locus-tag	class	description
KAM339_000010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KAM339_000020	COG0592	DNA-directed DNA polymerase activity
KAM339_000050	COG2207	Transcriptional regulator
KAM339_000060	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KAM339_000070	COG0071	Belongs to the small heat shock protein (HSP20) family
KAM339_000080	COG0071	Belongs to the small heat shock protein (HSP20) family
KAM339_000090	COG3977	Valine--pyruvate aminotransferase
KAM339_000120	COG2814	Major facilitator Superfamily
KAM339_000130	COG0745	RESPONSE REGULATOR receiver
KAM339_000140	COG2205	protein histidine kinase activity
KAM339_000180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KAM339_000190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM339_000190	COG4191	Histidine kinase
KAM339_000200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM339_000210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM339_000250	COG0561	phosphatase activity
KAM339_000260	COG2267	carboxylic ester hydrolase activity
KAM339_000270	COG0110	maltose O-acetyltransferase activity
KAM339_000280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KAM339_000290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KAM339_000300	COG1758	RNA polymerase activity
KAM339_000320	COG0859	PFAM glycosyl transferase family 9
KAM339_000330	COG3642	lipopolysaccharide core region biosynthetic process
KAM339_000410	COG0589	response to stress
KAM339_000420	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KAM339_000430	COG3706	GGDEF domain
KAM339_000440	COG1528	Iron-storage protein
KAM339_000450	COG2081	HI0933 family
KAM339_000460	COG2223	nitrite transmembrane transporter activity
KAM339_000470	COG1280	lysine exporter protein (LysE YggA)
KAM339_000520	COG3188	usher protein
KAM339_000550	COG2197	response regulator
KAM339_000560	COG2205	protein histidine kinase activity
KAM339_000560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM339_000580	COG3275	phosphorelay sensor kinase activity
KAM339_000590	COG3279	Response regulator of the LytR AlgR family
KAM339_000600	COG2223	nitrite transmembrane transporter activity
KAM339_000610	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KAM339_000620	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KAM339_000670	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KAM339_000680	COG2166	iron-sulfur cluster assembly
KAM339_000690	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KAM339_000700	COG0210	DNA helicase
KAM339_000730	COG1063	alcohol dehydrogenase
KAM339_000740	COG0156	8-amino-7-oxononanoate synthase activity
KAM339_000760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KAM339_000850	COG1609	Transcriptional regulator
KAM339_000890	COG1580	Controls the rotational direction of flagella during chemotaxis
KAM339_000900	COG3161	chorismate lyase activity
KAM339_000910	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KAM339_000920	COG2937	Belongs to the GPAT DAPAT family
KAM339_000930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KAM339_000960	COG0534	Mate efflux family protein
KAM339_000970	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KAM339_000980	COG2205	protein histidine kinase activity
KAM339_000990	COG0745	RESPONSE REGULATOR receiver
KAM339_001010	COG1045	serine acetyltransferase
KAM339_001030	COG3074	FtsZ-dependent cytokinesis
KAM339_001040	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
KAM339_001050	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KAM339_001050	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KAM339_001060	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KAM339_001070	COG1609	Transcriptional regulator
KAM339_001080	COG3250	beta-galactosidase activity
KAM339_001090	COG2731	YhcH YjgK YiaL family protein
KAM339_001100	COG0531	amino acid
KAM339_001110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM339_001120	COG0531	amino acid
KAM339_001130	COG0385	Bile acid
KAM339_001140	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KAM339_001190	COG0583	DNA-binding transcription factor activity
KAM339_001200	COG1079	Belongs to the binding-protein-dependent transport system permease family
KAM339_001210	COG4603	Belongs to the binding-protein-dependent transport system permease family
KAM339_001220	COG3845	ABC transporter
KAM339_001230	COG1744	ABC transporter substrate-binding protein PnrA-like
KAM339_001240	COG0210	DNA helicase
KAM339_001250	COG2131	deaminase
KAM339_001280	COG1943	Transposase
KAM339_001290	COG0583	DNA-binding transcription factor activity
KAM339_001370	COG1280	lysine exporter protein (LysE YggA)
KAM339_001390	COG2962	Rard protein
KAM339_001410	COG1012	belongs to the aldehyde dehydrogenase family
KAM339_001430	COG1396	sequence-specific DNA binding
KAM339_001440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KAM339_001460	COG0519	Catalyzes the synthesis of GMP from XMP
KAM339_001460	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KAM339_001480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM339_001520	COG1322	Protein conserved in bacteria
KAM339_001530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KAM339_001540	COG0569	domain protein
KAM339_001550	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KAM339_001550	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KAM339_001560	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KAM339_001570	COG0242	peptide deformylase activity
KAM339_001590	COG0758	DNA mediated transformation
KAM339_001600	COG2922	Belongs to the Smg family
KAM339_001610	COG0551	DNA topoisomerase type I activity
KAM339_001620	COG0009	L-threonylcarbamoyladenylate synthase
KAM339_001630	COG0408	coproporphyrinogen oxidase activity
KAM339_001640	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KAM339_001650	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KAM339_001670	COG3078	GTPase activator activity
KAM339_001690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KAM339_001700	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KAM339_001720	COG3852	Histidine kinase
KAM339_001740	COG0174	glutamine synthetase
KAM339_001750	COG1217	gtp-binding protein TYPA
KAM339_001760	COG1295	ribonuclease BN
KAM339_001770	COG1490	D-aminoacyl-tRNA deacylase activity
KAM339_001800	COG0456	acetyltransferase
KAM339_001820	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KAM339_001830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KAM339_001840	COG2610	gluconate transmembrane transporter activity
KAM339_001850	COG3265	gluconokinase activity
KAM339_001860	COG0129	dihydroxy-acid dehydratase activity
KAM339_001870	COG0800	Aldolase
KAM339_001900	COG1609	Transcriptional regulator
KAM339_001920	COG4942	peptidase
KAM339_001930	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KAM339_001940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KAM339_001950	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KAM339_001960	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KAM339_001970	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KAM339_001970	COG0316	Belongs to the HesB IscA family
KAM339_001980	COG1040	competence protein
KAM339_001990	COG0596	Alpha beta hydrolase
KAM339_002020	COG2183	response to ionizing radiation
KAM339_002030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KAM339_002050	COG2205	protein histidine kinase activity
KAM339_002070	COG0051	transcription antitermination factor activity, RNA binding
KAM339_002080	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KAM339_002090	COG0088	Forms part of the polypeptide exit tunnel
KAM339_002100	COG0089	rRNA binding
KAM339_002110	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KAM339_002120	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KAM339_002130	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KAM339_002140	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KAM339_002150	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KAM339_002160	COG0255	Belongs to the universal ribosomal protein uL29 family
KAM339_002170	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KAM339_002180	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KAM339_002190	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KAM339_002200	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KAM339_002210	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KAM339_002220	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KAM339_002230	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KAM339_002240	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KAM339_002250	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KAM339_002260	COG1841	ribosomal large subunit assembly
KAM339_002270	COG0200	Binds to the 23S rRNA
KAM339_002280	COG0201	protein transport
KAM339_002290	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KAM339_002300	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KAM339_002310	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KAM339_002320	COG0202	RNA polymerase activity
KAM339_002330	COG0203	ribosomal protein L17
KAM339_002350	COG2963	transposase activity
KAM339_002360	COG2826	transposase and inactivated derivatives, IS30 family
KAM339_002370	COG2801	Transposase and inactivated derivatives
KAM339_002420	COG2249	NAD(P)H dehydrogenase (quinone) activity
KAM339_002430	COG0583	DNA-binding transcription factor activity
KAM339_002440	COG4221	oxidoreductase activity
KAM339_002470	COG1770	oligopeptidase
KAM339_002480	COG2358	TRAP transporter, solute receptor (TAXI family
KAM339_002510	COG3714	YhhN family
KAM339_002540	COG0583	DNA-binding transcription factor activity
KAM339_002560	COG1301	dicarboxylic acid transport
KAM339_002580	COG2095	MarC family integral membrane protein
KAM339_002600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KAM339_002620	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KAM339_002640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KAM339_002700	COG0742	ribosomal rna small subunit methyltransferase
KAM339_002720	COG0552	protein localization to endoplasmic reticulum
KAM339_002730	COG2884	Cell division ATP-binding protein ftsE
KAM339_002740	COG2177	Part of the ABC transporter FtsEX involved in
KAM339_002760	COG0288	reversible hydration of carbon dioxide
KAM339_002770	COG2188	Transcriptional regulator
KAM339_002780	COG1228	amidohydrolase
KAM339_002790	COG0010	Belongs to the arginase family
KAM339_002800	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KAM339_002810	COG2986	histidine ammonia-lyase
KAM339_002820	COG0387	Pfam Sodium calcium exchanger
KAM339_002830	COG2200	EAL domain
KAM339_002940	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KAM339_002950	COG1459	type II secretion system
KAM339_002970	COG2165	general secretion pathway protein
KAM339_003040	COG1077	Cell shape determining protein MreB Mrl
KAM339_003050	COG1792	Involved in formation and maintenance of cell shape
KAM339_003060	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KAM339_003070	COG0424	maF-like protein
KAM339_003080	COG1530	ribonuclease E activity
KAM339_003090	COG3164	Protein of unknown function
KAM339_003100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KAM339_003110	COG0312	modulator of DNA gyrase
KAM339_003140	COG0477	Major facilitator Superfamily
KAM339_003160	COG2321	neutral zinc metallopeptidase
KAM339_003240	COG0189	ligase activity
KAM339_003250	COG0642	Histidine kinase
KAM339_003260	COG0745	RESPONSE REGULATOR receiver
KAM339_003290	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KAM339_003300	COG0352	thiamine-phosphate diphosphorylase activity
KAM339_003310	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KAM339_003330	COG2022	thiamine diphosphate biosynthetic process
KAM339_003340	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KAM339_003350	COG2801	Transposase and inactivated derivatives
KAM339_003430	COG3932	Exopolysaccharide synthesis, ExoD
KAM339_003460	COG1733	regulation of RNA biosynthetic process
KAM339_003530	COG2226	methyltransferase
KAM339_003550	COG1494	fructose-1,6-bisphosphatase
KAM339_003570	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KAM339_003580	COG5007	Belongs to the BolA IbaG family
KAM339_003600	COG2854	intermembrane phospholipid transfer
KAM339_003610	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KAM339_003620	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KAM339_003630	COG1127	ABC transporter
KAM339_003640	COG0517	IMP dehydrogenase activity
KAM339_003640	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KAM339_003650	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KAM339_003670	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KAM339_003680	COG1137	ATPase activity
KAM339_003690	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KAM339_003710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM339_003720	COG1660	Displays ATPase and GTPase activities
KAM339_003730	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM339_003770	COG3964	amidohydrolase
KAM339_003830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KAM339_003840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KAM339_003860	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KAM339_003870	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KAM339_003880	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KAM339_003890	COG0723	plastoquinol--plastocyanin reductase activity
KAM339_003900	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KAM339_003910	COG2857	Cytochrome c1
KAM339_003920	COG0625	glutathione transferase activity
KAM339_003930	COG2969	positive regulation of protein catabolic process
KAM339_003940	COG2823	Periplasmic or secreted lipoprotein
KAM339_003950	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KAM339_003960	COG0792	nuclease activity
KAM339_003970	COG3107	peptidoglycan biosynthetic process
KAM339_003980	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KAM339_003990	COG2001	Belongs to the MraZ family
KAM339_004000	COG0275	rRNA processing
KAM339_004010	COG3116	cell division
KAM339_004020	COG0768	penicillin binding
KAM339_004030	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KAM339_004040	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KAM339_004050	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KAM339_004060	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KAM339_004070	COG0772	Belongs to the SEDS family
KAM339_004080	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KAM339_004090	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KAM339_004100	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KAM339_004110	COG0849	cell division
KAM339_004120	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KAM339_004130	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KAM339_004150	COG0653	protein targeting
KAM339_004170	COG0494	nUDIX hydrolase
KAM339_004180	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KAM339_004190	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
KAM339_004210	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KAM339_004220	COG1459	type II secretion system
KAM339_004230	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KAM339_004280	COG2186	Transcriptional regulator
KAM339_004290	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KAM339_004300	COG0508	dehydrogenase complex catalyzes the overall conversion of
KAM339_004310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KAM339_004330	COG0840	transmembrane signaling receptor activity
KAM339_004340	COG0840	transmembrane signaling receptor activity
KAM339_004350	COG1752	Esterase of the alpha-beta hydrolase superfamily
KAM339_004360	COG1049	propionate catabolic process, 2-methylcitrate cycle
KAM339_004370	COG2200	EAL domain
KAM339_004390	COG1280	lysine exporter protein (LysE YggA)
KAM339_004410	COG0523	cobalamin synthesis protein
KAM339_004420	COG0477	Major facilitator Superfamily
KAM339_004450	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KAM339_004460	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KAM339_004510	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KAM339_004530	COG1546	Belongs to the CinA family
KAM339_004540	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KAM339_004550	COG2137	regulation of response to DNA damage stimulus
KAM339_004560	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KAM339_004570	COG0527	aspartate kinase activity
KAM339_004580	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KAM339_004590	COG1686	Belongs to the peptidase S11 family
KAM339_004600	COG0586	Pfam SNARE associated Golgi protein
KAM339_004610	COG1253	flavin adenine dinucleotide binding
KAM339_004620	COG0525	valine-tRNA ligase activity
KAM339_004630	COG2927	DNA polymerase III (CHI subunit)
KAM339_004640	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KAM339_004650	COG0795	lipopolysaccharide-transporting ATPase activity
KAM339_004660	COG0795	lipopolysaccharide-transporting ATPase activity
KAM339_004700	COG3646	Phage regulatory protein
KAM339_004940	COG4695	Portal protein
KAM339_005180	COG4974	Belongs to the 'phage' integrase family
KAM339_005200	COG0004	ammonium transporteR
KAM339_005210	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KAM339_005240	COG2165	general secretion pathway protein
KAM339_005250	COG0084	hydrolase, TatD family'
KAM339_005260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KAM339_005280	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KAM339_005290	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KAM339_005300	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KAM339_005320	COG4520	surface antigen
KAM339_005330	COG3447	MASE1 domain protein
KAM339_005330	COG5002	protein histidine kinase activity
KAM339_005330	COG5001	Diguanylate cyclase
KAM339_005350	COG0560	Phosphoserine phosphatase
KAM339_005380	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KAM339_005400	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
KAM339_005410	COG0776	regulation of translation
KAM339_005440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KAM339_005450	COG0735	belongs to the Fur family
KAM339_005490	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KAM339_005500	COG0513	Belongs to the DEAD box helicase family
KAM339_005510	COG3022	response to hydroperoxide
KAM339_005540	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KAM339_005550	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KAM339_005560	COG0762	integral membrane protein
KAM339_005570	COG1872	DUF167
KAM339_005610	COG3112	Uncharacterised protein family (UPF0231)
KAM339_005620	COG3835	regulator
KAM339_005630	COG2610	gluconate transmembrane transporter activity
KAM339_005640	COG1929	Belongs to the glycerate kinase type-1 family
KAM339_005670	COG0583	DNA-binding transcription factor activity
KAM339_005680	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KAM339_005710	COG0347	Belongs to the P(II) protein family
KAM339_005740	COG3842	ATPase activity
KAM339_005750	COG2837	iron assimilation
KAM339_005760	COG1438	arginine binding
KAM339_005770	COG1126	abc transporter atp-binding protein
KAM339_005780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM339_005790	COG4215	(ABC) transporter
KAM339_005800	COG4160	amino acid transport
KAM339_005810	COG0039	L-malate dehydrogenase activity
KAM339_005830	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
KAM339_005840	COG1017	nitric oxide dioxygenase activity
KAM339_005840	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KAM339_005860	COG4536	flavin adenine dinucleotide binding
KAM339_005870	COG4137	Cytochrome C assembly protein
KAM339_005880	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KAM339_005890	COG0228	four-way junction DNA binding
KAM339_005900	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KAM339_005910	COG0336	Belongs to the RNA methyltransferase TrmD family
KAM339_005920	COG0335	large ribosomal subunit rRNA binding
KAM339_005950	COG1051	belongs to the nudix hydrolase family
KAM339_005970	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KAM339_005980	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KAM339_005990	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KAM339_006270	COG4695	Portal protein
KAM339_006290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KAM339_006500	COG4974	Belongs to the 'phage' integrase family
KAM339_006510	COG0583	DNA-binding transcription factor activity
KAM339_006520	COG0640	Transcriptional regulator
KAM339_006530	COG0268	Binds directly to 16S ribosomal RNA
KAM339_006540	COG0728	peptidoglycan biosynthetic process
KAM339_006550	COG0196	riboflavin kinase activity
KAM339_006560	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KAM339_006570	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KAM339_006580	COG1047	Peptidyl-prolyl cis-trans
KAM339_006590	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KAM339_006670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KAM339_006670	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KAM339_006700	COG1854	S-ribosylhomocysteine lyase activity
KAM339_006710	COG3706	GGDEF domain
KAM339_006720	COG0557	exoribonuclease II activity
KAM339_006730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KAM339_006750	COG2153	protein acetylation
KAM339_006770	COG1914	H( )-stimulated, divalent metal cation uptake system
KAM339_006780	COG0360	Binds together with S18 to 16S ribosomal RNA
KAM339_006790	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KAM339_006800	COG0359	binds to the 23S rRNA
KAM339_006880	COG1238	metal cluster binding
KAM339_006890	COG0612	Peptidase, M16
KAM339_006900	COG2918	glutathione biosynthetic process
KAM339_006910	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KAM339_006920	COG1027	Aspartate ammonia-lyase
KAM339_006930	COG3030	protein affecting phage T7 exclusion by the F plasmid
KAM339_006940	COG0534	Mate efflux family protein
KAM339_006950	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KAM339_006960	COG0459	protein refolding
KAM339_007010	COG0564	pseudouridine synthase activity
KAM339_007020	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KAM339_007030	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KAM339_007050	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KAM339_007060	COG4208	sulfate ABC transporter
KAM339_007070	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KAM339_007080	COG0583	DNA-binding transcription factor activity
KAM339_007090	COG3397	chitin binding
KAM339_007100	COG0840	transmembrane signaling receptor activity
KAM339_007150	COG1328	CTP reductase activity
KAM339_007160	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KAM339_007190	COG1448	Aminotransferase
KAM339_007200	COG2194	sulfuric ester hydrolase activity
KAM339_007230	COG1215	transferase activity, transferring glycosyl groups
KAM339_007250	COG1215	transferase activity, transferring glycosyl groups
KAM339_007260	COG1215	transferase activity, transferring glycosyl groups
KAM339_007280	COG3118	belongs to the thioredoxin family
KAM339_007280	COG0457	Tetratricopeptide repeat
KAM339_007340	COG2948	multi-organism process
KAM339_007370	COG3846	protein secretion by the type IV secretion system
KAM339_007400	COG3451	type IV secretory pathway VirB4
KAM339_007420	COG3838	Conjugal transfer protein Trbc
KAM339_007430	COG4962	Type ii secretion system protein e
KAM339_007470	COG0583	DNA-binding transcription factor activity
KAM339_007520	COG2076	Multidrug Resistance protein
KAM339_007560	COG4959	Type IV secretory pathway protease TraF
KAM339_007590	COG1192	Involved in chromosome partitioning
KAM339_007650	COG5489	Protein of unknown function (DUF736)
KAM339_007710	COG2003	Belongs to the UPF0758 family
KAM339_007860	COG0513	Belongs to the DEAD box helicase family
KAM339_007890	COG4166	transmembrane transport
KAM339_007920	COG1024	Enoyl-CoA hydratase
KAM339_007950	COG4221	oxidoreductase activity
KAM339_007960	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KAM339_007970	COG0442	prolyl-tRNA aminoacylation
KAM339_007980	COG0840	transmembrane signaling receptor activity
KAM339_007990	COG0632	four-way junction helicase activity
KAM339_008000	COG2255	four-way junction helicase activity
KAM339_008010	COG1271	oxidase subunit
KAM339_008020	COG1294	oxidase, subunit
KAM339_008030	COG3790	cyd operon protein YbgE
KAM339_008040	COG0824	Thioesterase
KAM339_008050	COG0811	peptide transport
KAM339_008080	COG0823	Involved in the tonB-independent uptake of proteins
KAM339_008090	COG2885	chlorophyll binding
KAM339_008100	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
KAM339_008110	COG0840	transmembrane signaling receptor activity
KAM339_008120	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KAM339_008140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KAM339_008150	COG1640	4-alpha-glucanotransferase
KAM339_008160	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KAM339_008220	COG2130	NADP-dependent
KAM339_008230	COG1846	Transcriptional regulator
KAM339_008290	COG0561	phosphatase activity
KAM339_008320	COG0733	neurotransmitter:sodium symporter activity
KAM339_008330	COG0733	neurotransmitter:sodium symporter activity
KAM339_008360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KAM339_008390	COG1794	racemase activity, acting on amino acids and derivatives
KAM339_008410	COG1022	Amp-dependent synthetase and ligase
KAM339_008430	COG0456	acetyltransferase
KAM339_008460	COG2425	protein containing a von Willebrand factor type A (vWA) domain
KAM339_008470	COG5002	protein histidine kinase activity
KAM339_008470	COG5001	Diguanylate cyclase
KAM339_008520	COG0456	acetyltransferase
KAM339_008530	COG1902	pentaerythritol trinitrate reductase activity
KAM339_008560	COG2957	Belongs to the agmatine deiminase family
KAM339_008570	COG0154	amidase activity
KAM339_008580	COG2801	Transposase and inactivated derivatives
KAM339_008670	COG0513	Belongs to the DEAD box helicase family
KAM339_008680	COG2203	Gaf domain
KAM339_008680	COG2199	diguanylate cyclase activity
KAM339_008750	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
KAM339_008770	COG1136	(ABC) transporter
KAM339_008770	COG0577	efflux transmembrane transporter activity
KAM339_008780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM339_008790	COG0745	RESPONSE REGULATOR receiver
KAM339_008800	COG2205	protein histidine kinase activity
KAM339_008870	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KAM339_008890	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KAM339_008900	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
KAM339_008910	COG1178	ABC-type Fe3 transport system permease component
KAM339_008920	COG4143	(ABC) transporter
KAM339_008950	COG0066	3-isopropylmalate dehydratase activity
KAM339_008960	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KAM339_008970	COG0473	3-isopropylmalate dehydrogenase activity
KAM339_008980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KAM339_009000	COG0671	phosphoesterase, PA-phosphatase related
KAM339_009030	COG0028	Belongs to the TPP enzyme family
KAM339_009040	COG0440	acetolactate synthase activity
KAM339_009050	COG0857	belongs to the CobB CobQ family
KAM339_009050	COG0280	phosphate acetyltransferase
KAM339_009060	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KAM339_009070	COG3092	negative regulation of chromosome organization
KAM339_009080	COG3013	Belongs to the UPF0304 family
KAM339_009090	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KAM339_009100	COG2716	regulation of RNA biosynthetic process
KAM339_009110	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KAM339_009120	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
KAM339_009130	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KAM339_009160	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
KAM339_009200	COG0784	Response regulator, receiver
KAM339_009200	COG5002	protein histidine kinase activity
KAM339_009200	COG2198	Histidine kinase
KAM339_009230	COG0784	Response regulator, receiver
KAM339_009230	COG2205	protein histidine kinase activity
KAM339_009270	COG1464	Belongs to the NlpA lipoprotein family
KAM339_009280	COG2011	ABC-type metal ion transport system permease component
KAM339_009290	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KAM339_009330	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KAM339_009330	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KAM339_009340	COG0802	atpase or kinase
KAM339_009360	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KAM339_009370	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KAM339_009380	COG1923	regulation of RNA biosynthetic process
KAM339_009390	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KAM339_009400	COG0330	HflC and HflK could
KAM339_009410	COG0330	HflC and HflK could
KAM339_009430	COG0142	geranyltranstransferase activity
KAM339_009440	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KAM339_009450	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KAM339_009460	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KAM339_009470	COG3314	Sporulation integral membrane protein YlbJ
KAM339_009480	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KAM339_009490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KAM339_009510	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KAM339_009520	COG2967	ApaG domain
KAM339_009530	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KAM339_009540	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KAM339_009560	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KAM339_009570	COG3178	'Phosphotransferase
KAM339_009580	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KAM339_009590	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KAM339_009600	COG2252	PERMEase
KAM339_009620	COG0488	(ABC) transporter
KAM339_009630	COG0741	lytic transglycosylase activity
KAM339_009640	COG0463	Glycosyl transferase, family 2
KAM339_009660	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KAM339_009720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAM339_009740	COG3721	Heme iron utilization protein
KAM339_009750	COG0748	coenzyme F420 binding
KAM339_009800	COG2814	Major facilitator Superfamily
KAM339_009810	COG2205	protein histidine kinase activity
KAM339_009810	COG2202	Pas domain
KAM339_009830	COG2226	methyltransferase
KAM339_009850	COG1765	OsmC-like protein
KAM339_009880	COG3954	Phosphoribulokinase
KAM339_009890	COG3089	Belongs to the UPF0270 family
KAM339_009900	COG5001	Diguanylate cyclase
KAM339_009900	COG2203	Gaf domain
KAM339_009900	COG3706	GGDEF domain
KAM339_009900	COG4251	negative regulation of phosphorylation
KAM339_009910	COG0429	hydrolase of the alpha beta-hydrolase fold
KAM339_009920	COG0784	Response regulator, receiver
KAM339_009920	COG0835	chemotaxis
KAM339_009940	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KAM339_009950	COG1047	Peptidyl-prolyl cis-trans
KAM339_009960	COG2900	Belongs to the SlyX family
KAM339_009980	COG0545	Peptidyl-prolyl cis-trans isomerase
KAM339_009990	COG2204	response regulator
KAM339_010030	COG0737	Belongs to the 5'-nucleotidase family
KAM339_010060	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KAM339_010070	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KAM339_010070	COG0506	proline dehydrogenase activity
KAM339_010070	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KAM339_010090	COG0114	fumarate hydratase activity
KAM339_010110	COG1566	PFAM secretion protein HlyD family protein
KAM339_010220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KAM339_010240	COG1280	lysine exporter protein (LysE YggA)
KAM339_010250	COG0826	peptidase U32
KAM339_010270	COG3813	Protein conserved in bacteria
KAM339_010310	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KAM339_010360	COG0300	oxidoreductase activity
KAM339_010400	COG2610	gluconate transmembrane transporter activity
KAM339_010410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KAM339_010420	COG3622	Belongs to the hyi family
KAM339_010430	COG0235	Class ii aldolase
KAM339_010450	COG2084	Dehydrogenase
KAM339_010460	COG1349	DNA-binding transcription factor activity
KAM339_010480	COG2133	pyrroloquinoline quinone binding
KAM339_010530	COG1605	Chorismate mutase
KAM339_010530	COG0077	Prephenate dehydratase
KAM339_010580	COG3272	Protein of unknown function (DUF1722)
KAM339_010590	COG0789	Transcriptional regulator
KAM339_010600	COG0415	Belongs to the DNA photolyase family
KAM339_010620	COG4221	oxidoreductase activity
KAM339_010650	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KAM339_010700	COG0783	Belongs to the Dps family
KAM339_010710	COG1151	hydroxylamine reductase activity
KAM339_010730	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KAM339_010750	COG1737	Transcriptional regulator
KAM339_010810	COG3385	transposase activity
KAM339_010840	COG3039	Transposase
KAM339_010910	COG1160	GTP binding
KAM339_010970	COG0582	viral genome integration into host DNA
KAM339_010990	COG1447	Phosphotransferase system cellobiose-specific component IIA
KAM339_011000	COG2723	6-phospho-beta-galactosidase activity
KAM339_011020	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KAM339_011030	COG5297	Belongs to the glycosyl hydrolase family 6
KAM339_011030	COG2273	Hydrolase Family 16
KAM339_011040	COG1472	Belongs to the glycosyl hydrolase 3 family
KAM339_011060	COG2182	Extracellular solute-binding protein
KAM339_011070	COG1609	Transcriptional regulator
KAM339_011120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM339_011130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM339_011140	COG0745	RESPONSE REGULATOR receiver
KAM339_011150	COG5000	phosphorelay sensor kinase activity
KAM339_011150	COG5002	protein histidine kinase activity
KAM339_011160	COG0659	secondary active sulfate transmembrane transporter activity
KAM339_011170	COG0659	secondary active sulfate transmembrane transporter activity
KAM339_011190	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KAM339_011200	COG1666	GTP binding
KAM339_011220	COG2211	Major facilitator Superfamily
KAM339_011240	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KAM339_011260	COG2813	Specifically methylates the guanine in position
KAM339_011270	COG0271	Belongs to the BolA IbaG family
KAM339_011280	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM339_011290	COG1805	sodium ion transport
KAM339_011300	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM339_011310	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM339_011320	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM339_011330	COG2871	sodium ion transport
KAM339_011340	COG1477	protein flavinylation
KAM339_011370	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KAM339_011380	COG0840	transmembrane signaling receptor activity
KAM339_011390	COG0583	DNA-binding transcription factor activity
KAM339_011420	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
KAM339_011440	COG0473	3-isopropylmalate dehydrogenase activity
KAM339_011450	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KAM339_011470	COG1611	Belongs to the LOG family
KAM339_011500	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KAM339_011500	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KAM339_011570	COG1484	DNA-dependent DNA replication
KAM339_011580	COG4584	PFAM Integrase catalytic
KAM339_011700	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM339_011760	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
KAM339_011810	COG3098	single-species biofilm formation
KAM339_011820	COG0564	pseudouridine synthase activity
KAM339_011840	COG4580	involved in the transport of maltose and maltodextrins
KAM339_011860	COG1263	PTS System
KAM339_011860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM339_011880	COG2171	N-acyltransferase activity
KAM339_011890	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KAM339_011900	COG0024	Methionine aminopeptidase
KAM339_011910	COG0052	Belongs to the universal ribosomal protein uS2 family
KAM339_011920	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KAM339_011930	COG0528	UMP kinase activity
KAM339_011940	COG0233	cytoplasmic translational termination
KAM339_011950	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KAM339_011960	COG0575	Belongs to the CDS family
KAM339_011970	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KAM339_011980	COG0750	zinc metalloprotease
KAM339_012010	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAM339_012020	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KAM339_012030	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAM339_012040	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAM339_012050	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KAM339_012070	COG0825	malonyl-CoA metabolic process
KAM339_012100	COG0814	amino acid
KAM339_012110	COG0531	amino acid
KAM339_012130	COG0488	(ABC) transporter
KAM339_012150	COG3590	peptidase
KAM339_012160	COG0037	tRNA processing
KAM339_012170	COG3706	GGDEF domain
KAM339_012240	COG0366	Alpha amylase catalytic
KAM339_012270	COG0463	Glycosyl transferase, family 2
KAM339_012300	COG2989	Protein conserved in bacteria
KAM339_012310	COG3108	Peptidase M15
KAM339_012330	COG2860	membrane
KAM339_012350	COG1196	nuclear chromosome segregation
KAM339_012360	COG3115	cell septum assembly
KAM339_012370	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KAM339_012390	COG1328	CTP reductase activity
KAM339_012410	COG0602	queuosine metabolic process
KAM339_012460	COG1566	PFAM secretion protein HlyD family protein
KAM339_012480	COG3290	protein histidine kinase activity
KAM339_012510	COG0667	Aldo Keto reductase
KAM339_012520	COG0697	spore germination
KAM339_012550	COG3284	Transcriptional regulator
KAM339_012560	COG3706	GGDEF domain
KAM339_012570	COG0346	lactoylglutathione lyase activity
KAM339_012580	COG0745	RESPONSE REGULATOR receiver
KAM339_012590	COG5002	protein histidine kinase activity
KAM339_012610	COG4783	chaperone-mediated protein folding
KAM339_012630	COG1940	carbohydrate kinase activity
KAM339_012650	COG0545	Peptidyl-prolyl cis-trans isomerase
KAM339_012660	COG1131	(ABC) transporter
KAM339_012690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM339_012700	COG4597	amino acid ABC transporter
KAM339_012710	COG0765	amino acid transport
KAM339_012720	COG1126	abc transporter atp-binding protein
KAM339_012740	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KAM339_012750	COG0678	peroxiredoxin activity
KAM339_012770	COG0019	diaminopimelate decarboxylase activity
KAM339_012780	COG1115	amino acid carrier protein
KAM339_012790	COG0095	Lipoate-protein ligase
KAM339_012800	COG2233	PERMEase
KAM339_012840	COG2207	Transcriptional regulator
KAM339_012850	COG0281	malic enzyme
KAM339_012910	COG0733	neurotransmitter:sodium symporter activity
KAM339_012920	COG1752	Esterase of the alpha-beta hydrolase superfamily
KAM339_012930	COG3706	GGDEF domain
KAM339_012950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM339_012960	COG1032	radical SAM domain protein
KAM339_013010	COG0673	inositol 2-dehydrogenase activity
KAM339_013030	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KAM339_013040	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KAM339_013050	COG0739	heme binding
KAM339_013050	COG0741	lytic transglycosylase activity
KAM339_013050	COG1196	nuclear chromosome segregation
KAM339_013100	COG0788	formyltetrahydrofolate deformylase activity
KAM339_013110	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KAM339_013130	COG3118	belongs to the thioredoxin family
KAM339_013150	COG0791	NLP P60 protein
KAM339_013160	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
KAM339_013190	COG1388	LysM domain
KAM339_013190	COG1376	ErfK ybiS ycfS ynhG family protein
KAM339_013200	COG2205	protein histidine kinase activity
KAM339_013200	COG0784	Response regulator, receiver
KAM339_013230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM339_013230	COG2205	protein histidine kinase activity
KAM339_013240	COG3384	dioxygenase
KAM339_013260	COG1283	sodium-dependent phosphate transmembrane transporter activity
KAM339_013280	COG0531	amino acid
KAM339_013290	COG0531	amino acid
KAM339_013320	COG1012	belongs to the aldehyde dehydrogenase family
KAM339_013330	COG1396	sequence-specific DNA binding
KAM339_013330	COG1917	Cupin 2, conserved barrel domain protein
KAM339_013340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAM339_013410	COG4651	solute:proton antiporter activity
KAM339_013410	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KAM339_013440	COG2974	May be involved in recombination
KAM339_013450	COG1247	-acetyltransferase
KAM339_013470	COG0420	3'-5' exonuclease activity
KAM339_013490	COG3038	cytochrome b561
KAM339_013500	COG2190	(PTS) system
KAM339_013520	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM339_013530	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KAM339_013540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KAM339_013570	COG1720	tRNA m6t6A37 methyltransferase activity
KAM339_013610	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KAM339_013620	COG4988	ABC transporter
KAM339_013630	COG0745	RESPONSE REGULATOR receiver
KAM339_013650	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KAM339_013680	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
KAM339_013690	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
KAM339_013710	COG0083	homoserine kinase activity
KAM339_013720	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KAM339_013780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KAM339_013800	COG3220	belongs to the UPF0276 family
KAM339_013860	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KAM339_013880	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KAM339_013890	COG1289	transmembrane transporter activity
KAM339_013900	COG1763	Mo-molybdopterin cofactor biosynthetic process
KAM339_013910	COG0746	molybdenum cofactor guanylyltransferase activity
KAM339_013920	COG0281	malic enzyme
KAM339_013980	COG1196	nuclear chromosome segregation
KAM339_013980	COG3264	Mechanosensitive ion channel
KAM339_014000	COG2850	peptidyl-arginine hydroxylation
KAM339_014010	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KAM339_014020	COG2915	High frequency lysogenization protein hflD homolog
KAM339_014030	COG0482	sulfurtransferase activity
KAM339_014050	COG1187	pseudouridine synthase activity
KAM339_014060	COG0456	acetyltransferase
KAM339_014070	COG0789	Transcriptional regulator
KAM339_014160	COG0538	isocitrate dehydrogenase activity
KAM339_014180	COG3048	D-serine ammonia-lyase activity
KAM339_014190	COG0583	DNA-binding transcription factor activity
KAM339_014200	COG2916	Histone family protein nucleoid-structuring protein H-NS
KAM339_014210	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAM339_014220	COG2375	cellular response to nickel ion
KAM339_014230	COG1538	Outer membrane efflux protein
KAM339_014240	COG1136	(ABC) transporter
KAM339_014240	COG0577	efflux transmembrane transporter activity
KAM339_014250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM339_014270	COG0497	DNA recombination
KAM339_014280	COG3706	GGDEF domain
KAM339_014290	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KAM339_014310	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KAM339_014320	COG0443	Heat shock 70 kDa protein
KAM339_014330	COG0484	heat shock protein binding
KAM339_014400	COG1285	pathogenesis
KAM339_014420	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAM339_014440	COG0640	Transcriptional regulator
KAM339_014500	COG0095	Lipoate-protein ligase
KAM339_014530	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM339_014540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM339_014570	COG0708	Exodeoxyribonuclease III
KAM339_014590	COG0745	RESPONSE REGULATOR receiver
KAM339_014620	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
KAM339_014650	COG1846	Transcriptional regulator
KAM339_014680	COG0675	Transposase, IS605 OrfB family
KAM339_014710	COG0583	DNA-binding transcription factor activity
KAM339_014720	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KAM339_014730	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KAM339_014740	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KAM339_014750	COG1845	cytochrome c oxidase, subunit III
KAM339_014760	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KAM339_014770	COG0109	protoheme IX farnesyltransferase activity
KAM339_014780	COG2814	Major facilitator Superfamily
KAM339_014790	COG5507	3-demethylubiquinone-9 3-methyltransferase
KAM339_014810	COG2175	clavaminate synthase activity
KAM339_014820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KAM339_014830	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KAM339_014840	COG4521	taurine ABC transporter
KAM339_014900	COG3550	peptidyl-serine autophosphorylation
KAM339_014910	COG1396	sequence-specific DNA binding
KAM339_014920	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KAM339_014930	COG5433	transposase activity
KAM339_014940	COG3039	Transposase
KAM339_014950	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KAM339_014960	COG0159	tryptophan synthase activity
KAM339_014970	COG0133	tryptophan synthase activity
KAM339_014980	COG0134	indole-3-glycerol-phosphate synthase activity
KAM339_014980	COG0135	phosphoribosylanthranilate isomerase activity
KAM339_014990	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KAM339_015000	COG0512	Glutamine amidotransferase of anthranilate synthase
KAM339_015000	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KAM339_015010	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KAM339_015020	COG0613	PHP domain protein
KAM339_015030	COG0009	L-threonylcarbamoyladenylate synthase
KAM339_015050	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KAM339_015070	COG1946	Acyl-CoA thioesterase
KAM339_015100	COG1309	transcriptional regulator
KAM339_015110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM339_015120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM339_015150	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KAM339_015170	COG1960	acyl-CoA dehydrogenase activity
KAM339_015180	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM339_015200	COG0469	pyruvate kinase activity
KAM339_015210	COG1737	Transcriptional regulator
KAM339_015220	COG5433	transposase activity
KAM339_015230	COG1737	Transcriptional regulator
KAM339_015240	COG3385	transposase activity
KAM339_015260	COG3385	transposase activity
KAM339_015310	COG1091	dTDP-4-dehydrorhamnose reductase activity
KAM339_015340	COG2244	polysaccharide biosynthetic process
KAM339_015350	COG0562	UDP-galactopyranose mutase
KAM339_015410	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KAM339_015450	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
KAM339_015500	COG3132	Protein of unknown function, DUF480
KAM339_015510	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KAM339_015590	COG1278	Cold shock
KAM339_015640	COG0675	Transposase, IS605 OrfB family
KAM339_015660	COG4166	transmembrane transport
KAM339_015670	COG0697	spore germination
KAM339_015690	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KAM339_015720	COG4166	transmembrane transport
KAM339_015740	COG0675	Transposase, IS605 OrfB family
KAM339_015750	COG0622	Phosphoesterase
KAM339_015780	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
KAM339_015790	COG0835	chemotaxis
KAM339_015790	COG0784	Response regulator, receiver
KAM339_015800	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KAM339_015810	COG1815	bacterial-type flagellum-dependent cell motility
KAM339_015840	COG1749	Flagellar hook protein flgE
KAM339_015870	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KAM339_015880	COG1706	bacterial-type flagellum-dependent cell motility
KAM339_015890	COG1705	Flagellar rod assembly protein muramidase FlgJ
KAM339_015890	COG3951	Flagellar rod assembly protein muramidase FlgJ
KAM339_015920	COG2239	Acts as a magnesium transporter
KAM339_015940	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KAM339_015950	COG2716	regulation of RNA biosynthetic process
KAM339_016000	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KAM339_016010	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KAM339_016020	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KAM339_016030	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KAM339_016070	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KAM339_016080	COG0590	tRNA wobble adenosine to inosine editing
KAM339_016090	COG0573	inorganic phosphate transmembrane transporter activity
KAM339_016100	COG0581	inorganic phosphate transmembrane transporter activity
KAM339_016110	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KAM339_016120	COG0704	Plays a role in the regulation of phosphate uptake
KAM339_016130	COG1253	flavin adenine dinucleotide binding
KAM339_016160	COG0531	amino acid
KAM339_016180	COG1126	abc transporter atp-binding protein
KAM339_016190	COG0765	amino acid transport
KAM339_016200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM339_016210	COG3706	GGDEF domain
KAM339_016220	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KAM339_016260	COG1785	Belongs to the alkaline phosphatase family
KAM339_016270	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KAM339_016280	COG0477	Major facilitator Superfamily
KAM339_016290	COG0123	including yeast histone deacetylase and acetoin utilization protein
KAM339_016310	COG1199	ATP-dependent helicase activity
KAM339_016350	COG1448	Aminotransferase
KAM339_016360	COG0433	COG0433 Predicted ATPase
KAM339_016390	COG0658	competence protein
KAM339_016390	COG2333	competence protein COMEC
KAM339_016400	COG1132	(ABC) transporter
KAM339_016410	COG1663	tetraacyldisaccharide 4'-kinase activity
KAM339_016420	COG2835	tetraacyldisaccharide 4'-kinase activity
KAM339_016430	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KAM339_016440	COG2197	response regulator
KAM339_016450	COG0322	excinuclease ABC activity
KAM339_016480	COG0604	alcohol dehydrogenase
KAM339_016490	COG1309	transcriptional regulator
KAM339_016500	COG2261	transglycosylase associated protein
KAM339_016510	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAM339_016530	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KAM339_016590	COG2801	Transposase and inactivated derivatives
KAM339_016590	COG3415	Transposase
KAM339_016610	COG1074	ATP-dependent DNA helicase activity
KAM339_016630	COG5433	transposase activity
KAM339_016650	COG2199	diguanylate cyclase activity
KAM339_016650	COG2203	Gaf domain
KAM339_016720	COG2119	membrane
KAM339_016730	COG0023	Translation Initiation Factor
KAM339_016750	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KAM339_016800	COG4139	cobalamin transport
KAM339_016810	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
KAM339_016820	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAM339_016830	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KAM339_016840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KAM339_016850	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KAM339_016860	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KAM339_016880	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KAM339_016890	COG0505	Belongs to the CarA family
KAM339_016900	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KAM339_016910	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KAM339_016920	COG3706	GGDEF domain
KAM339_016980	COG0513	Belongs to the DEAD box helicase family
KAM339_017000	COG4104	PAAR repeat-containing protein
KAM339_017050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM339_017060	COG0765	amino acid transport
KAM339_017070	COG1126	abc transporter atp-binding protein
KAM339_017080	COG0493	'glutamate synthase
KAM339_017090	COG0070	glutamate synthase
KAM339_017090	COG0067	glutamate synthase
KAM339_017090	COG0069	glutamate synthase activity
KAM339_017100	COG1242	4 iron, 4 sulfur cluster binding
KAM339_017210	COG1113	amino acid transport
KAM339_017230	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KAM339_017240	COG0574	Belongs to the PEP-utilizing enzyme family
KAM339_017240	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KAM339_017250	COG1119	ATPase activity
KAM339_017290	COG1464	Belongs to the NlpA lipoprotein family
KAM339_017300	COG0671	phosphoesterase, PA-phosphatase related
KAM339_017310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KAM339_017320	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KAM339_017340	COG0101	tRNA pseudouridine synthase activity
KAM339_017350	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KAM339_017360	COG0285	dihydrofolate synthase activity
KAM339_017370	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
KAM339_017380	COG2920	part of a sulfur-relay system
KAM339_017390	COG1289	transmembrane transporter activity
KAM339_017400	COG0670	Belongs to the BI1 family
KAM339_017480	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KAM339_017490	COG0840	transmembrane signaling receptor activity
KAM339_017500	COG5001	Diguanylate cyclase
KAM339_017510	COG0564	pseudouridine synthase activity
KAM339_017540	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KAM339_017560	COG0625	glutathione transferase activity
KAM339_017590	COG0367	asparagine synthase
KAM339_017610	COG0647	UMP catabolic process
KAM339_017620	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KAM339_017640	COG1902	pentaerythritol trinitrate reductase activity
KAM339_017650	COG1253	flavin adenine dinucleotide binding
KAM339_017670	COG0247	lactate metabolic process
KAM339_017670	COG0277	FAD linked oxidase domain protein
KAM339_017690	COG2050	protein possibly involved in aromatic compounds catabolism
KAM339_017720	COG5001	Diguanylate cyclase
KAM339_017730	COG0583	DNA-binding transcription factor activity
KAM339_017740	COG2814	Major facilitator Superfamily
KAM339_017750	COG2056	Na+-H+ antiporter family
KAM339_017760	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KAM339_017800	COG0483	inositol monophosphate 1-phosphatase activity
KAM339_017820	COG0625	glutathione transferase activity
KAM339_017830	COG0625	glutathione transferase activity
KAM339_017850	COG0601	transmembrane transport
KAM339_017860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAM339_017870	COG0444	Belongs to the ABC transporter superfamily
KAM339_017880	COG2814	Major facilitator Superfamily
KAM339_017910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KAM339_017920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KAM339_017930	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KAM339_017940	COG0509	glycine decarboxylation via glycine cleavage system
KAM339_017950	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KAM339_017950	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KAM339_017990	COG0477	Major facilitator Superfamily
KAM339_018000	COG3634	alkyl hydroperoxide reductase activity
KAM339_018010	COG0450	alkyl hydroperoxide reductase
KAM339_018020	COG0517	IMP dehydrogenase activity
KAM339_018030	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KAM339_018040	COG0343	queuine tRNA-ribosyltransferase activity
KAM339_018050	COG1862	Preprotein translocase
KAM339_018060	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAM339_018070	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAM339_018080	COG2897	thiosulfate sulfurtransferase activity
KAM339_018100	COG0826	peptidase U32
KAM339_018110	COG0826	peptidase U32
KAM339_018130	COG3154	lipid carrier protein
KAM339_018160	COG1104	cysteine desulfurase activity
KAM339_018170	COG0822	iron-sulfur transferase activity
KAM339_018190	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KAM339_018200	COG0443	Heat shock 70 kDa protein
KAM339_018210	COG0633	Ferredoxin
KAM339_018230	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KAM339_018240	COG0105	UTP biosynthetic process
KAM339_018250	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KAM339_018270	COG1426	Protein conserved in bacteria
KAM339_018290	COG0124	histidyl-tRNA synthetase
KAM339_018300	COG2976	Protein conserved in bacteria
KAM339_018310	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAM339_018320	COG1160	GTP binding
KAM339_018330	COG1645	bacterial-type flagellum-dependent swarming motility
KAM339_018340	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KAM339_018350	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KAM339_018350	COG0047	phosphoribosylformylglycinamidine synthase activity
KAM339_018360	COG1007	ATP synthesis coupled electron transport
KAM339_018370	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM339_018390	COG0713	ATP synthesis coupled electron transport
KAM339_018400	COG0839	Belongs to the complex I subunit 6 family
KAM339_018410	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM339_018420	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KAM339_018430	COG1034	ATP synthesis coupled electron transport
KAM339_018460	COG0649	NAD binding
KAM339_018460	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM339_018470	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM339_018480	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM339_018490	COG1360	Flagellar Motor Protein
KAM339_018500	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KAM339_018520	COG4584	PFAM Integrase catalytic
KAM339_018530	COG1484	DNA-dependent DNA replication
KAM339_018580	COG4974	Belongs to the 'phage' integrase family
KAM339_018610	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KAM339_018650	COG0724	RNA recognition motif
KAM339_018660	COG4989	oxidoreductase activity
KAM339_018710	COG0745	RESPONSE REGULATOR receiver
KAM339_018720	COG0583	DNA-binding transcription factor activity
KAM339_018740	COG5001	Diguanylate cyclase
KAM339_018740	COG3300	MHYT domain
KAM339_018750	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KAM339_018810	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KAM339_018820	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KAM339_018830	COG0539	negative regulation of cytoplasmic translation
KAM339_018840	COG0776	regulation of translation
KAM339_018860	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KAM339_018900	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KAM339_018910	COG0602	queuosine metabolic process
KAM339_018920	COG3530	Putative quorum-sensing-regulated virulence factor
KAM339_018930	COG2096	Adenosyltransferase
KAM339_018940	COG2916	Histone family protein nucleoid-structuring protein H-NS
KAM339_018950	COG1757	Na H antiporter
KAM339_018960	COG1435	thymidine kinase activity
KAM339_019000	COG1737	Transcriptional regulator
KAM339_019010	COG1263	PTS System
KAM339_019010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM339_019010	COG2190	(PTS) system
KAM339_019020	COG2723	6-phospho-beta-galactosidase activity
KAM339_019060	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
KAM339_019070	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KAM339_019080	COG0626	cystathionine gamma-synthase activity
KAM339_019100	COG2910	NAD(P)H-binding
KAM339_019110	COG0583	DNA-binding transcription factor activity
KAM339_019120	COG4977	sequence-specific DNA binding
KAM339_019120	COG1917	Cupin 2, conserved barrel domain protein
KAM339_019130	COG2200	EAL domain
KAM339_019140	COG3706	GGDEF domain
KAM339_019150	COG4774	siderophore transport
KAM339_019170	COG0583	DNA-binding transcription factor activity
KAM339_019180	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KAM339_019200	COG0517	IMP dehydrogenase activity
KAM339_019200	COG0617	tRNA 3'-terminal CCA addition
KAM339_019200	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KAM339_019210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAM339_019220	COG3046	protein related to deoxyribodipyrimidine photolyase
KAM339_019240	COG3088	subunit of a heme lyase
KAM339_019240	COG4235	cytochrome complex assembly
KAM339_019250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KAM339_019260	COG1138	Cytochrome C-type biogenesis protein
KAM339_019270	COG3301	Polysulphide reductase, NrfD
KAM339_019280	COG0437	4 iron, 4 sulfur cluster binding
KAM339_019290	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
KAM339_019320	COG0247	lactate metabolic process
KAM339_019330	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KAM339_019340	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KAM339_019350	COG3012	SEC-C Motif Domain Protein
KAM339_019360	COG0840	transmembrane signaling receptor activity
KAM339_019370	COG1846	Transcriptional regulator
KAM339_019370	COG1940	carbohydrate kinase activity
KAM339_019380	COG3290	protein histidine kinase activity
KAM339_019390	COG4565	transcriptional regulatory protein
KAM339_019430	COG0739	heme binding
KAM339_019430	COG1196	nuclear chromosome segregation
KAM339_019430	COG0741	lytic transglycosylase activity
KAM339_019440	COG2985	domain, Protein
KAM339_019440	COG0569	domain protein
KAM339_019450	COG0556	nucleotide-excision repair
KAM339_019470	COG0586	Pfam SNARE associated Golgi protein
KAM339_019480	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KAM339_019490	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KAM339_019500	COG2186	Transcriptional regulator
KAM339_019510	COG2719	SpoVR family
KAM339_019520	COG2718	Belongs to the UPF0229 family
KAM339_019530	COG2766	serine protein kinase
KAM339_019540	COG0514	ATP-dependent DNA helicase (RecQ)
KAM339_019550	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KAM339_019560	COG0814	amino acid
KAM339_019620	COG0058	SHG alpha-glucan phosphorylase activity
KAM339_019640	COG0471	metal ion transport
KAM339_019650	COG3118	belongs to the thioredoxin family
KAM339_019670	COG1132	(ABC) transporter
KAM339_019680	COG1132	(ABC) transporter
KAM339_019710	COG2501	S4 domain
KAM339_019730	COG3243	poly(R)-hydroxyalkanoic acid synthase
KAM339_019770	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KAM339_019780	COG2329	Antibiotic biosynthesis monooxygenase
KAM339_019830	COG1742	UPF0060 membrane protein
KAM339_019860	COG0513	Belongs to the DEAD box helicase family
KAM339_019870	COG0386	Belongs to the glutathione peroxidase family
KAM339_019890	COG1181	Belongs to the D-alanine--D-alanine ligase family
KAM339_019900	COG3148	PFAM DTW domain containing protein
KAM339_019910	COG0730	response to heat
KAM339_019920	COG0583	DNA-binding transcription factor activity
KAM339_019950	COG3593	DNA synthesis involved in DNA repair
KAM339_019970	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KAM339_019980	COG1011	Hydrolase
KAM339_019990	COG1473	amidohydrolase
KAM339_020000	COG0205	6-phosphofructokinase activity
KAM339_020020	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KAM339_020030	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KAM339_020050	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
KAM339_020060	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KAM339_020140	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KAM339_020150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KAM339_020210	COG1280	lysine exporter protein (LysE YggA)
KAM339_020230	COG2824	Alkylphosphonate utilization operon protein PhnA
KAM339_020300	COG2840	Smr protein MutS2
KAM339_020310	COG2890	protein-(glutamine-N5) methyltransferase activity
KAM339_020320	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KAM339_020340	COG0513	Belongs to the DEAD box helicase family
KAM339_020350	COG5654	RES domain protein
KAM339_020370	COG0814	amino acid
KAM339_020380	COG1609	Transcriptional regulator
KAM339_020390	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM339_020390	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM339_020400	COG1105	Belongs to the carbohydrate kinase PfkB family
KAM339_020410	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KAM339_020410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KAM339_020410	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KAM339_020420	COG3313	Fe-S protein
KAM339_020430	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
KAM339_020440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KAM339_020450	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KAM339_020460	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KAM339_020480	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KAM339_020530	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KAM339_020540	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KAM339_020550	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KAM339_020560	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KAM339_020820	COG4695	Portal protein
KAM339_021080	COG4974	Belongs to the 'phage' integrase family
KAM339_021090	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KAM339_021100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM339_021100	COG0072	phenylalanine-tRNA ligase activity
KAM339_021110	COG0776	regulation of translation
KAM339_021170	COG3300	MHYT domain
KAM339_021170	COG5001	Diguanylate cyclase
KAM339_021180	COG1609	Transcriptional regulator
KAM339_021190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM339_021200	COG1879	ABC-type sugar transport system periplasmic component
KAM339_021210	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAM339_021220	COG1129	ABC transporter
KAM339_021230	COG1869	D-ribose catabolic process
KAM339_021240	COG0625	glutathione transferase activity
KAM339_021270	COG0037	tRNA processing
KAM339_021280	COG0589	response to stress
KAM339_021290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KAM339_021320	COG2217	Heavy metal translocating P-type atpase
KAM339_021340	COG2010	Cytochrome c
KAM339_021370	COG3278	Belongs to the heme-copper respiratory oxidase family
KAM339_021390	COG1956	GAF domain-containing protein
KAM339_021400	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
KAM339_021420	COG0308	aminopeptidase N
KAM339_021440	COG2902	Dehydrogenase
KAM339_021450	COG0167	dihydroorotate dehydrogenase activity
KAM339_021480	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KAM339_021480	COG0116	Belongs to the methyltransferase superfamily
KAM339_021500	COG0488	(ABC) transporter
KAM339_021530	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KAM339_021540	COG1067	ATP-dependent peptidase activity
KAM339_021560	COG3141	response to X-ray
KAM339_021580	COG2995	paraquat-inducible protein a
KAM339_021590	COG3008	intermembrane lipid transfer
KAM339_021600	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KAM339_021600	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
KAM339_021620	COG2801	Transposase and inactivated derivatives
KAM339_021690	COG0084	hydrolase, TatD family'
KAM339_021700	COG0470	DNA polymerase III
KAM339_021710	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KAM339_021720	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KAM339_021730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KAM339_021740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KAM339_021750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KAM339_021760	COG1028	Short-chain dehydrogenase reductase Sdr
KAM339_021780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KAM339_021790	COG0416	fatty acid biosynthetic process
KAM339_021800	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KAM339_021810	COG1399	metal-binding, possibly nucleic acid-binding protein
KAM339_021840	COG0564	pseudouridine synthase activity
KAM339_021850	COG1530	ribonuclease E activity
KAM339_021860	COG0306	phosphate transporter
KAM339_021870	COG0717	Belongs to the dCTP deaminase family
KAM339_021880	COG0572	uridine kinase
KAM339_021890	COG0489	protein tyrosine kinase activity
KAM339_021900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM339_021900	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM339_021910	COG0625	glutathione transferase activity
KAM339_021920	COG1254	Belongs to the acylphosphatase family
KAM339_021930	COG0840	transmembrane signaling receptor activity
KAM339_021940	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KAM339_021980	COG0709	Synthesizes selenophosphate from selenide and ATP
KAM339_021990	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
KAM339_022000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KAM339_022010	COG3437	response regulator, receiver
KAM339_022030	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KAM339_022050	COG1643	Atp-dependent helicase
KAM339_022060	COG0617	tRNA 3'-terminal CCA addition
KAM339_022060	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KAM339_022060	COG0517	IMP dehydrogenase activity
KAM339_022070	COG2197	response regulator
KAM339_022080	COG3314	Sporulation integral membrane protein YlbJ
KAM339_022100	COG0583	DNA-binding transcription factor activity
KAM339_022110	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KAM339_022130	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KAM339_022140	COG2832	Protein of unknown function (DUF454)
KAM339_022150	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KAM339_022180	COG0697	spore germination
KAM339_022200	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KAM339_022210	COG0318	PFAM AMP-dependent synthetase and ligase
KAM339_022220	COG0596	Alpha beta hydrolase
KAM339_022240	COG1214	PFAM Peptidase M22, glycoprotease
KAM339_022250	COG1199	ATP-dependent helicase activity
KAM339_022270	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KAM339_022280	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KAM339_022290	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KAM339_022300	COG0131	Imidazoleglycerol-phosphate dehydratase
KAM339_022300	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KAM339_022310	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KAM339_022320	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KAM339_022330	COG3437	response regulator, receiver
KAM339_022340	COG2199	diguanylate cyclase activity
KAM339_022350	COG0784	Response regulator, receiver
KAM339_022350	COG2198	Histidine kinase
KAM339_022350	COG2205	protein histidine kinase activity
KAM339_022360	COG0107	imidazoleglycerol-phosphate synthase activity
KAM339_022370	COG0140	phosphoribosyl-ATP diphosphatase activity
KAM339_022370	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KAM339_022390	COG2378	regulation of single-species biofilm formation
KAM339_022400	COG0318	PFAM AMP-dependent synthetase and ligase
KAM339_022410	COG3134	Outer membrane lipoprotein
KAM339_022440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAM339_022500	COG4681	YaeQ
KAM339_022520	COG1024	Enoyl-CoA hydratase
KAM339_022520	COG1250	3-hydroxyacyl-CoA dehydrogenase
KAM339_022530	COG0183	Belongs to the thiolase family
KAM339_022540	COG0714	Associated with various cellular activities
KAM339_022600	COG1595	DNA-templated transcription, initiation
KAM339_022620	COG2067	long-chain fatty acid transport protein
KAM339_022630	COG2067	long-chain fatty acid transport protein
KAM339_022640	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KAM339_022670	COG1301	dicarboxylic acid transport
KAM339_022680	COG3123	guanosine phosphorylase activity
KAM339_022690	COG1760	l-serine dehydratase
KAM339_022700	COG1760	l-serine dehydratase
KAM339_022710	COG2951	lytic endotransglycosylase activity
KAM339_022720	COG3100	YcgL domain-containing protein
KAM339_022730	COG0850	regulation of cytokinetic process
KAM339_022740	COG2894	cell division
KAM339_022750	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KAM339_022760	COG3099	Belongs to the UPF0263 family
KAM339_022770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KAM339_022800	COG2996	Protein conserved in bacteria
KAM339_022850	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KAM339_022860	COG0697	spore germination
KAM339_022870	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KAM339_022880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAM339_022910	COG1484	DNA-dependent DNA replication
KAM339_022920	COG4584	PFAM Integrase catalytic
KAM339_023060	COG4584	PFAM Integrase catalytic
KAM339_023070	COG1484	DNA-dependent DNA replication
KAM339_023150	COG0307	riboflavin synthase, alpha
KAM339_023170	COG0534	Mate efflux family protein
KAM339_023180	COG0417	DNA replication proofreading
KAM339_023210	COG1560	Kdo2-lipid A biosynthetic process
KAM339_023220	COG1560	Kdo2-lipid A biosynthetic process
KAM339_023240	COG0583	DNA-binding transcription factor activity
KAM339_023250	COG0673	inositol 2-dehydrogenase activity
KAM339_023260	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KAM339_023300	COG0583	DNA-binding transcription factor activity
KAM339_023320	COG2723	6-phospho-beta-galactosidase activity
KAM339_023330	COG0583	DNA-binding transcription factor activity
KAM339_023350	COG0243	molybdopterin cofactor binding
KAM339_023360	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KAM339_023390	COG0583	DNA-binding transcription factor activity
KAM339_023400	COG1879	ABC-type sugar transport system periplasmic component
KAM339_023410	COG1129	ABC transporter
KAM339_023420	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAM339_023430	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAM339_023640	COG0653	protein targeting
KAM339_023660	COG0730	response to heat
KAM339_023680	COG1028	Short-chain dehydrogenase reductase Sdr
KAM339_023700	COG1024	Enoyl-CoA hydratase
KAM339_023710	COG1024	Enoyl-CoA hydratase
KAM339_023720	COG1960	acyl-CoA dehydrogenase activity
KAM339_023740	COG1960	acyl-CoA dehydrogenase activity
KAM339_023750	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KAM339_023760	COG1024	Enoyl-CoA hydratase
KAM339_023810	COG1584	GPR1 FUN34 yaaH family protein
KAM339_023820	COG3228	Belongs to the MtfA family
KAM339_023840	COG1115	amino acid carrier protein
KAM339_023850	COG1024	Enoyl-CoA hydratase
KAM339_023880	COG3162	membrane
KAM339_023890	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KAM339_023900	COG0488	(ABC) transporter
KAM339_023920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KAM339_023930	COG0776	regulation of translation
KAM339_023940	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KAM339_023950	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KAM339_023960	COG0740	serine-type endopeptidase activity
KAM339_023970	COG0544	peptidyl-prolyl cis-trans isomerase activity
KAM339_024000	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KAM339_024010	COG4591	ABC-type transport system involved in lipoprotein release permease component
KAM339_024020	COG1136	(ABC) transporter
KAM339_024030	COG4591	ABC-type transport system involved in lipoprotein release permease component
KAM339_024060	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KAM339_024070	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
KAM339_024090	COG0697	spore germination
KAM339_024110	COG2062	phosphohistidine phosphatase, SixA
KAM339_024130	COG0500	methyltransferase
KAM339_024150	COG1846	Transcriptional regulator
KAM339_024200	COG3039	Transposase
KAM339_024230	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KAM339_024230	COG0519	Catalyzes the synthesis of GMP from XMP
KAM339_024240	COG0516	GMP reductase activity
KAM339_024240	COG0517	IMP dehydrogenase activity
KAM339_024260	COG0366	Alpha amylase catalytic
KAM339_024260	COG1874	Beta-galactosidase
KAM339_024310	COG1570	exodeoxyribonuclease VII activity
KAM339_024330	COG2885	chlorophyll binding
KAM339_024370	COG2154	pterin-4-alpha-carbinolamine dehydratase
KAM339_024390	COG3768	UPF0283 membrane protein
KAM339_024400	COG3106	COG3106 Predicted ATPase
KAM339_024430	COG1842	Phage shock protein A
KAM339_024440	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KAM339_024480	COG4171	peptide transport system, permease
KAM339_024500	COG4172	Belongs to the ABC transporter superfamily
KAM339_024520	COG1609	Transcriptional regulator
KAM339_024530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM339_024530	COG1263	PTS System
KAM339_024540	COG2723	6-phospho-beta-galactosidase activity
KAM339_024550	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KAM339_024560	COG1286	toxin biosynthetic process
KAM339_024570	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KAM339_024580	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KAM339_024590	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KAM339_024600	COG0531	amino acid
KAM339_024600	COG1674	ftsk spoiiie
KAM339_024620	COG0686	Belongs to the AlaDH PNT family
KAM339_024640	COG0492	ferredoxin-NADP+ reductase activity
KAM339_024650	COG3706	GGDEF domain
KAM339_024660	COG3134	Outer membrane lipoprotein
KAM339_024670	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KAM339_024680	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KAM339_024690	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KAM339_024700	COG0542	response to heat
KAM339_024710	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KAM339_024720	COG1278	Cold shock
KAM339_024730	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KAM339_024760	COG1944	ATP diphosphatase activity
KAM339_024770	COG2116	formate transmembrane transporter activity
KAM339_024780	COG1882	Formate acetyltransferase
KAM339_024790	COG2983	Belongs to the UPF0260 family
KAM339_024830	COG4584	PFAM Integrase catalytic
KAM339_024840	COG1484	DNA-dependent DNA replication
KAM339_024860	COG2983	Belongs to the UPF0260 family
KAM339_024890	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KAM339_024900	COG0045	succinate-CoA ligase (ADP-forming) activity
KAM339_024910	COG0508	dehydrogenase complex catalyzes the overall conversion of
KAM339_024920	COG0567	Dehydrogenase, E1 component
KAM339_024950	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KAM339_024960	COG2009	succinate dehydrogenase
KAM339_025000	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KAM339_025010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAM339_025010	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KAM339_025030	COG3069	C4-dicarboxylate transmembrane transporter activity
KAM339_025060	COG1451	nucleotide metabolic process
KAM339_025090	COG0254	rRNA binding
KAM339_025110	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAM339_025120	COG1129	ABC transporter
KAM339_025130	COG1879	ABC-type sugar transport system periplasmic component
KAM339_025140	COG1069	ribulokinase activity
KAM339_025160	COG2160	L-arabinose isomerase activity
KAM339_025190	COG0556	nucleotide-excision repair
KAM339_025200	COG0514	ATP-dependent DNA helicase (RecQ)
KAM339_025210	COG0583	DNA-binding transcription factor activity
KAM339_025220	COG0436	Aminotransferase
KAM339_025230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KAM339_025260	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KAM339_025260	COG0392	lysyltransferase activity
KAM339_025270	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KAM339_025290	COG0469	pyruvate kinase activity
KAM339_025310	COG1263	PTS System
KAM339_025310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM339_025320	COG1874	Beta-galactosidase
KAM339_025330	COG3867	Arabinogalactan endo-beta-1,4-galactanase
KAM339_025340	COG3833	ABC-type maltose transport systems, permease component
KAM339_025350	COG1175	transmembrane transport
KAM339_025360	COG2182	Extracellular solute-binding protein
KAM339_025410	COG4580	involved in the transport of maltose and maltodextrins
KAM339_025420	COG1609	Transcriptional regulator
KAM339_025430	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KAM339_025450	COG1484	DNA-dependent DNA replication
KAM339_025460	COG4584	PFAM Integrase catalytic
KAM339_025470	COG1085	galactose-1-phosphate uridylyltransferase
KAM339_025520	COG0300	oxidoreductase activity
KAM339_025530	COG1902	pentaerythritol trinitrate reductase activity
KAM339_025580	COG3039	Transposase
KAM339_026040	COG2314	TM2 domain
KAM339_026180	COG0582	viral genome integration into host DNA
KAM339_026190	COG2925	Exonuclease
KAM339_026210	COG3345	alpha-galactosidase
KAM339_026220	COG1380	Effector of murein hydrolase LrgA
KAM339_026230	COG1346	cytolysis
KAM339_026240	COG0295	cytidine deaminase activity
KAM339_026250	COG1022	Amp-dependent synthetase and ligase
KAM339_026280	COG0861	Integral membrane protein TerC family
KAM339_026290	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAM339_026300	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KAM339_026310	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KAM339_026390	COG4771	TonB-dependent receptor
KAM339_026400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAM339_026410	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAM339_026420	COG1120	ATPase activity
KAM339_026450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KAM339_026470	COG1028	Short-chain dehydrogenase reductase Sdr
KAM339_026480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KAM339_026490	COG1535	isochorismatase
KAM339_026490	COG3433	isochorismatase activity
KAM339_026500	COG1021	2,3-dihydroxybenzoate-AMP ligase
KAM339_026550	COG5001	Diguanylate cyclase
KAM339_026550	COG3300	MHYT domain
KAM339_026580	COG0840	transmembrane signaling receptor activity
KAM339_026590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM339_026600	COG3788	relative of glutathione S-transferase, MAPEG superfamily
KAM339_026610	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KAM339_026620	COG0563	adenylate kinase activity
KAM339_026630	COG0326	Molecular chaperone. Has ATPase activity
KAM339_026650	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KAM339_026660	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KAM339_026670	COG0298	carbon dioxide binding
KAM339_026690	COG0309	Hydrogenase expression formation protein (HypE)
KAM339_026700	COG0375	protein maturation
KAM339_026720	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KAM339_026730	COG3842	ATPase activity
KAM339_026750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAM339_026760	COG0601	transmembrane transport
KAM339_026780	COG1773	rubredoxin
KAM339_026790	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KAM339_026800	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KAM339_026810	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
KAM339_026820	COG5557	Pfam Polysulphide reductase, NrfD
KAM339_026830	COG0437	4 iron, 4 sulfur cluster binding
KAM339_026840	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
KAM339_026850	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KAM339_026910	COG4974	Belongs to the 'phage' integrase family
KAM339_026930	COG0659	secondary active sulfate transmembrane transporter activity
KAM339_026950	COG2308	Evidence 4 Homologs of previously reported genes of
KAM339_027020	COG0672	)-iron permease
KAM339_027070	COG2814	Major facilitator Superfamily
KAM339_027110	COG1136	(ABC) transporter
KAM339_027120	COG0577	efflux transmembrane transporter activity
KAM339_027180	COG1139	Iron-sulfur cluster binding protein
KAM339_027190	COG0247	lactate metabolic process
KAM339_027200	COG1620	l-lactate permease
KAM339_027210	COG0583	DNA-binding transcription factor activity
KAM339_027260	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KAM339_027270	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KAM339_027270	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KAM339_027280	COG0527	aspartate kinase activity
KAM339_027300	COG1368	sulfuric ester hydrolase activity
KAM339_027310	COG0393	Putative heavy-metal-binding
KAM339_027340	COG1252	NADH dehydrogenase
KAM339_027350	COG3150	esterase
KAM339_027360	COG1164	Oligoendopeptidase f
KAM339_027370	COG1164	Oligoendopeptidase f
KAM339_027380	COG2354	Protein conserved in bacteria
KAM339_027410	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAM339_027420	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAM339_027490	COG0537	adenosine 5'-monophosphoramidase activity
KAM339_027520	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KAM339_027550	COG1301	dicarboxylic acid transport
KAM339_027570	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KAM339_027580	COG0861	Integral membrane protein TerC family
KAM339_027600	COG0444	Belongs to the ABC transporter superfamily
KAM339_027610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAM339_027620	COG0601	transmembrane transport
KAM339_027640	COG2095	MarC family integral membrane protein
KAM339_027650	COG1012	belongs to the aldehyde dehydrogenase family
KAM339_027650	COG1454	alcohol dehydrogenase
KAM339_027670	COG3275	phosphorelay sensor kinase activity
KAM339_027680	COG3279	Response regulator of the LytR AlgR family
KAM339_027690	COG1966	Carbon starvation protein
KAM339_027700	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KAM339_027700	COG3264	Mechanosensitive ion channel
KAM339_027720	COG1566	PFAM secretion protein HlyD family protein
KAM339_027730	COG1061	Type III restriction enzyme res subunit
KAM339_027740	COG2027	D-alanyl-D-alanine carboxypeptidase
KAM339_027750	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KAM339_027770	COG0436	Aminotransferase
KAM339_027780	COG1288	antiporter activity
KAM339_027790	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KAM339_027830	COG0697	spore germination
KAM339_027840	COG4657	Part of a membrane complex involved in electron transport
KAM339_027850	COG2878	Part of a membrane complex involved in electron transport
KAM339_027870	COG4658	electron transport chain
KAM339_027890	COG4660	Part of a membrane complex involved in electron transport
KAM339_027900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KAM339_027910	COG0346	lactoylglutathione lyase activity
KAM339_027950	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KAM339_027970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KAM339_027990	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KAM339_028010	COG2089	acid synthase
KAM339_028020	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KAM339_028040	COG2226	methyltransferase
KAM339_028060	COG1083	cytidylyl-transferase
KAM339_028190	COG0301	tRNA thio-modification
KAM339_028190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KAM339_028210	COG4953	penicillin-binding protein 1C
KAM339_028220	COG2373	Large extracellular alpha-helical protein
KAM339_028230	COG0628	permease
KAM339_028280	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAM339_028300	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KAM339_028320	COG4160	amino acid transport
KAM339_028340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM339_028360	COG2431	L-lysine efflux transmembrane transporter activity
KAM339_028370	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KAM339_028380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM339_028430	COG1393	Belongs to the ArsC family
KAM339_028450	COG4783	chaperone-mediated protein folding
KAM339_028460	COG0425	Belongs to the sulfur carrier protein TusA family
KAM339_028490	COG0596	Alpha beta hydrolase
KAM339_028510	COG3842	ATPase activity
KAM339_028520	COG3833	ABC-type maltose transport systems, permease component
KAM339_028530	COG1175	transmembrane transport
KAM339_028550	COG3081	Nucleoid-associated protein
KAM339_028560	COG3082	Protein of unknown function (DUF1414)
KAM339_028570	COG3083	sulfuric ester hydrolase activity
KAM339_028580	COG4771	TonB-dependent receptor
KAM339_028590	COG1770	oligopeptidase
KAM339_028630	COG4574	serine-type endopeptidase inhibitor activity
KAM339_028640	COG3085	chromosome segregation
KAM339_028660	COG0287	Prephenate dehydrogenase
KAM339_028660	COG1605	Chorismate mutase
KAM339_028670	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAM339_028680	COG0584	glycerophosphoryl diester phosphodiesterase
KAM339_028700	COG1349	DNA-binding transcription factor activity
KAM339_028710	COG2271	Major facilitator Superfamily
KAM339_028720	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KAM339_028730	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KAM339_028740	COG0583	DNA-binding transcription factor activity
KAM339_028780	COG0656	L-ascorbic acid biosynthetic process
KAM339_028790	COG2814	Major facilitator Superfamily
KAM339_028800	COG1294	oxidase, subunit
KAM339_028810	COG1271	oxidase subunit
KAM339_028820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KAM339_028840	COG2979	Protein of unknown function (DUF533)
KAM339_028880	COG0583	DNA-binding transcription factor activity
KAM339_028900	COG2807	transmembrane transport
KAM339_028910	COG1187	pseudouridine synthase activity
KAM339_028920	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KAM339_028960	COG1061	Type III restriction enzyme res subunit
KAM339_029010	COG1166	arginine decarboxylase activity
KAM339_029020	COG2195	Cleaves the N-terminal amino acid of tripeptides
KAM339_029050	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KAM339_029080	COG0583	DNA-binding transcription factor activity
KAM339_029100	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KAM339_029110	COG0840	transmembrane signaling receptor activity
KAM339_029120	COG0302	gtp cyclohydrolase
KAM339_029140	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KAM339_029150	COG2267	carboxylic ester hydrolase activity
KAM339_029160	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KAM339_029190	COG0314	molybdopterin synthase activity
KAM339_029200	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KAM339_029210	COG0315	cyclic pyranopterin monophosphate synthase activity
KAM339_029220	COG0521	Mo-molybdopterin cofactor biosynthetic process
KAM339_029230	COG3005	denitrification pathway
KAM339_029250	COG0348	domain, Protein
KAM339_029260	COG0437	4 iron, 4 sulfur cluster binding
KAM339_029270	COG0243	molybdopterin cofactor binding
KAM339_029290	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KAM339_029290	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
KAM339_029300	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KAM339_029310	COG3850	Histidine kinase
KAM339_029320	COG2197	response regulator
KAM339_029370	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KAM339_029390	COG0121	glutamine amidotransferase
KAM339_029400	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KAM339_029410	COG1960	acyl-CoA dehydrogenase activity
KAM339_029420	COG3437	response regulator, receiver
KAM339_029420	COG0784	Response regulator, receiver
KAM339_029440	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KAM339_029450	COG0328	RNA-DNA hybrid ribonuclease activity
KAM339_029460	COG2226	methyltransferase
KAM339_029470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KAM339_029480	COG0741	lytic transglycosylase activity
KAM339_029480	COG1388	LysM domain
KAM339_029510	COG1607	acyl-coa hydrolase
KAM339_029540	COG0741	lytic transglycosylase activity
KAM339_029560	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KAM339_029580	COG2911	Protein conserved in bacteria
KAM339_029590	COG0729	surface antigen
KAM339_029610	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KAM339_029630	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KAM339_029640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KAM339_029650	COG4134	Bacterial extracellular solute-binding protein
KAM339_029670	COG4136	ATPase activity
KAM339_029680	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KAM339_029690	COG2951	lytic endotransglycosylase activity
KAM339_029700	COG1846	Transcriptional regulator
KAM339_029720	COG0033	Phosphoglucomutase
KAM339_029730	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
KAM339_029750	COG0596	Alpha beta hydrolase
KAM339_029780	COG0716	FMN binding
KAM339_029800	COG0735	belongs to the Fur family
KAM339_029810	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KAM339_029830	COG1263	PTS System
KAM339_029830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM339_029830	COG2190	(PTS) system
KAM339_029840	COG0363	glucosamine-6-phosphate deaminase activity
KAM339_029850	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KAM339_029860	COG1846	Transcriptional regulator
KAM339_029860	COG1940	carbohydrate kinase activity
KAM339_029880	COG2194	sulfuric ester hydrolase activity
KAM339_029890	COG0217	transcriptional regulatory protein
KAM339_029900	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KAM339_029910	COG1801	Protein of unknown function DUF72
KAM339_029920	COG4106	trans-aconitate 2-methyltransferase activity
KAM339_029930	COG0500	methyltransferase
KAM339_029970	COG0583	DNA-binding transcription factor activity
KAM339_029980	COG0791	NLP P60 protein
KAM339_030010	COG1309	transcriptional regulator
KAM339_030080	COG0534	Mate efflux family protein
KAM339_030100	COG2841	Protein conserved in bacteria
KAM339_030110	COG0674	pyruvate-flavodoxin oxidoreductase activity
KAM339_030110	COG1013	pyruvate-flavodoxin oxidoreductase activity
KAM339_030110	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KAM339_030110	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KAM339_030130	COG0633	Ferredoxin
KAM339_030130	COG3217	Mosc domain protein beta barrel domain protein
KAM339_030130	COG0633	Ferredoxin
KAM339_030130	COG3217	Mosc domain protein beta barrel domain protein
KAM339_030140	COG0501	Belongs to the peptidase M48B family
KAM339_030150	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KAM339_030160	COG1073	alpha beta
KAM339_030160	COG2226	methyltransferase
KAM339_030170	COG0156	8-amino-7-oxononanoate synthase activity
KAM339_030180	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KAM339_030230	COG0017	Asparaginyl-tRNA synthetase
KAM339_030240	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KAM339_030270	COG1473	amidohydrolase
KAM339_030280	COG3069	C4-dicarboxylate transmembrane transporter activity
KAM339_030310	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM339_030340	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM339_030350	COG1393	Belongs to the ArsC family
KAM339_030360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KAM339_030370	COG1876	peptidase activity
KAM339_030390	COG3263	regulation of cellular component size
KAM339_030410	COG1280	lysine exporter protein (LysE YggA)
KAM339_030470	COG1957	nucleoside hydrolase
KAM339_030480	COG0564	pseudouridine synthase activity
KAM339_030500	COG1454	alcohol dehydrogenase
KAM339_030510	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAM339_030520	COG0702	epimerase
KAM339_030530	COG2914	Belongs to the UPF0125 (RnfH) family
KAM339_030540	COG2867	negative regulation of translational initiation
KAM339_030550	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KAM339_030580	COG3153	acetyltransferase
KAM339_030640	COG0259	pyridoxamine-phosphate oxidase activity
KAM339_030670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KAM339_030670	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KAM339_030680	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KAM339_030710	COG0457	Tetratricopeptide repeat
KAM339_030730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KAM339_030740	COG1138	Cytochrome C-type biogenesis protein
KAM339_030750	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KAM339_030760	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KAM339_030770	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KAM339_030780	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KAM339_030810	COG0835	chemotaxis
KAM339_030830	COG1192	Involved in chromosome partitioning
KAM339_030840	COG1360	Flagellar Motor Protein
KAM339_030850	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KAM339_030860	COG2201	protein-glutamate methylesterase activity
KAM339_030870	COG0784	Response regulator, receiver
KAM339_030870	COG2198	Histidine kinase
KAM339_030870	COG0643	Histidine kinase
KAM339_030880	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KAM339_030930	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KAM339_030950	COG1684	flagellar biosynthetic protein fliR
KAM339_031060	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KAM339_031080	COG1677	Flagellar hook-basal body complex protein FliE
KAM339_031110	COG1393	Belongs to the ArsC family
KAM339_031120	COG0798	PFAM Bile acid sodium symporter
KAM339_031130	COG0640	Transcriptional regulator
KAM339_031160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KAM339_031190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAM339_031200	COG0444	Belongs to the ABC transporter superfamily
KAM339_031210	COG4608	Belongs to the ABC transporter superfamily
KAM339_031230	COG2971	BadF BadG BcrA BcrD
KAM339_031250	COG0840	transmembrane signaling receptor activity
KAM339_031290	COG3724	N-succinylarginine dihydrolase activity
KAM339_031300	COG0616	signal peptide processing
KAM339_031310	COG1028	Short-chain dehydrogenase reductase Sdr
KAM339_031320	COG0583	DNA-binding transcription factor activity
KAM339_031340	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KAM339_031360	COG0583	DNA-binding transcription factor activity
KAM339_031370	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KAM339_031390	COG1881	PFAM PEBP family protein
KAM339_031410	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
KAM339_031410	COG3408	Glycogen debranching enzyme
KAM339_031420	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KAM339_031430	COG0739	heme binding
KAM339_031440	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KAM339_031470	COG0251	oxidation-reduction process
KAM339_031490	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KAM339_031510	COG3091	SprT-like family
KAM339_031530	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KAM339_031540	COG0189	ligase activity
KAM339_031560	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KAM339_031570	COG0583	DNA-binding transcription factor activity
KAM339_031600	COG1115	amino acid carrier protein
KAM339_031610	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KAM339_031640	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KAM339_031660	COG1301	dicarboxylic acid transport
KAM339_031670	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KAM339_031680	COG2912	Transglutaminase-like superfamily
KAM339_031700	COG2890	protein-(glutamine-N5) methyltransferase activity
KAM339_031710	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KAM339_031720	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KAM339_031730	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KAM339_031740	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KAM339_031750	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KAM339_031760	COG0193	aminoacyl-tRNA hydrolase activity
KAM339_031770	COG0012	GTP binding
KAM339_031780	COG0471	metal ion transport
KAM339_031780	COG0490	domain, Protein
KAM339_031800	COG0657	acetylesterase activity
KAM339_031830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAM339_031860	COG1012	belongs to the aldehyde dehydrogenase family
KAM339_031880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KAM339_031910	COG0180	Tryptophanyl-tRNA synthetase
KAM339_031920	COG0546	phosphoglycolate phosphatase activity
KAM339_031930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KAM339_031940	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KAM339_031960	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KAM339_031970	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KAM339_032030	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KAM339_032040	COG0583	DNA-binding transcription factor activity
KAM339_032070	COG0583	DNA-binding transcription factor activity
KAM339_032100	COG3121	Chaperone
KAM339_032110	COG3188	usher protein
KAM339_032120	COG3121	Chaperone
KAM339_032140	COG0739	heme binding
KAM339_032160	COG1511	domain protein
KAM339_032160	COG3264	Mechanosensitive ion channel
KAM339_032170	COG0584	glycerophosphoryl diester phosphodiesterase
KAM339_032190	COG1053	succinate dehydrogenase
KAM339_032200	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KAM339_032210	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
KAM339_032220	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
KAM339_032250	COG3214	Protein conserved in bacteria
KAM339_032260	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KAM339_032300	COG0300	oxidoreductase activity
KAM339_032340	COG0189	ligase activity
KAM339_032340	COG4067	protein conserved in archaea
KAM339_032350	COG0516	GMP reductase activity
KAM339_032370	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KAM339_032380	COG2011	ABC-type metal ion transport system permease component
KAM339_032390	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KAM339_032400	COG1464	Belongs to the NlpA lipoprotein family
KAM339_032430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KAM339_032450	COG2199	diguanylate cyclase activity
KAM339_032480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAM339_032510	COG1335	isochorismatase
KAM339_032520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KAM339_032530	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KAM339_032540	COG1702	phosphate starvation-inducible protein PhoH
KAM339_032550	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KAM339_032560	COG4535	Mg2 and Co2 transporter CorC
KAM339_032570	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KAM339_032580	COG2888	peptidyl-tyrosine sulfation
KAM339_032590	COG0495	leucyl-tRNA aminoacylation
KAM339_032620	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KAM339_032630	COG0799	negative regulation of ribosome biogenesis
KAM339_032640	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KAM339_032650	COG0768	penicillin binding
KAM339_032660	COG0772	Belongs to the SEDS family
KAM339_032670	COG2951	lytic endotransglycosylase activity
KAM339_032680	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KAM339_032690	COG1686	Belongs to the peptidase S11 family
KAM339_032700	COG2921	Belongs to the UPF0250 family
KAM339_032710	COG0321	lipoyl(octanoyl) transferase activity
KAM339_032720	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KAM339_032740	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM339_032770	COG0789	Transcriptional regulator
KAM339_032780	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KAM339_032800	COG1970	mechanosensitive ion channel activity
KAM339_032810	COG4974	Belongs to the 'phage' integrase family
KAM339_032830	COG0312	modulator of DNA gyrase
KAM339_032840	COG0312	modulator of DNA gyrase
KAM339_032870	COG0826	peptidase U32
KAM339_032880	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KAM339_032890	COG1422	Protein of unknown function (DUF1090)
KAM339_032900	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KAM339_032910	COG2211	Major facilitator Superfamily
KAM339_032920	COG1185	polyribonucleotide nucleotidyltransferase activity
KAM339_032930	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KAM339_032940	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KAM339_032950	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KAM339_032960	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KAM339_032970	COG0195	Participates in both transcription termination and antitermination
KAM339_032980	COG0779	Required for maturation of 30S ribosomal subunits
KAM339_032990	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KAM339_033000	COG0149	triose-phosphate isomerase activity
KAM339_033020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KAM339_033030	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KAM339_033050	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KAM339_033060	COG1534	Rna-binding protein
KAM339_033090	COG1360	Flagellar Motor Protein
KAM339_033100	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KAM339_033110	COG1722	exodeoxyribonuclease VII activity
KAM339_033120	COG0142	geranyltranstransferase activity
KAM339_033130	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KAM339_033140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAM339_033150	COG0601	transmembrane transport
KAM339_033170	COG4172	Belongs to the ABC transporter superfamily
KAM339_033180	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KAM339_033190	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KAM339_033200	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KAM339_033210	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KAM339_033240	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KAM339_033240	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KAM339_033250	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KAM339_033270	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KAM339_033290	COG3381	protein complex oligomerization
KAM339_033320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KAM339_033330	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KAM339_033340	COG0511	ligase activity, forming carbon-carbon bonds
KAM339_033350	COG0439	Biotin carboxylase
KAM339_033360	COG3924	membrane
KAM339_033370	COG4145	pantothenate transmembrane transporter activity
KAM339_033380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM339_033380	COG1263	PTS System
KAM339_033380	COG2190	(PTS) system
KAM339_033390	COG0583	DNA-binding transcription factor activity
KAM339_033400	COG0604	alcohol dehydrogenase
KAM339_033410	COG2264	protein methyltransferase activity
KAM339_033420	COG0110	maltose O-acetyltransferase activity
KAM339_033440	COG0778	Nitroreductase
KAM339_033450	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAM339_033450	COG1902	pentaerythritol trinitrate reductase activity
KAM339_033460	COG0616	signal peptide processing
KAM339_033500	COG3139	Protein of unknown function (DUF1315)
KAM339_033510	COG0252	asparaginase activity
KAM339_033520	COG0786	glutamate:sodium symporter activity
KAM339_033540	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KAM339_033550	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KAM339_033560	COG0384	phenazine biosynthesis protein PhzF
KAM339_033570	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KAM339_033580	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KAM339_033590	COG0175	sulfate reduction
KAM339_033600	COG2113	Glycine betaine
KAM339_033610	COG4176	ABC-type proline glycine betaine transport system permease component
KAM339_033620	COG4175	Glycine betaine
KAM339_033640	COG3610	response to peptide
KAM339_033650	COG2966	Psort location CytoplasmicMembrane, score
KAM339_033670	COG0521	Mo-molybdopterin cofactor biosynthetic process
KAM339_033710	COG2313	pseudouridylate synthase activity
KAM339_033720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM339_033730	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KAM339_033730	COG2146	nitrite reductase [NAD(P)H] activity
KAM339_033740	COG2146	nitrite reductase [NAD(P)H] activity
KAM339_033740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KAM339_033750	COG1116	anion transmembrane transporter activity
KAM339_033760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KAM339_033770	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KAM339_033770	COG1116	anion transmembrane transporter activity
KAM339_033800	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KAM339_033800	COG1648	precorrin-2 dehydrogenase activity
KAM339_033810	COG0243	molybdopterin cofactor binding
KAM339_033860	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KAM339_033890	COG1073	alpha beta
KAM339_033900	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
KAM339_033910	COG2195	Cleaves the N-terminal amino acid of tripeptides
KAM339_033930	COG4608	Belongs to the ABC transporter superfamily
KAM339_033940	COG0444	Belongs to the ABC transporter superfamily
KAM339_033960	COG4239	(ABC) transporter, permease
KAM339_033970	COG4174	ABC transporter (Permease)
KAM339_033980	COG4206	TonB-dependent receptor
KAM339_034000	COG0811	peptide transport
KAM339_034010	COG0811	peptide transport
KAM339_034020	COG0848	biopolymer transport protein
KAM339_034080	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KAM339_034090	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KAM339_034100	COG0840	transmembrane signaling receptor activity
KAM339_034120	COG1278	Cold shock
KAM339_034130	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KAM339_034140	COG1162	GTPase activity
KAM339_034150	COG0688	phosphatidylethanolamine metabolic process
KAM339_034160	COG4628	conserved protein (DUF2132)
KAM339_034190	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KAM339_034200	COG2207	Transcriptional regulator
KAM339_034220	COG5001	Diguanylate cyclase
KAM339_034220	COG3300	MHYT domain
KAM339_034230	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
KAM339_034240	COG5001	Diguanylate cyclase
KAM339_034240	COG4251	negative regulation of phosphorylation
KAM339_034240	COG2203	Gaf domain
KAM339_034240	COG3706	GGDEF domain
KAM339_034250	COG3039	Transposase
KAM339_034320	COG4974	Belongs to the 'phage' integrase family
KAM339_034340	COG5002	protein histidine kinase activity
KAM339_034340	COG5001	Diguanylate cyclase
KAM339_034340	COG3447	MASE1 domain protein
KAM339_034380	COG0582	viral genome integration into host DNA
KAM339_034410	COG1132	(ABC) transporter
KAM339_034430	COG2897	thiosulfate sulfurtransferase activity
KAM339_034440	COG2066	Belongs to the glutaminase family
KAM339_034450	COG3171	Protein conserved in bacteria
KAM339_034460	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KAM339_034470	COG4935	Belongs to the peptidase S8 family
KAM339_034470	COG2234	aminopeptidase activity
KAM339_034480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KAM339_034490	COG2200	EAL domain
KAM339_034500	COG1090	epimerase
KAM339_034510	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KAM339_034520	COG4181	ATPase activity
KAM339_034530	COG2755	lipolytic protein G-D-S-L family
KAM339_034540	COG0835	chemotaxis
KAM339_034540	COG0784	Response regulator, receiver
KAM339_034560	COG0516	GMP reductase activity
KAM339_034560	COG0517	IMP dehydrogenase activity
KAM339_034570	COG0488	(ABC) transporter
KAM339_034590	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KAM339_034670	COG0789	Transcriptional regulator
KAM339_034690	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KAM339_034730	COG0668	transmembrane transport
KAM339_034750	COG2731	YhcH YjgK YiaL family protein
KAM339_034770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KAM339_034780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KAM339_034790	COG3227	Zinc metalloprotease (Elastase)
KAM339_034800	COG0583	DNA-binding transcription factor activity
KAM339_034810	COG0477	Major facilitator Superfamily
KAM339_034860	COG2985	domain, Protein
KAM339_034860	COG0569	domain protein
KAM339_034870	COG1272	protein, Hemolysin III
KAM339_034880	COG0076	glutamate decarboxylase activity
KAM339_034890	COG2917	probably involved in intracellular septation
KAM339_034900	COG2350	Protein conserved in bacteria
KAM339_034920	COG1555	photosystem II stabilization
KAM339_034930	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KAM339_034940	COG3104	oligopeptide transport
KAM339_034950	COG0745	RESPONSE REGULATOR receiver
KAM339_035010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM339_035030	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KAM339_035040	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KAM339_035060	COG0316	Belongs to the HesB IscA family
KAM339_035080	COG0038	chloride channel
KAM339_035090	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KAM339_035120	COG0671	phosphoesterase, PA-phosphatase related
KAM339_035140	COG0583	DNA-binding transcription factor activity
KAM339_035150	COG2076	Multidrug Resistance protein
KAM339_035170	COG0346	lactoylglutathione lyase activity
KAM339_035180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KAM339_035190	COG1643	Atp-dependent helicase
KAM339_035210	COG1489	DNA binding
KAM339_035220	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KAM339_035230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KAM339_035250	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KAM339_035260	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KAM339_035270	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KAM339_035290	COG0842	Transport permease protein
KAM339_035300	COG1131	(ABC) transporter
KAM339_035330	COG0163	prenyltransferase activity
KAM339_035340	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KAM339_035350	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KAM339_035380	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
KAM339_035410	COG1136	(ABC) transporter
KAM339_035520	COG0529	Catalyzes the synthesis of activated sulfate
KAM339_035530	COG3273	potassium ion transport
KAM339_035530	COG0471	metal ion transport
KAM339_035540	COG2895	sulfate adenylyltransferase (ATP) activity
KAM339_035550	COG0175	sulfate reduction
KAM339_035560	COG1648	precorrin-2 dehydrogenase activity
KAM339_035560	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KAM339_035570	COG0330	HflC and HflK could
KAM339_035580	COG1585	Membrane protein implicated in regulation of membrane protease activity
KAM339_035610	COG0673	inositol 2-dehydrogenase activity
KAM339_035630	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KAM339_035640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KAM339_035650	COG3036	rescue of stalled ribosome
KAM339_035680	COG0138	bifunctional purine biosynthesis protein purh
KAM339_035690	COG0151	Belongs to the GarS family
KAM339_035740	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KAM339_035750	COG0358	DNA primase activity
KAM339_035760	COG1610	YqeY-like protein
KAM339_035770	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KAM339_035780	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KAM339_035810	COG1388	LysM domain
KAM339_035810	COG4942	peptidase
KAM339_035820	COG1238	metal cluster binding
KAM339_035830	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KAM339_035840	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KAM339_035850	COG0585	pseudouridine synthase activity
KAM339_035870	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KAM339_035880	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KAM339_035890	COG0148	phosphopyruvate hydratase activity
KAM339_035900	COG0504	CTP synthase activity
KAM339_035910	COG3956	TIGRFAM MazG family protein
KAM339_035920	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KAM339_035930	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KAM339_035950	COG4807	Protein conserved in bacteria
KAM339_035960	COG3023	N-Acetylmuramoyl-L-alanine amidase
KAM339_035970	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KAM339_035980	COG1381	Involved in DNA repair and RecF pathway recombination
KAM339_036000	COG0571	ribonuclease III activity
KAM339_036010	COG0681	Belongs to the peptidase S26 family
KAM339_036020	COG0481	GTPase activity
KAM339_036050	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
KAM339_036060	COG1595	DNA-templated transcription, initiation
KAM339_036070	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KAM339_036090	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KAM339_036110	COG0583	DNA-binding transcription factor activity
KAM339_036170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAM339_036190	COG0126	phosphoglycerate kinase activity
KAM339_036200	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KAM339_036210	COG1940	carbohydrate kinase activity
KAM339_036220	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KAM339_036230	COG2816	NAD+ diphosphatase activity
KAM339_036240	COG4991	sh3 domain protein
KAM339_036250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KAM339_036280	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KAM339_036290	COG1028	Short-chain dehydrogenase reductase Sdr
KAM339_036310	COG1505	serine-type exopeptidase activity
KAM339_036320	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KAM339_036330	COG0765	amino acid transport
KAM339_036340	COG0765	amino acid transport
KAM339_036350	COG1126	abc transporter atp-binding protein
KAM339_036360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM339_036370	COG3174	membrane
KAM339_036380	COG0110	maltose O-acetyltransferase activity
KAM339_036440	COG1942	4-Oxalocrotonate Tautomerase
KAM339_036450	COG0583	DNA-binding transcription factor activity
KAM339_036460	COG0165	Argininosuccinate lyase
KAM339_036470	COG0137	argininosuccinate synthase activity
KAM339_036490	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KAM339_036500	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KAM339_036520	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KAM339_036540	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KAM339_036610	COG0583	DNA-binding transcription factor activity
KAM339_036620	COG1380	Effector of murein hydrolase LrgA
KAM339_036630	COG1346	cytolysis
KAM339_036640	COG0460	homoserine dehydrogenase
KAM339_036640	COG0527	aspartate kinase activity
KAM339_036650	COG0626	cystathionine gamma-synthase activity
KAM339_036680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM339_036690	COG0814	amino acid
KAM339_036700	COG1218	3'(2'),5'-bisphosphate nucleotidase
KAM339_036710	COG0494	nUDIX hydrolase
KAM339_036720	COG1011	Hydrolase
KAM339_036730	COG1902	pentaerythritol trinitrate reductase activity
KAM339_036750	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KAM339_036780	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
KAM339_036800	COG3156	type II secretion system protein K
KAM339_036810	COG4795	General secretion pathway protein
KAM339_036820	COG2165	general secretion pathway protein
KAM339_036840	COG2165	general secretion pathway protein
KAM339_036850	COG1459	type II secretion system
KAM339_036860	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KAM339_036880	COG3031	protein transport across the cell outer membrane
KAM339_036900	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KAM339_036910	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KAM339_036940	COG0456	acetyltransferase
KAM339_036950	COG3133	Outer membrane lipoprotein
KAM339_036960	COG3025	triphosphatase activity
KAM339_036970	COG1392	Phosphate transport regulator
KAM339_036980	COG0306	phosphate transporter
KAM339_036990	COG0617	tRNA 3'-terminal CCA addition
KAM339_037000	COG3267	Type II secretory pathway component ExeA
KAM339_037000	COG3409	Peptidoglycan-binding domain 1 protein
KAM339_037020	COG1194	a g-specific adenine glycosylase
KAM339_037030	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
KAM339_037060	COG3240	lipase activity
KAM339_037080	COG3009	Protein conserved in bacteria
KAM339_037090	COG3008	intermembrane lipid transfer
KAM339_037090	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KAM339_037100	COG2995	paraquat-inducible protein a
KAM339_037120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAM339_037130	COG3706	GGDEF domain
KAM339_037130	COG5001	Diguanylate cyclase
KAM339_037130	COG2203	Gaf domain
KAM339_037130	COG4251	negative regulation of phosphorylation
KAM339_037140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KAM339_037150	COG2813	Specifically methylates the guanine in position
KAM339_037160	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KAM339_037170	COG0297	glycogen (starch) synthase activity
KAM339_037200	COG1757	Na H antiporter
KAM339_037210	COG0583	DNA-binding transcription factor activity
KAM339_037220	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KAM339_037230	COG3842	ATPase activity
KAM339_037240	COG1176	ABC-type spermidine putrescine transport system, permease component I
KAM339_037250	COG1177	transmembrane transport
KAM339_037260	COG1012	belongs to the aldehyde dehydrogenase family
KAM339_037270	COG0109	protoheme IX farnesyltransferase activity
KAM339_037330	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KAM339_037350	COG1565	acr, cog1565
KAM339_037350	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KAM339_037360	COG1444	tRNA N-acetyltransferase activity
KAM339_037400	COG1803	Methylglyoxal synthase
KAM339_037430	COG0252	asparaginase activity
KAM339_037470	COG1263	PTS System
KAM339_037470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM339_037480	COG0366	Alpha amylase catalytic
KAM339_037490	COG0110	maltose O-acetyltransferase activity
KAM339_037500	COG1522	sequence-specific DNA binding
KAM339_037560	COG3068	Protein conserved in bacteria
KAM339_037580	COG0739	heme binding
KAM339_037620	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
KAM339_037630	COG1121	(ABC) transporter
KAM339_037640	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KAM339_037650	COG0583	DNA-binding transcription factor activity
KAM339_037670	COG1573	uracil-dna glycosylase
KAM339_037680	COG2962	Rard protein
KAM339_037690	COG2827	Endonuclease containing a URI domain
KAM339_037720	COG1842	Phage shock protein A
KAM339_037730	COG0204	Acyl-transferase
KAM339_037770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KAM339_037790	COG0484	heat shock protein binding
KAM339_037900	COG1289	transmembrane transporter activity
KAM339_037910	COG1566	PFAM secretion protein HlyD family protein
KAM339_037940	COG1051	belongs to the nudix hydrolase family
KAM339_037950	COG3150	esterase
KAM339_037970	COG3151	Protein conserved in bacteria
KAM339_037980	COG0494	nUDIX hydrolase
KAM339_037990	COG1538	Outer membrane efflux protein
KAM339_038000	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KAM339_038000	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KAM339_038010	COG1560	Kdo2-lipid A biosynthetic process
KAM339_038040	COG2771	luxR family
KAM339_038050	COG3916	Acyl-homoserine-lactone synthase
KAM339_038070	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
KAM339_038080	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM339_038080	COG2213	PTS system mannitol-specific
KAM339_038090	COG0246	Mannitol dehydrogenase
KAM339_038100	COG3722	fumarate hydratase activity
KAM339_038110	COG3263	regulation of cellular component size
KAM339_038150	COG1671	Belongs to the UPF0178 family
KAM339_038180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KAM339_038190	COG0513	Belongs to the DEAD box helicase family
KAM339_038230	COG1575	Belongs to the MenA family. Type 1 subfamily
KAM339_038240	COG1169	isochorismate synthase
KAM339_038250	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KAM339_038260	COG0596	Alpha beta hydrolase
KAM339_038270	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KAM339_038290	COG0318	PFAM AMP-dependent synthetase and ligase
KAM339_038300	COG3291	Pkd domain containing protein
KAM339_038310	COG2949	membrane
KAM339_038320	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KAM339_038340	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KAM339_038400	COG2873	o-acetylhomoserine
KAM339_038420	COG1979	alcohol dehydrogenase
KAM339_038450	COG4221	oxidoreductase activity
KAM339_038490	COG1285	pathogenesis
KAM339_038520	COG1368	sulfuric ester hydrolase activity
KAM339_038530	COG1522	sequence-specific DNA binding
KAM339_038550	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KAM339_038570	COG1546	Belongs to the CinA family
KAM339_038570	COG1058	Belongs to the CinA family
KAM339_038580	COG1988	membrane-bound metal-dependent
KAM339_038600	COG0561	phosphatase activity
KAM339_038610	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KAM339_038630	COG1011	Hydrolase
KAM339_038660	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KAM339_038670	COG0019	diaminopimelate decarboxylase activity
KAM339_038690	COG1965	Belongs to the frataxin family
KAM339_038700	COG0400	carboxylic ester hydrolase activity
KAM339_038710	COG3072	Adenylate cyclase
KAM339_038720	COG0181	hydroxymethylbilane synthase activity
KAM339_038740	COG2959	enzyme of heme biosynthesis
KAM339_038750	COG3071	HemY protein
KAM339_038770	COG0312	modulator of DNA gyrase
KAM339_038780	COG3028	Belongs to the UPF0307 family
KAM339_038800	COG2926	Belongs to the UPF0265 family
KAM339_038820	COG1396	sequence-specific DNA binding
KAM339_038830	COG3135	benzoate transporter
KAM339_038890	COG3047	cAMP biosynthetic process
KAM339_038900	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KAM339_038910	COG2197	response regulator
KAM339_038960	COG1278	Cold shock
KAM339_039020	COG3706	GGDEF domain
KAM339_039030	COG0347	Belongs to the P(II) protein family
KAM339_039040	COG0004	ammonium transporteR
KAM339_039060	COG0346	lactoylglutathione lyase activity
KAM339_039090	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KAM339_039100	COG1074	ATP-dependent DNA helicase activity
KAM339_039110	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KAM339_039120	COG2259	Doxx family
KAM339_039130	COG1741	Belongs to the pirin family
KAM339_039150	COG0583	DNA-binding transcription factor activity
KAM339_039200	COG1175	transmembrane transport
KAM339_039220	COG3842	ATPase activity
KAM339_039280	COG0456	acetyltransferase
KAM339_039290	COG0753	catalase activity
KAM339_039330	COG0494	nUDIX hydrolase
KAM339_039340	COG0628	permease
KAM339_039360	COG2957	Belongs to the agmatine deiminase family
KAM339_039390	COG2957	Belongs to the agmatine deiminase family
KAM339_039400	COG0583	DNA-binding transcription factor activity
KAM339_039430	COG1461	Dihydroxyacetone kinase
KAM339_039440	COG2376	Dihydroxyacetone kinase
KAM339_039450	COG2252	PERMEase
KAM339_039460	COG1484	DNA-dependent DNA replication
KAM339_039470	COG4584	PFAM Integrase catalytic
KAM339_039480	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KAM339_039490	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KAM339_039500	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KAM339_039510	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KAM339_039520	COG0049	tRNA binding
KAM339_039530	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KAM339_039540	COG2168	tRNA wobble position uridine thiolation
KAM339_039560	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KAM339_039570	COG0251	oxidation-reduction process
KAM339_039580	COG2964	Protein conserved in bacteria
KAM339_039590	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KAM339_039600	COG0085	RNA polymerase activity
KAM339_039610	COG0222	ribosome binding
KAM339_039620	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KAM339_039630	COG0081	regulation of translation
KAM339_039640	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KAM339_039650	COG0250	Participates in transcription elongation, termination and antitermination
KAM339_039670	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KAM339_039700	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KAM339_039710	COG0569	domain protein
KAM339_039720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KAM339_039730	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KAM339_039740	COG3005	denitrification pathway
KAM339_039750	COG0243	molybdopterin cofactor binding
KAM339_039820	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KAM339_039840	COG2204	response regulator
KAM339_039860	COG2205	protein histidine kinase activity
KAM339_039890	COG0516	GMP reductase activity
KAM339_039890	COG0517	IMP dehydrogenase activity
KAM339_039910	COG1522	sequence-specific DNA binding
KAM339_039920	COG2502	aspartate--ammonia ligase
KAM339_039930	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KAM339_039940	COG0542	response to heat
KAM339_039960	COG0564	pseudouridine synthase activity
KAM339_039970	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAM339_039980	COG3681	Belongs to the UPF0597 family
KAM339_039990	COG2964	Protein conserved in bacteria
KAM339_040000	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KAM339_040010	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KAM339_040020	COG1979	alcohol dehydrogenase
KAM339_040030	COG2207	Transcriptional regulator
KAM339_040040	COG3040	lipid binding
KAM339_040080	COG0583	DNA-binding transcription factor activity
KAM339_040110	COG0540	Belongs to the ATCase OTCase family
KAM339_040120	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
KAM339_040130	COG1438	arginine binding
KAM339_040140	COG1288	antiporter activity
KAM339_040150	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KAM339_040230	COG3250	beta-galactosidase activity
KAM339_040250	COG1609	Transcriptional regulator
KAM339_040260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KAM339_040280	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KAM339_040290	COG2017	converts alpha-aldose to the beta-anomer
KAM339_040300	COG0667	Aldo Keto reductase
KAM339_040310	COG1968	undecaprenyl-diphosphatase activity
KAM339_040320	COG3806	Anti-sigma factor
KAM339_040330	COG1595	DNA-templated transcription, initiation
KAM339_040370	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KAM339_040380	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KAM339_040390	COG0477	Major facilitator Superfamily
KAM339_040420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM339_040430	COG1131	(ABC) transporter
KAM339_040440	COG0842	Transport permease protein
KAM339_040450	COG0842	Transport permease protein
KAM339_040460	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KAM339_040480	COG2116	formate transmembrane transporter activity
KAM339_040490	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KAM339_040490	COG1648	precorrin-2 dehydrogenase activity
KAM339_040500	COG2239	Acts as a magnesium transporter
KAM339_040510	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KAM339_040520	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KAM339_040540	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KAM339_040560	COG0514	ATP-dependent DNA helicase (RecQ)
KAM339_040570	COG2050	protein possibly involved in aromatic compounds catabolism
KAM339_040590	COG2258	MOSC domain
KAM339_040600	COG1177	transmembrane transport
KAM339_040610	COG1176	ABC-type spermidine putrescine transport system, permease component I
KAM339_040620	COG3842	ATPase activity
KAM339_040660	COG0174	glutamine synthetase
KAM339_040700	COG3045	CreA protein
KAM339_040710	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KAM339_040720	COG0443	Heat shock 70 kDa protein
KAM339_040750	COG0366	Alpha amylase catalytic
KAM339_040780	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KAM339_040790	COG0745	RESPONSE REGULATOR receiver
KAM339_040800	COG2205	protein histidine kinase activity
KAM339_040820	COG0281	malic enzyme
KAM339_040830	COG0702	epimerase
KAM339_040840	COG0254	rRNA binding
KAM339_040850	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KAM339_040860	COG1309	transcriptional regulator
KAM339_040900	COG0129	dihydroxy-acid dehydratase activity
KAM339_040920	COG3978	acetolactate synthase activity
KAM339_040940	COG0606	chelatase, subunit chli
KAM339_040950	COG0204	Acyl-transferase
KAM339_040960	COG0204	Acyl-transferase
KAM339_040970	COG1683	Conserved Protein
KAM339_040990	COG1335	isochorismatase
KAM339_041010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KAM339_041020	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KAM339_041040	COG3084	Protein conserved in bacteria
KAM339_041050	COG3706	GGDEF domain
KAM339_041050	COG5001	Diguanylate cyclase
KAM339_041050	COG4251	negative regulation of phosphorylation
KAM339_041050	COG2203	Gaf domain
KAM339_041080	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KAM339_041090	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KAM339_041100	COG1561	YicC-like family, N-terminal region
KAM339_041170	COG2801	Transposase and inactivated derivatives
KAM339_041180	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KAM339_041190	COG1518	maintenance of DNA repeat elements
KAM339_041220	COG1857	crispr-associated protein
KAM339_041290	COG1519	Transferase
KAM339_041300	COG0859	PFAM glycosyl transferase family 9
KAM339_041310	COG0463	Glycosyl transferase, family 2
KAM339_041320	COG0859	PFAM glycosyl transferase family 9
KAM339_041330	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KAM339_041340	COG2990	Protein conserved in bacteria
KAM339_041350	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KAM339_041370	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KAM339_041380	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KAM339_041390	COG2003	Belongs to the UPF0758 family
KAM339_041400	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KAM339_041410	COG0756	dUTP diphosphatase activity
KAM339_041420	COG1309	transcriptional regulator
KAM339_041440	COG0668	transmembrane transport
KAM339_041460	COG0166	Belongs to the GPI family
KAM339_041480	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KAM339_041490	COG0583	DNA-binding transcription factor activity
KAM339_041510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KAM339_041510	COG1042	CoA-binding domain protein
KAM339_041510	COG0045	succinate-CoA ligase (ADP-forming) activity
KAM339_041520	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
KAM339_041530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KAM339_041540	COG1739	Uncharacterized protein family UPF0029
KAM339_041550	COG0006	proline dipeptidase activity
KAM339_041560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KAM339_041570	COG1024	Enoyl-CoA hydratase
KAM339_041570	COG1250	3-hydroxyacyl-CoA dehydrogenase
KAM339_041580	COG0183	Belongs to the thiolase family
KAM339_041630	COG0425	Belongs to the sulfur carrier protein TusA family
KAM339_041640	COG0251	oxidation-reduction process
KAM339_041660	COG2885	chlorophyll binding
KAM339_041680	COG1335	isochorismatase
KAM339_041690	COG2818	Glycosylase
KAM339_041700	COG0752	glycyl-tRNA synthetase alpha subunit
KAM339_041710	COG0751	glycine-tRNA ligase activity
KAM339_041760	COG0814	amino acid
KAM339_041770	COG0814	amino acid
KAM339_041780	COG3033	Beta-eliminating lyase
KAM339_041790	COG0348	domain, Protein
KAM339_041810	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAM339_041820	COG0426	domain, Protein
KAM339_041820	COG1773	rubredoxin
KAM339_041830	COG3604	Transcriptional regulator
KAM339_041840	COG1609	Transcriptional regulator
KAM339_041920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KAM339_041950	COG2960	long-chain fatty acid transporting porin activity
KAM339_041970	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KAM339_042000	COG3118	belongs to the thioredoxin family
KAM339_042010	COG0513	Belongs to the DEAD box helicase family
KAM339_042020	COG0248	Ppx GppA phosphatase
KAM339_042040	COG0742	ribosomal rna small subunit methyltransferase
KAM339_042080	COG0084	hydrolase, TatD family'
KAM339_042090	COG0805	protein transport
KAM339_042100	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KAM339_042110	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KAM339_042120	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KAM339_042130	COG3165	ubiquinone biosynthetic process from chorismate
KAM339_042150	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KAM339_042160	COG0402	S-adenosylhomocysteine deaminase activity
KAM339_042170	COG1484	DNA-dependent DNA replication
KAM339_042180	COG4584	PFAM Integrase catalytic
KAM339_042190	COG0402	S-adenosylhomocysteine deaminase activity
KAM339_042210	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KAM339_042220	COG0848	biopolymer transport protein
KAM339_042230	COG0811	peptide transport
KAM339_042240	COG0811	peptide transport
KAM339_042260	COG2771	luxR family
KAM339_042270	COG5002	protein histidine kinase activity
KAM339_042270	COG2205	protein histidine kinase activity
KAM339_042270	COG0784	Response regulator, receiver
KAM339_042290	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KAM339_042300	COG1349	DNA-binding transcription factor activity
KAM339_042310	COG0745	RESPONSE REGULATOR receiver
KAM339_042320	COG2205	protein histidine kinase activity
KAM339_042340	COG4452	Inner membrane protein CreD
KAM339_042350	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KAM339_042360	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KAM339_042370	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KAM339_042380	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KAM339_042390	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KAM339_042400	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KAM339_042410	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KAM339_042430	COG0356	it plays a direct role in the translocation of protons across the membrane
KAM339_042450	COG1475	DNA binding
KAM339_042460	COG1192	Involved in chromosome partitioning
KAM339_042470	COG0357	Ribosomal RNA small subunit methyltransferase G
KAM339_042480	COG0445	tRNA wobble uridine modification
KAM339_042490	COG0716	FMN binding
KAM339_042500	COG4774	siderophore transport
KAM339_042510	COG4615	Cyclic peptide transporter
KAM339_042520	COG1120	ATPase activity
KAM339_042530	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KAM339_042550	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KAM339_042560	COG0706	membrane insertase activity
KAM339_042570	COG0594	ribonuclease P activity
KAM339_042580	COG1126	abc transporter atp-binding protein
KAM339_042670	COG1484	DNA-dependent DNA replication
KAM339_042680	COG4584	PFAM Integrase catalytic
KAM339_042690	COG2974	May be involved in recombination
KAM339_042700	COG3385	transposase activity
KAM339_042810	COG1525	nuclease
KAM339_042870	COG1192	Involved in chromosome partitioning
KAM339_042960	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KAM339_042970	COG1061	Type III restriction enzyme res subunit
KAM339_042980	COG1002	Type II restriction enzyme, methylase subunits
KAM339_043010	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KAM339_043280	COG3385	transposase activity
KAM339_043300	COG3385	transposase activity
KAM339_043310	COG0653	protein targeting
KAM339_043340	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KAM339_043420	COG0714	Associated with various cellular activities
KAM339_043550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KAM339_043690	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM339_043770	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM339_043780	COG3041	Addiction module toxin RelE StbE family
KAM339_043850	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM339_043920	COG2948	multi-organism process
KAM339_043940	COG0583	DNA-binding transcription factor activity
KAM339_043960	COG1846	Transcriptional regulator
KAM339_044000	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KAM339_044030	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KAM339_044060	COG0583	DNA-binding transcription factor activity
KAM339_044080	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KAM339_044090	COG0625	glutathione transferase activity
KAM339_044200	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KAM339_044220	COG0183	Belongs to the thiolase family
KAM339_044230	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KAM339_044470	COG1396	sequence-specific DNA binding
KAM339_044480	COG3550	peptidyl-serine autophosphorylation
KAM339_044500	COG4584	PFAM Integrase catalytic
KAM339_044510	COG1484	DNA-dependent DNA replication
KAM339_044630	COG5433	transposase activity
KAM339_044660	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KAM339_044750	COG3039	Transposase
KAM339_044770	COG1484	DNA-dependent DNA replication
KAM339_044780	COG4584	PFAM Integrase catalytic
KAM339_045030	COG0789	Transcriptional regulator
KAM339_045260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KAM339_045300	COG0346	lactoylglutathione lyase activity
KAM339_045640	COG3451	type IV secretory pathway VirB4
KAM339_045650	COG5268	conjugation
KAM339_045660	COG3838	Conjugal transfer protein Trbc
KAM339_045670	COG4962	Type ii secretion system protein e
KAM339_045710	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KAM339_045760	COG1525	nuclease
KAM339_045800	COG1192	Involved in chromosome partitioning
KAM339_045860	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM339_045890	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KAM339_045920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KAM339_045990	COG3039	Transposase
KAM339_046000	COG0840	transmembrane signaling receptor activity