locus-tag	class	description
ACGSH8M1_000010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ACGSH8M1_000020	COG0592	DNA-directed DNA polymerase activity
ACGSH8M1_000040	COG0187	DNA topoisomerase II activity
ACGSH8M1_000050	COG2207	Transcriptional regulator
ACGSH8M1_000070	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ACGSH8M1_000080	COG0071	Belongs to the small heat shock protein (HSP20) family
ACGSH8M1_000090	COG0071	Belongs to the small heat shock protein (HSP20) family
ACGSH8M1_000100	COG3977	Valine--pyruvate aminotransferase
ACGSH8M1_000130	COG2814	Major facilitator Superfamily
ACGSH8M1_000150	COG0745	RESPONSE REGULATOR receiver
ACGSH8M1_000160	COG2205	protein histidine kinase activity
ACGSH8M1_000250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACGSH8M1_000260	COG4191	Histidine kinase
ACGSH8M1_000260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACGSH8M1_000270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACGSH8M1_000280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACGSH8M1_000290	COG1309	transcriptional regulator
ACGSH8M1_000310	COG0561	phosphatase activity
ACGSH8M1_000320	COG2267	carboxylic ester hydrolase activity
ACGSH8M1_000340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACGSH8M1_000350	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACGSH8M1_000360	COG1758	RNA polymerase activity
ACGSH8M1_000380	COG0859	PFAM glycosyl transferase family 9
ACGSH8M1_000390	COG3642	lipopolysaccharide core region biosynthetic process
ACGSH8M1_000470	COG0589	response to stress
ACGSH8M1_000480	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ACGSH8M1_000490	COG3706	GGDEF domain
ACGSH8M1_000500	COG1528	Iron-storage protein
ACGSH8M1_000510	COG2081	HI0933 family
ACGSH8M1_000520	COG2223	nitrite transmembrane transporter activity
ACGSH8M1_000530	COG1280	lysine exporter protein (LysE YggA)
ACGSH8M1_000560	COG5433	transposase activity
ACGSH8M1_000580	COG3188	usher protein
ACGSH8M1_000620	COG2205	protein histidine kinase activity
ACGSH8M1_000620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACGSH8M1_000640	COG3275	phosphorelay sensor kinase activity
ACGSH8M1_000660	COG3279	Response regulator of the LytR AlgR family
ACGSH8M1_000670	COG2223	nitrite transmembrane transporter activity
ACGSH8M1_000680	COG3385	transposase activity
ACGSH8M1_000690	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ACGSH8M1_000700	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ACGSH8M1_000750	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ACGSH8M1_000760	COG2166	iron-sulfur cluster assembly
ACGSH8M1_000770	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACGSH8M1_000810	COG1063	alcohol dehydrogenase
ACGSH8M1_000840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACGSH8M1_000870	COG3306	glycosyltransferase involved in LPS biosynthesis
ACGSH8M1_000880	COG0859	PFAM glycosyl transferase family 9
ACGSH8M1_000930	COG1609	Transcriptional regulator
ACGSH8M1_000970	COG1580	Controls the rotational direction of flagella during chemotaxis
ACGSH8M1_000980	COG3161	chorismate lyase activity
ACGSH8M1_000990	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ACGSH8M1_001000	COG2937	Belongs to the GPAT DAPAT family
ACGSH8M1_001010	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACGSH8M1_001040	COG0534	Mate efflux family protein
ACGSH8M1_001050	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ACGSH8M1_001060	COG2205	protein histidine kinase activity
ACGSH8M1_001070	COG0745	RESPONSE REGULATOR receiver
ACGSH8M1_001090	COG1045	serine acetyltransferase
ACGSH8M1_001110	COG3074	FtsZ-dependent cytokinesis
ACGSH8M1_001120	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ACGSH8M1_001130	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACGSH8M1_001130	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACGSH8M1_001140	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ACGSH8M1_001150	COG1609	Transcriptional regulator
ACGSH8M1_001160	COG3250	beta-galactosidase activity
ACGSH8M1_001170	COG2731	YhcH YjgK YiaL family protein
ACGSH8M1_001180	COG0531	amino acid
ACGSH8M1_001190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACGSH8M1_001200	COG0531	amino acid
ACGSH8M1_001210	COG0385	Bile acid
ACGSH8M1_001220	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACGSH8M1_001270	COG0583	DNA-binding transcription factor activity
ACGSH8M1_001340	COG0210	DNA helicase
ACGSH8M1_001380	COG1943	Transposase
ACGSH8M1_001390	COG0583	DNA-binding transcription factor activity
ACGSH8M1_001470	COG1280	lysine exporter protein (LysE YggA)
ACGSH8M1_001490	COG2962	Rard protein
ACGSH8M1_001510	COG1012	belongs to the aldehyde dehydrogenase family
ACGSH8M1_001520	COG1396	sequence-specific DNA binding
ACGSH8M1_001550	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACGSH8M1_001550	COG0519	Catalyzes the synthesis of GMP from XMP
ACGSH8M1_001570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACGSH8M1_001610	COG1322	Protein conserved in bacteria
ACGSH8M1_001620	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ACGSH8M1_001630	COG0569	domain protein
ACGSH8M1_001640	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACGSH8M1_001640	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ACGSH8M1_001650	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ACGSH8M1_001660	COG0242	peptide deformylase activity
ACGSH8M1_001680	COG0758	DNA mediated transformation
ACGSH8M1_001690	COG2922	Belongs to the Smg family
ACGSH8M1_001700	COG0551	DNA topoisomerase type I activity
ACGSH8M1_001710	COG0009	L-threonylcarbamoyladenylate synthase
ACGSH8M1_001720	COG0408	coproporphyrinogen oxidase activity
ACGSH8M1_001730	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ACGSH8M1_001740	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ACGSH8M1_001760	COG3335	DDE superfamily endonuclease
ACGSH8M1_001780	COG3078	GTPase activator activity
ACGSH8M1_001800	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACGSH8M1_001810	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ACGSH8M1_001830	COG3852	Histidine kinase
ACGSH8M1_001850	COG0174	glutamine synthetase
ACGSH8M1_001870	COG1295	ribonuclease BN
ACGSH8M1_001880	COG1490	D-aminoacyl-tRNA deacylase activity
ACGSH8M1_001910	COG0456	acetyltransferase
ACGSH8M1_001930	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACGSH8M1_001940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACGSH8M1_001950	COG2610	gluconate transmembrane transporter activity
ACGSH8M1_001960	COG3265	gluconokinase activity
ACGSH8M1_001970	COG0129	dihydroxy-acid dehydratase activity
ACGSH8M1_001980	COG0800	Aldolase
ACGSH8M1_002010	COG1609	Transcriptional regulator
ACGSH8M1_002030	COG4942	peptidase
ACGSH8M1_002040	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ACGSH8M1_002050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACGSH8M1_002060	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ACGSH8M1_002070	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ACGSH8M1_002080	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ACGSH8M1_002080	COG0316	Belongs to the HesB IscA family
ACGSH8M1_002090	COG1040	competence protein
ACGSH8M1_002100	COG0596	Alpha beta hydrolase
ACGSH8M1_002130	COG2183	response to ionizing radiation
ACGSH8M1_002140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACGSH8M1_002150	COG0745	RESPONSE REGULATOR receiver
ACGSH8M1_002160	COG2205	protein histidine kinase activity
ACGSH8M1_002180	COG0051	transcription antitermination factor activity, RNA binding
ACGSH8M1_002190	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ACGSH8M1_002200	COG0088	Forms part of the polypeptide exit tunnel
ACGSH8M1_002210	COG0089	rRNA binding
ACGSH8M1_002220	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACGSH8M1_002230	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ACGSH8M1_002240	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ACGSH8M1_002250	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ACGSH8M1_002260	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ACGSH8M1_002270	COG0255	Belongs to the universal ribosomal protein uL29 family
ACGSH8M1_002280	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ACGSH8M1_002290	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ACGSH8M1_002300	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ACGSH8M1_002310	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACGSH8M1_002320	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ACGSH8M1_002330	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ACGSH8M1_002340	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ACGSH8M1_002350	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ACGSH8M1_002360	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ACGSH8M1_002370	COG1841	ribosomal large subunit assembly
ACGSH8M1_002380	COG0200	Binds to the 23S rRNA
ACGSH8M1_002390	COG0201	protein transport
ACGSH8M1_002400	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ACGSH8M1_002410	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ACGSH8M1_002420	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ACGSH8M1_002430	COG0202	RNA polymerase activity
ACGSH8M1_002440	COG0203	ribosomal protein L17
ACGSH8M1_002450	COG4584	PFAM Integrase catalytic
ACGSH8M1_002460	COG1484	DNA-dependent DNA replication
ACGSH8M1_002500	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACGSH8M1_002510	COG0583	DNA-binding transcription factor activity
ACGSH8M1_002520	COG4221	oxidoreductase activity
ACGSH8M1_002550	COG1770	oligopeptidase
ACGSH8M1_002580	COG3385	transposase activity
ACGSH8M1_002600	COG3714	YhhN family
ACGSH8M1_002630	COG0583	DNA-binding transcription factor activity
ACGSH8M1_002650	COG1301	dicarboxylic acid transport
ACGSH8M1_002670	COG2095	MarC family integral membrane protein
ACGSH8M1_002690	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACGSH8M1_002710	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ACGSH8M1_002730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACGSH8M1_002780	COG0742	ribosomal rna small subunit methyltransferase
ACGSH8M1_002790	COG0552	protein localization to endoplasmic reticulum
ACGSH8M1_002800	COG2884	Cell division ATP-binding protein ftsE
ACGSH8M1_002810	COG2177	Part of the ABC transporter FtsEX involved in
ACGSH8M1_002830	COG0288	reversible hydration of carbon dioxide
ACGSH8M1_002840	COG2188	Transcriptional regulator
ACGSH8M1_002850	COG1228	amidohydrolase
ACGSH8M1_002860	COG0010	Belongs to the arginase family
ACGSH8M1_002870	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ACGSH8M1_002880	COG2986	histidine ammonia-lyase
ACGSH8M1_002890	COG2801	Transposase and inactivated derivatives
ACGSH8M1_002910	COG0387	Pfam Sodium calcium exchanger
ACGSH8M1_002920	COG2200	EAL domain
ACGSH8M1_003060	COG1459	type II secretion system
ACGSH8M1_003150	COG1077	Cell shape determining protein MreB Mrl
ACGSH8M1_003160	COG1792	Involved in formation and maintenance of cell shape
ACGSH8M1_003170	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ACGSH8M1_003180	COG0424	maF-like protein
ACGSH8M1_003190	COG1530	ribonuclease E activity
ACGSH8M1_003200	COG3164	Protein of unknown function
ACGSH8M1_003210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACGSH8M1_003220	COG0312	modulator of DNA gyrase
ACGSH8M1_003260	COG0477	Major facilitator Superfamily
ACGSH8M1_003280	COG2321	neutral zinc metallopeptidase
ACGSH8M1_003320	COG2963	transposase activity
ACGSH8M1_003330	COG2801	Transposase and inactivated derivatives
ACGSH8M1_003390	COG0582	viral genome integration into host DNA
ACGSH8M1_003440	COG0189	ligase activity
ACGSH8M1_003460	COG0745	RESPONSE REGULATOR receiver
ACGSH8M1_003490	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ACGSH8M1_003500	COG0352	thiamine-phosphate diphosphorylase activity
ACGSH8M1_003510	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ACGSH8M1_003530	COG2022	thiamine diphosphate biosynthetic process
ACGSH8M1_003540	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACGSH8M1_003580	COG2199	diguanylate cyclase activity
ACGSH8M1_003580	COG2203	Gaf domain
ACGSH8M1_003590	COG3932	Exopolysaccharide synthesis, ExoD
ACGSH8M1_003620	COG1733	regulation of RNA biosynthetic process
ACGSH8M1_003670	COG2226	methyltransferase
ACGSH8M1_003690	COG1494	fructose-1,6-bisphosphatase
ACGSH8M1_003710	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACGSH8M1_003720	COG5007	Belongs to the BolA IbaG family
ACGSH8M1_003740	COG2854	intermembrane phospholipid transfer
ACGSH8M1_003750	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ACGSH8M1_003760	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACGSH8M1_003770	COG1127	ABC transporter
ACGSH8M1_003780	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ACGSH8M1_003780	COG0517	IMP dehydrogenase activity
ACGSH8M1_003790	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ACGSH8M1_003810	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ACGSH8M1_003820	COG1137	ATPase activity
ACGSH8M1_003830	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ACGSH8M1_003850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACGSH8M1_003860	COG1660	Displays ATPase and GTPase activities
ACGSH8M1_003870	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACGSH8M1_003910	COG3964	amidohydrolase
ACGSH8M1_003970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACGSH8M1_003980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACGSH8M1_004000	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ACGSH8M1_004010	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ACGSH8M1_004020	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ACGSH8M1_004030	COG0723	plastoquinol--plastocyanin reductase activity
ACGSH8M1_004040	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ACGSH8M1_004050	COG2857	Cytochrome c1
ACGSH8M1_004060	COG0625	glutathione transferase activity
ACGSH8M1_004070	COG2969	positive regulation of protein catabolic process
ACGSH8M1_004080	COG2823	Periplasmic or secreted lipoprotein
ACGSH8M1_004090	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ACGSH8M1_004100	COG0792	nuclease activity
ACGSH8M1_004110	COG3107	peptidoglycan biosynthetic process
ACGSH8M1_004120	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ACGSH8M1_004130	COG2001	Belongs to the MraZ family
ACGSH8M1_004140	COG0275	rRNA processing
ACGSH8M1_004150	COG3116	cell division
ACGSH8M1_004160	COG0768	penicillin binding
ACGSH8M1_004170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ACGSH8M1_004180	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ACGSH8M1_004190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACGSH8M1_004200	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ACGSH8M1_004210	COG0772	Belongs to the SEDS family
ACGSH8M1_004220	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ACGSH8M1_004230	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACGSH8M1_004240	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ACGSH8M1_004250	COG0849	cell division
ACGSH8M1_004260	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACGSH8M1_004270	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ACGSH8M1_004290	COG0653	protein targeting
ACGSH8M1_004310	COG0494	nUDIX hydrolase
ACGSH8M1_004320	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ACGSH8M1_004330	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ACGSH8M1_004350	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ACGSH8M1_004360	COG1459	type II secretion system
ACGSH8M1_004370	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACGSH8M1_004430	COG2186	Transcriptional regulator
ACGSH8M1_004440	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ACGSH8M1_004450	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACGSH8M1_004460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACGSH8M1_004480	COG0840	transmembrane signaling receptor activity
ACGSH8M1_004490	COG0840	transmembrane signaling receptor activity
ACGSH8M1_004500	COG1752	Esterase of the alpha-beta hydrolase superfamily
ACGSH8M1_004510	COG1049	propionate catabolic process, 2-methylcitrate cycle
ACGSH8M1_004520	COG2200	EAL domain
ACGSH8M1_004540	COG1280	lysine exporter protein (LysE YggA)
ACGSH8M1_004560	COG0523	cobalamin synthesis protein
ACGSH8M1_004570	COG0477	Major facilitator Superfamily
ACGSH8M1_004600	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ACGSH8M1_004610	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ACGSH8M1_004680	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ACGSH8M1_004710	COG1546	Belongs to the CinA family
ACGSH8M1_004720	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ACGSH8M1_004730	COG2137	regulation of response to DNA damage stimulus
ACGSH8M1_004740	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ACGSH8M1_004750	COG0527	aspartate kinase activity
ACGSH8M1_004760	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ACGSH8M1_004770	COG1686	Belongs to the peptidase S11 family
ACGSH8M1_004780	COG0586	Pfam SNARE associated Golgi protein
ACGSH8M1_004790	COG1253	flavin adenine dinucleotide binding
ACGSH8M1_004800	COG0525	valine-tRNA ligase activity
ACGSH8M1_004810	COG2927	DNA polymerase III (CHI subunit)
ACGSH8M1_004820	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACGSH8M1_004830	COG0795	lipopolysaccharide-transporting ATPase activity
ACGSH8M1_004840	COG0795	lipopolysaccharide-transporting ATPase activity
ACGSH8M1_004850	COG3385	transposase activity
ACGSH8M1_004870	COG0582	viral genome integration into host DNA
ACGSH8M1_004910	COG2801	Transposase and inactivated derivatives
ACGSH8M1_004930	COG0004	ammonium transporteR
ACGSH8M1_004940	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACGSH8M1_004970	COG3039	Transposase
ACGSH8M1_005020	COG0084	hydrolase, TatD family'
ACGSH8M1_005030	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ACGSH8M1_005050	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ACGSH8M1_005060	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ACGSH8M1_005070	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ACGSH8M1_005080	COG0813	purine-nucleoside phosphorylase activity
ACGSH8M1_005090	COG5002	protein histidine kinase activity
ACGSH8M1_005090	COG5001	Diguanylate cyclase
ACGSH8M1_005090	COG3447	MASE1 domain protein
ACGSH8M1_005110	COG0560	Phosphoserine phosphatase
ACGSH8M1_005140	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ACGSH8M1_005160	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
ACGSH8M1_005170	COG0776	regulation of translation
ACGSH8M1_005200	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACGSH8M1_005210	COG0735	belongs to the Fur family
ACGSH8M1_005250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ACGSH8M1_005260	COG0513	Belongs to the DEAD box helicase family
ACGSH8M1_005270	COG3022	response to hydroperoxide
ACGSH8M1_005280	COG2805	Type II/IV secretion system protein
ACGSH8M1_005300	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ACGSH8M1_005310	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ACGSH8M1_005320	COG0762	integral membrane protein
ACGSH8M1_005330	COG1872	DUF167
ACGSH8M1_005370	COG3112	Uncharacterised protein family (UPF0231)
ACGSH8M1_005380	COG3835	regulator
ACGSH8M1_005390	COG2610	gluconate transmembrane transporter activity
ACGSH8M1_005400	COG1929	Belongs to the glycerate kinase type-1 family
ACGSH8M1_005430	COG0583	DNA-binding transcription factor activity
ACGSH8M1_005440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ACGSH8M1_005470	COG0347	Belongs to the P(II) protein family
ACGSH8M1_005480	COG1840	ABC-type Fe3 transport system, periplasmic component
ACGSH8M1_005500	COG3842	ATPase activity
ACGSH8M1_005510	COG2837	iron assimilation
ACGSH8M1_005520	COG1438	arginine binding
ACGSH8M1_005530	COG1126	abc transporter atp-binding protein
ACGSH8M1_005540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACGSH8M1_005550	COG4215	(ABC) transporter
ACGSH8M1_005560	COG4160	amino acid transport
ACGSH8M1_005570	COG0039	L-malate dehydrogenase activity
ACGSH8M1_005580	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ACGSH8M1_005590	COG1017	nitric oxide dioxygenase activity
ACGSH8M1_005590	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACGSH8M1_005610	COG4536	flavin adenine dinucleotide binding
ACGSH8M1_005620	COG4137	Cytochrome C assembly protein
ACGSH8M1_005630	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACGSH8M1_005640	COG0228	four-way junction DNA binding
ACGSH8M1_005650	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACGSH8M1_005660	COG0336	Belongs to the RNA methyltransferase TrmD family
ACGSH8M1_005670	COG0335	large ribosomal subunit rRNA binding
ACGSH8M1_005710	COG1051	belongs to the nudix hydrolase family
ACGSH8M1_005730	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ACGSH8M1_005740	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ACGSH8M1_005750	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ACGSH8M1_005770	COG0583	DNA-binding transcription factor activity
ACGSH8M1_005780	COG0640	Transcriptional regulator
ACGSH8M1_005790	COG0268	Binds directly to 16S ribosomal RNA
ACGSH8M1_005800	COG0728	peptidoglycan biosynthetic process
ACGSH8M1_005810	COG0196	riboflavin kinase activity
ACGSH8M1_005820	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACGSH8M1_005830	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ACGSH8M1_005840	COG1047	Peptidyl-prolyl cis-trans
ACGSH8M1_005850	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ACGSH8M1_005860	COG4968	Prepilin-type N-terminal cleavage methylation domain
ACGSH8M1_005930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACGSH8M1_005930	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ACGSH8M1_005960	COG1854	S-ribosylhomocysteine lyase activity
ACGSH8M1_005970	COG3385	transposase activity
ACGSH8M1_005980	COG3706	GGDEF domain
ACGSH8M1_005990	COG0557	exoribonuclease II activity
ACGSH8M1_006000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACGSH8M1_006020	COG2153	protein acetylation
ACGSH8M1_006040	COG1914	H( )-stimulated, divalent metal cation uptake system
ACGSH8M1_006050	COG0360	Binds together with S18 to 16S ribosomal RNA
ACGSH8M1_006060	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ACGSH8M1_006070	COG0359	binds to the 23S rRNA
ACGSH8M1_006150	COG1238	metal cluster binding
ACGSH8M1_006160	COG0612	Peptidase, M16
ACGSH8M1_006170	COG2918	glutathione biosynthetic process
ACGSH8M1_006180	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ACGSH8M1_006190	COG1027	Aspartate ammonia-lyase
ACGSH8M1_006200	COG3030	protein affecting phage T7 exclusion by the F plasmid
ACGSH8M1_006220	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ACGSH8M1_006230	COG0459	protein refolding
ACGSH8M1_006270	COG0564	pseudouridine synthase activity
ACGSH8M1_006280	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ACGSH8M1_006290	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ACGSH8M1_006310	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ACGSH8M1_006320	COG4208	sulfate ABC transporter
ACGSH8M1_006330	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ACGSH8M1_006340	COG0583	DNA-binding transcription factor activity
ACGSH8M1_006350	COG3397	chitin binding
ACGSH8M1_006360	COG0840	transmembrane signaling receptor activity
ACGSH8M1_006410	COG1328	CTP reductase activity
ACGSH8M1_006420	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ACGSH8M1_006450	COG1448	Aminotransferase
ACGSH8M1_006460	COG2194	sulfuric ester hydrolase activity
ACGSH8M1_006500	COG1215	transferase activity, transferring glycosyl groups
ACGSH8M1_006510	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ACGSH8M1_006520	COG3118	belongs to the thioredoxin family
ACGSH8M1_006520	COG0457	Tetratricopeptide repeat
ACGSH8M1_006590	COG0513	Belongs to the DEAD box helicase family
ACGSH8M1_006600	COG0840	transmembrane signaling receptor activity
ACGSH8M1_006620	COG4166	transmembrane transport
ACGSH8M1_006650	COG1024	Enoyl-CoA hydratase
ACGSH8M1_006680	COG4221	oxidoreductase activity
ACGSH8M1_006690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACGSH8M1_006700	COG0442	prolyl-tRNA aminoacylation
ACGSH8M1_006710	COG0840	transmembrane signaling receptor activity
ACGSH8M1_006720	COG0632	four-way junction helicase activity
ACGSH8M1_006730	COG2255	four-way junction helicase activity
ACGSH8M1_006750	COG1271	oxidase subunit
ACGSH8M1_006760	COG1294	oxidase, subunit
ACGSH8M1_006770	COG4890	Cyd operon protein YbgT
ACGSH8M1_006780	COG3790	cyd operon protein YbgE
ACGSH8M1_006790	COG0824	Thioesterase
ACGSH8M1_006800	COG0811	peptide transport
ACGSH8M1_006830	COG0823	Involved in the tonB-independent uptake of proteins
ACGSH8M1_006840	COG2885	chlorophyll binding
ACGSH8M1_006850	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ACGSH8M1_006860	COG0840	transmembrane signaling receptor activity
ACGSH8M1_006870	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ACGSH8M1_006890	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ACGSH8M1_006900	COG1640	4-alpha-glucanotransferase
ACGSH8M1_006910	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ACGSH8M1_006970	COG2130	NADP-dependent
ACGSH8M1_006980	COG1846	Transcriptional regulator
ACGSH8M1_007010	COG1522	sequence-specific DNA binding
ACGSH8M1_007040	COG0561	phosphatase activity
ACGSH8M1_007070	COG0733	neurotransmitter:sodium symporter activity
ACGSH8M1_007080	COG0733	neurotransmitter:sodium symporter activity
ACGSH8M1_007110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACGSH8M1_007140	COG1794	racemase activity, acting on amino acids and derivatives
ACGSH8M1_007160	COG1022	Amp-dependent synthetase and ligase
ACGSH8M1_007180	COG0456	acetyltransferase
ACGSH8M1_007210	COG2425	protein containing a von Willebrand factor type A (vWA) domain
ACGSH8M1_007220	COG5002	protein histidine kinase activity
ACGSH8M1_007220	COG5001	Diguanylate cyclase
ACGSH8M1_007230	COG0745	RESPONSE REGULATOR receiver
ACGSH8M1_007230	COG3706	GGDEF domain
ACGSH8M1_007260	COG0456	acetyltransferase
ACGSH8M1_007280	COG0456	acetyltransferase
ACGSH8M1_007290	COG1902	pentaerythritol trinitrate reductase activity
ACGSH8M1_007310	COG2852	Protein conserved in bacteria
ACGSH8M1_007330	COG2957	Belongs to the agmatine deiminase family
ACGSH8M1_007340	COG0154	amidase activity
ACGSH8M1_007410	COG1917	Cupin 2, conserved barrel domain protein
ACGSH8M1_007410	COG2207	Transcriptional regulator
ACGSH8M1_007430	COG0513	Belongs to the DEAD box helicase family
ACGSH8M1_007440	COG2203	Gaf domain
ACGSH8M1_007440	COG2199	diguanylate cyclase activity
ACGSH8M1_007520	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
ACGSH8M1_007540	COG0577	efflux transmembrane transporter activity
ACGSH8M1_007540	COG1136	(ABC) transporter
ACGSH8M1_007550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACGSH8M1_007560	COG0745	RESPONSE REGULATOR receiver
ACGSH8M1_007570	COG2205	protein histidine kinase activity
ACGSH8M1_007630	COG1280	lysine exporter protein (LysE YggA)
ACGSH8M1_007660	COG3311	Transcriptional regulator
ACGSH8M1_007740	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
ACGSH8M1_007760	COG5377	YqaJ viral recombinase family
ACGSH8M1_007830	COG2003	Belongs to the UPF0758 family
ACGSH8M1_007930	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ACGSH8M1_007950	COG0732	type I restriction modification DNA specificity domain
ACGSH8M1_007980	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ACGSH8M1_008040	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ACGSH8M1_008050	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACGSH8M1_008070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACGSH8M1_008130	COG0745	RESPONSE REGULATOR receiver
ACGSH8M1_008140	COG3104	oligopeptide transport
ACGSH8M1_008150	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ACGSH8M1_008160	COG1555	photosystem II stabilization
ACGSH8M1_008180	COG2350	Protein conserved in bacteria
ACGSH8M1_008190	COG2917	probably involved in intracellular septation
ACGSH8M1_008200	COG0076	glutamate decarboxylase activity
ACGSH8M1_008210	COG1272	protein, Hemolysin III
ACGSH8M1_008220	COG0569	domain protein
ACGSH8M1_008220	COG2985	domain, Protein
ACGSH8M1_008240	COG0477	Major facilitator Superfamily
ACGSH8M1_008250	COG0583	DNA-binding transcription factor activity
ACGSH8M1_008260	COG3227	Zinc metalloprotease (Elastase)
ACGSH8M1_008270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACGSH8M1_008280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACGSH8M1_008300	COG2731	YhcH YjgK YiaL family protein
ACGSH8M1_008320	COG0668	transmembrane transport
ACGSH8M1_008340	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACGSH8M1_008380	COG0789	Transcriptional regulator
ACGSH8M1_008490	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ACGSH8M1_008510	COG0488	(ABC) transporter
ACGSH8M1_008520	COG0516	GMP reductase activity
ACGSH8M1_008520	COG0517	IMP dehydrogenase activity
ACGSH8M1_008540	COG0784	Response regulator, receiver
ACGSH8M1_008540	COG0835	chemotaxis
ACGSH8M1_008560	COG2755	lipolytic protein G-D-S-L family
ACGSH8M1_008570	COG4181	ATPase activity
ACGSH8M1_008580	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ACGSH8M1_008590	COG1090	epimerase
ACGSH8M1_008600	COG2200	EAL domain
ACGSH8M1_008610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACGSH8M1_008620	COG2234	aminopeptidase activity
ACGSH8M1_008620	COG4935	Belongs to the peptidase S8 family
ACGSH8M1_008630	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ACGSH8M1_008640	COG3171	Protein conserved in bacteria
ACGSH8M1_008650	COG2066	Belongs to the glutaminase family
ACGSH8M1_008660	COG2897	thiosulfate sulfurtransferase activity
ACGSH8M1_008680	COG1132	(ABC) transporter
ACGSH8M1_008720	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
ACGSH8M1_008730	COG5001	Diguanylate cyclase
ACGSH8M1_008730	COG3300	MHYT domain
ACGSH8M1_008770	COG4628	conserved protein (DUF2132)
ACGSH8M1_008780	COG0688	phosphatidylethanolamine metabolic process
ACGSH8M1_008790	COG1162	GTPase activity
ACGSH8M1_008800	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ACGSH8M1_008810	COG1278	Cold shock
ACGSH8M1_008830	COG0840	transmembrane signaling receptor activity
ACGSH8M1_008840	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACGSH8M1_008890	COG0848	biopolymer transport protein
ACGSH8M1_008900	COG0811	peptide transport
ACGSH8M1_008910	COG0811	peptide transport
ACGSH8M1_008930	COG4206	TonB-dependent receptor
ACGSH8M1_008940	COG4174	ABC transporter (Permease)
ACGSH8M1_008950	COG4239	(ABC) transporter, permease
ACGSH8M1_008970	COG0444	Belongs to the ABC transporter superfamily
ACGSH8M1_008980	COG4608	Belongs to the ABC transporter superfamily
ACGSH8M1_009000	COG2195	Cleaves the N-terminal amino acid of tripeptides
ACGSH8M1_009020	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ACGSH8M1_009060	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ACGSH8M1_009130	COG0243	molybdopterin cofactor binding
ACGSH8M1_009140	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACGSH8M1_009140	COG1648	precorrin-2 dehydrogenase activity
ACGSH8M1_009160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACGSH8M1_009160	COG1116	anion transmembrane transporter activity
ACGSH8M1_009170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACGSH8M1_009180	COG1116	anion transmembrane transporter activity
ACGSH8M1_009190	COG2146	nitrite reductase [NAD(P)H] activity
ACGSH8M1_009190	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACGSH8M1_009200	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACGSH8M1_009200	COG2146	nitrite reductase [NAD(P)H] activity
ACGSH8M1_009210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACGSH8M1_009220	COG2313	pseudouridylate synthase activity
ACGSH8M1_009270	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACGSH8M1_009290	COG2966	Psort location CytoplasmicMembrane, score
ACGSH8M1_009330	COG4175	Glycine betaine
ACGSH8M1_009340	COG4176	ABC-type proline glycine betaine transport system permease component
ACGSH8M1_009350	COG2113	Glycine betaine
ACGSH8M1_009360	COG0175	sulfate reduction
ACGSH8M1_009370	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACGSH8M1_009380	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ACGSH8M1_009400	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ACGSH8M1_009410	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ACGSH8M1_009430	COG0786	glutamate:sodium symporter activity
ACGSH8M1_009440	COG0252	asparaginase activity
ACGSH8M1_009450	COG3139	Protein of unknown function (DUF1315)
ACGSH8M1_009490	COG0616	signal peptide processing
ACGSH8M1_009500	COG1902	pentaerythritol trinitrate reductase activity
ACGSH8M1_009500	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACGSH8M1_009510	COG0778	Nitroreductase
ACGSH8M1_009530	COG0110	maltose O-acetyltransferase activity
ACGSH8M1_009540	COG2264	protein methyltransferase activity
ACGSH8M1_009550	COG0604	alcohol dehydrogenase
ACGSH8M1_009560	COG0583	DNA-binding transcription factor activity
ACGSH8M1_009570	COG2190	(PTS) system
ACGSH8M1_009570	COG1263	PTS System
ACGSH8M1_009570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACGSH8M1_009580	COG4145	pantothenate transmembrane transporter activity
ACGSH8M1_009590	COG3924	membrane
ACGSH8M1_009600	COG0439	Biotin carboxylase
ACGSH8M1_009610	COG0511	ligase activity, forming carbon-carbon bonds
ACGSH8M1_009620	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ACGSH8M1_009630	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACGSH8M1_009660	COG3381	protein complex oligomerization
ACGSH8M1_009680	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACGSH8M1_009700	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ACGSH8M1_009710	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACGSH8M1_009710	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACGSH8M1_009740	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ACGSH8M1_009750	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACGSH8M1_009760	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ACGSH8M1_009770	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ACGSH8M1_009780	COG4172	Belongs to the ABC transporter superfamily
ACGSH8M1_009820	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ACGSH8M1_009830	COG0142	geranyltranstransferase activity
ACGSH8M1_009840	COG1722	exodeoxyribonuclease VII activity
ACGSH8M1_009850	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ACGSH8M1_009860	COG1360	Flagellar Motor Protein
ACGSH8M1_009870	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACGSH8M1_009890	COG1534	Rna-binding protein
ACGSH8M1_009900	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ACGSH8M1_009910	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACGSH8M1_009920	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACGSH8M1_009930	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACGSH8M1_009940	COG0149	triose-phosphate isomerase activity
ACGSH8M1_009950	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ACGSH8M1_009960	COG0779	Required for maturation of 30S ribosomal subunits
ACGSH8M1_009970	COG0195	Participates in both transcription termination and antitermination
ACGSH8M1_009980	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ACGSH8M1_009990	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ACGSH8M1_010000	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ACGSH8M1_010010	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ACGSH8M1_010020	COG1185	polyribonucleotide nucleotidyltransferase activity
ACGSH8M1_010030	COG2211	Major facilitator Superfamily
ACGSH8M1_010040	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ACGSH8M1_010050	COG1422	Protein of unknown function (DUF1090)
ACGSH8M1_010060	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACGSH8M1_010080	COG3039	Transposase
ACGSH8M1_010090	COG3039	Transposase
ACGSH8M1_010110	COG4372	Transposase
ACGSH8M1_010120	COG4804	nuclease activity
ACGSH8M1_010160	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ACGSH8M1_010230	COG2194	sulfuric ester hydrolase activity
ACGSH8M1_010250	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ACGSH8M1_010280	COG1484	DNA-dependent DNA replication
ACGSH8M1_010290	COG4584	PFAM Integrase catalytic
ACGSH8M1_010300	COG4974	Belongs to the 'phage' integrase family
ACGSH8M1_010310	COG5001	Diguanylate cyclase
ACGSH8M1_010310	COG3447	MASE1 domain protein
ACGSH8M1_010310	COG5002	protein histidine kinase activity
ACGSH8M1_010320	COG5433	transposase activity
ACGSH8M1_010450	COG0312	modulator of DNA gyrase
ACGSH8M1_010470	COG0312	modulator of DNA gyrase
ACGSH8M1_010490	COG0716	FMN binding
ACGSH8M1_010500	COG4974	Belongs to the 'phage' integrase family
ACGSH8M1_010510	COG1970	mechanosensitive ion channel activity
ACGSH8M1_010540	COG0789	Transcriptional regulator
ACGSH8M1_010570	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ACGSH8M1_010590	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACGSH8M1_010610	COG0321	lipoyl(octanoyl) transferase activity
ACGSH8M1_010620	COG2921	Belongs to the UPF0250 family
ACGSH8M1_010630	COG1686	Belongs to the peptidase S11 family
ACGSH8M1_010640	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ACGSH8M1_010650	COG2951	lytic endotransglycosylase activity
ACGSH8M1_010660	COG0772	Belongs to the SEDS family
ACGSH8M1_010670	COG0768	penicillin binding
ACGSH8M1_010680	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ACGSH8M1_010690	COG0799	negative regulation of ribosome biogenesis
ACGSH8M1_010700	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ACGSH8M1_010740	COG0495	leucyl-tRNA aminoacylation
ACGSH8M1_010750	COG2888	peptidyl-tyrosine sulfation
ACGSH8M1_010760	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ACGSH8M1_010770	COG4535	Mg2 and Co2 transporter CorC
ACGSH8M1_010780	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ACGSH8M1_010790	COG1702	phosphate starvation-inducible protein PhoH
ACGSH8M1_010800	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACGSH8M1_010810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACGSH8M1_010820	COG1335	isochorismatase
ACGSH8M1_010830	COG1278	Cold shock
ACGSH8M1_010860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACGSH8M1_010870	COG2199	diguanylate cyclase activity
ACGSH8M1_010890	COG2199	diguanylate cyclase activity
ACGSH8M1_010910	COG3385	transposase activity
ACGSH8M1_010920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACGSH8M1_010950	COG1464	Belongs to the NlpA lipoprotein family
ACGSH8M1_010960	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACGSH8M1_010970	COG2011	ABC-type metal ion transport system permease component
ACGSH8M1_010980	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ACGSH8M1_011000	COG0516	GMP reductase activity
ACGSH8M1_011010	COG4067	protein conserved in archaea
ACGSH8M1_011010	COG0189	ligase activity
ACGSH8M1_011030	COG0745	RESPONSE REGULATOR receiver
ACGSH8M1_011050	COG0300	oxidoreductase activity
ACGSH8M1_011090	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACGSH8M1_011100	COG3214	Protein conserved in bacteria
ACGSH8M1_011130	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ACGSH8M1_011140	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ACGSH8M1_011150	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ACGSH8M1_011160	COG1053	succinate dehydrogenase
ACGSH8M1_011180	COG0584	glycerophosphoryl diester phosphodiesterase
ACGSH8M1_011190	COG1511	domain protein
ACGSH8M1_011190	COG3264	Mechanosensitive ion channel
ACGSH8M1_011210	COG0739	heme binding
ACGSH8M1_011240	COG0583	DNA-binding transcription factor activity
ACGSH8M1_011270	COG0583	DNA-binding transcription factor activity
ACGSH8M1_011280	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ACGSH8M1_011360	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ACGSH8M1_011370	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ACGSH8M1_011390	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ACGSH8M1_011400	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ACGSH8M1_011410	COG0546	phosphoglycolate phosphatase activity
ACGSH8M1_011420	COG0180	Tryptophanyl-tRNA synthetase
ACGSH8M1_011450	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACGSH8M1_011470	COG1012	belongs to the aldehyde dehydrogenase family
ACGSH8M1_011530	COG2801	Transposase and inactivated derivatives
ACGSH8M1_011540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACGSH8M1_011590	COG0490	domain, Protein
ACGSH8M1_011590	COG0471	metal ion transport
ACGSH8M1_011600	COG0012	GTP binding
ACGSH8M1_011610	COG0193	aminoacyl-tRNA hydrolase activity
ACGSH8M1_011620	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACGSH8M1_011630	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ACGSH8M1_011640	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ACGSH8M1_011650	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ACGSH8M1_011660	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ACGSH8M1_011670	COG2890	protein-(glutamine-N5) methyltransferase activity
ACGSH8M1_011690	COG2912	Transglutaminase-like superfamily
ACGSH8M1_011700	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ACGSH8M1_011710	COG1301	dicarboxylic acid transport
ACGSH8M1_011730	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ACGSH8M1_011760	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ACGSH8M1_011770	COG1115	amino acid carrier protein
ACGSH8M1_011810	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ACGSH8M1_011820	COG1678	Uncharacterized ACR, COG1678
ACGSH8M1_011830	COG0189	ligase activity
ACGSH8M1_011840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ACGSH8M1_011860	COG3091	SprT-like family
ACGSH8M1_011880	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ACGSH8M1_011900	COG2801	Transposase and inactivated derivatives
ACGSH8M1_011940	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ACGSH8M1_011960	COG0739	heme binding
ACGSH8M1_011970	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ACGSH8M1_011980	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
ACGSH8M1_011980	COG3408	Glycogen debranching enzyme
ACGSH8M1_012000	COG1881	PFAM PEBP family protein
ACGSH8M1_012020	COG0583	DNA-binding transcription factor activity
ACGSH8M1_012040	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ACGSH8M1_012060	COG0583	DNA-binding transcription factor activity
ACGSH8M1_012070	COG1028	Short-chain dehydrogenase reductase Sdr
ACGSH8M1_012080	COG0616	signal peptide processing
ACGSH8M1_012090	COG3724	N-succinylarginine dihydrolase activity
ACGSH8M1_012100	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACGSH8M1_012130	COG0840	transmembrane signaling receptor activity
ACGSH8M1_012150	COG2971	BadF BadG BcrA BcrD
ACGSH8M1_012170	COG4608	Belongs to the ABC transporter superfamily
ACGSH8M1_012180	COG0444	Belongs to the ABC transporter superfamily
ACGSH8M1_012190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACGSH8M1_012220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACGSH8M1_012240	COG0640	Transcriptional regulator
ACGSH8M1_012250	COG0798	PFAM Bile acid sodium symporter
ACGSH8M1_012260	COG1393	Belongs to the ArsC family
ACGSH8M1_012290	COG1677	Flagellar hook-basal body complex protein FliE
ACGSH8M1_012310	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACGSH8M1_012410	COG1987	bacterial-type flagellum assembly
ACGSH8M1_012430	COG1684	flagellar biosynthetic protein fliR
ACGSH8M1_012450	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACGSH8M1_012470	COG0455	bacterial-type flagellum organization
ACGSH8M1_012500	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ACGSH8M1_012510	COG0643	Histidine kinase
ACGSH8M1_012510	COG2198	Histidine kinase
ACGSH8M1_012530	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ACGSH8M1_012540	COG1360	Flagellar Motor Protein
ACGSH8M1_012550	COG1192	Involved in chromosome partitioning
ACGSH8M1_012570	COG0835	chemotaxis
ACGSH8M1_012600	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACGSH8M1_012610	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACGSH8M1_012620	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACGSH8M1_012630	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
ACGSH8M1_012640	COG1138	Cytochrome C-type biogenesis protein
ACGSH8M1_012650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACGSH8M1_012670	COG0457	Tetratricopeptide repeat
ACGSH8M1_012700	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ACGSH8M1_012710	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ACGSH8M1_012710	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACGSH8M1_012740	COG0259	pyridoxamine-phosphate oxidase activity
ACGSH8M1_012800	COG3153	acetyltransferase
ACGSH8M1_012830	COG0800	Aldolase
ACGSH8M1_012840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACGSH8M1_012860	COG2721	sulfolactate sulfo-lyase activity
ACGSH8M1_012870	COG0246	Mannitol dehydrogenase
ACGSH8M1_012940	COG3311	Transcriptional regulator
ACGSH8M1_012970	COG4251	negative regulation of phosphorylation
ACGSH8M1_012990	COG4584	PFAM Integrase catalytic
ACGSH8M1_013000	COG1484	DNA-dependent DNA replication
ACGSH8M1_013010	COG2801	Transposase and inactivated derivatives
ACGSH8M1_013020	COG2963	transposase activity
ACGSH8M1_013030	COG0582	viral genome integration into host DNA
ACGSH8M1_013040	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ACGSH8M1_013050	COG2867	negative regulation of translational initiation
ACGSH8M1_013070	COG0702	epimerase
ACGSH8M1_013080	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACGSH8M1_013090	COG1454	alcohol dehydrogenase
ACGSH8M1_013100	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ACGSH8M1_013120	COG1957	nucleoside hydrolase
ACGSH8M1_013170	COG1280	lysine exporter protein (LysE YggA)
ACGSH8M1_013190	COG3263	regulation of cellular component size
ACGSH8M1_013210	COG1876	peptidase activity
ACGSH8M1_013220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACGSH8M1_013230	COG1393	Belongs to the ArsC family
ACGSH8M1_013250	COG3069	C4-dicarboxylate transmembrane transporter activity
ACGSH8M1_013260	COG1473	amidohydrolase
ACGSH8M1_013280	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ACGSH8M1_013290	COG0017	Asparaginyl-tRNA synthetase
ACGSH8M1_013330	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACGSH8M1_013340	COG0156	8-amino-7-oxononanoate synthase activity
ACGSH8M1_013350	COG1073	alpha beta
ACGSH8M1_013350	COG2226	methyltransferase
ACGSH8M1_013360	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ACGSH8M1_013370	COG0501	Belongs to the peptidase M48B family
ACGSH8M1_013380	COG0633	Ferredoxin
ACGSH8M1_013380	COG3217	Mosc domain protein beta barrel domain protein
ACGSH8M1_013380	COG3217	Mosc domain protein beta barrel domain protein
ACGSH8M1_013380	COG0633	Ferredoxin
ACGSH8M1_013400	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ACGSH8M1_013400	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ACGSH8M1_013400	COG1013	pyruvate-flavodoxin oxidoreductase activity
ACGSH8M1_013400	COG0674	pyruvate-flavodoxin oxidoreductase activity
ACGSH8M1_013410	COG2841	Protein conserved in bacteria
ACGSH8M1_013430	COG0534	Mate efflux family protein
ACGSH8M1_013480	COG1454	alcohol dehydrogenase
ACGSH8M1_013500	COG1309	transcriptional regulator
ACGSH8M1_013530	COG0791	NLP P60 protein
ACGSH8M1_013540	COG0583	DNA-binding transcription factor activity
ACGSH8M1_013580	COG0500	methyltransferase
ACGSH8M1_013590	COG4106	trans-aconitate 2-methyltransferase activity
ACGSH8M1_013600	COG1801	Protein of unknown function DUF72
ACGSH8M1_013610	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ACGSH8M1_013620	COG0217	transcriptional regulatory protein
ACGSH8M1_013630	COG2194	sulfuric ester hydrolase activity
ACGSH8M1_013640	COG1846	Transcriptional regulator
ACGSH8M1_013640	COG1940	carbohydrate kinase activity
ACGSH8M1_013650	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ACGSH8M1_013660	COG0363	glucosamine-6-phosphate deaminase activity
ACGSH8M1_013670	COG2190	(PTS) system
ACGSH8M1_013670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACGSH8M1_013670	COG1263	PTS System
ACGSH8M1_013690	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACGSH8M1_013700	COG0735	belongs to the Fur family
ACGSH8M1_013720	COG0716	FMN binding
ACGSH8M1_013750	COG0596	Alpha beta hydrolase
ACGSH8M1_013760	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ACGSH8M1_013770	COG0033	Phosphoglucomutase
ACGSH8M1_013790	COG1846	Transcriptional regulator
ACGSH8M1_013800	COG2951	lytic endotransglycosylase activity
ACGSH8M1_013810	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ACGSH8M1_013820	COG4136	ATPase activity
ACGSH8M1_013840	COG4134	Bacterial extracellular solute-binding protein
ACGSH8M1_013860	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACGSH8M1_013880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACGSH8M1_013900	COG0729	surface antigen
ACGSH8M1_013910	COG2911	Protein conserved in bacteria
ACGSH8M1_013930	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ACGSH8M1_013950	COG0741	lytic transglycosylase activity
ACGSH8M1_013980	COG1607	acyl-coa hydrolase
ACGSH8M1_014000	COG3021	interspecies interaction between organisms
ACGSH8M1_014010	COG1388	LysM domain
ACGSH8M1_014010	COG0741	lytic transglycosylase activity
ACGSH8M1_014020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACGSH8M1_014030	COG2226	methyltransferase
ACGSH8M1_014040	COG0328	RNA-DNA hybrid ribonuclease activity
ACGSH8M1_014080	COG5433	transposase activity
ACGSH8M1_014130	COG2916	Histone family protein nucleoid-structuring protein H-NS
ACGSH8M1_014170	COG2850	peptidyl-arginine hydroxylation
ACGSH8M1_014280	COG0210	DNA helicase
ACGSH8M1_014330	COG4974	Belongs to the 'phage' integrase family
ACGSH8M1_014340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACGSH8M1_014360	COG0784	Response regulator, receiver
ACGSH8M1_014360	COG3437	response regulator, receiver
ACGSH8M1_014370	COG3437	response regulator, receiver
ACGSH8M1_014370	COG0784	Response regulator, receiver
ACGSH8M1_014380	COG1960	acyl-CoA dehydrogenase activity
ACGSH8M1_014390	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ACGSH8M1_014400	COG0121	glutamine amidotransferase
ACGSH8M1_014420	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ACGSH8M1_014440	COG2205	protein histidine kinase activity
ACGSH8M1_014440	COG0784	Response regulator, receiver
ACGSH8M1_014470	COG2197	response regulator
ACGSH8M1_014480	COG3850	Histidine kinase
ACGSH8M1_014490	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACGSH8M1_014500	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACGSH8M1_014500	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACGSH8M1_014520	COG0243	molybdopterin cofactor binding
ACGSH8M1_014530	COG0437	4 iron, 4 sulfur cluster binding
ACGSH8M1_014540	COG0348	domain, Protein
ACGSH8M1_014560	COG3005	denitrification pathway
ACGSH8M1_014570	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACGSH8M1_014580	COG0315	cyclic pyranopterin monophosphate synthase activity
ACGSH8M1_014590	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ACGSH8M1_014600	COG0314	molybdopterin synthase activity
ACGSH8M1_014630	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ACGSH8M1_014640	COG2267	carboxylic ester hydrolase activity
ACGSH8M1_014650	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ACGSH8M1_014680	COG0302	gtp cyclohydrolase
ACGSH8M1_014690	COG0840	transmembrane signaling receptor activity
ACGSH8M1_014700	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ACGSH8M1_014720	COG0583	DNA-binding transcription factor activity
ACGSH8M1_014780	COG2195	Cleaves the N-terminal amino acid of tripeptides
ACGSH8M1_014790	COG1166	arginine decarboxylase activity
ACGSH8M1_014900	COG5433	transposase activity
ACGSH8M1_014930	COG2801	Transposase and inactivated derivatives
ACGSH8M1_014940	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ACGSH8M1_014950	COG1187	pseudouridine synthase activity
ACGSH8M1_014960	COG2807	transmembrane transport
ACGSH8M1_014980	COG0583	DNA-binding transcription factor activity
ACGSH8M1_015020	COG2979	Protein of unknown function (DUF533)
ACGSH8M1_015040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACGSH8M1_015050	COG1271	oxidase subunit
ACGSH8M1_015060	COG1294	oxidase, subunit
ACGSH8M1_015080	COG2814	Major facilitator Superfamily
ACGSH8M1_015090	COG0656	L-ascorbic acid biosynthetic process
ACGSH8M1_015130	COG0583	DNA-binding transcription factor activity
ACGSH8M1_015150	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ACGSH8M1_015160	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ACGSH8M1_015170	COG2271	Major facilitator Superfamily
ACGSH8M1_015180	COG1349	DNA-binding transcription factor activity
ACGSH8M1_015200	COG0584	glycerophosphoryl diester phosphodiesterase
ACGSH8M1_015210	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACGSH8M1_015220	COG0287	Prephenate dehydrogenase
ACGSH8M1_015220	COG1605	Chorismate mutase
ACGSH8M1_015240	COG3085	chromosome segregation
ACGSH8M1_015250	COG4574	serine-type endopeptidase inhibitor activity
ACGSH8M1_015280	COG0675	Transposase, IS605 OrfB family
ACGSH8M1_015300	COG4771	TonB-dependent receptor
ACGSH8M1_015310	COG3083	sulfuric ester hydrolase activity
ACGSH8M1_015320	COG3082	Protein of unknown function (DUF1414)
ACGSH8M1_015330	COG3081	Nucleoid-associated protein
ACGSH8M1_015350	COG1175	transmembrane transport
ACGSH8M1_015370	COG3842	ATPase activity
ACGSH8M1_015390	COG0596	Alpha beta hydrolase
ACGSH8M1_015420	COG0425	Belongs to the sulfur carrier protein TusA family
ACGSH8M1_015430	COG4783	chaperone-mediated protein folding
ACGSH8M1_015450	COG1393	Belongs to the ArsC family
ACGSH8M1_015500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACGSH8M1_015510	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ACGSH8M1_015520	COG2431	L-lysine efflux transmembrane transporter activity
ACGSH8M1_015540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACGSH8M1_015550	COG4215	(ABC) transporter
ACGSH8M1_015560	COG4160	amino acid transport
ACGSH8M1_015580	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ACGSH8M1_015600	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACGSH8M1_015610	COG2373	Large extracellular alpha-helical protein
ACGSH8M1_015620	COG4953	penicillin-binding protein 1C
ACGSH8M1_015640	COG0301	tRNA thio-modification
ACGSH8M1_015640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACGSH8M1_015670	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACGSH8M1_015680	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACGSH8M1_015690	COG1334	flagellar protein FlaG
ACGSH8M1_015760	COG2089	acid synthase
ACGSH8M1_015780	COG1083	cytidylyl-transferase
ACGSH8M1_015790	COG3039	Transposase
ACGSH8M1_015820	COG1028	Short-chain dehydrogenase reductase Sdr
ACGSH8M1_015830	COG0318	PFAM AMP-dependent synthetase and ligase
ACGSH8M1_015860	COG1216	Glycosyl transferase, family 2
ACGSH8M1_015880	COG0562	UDP-galactopyranose mutase
ACGSH8M1_015900	COG0438	transferase activity, transferring glycosyl groups
ACGSH8M1_015970	COG5433	transposase activity
ACGSH8M1_015980	COG0438	transferase activity, transferring glycosyl groups
ACGSH8M1_015990	COG0297	glycogen (starch) synthase activity
ACGSH8M1_016030	COG0529	Catalyzes the synthesis of activated sulfate
ACGSH8M1_016050	COG0574	Belongs to the PEP-utilizing enzyme family
ACGSH8M1_016050	COG3848	Pyruvate phosphate dikinase
ACGSH8M1_016060	COG0512	Glutamine amidotransferase of anthranilate synthase
ACGSH8M1_016060	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACGSH8M1_016070	COG1213	nucleotidyl transferase
ACGSH8M1_016080	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACGSH8M1_016090	COG1086	Polysaccharide biosynthesis protein
ACGSH8M1_016100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ACGSH8M1_016120	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ACGSH8M1_016180	COG0346	lactoylglutathione lyase activity
ACGSH8M1_016190	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACGSH8M1_016210	COG4659	FMN binding
ACGSH8M1_016220	COG4658	electron transport chain
ACGSH8M1_016240	COG2878	Part of a membrane complex involved in electron transport
ACGSH8M1_016250	COG4657	Part of a membrane complex involved in electron transport
ACGSH8M1_016260	COG0697	spore germination
ACGSH8M1_016300	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ACGSH8M1_016310	COG1288	antiporter activity
ACGSH8M1_016320	COG0436	Aminotransferase
ACGSH8M1_016340	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ACGSH8M1_016350	COG2027	D-alanyl-D-alanine carboxypeptidase
ACGSH8M1_016360	COG1061	Type III restriction enzyme res subunit
ACGSH8M1_016370	COG1566	PFAM secretion protein HlyD family protein
ACGSH8M1_016400	COG0675	Transposase, IS605 OrfB family
ACGSH8M1_016420	COG3264	Mechanosensitive ion channel
ACGSH8M1_016420	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ACGSH8M1_016430	COG1966	Carbon starvation protein
ACGSH8M1_016440	COG3279	Response regulator of the LytR AlgR family
ACGSH8M1_016450	COG3275	phosphorelay sensor kinase activity
ACGSH8M1_016470	COG1012	belongs to the aldehyde dehydrogenase family
ACGSH8M1_016470	COG1454	alcohol dehydrogenase
ACGSH8M1_016480	COG2095	MarC family integral membrane protein
ACGSH8M1_016500	COG0601	transmembrane transport
ACGSH8M1_016510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACGSH8M1_016520	COG0444	Belongs to the ABC transporter superfamily
ACGSH8M1_016540	COG0861	Integral membrane protein TerC family
ACGSH8M1_016550	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ACGSH8M1_016570	COG1301	dicarboxylic acid transport
ACGSH8M1_016600	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ACGSH8M1_016630	COG0537	adenosine 5'-monophosphoramidase activity
ACGSH8M1_016700	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACGSH8M1_016720	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACGSH8M1_016750	COG2354	Protein conserved in bacteria
ACGSH8M1_016760	COG1164	Oligoendopeptidase f
ACGSH8M1_016770	COG1164	Oligoendopeptidase f
ACGSH8M1_016790	COG1252	NADH dehydrogenase
ACGSH8M1_016800	COG0393	Putative heavy-metal-binding
ACGSH8M1_016810	COG1368	sulfuric ester hydrolase activity
ACGSH8M1_016830	COG0527	aspartate kinase activity
ACGSH8M1_016850	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ACGSH8M1_016850	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ACGSH8M1_016860	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACGSH8M1_016910	COG0583	DNA-binding transcription factor activity
ACGSH8M1_016920	COG1620	l-lactate permease
ACGSH8M1_016930	COG0247	lactate metabolic process
ACGSH8M1_016940	COG1139	Iron-sulfur cluster binding protein
ACGSH8M1_017040	COG1136	(ABC) transporter
ACGSH8M1_017080	COG2814	Major facilitator Superfamily
ACGSH8M1_017130	COG0672	)-iron permease
ACGSH8M1_017200	COG2308	Evidence 4 Homologs of previously reported genes of
ACGSH8M1_017220	COG2801	Transposase and inactivated derivatives
ACGSH8M1_017240	COG0659	secondary active sulfate transmembrane transporter activity
ACGSH8M1_017270	COG4974	Belongs to the 'phage' integrase family
ACGSH8M1_017300	COG2801	Transposase and inactivated derivatives
ACGSH8M1_017320	COG4584	PFAM Integrase catalytic
ACGSH8M1_017330	COG1484	DNA-dependent DNA replication
ACGSH8M1_017410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ACGSH8M1_017420	COG3039	Transposase
ACGSH8M1_017430	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ACGSH8M1_017450	COG0326	Molecular chaperone. Has ATPase activity
ACGSH8M1_017460	COG0563	adenylate kinase activity
ACGSH8M1_017470	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ACGSH8M1_017480	COG3788	relative of glutathione S-transferase, MAPEG superfamily
ACGSH8M1_017490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACGSH8M1_017500	COG0840	transmembrane signaling receptor activity
ACGSH8M1_017530	COG3300	MHYT domain
ACGSH8M1_017530	COG5001	Diguanylate cyclase
ACGSH8M1_017540	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ACGSH8M1_017580	COG1021	2,3-dihydroxybenzoate-AMP ligase
ACGSH8M1_017590	COG1535	isochorismatase
ACGSH8M1_017590	COG3433	isochorismatase activity
ACGSH8M1_017600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACGSH8M1_017610	COG1028	Short-chain dehydrogenase reductase Sdr
ACGSH8M1_017630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACGSH8M1_017660	COG1120	ATPase activity
ACGSH8M1_017670	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACGSH8M1_017680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACGSH8M1_017690	COG4771	TonB-dependent receptor
ACGSH8M1_017730	COG0598	Magnesium transport protein CorA
ACGSH8M1_017770	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ACGSH8M1_017780	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ACGSH8M1_017790	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACGSH8M1_017800	COG0861	Integral membrane protein TerC family
ACGSH8M1_017830	COG1022	Amp-dependent synthetase and ligase
ACGSH8M1_017840	COG0295	cytidine deaminase activity
ACGSH8M1_017850	COG1346	cytolysis
ACGSH8M1_017860	COG1380	Effector of murein hydrolase LrgA
ACGSH8M1_017870	COG3345	alpha-galactosidase
ACGSH8M1_017890	COG2925	Exonuclease
ACGSH8M1_017900	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ACGSH8M1_017910	COG0392	lysyltransferase activity
ACGSH8M1_017910	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ACGSH8M1_017940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACGSH8M1_017950	COG0436	Aminotransferase
ACGSH8M1_017960	COG0583	DNA-binding transcription factor activity
ACGSH8M1_017970	COG2160	L-arabinose isomerase activity
ACGSH8M1_017990	COG1069	ribulokinase activity
ACGSH8M1_018000	COG1879	ABC-type sugar transport system periplasmic component
ACGSH8M1_018020	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACGSH8M1_018040	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ACGSH8M1_018050	COG0254	rRNA binding
ACGSH8M1_018080	COG1451	nucleotide metabolic process
ACGSH8M1_018110	COG3069	C4-dicarboxylate transmembrane transporter activity
ACGSH8M1_018130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACGSH8M1_018130	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ACGSH8M1_018140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACGSH8M1_018180	COG2009	succinate dehydrogenase
ACGSH8M1_018190	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ACGSH8M1_018220	COG0567	Dehydrogenase, E1 component
ACGSH8M1_018230	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACGSH8M1_018240	COG0045	succinate-CoA ligase (ADP-forming) activity
ACGSH8M1_018250	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ACGSH8M1_018260	COG2801	Transposase and inactivated derivatives
ACGSH8M1_018270	COG4584	PFAM Integrase catalytic
ACGSH8M1_018280	COG1484	DNA-dependent DNA replication
ACGSH8M1_018340	COG2801	Transposase and inactivated derivatives
ACGSH8M1_018350	COG2963	transposase activity
ACGSH8M1_018360	COG2983	Belongs to the UPF0260 family
ACGSH8M1_018370	COG1882	Formate acetyltransferase
ACGSH8M1_018380	COG2116	formate transmembrane transporter activity
ACGSH8M1_018390	COG1944	ATP diphosphatase activity
ACGSH8M1_018420	COG2076	Multidrug Resistance protein
ACGSH8M1_018430	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ACGSH8M1_018440	COG1278	Cold shock
ACGSH8M1_018450	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ACGSH8M1_018460	COG0542	response to heat
ACGSH8M1_018470	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ACGSH8M1_018480	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ACGSH8M1_018490	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ACGSH8M1_018500	COG3134	Outer membrane lipoprotein
ACGSH8M1_018510	COG3706	GGDEF domain
ACGSH8M1_018520	COG0492	ferredoxin-NADP+ reductase activity
ACGSH8M1_018530	COG0686	Belongs to the AlaDH PNT family
ACGSH8M1_018550	COG1674	ftsk spoiiie
ACGSH8M1_018550	COG0531	amino acid
ACGSH8M1_018560	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ACGSH8M1_018570	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ACGSH8M1_018580	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ACGSH8M1_018590	COG1286	toxin biosynthetic process
ACGSH8M1_018600	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ACGSH8M1_018610	COG2723	6-phospho-beta-galactosidase activity
ACGSH8M1_018620	COG2723	6-phospho-beta-galactosidase activity
ACGSH8M1_018630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACGSH8M1_018630	COG1263	PTS System
ACGSH8M1_018640	COG1609	Transcriptional regulator
ACGSH8M1_018650	COG1609	Transcriptional regulator
ACGSH8M1_018680	COG4172	Belongs to the ABC transporter superfamily
ACGSH8M1_018710	COG4171	peptide transport system, permease
ACGSH8M1_018720	COG4168	peptide transport system, permease
ACGSH8M1_018750	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ACGSH8M1_018760	COG1842	Phage shock protein A
ACGSH8M1_018800	COG3106	COG3106 Predicted ATPase
ACGSH8M1_018810	COG3768	UPF0283 membrane protein
ACGSH8M1_018830	COG2154	pterin-4-alpha-carbinolamine dehydratase
ACGSH8M1_018860	COG2199	diguanylate cyclase activity
ACGSH8M1_018870	COG2885	chlorophyll binding
ACGSH8M1_018920	COG0366	Alpha amylase catalytic
ACGSH8M1_018920	COG1874	Beta-galactosidase
ACGSH8M1_018940	COG0675	Transposase, IS605 OrfB family
ACGSH8M1_018970	COG0517	IMP dehydrogenase activity
ACGSH8M1_018970	COG0516	GMP reductase activity
ACGSH8M1_018980	COG0519	Catalyzes the synthesis of GMP from XMP
ACGSH8M1_018980	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACGSH8M1_019030	COG1846	Transcriptional regulator
ACGSH8M1_019070	COG2062	phosphohistidine phosphatase, SixA
ACGSH8M1_019090	COG0697	spore germination
ACGSH8M1_019110	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ACGSH8M1_019120	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ACGSH8M1_019140	COG4591	ABC-type transport system involved in lipoprotein release permease component
ACGSH8M1_019150	COG1136	(ABC) transporter
ACGSH8M1_019160	COG4591	ABC-type transport system involved in lipoprotein release permease component
ACGSH8M1_019170	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ACGSH8M1_019190	COG0544	peptidyl-prolyl cis-trans isomerase activity
ACGSH8M1_019200	COG0740	serine-type endopeptidase activity
ACGSH8M1_019210	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ACGSH8M1_019220	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ACGSH8M1_019230	COG0776	regulation of translation
ACGSH8M1_019240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACGSH8M1_019250	COG0488	(ABC) transporter
ACGSH8M1_019260	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACGSH8M1_019270	COG3162	membrane
ACGSH8M1_019300	COG1024	Enoyl-CoA hydratase
ACGSH8M1_019310	COG1115	amino acid carrier protein
ACGSH8M1_019330	COG3228	Belongs to the MtfA family
ACGSH8M1_019340	COG1584	GPR1 FUN34 yaaH family protein
ACGSH8M1_019400	COG1024	Enoyl-CoA hydratase
ACGSH8M1_019410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACGSH8M1_019420	COG1960	acyl-CoA dehydrogenase activity
ACGSH8M1_019440	COG1960	acyl-CoA dehydrogenase activity
ACGSH8M1_019450	COG1024	Enoyl-CoA hydratase
ACGSH8M1_019460	COG1024	Enoyl-CoA hydratase
ACGSH8M1_019480	COG1028	Short-chain dehydrogenase reductase Sdr
ACGSH8M1_019500	COG0730	response to heat
ACGSH8M1_019550	COG0583	DNA-binding transcription factor activity
ACGSH8M1_019560	COG2072	flavoprotein involved in K transport
ACGSH8M1_019610	COG0531	amino acid
ACGSH8M1_019620	COG1012	belongs to the aldehyde dehydrogenase family
ACGSH8M1_019630	COG2197	response regulator
ACGSH8M1_019640	COG0784	Response regulator, receiver
ACGSH8M1_019640	COG2205	protein histidine kinase activity
ACGSH8M1_019650	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACGSH8M1_019660	COG1129	ABC transporter
ACGSH8M1_019670	COG1129	ABC transporter
ACGSH8M1_019680	COG1879	ABC-type sugar transport system periplasmic component
ACGSH8M1_019700	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ACGSH8M1_019710	COG0243	molybdopterin cofactor binding
ACGSH8M1_019720	COG0745	RESPONSE REGULATOR receiver
ACGSH8M1_019720	COG3706	GGDEF domain
ACGSH8M1_019730	COG0583	DNA-binding transcription factor activity
ACGSH8M1_019740	COG2723	6-phospho-beta-galactosidase activity
ACGSH8M1_019760	COG0583	DNA-binding transcription factor activity
ACGSH8M1_019790	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ACGSH8M1_019800	COG0673	inositol 2-dehydrogenase activity
ACGSH8M1_019810	COG0583	DNA-binding transcription factor activity
ACGSH8M1_019830	COG1560	Kdo2-lipid A biosynthetic process
ACGSH8M1_019840	COG1560	Kdo2-lipid A biosynthetic process
ACGSH8M1_019870	COG0417	DNA replication proofreading
ACGSH8M1_019880	COG0534	Mate efflux family protein
ACGSH8M1_019900	COG0307	riboflavin synthase, alpha
ACGSH8M1_019930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACGSH8M1_019940	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ACGSH8M1_019950	COG0697	spore germination
ACGSH8M1_019960	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ACGSH8M1_020010	COG2996	Protein conserved in bacteria
ACGSH8M1_020040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACGSH8M1_020060	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ACGSH8M1_020070	COG2894	cell division
ACGSH8M1_020080	COG0850	regulation of cytokinetic process
ACGSH8M1_020090	COG3100	YcgL domain-containing protein
ACGSH8M1_020100	COG2951	lytic endotransglycosylase activity
ACGSH8M1_020120	COG1760	l-serine dehydratase
ACGSH8M1_020130	COG1760	l-serine dehydratase
ACGSH8M1_020140	COG3123	guanosine phosphorylase activity
ACGSH8M1_020150	COG1301	dicarboxylic acid transport
ACGSH8M1_020180	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ACGSH8M1_020190	COG2067	long-chain fatty acid transport protein
ACGSH8M1_020200	COG2067	long-chain fatty acid transport protein
ACGSH8M1_020220	COG1595	DNA-templated transcription, initiation
ACGSH8M1_020280	COG0714	Associated with various cellular activities
ACGSH8M1_020290	COG0183	Belongs to the thiolase family
ACGSH8M1_020300	COG1024	Enoyl-CoA hydratase
ACGSH8M1_020300	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACGSH8M1_020320	COG4681	YaeQ
ACGSH8M1_020340	COG3335	DDE superfamily endonuclease
ACGSH8M1_020380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACGSH8M1_020420	COG3134	Outer membrane lipoprotein
ACGSH8M1_020450	COG0675	Transposase, IS605 OrfB family
ACGSH8M1_020460	COG0318	PFAM AMP-dependent synthetase and ligase
ACGSH8M1_020470	COG2378	regulation of single-species biofilm formation
ACGSH8M1_020490	COG0140	phosphoribosyl-ATP diphosphatase activity
ACGSH8M1_020490	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACGSH8M1_020500	COG0107	imidazoleglycerol-phosphate synthase activity
ACGSH8M1_020510	COG0784	Response regulator, receiver
ACGSH8M1_020510	COG2205	protein histidine kinase activity
ACGSH8M1_020510	COG2198	Histidine kinase
ACGSH8M1_020530	COG3437	response regulator, receiver
ACGSH8M1_020540	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ACGSH8M1_020550	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ACGSH8M1_020560	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ACGSH8M1_020560	COG0131	Imidazoleglycerol-phosphate dehydratase
ACGSH8M1_020570	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACGSH8M1_020580	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ACGSH8M1_020590	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ACGSH8M1_020610	COG1199	ATP-dependent helicase activity
ACGSH8M1_020620	COG1214	PFAM Peptidase M22, glycoprotease
ACGSH8M1_020640	COG0596	Alpha beta hydrolase
ACGSH8M1_020650	COG0318	PFAM AMP-dependent synthetase and ligase
ACGSH8M1_020680	COG0697	spore germination
ACGSH8M1_020700	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACGSH8M1_020710	COG2832	Protein of unknown function (DUF454)
ACGSH8M1_020720	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ACGSH8M1_020740	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ACGSH8M1_020750	COG0583	DNA-binding transcription factor activity
ACGSH8M1_020780	COG2197	response regulator
ACGSH8M1_020790	COG2801	Transposase and inactivated derivatives
ACGSH8M1_020800	COG2963	transposase activity
ACGSH8M1_020820	COG1643	Atp-dependent helicase
ACGSH8M1_020840	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ACGSH8M1_020870	COG0675	Transposase, IS605 OrfB family
ACGSH8M1_020890	COG3437	response regulator, receiver
ACGSH8M1_020900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACGSH8M1_020910	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
ACGSH8M1_020920	COG0709	Synthesizes selenophosphate from selenide and ATP
ACGSH8M1_020960	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ACGSH8M1_020970	COG0840	transmembrane signaling receptor activity
ACGSH8M1_020980	COG1254	Belongs to the acylphosphatase family
ACGSH8M1_021000	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACGSH8M1_021000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACGSH8M1_021010	COG0489	protein tyrosine kinase activity
ACGSH8M1_021020	COG0572	uridine kinase
ACGSH8M1_021030	COG0717	Belongs to the dCTP deaminase family
ACGSH8M1_021040	COG0306	phosphate transporter
ACGSH8M1_021050	COG1530	ribonuclease E activity
ACGSH8M1_021060	COG0564	pseudouridine synthase activity
ACGSH8M1_021090	COG1399	metal-binding, possibly nucleic acid-binding protein
ACGSH8M1_021100	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ACGSH8M1_021110	COG0416	fatty acid biosynthetic process
ACGSH8M1_021120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACGSH8M1_021140	COG1028	Short-chain dehydrogenase reductase Sdr
ACGSH8M1_021150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACGSH8M1_021160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACGSH8M1_021170	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACGSH8M1_021180	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ACGSH8M1_021190	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ACGSH8M1_021200	COG0470	DNA polymerase III
ACGSH8M1_021210	COG0084	hydrolase, TatD family'
ACGSH8M1_021240	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ACGSH8M1_021240	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
ACGSH8M1_021250	COG3008	intermembrane lipid transfer
ACGSH8M1_021260	COG2995	paraquat-inducible protein a
ACGSH8M1_021290	COG3141	response to X-ray
ACGSH8M1_021310	COG1067	ATP-dependent peptidase activity
ACGSH8M1_021320	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ACGSH8M1_021370	COG0116	Belongs to the methyltransferase superfamily
ACGSH8M1_021370	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ACGSH8M1_021390	COG0167	dihydroorotate dehydrogenase activity
ACGSH8M1_021400	COG2902	Dehydrogenase
ACGSH8M1_021420	COG0308	aminopeptidase N
ACGSH8M1_021440	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
ACGSH8M1_021450	COG1956	GAF domain-containing protein
ACGSH8M1_021470	COG3278	Belongs to the heme-copper respiratory oxidase family
ACGSH8M1_021500	COG2010	Cytochrome c
ACGSH8M1_021520	COG2217	Heavy metal translocating P-type atpase
ACGSH8M1_021550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACGSH8M1_021560	COG0589	response to stress
ACGSH8M1_021570	COG0037	tRNA processing
ACGSH8M1_021600	COG0675	Transposase, IS605 OrfB family
ACGSH8M1_021630	COG0625	glutathione transferase activity
ACGSH8M1_021640	COG1869	D-ribose catabolic process
ACGSH8M1_021650	COG1129	ABC transporter
ACGSH8M1_021660	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACGSH8M1_021670	COG1879	ABC-type sugar transport system periplasmic component
ACGSH8M1_021680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACGSH8M1_021690	COG1609	Transcriptional regulator
ACGSH8M1_021710	COG0675	Transposase, IS605 OrfB family
ACGSH8M1_021740	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ACGSH8M1_021780	COG0776	regulation of translation
ACGSH8M1_021790	COG0072	phenylalanine-tRNA ligase activity
ACGSH8M1_021790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACGSH8M1_021800	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ACGSH8M1_021810	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ACGSH8M1_021820	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ACGSH8M1_021830	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ACGSH8M1_021840	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ACGSH8M1_021880	COG0675	Transposase, IS605 OrfB family
ACGSH8M1_021930	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACGSH8M1_021960	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACGSH8M1_021970	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACGSH8M1_021980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACGSH8M1_021990	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ACGSH8M1_022000	COG3313	Fe-S protein
ACGSH8M1_022010	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ACGSH8M1_022010	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACGSH8M1_022010	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACGSH8M1_022020	COG1105	Belongs to the carbohydrate kinase PfkB family
ACGSH8M1_022030	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACGSH8M1_022030	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACGSH8M1_022040	COG1609	Transcriptional regulator
ACGSH8M1_022050	COG0814	amino acid
ACGSH8M1_022070	COG5654	RES domain protein
ACGSH8M1_022080	COG0513	Belongs to the DEAD box helicase family
ACGSH8M1_022100	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ACGSH8M1_022110	COG2890	protein-(glutamine-N5) methyltransferase activity
ACGSH8M1_022120	COG2840	Smr protein MutS2
ACGSH8M1_022190	COG2824	Alkylphosphonate utilization operon protein PhnA
ACGSH8M1_022220	COG1280	lysine exporter protein (LysE YggA)
ACGSH8M1_022260	COG0675	Transposase, IS605 OrfB family
ACGSH8M1_022280	COG0588	phosphoglycerate mutase activity
ACGSH8M1_022330	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ACGSH8M1_022340	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
ACGSH8M1_022360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACGSH8M1_022370	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ACGSH8M1_022390	COG0205	6-phosphofructokinase activity
ACGSH8M1_022400	COG1473	amidohydrolase
ACGSH8M1_022410	COG1011	Hydrolase
ACGSH8M1_022420	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACGSH8M1_022440	COG3593	DNA synthesis involved in DNA repair
ACGSH8M1_022470	COG0583	DNA-binding transcription factor activity
ACGSH8M1_022480	COG0730	response to heat
ACGSH8M1_022510	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACGSH8M1_022530	COG0386	Belongs to the glutathione peroxidase family
ACGSH8M1_022540	COG0513	Belongs to the DEAD box helicase family
ACGSH8M1_022570	COG1742	UPF0060 membrane protein
ACGSH8M1_022620	COG2329	Antibiotic biosynthesis monooxygenase
ACGSH8M1_022630	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ACGSH8M1_022680	COG3243	poly(R)-hydroxyalkanoic acid synthase
ACGSH8M1_022700	COG2501	S4 domain
ACGSH8M1_022730	COG1132	(ABC) transporter
ACGSH8M1_022740	COG1132	(ABC) transporter
ACGSH8M1_022760	COG3118	belongs to the thioredoxin family
ACGSH8M1_022770	COG0471	metal ion transport
ACGSH8M1_022790	COG0058	SHG alpha-glucan phosphorylase activity
ACGSH8M1_022860	COG0814	amino acid
ACGSH8M1_022870	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ACGSH8M1_022880	COG0514	ATP-dependent DNA helicase (RecQ)
ACGSH8M1_022890	COG2766	serine protein kinase
ACGSH8M1_022900	COG2718	Belongs to the UPF0229 family
ACGSH8M1_022910	COG2719	SpoVR family
ACGSH8M1_022920	COG3385	transposase activity
ACGSH8M1_022930	COG2186	Transcriptional regulator
ACGSH8M1_022940	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ACGSH8M1_022950	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ACGSH8M1_022960	COG3385	transposase activity
ACGSH8M1_022970	COG0586	Pfam SNARE associated Golgi protein
ACGSH8M1_022990	COG0556	nucleotide-excision repair
ACGSH8M1_023020	COG2985	domain, Protein
ACGSH8M1_023020	COG0569	domain protein
ACGSH8M1_023040	COG0739	heme binding
ACGSH8M1_023040	COG0741	lytic transglycosylase activity
ACGSH8M1_023040	COG1196	nuclear chromosome segregation
ACGSH8M1_023050	COG0675	Transposase, IS605 OrfB family
ACGSH8M1_023070	COG3181	Tripartite tricarboxylate transporter family receptor
ACGSH8M1_023100	COG4565	transcriptional regulatory protein
ACGSH8M1_023110	COG3290	protein histidine kinase activity
ACGSH8M1_023120	COG1846	Transcriptional regulator
ACGSH8M1_023120	COG1940	carbohydrate kinase activity
ACGSH8M1_023130	COG0840	transmembrane signaling receptor activity
ACGSH8M1_023150	COG3012	SEC-C Motif Domain Protein
ACGSH8M1_023160	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ACGSH8M1_023170	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
ACGSH8M1_023180	COG0247	lactate metabolic process
ACGSH8M1_023200	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ACGSH8M1_023210	COG0437	4 iron, 4 sulfur cluster binding
ACGSH8M1_023220	COG3301	Polysulphide reductase, NrfD
ACGSH8M1_023230	COG1138	Cytochrome C-type biogenesis protein
ACGSH8M1_023240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACGSH8M1_023250	COG4235	cytochrome complex assembly
ACGSH8M1_023250	COG3088	subunit of a heme lyase
ACGSH8M1_023270	COG3046	protein related to deoxyribodipyrimidine photolyase
ACGSH8M1_023280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACGSH8M1_023310	COG0517	IMP dehydrogenase activity
ACGSH8M1_023310	COG0516	GMP reductase activity
ACGSH8M1_023330	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ACGSH8M1_023340	COG0583	DNA-binding transcription factor activity
ACGSH8M1_023360	COG4774	siderophore transport
ACGSH8M1_023370	COG2203	Gaf domain
ACGSH8M1_023370	COG2199	diguanylate cyclase activity
ACGSH8M1_023380	COG2200	EAL domain
ACGSH8M1_023390	COG1917	Cupin 2, conserved barrel domain protein
ACGSH8M1_023390	COG4977	sequence-specific DNA binding
ACGSH8M1_023400	COG0583	DNA-binding transcription factor activity
ACGSH8M1_023410	COG2910	NAD(P)H-binding
ACGSH8M1_023440	COG0626	cystathionine gamma-synthase activity
ACGSH8M1_023450	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ACGSH8M1_023550	COG5377	YqaJ viral recombinase family
ACGSH8M1_023610	COG3039	Transposase
ACGSH8M1_023620	COG4584	PFAM Integrase catalytic
ACGSH8M1_023630	COG1484	DNA-dependent DNA replication
ACGSH8M1_023640	COG2003	Belongs to the UPF0758 family
ACGSH8M1_023650	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ACGSH8M1_023700	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ACGSH8M1_023740	COG4804	nuclease activity
ACGSH8M1_023790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACGSH8M1_023960	COG3550	peptidyl-serine autophosphorylation
ACGSH8M1_023970	COG3335	DDE superfamily endonuclease
ACGSH8M1_023990	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ACGSH8M1_024080	COG2723	6-phospho-beta-galactosidase activity
ACGSH8M1_024090	COG2190	(PTS) system
ACGSH8M1_024090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACGSH8M1_024090	COG1263	PTS System
ACGSH8M1_024100	COG1737	Transcriptional regulator
ACGSH8M1_024140	COG1435	thymidine kinase activity
ACGSH8M1_024150	COG1757	Na H antiporter
ACGSH8M1_024160	COG2916	Histone family protein nucleoid-structuring protein H-NS
ACGSH8M1_024170	COG2096	Adenosyltransferase
ACGSH8M1_024180	COG3530	Putative quorum-sensing-regulated virulence factor
ACGSH8M1_024190	COG0602	queuosine metabolic process
ACGSH8M1_024200	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ACGSH8M1_024240	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ACGSH8M1_024260	COG0776	regulation of translation
ACGSH8M1_024270	COG0539	negative regulation of cytoplasmic translation
ACGSH8M1_024280	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ACGSH8M1_024290	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACGSH8M1_024360	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ACGSH8M1_024370	COG5001	Diguanylate cyclase
ACGSH8M1_024370	COG3300	MHYT domain
ACGSH8M1_024390	COG0583	DNA-binding transcription factor activity
ACGSH8M1_024400	COG0745	RESPONSE REGULATOR receiver
ACGSH8M1_024450	COG4989	oxidoreductase activity
ACGSH8M1_024460	COG0724	RNA recognition motif
ACGSH8M1_024480	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
ACGSH8M1_024500	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ACGSH8M1_024520	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ACGSH8M1_024530	COG1360	Flagellar Motor Protein
ACGSH8M1_024540	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACGSH8M1_024550	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACGSH8M1_024560	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACGSH8M1_024560	COG0649	NAD binding
ACGSH8M1_024590	COG1034	ATP synthesis coupled electron transport
ACGSH8M1_024600	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ACGSH8M1_024610	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACGSH8M1_024620	COG0839	Belongs to the complex I subunit 6 family
ACGSH8M1_024630	COG0713	ATP synthesis coupled electron transport
ACGSH8M1_024650	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACGSH8M1_024660	COG1007	ATP synthesis coupled electron transport
ACGSH8M1_024670	COG0047	phosphoribosylformylglycinamidine synthase activity
ACGSH8M1_024670	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACGSH8M1_024680	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ACGSH8M1_024710	COG1645	bacterial-type flagellum-dependent swarming motility
ACGSH8M1_024720	COG1160	GTP binding
ACGSH8M1_024730	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACGSH8M1_024740	COG2976	Protein conserved in bacteria
ACGSH8M1_024750	COG0124	histidyl-tRNA synthetase
ACGSH8M1_024770	COG1426	Protein conserved in bacteria
ACGSH8M1_024790	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ACGSH8M1_024800	COG0105	UTP biosynthetic process
ACGSH8M1_024830	COG0633	Ferredoxin
ACGSH8M1_024840	COG0443	Heat shock 70 kDa protein
ACGSH8M1_024850	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ACGSH8M1_024870	COG0822	iron-sulfur transferase activity
ACGSH8M1_024880	COG1104	cysteine desulfurase activity
ACGSH8M1_024950	COG2897	thiosulfate sulfurtransferase activity
ACGSH8M1_024960	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACGSH8M1_024970	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACGSH8M1_024980	COG1862	Preprotein translocase
ACGSH8M1_024990	COG0343	queuine tRNA-ribosyltransferase activity
ACGSH8M1_025000	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ACGSH8M1_025010	COG0517	IMP dehydrogenase activity
ACGSH8M1_025020	COG0450	alkyl hydroperoxide reductase
ACGSH8M1_025030	COG3634	alkyl hydroperoxide reductase activity
ACGSH8M1_025080	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACGSH8M1_025080	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACGSH8M1_025090	COG0509	glycine decarboxylation via glycine cleavage system
ACGSH8M1_025100	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ACGSH8M1_025110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACGSH8M1_025120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACGSH8M1_025150	COG2814	Major facilitator Superfamily
ACGSH8M1_025160	COG0444	Belongs to the ABC transporter superfamily
ACGSH8M1_025170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACGSH8M1_025180	COG0601	transmembrane transport
ACGSH8M1_025200	COG0625	glutathione transferase activity
ACGSH8M1_025210	COG0625	glutathione transferase activity
ACGSH8M1_025230	COG0483	inositol monophosphate 1-phosphatase activity
ACGSH8M1_025260	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACGSH8M1_025270	COG2056	Na+-H+ antiporter family
ACGSH8M1_025280	COG2814	Major facilitator Superfamily
ACGSH8M1_025290	COG0583	DNA-binding transcription factor activity
ACGSH8M1_025300	COG5001	Diguanylate cyclase
ACGSH8M1_025330	COG2050	protein possibly involved in aromatic compounds catabolism
ACGSH8M1_025350	COG0277	FAD linked oxidase domain protein
ACGSH8M1_025350	COG0247	lactate metabolic process
ACGSH8M1_025380	COG1253	flavin adenine dinucleotide binding
ACGSH8M1_025390	COG1902	pentaerythritol trinitrate reductase activity
ACGSH8M1_025410	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ACGSH8M1_025420	COG0647	UMP catabolic process
ACGSH8M1_025440	COG0367	asparagine synthase
ACGSH8M1_025470	COG0625	glutathione transferase activity
ACGSH8M1_025490	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ACGSH8M1_025520	COG0564	pseudouridine synthase activity
ACGSH8M1_025530	COG5001	Diguanylate cyclase
ACGSH8M1_025550	COG0840	transmembrane signaling receptor activity
ACGSH8M1_025560	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ACGSH8M1_025640	COG0670	Belongs to the BI1 family
ACGSH8M1_025650	COG1289	transmembrane transporter activity
ACGSH8M1_025660	COG2920	part of a sulfur-relay system
ACGSH8M1_025670	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ACGSH8M1_025680	COG0285	dihydrofolate synthase activity
ACGSH8M1_025690	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ACGSH8M1_025700	COG0101	tRNA pseudouridine synthase activity
ACGSH8M1_025720	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ACGSH8M1_025730	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACGSH8M1_025750	COG1464	Belongs to the NlpA lipoprotein family
ACGSH8M1_025800	COG1119	ATPase activity
ACGSH8M1_025810	COG0574	Belongs to the PEP-utilizing enzyme family
ACGSH8M1_025810	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACGSH8M1_025820	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ACGSH8M1_025840	COG1113	amino acid transport
ACGSH8M1_025900	COG2801	Transposase and inactivated derivatives
ACGSH8M1_025910	COG2963	transposase activity
ACGSH8M1_025940	COG5433	transposase activity
ACGSH8M1_025990	COG1242	4 iron, 4 sulfur cluster binding
ACGSH8M1_026000	COG0070	glutamate synthase
ACGSH8M1_026000	COG0067	glutamate synthase
ACGSH8M1_026000	COG0069	glutamate synthase activity
ACGSH8M1_026010	COG0493	'glutamate synthase
ACGSH8M1_026030	COG0765	amino acid transport
ACGSH8M1_026040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACGSH8M1_026080	COG4104	PAAR repeat-containing protein
ACGSH8M1_026100	COG0513	Belongs to the DEAD box helicase family
ACGSH8M1_026170	COG3706	GGDEF domain
ACGSH8M1_026180	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACGSH8M1_026190	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ACGSH8M1_026200	COG0505	Belongs to the CarA family
ACGSH8M1_026210	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ACGSH8M1_026230	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ACGSH8M1_026240	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ACGSH8M1_026250	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACGSH8M1_026260	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ACGSH8M1_026270	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACGSH8M1_026280	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
ACGSH8M1_026290	COG4139	cobalamin transport
ACGSH8M1_026340	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ACGSH8M1_026360	COG0023	Translation Initiation Factor
ACGSH8M1_026370	COG2119	membrane
ACGSH8M1_026440	COG2203	Gaf domain
ACGSH8M1_026440	COG2199	diguanylate cyclase activity
ACGSH8M1_026450	COG3039	Transposase
ACGSH8M1_026480	COG0215	cysteine-tRNA ligase activity
ACGSH8M1_026490	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACGSH8M1_026510	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACGSH8M1_026520	COG2261	transglycosylase associated protein
ACGSH8M1_026530	COG1309	transcriptional regulator
ACGSH8M1_026540	COG0604	alcohol dehydrogenase
ACGSH8M1_026560	COG0402	S-adenosylhomocysteine deaminase activity
ACGSH8M1_026570	COG0583	DNA-binding transcription factor activity
ACGSH8M1_026590	COG0322	excinuclease ABC activity
ACGSH8M1_026600	COG2197	response regulator
ACGSH8M1_026610	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ACGSH8M1_026620	COG2835	tetraacyldisaccharide 4'-kinase activity
ACGSH8M1_026630	COG1663	tetraacyldisaccharide 4'-kinase activity
ACGSH8M1_026640	COG1132	(ABC) transporter
ACGSH8M1_026650	COG0658	competence protein
ACGSH8M1_026650	COG2333	competence protein COMEC
ACGSH8M1_026680	COG0433	COG0433 Predicted ATPase
ACGSH8M1_026690	COG1448	Aminotransferase
ACGSH8M1_026720	COG5433	transposase activity
ACGSH8M1_026740	COG1199	ATP-dependent helicase activity
ACGSH8M1_026770	COG0123	including yeast histone deacetylase and acetoin utilization protein
ACGSH8M1_026780	COG0477	Major facilitator Superfamily
ACGSH8M1_026790	COG0477	Major facilitator Superfamily
ACGSH8M1_026800	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ACGSH8M1_026810	COG1785	Belongs to the alkaline phosphatase family
ACGSH8M1_026850	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACGSH8M1_026860	COG3706	GGDEF domain
ACGSH8M1_026870	COG0675	Transposase, IS605 OrfB family
ACGSH8M1_026900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACGSH8M1_026910	COG0765	amino acid transport
ACGSH8M1_026920	COG1126	abc transporter atp-binding protein
ACGSH8M1_026940	COG0531	amino acid
ACGSH8M1_026970	COG1253	flavin adenine dinucleotide binding
ACGSH8M1_026980	COG0704	Plays a role in the regulation of phosphate uptake
ACGSH8M1_027000	COG0581	inorganic phosphate transmembrane transporter activity
ACGSH8M1_027010	COG0573	inorganic phosphate transmembrane transporter activity
ACGSH8M1_027020	COG0590	tRNA wobble adenosine to inosine editing
ACGSH8M1_027040	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ACGSH8M1_027080	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ACGSH8M1_027090	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ACGSH8M1_027100	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ACGSH8M1_027110	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ACGSH8M1_027120	COG2204	response regulator
ACGSH8M1_027130	COG3852	Histidine kinase
ACGSH8M1_027140	COG2204	response regulator
ACGSH8M1_027160	COG2716	regulation of RNA biosynthetic process
ACGSH8M1_027170	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ACGSH8M1_027180	COG0248	Ppx GppA phosphatase
ACGSH8M1_027190	COG2239	Acts as a magnesium transporter
ACGSH8M1_027200	COG0675	Transposase, IS605 OrfB family
ACGSH8M1_027220	COG2239	Acts as a magnesium transporter
ACGSH8M1_027270	COG3951	Flagellar rod assembly protein muramidase FlgJ
ACGSH8M1_027270	COG1705	Flagellar rod assembly protein muramidase FlgJ
ACGSH8M1_027280	COG1706	bacterial-type flagellum-dependent cell motility
ACGSH8M1_027290	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ACGSH8M1_027300	COG4786	Flagellar basal body rod
ACGSH8M1_027320	COG4786	Flagellar basal body rod
ACGSH8M1_027340	COG1558	bacterial-type flagellum-dependent cell motility
ACGSH8M1_027350	COG1815	bacterial-type flagellum-dependent cell motility
ACGSH8M1_027360	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ACGSH8M1_027370	COG0784	Response regulator, receiver
ACGSH8M1_027370	COG0835	chemotaxis
ACGSH8M1_027380	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
ACGSH8M1_027410	COG0622	Phosphoesterase
ACGSH8M1_027420	COG0675	Transposase, IS605 OrfB family
ACGSH8M1_027450	COG4166	transmembrane transport
ACGSH8M1_027470	COG1187	pseudouridine synthase activity
ACGSH8M1_027480	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ACGSH8M1_027490	COG0675	Transposase, IS605 OrfB family
ACGSH8M1_027510	COG0697	spore germination
ACGSH8M1_027520	COG4166	transmembrane transport
ACGSH8M1_027580	COG1278	Cold shock
ACGSH8M1_027610	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ACGSH8M1_027660	COG0675	Transposase, IS605 OrfB family
ACGSH8M1_027680	COG3132	Protein of unknown function, DUF480
ACGSH8M1_027690	COG4584	PFAM Integrase catalytic
ACGSH8M1_027700	COG1484	DNA-dependent DNA replication
ACGSH8M1_027720	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACGSH8M1_027770	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACGSH8M1_027850	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACGSH8M1_027880	COG3039	Transposase
ACGSH8M1_027900	COG3039	Transposase
ACGSH8M1_027910	COG1216	Glycosyl transferase, family 2
ACGSH8M1_027980	COG1028	Short-chain dehydrogenase reductase Sdr
ACGSH8M1_027990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACGSH8M1_028000	COG1083	cytidylyl-transferase
ACGSH8M1_028050	COG1091	dTDP-4-dehydrorhamnose reductase activity
ACGSH8M1_028070	COG0745	RESPONSE REGULATOR receiver
ACGSH8M1_028100	COG3335	DDE superfamily endonuclease
ACGSH8M1_028120	COG1737	Transcriptional regulator
ACGSH8M1_028130	COG0469	pyruvate kinase activity
ACGSH8M1_028150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACGSH8M1_028160	COG1960	acyl-CoA dehydrogenase activity
ACGSH8M1_028180	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ACGSH8M1_028200	COG0583	DNA-binding transcription factor activity
ACGSH8M1_028210	COG4584	PFAM Integrase catalytic
ACGSH8M1_028220	COG1484	DNA-dependent DNA replication
ACGSH8M1_028250	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ACGSH8M1_028290	COG2963	transposase activity
ACGSH8M1_028300	COG2801	Transposase and inactivated derivatives
ACGSH8M1_028460	COG1538	Outer membrane efflux protein
ACGSH8M1_028470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACGSH8M1_028480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACGSH8M1_028490	COG1309	transcriptional regulator
ACGSH8M1_028520	COG1946	Acyl-CoA thioesterase
ACGSH8M1_028540	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ACGSH8M1_028560	COG0009	L-threonylcarbamoyladenylate synthase
ACGSH8M1_028570	COG0613	PHP domain protein
ACGSH8M1_028580	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACGSH8M1_028590	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACGSH8M1_028590	COG0512	Glutamine amidotransferase of anthranilate synthase
ACGSH8M1_028600	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACGSH8M1_028610	COG0134	indole-3-glycerol-phosphate synthase activity
ACGSH8M1_028610	COG0135	phosphoribosylanthranilate isomerase activity
ACGSH8M1_028620	COG0133	tryptophan synthase activity
ACGSH8M1_028630	COG0159	tryptophan synthase activity
ACGSH8M1_028640	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACGSH8M1_028650	COG2963	transposase activity
ACGSH8M1_028660	COG2801	Transposase and inactivated derivatives
ACGSH8M1_028680	COG1396	sequence-specific DNA binding
ACGSH8M1_028690	COG3550	peptidyl-serine autophosphorylation
ACGSH8M1_028700	COG3550	peptidyl-serine autophosphorylation
ACGSH8M1_028740	COG0583	DNA-binding transcription factor activity
ACGSH8M1_028760	COG4521	taurine ABC transporter
ACGSH8M1_028770	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ACGSH8M1_028780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACGSH8M1_028790	COG2175	clavaminate synthase activity
ACGSH8M1_028800	COG5507	3-demethylubiquinone-9 3-methyltransferase
ACGSH8M1_028810	COG2814	Major facilitator Superfamily
ACGSH8M1_028820	COG0109	protoheme IX farnesyltransferase activity
ACGSH8M1_028830	COG0109	protoheme IX farnesyltransferase activity
ACGSH8M1_028840	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ACGSH8M1_028850	COG1845	cytochrome c oxidase, subunit III
ACGSH8M1_028860	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACGSH8M1_028870	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ACGSH8M1_028880	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACGSH8M1_028890	COG0583	DNA-binding transcription factor activity
ACGSH8M1_028930	COG1846	Transcriptional regulator
ACGSH8M1_028960	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
ACGSH8M1_029010	COG0708	Exodeoxyribonuclease III
ACGSH8M1_029030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACGSH8M1_029040	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACGSH8M1_029070	COG0095	Lipoate-protein ligase
ACGSH8M1_029150	COG1285	pathogenesis
ACGSH8M1_029210	COG0484	heat shock protein binding
ACGSH8M1_029220	COG0443	Heat shock 70 kDa protein
ACGSH8M1_029230	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACGSH8M1_029240	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACGSH8M1_029250	COG3706	GGDEF domain
ACGSH8M1_029260	COG0497	DNA recombination
ACGSH8M1_029280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACGSH8M1_029290	COG1136	(ABC) transporter
ACGSH8M1_029290	COG0577	efflux transmembrane transporter activity
ACGSH8M1_029300	COG1538	Outer membrane efflux protein
ACGSH8M1_029310	COG2375	cellular response to nickel ion
ACGSH8M1_029320	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACGSH8M1_029330	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACGSH8M1_029350	COG2916	Histone family protein nucleoid-structuring protein H-NS
ACGSH8M1_029360	COG0583	DNA-binding transcription factor activity
ACGSH8M1_029370	COG3048	D-serine ammonia-lyase activity
ACGSH8M1_029390	COG0538	isocitrate dehydrogenase activity
ACGSH8M1_029460	COG0456	acetyltransferase
ACGSH8M1_029470	COG1187	pseudouridine synthase activity
ACGSH8M1_029490	COG0482	sulfurtransferase activity
ACGSH8M1_029500	COG2915	High frequency lysogenization protein hflD homolog
ACGSH8M1_029510	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ACGSH8M1_029520	COG2850	peptidyl-arginine hydroxylation
ACGSH8M1_029540	COG1196	nuclear chromosome segregation
ACGSH8M1_029540	COG3264	Mechanosensitive ion channel
ACGSH8M1_029600	COG0281	malic enzyme
ACGSH8M1_029610	COG0746	molybdenum cofactor guanylyltransferase activity
ACGSH8M1_029620	COG1763	Mo-molybdopterin cofactor biosynthetic process
ACGSH8M1_029630	COG1289	transmembrane transporter activity
ACGSH8M1_029640	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ACGSH8M1_029700	COG3220	belongs to the UPF0276 family
ACGSH8M1_029720	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACGSH8M1_029750	COG2815	serine threonine protein kinase
ACGSH8M1_029750	COG0515	serine threonine protein kinase
ACGSH8M1_029770	COG4319	ketosteroid isomerase
ACGSH8M1_029780	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACGSH8M1_029790	COG0083	homoserine kinase activity
ACGSH8M1_029810	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
ACGSH8M1_029820	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
ACGSH8M1_029850	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACGSH8M1_029880	COG0745	RESPONSE REGULATOR receiver
ACGSH8M1_029890	COG4988	ABC transporter
ACGSH8M1_029900	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ACGSH8M1_029940	COG1720	tRNA m6t6A37 methyltransferase activity
ACGSH8M1_029970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACGSH8M1_029980	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACGSH8M1_029990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACGSH8M1_030010	COG2190	(PTS) system
ACGSH8M1_030020	COG3038	cytochrome b561
ACGSH8M1_030040	COG0420	3'-5' exonuclease activity
ACGSH8M1_030050	COG1247	-acetyltransferase
ACGSH8M1_030060	COG2974	May be involved in recombination
ACGSH8M1_030080	COG0405	Gamma-glutamyltransferase
ACGSH8M1_030090	COG4651	solute:proton antiporter activity
ACGSH8M1_030090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACGSH8M1_030160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACGSH8M1_030170	COG1917	Cupin 2, conserved barrel domain protein
ACGSH8M1_030170	COG1396	sequence-specific DNA binding
ACGSH8M1_030180	COG1012	belongs to the aldehyde dehydrogenase family
ACGSH8M1_030210	COG0531	amino acid
ACGSH8M1_030230	COG0531	amino acid
ACGSH8M1_030250	COG1283	sodium-dependent phosphate transmembrane transporter activity
ACGSH8M1_030270	COG3384	dioxygenase
ACGSH8M1_030280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACGSH8M1_030280	COG2205	protein histidine kinase activity
ACGSH8M1_030320	COG1388	LysM domain
ACGSH8M1_030320	COG1376	ErfK ybiS ycfS ynhG family protein
ACGSH8M1_030350	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
ACGSH8M1_030360	COG0791	NLP P60 protein
ACGSH8M1_030380	COG3118	belongs to the thioredoxin family
ACGSH8M1_030400	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACGSH8M1_030410	COG0788	formyltetrahydrofolate deformylase activity
ACGSH8M1_030460	COG0741	lytic transglycosylase activity
ACGSH8M1_030460	COG1196	nuclear chromosome segregation
ACGSH8M1_030460	COG0739	heme binding
ACGSH8M1_030470	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ACGSH8M1_030480	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ACGSH8M1_030490	COG0673	inositol 2-dehydrogenase activity
ACGSH8M1_030580	COG3039	Transposase
ACGSH8M1_030590	COG1032	radical SAM domain protein
ACGSH8M1_030600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACGSH8M1_030620	COG3706	GGDEF domain
ACGSH8M1_030630	COG1752	Esterase of the alpha-beta hydrolase superfamily
ACGSH8M1_030640	COG0733	neurotransmitter:sodium symporter activity
ACGSH8M1_030700	COG0281	malic enzyme
ACGSH8M1_030710	COG2207	Transcriptional regulator
ACGSH8M1_030740	COG0745	RESPONSE REGULATOR receiver
ACGSH8M1_030740	COG3706	GGDEF domain
ACGSH8M1_030750	COG2233	PERMEase
ACGSH8M1_030760	COG0095	Lipoate-protein ligase
ACGSH8M1_030770	COG1115	amino acid carrier protein
ACGSH8M1_030780	COG0019	diaminopimelate decarboxylase activity
ACGSH8M1_030800	COG0678	peroxiredoxin activity
ACGSH8M1_030810	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ACGSH8M1_030830	COG1126	abc transporter atp-binding protein
ACGSH8M1_030840	COG0765	amino acid transport
ACGSH8M1_030850	COG4597	amino acid ABC transporter
ACGSH8M1_030860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACGSH8M1_030880	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ACGSH8M1_030890	COG1131	(ABC) transporter
ACGSH8M1_030900	COG0545	Peptidyl-prolyl cis-trans isomerase
ACGSH8M1_030920	COG1940	carbohydrate kinase activity
ACGSH8M1_030940	COG4783	chaperone-mediated protein folding
ACGSH8M1_030960	COG5002	protein histidine kinase activity
ACGSH8M1_030970	COG0745	RESPONSE REGULATOR receiver
ACGSH8M1_030980	COG0346	lactoylglutathione lyase activity
ACGSH8M1_030990	COG3706	GGDEF domain
ACGSH8M1_031000	COG3284	Transcriptional regulator
ACGSH8M1_031010	COG1012	belongs to the aldehyde dehydrogenase family
ACGSH8M1_031030	COG0697	spore germination
ACGSH8M1_031040	COG0667	Aldo Keto reductase
ACGSH8M1_031070	COG3290	protein histidine kinase activity
ACGSH8M1_031090	COG1566	PFAM secretion protein HlyD family protein
ACGSH8M1_031140	COG0602	queuosine metabolic process
ACGSH8M1_031150	COG1328	CTP reductase activity
ACGSH8M1_031170	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ACGSH8M1_031180	COG3115	cell septum assembly
ACGSH8M1_031190	COG1196	nuclear chromosome segregation
ACGSH8M1_031210	COG2860	membrane
ACGSH8M1_031230	COG3108	Peptidase M15
ACGSH8M1_031240	COG2989	Protein conserved in bacteria
ACGSH8M1_031270	COG0463	Glycosyl transferase, family 2
ACGSH8M1_031300	COG0366	Alpha amylase catalytic
ACGSH8M1_031370	COG3706	GGDEF domain
ACGSH8M1_031380	COG0037	tRNA processing
ACGSH8M1_031390	COG3590	peptidase
ACGSH8M1_031410	COG0488	(ABC) transporter
ACGSH8M1_031440	COG0531	amino acid
ACGSH8M1_031450	COG0814	amino acid
ACGSH8M1_031480	COG0825	malonyl-CoA metabolic process
ACGSH8M1_031490	COG0587	DNA-directed DNA polymerase activity
ACGSH8M1_031500	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ACGSH8M1_031510	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACGSH8M1_031520	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACGSH8M1_031530	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ACGSH8M1_031540	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACGSH8M1_031570	COG0750	zinc metalloprotease
ACGSH8M1_031580	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ACGSH8M1_031590	COG0575	Belongs to the CDS family
ACGSH8M1_031610	COG0233	cytoplasmic translational termination
ACGSH8M1_031620	COG0528	UMP kinase activity
ACGSH8M1_031630	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ACGSH8M1_031640	COG0052	Belongs to the universal ribosomal protein uS2 family
ACGSH8M1_031650	COG0024	Methionine aminopeptidase
ACGSH8M1_031660	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ACGSH8M1_031670	COG2171	N-acyltransferase activity
ACGSH8M1_031690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACGSH8M1_031690	COG1263	PTS System
ACGSH8M1_031710	COG4580	involved in the transport of maltose and maltodextrins
ACGSH8M1_031740	COG0564	pseudouridine synthase activity
ACGSH8M1_031750	COG3098	single-species biofilm formation
ACGSH8M1_031800	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
ACGSH8M1_031820	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ACGSH8M1_031820	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ACGSH8M1_031840	COG3706	GGDEF domain
ACGSH8M1_031850	COG1611	Belongs to the LOG family
ACGSH8M1_031860	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACGSH8M1_031870	COG0473	3-isopropylmalate dehydrogenase activity
ACGSH8M1_031890	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
ACGSH8M1_031920	COG0583	DNA-binding transcription factor activity
ACGSH8M1_031930	COG0840	transmembrane signaling receptor activity
ACGSH8M1_031940	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACGSH8M1_031970	COG1477	protein flavinylation
ACGSH8M1_031980	COG2871	sodium ion transport
ACGSH8M1_031990	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ACGSH8M1_032000	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ACGSH8M1_032010	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ACGSH8M1_032020	COG1805	sodium ion transport
ACGSH8M1_032030	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ACGSH8M1_032050	COG0271	Belongs to the BolA IbaG family
ACGSH8M1_032060	COG2813	Specifically methylates the guanine in position
ACGSH8M1_032080	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACGSH8M1_032100	COG2211	Major facilitator Superfamily
ACGSH8M1_032110	COG3248	Nucleoside-binding outer membrane protein
ACGSH8M1_032120	COG1666	GTP binding
ACGSH8M1_032130	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ACGSH8M1_032150	COG0659	secondary active sulfate transmembrane transporter activity
ACGSH8M1_032160	COG5000	phosphorelay sensor kinase activity
ACGSH8M1_032160	COG5002	protein histidine kinase activity
ACGSH8M1_032180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACGSH8M1_032190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACGSH8M1_032310	COG0582	viral genome integration into host DNA
ACGSH8M1_032330	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACGSH8M1_032350	COG1151	hydroxylamine reductase activity
ACGSH8M1_032360	COG0783	Belongs to the Dps family
ACGSH8M1_032410	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACGSH8M1_032440	COG0300	oxidoreductase activity
ACGSH8M1_032460	COG0415	Belongs to the DNA photolyase family
ACGSH8M1_032470	COG0789	Transcriptional regulator
ACGSH8M1_032480	COG3272	Protein of unknown function (DUF1722)
ACGSH8M1_032530	COG0077	Prephenate dehydratase
ACGSH8M1_032530	COG1605	Chorismate mutase
ACGSH8M1_032580	COG2133	pyrroloquinoline quinone binding
ACGSH8M1_032600	COG1349	DNA-binding transcription factor activity
ACGSH8M1_032610	COG2084	Dehydrogenase
ACGSH8M1_032630	COG0235	Class ii aldolase
ACGSH8M1_032640	COG3622	Belongs to the hyi family
ACGSH8M1_032650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACGSH8M1_032660	COG2610	gluconate transmembrane transporter activity
ACGSH8M1_032700	COG3385	transposase activity
ACGSH8M1_032710	COG0300	oxidoreductase activity
ACGSH8M1_032760	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ACGSH8M1_032800	COG3813	Protein conserved in bacteria
ACGSH8M1_032820	COG0826	peptidase U32
ACGSH8M1_032830	COG1280	lysine exporter protein (LysE YggA)
ACGSH8M1_032890	COG3275	phosphorelay sensor kinase activity
ACGSH8M1_032900	COG3279	Response regulator of the LytR AlgR family
ACGSH8M1_032910	COG1966	Carbon starvation protein
ACGSH8M1_032930	COG0114	fumarate hydratase activity
ACGSH8M1_032950	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ACGSH8M1_032950	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ACGSH8M1_032950	COG0506	proline dehydrogenase activity
ACGSH8M1_032960	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ACGSH8M1_032970	COG0305	Participates in initiation and elongation during chromosome replication
ACGSH8M1_033000	COG0737	Belongs to the 5'-nucleotidase family
ACGSH8M1_033040	COG2204	response regulator
ACGSH8M1_033050	COG0545	Peptidyl-prolyl cis-trans isomerase
ACGSH8M1_033070	COG2900	Belongs to the SlyX family
ACGSH8M1_033080	COG1047	Peptidyl-prolyl cis-trans
ACGSH8M1_033090	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ACGSH8M1_033110	COG0784	Response regulator, receiver
ACGSH8M1_033110	COG0835	chemotaxis
ACGSH8M1_033120	COG0429	hydrolase of the alpha beta-hydrolase fold
ACGSH8M1_033130	COG4251	negative regulation of phosphorylation
ACGSH8M1_033130	COG5001	Diguanylate cyclase
ACGSH8M1_033130	COG2203	Gaf domain
ACGSH8M1_033130	COG3706	GGDEF domain
ACGSH8M1_033140	COG3089	Belongs to the UPF0270 family
ACGSH8M1_033150	COG3954	Phosphoribulokinase
ACGSH8M1_033180	COG1765	OsmC-like protein
ACGSH8M1_033190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACGSH8M1_033200	COG2226	methyltransferase
ACGSH8M1_033220	COG2205	protein histidine kinase activity
ACGSH8M1_033220	COG2202	Pas domain
ACGSH8M1_033230	COG2814	Major facilitator Superfamily
ACGSH8M1_033280	COG0748	coenzyme F420 binding
ACGSH8M1_033290	COG3721	Heme iron utilization protein
ACGSH8M1_033310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACGSH8M1_033360	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ACGSH8M1_033380	COG0463	Glycosyl transferase, family 2
ACGSH8M1_033390	COG0739	heme binding
ACGSH8M1_033390	COG1196	nuclear chromosome segregation
ACGSH8M1_033390	COG0741	lytic transglycosylase activity
ACGSH8M1_033400	COG0488	(ABC) transporter
ACGSH8M1_033420	COG2252	PERMEase
ACGSH8M1_033430	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ACGSH8M1_033440	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ACGSH8M1_033450	COG3178	'Phosphotransferase
ACGSH8M1_033460	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ACGSH8M1_033480	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ACGSH8M1_033490	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACGSH8M1_033510	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ACGSH8M1_033530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACGSH8M1_033540	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ACGSH8M1_033550	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ACGSH8M1_033570	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACGSH8M1_033580	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ACGSH8M1_033590	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ACGSH8M1_033600	COG0142	geranyltranstransferase activity
ACGSH8M1_033610	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ACGSH8M1_033620	COG0330	HflC and HflK could
ACGSH8M1_033630	COG0330	HflC and HflK could
ACGSH8M1_033640	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACGSH8M1_033650	COG1923	regulation of RNA biosynthetic process
ACGSH8M1_033660	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ACGSH8M1_033670	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ACGSH8M1_033690	COG0802	atpase or kinase
ACGSH8M1_033700	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACGSH8M1_033700	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ACGSH8M1_033740	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACGSH8M1_033750	COG2011	ABC-type metal ion transport system permease component
ACGSH8M1_033760	COG1464	Belongs to the NlpA lipoprotein family
ACGSH8M1_033800	COG0784	Response regulator, receiver
ACGSH8M1_033800	COG2205	protein histidine kinase activity
ACGSH8M1_033830	COG0784	Response regulator, receiver
ACGSH8M1_033830	COG5002	protein histidine kinase activity
ACGSH8M1_033830	COG2198	Histidine kinase
ACGSH8M1_033870	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
ACGSH8M1_033900	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ACGSH8M1_033910	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ACGSH8M1_033920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACGSH8M1_033930	COG2716	regulation of RNA biosynthetic process
ACGSH8M1_033940	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACGSH8M1_033950	COG3013	Belongs to the UPF0304 family
ACGSH8M1_033970	COG3092	negative regulation of chromosome organization
ACGSH8M1_033980	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ACGSH8M1_033990	COG0857	belongs to the CobB CobQ family
ACGSH8M1_033990	COG0280	phosphate acetyltransferase
ACGSH8M1_034000	COG0440	acetolactate synthase activity
ACGSH8M1_034010	COG0028	Belongs to the TPP enzyme family
ACGSH8M1_034040	COG0671	phosphoesterase, PA-phosphatase related
ACGSH8M1_034060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACGSH8M1_034070	COG0473	3-isopropylmalate dehydrogenase activity
ACGSH8M1_034080	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ACGSH8M1_034090	COG0066	3-isopropylmalate dehydratase activity
ACGSH8M1_034120	COG4143	(ABC) transporter
ACGSH8M1_034130	COG1178	ABC-type Fe3 transport system permease component
ACGSH8M1_034140	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
ACGSH8M1_034160	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ACGSH8M1_034180	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACGSH8M1_034200	COG0316	Belongs to the HesB IscA family
ACGSH8M1_034220	COG0038	chloride channel
ACGSH8M1_034230	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ACGSH8M1_034260	COG0671	phosphoesterase, PA-phosphatase related
ACGSH8M1_034280	COG0583	DNA-binding transcription factor activity
ACGSH8M1_034290	COG2076	Multidrug Resistance protein
ACGSH8M1_034310	COG0346	lactoylglutathione lyase activity
ACGSH8M1_034320	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACGSH8M1_034330	COG1643	Atp-dependent helicase
ACGSH8M1_034350	COG1489	DNA binding
ACGSH8M1_034360	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ACGSH8M1_034370	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACGSH8M1_034390	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACGSH8M1_034400	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ACGSH8M1_034410	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ACGSH8M1_034430	COG0842	Transport permease protein
ACGSH8M1_034440	COG1131	(ABC) transporter
ACGSH8M1_034470	COG0163	prenyltransferase activity
ACGSH8M1_034480	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACGSH8M1_034490	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ACGSH8M1_034520	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ACGSH8M1_034550	COG1136	(ABC) transporter
ACGSH8M1_034640	COG2801	Transposase and inactivated derivatives
ACGSH8M1_034650	COG0529	Catalyzes the synthesis of activated sulfate
ACGSH8M1_034660	COG0471	metal ion transport
ACGSH8M1_034660	COG3273	potassium ion transport
ACGSH8M1_034670	COG2895	sulfate adenylyltransferase (ATP) activity
ACGSH8M1_034680	COG0175	sulfate reduction
ACGSH8M1_034690	COG1648	precorrin-2 dehydrogenase activity
ACGSH8M1_034690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACGSH8M1_034700	COG0330	HflC and HflK could
ACGSH8M1_034710	COG1585	Membrane protein implicated in regulation of membrane protease activity
ACGSH8M1_034730	COG0673	inositol 2-dehydrogenase activity
ACGSH8M1_034750	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ACGSH8M1_034760	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACGSH8M1_034770	COG3036	rescue of stalled ribosome
ACGSH8M1_034800	COG0138	bifunctional purine biosynthesis protein purh
ACGSH8M1_034810	COG0151	Belongs to the GarS family
ACGSH8M1_034860	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACGSH8M1_034870	COG0358	DNA primase activity
ACGSH8M1_034880	COG1610	YqeY-like protein
ACGSH8M1_034890	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ACGSH8M1_034900	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ACGSH8M1_034910	COG3385	transposase activity
ACGSH8M1_034930	COG1388	LysM domain
ACGSH8M1_034930	COG4942	peptidase
ACGSH8M1_034940	COG1238	metal cluster binding
ACGSH8M1_034950	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ACGSH8M1_034960	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ACGSH8M1_034970	COG0585	pseudouridine synthase activity
ACGSH8M1_034990	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ACGSH8M1_035000	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ACGSH8M1_035010	COG0148	phosphopyruvate hydratase activity
ACGSH8M1_035020	COG0504	CTP synthase activity
ACGSH8M1_035030	COG3956	TIGRFAM MazG family protein
ACGSH8M1_035040	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACGSH8M1_035050	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACGSH8M1_035070	COG4807	Protein conserved in bacteria
ACGSH8M1_035080	COG3023	N-Acetylmuramoyl-L-alanine amidase
ACGSH8M1_035090	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ACGSH8M1_035100	COG1381	Involved in DNA repair and RecF pathway recombination
ACGSH8M1_035120	COG0571	ribonuclease III activity
ACGSH8M1_035130	COG0681	Belongs to the peptidase S26 family
ACGSH8M1_035140	COG0481	GTPase activity
ACGSH8M1_035170	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
ACGSH8M1_035180	COG1595	DNA-templated transcription, initiation
ACGSH8M1_035190	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ACGSH8M1_035210	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ACGSH8M1_035230	COG0583	DNA-binding transcription factor activity
ACGSH8M1_035290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACGSH8M1_035310	COG0126	phosphoglycerate kinase activity
ACGSH8M1_035320	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ACGSH8M1_035330	COG1940	carbohydrate kinase activity
ACGSH8M1_035340	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ACGSH8M1_035360	COG4991	sh3 domain protein
ACGSH8M1_035370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACGSH8M1_035400	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ACGSH8M1_035410	COG1028	Short-chain dehydrogenase reductase Sdr
ACGSH8M1_035430	COG1505	serine-type exopeptidase activity
ACGSH8M1_035440	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACGSH8M1_035450	COG0765	amino acid transport
ACGSH8M1_035470	COG0765	amino acid transport
ACGSH8M1_035480	COG1126	abc transporter atp-binding protein
ACGSH8M1_035490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACGSH8M1_035510	COG3174	membrane
ACGSH8M1_035520	COG0110	maltose O-acetyltransferase activity
ACGSH8M1_035580	COG1942	4-Oxalocrotonate Tautomerase
ACGSH8M1_035600	COG0583	DNA-binding transcription factor activity
ACGSH8M1_035610	COG0165	Argininosuccinate lyase
ACGSH8M1_035620	COG0137	argininosuccinate synthase activity
ACGSH8M1_035640	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ACGSH8M1_035650	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ACGSH8M1_035670	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ACGSH8M1_035680	COG3447	MASE1 domain protein
ACGSH8M1_035680	COG5002	protein histidine kinase activity
ACGSH8M1_035680	COG5001	Diguanylate cyclase
ACGSH8M1_035690	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ACGSH8M1_035760	COG0583	DNA-binding transcription factor activity
ACGSH8M1_035770	COG1380	Effector of murein hydrolase LrgA
ACGSH8M1_035780	COG1346	cytolysis
ACGSH8M1_035790	COG0460	homoserine dehydrogenase
ACGSH8M1_035790	COG0527	aspartate kinase activity
ACGSH8M1_035800	COG0626	cystathionine gamma-synthase activity
ACGSH8M1_035830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACGSH8M1_035840	COG0814	amino acid
ACGSH8M1_035850	COG1218	3'(2'),5'-bisphosphate nucleotidase
ACGSH8M1_035860	COG0494	nUDIX hydrolase
ACGSH8M1_035870	COG1011	Hydrolase
ACGSH8M1_035880	COG1902	pentaerythritol trinitrate reductase activity
ACGSH8M1_035900	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ACGSH8M1_035930	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ACGSH8M1_035950	COG3156	type II secretion system protein K
ACGSH8M1_035960	COG4795	General secretion pathway protein
ACGSH8M1_035970	COG2165	general secretion pathway protein
ACGSH8M1_035990	COG2165	general secretion pathway protein
ACGSH8M1_036000	COG1459	type II secretion system
ACGSH8M1_036010	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACGSH8M1_036030	COG3031	protein transport across the cell outer membrane
ACGSH8M1_036050	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ACGSH8M1_036060	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ACGSH8M1_036100	COG3133	Outer membrane lipoprotein
ACGSH8M1_036110	COG3025	triphosphatase activity
ACGSH8M1_036120	COG1392	Phosphate transport regulator
ACGSH8M1_036130	COG0306	phosphate transporter
ACGSH8M1_036140	COG0617	tRNA 3'-terminal CCA addition
ACGSH8M1_036150	COG3267	Type II secretory pathway component ExeA
ACGSH8M1_036150	COG3409	Peptidoglycan-binding domain 1 protein
ACGSH8M1_036170	COG1194	a g-specific adenine glycosylase
ACGSH8M1_036180	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ACGSH8M1_036210	COG3240	lipase activity
ACGSH8M1_036230	COG3009	Protein conserved in bacteria
ACGSH8M1_036240	COG3008	intermembrane lipid transfer
ACGSH8M1_036240	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ACGSH8M1_036250	COG2995	paraquat-inducible protein a
ACGSH8M1_036270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACGSH8M1_036280	COG5001	Diguanylate cyclase
ACGSH8M1_036280	COG4251	negative regulation of phosphorylation
ACGSH8M1_036280	COG3706	GGDEF domain
ACGSH8M1_036280	COG2203	Gaf domain
ACGSH8M1_036290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACGSH8M1_036300	COG2813	Specifically methylates the guanine in position
ACGSH8M1_036310	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ACGSH8M1_036320	COG0297	glycogen (starch) synthase activity
ACGSH8M1_036350	COG1757	Na H antiporter
ACGSH8M1_036360	COG0583	DNA-binding transcription factor activity
ACGSH8M1_036370	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ACGSH8M1_036380	COG3842	ATPase activity
ACGSH8M1_036390	COG1176	ABC-type spermidine putrescine transport system, permease component I
ACGSH8M1_036400	COG1177	transmembrane transport
ACGSH8M1_036410	COG1012	belongs to the aldehyde dehydrogenase family
ACGSH8M1_036420	COG0109	protoheme IX farnesyltransferase activity
ACGSH8M1_036480	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ACGSH8M1_036500	COG1565	acr, cog1565
ACGSH8M1_036500	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ACGSH8M1_036510	COG1444	tRNA N-acetyltransferase activity
ACGSH8M1_036550	COG1803	Methylglyoxal synthase
ACGSH8M1_036580	COG0252	asparaginase activity
ACGSH8M1_036620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACGSH8M1_036620	COG1263	PTS System
ACGSH8M1_036630	COG0366	Alpha amylase catalytic
ACGSH8M1_036640	COG0110	maltose O-acetyltransferase activity
ACGSH8M1_036650	COG1522	sequence-specific DNA binding
ACGSH8M1_036710	COG3068	Protein conserved in bacteria
ACGSH8M1_036730	COG0739	heme binding
ACGSH8M1_036770	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ACGSH8M1_036780	COG1121	(ABC) transporter
ACGSH8M1_036790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACGSH8M1_036800	COG0583	DNA-binding transcription factor activity
ACGSH8M1_036820	COG1573	uracil-dna glycosylase
ACGSH8M1_036830	COG2962	Rard protein
ACGSH8M1_036840	COG2827	Endonuclease containing a URI domain
ACGSH8M1_036870	COG1842	Phage shock protein A
ACGSH8M1_036880	COG0204	Acyl-transferase
ACGSH8M1_036920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACGSH8M1_036940	COG0484	heat shock protein binding
ACGSH8M1_037050	COG0187	DNA topoisomerase II activity
ACGSH8M1_037060	COG1289	transmembrane transporter activity
ACGSH8M1_037070	COG1566	PFAM secretion protein HlyD family protein
ACGSH8M1_037100	COG1051	belongs to the nudix hydrolase family
ACGSH8M1_037110	COG3150	esterase
ACGSH8M1_037130	COG3151	Protein conserved in bacteria
ACGSH8M1_037140	COG0494	nUDIX hydrolase
ACGSH8M1_037150	COG1538	Outer membrane efflux protein
ACGSH8M1_037170	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ACGSH8M1_037170	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ACGSH8M1_037180	COG1560	Kdo2-lipid A biosynthetic process
ACGSH8M1_037210	COG2771	luxR family
ACGSH8M1_037220	COG3916	Acyl-homoserine-lactone synthase
ACGSH8M1_037240	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
ACGSH8M1_037250	COG2213	PTS system mannitol-specific
ACGSH8M1_037250	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACGSH8M1_037260	COG0246	Mannitol dehydrogenase
ACGSH8M1_037270	COG3722	fumarate hydratase activity
ACGSH8M1_037280	COG3263	regulation of cellular component size
ACGSH8M1_037320	COG1671	Belongs to the UPF0178 family
ACGSH8M1_037360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ACGSH8M1_037370	COG0513	Belongs to the DEAD box helicase family
ACGSH8M1_037410	COG3385	transposase activity
ACGSH8M1_037420	COG1575	Belongs to the MenA family. Type 1 subfamily
ACGSH8M1_037430	COG1169	isochorismate synthase
ACGSH8M1_037440	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ACGSH8M1_037450	COG0596	Alpha beta hydrolase
ACGSH8M1_037460	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ACGSH8M1_037480	COG0318	PFAM AMP-dependent synthetase and ligase
ACGSH8M1_037490	COG3291	Pkd domain containing protein
ACGSH8M1_037500	COG2949	membrane
ACGSH8M1_037530	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ACGSH8M1_037590	COG2873	o-acetylhomoserine
ACGSH8M1_037610	COG1979	alcohol dehydrogenase
ACGSH8M1_037640	COG4221	oxidoreductase activity
ACGSH8M1_037680	COG1285	pathogenesis
ACGSH8M1_037710	COG1368	sulfuric ester hydrolase activity
ACGSH8M1_037720	COG1522	sequence-specific DNA binding
ACGSH8M1_037740	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ACGSH8M1_037760	COG1546	Belongs to the CinA family
ACGSH8M1_037760	COG1058	Belongs to the CinA family
ACGSH8M1_037770	COG1988	membrane-bound metal-dependent
ACGSH8M1_037800	COG0561	phosphatase activity
ACGSH8M1_037810	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ACGSH8M1_037830	COG1011	Hydrolase
ACGSH8M1_037860	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ACGSH8M1_037870	COG0019	diaminopimelate decarboxylase activity
ACGSH8M1_037880	COG1965	Belongs to the frataxin family
ACGSH8M1_037890	COG0400	carboxylic ester hydrolase activity
ACGSH8M1_037900	COG3072	Adenylate cyclase
ACGSH8M1_037910	COG0181	hydroxymethylbilane synthase activity
ACGSH8M1_037930	COG2959	enzyme of heme biosynthesis
ACGSH8M1_037940	COG3071	HemY protein
ACGSH8M1_037960	COG0312	modulator of DNA gyrase
ACGSH8M1_037970	COG3028	Belongs to the UPF0307 family
ACGSH8M1_037990	COG2926	Belongs to the UPF0265 family
ACGSH8M1_038020	COG1396	sequence-specific DNA binding
ACGSH8M1_038030	COG3135	benzoate transporter
ACGSH8M1_038090	COG3047	cAMP biosynthetic process
ACGSH8M1_038100	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACGSH8M1_038110	COG2197	response regulator
ACGSH8M1_038210	COG5433	transposase activity
ACGSH8M1_038230	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ACGSH8M1_038320	COG0457	Tetratricopeptide repeat
ACGSH8M1_038330	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ACGSH8M1_038340	COG1215	transferase activity, transferring glycosyl groups
ACGSH8M1_038400	COG5499	transcription regulator containing HTH domain
ACGSH8M1_038410	COG2916	Histone family protein nucleoid-structuring protein H-NS
ACGSH8M1_038430	COG3039	Transposase
ACGSH8M1_038510	COG1278	Cold shock
ACGSH8M1_038520	COG2205	protein histidine kinase activity
ACGSH8M1_038530	COG0745	RESPONSE REGULATOR receiver
ACGSH8M1_038570	COG3706	GGDEF domain
ACGSH8M1_038580	COG0347	Belongs to the P(II) protein family
ACGSH8M1_038590	COG0004	ammonium transporteR
ACGSH8M1_038610	COG0346	lactoylglutathione lyase activity
ACGSH8M1_038630	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ACGSH8M1_038640	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACGSH8M1_038650	COG1074	ATP-dependent DNA helicase activity
ACGSH8M1_038660	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ACGSH8M1_038670	COG2259	Doxx family
ACGSH8M1_038680	COG1741	Belongs to the pirin family
ACGSH8M1_038700	COG0583	DNA-binding transcription factor activity
ACGSH8M1_038750	COG1175	transmembrane transport
ACGSH8M1_038770	COG3842	ATPase activity
ACGSH8M1_038790	COG0745	RESPONSE REGULATOR receiver
ACGSH8M1_038790	COG3706	GGDEF domain
ACGSH8M1_038830	COG0456	acetyltransferase
ACGSH8M1_038840	COG0753	catalase activity
ACGSH8M1_038880	COG0494	nUDIX hydrolase
ACGSH8M1_038890	COG0628	permease
ACGSH8M1_038910	COG2957	Belongs to the agmatine deiminase family
ACGSH8M1_038940	COG2957	Belongs to the agmatine deiminase family
ACGSH8M1_038950	COG0583	DNA-binding transcription factor activity
ACGSH8M1_038980	COG1461	Dihydroxyacetone kinase
ACGSH8M1_038990	COG2376	Dihydroxyacetone kinase
ACGSH8M1_039000	COG2252	PERMEase
ACGSH8M1_039010	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ACGSH8M1_039020	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ACGSH8M1_039030	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ACGSH8M1_039040	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ACGSH8M1_039050	COG0049	tRNA binding
ACGSH8M1_039060	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ACGSH8M1_039070	COG2168	tRNA wobble position uridine thiolation
ACGSH8M1_039090	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ACGSH8M1_039100	COG0251	oxidation-reduction process
ACGSH8M1_039110	COG2964	Protein conserved in bacteria
ACGSH8M1_039120	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ACGSH8M1_039130	COG0085	RNA polymerase activity
ACGSH8M1_039140	COG0222	ribosome binding
ACGSH8M1_039150	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ACGSH8M1_039160	COG0081	regulation of translation
ACGSH8M1_039170	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ACGSH8M1_039180	COG0250	Participates in transcription elongation, termination and antitermination
ACGSH8M1_039190	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ACGSH8M1_039200	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ACGSH8M1_039230	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ACGSH8M1_039240	COG0569	domain protein
ACGSH8M1_039250	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ACGSH8M1_039260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACGSH8M1_039270	COG3005	denitrification pathway
ACGSH8M1_039280	COG0243	molybdopterin cofactor binding
ACGSH8M1_039300	COG2205	protein histidine kinase activity
ACGSH8M1_039310	COG0745	RESPONSE REGULATOR receiver
ACGSH8M1_039350	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ACGSH8M1_039380	COG2204	response regulator
ACGSH8M1_039400	COG2205	protein histidine kinase activity
ACGSH8M1_039440	COG0517	IMP dehydrogenase activity
ACGSH8M1_039440	COG0516	GMP reductase activity
ACGSH8M1_039460	COG1522	sequence-specific DNA binding
ACGSH8M1_039470	COG2502	aspartate--ammonia ligase
ACGSH8M1_039500	COG0583	DNA-binding transcription factor activity
ACGSH8M1_039510	COG0542	response to heat
ACGSH8M1_039530	COG0564	pseudouridine synthase activity
ACGSH8M1_039540	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACGSH8M1_039550	COG3681	Belongs to the UPF0597 family
ACGSH8M1_039560	COG2964	Protein conserved in bacteria
ACGSH8M1_039570	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ACGSH8M1_039580	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ACGSH8M1_039590	COG1979	alcohol dehydrogenase
ACGSH8M1_039600	COG2207	Transcriptional regulator
ACGSH8M1_039610	COG3040	lipid binding
ACGSH8M1_039650	COG0583	DNA-binding transcription factor activity
ACGSH8M1_039680	COG0540	Belongs to the ATCase OTCase family
ACGSH8M1_039690	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
ACGSH8M1_039700	COG1438	arginine binding
ACGSH8M1_039710	COG1288	antiporter activity
ACGSH8M1_039720	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ACGSH8M1_039800	COG3250	beta-galactosidase activity
ACGSH8M1_039830	COG1609	Transcriptional regulator
ACGSH8M1_039840	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACGSH8M1_039860	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ACGSH8M1_039870	COG2017	converts alpha-aldose to the beta-anomer
ACGSH8M1_039880	COG0667	Aldo Keto reductase
ACGSH8M1_039890	COG1968	undecaprenyl-diphosphatase activity
ACGSH8M1_039900	COG3806	Anti-sigma factor
ACGSH8M1_039910	COG1595	DNA-templated transcription, initiation
ACGSH8M1_039950	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ACGSH8M1_039960	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ACGSH8M1_039970	COG0477	Major facilitator Superfamily
ACGSH8M1_040000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACGSH8M1_040010	COG1131	(ABC) transporter
ACGSH8M1_040020	COG0842	Transport permease protein
ACGSH8M1_040030	COG0842	Transport permease protein
ACGSH8M1_040040	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACGSH8M1_040060	COG2146	nitrite reductase [NAD(P)H] activity
ACGSH8M1_040070	COG2116	formate transmembrane transporter activity
ACGSH8M1_040080	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACGSH8M1_040080	COG1648	precorrin-2 dehydrogenase activity
ACGSH8M1_040090	COG2239	Acts as a magnesium transporter
ACGSH8M1_040100	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACGSH8M1_040110	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ACGSH8M1_040130	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ACGSH8M1_040150	COG0514	ATP-dependent DNA helicase (RecQ)
ACGSH8M1_040160	COG2050	protein possibly involved in aromatic compounds catabolism
ACGSH8M1_040180	COG2258	MOSC domain
ACGSH8M1_040190	COG1177	transmembrane transport
ACGSH8M1_040200	COG1176	ABC-type spermidine putrescine transport system, permease component I
ACGSH8M1_040210	COG3842	ATPase activity
ACGSH8M1_040250	COG0174	glutamine synthetase
ACGSH8M1_040260	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ACGSH8M1_040290	COG3045	CreA protein
ACGSH8M1_040300	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACGSH8M1_040310	COG0443	Heat shock 70 kDa protein
ACGSH8M1_040340	COG0366	Alpha amylase catalytic
ACGSH8M1_040370	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACGSH8M1_040380	COG0745	RESPONSE REGULATOR receiver
ACGSH8M1_040390	COG2205	protein histidine kinase activity
ACGSH8M1_040410	COG0281	malic enzyme
ACGSH8M1_040420	COG0702	epimerase
ACGSH8M1_040440	COG0254	rRNA binding
ACGSH8M1_040450	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACGSH8M1_040490	COG0129	dihydroxy-acid dehydratase activity
ACGSH8M1_040500	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACGSH8M1_040510	COG3978	acetolactate synthase activity
ACGSH8M1_040540	COG0606	chelatase, subunit chli
ACGSH8M1_040550	COG0204	Acyl-transferase
ACGSH8M1_040560	COG0204	Acyl-transferase
ACGSH8M1_040570	COG1683	Conserved Protein
ACGSH8M1_040590	COG1335	isochorismatase
ACGSH8M1_040610	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACGSH8M1_040620	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ACGSH8M1_040640	COG3084	Protein conserved in bacteria
ACGSH8M1_040650	COG2203	Gaf domain
ACGSH8M1_040650	COG5001	Diguanylate cyclase
ACGSH8M1_040650	COG3706	GGDEF domain
ACGSH8M1_040650	COG4251	negative regulation of phosphorylation
ACGSH8M1_040680	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ACGSH8M1_040690	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ACGSH8M1_040700	COG1561	YicC-like family, N-terminal region
ACGSH8M1_040720	COG1519	Transferase
ACGSH8M1_040730	COG0859	PFAM glycosyl transferase family 9
ACGSH8M1_040740	COG0463	Glycosyl transferase, family 2
ACGSH8M1_040750	COG0859	PFAM glycosyl transferase family 9
ACGSH8M1_040760	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ACGSH8M1_040770	COG2990	Protein conserved in bacteria
ACGSH8M1_040780	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ACGSH8M1_040800	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ACGSH8M1_040810	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ACGSH8M1_040820	COG2003	Belongs to the UPF0758 family
ACGSH8M1_040830	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACGSH8M1_040840	COG0756	dUTP diphosphatase activity
ACGSH8M1_040850	COG1309	transcriptional regulator
ACGSH8M1_040860	COG0668	transmembrane transport
ACGSH8M1_040880	COG0166	Belongs to the GPI family
ACGSH8M1_040890	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ACGSH8M1_040900	COG0583	DNA-binding transcription factor activity
ACGSH8M1_040920	COG0045	succinate-CoA ligase (ADP-forming) activity
ACGSH8M1_040920	COG1042	CoA-binding domain protein
ACGSH8M1_040920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACGSH8M1_040940	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ACGSH8M1_040950	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ACGSH8M1_040960	COG1739	Uncharacterized protein family UPF0029
ACGSH8M1_040970	COG0006	proline dipeptidase activity
ACGSH8M1_040980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACGSH8M1_040990	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACGSH8M1_040990	COG1024	Enoyl-CoA hydratase
ACGSH8M1_041000	COG0183	Belongs to the thiolase family
ACGSH8M1_041020	COG0745	RESPONSE REGULATOR receiver
ACGSH8M1_041030	COG2205	protein histidine kinase activity
ACGSH8M1_041060	COG0425	Belongs to the sulfur carrier protein TusA family
ACGSH8M1_041070	COG0425	Belongs to the sulfur carrier protein TusA family
ACGSH8M1_041080	COG0251	oxidation-reduction process
ACGSH8M1_041090	COG2885	chlorophyll binding
ACGSH8M1_041110	COG1335	isochorismatase
ACGSH8M1_041120	COG2818	Glycosylase
ACGSH8M1_041130	COG0752	glycyl-tRNA synthetase alpha subunit
ACGSH8M1_041140	COG0751	glycine-tRNA ligase activity
ACGSH8M1_041170	COG4251	negative regulation of phosphorylation
ACGSH8M1_041170	COG2203	Gaf domain
ACGSH8M1_041170	COG3706	GGDEF domain
ACGSH8M1_041170	COG5001	Diguanylate cyclase
ACGSH8M1_041210	COG0814	amino acid
ACGSH8M1_041220	COG0814	amino acid
ACGSH8M1_041250	COG0348	domain, Protein
ACGSH8M1_041270	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACGSH8M1_041280	COG0426	domain, Protein
ACGSH8M1_041280	COG1773	rubredoxin
ACGSH8M1_041290	COG3604	Transcriptional regulator
ACGSH8M1_041300	COG1609	Transcriptional regulator
ACGSH8M1_041320	COG0559	Belongs to the binding-protein-dependent transport system permease family
ACGSH8M1_041380	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACGSH8M1_041410	COG2960	long-chain fatty acid transporting porin activity
ACGSH8M1_041430	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ACGSH8M1_041450	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ACGSH8M1_041460	COG3118	belongs to the thioredoxin family
ACGSH8M1_041470	COG0513	Belongs to the DEAD box helicase family
ACGSH8M1_041480	COG0248	Ppx GppA phosphatase
ACGSH8M1_041500	COG0742	ribosomal rna small subunit methyltransferase
ACGSH8M1_041540	COG0084	hydrolase, TatD family'
ACGSH8M1_041550	COG0805	protein transport
ACGSH8M1_041560	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACGSH8M1_041570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACGSH8M1_041580	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACGSH8M1_041590	COG3165	ubiquinone biosynthetic process from chorismate
ACGSH8M1_041610	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ACGSH8M1_041620	COG0402	S-adenosylhomocysteine deaminase activity
ACGSH8M1_041640	COG3335	DDE superfamily endonuclease
ACGSH8M1_041670	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ACGSH8M1_041680	COG0848	biopolymer transport protein
ACGSH8M1_041690	COG0811	peptide transport
ACGSH8M1_041700	COG0811	peptide transport
ACGSH8M1_041720	COG2771	luxR family
ACGSH8M1_041730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACGSH8M1_041740	COG1349	DNA-binding transcription factor activity
ACGSH8M1_041750	COG0745	RESPONSE REGULATOR receiver
ACGSH8M1_041760	COG2205	protein histidine kinase activity
ACGSH8M1_041780	COG4452	Inner membrane protein CreD
ACGSH8M1_041790	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ACGSH8M1_041800	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ACGSH8M1_041810	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ACGSH8M1_041820	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ACGSH8M1_041830	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ACGSH8M1_041840	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACGSH8M1_041850	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ACGSH8M1_041870	COG0356	it plays a direct role in the translocation of protons across the membrane
ACGSH8M1_041890	COG1475	DNA binding
ACGSH8M1_041900	COG1192	Involved in chromosome partitioning
ACGSH8M1_041910	COG0357	Ribosomal RNA small subunit methyltransferase G
ACGSH8M1_041920	COG0445	tRNA wobble uridine modification
ACGSH8M1_041930	COG0716	FMN binding
ACGSH8M1_041940	COG4774	siderophore transport
ACGSH8M1_041950	COG4615	Cyclic peptide transporter
ACGSH8M1_041960	COG1120	ATPase activity
ACGSH8M1_041970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ACGSH8M1_041990	COG3550	peptidyl-serine autophosphorylation
ACGSH8M1_042030	COG2801	Transposase and inactivated derivatives
ACGSH8M1_042050	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ACGSH8M1_042060	COG0706	membrane insertase activity
ACGSH8M1_042070	COG0594	ribonuclease P activity
ACGSH8M1_042080	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ACGSH8M1_p10090	COG2974	May be involved in recombination
ACGSH8M1_p10180	COG1525	nuclease
ACGSH8M1_p10190	COG0776	regulation of translation
ACGSH8M1_p10240	COG1192	Involved in chromosome partitioning
ACGSH8M1_p10340	COG3385	transposase activity
ACGSH8M1_p10400	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACGSH8M1_p10420	COG0583	DNA-binding transcription factor activity
ACGSH8M1_p10440	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACGSH8M1_p10450	COG0625	glutathione transferase activity
ACGSH8M1_p10490	COG0519	Catalyzes the synthesis of GMP from XMP
ACGSH8M1_p10490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACGSH8M1_p10510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACGSH8M1_p10550	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACGSH8M1_p10570	COG0604	alcohol dehydrogenase
ACGSH8M1_p10580	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ACGSH8M1_p10600	COG0183	Belongs to the thiolase family
ACGSH8M1_p10610	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ACGSH8M1_p10640	COG0783	Belongs to the Dps family
ACGSH8M1_p10800	COG0038	chloride channel
ACGSH8M1_p10830	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ACGSH8M1_p10870	COG0840	transmembrane signaling receptor activity
ACGSH8M1_p10890	COG3385	transposase activity
ACGSH8M1_p10930	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ACGSH8M1_p10940	COG1061	Type III restriction enzyme res subunit
ACGSH8M1_p10950	COG1002	Type II restriction enzyme, methylase subunits
ACGSH8M1_p10980	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACGSH8M1_p11110	COG0640	Transcriptional regulator
ACGSH8M1_p11170	COG4974	Belongs to the 'phage' integrase family
ACGSH8M1_p11320	COG2801	Transposase and inactivated derivatives
ACGSH8M1_p11480	COG4584	PFAM Integrase catalytic
ACGSH8M1_p11490	COG1484	DNA-dependent DNA replication
ACGSH8M1_p11530	COG2801	Transposase and inactivated derivatives
ACGSH8M1_p20090	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ACGSH8M1_p20130	COG1192	Involved in chromosome partitioning
ACGSH8M1_p20140	COG3316	Transposase and inactivated derivatives
ACGSH8M1_p20150	COG3173	Aminoglycoside phosphotransferase
ACGSH8M1_p20190	COG3316	Transposase and inactivated derivatives
ACGSH8M1_p20210	COG3041	Addiction module toxin RelE StbE family
ACGSH8M1_p20270	COG2608	mercury ion transmembrane transporter activity
ACGSH8M1_p20330	COG5002	protein histidine kinase activity
ACGSH8M1_p20330	COG2176	DNA-directed DNA polymerase activity
ACGSH8M1_p20540	COG3385	transposase activity
ACGSH8M1_p20600	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACGSH8M1_p20610	COG0625	glutathione transferase activity
ACGSH8M1_p20660	COG1192	Involved in chromosome partitioning
ACGSH8M1_p30080	COG1192	Involved in chromosome partitioning