locus-tag	class	description
KAM329_000010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KAM329_000020	COG0592	DNA-directed DNA polymerase activity
KAM329_000040	COG0187	DNA topoisomerase II activity
KAM329_000050	COG2207	Transcriptional regulator
KAM329_000060	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KAM329_000070	COG0071	Belongs to the small heat shock protein (HSP20) family
KAM329_000080	COG0071	Belongs to the small heat shock protein (HSP20) family
KAM329_000090	COG3977	Valine--pyruvate aminotransferase
KAM329_000120	COG2814	Major facilitator Superfamily
KAM329_000130	COG0745	RESPONSE REGULATOR receiver
KAM329_000140	COG2205	protein histidine kinase activity
KAM329_000180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KAM329_000190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM329_000190	COG4191	Histidine kinase
KAM329_000200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM329_000210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM329_000220	COG1309	transcriptional regulator
KAM329_000240	COG0561	phosphatase activity
KAM329_000250	COG2267	carboxylic ester hydrolase activity
KAM329_000260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KAM329_000270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KAM329_000280	COG1758	RNA polymerase activity
KAM329_000300	COG0859	PFAM glycosyl transferase family 9
KAM329_000310	COG3642	lipopolysaccharide core region biosynthetic process
KAM329_000400	COG3335	DDE superfamily endonuclease
KAM329_000410	COG0589	response to stress
KAM329_000430	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KAM329_000440	COG3706	GGDEF domain
KAM329_000450	COG1528	Iron-storage protein
KAM329_000460	COG2081	HI0933 family
KAM329_000470	COG2223	nitrite transmembrane transporter activity
KAM329_000480	COG1280	lysine exporter protein (LysE YggA)
KAM329_000510	COG3188	usher protein
KAM329_000540	COG2197	response regulator
KAM329_000550	COG2205	protein histidine kinase activity
KAM329_000550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM329_000570	COG3275	phosphorelay sensor kinase activity
KAM329_000580	COG3279	Response regulator of the LytR AlgR family
KAM329_000590	COG2223	nitrite transmembrane transporter activity
KAM329_000600	COG3385	transposase activity
KAM329_000610	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KAM329_000620	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KAM329_000660	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KAM329_000670	COG2166	iron-sulfur cluster assembly
KAM329_000680	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KAM329_000720	COG1063	alcohol dehydrogenase
KAM329_000750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KAM329_000840	COG1609	Transcriptional regulator
KAM329_000880	COG1580	Controls the rotational direction of flagella during chemotaxis
KAM329_000890	COG3161	chorismate lyase activity
KAM329_000900	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KAM329_000910	COG2937	Belongs to the GPAT DAPAT family
KAM329_000920	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KAM329_000950	COG0534	Mate efflux family protein
KAM329_000960	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KAM329_000970	COG2205	protein histidine kinase activity
KAM329_000980	COG0745	RESPONSE REGULATOR receiver
KAM329_001000	COG1045	serine acetyltransferase
KAM329_001020	COG3074	FtsZ-dependent cytokinesis
KAM329_001030	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
KAM329_001040	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KAM329_001040	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KAM329_001050	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KAM329_001060	COG1609	Transcriptional regulator
KAM329_001070	COG3250	beta-galactosidase activity
KAM329_001080	COG2731	YhcH YjgK YiaL family protein
KAM329_001090	COG0531	amino acid
KAM329_001100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM329_001110	COG0531	amino acid
KAM329_001120	COG0385	Bile acid
KAM329_001130	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KAM329_001180	COG0583	DNA-binding transcription factor activity
KAM329_001190	COG1079	Belongs to the binding-protein-dependent transport system permease family
KAM329_001210	COG4603	Belongs to the binding-protein-dependent transport system permease family
KAM329_001220	COG3845	ABC transporter
KAM329_001230	COG1744	ABC transporter substrate-binding protein PnrA-like
KAM329_001260	COG0210	DNA helicase
KAM329_001290	COG1943	Transposase
KAM329_001300	COG0583	DNA-binding transcription factor activity
KAM329_001400	COG1280	lysine exporter protein (LysE YggA)
KAM329_001420	COG2962	Rard protein
KAM329_001440	COG1012	belongs to the aldehyde dehydrogenase family
KAM329_001450	COG1396	sequence-specific DNA binding
KAM329_001460	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KAM329_001480	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KAM329_001480	COG0519	Catalyzes the synthesis of GMP from XMP
KAM329_001500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM329_001540	COG1322	Protein conserved in bacteria
KAM329_001550	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KAM329_001560	COG0569	domain protein
KAM329_001570	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KAM329_001570	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KAM329_001580	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KAM329_001590	COG0242	peptide deformylase activity
KAM329_001610	COG0758	DNA mediated transformation
KAM329_001620	COG2922	Belongs to the Smg family
KAM329_001630	COG0551	DNA topoisomerase type I activity
KAM329_001640	COG0009	L-threonylcarbamoyladenylate synthase
KAM329_001650	COG0408	coproporphyrinogen oxidase activity
KAM329_001660	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KAM329_001680	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KAM329_001710	COG3078	GTPase activator activity
KAM329_001730	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KAM329_001750	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KAM329_001770	COG3852	Histidine kinase
KAM329_001790	COG0174	glutamine synthetase
KAM329_001800	COG1217	gtp-binding protein TYPA
KAM329_001820	COG1295	ribonuclease BN
KAM329_001830	COG1490	D-aminoacyl-tRNA deacylase activity
KAM329_001850	COG0456	acetyltransferase
KAM329_001870	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KAM329_001880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KAM329_001890	COG2610	gluconate transmembrane transporter activity
KAM329_001900	COG3265	gluconokinase activity
KAM329_001910	COG0129	dihydroxy-acid dehydratase activity
KAM329_001920	COG0800	Aldolase
KAM329_001950	COG1609	Transcriptional regulator
KAM329_001970	COG4942	peptidase
KAM329_001980	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KAM329_001990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KAM329_002000	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KAM329_002010	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KAM329_002020	COG0316	Belongs to the HesB IscA family
KAM329_002020	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KAM329_002030	COG1040	competence protein
KAM329_002040	COG0596	Alpha beta hydrolase
KAM329_002070	COG2183	response to ionizing radiation
KAM329_002080	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KAM329_002100	COG2205	protein histidine kinase activity
KAM329_002120	COG0051	transcription antitermination factor activity, RNA binding
KAM329_002130	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KAM329_002140	COG0088	Forms part of the polypeptide exit tunnel
KAM329_002150	COG0089	rRNA binding
KAM329_002160	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KAM329_002170	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KAM329_002180	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KAM329_002190	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KAM329_002200	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KAM329_002210	COG0255	Belongs to the universal ribosomal protein uL29 family
KAM329_002220	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KAM329_002230	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KAM329_002240	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KAM329_002250	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KAM329_002260	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KAM329_002270	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KAM329_002280	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KAM329_002290	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KAM329_002300	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KAM329_002310	COG1841	ribosomal large subunit assembly
KAM329_002320	COG0200	Binds to the 23S rRNA
KAM329_002330	COG0201	protein transport
KAM329_002340	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KAM329_002350	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KAM329_002360	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KAM329_002370	COG0202	RNA polymerase activity
KAM329_002380	COG0203	ribosomal protein L17
KAM329_002410	COG3335	DDE superfamily endonuclease
KAM329_002420	COG1484	DNA-dependent DNA replication
KAM329_002430	COG1484	DNA-dependent DNA replication
KAM329_002440	COG4584	PFAM Integrase catalytic
KAM329_002460	COG4584	PFAM Integrase catalytic
KAM329_002520	COG2249	NAD(P)H dehydrogenase (quinone) activity
KAM329_002530	COG0583	DNA-binding transcription factor activity
KAM329_002550	COG0675	Transposase, IS605 OrfB family
KAM329_002560	COG4221	oxidoreductase activity
KAM329_002590	COG1770	oligopeptidase
KAM329_002600	COG2358	TRAP transporter, solute receptor (TAXI family
KAM329_002630	COG3714	YhhN family
KAM329_002660	COG0583	DNA-binding transcription factor activity
KAM329_002690	COG1301	dicarboxylic acid transport
KAM329_002710	COG2095	MarC family integral membrane protein
KAM329_002730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KAM329_002750	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KAM329_002760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KAM329_002820	COG0742	ribosomal rna small subunit methyltransferase
KAM329_002830	COG0552	protein localization to endoplasmic reticulum
KAM329_002840	COG2884	Cell division ATP-binding protein ftsE
KAM329_002850	COG2177	Part of the ABC transporter FtsEX involved in
KAM329_002870	COG0288	reversible hydration of carbon dioxide
KAM329_002880	COG2188	Transcriptional regulator
KAM329_002890	COG1228	amidohydrolase
KAM329_002900	COG0010	Belongs to the arginase family
KAM329_002910	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KAM329_002920	COG2986	histidine ammonia-lyase
KAM329_002930	COG0387	Pfam Sodium calcium exchanger
KAM329_002940	COG2200	EAL domain
KAM329_003040	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KAM329_003050	COG1459	type II secretion system
KAM329_003070	COG2165	general secretion pathway protein
KAM329_003080	COG2165	general secretion pathway protein
KAM329_003140	COG1077	Cell shape determining protein MreB Mrl
KAM329_003150	COG1792	Involved in formation and maintenance of cell shape
KAM329_003160	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KAM329_003170	COG0424	maF-like protein
KAM329_003180	COG1530	ribonuclease E activity
KAM329_003190	COG3164	Protein of unknown function
KAM329_003210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KAM329_003220	COG0312	modulator of DNA gyrase
KAM329_003250	COG0477	Major facilitator Superfamily
KAM329_003270	COG2321	neutral zinc metallopeptidase
KAM329_003290	COG0675	Transposase, IS605 OrfB family
KAM329_003360	COG0189	ligase activity
KAM329_003370	COG0642	Histidine kinase
KAM329_003380	COG0745	RESPONSE REGULATOR receiver
KAM329_003410	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KAM329_003420	COG0352	thiamine-phosphate diphosphorylase activity
KAM329_003430	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KAM329_003450	COG2022	thiamine diphosphate biosynthetic process
KAM329_003460	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KAM329_003490	COG3932	Exopolysaccharide synthesis, ExoD
KAM329_003520	COG1733	regulation of RNA biosynthetic process
KAM329_003530	COG0456	acetyltransferase
KAM329_003590	COG2226	methyltransferase
KAM329_003610	COG1494	fructose-1,6-bisphosphatase
KAM329_003630	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KAM329_003640	COG5007	Belongs to the BolA IbaG family
KAM329_003660	COG2854	intermembrane phospholipid transfer
KAM329_003670	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KAM329_003680	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KAM329_003690	COG1127	ABC transporter
KAM329_003700	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KAM329_003700	COG0517	IMP dehydrogenase activity
KAM329_003710	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KAM329_003730	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KAM329_003740	COG1137	ATPase activity
KAM329_003750	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KAM329_003770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM329_003780	COG1660	Displays ATPase and GTPase activities
KAM329_003790	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM329_003830	COG3964	amidohydrolase
KAM329_003890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KAM329_003900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KAM329_003920	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KAM329_003930	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KAM329_003940	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KAM329_003950	COG0723	plastoquinol--plastocyanin reductase activity
KAM329_003960	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KAM329_003970	COG2857	Cytochrome c1
KAM329_003980	COG0625	glutathione transferase activity
KAM329_003990	COG2969	positive regulation of protein catabolic process
KAM329_004010	COG2823	Periplasmic or secreted lipoprotein
KAM329_004020	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KAM329_004030	COG0792	nuclease activity
KAM329_004040	COG3107	peptidoglycan biosynthetic process
KAM329_004050	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KAM329_004060	COG2001	Belongs to the MraZ family
KAM329_004070	COG0275	rRNA processing
KAM329_004080	COG3116	cell division
KAM329_004090	COG0768	penicillin binding
KAM329_004100	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KAM329_004110	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KAM329_004120	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KAM329_004130	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KAM329_004140	COG0772	Belongs to the SEDS family
KAM329_004150	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KAM329_004160	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KAM329_004170	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KAM329_004180	COG0849	cell division
KAM329_004190	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KAM329_004200	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KAM329_004220	COG0653	protein targeting
KAM329_004240	COG0494	nUDIX hydrolase
KAM329_004250	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KAM329_004260	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
KAM329_004290	COG1459	type II secretion system
KAM329_004300	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KAM329_004360	COG2186	Transcriptional regulator
KAM329_004370	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KAM329_004380	COG0508	dehydrogenase complex catalyzes the overall conversion of
KAM329_004390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KAM329_004410	COG0840	transmembrane signaling receptor activity
KAM329_004420	COG1752	Esterase of the alpha-beta hydrolase superfamily
KAM329_004430	COG1049	propionate catabolic process, 2-methylcitrate cycle
KAM329_004440	COG2200	EAL domain
KAM329_004450	COG2771	luxR family
KAM329_004450	COG2200	EAL domain
KAM329_004480	COG1280	lysine exporter protein (LysE YggA)
KAM329_004500	COG0523	cobalamin synthesis protein
KAM329_004530	COG0477	Major facilitator Superfamily
KAM329_004560	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KAM329_004570	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KAM329_004580	COG3335	DDE superfamily endonuclease
KAM329_004640	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KAM329_004660	COG1546	Belongs to the CinA family
KAM329_004670	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KAM329_004680	COG2137	regulation of response to DNA damage stimulus
KAM329_004690	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KAM329_004700	COG0527	aspartate kinase activity
KAM329_004710	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KAM329_004720	COG1686	Belongs to the peptidase S11 family
KAM329_004730	COG0586	Pfam SNARE associated Golgi protein
KAM329_004740	COG1253	flavin adenine dinucleotide binding
KAM329_004750	COG0525	valine-tRNA ligase activity
KAM329_004770	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KAM329_004780	COG0795	lipopolysaccharide-transporting ATPase activity
KAM329_004790	COG0795	lipopolysaccharide-transporting ATPase activity
KAM329_004810	COG0582	viral genome integration into host DNA
KAM329_004940	COG1196	nuclear chromosome segregation
KAM329_004990	COG2801	Transposase and inactivated derivatives
KAM329_005050	COG0004	ammonium transporteR
KAM329_005060	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KAM329_005090	COG2165	general secretion pathway protein
KAM329_005100	COG0084	hydrolase, TatD family'
KAM329_005110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KAM329_005130	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KAM329_005140	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KAM329_005150	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KAM329_005160	COG0813	purine-nucleoside phosphorylase activity
KAM329_005170	COG3447	MASE1 domain protein
KAM329_005170	COG5001	Diguanylate cyclase
KAM329_005170	COG5002	protein histidine kinase activity
KAM329_005190	COG0560	Phosphoserine phosphatase
KAM329_005210	COG3385	transposase activity
KAM329_005230	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KAM329_005250	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
KAM329_005260	COG0776	regulation of translation
KAM329_005290	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KAM329_005300	COG0735	belongs to the Fur family
KAM329_005340	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KAM329_005350	COG0513	Belongs to the DEAD box helicase family
KAM329_005360	COG3022	response to hydroperoxide
KAM329_005390	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KAM329_005400	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KAM329_005410	COG0762	integral membrane protein
KAM329_005420	COG1872	DUF167
KAM329_005460	COG3112	Uncharacterised protein family (UPF0231)
KAM329_005470	COG3835	regulator
KAM329_005480	COG2610	gluconate transmembrane transporter activity
KAM329_005490	COG1929	Belongs to the glycerate kinase type-1 family
KAM329_005520	COG0583	DNA-binding transcription factor activity
KAM329_005530	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KAM329_005560	COG0347	Belongs to the P(II) protein family
KAM329_005590	COG3842	ATPase activity
KAM329_005600	COG2837	iron assimilation
KAM329_005610	COG1438	arginine binding
KAM329_005620	COG1126	abc transporter atp-binding protein
KAM329_005630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM329_005640	COG4215	(ABC) transporter
KAM329_005650	COG4160	amino acid transport
KAM329_005660	COG0039	L-malate dehydrogenase activity
KAM329_005680	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
KAM329_005690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KAM329_005690	COG1017	nitric oxide dioxygenase activity
KAM329_005710	COG4536	flavin adenine dinucleotide binding
KAM329_005720	COG4137	Cytochrome C assembly protein
KAM329_005730	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KAM329_005740	COG0228	four-way junction DNA binding
KAM329_005750	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KAM329_005760	COG0336	Belongs to the RNA methyltransferase TrmD family
KAM329_005770	COG0335	large ribosomal subunit rRNA binding
KAM329_005800	COG1051	belongs to the nudix hydrolase family
KAM329_005820	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KAM329_005830	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KAM329_005840	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KAM329_005860	COG0583	DNA-binding transcription factor activity
KAM329_005870	COG0640	Transcriptional regulator
KAM329_005880	COG0268	Binds directly to 16S ribosomal RNA
KAM329_005890	COG0728	peptidoglycan biosynthetic process
KAM329_005900	COG0196	riboflavin kinase activity
KAM329_005910	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KAM329_005920	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KAM329_005930	COG1047	Peptidyl-prolyl cis-trans
KAM329_005940	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KAM329_006000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KAM329_006000	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KAM329_006030	COG1854	S-ribosylhomocysteine lyase activity
KAM329_006040	COG3706	GGDEF domain
KAM329_006050	COG0557	exoribonuclease II activity
KAM329_006060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KAM329_006080	COG2153	protein acetylation
KAM329_006100	COG1914	H( )-stimulated, divalent metal cation uptake system
KAM329_006110	COG0360	Binds together with S18 to 16S ribosomal RNA
KAM329_006120	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KAM329_006130	COG0359	binds to the 23S rRNA
KAM329_006210	COG1238	metal cluster binding
KAM329_006220	COG0612	Peptidase, M16
KAM329_006230	COG2918	glutathione biosynthetic process
KAM329_006240	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KAM329_006250	COG1027	Aspartate ammonia-lyase
KAM329_006260	COG3030	protein affecting phage T7 exclusion by the F plasmid
KAM329_006270	COG0534	Mate efflux family protein
KAM329_006290	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KAM329_006300	COG0459	protein refolding
KAM329_006340	COG0564	pseudouridine synthase activity
KAM329_006350	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KAM329_006360	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KAM329_006390	COG3335	DDE superfamily endonuclease
KAM329_006400	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KAM329_006410	COG4208	sulfate ABC transporter
KAM329_006420	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KAM329_006430	COG0583	DNA-binding transcription factor activity
KAM329_006440	COG3397	chitin binding
KAM329_006450	COG0840	transmembrane signaling receptor activity
KAM329_006500	COG1328	CTP reductase activity
KAM329_006510	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KAM329_006540	COG1448	Aminotransferase
KAM329_006550	COG2194	sulfuric ester hydrolase activity
KAM329_006590	COG1215	transferase activity, transferring glycosyl groups
KAM329_006600	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KAM329_006610	COG0457	Tetratricopeptide repeat
KAM329_006610	COG3118	belongs to the thioredoxin family
KAM329_006680	COG0513	Belongs to the DEAD box helicase family
KAM329_006690	COG0840	transmembrane signaling receptor activity
KAM329_006710	COG4166	transmembrane transport
KAM329_006740	COG1024	Enoyl-CoA hydratase
KAM329_006770	COG4221	oxidoreductase activity
KAM329_006780	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KAM329_006790	COG0442	prolyl-tRNA aminoacylation
KAM329_006800	COG0840	transmembrane signaling receptor activity
KAM329_006810	COG0632	four-way junction helicase activity
KAM329_006820	COG2255	four-way junction helicase activity
KAM329_006830	COG1271	oxidase subunit
KAM329_006840	COG1294	oxidase, subunit
KAM329_006850	COG3790	cyd operon protein YbgE
KAM329_006860	COG0824	Thioesterase
KAM329_006870	COG0811	peptide transport
KAM329_006900	COG0823	Involved in the tonB-independent uptake of proteins
KAM329_006910	COG2885	chlorophyll binding
KAM329_006920	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
KAM329_006930	COG0840	transmembrane signaling receptor activity
KAM329_006940	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KAM329_006960	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KAM329_006970	COG1640	4-alpha-glucanotransferase
KAM329_006980	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KAM329_007040	COG2130	NADP-dependent
KAM329_007050	COG1846	Transcriptional regulator
KAM329_007110	COG0561	phosphatase activity
KAM329_007140	COG0733	neurotransmitter:sodium symporter activity
KAM329_007150	COG0733	neurotransmitter:sodium symporter activity
KAM329_007180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KAM329_007210	COG1794	racemase activity, acting on amino acids and derivatives
KAM329_007230	COG1022	Amp-dependent synthetase and ligase
KAM329_007250	COG0456	acetyltransferase
KAM329_007280	COG2425	protein containing a von Willebrand factor type A (vWA) domain
KAM329_007290	COG5001	Diguanylate cyclase
KAM329_007290	COG5002	protein histidine kinase activity
KAM329_007310	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KAM329_007330	COG0456	acetyltransferase
KAM329_007350	COG0456	acetyltransferase
KAM329_007360	COG1902	pentaerythritol trinitrate reductase activity
KAM329_007380	COG2852	Protein conserved in bacteria
KAM329_007400	COG2957	Belongs to the agmatine deiminase family
KAM329_007410	COG0154	amidase activity
KAM329_007480	COG2207	Transcriptional regulator
KAM329_007480	COG1917	Cupin 2, conserved barrel domain protein
KAM329_007500	COG0513	Belongs to the DEAD box helicase family
KAM329_007510	COG2203	Gaf domain
KAM329_007510	COG2199	diguanylate cyclase activity
KAM329_007590	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
KAM329_007610	COG0577	efflux transmembrane transporter activity
KAM329_007610	COG1136	(ABC) transporter
KAM329_007620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM329_007630	COG0745	RESPONSE REGULATOR receiver
KAM329_007640	COG2205	protein histidine kinase activity
KAM329_007700	COG1280	lysine exporter protein (LysE YggA)
KAM329_007710	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KAM329_007720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KAM329_007740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM329_007800	COG0745	RESPONSE REGULATOR receiver
KAM329_007810	COG3104	oligopeptide transport
KAM329_007820	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KAM329_007830	COG1555	photosystem II stabilization
KAM329_007850	COG3385	transposase activity
KAM329_007860	COG2350	Protein conserved in bacteria
KAM329_007870	COG2917	probably involved in intracellular septation
KAM329_007880	COG0076	glutamate decarboxylase activity
KAM329_007890	COG1272	protein, Hemolysin III
KAM329_007900	COG2985	domain, Protein
KAM329_007900	COG0569	domain protein
KAM329_007920	COG0477	Major facilitator Superfamily
KAM329_007930	COG0583	DNA-binding transcription factor activity
KAM329_007940	COG3227	Zinc metalloprotease (Elastase)
KAM329_007950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KAM329_007960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KAM329_007980	COG2731	YhcH YjgK YiaL family protein
KAM329_008000	COG0668	transmembrane transport
KAM329_008020	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KAM329_008040	COG0789	Transcriptional regulator
KAM329_008130	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KAM329_008150	COG0488	(ABC) transporter
KAM329_008160	COG0516	GMP reductase activity
KAM329_008160	COG0517	IMP dehydrogenase activity
KAM329_008180	COG0835	chemotaxis
KAM329_008180	COG0784	Response regulator, receiver
KAM329_008190	COG2755	lipolytic protein G-D-S-L family
KAM329_008200	COG4181	ATPase activity
KAM329_008210	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KAM329_008220	COG1090	epimerase
KAM329_008230	COG2200	EAL domain
KAM329_008240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KAM329_008250	COG4935	Belongs to the peptidase S8 family
KAM329_008250	COG2234	aminopeptidase activity
KAM329_008260	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KAM329_008270	COG3171	Protein conserved in bacteria
KAM329_008280	COG2066	Belongs to the glutaminase family
KAM329_008290	COG2897	thiosulfate sulfurtransferase activity
KAM329_008310	COG1132	(ABC) transporter
KAM329_008340	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
KAM329_008350	COG3300	MHYT domain
KAM329_008350	COG5001	Diguanylate cyclase
KAM329_008390	COG4628	conserved protein (DUF2132)
KAM329_008400	COG0688	phosphatidylethanolamine metabolic process
KAM329_008410	COG1162	GTPase activity
KAM329_008420	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KAM329_008430	COG3335	DDE superfamily endonuclease
KAM329_008450	COG1278	Cold shock
KAM329_008470	COG0840	transmembrane signaling receptor activity
KAM329_008480	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KAM329_008530	COG0848	biopolymer transport protein
KAM329_008540	COG0811	peptide transport
KAM329_008550	COG0811	peptide transport
KAM329_008570	COG4206	TonB-dependent receptor
KAM329_008580	COG4174	ABC transporter (Permease)
KAM329_008590	COG4239	(ABC) transporter, permease
KAM329_008610	COG0444	Belongs to the ABC transporter superfamily
KAM329_008620	COG4608	Belongs to the ABC transporter superfamily
KAM329_008640	COG2195	Cleaves the N-terminal amino acid of tripeptides
KAM329_008650	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
KAM329_008660	COG1073	alpha beta
KAM329_008690	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KAM329_008740	COG0243	molybdopterin cofactor binding
KAM329_008750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KAM329_008750	COG1648	precorrin-2 dehydrogenase activity
KAM329_008770	COG1116	anion transmembrane transporter activity
KAM329_008770	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KAM329_008780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KAM329_008790	COG1116	anion transmembrane transporter activity
KAM329_008800	COG2146	nitrite reductase [NAD(P)H] activity
KAM329_008800	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KAM329_008810	COG2146	nitrite reductase [NAD(P)H] activity
KAM329_008810	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KAM329_008820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM329_008830	COG2313	pseudouridylate synthase activity
KAM329_008870	COG0521	Mo-molybdopterin cofactor biosynthetic process
KAM329_008890	COG2966	Psort location CytoplasmicMembrane, score
KAM329_008920	COG4175	Glycine betaine
KAM329_008930	COG4176	ABC-type proline glycine betaine transport system permease component
KAM329_008940	COG2113	Glycine betaine
KAM329_008950	COG0175	sulfate reduction
KAM329_008960	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KAM329_008970	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KAM329_008990	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KAM329_009000	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KAM329_009020	COG0786	glutamate:sodium symporter activity
KAM329_009030	COG0252	asparaginase activity
KAM329_009040	COG3139	Protein of unknown function (DUF1315)
KAM329_009080	COG0616	signal peptide processing
KAM329_009090	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAM329_009090	COG1902	pentaerythritol trinitrate reductase activity
KAM329_009100	COG0778	Nitroreductase
KAM329_009120	COG0110	maltose O-acetyltransferase activity
KAM329_009130	COG2264	protein methyltransferase activity
KAM329_009140	COG0604	alcohol dehydrogenase
KAM329_009150	COG0583	DNA-binding transcription factor activity
KAM329_009160	COG2190	(PTS) system
KAM329_009160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM329_009160	COG1263	PTS System
KAM329_009170	COG4145	pantothenate transmembrane transporter activity
KAM329_009180	COG3924	membrane
KAM329_009190	COG0439	Biotin carboxylase
KAM329_009200	COG0511	ligase activity, forming carbon-carbon bonds
KAM329_009210	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KAM329_009220	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KAM329_009250	COG3381	protein complex oligomerization
KAM329_009270	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KAM329_009290	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KAM329_009300	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KAM329_009300	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KAM329_009330	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KAM329_009340	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KAM329_009350	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KAM329_009360	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KAM329_009390	COG0601	transmembrane transport
KAM329_009400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAM329_009410	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KAM329_009420	COG0142	geranyltranstransferase activity
KAM329_009430	COG1722	exodeoxyribonuclease VII activity
KAM329_009440	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KAM329_009450	COG1360	Flagellar Motor Protein
KAM329_009480	COG1534	Rna-binding protein
KAM329_009490	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KAM329_009510	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KAM329_009520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KAM329_009530	COG0149	triose-phosphate isomerase activity
KAM329_009540	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KAM329_009550	COG0779	Required for maturation of 30S ribosomal subunits
KAM329_009560	COG0195	Participates in both transcription termination and antitermination
KAM329_009570	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KAM329_009580	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KAM329_009590	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KAM329_009600	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KAM329_009610	COG1185	polyribonucleotide nucleotidyltransferase activity
KAM329_009620	COG2211	Major facilitator Superfamily
KAM329_009630	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KAM329_009640	COG1422	Protein of unknown function (DUF1090)
KAM329_009650	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KAM329_009660	COG0826	peptidase U32
KAM329_009700	COG0312	modulator of DNA gyrase
KAM329_009710	COG0312	modulator of DNA gyrase
KAM329_009730	COG4974	Belongs to the 'phage' integrase family
KAM329_009740	COG1970	mechanosensitive ion channel activity
KAM329_009770	COG0789	Transcriptional regulator
KAM329_009800	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM329_009820	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KAM329_009830	COG0321	lipoyl(octanoyl) transferase activity
KAM329_009840	COG2921	Belongs to the UPF0250 family
KAM329_009850	COG1686	Belongs to the peptidase S11 family
KAM329_009860	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KAM329_009870	COG2951	lytic endotransglycosylase activity
KAM329_009880	COG0772	Belongs to the SEDS family
KAM329_009890	COG0768	penicillin binding
KAM329_009900	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KAM329_009910	COG0799	negative regulation of ribosome biogenesis
KAM329_009920	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KAM329_009960	COG0495	leucyl-tRNA aminoacylation
KAM329_009970	COG2888	peptidyl-tyrosine sulfation
KAM329_009980	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KAM329_009990	COG4535	Mg2 and Co2 transporter CorC
KAM329_010000	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KAM329_010010	COG1702	phosphate starvation-inducible protein PhoH
KAM329_010020	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KAM329_010030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KAM329_010040	COG1335	isochorismatase
KAM329_010050	COG1278	Cold shock
KAM329_010080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAM329_010090	COG2199	diguanylate cyclase activity
KAM329_010110	COG2199	diguanylate cyclase activity
KAM329_010130	COG3385	transposase activity
KAM329_010140	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KAM329_010170	COG1464	Belongs to the NlpA lipoprotein family
KAM329_010180	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KAM329_010190	COG2011	ABC-type metal ion transport system permease component
KAM329_010200	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KAM329_010220	COG0516	GMP reductase activity
KAM329_010230	COG0189	ligase activity
KAM329_010230	COG4067	protein conserved in archaea
KAM329_010270	COG0300	oxidoreductase activity
KAM329_010310	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KAM329_010320	COG3214	Protein conserved in bacteria
KAM329_010350	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
KAM329_010360	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
KAM329_010370	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KAM329_010380	COG1053	succinate dehydrogenase
KAM329_010400	COG0584	glycerophosphoryl diester phosphodiesterase
KAM329_010410	COG3264	Mechanosensitive ion channel
KAM329_010410	COG1511	domain protein
KAM329_010430	COG0739	heme binding
KAM329_010460	COG0583	DNA-binding transcription factor activity
KAM329_010490	COG0583	DNA-binding transcription factor activity
KAM329_010500	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KAM329_010570	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KAM329_010580	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KAM329_010600	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KAM329_010610	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KAM329_010620	COG0546	phosphoglycolate phosphatase activity
KAM329_010630	COG0180	Tryptophanyl-tRNA synthetase
KAM329_010660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KAM329_010680	COG1012	belongs to the aldehyde dehydrogenase family
KAM329_010700	COG3385	transposase activity
KAM329_010710	COG2801	Transposase and inactivated derivatives
KAM329_010720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAM329_010750	COG0657	acetylesterase activity
KAM329_010770	COG0490	domain, Protein
KAM329_010770	COG0471	metal ion transport
KAM329_010780	COG0012	GTP binding
KAM329_010790	COG0193	aminoacyl-tRNA hydrolase activity
KAM329_010800	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KAM329_010810	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KAM329_010820	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KAM329_010830	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KAM329_010840	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KAM329_010850	COG2890	protein-(glutamine-N5) methyltransferase activity
KAM329_010870	COG2912	Transglutaminase-like superfamily
KAM329_010880	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KAM329_010890	COG1301	dicarboxylic acid transport
KAM329_010910	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KAM329_010940	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KAM329_010950	COG1115	amino acid carrier protein
KAM329_010990	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KAM329_011010	COG0189	ligase activity
KAM329_011020	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KAM329_011040	COG3091	SprT-like family
KAM329_011060	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KAM329_011080	COG2801	Transposase and inactivated derivatives
KAM329_011120	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KAM329_011130	COG0739	heme binding
KAM329_011140	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KAM329_011150	COG3408	Glycogen debranching enzyme
KAM329_011150	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
KAM329_011170	COG1881	PFAM PEBP family protein
KAM329_011180	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KAM329_011190	COG0583	DNA-binding transcription factor activity
KAM329_011210	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KAM329_011230	COG0583	DNA-binding transcription factor activity
KAM329_011240	COG1028	Short-chain dehydrogenase reductase Sdr
KAM329_011250	COG0616	signal peptide processing
KAM329_011260	COG3724	N-succinylarginine dihydrolase activity
KAM329_011300	COG0840	transmembrane signaling receptor activity
KAM329_011330	COG2971	BadF BadG BcrA BcrD
KAM329_011350	COG4608	Belongs to the ABC transporter superfamily
KAM329_011360	COG0444	Belongs to the ABC transporter superfamily
KAM329_011370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAM329_011400	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KAM329_011410	COG3039	Transposase
KAM329_011460	COG3328	transposase activity
KAM329_011480	COG2801	Transposase and inactivated derivatives
KAM329_011500	COG3039	Transposase
KAM329_011550	COG3039	Transposase
KAM329_011570	COG2801	Transposase and inactivated derivatives
KAM329_011610	COG0640	Transcriptional regulator
KAM329_011620	COG0798	PFAM Bile acid sodium symporter
KAM329_011630	COG1393	Belongs to the ArsC family
KAM329_011660	COG1677	Flagellar hook-basal body complex protein FliE
KAM329_011680	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KAM329_011790	COG1684	flagellar biosynthetic protein fliR
KAM329_011810	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KAM329_011860	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KAM329_011870	COG0784	Response regulator, receiver
KAM329_011870	COG0643	Histidine kinase
KAM329_011870	COG2198	Histidine kinase
KAM329_011890	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KAM329_011900	COG1360	Flagellar Motor Protein
KAM329_011910	COG1192	Involved in chromosome partitioning
KAM329_011930	COG0835	chemotaxis
KAM329_011960	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KAM329_011970	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KAM329_011980	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KAM329_011990	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KAM329_012000	COG1138	Cytochrome C-type biogenesis protein
KAM329_012010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KAM329_012030	COG0457	Tetratricopeptide repeat
KAM329_012060	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KAM329_012070	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KAM329_012070	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KAM329_012100	COG0259	pyridoxamine-phosphate oxidase activity
KAM329_012160	COG3153	acetyltransferase
KAM329_012190	COG0800	Aldolase
KAM329_012200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM329_012220	COG2721	sulfolactate sulfo-lyase activity
KAM329_012230	COG0246	Mannitol dehydrogenase
KAM329_012290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KAM329_012350	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KAM329_012370	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KAM329_012420	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KAM329_012430	COG2003	Belongs to the UPF0758 family
KAM329_012440	COG3039	Transposase
KAM329_012480	COG3039	Transposase
KAM329_012490	COG2850	peptidyl-arginine hydroxylation
KAM329_012510	COG4122	O-methyltransferase activity
KAM329_012540	COG0210	DNA helicase
KAM329_012540	COG0210	DNA helicase
KAM329_012610	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KAM329_012620	COG2867	negative regulation of translational initiation
KAM329_012630	COG2914	Belongs to the UPF0125 (RnfH) family
KAM329_012640	COG0702	epimerase
KAM329_012650	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAM329_012660	COG1454	alcohol dehydrogenase
KAM329_012680	COG0564	pseudouridine synthase activity
KAM329_012690	COG1957	nucleoside hydrolase
KAM329_012750	COG1280	lysine exporter protein (LysE YggA)
KAM329_012770	COG3263	regulation of cellular component size
KAM329_012790	COG1876	peptidase activity
KAM329_012800	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KAM329_012810	COG1393	Belongs to the ArsC family
KAM329_012820	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM329_012850	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM329_012910	COG5433	transposase activity
KAM329_012920	COG3069	C4-dicarboxylate transmembrane transporter activity
KAM329_012930	COG1473	amidohydrolase
KAM329_012950	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KAM329_012960	COG0017	Asparaginyl-tRNA synthetase
KAM329_013000	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KAM329_013010	COG0156	8-amino-7-oxononanoate synthase activity
KAM329_013020	COG2226	methyltransferase
KAM329_013020	COG1073	alpha beta
KAM329_013030	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KAM329_013040	COG0501	Belongs to the peptidase M48B family
KAM329_013050	COG3217	Mosc domain protein beta barrel domain protein
KAM329_013050	COG0633	Ferredoxin
KAM329_013050	COG0633	Ferredoxin
KAM329_013050	COG3217	Mosc domain protein beta barrel domain protein
KAM329_013070	COG0674	pyruvate-flavodoxin oxidoreductase activity
KAM329_013070	COG1013	pyruvate-flavodoxin oxidoreductase activity
KAM329_013070	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KAM329_013070	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KAM329_013080	COG2841	Protein conserved in bacteria
KAM329_013100	COG0534	Mate efflux family protein
KAM329_013170	COG1309	transcriptional regulator
KAM329_013200	COG0791	NLP P60 protein
KAM329_013210	COG0583	DNA-binding transcription factor activity
KAM329_013250	COG0500	methyltransferase
KAM329_013260	COG4106	trans-aconitate 2-methyltransferase activity
KAM329_013270	COG1801	Protein of unknown function DUF72
KAM329_013280	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KAM329_013290	COG0217	transcriptional regulatory protein
KAM329_013300	COG2194	sulfuric ester hydrolase activity
KAM329_013320	COG1940	carbohydrate kinase activity
KAM329_013320	COG1846	Transcriptional regulator
KAM329_013330	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KAM329_013340	COG0363	glucosamine-6-phosphate deaminase activity
KAM329_013350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM329_013350	COG1263	PTS System
KAM329_013350	COG2190	(PTS) system
KAM329_013370	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KAM329_013380	COG0735	belongs to the Fur family
KAM329_013400	COG0716	FMN binding
KAM329_013430	COG0596	Alpha beta hydrolase
KAM329_013440	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
KAM329_013450	COG0033	Phosphoglucomutase
KAM329_013470	COG1846	Transcriptional regulator
KAM329_013480	COG2951	lytic endotransglycosylase activity
KAM329_013490	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KAM329_013500	COG4136	ATPase activity
KAM329_013520	COG4134	Bacterial extracellular solute-binding protein
KAM329_013530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KAM329_013540	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KAM329_013560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KAM329_013580	COG0729	surface antigen
KAM329_013590	COG2911	Protein conserved in bacteria
KAM329_013610	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KAM329_013630	COG0741	lytic transglycosylase activity
KAM329_013660	COG1607	acyl-coa hydrolase
KAM329_013760	COG3451	type IV secretory pathway VirB4
KAM329_013780	COG3838	Conjugal transfer protein Trbc
KAM329_013790	COG4962	Type ii secretion system protein e
KAM329_013830	COG0583	DNA-binding transcription factor activity
KAM329_013880	COG2076	Multidrug Resistance protein
KAM329_013920	COG4959	Type IV secretory pathway protease TraF
KAM329_013950	COG1192	Involved in chromosome partitioning
KAM329_014020	COG5489	Protein of unknown function (DUF736)
KAM329_014080	COG2003	Belongs to the UPF0758 family
KAM329_014100	COG4804	nuclease activity
KAM329_014120	COG0741	lytic transglycosylase activity
KAM329_014120	COG1388	LysM domain
KAM329_014130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KAM329_014140	COG2226	methyltransferase
KAM329_014150	COG0328	RNA-DNA hybrid ribonuclease activity
KAM329_014160	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KAM329_014180	COG0784	Response regulator, receiver
KAM329_014180	COG3437	response regulator, receiver
KAM329_014190	COG1960	acyl-CoA dehydrogenase activity
KAM329_014200	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KAM329_014210	COG0121	glutamine amidotransferase
KAM329_014230	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KAM329_014290	COG2197	response regulator
KAM329_014300	COG3850	Histidine kinase
KAM329_014310	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KAM329_014320	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
KAM329_014320	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KAM329_014340	COG0243	molybdopterin cofactor binding
KAM329_014350	COG0437	4 iron, 4 sulfur cluster binding
KAM329_014360	COG0348	domain, Protein
KAM329_014380	COG3005	denitrification pathway
KAM329_014390	COG0521	Mo-molybdopterin cofactor biosynthetic process
KAM329_014400	COG0315	cyclic pyranopterin monophosphate synthase activity
KAM329_014410	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KAM329_014420	COG0314	molybdopterin synthase activity
KAM329_014450	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KAM329_014470	COG3335	DDE superfamily endonuclease
KAM329_014510	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KAM329_014530	COG0302	gtp cyclohydrolase
KAM329_014540	COG0840	transmembrane signaling receptor activity
KAM329_014550	COG0840	transmembrane signaling receptor activity
KAM329_014560	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KAM329_014580	COG0583	DNA-binding transcription factor activity
KAM329_014600	COG3335	DDE superfamily endonuclease
KAM329_014630	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KAM329_014660	COG2195	Cleaves the N-terminal amino acid of tripeptides
KAM329_014670	COG1166	arginine decarboxylase activity
KAM329_014720	COG1403	HNH endonuclease
KAM329_014730	COG5433	transposase activity
KAM329_014770	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KAM329_014780	COG1187	pseudouridine synthase activity
KAM329_014790	COG2807	transmembrane transport
KAM329_014810	COG0583	DNA-binding transcription factor activity
KAM329_014850	COG2979	Protein of unknown function (DUF533)
KAM329_014870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KAM329_014880	COG1271	oxidase subunit
KAM329_014890	COG1294	oxidase, subunit
KAM329_014900	COG2814	Major facilitator Superfamily
KAM329_014910	COG0656	L-ascorbic acid biosynthetic process
KAM329_014950	COG0583	DNA-binding transcription factor activity
KAM329_014960	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KAM329_014970	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KAM329_014980	COG2271	Major facilitator Superfamily
KAM329_015000	COG2271	Major facilitator Superfamily
KAM329_015010	COG1349	DNA-binding transcription factor activity
KAM329_015030	COG0584	glycerophosphoryl diester phosphodiesterase
KAM329_015040	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAM329_015050	COG0287	Prephenate dehydrogenase
KAM329_015050	COG1605	Chorismate mutase
KAM329_015070	COG3085	chromosome segregation
KAM329_015080	COG4574	serine-type endopeptidase inhibitor activity
KAM329_015110	COG0675	Transposase, IS605 OrfB family
KAM329_015130	COG4771	TonB-dependent receptor
KAM329_015140	COG3083	sulfuric ester hydrolase activity
KAM329_015150	COG3082	Protein of unknown function (DUF1414)
KAM329_015160	COG3081	Nucleoid-associated protein
KAM329_015180	COG1175	transmembrane transport
KAM329_015190	COG3833	ABC-type maltose transport systems, permease component
KAM329_015200	COG3842	ATPase activity
KAM329_015220	COG0596	Alpha beta hydrolase
KAM329_015250	COG0425	Belongs to the sulfur carrier protein TusA family
KAM329_015260	COG4783	chaperone-mediated protein folding
KAM329_015280	COG1393	Belongs to the ArsC family
KAM329_015320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM329_015330	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KAM329_015340	COG2431	L-lysine efflux transmembrane transporter activity
KAM329_015360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM329_015380	COG4160	amino acid transport
KAM329_015400	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KAM329_015420	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAM329_015470	COG0628	permease
KAM329_015480	COG2373	Large extracellular alpha-helical protein
KAM329_015490	COG4953	penicillin-binding protein 1C
KAM329_015510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KAM329_015510	COG0301	tRNA thio-modification
KAM329_015630	COG2089	acid synthase
KAM329_015650	COG1083	cytidylyl-transferase
KAM329_015680	COG1028	Short-chain dehydrogenase reductase Sdr
KAM329_015690	COG0318	PFAM AMP-dependent synthetase and ligase
KAM329_015720	COG1215	transferase activity, transferring glycosyl groups
KAM329_015730	COG0562	UDP-galactopyranose mutase
KAM329_015750	COG1216	Glycosyl transferase, family 2
KAM329_015810	COG2226	methyltransferase
KAM329_015820	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KAM329_015830	COG1086	Polysaccharide biosynthesis protein
KAM329_015850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KAM329_015870	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KAM329_015900	COG0346	lactoylglutathione lyase activity
KAM329_015910	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KAM329_015920	COG4660	Part of a membrane complex involved in electron transport
KAM329_015930	COG4659	FMN binding
KAM329_015940	COG4658	electron transport chain
KAM329_015960	COG4656	Part of a membrane complex involved in electron transport
KAM329_015970	COG2878	Part of a membrane complex involved in electron transport
KAM329_015980	COG4657	Part of a membrane complex involved in electron transport
KAM329_015990	COG0675	Transposase, IS605 OrfB family
KAM329_016010	COG0697	spore germination
KAM329_016040	COG3039	Transposase
KAM329_016050	COG1484	DNA-dependent DNA replication
KAM329_016060	COG4584	PFAM Integrase catalytic
KAM329_016090	COG3335	DDE superfamily endonuclease
KAM329_016140	COG5433	transposase activity
KAM329_016200	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KAM329_016220	COG1288	antiporter activity
KAM329_016230	COG0436	Aminotransferase
KAM329_016250	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KAM329_016260	COG2027	D-alanyl-D-alanine carboxypeptidase
KAM329_016270	COG1061	Type III restriction enzyme res subunit
KAM329_016280	COG1566	PFAM secretion protein HlyD family protein
KAM329_016310	COG0675	Transposase, IS605 OrfB family
KAM329_016320	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KAM329_016320	COG3264	Mechanosensitive ion channel
KAM329_016330	COG1966	Carbon starvation protein
KAM329_016340	COG3279	Response regulator of the LytR AlgR family
KAM329_016350	COG3275	phosphorelay sensor kinase activity
KAM329_016370	COG1012	belongs to the aldehyde dehydrogenase family
KAM329_016370	COG1454	alcohol dehydrogenase
KAM329_016380	COG2095	MarC family integral membrane protein
KAM329_016400	COG0601	transmembrane transport
KAM329_016410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAM329_016420	COG0444	Belongs to the ABC transporter superfamily
KAM329_016440	COG0861	Integral membrane protein TerC family
KAM329_016450	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KAM329_016470	COG1301	dicarboxylic acid transport
KAM329_016500	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KAM329_016530	COG0537	adenosine 5'-monophosphoramidase activity
KAM329_016600	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAM329_016610	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAM329_016640	COG2354	Protein conserved in bacteria
KAM329_016650	COG1164	Oligoendopeptidase f
KAM329_016660	COG1164	Oligoendopeptidase f
KAM329_016670	COG3150	esterase
KAM329_016680	COG1252	NADH dehydrogenase
KAM329_016690	COG0393	Putative heavy-metal-binding
KAM329_016700	COG1368	sulfuric ester hydrolase activity
KAM329_016720	COG0527	aspartate kinase activity
KAM329_016740	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KAM329_016740	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KAM329_016750	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KAM329_016800	COG0583	DNA-binding transcription factor activity
KAM329_016810	COG1620	l-lactate permease
KAM329_016820	COG0247	lactate metabolic process
KAM329_016830	COG1139	Iron-sulfur cluster binding protein
KAM329_016870	COG0577	efflux transmembrane transporter activity
KAM329_016880	COG1136	(ABC) transporter
KAM329_016920	COG2814	Major facilitator Superfamily
KAM329_016970	COG0672	)-iron permease
KAM329_017040	COG2308	Evidence 4 Homologs of previously reported genes of
KAM329_017060	COG0300	oxidoreductase activity
KAM329_017090	COG0659	secondary active sulfate transmembrane transporter activity
KAM329_017120	COG2003	Belongs to the UPF0758 family
KAM329_017170	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KAM329_017180	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KAM329_017200	COG0326	Molecular chaperone. Has ATPase activity
KAM329_017210	COG0563	adenylate kinase activity
KAM329_017220	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KAM329_017230	COG3788	relative of glutathione S-transferase, MAPEG superfamily
KAM329_017240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM329_017250	COG0840	transmembrane signaling receptor activity
KAM329_017270	COG0675	Transposase, IS605 OrfB family
KAM329_017310	COG3300	MHYT domain
KAM329_017310	COG5001	Diguanylate cyclase
KAM329_017360	COG1021	2,3-dihydroxybenzoate-AMP ligase
KAM329_017370	COG3433	isochorismatase activity
KAM329_017370	COG1535	isochorismatase
KAM329_017380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KAM329_017390	COG1028	Short-chain dehydrogenase reductase Sdr
KAM329_017420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KAM329_017460	COG1120	ATPase activity
KAM329_017470	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAM329_017480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAM329_017490	COG4771	TonB-dependent receptor
KAM329_017570	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KAM329_017580	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KAM329_017590	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAM329_017600	COG0861	Integral membrane protein TerC family
KAM329_017630	COG1022	Amp-dependent synthetase and ligase
KAM329_017640	COG0295	cytidine deaminase activity
KAM329_017650	COG1346	cytolysis
KAM329_017660	COG1380	Effector of murein hydrolase LrgA
KAM329_017670	COG3345	alpha-galactosidase
KAM329_017690	COG2925	Exonuclease
KAM329_017710	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KAM329_017720	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KAM329_017720	COG0392	lysyltransferase activity
KAM329_017750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KAM329_017760	COG0436	Aminotransferase
KAM329_017770	COG0583	DNA-binding transcription factor activity
KAM329_017780	COG2160	L-arabinose isomerase activity
KAM329_017800	COG1069	ribulokinase activity
KAM329_017810	COG1879	ABC-type sugar transport system periplasmic component
KAM329_017820	COG1129	ABC transporter
KAM329_017830	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAM329_017850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KAM329_017860	COG0254	rRNA binding
KAM329_017890	COG1451	nucleotide metabolic process
KAM329_017930	COG3069	C4-dicarboxylate transmembrane transporter activity
KAM329_017950	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KAM329_017950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAM329_017960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KAM329_018000	COG2009	succinate dehydrogenase
KAM329_018010	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KAM329_018040	COG0567	Dehydrogenase, E1 component
KAM329_018050	COG0508	dehydrogenase complex catalyzes the overall conversion of
KAM329_018060	COG0045	succinate-CoA ligase (ADP-forming) activity
KAM329_018070	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KAM329_018080	COG2801	Transposase and inactivated derivatives
KAM329_018120	COG2983	Belongs to the UPF0260 family
KAM329_018130	COG1882	Formate acetyltransferase
KAM329_018140	COG2116	formate transmembrane transporter activity
KAM329_018150	COG1944	ATP diphosphatase activity
KAM329_018170	COG2076	Multidrug Resistance protein
KAM329_018180	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KAM329_018190	COG1278	Cold shock
KAM329_018200	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KAM329_018210	COG0542	response to heat
KAM329_018220	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KAM329_018230	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KAM329_018240	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KAM329_018250	COG3134	Outer membrane lipoprotein
KAM329_018260	COG3706	GGDEF domain
KAM329_018270	COG0492	ferredoxin-NADP+ reductase activity
KAM329_018280	COG0686	Belongs to the AlaDH PNT family
KAM329_018300	COG1674	ftsk spoiiie
KAM329_018300	COG0531	amino acid
KAM329_018310	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KAM329_018320	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KAM329_018330	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KAM329_018340	COG1286	toxin biosynthetic process
KAM329_018350	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KAM329_018360	COG2723	6-phospho-beta-galactosidase activity
KAM329_018370	COG1263	PTS System
KAM329_018370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM329_018380	COG1609	Transcriptional regulator
KAM329_018400	COG4172	Belongs to the ABC transporter superfamily
KAM329_018420	COG4171	peptide transport system, permease
KAM329_018450	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KAM329_018460	COG1842	Phage shock protein A
KAM329_018490	COG3106	COG3106 Predicted ATPase
KAM329_018500	COG3768	UPF0283 membrane protein
KAM329_018520	COG2154	pterin-4-alpha-carbinolamine dehydratase
KAM329_018570	COG2885	chlorophyll binding
KAM329_018580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KAM329_018600	COG1570	exodeoxyribonuclease VII activity
KAM329_018700	COG3415	Transposase
KAM329_018700	COG2801	Transposase and inactivated derivatives
KAM329_018730	COG3220	belongs to the UPF0276 family
KAM329_018770	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KAM329_018780	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
KAM329_018800	COG1595	DNA-templated transcription, initiation
KAM329_018820	COG3039	Transposase
KAM329_018830	COG0366	Alpha amylase catalytic
KAM329_018830	COG1874	Beta-galactosidase
KAM329_018860	COG0516	GMP reductase activity
KAM329_018860	COG0517	IMP dehydrogenase activity
KAM329_018870	COG0519	Catalyzes the synthesis of GMP from XMP
KAM329_018870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KAM329_018920	COG1846	Transcriptional regulator
KAM329_018940	COG0500	methyltransferase
KAM329_018960	COG2062	phosphohistidine phosphatase, SixA
KAM329_018980	COG0697	spore germination
KAM329_019000	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
KAM329_019020	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KAM329_019040	COG4591	ABC-type transport system involved in lipoprotein release permease component
KAM329_019050	COG1136	(ABC) transporter
KAM329_019060	COG4591	ABC-type transport system involved in lipoprotein release permease component
KAM329_019070	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KAM329_019100	COG0544	peptidyl-prolyl cis-trans isomerase activity
KAM329_019110	COG0740	serine-type endopeptidase activity
KAM329_019120	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KAM329_019130	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KAM329_019140	COG0776	regulation of translation
KAM329_019150	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KAM329_019160	COG0488	(ABC) transporter
KAM329_019170	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KAM329_019180	COG3162	membrane
KAM329_019210	COG1024	Enoyl-CoA hydratase
KAM329_019220	COG1115	amino acid carrier protein
KAM329_019240	COG3228	Belongs to the MtfA family
KAM329_019250	COG1584	GPR1 FUN34 yaaH family protein
KAM329_019300	COG1024	Enoyl-CoA hydratase
KAM329_019310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KAM329_019320	COG1960	acyl-CoA dehydrogenase activity
KAM329_019340	COG1960	acyl-CoA dehydrogenase activity
KAM329_019350	COG1024	Enoyl-CoA hydratase
KAM329_019360	COG1024	Enoyl-CoA hydratase
KAM329_019380	COG1028	Short-chain dehydrogenase reductase Sdr
KAM329_019400	COG0730	response to heat
KAM329_019420	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAM329_019430	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAM329_019440	COG1129	ABC transporter
KAM329_019450	COG3385	transposase activity
KAM329_019460	COG1879	ABC-type sugar transport system periplasmic component
KAM329_019470	COG0583	DNA-binding transcription factor activity
KAM329_019500	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KAM329_019510	COG0243	molybdopterin cofactor binding
KAM329_019540	COG0583	DNA-binding transcription factor activity
KAM329_019550	COG2723	6-phospho-beta-galactosidase activity
KAM329_019570	COG0583	DNA-binding transcription factor activity
KAM329_019600	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KAM329_019610	COG0673	inositol 2-dehydrogenase activity
KAM329_019620	COG0583	DNA-binding transcription factor activity
KAM329_019640	COG1560	Kdo2-lipid A biosynthetic process
KAM329_019650	COG1560	Kdo2-lipid A biosynthetic process
KAM329_019680	COG0417	DNA replication proofreading
KAM329_019920	COG0625	glutathione transferase activity
KAM329_019930	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KAM329_019950	COG0583	DNA-binding transcription factor activity
KAM329_019980	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KAM329_020010	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KAM329_020050	COG1846	Transcriptional regulator
KAM329_020060	COG0583	DNA-binding transcription factor activity
KAM329_020080	COG2948	multi-organism process
KAM329_020280	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM329_020300	COG3385	transposase activity
KAM329_020320	COG3335	DDE superfamily endonuclease
KAM329_020350	COG5433	transposase activity
KAM329_020360	COG5433	transposase activity
KAM329_020370	COG3284	Transcriptional regulator
KAM329_020400	COG1461	Dihydroxyacetone kinase
KAM329_020410	COG2376	Dihydroxyacetone kinase
KAM329_020420	COG2252	PERMEase
KAM329_020480	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KAM329_020510	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KAM329_020540	COG5433	transposase activity
KAM329_020590	COG0534	Mate efflux family protein
KAM329_020610	COG0307	riboflavin synthase, alpha
KAM329_020640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAM329_020650	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KAM329_020660	COG0697	spore germination
KAM329_020670	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KAM329_020730	COG0675	Transposase, IS605 OrfB family
KAM329_020740	COG2996	Protein conserved in bacteria
KAM329_020770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KAM329_020780	COG3099	Belongs to the UPF0263 family
KAM329_020790	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KAM329_020800	COG2894	cell division
KAM329_020810	COG0850	regulation of cytokinetic process
KAM329_020820	COG3100	YcgL domain-containing protein
KAM329_020830	COG2951	lytic endotransglycosylase activity
KAM329_020840	COG1760	l-serine dehydratase
KAM329_020850	COG1760	l-serine dehydratase
KAM329_020860	COG3123	guanosine phosphorylase activity
KAM329_020870	COG1301	dicarboxylic acid transport
KAM329_020900	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KAM329_020910	COG2067	long-chain fatty acid transport protein
KAM329_020920	COG2067	long-chain fatty acid transport protein
KAM329_020940	COG1595	DNA-templated transcription, initiation
KAM329_020990	COG0714	Associated with various cellular activities
KAM329_021000	COG0183	Belongs to the thiolase family
KAM329_021010	COG1250	3-hydroxyacyl-CoA dehydrogenase
KAM329_021010	COG1024	Enoyl-CoA hydratase
KAM329_021030	COG4681	YaeQ
KAM329_021070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAM329_021100	COG3134	Outer membrane lipoprotein
KAM329_021120	COG0675	Transposase, IS605 OrfB family
KAM329_021130	COG0318	PFAM AMP-dependent synthetase and ligase
KAM329_021140	COG2378	regulation of single-species biofilm formation
KAM329_021160	COG0140	phosphoribosyl-ATP diphosphatase activity
KAM329_021160	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KAM329_021170	COG0107	imidazoleglycerol-phosphate synthase activity
KAM329_021180	COG2205	protein histidine kinase activity
KAM329_021180	COG0784	Response regulator, receiver
KAM329_021180	COG2198	Histidine kinase
KAM329_021190	COG2199	diguanylate cyclase activity
KAM329_021200	COG3437	response regulator, receiver
KAM329_021210	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KAM329_021220	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KAM329_021230	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KAM329_021230	COG0131	Imidazoleglycerol-phosphate dehydratase
KAM329_021240	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KAM329_021250	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KAM329_021260	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KAM329_021280	COG1199	ATP-dependent helicase activity
KAM329_021290	COG3385	transposase activity
KAM329_021300	COG1214	PFAM Peptidase M22, glycoprotease
KAM329_021320	COG0596	Alpha beta hydrolase
KAM329_021330	COG0318	PFAM AMP-dependent synthetase and ligase
KAM329_021360	COG0697	spore germination
KAM329_021380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KAM329_021390	COG2832	Protein of unknown function (DUF454)
KAM329_021400	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KAM329_021420	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KAM329_021430	COG0583	DNA-binding transcription factor activity
KAM329_021450	COG3314	Sporulation integral membrane protein YlbJ
KAM329_021530	COG2197	response regulator
KAM329_021540	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KAM329_021540	COG0517	IMP dehydrogenase activity
KAM329_021540	COG0617	tRNA 3'-terminal CCA addition
KAM329_021550	COG1643	Atp-dependent helicase
KAM329_021570	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KAM329_021600	COG0675	Transposase, IS605 OrfB family
KAM329_021610	COG0784	Response regulator, receiver
KAM329_021610	COG5002	protein histidine kinase activity
KAM329_021610	COG2205	protein histidine kinase activity
KAM329_021660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KAM329_021670	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
KAM329_021680	COG0709	Synthesizes selenophosphate from selenide and ATP
KAM329_021710	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KAM329_021720	COG0840	transmembrane signaling receptor activity
KAM329_021730	COG1254	Belongs to the acylphosphatase family
KAM329_021750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM329_021750	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM329_021760	COG0489	protein tyrosine kinase activity
KAM329_021770	COG0572	uridine kinase
KAM329_021780	COG0717	Belongs to the dCTP deaminase family
KAM329_021790	COG0306	phosphate transporter
KAM329_021800	COG1530	ribonuclease E activity
KAM329_021810	COG0564	pseudouridine synthase activity
KAM329_021840	COG1399	metal-binding, possibly nucleic acid-binding protein
KAM329_021850	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KAM329_021860	COG0416	fatty acid biosynthetic process
KAM329_021870	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KAM329_021890	COG1028	Short-chain dehydrogenase reductase Sdr
KAM329_021900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KAM329_021910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KAM329_021920	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KAM329_021930	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KAM329_021940	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KAM329_021950	COG0470	DNA polymerase III
KAM329_021960	COG0084	hydrolase, TatD family'
KAM329_021990	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
KAM329_021990	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KAM329_022000	COG3008	intermembrane lipid transfer
KAM329_022010	COG2995	paraquat-inducible protein a
KAM329_022030	COG3141	response to X-ray
KAM329_022080	COG3039	Transposase
KAM329_022180	COG5642	Protein of unknown function (DUF2384)
KAM329_022200	COG3328	transposase activity
KAM329_022210	COG3385	transposase activity
KAM329_022270	COG3039	Transposase
KAM329_022290	COG5499	transcription regulator containing HTH domain
KAM329_022300	COG1067	ATP-dependent peptidase activity
KAM329_022310	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KAM329_022340	COG0488	(ABC) transporter
KAM329_022360	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KAM329_022360	COG0116	Belongs to the methyltransferase superfamily
KAM329_022380	COG0167	dihydroorotate dehydrogenase activity
KAM329_022390	COG2902	Dehydrogenase
KAM329_022410	COG0308	aminopeptidase N
KAM329_022430	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
KAM329_022440	COG1956	GAF domain-containing protein
KAM329_022460	COG3278	Belongs to the heme-copper respiratory oxidase family
KAM329_022490	COG2010	Cytochrome c
KAM329_022510	COG2217	Heavy metal translocating P-type atpase
KAM329_022540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KAM329_022550	COG0589	response to stress
KAM329_022560	COG0037	tRNA processing
KAM329_022590	COG0625	glutathione transferase activity
KAM329_022600	COG1869	D-ribose catabolic process
KAM329_022610	COG1129	ABC transporter
KAM329_022620	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAM329_022630	COG1879	ABC-type sugar transport system periplasmic component
KAM329_022640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM329_022650	COG1609	Transcriptional regulator
KAM329_022680	COG5001	Diguanylate cyclase
KAM329_022680	COG3300	MHYT domain
KAM329_022750	COG0776	regulation of translation
KAM329_022760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM329_022760	COG0072	phenylalanine-tRNA ligase activity
KAM329_022770	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KAM329_022780	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KAM329_022790	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KAM329_022800	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KAM329_022810	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KAM329_022910	COG0675	Transposase, IS605 OrfB family
KAM329_022950	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KAM329_022970	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KAM329_022980	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KAM329_022990	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KAM329_023000	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
KAM329_023010	COG3313	Fe-S protein
KAM329_023020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KAM329_023020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KAM329_023020	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KAM329_023030	COG1105	Belongs to the carbohydrate kinase PfkB family
KAM329_023040	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM329_023040	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM329_023050	COG1609	Transcriptional regulator
KAM329_023060	COG0814	amino acid
KAM329_023090	COG0513	Belongs to the DEAD box helicase family
KAM329_023110	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KAM329_023120	COG2890	protein-(glutamine-N5) methyltransferase activity
KAM329_023130	COG2840	Smr protein MutS2
KAM329_023200	COG2824	Alkylphosphonate utilization operon protein PhnA
KAM329_023230	COG1280	lysine exporter protein (LysE YggA)
KAM329_023260	COG0675	Transposase, IS605 OrfB family
KAM329_023340	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KAM329_023350	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
KAM329_023370	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KAM329_023380	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KAM329_023400	COG0205	6-phosphofructokinase activity
KAM329_023410	COG1473	amidohydrolase
KAM329_023420	COG1011	Hydrolase
KAM329_023430	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KAM329_023450	COG3593	DNA synthesis involved in DNA repair
KAM329_023480	COG0583	DNA-binding transcription factor activity
KAM329_023490	COG0730	response to heat
KAM329_023500	COG3148	PFAM DTW domain containing protein
KAM329_023510	COG1181	Belongs to the D-alanine--D-alanine ligase family
KAM329_023530	COG0386	Belongs to the glutathione peroxidase family
KAM329_023540	COG0513	Belongs to the DEAD box helicase family
KAM329_023570	COG1742	UPF0060 membrane protein
KAM329_023620	COG2329	Antibiotic biosynthesis monooxygenase
KAM329_023630	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KAM329_023670	COG3243	poly(R)-hydroxyalkanoic acid synthase
KAM329_023690	COG2501	S4 domain
KAM329_023720	COG1132	(ABC) transporter
KAM329_023730	COG1132	(ABC) transporter
KAM329_023750	COG3118	belongs to the thioredoxin family
KAM329_023760	COG3118	belongs to the thioredoxin family
KAM329_023770	COG0471	metal ion transport
KAM329_023790	COG0058	SHG alpha-glucan phosphorylase activity
KAM329_023850	COG0814	amino acid
KAM329_023860	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KAM329_023870	COG0514	ATP-dependent DNA helicase (RecQ)
KAM329_023880	COG2766	serine protein kinase
KAM329_023890	COG2718	Belongs to the UPF0229 family
KAM329_023900	COG2719	SpoVR family
KAM329_023910	COG2186	Transcriptional regulator
KAM329_023920	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KAM329_023930	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KAM329_023940	COG0586	Pfam SNARE associated Golgi protein
KAM329_023960	COG0556	nucleotide-excision repair
KAM329_023970	COG2985	domain, Protein
KAM329_023970	COG0569	domain protein
KAM329_024000	COG1196	nuclear chromosome segregation
KAM329_024000	COG0741	lytic transglycosylase activity
KAM329_024000	COG0739	heme binding
KAM329_024010	COG0675	Transposase, IS605 OrfB family
KAM329_024060	COG4565	transcriptional regulatory protein
KAM329_024070	COG3290	protein histidine kinase activity
KAM329_024080	COG1940	carbohydrate kinase activity
KAM329_024080	COG1846	Transcriptional regulator
KAM329_024090	COG0840	transmembrane signaling receptor activity
KAM329_024110	COG3012	SEC-C Motif Domain Protein
KAM329_024120	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KAM329_024130	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KAM329_024140	COG0247	lactate metabolic process
KAM329_024160	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
KAM329_024170	COG0437	4 iron, 4 sulfur cluster binding
KAM329_024180	COG3301	Polysulphide reductase, NrfD
KAM329_024190	COG1138	Cytochrome C-type biogenesis protein
KAM329_024200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KAM329_024210	COG4235	cytochrome complex assembly
KAM329_024210	COG3088	subunit of a heme lyase
KAM329_024230	COG3046	protein related to deoxyribodipyrimidine photolyase
KAM329_024240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAM329_024270	COG0517	IMP dehydrogenase activity
KAM329_024270	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KAM329_024270	COG0617	tRNA 3'-terminal CCA addition
KAM329_024290	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KAM329_024300	COG0583	DNA-binding transcription factor activity
KAM329_024320	COG4774	siderophore transport
KAM329_024330	COG2203	Gaf domain
KAM329_024330	COG2199	diguanylate cyclase activity
KAM329_024340	COG2200	EAL domain
KAM329_024350	COG4977	sequence-specific DNA binding
KAM329_024350	COG1917	Cupin 2, conserved barrel domain protein
KAM329_024360	COG0583	DNA-binding transcription factor activity
KAM329_024370	COG2910	NAD(P)H-binding
KAM329_024400	COG0626	cystathionine gamma-synthase activity
KAM329_024410	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KAM329_024540	COG1484	DNA-dependent DNA replication
KAM329_024560	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KAM329_024570	COG0830	nickel cation binding
KAM329_024590	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
KAM329_024600	COG0804	urea catabolic process
KAM329_024610	COG0832	Belongs to the urease beta subunit family
KAM329_024620	COG0831	urea catabolic process
KAM329_024630	COG0829	nickel cation binding
KAM329_024650	COG0411	ABC transporter
KAM329_024720	COG2198	Histidine kinase
KAM329_024720	COG2205	protein histidine kinase activity
KAM329_024720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM329_024720	COG0784	Response regulator, receiver
KAM329_024730	COG0745	RESPONSE REGULATOR receiver
KAM329_024760	COG3039	Transposase
KAM329_024790	COG0675	Transposase, IS605 OrfB family
KAM329_024940	COG3550	peptidyl-serine autophosphorylation
KAM329_024990	COG3039	Transposase
KAM329_025100	COG1435	thymidine kinase activity
KAM329_025110	COG1757	Na H antiporter
KAM329_025120	COG2916	Histone family protein nucleoid-structuring protein H-NS
KAM329_025130	COG2096	Adenosyltransferase
KAM329_025140	COG3530	Putative quorum-sensing-regulated virulence factor
KAM329_025150	COG0602	queuosine metabolic process
KAM329_025160	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KAM329_025200	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KAM329_025220	COG0776	regulation of translation
KAM329_025230	COG0539	negative regulation of cytoplasmic translation
KAM329_025240	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KAM329_025250	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KAM329_025310	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KAM329_025320	COG5001	Diguanylate cyclase
KAM329_025320	COG3300	MHYT domain
KAM329_025340	COG0583	DNA-binding transcription factor activity
KAM329_025360	COG0745	RESPONSE REGULATOR receiver
KAM329_025410	COG4989	oxidoreductase activity
KAM329_025420	COG0724	RNA recognition motif
KAM329_025440	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
KAM329_025460	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KAM329_025480	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KAM329_025490	COG1360	Flagellar Motor Protein
KAM329_025500	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM329_025510	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM329_025520	COG0649	NAD binding
KAM329_025520	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM329_025550	COG1034	ATP synthesis coupled electron transport
KAM329_025560	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KAM329_025570	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM329_025580	COG0839	Belongs to the complex I subunit 6 family
KAM329_025590	COG0713	ATP synthesis coupled electron transport
KAM329_025610	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM329_025620	COG1007	ATP synthesis coupled electron transport
KAM329_025630	COG0047	phosphoribosylformylglycinamidine synthase activity
KAM329_025630	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KAM329_025640	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KAM329_025660	COG1645	bacterial-type flagellum-dependent swarming motility
KAM329_025670	COG1160	GTP binding
KAM329_025680	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAM329_025690	COG2976	Protein conserved in bacteria
KAM329_025700	COG0124	histidyl-tRNA synthetase
KAM329_025720	COG1426	Protein conserved in bacteria
KAM329_025740	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KAM329_025750	COG0105	UTP biosynthetic process
KAM329_025780	COG0633	Ferredoxin
KAM329_025790	COG0443	Heat shock 70 kDa protein
KAM329_025800	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KAM329_025820	COG0822	iron-sulfur transferase activity
KAM329_025830	COG1104	cysteine desulfurase activity
KAM329_025860	COG3154	lipid carrier protein
KAM329_025870	COG0826	peptidase U32
KAM329_025880	COG0826	peptidase U32
KAM329_025920	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAM329_025930	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAM329_025940	COG1862	Preprotein translocase
KAM329_025950	COG0343	queuine tRNA-ribosyltransferase activity
KAM329_025960	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KAM329_025970	COG0517	IMP dehydrogenase activity
KAM329_025980	COG0450	alkyl hydroperoxide reductase
KAM329_025990	COG3634	alkyl hydroperoxide reductase activity
KAM329_026000	COG0477	Major facilitator Superfamily
KAM329_026100	COG3385	transposase activity
KAM329_026150	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KAM329_026160	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KAM329_026200	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KAM329_026200	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KAM329_026210	COG0509	glycine decarboxylation via glycine cleavage system
KAM329_026220	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KAM329_026230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KAM329_026240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KAM329_026270	COG2814	Major facilitator Superfamily
KAM329_026290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAM329_026300	COG0601	transmembrane transport
KAM329_026320	COG0625	glutathione transferase activity
KAM329_026330	COG0625	glutathione transferase activity
KAM329_026350	COG0483	inositol monophosphate 1-phosphatase activity
KAM329_026390	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KAM329_026400	COG2056	Na+-H+ antiporter family
KAM329_026410	COG2814	Major facilitator Superfamily
KAM329_026420	COG0583	DNA-binding transcription factor activity
KAM329_026430	COG5001	Diguanylate cyclase
KAM329_026460	COG2050	protein possibly involved in aromatic compounds catabolism
KAM329_026480	COG0277	FAD linked oxidase domain protein
KAM329_026480	COG0247	lactate metabolic process
KAM329_026510	COG3039	Transposase
KAM329_026520	COG1253	flavin adenine dinucleotide binding
KAM329_026530	COG1902	pentaerythritol trinitrate reductase activity
KAM329_026550	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KAM329_026560	COG0647	UMP catabolic process
KAM329_026580	COG0367	asparagine synthase
KAM329_026610	COG0625	glutathione transferase activity
KAM329_026630	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KAM329_026660	COG0564	pseudouridine synthase activity
KAM329_026670	COG5001	Diguanylate cyclase
KAM329_026690	COG0840	transmembrane signaling receptor activity
KAM329_026700	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KAM329_026780	COG0670	Belongs to the BI1 family
KAM329_026790	COG1289	transmembrane transporter activity
KAM329_026800	COG2920	part of a sulfur-relay system
KAM329_026810	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
KAM329_026820	COG0285	dihydrofolate synthase activity
KAM329_026830	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KAM329_026840	COG0101	tRNA pseudouridine synthase activity
KAM329_026860	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KAM329_026870	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KAM329_026890	COG1464	Belongs to the NlpA lipoprotein family
KAM329_026940	COG1119	ATPase activity
KAM329_026950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KAM329_026950	COG0574	Belongs to the PEP-utilizing enzyme family
KAM329_026960	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KAM329_026980	COG1113	amino acid transport
KAM329_027080	COG5433	transposase activity
KAM329_027140	COG1242	4 iron, 4 sulfur cluster binding
KAM329_027150	COG0070	glutamate synthase
KAM329_027150	COG0069	glutamate synthase activity
KAM329_027150	COG0067	glutamate synthase
KAM329_027160	COG0493	'glutamate synthase
KAM329_027170	COG1126	abc transporter atp-binding protein
KAM329_027180	COG0765	amino acid transport
KAM329_027190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM329_027240	COG4104	PAAR repeat-containing protein
KAM329_027260	COG0513	Belongs to the DEAD box helicase family
KAM329_027300	COG3039	Transposase
KAM329_027330	COG3706	GGDEF domain
KAM329_027340	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KAM329_027360	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KAM329_027370	COG0505	Belongs to the CarA family
KAM329_027380	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KAM329_027400	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KAM329_027410	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KAM329_027420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KAM329_027430	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KAM329_027440	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAM329_027450	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
KAM329_027460	COG4139	cobalamin transport
KAM329_027510	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KAM329_027530	COG0023	Translation Initiation Factor
KAM329_027540	COG2119	membrane
KAM329_027610	COG2203	Gaf domain
KAM329_027610	COG2199	diguanylate cyclase activity
KAM329_027620	COG3039	Transposase
KAM329_027650	COG0215	cysteine-tRNA ligase activity
KAM329_027660	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KAM329_027680	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAM329_027690	COG2261	transglycosylase associated protein
KAM329_027700	COG1309	transcriptional regulator
KAM329_027710	COG0604	alcohol dehydrogenase
KAM329_027740	COG0583	DNA-binding transcription factor activity
KAM329_027760	COG0322	excinuclease ABC activity
KAM329_027770	COG2197	response regulator
KAM329_027780	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KAM329_027790	COG2835	tetraacyldisaccharide 4'-kinase activity
KAM329_027800	COG1663	tetraacyldisaccharide 4'-kinase activity
KAM329_027810	COG1132	(ABC) transporter
KAM329_027820	COG2333	competence protein COMEC
KAM329_027820	COG0658	competence protein
KAM329_027850	COG0433	COG0433 Predicted ATPase
KAM329_027860	COG1448	Aminotransferase
KAM329_027890	COG1199	ATP-dependent helicase activity
KAM329_027910	COG0123	including yeast histone deacetylase and acetoin utilization protein
KAM329_027920	COG0477	Major facilitator Superfamily
KAM329_027930	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KAM329_027940	COG1785	Belongs to the alkaline phosphatase family
KAM329_027980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KAM329_027990	COG3706	GGDEF domain
KAM329_028010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM329_028020	COG0765	amino acid transport
KAM329_028030	COG1126	abc transporter atp-binding protein
KAM329_028060	COG0531	amino acid
KAM329_028090	COG1253	flavin adenine dinucleotide binding
KAM329_028100	COG0704	Plays a role in the regulation of phosphate uptake
KAM329_028110	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KAM329_028120	COG0581	inorganic phosphate transmembrane transporter activity
KAM329_028130	COG0573	inorganic phosphate transmembrane transporter activity
KAM329_028140	COG0590	tRNA wobble adenosine to inosine editing
KAM329_028160	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KAM329_028180	COG0675	Transposase, IS605 OrfB family
KAM329_028220	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KAM329_028230	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KAM329_028240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KAM329_028250	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KAM329_028300	COG2716	regulation of RNA biosynthetic process
KAM329_028310	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KAM329_028330	COG2239	Acts as a magnesium transporter
KAM329_028360	COG3951	Flagellar rod assembly protein muramidase FlgJ
KAM329_028360	COG1705	Flagellar rod assembly protein muramidase FlgJ
KAM329_028370	COG1706	bacterial-type flagellum-dependent cell motility
KAM329_028380	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KAM329_028410	COG1749	Flagellar hook protein flgE
KAM329_028440	COG1815	bacterial-type flagellum-dependent cell motility
KAM329_028450	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KAM329_028460	COG0784	Response regulator, receiver
KAM329_028460	COG0835	chemotaxis
KAM329_028470	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
KAM329_028500	COG0622	Phosphoesterase
KAM329_028510	COG0675	Transposase, IS605 OrfB family
KAM329_028530	COG4166	transmembrane transport
KAM329_028560	COG0675	Transposase, IS605 OrfB family
KAM329_028580	COG0697	spore germination
KAM329_028650	COG1278	Cold shock
KAM329_028680	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KAM329_028730	COG3132	Protein of unknown function, DUF480
KAM329_028750	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAM329_028790	COG3206	protein involved in exopolysaccharide biosynthesis
KAM329_028790	COG0489	protein tyrosine kinase activity
KAM329_028800	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KAM329_028970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KAM329_028990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KAM329_029100	COG1091	dTDP-4-dehydrorhamnose reductase activity
KAM329_029120	COG3039	Transposase
KAM329_029160	COG1737	Transcriptional regulator
KAM329_029170	COG0469	pyruvate kinase activity
KAM329_029190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM329_029200	COG1960	acyl-CoA dehydrogenase activity
KAM329_029220	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KAM329_029260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM329_029270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM329_029280	COG1309	transcriptional regulator
KAM329_029310	COG1946	Acyl-CoA thioesterase
KAM329_029340	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KAM329_029360	COG0009	L-threonylcarbamoyladenylate synthase
KAM329_029370	COG0613	PHP domain protein
KAM329_029380	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KAM329_029390	COG0512	Glutamine amidotransferase of anthranilate synthase
KAM329_029390	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KAM329_029400	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KAM329_029410	COG0135	phosphoribosylanthranilate isomerase activity
KAM329_029410	COG0134	indole-3-glycerol-phosphate synthase activity
KAM329_029420	COG0133	tryptophan synthase activity
KAM329_029430	COG0159	tryptophan synthase activity
KAM329_029450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KAM329_029470	COG1396	sequence-specific DNA binding
KAM329_029480	COG3550	peptidyl-serine autophosphorylation
KAM329_029520	COG0583	DNA-binding transcription factor activity
KAM329_029540	COG5507	3-demethylubiquinone-9 3-methyltransferase
KAM329_029550	COG2814	Major facilitator Superfamily
KAM329_029560	COG0109	protoheme IX farnesyltransferase activity
KAM329_029570	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KAM329_029580	COG1845	cytochrome c oxidase, subunit III
KAM329_029590	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KAM329_029600	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KAM329_029610	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KAM329_029620	COG0583	DNA-binding transcription factor activity
KAM329_029660	COG1846	Transcriptional regulator
KAM329_029690	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
KAM329_029730	COG0745	RESPONSE REGULATOR receiver
KAM329_029750	COG0708	Exodeoxyribonuclease III
KAM329_029770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM329_029780	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM329_029810	COG0095	Lipoate-protein ligase
KAM329_029870	COG0640	Transcriptional regulator
KAM329_029890	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAM329_029910	COG1285	pathogenesis
KAM329_029980	COG0484	heat shock protein binding
KAM329_029990	COG0443	Heat shock 70 kDa protein
KAM329_030000	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KAM329_030020	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KAM329_030030	COG3706	GGDEF domain
KAM329_030040	COG0497	DNA recombination
KAM329_030060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM329_030070	COG0577	efflux transmembrane transporter activity
KAM329_030070	COG1136	(ABC) transporter
KAM329_030080	COG1538	Outer membrane efflux protein
KAM329_030090	COG2375	cellular response to nickel ion
KAM329_030100	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAM329_030110	COG2916	Histone family protein nucleoid-structuring protein H-NS
KAM329_030120	COG0583	DNA-binding transcription factor activity
KAM329_030130	COG3048	D-serine ammonia-lyase activity
KAM329_030150	COG0538	isocitrate dehydrogenase activity
KAM329_030230	COG0456	acetyltransferase
KAM329_030240	COG1187	pseudouridine synthase activity
KAM329_030260	COG0482	sulfurtransferase activity
KAM329_030270	COG2915	High frequency lysogenization protein hflD homolog
KAM329_030280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KAM329_030290	COG2850	peptidyl-arginine hydroxylation
KAM329_030310	COG1196	nuclear chromosome segregation
KAM329_030310	COG3264	Mechanosensitive ion channel
KAM329_030370	COG0281	malic enzyme
KAM329_030380	COG0746	molybdenum cofactor guanylyltransferase activity
KAM329_030390	COG1763	Mo-molybdopterin cofactor biosynthetic process
KAM329_030400	COG1289	transmembrane transporter activity
KAM329_030410	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KAM329_030470	COG3220	belongs to the UPF0276 family
KAM329_030490	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KAM329_030580	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KAM329_030590	COG0083	homoserine kinase activity
KAM329_030610	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
KAM329_030620	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
KAM329_030660	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KAM329_030680	COG0745	RESPONSE REGULATOR receiver
KAM329_030690	COG4988	ABC transporter
KAM329_030700	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KAM329_030750	COG1720	tRNA m6t6A37 methyltransferase activity
KAM329_030780	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KAM329_030790	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KAM329_030800	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM329_030820	COG2190	(PTS) system
KAM329_030830	COG3038	cytochrome b561
KAM329_030850	COG0420	3'-5' exonuclease activity
KAM329_030870	COG1247	-acetyltransferase
KAM329_030880	COG2974	May be involved in recombination
KAM329_030900	COG0405	Gamma-glutamyltransferase
KAM329_030910	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KAM329_030910	COG4651	solute:proton antiporter activity
KAM329_031010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAM329_031020	COG1917	Cupin 2, conserved barrel domain protein
KAM329_031020	COG1396	sequence-specific DNA binding
KAM329_031030	COG1012	belongs to the aldehyde dehydrogenase family
KAM329_031060	COG0531	amino acid
KAM329_031070	COG0531	amino acid
KAM329_031090	COG1283	sodium-dependent phosphate transmembrane transporter activity
KAM329_031110	COG3384	dioxygenase
KAM329_031120	COG2205	protein histidine kinase activity
KAM329_031120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM329_031130	COG2205	protein histidine kinase activity
KAM329_031130	COG2198	Histidine kinase
KAM329_031130	COG0784	Response regulator, receiver
KAM329_031130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM329_031160	COG2205	protein histidine kinase activity
KAM329_031160	COG0784	Response regulator, receiver
KAM329_031170	COG0582	viral genome integration into host DNA
KAM329_031240	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM329_031320	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM329_031330	COG3041	Addiction module toxin RelE StbE family
KAM329_031430	COG5002	protein histidine kinase activity
KAM329_031430	COG2176	DNA-directed DNA polymerase activity
KAM329_031510	COG1192	Involved in chromosome partitioning
KAM329_031580	COG1376	ErfK ybiS ycfS ynhG family protein
KAM329_031580	COG1388	LysM domain
KAM329_031610	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
KAM329_031620	COG0791	NLP P60 protein
KAM329_031640	COG3118	belongs to the thioredoxin family
KAM329_031660	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KAM329_031670	COG0788	formyltetrahydrofolate deformylase activity
KAM329_031720	COG0741	lytic transglycosylase activity
KAM329_031720	COG0739	heme binding
KAM329_031720	COG1196	nuclear chromosome segregation
KAM329_031730	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KAM329_031740	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KAM329_031750	COG0673	inositol 2-dehydrogenase activity
KAM329_031800	COG1032	radical SAM domain protein
KAM329_031810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM329_031830	COG3706	GGDEF domain
KAM329_031840	COG1752	Esterase of the alpha-beta hydrolase superfamily
KAM329_031850	COG0733	neurotransmitter:sodium symporter activity
KAM329_031910	COG0281	malic enzyme
KAM329_031920	COG2207	Transcriptional regulator
KAM329_031960	COG2233	PERMEase
KAM329_031970	COG0095	Lipoate-protein ligase
KAM329_031980	COG1115	amino acid carrier protein
KAM329_031990	COG0019	diaminopimelate decarboxylase activity
KAM329_032010	COG0678	peroxiredoxin activity
KAM329_032020	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KAM329_032040	COG1126	abc transporter atp-binding protein
KAM329_032050	COG0765	amino acid transport
KAM329_032060	COG4597	amino acid ABC transporter
KAM329_032070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM329_032110	COG0545	Peptidyl-prolyl cis-trans isomerase
KAM329_032170	COG4783	chaperone-mediated protein folding
KAM329_032190	COG5002	protein histidine kinase activity
KAM329_032200	COG0745	RESPONSE REGULATOR receiver
KAM329_032210	COG0346	lactoylglutathione lyase activity
KAM329_032220	COG3706	GGDEF domain
KAM329_032230	COG3284	Transcriptional regulator
KAM329_032260	COG0697	spore germination
KAM329_032280	COG0667	Aldo Keto reductase
KAM329_032310	COG3290	protein histidine kinase activity
KAM329_032330	COG1566	PFAM secretion protein HlyD family protein
KAM329_032380	COG0602	queuosine metabolic process
KAM329_032390	COG1328	CTP reductase activity
KAM329_032410	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KAM329_032420	COG3115	cell septum assembly
KAM329_032430	COG1196	nuclear chromosome segregation
KAM329_032450	COG2860	membrane
KAM329_032470	COG3108	Peptidase M15
KAM329_032480	COG2989	Protein conserved in bacteria
KAM329_032510	COG0463	Glycosyl transferase, family 2
KAM329_032540	COG0366	Alpha amylase catalytic
KAM329_032630	COG3706	GGDEF domain
KAM329_032640	COG0037	tRNA processing
KAM329_032670	COG0488	(ABC) transporter
KAM329_032690	COG0531	amino acid
KAM329_032700	COG0814	amino acid
KAM329_032730	COG0825	malonyl-CoA metabolic process
KAM329_032740	COG0587	DNA-directed DNA polymerase activity
KAM329_032750	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KAM329_032760	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAM329_032770	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAM329_032780	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KAM329_032790	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAM329_032820	COG0750	zinc metalloprotease
KAM329_032830	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KAM329_032840	COG0575	Belongs to the CDS family
KAM329_032850	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KAM329_032860	COG0233	cytoplasmic translational termination
KAM329_032870	COG0528	UMP kinase activity
KAM329_032880	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KAM329_032890	COG0052	Belongs to the universal ribosomal protein uS2 family
KAM329_032900	COG0024	Methionine aminopeptidase
KAM329_032910	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KAM329_032920	COG2171	N-acyltransferase activity
KAM329_032940	COG1263	PTS System
KAM329_032940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM329_032960	COG4580	involved in the transport of maltose and maltodextrins
KAM329_032980	COG0564	pseudouridine synthase activity
KAM329_032990	COG3098	single-species biofilm formation
KAM329_033040	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
KAM329_033060	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KAM329_033060	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KAM329_033090	COG1611	Belongs to the LOG family
KAM329_033100	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KAM329_033110	COG0473	3-isopropylmalate dehydrogenase activity
KAM329_033130	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
KAM329_033140	COG2363	Small membrane protein
KAM329_033160	COG0583	DNA-binding transcription factor activity
KAM329_033170	COG0840	transmembrane signaling receptor activity
KAM329_033180	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KAM329_033210	COG1477	protein flavinylation
KAM329_033220	COG2871	sodium ion transport
KAM329_033230	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM329_033240	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM329_033250	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM329_033260	COG1805	sodium ion transport
KAM329_033270	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM329_033280	COG0271	Belongs to the BolA IbaG family
KAM329_033290	COG2813	Specifically methylates the guanine in position
KAM329_033310	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KAM329_033330	COG2211	Major facilitator Superfamily
KAM329_033350	COG1666	GTP binding
KAM329_033360	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KAM329_033380	COG1393	Belongs to the ArsC family
KAM329_033390	COG0798	PFAM Bile acid sodium symporter
KAM329_033410	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KAM329_033460	COG0582	viral genome integration into host DNA
KAM329_033480	COG3335	DDE superfamily endonuclease
KAM329_033510	COG3311	Transcriptional regulator
KAM329_033530	COG1196	nuclear chromosome segregation
KAM329_033720	COG2003	Belongs to the UPF0758 family
KAM329_033810	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KAM329_033840	COG2189	Belongs to the N(4) N(6)-methyltransferase family
KAM329_033870	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KAM329_033880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KAM329_033890	COG1151	hydroxylamine reductase activity
KAM329_033900	COG0783	Belongs to the Dps family
KAM329_033950	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KAM329_033980	COG4221	oxidoreductase activity
KAM329_034000	COG0415	Belongs to the DNA photolyase family
KAM329_034010	COG0789	Transcriptional regulator
KAM329_034020	COG3272	Protein of unknown function (DUF1722)
KAM329_034070	COG0077	Prephenate dehydratase
KAM329_034070	COG1605	Chorismate mutase
KAM329_034140	COG3039	Transposase
KAM329_034250	COG1484	DNA-dependent DNA replication
KAM329_034260	COG4584	PFAM Integrase catalytic
KAM329_034280	COG3415	Transposase
KAM329_034280	COG2801	Transposase and inactivated derivatives
KAM329_034330	COG2916	Histone family protein nucleoid-structuring protein H-NS
KAM329_034360	COG3039	Transposase
KAM329_034420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KAM329_034500	COG4584	PFAM Integrase catalytic
KAM329_034530	COG2133	pyrroloquinoline quinone binding
KAM329_034550	COG1349	DNA-binding transcription factor activity
KAM329_034560	COG2084	Dehydrogenase
KAM329_034580	COG0235	Class ii aldolase
KAM329_034590	COG3622	Belongs to the hyi family
KAM329_034600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KAM329_034610	COG2610	gluconate transmembrane transporter activity
KAM329_034650	COG0300	oxidoreductase activity
KAM329_034700	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KAM329_034720	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KAM329_034740	COG3813	Protein conserved in bacteria
KAM329_034760	COG0826	peptidase U32
KAM329_034770	COG1280	lysine exporter protein (LysE YggA)
KAM329_034790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KAM329_034830	COG3275	phosphorelay sensor kinase activity
KAM329_034840	COG3279	Response regulator of the LytR AlgR family
KAM329_034860	COG1966	Carbon starvation protein
KAM329_034920	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KAM329_034950	COG4263	nitrous-oxide reductase activity
KAM329_034960	COG3901	Regulator of nitric oxide reductase transcription
KAM329_034960	COG0348	domain, Protein
KAM329_034970	COG0114	fumarate hydratase activity
KAM329_034990	COG0506	proline dehydrogenase activity
KAM329_034990	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KAM329_034990	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KAM329_035000	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KAM329_035030	COG0737	Belongs to the 5'-nucleotidase family
KAM329_035070	COG2204	response regulator
KAM329_035080	COG0545	Peptidyl-prolyl cis-trans isomerase
KAM329_035100	COG2900	Belongs to the SlyX family
KAM329_035110	COG1047	Peptidyl-prolyl cis-trans
KAM329_035120	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KAM329_035140	COG0784	Response regulator, receiver
KAM329_035140	COG0835	chemotaxis
KAM329_035150	COG0429	hydrolase of the alpha beta-hydrolase fold
KAM329_035160	COG5001	Diguanylate cyclase
KAM329_035160	COG3706	GGDEF domain
KAM329_035160	COG2203	Gaf domain
KAM329_035160	COG4251	negative regulation of phosphorylation
KAM329_035170	COG3089	Belongs to the UPF0270 family
KAM329_035180	COG3954	Phosphoribulokinase
KAM329_035210	COG1765	OsmC-like protein
KAM329_035230	COG2226	methyltransferase
KAM329_035270	COG2205	protein histidine kinase activity
KAM329_035280	COG2814	Major facilitator Superfamily
KAM329_035330	COG0748	coenzyme F420 binding
KAM329_035340	COG3721	Heme iron utilization protein
KAM329_035360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAM329_035410	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KAM329_035430	COG0463	Glycosyl transferase, family 2
KAM329_035440	COG0741	lytic transglycosylase activity
KAM329_035440	COG0739	heme binding
KAM329_035440	COG1196	nuclear chromosome segregation
KAM329_035450	COG0488	(ABC) transporter
KAM329_035470	COG2252	PERMEase
KAM329_035480	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KAM329_035490	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KAM329_035500	COG3178	'Phosphotransferase
KAM329_035510	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KAM329_035530	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KAM329_035540	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KAM329_035550	COG2967	ApaG domain
KAM329_035560	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KAM329_035570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KAM329_035580	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KAM329_035590	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KAM329_035600	COG3314	Sporulation integral membrane protein YlbJ
KAM329_035610	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KAM329_035620	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KAM329_035630	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KAM329_035640	COG0142	geranyltranstransferase activity
KAM329_035650	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
KAM329_035660	COG0330	HflC and HflK could
KAM329_035670	COG0330	HflC and HflK could
KAM329_035680	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KAM329_035690	COG1923	regulation of RNA biosynthetic process
KAM329_035700	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KAM329_035710	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KAM329_035730	COG0802	atpase or kinase
KAM329_035740	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KAM329_035740	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KAM329_035780	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KAM329_035790	COG2011	ABC-type metal ion transport system permease component
KAM329_035800	COG1464	Belongs to the NlpA lipoprotein family
KAM329_035840	COG0784	Response regulator, receiver
KAM329_035840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM329_035840	COG2198	Histidine kinase
KAM329_035840	COG2205	protein histidine kinase activity
KAM329_035880	COG5002	protein histidine kinase activity
KAM329_035880	COG0784	Response regulator, receiver
KAM329_035880	COG2198	Histidine kinase
KAM329_035920	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
KAM329_035950	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KAM329_035960	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
KAM329_035970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KAM329_035980	COG2716	regulation of RNA biosynthetic process
KAM329_035990	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KAM329_036000	COG3013	Belongs to the UPF0304 family
KAM329_036020	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KAM329_036030	COG0280	phosphate acetyltransferase
KAM329_036030	COG0857	belongs to the CobB CobQ family
KAM329_036060	COG4804	nuclease activity
KAM329_036090	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KAM329_036110	COG3077	Addiction module antitoxin, RelB DinJ family
KAM329_036120	COG3385	transposase activity
KAM329_036160	COG5489	Protein of unknown function (DUF736)
KAM329_036240	COG1192	Involved in chromosome partitioning
KAM329_036270	COG4959	Type IV secretory pathway protease TraF
KAM329_036310	COG1127	ABC transporter
KAM329_036320	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KAM329_036390	COG0583	DNA-binding transcription factor activity
KAM329_036440	COG3846	protein secretion by the type IV secretion system
KAM329_036470	COG3451	type IV secretory pathway VirB4
KAM329_036490	COG3838	Conjugal transfer protein Trbc
KAM329_036500	COG4962	Type ii secretion system protein e
KAM329_036560	COG2076	Multidrug Resistance protein
KAM329_036600	COG2003	Belongs to the UPF0758 family
KAM329_036610	COG4804	nuclease activity
KAM329_036670	COG4962	Type ii secretion system protein e
KAM329_036680	COG3838	Conjugal transfer protein Trbc
KAM329_036700	COG3451	type IV secretory pathway VirB4
KAM329_036780	COG0440	acetolactate synthase activity
KAM329_036790	COG0028	Belongs to the TPP enzyme family
KAM329_036820	COG0671	phosphoesterase, PA-phosphatase related
KAM329_036840	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KAM329_036850	COG0473	3-isopropylmalate dehydrogenase activity
KAM329_036860	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KAM329_036870	COG0066	3-isopropylmalate dehydratase activity
KAM329_036900	COG4143	(ABC) transporter
KAM329_036910	COG1178	ABC-type Fe3 transport system permease component
KAM329_036920	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
KAM329_036940	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KAM329_036960	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KAM329_036980	COG0316	Belongs to the HesB IscA family
KAM329_037000	COG0038	chloride channel
KAM329_037010	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KAM329_037040	COG0671	phosphoesterase, PA-phosphatase related
KAM329_037060	COG0583	DNA-binding transcription factor activity
KAM329_037070	COG2076	Multidrug Resistance protein
KAM329_037090	COG0346	lactoylglutathione lyase activity
KAM329_037100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KAM329_037110	COG1643	Atp-dependent helicase
KAM329_037130	COG1489	DNA binding
KAM329_037140	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KAM329_037150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KAM329_037170	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KAM329_037180	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KAM329_037190	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KAM329_037210	COG0842	Transport permease protein
KAM329_037220	COG1131	(ABC) transporter
KAM329_037250	COG0163	prenyltransferase activity
KAM329_037260	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KAM329_037270	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KAM329_037300	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
KAM329_037330	COG1136	(ABC) transporter
KAM329_037450	COG2801	Transposase and inactivated derivatives
KAM329_037460	COG0529	Catalyzes the synthesis of activated sulfate
KAM329_037470	COG0471	metal ion transport
KAM329_037470	COG3273	potassium ion transport
KAM329_037480	COG2895	sulfate adenylyltransferase (ATP) activity
KAM329_037490	COG0175	sulfate reduction
KAM329_037500	COG1648	precorrin-2 dehydrogenase activity
KAM329_037500	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KAM329_037510	COG0330	HflC and HflK could
KAM329_037520	COG1585	Membrane protein implicated in regulation of membrane protease activity
KAM329_037540	COG0673	inositol 2-dehydrogenase activity
KAM329_037560	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KAM329_037570	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KAM329_037580	COG3036	rescue of stalled ribosome
KAM329_037610	COG0138	bifunctional purine biosynthesis protein purh
KAM329_037680	COG3335	DDE superfamily endonuclease
KAM329_037690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KAM329_037700	COG0358	DNA primase activity
KAM329_037710	COG1610	YqeY-like protein
KAM329_037720	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KAM329_037730	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KAM329_037750	COG1388	LysM domain
KAM329_037750	COG4942	peptidase
KAM329_037760	COG1238	metal cluster binding
KAM329_037770	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KAM329_037780	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KAM329_037790	COG0585	pseudouridine synthase activity
KAM329_037810	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KAM329_037820	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KAM329_037830	COG0148	phosphopyruvate hydratase activity
KAM329_037840	COG0504	CTP synthase activity
KAM329_037850	COG3956	TIGRFAM MazG family protein
KAM329_037860	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KAM329_037870	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KAM329_037890	COG4807	Protein conserved in bacteria
KAM329_037900	COG3023	N-Acetylmuramoyl-L-alanine amidase
KAM329_037910	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KAM329_037920	COG1381	Involved in DNA repair and RecF pathway recombination
KAM329_037940	COG0571	ribonuclease III activity
KAM329_037950	COG0681	Belongs to the peptidase S26 family
KAM329_037960	COG0481	GTPase activity
KAM329_037990	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
KAM329_038000	COG1595	DNA-templated transcription, initiation
KAM329_038010	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KAM329_038030	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KAM329_038050	COG0583	DNA-binding transcription factor activity
KAM329_038110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAM329_038130	COG0126	phosphoglycerate kinase activity
KAM329_038140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KAM329_038150	COG1940	carbohydrate kinase activity
KAM329_038160	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KAM329_038180	COG4991	sh3 domain protein
KAM329_038190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KAM329_038220	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KAM329_038230	COG1028	Short-chain dehydrogenase reductase Sdr
KAM329_038260	COG1505	serine-type exopeptidase activity
KAM329_038270	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KAM329_038280	COG0765	amino acid transport
KAM329_038290	COG0765	amino acid transport
KAM329_038300	COG1126	abc transporter atp-binding protein
KAM329_038310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM329_038320	COG3174	membrane
KAM329_038330	COG0110	maltose O-acetyltransferase activity
KAM329_038390	COG1942	4-Oxalocrotonate Tautomerase
KAM329_038410	COG0583	DNA-binding transcription factor activity
KAM329_038420	COG0165	Argininosuccinate lyase
KAM329_038430	COG0137	argininosuccinate synthase activity
KAM329_038450	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KAM329_038460	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KAM329_038480	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KAM329_038490	COG5001	Diguanylate cyclase
KAM329_038490	COG3447	MASE1 domain protein
KAM329_038490	COG5002	protein histidine kinase activity
KAM329_038500	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KAM329_038570	COG0583	DNA-binding transcription factor activity
KAM329_038580	COG1380	Effector of murein hydrolase LrgA
KAM329_038590	COG1346	cytolysis
KAM329_038600	COG0460	homoserine dehydrogenase
KAM329_038600	COG0527	aspartate kinase activity
KAM329_038610	COG0626	cystathionine gamma-synthase activity
KAM329_038640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM329_038650	COG0814	amino acid
KAM329_038660	COG1218	3'(2'),5'-bisphosphate nucleotidase
KAM329_038670	COG0494	nUDIX hydrolase
KAM329_038680	COG1011	Hydrolase
KAM329_038690	COG1902	pentaerythritol trinitrate reductase activity
KAM329_038710	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KAM329_038740	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
KAM329_038760	COG3156	type II secretion system protein K
KAM329_038770	COG4795	General secretion pathway protein
KAM329_038780	COG2165	general secretion pathway protein
KAM329_038800	COG2165	general secretion pathway protein
KAM329_038810	COG1459	type II secretion system
KAM329_038820	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KAM329_038840	COG3031	protein transport across the cell outer membrane
KAM329_038860	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KAM329_038870	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KAM329_038910	COG3133	Outer membrane lipoprotein
KAM329_038920	COG3025	triphosphatase activity
KAM329_038930	COG1392	Phosphate transport regulator
KAM329_038940	COG0306	phosphate transporter
KAM329_038950	COG0617	tRNA 3'-terminal CCA addition
KAM329_038960	COG3409	Peptidoglycan-binding domain 1 protein
KAM329_038960	COG3267	Type II secretory pathway component ExeA
KAM329_038980	COG1194	a g-specific adenine glycosylase
KAM329_038990	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
KAM329_039020	COG3240	lipase activity
KAM329_039040	COG3009	Protein conserved in bacteria
KAM329_039050	COG3008	intermembrane lipid transfer
KAM329_039050	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KAM329_039060	COG2995	paraquat-inducible protein a
KAM329_039080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAM329_039090	COG2203	Gaf domain
KAM329_039090	COG3706	GGDEF domain
KAM329_039090	COG4251	negative regulation of phosphorylation
KAM329_039090	COG5001	Diguanylate cyclase
KAM329_039100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KAM329_039110	COG2813	Specifically methylates the guanine in position
KAM329_039120	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KAM329_039130	COG0297	glycogen (starch) synthase activity
KAM329_039160	COG1757	Na H antiporter
KAM329_039170	COG0583	DNA-binding transcription factor activity
KAM329_039180	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KAM329_039190	COG3842	ATPase activity
KAM329_039200	COG1176	ABC-type spermidine putrescine transport system, permease component I
KAM329_039210	COG1177	transmembrane transport
KAM329_039220	COG1012	belongs to the aldehyde dehydrogenase family
KAM329_039230	COG0109	protoheme IX farnesyltransferase activity
KAM329_039290	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KAM329_039310	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KAM329_039310	COG1565	acr, cog1565
KAM329_039320	COG1444	tRNA N-acetyltransferase activity
KAM329_039360	COG1803	Methylglyoxal synthase
KAM329_039390	COG0252	asparaginase activity
KAM329_039430	COG1263	PTS System
KAM329_039430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM329_039440	COG0366	Alpha amylase catalytic
KAM329_039450	COG0110	maltose O-acetyltransferase activity
KAM329_039460	COG1522	sequence-specific DNA binding
KAM329_039520	COG3068	Protein conserved in bacteria
KAM329_039540	COG0739	heme binding
KAM329_039580	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
KAM329_039590	COG1121	(ABC) transporter
KAM329_039600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KAM329_039610	COG0583	DNA-binding transcription factor activity
KAM329_039630	COG1573	uracil-dna glycosylase
KAM329_039640	COG2962	Rard protein
KAM329_039650	COG2827	Endonuclease containing a URI domain
KAM329_039680	COG1842	Phage shock protein A
KAM329_039690	COG0204	Acyl-transferase
KAM329_039730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KAM329_039750	COG0484	heat shock protein binding
KAM329_039830	COG5433	transposase activity
KAM329_039850	COG3039	Transposase
KAM329_039930	COG1289	transmembrane transporter activity
KAM329_039940	COG1566	PFAM secretion protein HlyD family protein
KAM329_039970	COG1051	belongs to the nudix hydrolase family
KAM329_039980	COG3150	esterase
KAM329_040000	COG3151	Protein conserved in bacteria
KAM329_040010	COG0494	nUDIX hydrolase
KAM329_040020	COG1538	Outer membrane efflux protein
KAM329_040040	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KAM329_040040	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KAM329_040050	COG1560	Kdo2-lipid A biosynthetic process
KAM329_040080	COG2771	luxR family
KAM329_040090	COG3916	Acyl-homoserine-lactone synthase
KAM329_040110	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
KAM329_040120	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM329_040120	COG2213	PTS system mannitol-specific
KAM329_040130	COG0246	Mannitol dehydrogenase
KAM329_040140	COG3722	fumarate hydratase activity
KAM329_040150	COG3263	regulation of cellular component size
KAM329_040190	COG1671	Belongs to the UPF0178 family
KAM329_040220	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KAM329_040230	COG0513	Belongs to the DEAD box helicase family
KAM329_040270	COG1575	Belongs to the MenA family. Type 1 subfamily
KAM329_040280	COG1169	isochorismate synthase
KAM329_040290	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KAM329_040300	COG0596	Alpha beta hydrolase
KAM329_040310	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KAM329_040330	COG0318	PFAM AMP-dependent synthetase and ligase
KAM329_040340	COG3291	Pkd domain containing protein
KAM329_040350	COG2949	membrane
KAM329_040360	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KAM329_040380	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KAM329_040440	COG2873	o-acetylhomoserine
KAM329_040460	COG1979	alcohol dehydrogenase
KAM329_040490	COG4221	oxidoreductase activity
KAM329_040530	COG1285	pathogenesis
KAM329_040560	COG1368	sulfuric ester hydrolase activity
KAM329_040570	COG1522	sequence-specific DNA binding
KAM329_040590	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KAM329_040610	COG1546	Belongs to the CinA family
KAM329_040610	COG1058	Belongs to the CinA family
KAM329_040620	COG1988	membrane-bound metal-dependent
KAM329_040640	COG0561	phosphatase activity
KAM329_040650	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KAM329_040670	COG1011	Hydrolase
KAM329_040700	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KAM329_040710	COG0019	diaminopimelate decarboxylase activity
KAM329_040730	COG1965	Belongs to the frataxin family
KAM329_040740	COG0400	carboxylic ester hydrolase activity
KAM329_040750	COG3072	Adenylate cyclase
KAM329_040760	COG0181	hydroxymethylbilane synthase activity
KAM329_040780	COG2959	enzyme of heme biosynthesis
KAM329_040790	COG3071	HemY protein
KAM329_040810	COG0312	modulator of DNA gyrase
KAM329_040820	COG3028	Belongs to the UPF0307 family
KAM329_040840	COG2926	Belongs to the UPF0265 family
KAM329_040860	COG1396	sequence-specific DNA binding
KAM329_040870	COG3135	benzoate transporter
KAM329_040940	COG3047	cAMP biosynthetic process
KAM329_040960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KAM329_040970	COG2197	response regulator
KAM329_041030	COG5642	Protein of unknown function (DUF2384)
KAM329_041050	COG5433	transposase activity
KAM329_041060	COG5433	transposase activity
KAM329_041070	COG3328	transposase activity
KAM329_041080	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM329_041180	COG0457	Tetratricopeptide repeat
KAM329_041190	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KAM329_041200	COG1215	transferase activity, transferring glycosyl groups
KAM329_041210	COG0455	bacterial-type flagellum organization
KAM329_041250	COG5499	transcription regulator containing HTH domain
KAM329_041260	COG2916	Histone family protein nucleoid-structuring protein H-NS
KAM329_041280	COG3039	Transposase
KAM329_041410	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KAM329_041420	COG5642	Protein of unknown function (DUF2384)
KAM329_041430	COG2801	Transposase and inactivated derivatives
KAM329_041450	COG1484	DNA-dependent DNA replication
KAM329_041460	COG1484	DNA-dependent DNA replication
KAM329_041470	COG4584	PFAM Integrase catalytic
KAM329_041490	COG5499	transcription regulator containing HTH domain
KAM329_041580	COG0210	DNA helicase
KAM329_041620	COG2850	peptidyl-arginine hydroxylation
KAM329_041660	COG2916	Histone family protein nucleoid-structuring protein H-NS
KAM329_041750	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KAM329_041760	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KAM329_041820	COG1396	sequence-specific DNA binding
KAM329_041880	COG1278	Cold shock
KAM329_041940	COG3706	GGDEF domain
KAM329_041950	COG0347	Belongs to the P(II) protein family
KAM329_041960	COG0004	ammonium transporteR
KAM329_042000	COG0346	lactoylglutathione lyase activity
KAM329_042030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KAM329_042040	COG1074	ATP-dependent DNA helicase activity
KAM329_042050	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KAM329_042060	COG2259	Doxx family
KAM329_042070	COG1741	Belongs to the pirin family
KAM329_042090	COG0583	DNA-binding transcription factor activity
KAM329_042140	COG1175	transmembrane transport
KAM329_042160	COG3842	ATPase activity
KAM329_042220	COG0456	acetyltransferase
KAM329_042230	COG0753	catalase activity
KAM329_042270	COG0494	nUDIX hydrolase
KAM329_042280	COG0628	permease
KAM329_042300	COG2957	Belongs to the agmatine deiminase family
KAM329_042330	COG2957	Belongs to the agmatine deiminase family
KAM329_042340	COG0583	DNA-binding transcription factor activity
KAM329_042370	COG1461	Dihydroxyacetone kinase
KAM329_042380	COG2376	Dihydroxyacetone kinase
KAM329_042390	COG2252	PERMEase
KAM329_042400	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KAM329_042410	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KAM329_042420	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KAM329_042430	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KAM329_042440	COG0049	tRNA binding
KAM329_042450	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KAM329_042460	COG2168	tRNA wobble position uridine thiolation
KAM329_042480	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KAM329_042490	COG0251	oxidation-reduction process
KAM329_042500	COG2964	Protein conserved in bacteria
KAM329_042510	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KAM329_042520	COG0085	RNA polymerase activity
KAM329_042530	COG0222	ribosome binding
KAM329_042540	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KAM329_042550	COG0081	regulation of translation
KAM329_042560	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KAM329_042570	COG0250	Participates in transcription elongation, termination and antitermination
KAM329_042590	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KAM329_042620	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KAM329_042630	COG0569	domain protein
KAM329_042640	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KAM329_042650	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KAM329_042660	COG3005	denitrification pathway
KAM329_042670	COG0243	molybdopterin cofactor binding
KAM329_042740	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KAM329_042760	COG2204	response regulator
KAM329_042780	COG2205	protein histidine kinase activity
KAM329_042810	COG0517	IMP dehydrogenase activity
KAM329_042810	COG0516	GMP reductase activity
KAM329_042830	COG1522	sequence-specific DNA binding
KAM329_042840	COG2502	aspartate--ammonia ligase
KAM329_042870	COG0583	DNA-binding transcription factor activity
KAM329_042880	COG0542	response to heat
KAM329_042900	COG0564	pseudouridine synthase activity
KAM329_042910	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAM329_042920	COG3681	Belongs to the UPF0597 family
KAM329_042930	COG2964	Protein conserved in bacteria
KAM329_042940	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KAM329_042950	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KAM329_042960	COG1979	alcohol dehydrogenase
KAM329_042970	COG2207	Transcriptional regulator
KAM329_042980	COG3040	lipid binding
KAM329_043020	COG0583	DNA-binding transcription factor activity
KAM329_043050	COG0540	Belongs to the ATCase OTCase family
KAM329_043060	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
KAM329_043070	COG1438	arginine binding
KAM329_043080	COG1288	antiporter activity
KAM329_043090	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KAM329_043170	COG3250	beta-galactosidase activity
KAM329_043190	COG1609	Transcriptional regulator
KAM329_043200	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KAM329_043220	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KAM329_043230	COG2017	converts alpha-aldose to the beta-anomer
KAM329_043240	COG0667	Aldo Keto reductase
KAM329_043250	COG1968	undecaprenyl-diphosphatase activity
KAM329_043260	COG3806	Anti-sigma factor
KAM329_043270	COG1595	DNA-templated transcription, initiation
KAM329_043310	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KAM329_043320	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KAM329_043330	COG0477	Major facilitator Superfamily
KAM329_043360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM329_043370	COG1131	(ABC) transporter
KAM329_043380	COG0842	Transport permease protein
KAM329_043390	COG0842	Transport permease protein
KAM329_043400	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KAM329_043420	COG2116	formate transmembrane transporter activity
KAM329_043430	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KAM329_043430	COG1648	precorrin-2 dehydrogenase activity
KAM329_043440	COG2239	Acts as a magnesium transporter
KAM329_043450	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KAM329_043470	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KAM329_043490	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KAM329_043510	COG0514	ATP-dependent DNA helicase (RecQ)
KAM329_043520	COG2050	protein possibly involved in aromatic compounds catabolism
KAM329_043540	COG2258	MOSC domain
KAM329_043550	COG1177	transmembrane transport
KAM329_043560	COG1176	ABC-type spermidine putrescine transport system, permease component I
KAM329_043570	COG3842	ATPase activity
KAM329_043610	COG0174	glutamine synthetase
KAM329_043650	COG3045	CreA protein
KAM329_043660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KAM329_043670	COG0443	Heat shock 70 kDa protein
KAM329_043700	COG0366	Alpha amylase catalytic
KAM329_043730	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KAM329_043740	COG0745	RESPONSE REGULATOR receiver
KAM329_043750	COG2205	protein histidine kinase activity
KAM329_043770	COG0281	malic enzyme
KAM329_043780	COG0702	epimerase
KAM329_043790	COG0254	rRNA binding
KAM329_043800	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KAM329_043850	COG0129	dihydroxy-acid dehydratase activity
KAM329_043870	COG3978	acetolactate synthase activity
KAM329_043890	COG0606	chelatase, subunit chli
KAM329_043900	COG0204	Acyl-transferase
KAM329_043910	COG0204	Acyl-transferase
KAM329_043920	COG1683	Conserved Protein
KAM329_043940	COG1335	isochorismatase
KAM329_043960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KAM329_043970	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KAM329_043990	COG3084	Protein conserved in bacteria
KAM329_044000	COG4251	negative regulation of phosphorylation
KAM329_044000	COG3706	GGDEF domain
KAM329_044000	COG5001	Diguanylate cyclase
KAM329_044000	COG2203	Gaf domain
KAM329_044030	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KAM329_044040	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KAM329_044050	COG1561	YicC-like family, N-terminal region
KAM329_044070	COG1519	Transferase
KAM329_044080	COG0859	PFAM glycosyl transferase family 9
KAM329_044100	COG0463	Glycosyl transferase, family 2
KAM329_044110	COG0859	PFAM glycosyl transferase family 9
KAM329_044120	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KAM329_044130	COG2990	Protein conserved in bacteria
KAM329_044140	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KAM329_044160	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KAM329_044170	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KAM329_044180	COG2003	Belongs to the UPF0758 family
KAM329_044190	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KAM329_044200	COG0756	dUTP diphosphatase activity
KAM329_044210	COG1309	transcriptional regulator
KAM329_044220	COG0668	transmembrane transport
KAM329_044240	COG0166	Belongs to the GPI family
KAM329_044250	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KAM329_044260	COG0583	DNA-binding transcription factor activity
KAM329_044280	COG0045	succinate-CoA ligase (ADP-forming) activity
KAM329_044280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KAM329_044280	COG1042	CoA-binding domain protein
KAM329_044290	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
KAM329_044300	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KAM329_044310	COG1739	Uncharacterized protein family UPF0029
KAM329_044320	COG0006	proline dipeptidase activity
KAM329_044330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KAM329_044340	COG1024	Enoyl-CoA hydratase
KAM329_044340	COG1250	3-hydroxyacyl-CoA dehydrogenase
KAM329_044350	COG0183	Belongs to the thiolase family
KAM329_044400	COG0425	Belongs to the sulfur carrier protein TusA family
KAM329_044410	COG0251	oxidation-reduction process
KAM329_044420	COG2885	chlorophyll binding
KAM329_044450	COG1335	isochorismatase
KAM329_044460	COG2818	Glycosylase
KAM329_044470	COG0752	glycyl-tRNA synthetase alpha subunit
KAM329_044480	COG0751	glycine-tRNA ligase activity
KAM329_044510	COG2203	Gaf domain
KAM329_044510	COG3706	GGDEF domain
KAM329_044510	COG4251	negative regulation of phosphorylation
KAM329_044510	COG5001	Diguanylate cyclase
KAM329_044550	COG0814	amino acid
KAM329_044560	COG0814	amino acid
KAM329_044570	COG3033	Beta-eliminating lyase
KAM329_044580	COG0348	domain, Protein
KAM329_044600	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAM329_044610	COG1773	rubredoxin
KAM329_044610	COG0426	domain, Protein
KAM329_044620	COG3604	Transcriptional regulator
KAM329_044630	COG1609	Transcriptional regulator
KAM329_044710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KAM329_044740	COG2960	long-chain fatty acid transporting porin activity
KAM329_044760	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KAM329_044790	COG3118	belongs to the thioredoxin family
KAM329_044800	COG0513	Belongs to the DEAD box helicase family
KAM329_044810	COG0248	Ppx GppA phosphatase
KAM329_044830	COG0742	ribosomal rna small subunit methyltransferase
KAM329_044870	COG0084	hydrolase, TatD family'
KAM329_044880	COG0805	protein transport
KAM329_044890	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KAM329_044900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KAM329_044910	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KAM329_044920	COG3165	ubiquinone biosynthetic process from chorismate
KAM329_044940	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KAM329_044950	COG0402	S-adenosylhomocysteine deaminase activity
KAM329_044970	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KAM329_044980	COG0848	biopolymer transport protein
KAM329_044990	COG0811	peptide transport
KAM329_045000	COG0811	peptide transport
KAM329_045020	COG2771	luxR family
KAM329_045110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KAM329_045120	COG0443	Heat shock 70 kDa protein
KAM329_045190	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KAM329_045200	COG1349	DNA-binding transcription factor activity
KAM329_045210	COG0745	RESPONSE REGULATOR receiver
KAM329_045220	COG2205	protein histidine kinase activity
KAM329_045240	COG4452	Inner membrane protein CreD
KAM329_045250	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KAM329_045260	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KAM329_045270	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KAM329_045280	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KAM329_045290	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KAM329_045300	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KAM329_045310	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KAM329_045330	COG0356	it plays a direct role in the translocation of protons across the membrane
KAM329_045350	COG1475	DNA binding
KAM329_045360	COG1192	Involved in chromosome partitioning
KAM329_045370	COG0357	Ribosomal RNA small subunit methyltransferase G
KAM329_045380	COG0445	tRNA wobble uridine modification
KAM329_045390	COG0716	FMN binding
KAM329_045400	COG4774	siderophore transport
KAM329_045410	COG4615	Cyclic peptide transporter
KAM329_045420	COG1120	ATPase activity
KAM329_045430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KAM329_045450	COG3550	peptidyl-serine autophosphorylation
KAM329_045490	COG2801	Transposase and inactivated derivatives
KAM329_045510	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KAM329_045520	COG0706	membrane insertase activity
KAM329_045530	COG0594	ribonuclease P activity
KAM329_045540	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KAM329_045550	COG1126	abc transporter atp-binding protein
KAM329_45690	COG1192	Involved in chromosome partitioning
KAM329_45770	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KAM329_45880	COG0419	ATPase involved in DNA repair
KAM329_45930	COG3550	peptidyl-serine autophosphorylation
KAM329_46120	COG0776	regulation of translation
KAM329_46160	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KAM329_46320	COG1192	Involved in chromosome partitioning
KAM329_46380	COG0358	DNA primase activity
KAM329_46420	COG1923	regulation of RNA biosynthetic process
KAM329_46480	COG5301	cellulose 1,4-beta-cellobiosidase activity
KAM329_46780	COG0556	nucleotide-excision repair
KAM329_46860	COG3039	Transposase
KAM329_46890	COG4974	Belongs to the 'phage' integrase family
KAM329_47230	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KAM329_47260	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM329_47350	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM329_47470	COG2948	multi-organism process
KAM329_47490	COG3504	Conjugal transfer protein
KAM329_47510	COG3451	type IV secretory pathway VirB4
KAM329_47530	COG3838	Conjugal transfer protein Trbc
KAM329_47540	COG4962	Type ii secretion system protein e
KAM329_47560	COG3041	Addiction module toxin RelE StbE family
KAM329_47570	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM329_47600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM329_47660	COG1192	Involved in chromosome partitioning
KAM329_47730	COG1192	Involved in chromosome partitioning
KAM329_47810	COG5002	protein histidine kinase activity
KAM329_47810	COG2176	DNA-directed DNA polymerase activity