locus-tag	class	description
IL332_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IL332_00010	COG0592	DNA-directed DNA polymerase activity
IL332_00025	COG2207	Transcriptional regulator
IL332_00030	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IL332_00035	COG0071	Belongs to the small heat shock protein (HSP20) family
IL332_00040	COG0071	Belongs to the small heat shock protein (HSP20) family
IL332_00045	COG3977	Valine--pyruvate aminotransferase
IL332_00060	COG2814	Major facilitator Superfamily
IL332_00065	COG0745	RESPONSE REGULATOR receiver
IL332_00070	COG2205	protein histidine kinase activity
IL332_00090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IL332_00095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IL332_00095	COG4191	Histidine kinase
IL332_00100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IL332_00105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IL332_00110	COG1309	transcriptional regulator
IL332_00140	COG0561	phosphatase activity
IL332_00145	COG2267	carboxylic ester hydrolase activity
IL332_00150	COG0110	maltose O-acetyltransferase activity
IL332_00155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IL332_00160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IL332_00165	COG1758	RNA polymerase activity
IL332_00175	COG0859	PFAM glycosyl transferase family 9
IL332_00180	COG3642	lipopolysaccharide core region biosynthetic process
IL332_00220	COG0589	response to stress
IL332_00225	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IL332_00230	COG3706	GGDEF domain
IL332_00235	COG1528	Iron-storage protein
IL332_00240	COG2081	HI0933 family
IL332_00245	COG2223	nitrite transmembrane transporter activity
IL332_00250	COG1280	lysine exporter protein (LysE YggA)
IL332_00265	COG3188	usher protein
IL332_00285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IL332_00285	COG2205	protein histidine kinase activity
IL332_00295	COG3275	phosphorelay sensor kinase activity
IL332_00300	COG3279	Response regulator of the LytR AlgR family
IL332_00305	COG2223	nitrite transmembrane transporter activity
IL332_00310	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IL332_00315	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IL332_00365	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IL332_00370	COG2166	iron-sulfur cluster assembly
IL332_00375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IL332_00395	COG1063	alcohol dehydrogenase
IL332_00400	COG0156	8-amino-7-oxononanoate synthase activity
IL332_00410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IL332_00455	COG1609	Transcriptional regulator
IL332_00470	COG1580	Controls the rotational direction of flagella during chemotaxis
IL332_00475	COG3161	chorismate lyase activity
IL332_00480	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IL332_00485	COG2937	Belongs to the GPAT DAPAT family
IL332_00490	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IL332_00505	COG0534	Mate efflux family protein
IL332_00510	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IL332_00515	COG2205	protein histidine kinase activity
IL332_00520	COG0745	RESPONSE REGULATOR receiver
IL332_00530	COG1045	serine acetyltransferase
IL332_00540	COG3074	FtsZ-dependent cytokinesis
IL332_00545	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
IL332_00550	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IL332_00550	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IL332_00555	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IL332_00590	COG1609	Transcriptional regulator
IL332_00595	COG3250	beta-galactosidase activity
IL332_00600	COG2731	YhcH YjgK YiaL family protein
IL332_00605	COG0531	amino acid
IL332_00610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IL332_00620	COG0385	Bile acid
IL332_00650	COG0583	DNA-binding transcription factor activity
IL332_00655	COG1079	Belongs to the binding-protein-dependent transport system permease family
IL332_00660	COG4603	Belongs to the binding-protein-dependent transport system permease family
IL332_00665	COG3845	ABC transporter
IL332_00670	COG1744	ABC transporter substrate-binding protein PnrA-like
IL332_00685	COG0210	DNA helicase
IL332_00700	COG1943	Transposase
IL332_00705	COG0583	DNA-binding transcription factor activity
IL332_00740	COG0583	DNA-binding transcription factor activity
IL332_00755	COG1280	lysine exporter protein (LysE YggA)
IL332_00765	COG2962	Rard protein
IL332_00775	COG1012	belongs to the aldehyde dehydrogenase family
IL332_00780	COG1396	sequence-specific DNA binding
IL332_00785	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IL332_00795	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IL332_00795	COG0519	Catalyzes the synthesis of GMP from XMP
IL332_00805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IL332_00825	COG1322	Protein conserved in bacteria
IL332_00830	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IL332_00835	COG0569	domain protein
IL332_00840	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IL332_00840	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IL332_00845	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IL332_00850	COG0242	peptide deformylase activity
IL332_00860	COG0758	DNA mediated transformation
IL332_00865	COG2922	Belongs to the Smg family
IL332_00870	COG0551	DNA topoisomerase type I activity
IL332_00875	COG0009	L-threonylcarbamoyladenylate synthase
IL332_00880	COG0408	coproporphyrinogen oxidase activity
IL332_00885	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IL332_00890	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IL332_00900	COG3078	GTPase activator activity
IL332_00910	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IL332_00915	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IL332_00925	COG3852	Histidine kinase
IL332_00935	COG0174	glutamine synthetase
IL332_00940	COG1217	gtp-binding protein TYPA
IL332_00950	COG1490	D-aminoacyl-tRNA deacylase activity
IL332_00960	COG0456	acetyltransferase
IL332_00970	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IL332_00975	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IL332_00980	COG2610	gluconate transmembrane transporter activity
IL332_00985	COG3265	gluconokinase activity
IL332_00990	COG0129	dihydroxy-acid dehydratase activity
IL332_00995	COG0800	Aldolase
IL332_01010	COG1609	Transcriptional regulator
IL332_01020	COG4942	peptidase
IL332_01025	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IL332_01030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IL332_01035	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IL332_01040	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IL332_01045	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IL332_01045	COG0316	Belongs to the HesB IscA family
IL332_01050	COG1040	competence protein
IL332_01055	COG0596	Alpha beta hydrolase
IL332_01070	COG2183	response to ionizing radiation
IL332_01075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IL332_01085	COG2205	protein histidine kinase activity
IL332_01095	COG0051	transcription antitermination factor activity, RNA binding
IL332_01100	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IL332_01105	COG0088	Forms part of the polypeptide exit tunnel
IL332_01110	COG0089	rRNA binding
IL332_01115	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IL332_01120	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IL332_01125	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IL332_01130	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IL332_01135	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IL332_01140	COG0255	Belongs to the universal ribosomal protein uL29 family
IL332_01145	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IL332_01150	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IL332_01155	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IL332_01160	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IL332_01165	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IL332_01170	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IL332_01175	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IL332_01180	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IL332_01185	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IL332_01190	COG1841	ribosomal large subunit assembly
IL332_01195	COG0200	Binds to the 23S rRNA
IL332_01200	COG0201	protein transport
IL332_01205	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IL332_01210	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IL332_01215	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IL332_01220	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IL332_01225	COG0202	RNA polymerase activity
IL332_01230	COG0203	ribosomal protein L17
IL332_01285	COG0583	DNA-binding transcription factor activity
IL332_01290	COG4221	oxidoreductase activity
IL332_01305	COG1770	oligopeptidase
IL332_01310	COG2358	TRAP transporter, solute receptor (TAXI family
IL332_01325	COG3714	YhhN family
IL332_01340	COG0583	DNA-binding transcription factor activity
IL332_01350	COG1301	dicarboxylic acid transport
IL332_01360	COG2095	MarC family integral membrane protein
IL332_01370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IL332_01380	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IL332_01390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IL332_01415	COG0742	ribosomal rna small subunit methyltransferase
IL332_01420	COG0552	protein localization to endoplasmic reticulum
IL332_01425	COG2884	Cell division ATP-binding protein ftsE
IL332_01430	COG2177	Part of the ABC transporter FtsEX involved in
IL332_01440	COG0288	reversible hydration of carbon dioxide
IL332_01445	COG2188	Transcriptional regulator
IL332_01450	COG1228	amidohydrolase
IL332_01455	COG0010	Belongs to the arginase family
IL332_01460	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IL332_01465	COG2986	histidine ammonia-lyase
IL332_01470	COG0387	Pfam Sodium calcium exchanger
IL332_01475	COG2200	EAL domain
IL332_01525	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IL332_01530	COG1459	type II secretion system
IL332_01575	COG1077	Cell shape determining protein MreB Mrl
IL332_01580	COG1792	Involved in formation and maintenance of cell shape
IL332_01585	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IL332_01590	COG0424	maF-like protein
IL332_01595	COG1530	ribonuclease E activity
IL332_01600	COG3164	Protein of unknown function
IL332_01605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IL332_01610	COG0312	modulator of DNA gyrase
IL332_01625	COG0477	Major facilitator Superfamily
IL332_01635	COG2321	neutral zinc metallopeptidase
IL332_01670	COG0189	ligase activity
IL332_01680	COG0745	RESPONSE REGULATOR receiver
IL332_01695	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IL332_01700	COG0352	thiamine-phosphate diphosphorylase activity
IL332_01705	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IL332_01715	COG2022	thiamine diphosphate biosynthetic process
IL332_01720	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IL332_01735	COG0110	maltose O-acetyltransferase activity
IL332_01750	COG3932	Exopolysaccharide synthesis, ExoD
IL332_01770	COG1733	regulation of RNA biosynthetic process
IL332_01795	COG2226	methyltransferase
IL332_01805	COG1494	fructose-1,6-bisphosphatase
IL332_01815	COG3071	HemY protein
IL332_01820	COG2959	enzyme of heme biosynthesis
IL332_01830	COG0181	hydroxymethylbilane synthase activity
IL332_01835	COG3072	Adenylate cyclase
IL332_01840	COG0400	carboxylic ester hydrolase activity
IL332_01845	COG1965	Belongs to the frataxin family
IL332_01855	COG0019	diaminopimelate decarboxylase activity
IL332_01860	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IL332_01875	COG1011	Hydrolase
IL332_01885	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IL332_01890	COG0561	phosphatase activity
IL332_01900	COG1988	membrane-bound metal-dependent
IL332_01905	COG1058	Belongs to the CinA family
IL332_01905	COG1546	Belongs to the CinA family
IL332_01915	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IL332_01925	COG1522	sequence-specific DNA binding
IL332_01930	COG1368	sulfuric ester hydrolase activity
IL332_01945	COG1285	pathogenesis
IL332_01965	COG4221	oxidoreductase activity
IL332_01980	COG1979	alcohol dehydrogenase
IL332_01990	COG2873	o-acetylhomoserine
IL332_02030	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IL332_02035	COG2949	membrane
IL332_02045	COG0318	PFAM AMP-dependent synthetase and ligase
IL332_02055	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IL332_02060	COG0596	Alpha beta hydrolase
IL332_02065	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IL332_02070	COG1169	isochorismate synthase
IL332_02075	COG1575	Belongs to the MenA family. Type 1 subfamily
IL332_02095	COG0513	Belongs to the DEAD box helicase family
IL332_02100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IL332_02115	COG1671	Belongs to the UPF0178 family
IL332_02140	COG3722	fumarate hydratase activity
IL332_02145	COG0246	Mannitol dehydrogenase
IL332_02155	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
IL332_02165	COG3916	Acyl-homoserine-lactone synthase
IL332_02170	COG2771	luxR family
IL332_02185	COG1560	Kdo2-lipid A biosynthetic process
IL332_02190	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IL332_02190	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IL332_02195	COG1538	Outer membrane efflux protein
IL332_02200	COG0494	nUDIX hydrolase
IL332_02205	COG3151	Protein conserved in bacteria
IL332_02215	COG3150	esterase
IL332_02220	COG1051	belongs to the nudix hydrolase family
IL332_02235	COG1566	PFAM secretion protein HlyD family protein
IL332_02240	COG1289	transmembrane transporter activity
IL332_02290	COG0484	heat shock protein binding
IL332_02300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IL332_02320	COG0204	Acyl-transferase
IL332_02325	COG1842	Phage shock protein A
IL332_02340	COG2827	Endonuclease containing a URI domain
IL332_02345	COG2962	Rard protein
IL332_02350	COG1573	uracil-dna glycosylase
IL332_02360	COG0583	DNA-binding transcription factor activity
IL332_02365	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IL332_02370	COG1121	(ABC) transporter
IL332_02375	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
IL332_02395	COG0739	heme binding
IL332_02405	COG3068	Protein conserved in bacteria
IL332_02425	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IL332_02435	COG1546	Belongs to the CinA family
IL332_02440	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IL332_02445	COG2137	regulation of response to DNA damage stimulus
IL332_02450	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IL332_02455	COG0527	aspartate kinase activity
IL332_02460	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IL332_02495	COG1686	Belongs to the peptidase S11 family
IL332_02500	COG0586	Pfam SNARE associated Golgi protein
IL332_02505	COG1253	flavin adenine dinucleotide binding
IL332_02510	COG0525	valine-tRNA ligase activity
IL332_02515	COG2927	DNA polymerase III (CHI subunit)
IL332_02520	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IL332_02530	COG0795	lipopolysaccharide-transporting ATPase activity
IL332_02550	COG0004	ammonium transporteR
IL332_02560	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IL332_02575	COG2165	general secretion pathway protein
IL332_02580	COG0084	hydrolase, TatD family'
IL332_02585	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IL332_02595	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IL332_02600	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
IL332_02605	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IL332_02615	COG4520	surface antigen
IL332_02620	COG3447	MASE1 domain protein
IL332_02620	COG5002	protein histidine kinase activity
IL332_02620	COG5001	Diguanylate cyclase
IL332_02645	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IL332_02655	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
IL332_02660	COG0776	regulation of translation
IL332_02675	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IL332_02680	COG0735	belongs to the Fur family
IL332_02705	COG0513	Belongs to the DEAD box helicase family
IL332_02710	COG3022	response to hydroperoxide
IL332_02725	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IL332_02730	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IL332_02735	COG0762	integral membrane protein
IL332_02740	COG1872	DUF167
IL332_02760	COG3112	Uncharacterised protein family (UPF0231)
IL332_02765	COG3835	regulator
IL332_02770	COG2610	gluconate transmembrane transporter activity
IL332_02775	COG1929	Belongs to the glycerate kinase type-1 family
IL332_02790	COG0583	DNA-binding transcription factor activity
IL332_02795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IL332_02810	COG0347	Belongs to the P(II) protein family
IL332_02825	COG3842	ATPase activity
IL332_02830	COG2837	iron assimilation
IL332_02835	COG1438	arginine binding
IL332_02840	COG1126	abc transporter atp-binding protein
IL332_02845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IL332_02850	COG4215	(ABC) transporter
IL332_02855	COG4160	amino acid transport
IL332_02860	COG0039	L-malate dehydrogenase activity
IL332_02865	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IL332_02870	COG1017	nitric oxide dioxygenase activity
IL332_02870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IL332_02880	COG4536	flavin adenine dinucleotide binding
IL332_02885	COG4137	Cytochrome C assembly protein
IL332_02890	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IL332_02895	COG0228	four-way junction DNA binding
IL332_02900	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IL332_02905	COG0336	Belongs to the RNA methyltransferase TrmD family
IL332_02910	COG0335	large ribosomal subunit rRNA binding
IL332_02925	COG1051	belongs to the nudix hydrolase family
IL332_02935	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IL332_02940	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IL332_02945	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IL332_02955	COG0583	DNA-binding transcription factor activity
IL332_02960	COG0640	Transcriptional regulator
IL332_02965	COG0268	Binds directly to 16S ribosomal RNA
IL332_02970	COG0728	peptidoglycan biosynthetic process
IL332_02975	COG0196	riboflavin kinase activity
IL332_02980	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IL332_02985	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IL332_02990	COG1047	Peptidyl-prolyl cis-trans
IL332_02995	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IL332_03035	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IL332_03035	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IL332_03045	COG1854	S-ribosylhomocysteine lyase activity
IL332_03050	COG3706	GGDEF domain
IL332_03055	COG0557	exoribonuclease II activity
IL332_03060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IL332_03070	COG2153	protein acetylation
IL332_03080	COG1914	H( )-stimulated, divalent metal cation uptake system
IL332_03085	COG0360	Binds together with S18 to 16S ribosomal RNA
IL332_03090	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IL332_03095	COG0359	binds to the 23S rRNA
IL332_03135	COG1238	metal cluster binding
IL332_03145	COG2918	glutathione biosynthetic process
IL332_03150	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IL332_03155	COG1027	Aspartate ammonia-lyase
IL332_03160	COG3030	protein affecting phage T7 exclusion by the F plasmid
IL332_03165	COG0534	Mate efflux family protein
IL332_03170	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IL332_03175	COG0459	protein refolding
IL332_03195	COG0564	pseudouridine synthase activity
IL332_03200	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IL332_03240	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IL332_03250	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IL332_03255	COG4208	sulfate ABC transporter
IL332_03260	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IL332_03265	COG0583	DNA-binding transcription factor activity
IL332_03270	COG3397	chitin binding
IL332_03275	COG0840	transmembrane signaling receptor activity
IL332_03300	COG1328	CTP reductase activity
IL332_03305	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IL332_03320	COG1448	Aminotransferase
IL332_03325	COG2194	sulfuric ester hydrolase activity
IL332_03345	COG1215	transferase activity, transferring glycosyl groups
IL332_03355	COG0457	Tetratricopeptide repeat
IL332_03355	COG3118	belongs to the thioredoxin family
IL332_03365	COG3118	belongs to the thioredoxin family
IL332_03365	COG0457	Tetratricopeptide repeat
IL332_03400	COG0513	Belongs to the DEAD box helicase family
IL332_03405	COG0840	transmembrane signaling receptor activity
IL332_03415	COG4166	transmembrane transport
IL332_03430	COG1024	Enoyl-CoA hydratase
IL332_03445	COG4221	oxidoreductase activity
IL332_03450	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IL332_03455	COG0442	prolyl-tRNA aminoacylation
IL332_03460	COG0840	transmembrane signaling receptor activity
IL332_03465	COG0632	four-way junction helicase activity
IL332_03470	COG2255	four-way junction helicase activity
IL332_03480	COG1271	oxidase subunit
IL332_03485	COG1294	oxidase, subunit
IL332_03490	COG4890	Cyd operon protein YbgT
IL332_03495	COG3790	cyd operon protein YbgE
IL332_03500	COG0824	Thioesterase
IL332_03505	COG0811	peptide transport
IL332_03520	COG0823	Involved in the tonB-independent uptake of proteins
IL332_03525	COG2885	chlorophyll binding
IL332_03530	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
IL332_03605	COG0840	transmembrane signaling receptor activity
IL332_03610	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IL332_03620	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IL332_03625	COG1640	4-alpha-glucanotransferase
IL332_03630	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IL332_03660	COG2130	NADP-dependent
IL332_03665	COG1846	Transcriptional regulator
IL332_03695	COG0561	phosphatase activity
IL332_03710	COG0733	neurotransmitter:sodium symporter activity
IL332_03730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IL332_03745	COG1794	racemase activity, acting on amino acids and derivatives
IL332_03755	COG1022	Amp-dependent synthetase and ligase
IL332_03765	COG0456	acetyltransferase
IL332_03785	COG5001	Diguanylate cyclase
IL332_03785	COG5002	protein histidine kinase activity
IL332_03810	COG0456	acetyltransferase
IL332_03815	COG1902	pentaerythritol trinitrate reductase activity
IL332_03830	COG2957	Belongs to the agmatine deiminase family
IL332_03835	COG0154	amidase activity
IL332_03875	COG1917	Cupin 2, conserved barrel domain protein
IL332_03875	COG2207	Transcriptional regulator
IL332_03885	COG0513	Belongs to the DEAD box helicase family
IL332_03890	COG2199	diguanylate cyclase activity
IL332_03890	COG2203	Gaf domain
IL332_03925	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
IL332_03935	COG1136	(ABC) transporter
IL332_03935	COG0577	efflux transmembrane transporter activity
IL332_03940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IL332_03945	COG0745	RESPONSE REGULATOR receiver
IL332_03955	COG2205	protein histidine kinase activity
IL332_04010	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IL332_04020	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IL332_04030	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
IL332_04035	COG1178	ABC-type Fe3 transport system permease component
IL332_04055	COG0066	3-isopropylmalate dehydratase activity
IL332_04060	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IL332_04065	COG0473	3-isopropylmalate dehydrogenase activity
IL332_04070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IL332_04080	COG0671	phosphoesterase, PA-phosphatase related
IL332_04095	COG0028	Belongs to the TPP enzyme family
IL332_04100	COG0440	acetolactate synthase activity
IL332_04105	COG0857	belongs to the CobB CobQ family
IL332_04105	COG0280	phosphate acetyltransferase
IL332_04110	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IL332_04120	COG3013	Belongs to the UPF0304 family
IL332_04125	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IL332_04130	COG2716	regulation of RNA biosynthetic process
IL332_04135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IL332_04140	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
IL332_04145	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IL332_04160	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
IL332_04180	COG5002	protein histidine kinase activity
IL332_04180	COG2198	Histidine kinase
IL332_04180	COG0784	Response regulator, receiver
IL332_04195	COG0784	Response regulator, receiver
IL332_04195	COG2205	protein histidine kinase activity
IL332_04215	COG1464	Belongs to the NlpA lipoprotein family
IL332_04220	COG2011	ABC-type metal ion transport system permease component
IL332_04225	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IL332_04250	COG0802	atpase or kinase
IL332_04260	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IL332_04265	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IL332_04270	COG1923	regulation of RNA biosynthetic process
IL332_04280	COG0330	HflC and HflK could
IL332_04285	COG0330	HflC and HflK could
IL332_04290	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
IL332_04295	COG0142	geranyltranstransferase activity
IL332_04300	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IL332_04305	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IL332_04310	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IL332_04315	COG3314	Sporulation integral membrane protein YlbJ
IL332_04320	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IL332_04325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IL332_04335	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IL332_04340	COG2967	ApaG domain
IL332_04345	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IL332_04350	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IL332_04365	COG3178	'Phosphotransferase
IL332_04370	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IL332_04375	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IL332_04380	COG2252	PERMEase
IL332_04390	COG0488	(ABC) transporter
IL332_04395	COG0741	lytic transglycosylase activity
IL332_04400	COG0463	Glycosyl transferase, family 2
IL332_04435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IL332_04445	COG3721	Heme iron utilization protein
IL332_04450	COG0748	coenzyme F420 binding
IL332_04475	COG2814	Major facilitator Superfamily
IL332_04490	COG2226	methyltransferase
IL332_04500	COG1765	OsmC-like protein
IL332_04515	COG3954	Phosphoribulokinase
IL332_04520	COG3089	Belongs to the UPF0270 family
IL332_04525	COG2203	Gaf domain
IL332_04525	COG3706	GGDEF domain
IL332_04525	COG4251	negative regulation of phosphorylation
IL332_04525	COG5001	Diguanylate cyclase
IL332_04530	COG0429	hydrolase of the alpha beta-hydrolase fold
IL332_04535	COG0784	Response regulator, receiver
IL332_04535	COG0835	chemotaxis
IL332_04545	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IL332_04550	COG1047	Peptidyl-prolyl cis-trans
IL332_04555	COG2900	Belongs to the SlyX family
IL332_04565	COG0545	Peptidyl-prolyl cis-trans isomerase
IL332_04570	COG2204	response regulator
IL332_04590	COG0737	Belongs to the 5'-nucleotidase family
IL332_04605	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IL332_04610	COG0506	proline dehydrogenase activity
IL332_04610	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IL332_04610	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IL332_04620	COG0114	fumarate hydratase activity
IL332_04630	COG1566	PFAM secretion protein HlyD family protein
IL332_04675	COG2203	Gaf domain
IL332_04675	COG2199	diguanylate cyclase activity
IL332_04675	COG2200	EAL domain
IL332_04700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IL332_04710	COG1280	lysine exporter protein (LysE YggA)
IL332_04715	COG0826	peptidase U32
IL332_04725	COG3813	Protein conserved in bacteria
IL332_04745	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IL332_04770	COG0300	oxidoreductase activity
IL332_04790	COG2610	gluconate transmembrane transporter activity
IL332_04795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IL332_04800	COG3622	Belongs to the hyi family
IL332_04805	COG0235	Class ii aldolase
IL332_04810	COG3395	kinase activity
IL332_04815	COG2084	Dehydrogenase
IL332_04820	COG1349	DNA-binding transcription factor activity
IL332_04845	COG0457	Tetratricopeptide repeat
IL332_04860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IL332_04885	COG1605	Chorismate mutase
IL332_04885	COG0077	Prephenate dehydratase
IL332_04910	COG3272	Protein of unknown function (DUF1722)
IL332_04915	COG0789	Transcriptional regulator
IL332_04920	COG0415	Belongs to the DNA photolyase family
IL332_04930	COG4221	oxidoreductase activity
IL332_04945	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IL332_04970	COG0783	Belongs to the Dps family
IL332_04975	COG1151	hydroxylamine reductase activity
IL332_04985	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IL332_05005	COG1447	Phosphotransferase system cellobiose-specific component IIA
IL332_05010	COG2723	6-phospho-beta-galactosidase activity
IL332_05020	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IL332_05025	COG5297	Belongs to the glycosyl hydrolase family 6
IL332_05025	COG2273	Hydrolase Family 16
IL332_05030	COG1472	Belongs to the glycosyl hydrolase 3 family
IL332_05045	COG2182	Extracellular solute-binding protein
IL332_05050	COG1609	Transcriptional regulator
IL332_05075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IL332_05080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IL332_05085	COG0745	RESPONSE REGULATOR receiver
IL332_05090	COG5000	phosphorelay sensor kinase activity
IL332_05090	COG5002	protein histidine kinase activity
IL332_05095	COG0659	secondary active sulfate transmembrane transporter activity
IL332_05100	COG2771	luxR family
IL332_05120	COG4104	PAAR repeat-containing protein
IL332_05175	COG1666	GTP binding
IL332_05180	COG3248	Nucleoside-binding outer membrane protein
IL332_05185	COG2211	Major facilitator Superfamily
IL332_05195	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IL332_05205	COG2813	Specifically methylates the guanine in position
IL332_05210	COG0271	Belongs to the BolA IbaG family
IL332_05215	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IL332_05220	COG1805	sodium ion transport
IL332_05225	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IL332_05230	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IL332_05235	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IL332_05240	COG2871	sodium ion transport
IL332_05245	COG1477	protein flavinylation
IL332_05260	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IL332_05265	COG0840	transmembrane signaling receptor activity
IL332_05270	COG0583	DNA-binding transcription factor activity
IL332_05285	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
IL332_05295	COG0473	3-isopropylmalate dehydrogenase activity
IL332_05300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IL332_05305	COG1611	Belongs to the LOG family
IL332_05320	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IL332_05320	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IL332_05330	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
IL332_05355	COG3098	single-species biofilm formation
IL332_05360	COG0564	pseudouridine synthase activity
IL332_05375	COG4580	involved in the transport of maltose and maltodextrins
IL332_05385	COG1263	PTS System
IL332_05385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IL332_05395	COG2171	N-acyltransferase activity
IL332_05400	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IL332_05405	COG0024	Methionine aminopeptidase
IL332_05410	COG0052	Belongs to the universal ribosomal protein uS2 family
IL332_05415	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IL332_05420	COG0528	UMP kinase activity
IL332_05425	COG0233	cytoplasmic translational termination
IL332_05430	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IL332_05435	COG0575	Belongs to the CDS family
IL332_05440	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IL332_05445	COG0750	zinc metalloprotease
IL332_05460	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IL332_05465	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IL332_05470	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IL332_05480	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IL332_05490	COG0825	malonyl-CoA metabolic process
IL332_05505	COG0814	amino acid
IL332_05510	COG0531	amino acid
IL332_05530	COG3590	peptidase
IL332_05540	COG3706	GGDEF domain
IL332_05590	COG0366	Alpha amylase catalytic
IL332_05605	COG0463	Glycosyl transferase, family 2
IL332_05620	COG2989	Protein conserved in bacteria
IL332_05625	COG3108	Peptidase M15
IL332_05635	COG2860	membrane
IL332_05645	COG1196	nuclear chromosome segregation
IL332_05650	COG3115	cell septum assembly
IL332_05655	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IL332_05665	COG1328	CTP reductase activity
IL332_05670	COG0602	queuosine metabolic process
IL332_05695	COG1566	PFAM secretion protein HlyD family protein
IL332_05705	COG3290	protein histidine kinase activity
IL332_05715	COG0697	spore germination
IL332_05735	COG3706	GGDEF domain
IL332_05740	COG0346	lactoylglutathione lyase activity
IL332_05745	COG0745	RESPONSE REGULATOR receiver
IL332_05750	COG5002	protein histidine kinase activity
IL332_05760	COG4783	chaperone-mediated protein folding
IL332_05770	COG1940	carbohydrate kinase activity
IL332_05790	COG0545	Peptidyl-prolyl cis-trans isomerase
IL332_05795	COG1131	(ABC) transporter
IL332_05800	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IL332_05810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IL332_05815	COG4597	amino acid ABC transporter
IL332_05820	COG0765	amino acid transport
IL332_05825	COG1126	abc transporter atp-binding protein
IL332_05835	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
IL332_05840	COG0678	peroxiredoxin activity
IL332_05850	COG0019	diaminopimelate decarboxylase activity
IL332_05860	COG0095	Lipoate-protein ligase
IL332_05865	COG2233	PERMEase
IL332_05885	COG2207	Transcriptional regulator
IL332_05890	COG0281	malic enzyme
IL332_05920	COG0733	neurotransmitter:sodium symporter activity
IL332_05925	COG1752	Esterase of the alpha-beta hydrolase superfamily
IL332_05930	COG3706	GGDEF domain
IL332_05940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IL332_05945	COG1032	radical SAM domain protein
IL332_05975	COG0673	inositol 2-dehydrogenase activity
IL332_05980	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IL332_05995	COG0741	lytic transglycosylase activity
IL332_05995	COG1196	nuclear chromosome segregation
IL332_05995	COG0739	heme binding
IL332_06020	COG0788	formyltetrahydrofolate deformylase activity
IL332_06025	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IL332_06045	COG0791	NLP P60 protein
IL332_06050	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
IL332_06075	COG0784	Response regulator, receiver
IL332_06075	COG2205	protein histidine kinase activity
IL332_06100	COG2205	protein histidine kinase activity
IL332_06100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IL332_06105	COG3384	dioxygenase
IL332_06115	COG1283	sodium-dependent phosphate transmembrane transporter activity
IL332_06125	COG0531	amino acid
IL332_06130	COG0531	amino acid
IL332_06145	COG1012	belongs to the aldehyde dehydrogenase family
IL332_06150	COG1917	Cupin 2, conserved barrel domain protein
IL332_06150	COG1396	sequence-specific DNA binding
IL332_06155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IL332_06190	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IL332_06190	COG4651	solute:proton antiporter activity
IL332_06205	COG2974	May be involved in recombination
IL332_06210	COG1247	-acetyltransferase
IL332_06215	COG0420	3'-5' exonuclease activity
IL332_06225	COG3038	cytochrome b561
IL332_06230	COG2190	(PTS) system
IL332_06240	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IL332_06245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IL332_06250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IL332_06265	COG1720	tRNA m6t6A37 methyltransferase activity
IL332_06285	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IL332_06290	COG4988	ABC transporter
IL332_06305	COG0745	RESPONSE REGULATOR receiver
IL332_06315	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IL332_06330	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
IL332_06335	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
IL332_06345	COG0083	homoserine kinase activity
IL332_06350	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IL332_06365	COG2801	Transposase and inactivated derivatives
IL332_06380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IL332_06390	COG3220	belongs to the UPF0276 family
IL332_06420	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IL332_06425	COG1289	transmembrane transporter activity
IL332_06430	COG1763	Mo-molybdopterin cofactor biosynthetic process
IL332_06435	COG0746	molybdenum cofactor guanylyltransferase activity
IL332_06470	COG3264	Mechanosensitive ion channel
IL332_06470	COG1196	nuclear chromosome segregation
IL332_06480	COG2850	peptidyl-arginine hydroxylation
IL332_06485	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IL332_06490	COG2915	High frequency lysogenization protein hflD homolog
IL332_06495	COG0482	sulfurtransferase activity
IL332_06505	COG1187	pseudouridine synthase activity
IL332_06510	COG0456	acetyltransferase
IL332_06545	COG0538	isocitrate dehydrogenase activity
IL332_06555	COG3048	D-serine ammonia-lyase activity
IL332_06560	COG0583	DNA-binding transcription factor activity
IL332_06565	COG2916	Histone family protein nucleoid-structuring protein H-NS
IL332_06570	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IL332_06575	COG2375	cellular response to nickel ion
IL332_06580	COG1538	Outer membrane efflux protein
IL332_06585	COG1136	(ABC) transporter
IL332_06585	COG0577	efflux transmembrane transporter activity
IL332_06590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IL332_06600	COG0497	DNA recombination
IL332_06605	COG3706	GGDEF domain
IL332_06610	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IL332_06615	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IL332_06620	COG0443	Heat shock 70 kDa protein
IL332_06625	COG0484	heat shock protein binding
IL332_06655	COG1285	pathogenesis
IL332_06665	COG0446	pyridine nucleotide-disulphide oxidoreductase
IL332_06685	COG2391	methyltransferase activity
IL332_06725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IL332_06735	COG0708	Exodeoxyribonuclease III
IL332_06745	COG0745	RESPONSE REGULATOR receiver
IL332_06760	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
IL332_06770	COG1846	Transcriptional regulator
IL332_06795	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IL332_06800	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IL332_06810	COG1845	cytochrome c oxidase, subunit III
IL332_06815	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IL332_06820	COG0109	protoheme IX farnesyltransferase activity
IL332_06835	COG5507	3-demethylubiquinone-9 3-methyltransferase
IL332_06840	COG2175	clavaminate synthase activity
IL332_06845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IL332_06850	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IL332_06855	COG4521	taurine ABC transporter
IL332_06890	COG2801	Transposase and inactivated derivatives
IL332_06910	COG0133	tryptophan synthase activity
IL332_06915	COG0134	indole-3-glycerol-phosphate synthase activity
IL332_06915	COG0135	phosphoribosylanthranilate isomerase activity
IL332_06920	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IL332_06925	COG0512	Glutamine amidotransferase of anthranilate synthase
IL332_06925	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IL332_06930	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IL332_06935	COG0613	PHP domain protein
IL332_06940	COG0009	L-threonylcarbamoyladenylate synthase
IL332_06950	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IL332_06975	COG1309	transcriptional regulator
IL332_06980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IL332_06985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IL332_07040	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IL332_07050	COG1960	acyl-CoA dehydrogenase activity
IL332_07055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IL332_07065	COG0469	pyruvate kinase activity
IL332_07070	COG1737	Transcriptional regulator
IL332_07095	COG1091	dTDP-4-dehydrorhamnose reductase activity
IL332_07125	COG1181	Belongs to the D-alanine--D-alanine ligase family
IL332_07155	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IL332_07165	COG2801	Transposase and inactivated derivatives
IL332_07185	COG3132	Protein of unknown function, DUF480
IL332_07225	COG1278	Cold shock
IL332_07250	COG4166	transmembrane transport
IL332_07265	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IL332_07280	COG4166	transmembrane transport
IL332_07300	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
IL332_07305	COG0835	chemotaxis
IL332_07305	COG0784	Response regulator, receiver
IL332_07310	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IL332_07315	COG1815	bacterial-type flagellum-dependent cell motility
IL332_07330	COG1749	Flagellar hook protein flgE
IL332_07335	COG4786	Flagellar basal body rod
IL332_07350	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
IL332_07360	COG1705	Flagellar rod assembly protein muramidase FlgJ
IL332_07360	COG3951	Flagellar rod assembly protein muramidase FlgJ
IL332_07375	COG2239	Acts as a magnesium transporter
IL332_07385	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IL332_07390	COG2716	regulation of RNA biosynthetic process
IL332_07415	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IL332_07420	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IL332_07425	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IL332_07430	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IL332_07450	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IL332_07465	COG0590	tRNA wobble adenosine to inosine editing
IL332_07470	COG0573	inorganic phosphate transmembrane transporter activity
IL332_07475	COG0581	inorganic phosphate transmembrane transporter activity
IL332_07480	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IL332_07485	COG0704	Plays a role in the regulation of phosphate uptake
IL332_07490	COG1253	flavin adenine dinucleotide binding
IL332_07505	COG0531	amino acid
IL332_07515	COG1126	abc transporter atp-binding protein
IL332_07520	COG0765	amino acid transport
IL332_07525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IL332_07530	COG3706	GGDEF domain
IL332_07535	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IL332_07555	COG1785	Belongs to the alkaline phosphatase family
IL332_07560	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IL332_07565	COG0477	Major facilitator Superfamily
IL332_07570	COG0123	including yeast histone deacetylase and acetoin utilization protein
IL332_07580	COG1199	ATP-dependent helicase activity
IL332_07595	COG1448	Aminotransferase
IL332_07600	COG0433	COG0433 Predicted ATPase
IL332_07615	COG2333	competence protein COMEC
IL332_07615	COG0658	competence protein
IL332_07620	COG1132	(ABC) transporter
IL332_07630	COG2835	tetraacyldisaccharide 4'-kinase activity
IL332_07635	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IL332_07640	COG2197	response regulator
IL332_07645	COG0322	excinuclease ABC activity
IL332_07745	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
IL332_07750	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IL332_07755	COG1328	CTP reductase activity
IL332_07880	COG0582	viral genome integration into host DNA
IL332_07895	COG0604	alcohol dehydrogenase
IL332_07900	COG1309	transcriptional regulator
IL332_07905	COG2261	transglycosylase associated protein
IL332_07910	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IL332_07920	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IL332_07990	COG0023	Translation Initiation Factor
IL332_08035	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IL332_08040	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IL332_08045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IL332_08050	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IL332_08055	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IL332_08065	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IL332_08070	COG0505	Belongs to the CarA family
IL332_08075	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IL332_08080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IL332_08085	COG3706	GGDEF domain
IL332_08110	COG0513	Belongs to the DEAD box helicase family
IL332_08120	COG4104	PAAR repeat-containing protein
IL332_08145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IL332_08150	COG0765	amino acid transport
IL332_08155	COG1126	abc transporter atp-binding protein
IL332_08160	COG0493	'glutamate synthase
IL332_08165	COG0070	glutamate synthase
IL332_08165	COG0069	glutamate synthase activity
IL332_08165	COG0067	glutamate synthase
IL332_08170	COG1242	4 iron, 4 sulfur cluster binding
IL332_08245	COG1113	amino acid transport
IL332_08255	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IL332_08300	COG1464	Belongs to the NlpA lipoprotein family
IL332_08305	COG0671	phosphoesterase, PA-phosphatase related
IL332_08310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IL332_08315	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IL332_08325	COG0101	tRNA pseudouridine synthase activity
IL332_08330	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IL332_08340	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
IL332_08345	COG2920	part of a sulfur-relay system
IL332_08350	COG1289	transmembrane transporter activity
IL332_08355	COG0670	Belongs to the BI1 family
IL332_08390	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IL332_08400	COG5001	Diguanylate cyclase
IL332_08405	COG0564	pseudouridine synthase activity
IL332_08420	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
IL332_08430	COG0625	glutathione transferase activity
IL332_08445	COG0367	asparagine synthase
IL332_08455	COG0647	UMP catabolic process
IL332_08460	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IL332_08470	COG1902	pentaerythritol trinitrate reductase activity
IL332_08475	COG1253	flavin adenine dinucleotide binding
IL332_08490	COG0247	lactate metabolic process
IL332_08490	COG0277	FAD linked oxidase domain protein
IL332_08500	COG2050	protein possibly involved in aromatic compounds catabolism
IL332_08515	COG5001	Diguanylate cyclase
IL332_08520	COG0583	DNA-binding transcription factor activity
IL332_08525	COG2814	Major facilitator Superfamily
IL332_08530	COG2056	Na+-H+ antiporter family
IL332_08535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IL332_08550	COG0483	inositol monophosphate 1-phosphatase activity
IL332_08560	COG0625	glutathione transferase activity
IL332_08565	COG0625	glutathione transferase activity
IL332_08575	COG0601	transmembrane transport
IL332_08580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IL332_08585	COG0444	Belongs to the ABC transporter superfamily
IL332_08610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IL332_08615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IL332_08620	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IL332_08625	COG0509	glycine decarboxylation via glycine cleavage system
IL332_08630	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IL332_08630	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IL332_08645	COG3318	Belongs to the UPF0149 family
IL332_08645	COG3012	SEC-C Motif Domain Protein
IL332_08650	COG0714	Associated with various cellular activities
IL332_08660	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IL332_08710	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IL332_08755	COG3634	alkyl hydroperoxide reductase activity
IL332_08760	COG0450	alkyl hydroperoxide reductase
IL332_08765	COG0517	IMP dehydrogenase activity
IL332_08770	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IL332_08775	COG0343	queuine tRNA-ribosyltransferase activity
IL332_08780	COG1862	Preprotein translocase
IL332_08785	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IL332_08795	COG2897	thiosulfate sulfurtransferase activity
IL332_08805	COG0826	peptidase U32
IL332_08810	COG0826	peptidase U32
IL332_08815	COG3154	lipid carrier protein
IL332_08830	COG1104	cysteine desulfurase activity
IL332_08835	COG0822	iron-sulfur transferase activity
IL332_08845	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IL332_08850	COG0443	Heat shock 70 kDa protein
IL332_08855	COG0633	Ferredoxin
IL332_08870	COG0105	UTP biosynthetic process
IL332_08875	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IL332_08885	COG1426	Protein conserved in bacteria
IL332_08895	COG0124	histidyl-tRNA synthetase
IL332_08900	COG2976	Protein conserved in bacteria
IL332_08905	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IL332_08910	COG1160	GTP binding
IL332_08915	COG1645	bacterial-type flagellum-dependent swarming motility
IL332_08920	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IL332_08930	COG1007	ATP synthesis coupled electron transport
IL332_08935	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IL332_08945	COG0713	ATP synthesis coupled electron transport
IL332_08950	COG0839	Belongs to the complex I subunit 6 family
IL332_08955	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IL332_08960	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IL332_08965	COG1034	ATP synthesis coupled electron transport
IL332_08980	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IL332_08980	COG0649	NAD binding
IL332_08985	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IL332_08990	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IL332_08995	COG1360	Flagellar Motor Protein
IL332_09020	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IL332_09040	COG0724	RNA recognition motif
IL332_09045	COG4989	oxidoreductase activity
IL332_09070	COG0745	RESPONSE REGULATOR receiver
IL332_09075	COG0583	DNA-binding transcription factor activity
IL332_09085	COG3300	MHYT domain
IL332_09085	COG5001	Diguanylate cyclase
IL332_09090	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IL332_09120	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IL332_09125	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IL332_09130	COG0539	negative regulation of cytoplasmic translation
IL332_09135	COG0776	regulation of translation
IL332_09145	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IL332_09165	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IL332_09170	COG0602	queuosine metabolic process
IL332_09175	COG3530	Putative quorum-sensing-regulated virulence factor
IL332_09180	COG2096	Adenosyltransferase
IL332_09185	COG2916	Histone family protein nucleoid-structuring protein H-NS
IL332_09190	COG1757	Na H antiporter
IL332_09195	COG1435	thymidine kinase activity
IL332_09215	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IL332_09230	COG1349	DNA-binding transcription factor activity
IL332_09235	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
IL332_09255	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IL332_09260	COG0626	cystathionine gamma-synthase activity
IL332_09270	COG2910	NAD(P)H-binding
IL332_09275	COG0583	DNA-binding transcription factor activity
IL332_09280	COG4977	sequence-specific DNA binding
IL332_09280	COG1917	Cupin 2, conserved barrel domain protein
IL332_09285	COG2200	EAL domain
IL332_09290	COG2203	Gaf domain
IL332_09290	COG2199	diguanylate cyclase activity
IL332_09300	COG4774	siderophore transport
IL332_09310	COG0583	DNA-binding transcription factor activity
IL332_09315	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IL332_09325	COG0617	tRNA 3'-terminal CCA addition
IL332_09325	COG0517	IMP dehydrogenase activity
IL332_09325	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IL332_09330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IL332_09335	COG3046	protein related to deoxyribodipyrimidine photolyase
IL332_09350	COG4235	cytochrome complex assembly
IL332_09350	COG3088	subunit of a heme lyase
IL332_09355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IL332_09365	COG3301	Polysulphide reductase, NrfD
IL332_09370	COG0437	4 iron, 4 sulfur cluster binding
IL332_09375	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
IL332_09400	COG0247	lactate metabolic process
IL332_09410	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
IL332_09415	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IL332_09420	COG3012	SEC-C Motif Domain Protein
IL332_09425	COG0840	transmembrane signaling receptor activity
IL332_09430	COG1846	Transcriptional regulator
IL332_09430	COG1940	carbohydrate kinase activity
IL332_09435	COG3290	protein histidine kinase activity
IL332_09440	COG4565	transcriptional regulatory protein
IL332_09460	COG0741	lytic transglycosylase activity
IL332_09460	COG0739	heme binding
IL332_09460	COG1196	nuclear chromosome segregation
IL332_09465	COG2985	domain, Protein
IL332_09465	COG0569	domain protein
IL332_09475	COG0556	nucleotide-excision repair
IL332_09485	COG0586	Pfam SNARE associated Golgi protein
IL332_09490	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IL332_09495	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IL332_09500	COG2186	Transcriptional regulator
IL332_09505	COG2719	SpoVR family
IL332_09510	COG2718	Belongs to the UPF0229 family
IL332_09515	COG2766	serine protein kinase
IL332_09520	COG0514	ATP-dependent DNA helicase (RecQ)
IL332_09525	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IL332_09530	COG0814	amino acid
IL332_09565	COG0058	SHG alpha-glucan phosphorylase activity
IL332_09575	COG0471	metal ion transport
IL332_09590	COG1132	(ABC) transporter
IL332_09595	COG1132	(ABC) transporter
IL332_09620	COG2501	S4 domain
IL332_09630	COG3243	poly(R)-hydroxyalkanoic acid synthase
IL332_09650	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
IL332_09655	COG2329	Antibiotic biosynthesis monooxygenase
IL332_09680	COG1742	UPF0060 membrane protein
IL332_09695	COG0513	Belongs to the DEAD box helicase family
IL332_09710	COG1181	Belongs to the D-alanine--D-alanine ligase family
IL332_09715	COG3148	PFAM DTW domain containing protein
IL332_09725	COG0730	response to heat
IL332_09730	COG0583	DNA-binding transcription factor activity
IL332_09785	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IL332_09790	COG1011	Hydrolase
IL332_09795	COG1473	amidohydrolase
IL332_09800	COG0205	6-phosphofructokinase activity
IL332_09810	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IL332_09815	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IL332_09825	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
IL332_09830	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
IL332_09845	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IL332_09870	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IL332_09875	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IL332_09910	COG2824	Alkylphosphonate utilization operon protein PhnA
IL332_09945	COG2840	Smr protein MutS2
IL332_09950	COG2890	protein-(glutamine-N5) methyltransferase activity
IL332_09955	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IL332_09965	COG0513	Belongs to the DEAD box helicase family
IL332_09970	COG5654	RES domain protein
IL332_09980	COG0814	amino acid
IL332_09985	COG1609	Transcriptional regulator
IL332_09990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IL332_09990	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IL332_09995	COG1105	Belongs to the carbohydrate kinase PfkB family
IL332_10000	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IL332_10000	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IL332_10000	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IL332_10005	COG3313	Fe-S protein
IL332_10010	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IL332_10015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IL332_10020	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IL332_10025	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IL332_10035	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IL332_10065	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IL332_10070	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IL332_10075	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IL332_10080	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IL332_10085	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IL332_10090	COG0072	phenylalanine-tRNA ligase activity
IL332_10090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IL332_10095	COG0776	regulation of translation
IL332_10130	COG1609	Transcriptional regulator
IL332_10135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IL332_10140	COG1879	ABC-type sugar transport system periplasmic component
IL332_10145	COG1172	Belongs to the binding-protein-dependent transport system permease family
IL332_10150	COG1129	ABC transporter
IL332_10155	COG1869	D-ribose catabolic process
IL332_10160	COG0625	glutathione transferase activity
IL332_10175	COG0037	tRNA processing
IL332_10180	COG0589	response to stress
IL332_10185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IL332_10210	COG2010	Cytochrome c
IL332_10225	COG3278	Belongs to the heme-copper respiratory oxidase family
IL332_10235	COG1956	GAF domain-containing protein
IL332_10240	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
IL332_10250	COG0308	aminopeptidase N
IL332_10260	COG2902	Dehydrogenase
IL332_10265	COG0167	dihydroorotate dehydrogenase activity
IL332_10275	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IL332_10275	COG0116	Belongs to the methyltransferase superfamily
IL332_10285	COG0488	(ABC) transporter
IL332_10300	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IL332_10305	COG1067	ATP-dependent peptidase activity
IL332_10315	COG3141	response to X-ray
IL332_10325	COG2995	paraquat-inducible protein a
IL332_10330	COG3008	intermembrane lipid transfer
IL332_10335	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
IL332_10335	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IL332_10350	COG0084	hydrolase, TatD family'
IL332_10355	COG0470	DNA polymerase III
IL332_10360	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IL332_10365	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IL332_10370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IL332_10375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IL332_10380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IL332_10385	COG1028	Short-chain dehydrogenase reductase Sdr
IL332_10395	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IL332_10400	COG0416	fatty acid biosynthetic process
IL332_10405	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IL332_10410	COG1399	metal-binding, possibly nucleic acid-binding protein
IL332_10425	COG0564	pseudouridine synthase activity
IL332_10430	COG1530	ribonuclease E activity
IL332_10435	COG0306	phosphate transporter
IL332_10440	COG0717	Belongs to the dCTP deaminase family
IL332_10445	COG0572	uridine kinase
IL332_10450	COG0489	protein tyrosine kinase activity
IL332_10455	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IL332_10455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IL332_10460	COG0625	glutathione transferase activity
IL332_10465	COG1254	Belongs to the acylphosphatase family
IL332_10470	COG0840	transmembrane signaling receptor activity
IL332_10475	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IL332_10500	COG0709	Synthesizes selenophosphate from selenide and ATP
IL332_10505	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
IL332_10510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IL332_10515	COG3437	response regulator, receiver
IL332_10525	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IL332_10535	COG1643	Atp-dependent helicase
IL332_10545	COG2197	response regulator
IL332_10550	COG3314	Sporulation integral membrane protein YlbJ
IL332_10560	COG0583	DNA-binding transcription factor activity
IL332_10565	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IL332_10580	COG2832	Protein of unknown function (DUF454)
IL332_10585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IL332_10595	COG0697	spore germination
IL332_10610	COG0318	PFAM AMP-dependent synthetase and ligase
IL332_10615	COG0596	Alpha beta hydrolase
IL332_10625	COG1214	PFAM Peptidase M22, glycoprotease
IL332_10630	COG1199	ATP-dependent helicase activity
IL332_10640	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IL332_10645	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IL332_10650	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IL332_10655	COG0131	Imidazoleglycerol-phosphate dehydratase
IL332_10655	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IL332_10660	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IL332_10665	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IL332_10680	COG2198	Histidine kinase
IL332_10680	COG0784	Response regulator, receiver
IL332_10680	COG2205	protein histidine kinase activity
IL332_10685	COG0107	imidazoleglycerol-phosphate synthase activity
IL332_10690	COG0140	phosphoribosyl-ATP diphosphatase activity
IL332_10690	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IL332_10700	COG2378	regulation of single-species biofilm formation
IL332_10705	COG0318	PFAM AMP-dependent synthetase and ligase
IL332_10710	COG3134	Outer membrane lipoprotein
IL332_10725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IL332_10745	COG4681	YaeQ
IL332_10755	COG1250	3-hydroxyacyl-CoA dehydrogenase
IL332_10755	COG1024	Enoyl-CoA hydratase
IL332_10760	COG0183	Belongs to the thiolase family
IL332_10765	COG0714	Associated with various cellular activities
IL332_10795	COG1595	DNA-templated transcription, initiation
IL332_10805	COG2067	long-chain fatty acid transport protein
IL332_10810	COG2067	long-chain fatty acid transport protein
IL332_10815	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IL332_10835	COG3123	guanosine phosphorylase activity
IL332_10840	COG1760	l-serine dehydratase
IL332_10845	COG1760	l-serine dehydratase
IL332_10850	COG2951	lytic endotransglycosylase activity
IL332_10855	COG3100	YcgL domain-containing protein
IL332_10860	COG0850	regulation of cytokinetic process
IL332_10865	COG2894	cell division
IL332_10870	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
IL332_10875	COG3099	Belongs to the UPF0263 family
IL332_10880	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IL332_10895	COG2996	Protein conserved in bacteria
IL332_10920	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IL332_10925	COG0697	spore germination
IL332_10930	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IL332_10935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IL332_10950	COG0307	riboflavin synthase, alpha
IL332_10960	COG0534	Mate efflux family protein
IL332_10990	COG0417	DNA replication proofreading
IL332_11005	COG1560	Kdo2-lipid A biosynthetic process
IL332_11010	COG1560	Kdo2-lipid A biosynthetic process
IL332_11020	COG0583	DNA-binding transcription factor activity
IL332_11025	COG0673	inositol 2-dehydrogenase activity
IL332_11030	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IL332_11055	COG2723	6-phospho-beta-galactosidase activity
IL332_11060	COG0583	DNA-binding transcription factor activity
IL332_11070	COG0243	molybdopterin cofactor binding
IL332_11075	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IL332_11090	COG0583	DNA-binding transcription factor activity
IL332_11095	COG1879	ABC-type sugar transport system periplasmic component
IL332_11100	COG1129	ABC transporter
IL332_11105	COG1172	Belongs to the binding-protein-dependent transport system permease family
IL332_11120	COG3039	Transposase
IL332_11130	COG0730	response to heat
IL332_11140	COG1028	Short-chain dehydrogenase reductase Sdr
IL332_11150	COG1024	Enoyl-CoA hydratase
IL332_11155	COG1024	Enoyl-CoA hydratase
IL332_11160	COG1960	acyl-CoA dehydrogenase activity
IL332_11170	COG1960	acyl-CoA dehydrogenase activity
IL332_11175	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IL332_11180	COG1024	Enoyl-CoA hydratase
IL332_11205	COG1584	GPR1 FUN34 yaaH family protein
IL332_11210	COG3228	Belongs to the MtfA family
IL332_11220	COG1115	amino acid carrier protein
IL332_11225	COG1024	Enoyl-CoA hydratase
IL332_11240	COG3162	membrane
IL332_11245	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IL332_11250	COG0488	(ABC) transporter
IL332_11255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IL332_11260	COG0776	regulation of translation
IL332_11265	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IL332_11270	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IL332_11275	COG0740	serine-type endopeptidase activity
IL332_11280	COG0544	peptidyl-prolyl cis-trans isomerase activity
IL332_11290	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
IL332_11295	COG4591	ABC-type transport system involved in lipoprotein release permease component
IL332_11300	COG1136	(ABC) transporter
IL332_11315	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IL332_11320	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
IL332_11335	COG0697	spore germination
IL332_11345	COG2062	phosphohistidine phosphatase, SixA
IL332_11355	COG0500	methyltransferase
IL332_11395	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IL332_11395	COG0519	Catalyzes the synthesis of GMP from XMP
IL332_11400	COG0517	IMP dehydrogenase activity
IL332_11400	COG0516	GMP reductase activity
IL332_11435	COG1570	exodeoxyribonuclease VII activity
IL332_11445	COG2885	chlorophyll binding
IL332_11465	COG2154	pterin-4-alpha-carbinolamine dehydratase
IL332_11475	COG3768	UPF0283 membrane protein
IL332_11480	COG3106	COG3106 Predicted ATPase
IL332_11495	COG1842	Phage shock protein A
IL332_11500	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IL332_11515	COG4171	peptide transport system, permease
IL332_11525	COG4172	Belongs to the ABC transporter superfamily
IL332_11535	COG1609	Transcriptional regulator
IL332_11545	COG2723	6-phospho-beta-galactosidase activity
IL332_11550	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IL332_11555	COG1286	toxin biosynthetic process
IL332_11560	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IL332_11565	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IL332_11570	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IL332_11575	COG1674	ftsk spoiiie
IL332_11575	COG0531	amino acid
IL332_11585	COG0686	Belongs to the AlaDH PNT family
IL332_11590	COG0492	ferredoxin-NADP+ reductase activity
IL332_11595	COG3706	GGDEF domain
IL332_11600	COG3134	Outer membrane lipoprotein
IL332_11605	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IL332_11615	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IL332_11620	COG0542	response to heat
IL332_11625	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IL332_11630	COG1278	Cold shock
IL332_11635	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IL332_11650	COG1944	ATP diphosphatase activity
IL332_11655	COG2116	formate transmembrane transporter activity
IL332_11660	COG1882	Formate acetyltransferase
IL332_11665	COG2983	Belongs to the UPF0260 family
IL332_11680	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IL332_11685	COG0045	succinate-CoA ligase (ADP-forming) activity
IL332_11690	COG0508	dehydrogenase complex catalyzes the overall conversion of
IL332_11695	COG0567	Dehydrogenase, E1 component
IL332_11710	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IL332_11715	COG2009	succinate dehydrogenase
IL332_11735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IL332_11750	COG3069	C4-dicarboxylate transmembrane transporter activity
IL332_11765	COG1451	nucleotide metabolic process
IL332_11780	COG0254	rRNA binding
IL332_11785	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IL332_11795	COG1172	Belongs to the binding-protein-dependent transport system permease family
IL332_11800	COG1129	ABC transporter
IL332_11805	COG1879	ABC-type sugar transport system periplasmic component
IL332_11810	COG1069	ribulokinase activity
IL332_11825	COG0583	DNA-binding transcription factor activity
IL332_11830	COG0436	Aminotransferase
IL332_11835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IL332_11910	COG1263	PTS System
IL332_11910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IL332_11915	COG1874	Beta-galactosidase
IL332_11920	COG3867	Arabinogalactan endo-beta-1,4-galactanase
IL332_11925	COG3833	ABC-type maltose transport systems, permease component
IL332_11930	COG1175	transmembrane transport
IL332_11935	COG2182	Extracellular solute-binding protein
IL332_11960	COG4580	involved in the transport of maltose and maltodextrins
IL332_11965	COG1609	Transcriptional regulator
IL332_11970	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IL332_11975	COG1085	galactose-1-phosphate uridylyltransferase
IL332_12000	COG0300	oxidoreductase activity
IL332_12035	COG2925	Exonuclease
IL332_12045	COG3345	alpha-galactosidase
IL332_12050	COG1380	Effector of murein hydrolase LrgA
IL332_12055	COG1346	cytolysis
IL332_12060	COG0295	cytidine deaminase activity
IL332_12065	COG1022	Amp-dependent synthetase and ligase
IL332_12080	COG0861	Integral membrane protein TerC family
IL332_12085	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IL332_12090	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IL332_12095	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IL332_12140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IL332_12145	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IL332_12150	COG1120	ATPase activity
IL332_12165	COG3321	synthase
IL332_12165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IL332_12165	COG1028	Short-chain dehydrogenase reductase Sdr
IL332_12165	COG0318	PFAM AMP-dependent synthetase and ligase
IL332_12165	COG0300	oxidoreductase activity
IL332_12175	COG1028	Short-chain dehydrogenase reductase Sdr
IL332_12185	COG3433	isochorismatase activity
IL332_12185	COG1535	isochorismatase
IL332_12190	COG1021	2,3-dihydroxybenzoate-AMP ligase
IL332_12215	COG3300	MHYT domain
IL332_12215	COG5001	Diguanylate cyclase
IL332_12230	COG0840	transmembrane signaling receptor activity
IL332_12235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IL332_12240	COG3788	relative of glutathione S-transferase, MAPEG superfamily
IL332_12245	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IL332_12250	COG0563	adenylate kinase activity
IL332_12255	COG0326	Molecular chaperone. Has ATPase activity
IL332_12260	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IL332_12270	COG3158	transport of potassium into the cell
IL332_12275	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
IL332_12280	COG0298	carbon dioxide binding
IL332_12290	COG0309	Hydrogenase expression formation protein (HypE)
IL332_12295	COG0375	protein maturation
IL332_12300	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IL332_12305	COG1124	(ABC) transporter
IL332_12315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IL332_12330	COG1773	rubredoxin
IL332_12335	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IL332_12340	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
IL332_12345	COG5557	Pfam Polysulphide reductase, NrfD
IL332_12350	COG0437	4 iron, 4 sulfur cluster binding
IL332_12355	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
IL332_12400	COG3829	transcription factor binding
IL332_12465	COG3415	Transposase
IL332_12465	COG2801	Transposase and inactivated derivatives
IL332_12475	COG3209	COG3209 Rhs family protein
IL332_12485	COG3501	Rhs element vgr protein
IL332_12530	COG2308	Evidence 4 Homologs of previously reported genes of
IL332_12565	COG0672	)-iron permease
IL332_12615	COG0577	efflux transmembrane transporter activity
IL332_12635	COG3039	Transposase
IL332_12655	COG1139	Iron-sulfur cluster binding protein
IL332_12660	COG0247	lactate metabolic process
IL332_12670	COG0583	DNA-binding transcription factor activity
IL332_12700	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IL332_12700	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IL332_12705	COG0527	aspartate kinase activity
IL332_12720	COG0393	Putative heavy-metal-binding
IL332_12730	COG1252	NADH dehydrogenase
IL332_12735	COG3150	esterase
IL332_12740	COG1164	Oligoendopeptidase f
IL332_12765	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IL332_12770	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IL332_12805	COG0537	adenosine 5'-monophosphoramidase activity
IL332_12820	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IL332_12840	COG1301	dicarboxylic acid transport
IL332_12850	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IL332_12855	COG0861	Integral membrane protein TerC family
IL332_12870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IL332_12875	COG0601	transmembrane transport
IL332_12885	COG2095	MarC family integral membrane protein
IL332_12890	COG1012	belongs to the aldehyde dehydrogenase family
IL332_12890	COG1454	alcohol dehydrogenase
IL332_12905	COG3279	Response regulator of the LytR AlgR family
IL332_12910	COG1966	Carbon starvation protein
IL332_12925	COG1566	PFAM secretion protein HlyD family protein
IL332_12930	COG1061	Type III restriction enzyme res subunit
IL332_12935	COG2027	D-alanyl-D-alanine carboxypeptidase
IL332_12940	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IL332_12950	COG0436	Aminotransferase
IL332_12955	COG1288	antiporter activity
IL332_12960	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IL332_12980	COG0697	spore germination
IL332_12985	COG4657	Part of a membrane complex involved in electron transport
IL332_12990	COG2878	Part of a membrane complex involved in electron transport
IL332_13000	COG4658	electron transport chain
IL332_13005	COG4659	FMN binding
IL332_13010	COG4660	Part of a membrane complex involved in electron transport
IL332_13015	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IL332_13020	COG0346	lactoylglutathione lyase activity
IL332_13040	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IL332_13050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IL332_13055	COG1086	Polysaccharide biosynthesis protein
IL332_13060	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IL332_13065	COG2226	methyltransferase
IL332_13095	COG1216	Glycosyl transferase, family 2
IL332_13105	COG0562	UDP-galactopyranose mutase
IL332_13110	COG1215	transferase activity, transferring glycosyl groups
IL332_13125	COG0318	PFAM AMP-dependent synthetase and ligase
IL332_13130	COG1028	Short-chain dehydrogenase reductase Sdr
IL332_13145	COG1083	cytidylyl-transferase
IL332_13155	COG2089	acid synthase
IL332_13215	COG0301	tRNA thio-modification
IL332_13215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IL332_13225	COG4953	penicillin-binding protein 1C
IL332_13230	COG2373	Large extracellular alpha-helical protein
IL332_13235	COG0628	permease
IL332_13260	COG0446	pyridine nucleotide-disulphide oxidoreductase
IL332_13270	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IL332_13280	COG4160	amino acid transport
IL332_13290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IL332_13300	COG2431	L-lysine efflux transmembrane transporter activity
IL332_13305	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IL332_13310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IL332_13335	COG1393	Belongs to the ArsC family
IL332_13345	COG4783	chaperone-mediated protein folding
IL332_13350	COG0425	Belongs to the sulfur carrier protein TusA family
IL332_13375	COG3842	ATPase activity
IL332_13380	COG3833	ABC-type maltose transport systems, permease component
IL332_13385	COG1175	transmembrane transport
IL332_13395	COG3081	Nucleoid-associated protein
IL332_13400	COG3082	Protein of unknown function (DUF1414)
IL332_13405	COG3083	sulfuric ester hydrolase activity
IL332_13415	COG1770	oligopeptidase
IL332_13435	COG4574	serine-type endopeptidase inhibitor activity
IL332_13440	COG3085	chromosome segregation
IL332_13450	COG1605	Chorismate mutase
IL332_13450	COG0287	Prephenate dehydrogenase
IL332_13455	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IL332_13460	COG0584	glycerophosphoryl diester phosphodiesterase
IL332_13470	COG1349	DNA-binding transcription factor activity
IL332_13475	COG2271	Major facilitator Superfamily
IL332_13480	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IL332_13485	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IL332_13490	COG0583	DNA-binding transcription factor activity
IL332_13510	COG0656	L-ascorbic acid biosynthetic process
IL332_13515	COG2814	Major facilitator Superfamily
IL332_13525	COG1294	oxidase, subunit
IL332_13530	COG1271	oxidase subunit
IL332_13535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IL332_13545	COG2979	Protein of unknown function (DUF533)
IL332_13565	COG0583	DNA-binding transcription factor activity
IL332_13575	COG2807	transmembrane transport
IL332_13585	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IL332_13600	COG2801	Transposase and inactivated derivatives
IL332_13625	COG1166	arginine decarboxylase activity
IL332_13630	COG2195	Cleaves the N-terminal amino acid of tripeptides
IL332_13645	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IL332_13660	COG0583	DNA-binding transcription factor activity
IL332_13675	COG0840	transmembrane signaling receptor activity
IL332_13680	COG0302	gtp cyclohydrolase
IL332_13690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IL332_13705	COG2267	carboxylic ester hydrolase activity
IL332_13725	COG0314	molybdopterin synthase activity
IL332_13730	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IL332_13735	COG0315	cyclic pyranopterin monophosphate synthase activity
IL332_13740	COG0521	Mo-molybdopterin cofactor biosynthetic process
IL332_13745	COG3005	denitrification pathway
IL332_13755	COG0348	domain, Protein
IL332_13760	COG0437	4 iron, 4 sulfur cluster binding
IL332_13765	COG0243	molybdopterin cofactor binding
IL332_13775	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IL332_13775	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
IL332_13780	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IL332_13785	COG3850	Histidine kinase
IL332_13790	COG2197	response regulator
IL332_13815	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IL332_13825	COG0121	glutamine amidotransferase
IL332_13830	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IL332_13835	COG1960	acyl-CoA dehydrogenase activity
IL332_13840	COG3437	response regulator, receiver
IL332_13840	COG0784	Response regulator, receiver
IL332_13850	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IL332_13855	COG0328	RNA-DNA hybrid ribonuclease activity
IL332_13860	COG2226	methyltransferase
IL332_13865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IL332_13870	COG1388	LysM domain
IL332_13870	COG0741	lytic transglycosylase activity
IL332_13885	COG1607	acyl-coa hydrolase
IL332_13900	COG0741	lytic transglycosylase activity
IL332_13910	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IL332_13935	COG0729	surface antigen
IL332_13945	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IL332_13955	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IL332_13985	COG2951	lytic endotransglycosylase activity
IL332_13990	COG1846	Transcriptional regulator
IL332_14000	COG0033	Phosphoglucomutase
IL332_14005	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
IL332_14015	COG0596	Alpha beta hydrolase
IL332_14030	COG0716	FMN binding
IL332_14040	COG0735	belongs to the Fur family
IL332_14045	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IL332_14055	COG1263	PTS System
IL332_14055	COG2190	(PTS) system
IL332_14055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IL332_14060	COG0363	glucosamine-6-phosphate deaminase activity
IL332_14065	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IL332_14070	COG1940	carbohydrate kinase activity
IL332_14070	COG1846	Transcriptional regulator
IL332_14075	COG2194	sulfuric ester hydrolase activity
IL332_14080	COG0217	transcriptional regulatory protein
IL332_14085	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IL332_14090	COG1801	Protein of unknown function DUF72
IL332_14095	COG4106	trans-aconitate 2-methyltransferase activity
IL332_14100	COG0500	methyltransferase
IL332_14120	COG0583	DNA-binding transcription factor activity
IL332_14125	COG0791	NLP P60 protein
IL332_14140	COG1309	transcriptional regulator
IL332_14175	COG0534	Mate efflux family protein
IL332_14185	COG2841	Protein conserved in bacteria
IL332_14190	COG1013	pyruvate-flavodoxin oxidoreductase activity
IL332_14190	COG0674	pyruvate-flavodoxin oxidoreductase activity
IL332_14190	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IL332_14190	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IL332_14200	COG3217	Mosc domain protein beta barrel domain protein
IL332_14200	COG0633	Ferredoxin
IL332_14200	COG3217	Mosc domain protein beta barrel domain protein
IL332_14200	COG0633	Ferredoxin
IL332_14205	COG0501	Belongs to the peptidase M48B family
IL332_14215	COG1073	alpha beta
IL332_14215	COG2226	methyltransferase
IL332_14220	COG0156	8-amino-7-oxononanoate synthase activity
IL332_14225	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IL332_14245	COG0017	Asparaginyl-tRNA synthetase
IL332_14250	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IL332_14260	COG1473	amidohydrolase
IL332_14275	COG1393	Belongs to the ArsC family
IL332_14280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IL332_14285	COG1876	peptidase activity
IL332_14295	COG3263	regulation of cellular component size
IL332_14305	COG1280	lysine exporter protein (LysE YggA)
IL332_14330	COG1957	nucleoside hydrolase
IL332_14335	COG0564	pseudouridine synthase activity
IL332_14350	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IL332_14355	COG0702	epimerase
IL332_14360	COG2914	Belongs to the UPF0125 (RnfH) family
IL332_14365	COG2867	negative regulation of translational initiation
IL332_14370	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IL332_14390	COG3153	acetyltransferase
IL332_14420	COG0259	pyridoxamine-phosphate oxidase activity
IL332_14435	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IL332_14435	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IL332_14440	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IL332_14465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IL332_14470	COG1138	Cytochrome C-type biogenesis protein
IL332_14475	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
IL332_14480	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IL332_14485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IL332_14505	COG0835	chemotaxis
IL332_14520	COG1360	Flagellar Motor Protein
IL332_14525	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IL332_14530	COG2201	protein-glutamate methylesterase activity
IL332_14540	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
IL332_14565	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IL332_14575	COG1684	flagellar biosynthetic protein fliR
IL332_14630	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IL332_14640	COG1677	Flagellar hook-basal body complex protein FliE
IL332_14655	COG1393	Belongs to the ArsC family
IL332_14660	COG0798	PFAM Bile acid sodium symporter
IL332_14665	COG0640	Transcriptional regulator
IL332_14675	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IL332_14690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IL332_14695	COG0444	Belongs to the ABC transporter superfamily
IL332_14700	COG4608	Belongs to the ABC transporter superfamily
IL332_14710	COG2971	BadF BadG BcrA BcrD
IL332_14720	COG0840	transmembrane signaling receptor activity
IL332_14740	COG3724	N-succinylarginine dihydrolase activity
IL332_14745	COG0616	signal peptide processing
IL332_14750	COG1028	Short-chain dehydrogenase reductase Sdr
IL332_14755	COG0583	DNA-binding transcription factor activity
IL332_14765	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IL332_14775	COG0583	DNA-binding transcription factor activity
IL332_14780	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IL332_14785	COG1881	PFAM PEBP family protein
IL332_14795	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
IL332_14795	COG3408	Glycogen debranching enzyme
IL332_14800	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IL332_14805	COG0739	heme binding
IL332_14810	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IL332_14825	COG0251	oxidation-reduction process
IL332_14840	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IL332_14850	COG3091	SprT-like family
IL332_14860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IL332_14865	COG0189	ligase activity
IL332_14875	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IL332_14880	COG0583	DNA-binding transcription factor activity
IL332_14895	COG1115	amino acid carrier protein
IL332_14900	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IL332_14915	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IL332_14925	COG1301	dicarboxylic acid transport
IL332_14930	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IL332_14935	COG2912	Transglutaminase-like superfamily
IL332_14945	COG2890	protein-(glutamine-N5) methyltransferase activity
IL332_14950	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IL332_14955	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IL332_14960	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IL332_14965	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IL332_14975	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IL332_14980	COG0193	aminoacyl-tRNA hydrolase activity
IL332_14985	COG0012	GTP binding
IL332_15030	COG0471	metal ion transport
IL332_15030	COG0490	domain, Protein
IL332_15040	COG0657	acetylesterase activity
IL332_15055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IL332_15070	COG1012	belongs to the aldehyde dehydrogenase family
IL332_15080	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IL332_15095	COG0180	Tryptophanyl-tRNA synthetase
IL332_15100	COG0546	phosphoglycolate phosphatase activity
IL332_15105	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IL332_15110	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IL332_15120	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IL332_15125	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IL332_15155	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IL332_15160	COG0583	DNA-binding transcription factor activity
IL332_15175	COG0583	DNA-binding transcription factor activity
IL332_15190	COG0739	heme binding
IL332_15200	COG1511	domain protein
IL332_15200	COG3264	Mechanosensitive ion channel
IL332_15205	COG0584	glycerophosphoryl diester phosphodiesterase
IL332_15215	COG1053	succinate dehydrogenase
IL332_15220	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IL332_15225	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
IL332_15230	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
IL332_15245	COG3214	Protein conserved in bacteria
IL332_15250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IL332_15270	COG0300	oxidoreductase activity
IL332_15290	COG4067	protein conserved in archaea
IL332_15290	COG0189	ligase activity
IL332_15305	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IL332_15335	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IL332_15345	COG2199	diguanylate cyclase activity
IL332_15355	COG2199	diguanylate cyclase activity
IL332_15360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IL332_15375	COG1335	isochorismatase
IL332_15380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IL332_15385	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IL332_15390	COG1702	phosphate starvation-inducible protein PhoH
IL332_15395	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IL332_15400	COG4535	Mg2 and Co2 transporter CorC
IL332_15405	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IL332_15410	COG2888	peptidyl-tyrosine sulfation
IL332_15415	COG0495	leucyl-tRNA aminoacylation
IL332_15430	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IL332_15435	COG0799	negative regulation of ribosome biogenesis
IL332_15440	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IL332_15445	COG0768	penicillin binding
IL332_15450	COG0772	Belongs to the SEDS family
IL332_15455	COG2951	lytic endotransglycosylase activity
IL332_15460	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IL332_15465	COG1686	Belongs to the peptidase S11 family
IL332_15470	COG2921	Belongs to the UPF0250 family
IL332_15475	COG0321	lipoyl(octanoyl) transferase activity
IL332_15480	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IL332_15500	COG0326	Molecular chaperone. Has ATPase activity
IL332_15535	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IL332_15565	COG1970	mechanosensitive ion channel activity
IL332_15570	COG4974	Belongs to the 'phage' integrase family
IL332_15580	COG0312	modulator of DNA gyrase
IL332_15600	COG0826	peptidase U32
IL332_15605	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IL332_15610	COG1422	Protein of unknown function (DUF1090)
IL332_15615	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IL332_15620	COG2211	Major facilitator Superfamily
IL332_15625	COG1185	polyribonucleotide nucleotidyltransferase activity
IL332_15630	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IL332_15635	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IL332_15640	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IL332_15645	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IL332_15650	COG0195	Participates in both transcription termination and antitermination
IL332_15655	COG0779	Required for maturation of 30S ribosomal subunits
IL332_15670	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IL332_15675	COG0149	triose-phosphate isomerase activity
IL332_15680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IL332_15685	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IL332_15695	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IL332_15700	COG1534	Rna-binding protein
IL332_15715	COG1360	Flagellar Motor Protein
IL332_15720	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IL332_15725	COG1722	exodeoxyribonuclease VII activity
IL332_15730	COG0142	geranyltranstransferase activity
IL332_15735	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IL332_15740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IL332_15745	COG0601	transmembrane transport
IL332_15755	COG4172	Belongs to the ABC transporter superfamily
IL332_15760	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IL332_15765	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IL332_15770	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IL332_15775	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IL332_15790	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IL332_15790	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IL332_15795	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IL332_15805	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IL332_15815	COG3381	protein complex oligomerization
IL332_15830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IL332_15835	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IL332_15840	COG0511	ligase activity, forming carbon-carbon bonds
IL332_15845	COG0439	Biotin carboxylase
IL332_15850	COG3924	membrane
IL332_15855	COG4145	pantothenate transmembrane transporter activity
IL332_15860	COG2190	(PTS) system
IL332_15860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IL332_15860	COG1263	PTS System
IL332_15865	COG0583	DNA-binding transcription factor activity
IL332_15870	COG0604	alcohol dehydrogenase
IL332_15875	COG2264	protein methyltransferase activity
IL332_15880	COG0110	maltose O-acetyltransferase activity
IL332_15895	COG1902	pentaerythritol trinitrate reductase activity
IL332_15895	COG0446	pyridine nucleotide-disulphide oxidoreductase
IL332_15900	COG0616	signal peptide processing
IL332_15920	COG3139	Protein of unknown function (DUF1315)
IL332_15925	COG0252	asparaginase activity
IL332_15930	COG0786	glutamate:sodium symporter activity
IL332_15945	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IL332_15950	COG0384	phenazine biosynthesis protein PhzF
IL332_15955	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IL332_15960	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IL332_15965	COG0175	sulfate reduction
IL332_15970	COG2113	Glycine betaine
IL332_15975	COG4176	ABC-type proline glycine betaine transport system permease component
IL332_15980	COG4175	Glycine betaine
IL332_15990	COG3610	response to peptide
IL332_15995	COG2966	Psort location CytoplasmicMembrane, score
IL332_16005	COG0521	Mo-molybdopterin cofactor biosynthetic process
IL332_16030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IL332_16035	COG2146	nitrite reductase [NAD(P)H] activity
IL332_16035	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IL332_16040	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IL332_16040	COG2146	nitrite reductase [NAD(P)H] activity
IL332_16050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IL332_16055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IL332_16055	COG1116	anion transmembrane transporter activity
IL332_16065	COG1648	precorrin-2 dehydrogenase activity
IL332_16065	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IL332_16070	COG0243	molybdopterin cofactor binding
IL332_16095	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IL332_16110	COG1073	alpha beta
IL332_16115	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
IL332_16120	COG2195	Cleaves the N-terminal amino acid of tripeptides
IL332_16125	COG4608	Belongs to the ABC transporter superfamily
IL332_16130	COG0444	Belongs to the ABC transporter superfamily
IL332_16140	COG4239	(ABC) transporter, permease
IL332_16145	COG4174	ABC transporter (Permease)
IL332_16150	COG4206	TonB-dependent receptor
IL332_16160	COG0811	peptide transport
IL332_16165	COG0811	peptide transport
IL332_16170	COG0848	biopolymer transport protein
IL332_16220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IL332_16225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IL332_16230	COG0840	transmembrane signaling receptor activity
IL332_16240	COG1278	Cold shock
IL332_16280	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IL332_16285	COG1162	GTPase activity
IL332_16290	COG0688	phosphatidylethanolamine metabolic process
IL332_16295	COG4628	conserved protein (DUF2132)
IL332_16315	COG5001	Diguanylate cyclase
IL332_16315	COG3300	MHYT domain
IL332_16320	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
IL332_16410	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IL332_16430	COG0582	viral genome integration into host DNA
IL332_16485	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IL332_16490	COG2897	thiosulfate sulfurtransferase activity
IL332_16495	COG2066	Belongs to the glutaminase family
IL332_16500	COG3171	Protein conserved in bacteria
IL332_16505	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IL332_16510	COG4935	Belongs to the peptidase S8 family
IL332_16510	COG2234	aminopeptidase activity
IL332_16515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IL332_16520	COG2200	EAL domain
IL332_16525	COG1090	epimerase
IL332_16535	COG4181	ATPase activity
IL332_16540	COG2755	lipolytic protein G-D-S-L family
IL332_16545	COG0835	chemotaxis
IL332_16545	COG0784	Response regulator, receiver
IL332_16555	COG0517	IMP dehydrogenase activity
IL332_16555	COG0516	GMP reductase activity
IL332_16560	COG0488	(ABC) transporter
IL332_16570	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IL332_16595	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
IL332_16605	COG0789	Transcriptional regulator
IL332_16615	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IL332_16625	COG0668	transmembrane transport
IL332_16635	COG2731	YhcH YjgK YiaL family protein
IL332_16645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IL332_16650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IL332_16655	COG3227	Zinc metalloprotease (Elastase)
IL332_16660	COG0583	DNA-binding transcription factor activity
IL332_16775	COG0569	domain protein
IL332_16775	COG2985	domain, Protein
IL332_16780	COG1272	protein, Hemolysin III
IL332_16785	COG0076	glutamate decarboxylase activity
IL332_16790	COG2917	probably involved in intracellular septation
IL332_16795	COG2350	Protein conserved in bacteria
IL332_16805	COG1555	photosystem II stabilization
IL332_16810	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IL332_16815	COG3104	oligopeptide transport
IL332_16850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IL332_16865	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IL332_16895	COG0316	Belongs to the HesB IscA family
IL332_16910	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IL332_16925	COG0671	phosphoesterase, PA-phosphatase related
IL332_16935	COG0583	DNA-binding transcription factor activity
IL332_16940	COG2076	Multidrug Resistance protein
IL332_16950	COG0346	lactoylglutathione lyase activity
IL332_16955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IL332_16970	COG1489	DNA binding
IL332_16975	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IL332_16990	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IL332_16995	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IL332_17000	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IL332_17010	COG0842	Transport permease protein
IL332_17015	COG1131	(ABC) transporter
IL332_17030	COG0163	prenyltransferase activity
IL332_17035	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IL332_17040	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IL332_17055	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
IL332_17070	COG1136	(ABC) transporter
IL332_17090	COG0840	transmembrane signaling receptor activity
IL332_17115	COG0529	Catalyzes the synthesis of activated sulfate
IL332_17120	COG0471	metal ion transport
IL332_17120	COG3273	potassium ion transport
IL332_17125	COG2895	sulfate adenylyltransferase (ATP) activity
IL332_17130	COG0175	sulfate reduction
IL332_17140	COG0330	HflC and HflK could
IL332_17145	COG1585	Membrane protein implicated in regulation of membrane protease activity
IL332_17155	COG0673	inositol 2-dehydrogenase activity
IL332_17165	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IL332_17170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IL332_17175	COG3036	rescue of stalled ribosome
IL332_17190	COG0138	bifunctional purine biosynthesis protein purh
IL332_17285	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IL332_17290	COG0358	DNA primase activity
IL332_17295	COG1610	YqeY-like protein
IL332_17300	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IL332_17305	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IL332_17315	COG4942	peptidase
IL332_17315	COG1388	LysM domain
IL332_17320	COG1238	metal cluster binding
IL332_17325	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IL332_17330	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IL332_17335	COG0585	pseudouridine synthase activity
IL332_17345	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IL332_17350	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IL332_17355	COG0148	phosphopyruvate hydratase activity
IL332_17360	COG0504	CTP synthase activity
IL332_17365	COG3956	TIGRFAM MazG family protein
IL332_17370	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IL332_17385	COG4807	Protein conserved in bacteria
IL332_17390	COG3023	N-Acetylmuramoyl-L-alanine amidase
IL332_17395	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IL332_17400	COG1381	Involved in DNA repair and RecF pathway recombination
IL332_17410	COG0571	ribonuclease III activity
IL332_17415	COG0681	Belongs to the peptidase S26 family
IL332_17420	COG0481	GTPase activity
IL332_17440	COG1595	DNA-templated transcription, initiation
IL332_17455	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IL332_17465	COG0583	DNA-binding transcription factor activity
IL332_17505	COG0126	phosphoglycerate kinase activity
IL332_17510	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IL332_17515	COG1940	carbohydrate kinase activity
IL332_17520	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IL332_17525	COG2816	NAD+ diphosphatase activity
IL332_17530	COG4991	sh3 domain protein
IL332_17535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IL332_17550	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IL332_17555	COG1028	Short-chain dehydrogenase reductase Sdr
IL332_17565	COG1505	serine-type exopeptidase activity
IL332_17570	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IL332_17575	COG0765	amino acid transport
IL332_17580	COG0765	amino acid transport
IL332_17585	COG1126	abc transporter atp-binding protein
IL332_17590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IL332_17595	COG3174	membrane
IL332_17600	COG0110	maltose O-acetyltransferase activity
IL332_17625	COG0583	DNA-binding transcription factor activity
IL332_17630	COG0165	Argininosuccinate lyase
IL332_17635	COG0137	argininosuccinate synthase activity
IL332_17645	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IL332_17650	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IL332_17660	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IL332_17670	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IL332_17705	COG0583	DNA-binding transcription factor activity
IL332_17710	COG1380	Effector of murein hydrolase LrgA
IL332_17715	COG1346	cytolysis
IL332_17720	COG0527	aspartate kinase activity
IL332_17720	COG0460	homoserine dehydrogenase
IL332_17745	COG0814	amino acid
IL332_17750	COG1218	3'(2'),5'-bisphosphate nucleotidase
IL332_17755	COG0494	nUDIX hydrolase
IL332_17760	COG1011	Hydrolase
IL332_17775	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IL332_17790	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IL332_17800	COG3156	type II secretion system protein K
IL332_17810	COG4795	General secretion pathway protein
IL332_17815	COG2165	general secretion pathway protein
IL332_17825	COG2165	general secretion pathway protein
IL332_17830	COG1459	type II secretion system
IL332_17835	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IL332_17845	COG3031	protein transport across the cell outer membrane
IL332_17855	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IL332_17860	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IL332_17875	COG0456	acetyltransferase
IL332_17880	COG3133	Outer membrane lipoprotein
IL332_17885	COG3025	triphosphatase activity
IL332_17890	COG1392	Phosphate transport regulator
IL332_17895	COG0306	phosphate transporter
IL332_17900	COG0617	tRNA 3'-terminal CCA addition
IL332_17905	COG3409	Peptidoglycan-binding domain 1 protein
IL332_17905	COG3267	Type II secretory pathway component ExeA
IL332_17915	COG1194	a g-specific adenine glycosylase
IL332_17920	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
IL332_17935	COG3240	lipase activity
IL332_17945	COG3009	Protein conserved in bacteria
IL332_17950	COG3008	intermembrane lipid transfer
IL332_17950	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IL332_17955	COG2995	paraquat-inducible protein a
IL332_17965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IL332_17970	COG2203	Gaf domain
IL332_17970	COG5001	Diguanylate cyclase
IL332_17970	COG3706	GGDEF domain
IL332_17970	COG4251	negative regulation of phosphorylation
IL332_17975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IL332_17980	COG2813	Specifically methylates the guanine in position
IL332_17985	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IL332_17990	COG0297	glycogen (starch) synthase activity
IL332_18030	COG1757	Na H antiporter
IL332_18035	COG0583	DNA-binding transcription factor activity
IL332_18040	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IL332_18045	COG3842	ATPase activity
IL332_18055	COG1177	transmembrane transport
IL332_18060	COG1012	belongs to the aldehyde dehydrogenase family
IL332_18065	COG0109	protoheme IX farnesyltransferase activity
IL332_18095	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
IL332_18105	COG1565	acr, cog1565
IL332_18105	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IL332_18110	COG1444	tRNA N-acetyltransferase activity
IL332_18130	COG1803	Methylglyoxal synthase
IL332_18145	COG0252	asparaginase activity
IL332_18155	COG1609	Transcriptional regulator
IL332_18165	COG1940	carbohydrate kinase activity
IL332_18170	COG1447	Phosphotransferase system cellobiose-specific component IIA
IL332_18175	COG2723	6-phospho-beta-galactosidase activity
IL332_18180	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IL332_18180	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IL332_18185	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IL332_18210	COG1263	PTS System
IL332_18210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IL332_18215	COG0366	Alpha amylase catalytic
IL332_18220	COG0110	maltose O-acetyltransferase activity
IL332_18225	COG1522	sequence-specific DNA binding
IL332_18230	COG5006	permease, DMT superfamily
IL332_18275	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IL332_18280	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IL332_18300	COG0523	cobalamin synthesis protein
IL332_18310	COG1280	lysine exporter protein (LysE YggA)
IL332_18320	COG2200	EAL domain
IL332_18325	COG1049	propionate catabolic process, 2-methylcitrate cycle
IL332_18330	COG1752	Esterase of the alpha-beta hydrolase superfamily
IL332_18335	COG0840	transmembrane signaling receptor activity
IL332_18340	COG0840	transmembrane signaling receptor activity
IL332_18350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IL332_18360	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IL332_18365	COG2186	Transcriptional regulator
IL332_18390	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IL332_18395	COG1459	type II secretion system
IL332_18410	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
IL332_18415	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IL332_18420	COG0494	nUDIX hydrolase
IL332_18430	COG0653	protein targeting
IL332_18440	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IL332_18445	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IL332_18450	COG0849	cell division
IL332_18455	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IL332_18460	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IL332_18465	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IL332_18470	COG0772	Belongs to the SEDS family
IL332_18475	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IL332_18480	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IL332_18485	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IL332_18490	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IL332_18500	COG3116	cell division
IL332_18505	COG0275	rRNA processing
IL332_18510	COG2001	Belongs to the MraZ family
IL332_18520	COG1388	LysM domain
IL332_18520	COG0741	lytic transglycosylase activity
IL332_18535	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IL332_18540	COG1191	sigma factor activity
IL332_18565	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IL332_18570	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IL332_18590	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IL332_18595	COG1256	bacterial-type flagellum assembly
IL332_18595	COG4786	Flagellar basal body rod
IL332_18605	COG1706	bacterial-type flagellum-dependent cell motility
IL332_18610	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
IL332_18615	COG4786	Flagellar basal body rod
IL332_18625	COG1749	Flagellar hook protein flgE
IL332_18640	COG1815	bacterial-type flagellum-dependent cell motility
IL332_18645	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
IL332_18675	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IL332_18685	COG1677	Flagellar hook-basal body complex protein FliE
IL332_18710	COG1987	bacterial-type flagellum assembly
IL332_18735	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IL332_18740	COG3107	peptidoglycan biosynthetic process
IL332_18745	COG0792	nuclease activity
IL332_18750	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IL332_18755	COG2823	Periplasmic or secreted lipoprotein
IL332_18760	COG2969	positive regulation of protein catabolic process
IL332_18765	COG0625	glutathione transferase activity
IL332_18770	COG2857	Cytochrome c1
IL332_18775	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IL332_18780	COG0723	plastoquinol--plastocyanin reductase activity
IL332_18785	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IL332_18790	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IL332_18795	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IL332_18805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IL332_18810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IL332_18840	COG3964	amidohydrolase
IL332_18860	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IL332_18865	COG1660	Displays ATPase and GTPase activities
IL332_18870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IL332_18880	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IL332_18885	COG1137	ATPase activity
IL332_18890	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IL332_18900	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IL332_18905	COG0517	IMP dehydrogenase activity
IL332_18905	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IL332_18915	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IL332_18920	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IL332_18925	COG2854	intermembrane phospholipid transfer
IL332_18935	COG5007	Belongs to the BolA IbaG family
IL332_18940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IL332_18945	COG0312	modulator of DNA gyrase
IL332_18950	COG3028	Belongs to the UPF0307 family
IL332_18960	COG2926	Belongs to the UPF0265 family
IL332_18990	COG1396	sequence-specific DNA binding
IL332_18995	COG3135	benzoate transporter
IL332_19025	COG3047	cAMP biosynthetic process
IL332_19030	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IL332_19035	COG2197	response regulator
IL332_19055	COG1278	Cold shock
IL332_19085	COG3706	GGDEF domain
IL332_19090	COG0347	Belongs to the P(II) protein family
IL332_19095	COG0004	ammonium transporteR
IL332_19105	COG0346	lactoylglutathione lyase activity
IL332_19120	COG1074	ATP-dependent DNA helicase activity
IL332_19130	COG2259	Doxx family
IL332_19135	COG1741	Belongs to the pirin family
IL332_19145	COG0583	DNA-binding transcription factor activity
IL332_19170	COG1175	transmembrane transport
IL332_19180	COG3842	ATPase activity
IL332_19215	COG0753	catalase activity
IL332_19240	COG0628	permease
IL332_19250	COG2957	Belongs to the agmatine deiminase family
IL332_19265	COG2957	Belongs to the agmatine deiminase family
IL332_19270	COG0583	DNA-binding transcription factor activity
IL332_19285	COG1461	Dihydroxyacetone kinase
IL332_19290	COG2376	Dihydroxyacetone kinase
IL332_19295	COG2252	PERMEase
IL332_19330	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IL332_19335	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IL332_19340	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IL332_19345	COG0049	tRNA binding
IL332_19350	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IL332_19355	COG2168	tRNA wobble position uridine thiolation
IL332_19365	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IL332_19370	COG0251	oxidation-reduction process
IL332_19380	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IL332_19385	COG0085	RNA polymerase activity
IL332_19390	COG0222	ribosome binding
IL332_19395	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IL332_19400	COG0081	regulation of translation
IL332_19405	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IL332_19410	COG0250	Participates in transcription elongation, termination and antitermination
IL332_19425	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IL332_19450	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IL332_19455	COG0569	domain protein
IL332_19465	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IL332_19470	COG3005	denitrification pathway
IL332_19475	COG0243	molybdopterin cofactor binding
IL332_19510	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IL332_19520	COG2204	response regulator
IL332_19530	COG2205	protein histidine kinase activity
IL332_19550	COG0517	IMP dehydrogenase activity
IL332_19550	COG0516	GMP reductase activity
IL332_19560	COG1522	sequence-specific DNA binding
IL332_19565	COG2502	aspartate--ammonia ligase
IL332_19570	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IL332_19575	COG0542	response to heat
IL332_19585	COG0564	pseudouridine synthase activity
IL332_19590	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IL332_19595	COG3681	Belongs to the UPF0597 family
IL332_19600	COG2964	Protein conserved in bacteria
IL332_19605	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IL332_19610	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IL332_19615	COG1979	alcohol dehydrogenase
IL332_19620	COG2207	Transcriptional regulator
IL332_19625	COG3040	lipid binding
IL332_19665	COG0540	Belongs to the ATCase OTCase family
IL332_19670	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
IL332_19675	COG1438	arginine binding
IL332_19680	COG1288	antiporter activity
IL332_19685	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IL332_19730	COG1609	Transcriptional regulator
IL332_19735	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IL332_19745	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IL332_19750	COG2017	converts alpha-aldose to the beta-anomer
IL332_19755	COG0667	Aldo Keto reductase
IL332_19760	COG1968	undecaprenyl-diphosphatase activity
IL332_19765	COG3806	Anti-sigma factor
IL332_19770	COG1595	DNA-templated transcription, initiation
IL332_19790	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IL332_19795	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IL332_19800	COG0477	Major facilitator Superfamily
IL332_19815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IL332_19820	COG1131	(ABC) transporter
IL332_19825	COG0842	Transport permease protein
IL332_19830	COG0842	Transport permease protein
IL332_19835	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IL332_19845	COG2116	formate transmembrane transporter activity
IL332_19855	COG2239	Acts as a magnesium transporter
IL332_19860	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IL332_19865	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IL332_19875	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IL332_19885	COG0514	ATP-dependent DNA helicase (RecQ)
IL332_19890	COG2050	protein possibly involved in aromatic compounds catabolism
IL332_19905	COG2258	MOSC domain
IL332_19910	COG1177	transmembrane transport
IL332_19915	COG1176	ABC-type spermidine putrescine transport system, permease component I
IL332_19920	COG3842	ATPase activity
IL332_19940	COG0174	glutamine synthetase
IL332_19960	COG3045	CreA protein
IL332_19965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IL332_19970	COG0443	Heat shock 70 kDa protein
IL332_19985	COG0366	Alpha amylase catalytic
IL332_20000	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IL332_20005	COG0745	RESPONSE REGULATOR receiver
IL332_20010	COG2205	protein histidine kinase activity
IL332_20020	COG0281	malic enzyme
IL332_20025	COG0702	epimerase
IL332_20030	COG0254	rRNA binding
IL332_20035	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IL332_20040	COG1309	transcriptional regulator
IL332_20060	COG0129	dihydroxy-acid dehydratase activity
IL332_20070	COG3978	acetolactate synthase activity
IL332_20080	COG0606	chelatase, subunit chli
IL332_20085	COG0204	Acyl-transferase
IL332_20090	COG0204	Acyl-transferase
IL332_20105	COG1335	isochorismatase
IL332_20115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IL332_20120	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IL332_20130	COG3084	Protein conserved in bacteria
IL332_20135	COG3706	GGDEF domain
IL332_20135	COG4251	negative regulation of phosphorylation
IL332_20135	COG5001	Diguanylate cyclase
IL332_20135	COG2203	Gaf domain
IL332_20150	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IL332_20155	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IL332_20160	COG1561	YicC-like family, N-terminal region
IL332_20175	COG0859	PFAM glycosyl transferase family 9
IL332_20180	COG0463	Glycosyl transferase, family 2
IL332_20185	COG0859	PFAM glycosyl transferase family 9
IL332_20190	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IL332_20195	COG2990	Protein conserved in bacteria
IL332_20200	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IL332_20210	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IL332_20215	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IL332_20220	COG2003	Belongs to the UPF0758 family
IL332_20225	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IL332_20230	COG0756	dUTP diphosphatase activity
IL332_20235	COG1309	transcriptional regulator
IL332_20245	COG0668	transmembrane transport
IL332_20255	COG0166	Belongs to the GPI family
IL332_20260	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IL332_20265	COG0583	DNA-binding transcription factor activity
IL332_20275	COG0045	succinate-CoA ligase (ADP-forming) activity
IL332_20275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IL332_20275	COG1042	CoA-binding domain protein
IL332_20305	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
IL332_20315	COG1739	Uncharacterized protein family UPF0029
IL332_20320	COG0006	proline dipeptidase activity
IL332_20325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IL332_20330	COG1024	Enoyl-CoA hydratase
IL332_20330	COG1250	3-hydroxyacyl-CoA dehydrogenase
IL332_20335	COG0183	Belongs to the thiolase family
IL332_20360	COG0425	Belongs to the sulfur carrier protein TusA family
IL332_20365	COG0251	oxidation-reduction process
IL332_20385	COG2885	chlorophyll binding
IL332_20395	COG1335	isochorismatase
IL332_20400	COG2818	Glycosylase
IL332_20405	COG0752	glycyl-tRNA synthetase alpha subunit
IL332_20410	COG0751	glycine-tRNA ligase activity
IL332_20420	COG4251	negative regulation of phosphorylation
IL332_20420	COG5001	Diguanylate cyclase
IL332_20420	COG2203	Gaf domain
IL332_20420	COG3706	GGDEF domain
IL332_20435	COG0814	amino acid
IL332_20445	COG3033	Beta-eliminating lyase
IL332_20455	COG0348	domain, Protein
IL332_20465	COG0446	pyridine nucleotide-disulphide oxidoreductase
IL332_20470	COG0426	domain, Protein
IL332_20470	COG1773	rubredoxin
IL332_20475	COG3604	Transcriptional regulator
IL332_20480	COG1609	Transcriptional regulator
IL332_20520	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IL332_20535	COG2960	long-chain fatty acid transporting porin activity
IL332_20560	COG3118	belongs to the thioredoxin family
IL332_20565	COG0513	Belongs to the DEAD box helicase family
IL332_20570	COG0248	Ppx GppA phosphatase
IL332_20580	COG0742	ribosomal rna small subunit methyltransferase
IL332_20590	COG0339	signal peptide processing
IL332_20600	COG0084	hydrolase, TatD family'
IL332_20605	COG0805	protein transport
IL332_20610	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IL332_20615	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IL332_20620	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IL332_20625	COG3165	ubiquinone biosynthetic process from chorismate
IL332_20635	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IL332_20640	COG0402	S-adenosylhomocysteine deaminase activity
IL332_20675	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IL332_20680	COG0848	biopolymer transport protein
IL332_20685	COG0811	peptide transport
IL332_20690	COG0811	peptide transport
IL332_20700	COG2771	luxR family
IL332_20705	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IL332_20710	COG1349	DNA-binding transcription factor activity
IL332_20715	COG0745	RESPONSE REGULATOR receiver
IL332_20720	COG2205	protein histidine kinase activity
IL332_20730	COG4452	Inner membrane protein CreD
IL332_20735	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IL332_20740	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IL332_20745	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IL332_20750	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IL332_20755	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IL332_20760	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IL332_20765	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IL332_20775	COG0356	it plays a direct role in the translocation of protons across the membrane
IL332_20785	COG1475	DNA binding
IL332_20790	COG1192	Involved in chromosome partitioning
IL332_20795	COG0357	Ribosomal RNA small subunit methyltransferase G
IL332_20800	COG0445	tRNA wobble uridine modification
IL332_20805	COG0716	FMN binding
IL332_20810	COG4774	siderophore transport
IL332_20815	COG4615	Cyclic peptide transporter
IL332_20820	COG1120	ATPase activity
IL332_20825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IL332_20835	COG3550	peptidyl-serine autophosphorylation
IL332_20890	COG4974	Belongs to the 'phage' integrase family
IL332_20895	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IL332_20900	COG0706	membrane insertase activity
IL332_20905	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IL332_20910	COG0594	ribonuclease P activity
IL332_20915	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IL332_20920	COG1126	abc transporter atp-binding protein