquinone-9 3-methyltransferase
NRL03_06595	COG2175	clavaminate synthase activity
NRL03_06600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NRL03_06605	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NRL03_06610	COG4521	taurine ABC transporter
NRL03_06685	COG3385	transposase activity
NRL03_06690	COG0159	tryptophan synthase activity
NRL03_06695	COG0133	tryptophan synthase activity
NRL03_06700	COG0134	indole-3-glycerol-phosphate synthase activity
NRL03_06700	COG0135	phosphoribosylanthranilate isomerase activity
NRL03_06705	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NRL03_06710	COG0512	Glutamine amidotransferase of anthranilate synthase
NRL03_06710	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NRL03_06720	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NRL03_06725	COG0613	PHP domain protein
NRL03_06730	COG0009	L-threonylcarbamoyladenylate synthase
NRL03_06740	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NRL03_06755	COG1946	Acyl-CoA thioesterase
NRL03_06770	COG1309	transcriptional regulator
NRL03_06775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRL03_06780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRL03_06850	COG3385	transposase activity
NRL03_06865	COG0582	viral genome integration into host DNA
NRL03_06875	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NRL03_06885	COG1960	acyl-CoA dehydrogenase activity
NRL03_06890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRL03_06900	COG0469	pyruvate kinase activity
NRL03_06905	COG1737	Transcriptional regulator
NRL03_06920	COG1482	cell wall glycoprotein biosynthetic process
NRL03_06940	COG3385	transposase activity
NRL03_06945	COG2244	polysaccharide biosynthetic process
NRL03_06950	COG1216	Glycosyl transferase, family 2
NRL03_06950	COG1442	glycosyl transferase family 8
NRL03_06970	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
NRL03_06975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NRL03_07000	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NRL03_07005	COG1091	dTDP-4-dehydrorhamnose reductase activity
NRL03_07015	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
NRL03_07035	COG3132	Protein of unknown function, DUF480
NRL03_07060	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NRL03_07075	COG1278	Cold shock
NRL03_07095	COG3385	transposase activity
NRL03_07125	COG0697	spore germination
NRL03_07135	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NRL03_07150	COG4166	transmembrane transport
NRL03_07155	COG0622	Phosphoesterase
NRL03_07170	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
NRL03_07175	COG0835	chemotaxis
NRL03_07175	COG0784	Response regulator, receiver
NRL03_07180	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NRL03_07185	COG1815	bacterial-type flagellum-dependent cell motility
NRL03_07200	COG1749	Flagellar hook protein flgE
NRL03_07220	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
NRL03_07225	COG1706	bacterial-type flagellum-dependent cell motility
NRL03_07230	COG3951	Flagellar rod assembly protein muramidase FlgJ
NRL03_07230	COG1705	Flagellar rod assembly protein muramidase FlgJ
NRL03_07245	COG2239	Acts as a magnesium transporter
NRL03_07255	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NRL03_07260	COG2716	regulation of RNA biosynthetic process
NRL03_07285	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NRL03_07290	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NRL03_07295	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NRL03_07300	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NRL03_07320	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NRL03_07335	COG0590	tRNA wobble adenosine to inosine editing
NRL03_07340	COG0573	inorganic phosphate transmembrane transporter activity
NRL03_07345	COG0581	inorganic phosphate transmembrane transporter activity
NRL03_07350	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NRL03_07355	COG0704	Plays a role in the regulation of phosphate uptake
NRL03_07360	COG1253	flavin adenine dinucleotide binding
NRL03_07375	COG0531	amino acid
NRL03_07385	COG1126	abc transporter atp-binding protein
NRL03_07395	COG0765	amino acid transport
NRL03_07400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRL03_07405	COG3706	GGDEF domain
NRL03_07410	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NRL03_07430	COG1785	Belongs to the alkaline phosphatase family
NRL03_07435	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NRL03_07440	COG0477	Major facilitator Superfamily
NRL03_07445	COG0123	including yeast histone deacetylase and acetoin utilization protein
NRL03_07455	COG1199	ATP-dependent helicase activity
NRL03_07470	COG1448	Aminotransferase
NRL03_07475	COG0433	COG0433 Predicted ATPase
NRL03_07490	COG2333	competence protein COMEC
NRL03_07490	COG0658	competence protein
NRL03_07495	COG1132	(ABC) transporter
NRL03_07500	COG1663	tetraacyldisaccharide 4'-kinase activity
NRL03_07505	COG2835	tetraacyldisaccharide 4'-kinase activity
NRL03_07510	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NRL03_07515	COG2197	response regulator
NRL03_07520	COG0322	excinuclease ABC activity
NRL03_07545	COG0583	DNA-binding transcription factor activity
NRL03_07560	COG0604	alcohol dehydrogenase
NRL03_07565	COG1309	transcriptional regulator
NRL03_07570	COG2261	transglycosylase associated protein
NRL03_07575	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NRL03_07585	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NRL03_07590	COG0215	cysteine-tRNA ligase activity
NRL03_07610	COG5433	transposase activity
NRL03_07615	COG3385	transposase activity
NRL03_07625	COG3385	transposase activity
NRL03_07645	COG5433	transposase activity
NRL03_07660	COG2199	diguanylate cyclase activity
NRL03_07660	COG2203	Gaf domain
NRL03_07695	COG2119	membrane
NRL03_07700	COG0023	Translation Initiation Factor
NRL03_07710	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NRL03_07735	COG4139	cobalamin transport
NRL03_07740	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
NRL03_07745	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NRL03_07750	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NRL03_07755	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NRL03_07760	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NRL03_07765	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NRL03_07775	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NRL03_07780	COG0505	Belongs to the CarA family
NRL03_07785	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NRL03_07790	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NRL03_07795	COG3706	GGDEF domain
NRL03_07830	COG0513	Belongs to the DEAD box helicase family
NRL03_07840	COG4104	PAAR repeat-containing protein
NRL03_07865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRL03_07870	COG0765	amino acid transport
NRL03_07875	COG1126	abc transporter atp-binding protein
NRL03_07880	COG0493	'glutamate synthase
NRL03_07885	COG0070	glutamate synthase
NRL03_07885	COG0067	glutamate synthase
NRL03_07885	COG0069	glutamate synthase activity
NRL03_07890	COG1242	4 iron, 4 sulfur cluster binding
NRL03_07925	COG4584	PFAM Integrase catalytic
NRL03_07930	COG1484	DNA-dependent DNA replication
NRL03_07950	COG1113	amino acid transport
NRL03_07960	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NRL03_07965	COG0574	Belongs to the PEP-utilizing enzyme family
NRL03_07965	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NRL03_07970	COG1119	ATPase activity
NRL03_07995	COG1464	Belongs to the NlpA lipoprotein family
NRL03_08005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NRL03_08010	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NRL03_08020	COG0101	tRNA pseudouridine synthase activity
NRL03_08025	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NRL03_08030	COG0285	dihydrofolate synthase activity
NRL03_08035	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
NRL03_08040	COG2920	part of a sulfur-relay system
NRL03_08045	COG1289	transmembrane transporter activity
NRL03_08050	COG0670	Belongs to the BI1 family
NRL03_08085	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NRL03_08090	COG0840	transmembrane signaling receptor activity
NRL03_08095	COG5001	Diguanylate cyclase
NRL03_08100	COG0564	pseudouridine synthase activity
NRL03_08115	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
NRL03_08125	COG0625	glutathione transferase activity
NRL03_08140	COG0367	asparagine synthase
NRL03_08155	COG0647	UMP catabolic process
NRL03_08160	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NRL03_08170	COG1902	pentaerythritol trinitrate reductase activity
NRL03_08175	COG1253	flavin adenine dinucleotide binding
NRL03_08190	COG0247	lactate metabolic process
NRL03_08190	COG0277	FAD linked oxidase domain protein
NRL03_08200	COG2050	protein possibly involved in aromatic compounds catabolism
NRL03_08215	COG5001	Diguanylate cyclase
NRL03_08220	COG0583	DNA-binding transcription factor activity
NRL03_08225	COG2814	Major facilitator Superfamily
NRL03_08230	COG2056	Na+-H+ antiporter family
NRL03_08235	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NRL03_08250	COG0483	inositol monophosphate 1-phosphatase activity
NRL03_08260	COG0625	glutathione transferase activity
NRL03_08265	COG0625	glutathione transferase activity
NRL03_08275	COG0601	transmembrane transport
NRL03_08280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRL03_08285	COG0444	Belongs to the ABC transporter superfamily
NRL03_08290	COG2814	Major facilitator Superfamily
NRL03_08310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NRL03_08315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NRL03_08320	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NRL03_08325	COG0509	glycine decarboxylation via glycine cleavage system
NRL03_08330	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NRL03_08330	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NRL03_08355	COG3634	alkyl hydroperoxide reductase activity
NRL03_08360	COG0450	alkyl hydroperoxide reductase
NRL03_08370	COG0517	IMP dehydrogenase activity
NRL03_08375	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NRL03_08380	COG0343	queuine tRNA-ribosyltransferase activity
NRL03_08385	COG1862	Preprotein translocase
NRL03_08390	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NRL03_08395	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NRL03_08400	COG2897	thiosulfate sulfurtransferase activity
NRL03_08410	COG0826	peptidase U32
NRL03_08415	COG0826	peptidase U32
NRL03_08420	COG3154	lipid carrier protein
NRL03_08435	COG1104	cysteine desulfurase activity
NRL03_08440	COG0822	iron-sulfur transferase activity
NRL03_08450	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NRL03_08455	COG0443	Heat shock 70 kDa protein
NRL03_08460	COG0633	Ferredoxin
NRL03_08475	COG0105	UTP biosynthetic process
NRL03_08480	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NRL03_08490	COG1426	Protein conserved in bacteria
NRL03_08500	COG0124	histidyl-tRNA synthetase
NRL03_08505	COG2976	Protein conserved in bacteria
NRL03_08510	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NRL03_08515	COG1160	GTP binding
NRL03_08545	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NRL03_08550	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NRL03_08550	COG0047	phosphoribosylformylglycinamidine synthase activity
NRL03_08555	COG1007	ATP synthesis coupled electron transport
NRL03_08560	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRL03_08570	COG0713	ATP synthesis coupled electron transport
NRL03_08575	COG0839	Belongs to the complex I subunit 6 family
NRL03_08580	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRL03_08585	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NRL03_08590	COG1034	ATP synthesis coupled electron transport
NRL03_08605	COG0649	NAD binding
NRL03_08605	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRL03_08610	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRL03_08615	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRL03_08620	COG1360	Flagellar Motor Protein
NRL03_08625	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NRL03_08645	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NRL03_08655	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
NRL03_08665	COG0724	RNA recognition motif
NRL03_08670	COG4989	oxidoreductase activity
NRL03_08695	COG0745	RESPONSE REGULATOR receiver
NRL03_08700	COG0583	DNA-binding transcription factor activity
NRL03_08715	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
NRL03_08745	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NRL03_08750	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NRL03_08755	COG0539	negative regulation of cytoplasmic translation
NRL03_08760	COG0776	regulation of translation
NRL03_08770	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NRL03_08790	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NRL03_08795	COG0602	queuosine metabolic process
NRL03_08800	COG3530	Putative quorum-sensing-regulated virulence factor
NRL03_08805	COG2096	Adenosyltransferase
NRL03_08810	COG2916	Histone family protein nucleoid-structuring protein H-NS
NRL03_08815	COG1757	Na H antiporter
NRL03_08820	COG1435	thymidine kinase activity
NRL03_08850	COG1737	Transcriptional regulator
NRL03_08855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRL03_08855	COG1263	PTS System
NRL03_08855	COG2190	(PTS) system
NRL03_08860	COG2723	6-phospho-beta-galactosidase activity
NRL03_08875	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NRL03_08885	COG5433	transposase activity
NRL03_08890	COG3550	peptidyl-serine autophosphorylation
NRL03_09025	COG0745	RESPONSE REGULATOR receiver
NRL03_09030	COG0784	Response regulator, receiver
NRL03_09030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRL03_09030	COG2198	Histidine kinase
NRL03_09030	COG2205	protein histidine kinase activity
NRL03_09055	COG0411	ABC transporter
NRL03_09065	COG0829	nickel cation binding
NRL03_09070	COG0831	urea catabolic process
NRL03_09075	COG0832	Belongs to the urease beta subunit family
NRL03_09080	COG0804	urea catabolic process
NRL03_09085	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
NRL03_09095	COG0830	nickel cation binding
NRL03_09100	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NRL03_09155	COG3039	Transposase
NRL03_09165	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NRL03_09180	COG2801	Transposase and inactivated derivatives
NRL03_09245	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NRL03_09250	COG0626	cystathionine gamma-synthase activity
NRL03_09260	COG2910	NAD(P)H-binding
NRL03_09265	COG0583	DNA-binding transcription factor activity
NRL03_09270	COG4977	sequence-specific DNA binding
NRL03_09270	COG1917	Cupin 2, conserved barrel domain protein
NRL03_09275	COG2200	EAL domain
NRL03_09280	COG2199	diguanylate cyclase activity
NRL03_09280	COG2203	Gaf domain
NRL03_09285	COG4774	siderophore transport
NRL03_09295	COG0583	DNA-binding transcription factor activity
NRL03_09300	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NRL03_09310	COG0517	IMP dehydrogenase activity
NRL03_09310	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NRL03_09310	COG0617	tRNA 3'-terminal CCA addition
NRL03_09325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRL03_09330	COG3046	protein related to deoxyribodipyrimidine photolyase
NRL03_09345	COG3088	subunit of a heme lyase
NRL03_09345	COG4235	cytochrome complex assembly
NRL03_09350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NRL03_09355	COG1138	Cytochrome C-type biogenesis protein
NRL03_09360	COG3301	Polysulphide reductase, NrfD
NRL03_09365	COG0437	4 iron, 4 sulfur cluster binding
NRL03_09370	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
NRL03_09385	COG0247	lactate metabolic process
NRL03_09395	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
NRL03_09400	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NRL03_09405	COG3012	SEC-C Motif Domain Protein
NRL03_09410	COG0840	transmembrane signaling receptor activity
NRL03_09415	COG1846	Transcriptional regulator
NRL03_09415	COG1940	carbohydrate kinase activity
NRL03_09420	COG3290	protein histidine kinase activity
NRL03_09425	COG4565	transcriptional regulatory protein
NRL03_09440	COG3181	Tripartite tricarboxylate transporter family receptor
NRL03_09445	COG0741	lytic transglycosylase activity
NRL03_09445	COG0739	heme binding
NRL03_09445	COG1196	nuclear chromosome segregation
NRL03_09450	COG0569	domain protein
NRL03_09450	COG2985	domain, Protein
NRL03_09460	COG0556	nucleotide-excision repair
NRL03_09470	COG0586	Pfam SNARE associated Golgi protein
NRL03_09475	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NRL03_09480	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NRL03_09485	COG2186	Transcriptional regulator
NRL03_09490	COG2719	SpoVR family
NRL03_09495	COG2718	Belongs to the UPF0229 family
NRL03_09500	COG2766	serine protein kinase
NRL03_09510	COG0514	ATP-dependent DNA helicase (RecQ)
NRL03_09515	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NRL03_09520	COG0814	amino acid
NRL03_09550	COG0058	SHG alpha-glucan phosphorylase activity
NRL03_09560	COG0471	metal ion transport
NRL03_09565	COG3118	belongs to the thioredoxin family
NRL03_09575	COG1132	(ABC) transporter
NRL03_09580	COG1132	(ABC) transporter
NRL03_09610	COG2501	S4 domain
NRL03_09640	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NRL03_09645	COG2329	Antibiotic biosynthesis monooxygenase
NRL03_09680	COG0513	Belongs to the DEAD box helicase family
NRL03_09685	COG0386	Belongs to the glutathione peroxidase family
NRL03_09695	COG1181	Belongs to the D-alanine--D-alanine ligase family
NRL03_09700	COG3148	PFAM DTW domain containing protein
NRL03_09710	COG0730	response to heat
NRL03_09715	COG0583	DNA-binding transcription factor activity
NRL03_09735	COG3593	DNA synthesis involved in DNA repair
NRL03_09755	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NRL03_09760	COG1011	Hydrolase
NRL03_09765	COG1473	amidohydrolase
NRL03_09775	COG0205	6-phosphofructokinase activity
NRL03_09785	COG1434	Gram-negative-bacterium-type cell wall biogenesis
NRL03_09790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NRL03_09800	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
NRL03_09805	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
NRL03_09860	COG1280	lysine exporter protein (LysE YggA)
NRL03_09875	COG2824	Alkylphosphonate utilization operon protein PhnA
NRL03_09920	COG2840	Smr protein MutS2
NRL03_09925	COG2890	protein-(glutamine-N5) methyltransferase activity
NRL03_09930	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NRL03_09940	COG0513	Belongs to the DEAD box helicase family
NRL03_09945	COG5654	RES domain protein
NRL03_09955	COG0814	amino acid
NRL03_09960	COG1609	Transcriptional regulator
NRL03_09965	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRL03_09965	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRL03_09970	COG1105	Belongs to the carbohydrate kinase PfkB family
NRL03_09975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRL03_09975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRL03_09975	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
NRL03_09980	COG3313	Fe-S protein
NRL03_09985	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
NRL03_10005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NRL03_10010	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NRL03_10015	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NRL03_10025	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NRL03_10050	COG0675	Transposase, IS605 OrfB family
NRL03_10090	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NRL03_10095	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NRL03_10100	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NRL03_10105	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NRL03_10110	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NRL03_10115	COG0072	phenylalanine-tRNA ligase activity
NRL03_10115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRL03_10120	COG0776	regulation of translation
NRL03_10150	COG3300	MHYT domain
NRL03_10150	COG5001	Diguanylate cyclase
NRL03_10160	COG1609	Transcriptional regulator
NRL03_10165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRL03_10170	COG1879	ABC-type sugar transport system periplasmic component
NRL03_10175	COG1172	Belongs to the binding-protein-dependent transport system permease family
NRL03_10180	COG1129	ABC transporter
NRL03_10185	COG1869	D-ribose catabolic process
NRL03_10190	COG0625	glutathione transferase activity
NRL03_10205	COG0037	tRNA processing
NRL03_10210	COG0589	response to stress
NRL03_10215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NRL03_10230	COG2217	Heavy metal translocating P-type atpase
NRL03_10240	COG2010	Cytochrome c
NRL03_10255	COG3278	Belongs to the heme-copper respiratory oxidase family
NRL03_10265	COG1956	GAF domain-containing protein
NRL03_10270	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
NRL03_10280	COG0308	aminopeptidase N
NRL03_10290	COG2902	Dehydrogenase
NRL03_10295	COG0167	dihydroorotate dehydrogenase activity
NRL03_10305	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NRL03_10305	COG0116	Belongs to the methyltransferase superfamily
NRL03_10315	COG0488	(ABC) transporter
NRL03_10330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NRL03_10335	COG1067	ATP-dependent peptidase activity
NRL03_10455	COG5433	transposase activity
NRL03_10480	COG1484	DNA-dependent DNA replication
NRL03_10485	COG4584	PFAM Integrase catalytic
NRL03_10610	COG3141	response to X-ray
NRL03_10620	COG2995	paraquat-inducible protein a
NRL03_10625	COG3008	intermembrane lipid transfer
NRL03_10630	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NRL03_10630	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
NRL03_10645	COG0084	hydrolase, TatD family'
NRL03_10650	COG0470	DNA polymerase III
NRL03_10655	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NRL03_10660	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NRL03_10665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NRL03_10670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NRL03_10675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NRL03_10680	COG1028	Short-chain dehydrogenase reductase Sdr
NRL03_10690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NRL03_10695	COG0416	fatty acid biosynthetic process
NRL03_10700	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NRL03_10705	COG1399	metal-binding, possibly nucleic acid-binding protein
NRL03_10720	COG0564	pseudouridine synthase activity
NRL03_10725	COG1530	ribonuclease E activity
NRL03_10730	COG0306	phosphate transporter
NRL03_10735	COG0717	Belongs to the dCTP deaminase family
NRL03_10740	COG0572	uridine kinase
NRL03_10745	COG0489	protein tyrosine kinase activity
NRL03_10750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRL03_10750	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRL03_10760	COG1254	Belongs to the acylphosphatase family
NRL03_10765	COG0840	transmembrane signaling receptor activity
NRL03_10770	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NRL03_10790	COG0709	Synthesizes selenophosphate from selenide and ATP
NRL03_10795	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
NRL03_10800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRL03_10825	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NRL03_10835	COG1643	Atp-dependent helicase
NRL03_10840	COG0517	IMP dehydrogenase activity
NRL03_10840	COG0617	tRNA 3'-terminal CCA addition
NRL03_10840	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NRL03_10845	COG2197	response regulator
NRL03_10895	COG3385	transposase activity
NRL03_10910	COG3314	Sporulation integral membrane protein YlbJ
NRL03_10920	COG0583	DNA-binding transcription factor activity
NRL03_10925	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NRL03_10935	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NRL03_10940	COG2832	Protein of unknown function (DUF454)
NRL03_10945	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NRL03_10955	COG0697	spore germination
NRL03_10970	COG0318	PFAM AMP-dependent synthetase and ligase
NRL03_10975	COG0596	Alpha beta hydrolase
NRL03_10985	COG1214	PFAM Peptidase M22, glycoprotease
NRL03_10990	COG1199	ATP-dependent helicase activity
NRL03_11000	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NRL03_11005	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NRL03_11010	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NRL03_11015	COG0131	Imidazoleglycerol-phosphate dehydratase
NRL03_11015	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NRL03_11020	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NRL03_11025	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NRL03_11030	COG3437	response regulator, receiver
NRL03_11035	COG2199	diguanylate cyclase activity
NRL03_11040	COG0784	Response regulator, receiver
NRL03_11040	COG2198	Histidine kinase
NRL03_11040	COG2205	protein histidine kinase activity
NRL03_11045	COG0107	imidazoleglycerol-phosphate synthase activity
NRL03_11050	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NRL03_11050	COG0140	phosphoribosyl-ATP diphosphatase activity
NRL03_11060	COG5433	transposase activity
NRL03_11070	COG3385	transposase activity
NRL03_11080	COG3385	transposase activity
NRL03_11090	COG0318	PFAM AMP-dependent synthetase and ligase
NRL03_11095	COG3134	Outer membrane lipoprotein
NRL03_11110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRL03_11130	COG4681	YaeQ
NRL03_11140	COG1024	Enoyl-CoA hydratase
NRL03_11140	COG1250	3-hydroxyacyl-CoA dehydrogenase
NRL03_11145	COG0183	Belongs to the thiolase family
NRL03_11150	COG0714	Associated with various cellular activities
NRL03_11180	COG1595	DNA-templated transcription, initiation
NRL03_11190	COG2067	long-chain fatty acid transport protein
NRL03_11195	COG2067	long-chain fatty acid transport protein
NRL03_11200	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
NRL03_11215	COG1301	dicarboxylic acid transport
NRL03_11220	COG3123	guanosine phosphorylase activity
NRL03_11225	COG1760	l-serine dehydratase
NRL03_11230	COG1760	l-serine dehydratase
NRL03_11235	COG2951	lytic endotransglycosylase activity
NRL03_11240	COG3100	YcgL domain-containing protein
NRL03_11245	COG0850	regulation of cytokinetic process
NRL03_11250	COG2894	cell division
NRL03_11255	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NRL03_11260	COG3099	Belongs to the UPF0263 family
NRL03_11265	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NRL03_11280	COG2996	Protein conserved in bacteria
NRL03_11285	COG0675	Transposase, IS605 OrfB family
NRL03_11315	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NRL03_11320	COG0697	spore germination
NRL03_11325	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NRL03_11330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRL03_11345	COG0307	riboflavin synthase, alpha
NRL03_11355	COG0534	Mate efflux family protein
NRL03_11385	COG0417	DNA replication proofreading
NRL03_11400	COG1560	Kdo2-lipid A biosynthetic process
NRL03_11405	COG1560	Kdo2-lipid A biosynthetic process
NRL03_11415	COG0583	DNA-binding transcription factor activity
NRL03_11420	COG0673	inositol 2-dehydrogenase activity
NRL03_11425	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NRL03_11440	COG0583	DNA-binding transcription factor activity
NRL03_11450	COG2723	6-phospho-beta-galactosidase activity
NRL03_11455	COG0583	DNA-binding transcription factor activity
NRL03_11465	COG0243	molybdopterin cofactor binding
NRL03_11470	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NRL03_11485	COG0583	DNA-binding transcription factor activity
NRL03_11490	COG1879	ABC-type sugar transport system periplasmic component
NRL03_11495	COG1129	ABC transporter
NRL03_11500	COG1172	Belongs to the binding-protein-dependent transport system permease family
NRL03_11505	COG1172	Belongs to the binding-protein-dependent transport system permease family
NRL03_11555	COG2003	Belongs to the UPF0758 family
NRL03_11585	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NRL03_11605	COG0730	response to heat
NRL03_11615	COG1028	Short-chain dehydrogenase reductase Sdr
NRL03_11625	COG1024	Enoyl-CoA hydratase
NRL03_11630	COG1024	Enoyl-CoA hydratase
NRL03_11635	COG1960	acyl-CoA dehydrogenase activity
NRL03_11645	COG1960	acyl-CoA dehydrogenase activity
NRL03_11650	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NRL03_11655	COG1024	Enoyl-CoA hydratase
NRL03_11680	COG1584	GPR1 FUN34 yaaH family protein
NRL03_11685	COG3228	Belongs to the MtfA family
NRL03_11695	COG1115	amino acid carrier protein
NRL03_11700	COG1024	Enoyl-CoA hydratase
NRL03_11715	COG3162	membrane
NRL03_11720	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NRL03_11725	COG0488	(ABC) transporter
NRL03_11730	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NRL03_11735	COG0776	regulation of translation
NRL03_11740	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NRL03_11745	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NRL03_11750	COG0740	serine-type endopeptidase activity
NRL03_11755	COG0544	peptidyl-prolyl cis-trans isomerase activity
NRL03_11765	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
NRL03_11770	COG4591	ABC-type transport system involved in lipoprotein release permease component
NRL03_11775	COG1136	(ABC) transporter
NRL03_11780	COG4591	ABC-type transport system involved in lipoprotein release permease component
NRL03_11790	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NRL03_11795	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
NRL03_11810	COG0697	spore germination
NRL03_11820	COG2062	phosphohistidine phosphatase, SixA
NRL03_11840	COG1846	Transcriptional regulator
NRL03_11860	COG3385	transposase activity
NRL03_11865	COG0519	Catalyzes the synthesis of GMP from XMP
NRL03_11865	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NRL03_11870	COG0517	IMP dehydrogenase activity
NRL03_11870	COG0516	GMP reductase activity
NRL03_11880	COG1874	Beta-galactosidase
NRL03_11880	COG0366	Alpha amylase catalytic
NRL03_11890	COG1570	exodeoxyribonuclease VII activity
NRL03_11900	COG2885	chlorophyll binding
NRL03_11920	COG2154	pterin-4-alpha-carbinolamine dehydratase
NRL03_11930	COG3768	UPF0283 membrane protein
NRL03_11935	COG3106	COG3106 Predicted ATPase
NRL03_11950	COG1842	Phage shock protein A
NRL03_11955	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NRL03_11970	COG4171	peptide transport system, permease
NRL03_11980	COG4172	Belongs to the ABC transporter superfamily
NRL03_11990	COG1609	Transcriptional regulator
NRL03_11995	COG1263	PTS System
NRL03_11995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRL03_12000	COG2723	6-phospho-beta-galactosidase activity
NRL03_12005	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NRL03_12010	COG1286	toxin biosynthetic process
NRL03_12015	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NRL03_12020	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NRL03_12025	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NRL03_12030	COG1674	ftsk spoiiie
NRL03_12030	COG0531	amino acid
NRL03_12040	COG0686	Belongs to the AlaDH PNT family
NRL03_12045	COG0492	ferredoxin-NADP+ reductase activity
NRL03_12050	COG3706	GGDEF domain
NRL03_12055	COG3134	Outer membrane lipoprotein
NRL03_12060	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NRL03_12065	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NRL03_12070	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NRL03_12075	COG0542	response to heat
NRL03_12080	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NRL03_12085	COG1278	Cold shock
NRL03_12090	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NRL03_12095	COG2076	Multidrug Resistance protein
NRL03_12110	COG1944	ATP diphosphatase activity
NRL03_12115	COG2116	formate transmembrane transporter activity
NRL03_12120	COG1882	Formate acetyltransferase
NRL03_12125	COG2983	Belongs to the UPF0260 family
NRL03_12140	COG2801	Transposase and inactivated derivatives
NRL03_12145	COG3385	transposase activity
NRL03_12150	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NRL03_12155	COG0045	succinate-CoA ligase (ADP-forming) activity
NRL03_12160	COG0508	dehydrogenase complex catalyzes the overall conversion of
NRL03_12165	COG0567	Dehydrogenase, E1 component
NRL03_12180	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NRL03_12185	COG2009	succinate dehydrogenase
NRL03_12205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NRL03_12210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRL03_12210	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NRL03_12220	COG3069	C4-dicarboxylate transmembrane transporter activity
NRL03_12235	COG1451	nucleotide metabolic process
NRL03_12250	COG0254	rRNA binding
NRL03_12255	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NRL03_12265	COG1172	Belongs to the binding-protein-dependent transport system permease family
NRL03_12270	COG1129	ABC transporter
NRL03_12275	COG1879	ABC-type sugar transport system periplasmic component
NRL03_12280	COG1069	ribulokinase activity
NRL03_12290	COG2160	L-arabinose isomerase activity
NRL03_12295	COG0583	DNA-binding transcription factor activity
NRL03_12300	COG0436	Aminotransferase
NRL03_12305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NRL03_12320	COG0392	lysyltransferase activity
NRL03_12320	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NRL03_12325	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NRL03_12560	COG2314	TM2 domain
NRL03_12575	COG0592	DNA-directed DNA polymerase activity
NRL03_12610	COG0582	viral genome integration into host DNA
NRL03_12615	COG2925	Exonuclease
NRL03_12625	COG3345	alpha-galactosidase
NRL03_12630	COG1380	Effector of murein hydrolase LrgA
NRL03_12635	COG1346	cytolysis
NRL03_12640	COG0295	cytidine deaminase activity
NRL03_12645	COG1022	Amp-dependent synthetase and ligase
NRL03_12660	COG0861	Integral membrane protein TerC family
NRL03_12665	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NRL03_12670	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NRL03_12675	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NRL03_12715	COG4771	TonB-dependent receptor
NRL03_12720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRL03_12725	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRL03_12730	COG1120	ATPase activity
NRL03_12740	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NRL03_12745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NRL03_12755	COG1028	Short-chain dehydrogenase reductase Sdr
NRL03_12760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NRL03_12765	COG1535	isochorismatase
NRL03_12765	COG3433	isochorismatase activity
NRL03_12770	COG1021	2,3-dihydroxybenzoate-AMP ligase
NRL03_12795	COG5001	Diguanylate cyclase
NRL03_12795	COG3300	MHYT domain
NRL03_12810	COG0840	transmembrane signaling receptor activity
NRL03_12815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRL03_12820	COG3788	relative of glutathione S-transferase, MAPEG superfamily
NRL03_12825	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NRL03_12830	COG0563	adenylate kinase activity
NRL03_12835	COG0326	Molecular chaperone. Has ATPase activity
NRL03_12840	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NRL03_12855	COG0659	secondary active sulfate transmembrane transporter activity
NRL03_12870	COG2308	Evidence 4 Homologs of previously reported genes of
NRL03_12905	COG0672	)-iron permease
NRL03_12930	COG2814	Major facilitator Superfamily
NRL03_12950	COG1136	(ABC) transporter
NRL03_12955	COG0577	efflux transmembrane transporter activity
NRL03_12985	COG1139	Iron-sulfur cluster binding protein
NRL03_12990	COG0247	lactate metabolic process
NRL03_12995	COG1620	l-lactate permease
NRL03_13000	COG0583	DNA-binding transcription factor activity
NRL03_13025	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NRL03_13030	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NRL03_13030	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NRL03_13035	COG0527	aspartate kinase activity
NRL03_13045	COG1368	sulfuric ester hydrolase activity
NRL03_13050	COG0393	Putative heavy-metal-binding
NRL03_13060	COG1252	NADH dehydrogenase
NRL03_13065	COG3150	esterase
NRL03_13070	COG1164	Oligoendopeptidase f
NRL03_13075	COG1164	Oligoendopeptidase f
NRL03_13080	COG2354	Protein conserved in bacteria
NRL03_13095	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NRL03_13100	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NRL03_13135	COG0537	adenosine 5'-monophosphoramidase activity
NRL03_13150	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NRL03_13170	COG1301	dicarboxylic acid transport
NRL03_13185	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NRL03_13190	COG0861	Integral membrane protein TerC family
NRL03_13200	COG0444	Belongs to the ABC transporter superfamily
NRL03_13205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRL03_13210	COG0601	transmembrane transport
NRL03_13220	COG2095	MarC family integral membrane protein
NRL03_13225	COG1012	belongs to the aldehyde dehydrogenase family
NRL03_13225	COG1454	alcohol dehydrogenase
NRL03_13235	COG3275	phosphorelay sensor kinase activity
NRL03_13240	COG3279	Response regulator of the LytR AlgR family
NRL03_13245	COG1966	Carbon starvation protein
NRL03_13250	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
NRL03_13250	COG3264	Mechanosensitive ion channel
NRL03_13255	COG0675	Transposase, IS605 OrfB family
NRL03_13270	COG1566	PFAM secretion protein HlyD family protein
NRL03_13275	COG1061	Type III restriction enzyme res subunit
NRL03_13280	COG2027	D-alanyl-D-alanine carboxypeptidase
NRL03_13285	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NRL03_13295	COG0436	Aminotransferase
NRL03_13300	COG1288	antiporter activity
NRL03_13310	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NRL03_13325	COG0840	transmembrane signaling receptor activity
NRL03_13335	COG0697	spore germination
NRL03_13340	COG4657	Part of a membrane complex involved in electron transport
NRL03_13345	COG2878	Part of a membrane complex involved in electron transport
NRL03_13355	COG4658	electron transport chain
NRL03_13360	COG4659	FMN binding
NRL03_13365	COG4660	Part of a membrane complex involved in electron transport
NRL03_13370	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NRL03_13375	COG0346	lactoylglutathione lyase activity
NRL03_13390	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NRL03_13400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NRL03_13405	COG1086	Polysaccharide biosynthesis protein
NRL03_13410	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NRL03_13420	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
NRL03_13425	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NRL03_13440	COG2089	acid synthase
NRL03_13495	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NRL03_13515	COG3385	transposase activity
NRL03_13530	COG0301	tRNA thio-modification
NRL03_13530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRL03_13540	COG4953	penicillin-binding protein 1C
NRL03_13545	COG2373	Large extracellular alpha-helical protein
NRL03_13550	COG0446	pyridine nucleotide-disulphide oxidoreductase
NRL03_13560	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NRL03_13570	COG4160	amino acid transport
NRL03_13580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRL03_13590	COG2431	L-lysine efflux transmembrane transporter activity
NRL03_13595	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NRL03_13600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRL03_13625	COG1393	Belongs to the ArsC family
NRL03_13635	COG4783	chaperone-mediated protein folding
NRL03_13640	COG0425	Belongs to the sulfur carrier protein TusA family
NRL03_13655	COG0596	Alpha beta hydrolase
NRL03_13665	COG3842	ATPase activity
NRL03_13670	COG3833	ABC-type maltose transport systems, permease component
NRL03_13675	COG1175	transmembrane transport
NRL03_13685	COG3081	Nucleoid-associated protein
NRL03_13690	COG3082	Protein of unknown function (DUF1414)
NRL03_13695	COG3083	sulfuric ester hydrolase activity
NRL03_13700	COG4771	TonB-dependent receptor
NRL03_13705	COG1770	oligopeptidase
NRL03_13725	COG4574	serine-type endopeptidase inhibitor activity
NRL03_13730	COG3085	chromosome segregation
NRL03_13740	COG0287	Prephenate dehydrogenase
NRL03_13740	COG1605	Chorismate mutase
NRL03_13745	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NRL03_13750	COG0584	glycerophosphoryl diester phosphodiesterase
NRL03_13760	COG1349	DNA-binding transcription factor activity
NRL03_13765	COG2271	Major facilitator Superfamily
NRL03_13780	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NRL03_13785	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NRL03_13790	COG0583	DNA-binding transcription factor activity
NRL03_13810	COG0656	L-ascorbic acid biosynthetic process
NRL03_13815	COG2814	Major facilitator Superfamily
NRL03_13825	COG1294	oxidase, subunit
NRL03_13835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRL03_13845	COG2979	Protein of unknown function (DUF533)
NRL03_13865	COG0583	DNA-binding transcription factor activity
NRL03_13875	COG2807	transmembrane transport
NRL03_13880	COG1187	pseudouridine synthase activity
NRL03_13885	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NRL03_13895	COG0675	Transposase, IS605 OrfB family
NRL03_13915	COG1061	Type III restriction enzyme res subunit
NRL03_13940	COG1166	arginine decarboxylase activity
NRL03_13945	COG2195	Cleaves the N-terminal amino acid of tripeptides
NRL03_13960	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NRL03_13975	COG0583	DNA-binding transcription factor activity
NRL03_13985	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NRL03_13990	COG0840	transmembrane signaling receptor activity
NRL03_13995	COG0302	gtp cyclohydrolase
NRL03_14005	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NRL03_14010	COG2267	carboxylic ester hydrolase activity
NRL03_14015	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NRL03_14030	COG0314	molybdopterin synthase activity
NRL03_14035	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NRL03_14040	COG0315	cyclic pyranopterin monophosphate synthase activity
NRL03_14045	COG0521	Mo-molybdopterin cofactor biosynthetic process
NRL03_14050	COG3005	denitrification pathway
NRL03_14060	COG0348	domain, Protein
NRL03_14065	COG0437	4 iron, 4 sulfur cluster binding
NRL03_14070	COG0243	molybdopterin cofactor binding
NRL03_14080	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NRL03_14080	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
NRL03_14085	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NRL03_14090	COG3850	Histidine kinase
NRL03_14095	COG2197	response regulator
NRL03_14120	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NRL03_14130	COG0121	glutamine amidotransferase
NRL03_14135	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NRL03_14140	COG1960	acyl-CoA dehydrogenase activity
NRL03_14155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NRL03_14160	COG0328	RNA-DNA hybrid ribonuclease activity
NRL03_14165	COG2226	methyltransferase
NRL03_14170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRL03_14180	COG0741	lytic transglycosylase activity
NRL03_14180	COG1388	LysM domain
NRL03_14195	COG1607	acyl-coa hydrolase
NRL03_14210	COG0741	lytic transglycosylase activity
NRL03_14220	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NRL03_14240	COG2911	Protein conserved in bacteria
NRL03_14245	COG0729	surface antigen
NRL03_14255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NRL03_14265	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NRL03_14270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NRL03_14275	COG4134	Bacterial extracellular solute-binding protein
NRL03_14285	COG4136	ATPase activity
NRL03_14290	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NRL03_14295	COG2951	lytic endotransglycosylase activity
NRL03_14300	COG1846	Transcriptional regulator
NRL03_14310	COG0033	Phosphoglucomutase
NRL03_14315	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
NRL03_14320	COG0596	Alpha beta hydrolase
NRL03_14335	COG0716	FMN binding
NRL03_14345	COG0735	belongs to the Fur family
NRL03_14355	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NRL03_14365	COG2190	(PTS) system
NRL03_14365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRL03_14365	COG1263	PTS System
NRL03_14370	COG0363	glucosamine-6-phosphate deaminase activity
NRL03_14375	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NRL03_14380	COG1846	Transcriptional regulator
NRL03_14380	COG1940	carbohydrate kinase activity
NRL03_14385	COG2194	sulfuric ester hydrolase activity
NRL03_14390	COG0217	transcriptional regulatory protein
NRL03_14395	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NRL03_14400	COG1801	Protein of unknown function DUF72
NRL03_14405	COG4106	trans-aconitate 2-methyltransferase activity
NRL03_14410	COG0500	methyltransferase
NRL03_14430	COG0583	DNA-binding transcription factor activity
NRL03_14435	COG0791	NLP P60 protein
NRL03_14450	COG1309	transcriptional regulator
NRL03_14485	COG0534	Mate efflux family protein
NRL03_14495	COG2841	Protein conserved in bacteria
NRL03_14500	COG0674	pyruvate-flavodoxin oxidoreductase activity
NRL03_14500	COG1013	pyruvate-flavodoxin oxidoreductase activity
NRL03_14500	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NRL03_14500	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NRL03_14510	COG0633	Ferredoxin
NRL03_14510	COG3217	Mosc domain protein beta barrel domain protein
NRL03_14510	COG0633	Ferredoxin
NRL03_14510	COG3217	Mosc domain protein beta barrel domain protein
NRL03_14515	COG0501	Belongs to the peptidase M48B family
NRL03_14520	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NRL03_14525	COG2226	methyltransferase
NRL03_14525	COG1073	alpha beta
NRL03_14530	COG0156	8-amino-7-oxononanoate synthase activity
NRL03_14535	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NRL03_14555	COG0017	Asparaginyl-tRNA synthetase
NRL03_14560	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NRL03_14570	COG1473	amidohydrolase
NRL03_14575	COG3069	C4-dicarboxylate transmembrane transporter activity
NRL03_14585	COG1393	Belongs to the ArsC family
NRL03_14590	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NRL03_14595	COG1876	peptidase activity
NRL03_14605	COG3263	regulation of cellular component size
NRL03_14615	COG1280	lysine exporter protein (LysE YggA)
NRL03_14640	COG1957	nucleoside hydrolase
NRL03_14645	COG0564	pseudouridine synthase activity
NRL03_14655	COG1454	alcohol dehydrogenase
NRL03_14660	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NRL03_14665	COG0702	epimerase
NRL03_14670	COG2914	Belongs to the UPF0125 (RnfH) family
NRL03_14675	COG2867	negative regulation of translational initiation
NRL03_14680	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NRL03_14715	COG0246	Mannitol dehydrogenase
NRL03_14720	COG2721	sulfolactate sulfo-lyase activity
NRL03_14730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRL03_14735	COG0800	Aldolase
NRL03_14750	COG3153	acetyltransferase
NRL03_14780	COG0259	pyridoxamine-phosphate oxidase activity
NRL03_14795	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NRL03_14795	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NRL03_14800	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NRL03_14815	COG0457	Tetratricopeptide repeat
NRL03_14825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NRL03_14830	COG1138	Cytochrome C-type biogenesis protein
NRL03_14835	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
NRL03_14840	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NRL03_14845	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NRL03_14850	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NRL03_14865	COG0835	chemotaxis
NRL03_14875	COG1192	Involved in chromosome partitioning
NRL03_14880	COG1360	Flagellar Motor Protein
NRL03_14885	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NRL03_14895	COG0643	Histidine kinase
NRL03_14895	COG0784	Response regulator, receiver
NRL03_14895	COG2198	Histidine kinase
NRL03_14900	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
NRL03_14925	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NRL03_14935	COG1684	flagellar biosynthetic protein fliR
NRL03_14990	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NRL03_15000	COG1677	Flagellar hook-basal body complex protein FliE
NRL03_15005	COG3385	transposase activity
NRL03_15015	COG1393	Belongs to the ArsC family
NRL03_15020	COG0798	PFAM Bile acid sodium symporter
NRL03_15025	COG0640	Transcriptional regulator
NRL03_15105	COG2194	sulfuric ester hydrolase activity
NRL03_15115	COG3385	transposase activity
NRL03_15135	COG3385	transposase activity
NRL03_15150	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NRL03_15155	COG5642	Protein of unknown function (DUF2384)
NRL03_15185	COG5433	transposase activity
NRL03_15195	COG3039	Transposase
NRL03_15200	COG5001	Diguanylate cyclase
NRL03_15200	COG3447	MASE1 domain protein
NRL03_15200	COG5002	protein histidine kinase activity
NRL03_15205	COG3039	Transposase
NRL03_15210	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NRL03_15225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRL03_15230	COG0444	Belongs to the ABC transporter superfamily
NRL03_15235	COG4608	Belongs to the ABC transporter superfamily
NRL03_15245	COG2971	BadF BadG BcrA BcrD
NRL03_15255	COG0840	transmembrane signaling receptor activity
NRL03_15275	COG3724	N-succinylarginine dihydrolase activity
NRL03_15280	COG0616	signal peptide processing
NRL03_15285	COG1028	Short-chain dehydrogenase reductase Sdr
NRL03_15300	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NRL03_15310	COG0583	DNA-binding transcription factor activity
NRL03_15315	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NRL03_15320	COG1881	PFAM PEBP family protein
NRL03_15330	COG3408	Glycogen debranching enzyme
NRL03_15330	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
NRL03_15335	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NRL03_15340	COG0739	heme binding
NRL03_15345	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NRL03_15365	COG2801	Transposase and inactivated derivatives
NRL03_15375	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NRL03_15385	COG3091	SprT-like family
NRL03_15395	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NRL03_15400	COG0189	ligase activity
NRL03_15410	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NRL03_15430	COG1115	amino acid carrier protein
NRL03_15435	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NRL03_15450	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NRL03_15460	COG1301	dicarboxylic acid transport
NRL03_15465	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NRL03_15470	COG2912	Transglutaminase-like superfamily
NRL03_15480	COG2890	protein-(glutamine-N5) methyltransferase activity
NRL03_15485	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NRL03_15490	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NRL03_15495	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NRL03_15500	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NRL03_15510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NRL03_15515	COG0193	aminoacyl-tRNA hydrolase activity
NRL03_15520	COG0012	GTP binding
NRL03_15570	COG0490	domain, Protein
NRL03_15570	COG0471	metal ion transport
NRL03_15580	COG0657	acetylesterase activity
NRL03_15595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRL03_15625	COG3385	transposase activity
NRL03_15650	COG1012	belongs to the aldehyde dehydrogenase family
NRL03_15660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NRL03_15675	COG0180	Tryptophanyl-tRNA synthetase
NRL03_15680	COG0546	phosphoglycolate phosphatase activity
NRL03_15685	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NRL03_15690	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NRL03_15700	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NRL03_15705	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NRL03_15735	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NRL03_15740	COG0583	DNA-binding transcription factor activity
NRL03_15750	COG3385	transposase activity
NRL03_15760	COG0583	DNA-binding transcription factor activity
NRL03_15775	COG0739	heme binding
NRL03_15785	COG3264	Mechanosensitive ion channel
NRL03_15785	COG1511	domain protein
NRL03_15790	COG0584	glycerophosphoryl diester phosphodiesterase
NRL03_15800	COG1053	succinate dehydrogenase
NRL03_15805	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NRL03_15810	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
NRL03_15815	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
NRL03_15830	COG3214	Protein conserved in bacteria
NRL03_15835	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NRL03_15855	COG0300	oxidoreductase activity
NRL03_15875	COG0189	ligase activity
NRL03_15875	COG4067	protein conserved in archaea
NRL03_15880	COG0516	GMP reductase activity
NRL03_15890	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NRL03_15895	COG2011	ABC-type metal ion transport system permease component
NRL03_15900	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NRL03_15905	COG1464	Belongs to the NlpA lipoprotein family
NRL03_15920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NRL03_15930	COG2199	diguanylate cyclase activity
NRL03_15940	COG2199	diguanylate cyclase activity
NRL03_15945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRL03_15960	COG1278	Cold shock
NRL03_15965	COG1335	isochorismatase
NRL03_15970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NRL03_15975	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NRL03_15980	COG1702	phosphate starvation-inducible protein PhoH
NRL03_15985	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NRL03_15990	COG4535	Mg2 and Co2 transporter CorC
NRL03_16000	COG0815	Transfers the fatty acyl group on membrane lipoproteins
NRL03_16005	COG2888	peptidyl-tyrosine sulfation
NRL03_16010	COG0495	leucyl-tRNA aminoacylation
NRL03_16030	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NRL03_16035	COG0799	negative regulation of ribosome biogenesis
NRL03_16040	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NRL03_16045	COG0768	penicillin binding
NRL03_16050	COG0772	Belongs to the SEDS family
NRL03_16055	COG2951	lytic endotransglycosylase activity
NRL03_16060	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NRL03_16065	COG1686	Belongs to the peptidase S11 family
NRL03_16070	COG2921	Belongs to the UPF0250 family
NRL03_16075	COG0321	lipoyl(octanoyl) transferase activity
NRL03_16080	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NRL03_16090	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NRL03_16105	COG0789	Transcriptional regulator
NRL03_16120	COG1970	mechanosensitive ion channel activity
NRL03_16125	COG4974	Belongs to the 'phage' integrase family
NRL03_16135	COG0312	modulator of DNA gyrase
NRL03_16145	COG0312	modulator of DNA gyrase
NRL03_16165	COG0826	peptidase U32
NRL03_16170	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NRL03_16175	COG1422	Protein of unknown function (DUF1090)
NRL03_16180	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NRL03_16185	COG2211	Major facilitator Superfamily
NRL03_16190	COG1185	polyribonucleotide nucleotidyltransferase activity
NRL03_16195	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NRL03_16200	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NRL03_16205	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NRL03_16210	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NRL03_16215	COG0195	Participates in both transcription termination and antitermination
NRL03_16220	COG0779	Required for maturation of 30S ribosomal subunits
NRL03_16235	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NRL03_16240	COG0149	triose-phosphate isomerase activity
NRL03_16245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NRL03_16250	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NRL03_16260	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NRL03_16265	COG1534	Rna-binding protein
NRL03_16280	COG1360	Flagellar Motor Protein
NRL03_16290	COG1722	exodeoxyribonuclease VII activity
NRL03_16295	COG0142	geranyltranstransferase activity
NRL03_16300	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NRL03_16305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRL03_16310	COG0601	transmembrane transport
NRL03_16320	COG4172	Belongs to the ABC transporter superfamily
NRL03_16325	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NRL03_16330	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NRL03_16335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NRL03_16340	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NRL03_16355	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NRL03_16355	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NRL03_16360	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NRL03_16370	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NRL03_16380	COG3381	protein complex oligomerization
NRL03_16395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NRL03_16400	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NRL03_16405	COG0511	ligase activity, forming carbon-carbon bonds
NRL03_16410	COG0439	Biotin carboxylase
NRL03_16415	COG3924	membrane
NRL03_16420	COG4145	pantothenate transmembrane transporter activity
NRL03_16425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRL03_16425	COG1263	PTS System
NRL03_16425	COG2190	(PTS) system
NRL03_16430	COG0583	DNA-binding transcription factor activity
NRL03_16435	COG0604	alcohol dehydrogenase
NRL03_16440	COG2264	protein methyltransferase activity
NRL03_16445	COG0110	maltose O-acetyltransferase activity
NRL03_16460	COG0778	Nitroreductase
NRL03_16465	COG0446	pyridine nucleotide-disulphide oxidoreductase
NRL03_16465	COG1902	pentaerythritol trinitrate reductase activity
NRL03_16470	COG0616	signal peptide processing
NRL03_16490	COG3139	Protein of unknown function (DUF1315)
NRL03_16495	COG0252	asparaginase activity
NRL03_16500	COG0786	glutamate:sodium symporter activity
NRL03_16515	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NRL03_16525	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NRL03_16530	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NRL03_16535	COG0175	sulfate reduction
NRL03_16540	COG2113	Glycine betaine
NRL03_16545	COG4176	ABC-type proline glycine betaine transport system permease component
NRL03_16550	COG4175	Glycine betaine
NRL03_16560	COG3610	response to peptide
NRL03_16565	COG2966	Psort location CytoplasmicMembrane, score
NRL03_16575	COG0521	Mo-molybdopterin cofactor biosynthetic process
NRL03_16595	COG2313	pseudouridylate synthase activity
NRL03_16600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRL03_16605	COG2146	nitrite reductase [NAD(P)H] activity
NRL03_16605	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NRL03_16610	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NRL03_16610	COG2146	nitrite reductase [NAD(P)H] activity
NRL03_16615	COG1116	anion transmembrane transporter activity
NRL03_16620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NRL03_16625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NRL03_16625	COG1116	anion transmembrane transporter activity
NRL03_16635	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NRL03_16635	COG1648	precorrin-2 dehydrogenase activity
NRL03_16640	COG0243	molybdopterin cofactor binding
NRL03_16665	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NRL03_16680	COG1073	alpha beta
NRL03_16685	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
NRL03_16690	COG2195	Cleaves the N-terminal amino acid of tripeptides
NRL03_16695	COG4608	Belongs to the ABC transporter superfamily
NRL03_16700	COG0444	Belongs to the ABC transporter superfamily
NRL03_16710	COG4239	(ABC) transporter, permease
NRL03_16715	COG4174	ABC transporter (Permease)
NRL03_16720	COG4206	TonB-dependent receptor
NRL03_16730	COG0811	peptide transport
NRL03_16735	COG0811	peptide transport
NRL03_16740	COG0848	biopolymer transport protein
NRL03_16790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NRL03_16795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NRL03_16800	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NRL03_16805	COG0840	transmembrane signaling receptor activity
NRL03_16815	COG1278	Cold shock
NRL03_16855	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NRL03_16860	COG1162	GTPase activity
NRL03_16865	COG0688	phosphatidylethanolamine metabolic process
NRL03_16870	COG4628	conserved protein (DUF2132)
NRL03_16900	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
NRL03_16925	COG1132	(ABC) transporter
NRL03_16935	COG2897	thiosulfate sulfurtransferase activity
NRL03_16940	COG2066	Belongs to the glutaminase family
NRL03_16945	COG3171	Protein conserved in bacteria
NRL03_16950	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NRL03_16955	COG2234	aminopeptidase activity
NRL03_16955	COG4935	Belongs to the peptidase S8 family
NRL03_16960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRL03_16965	COG2200	EAL domain
NRL03_16970	COG1090	epimerase
NRL03_16975	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
NRL03_16980	COG4181	ATPase activity
NRL03_16985	COG2755	lipolytic protein G-D-S-L family
NRL03_16990	COG0784	Response regulator, receiver
NRL03_16990	COG0835	chemotaxis
NRL03_17000	COG0516	GMP reductase activity
NRL03_17000	COG0517	IMP dehydrogenase activity
NRL03_17005	COG0488	(ABC) transporter
NRL03_17015	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NRL03_17040	COG3039	Transposase
NRL03_17045	COG0789	Transcriptional regulator
NRL03_17055	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NRL03_17065	COG0668	transmembrane transport
NRL03_17075	COG2731	YhcH YjgK YiaL family protein
NRL03_17085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRL03_17090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRL03_17095	COG3227	Zinc metalloprotease (Elastase)
NRL03_17100	COG0583	DNA-binding transcription factor activity
NRL03_17105	COG0477	Major facilitator Superfamily
NRL03_17125	COG0569	domain protein
NRL03_17125	COG2985	domain, Protein
NRL03_17130	COG1272	protein, Hemolysin III
NRL03_17135	COG0076	glutamate decarboxylase activity
NRL03_17140	COG2917	probably involved in intracellular septation
NRL03_17145	COG2350	Protein conserved in bacteria
NRL03_17150	COG3385	transposase activity
NRL03_17160	COG1555	photosystem II stabilization
NRL03_17165	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NRL03_17170	COG3104	oligopeptide transport
NRL03_17175	COG0745	RESPONSE REGULATOR receiver
NRL03_17210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRL03_17225	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NRL03_17230	COG1280	lysine exporter protein (LysE YggA)
NRL03_17280	COG2205	protein histidine kinase activity
NRL03_17285	COG0745	RESPONSE REGULATOR receiver
NRL03_17290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRL03_17295	COG0577	efflux transmembrane transporter activity
NRL03_17295	COG1136	(ABC) transporter
NRL03_17305	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
NRL03_17340	COG2199	diguanylate cyclase activity
NRL03_17340	COG2203	Gaf domain
NRL03_17345	COG0513	Belongs to the DEAD box helicase family
NRL03_17375	COG3385	transposase activity
NRL03_17380	COG3039	Transposase
NRL03_17420	COG0154	amidase activity
NRL03_17425	COG2957	Belongs to the agmatine deiminase family
NRL03_17440	COG1902	pentaerythritol trinitrate reductase activity
NRL03_17470	COG5001	Diguanylate cyclase
NRL03_17470	COG5002	protein histidine kinase activity
NRL03_17475	COG2425	protein containing a von Willebrand factor type A (vWA) domain
NRL03_17490	COG5433	transposase activity
NRL03_17495	COG0456	acetyltransferase
NRL03_17505	COG1022	Amp-dependent synthetase and ligase
NRL03_17515	COG1794	racemase activity, acting on amino acids and derivatives
NRL03_17530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRL03_17545	COG0733	neurotransmitter:sodium symporter activity
NRL03_17555	COG0733	neurotransmitter:sodium symporter activity
NRL03_17570	COG0561	phosphatase activity
NRL03_17600	COG1846	Transcriptional regulator
NRL03_17605	COG2130	NADP-dependent
NRL03_17635	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NRL03_17640	COG1640	4-alpha-glucanotransferase
NRL03_17645	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NRL03_17655	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NRL03_17660	COG0840	transmembrane signaling receptor activity
NRL03_17735	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
NRL03_17740	COG2885	chlorophyll binding
NRL03_17745	COG0823	Involved in the tonB-independent uptake of proteins
NRL03_17760	COG0811	peptide transport
NRL03_17765	COG0824	Thioesterase
NRL03_17770	COG3790	cyd operon protein YbgE
NRL03_17775	COG4890	Cyd operon protein YbgT
NRL03_17780	COG1294	oxidase, subunit
NRL03_17785	COG1271	oxidase subunit
NRL03_17795	COG2255	four-way junction helicase activity
NRL03_17800	COG0632	four-way junction helicase activity
NRL03_17805	COG0840	transmembrane signaling receptor activity
NRL03_17810	COG0442	prolyl-tRNA aminoacylation
NRL03_17815	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NRL03_17820	COG4221	oxidoreductase activity
NRL03_17835	COG1024	Enoyl-CoA hydratase
NRL03_17845	COG0110	maltose O-acetyltransferase activity
NRL03_17855	COG4166	transmembrane transport
NRL03_17865	COG0840	transmembrane signaling receptor activity
NRL03_17870	COG0513	Belongs to the DEAD box helicase family
NRL03_17905	COG0457	Tetratricopeptide repeat
NRL03_17905	COG3118	belongs to the thioredoxin family
NRL03_17910	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NRL03_17915	COG1215	transferase activity, transferring glycosyl groups
NRL03_17920	COG1215	transferase activity, transferring glycosyl groups
NRL03_17925	COG1215	transferase activity, transferring glycosyl groups
NRL03_17940	COG2194	sulfuric ester hydrolase activity
NRL03_17950	COG1448	Aminotransferase
NRL03_17965	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NRL03_17970	COG1328	CTP reductase activity
NRL03_17985	COG0543	2 iron, 2 sulfur cluster binding
NRL03_17985	COG0633	Ferredoxin
NRL03_18000	COG0840	transmembrane signaling receptor activity
NRL03_18005	COG3397	chitin binding
NRL03_18010	COG0583	DNA-binding transcription factor activity
NRL03_18015	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NRL03_18020	COG4208	sulfate ABC transporter
NRL03_18025	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NRL03_18035	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NRL03_18070	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NRL03_18075	COG0564	pseudouridine synthase activity
NRL03_18095	COG0459	protein refolding
NRL03_18100	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NRL03_18105	COG0534	Mate efflux family protein
NRL03_18110	COG3030	protein affecting phage T7 exclusion by the F plasmid
NRL03_18115	COG1027	Aspartate ammonia-lyase
NRL03_18120	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NRL03_18130	COG2918	glutathione biosynthetic process
NRL03_18135	COG0612	Peptidase, M16
NRL03_18140	COG1238	metal cluster binding
NRL03_18180	COG0359	binds to the 23S rRNA
NRL03_18185	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NRL03_18190	COG0360	Binds together with S18 to 16S ribosomal RNA
NRL03_18195	COG1914	H( )-stimulated, divalent metal cation uptake system
NRL03_18205	COG2153	protein acetylation
NRL03_18215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NRL03_18220	COG0557	exoribonuclease II activity
NRL03_18225	COG3706	GGDEF domain
NRL03_18230	COG1854	S-ribosylhomocysteine lyase activity
NRL03_18245	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NRL03_18245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NRL03_18275	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NRL03_18280	COG1047	Peptidyl-prolyl cis-trans
NRL03_18285	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NRL03_18290	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NRL03_18295	COG0196	riboflavin kinase activity
NRL03_18300	COG0728	peptidoglycan biosynthetic process
NRL03_18305	COG0268	Binds directly to 16S ribosomal RNA
NRL03_18310	COG0640	Transcriptional regulator
NRL03_18315	COG0583	DNA-binding transcription factor activity
NRL03_18325	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NRL03_18330	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NRL03_18335	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NRL03_18345	COG1051	belongs to the nudix hydrolase family
NRL03_18360	COG0335	large ribosomal subunit rRNA binding
NRL03_18365	COG0336	Belongs to the RNA methyltransferase TrmD family
NRL03_18370	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NRL03_18375	COG0228	four-way junction DNA binding
NRL03_18380	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NRL03_18385	COG4137	Cytochrome C assembly protein
NRL03_18390	COG4536	flavin adenine dinucleotide binding
NRL03_18400	COG1017	nitric oxide dioxygenase activity
NRL03_18400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NRL03_18405	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
NRL03_18410	COG0039	L-malate dehydrogenase activity
NRL03_18415	COG4160	amino acid transport
NRL03_18420	COG4215	(ABC) transporter
NRL03_18425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRL03_18430	COG1126	abc transporter atp-binding protein
NRL03_18435	COG1438	arginine binding
NRL03_18440	COG2837	iron assimilation
NRL03_18445	COG3842	ATPase activity
NRL03_18460	COG0347	Belongs to the P(II) protein family
NRL03_18475	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRL03_18480	COG0583	DNA-binding transcription factor activity
NRL03_18495	COG1929	Belongs to the glycerate kinase type-1 family
NRL03_18500	COG2610	gluconate transmembrane transporter activity
NRL03_18505	COG3835	regulator
NRL03_18510	COG3112	Uncharacterised protein family (UPF0231)
NRL03_18530	COG1872	DUF167
NRL03_18535	COG0762	integral membrane protein
NRL03_18540	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NRL03_18545	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NRL03_18560	COG3022	response to hydroperoxide
NRL03_18565	COG0513	Belongs to the DEAD box helicase family
NRL03_18570	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NRL03_18590	COG0735	belongs to the Fur family
NRL03_18595	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NRL03_18605	COG3385	transposase activity
NRL03_18615	COG0776	regulation of translation
NRL03_18620	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
NRL03_18630	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NRL03_18645	COG0560	Phosphoserine phosphatase
NRL03_18655	COG5001	Diguanylate cyclase
NRL03_18655	COG3447	MASE1 domain protein
NRL03_18655	COG5002	protein histidine kinase activity
NRL03_18660	COG0813	purine-nucleoside phosphorylase activity
NRL03_18665	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NRL03_18670	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NRL03_18675	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NRL03_18685	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRL03_18690	COG0084	hydrolase, TatD family'
NRL03_18695	COG2165	general secretion pathway protein
NRL03_18710	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NRL03_18715	COG0004	ammonium transporteR
NRL03_18735	COG0795	lipopolysaccharide-transporting ATPase activity
NRL03_18740	COG0795	lipopolysaccharide-transporting ATPase activity
NRL03_18745	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NRL03_18755	COG0525	valine-tRNA ligase activity
NRL03_18760	COG1253	flavin adenine dinucleotide binding
NRL03_18765	COG0586	Pfam SNARE associated Golgi protein
NRL03_18770	COG1686	Belongs to the peptidase S11 family
NRL03_18810	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NRL03_18815	COG0527	aspartate kinase activity
NRL03_18820	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NRL03_18825	COG2137	regulation of response to DNA damage stimulus
NRL03_18830	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NRL03_18835	COG1546	Belongs to the CinA family
NRL03_18845	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NRL03_18895	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NRL03_18900	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NRL03_18915	COG5433	transposase activity
NRL03_18920	COG0477	Major facilitator Superfamily
NRL03_18925	COG0523	cobalamin synthesis protein
NRL03_18935	COG1280	lysine exporter protein (LysE YggA)
NRL03_18945	COG2200	EAL domain
NRL03_18950	COG1049	propionate catabolic process, 2-methylcitrate cycle
NRL03_18955	COG1752	Esterase of the alpha-beta hydrolase superfamily
NRL03_18960	COG0840	transmembrane signaling receptor activity
NRL03_18970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NRL03_18975	COG0508	dehydrogenase complex catalyzes the overall conversion of
NRL03_18980	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NRL03_18985	COG2186	Transcriptional regulator
NRL03_19010	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NRL03_19015	COG1459	type II secretion system
NRL03_19020	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NRL03_19030	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
NRL03_19035	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
NRL03_19040	COG0494	nUDIX hydrolase
NRL03_19055	COG0653	protein targeting
NRL03_19065	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NRL03_19070	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NRL03_19075	COG0849	cell division
NRL03_19080	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NRL03_19085	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NRL03_19090	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NRL03_19095	COG0772	Belongs to the SEDS family
NRL03_19100	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NRL03_19105	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NRL03_19110	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NRL03_19115	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NRL03_19120	COG0768	penicillin binding
NRL03_19125	COG3116	cell division
NRL03_19130	COG0275	rRNA processing
NRL03_19135	COG2001	Belongs to the MraZ family
NRL03_19150	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NRL03_19155	COG3107	peptidoglycan biosynthetic process
NRL03_19160	COG0792	nuclease activity
NRL03_19165	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NRL03_19170	COG2823	Periplasmic or secreted lipoprotein
NRL03_19175	COG2969	positive regulation of protein catabolic process
NRL03_19180	COG0625	glutathione transferase activity
NRL03_19185	COG2857	Cytochrome c1
NRL03_19190	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NRL03_19195	COG0723	plastoquinol--plastocyanin reductase activity
NRL03_19200	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NRL03_19205	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NRL03_19210	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NRL03_19220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NRL03_19225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NRL03_19255	COG3964	amidohydrolase
NRL03_19275	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRL03_19280	COG1660	Displays ATPase and GTPase activities
NRL03_19285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRL03_19295	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NRL03_19300	COG1137	ATPase activity
NRL03_19305	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NRL03_19315	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NRL03_19320	COG0517	IMP dehydrogenase activity
NRL03_19320	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NRL03_19325	COG1127	ABC transporter
NRL03_19330	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NRL03_19335	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NRL03_19340	COG2854	intermembrane phospholipid transfer
NRL03_19350	COG5007	Belongs to the BolA IbaG family
NRL03_19355	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NRL03_19365	COG1494	fructose-1,6-bisphosphatase
NRL03_19395	COG1733	regulation of RNA biosynthetic process
NRL03_19415	COG3932	Exopolysaccharide synthesis, ExoD
NRL03_19435	COG3385	transposase activity
NRL03_19455	COG0582	viral genome integration into host DNA
NRL03_19480	COG0189	ligase activity
NRL03_19485	COG0642	Histidine kinase
NRL03_19505	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NRL03_19510	COG0352	thiamine-phosphate diphosphorylase activity
NRL03_19515	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NRL03_19525	COG2022	thiamine diphosphate biosynthetic process
NRL03_19530	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NRL03_19540	COG5433	transposase activity
NRL03_19545	COG3385	transposase activity
NRL03_19555	COG1715	Restriction endonuclease
NRL03_19565	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NRL03_19590	COG3171	Protein conserved in bacteria
NRL03_19600	COG1484	DNA-dependent DNA replication
NRL03_19605	COG4584	PFAM Integrase catalytic
NRL03_19620	COG2321	neutral zinc metallopeptidase
NRL03_19630	COG0477	Major facilitator Superfamily
NRL03_19645	COG0312	modulator of DNA gyrase
NRL03_19650	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NRL03_19655	COG3164	Protein of unknown function
NRL03_19660	COG1530	ribonuclease E activity
NRL03_19665	COG0424	maF-like protein
NRL03_19670	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NRL03_19675	COG1792	Involved in formation and maintenance of cell shape
NRL03_19680	COG1077	Cell shape determining protein MreB Mrl
NRL03_19720	COG2200	EAL domain
NRL03_19725	COG0387	Pfam Sodium calcium exchanger
NRL03_19730	COG2986	histidine ammonia-lyase
NRL03_19735	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NRL03_19740	COG0010	Belongs to the arginase family
NRL03_19745	COG1228	amidohydrolase
NRL03_19755	COG2188	Transcriptional regulator
NRL03_19760	COG0288	reversible hydration of carbon dioxide
NRL03_19775	COG2177	Part of the ABC transporter FtsEX involved in
NRL03_19780	COG2884	Cell division ATP-binding protein ftsE
NRL03_19785	COG0552	protein localization to endoplasmic reticulum
NRL03_19790	COG0742	ribosomal rna small subunit methyltransferase
NRL03_19815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRL03_19825	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NRL03_19835	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NRL03_19845	COG2095	MarC family integral membrane protein
NRL03_19855	COG1301	dicarboxylic acid transport
NRL03_19865	COG0583	DNA-binding transcription factor activity
NRL03_19880	COG3714	YhhN family
NRL03_19895	COG2358	TRAP transporter, solute receptor (TAXI family
NRL03_19900	COG1770	oligopeptidase
NRL03_19915	COG4221	oxidoreductase activity
NRL03_19920	COG0583	DNA-binding transcription factor activity
NRL03_19925	COG2249	NAD(P)H dehydrogenase (quinone) activity
NRL03_19945	COG1484	DNA-dependent DNA replication
NRL03_19950	COG4584	PFAM Integrase catalytic
NRL03_19985	COG0203	ribosomal protein L17
NRL03_19990	COG0202	RNA polymerase activity
NRL03_19995	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NRL03_20000	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NRL03_20005	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NRL03_20010	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NRL03_20015	COG0201	protein transport
NRL03_20020	COG0200	Binds to the 23S rRNA
NRL03_20025	COG1841	ribosomal large subunit assembly
NRL03_20030	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NRL03_20035	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NRL03_20040	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NRL03_20045	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NRL03_20050	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NRL03_20055	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NRL03_20060	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NRL03_20065	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NRL03_20070	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NRL03_20075	COG0255	Belongs to the universal ribosomal protein uL29 family
NRL03_20080	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NRL03_20085	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NRL03_20090	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NRL03_20095	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NRL03_20100	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NRL03_20105	COG0089	rRNA binding
NRL03_20110	COG0088	Forms part of the polypeptide exit tunnel
NRL03_20115	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NRL03_20120	COG0051	transcription antitermination factor activity, RNA binding
NRL03_20130	COG2205	protein histidine kinase activity
NRL03_20140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NRL03_20145	COG2183	response to ionizing radiation
NRL03_20160	COG0596	Alpha beta hydrolase
NRL03_20165	COG1040	competence protein
NRL03_20170	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NRL03_20170	COG0316	Belongs to the HesB IscA family
NRL03_20175	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NRL03_20180	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
NRL03_20185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRL03_20190	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NRL03_20195	COG4942	peptidase
NRL03_20205	COG1609	Transcriptional regulator
NRL03_20220	COG0800	Aldolase
NRL03_20225	COG0129	dihydroxy-acid dehydratase activity
NRL03_20230	COG3265	gluconokinase activity
NRL03_20235	COG2610	gluconate transmembrane transporter activity
NRL03_20240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRL03_20245	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NRL03_20255	COG0456	acetyltransferase
NRL03_20265	COG1490	D-aminoacyl-tRNA deacylase activity
NRL03_20270	COG1295	ribonuclease BN
NRL03_20275	COG1217	gtp-binding protein TYPA
NRL03_20280	COG0174	glutamine synthetase
NRL03_20290	COG3852	Histidine kinase
NRL03_20300	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NRL03_20305	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NRL03_20315	COG3078	GTPase activator activity
NRL03_20320	COG5433	transposase activity
NRL03_20330	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NRL03_20335	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NRL03_20340	COG0408	coproporphyrinogen oxidase activity
NRL03_20345	COG0009	L-threonylcarbamoyladenylate synthase
NRL03_20350	COG0551	DNA topoisomerase type I activity
NRL03_20355	COG2922	Belongs to the Smg family
NRL03_20360	COG0758	DNA mediated transformation
NRL03_20370	COG0242	peptide deformylase activity
NRL03_20375	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NRL03_20380	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NRL03_20380	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NRL03_20385	COG0569	domain protein
NRL03_20390	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NRL03_20395	COG1322	Protein conserved in bacteria
NRL03_20415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRL03_20425	COG0519	Catalyzes the synthesis of GMP from XMP
NRL03_20425	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NRL03_20435	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NRL03_20440	COG1396	sequence-specific DNA binding
NRL03_20445	COG1012	belongs to the aldehyde dehydrogenase family
NRL03_20455	COG2962	Rard protein
NRL03_20465	COG1280	lysine exporter protein (LysE YggA)
NRL03_20505	COG0583	DNA-binding transcription factor activity
NRL03_20540	COG5433	transposase activity
NRL03_20550	COG0210	DNA helicase
NRL03_20555	COG1744	ABC transporter substrate-binding protein PnrA-like
NRL03_20560	COG3845	ABC transporter
NRL03_20565	COG4603	Belongs to the binding-protein-dependent transport system permease family
NRL03_20570	COG1079	Belongs to the binding-protein-dependent transport system permease family
NRL03_20580	COG3039	Transposase
NRL03_20585	COG0583	DNA-binding transcription factor activity
NRL03_20610	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NRL03_20615	COG0385	Bile acid
NRL03_20620	COG0531	amino acid
NRL03_20625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRL03_20630	COG0531	amino acid
NRL03_20635	COG2731	YhcH YjgK YiaL family protein
NRL03_20640	COG3250	beta-galactosidase activity
NRL03_20645	COG1609	Transcriptional regulator
NRL03_20680	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
NRL03_20685	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NRL03_20690	COG1739	Uncharacterized protein family UPF0029
NRL03_20695	COG0006	proline dipeptidase activity
NRL03_20700	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NRL03_20705	COG1250	3-hydroxyacyl-CoA dehydrogenase
NRL03_20705	COG1024	Enoyl-CoA hydratase
NRL03_20710	COG0183	Belongs to the thiolase family
NRL03_20725	COG1653	transport
NRL03_20740	COG0425	Belongs to the sulfur carrier protein TusA family
NRL03_20745	COG0251	oxidation-reduction process
NRL03_20765	COG2885	chlorophyll binding
NRL03_20775	COG1335	isochorismatase
NRL03_20780	COG2818	Glycosylase
NRL03_20785	COG0752	glycyl-tRNA synthetase alpha subunit
NRL03_20790	COG0751	glycine-tRNA ligase activity
NRL03_20800	COG3039	Transposase
NRL03_20835	COG0814	amino acid
NRL03_20840	COG0814	amino acid
NRL03_20845	COG3033	Beta-eliminating lyase
NRL03_20850	COG5433	transposase activity
NRL03_20855	COG3385	transposase activity
NRL03_20860	COG0348	domain, Protein
NRL03_20870	COG0446	pyridine nucleotide-disulphide oxidoreductase
NRL03_20875	COG0426	domain, Protein
NRL03_20875	COG1773	rubredoxin
NRL03_20880	COG3604	Transcriptional regulator
NRL03_20885	COG1609	Transcriptional regulator
NRL03_20925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRL03_20945	COG2960	long-chain fatty acid transporting porin activity
NRL03_20955	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NRL03_20970	COG3118	belongs to the thioredoxin family
NRL03_20975	COG0513	Belongs to the DEAD box helicase family
NRL03_20980	COG0248	Ppx GppA phosphatase
NRL03_20990	COG0742	ribosomal rna small subunit methyltransferase
NRL03_21005	COG3385	transposase activity
NRL03_21025	COG0084	hydrolase, TatD family'
NRL03_21030	COG0805	protein transport
NRL03_21035	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NRL03_21040	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NRL03_21045	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NRL03_21050	COG3165	ubiquinone biosynthetic process from chorismate
NRL03_21060	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NRL03_21065	COG0402	S-adenosylhomocysteine deaminase activity
NRL03_21095	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NRL03_21100	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NRL03_21100	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NRL03_21105	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
NRL03_21110	COG3074	FtsZ-dependent cytokinesis
NRL03_21120	COG1045	serine acetyltransferase
NRL03_21130	COG0745	RESPONSE REGULATOR receiver
NRL03_21135	COG2205	protein histidine kinase activity
NRL03_21140	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NRL03_21145	COG0534	Mate efflux family protein
NRL03_21160	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NRL03_21165	COG2937	Belongs to the GPAT DAPAT family
NRL03_21170	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NRL03_21175	COG3161	chorismate lyase activity
NRL03_21180	COG1580	Controls the rotational direction of flagella during chemotaxis
NRL03_21200	COG1609	Transcriptional regulator
NRL03_21235	COG3306	glycosyltransferase involved in LPS biosynthesis
NRL03_21255	COG0438	transferase activity, transferring glycosyl groups
NRL03_21260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NRL03_21270	COG0156	8-amino-7-oxononanoate synthase activity
NRL03_21280	COG1063	alcohol dehydrogenase
NRL03_21300	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NRL03_21305	COG2166	iron-sulfur cluster assembly
NRL03_21310	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NRL03_21345	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NRL03_21350	COG0848	biopolymer transport protein
NRL03_21355	COG0811	peptide transport
NRL03_21360	COG0811	peptide transport
NRL03_21370	COG2771	luxR family
NRL03_21375	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NRL03_21380	COG1349	DNA-binding transcription factor activity
NRL03_21385	COG0745	RESPONSE REGULATOR receiver
NRL03_21390	COG2205	protein histidine kinase activity
NRL03_21410	COG4452	Inner membrane protein CreD
NRL03_21415	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NRL03_21420	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NRL03_21425	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NRL03_21430	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NRL03_21435	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NRL03_21440	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NRL03_21445	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NRL03_21455	COG0356	it plays a direct role in the translocation of protons across the membrane
NRL03_21465	COG1475	DNA binding
NRL03_21470	COG1192	Involved in chromosome partitioning
NRL03_21475	COG0357	Ribosomal RNA small subunit methyltransferase G
NRL03_21480	COG0445	tRNA wobble uridine modification
NRL03_21485	COG0716	FMN binding
NRL03_21490	COG4774	siderophore transport
NRL03_21495	COG4615	Cyclic peptide transporter
NRL03_21500	COG1120	ATPase activity
NRL03_21505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NRL03_21515	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NRL03_21520	COG0706	membrane insertase activity
NRL03_21525	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NRL03_21530	COG0594	ribonuclease P activity
NRL03_21535	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NRL03_21545	COG1126	abc transporter atp-binding protein