locus-tag	class	description
KAM329_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KAM329_00020	COG0592	DNA-directed DNA polymerase activity
KAM329_00040	COG0187	DNA topoisomerase II activity
KAM329_00050	COG2207	Transcriptional regulator
KAM329_00060	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KAM329_00070	COG0071	Belongs to the small heat shock protein (HSP20) family
KAM329_00080	COG0071	Belongs to the small heat shock protein (HSP20) family
KAM329_00090	COG3977	Valine--pyruvate aminotransferase
KAM329_00120	COG2814	Major facilitator Superfamily
KAM329_00130	COG0745	RESPONSE REGULATOR receiver
KAM329_00140	COG2205	protein histidine kinase activity
KAM329_00180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KAM329_00190	COG4191	Histidine kinase
KAM329_00190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM329_00200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM329_00210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM329_00220	COG1309	transcriptional regulator
KAM329_00240	COG0561	phosphatase activity
KAM329_00250	COG2267	carboxylic ester hydrolase activity
KAM329_00260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KAM329_00270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KAM329_00280	COG1758	RNA polymerase activity
KAM329_00300	COG0859	PFAM glycosyl transferase family 9
KAM329_00310	COG3642	lipopolysaccharide core region biosynthetic process
KAM329_00400	COG3335	DDE superfamily endonuclease
KAM329_00410	COG0589	response to stress
KAM329_00430	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KAM329_00440	COG3706	GGDEF domain
KAM329_00450	COG1528	Iron-storage protein
KAM329_00460	COG2081	HI0933 family
KAM329_00470	COG2223	nitrite transmembrane transporter activity
KAM329_00480	COG1280	lysine exporter protein (LysE YggA)
KAM329_00510	COG3188	usher protein
KAM329_00540	COG2197	response regulator
KAM329_00550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM329_00550	COG2205	protein histidine kinase activity
KAM329_00570	COG3275	phosphorelay sensor kinase activity
KAM329_00580	COG3279	Response regulator of the LytR AlgR family
KAM329_00590	COG2223	nitrite transmembrane transporter activity
KAM329_00600	COG3385	transposase activity
KAM329_00610	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KAM329_00620	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KAM329_00660	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KAM329_00670	COG2166	iron-sulfur cluster assembly
KAM329_00680	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KAM329_00720	COG1063	alcohol dehydrogenase
KAM329_00750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KAM329_00840	COG1609	Transcriptional regulator
KAM329_00880	COG1580	Controls the rotational direction of flagella during chemotaxis
KAM329_00890	COG3161	chorismate lyase activity
KAM329_00900	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KAM329_00910	COG2937	Belongs to the GPAT DAPAT family
KAM329_00920	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KAM329_00950	COG0534	Mate efflux family protein
KAM329_00960	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KAM329_00970	COG2205	protein histidine kinase activity
KAM329_00980	COG0745	RESPONSE REGULATOR receiver
KAM329_01000	COG1045	serine acetyltransferase
KAM329_01020	COG3074	FtsZ-dependent cytokinesis
KAM329_01030	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
KAM329_01040	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KAM329_01040	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KAM329_01050	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KAM329_01060	COG1609	Transcriptional regulator
KAM329_01070	COG3250	beta-galactosidase activity
KAM329_01080	COG2731	YhcH YjgK YiaL family protein
KAM329_01090	COG0531	amino acid
KAM329_01100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM329_01110	COG0531	amino acid
KAM329_01120	COG0385	Bile acid
KAM329_01130	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KAM329_01180	COG0583	DNA-binding transcription factor activity
KAM329_01190	COG1079	Belongs to the binding-protein-dependent transport system permease family
KAM329_01210	COG4603	Belongs to the binding-protein-dependent transport system permease family
KAM329_01220	COG3845	ABC transporter
KAM329_01230	COG1744	ABC transporter substrate-binding protein PnrA-like
KAM329_01260	COG0210	DNA helicase
KAM329_01290	COG1943	Transposase
KAM329_01300	COG0583	DNA-binding transcription factor activity
KAM329_01400	COG1280	lysine exporter protein (LysE YggA)
KAM329_01420	COG2962	Rard protein
KAM329_01440	COG1012	belongs to the aldehyde dehydrogenase family
KAM329_01450	COG1396	sequence-specific DNA binding
KAM329_01460	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KAM329_01480	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KAM329_01480	COG0519	Catalyzes the synthesis of GMP from XMP
KAM329_01500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM329_01540	COG1322	Protein conserved in bacteria
KAM329_01550	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KAM329_01560	COG0569	domain protein
KAM329_01570	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KAM329_01570	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KAM329_01580	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KAM329_01590	COG0242	peptide deformylase activity
KAM329_01610	COG0758	DNA mediated transformation
KAM329_01620	COG2922	Belongs to the Smg family
KAM329_01630	COG0551	DNA topoisomerase type I activity
KAM329_01640	COG0009	L-threonylcarbamoyladenylate synthase
KAM329_01650	COG0408	coproporphyrinogen oxidase activity
KAM329_01660	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KAM329_01680	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KAM329_01710	COG3078	GTPase activator activity
KAM329_01730	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KAM329_01750	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KAM329_01770	COG3852	Histidine kinase
KAM329_01790	COG0174	glutamine synthetase
KAM329_01800	COG1217	gtp-binding protein TYPA
KAM329_01820	COG1295	ribonuclease BN
KAM329_01830	COG1490	D-aminoacyl-tRNA deacylase activity
KAM329_01860	COG0456	acetyltransferase
KAM329_01880	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KAM329_01890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KAM329_01900	COG2610	gluconate transmembrane transporter activity
KAM329_01910	COG3265	gluconokinase activity
KAM329_01920	COG0129	dihydroxy-acid dehydratase activity
KAM329_01930	COG0800	Aldolase
KAM329_01960	COG1609	Transcriptional regulator
KAM329_01980	COG4942	peptidase
KAM329_01990	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KAM329_02000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KAM329_02010	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KAM329_02020	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KAM329_02030	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KAM329_02030	COG0316	Belongs to the HesB IscA family
KAM329_02040	COG1040	competence protein
KAM329_02050	COG0596	Alpha beta hydrolase
KAM329_02080	COG2183	response to ionizing radiation
KAM329_02090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KAM329_02110	COG2205	protein histidine kinase activity
KAM329_02130	COG0051	transcription antitermination factor activity, RNA binding
KAM329_02140	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KAM329_02150	COG0088	Forms part of the polypeptide exit tunnel
KAM329_02160	COG0089	rRNA binding
KAM329_02170	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KAM329_02180	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KAM329_02190	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KAM329_02200	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KAM329_02210	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KAM329_02220	COG0255	Belongs to the universal ribosomal protein uL29 family
KAM329_02230	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KAM329_02240	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KAM329_02250	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KAM329_02260	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KAM329_02270	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KAM329_02280	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KAM329_02290	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KAM329_02300	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KAM329_02310	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KAM329_02320	COG1841	ribosomal large subunit assembly
KAM329_02330	COG0200	Binds to the 23S rRNA
KAM329_02340	COG0201	protein transport
KAM329_02350	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KAM329_02360	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KAM329_02370	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KAM329_02380	COG0202	RNA polymerase activity
KAM329_02390	COG0203	ribosomal protein L17
KAM329_02420	COG3335	DDE superfamily endonuclease
KAM329_02430	COG1484	DNA-dependent DNA replication
KAM329_02440	COG1484	DNA-dependent DNA replication
KAM329_02450	COG4584	PFAM Integrase catalytic
KAM329_02470	COG4584	PFAM Integrase catalytic
KAM329_02530	COG2249	NAD(P)H dehydrogenase (quinone) activity
KAM329_02540	COG0583	DNA-binding transcription factor activity
KAM329_02560	COG0675	Transposase, IS605 OrfB family
KAM329_02570	COG4221	oxidoreductase activity
KAM329_02600	COG1770	oligopeptidase
KAM329_02610	COG2358	TRAP transporter, solute receptor (TAXI family
KAM329_02640	COG3714	YhhN family
KAM329_02670	COG0583	DNA-binding transcription factor activity
KAM329_02700	COG1301	dicarboxylic acid transport
KAM329_02720	COG2095	MarC family integral membrane protein
KAM329_02740	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KAM329_02760	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KAM329_02770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KAM329_02830	COG0742	ribosomal rna small subunit methyltransferase
KAM329_02840	COG0552	protein localization to endoplasmic reticulum
KAM329_02850	COG2884	Cell division ATP-binding protein ftsE
KAM329_02860	COG2177	Part of the ABC transporter FtsEX involved in
KAM329_02880	COG0288	reversible hydration of carbon dioxide
KAM329_02890	COG2188	Transcriptional regulator
KAM329_02900	COG1228	amidohydrolase
KAM329_02910	COG0010	Belongs to the arginase family
KAM329_02920	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KAM329_02930	COG2986	histidine ammonia-lyase
KAM329_02940	COG0387	Pfam Sodium calcium exchanger
KAM329_02950	COG2200	EAL domain
KAM329_03050	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KAM329_03060	COG1459	type II secretion system
KAM329_03080	COG2165	general secretion pathway protein
KAM329_03090	COG2165	general secretion pathway protein
KAM329_03150	COG1077	Cell shape determining protein MreB Mrl
KAM329_03160	COG1792	Involved in formation and maintenance of cell shape
KAM329_03170	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KAM329_03180	COG0424	maF-like protein
KAM329_03190	COG1530	ribonuclease E activity
KAM329_03200	COG3164	Protein of unknown function
KAM329_03220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KAM329_03230	COG0312	modulator of DNA gyrase
KAM329_03260	COG0477	Major facilitator Superfamily
KAM329_03280	COG2321	neutral zinc metallopeptidase
KAM329_03300	COG0675	Transposase, IS605 OrfB family
KAM329_03370	COG0189	ligase activity
KAM329_03380	COG0642	Histidine kinase
KAM329_03390	COG0745	RESPONSE REGULATOR receiver
KAM329_03420	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KAM329_03430	COG0352	thiamine-phosphate diphosphorylase activity
KAM329_03440	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KAM329_03460	COG2022	thiamine diphosphate biosynthetic process
KAM329_03470	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KAM329_03500	COG3932	Exopolysaccharide synthesis, ExoD
KAM329_03540	COG1733	regulation of RNA biosynthetic process
KAM329_03550	COG0456	acetyltransferase
KAM329_03610	COG2226	methyltransferase
KAM329_03630	COG1494	fructose-1,6-bisphosphatase
KAM329_03650	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KAM329_03660	COG5007	Belongs to the BolA IbaG family
KAM329_03680	COG2854	intermembrane phospholipid transfer
KAM329_03690	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KAM329_03700	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KAM329_03710	COG1127	ABC transporter
KAM329_03720	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KAM329_03720	COG0517	IMP dehydrogenase activity
KAM329_03730	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KAM329_03750	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KAM329_03760	COG1137	ATPase activity
KAM329_03770	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KAM329_03790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM329_03800	COG1660	Displays ATPase and GTPase activities
KAM329_03810	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM329_03850	COG3964	amidohydrolase
KAM329_03910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KAM329_03920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KAM329_03940	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KAM329_03950	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KAM329_03960	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KAM329_03970	COG0723	plastoquinol--plastocyanin reductase activity
KAM329_03980	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KAM329_03990	COG2857	Cytochrome c1
KAM329_04000	COG0625	glutathione transferase activity
KAM329_04010	COG2969	positive regulation of protein catabolic process
KAM329_04030	COG2823	Periplasmic or secreted lipoprotein
KAM329_04040	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KAM329_04050	COG0792	nuclease activity
KAM329_04060	COG3107	peptidoglycan biosynthetic process
KAM329_04070	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KAM329_04080	COG2001	Belongs to the MraZ family
KAM329_04090	COG0275	rRNA processing
KAM329_04100	COG3116	cell division
KAM329_04110	COG0768	penicillin binding
KAM329_04120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KAM329_04130	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KAM329_04140	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KAM329_04150	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KAM329_04160	COG0772	Belongs to the SEDS family
KAM329_04170	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KAM329_04180	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KAM329_04190	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KAM329_04200	COG0849	cell division
KAM329_04210	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KAM329_04220	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KAM329_04240	COG0653	protein targeting
KAM329_04260	COG0494	nUDIX hydrolase
KAM329_04270	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KAM329_04280	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
KAM329_04310	COG1459	type II secretion system
KAM329_04320	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KAM329_04380	COG2186	Transcriptional regulator
KAM329_04390	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KAM329_04400	COG0508	dehydrogenase complex catalyzes the overall conversion of
KAM329_04410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KAM329_04430	COG0840	transmembrane signaling receptor activity
KAM329_04440	COG1752	Esterase of the alpha-beta hydrolase superfamily
KAM329_04450	COG1049	propionate catabolic process, 2-methylcitrate cycle
KAM329_04460	COG2200	EAL domain
KAM329_04470	COG2200	EAL domain
KAM329_04470	COG2771	luxR family
KAM329_04500	COG1280	lysine exporter protein (LysE YggA)
KAM329_04520	COG0523	cobalamin synthesis protein
KAM329_04550	COG0477	Major facilitator Superfamily
KAM329_04580	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KAM329_04590	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KAM329_04600	COG3335	DDE superfamily endonuclease
KAM329_04660	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KAM329_04680	COG1546	Belongs to the CinA family
KAM329_04690	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KAM329_04700	COG2137	regulation of response to DNA damage stimulus
KAM329_04710	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KAM329_04720	COG0527	aspartate kinase activity
KAM329_04730	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KAM329_04740	COG1686	Belongs to the peptidase S11 family
KAM329_04750	COG0586	Pfam SNARE associated Golgi protein
KAM329_04760	COG1253	flavin adenine dinucleotide binding
KAM329_04770	COG0525	valine-tRNA ligase activity
KAM329_04790	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KAM329_04800	COG0795	lipopolysaccharide-transporting ATPase activity
KAM329_04810	COG0795	lipopolysaccharide-transporting ATPase activity
KAM329_04830	COG0582	viral genome integration into host DNA
KAM329_04960	COG1196	nuclear chromosome segregation
KAM329_05010	COG2801	Transposase and inactivated derivatives
KAM329_05070	COG0004	ammonium transporteR
KAM329_05080	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KAM329_05110	COG2165	general secretion pathway protein
KAM329_05120	COG0084	hydrolase, TatD family'
KAM329_05130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KAM329_05150	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KAM329_05160	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KAM329_05170	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KAM329_05180	COG0813	purine-nucleoside phosphorylase activity
KAM329_05190	COG3447	MASE1 domain protein
KAM329_05190	COG5001	Diguanylate cyclase
KAM329_05190	COG5002	protein histidine kinase activity
KAM329_05210	COG0560	Phosphoserine phosphatase
KAM329_05230	COG3385	transposase activity
KAM329_05250	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KAM329_05270	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
KAM329_05280	COG0776	regulation of translation
KAM329_05310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KAM329_05320	COG0735	belongs to the Fur family
KAM329_05360	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KAM329_05370	COG0513	Belongs to the DEAD box helicase family
KAM329_05380	COG3022	response to hydroperoxide
KAM329_05410	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KAM329_05420	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KAM329_05430	COG0762	integral membrane protein
KAM329_05440	COG1872	DUF167
KAM329_05480	COG3112	Uncharacterised protein family (UPF0231)
KAM329_05490	COG3835	regulator
KAM329_05500	COG2610	gluconate transmembrane transporter activity
KAM329_05510	COG1929	Belongs to the glycerate kinase type-1 family
KAM329_05540	COG0583	DNA-binding transcription factor activity
KAM329_05550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KAM329_05580	COG0347	Belongs to the P(II) protein family
KAM329_05610	COG3842	ATPase activity
KAM329_05620	COG2837	iron assimilation
KAM329_05630	COG1438	arginine binding
KAM329_05640	COG1126	abc transporter atp-binding protein
KAM329_05650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM329_05660	COG4215	(ABC) transporter
KAM329_05670	COG4160	amino acid transport
KAM329_05680	COG0039	L-malate dehydrogenase activity
KAM329_05700	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
KAM329_05710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KAM329_05710	COG1017	nitric oxide dioxygenase activity
KAM329_05730	COG4536	flavin adenine dinucleotide binding
KAM329_05740	COG4137	Cytochrome C assembly protein
KAM329_05750	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KAM329_05760	COG0228	four-way junction DNA binding
KAM329_05770	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KAM329_05780	COG0336	Belongs to the RNA methyltransferase TrmD family
KAM329_05790	COG0335	large ribosomal subunit rRNA binding
KAM329_05820	COG1051	belongs to the nudix hydrolase family
KAM329_05840	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KAM329_05850	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KAM329_05860	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KAM329_05880	COG0583	DNA-binding transcription factor activity
KAM329_05890	COG0640	Transcriptional regulator
KAM329_05900	COG0268	Binds directly to 16S ribosomal RNA
KAM329_05910	COG0728	peptidoglycan biosynthetic process
KAM329_05920	COG0196	riboflavin kinase activity
KAM329_05930	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KAM329_05940	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KAM329_05950	COG1047	Peptidyl-prolyl cis-trans
KAM329_05960	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KAM329_06020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KAM329_06020	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KAM329_06050	COG1854	S-ribosylhomocysteine lyase activity
KAM329_06060	COG3706	GGDEF domain
KAM329_06070	COG0557	exoribonuclease II activity
KAM329_06080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KAM329_06100	COG2153	protein acetylation
KAM329_06120	COG1914	H( )-stimulated, divalent metal cation uptake system
KAM329_06130	COG0360	Binds together with S18 to 16S ribosomal RNA
KAM329_06140	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KAM329_06150	COG0359	binds to the 23S rRNA
KAM329_06230	COG1238	metal cluster binding
KAM329_06240	COG0612	Peptidase, M16
KAM329_06250	COG2918	glutathione biosynthetic process
KAM329_06260	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KAM329_06270	COG1027	Aspartate ammonia-lyase
KAM329_06280	COG3030	protein affecting phage T7 exclusion by the F plasmid
KAM329_06290	COG0534	Mate efflux family protein
KAM329_06310	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KAM329_06320	COG0459	protein refolding
KAM329_06360	COG0564	pseudouridine synthase activity
KAM329_06370	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KAM329_06380	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KAM329_06410	COG3335	DDE superfamily endonuclease
KAM329_06420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KAM329_06430	COG4208	sulfate ABC transporter
KAM329_06440	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KAM329_06450	COG0583	DNA-binding transcription factor activity
KAM329_06460	COG3397	chitin binding
KAM329_06470	COG0840	transmembrane signaling receptor activity
KAM329_06520	COG1328	CTP reductase activity
KAM329_06530	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KAM329_06560	COG1448	Aminotransferase
KAM329_06570	COG2194	sulfuric ester hydrolase activity
KAM329_06610	COG1215	transferase activity, transferring glycosyl groups
KAM329_06620	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KAM329_06630	COG3118	belongs to the thioredoxin family
KAM329_06630	COG0457	Tetratricopeptide repeat
KAM329_06700	COG0513	Belongs to the DEAD box helicase family
KAM329_06710	COG0840	transmembrane signaling receptor activity
KAM329_06730	COG4166	transmembrane transport
KAM329_06760	COG1024	Enoyl-CoA hydratase
KAM329_06790	COG4221	oxidoreductase activity
KAM329_06800	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KAM329_06810	COG0442	prolyl-tRNA aminoacylation
KAM329_06820	COG0840	transmembrane signaling receptor activity
KAM329_06830	COG0632	four-way junction helicase activity
KAM329_06840	COG2255	four-way junction helicase activity
KAM329_06850	COG1271	oxidase subunit
KAM329_06860	COG1294	oxidase, subunit
KAM329_06870	COG3790	cyd operon protein YbgE
KAM329_06880	COG0824	Thioesterase
KAM329_06890	COG0811	peptide transport
KAM329_06920	COG0823	Involved in the tonB-independent uptake of proteins
KAM329_06930	COG2885	chlorophyll binding
KAM329_06940	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
KAM329_06950	COG0840	transmembrane signaling receptor activity
KAM329_06960	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KAM329_06980	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KAM329_06990	COG1640	4-alpha-glucanotransferase
KAM329_07000	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KAM329_07060	COG2130	NADP-dependent
KAM329_07070	COG1846	Transcriptional regulator
KAM329_07130	COG0561	phosphatase activity
KAM329_07160	COG0733	neurotransmitter:sodium symporter activity
KAM329_07170	COG0733	neurotransmitter:sodium symporter activity
KAM329_07200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KAM329_07230	COG1794	racemase activity, acting on amino acids and derivatives
KAM329_07250	COG1022	Amp-dependent synthetase and ligase
KAM329_07270	COG0456	acetyltransferase
KAM329_07300	COG2425	protein containing a von Willebrand factor type A (vWA) domain
KAM329_07310	COG5001	Diguanylate cyclase
KAM329_07310	COG5002	protein histidine kinase activity
KAM329_07330	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KAM329_07350	COG0456	acetyltransferase
KAM329_07370	COG0456	acetyltransferase
KAM329_07380	COG1902	pentaerythritol trinitrate reductase activity
KAM329_07400	COG2852	Protein conserved in bacteria
KAM329_07420	COG2957	Belongs to the agmatine deiminase family
KAM329_07430	COG0154	amidase activity
KAM329_07500	COG2207	Transcriptional regulator
KAM329_07500	COG1917	Cupin 2, conserved barrel domain protein
KAM329_07520	COG0513	Belongs to the DEAD box helicase family
KAM329_07530	COG2203	Gaf domain
KAM329_07530	COG2199	diguanylate cyclase activity
KAM329_07610	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
KAM329_07630	COG0577	efflux transmembrane transporter activity
KAM329_07630	COG1136	(ABC) transporter
KAM329_07640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM329_07650	COG0745	RESPONSE REGULATOR receiver
KAM329_07660	COG2205	protein histidine kinase activity
KAM329_07720	COG1280	lysine exporter protein (LysE YggA)
KAM329_07730	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KAM329_07740	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KAM329_07760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM329_07820	COG0745	RESPONSE REGULATOR receiver
KAM329_07830	COG3104	oligopeptide transport
KAM329_07840	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KAM329_07850	COG1555	photosystem II stabilization
KAM329_07870	COG3385	transposase activity
KAM329_07880	COG2350	Protein conserved in bacteria
KAM329_07890	COG2917	probably involved in intracellular septation
KAM329_07900	COG0076	glutamate decarboxylase activity
KAM329_07910	COG1272	protein, Hemolysin III
KAM329_07920	COG0569	domain protein
KAM329_07920	COG2985	domain, Protein
KAM329_07940	COG0477	Major facilitator Superfamily
KAM329_07950	COG0583	DNA-binding transcription factor activity
KAM329_07960	COG3227	Zinc metalloprotease (Elastase)
KAM329_07970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KAM329_07980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KAM329_08000	COG2731	YhcH YjgK YiaL family protein
KAM329_08020	COG0668	transmembrane transport
KAM329_08040	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KAM329_08060	COG0789	Transcriptional regulator
KAM329_08150	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KAM329_08170	COG0488	(ABC) transporter
KAM329_08180	COG0517	IMP dehydrogenase activity
KAM329_08180	COG0516	GMP reductase activity
KAM329_08200	COG0835	chemotaxis
KAM329_08200	COG0784	Response regulator, receiver
KAM329_08210	COG2755	lipolytic protein G-D-S-L family
KAM329_08220	COG4181	ATPase activity
KAM329_08230	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KAM329_08240	COG1090	epimerase
KAM329_08250	COG2200	EAL domain
KAM329_08260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KAM329_08270	COG4935	Belongs to the peptidase S8 family
KAM329_08270	COG2234	aminopeptidase activity
KAM329_08280	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KAM329_08290	COG3171	Protein conserved in bacteria
KAM329_08300	COG2066	Belongs to the glutaminase family
KAM329_08310	COG2897	thiosulfate sulfurtransferase activity
KAM329_08330	COG1132	(ABC) transporter
KAM329_08360	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
KAM329_08370	COG3300	MHYT domain
KAM329_08370	COG5001	Diguanylate cyclase
KAM329_08410	COG4628	conserved protein (DUF2132)
KAM329_08420	COG0688	phosphatidylethanolamine metabolic process
KAM329_08430	COG1162	GTPase activity
KAM329_08440	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KAM329_08450	COG3335	DDE superfamily endonuclease
KAM329_08470	COG1278	Cold shock
KAM329_08490	COG0840	transmembrane signaling receptor activity
KAM329_08500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KAM329_08550	COG0848	biopolymer transport protein
KAM329_08560	COG0811	peptide transport
KAM329_08570	COG0811	peptide transport
KAM329_08590	COG4206	TonB-dependent receptor
KAM329_08600	COG4174	ABC transporter (Permease)
KAM329_08610	COG4239	(ABC) transporter, permease
KAM329_08630	COG0444	Belongs to the ABC transporter superfamily
KAM329_08640	COG4608	Belongs to the ABC transporter superfamily
KAM329_08660	COG2195	Cleaves the N-terminal amino acid of tripeptides
KAM329_08670	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
KAM329_08680	COG1073	alpha beta
KAM329_08710	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KAM329_08760	COG0243	molybdopterin cofactor binding
KAM329_08770	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KAM329_08770	COG1648	precorrin-2 dehydrogenase activity
KAM329_08790	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KAM329_08790	COG1116	anion transmembrane transporter activity
KAM329_08800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KAM329_08810	COG1116	anion transmembrane transporter activity
KAM329_08820	COG2146	nitrite reductase [NAD(P)H] activity
KAM329_08820	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KAM329_08830	COG2146	nitrite reductase [NAD(P)H] activity
KAM329_08830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KAM329_08840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM329_08850	COG2313	pseudouridylate synthase activity
KAM329_08890	COG0521	Mo-molybdopterin cofactor biosynthetic process
KAM329_08910	COG2966	Psort location CytoplasmicMembrane, score
KAM329_08940	COG4175	Glycine betaine
KAM329_08950	COG4176	ABC-type proline glycine betaine transport system permease component
KAM329_08960	COG2113	Glycine betaine
KAM329_08970	COG0175	sulfate reduction
KAM329_08980	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KAM329_08990	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KAM329_09010	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KAM329_09020	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KAM329_09040	COG0786	glutamate:sodium symporter activity
KAM329_09050	COG0252	asparaginase activity
KAM329_09060	COG3139	Protein of unknown function (DUF1315)
KAM329_09100	COG0616	signal peptide processing
KAM329_09110	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAM329_09110	COG1902	pentaerythritol trinitrate reductase activity
KAM329_09120	COG0778	Nitroreductase
KAM329_09140	COG0110	maltose O-acetyltransferase activity
KAM329_09150	COG2264	protein methyltransferase activity
KAM329_09160	COG0604	alcohol dehydrogenase
KAM329_09170	COG0583	DNA-binding transcription factor activity
KAM329_09180	COG1263	PTS System
KAM329_09180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM329_09180	COG2190	(PTS) system
KAM329_09190	COG4145	pantothenate transmembrane transporter activity
KAM329_09200	COG3924	membrane
KAM329_09210	COG0439	Biotin carboxylase
KAM329_09220	COG0511	ligase activity, forming carbon-carbon bonds
KAM329_09230	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KAM329_09240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KAM329_09270	COG3381	protein complex oligomerization
KAM329_09290	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KAM329_09310	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KAM329_09320	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KAM329_09320	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KAM329_09350	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KAM329_09360	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KAM329_09370	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KAM329_09380	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KAM329_09390	COG4172	Belongs to the ABC transporter superfamily
KAM329_09410	COG0601	transmembrane transport
KAM329_09420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAM329_09430	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KAM329_09440	COG0142	geranyltranstransferase activity
KAM329_09450	COG1722	exodeoxyribonuclease VII activity
KAM329_09460	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KAM329_09470	COG1360	Flagellar Motor Protein
KAM329_09500	COG1534	Rna-binding protein
KAM329_09510	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KAM329_09530	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KAM329_09540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KAM329_09550	COG0149	triose-phosphate isomerase activity
KAM329_09560	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KAM329_09570	COG0779	Required for maturation of 30S ribosomal subunits
KAM329_09580	COG0195	Participates in both transcription termination and antitermination
KAM329_09590	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KAM329_09600	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KAM329_09610	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KAM329_09620	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KAM329_09630	COG1185	polyribonucleotide nucleotidyltransferase activity
KAM329_09640	COG2211	Major facilitator Superfamily
KAM329_09650	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KAM329_09660	COG1422	Protein of unknown function (DUF1090)
KAM329_09670	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KAM329_09680	COG0826	peptidase U32
KAM329_09720	COG0312	modulator of DNA gyrase
KAM329_09730	COG0312	modulator of DNA gyrase
KAM329_09750	COG4974	Belongs to the 'phage' integrase family
KAM329_09760	COG1970	mechanosensitive ion channel activity
KAM329_09790	COG0789	Transcriptional regulator
KAM329_09820	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM329_09840	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KAM329_09850	COG0321	lipoyl(octanoyl) transferase activity
KAM329_09860	COG2921	Belongs to the UPF0250 family
KAM329_09870	COG1686	Belongs to the peptidase S11 family
KAM329_09880	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KAM329_09890	COG2951	lytic endotransglycosylase activity
KAM329_09900	COG0772	Belongs to the SEDS family
KAM329_09910	COG0768	penicillin binding
KAM329_09920	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KAM329_09930	COG0799	negative regulation of ribosome biogenesis
KAM329_09940	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KAM329_09980	COG0495	leucyl-tRNA aminoacylation
KAM329_09990	COG2888	peptidyl-tyrosine sulfation
KAM329_10000	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KAM329_10010	COG4535	Mg2 and Co2 transporter CorC
KAM329_10020	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KAM329_10030	COG1702	phosphate starvation-inducible protein PhoH
KAM329_10040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KAM329_10050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KAM329_10060	COG1335	isochorismatase
KAM329_10070	COG1278	Cold shock
KAM329_10100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAM329_10110	COG2199	diguanylate cyclase activity
KAM329_10130	COG2199	diguanylate cyclase activity
KAM329_10150	COG3385	transposase activity
KAM329_10160	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KAM329_10190	COG1464	Belongs to the NlpA lipoprotein family
KAM329_10200	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KAM329_10210	COG2011	ABC-type metal ion transport system permease component
KAM329_10220	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KAM329_10240	COG0516	GMP reductase activity
KAM329_10250	COG4067	protein conserved in archaea
KAM329_10250	COG0189	ligase activity
KAM329_10290	COG0300	oxidoreductase activity
KAM329_10330	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KAM329_10340	COG3214	Protein conserved in bacteria
KAM329_10370	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
KAM329_10380	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
KAM329_10390	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KAM329_10400	COG1053	succinate dehydrogenase
KAM329_10420	COG0584	glycerophosphoryl diester phosphodiesterase
KAM329_10430	COG1511	domain protein
KAM329_10430	COG3264	Mechanosensitive ion channel
KAM329_10450	COG0739	heme binding
KAM329_10480	COG0583	DNA-binding transcription factor activity
KAM329_10510	COG0583	DNA-binding transcription factor activity
KAM329_10520	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KAM329_10590	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KAM329_10600	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KAM329_10620	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KAM329_10630	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KAM329_10640	COG0546	phosphoglycolate phosphatase activity
KAM329_10650	COG0180	Tryptophanyl-tRNA synthetase
KAM329_10680	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KAM329_10700	COG1012	belongs to the aldehyde dehydrogenase family
KAM329_10720	COG3385	transposase activity
KAM329_10730	COG2801	Transposase and inactivated derivatives
KAM329_10740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAM329_10770	COG0657	acetylesterase activity
KAM329_10790	COG0471	metal ion transport
KAM329_10790	COG0490	domain, Protein
KAM329_10800	COG0012	GTP binding
KAM329_10810	COG0193	aminoacyl-tRNA hydrolase activity
KAM329_10820	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KAM329_10830	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KAM329_10840	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KAM329_10850	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KAM329_10860	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KAM329_10870	COG2890	protein-(glutamine-N5) methyltransferase activity
KAM329_10890	COG2912	Transglutaminase-like superfamily
KAM329_10900	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KAM329_10910	COG1301	dicarboxylic acid transport
KAM329_10930	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KAM329_10960	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KAM329_10970	COG1115	amino acid carrier protein
KAM329_11010	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KAM329_11030	COG0189	ligase activity
KAM329_11040	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KAM329_11060	COG3091	SprT-like family
KAM329_11080	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KAM329_11100	COG2801	Transposase and inactivated derivatives
KAM329_11140	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KAM329_11150	COG0739	heme binding
KAM329_11160	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KAM329_11170	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
KAM329_11170	COG3408	Glycogen debranching enzyme
KAM329_11190	COG1881	PFAM PEBP family protein
KAM329_11200	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KAM329_11210	COG0583	DNA-binding transcription factor activity
KAM329_11230	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KAM329_11250	COG0583	DNA-binding transcription factor activity
KAM329_11260	COG1028	Short-chain dehydrogenase reductase Sdr
KAM329_11270	COG0616	signal peptide processing
KAM329_11280	COG3724	N-succinylarginine dihydrolase activity
KAM329_11320	COG0840	transmembrane signaling receptor activity
KAM329_11350	COG2971	BadF BadG BcrA BcrD
KAM329_11370	COG4608	Belongs to the ABC transporter superfamily
KAM329_11380	COG0444	Belongs to the ABC transporter superfamily
KAM329_11390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAM329_11420	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KAM329_11430	COG3039	Transposase
KAM329_11480	COG3328	transposase activity
KAM329_11500	COG2801	Transposase and inactivated derivatives
KAM329_11520	COG3039	Transposase
KAM329_11570	COG3039	Transposase
KAM329_11590	COG2801	Transposase and inactivated derivatives
KAM329_11630	COG0640	Transcriptional regulator
KAM329_11640	COG0798	PFAM Bile acid sodium symporter
KAM329_11650	COG1393	Belongs to the ArsC family
KAM329_11680	COG1677	Flagellar hook-basal body complex protein FliE
KAM329_11700	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KAM329_11810	COG1684	flagellar biosynthetic protein fliR
KAM329_11830	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KAM329_11880	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KAM329_11890	COG0784	Response regulator, receiver
KAM329_11890	COG2198	Histidine kinase
KAM329_11890	COG0643	Histidine kinase
KAM329_11910	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KAM329_11920	COG1360	Flagellar Motor Protein
KAM329_11930	COG1192	Involved in chromosome partitioning
KAM329_11950	COG0835	chemotaxis
KAM329_11980	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KAM329_11990	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KAM329_12000	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KAM329_12010	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KAM329_12020	COG1138	Cytochrome C-type biogenesis protein
KAM329_12030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KAM329_12050	COG0457	Tetratricopeptide repeat
KAM329_12080	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KAM329_12090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KAM329_12090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KAM329_12120	COG0259	pyridoxamine-phosphate oxidase activity
KAM329_12180	COG3153	acetyltransferase
KAM329_12210	COG0800	Aldolase
KAM329_12220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM329_12240	COG2721	sulfolactate sulfo-lyase activity
KAM329_12250	COG0246	Mannitol dehydrogenase
KAM329_12310	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KAM329_12370	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KAM329_12390	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KAM329_12440	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KAM329_12450	COG2003	Belongs to the UPF0758 family
KAM329_12460	COG3039	Transposase
KAM329_12500	COG3039	Transposase
KAM329_12510	COG2850	peptidyl-arginine hydroxylation
KAM329_12530	COG4122	O-methyltransferase activity
KAM329_12560	COG0210	DNA helicase
KAM329_12560	COG0210	DNA helicase
KAM329_12630	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KAM329_12640	COG2867	negative regulation of translational initiation
KAM329_12650	COG2914	Belongs to the UPF0125 (RnfH) family
KAM329_12660	COG0702	epimerase
KAM329_12670	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAM329_12680	COG1454	alcohol dehydrogenase
KAM329_12700	COG0564	pseudouridine synthase activity
KAM329_12710	COG1957	nucleoside hydrolase
KAM329_12770	COG1280	lysine exporter protein (LysE YggA)
KAM329_12790	COG3263	regulation of cellular component size
KAM329_12810	COG1876	peptidase activity
KAM329_12820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KAM329_12830	COG1393	Belongs to the ArsC family
KAM329_12840	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM329_12870	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM329_12920	COG5433	transposase activity
KAM329_12930	COG3069	C4-dicarboxylate transmembrane transporter activity
KAM329_12940	COG1473	amidohydrolase
KAM329_12960	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KAM329_12970	COG0017	Asparaginyl-tRNA synthetase
KAM329_13020	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KAM329_13030	COG0156	8-amino-7-oxononanoate synthase activity
KAM329_13040	COG2226	methyltransferase
KAM329_13040	COG1073	alpha beta
KAM329_13050	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KAM329_13060	COG0501	Belongs to the peptidase M48B family
KAM329_13070	COG0633	Ferredoxin
KAM329_13070	COG3217	Mosc domain protein beta barrel domain protein
KAM329_13070	COG3217	Mosc domain protein beta barrel domain protein
KAM329_13070	COG0633	Ferredoxin
KAM329_13090	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KAM329_13090	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KAM329_13090	COG0674	pyruvate-flavodoxin oxidoreductase activity
KAM329_13090	COG1013	pyruvate-flavodoxin oxidoreductase activity
KAM329_13100	COG2841	Protein conserved in bacteria
KAM329_13120	COG0534	Mate efflux family protein
KAM329_13190	COG1309	transcriptional regulator
KAM329_13220	COG0791	NLP P60 protein
KAM329_13230	COG0583	DNA-binding transcription factor activity
KAM329_13270	COG0500	methyltransferase
KAM329_13280	COG4106	trans-aconitate 2-methyltransferase activity
KAM329_13290	COG1801	Protein of unknown function DUF72
KAM329_13300	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KAM329_13310	COG0217	transcriptional regulatory protein
KAM329_13320	COG2194	sulfuric ester hydrolase activity
KAM329_13340	COG1846	Transcriptional regulator
KAM329_13340	COG1940	carbohydrate kinase activity
KAM329_13350	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KAM329_13360	COG0363	glucosamine-6-phosphate deaminase activity
KAM329_13370	COG2190	(PTS) system
KAM329_13370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM329_13370	COG1263	PTS System
KAM329_13390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KAM329_13400	COG0735	belongs to the Fur family
KAM329_13420	COG0716	FMN binding
KAM329_13450	COG0596	Alpha beta hydrolase
KAM329_13460	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
KAM329_13470	COG0033	Phosphoglucomutase
KAM329_13490	COG1846	Transcriptional regulator
KAM329_13500	COG2951	lytic endotransglycosylase activity
KAM329_13510	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KAM329_13520	COG4136	ATPase activity
KAM329_13540	COG4134	Bacterial extracellular solute-binding protein
KAM329_13550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KAM329_13560	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KAM329_13580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KAM329_13600	COG0729	surface antigen
KAM329_13610	COG2911	Protein conserved in bacteria
KAM329_13630	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KAM329_13650	COG0741	lytic transglycosylase activity
KAM329_13680	COG1607	acyl-coa hydrolase
KAM329_13780	COG3451	type IV secretory pathway VirB4
KAM329_13800	COG3838	Conjugal transfer protein Trbc
KAM329_13810	COG4962	Type ii secretion system protein e
KAM329_13850	COG0583	DNA-binding transcription factor activity
KAM329_13900	COG2076	Multidrug Resistance protein
KAM329_13940	COG4959	Type IV secretory pathway protease TraF
KAM329_13970	COG1192	Involved in chromosome partitioning
KAM329_14040	COG5489	Protein of unknown function (DUF736)
KAM329_14100	COG2003	Belongs to the UPF0758 family
KAM329_14120	COG4804	nuclease activity
KAM329_14140	COG0741	lytic transglycosylase activity
KAM329_14140	COG1388	LysM domain
KAM329_14150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KAM329_14160	COG2226	methyltransferase
KAM329_14170	COG0328	RNA-DNA hybrid ribonuclease activity
KAM329_14180	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KAM329_14200	COG3437	response regulator, receiver
KAM329_14200	COG0784	Response regulator, receiver
KAM329_14210	COG1960	acyl-CoA dehydrogenase activity
KAM329_14220	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KAM329_14230	COG0121	glutamine amidotransferase
KAM329_14250	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KAM329_14310	COG2197	response regulator
KAM329_14320	COG3850	Histidine kinase
KAM329_14330	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KAM329_14340	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
KAM329_14340	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KAM329_14360	COG0243	molybdopterin cofactor binding
KAM329_14370	COG0437	4 iron, 4 sulfur cluster binding
KAM329_14380	COG0348	domain, Protein
KAM329_14400	COG3005	denitrification pathway
KAM329_14410	COG0521	Mo-molybdopterin cofactor biosynthetic process
KAM329_14420	COG0315	cyclic pyranopterin monophosphate synthase activity
KAM329_14430	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KAM329_14440	COG0314	molybdopterin synthase activity
KAM329_14470	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KAM329_14490	COG3335	DDE superfamily endonuclease
KAM329_14530	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KAM329_14550	COG0302	gtp cyclohydrolase
KAM329_14560	COG0840	transmembrane signaling receptor activity
KAM329_14570	COG0840	transmembrane signaling receptor activity
KAM329_14580	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KAM329_14600	COG0583	DNA-binding transcription factor activity
KAM329_14620	COG3335	DDE superfamily endonuclease
KAM329_14650	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KAM329_14680	COG2195	Cleaves the N-terminal amino acid of tripeptides
KAM329_14690	COG1166	arginine decarboxylase activity
KAM329_14740	COG1403	HNH endonuclease
KAM329_14750	COG5433	transposase activity
KAM329_14790	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KAM329_14800	COG1187	pseudouridine synthase activity
KAM329_14810	COG2807	transmembrane transport
KAM329_14830	COG0583	DNA-binding transcription factor activity
KAM329_14870	COG2979	Protein of unknown function (DUF533)
KAM329_14890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KAM329_14900	COG1271	oxidase subunit
KAM329_14910	COG1294	oxidase, subunit
KAM329_14920	COG2814	Major facilitator Superfamily
KAM329_14930	COG0656	L-ascorbic acid biosynthetic process
KAM329_14970	COG0583	DNA-binding transcription factor activity
KAM329_14980	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KAM329_14990	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KAM329_15000	COG2271	Major facilitator Superfamily
KAM329_15020	COG2271	Major facilitator Superfamily
KAM329_15030	COG1349	DNA-binding transcription factor activity
KAM329_15050	COG0584	glycerophosphoryl diester phosphodiesterase
KAM329_15060	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAM329_15070	COG0287	Prephenate dehydrogenase
KAM329_15070	COG1605	Chorismate mutase
KAM329_15090	COG3085	chromosome segregation
KAM329_15100	COG4574	serine-type endopeptidase inhibitor activity
KAM329_15130	COG0675	Transposase, IS605 OrfB family
KAM329_15150	COG4771	TonB-dependent receptor
KAM329_15160	COG3083	sulfuric ester hydrolase activity
KAM329_15170	COG3082	Protein of unknown function (DUF1414)
KAM329_15180	COG3081	Nucleoid-associated protein
KAM329_15200	COG1175	transmembrane transport
KAM329_15210	COG3833	ABC-type maltose transport systems, permease component
KAM329_15220	COG3842	ATPase activity
KAM329_15240	COG0596	Alpha beta hydrolase
KAM329_15270	COG0425	Belongs to the sulfur carrier protein TusA family
KAM329_15280	COG4783	chaperone-mediated protein folding
KAM329_15300	COG1393	Belongs to the ArsC family
KAM329_15340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM329_15350	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KAM329_15360	COG2431	L-lysine efflux transmembrane transporter activity
KAM329_15380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM329_15400	COG4160	amino acid transport
KAM329_15420	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KAM329_15440	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAM329_15490	COG0628	permease
KAM329_15500	COG2373	Large extracellular alpha-helical protein
KAM329_15510	COG4953	penicillin-binding protein 1C
KAM329_15530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KAM329_15530	COG0301	tRNA thio-modification
KAM329_15650	COG2089	acid synthase
KAM329_15670	COG1083	cytidylyl-transferase
KAM329_15700	COG1028	Short-chain dehydrogenase reductase Sdr
KAM329_15710	COG0318	PFAM AMP-dependent synthetase and ligase
KAM329_15740	COG1215	transferase activity, transferring glycosyl groups
KAM329_15770	COG1216	Glycosyl transferase, family 2
KAM329_15830	COG2226	methyltransferase
KAM329_15840	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KAM329_15850	COG1086	Polysaccharide biosynthesis protein
KAM329_15870	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KAM329_15890	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KAM329_15920	COG0346	lactoylglutathione lyase activity
KAM329_15930	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KAM329_15940	COG4660	Part of a membrane complex involved in electron transport
KAM329_15950	COG4659	FMN binding
KAM329_15960	COG4658	electron transport chain
KAM329_15980	COG4656	Part of a membrane complex involved in electron transport
KAM329_15990	COG2878	Part of a membrane complex involved in electron transport
KAM329_16000	COG4657	Part of a membrane complex involved in electron transport
KAM329_16010	COG0675	Transposase, IS605 OrfB family
KAM329_16030	COG0697	spore germination
KAM329_16060	COG3039	Transposase
KAM329_16070	COG1484	DNA-dependent DNA replication
KAM329_16080	COG4584	PFAM Integrase catalytic
KAM329_16110	COG3335	DDE superfamily endonuclease
KAM329_16160	COG5433	transposase activity
KAM329_16220	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KAM329_16240	COG1288	antiporter activity
KAM329_16250	COG0436	Aminotransferase
KAM329_16270	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KAM329_16280	COG2027	D-alanyl-D-alanine carboxypeptidase
KAM329_16290	COG1061	Type III restriction enzyme res subunit
KAM329_16300	COG1566	PFAM secretion protein HlyD family protein
KAM329_16330	COG0675	Transposase, IS605 OrfB family
KAM329_16340	COG3264	Mechanosensitive ion channel
KAM329_16340	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KAM329_16350	COG1966	Carbon starvation protein
KAM329_16360	COG3279	Response regulator of the LytR AlgR family
KAM329_16370	COG3275	phosphorelay sensor kinase activity
KAM329_16390	COG1012	belongs to the aldehyde dehydrogenase family
KAM329_16390	COG1454	alcohol dehydrogenase
KAM329_16400	COG2095	MarC family integral membrane protein
KAM329_16420	COG0601	transmembrane transport
KAM329_16430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAM329_16440	COG0444	Belongs to the ABC transporter superfamily
KAM329_16460	COG0861	Integral membrane protein TerC family
KAM329_16470	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KAM329_16490	COG1301	dicarboxylic acid transport
KAM329_16520	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KAM329_16550	COG0537	adenosine 5'-monophosphoramidase activity
KAM329_16620	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAM329_16630	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAM329_16660	COG2354	Protein conserved in bacteria
KAM329_16670	COG1164	Oligoendopeptidase f
KAM329_16680	COG1164	Oligoendopeptidase f
KAM329_16690	COG3150	esterase
KAM329_16700	COG1252	NADH dehydrogenase
KAM329_16710	COG0393	Putative heavy-metal-binding
KAM329_16720	COG1368	sulfuric ester hydrolase activity
KAM329_16740	COG0527	aspartate kinase activity
KAM329_16760	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KAM329_16760	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KAM329_16770	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KAM329_16820	COG0583	DNA-binding transcription factor activity
KAM329_16830	COG1620	l-lactate permease
KAM329_16840	COG0247	lactate metabolic process
KAM329_16850	COG1139	Iron-sulfur cluster binding protein
KAM329_16890	COG0577	efflux transmembrane transporter activity
KAM329_16900	COG1136	(ABC) transporter
KAM329_16940	COG2814	Major facilitator Superfamily
KAM329_16990	COG0672	)-iron permease
KAM329_17060	COG2308	Evidence 4 Homologs of previously reported genes of
KAM329_17080	COG0300	oxidoreductase activity
KAM329_17110	COG0659	secondary active sulfate transmembrane transporter activity
KAM329_17140	COG2003	Belongs to the UPF0758 family
KAM329_17190	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KAM329_17200	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KAM329_17220	COG0326	Molecular chaperone. Has ATPase activity
KAM329_17230	COG0563	adenylate kinase activity
KAM329_17240	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KAM329_17250	COG3788	relative of glutathione S-transferase, MAPEG superfamily
KAM329_17260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM329_17270	COG0840	transmembrane signaling receptor activity
KAM329_17290	COG0675	Transposase, IS605 OrfB family
KAM329_17330	COG5001	Diguanylate cyclase
KAM329_17330	COG3300	MHYT domain
KAM329_17380	COG1021	2,3-dihydroxybenzoate-AMP ligase
KAM329_17390	COG1535	isochorismatase
KAM329_17390	COG3433	isochorismatase activity
KAM329_17400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KAM329_17410	COG1028	Short-chain dehydrogenase reductase Sdr
KAM329_17440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KAM329_17480	COG1120	ATPase activity
KAM329_17490	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAM329_17500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAM329_17510	COG4771	TonB-dependent receptor
KAM329_17590	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KAM329_17600	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KAM329_17610	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAM329_17620	COG0861	Integral membrane protein TerC family
KAM329_17650	COG1022	Amp-dependent synthetase and ligase
KAM329_17660	COG0295	cytidine deaminase activity
KAM329_17670	COG1346	cytolysis
KAM329_17680	COG1380	Effector of murein hydrolase LrgA
KAM329_17690	COG3345	alpha-galactosidase
KAM329_17710	COG2925	Exonuclease
KAM329_17730	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KAM329_17750	COG0392	lysyltransferase activity
KAM329_17750	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KAM329_17780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KAM329_17790	COG0436	Aminotransferase
KAM329_17800	COG0583	DNA-binding transcription factor activity
KAM329_17810	COG2160	L-arabinose isomerase activity
KAM329_17830	COG1069	ribulokinase activity
KAM329_17840	COG1879	ABC-type sugar transport system periplasmic component
KAM329_17850	COG1129	ABC transporter
KAM329_17860	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAM329_17880	COG0254	rRNA binding
KAM329_17910	COG1451	nucleotide metabolic process
KAM329_17950	COG3069	C4-dicarboxylate transmembrane transporter activity
KAM329_17970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAM329_17970	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KAM329_17980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KAM329_18020	COG2009	succinate dehydrogenase
KAM329_18030	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KAM329_18060	COG0567	Dehydrogenase, E1 component
KAM329_18070	COG0508	dehydrogenase complex catalyzes the overall conversion of
KAM329_18080	COG0045	succinate-CoA ligase (ADP-forming) activity
KAM329_18090	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KAM329_18100	COG2801	Transposase and inactivated derivatives
KAM329_18140	COG2983	Belongs to the UPF0260 family
KAM329_18150	COG1882	Formate acetyltransferase
KAM329_18160	COG2116	formate transmembrane transporter activity
KAM329_18170	COG1944	ATP diphosphatase activity
KAM329_18190	COG2076	Multidrug Resistance protein
KAM329_18200	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KAM329_18210	COG1278	Cold shock
KAM329_18220	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KAM329_18230	COG0542	response to heat
KAM329_18240	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KAM329_18250	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KAM329_18260	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KAM329_18270	COG3134	Outer membrane lipoprotein
KAM329_18280	COG3706	GGDEF domain
KAM329_18290	COG0492	ferredoxin-NADP+ reductase activity
KAM329_18300	COG0686	Belongs to the AlaDH PNT family
KAM329_18320	COG0531	amino acid
KAM329_18320	COG1674	ftsk spoiiie
KAM329_18330	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KAM329_18340	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KAM329_18350	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KAM329_18360	COG1286	toxin biosynthetic process
KAM329_18370	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KAM329_18380	COG2723	6-phospho-beta-galactosidase activity
KAM329_18390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM329_18390	COG1263	PTS System
KAM329_18400	COG1609	Transcriptional regulator
KAM329_18420	COG4172	Belongs to the ABC transporter superfamily
KAM329_18440	COG4171	peptide transport system, permease
KAM329_18470	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KAM329_18480	COG1842	Phage shock protein A
KAM329_18510	COG3106	COG3106 Predicted ATPase
KAM329_18520	COG3768	UPF0283 membrane protein
KAM329_18540	COG2154	pterin-4-alpha-carbinolamine dehydratase
KAM329_18590	COG2885	chlorophyll binding
KAM329_18600	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KAM329_18620	COG1570	exodeoxyribonuclease VII activity
KAM329_18720	COG3415	Transposase
KAM329_18720	COG2801	Transposase and inactivated derivatives
KAM329_18750	COG3220	belongs to the UPF0276 family
KAM329_18790	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KAM329_18800	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
KAM329_18820	COG1595	DNA-templated transcription, initiation
KAM329_18840	COG3039	Transposase
KAM329_18850	COG1874	Beta-galactosidase
KAM329_18850	COG0366	Alpha amylase catalytic
KAM329_18880	COG0516	GMP reductase activity
KAM329_18880	COG0517	IMP dehydrogenase activity
KAM329_18890	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KAM329_18890	COG0519	Catalyzes the synthesis of GMP from XMP
KAM329_18940	COG1846	Transcriptional regulator
KAM329_18960	COG0500	methyltransferase
KAM329_18980	COG2062	phosphohistidine phosphatase, SixA
KAM329_19000	COG0697	spore germination
KAM329_19020	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
KAM329_19040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KAM329_19060	COG4591	ABC-type transport system involved in lipoprotein release permease component
KAM329_19070	COG1136	(ABC) transporter
KAM329_19080	COG4591	ABC-type transport system involved in lipoprotein release permease component
KAM329_19090	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KAM329_19120	COG0544	peptidyl-prolyl cis-trans isomerase activity
KAM329_19130	COG0740	serine-type endopeptidase activity
KAM329_19140	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KAM329_19150	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KAM329_19160	COG0776	regulation of translation
KAM329_19170	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KAM329_19180	COG0488	(ABC) transporter
KAM329_19190	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KAM329_19200	COG3162	membrane
KAM329_19230	COG1024	Enoyl-CoA hydratase
KAM329_19240	COG1115	amino acid carrier protein
KAM329_19260	COG3228	Belongs to the MtfA family
KAM329_19270	COG1584	GPR1 FUN34 yaaH family protein
KAM329_19320	COG1024	Enoyl-CoA hydratase
KAM329_19330	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KAM329_19340	COG1960	acyl-CoA dehydrogenase activity
KAM329_19360	COG1960	acyl-CoA dehydrogenase activity
KAM329_19370	COG1024	Enoyl-CoA hydratase
KAM329_19380	COG1024	Enoyl-CoA hydratase
KAM329_19400	COG1028	Short-chain dehydrogenase reductase Sdr
KAM329_19420	COG0730	response to heat
KAM329_19440	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAM329_19450	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAM329_19460	COG1129	ABC transporter
KAM329_19470	COG3385	transposase activity
KAM329_19480	COG1879	ABC-type sugar transport system periplasmic component
KAM329_19490	COG0583	DNA-binding transcription factor activity
KAM329_19520	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KAM329_19530	COG0243	molybdopterin cofactor binding
KAM329_19560	COG0583	DNA-binding transcription factor activity
KAM329_19570	COG2723	6-phospho-beta-galactosidase activity
KAM329_19590	COG0583	DNA-binding transcription factor activity
KAM329_19620	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KAM329_19630	COG0673	inositol 2-dehydrogenase activity
KAM329_19640	COG0583	DNA-binding transcription factor activity
KAM329_19660	COG1560	Kdo2-lipid A biosynthetic process
KAM329_19670	COG1560	Kdo2-lipid A biosynthetic process
KAM329_19700	COG0417	DNA replication proofreading
KAM329_19940	COG0625	glutathione transferase activity
KAM329_19950	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KAM329_19970	COG0583	DNA-binding transcription factor activity
KAM329_20000	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KAM329_20030	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KAM329_20070	COG1846	Transcriptional regulator
KAM329_20080	COG0583	DNA-binding transcription factor activity
KAM329_20100	COG2948	multi-organism process
KAM329_20300	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM329_20320	COG3385	transposase activity
KAM329_20340	COG3335	DDE superfamily endonuclease
KAM329_20370	COG5433	transposase activity
KAM329_20380	COG5433	transposase activity
KAM329_20390	COG3284	Transcriptional regulator
KAM329_20420	COG1461	Dihydroxyacetone kinase
KAM329_20430	COG2376	Dihydroxyacetone kinase
KAM329_20440	COG2252	PERMEase
KAM329_20500	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KAM329_20530	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KAM329_20560	COG5433	transposase activity
KAM329_20610	COG0534	Mate efflux family protein
KAM329_20630	COG0307	riboflavin synthase, alpha
KAM329_20660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAM329_20670	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KAM329_20680	COG0697	spore germination
KAM329_20690	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KAM329_20750	COG0675	Transposase, IS605 OrfB family
KAM329_20760	COG2996	Protein conserved in bacteria
KAM329_20790	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KAM329_20800	COG3099	Belongs to the UPF0263 family
KAM329_20810	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KAM329_20820	COG2894	cell division
KAM329_20830	COG0850	regulation of cytokinetic process
KAM329_20840	COG3100	YcgL domain-containing protein
KAM329_20850	COG2951	lytic endotransglycosylase activity
KAM329_20860	COG1760	l-serine dehydratase
KAM329_20870	COG1760	l-serine dehydratase
KAM329_20880	COG3123	guanosine phosphorylase activity
KAM329_20890	COG1301	dicarboxylic acid transport
KAM329_20920	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KAM329_20930	COG2067	long-chain fatty acid transport protein
KAM329_20940	COG2067	long-chain fatty acid transport protein
KAM329_20960	COG1595	DNA-templated transcription, initiation
KAM329_21010	COG0714	Associated with various cellular activities
KAM329_21020	COG0183	Belongs to the thiolase family
KAM329_21030	COG1024	Enoyl-CoA hydratase
KAM329_21030	COG1250	3-hydroxyacyl-CoA dehydrogenase
KAM329_21050	COG4681	YaeQ
KAM329_21090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAM329_21120	COG3134	Outer membrane lipoprotein
KAM329_21140	COG0675	Transposase, IS605 OrfB family
KAM329_21150	COG0318	PFAM AMP-dependent synthetase and ligase
KAM329_21160	COG2378	regulation of single-species biofilm formation
KAM329_21180	COG0140	phosphoribosyl-ATP diphosphatase activity
KAM329_21180	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KAM329_21190	COG0107	imidazoleglycerol-phosphate synthase activity
KAM329_21200	COG0784	Response regulator, receiver
KAM329_21200	COG2198	Histidine kinase
KAM329_21200	COG2205	protein histidine kinase activity
KAM329_21210	COG2199	diguanylate cyclase activity
KAM329_21220	COG3437	response regulator, receiver
KAM329_21230	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KAM329_21240	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KAM329_21250	COG0131	Imidazoleglycerol-phosphate dehydratase
KAM329_21250	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KAM329_21260	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KAM329_21270	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KAM329_21280	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KAM329_21300	COG1199	ATP-dependent helicase activity
KAM329_21310	COG3385	transposase activity
KAM329_21320	COG1214	PFAM Peptidase M22, glycoprotease
KAM329_21340	COG0596	Alpha beta hydrolase
KAM329_21350	COG0318	PFAM AMP-dependent synthetase and ligase
KAM329_21380	COG0697	spore germination
KAM329_21400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KAM329_21410	COG2832	Protein of unknown function (DUF454)
KAM329_21420	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KAM329_21440	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KAM329_21450	COG0583	DNA-binding transcription factor activity
KAM329_21470	COG3314	Sporulation integral membrane protein YlbJ
KAM329_21560	COG2197	response regulator
KAM329_21570	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KAM329_21570	COG0517	IMP dehydrogenase activity
KAM329_21570	COG0617	tRNA 3'-terminal CCA addition
KAM329_21580	COG1643	Atp-dependent helicase
KAM329_21600	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KAM329_21630	COG0675	Transposase, IS605 OrfB family
KAM329_21640	COG0784	Response regulator, receiver
KAM329_21640	COG5002	protein histidine kinase activity
KAM329_21640	COG2205	protein histidine kinase activity
KAM329_21690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KAM329_21700	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
KAM329_21710	COG0709	Synthesizes selenophosphate from selenide and ATP
KAM329_21740	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KAM329_21750	COG0840	transmembrane signaling receptor activity
KAM329_21760	COG1254	Belongs to the acylphosphatase family
KAM329_21780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM329_21780	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM329_21790	COG0489	protein tyrosine kinase activity
KAM329_21800	COG0572	uridine kinase
KAM329_21810	COG0717	Belongs to the dCTP deaminase family
KAM329_21820	COG0306	phosphate transporter
KAM329_21830	COG1530	ribonuclease E activity
KAM329_21840	COG0564	pseudouridine synthase activity
KAM329_21870	COG1399	metal-binding, possibly nucleic acid-binding protein
KAM329_21880	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KAM329_21890	COG0416	fatty acid biosynthetic process
KAM329_21900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KAM329_21920	COG1028	Short-chain dehydrogenase reductase Sdr
KAM329_21930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KAM329_21940	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KAM329_21950	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KAM329_21960	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KAM329_21970	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KAM329_21980	COG0470	DNA polymerase III
KAM329_21990	COG0084	hydrolase, TatD family'
KAM329_22020	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KAM329_22020	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
KAM329_22030	COG3008	intermembrane lipid transfer
KAM329_22040	COG2995	paraquat-inducible protein a
KAM329_22060	COG3141	response to X-ray
KAM329_22110	COG3039	Transposase
KAM329_22210	COG5642	Protein of unknown function (DUF2384)
KAM329_22230	COG3328	transposase activity
KAM329_22240	COG3385	transposase activity
KAM329_22300	COG3039	Transposase
KAM329_22320	COG5499	transcription regulator containing HTH domain
KAM329_22330	COG1067	ATP-dependent peptidase activity
KAM329_22340	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KAM329_22370	COG0488	(ABC) transporter
KAM329_22390	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KAM329_22390	COG0116	Belongs to the methyltransferase superfamily
KAM329_22410	COG0167	dihydroorotate dehydrogenase activity
KAM329_22420	COG2902	Dehydrogenase
KAM329_22440	COG0308	aminopeptidase N
KAM329_22460	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
KAM329_22470	COG1956	GAF domain-containing protein
KAM329_22490	COG3278	Belongs to the heme-copper respiratory oxidase family
KAM329_22520	COG2010	Cytochrome c
KAM329_22540	COG2217	Heavy metal translocating P-type atpase
KAM329_22570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KAM329_22580	COG0589	response to stress
KAM329_22590	COG0037	tRNA processing
KAM329_22620	COG0625	glutathione transferase activity
KAM329_22630	COG1869	D-ribose catabolic process
KAM329_22640	COG1129	ABC transporter
KAM329_22650	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAM329_22660	COG1879	ABC-type sugar transport system periplasmic component
KAM329_22670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM329_22680	COG1609	Transcriptional regulator
KAM329_22710	COG5001	Diguanylate cyclase
KAM329_22710	COG3300	MHYT domain
KAM329_22780	COG0776	regulation of translation
KAM329_22790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM329_22790	COG0072	phenylalanine-tRNA ligase activity
KAM329_22800	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KAM329_22810	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KAM329_22820	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KAM329_22830	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KAM329_22840	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KAM329_22940	COG0675	Transposase, IS605 OrfB family
KAM329_22980	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KAM329_23000	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KAM329_23010	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KAM329_23020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KAM329_23030	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
KAM329_23040	COG3313	Fe-S protein
KAM329_23050	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KAM329_23050	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KAM329_23050	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KAM329_23060	COG1105	Belongs to the carbohydrate kinase PfkB family
KAM329_23070	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM329_23070	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM329_23080	COG1609	Transcriptional regulator
KAM329_23090	COG0814	amino acid
KAM329_23120	COG0513	Belongs to the DEAD box helicase family
KAM329_23140	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KAM329_23150	COG2890	protein-(glutamine-N5) methyltransferase activity
KAM329_23160	COG2840	Smr protein MutS2
KAM329_23230	COG2824	Alkylphosphonate utilization operon protein PhnA
KAM329_23260	COG1280	lysine exporter protein (LysE YggA)
KAM329_23290	COG0675	Transposase, IS605 OrfB family
KAM329_23370	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KAM329_23380	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
KAM329_23400	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KAM329_23410	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KAM329_23430	COG0205	6-phosphofructokinase activity
KAM329_23440	COG1473	amidohydrolase
KAM329_23450	COG1011	Hydrolase
KAM329_23460	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KAM329_23480	COG3593	DNA synthesis involved in DNA repair
KAM329_23510	COG0583	DNA-binding transcription factor activity
KAM329_23520	COG0730	response to heat
KAM329_23530	COG3148	PFAM DTW domain containing protein
KAM329_23540	COG1181	Belongs to the D-alanine--D-alanine ligase family
KAM329_23560	COG0386	Belongs to the glutathione peroxidase family
KAM329_23570	COG0513	Belongs to the DEAD box helicase family
KAM329_23600	COG1742	UPF0060 membrane protein
KAM329_23650	COG2329	Antibiotic biosynthesis monooxygenase
KAM329_23660	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KAM329_23700	COG3243	poly(R)-hydroxyalkanoic acid synthase
KAM329_23720	COG2501	S4 domain
KAM329_23750	COG1132	(ABC) transporter
KAM329_23760	COG1132	(ABC) transporter
KAM329_23780	COG3118	belongs to the thioredoxin family
KAM329_23790	COG3118	belongs to the thioredoxin family
KAM329_23800	COG0471	metal ion transport
KAM329_23820	COG0058	SHG alpha-glucan phosphorylase activity
KAM329_23880	COG0814	amino acid
KAM329_23890	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KAM329_23900	COG0514	ATP-dependent DNA helicase (RecQ)
KAM329_23910	COG2766	serine protein kinase
KAM329_23920	COG2718	Belongs to the UPF0229 family
KAM329_23930	COG2719	SpoVR family
KAM329_23940	COG2186	Transcriptional regulator
KAM329_23950	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KAM329_23960	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KAM329_23970	COG0586	Pfam SNARE associated Golgi protein
KAM329_23990	COG0556	nucleotide-excision repair
KAM329_24000	COG2985	domain, Protein
KAM329_24000	COG0569	domain protein
KAM329_24030	COG1196	nuclear chromosome segregation
KAM329_24030	COG0741	lytic transglycosylase activity
KAM329_24030	COG0739	heme binding
KAM329_24040	COG0675	Transposase, IS605 OrfB family
KAM329_24090	COG4565	transcriptional regulatory protein
KAM329_24100	COG3290	protein histidine kinase activity
KAM329_24110	COG1846	Transcriptional regulator
KAM329_24110	COG1940	carbohydrate kinase activity
KAM329_24120	COG0840	transmembrane signaling receptor activity
KAM329_24140	COG3012	SEC-C Motif Domain Protein
KAM329_24150	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KAM329_24160	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KAM329_24170	COG0247	lactate metabolic process
KAM329_24190	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
KAM329_24200	COG0437	4 iron, 4 sulfur cluster binding
KAM329_24210	COG3301	Polysulphide reductase, NrfD
KAM329_24220	COG1138	Cytochrome C-type biogenesis protein
KAM329_24230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KAM329_24240	COG4235	cytochrome complex assembly
KAM329_24240	COG3088	subunit of a heme lyase
KAM329_24260	COG3046	protein related to deoxyribodipyrimidine photolyase
KAM329_24270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAM329_24300	COG0617	tRNA 3'-terminal CCA addition
KAM329_24300	COG0517	IMP dehydrogenase activity
KAM329_24300	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KAM329_24320	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KAM329_24330	COG0583	DNA-binding transcription factor activity
KAM329_24350	COG4774	siderophore transport
KAM329_24360	COG2203	Gaf domain
KAM329_24360	COG2199	diguanylate cyclase activity
KAM329_24370	COG2200	EAL domain
KAM329_24380	COG4977	sequence-specific DNA binding
KAM329_24380	COG1917	Cupin 2, conserved barrel domain protein
KAM329_24390	COG0583	DNA-binding transcription factor activity
KAM329_24400	COG2910	NAD(P)H-binding
KAM329_24430	COG0626	cystathionine gamma-synthase activity
KAM329_24440	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KAM329_24570	COG1484	DNA-dependent DNA replication
KAM329_24590	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KAM329_24600	COG0830	nickel cation binding
KAM329_24620	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
KAM329_24630	COG0804	urea catabolic process
KAM329_24640	COG0832	Belongs to the urease beta subunit family
KAM329_24650	COG0831	urea catabolic process
KAM329_24660	COG0829	nickel cation binding
KAM329_24680	COG0411	ABC transporter
KAM329_24750	COG0784	Response regulator, receiver
KAM329_24750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM329_24750	COG2198	Histidine kinase
KAM329_24750	COG2205	protein histidine kinase activity
KAM329_24760	COG0745	RESPONSE REGULATOR receiver
KAM329_24790	COG3039	Transposase
KAM329_24820	COG0675	Transposase, IS605 OrfB family
KAM329_24970	COG3550	peptidyl-serine autophosphorylation
KAM329_25020	COG3039	Transposase
KAM329_25130	COG1435	thymidine kinase activity
KAM329_25140	COG1757	Na H antiporter
KAM329_25150	COG2916	Histone family protein nucleoid-structuring protein H-NS
KAM329_25160	COG2096	Adenosyltransferase
KAM329_25170	COG3530	Putative quorum-sensing-regulated virulence factor
KAM329_25180	COG0602	queuosine metabolic process
KAM329_25190	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KAM329_25230	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KAM329_25250	COG0776	regulation of translation
KAM329_25260	COG0539	negative regulation of cytoplasmic translation
KAM329_25270	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KAM329_25280	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KAM329_25340	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KAM329_25350	COG5001	Diguanylate cyclase
KAM329_25350	COG3300	MHYT domain
KAM329_25370	COG0583	DNA-binding transcription factor activity
KAM329_25390	COG0745	RESPONSE REGULATOR receiver
KAM329_25440	COG4989	oxidoreductase activity
KAM329_25450	COG0724	RNA recognition motif
KAM329_25470	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
KAM329_25490	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KAM329_25510	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KAM329_25520	COG1360	Flagellar Motor Protein
KAM329_25530	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM329_25540	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM329_25550	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM329_25550	COG0649	NAD binding
KAM329_25580	COG1034	ATP synthesis coupled electron transport
KAM329_25590	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KAM329_25600	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM329_25610	COG0839	Belongs to the complex I subunit 6 family
KAM329_25620	COG0713	ATP synthesis coupled electron transport
KAM329_25640	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM329_25650	COG1007	ATP synthesis coupled electron transport
KAM329_25660	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KAM329_25660	COG0047	phosphoribosylformylglycinamidine synthase activity
KAM329_25670	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KAM329_25690	COG1645	bacterial-type flagellum-dependent swarming motility
KAM329_25700	COG1160	GTP binding
KAM329_25710	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAM329_25720	COG2976	Protein conserved in bacteria
KAM329_25730	COG0124	histidyl-tRNA synthetase
KAM329_25750	COG1426	Protein conserved in bacteria
KAM329_25770	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KAM329_25780	COG0105	UTP biosynthetic process
KAM329_25810	COG0633	Ferredoxin
KAM329_25820	COG0443	Heat shock 70 kDa protein
KAM329_25830	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KAM329_25850	COG0822	iron-sulfur transferase activity
KAM329_25860	COG1104	cysteine desulfurase activity
KAM329_25890	COG3154	lipid carrier protein
KAM329_25900	COG0826	peptidase U32
KAM329_25910	COG0826	peptidase U32
KAM329_25950	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAM329_25960	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAM329_25970	COG1862	Preprotein translocase
KAM329_25980	COG0343	queuine tRNA-ribosyltransferase activity
KAM329_25990	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KAM329_26000	COG0517	IMP dehydrogenase activity
KAM329_26010	COG0450	alkyl hydroperoxide reductase
KAM329_26020	COG3634	alkyl hydroperoxide reductase activity
KAM329_26030	COG0477	Major facilitator Superfamily
KAM329_26130	COG3385	transposase activity
KAM329_26180	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KAM329_26190	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KAM329_26230	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KAM329_26230	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KAM329_26240	COG0509	glycine decarboxylation via glycine cleavage system
KAM329_26250	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KAM329_26260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KAM329_26270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KAM329_26300	COG2814	Major facilitator Superfamily
KAM329_26320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAM329_26330	COG0601	transmembrane transport
KAM329_26350	COG0625	glutathione transferase activity
KAM329_26360	COG0625	glutathione transferase activity
KAM329_26380	COG0483	inositol monophosphate 1-phosphatase activity
KAM329_26420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KAM329_26430	COG2056	Na+-H+ antiporter family
KAM329_26440	COG2814	Major facilitator Superfamily
KAM329_26450	COG0583	DNA-binding transcription factor activity
KAM329_26460	COG5001	Diguanylate cyclase
KAM329_26490	COG2050	protein possibly involved in aromatic compounds catabolism
KAM329_26510	COG0277	FAD linked oxidase domain protein
KAM329_26510	COG0247	lactate metabolic process
KAM329_26540	COG3039	Transposase
KAM329_26550	COG1253	flavin adenine dinucleotide binding
KAM329_26560	COG1902	pentaerythritol trinitrate reductase activity
KAM329_26580	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KAM329_26590	COG0647	UMP catabolic process
KAM329_26610	COG0367	asparagine synthase
KAM329_26640	COG0625	glutathione transferase activity
KAM329_26660	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KAM329_26690	COG0564	pseudouridine synthase activity
KAM329_26700	COG5001	Diguanylate cyclase
KAM329_26720	COG0840	transmembrane signaling receptor activity
KAM329_26730	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KAM329_26810	COG0670	Belongs to the BI1 family
KAM329_26820	COG1289	transmembrane transporter activity
KAM329_26830	COG2920	part of a sulfur-relay system
KAM329_26840	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
KAM329_26850	COG0285	dihydrofolate synthase activity
KAM329_26860	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KAM329_26870	COG0101	tRNA pseudouridine synthase activity
KAM329_26890	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KAM329_26900	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KAM329_26920	COG1464	Belongs to the NlpA lipoprotein family
KAM329_26970	COG1119	ATPase activity
KAM329_26980	COG0574	Belongs to the PEP-utilizing enzyme family
KAM329_26980	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KAM329_26990	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KAM329_27010	COG1113	amino acid transport
KAM329_27110	COG5433	transposase activity
KAM329_27170	COG1242	4 iron, 4 sulfur cluster binding
KAM329_27180	COG0067	glutamate synthase
KAM329_27180	COG0070	glutamate synthase
KAM329_27180	COG0069	glutamate synthase activity
KAM329_27190	COG0493	'glutamate synthase
KAM329_27200	COG1126	abc transporter atp-binding protein
KAM329_27210	COG0765	amino acid transport
KAM329_27220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM329_27270	COG4104	PAAR repeat-containing protein
KAM329_27290	COG0513	Belongs to the DEAD box helicase family
KAM329_27330	COG3039	Transposase
KAM329_27360	COG3706	GGDEF domain
KAM329_27370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KAM329_27390	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KAM329_27400	COG0505	Belongs to the CarA family
KAM329_27410	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KAM329_27430	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KAM329_27440	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KAM329_27450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KAM329_27460	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KAM329_27470	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAM329_27480	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
KAM329_27490	COG4139	cobalamin transport
KAM329_27540	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KAM329_27560	COG0023	Translation Initiation Factor
KAM329_27570	COG2119	membrane
KAM329_27640	COG2199	diguanylate cyclase activity
KAM329_27640	COG2203	Gaf domain
KAM329_27650	COG3039	Transposase
KAM329_27680	COG0215	cysteine-tRNA ligase activity
KAM329_27690	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KAM329_27710	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAM329_27720	COG2261	transglycosylase associated protein
KAM329_27730	COG1309	transcriptional regulator
KAM329_27740	COG0604	alcohol dehydrogenase
KAM329_27770	COG0583	DNA-binding transcription factor activity
KAM329_27790	COG0322	excinuclease ABC activity
KAM329_27800	COG2197	response regulator
KAM329_27810	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KAM329_27820	COG2835	tetraacyldisaccharide 4'-kinase activity
KAM329_27830	COG1663	tetraacyldisaccharide 4'-kinase activity
KAM329_27840	COG1132	(ABC) transporter
KAM329_27850	COG2333	competence protein COMEC
KAM329_27850	COG0658	competence protein
KAM329_27880	COG0433	COG0433 Predicted ATPase
KAM329_27890	COG1448	Aminotransferase
KAM329_27920	COG1199	ATP-dependent helicase activity
KAM329_27940	COG0123	including yeast histone deacetylase and acetoin utilization protein
KAM329_27950	COG0477	Major facilitator Superfamily
KAM329_27960	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KAM329_27970	COG1785	Belongs to the alkaline phosphatase family
KAM329_28010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KAM329_28020	COG3706	GGDEF domain
KAM329_28040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM329_28050	COG0765	amino acid transport
KAM329_28060	COG1126	abc transporter atp-binding protein
KAM329_28090	COG0531	amino acid
KAM329_28120	COG1253	flavin adenine dinucleotide binding
KAM329_28130	COG0704	Plays a role in the regulation of phosphate uptake
KAM329_28140	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KAM329_28150	COG0581	inorganic phosphate transmembrane transporter activity
KAM329_28160	COG0573	inorganic phosphate transmembrane transporter activity
KAM329_28170	COG0590	tRNA wobble adenosine to inosine editing
KAM329_28190	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KAM329_28210	COG0675	Transposase, IS605 OrfB family
KAM329_28250	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KAM329_28260	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KAM329_28270	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KAM329_28280	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KAM329_28330	COG2716	regulation of RNA biosynthetic process
KAM329_28340	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KAM329_28360	COG2239	Acts as a magnesium transporter
KAM329_28390	COG1705	Flagellar rod assembly protein muramidase FlgJ
KAM329_28390	COG3951	Flagellar rod assembly protein muramidase FlgJ
KAM329_28400	COG1706	bacterial-type flagellum-dependent cell motility
KAM329_28410	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KAM329_28440	COG1749	Flagellar hook protein flgE
KAM329_28470	COG1815	bacterial-type flagellum-dependent cell motility
KAM329_28480	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KAM329_28490	COG0784	Response regulator, receiver
KAM329_28490	COG0835	chemotaxis
KAM329_28500	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
KAM329_28530	COG0622	Phosphoesterase
KAM329_28540	COG0675	Transposase, IS605 OrfB family
KAM329_28560	COG4166	transmembrane transport
KAM329_28590	COG0675	Transposase, IS605 OrfB family
KAM329_28610	COG0697	spore germination
KAM329_28680	COG1278	Cold shock
KAM329_28710	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KAM329_28760	COG3132	Protein of unknown function, DUF480
KAM329_28780	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAM329_28820	COG0489	protein tyrosine kinase activity
KAM329_28820	COG3206	protein involved in exopolysaccharide biosynthesis
KAM329_28830	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KAM329_29000	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KAM329_29020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KAM329_29130	COG1091	dTDP-4-dehydrorhamnose reductase activity
KAM329_29150	COG3039	Transposase
KAM329_29200	COG1737	Transcriptional regulator
KAM329_29210	COG0469	pyruvate kinase activity
KAM329_29230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM329_29240	COG1960	acyl-CoA dehydrogenase activity
KAM329_29260	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KAM329_29300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM329_29310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM329_29320	COG1309	transcriptional regulator
KAM329_29350	COG1946	Acyl-CoA thioesterase
KAM329_29380	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KAM329_29400	COG0009	L-threonylcarbamoyladenylate synthase
KAM329_29410	COG0613	PHP domain protein
KAM329_29420	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KAM329_29430	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KAM329_29430	COG0512	Glutamine amidotransferase of anthranilate synthase
KAM329_29440	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KAM329_29450	COG0135	phosphoribosylanthranilate isomerase activity
KAM329_29450	COG0134	indole-3-glycerol-phosphate synthase activity
KAM329_29460	COG0133	tryptophan synthase activity
KAM329_29470	COG0159	tryptophan synthase activity
KAM329_29490	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KAM329_29510	COG1396	sequence-specific DNA binding
KAM329_29520	COG3550	peptidyl-serine autophosphorylation
KAM329_29560	COG0583	DNA-binding transcription factor activity
KAM329_29580	COG5507	3-demethylubiquinone-9 3-methyltransferase
KAM329_29590	COG2814	Major facilitator Superfamily
KAM329_29600	COG0109	protoheme IX farnesyltransferase activity
KAM329_29610	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KAM329_29620	COG1845	cytochrome c oxidase, subunit III
KAM329_29630	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KAM329_29640	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KAM329_29650	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KAM329_29660	COG0583	DNA-binding transcription factor activity
KAM329_29700	COG1846	Transcriptional regulator
KAM329_29730	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
KAM329_29770	COG0745	RESPONSE REGULATOR receiver
KAM329_29790	COG0708	Exodeoxyribonuclease III
KAM329_29810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM329_29820	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM329_29850	COG0095	Lipoate-protein ligase
KAM329_29910	COG0640	Transcriptional regulator
KAM329_29930	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAM329_29950	COG1285	pathogenesis
KAM329_30020	COG0484	heat shock protein binding
KAM329_30030	COG0443	Heat shock 70 kDa protein
KAM329_30040	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KAM329_30060	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KAM329_30070	COG3706	GGDEF domain
KAM329_30080	COG0497	DNA recombination
KAM329_30100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM329_30110	COG1136	(ABC) transporter
KAM329_30110	COG0577	efflux transmembrane transporter activity
KAM329_30120	COG1538	Outer membrane efflux protein
KAM329_30130	COG2375	cellular response to nickel ion
KAM329_30140	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAM329_30150	COG2916	Histone family protein nucleoid-structuring protein H-NS
KAM329_30160	COG0583	DNA-binding transcription factor activity
KAM329_30170	COG3048	D-serine ammonia-lyase activity
KAM329_30190	COG0538	isocitrate dehydrogenase activity
KAM329_30270	COG0456	acetyltransferase
KAM329_30280	COG1187	pseudouridine synthase activity
KAM329_30300	COG0482	sulfurtransferase activity
KAM329_30310	COG2915	High frequency lysogenization protein hflD homolog
KAM329_30320	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KAM329_30330	COG2850	peptidyl-arginine hydroxylation
KAM329_30350	COG3264	Mechanosensitive ion channel
KAM329_30350	COG1196	nuclear chromosome segregation
KAM329_30410	COG0281	malic enzyme
KAM329_30420	COG0746	molybdenum cofactor guanylyltransferase activity
KAM329_30430	COG1763	Mo-molybdopterin cofactor biosynthetic process
KAM329_30440	COG1289	transmembrane transporter activity
KAM329_30450	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KAM329_30510	COG3220	belongs to the UPF0276 family
KAM329_30530	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KAM329_30620	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KAM329_30630	COG0083	homoserine kinase activity
KAM329_30650	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
KAM329_30660	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
KAM329_30700	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KAM329_30720	COG0745	RESPONSE REGULATOR receiver
KAM329_30730	COG4988	ABC transporter
KAM329_30740	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KAM329_30790	COG1720	tRNA m6t6A37 methyltransferase activity
KAM329_30820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KAM329_30830	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KAM329_30840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM329_30860	COG2190	(PTS) system
KAM329_30870	COG3038	cytochrome b561
KAM329_30890	COG0420	3'-5' exonuclease activity
KAM329_30910	COG1247	-acetyltransferase
KAM329_30920	COG2974	May be involved in recombination
KAM329_30940	COG0405	Gamma-glutamyltransferase
KAM329_30950	COG4651	solute:proton antiporter activity
KAM329_30950	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KAM329_31050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAM329_31060	COG1917	Cupin 2, conserved barrel domain protein
KAM329_31060	COG1396	sequence-specific DNA binding
KAM329_31070	COG1012	belongs to the aldehyde dehydrogenase family
KAM329_31100	COG0531	amino acid
KAM329_31110	COG0531	amino acid
KAM329_31130	COG1283	sodium-dependent phosphate transmembrane transporter activity
KAM329_31150	COG3384	dioxygenase
KAM329_31160	COG2205	protein histidine kinase activity
KAM329_31160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM329_31170	COG0784	Response regulator, receiver
KAM329_31170	COG2205	protein histidine kinase activity
KAM329_31170	COG2198	Histidine kinase
KAM329_31170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM329_31200	COG2205	protein histidine kinase activity
KAM329_31200	COG0784	Response regulator, receiver
KAM329_31210	COG0582	viral genome integration into host DNA
KAM329_31280	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM329_31360	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM329_31370	COG3041	Addiction module toxin RelE StbE family
KAM329_31470	COG2176	DNA-directed DNA polymerase activity
KAM329_31470	COG5002	protein histidine kinase activity
KAM329_31550	COG1192	Involved in chromosome partitioning
KAM329_31620	COG1376	ErfK ybiS ycfS ynhG family protein
KAM329_31620	COG1388	LysM domain
KAM329_31650	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
KAM329_31660	COG0791	NLP P60 protein
KAM329_31680	COG3118	belongs to the thioredoxin family
KAM329_31700	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KAM329_31710	COG0788	formyltetrahydrofolate deformylase activity
KAM329_31760	COG0741	lytic transglycosylase activity
KAM329_31760	COG0739	heme binding
KAM329_31760	COG1196	nuclear chromosome segregation
KAM329_31770	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KAM329_31780	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KAM329_31790	COG0673	inositol 2-dehydrogenase activity
KAM329_31840	COG1032	radical SAM domain protein
KAM329_31850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM329_31870	COG3706	GGDEF domain
KAM329_31880	COG1752	Esterase of the alpha-beta hydrolase superfamily
KAM329_31890	COG0733	neurotransmitter:sodium symporter activity
KAM329_31950	COG0281	malic enzyme
KAM329_31960	COG2207	Transcriptional regulator
KAM329_32000	COG2233	PERMEase
KAM329_32010	COG0095	Lipoate-protein ligase
KAM329_32020	COG1115	amino acid carrier protein
KAM329_32030	COG0019	diaminopimelate decarboxylase activity
KAM329_32050	COG0678	peroxiredoxin activity
KAM329_32060	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KAM329_32080	COG1126	abc transporter atp-binding protein
KAM329_32090	COG0765	amino acid transport
KAM329_32100	COG4597	amino acid ABC transporter
KAM329_32110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM329_32150	COG0545	Peptidyl-prolyl cis-trans isomerase
KAM329_32210	COG4783	chaperone-mediated protein folding
KAM329_32230	COG5002	protein histidine kinase activity
KAM329_32240	COG0745	RESPONSE REGULATOR receiver
KAM329_32250	COG0346	lactoylglutathione lyase activity
KAM329_32260	COG3706	GGDEF domain
KAM329_32270	COG3284	Transcriptional regulator
KAM329_32300	COG0697	spore germination
KAM329_32320	COG0667	Aldo Keto reductase
KAM329_32350	COG3290	protein histidine kinase activity
KAM329_32370	COG1566	PFAM secretion protein HlyD family protein
KAM329_32420	COG0602	queuosine metabolic process
KAM329_32430	COG1328	CTP reductase activity
KAM329_32450	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KAM329_32460	COG3115	cell septum assembly
KAM329_32470	COG1196	nuclear chromosome segregation
KAM329_32490	COG2860	membrane
KAM329_32510	COG3108	Peptidase M15
KAM329_32520	COG2989	Protein conserved in bacteria
KAM329_32550	COG0463	Glycosyl transferase, family 2
KAM329_32580	COG0366	Alpha amylase catalytic
KAM329_32670	COG3706	GGDEF domain
KAM329_32680	COG0037	tRNA processing
KAM329_32710	COG0488	(ABC) transporter
KAM329_32730	COG0531	amino acid
KAM329_32740	COG0814	amino acid
KAM329_32770	COG0825	malonyl-CoA metabolic process
KAM329_32780	COG0587	DNA-directed DNA polymerase activity
KAM329_32790	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KAM329_32800	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAM329_32810	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAM329_32820	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KAM329_32830	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAM329_32860	COG0750	zinc metalloprotease
KAM329_32870	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KAM329_32880	COG0575	Belongs to the CDS family
KAM329_32890	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KAM329_32900	COG0233	cytoplasmic translational termination
KAM329_32910	COG0528	UMP kinase activity
KAM329_32920	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KAM329_32930	COG0052	Belongs to the universal ribosomal protein uS2 family
KAM329_32940	COG0024	Methionine aminopeptidase
KAM329_32950	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KAM329_32960	COG2171	N-acyltransferase activity
KAM329_32980	COG1263	PTS System
KAM329_32980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM329_33000	COG4580	involved in the transport of maltose and maltodextrins
KAM329_33020	COG0564	pseudouridine synthase activity
KAM329_33030	COG3098	single-species biofilm formation
KAM329_33080	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
KAM329_33100	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KAM329_33100	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KAM329_33130	COG1611	Belongs to the LOG family
KAM329_33140	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KAM329_33150	COG0473	3-isopropylmalate dehydrogenase activity
KAM329_33170	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
KAM329_33180	COG2363	Small membrane protein
KAM329_33200	COG0583	DNA-binding transcription factor activity
KAM329_33210	COG0840	transmembrane signaling receptor activity
KAM329_33220	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KAM329_33250	COG1477	protein flavinylation
KAM329_33260	COG2871	sodium ion transport
KAM329_33270	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM329_33280	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM329_33290	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM329_33300	COG1805	sodium ion transport
KAM329_33310	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM329_33320	COG0271	Belongs to the BolA IbaG family
KAM329_33330	COG2813	Specifically methylates the guanine in position
KAM329_33350	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KAM329_33370	COG2211	Major facilitator Superfamily
KAM329_33390	COG1666	GTP binding
KAM329_33400	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KAM329_33420	COG1393	Belongs to the ArsC family
KAM329_33430	COG0798	PFAM Bile acid sodium symporter
KAM329_33450	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KAM329_33500	COG0582	viral genome integration into host DNA
KAM329_33520	COG3335	DDE superfamily endonuclease
KAM329_33550	COG3311	Transcriptional regulator
KAM329_33570	COG1196	nuclear chromosome segregation
KAM329_33760	COG2003	Belongs to the UPF0758 family
KAM329_33850	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KAM329_33880	COG2189	Belongs to the N(4) N(6)-methyltransferase family
KAM329_33910	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KAM329_33920	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KAM329_33930	COG1151	hydroxylamine reductase activity
KAM329_33940	COG0783	Belongs to the Dps family
KAM329_33990	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KAM329_34020	COG4221	oxidoreductase activity
KAM329_34040	COG0415	Belongs to the DNA photolyase family
KAM329_34050	COG0789	Transcriptional regulator
KAM329_34060	COG3272	Protein of unknown function (DUF1722)
KAM329_34110	COG1605	Chorismate mutase
KAM329_34110	COG0077	Prephenate dehydratase
KAM329_34180	COG3039	Transposase
KAM329_34290	COG1484	DNA-dependent DNA replication
KAM329_34300	COG4584	PFAM Integrase catalytic
KAM329_34320	COG2801	Transposase and inactivated derivatives
KAM329_34320	COG3415	Transposase
KAM329_34370	COG2916	Histone family protein nucleoid-structuring protein H-NS
KAM329_34400	COG3039	Transposase
KAM329_34470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KAM329_34550	COG4584	PFAM Integrase catalytic
KAM329_34580	COG2133	pyrroloquinoline quinone binding
KAM329_34600	COG1349	DNA-binding transcription factor activity
KAM329_34610	COG2084	Dehydrogenase
KAM329_34630	COG0235	Class ii aldolase
KAM329_34640	COG3622	Belongs to the hyi family
KAM329_34650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KAM329_34660	COG2610	gluconate transmembrane transporter activity
KAM329_34700	COG0300	oxidoreductase activity
KAM329_34750	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KAM329_34770	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KAM329_34790	COG3813	Protein conserved in bacteria
KAM329_34810	COG0826	peptidase U32
KAM329_34820	COG1280	lysine exporter protein (LysE YggA)
KAM329_34840	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KAM329_34880	COG3275	phosphorelay sensor kinase activity
KAM329_34890	COG3279	Response regulator of the LytR AlgR family
KAM329_34910	COG1966	Carbon starvation protein
KAM329_34970	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KAM329_35000	COG4263	nitrous-oxide reductase activity
KAM329_35010	COG0348	domain, Protein
KAM329_35010	COG3901	Regulator of nitric oxide reductase transcription
KAM329_35020	COG0114	fumarate hydratase activity
KAM329_35040	COG0506	proline dehydrogenase activity
KAM329_35040	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KAM329_35040	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KAM329_35050	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KAM329_35080	COG0737	Belongs to the 5'-nucleotidase family
KAM329_35120	COG2204	response regulator
KAM329_35130	COG0545	Peptidyl-prolyl cis-trans isomerase
KAM329_35150	COG2900	Belongs to the SlyX family
KAM329_35160	COG1047	Peptidyl-prolyl cis-trans
KAM329_35170	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KAM329_35190	COG0784	Response regulator, receiver
KAM329_35190	COG0835	chemotaxis
KAM329_35200	COG0429	hydrolase of the alpha beta-hydrolase fold
KAM329_35210	COG4251	negative regulation of phosphorylation
KAM329_35210	COG3706	GGDEF domain
KAM329_35210	COG2203	Gaf domain
KAM329_35210	COG5001	Diguanylate cyclase
KAM329_35220	COG3089	Belongs to the UPF0270 family
KAM329_35230	COG3954	Phosphoribulokinase
KAM329_35260	COG1765	OsmC-like protein
KAM329_35280	COG2226	methyltransferase
KAM329_35320	COG2205	protein histidine kinase activity
KAM329_35330	COG2814	Major facilitator Superfamily
KAM329_35380	COG0748	coenzyme F420 binding
KAM329_35390	COG3721	Heme iron utilization protein
KAM329_35410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAM329_35460	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KAM329_35480	COG0463	Glycosyl transferase, family 2
KAM329_35490	COG1196	nuclear chromosome segregation
KAM329_35490	COG0741	lytic transglycosylase activity
KAM329_35490	COG0739	heme binding
KAM329_35500	COG0488	(ABC) transporter
KAM329_35520	COG2252	PERMEase
KAM329_35530	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KAM329_35540	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KAM329_35550	COG3178	'Phosphotransferase
KAM329_35560	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KAM329_35580	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KAM329_35590	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KAM329_35600	COG2967	ApaG domain
KAM329_35610	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KAM329_35620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KAM329_35630	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KAM329_35640	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KAM329_35650	COG3314	Sporulation integral membrane protein YlbJ
KAM329_35660	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KAM329_35670	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KAM329_35680	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KAM329_35690	COG0142	geranyltranstransferase activity
KAM329_35700	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
KAM329_35710	COG0330	HflC and HflK could
KAM329_35720	COG0330	HflC and HflK could
KAM329_35730	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KAM329_35740	COG1923	regulation of RNA biosynthetic process
KAM329_35750	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KAM329_35760	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KAM329_35780	COG0802	atpase or kinase
KAM329_35790	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KAM329_35790	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KAM329_35830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KAM329_35840	COG2011	ABC-type metal ion transport system permease component
KAM329_35850	COG1464	Belongs to the NlpA lipoprotein family
KAM329_35890	COG0784	Response regulator, receiver
KAM329_35890	COG2198	Histidine kinase
KAM329_35890	COG2205	protein histidine kinase activity
KAM329_35890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM329_35930	COG2198	Histidine kinase
KAM329_35930	COG0784	Response regulator, receiver
KAM329_35930	COG5002	protein histidine kinase activity
KAM329_35970	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
KAM329_36000	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KAM329_36010	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
KAM329_36020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KAM329_36030	COG2716	regulation of RNA biosynthetic process
KAM329_36040	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KAM329_36050	COG3013	Belongs to the UPF0304 family
KAM329_36070	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KAM329_36080	COG0280	phosphate acetyltransferase
KAM329_36080	COG0857	belongs to the CobB CobQ family
KAM329_36110	COG4804	nuclease activity
KAM329_36140	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KAM329_36160	COG3077	Addiction module antitoxin, RelB DinJ family
KAM329_36170	COG3385	transposase activity
KAM329_36210	COG5489	Protein of unknown function (DUF736)
KAM329_36290	COG1192	Involved in chromosome partitioning
KAM329_36320	COG4959	Type IV secretory pathway protease TraF
KAM329_36360	COG1127	ABC transporter
KAM329_36370	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KAM329_36440	COG0583	DNA-binding transcription factor activity
KAM329_36490	COG3846	protein secretion by the type IV secretion system
KAM329_36520	COG3451	type IV secretory pathway VirB4
KAM329_36540	COG3838	Conjugal transfer protein Trbc
KAM329_36550	COG4962	Type ii secretion system protein e
KAM329_36610	COG2076	Multidrug Resistance protein
KAM329_36660	COG2003	Belongs to the UPF0758 family
KAM329_36670	COG4804	nuclease activity
KAM329_36730	COG4962	Type ii secretion system protein e
KAM329_36740	COG3838	Conjugal transfer protein Trbc
KAM329_36760	COG3451	type IV secretory pathway VirB4
KAM329_36840	COG0440	acetolactate synthase activity
KAM329_36850	COG0028	Belongs to the TPP enzyme family
KAM329_36880	COG0671	phosphoesterase, PA-phosphatase related
KAM329_36900	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KAM329_36910	COG0473	3-isopropylmalate dehydrogenase activity
KAM329_36920	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KAM329_36930	COG0066	3-isopropylmalate dehydratase activity
KAM329_36960	COG4143	(ABC) transporter
KAM329_36970	COG1178	ABC-type Fe3 transport system permease component
KAM329_36980	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
KAM329_37000	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KAM329_37020	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KAM329_37040	COG0316	Belongs to the HesB IscA family
KAM329_37060	COG0038	chloride channel
KAM329_37070	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KAM329_37100	COG0671	phosphoesterase, PA-phosphatase related
KAM329_37120	COG0583	DNA-binding transcription factor activity
KAM329_37130	COG2076	Multidrug Resistance protein
KAM329_37150	COG0346	lactoylglutathione lyase activity
KAM329_37160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KAM329_37170	COG1643	Atp-dependent helicase
KAM329_37190	COG1489	DNA binding
KAM329_37200	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KAM329_37210	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KAM329_37230	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KAM329_37240	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KAM329_37250	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KAM329_37270	COG0842	Transport permease protein
KAM329_37280	COG1131	(ABC) transporter
KAM329_37310	COG0163	prenyltransferase activity
KAM329_37320	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KAM329_37330	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KAM329_37360	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
KAM329_37390	COG1136	(ABC) transporter
KAM329_37510	COG2801	Transposase and inactivated derivatives
KAM329_37520	COG0529	Catalyzes the synthesis of activated sulfate
KAM329_37530	COG3273	potassium ion transport
KAM329_37530	COG0471	metal ion transport
KAM329_37540	COG2895	sulfate adenylyltransferase (ATP) activity
KAM329_37550	COG0175	sulfate reduction
KAM329_37560	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KAM329_37560	COG1648	precorrin-2 dehydrogenase activity
KAM329_37570	COG0330	HflC and HflK could
KAM329_37580	COG1585	Membrane protein implicated in regulation of membrane protease activity
KAM329_37600	COG0673	inositol 2-dehydrogenase activity
KAM329_37620	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KAM329_37630	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KAM329_37640	COG3036	rescue of stalled ribosome
KAM329_37670	COG0138	bifunctional purine biosynthesis protein purh
KAM329_37740	COG3335	DDE superfamily endonuclease
KAM329_37750	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KAM329_37760	COG0358	DNA primase activity
KAM329_37770	COG1610	YqeY-like protein
KAM329_37780	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KAM329_37790	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KAM329_37810	COG1388	LysM domain
KAM329_37810	COG4942	peptidase
KAM329_37820	COG1238	metal cluster binding
KAM329_37830	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KAM329_37840	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KAM329_37850	COG0585	pseudouridine synthase activity
KAM329_37870	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KAM329_37880	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KAM329_37890	COG0148	phosphopyruvate hydratase activity
KAM329_37900	COG0504	CTP synthase activity
KAM329_37910	COG3956	TIGRFAM MazG family protein
KAM329_37920	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KAM329_37930	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KAM329_37950	COG4807	Protein conserved in bacteria
KAM329_37960	COG3023	N-Acetylmuramoyl-L-alanine amidase
KAM329_37970	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KAM329_37980	COG1381	Involved in DNA repair and RecF pathway recombination
KAM329_38000	COG0571	ribonuclease III activity
KAM329_38010	COG0681	Belongs to the peptidase S26 family
KAM329_38020	COG0481	GTPase activity
KAM329_38050	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
KAM329_38060	COG1595	DNA-templated transcription, initiation
KAM329_38070	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KAM329_38090	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KAM329_38110	COG0583	DNA-binding transcription factor activity
KAM329_38170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAM329_38190	COG0126	phosphoglycerate kinase activity
KAM329_38200	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KAM329_38210	COG1940	carbohydrate kinase activity
KAM329_38220	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KAM329_38240	COG4991	sh3 domain protein
KAM329_38250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KAM329_38280	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KAM329_38290	COG1028	Short-chain dehydrogenase reductase Sdr
KAM329_38320	COG1505	serine-type exopeptidase activity
KAM329_38330	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KAM329_38340	COG0765	amino acid transport
KAM329_38350	COG0765	amino acid transport
KAM329_38360	COG1126	abc transporter atp-binding protein
KAM329_38370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM329_38380	COG3174	membrane
KAM329_38390	COG0110	maltose O-acetyltransferase activity
KAM329_38450	COG1942	4-Oxalocrotonate Tautomerase
KAM329_38470	COG0583	DNA-binding transcription factor activity
KAM329_38480	COG0165	Argininosuccinate lyase
KAM329_38490	COG0137	argininosuccinate synthase activity
KAM329_38510	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KAM329_38520	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KAM329_38540	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KAM329_38550	COG3447	MASE1 domain protein
KAM329_38550	COG5001	Diguanylate cyclase
KAM329_38550	COG5002	protein histidine kinase activity
KAM329_38560	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KAM329_38630	COG0583	DNA-binding transcription factor activity
KAM329_38640	COG1380	Effector of murein hydrolase LrgA
KAM329_38650	COG1346	cytolysis
KAM329_38660	COG0527	aspartate kinase activity
KAM329_38660	COG0460	homoserine dehydrogenase
KAM329_38670	COG0626	cystathionine gamma-synthase activity
KAM329_38700	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM329_38710	COG0814	amino acid
KAM329_38720	COG1218	3'(2'),5'-bisphosphate nucleotidase
KAM329_38730	COG0494	nUDIX hydrolase
KAM329_38740	COG1011	Hydrolase
KAM329_38750	COG1902	pentaerythritol trinitrate reductase activity
KAM329_38770	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KAM329_38800	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
KAM329_38820	COG3156	type II secretion system protein K
KAM329_38830	COG4795	General secretion pathway protein
KAM329_38840	COG2165	general secretion pathway protein
KAM329_38860	COG2165	general secretion pathway protein
KAM329_38870	COG1459	type II secretion system
KAM329_38880	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KAM329_38900	COG3031	protein transport across the cell outer membrane
KAM329_38920	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KAM329_38930	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KAM329_38970	COG3133	Outer membrane lipoprotein
KAM329_38980	COG3025	triphosphatase activity
KAM329_38990	COG1392	Phosphate transport regulator
KAM329_39000	COG0306	phosphate transporter
KAM329_39010	COG0617	tRNA 3'-terminal CCA addition
KAM329_39020	COG3267	Type II secretory pathway component ExeA
KAM329_39020	COG3409	Peptidoglycan-binding domain 1 protein
KAM329_39040	COG1194	a g-specific adenine glycosylase
KAM329_39050	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
KAM329_39080	COG3240	lipase activity
KAM329_39100	COG3009	Protein conserved in bacteria
KAM329_39110	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KAM329_39110	COG3008	intermembrane lipid transfer
KAM329_39120	COG2995	paraquat-inducible protein a
KAM329_39140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAM329_39150	COG4251	negative regulation of phosphorylation
KAM329_39150	COG5001	Diguanylate cyclase
KAM329_39150	COG2203	Gaf domain
KAM329_39150	COG3706	GGDEF domain
KAM329_39160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KAM329_39170	COG2813	Specifically methylates the guanine in position
KAM329_39180	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KAM329_39190	COG0297	glycogen (starch) synthase activity
KAM329_39220	COG1757	Na H antiporter
KAM329_39230	COG0583	DNA-binding transcription factor activity
KAM329_39240	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KAM329_39250	COG3842	ATPase activity
KAM329_39260	COG1176	ABC-type spermidine putrescine transport system, permease component I
KAM329_39270	COG1177	transmembrane transport
KAM329_39280	COG1012	belongs to the aldehyde dehydrogenase family
KAM329_39290	COG0109	protoheme IX farnesyltransferase activity
KAM329_39350	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KAM329_39370	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KAM329_39370	COG1565	acr, cog1565
KAM329_39380	COG1444	tRNA N-acetyltransferase activity
KAM329_39420	COG1803	Methylglyoxal synthase
KAM329_39450	COG0252	asparaginase activity
KAM329_39490	COG1263	PTS System
KAM329_39490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM329_39500	COG0366	Alpha amylase catalytic
KAM329_39510	COG0110	maltose O-acetyltransferase activity
KAM329_39520	COG1522	sequence-specific DNA binding
KAM329_39580	COG3068	Protein conserved in bacteria
KAM329_39600	COG0739	heme binding
KAM329_39640	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
KAM329_39650	COG1121	(ABC) transporter
KAM329_39660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KAM329_39670	COG0583	DNA-binding transcription factor activity
KAM329_39690	COG1573	uracil-dna glycosylase
KAM329_39700	COG2962	Rard protein
KAM329_39710	COG2827	Endonuclease containing a URI domain
KAM329_39740	COG1842	Phage shock protein A
KAM329_39750	COG0204	Acyl-transferase
KAM329_39790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KAM329_39810	COG0484	heat shock protein binding
KAM329_39890	COG5433	transposase activity
KAM329_39910	COG3039	Transposase
KAM329_39990	COG1289	transmembrane transporter activity
KAM329_40000	COG1566	PFAM secretion protein HlyD family protein
KAM329_40030	COG1051	belongs to the nudix hydrolase family
KAM329_40040	COG3150	esterase
KAM329_40060	COG3151	Protein conserved in bacteria
KAM329_40070	COG0494	nUDIX hydrolase
KAM329_40080	COG1538	Outer membrane efflux protein
KAM329_40100	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KAM329_40100	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KAM329_40110	COG1560	Kdo2-lipid A biosynthetic process
KAM329_40140	COG2771	luxR family
KAM329_40150	COG3916	Acyl-homoserine-lactone synthase
KAM329_40170	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
KAM329_40180	COG2213	PTS system mannitol-specific
KAM329_40180	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM329_40190	COG0246	Mannitol dehydrogenase
KAM329_40200	COG3722	fumarate hydratase activity
KAM329_40210	COG3263	regulation of cellular component size
KAM329_40250	COG1671	Belongs to the UPF0178 family
KAM329_40280	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KAM329_40290	COG0513	Belongs to the DEAD box helicase family
KAM329_40330	COG1575	Belongs to the MenA family. Type 1 subfamily
KAM329_40340	COG1169	isochorismate synthase
KAM329_40350	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KAM329_40360	COG0596	Alpha beta hydrolase
KAM329_40370	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KAM329_40390	COG0318	PFAM AMP-dependent synthetase and ligase
KAM329_40400	COG3291	Pkd domain containing protein
KAM329_40410	COG2949	membrane
KAM329_40420	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KAM329_40440	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KAM329_40500	COG2873	o-acetylhomoserine
KAM329_40520	COG1979	alcohol dehydrogenase
KAM329_40550	COG4221	oxidoreductase activity
KAM329_40590	COG1285	pathogenesis
KAM329_40620	COG1368	sulfuric ester hydrolase activity
KAM329_40630	COG1522	sequence-specific DNA binding
KAM329_40650	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KAM329_40670	COG1058	Belongs to the CinA family
KAM329_40670	COG1546	Belongs to the CinA family
KAM329_40680	COG1988	membrane-bound metal-dependent
KAM329_40700	COG0561	phosphatase activity
KAM329_40710	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KAM329_40730	COG1011	Hydrolase
KAM329_40760	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KAM329_40770	COG0019	diaminopimelate decarboxylase activity
KAM329_40790	COG1965	Belongs to the frataxin family
KAM329_40800	COG0400	carboxylic ester hydrolase activity
KAM329_40810	COG3072	Adenylate cyclase
KAM329_40820	COG0181	hydroxymethylbilane synthase activity
KAM329_40840	COG2959	enzyme of heme biosynthesis
KAM329_40850	COG3071	HemY protein
KAM329_40870	COG0312	modulator of DNA gyrase
KAM329_40880	COG3028	Belongs to the UPF0307 family
KAM329_40900	COG2926	Belongs to the UPF0265 family
KAM329_40920	COG1396	sequence-specific DNA binding
KAM329_40930	COG3135	benzoate transporter
KAM329_41000	COG3047	cAMP biosynthetic process
KAM329_41020	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KAM329_41030	COG2197	response regulator
KAM329_41090	COG5642	Protein of unknown function (DUF2384)
KAM329_41110	COG5433	transposase activity
KAM329_41120	COG5433	transposase activity
KAM329_41130	COG3328	transposase activity
KAM329_41140	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM329_41240	COG0457	Tetratricopeptide repeat
KAM329_41250	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KAM329_41260	COG1215	transferase activity, transferring glycosyl groups
KAM329_41270	COG0455	bacterial-type flagellum organization
KAM329_41310	COG5499	transcription regulator containing HTH domain
KAM329_41320	COG2916	Histone family protein nucleoid-structuring protein H-NS
KAM329_41340	COG3039	Transposase
KAM329_41470	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KAM329_41480	COG5642	Protein of unknown function (DUF2384)
KAM329_41490	COG2801	Transposase and inactivated derivatives
KAM329_41510	COG1484	DNA-dependent DNA replication
KAM329_41520	COG1484	DNA-dependent DNA replication
KAM329_41530	COG4584	PFAM Integrase catalytic
KAM329_41550	COG5499	transcription regulator containing HTH domain
KAM329_41640	COG0210	DNA helicase
KAM329_41680	COG2850	peptidyl-arginine hydroxylation
KAM329_41720	COG2916	Histone family protein nucleoid-structuring protein H-NS
KAM329_41810	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KAM329_41820	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KAM329_41880	COG1396	sequence-specific DNA binding
KAM329_41940	COG1278	Cold shock
KAM329_42000	COG3706	GGDEF domain
KAM329_42010	COG0347	Belongs to the P(II) protein family
KAM329_42020	COG0004	ammonium transporteR
KAM329_42060	COG0346	lactoylglutathione lyase activity
KAM329_42090	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KAM329_42100	COG1074	ATP-dependent DNA helicase activity
KAM329_42110	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KAM329_42120	COG2259	Doxx family
KAM329_42130	COG1741	Belongs to the pirin family
KAM329_42150	COG0583	DNA-binding transcription factor activity
KAM329_42200	COG1175	transmembrane transport
KAM329_42220	COG3842	ATPase activity
KAM329_42280	COG0456	acetyltransferase
KAM329_42290	COG0753	catalase activity
KAM329_42330	COG0494	nUDIX hydrolase
KAM329_42340	COG0628	permease
KAM329_42360	COG2957	Belongs to the agmatine deiminase family
KAM329_42390	COG2957	Belongs to the agmatine deiminase family
KAM329_42400	COG0583	DNA-binding transcription factor activity
KAM329_42430	COG1461	Dihydroxyacetone kinase
KAM329_42440	COG2376	Dihydroxyacetone kinase
KAM329_42450	COG2252	PERMEase
KAM329_42460	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KAM329_42470	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KAM329_42480	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KAM329_42490	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KAM329_42500	COG0049	tRNA binding
KAM329_42510	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KAM329_42540	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KAM329_42550	COG0251	oxidation-reduction process
KAM329_42560	COG2964	Protein conserved in bacteria
KAM329_42570	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KAM329_42580	COG0085	RNA polymerase activity
KAM329_42590	COG0222	ribosome binding
KAM329_42600	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KAM329_42610	COG0081	regulation of translation
KAM329_42620	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KAM329_42630	COG0250	Participates in transcription elongation, termination and antitermination
KAM329_42650	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KAM329_42680	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KAM329_42690	COG0569	domain protein
KAM329_42700	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KAM329_42710	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KAM329_42720	COG3005	denitrification pathway
KAM329_42730	COG0243	molybdopterin cofactor binding
KAM329_42800	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KAM329_42820	COG2204	response regulator
KAM329_42840	COG2205	protein histidine kinase activity
KAM329_42870	COG0517	IMP dehydrogenase activity
KAM329_42870	COG0516	GMP reductase activity
KAM329_42890	COG1522	sequence-specific DNA binding
KAM329_42900	COG2502	aspartate--ammonia ligase
KAM329_42930	COG0583	DNA-binding transcription factor activity
KAM329_42940	COG0542	response to heat
KAM329_42960	COG0564	pseudouridine synthase activity
KAM329_42970	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAM329_42980	COG3681	Belongs to the UPF0597 family
KAM329_42990	COG2964	Protein conserved in bacteria
KAM329_43000	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KAM329_43010	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KAM329_43020	COG1979	alcohol dehydrogenase
KAM329_43030	COG2207	Transcriptional regulator
KAM329_43040	COG3040	lipid binding
KAM329_43080	COG0583	DNA-binding transcription factor activity
KAM329_43110	COG0540	Belongs to the ATCase OTCase family
KAM329_43120	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
KAM329_43130	COG1438	arginine binding
KAM329_43140	COG1288	antiporter activity
KAM329_43150	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KAM329_43230	COG3250	beta-galactosidase activity
KAM329_43250	COG1609	Transcriptional regulator
KAM329_43260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KAM329_43280	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KAM329_43290	COG2017	converts alpha-aldose to the beta-anomer
KAM329_43300	COG0667	Aldo Keto reductase
KAM329_43310	COG1968	undecaprenyl-diphosphatase activity
KAM329_43320	COG3806	Anti-sigma factor
KAM329_43330	COG1595	DNA-templated transcription, initiation
KAM329_43370	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KAM329_43380	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KAM329_43390	COG0477	Major facilitator Superfamily
KAM329_43420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM329_43430	COG1131	(ABC) transporter
KAM329_43440	COG0842	Transport permease protein
KAM329_43450	COG0842	Transport permease protein
KAM329_43460	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KAM329_43480	COG2116	formate transmembrane transporter activity
KAM329_43490	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KAM329_43490	COG1648	precorrin-2 dehydrogenase activity
KAM329_43500	COG2239	Acts as a magnesium transporter
KAM329_43510	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KAM329_43530	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KAM329_43550	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KAM329_43570	COG0514	ATP-dependent DNA helicase (RecQ)
KAM329_43580	COG2050	protein possibly involved in aromatic compounds catabolism
KAM329_43600	COG2258	MOSC domain
KAM329_43610	COG1177	transmembrane transport
KAM329_43620	COG1176	ABC-type spermidine putrescine transport system, permease component I
KAM329_43630	COG3842	ATPase activity
KAM329_43670	COG0174	glutamine synthetase
KAM329_43710	COG3045	CreA protein
KAM329_43720	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KAM329_43730	COG0443	Heat shock 70 kDa protein
KAM329_43760	COG0366	Alpha amylase catalytic
KAM329_43790	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KAM329_43800	COG0745	RESPONSE REGULATOR receiver
KAM329_43810	COG2205	protein histidine kinase activity
KAM329_43830	COG0281	malic enzyme
KAM329_43840	COG0702	epimerase
KAM329_43850	COG0254	rRNA binding
KAM329_43860	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KAM329_43910	COG0129	dihydroxy-acid dehydratase activity
KAM329_43930	COG3978	acetolactate synthase activity
KAM329_43950	COG0606	chelatase, subunit chli
KAM329_43960	COG0204	Acyl-transferase
KAM329_43970	COG0204	Acyl-transferase
KAM329_43980	COG1683	Conserved Protein
KAM329_44000	COG1335	isochorismatase
KAM329_44020	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KAM329_44030	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KAM329_44050	COG3084	Protein conserved in bacteria
KAM329_44060	COG4251	negative regulation of phosphorylation
KAM329_44060	COG5001	Diguanylate cyclase
KAM329_44060	COG2203	Gaf domain
KAM329_44060	COG3706	GGDEF domain
KAM329_44090	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KAM329_44100	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KAM329_44110	COG1561	YicC-like family, N-terminal region
KAM329_44130	COG1519	Transferase
KAM329_44140	COG0859	PFAM glycosyl transferase family 9
KAM329_44160	COG0463	Glycosyl transferase, family 2
KAM329_44170	COG0859	PFAM glycosyl transferase family 9
KAM329_44180	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KAM329_44190	COG2990	Protein conserved in bacteria
KAM329_44200	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KAM329_44220	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KAM329_44230	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KAM329_44240	COG2003	Belongs to the UPF0758 family
KAM329_44250	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KAM329_44260	COG0756	dUTP diphosphatase activity
KAM329_44270	COG1309	transcriptional regulator
KAM329_44280	COG0668	transmembrane transport
KAM329_44300	COG0166	Belongs to the GPI family
KAM329_44310	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KAM329_44320	COG0583	DNA-binding transcription factor activity
KAM329_44340	COG0045	succinate-CoA ligase (ADP-forming) activity
KAM329_44340	COG1042	CoA-binding domain protein
KAM329_44340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KAM329_44350	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
KAM329_44360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KAM329_44370	COG1739	Uncharacterized protein family UPF0029
KAM329_44380	COG0006	proline dipeptidase activity
KAM329_44390	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KAM329_44400	COG1250	3-hydroxyacyl-CoA dehydrogenase
KAM329_44400	COG1024	Enoyl-CoA hydratase
KAM329_44410	COG0183	Belongs to the thiolase family
KAM329_44460	COG0425	Belongs to the sulfur carrier protein TusA family
KAM329_44470	COG0251	oxidation-reduction process
KAM329_44480	COG2885	chlorophyll binding
KAM329_44510	COG1335	isochorismatase
KAM329_44520	COG2818	Glycosylase
KAM329_44530	COG0752	glycyl-tRNA synthetase alpha subunit
KAM329_44540	COG0751	glycine-tRNA ligase activity
KAM329_44570	COG4251	negative regulation of phosphorylation
KAM329_44570	COG3706	GGDEF domain
KAM329_44570	COG2203	Gaf domain
KAM329_44570	COG5001	Diguanylate cyclase
KAM329_44610	COG0814	amino acid
KAM329_44620	COG0814	amino acid
KAM329_44630	COG3033	Beta-eliminating lyase
KAM329_44640	COG0348	domain, Protein
KAM329_44660	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAM329_44670	COG1773	rubredoxin
KAM329_44670	COG0426	domain, Protein
KAM329_44680	COG3604	Transcriptional regulator
KAM329_44690	COG1609	Transcriptional regulator
KAM329_44770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KAM329_44800	COG2960	long-chain fatty acid transporting porin activity
KAM329_44820	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KAM329_44850	COG3118	belongs to the thioredoxin family
KAM329_44860	COG0513	Belongs to the DEAD box helicase family
KAM329_44870	COG0248	Ppx GppA phosphatase
KAM329_44890	COG0742	ribosomal rna small subunit methyltransferase
KAM329_44930	COG0084	hydrolase, TatD family'
KAM329_44940	COG0805	protein transport
KAM329_44950	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KAM329_44960	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KAM329_44970	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KAM329_44980	COG3165	ubiquinone biosynthetic process from chorismate
KAM329_45000	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KAM329_45010	COG0402	S-adenosylhomocysteine deaminase activity
KAM329_45030	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KAM329_45040	COG0848	biopolymer transport protein
KAM329_45050	COG0811	peptide transport
KAM329_45060	COG0811	peptide transport
KAM329_45080	COG2771	luxR family
KAM329_45170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KAM329_45180	COG0443	Heat shock 70 kDa protein
KAM329_45250	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KAM329_45260	COG1349	DNA-binding transcription factor activity
KAM329_45270	COG0745	RESPONSE REGULATOR receiver
KAM329_45280	COG2205	protein histidine kinase activity
KAM329_45300	COG4452	Inner membrane protein CreD
KAM329_45310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KAM329_45320	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KAM329_45330	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KAM329_45340	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KAM329_45350	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KAM329_45360	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KAM329_45370	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KAM329_45390	COG0356	it plays a direct role in the translocation of protons across the membrane
KAM329_45410	COG1475	DNA binding
KAM329_45420	COG1192	Involved in chromosome partitioning
KAM329_45430	COG0357	Ribosomal RNA small subunit methyltransferase G
KAM329_45440	COG0445	tRNA wobble uridine modification
KAM329_45450	COG0716	FMN binding
KAM329_45460	COG4774	siderophore transport
KAM329_45470	COG4615	Cyclic peptide transporter
KAM329_45480	COG1120	ATPase activity
KAM329_45490	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KAM329_45510	COG3550	peptidyl-serine autophosphorylation
KAM329_45550	COG2801	Transposase and inactivated derivatives
KAM329_45570	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KAM329_45580	COG0706	membrane insertase activity
KAM329_45590	COG0594	ribonuclease P activity
KAM329_45600	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KAM329_45610	COG1126	abc transporter atp-binding protein
KAM329_45690	COG1192	Involved in chromosome partitioning
KAM329_45770	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KAM329_45880	COG0419	ATPase involved in DNA repair
KAM329_45930	COG3550	peptidyl-serine autophosphorylation
KAM329_46120	COG0776	regulation of translation
KAM329_46160	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KAM329_46320	COG1192	Involved in chromosome partitioning
KAM329_46380	COG0358	DNA primase activity
KAM329_46420	COG1923	regulation of RNA biosynthetic process
KAM329_46480	COG5301	cellulose 1,4-beta-cellobiosidase activity
KAM329_46780	COG0556	nucleotide-excision repair
KAM329_46860	COG3039	Transposase
KAM329_46890	COG4974	Belongs to the 'phage' integrase family
KAM329_47230	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KAM329_47260	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM329_47350	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM329_47470	COG2948	multi-organism process
KAM329_47490	COG3504	Conjugal transfer protein
KAM329_47510	COG3451	type IV secretory pathway VirB4
KAM329_47530	COG3838	Conjugal transfer protein Trbc
KAM329_47540	COG4962	Type ii secretion system protein e
KAM329_47560	COG3041	Addiction module toxin RelE StbE family
KAM329_47570	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM329_47600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM329_47660	COG1192	Involved in chromosome partitioning
KAM329_47730	COG1192	Involved in chromosome partitioning
KAM329_47810	COG2176	DNA-directed DNA polymerase activity
KAM329_47810	COG5002	protein histidine kinase activity