locus-tag	class	description
KAM345_000010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KAM345_000020	COG0592	DNA-directed DNA polymerase activity
KAM345_000040	COG0187	DNA topoisomerase II activity
KAM345_000080	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KAM345_000110	COG3039	Transposase
KAM345_000130	COG1595	DNA-templated transcription, initiation
KAM345_000150	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
KAM345_000160	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KAM345_000200	COG3220	belongs to the UPF0276 family
KAM345_000230	COG3415	Transposase
KAM345_000230	COG2801	Transposase and inactivated derivatives
KAM345_000390	COG2207	Transcriptional regulator
KAM345_000400	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KAM345_000410	COG0071	Belongs to the small heat shock protein (HSP20) family
KAM345_000420	COG0071	Belongs to the small heat shock protein (HSP20) family
KAM345_000430	COG3977	Valine--pyruvate aminotransferase
KAM345_000460	COG2814	Major facilitator Superfamily
KAM345_000470	COG0745	RESPONSE REGULATOR receiver
KAM345_000480	COG2205	protein histidine kinase activity
KAM345_000520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KAM345_000530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM345_000530	COG4191	Histidine kinase
KAM345_000540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM345_000550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM345_000560	COG1309	transcriptional regulator
KAM345_000580	COG0561	phosphatase activity
KAM345_000590	COG2267	carboxylic ester hydrolase activity
KAM345_000600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KAM345_000610	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KAM345_000620	COG1758	RNA polymerase activity
KAM345_000640	COG0859	PFAM glycosyl transferase family 9
KAM345_000650	COG3642	lipopolysaccharide core region biosynthetic process
KAM345_000730	COG0589	response to stress
KAM345_000750	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KAM345_000760	COG3706	GGDEF domain
KAM345_000770	COG1528	Iron-storage protein
KAM345_000780	COG2081	HI0933 family
KAM345_000790	COG2223	nitrite transmembrane transporter activity
KAM345_000800	COG1280	lysine exporter protein (LysE YggA)
KAM345_000830	COG3188	usher protein
KAM345_000860	COG2197	response regulator
KAM345_000870	COG2205	protein histidine kinase activity
KAM345_000870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM345_000890	COG3275	phosphorelay sensor kinase activity
KAM345_000900	COG3279	Response regulator of the LytR AlgR family
KAM345_000910	COG2223	nitrite transmembrane transporter activity
KAM345_000930	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KAM345_000940	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KAM345_000970	COG0583	DNA-binding transcription factor activity
KAM345_001010	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KAM345_001020	COG2166	iron-sulfur cluster assembly
KAM345_001030	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KAM345_001070	COG1063	alcohol dehydrogenase
KAM345_001100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KAM345_001110	COG0438	transferase activity, transferring glycosyl groups
KAM345_001140	COG0110	maltose O-acetyltransferase activity
KAM345_001160	COG0604	alcohol dehydrogenase
KAM345_001200	COG1580	Controls the rotational direction of flagella during chemotaxis
KAM345_001210	COG3161	chorismate lyase activity
KAM345_001220	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KAM345_001230	COG2937	Belongs to the GPAT DAPAT family
KAM345_001240	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KAM345_001270	COG0534	Mate efflux family protein
KAM345_001280	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KAM345_001290	COG2205	protein histidine kinase activity
KAM345_001300	COG0745	RESPONSE REGULATOR receiver
KAM345_001320	COG1045	serine acetyltransferase
KAM345_001340	COG3074	FtsZ-dependent cytokinesis
KAM345_001350	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
KAM345_001360	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KAM345_001360	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KAM345_001370	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KAM345_001380	COG1609	Transcriptional regulator
KAM345_001390	COG3250	beta-galactosidase activity
KAM345_001400	COG2731	YhcH YjgK YiaL family protein
KAM345_001410	COG0531	amino acid
KAM345_001420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM345_001430	COG0531	amino acid
KAM345_001440	COG0385	Bile acid
KAM345_001450	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KAM345_001500	COG0583	DNA-binding transcription factor activity
KAM345_001510	COG1079	Belongs to the binding-protein-dependent transport system permease family
KAM345_001520	COG4603	Belongs to the binding-protein-dependent transport system permease family
KAM345_001530	COG3845	ABC transporter
KAM345_001540	COG1744	ABC transporter substrate-binding protein PnrA-like
KAM345_001570	COG0210	DNA helicase
KAM345_001590	COG3385	transposase activity
KAM345_001610	COG1943	Transposase
KAM345_001620	COG0583	DNA-binding transcription factor activity
KAM345_001710	COG1280	lysine exporter protein (LysE YggA)
KAM345_001730	COG2962	Rard protein
KAM345_001750	COG1012	belongs to the aldehyde dehydrogenase family
KAM345_001760	COG1396	sequence-specific DNA binding
KAM345_001770	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KAM345_001790	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KAM345_001790	COG0519	Catalyzes the synthesis of GMP from XMP
KAM345_001810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM345_001850	COG1322	Protein conserved in bacteria
KAM345_001860	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KAM345_001870	COG0569	domain protein
KAM345_001880	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KAM345_001880	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KAM345_001890	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KAM345_001900	COG0242	peptide deformylase activity
KAM345_001920	COG0758	DNA mediated transformation
KAM345_001930	COG2922	Belongs to the Smg family
KAM345_001940	COG0551	DNA topoisomerase type I activity
KAM345_001950	COG0009	L-threonylcarbamoyladenylate synthase
KAM345_001960	COG0408	coproporphyrinogen oxidase activity
KAM345_001970	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KAM345_001980	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KAM345_002000	COG3078	GTPase activator activity
KAM345_002030	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KAM345_002050	COG3852	Histidine kinase
KAM345_002070	COG0174	glutamine synthetase
KAM345_002080	COG1217	gtp-binding protein TYPA
KAM345_002090	COG1295	ribonuclease BN
KAM345_002100	COG1490	D-aminoacyl-tRNA deacylase activity
KAM345_002120	COG0456	acetyltransferase
KAM345_002140	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KAM345_002150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KAM345_002160	COG2610	gluconate transmembrane transporter activity
KAM345_002170	COG3265	gluconokinase activity
KAM345_002180	COG0129	dihydroxy-acid dehydratase activity
KAM345_002190	COG0800	Aldolase
KAM345_002220	COG1609	Transcriptional regulator
KAM345_002240	COG4942	peptidase
KAM345_002250	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KAM345_002260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KAM345_002270	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KAM345_002280	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KAM345_002290	COG0316	Belongs to the HesB IscA family
KAM345_002290	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KAM345_002300	COG1040	competence protein
KAM345_002310	COG0596	Alpha beta hydrolase
KAM345_002340	COG2183	response to ionizing radiation
KAM345_002350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KAM345_002370	COG2205	protein histidine kinase activity
KAM345_002390	COG0051	transcription antitermination factor activity, RNA binding
KAM345_002400	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KAM345_002410	COG0088	Forms part of the polypeptide exit tunnel
KAM345_002420	COG0089	rRNA binding
KAM345_002430	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KAM345_002440	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KAM345_002450	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KAM345_002460	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KAM345_002470	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KAM345_002480	COG0255	Belongs to the universal ribosomal protein uL29 family
KAM345_002490	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KAM345_002500	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KAM345_002510	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KAM345_002520	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KAM345_002530	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KAM345_002540	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KAM345_002550	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KAM345_002560	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KAM345_002570	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KAM345_002580	COG1841	ribosomal large subunit assembly
KAM345_002590	COG0200	Binds to the 23S rRNA
KAM345_002600	COG0201	protein transport
KAM345_002610	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KAM345_002620	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KAM345_002630	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KAM345_002640	COG0202	RNA polymerase activity
KAM345_002650	COG0203	ribosomal protein L17
KAM345_002710	COG2249	NAD(P)H dehydrogenase (quinone) activity
KAM345_002720	COG0583	DNA-binding transcription factor activity
KAM345_002730	COG4221	oxidoreductase activity
KAM345_002760	COG1770	oligopeptidase
KAM345_002770	COG2358	TRAP transporter, solute receptor (TAXI family
KAM345_002800	COG3714	YhhN family
KAM345_002830	COG0583	DNA-binding transcription factor activity
KAM345_002850	COG1301	dicarboxylic acid transport
KAM345_002870	COG2095	MarC family integral membrane protein
KAM345_002890	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KAM345_002910	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KAM345_002930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KAM345_002980	COG0742	ribosomal rna small subunit methyltransferase
KAM345_002990	COG0552	protein localization to endoplasmic reticulum
KAM345_003000	COG2884	Cell division ATP-binding protein ftsE
KAM345_003010	COG2177	Part of the ABC transporter FtsEX involved in
KAM345_003030	COG0288	reversible hydration of carbon dioxide
KAM345_003040	COG2188	Transcriptional regulator
KAM345_003050	COG1228	amidohydrolase
KAM345_003060	COG0010	Belongs to the arginase family
KAM345_003070	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KAM345_003080	COG2986	histidine ammonia-lyase
KAM345_003090	COG0387	Pfam Sodium calcium exchanger
KAM345_003100	COG2200	EAL domain
KAM345_003210	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KAM345_003220	COG1459	type II secretion system
KAM345_003250	COG2165	general secretion pathway protein
KAM345_003260	COG4969	Belongs to the N-Me-Phe pilin family
KAM345_003320	COG1077	Cell shape determining protein MreB Mrl
KAM345_003330	COG1792	Involved in formation and maintenance of cell shape
KAM345_003340	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KAM345_003350	COG0424	maF-like protein
KAM345_003360	COG1530	ribonuclease E activity
KAM345_003370	COG3164	Protein of unknown function
KAM345_003380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KAM345_003390	COG0312	modulator of DNA gyrase
KAM345_003430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM345_003430	COG1263	PTS System
KAM345_003440	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KAM345_003470	COG0477	Major facilitator Superfamily
KAM345_003490	COG2321	neutral zinc metallopeptidase
KAM345_003560	COG0189	ligase activity
KAM345_003570	COG0642	Histidine kinase
KAM345_003580	COG0745	RESPONSE REGULATOR receiver
KAM345_003610	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KAM345_003630	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KAM345_003650	COG2022	thiamine diphosphate biosynthetic process
KAM345_003660	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KAM345_003690	COG0110	maltose O-acetyltransferase activity
KAM345_003720	COG3932	Exopolysaccharide synthesis, ExoD
KAM345_003770	COG1733	regulation of RNA biosynthetic process
KAM345_003830	COG1494	fructose-1,6-bisphosphatase
KAM345_003850	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KAM345_003860	COG5007	Belongs to the BolA IbaG family
KAM345_003880	COG2854	intermembrane phospholipid transfer
KAM345_003890	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KAM345_003900	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KAM345_003910	COG1127	ABC transporter
KAM345_003920	COG0517	IMP dehydrogenase activity
KAM345_003920	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KAM345_003930	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KAM345_003950	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KAM345_003960	COG1137	ATPase activity
KAM345_003970	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KAM345_003990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM345_004000	COG1660	Displays ATPase and GTPase activities
KAM345_004010	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM345_004050	COG3964	amidohydrolase
KAM345_004110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KAM345_004120	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KAM345_004140	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KAM345_004150	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KAM345_004160	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KAM345_004170	COG0723	plastoquinol--plastocyanin reductase activity
KAM345_004180	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KAM345_004190	COG2857	Cytochrome c1
KAM345_004200	COG0625	glutathione transferase activity
KAM345_004210	COG2969	positive regulation of protein catabolic process
KAM345_004220	COG2823	Periplasmic or secreted lipoprotein
KAM345_004230	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KAM345_004240	COG0792	nuclease activity
KAM345_004250	COG3107	peptidoglycan biosynthetic process
KAM345_004260	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KAM345_004270	COG2001	Belongs to the MraZ family
KAM345_004280	COG0275	rRNA processing
KAM345_004290	COG3116	cell division
KAM345_004300	COG0768	penicillin binding
KAM345_004310	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KAM345_004320	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KAM345_004330	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KAM345_004340	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KAM345_004350	COG0772	Belongs to the SEDS family
KAM345_004360	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KAM345_004370	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KAM345_004380	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KAM345_004390	COG0849	cell division
KAM345_004400	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KAM345_004410	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KAM345_004430	COG0653	protein targeting
KAM345_004450	COG0494	nUDIX hydrolase
KAM345_004460	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KAM345_004470	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
KAM345_004490	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KAM345_004500	COG1459	type II secretion system
KAM345_004510	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KAM345_004560	COG2186	Transcriptional regulator
KAM345_004570	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KAM345_004580	COG0508	dehydrogenase complex catalyzes the overall conversion of
KAM345_004590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KAM345_004610	COG0840	transmembrane signaling receptor activity
KAM345_004620	COG0840	transmembrane signaling receptor activity
KAM345_004630	COG1752	Esterase of the alpha-beta hydrolase superfamily
KAM345_004640	COG1049	propionate catabolic process, 2-methylcitrate cycle
KAM345_004650	COG2200	EAL domain
KAM345_004670	COG1280	lysine exporter protein (LysE YggA)
KAM345_004690	COG0523	cobalamin synthesis protein
KAM345_004700	COG0477	Major facilitator Superfamily
KAM345_004730	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KAM345_004740	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KAM345_004790	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KAM345_004810	COG1546	Belongs to the CinA family
KAM345_004820	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KAM345_004830	COG2137	regulation of response to DNA damage stimulus
KAM345_004840	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KAM345_004850	COG0527	aspartate kinase activity
KAM345_004860	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KAM345_004870	COG1686	Belongs to the peptidase S11 family
KAM345_004880	COG0586	Pfam SNARE associated Golgi protein
KAM345_004890	COG1253	flavin adenine dinucleotide binding
KAM345_004900	COG0525	valine-tRNA ligase activity
KAM345_004920	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KAM345_004930	COG0795	lipopolysaccharide-transporting ATPase activity
KAM345_004940	COG0795	lipopolysaccharide-transporting ATPase activity
KAM345_004960	COG0582	viral genome integration into host DNA
KAM345_005060	COG3328	transposase activity
KAM345_005090	COG0004	ammonium transporteR
KAM345_005100	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KAM345_005130	COG2165	general secretion pathway protein
KAM345_005140	COG0084	hydrolase, TatD family'
KAM345_005150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KAM345_005170	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KAM345_005180	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KAM345_005190	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KAM345_005200	COG0813	purine-nucleoside phosphorylase activity
KAM345_005210	COG5002	protein histidine kinase activity
KAM345_005210	COG3447	MASE1 domain protein
KAM345_005210	COG5001	Diguanylate cyclase
KAM345_005230	COG0560	Phosphoserine phosphatase
KAM345_005260	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KAM345_005280	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
KAM345_005290	COG0776	regulation of translation
KAM345_005320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KAM345_005330	COG0735	belongs to the Fur family
KAM345_005370	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KAM345_005380	COG0513	Belongs to the DEAD box helicase family
KAM345_005390	COG3022	response to hydroperoxide
KAM345_005420	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KAM345_005430	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KAM345_005440	COG0762	integral membrane protein
KAM345_005450	COG1872	DUF167
KAM345_005490	COG3112	Uncharacterised protein family (UPF0231)
KAM345_005500	COG3835	regulator
KAM345_005510	COG2610	gluconate transmembrane transporter activity
KAM345_005520	COG1929	Belongs to the glycerate kinase type-1 family
KAM345_005550	COG0583	DNA-binding transcription factor activity
KAM345_005560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KAM345_005590	COG0347	Belongs to the P(II) protein family
KAM345_005620	COG3842	ATPase activity
KAM345_005630	COG2837	iron assimilation
KAM345_005640	COG1438	arginine binding
KAM345_005650	COG1126	abc transporter atp-binding protein
KAM345_005660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM345_005670	COG4215	(ABC) transporter
KAM345_005680	COG4160	amino acid transport
KAM345_005690	COG0039	L-malate dehydrogenase activity
KAM345_005710	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
KAM345_005720	COG1017	nitric oxide dioxygenase activity
KAM345_005720	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KAM345_005740	COG4536	flavin adenine dinucleotide binding
KAM345_005750	COG4137	Cytochrome C assembly protein
KAM345_005760	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KAM345_005770	COG0228	four-way junction DNA binding
KAM345_005780	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KAM345_005790	COG0336	Belongs to the RNA methyltransferase TrmD family
KAM345_005800	COG0335	large ribosomal subunit rRNA binding
KAM345_005820	COG3066	DNA modification
KAM345_005830	COG1051	belongs to the nudix hydrolase family
KAM345_005850	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KAM345_005860	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KAM345_005870	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KAM345_005890	COG0583	DNA-binding transcription factor activity
KAM345_005900	COG0640	Transcriptional regulator
KAM345_005910	COG0268	Binds directly to 16S ribosomal RNA
KAM345_005920	COG0728	peptidoglycan biosynthetic process
KAM345_005930	COG0196	riboflavin kinase activity
KAM345_005940	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KAM345_005950	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KAM345_005960	COG1047	Peptidyl-prolyl cis-trans
KAM345_005970	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KAM345_006030	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KAM345_006030	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KAM345_006060	COG1854	S-ribosylhomocysteine lyase activity
KAM345_006070	COG3706	GGDEF domain
KAM345_006080	COG0557	exoribonuclease II activity
KAM345_006120	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KAM345_006140	COG2153	protein acetylation
KAM345_006160	COG1914	H( )-stimulated, divalent metal cation uptake system
KAM345_006170	COG0360	Binds together with S18 to 16S ribosomal RNA
KAM345_006180	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KAM345_006190	COG0359	binds to the 23S rRNA
KAM345_006270	COG1238	metal cluster binding
KAM345_006280	COG0612	Peptidase, M16
KAM345_006290	COG2918	glutathione biosynthetic process
KAM345_006300	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KAM345_006310	COG1027	Aspartate ammonia-lyase
KAM345_006320	COG3030	protein affecting phage T7 exclusion by the F plasmid
KAM345_006330	COG0534	Mate efflux family protein
KAM345_006350	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KAM345_006360	COG0459	protein refolding
KAM345_006400	COG0564	pseudouridine synthase activity
KAM345_006410	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KAM345_006420	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KAM345_006440	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KAM345_006450	COG4208	sulfate ABC transporter
KAM345_006460	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KAM345_006470	COG0583	DNA-binding transcription factor activity
KAM345_006480	COG3397	chitin binding
KAM345_006490	COG0840	transmembrane signaling receptor activity
KAM345_006540	COG1328	CTP reductase activity
KAM345_006550	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KAM345_006580	COG1448	Aminotransferase
KAM345_006590	COG2194	sulfuric ester hydrolase activity
KAM345_006630	COG1215	transferase activity, transferring glycosyl groups
KAM345_006640	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KAM345_006650	COG0457	Tetratricopeptide repeat
KAM345_006650	COG3118	belongs to the thioredoxin family
KAM345_006720	COG0513	Belongs to the DEAD box helicase family
KAM345_006730	COG0840	transmembrane signaling receptor activity
KAM345_006750	COG4166	transmembrane transport
KAM345_006780	COG1024	Enoyl-CoA hydratase
KAM345_006810	COG4221	oxidoreductase activity
KAM345_006820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KAM345_006830	COG0442	prolyl-tRNA aminoacylation
KAM345_006840	COG0840	transmembrane signaling receptor activity
KAM345_006860	COG0632	four-way junction helicase activity
KAM345_006870	COG2255	four-way junction helicase activity
KAM345_006880	COG1271	oxidase subunit
KAM345_006890	COG1294	oxidase, subunit
KAM345_006900	COG3790	cyd operon protein YbgE
KAM345_006910	COG0824	Thioesterase
KAM345_006920	COG0811	peptide transport
KAM345_006950	COG0823	Involved in the tonB-independent uptake of proteins
KAM345_006960	COG2885	chlorophyll binding
KAM345_006970	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
KAM345_006980	COG0840	transmembrane signaling receptor activity
KAM345_006990	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KAM345_007010	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KAM345_007020	COG1640	4-alpha-glucanotransferase
KAM345_007030	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KAM345_007090	COG2130	NADP-dependent
KAM345_007100	COG1846	Transcriptional regulator
KAM345_007160	COG0561	phosphatase activity
KAM345_007190	COG0733	neurotransmitter:sodium symporter activity
KAM345_007200	COG0733	neurotransmitter:sodium symporter activity
KAM345_007230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KAM345_007270	COG1022	Amp-dependent synthetase and ligase
KAM345_007290	COG0456	acetyltransferase
KAM345_007320	COG2425	protein containing a von Willebrand factor type A (vWA) domain
KAM345_007330	COG5002	protein histidine kinase activity
KAM345_007330	COG5001	Diguanylate cyclase
KAM345_007390	COG1902	pentaerythritol trinitrate reductase activity
KAM345_007420	COG2957	Belongs to the agmatine deiminase family
KAM345_007430	COG0154	amidase activity
KAM345_007440	COG3039	Transposase
KAM345_007480	COG2207	Transcriptional regulator
KAM345_007480	COG1917	Cupin 2, conserved barrel domain protein
KAM345_007500	COG0513	Belongs to the DEAD box helicase family
KAM345_007510	COG2199	diguanylate cyclase activity
KAM345_007510	COG2203	Gaf domain
KAM345_007580	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
KAM345_007600	COG0577	efflux transmembrane transporter activity
KAM345_007600	COG1136	(ABC) transporter
KAM345_007610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM345_007620	COG0745	RESPONSE REGULATOR receiver
KAM345_007630	COG2205	protein histidine kinase activity
KAM345_007690	COG1280	lysine exporter protein (LysE YggA)
KAM345_007700	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KAM345_007710	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KAM345_007730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM345_007790	COG0745	RESPONSE REGULATOR receiver
KAM345_007800	COG3104	oligopeptide transport
KAM345_007810	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KAM345_007820	COG1555	photosystem II stabilization
KAM345_007840	COG2350	Protein conserved in bacteria
KAM345_007850	COG2917	probably involved in intracellular septation
KAM345_007860	COG0076	glutamate decarboxylase activity
KAM345_007870	COG1272	protein, Hemolysin III
KAM345_007880	COG2985	domain, Protein
KAM345_007880	COG0569	domain protein
KAM345_007900	COG0477	Major facilitator Superfamily
KAM345_007910	COG0583	DNA-binding transcription factor activity
KAM345_007920	COG3227	Zinc metalloprotease (Elastase)
KAM345_007930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KAM345_007940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KAM345_007960	COG2731	YhcH YjgK YiaL family protein
KAM345_007980	COG0668	transmembrane transport
KAM345_008000	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KAM345_008020	COG0789	Transcriptional regulator
KAM345_008030	COG2801	Transposase and inactivated derivatives
KAM345_008120	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KAM345_008140	COG0488	(ABC) transporter
KAM345_008150	COG0516	GMP reductase activity
KAM345_008150	COG0517	IMP dehydrogenase activity
KAM345_008170	COG0784	Response regulator, receiver
KAM345_008170	COG0835	chemotaxis
KAM345_008180	COG2755	lipolytic protein G-D-S-L family
KAM345_008190	COG4181	ATPase activity
KAM345_008200	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KAM345_008210	COG1090	epimerase
KAM345_008220	COG2200	EAL domain
KAM345_008230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KAM345_008240	COG2234	aminopeptidase activity
KAM345_008240	COG4935	Belongs to the peptidase S8 family
KAM345_008250	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KAM345_008260	COG3171	Protein conserved in bacteria
KAM345_008270	COG2066	Belongs to the glutaminase family
KAM345_008280	COG2897	thiosulfate sulfurtransferase activity
KAM345_008300	COG1132	(ABC) transporter
KAM345_008330	COG0582	viral genome integration into host DNA
KAM345_008380	COG3039	Transposase
KAM345_008410	COG4974	Belongs to the 'phage' integrase family
KAM345_008480	COG3039	Transposase
KAM345_008500	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
KAM345_008510	COG3300	MHYT domain
KAM345_008510	COG5001	Diguanylate cyclase
KAM345_008550	COG4628	conserved protein (DUF2132)
KAM345_008560	COG0688	phosphatidylethanolamine metabolic process
KAM345_008570	COG1162	GTPase activity
KAM345_008580	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KAM345_008590	COG1278	Cold shock
KAM345_008610	COG0840	transmembrane signaling receptor activity
KAM345_008620	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KAM345_008670	COG0848	biopolymer transport protein
KAM345_008680	COG0811	peptide transport
KAM345_008690	COG0811	peptide transport
KAM345_008710	COG4206	TonB-dependent receptor
KAM345_008720	COG4174	ABC transporter (Permease)
KAM345_008730	COG4239	(ABC) transporter, permease
KAM345_008750	COG0444	Belongs to the ABC transporter superfamily
KAM345_008760	COG4608	Belongs to the ABC transporter superfamily
KAM345_008780	COG2195	Cleaves the N-terminal amino acid of tripeptides
KAM345_008790	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
KAM345_008800	COG1073	alpha beta
KAM345_008830	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KAM345_008880	COG0243	molybdopterin cofactor binding
KAM345_008890	COG1648	precorrin-2 dehydrogenase activity
KAM345_008890	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KAM345_008910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KAM345_008910	COG1116	anion transmembrane transporter activity
KAM345_008920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KAM345_008930	COG1116	anion transmembrane transporter activity
KAM345_008940	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KAM345_008940	COG2146	nitrite reductase [NAD(P)H] activity
KAM345_008950	COG2146	nitrite reductase [NAD(P)H] activity
KAM345_008950	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KAM345_008960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM345_008970	COG2313	pseudouridylate synthase activity
KAM345_009010	COG0521	Mo-molybdopterin cofactor biosynthetic process
KAM345_009030	COG2966	Psort location CytoplasmicMembrane, score
KAM345_009040	COG3610	response to peptide
KAM345_009060	COG4175	Glycine betaine
KAM345_009070	COG4176	ABC-type proline glycine betaine transport system permease component
KAM345_009080	COG2113	Glycine betaine
KAM345_009090	COG0175	sulfate reduction
KAM345_009100	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KAM345_009110	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KAM345_009120	COG0384	phenazine biosynthesis protein PhzF
KAM345_009130	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KAM345_009140	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KAM345_009160	COG0786	glutamate:sodium symporter activity
KAM345_009170	COG0252	asparaginase activity
KAM345_009180	COG3139	Protein of unknown function (DUF1315)
KAM345_009220	COG0616	signal peptide processing
KAM345_009230	COG1902	pentaerythritol trinitrate reductase activity
KAM345_009230	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAM345_009240	COG0778	Nitroreductase
KAM345_009260	COG0110	maltose O-acetyltransferase activity
KAM345_009280	COG2264	protein methyltransferase activity
KAM345_009290	COG0604	alcohol dehydrogenase
KAM345_009300	COG0583	DNA-binding transcription factor activity
KAM345_009310	COG1263	PTS System
KAM345_009310	COG2190	(PTS) system
KAM345_009310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM345_009320	COG4145	pantothenate transmembrane transporter activity
KAM345_009330	COG3924	membrane
KAM345_009340	COG0439	Biotin carboxylase
KAM345_009350	COG0511	ligase activity, forming carbon-carbon bonds
KAM345_009360	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KAM345_009370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KAM345_009400	COG3381	protein complex oligomerization
KAM345_009420	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KAM345_009440	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KAM345_009450	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KAM345_009450	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KAM345_009480	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KAM345_009490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KAM345_009500	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KAM345_009510	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KAM345_009520	COG4172	Belongs to the ABC transporter superfamily
KAM345_009540	COG0601	transmembrane transport
KAM345_009550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAM345_009560	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KAM345_009570	COG0142	geranyltranstransferase activity
KAM345_009580	COG1722	exodeoxyribonuclease VII activity
KAM345_009590	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KAM345_009600	COG1360	Flagellar Motor Protein
KAM345_009630	COG1534	Rna-binding protein
KAM345_009640	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KAM345_009660	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KAM345_009670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KAM345_009690	COG0149	triose-phosphate isomerase activity
KAM345_009700	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KAM345_009710	COG0779	Required for maturation of 30S ribosomal subunits
KAM345_009720	COG0195	Participates in both transcription termination and antitermination
KAM345_009730	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KAM345_009740	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KAM345_009750	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KAM345_009760	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KAM345_009770	COG1185	polyribonucleotide nucleotidyltransferase activity
KAM345_009780	COG2211	Major facilitator Superfamily
KAM345_009790	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KAM345_009800	COG1422	Protein of unknown function (DUF1090)
KAM345_009810	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KAM345_009820	COG0826	peptidase U32
KAM345_009830	COG3039	Transposase
KAM345_009850	COG4251	negative regulation of phosphorylation
KAM345_009890	COG3039	Transposase
KAM345_009900	COG2801	Transposase and inactivated derivatives
KAM345_009960	COG0312	modulator of DNA gyrase
KAM345_009970	COG0312	modulator of DNA gyrase
KAM345_009990	COG4974	Belongs to the 'phage' integrase family
KAM345_010000	COG1970	mechanosensitive ion channel activity
KAM345_010030	COG0789	Transcriptional regulator
KAM345_010060	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM345_010080	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KAM345_010090	COG0321	lipoyl(octanoyl) transferase activity
KAM345_010100	COG2921	Belongs to the UPF0250 family
KAM345_010110	COG1686	Belongs to the peptidase S11 family
KAM345_010130	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KAM345_010140	COG2951	lytic endotransglycosylase activity
KAM345_010150	COG0772	Belongs to the SEDS family
KAM345_010160	COG0768	penicillin binding
KAM345_010170	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KAM345_010180	COG0799	negative regulation of ribosome biogenesis
KAM345_010190	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KAM345_010230	COG0495	leucyl-tRNA aminoacylation
KAM345_010240	COG2888	peptidyl-tyrosine sulfation
KAM345_010250	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KAM345_010260	COG4535	Mg2 and Co2 transporter CorC
KAM345_010270	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KAM345_010280	COG1702	phosphate starvation-inducible protein PhoH
KAM345_010290	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KAM345_010300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KAM345_010310	COG1335	isochorismatase
KAM345_010320	COG1278	Cold shock
KAM345_010350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAM345_010380	COG2199	diguanylate cyclase activity
KAM345_010400	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KAM345_010430	COG1464	Belongs to the NlpA lipoprotein family
KAM345_010440	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KAM345_010450	COG2011	ABC-type metal ion transport system permease component
KAM345_010460	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KAM345_010480	COG0516	GMP reductase activity
KAM345_010500	COG0642	Histidine kinase
KAM345_010530	COG0300	oxidoreductase activity
KAM345_010580	COG3214	Protein conserved in bacteria
KAM345_010590	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
KAM345_010600	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
KAM345_010610	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KAM345_010620	COG1053	succinate dehydrogenase
KAM345_010640	COG0584	glycerophosphoryl diester phosphodiesterase
KAM345_010650	COG3264	Mechanosensitive ion channel
KAM345_010650	COG1511	domain protein
KAM345_010670	COG0739	heme binding
KAM345_010690	COG0583	DNA-binding transcription factor activity
KAM345_010740	COG0583	DNA-binding transcription factor activity
KAM345_010750	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KAM345_010810	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KAM345_010820	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KAM345_010840	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KAM345_010850	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KAM345_010860	COG0546	phosphoglycolate phosphatase activity
KAM345_010870	COG0180	Tryptophanyl-tRNA synthetase
KAM345_010900	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KAM345_010920	COG1012	belongs to the aldehyde dehydrogenase family
KAM345_010950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAM345_010980	COG0657	acetylesterase activity
KAM345_011000	COG0471	metal ion transport
KAM345_011000	COG0490	domain, Protein
KAM345_011010	COG0012	GTP binding
KAM345_011020	COG0193	aminoacyl-tRNA hydrolase activity
KAM345_011030	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KAM345_011040	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KAM345_011050	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KAM345_011060	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KAM345_011070	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KAM345_011080	COG2890	protein-(glutamine-N5) methyltransferase activity
KAM345_011100	COG2912	Transglutaminase-like superfamily
KAM345_011110	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KAM345_011120	COG1301	dicarboxylic acid transport
KAM345_011140	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KAM345_011170	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KAM345_011180	COG1115	amino acid carrier protein
KAM345_011220	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KAM345_011240	COG0189	ligase activity
KAM345_011250	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KAM345_011270	COG3091	SprT-like family
KAM345_011290	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KAM345_011310	COG0251	oxidation-reduction process
KAM345_011340	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KAM345_011350	COG0739	heme binding
KAM345_011360	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KAM345_011370	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
KAM345_011370	COG3408	Glycogen debranching enzyme
KAM345_011390	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
KAM345_011390	COG3408	Glycogen debranching enzyme
KAM345_011410	COG1881	PFAM PEBP family protein
KAM345_011420	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KAM345_011430	COG0583	DNA-binding transcription factor activity
KAM345_011450	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KAM345_011470	COG0583	DNA-binding transcription factor activity
KAM345_011480	COG1028	Short-chain dehydrogenase reductase Sdr
KAM345_011490	COG0616	signal peptide processing
KAM345_011500	COG3724	N-succinylarginine dihydrolase activity
KAM345_011540	COG0840	transmembrane signaling receptor activity
KAM345_011560	COG2971	BadF BadG BcrA BcrD
KAM345_011580	COG4608	Belongs to the ABC transporter superfamily
KAM345_011590	COG0444	Belongs to the ABC transporter superfamily
KAM345_011620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAM345_011650	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KAM345_011690	COG0640	Transcriptional regulator
KAM345_011700	COG0798	PFAM Bile acid sodium symporter
KAM345_011710	COG1393	Belongs to the ArsC family
KAM345_011740	COG1677	Flagellar hook-basal body complex protein FliE
KAM345_011760	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KAM345_011870	COG1684	flagellar biosynthetic protein fliR
KAM345_011890	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KAM345_011940	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KAM345_011950	COG0643	Histidine kinase
KAM345_011950	COG0784	Response regulator, receiver
KAM345_011950	COG2198	Histidine kinase
KAM345_011970	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KAM345_011980	COG1360	Flagellar Motor Protein
KAM345_011990	COG1192	Involved in chromosome partitioning
KAM345_012010	COG0835	chemotaxis
KAM345_012040	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KAM345_012050	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KAM345_012060	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KAM345_012070	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KAM345_012080	COG1138	Cytochrome C-type biogenesis protein
KAM345_012090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KAM345_012110	COG0457	Tetratricopeptide repeat
KAM345_012140	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KAM345_012150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KAM345_012150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KAM345_012180	COG0259	pyridoxamine-phosphate oxidase activity
KAM345_012240	COG3153	acetyltransferase
KAM345_012270	COG0800	Aldolase
KAM345_012280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM345_012300	COG2721	sulfolactate sulfo-lyase activity
KAM345_012310	COG0246	Mannitol dehydrogenase
KAM345_012380	COG5433	transposase activity
KAM345_012390	COG3039	Transposase
KAM345_012450	COG2916	Histone family protein nucleoid-structuring protein H-NS
KAM345_012490	COG3385	transposase activity
KAM345_012500	COG2850	peptidyl-arginine hydroxylation
KAM345_012520	COG5433	transposase activity
KAM345_012550	COG0210	DNA helicase
KAM345_012620	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KAM345_012630	COG2867	negative regulation of translational initiation
KAM345_012640	COG2914	Belongs to the UPF0125 (RnfH) family
KAM345_012650	COG0702	epimerase
KAM345_012660	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAM345_012670	COG1454	alcohol dehydrogenase
KAM345_012680	COG1454	alcohol dehydrogenase
KAM345_012700	COG0564	pseudouridine synthase activity
KAM345_012710	COG1957	nucleoside hydrolase
KAM345_012770	COG1280	lysine exporter protein (LysE YggA)
KAM345_012790	COG3263	regulation of cellular component size
KAM345_012810	COG1876	peptidase activity
KAM345_012820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KAM345_012830	COG1393	Belongs to the ArsC family
KAM345_012840	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM345_012880	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM345_012930	COG3069	C4-dicarboxylate transmembrane transporter activity
KAM345_012960	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KAM345_012970	COG0017	Asparaginyl-tRNA synthetase
KAM345_013020	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KAM345_013030	COG0156	8-amino-7-oxononanoate synthase activity
KAM345_013040	COG1073	alpha beta
KAM345_013040	COG2226	methyltransferase
KAM345_013050	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KAM345_013060	COG0501	Belongs to the peptidase M48B family
KAM345_013070	COG0633	Ferredoxin
KAM345_013070	COG0633	Ferredoxin
KAM345_013070	COG3217	Mosc domain protein beta barrel domain protein
KAM345_013070	COG3217	Mosc domain protein beta barrel domain protein
KAM345_013090	COG0674	pyruvate-flavodoxin oxidoreductase activity
KAM345_013090	COG1013	pyruvate-flavodoxin oxidoreductase activity
KAM345_013090	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KAM345_013090	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KAM345_013100	COG2841	Protein conserved in bacteria
KAM345_013120	COG0534	Mate efflux family protein
KAM345_013170	COG1454	alcohol dehydrogenase
KAM345_013190	COG1309	transcriptional regulator
KAM345_013220	COG0791	NLP P60 protein
KAM345_013230	COG0583	DNA-binding transcription factor activity
KAM345_013270	COG0500	methyltransferase
KAM345_013280	COG4106	trans-aconitate 2-methyltransferase activity
KAM345_013290	COG1801	Protein of unknown function DUF72
KAM345_013300	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KAM345_013310	COG0217	transcriptional regulatory protein
KAM345_013320	COG2194	sulfuric ester hydrolase activity
KAM345_013330	COG1846	Transcriptional regulator
KAM345_013330	COG1940	carbohydrate kinase activity
KAM345_013340	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KAM345_013350	COG0363	glucosamine-6-phosphate deaminase activity
KAM345_013360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM345_013360	COG1263	PTS System
KAM345_013360	COG2190	(PTS) system
KAM345_013390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KAM345_013400	COG0735	belongs to the Fur family
KAM345_013420	COG0716	FMN binding
KAM345_013450	COG0596	Alpha beta hydrolase
KAM345_013470	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
KAM345_013480	COG0033	Phosphoglucomutase
KAM345_013500	COG1846	Transcriptional regulator
KAM345_013510	COG2951	lytic endotransglycosylase activity
KAM345_013520	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KAM345_013530	COG4136	ATPase activity
KAM345_013550	COG4134	Bacterial extracellular solute-binding protein
KAM345_013560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KAM345_013570	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KAM345_013590	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KAM345_013610	COG0729	surface antigen
KAM345_013620	COG2911	Protein conserved in bacteria
KAM345_013640	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KAM345_013660	COG0741	lytic transglycosylase activity
KAM345_013690	COG1607	acyl-coa hydrolase
KAM345_013720	COG0741	lytic transglycosylase activity
KAM345_013720	COG1388	LysM domain
KAM345_013730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KAM345_013740	COG2226	methyltransferase
KAM345_013750	COG0328	RNA-DNA hybrid ribonuclease activity
KAM345_013760	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KAM345_013780	COG3437	response regulator, receiver
KAM345_013780	COG0784	Response regulator, receiver
KAM345_013790	COG1960	acyl-CoA dehydrogenase activity
KAM345_013800	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KAM345_013810	COG0121	glutamine amidotransferase
KAM345_013830	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KAM345_013880	COG2197	response regulator
KAM345_013890	COG3850	Histidine kinase
KAM345_013900	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KAM345_013910	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KAM345_013910	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
KAM345_013930	COG0243	molybdopterin cofactor binding
KAM345_013940	COG0437	4 iron, 4 sulfur cluster binding
KAM345_013950	COG0348	domain, Protein
KAM345_013970	COG3005	denitrification pathway
KAM345_013980	COG0521	Mo-molybdopterin cofactor biosynthetic process
KAM345_013990	COG0315	cyclic pyranopterin monophosphate synthase activity
KAM345_014000	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KAM345_014010	COG0314	molybdopterin synthase activity
KAM345_014040	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KAM345_014050	COG2267	carboxylic ester hydrolase activity
KAM345_014080	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KAM345_014100	COG0302	gtp cyclohydrolase
KAM345_014110	COG0840	transmembrane signaling receptor activity
KAM345_014120	COG0840	transmembrane signaling receptor activity
KAM345_014130	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KAM345_014150	COG0583	DNA-binding transcription factor activity
KAM345_014180	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KAM345_014210	COG2195	Cleaves the N-terminal amino acid of tripeptides
KAM345_014220	COG1166	arginine decarboxylase activity
KAM345_014270	COG1061	Type III restriction enzyme res subunit
KAM345_014300	COG0675	Transposase, IS605 OrfB family
KAM345_014320	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KAM345_014330	COG1187	pseudouridine synthase activity
KAM345_014350	COG2807	transmembrane transport
KAM345_014370	COG0583	DNA-binding transcription factor activity
KAM345_014400	COG1607	acyl-coa hydrolase
KAM345_014410	COG2979	Protein of unknown function (DUF533)
KAM345_014430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KAM345_014450	COG1294	oxidase, subunit
KAM345_014460	COG2814	Major facilitator Superfamily
KAM345_014470	COG0656	L-ascorbic acid biosynthetic process
KAM345_014510	COG0583	DNA-binding transcription factor activity
KAM345_014520	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KAM345_014530	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KAM345_014540	COG2271	Major facilitator Superfamily
KAM345_014550	COG1349	DNA-binding transcription factor activity
KAM345_014580	COG0584	glycerophosphoryl diester phosphodiesterase
KAM345_014590	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAM345_014600	COG0287	Prephenate dehydrogenase
KAM345_014600	COG1605	Chorismate mutase
KAM345_014620	COG3085	chromosome segregation
KAM345_014630	COG4574	serine-type endopeptidase inhibitor activity
KAM345_014660	COG0675	Transposase, IS605 OrfB family
KAM345_014680	COG4771	TonB-dependent receptor
KAM345_014690	COG3083	sulfuric ester hydrolase activity
KAM345_014700	COG3082	Protein of unknown function (DUF1414)
KAM345_014710	COG3081	Nucleoid-associated protein
KAM345_014730	COG1175	transmembrane transport
KAM345_014740	COG3833	ABC-type maltose transport systems, permease component
KAM345_014750	COG3842	ATPase activity
KAM345_014770	COG0596	Alpha beta hydrolase
KAM345_014800	COG0425	Belongs to the sulfur carrier protein TusA family
KAM345_014810	COG4783	chaperone-mediated protein folding
KAM345_014830	COG1393	Belongs to the ArsC family
KAM345_014870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM345_014880	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KAM345_014890	COG2431	L-lysine efflux transmembrane transporter activity
KAM345_014910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM345_014930	COG4160	amino acid transport
KAM345_014950	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KAM345_014970	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAM345_014980	COG2373	Large extracellular alpha-helical protein
KAM345_014990	COG4953	penicillin-binding protein 1C
KAM345_015010	COG0582	viral genome integration into host DNA
KAM345_015090	COG2974	May be involved in recombination
KAM345_015170	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KAM345_015260	COG3617	BRO family, N-terminal domain
KAM345_015380	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KAM345_015830	COG3328	transposase activity
KAM345_015840	COG1484	DNA-dependent DNA replication
KAM345_015850	COG4584	PFAM Integrase catalytic
KAM345_015860	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM345_015940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KAM345_015940	COG0301	tRNA thio-modification
KAM345_015970	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KAM345_015980	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KAM345_015990	COG1334	flagellar protein FlaG
KAM345_016050	COG2089	acid synthase
KAM345_016080	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KAM345_016090	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
KAM345_016110	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KAM345_016120	COG1086	Polysaccharide biosynthesis protein
KAM345_016130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KAM345_016150	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KAM345_016190	COG0346	lactoylglutathione lyase activity
KAM345_016200	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KAM345_016210	COG4660	Part of a membrane complex involved in electron transport
KAM345_016220	COG4659	FMN binding
KAM345_016230	COG4658	electron transport chain
KAM345_016240	COG4656	Part of a membrane complex involved in electron transport
KAM345_016250	COG4656	Part of a membrane complex involved in electron transport
KAM345_016260	COG2878	Part of a membrane complex involved in electron transport
KAM345_016270	COG4657	Part of a membrane complex involved in electron transport
KAM345_016280	COG0675	Transposase, IS605 OrfB family
KAM345_016290	COG0697	spore germination
KAM345_016320	COG3039	Transposase
KAM345_016360	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KAM345_016380	COG1288	antiporter activity
KAM345_016390	COG0436	Aminotransferase
KAM345_016410	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KAM345_016420	COG2027	D-alanyl-D-alanine carboxypeptidase
KAM345_016430	COG1061	Type III restriction enzyme res subunit
KAM345_016440	COG1566	PFAM secretion protein HlyD family protein
KAM345_016470	COG0675	Transposase, IS605 OrfB family
KAM345_016480	COG3264	Mechanosensitive ion channel
KAM345_016480	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KAM345_016490	COG1966	Carbon starvation protein
KAM345_016500	COG3279	Response regulator of the LytR AlgR family
KAM345_016510	COG3275	phosphorelay sensor kinase activity
KAM345_016530	COG1012	belongs to the aldehyde dehydrogenase family
KAM345_016530	COG1454	alcohol dehydrogenase
KAM345_016540	COG2095	MarC family integral membrane protein
KAM345_016560	COG0601	transmembrane transport
KAM345_016570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAM345_016580	COG0444	Belongs to the ABC transporter superfamily
KAM345_016600	COG0861	Integral membrane protein TerC family
KAM345_016610	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KAM345_016630	COG1301	dicarboxylic acid transport
KAM345_016660	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KAM345_016690	COG0537	adenosine 5'-monophosphoramidase activity
KAM345_016760	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAM345_016770	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAM345_016800	COG2354	Protein conserved in bacteria
KAM345_016810	COG1164	Oligoendopeptidase f
KAM345_016820	COG1164	Oligoendopeptidase f
KAM345_016830	COG3150	esterase
KAM345_016840	COG1252	NADH dehydrogenase
KAM345_016850	COG0393	Putative heavy-metal-binding
KAM345_016860	COG1368	sulfuric ester hydrolase activity
KAM345_016880	COG0527	aspartate kinase activity
KAM345_016890	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KAM345_016890	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KAM345_016900	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KAM345_016950	COG0583	DNA-binding transcription factor activity
KAM345_016960	COG1620	l-lactate permease
KAM345_016970	COG0247	lactate metabolic process
KAM345_016980	COG1139	Iron-sulfur cluster binding protein
KAM345_017020	COG0577	efflux transmembrane transporter activity
KAM345_017030	COG1136	(ABC) transporter
KAM345_017070	COG2814	Major facilitator Superfamily
KAM345_017120	COG0672	)-iron permease
KAM345_017190	COG2308	Evidence 4 Homologs of previously reported genes of
KAM345_017200	COG0659	secondary active sulfate transmembrane transporter activity
KAM345_017230	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KAM345_017250	COG0326	Molecular chaperone. Has ATPase activity
KAM345_017260	COG0563	adenylate kinase activity
KAM345_017270	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KAM345_017280	COG3788	relative of glutathione S-transferase, MAPEG superfamily
KAM345_017290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM345_017300	COG0840	transmembrane signaling receptor activity
KAM345_017330	COG3300	MHYT domain
KAM345_017330	COG5001	Diguanylate cyclase
KAM345_017380	COG1021	2,3-dihydroxybenzoate-AMP ligase
KAM345_017390	COG1535	isochorismatase
KAM345_017390	COG3433	isochorismatase activity
KAM345_017400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KAM345_017410	COG1028	Short-chain dehydrogenase reductase Sdr
KAM345_017430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KAM345_017470	COG1120	ATPase activity
KAM345_017480	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAM345_017490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAM345_017500	COG4771	TonB-dependent receptor
KAM345_017580	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KAM345_017590	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KAM345_017600	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAM345_017620	COG0861	Integral membrane protein TerC family
KAM345_017650	COG1022	Amp-dependent synthetase and ligase
KAM345_017660	COG0295	cytidine deaminase activity
KAM345_017670	COG1346	cytolysis
KAM345_017680	COG1380	Effector of murein hydrolase LrgA
KAM345_017690	COG3345	alpha-galactosidase
KAM345_017710	COG2925	Exonuclease
KAM345_017730	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KAM345_017740	COG0392	lysyltransferase activity
KAM345_017740	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KAM345_017770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KAM345_017780	COG0436	Aminotransferase
KAM345_017790	COG0583	DNA-binding transcription factor activity
KAM345_017800	COG2160	L-arabinose isomerase activity
KAM345_017820	COG1069	ribulokinase activity
KAM345_017830	COG1879	ABC-type sugar transport system periplasmic component
KAM345_017840	COG1129	ABC transporter
KAM345_017850	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAM345_017870	COG0254	rRNA binding
KAM345_017900	COG1451	nucleotide metabolic process
KAM345_017930	COG3069	C4-dicarboxylate transmembrane transporter activity
KAM345_017950	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KAM345_017950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAM345_017960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KAM345_018000	COG2009	succinate dehydrogenase
KAM345_018010	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KAM345_018040	COG0567	Dehydrogenase, E1 component
KAM345_018050	COG0508	dehydrogenase complex catalyzes the overall conversion of
KAM345_018060	COG0045	succinate-CoA ligase (ADP-forming) activity
KAM345_018070	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KAM345_018090	COG4584	PFAM Integrase catalytic
KAM345_018100	COG1484	DNA-dependent DNA replication
KAM345_018110	COG2801	Transposase and inactivated derivatives
KAM345_018110	COG3415	Transposase
KAM345_018150	COG2983	Belongs to the UPF0260 family
KAM345_018160	COG1882	Formate acetyltransferase
KAM345_018170	COG2116	formate transmembrane transporter activity
KAM345_018180	COG1944	ATP diphosphatase activity
KAM345_018200	COG2076	Multidrug Resistance protein
KAM345_018210	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KAM345_018220	COG1278	Cold shock
KAM345_018230	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KAM345_018240	COG0542	response to heat
KAM345_018250	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KAM345_018260	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KAM345_018270	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KAM345_018280	COG3134	Outer membrane lipoprotein
KAM345_018290	COG3706	GGDEF domain
KAM345_018300	COG0492	ferredoxin-NADP+ reductase activity
KAM345_018310	COG0686	Belongs to the AlaDH PNT family
KAM345_018330	COG0531	amino acid
KAM345_018330	COG1674	ftsk spoiiie
KAM345_018340	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KAM345_018350	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KAM345_018360	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KAM345_018370	COG1286	toxin biosynthetic process
KAM345_018380	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KAM345_018390	COG2723	6-phospho-beta-galactosidase activity
KAM345_018400	COG1263	PTS System
KAM345_018400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM345_018410	COG1609	Transcriptional regulator
KAM345_018430	COG4172	Belongs to the ABC transporter superfamily
KAM345_018450	COG4171	peptide transport system, permease
KAM345_018490	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KAM345_018500	COG1842	Phage shock protein A
KAM345_018530	COG3106	COG3106 Predicted ATPase
KAM345_018540	COG3768	UPF0283 membrane protein
KAM345_018560	COG2154	pterin-4-alpha-carbinolamine dehydratase
KAM345_018600	COG2885	chlorophyll binding
KAM345_018620	COG1570	exodeoxyribonuclease VII activity
KAM345_018650	COG1874	Beta-galactosidase
KAM345_018650	COG0366	Alpha amylase catalytic
KAM345_018670	COG0517	IMP dehydrogenase activity
KAM345_018670	COG0516	GMP reductase activity
KAM345_018680	COG0519	Catalyzes the synthesis of GMP from XMP
KAM345_018680	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KAM345_018790	COG1846	Transcriptional regulator
KAM345_018840	COG1025	Belongs to the peptidase M16 family
KAM345_018850	COG2062	phosphohistidine phosphatase, SixA
KAM345_018870	COG0697	spore germination
KAM345_018890	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
KAM345_018900	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KAM345_018920	COG4591	ABC-type transport system involved in lipoprotein release permease component
KAM345_018930	COG1136	(ABC) transporter
KAM345_018940	COG4591	ABC-type transport system involved in lipoprotein release permease component
KAM345_018950	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KAM345_018980	COG0544	peptidyl-prolyl cis-trans isomerase activity
KAM345_018990	COG0740	serine-type endopeptidase activity
KAM345_019000	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KAM345_019010	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KAM345_019020	COG0776	regulation of translation
KAM345_019030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KAM345_019040	COG0488	(ABC) transporter
KAM345_019050	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KAM345_019060	COG3162	membrane
KAM345_019090	COG1024	Enoyl-CoA hydratase
KAM345_019100	COG1115	amino acid carrier protein
KAM345_019120	COG3228	Belongs to the MtfA family
KAM345_019130	COG1584	GPR1 FUN34 yaaH family protein
KAM345_019180	COG1024	Enoyl-CoA hydratase
KAM345_019190	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KAM345_019200	COG1960	acyl-CoA dehydrogenase activity
KAM345_019220	COG1960	acyl-CoA dehydrogenase activity
KAM345_019230	COG1024	Enoyl-CoA hydratase
KAM345_019240	COG1024	Enoyl-CoA hydratase
KAM345_019260	COG1028	Short-chain dehydrogenase reductase Sdr
KAM345_019280	COG0730	response to heat
KAM345_019310	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KAM345_019390	COG2003	Belongs to the UPF0758 family
KAM345_019430	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM345_019470	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAM345_019480	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAM345_019490	COG1129	ABC transporter
KAM345_019500	COG1879	ABC-type sugar transport system periplasmic component
KAM345_019510	COG0583	DNA-binding transcription factor activity
KAM345_019540	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KAM345_019550	COG0243	molybdopterin cofactor binding
KAM345_019570	COG0583	DNA-binding transcription factor activity
KAM345_019580	COG2723	6-phospho-beta-galactosidase activity
KAM345_019600	COG1484	DNA-dependent DNA replication
KAM345_019610	COG4584	PFAM Integrase catalytic
KAM345_019620	COG0583	DNA-binding transcription factor activity
KAM345_019650	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KAM345_019660	COG0673	inositol 2-dehydrogenase activity
KAM345_019670	COG0583	DNA-binding transcription factor activity
KAM345_019690	COG1560	Kdo2-lipid A biosynthetic process
KAM345_019700	COG1560	Kdo2-lipid A biosynthetic process
KAM345_019730	COG0417	DNA replication proofreading
KAM345_019740	COG0534	Mate efflux family protein
KAM345_019760	COG0307	riboflavin synthase, alpha
KAM345_019790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAM345_019800	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KAM345_019810	COG0697	spore germination
KAM345_019820	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KAM345_019880	COG0675	Transposase, IS605 OrfB family
KAM345_019890	COG2996	Protein conserved in bacteria
KAM345_019920	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KAM345_019930	COG3099	Belongs to the UPF0263 family
KAM345_019940	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KAM345_019950	COG2894	cell division
KAM345_019960	COG0850	regulation of cytokinetic process
KAM345_019970	COG3100	YcgL domain-containing protein
KAM345_019980	COG2951	lytic endotransglycosylase activity
KAM345_019990	COG1760	l-serine dehydratase
KAM345_020000	COG1760	l-serine dehydratase
KAM345_020010	COG3123	guanosine phosphorylase activity
KAM345_020020	COG1301	dicarboxylic acid transport
KAM345_020040	COG1301	dicarboxylic acid transport
KAM345_020070	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KAM345_020080	COG2067	long-chain fatty acid transport protein
KAM345_020090	COG2067	long-chain fatty acid transport protein
KAM345_020110	COG1595	DNA-templated transcription, initiation
KAM345_020170	COG0714	Associated with various cellular activities
KAM345_020180	COG0183	Belongs to the thiolase family
KAM345_020190	COG1024	Enoyl-CoA hydratase
KAM345_020190	COG1250	3-hydroxyacyl-CoA dehydrogenase
KAM345_020210	COG4681	YaeQ
KAM345_020230	COG3039	Transposase
KAM345_020260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAM345_020290	COG3134	Outer membrane lipoprotein
KAM345_020300	COG0318	PFAM AMP-dependent synthetase and ligase
KAM345_020320	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KAM345_020320	COG0140	phosphoribosyl-ATP diphosphatase activity
KAM345_020330	COG0107	imidazoleglycerol-phosphate synthase activity
KAM345_020340	COG2205	protein histidine kinase activity
KAM345_020340	COG0784	Response regulator, receiver
KAM345_020340	COG2198	Histidine kinase
KAM345_020360	COG3437	response regulator, receiver
KAM345_020370	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KAM345_020380	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KAM345_020390	COG0131	Imidazoleglycerol-phosphate dehydratase
KAM345_020390	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KAM345_020400	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KAM345_020410	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KAM345_020420	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KAM345_020440	COG1199	ATP-dependent helicase activity
KAM345_020450	COG1214	PFAM Peptidase M22, glycoprotease
KAM345_020470	COG0596	Alpha beta hydrolase
KAM345_020480	COG0318	PFAM AMP-dependent synthetase and ligase
KAM345_020510	COG0697	spore germination
KAM345_020530	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KAM345_020540	COG2832	Protein of unknown function (DUF454)
KAM345_020550	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KAM345_020570	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KAM345_020580	COG0583	DNA-binding transcription factor activity
KAM345_020600	COG3314	Sporulation integral membrane protein YlbJ
KAM345_020610	COG2197	response regulator
KAM345_020620	COG0517	IMP dehydrogenase activity
KAM345_020620	COG0617	tRNA 3'-terminal CCA addition
KAM345_020620	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KAM345_020630	COG1643	Atp-dependent helicase
KAM345_020650	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KAM345_020660	COG2205	protein histidine kinase activity
KAM345_020660	COG0784	Response regulator, receiver
KAM345_020660	COG5002	protein histidine kinase activity
KAM345_020670	COG2205	protein histidine kinase activity
KAM345_020670	COG3850	Histidine kinase
KAM345_020670	COG4999	Histidine kinase
KAM345_020670	COG3437	response regulator, receiver
KAM345_020710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KAM345_020720	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
KAM345_020730	COG0709	Synthesizes selenophosphate from selenide and ATP
KAM345_020760	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KAM345_020770	COG0840	transmembrane signaling receptor activity
KAM345_020780	COG1254	Belongs to the acylphosphatase family
KAM345_020810	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM345_020810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM345_020820	COG0489	protein tyrosine kinase activity
KAM345_020830	COG0572	uridine kinase
KAM345_020840	COG0717	Belongs to the dCTP deaminase family
KAM345_020850	COG0306	phosphate transporter
KAM345_020880	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM345_020990	COG2948	multi-organism process
KAM345_021010	COG0583	DNA-binding transcription factor activity
KAM345_021020	COG1846	Transcriptional regulator
KAM345_021060	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KAM345_021100	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KAM345_021120	COG0583	DNA-binding transcription factor activity
KAM345_021140	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KAM345_021150	COG0625	glutathione transferase activity
KAM345_021300	COG2801	Transposase and inactivated derivatives
KAM345_021330	COG3385	transposase activity
KAM345_021390	COG3328	transposase activity
KAM345_021400	COG1530	ribonuclease E activity
KAM345_021410	COG0564	pseudouridine synthase activity
KAM345_021450	COG1399	metal-binding, possibly nucleic acid-binding protein
KAM345_021460	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KAM345_021470	COG0416	fatty acid biosynthetic process
KAM345_021480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KAM345_021500	COG1028	Short-chain dehydrogenase reductase Sdr
KAM345_021510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KAM345_021520	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KAM345_021530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KAM345_021540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KAM345_021550	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KAM345_021560	COG0470	DNA polymerase III
KAM345_021570	COG0084	hydrolase, TatD family'
KAM345_021600	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KAM345_021600	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
KAM345_021620	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KAM345_021620	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
KAM345_021630	COG3008	intermembrane lipid transfer
KAM345_021640	COG2995	paraquat-inducible protein a
KAM345_021660	COG3141	response to X-ray
KAM345_021680	COG1067	ATP-dependent peptidase activity
KAM345_021690	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KAM345_021710	COG0488	(ABC) transporter
KAM345_021730	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KAM345_021730	COG0116	Belongs to the methyltransferase superfamily
KAM345_021750	COG0167	dihydroorotate dehydrogenase activity
KAM345_021760	COG2902	Dehydrogenase
KAM345_021780	COG0308	aminopeptidase N
KAM345_021800	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
KAM345_021810	COG1956	GAF domain-containing protein
KAM345_021830	COG3278	Belongs to the heme-copper respiratory oxidase family
KAM345_021860	COG2010	Cytochrome c
KAM345_021880	COG2217	Heavy metal translocating P-type atpase
KAM345_021910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KAM345_021920	COG0589	response to stress
KAM345_021930	COG0037	tRNA processing
KAM345_021960	COG0625	glutathione transferase activity
KAM345_021970	COG1869	D-ribose catabolic process
KAM345_021980	COG1129	ABC transporter
KAM345_021990	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAM345_022000	COG1879	ABC-type sugar transport system periplasmic component
KAM345_022010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM345_022020	COG1609	Transcriptional regulator
KAM345_022050	COG5001	Diguanylate cyclase
KAM345_022050	COG3300	MHYT domain
KAM345_022120	COG0776	regulation of translation
KAM345_022130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM345_022130	COG0072	phenylalanine-tRNA ligase activity
KAM345_022140	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KAM345_022150	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KAM345_022160	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KAM345_022170	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KAM345_022180	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KAM345_022270	COG5433	transposase activity
KAM345_022290	COG5433	transposase activity
KAM345_022320	COG0675	Transposase, IS605 OrfB family
KAM345_022370	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KAM345_022390	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KAM345_022400	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KAM345_022410	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KAM345_022420	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
KAM345_022430	COG3313	Fe-S protein
KAM345_022440	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KAM345_022440	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KAM345_022440	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KAM345_022450	COG1105	Belongs to the carbohydrate kinase PfkB family
KAM345_022460	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM345_022460	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM345_022470	COG1609	Transcriptional regulator
KAM345_022480	COG0814	amino acid
KAM345_022500	COG5654	RES domain protein
KAM345_022510	COG0513	Belongs to the DEAD box helicase family
KAM345_022530	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KAM345_022540	COG2890	protein-(glutamine-N5) methyltransferase activity
KAM345_022550	COG2840	Smr protein MutS2
KAM345_022640	COG2824	Alkylphosphonate utilization operon protein PhnA
KAM345_022680	COG0675	Transposase, IS605 OrfB family
KAM345_022770	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KAM345_022780	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
KAM345_022800	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KAM345_022810	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KAM345_022830	COG0205	6-phosphofructokinase activity
KAM345_022850	COG1473	amidohydrolase
KAM345_022860	COG1011	Hydrolase
KAM345_022870	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KAM345_022890	COG3593	DNA synthesis involved in DNA repair
KAM345_022920	COG0583	DNA-binding transcription factor activity
KAM345_022930	COG0730	response to heat
KAM345_022940	COG3148	PFAM DTW domain containing protein
KAM345_022950	COG1181	Belongs to the D-alanine--D-alanine ligase family
KAM345_022970	COG0386	Belongs to the glutathione peroxidase family
KAM345_022980	COG0513	Belongs to the DEAD box helicase family
KAM345_023010	COG1742	UPF0060 membrane protein
KAM345_023060	COG2329	Antibiotic biosynthesis monooxygenase
KAM345_023070	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KAM345_023110	COG3243	poly(R)-hydroxyalkanoic acid synthase
KAM345_023130	COG2501	S4 domain
KAM345_023160	COG1132	(ABC) transporter
KAM345_023170	COG1132	(ABC) transporter
KAM345_023190	COG3118	belongs to the thioredoxin family
KAM345_023200	COG0471	metal ion transport
KAM345_023220	COG0058	SHG alpha-glucan phosphorylase activity
KAM345_023280	COG0814	amino acid
KAM345_023290	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KAM345_023300	COG0514	ATP-dependent DNA helicase (RecQ)
KAM345_023310	COG2766	serine protein kinase
KAM345_023320	COG2718	Belongs to the UPF0229 family
KAM345_023330	COG2719	SpoVR family
KAM345_023340	COG2186	Transcriptional regulator
KAM345_023350	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KAM345_023360	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KAM345_023370	COG0586	Pfam SNARE associated Golgi protein
KAM345_023390	COG0556	nucleotide-excision repair
KAM345_023400	COG0569	domain protein
KAM345_023400	COG2985	domain, Protein
KAM345_023420	COG0739	heme binding
KAM345_023420	COG0741	lytic transglycosylase activity
KAM345_023420	COG1196	nuclear chromosome segregation
KAM345_023430	COG0675	Transposase, IS605 OrfB family
KAM345_023450	COG3181	Tripartite tricarboxylate transporter family receptor
KAM345_023480	COG4565	transcriptional regulatory protein
KAM345_023490	COG3290	protein histidine kinase activity
KAM345_023500	COG1940	carbohydrate kinase activity
KAM345_023500	COG1846	Transcriptional regulator
KAM345_023510	COG0840	transmembrane signaling receptor activity
KAM345_023530	COG3012	SEC-C Motif Domain Protein
KAM345_023540	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KAM345_023550	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KAM345_023560	COG0247	lactate metabolic process
KAM345_023600	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
KAM345_023610	COG0437	4 iron, 4 sulfur cluster binding
KAM345_023620	COG3301	Polysulphide reductase, NrfD
KAM345_023630	COG1138	Cytochrome C-type biogenesis protein
KAM345_023640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KAM345_023650	COG4235	cytochrome complex assembly
KAM345_023650	COG3088	subunit of a heme lyase
KAM345_023670	COG3046	protein related to deoxyribodipyrimidine photolyase
KAM345_023680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAM345_023710	COG0517	IMP dehydrogenase activity
KAM345_023710	COG0617	tRNA 3'-terminal CCA addition
KAM345_023710	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KAM345_023730	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KAM345_023740	COG0583	DNA-binding transcription factor activity
KAM345_023760	COG4774	siderophore transport
KAM345_023770	COG3706	GGDEF domain
KAM345_023780	COG2200	EAL domain
KAM345_023790	COG4977	sequence-specific DNA binding
KAM345_023790	COG1917	Cupin 2, conserved barrel domain protein
KAM345_023800	COG0583	DNA-binding transcription factor activity
KAM345_023810	COG2910	NAD(P)H-binding
KAM345_023840	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KAM345_023850	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
KAM345_023880	COG2723	6-phospho-beta-galactosidase activity
KAM345_023890	COG1263	PTS System
KAM345_023890	COG2190	(PTS) system
KAM345_023890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM345_023900	COG1737	Transcriptional regulator
KAM345_023940	COG1435	thymidine kinase activity
KAM345_023950	COG1757	Na H antiporter
KAM345_023960	COG2916	Histone family protein nucleoid-structuring protein H-NS
KAM345_023970	COG2096	Adenosyltransferase
KAM345_023980	COG3530	Putative quorum-sensing-regulated virulence factor
KAM345_023990	COG0602	queuosine metabolic process
KAM345_024000	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KAM345_024040	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KAM345_024060	COG0776	regulation of translation
KAM345_024070	COG0539	negative regulation of cytoplasmic translation
KAM345_024080	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KAM345_024090	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KAM345_024150	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KAM345_024160	COG5001	Diguanylate cyclase
KAM345_024160	COG3300	MHYT domain
KAM345_024180	COG0583	DNA-binding transcription factor activity
KAM345_024190	COG0745	RESPONSE REGULATOR receiver
KAM345_024240	COG4989	oxidoreductase activity
KAM345_024250	COG0724	RNA recognition motif
KAM345_024270	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
KAM345_024290	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KAM345_024400	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KAM345_024410	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KAM345_024460	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KAM345_024470	COG1360	Flagellar Motor Protein
KAM345_024480	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM345_024490	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM345_024500	COG0649	NAD binding
KAM345_024500	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM345_024530	COG1034	ATP synthesis coupled electron transport
KAM345_024540	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KAM345_024550	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM345_024560	COG0839	Belongs to the complex I subunit 6 family
KAM345_024570	COG0713	ATP synthesis coupled electron transport
KAM345_024590	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM345_024600	COG1007	ATP synthesis coupled electron transport
KAM345_024610	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KAM345_024610	COG0047	phosphoribosylformylglycinamidine synthase activity
KAM345_024620	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KAM345_024640	COG1645	bacterial-type flagellum-dependent swarming motility
KAM345_024650	COG1160	GTP binding
KAM345_024660	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAM345_024670	COG2976	Protein conserved in bacteria
KAM345_024680	COG0124	histidyl-tRNA synthetase
KAM345_024700	COG1426	Protein conserved in bacteria
KAM345_024720	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KAM345_024730	COG0105	UTP biosynthetic process
KAM345_024760	COG0633	Ferredoxin
KAM345_024770	COG0443	Heat shock 70 kDa protein
KAM345_024780	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KAM345_024800	COG0822	iron-sulfur transferase activity
KAM345_024810	COG1104	cysteine desulfurase activity
KAM345_024840	COG3154	lipid carrier protein
KAM345_024850	COG0826	peptidase U32
KAM345_024860	COG0826	peptidase U32
KAM345_024880	COG2897	thiosulfate sulfurtransferase activity
KAM345_024890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAM345_024900	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAM345_024910	COG1862	Preprotein translocase
KAM345_024920	COG0343	queuine tRNA-ribosyltransferase activity
KAM345_024930	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KAM345_024940	COG0517	IMP dehydrogenase activity
KAM345_024950	COG0450	alkyl hydroperoxide reductase
KAM345_024960	COG3634	alkyl hydroperoxide reductase activity
KAM345_025010	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KAM345_025010	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KAM345_025020	COG0509	glycine decarboxylation via glycine cleavage system
KAM345_025030	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KAM345_025040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KAM345_025050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KAM345_025080	COG2814	Major facilitator Superfamily
KAM345_025090	COG0444	Belongs to the ABC transporter superfamily
KAM345_025100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAM345_025110	COG0601	transmembrane transport
KAM345_025130	COG0625	glutathione transferase activity
KAM345_025140	COG0625	glutathione transferase activity
KAM345_025160	COG0483	inositol monophosphate 1-phosphatase activity
KAM345_025190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KAM345_025200	COG2056	Na+-H+ antiporter family
KAM345_025210	COG2814	Major facilitator Superfamily
KAM345_025220	COG0583	DNA-binding transcription factor activity
KAM345_025230	COG5001	Diguanylate cyclase
KAM345_025260	COG2050	protein possibly involved in aromatic compounds catabolism
KAM345_025280	COG0247	lactate metabolic process
KAM345_025280	COG0277	FAD linked oxidase domain protein
KAM345_025310	COG1253	flavin adenine dinucleotide binding
KAM345_025320	COG1902	pentaerythritol trinitrate reductase activity
KAM345_025340	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KAM345_025350	COG0647	UMP catabolic process
KAM345_025370	COG0367	asparagine synthase
KAM345_025400	COG0625	glutathione transferase activity
KAM345_025420	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KAM345_025450	COG0564	pseudouridine synthase activity
KAM345_025460	COG5001	Diguanylate cyclase
KAM345_025480	COG0840	transmembrane signaling receptor activity
KAM345_025490	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KAM345_025570	COG0670	Belongs to the BI1 family
KAM345_025580	COG1289	transmembrane transporter activity
KAM345_025590	COG2920	part of a sulfur-relay system
KAM345_025600	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
KAM345_025610	COG0285	dihydrofolate synthase activity
KAM345_025620	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KAM345_025630	COG0101	tRNA pseudouridine synthase activity
KAM345_025650	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KAM345_025660	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KAM345_025680	COG1464	Belongs to the NlpA lipoprotein family
KAM345_025730	COG1119	ATPase activity
KAM345_025740	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KAM345_025740	COG0574	Belongs to the PEP-utilizing enzyme family
KAM345_025750	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KAM345_025770	COG1113	amino acid transport
KAM345_025880	COG1242	4 iron, 4 sulfur cluster binding
KAM345_025890	COG0070	glutamate synthase
KAM345_025890	COG0069	glutamate synthase activity
KAM345_025890	COG0067	glutamate synthase
KAM345_025900	COG0493	'glutamate synthase
KAM345_025940	COG4104	PAAR repeat-containing protein
KAM345_025960	COG0513	Belongs to the DEAD box helicase family
KAM345_026020	COG3706	GGDEF domain
KAM345_026030	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KAM345_026040	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KAM345_026050	COG0505	Belongs to the CarA family
KAM345_026060	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KAM345_026080	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KAM345_026090	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KAM345_026100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KAM345_026110	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KAM345_026120	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAM345_026130	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
KAM345_026140	COG4139	cobalamin transport
KAM345_026190	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KAM345_026210	COG0023	Translation Initiation Factor
KAM345_026220	COG2119	membrane
KAM345_026290	COG2199	diguanylate cyclase activity
KAM345_026290	COG2203	Gaf domain
KAM345_026380	COG1196	nuclear chromosome segregation
KAM345_026440	COG0215	cysteine-tRNA ligase activity
KAM345_026450	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KAM345_026470	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAM345_026480	COG2261	transglycosylase associated protein
KAM345_026490	COG1309	transcriptional regulator
KAM345_026500	COG0604	alcohol dehydrogenase
KAM345_026520	COG0402	S-adenosylhomocysteine deaminase activity
KAM345_026580	COG3039	Transposase
KAM345_026590	COG5433	transposase activity
KAM345_026610	COG0582	viral genome integration into host DNA
KAM345_026630	COG5433	transposase activity
KAM345_026650	COG5433	transposase activity
KAM345_026680	COG4584	PFAM Integrase catalytic
KAM345_026690	COG1484	DNA-dependent DNA replication
KAM345_026850	COG0322	excinuclease ABC activity
KAM345_026860	COG2197	response regulator
KAM345_026870	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KAM345_026880	COG2835	tetraacyldisaccharide 4'-kinase activity
KAM345_026890	COG1663	tetraacyldisaccharide 4'-kinase activity
KAM345_026900	COG1132	(ABC) transporter
KAM345_026910	COG0658	competence protein
KAM345_026910	COG2333	competence protein COMEC
KAM345_026940	COG0433	COG0433 Predicted ATPase
KAM345_026950	COG1448	Aminotransferase
KAM345_026980	COG5433	transposase activity
KAM345_027000	COG1199	ATP-dependent helicase activity
KAM345_027020	COG0123	including yeast histone deacetylase and acetoin utilization protein
KAM345_027030	COG0477	Major facilitator Superfamily
KAM345_027040	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KAM345_027050	COG1785	Belongs to the alkaline phosphatase family
KAM345_027100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KAM345_027110	COG3706	GGDEF domain
KAM345_027120	COG0675	Transposase, IS605 OrfB family
KAM345_027140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM345_027150	COG0765	amino acid transport
KAM345_027160	COG1126	abc transporter atp-binding protein
KAM345_027180	COG0531	amino acid
KAM345_027210	COG1253	flavin adenine dinucleotide binding
KAM345_027220	COG0704	Plays a role in the regulation of phosphate uptake
KAM345_027230	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KAM345_027240	COG0581	inorganic phosphate transmembrane transporter activity
KAM345_027250	COG0573	inorganic phosphate transmembrane transporter activity
KAM345_027260	COG0590	tRNA wobble adenosine to inosine editing
KAM345_027280	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KAM345_027320	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KAM345_027330	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KAM345_027340	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KAM345_027350	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KAM345_027400	COG2716	regulation of RNA biosynthetic process
KAM345_027410	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KAM345_027430	COG2239	Acts as a magnesium transporter
KAM345_027470	COG3951	Flagellar rod assembly protein muramidase FlgJ
KAM345_027470	COG1705	Flagellar rod assembly protein muramidase FlgJ
KAM345_027480	COG1706	bacterial-type flagellum-dependent cell motility
KAM345_027490	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KAM345_027520	COG1749	Flagellar hook protein flgE
KAM345_027550	COG1815	bacterial-type flagellum-dependent cell motility
KAM345_027560	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KAM345_027570	COG0835	chemotaxis
KAM345_027570	COG0784	Response regulator, receiver
KAM345_027580	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
KAM345_027610	COG0622	Phosphoesterase
KAM345_027620	COG0675	Transposase, IS605 OrfB family
KAM345_027640	COG4166	transmembrane transport
KAM345_027670	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KAM345_027680	COG0675	Transposase, IS605 OrfB family
KAM345_027700	COG0697	spore germination
KAM345_027760	COG1278	Cold shock
KAM345_027790	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KAM345_027840	COG3132	Protein of unknown function, DUF480
KAM345_027860	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAM345_027900	COG0297	glycogen (starch) synthase activity
KAM345_027910	COG1215	transferase activity, transferring glycosyl groups
KAM345_027930	COG3039	Transposase
KAM345_027940	COG0463	Glycosyl transferase, family 2
KAM345_027980	COG3335	DDE superfamily endonuclease
KAM345_028030	COG4584	PFAM Integrase catalytic
KAM345_028040	COG1484	DNA-dependent DNA replication
KAM345_028110	COG1484	DNA-dependent DNA replication
KAM345_028120	COG4584	PFAM Integrase catalytic
KAM345_028140	COG1091	dTDP-4-dehydrorhamnose reductase activity
KAM345_028170	COG1484	DNA-dependent DNA replication
KAM345_028180	COG4584	PFAM Integrase catalytic
KAM345_028210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KAM345_028240	COG0529	Catalyzes the synthesis of activated sulfate
KAM345_028250	COG0471	metal ion transport
KAM345_028250	COG0490	domain, Protein
KAM345_028260	COG2895	sulfate adenylyltransferase (ATP) activity
KAM345_028320	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KAM345_028340	COG1450	Type ii and iii secretion system protein
KAM345_028410	COG2165	general secretion pathway protein
KAM345_028430	COG1459	type II secretion system
KAM345_028480	COG1091	dTDP-4-dehydrorhamnose reductase activity
KAM345_028520	COG3039	Transposase
KAM345_028530	COG3039	Transposase
KAM345_028570	COG1737	Transcriptional regulator
KAM345_028580	COG0469	pyruvate kinase activity
KAM345_028600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM345_028610	COG1960	acyl-CoA dehydrogenase activity
KAM345_028630	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KAM345_028660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM345_028670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM345_028680	COG1309	transcriptional regulator
KAM345_028710	COG1946	Acyl-CoA thioesterase
KAM345_028740	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KAM345_028760	COG0009	L-threonylcarbamoyladenylate synthase
KAM345_028770	COG0613	PHP domain protein
KAM345_028780	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KAM345_028790	COG0512	Glutamine amidotransferase of anthranilate synthase
KAM345_028790	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KAM345_028800	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KAM345_028810	COG0134	indole-3-glycerol-phosphate synthase activity
KAM345_028810	COG0135	phosphoribosylanthranilate isomerase activity
KAM345_028820	COG0133	tryptophan synthase activity
KAM345_028830	COG0159	tryptophan synthase activity
KAM345_028860	COG1988	membrane-bound metal-dependent
KAM345_028890	COG1396	sequence-specific DNA binding
KAM345_028900	COG3550	peptidyl-serine autophosphorylation
KAM345_028940	COG0583	DNA-binding transcription factor activity
KAM345_028960	COG4521	taurine ABC transporter
KAM345_028970	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KAM345_028980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KAM345_028990	COG2175	clavaminate synthase activity
KAM345_029000	COG5507	3-demethylubiquinone-9 3-methyltransferase
KAM345_029010	COG2814	Major facilitator Superfamily
KAM345_029020	COG0109	protoheme IX farnesyltransferase activity
KAM345_029030	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KAM345_029040	COG1845	cytochrome c oxidase, subunit III
KAM345_029050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KAM345_029060	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KAM345_029070	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KAM345_029080	COG0583	DNA-binding transcription factor activity
KAM345_029120	COG1846	Transcriptional regulator
KAM345_029150	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
KAM345_029180	COG0745	RESPONSE REGULATOR receiver
KAM345_029200	COG0708	Exodeoxyribonuclease III
KAM345_029220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM345_029230	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM345_029260	COG0095	Lipoate-protein ligase
KAM345_029320	COG0640	Transcriptional regulator
KAM345_029340	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAM345_029360	COG1285	pathogenesis
KAM345_029430	COG0484	heat shock protein binding
KAM345_029440	COG0443	Heat shock 70 kDa protein
KAM345_029450	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KAM345_029460	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KAM345_029470	COG3706	GGDEF domain
KAM345_029480	COG0497	DNA recombination
KAM345_029500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM345_029510	COG1136	(ABC) transporter
KAM345_029510	COG0577	efflux transmembrane transporter activity
KAM345_029520	COG1538	Outer membrane efflux protein
KAM345_029530	COG2375	cellular response to nickel ion
KAM345_029540	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAM345_029550	COG2916	Histone family protein nucleoid-structuring protein H-NS
KAM345_029560	COG0583	DNA-binding transcription factor activity
KAM345_029570	COG3048	D-serine ammonia-lyase activity
KAM345_029590	COG0538	isocitrate dehydrogenase activity
KAM345_029670	COG0456	acetyltransferase
KAM345_029680	COG1187	pseudouridine synthase activity
KAM345_029700	COG0482	sulfurtransferase activity
KAM345_029710	COG2915	High frequency lysogenization protein hflD homolog
KAM345_029720	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KAM345_029730	COG2850	peptidyl-arginine hydroxylation
KAM345_029750	COG3264	Mechanosensitive ion channel
KAM345_029750	COG1196	nuclear chromosome segregation
KAM345_029810	COG0281	malic enzyme
KAM345_029820	COG0746	molybdenum cofactor guanylyltransferase activity
KAM345_029830	COG1763	Mo-molybdopterin cofactor biosynthetic process
KAM345_029840	COG1289	transmembrane transporter activity
KAM345_029850	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KAM345_029910	COG3220	belongs to the UPF0276 family
KAM345_029930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KAM345_030030	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KAM345_030040	COG0083	homoserine kinase activity
KAM345_030060	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
KAM345_030070	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
KAM345_030110	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KAM345_030130	COG0745	RESPONSE REGULATOR receiver
KAM345_030140	COG4988	ABC transporter
KAM345_030150	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KAM345_030190	COG1720	tRNA m6t6A37 methyltransferase activity
KAM345_030220	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KAM345_030230	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KAM345_030240	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM345_030260	COG2190	(PTS) system
KAM345_030270	COG3038	cytochrome b561
KAM345_030290	COG0420	3'-5' exonuclease activity
KAM345_030310	COG1247	-acetyltransferase
KAM345_030320	COG2974	May be involved in recombination
KAM345_030340	COG0405	Gamma-glutamyltransferase
KAM345_030350	COG4651	solute:proton antiporter activity
KAM345_030350	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KAM345_030430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAM345_030440	COG1396	sequence-specific DNA binding
KAM345_030440	COG1917	Cupin 2, conserved barrel domain protein
KAM345_030450	COG1012	belongs to the aldehyde dehydrogenase family
KAM345_030480	COG0531	amino acid
KAM345_030490	COG0531	amino acid
KAM345_030510	COG1283	sodium-dependent phosphate transmembrane transporter activity
KAM345_030530	COG3384	dioxygenase
KAM345_030540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM345_030540	COG2205	protein histidine kinase activity
KAM345_030550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM345_030550	COG2198	Histidine kinase
KAM345_030550	COG0784	Response regulator, receiver
KAM345_030550	COG2205	protein histidine kinase activity
KAM345_030580	COG0784	Response regulator, receiver
KAM345_030580	COG2205	protein histidine kinase activity
KAM345_030590	COG0582	viral genome integration into host DNA
KAM345_030600	COG4584	PFAM Integrase catalytic
KAM345_030610	COG1484	DNA-dependent DNA replication
KAM345_030630	COG3311	Transcriptional regulator
KAM345_030650	COG3385	transposase activity
KAM345_030700	COG2801	Transposase and inactivated derivatives
KAM345_030720	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
KAM345_030740	COG5377	YqaJ viral recombinase family
KAM345_030800	COG2003	Belongs to the UPF0758 family
KAM345_030810	COG3385	transposase activity
KAM345_030880	COG0515	serine threonine protein kinase
KAM345_030950	COG1388	LysM domain
KAM345_030950	COG1376	ErfK ybiS ycfS ynhG family protein
KAM345_030980	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
KAM345_030990	COG0791	NLP P60 protein
KAM345_031010	COG3118	belongs to the thioredoxin family
KAM345_031030	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KAM345_031040	COG0788	formyltetrahydrofolate deformylase activity
KAM345_031090	COG1196	nuclear chromosome segregation
KAM345_031090	COG0741	lytic transglycosylase activity
KAM345_031090	COG0739	heme binding
KAM345_031100	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KAM345_031110	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KAM345_031120	COG0673	inositol 2-dehydrogenase activity
KAM345_031180	COG1032	radical SAM domain protein
KAM345_031190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM345_031210	COG3706	GGDEF domain
KAM345_031220	COG1752	Esterase of the alpha-beta hydrolase superfamily
KAM345_031230	COG0733	neurotransmitter:sodium symporter activity
KAM345_031300	COG0281	malic enzyme
KAM345_031310	COG2207	Transcriptional regulator
KAM345_031350	COG2233	PERMEase
KAM345_031360	COG0095	Lipoate-protein ligase
KAM345_031370	COG1115	amino acid carrier protein
KAM345_031380	COG0019	diaminopimelate decarboxylase activity
KAM345_031400	COG0678	peroxiredoxin activity
KAM345_031410	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KAM345_031430	COG1126	abc transporter atp-binding protein
KAM345_031440	COG0765	amino acid transport
KAM345_031450	COG4597	amino acid ABC transporter
KAM345_031460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM345_031500	COG0545	Peptidyl-prolyl cis-trans isomerase
KAM345_031530	COG3142	Participates in the control of copper homeostasis
KAM345_031540	COG1940	carbohydrate kinase activity
KAM345_031560	COG4783	chaperone-mediated protein folding
KAM345_031580	COG5002	protein histidine kinase activity
KAM345_031590	COG0745	RESPONSE REGULATOR receiver
KAM345_031600	COG0346	lactoylglutathione lyase activity
KAM345_031610	COG3706	GGDEF domain
KAM345_031620	COG3284	Transcriptional regulator
KAM345_031650	COG0697	spore germination
KAM345_031670	COG0667	Aldo Keto reductase
KAM345_031700	COG3290	protein histidine kinase activity
KAM345_031720	COG1566	PFAM secretion protein HlyD family protein
KAM345_031780	COG0602	queuosine metabolic process
KAM345_031790	COG1328	CTP reductase activity
KAM345_031810	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KAM345_031820	COG3115	cell septum assembly
KAM345_031830	COG1196	nuclear chromosome segregation
KAM345_031850	COG2860	membrane
KAM345_031870	COG3108	Peptidase M15
KAM345_031880	COG2989	Protein conserved in bacteria
KAM345_031910	COG0463	Glycosyl transferase, family 2
KAM345_031940	COG0366	Alpha amylase catalytic
KAM345_032030	COG3706	GGDEF domain
KAM345_032040	COG0037	tRNA processing
KAM345_032070	COG0488	(ABC) transporter
KAM345_032090	COG0531	amino acid
KAM345_032100	COG0814	amino acid
KAM345_032130	COG0825	malonyl-CoA metabolic process
KAM345_032140	COG0587	DNA-directed DNA polymerase activity
KAM345_032150	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KAM345_032160	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAM345_032170	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAM345_032180	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KAM345_032190	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAM345_032220	COG0750	zinc metalloprotease
KAM345_032230	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KAM345_032240	COG0575	Belongs to the CDS family
KAM345_032250	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KAM345_032260	COG0233	cytoplasmic translational termination
KAM345_032270	COG0528	UMP kinase activity
KAM345_032280	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KAM345_032290	COG0052	Belongs to the universal ribosomal protein uS2 family
KAM345_032300	COG0024	Methionine aminopeptidase
KAM345_032310	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KAM345_032320	COG2171	N-acyltransferase activity
KAM345_032340	COG1263	PTS System
KAM345_032340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM345_032420	COG0564	pseudouridine synthase activity
KAM345_032430	COG3098	single-species biofilm formation
KAM345_032480	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
KAM345_032500	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KAM345_032500	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KAM345_032530	COG1611	Belongs to the LOG family
KAM345_032550	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KAM345_032560	COG0473	3-isopropylmalate dehydrogenase activity
KAM345_032580	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
KAM345_032610	COG0583	DNA-binding transcription factor activity
KAM345_032620	COG0840	transmembrane signaling receptor activity
KAM345_032630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KAM345_032660	COG1477	protein flavinylation
KAM345_032670	COG2871	sodium ion transport
KAM345_032680	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM345_032690	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM345_032700	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM345_032710	COG1805	sodium ion transport
KAM345_032720	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM345_032730	COG0271	Belongs to the BolA IbaG family
KAM345_032740	COG2813	Specifically methylates the guanine in position
KAM345_032760	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KAM345_032780	COG2211	Major facilitator Superfamily
KAM345_032800	COG1666	GTP binding
KAM345_032810	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KAM345_032830	COG0659	secondary active sulfate transmembrane transporter activity
KAM345_032850	COG5002	protein histidine kinase activity
KAM345_032850	COG5000	phosphorelay sensor kinase activity
KAM345_032870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM345_032880	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM345_032900	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KAM345_032960	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KAM345_032980	COG1151	hydroxylamine reductase activity
KAM345_032990	COG0783	Belongs to the Dps family
KAM345_033040	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KAM345_033070	COG4221	oxidoreductase activity
KAM345_033090	COG0415	Belongs to the DNA photolyase family
KAM345_033100	COG0789	Transcriptional regulator
KAM345_033110	COG3272	Protein of unknown function (DUF1722)
KAM345_033160	COG0077	Prephenate dehydratase
KAM345_033160	COG1605	Chorismate mutase
KAM345_033210	COG5377	YqaJ viral recombinase family
KAM345_033260	COG2003	Belongs to the UPF0758 family
KAM345_033340	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KAM345_033350	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KAM345_033410	COG1484	DNA-dependent DNA replication
KAM345_033420	COG4584	PFAM Integrase catalytic
KAM345_033490	COG3328	transposase activity
KAM345_033520	COG2133	pyrroloquinoline quinone binding
KAM345_033540	COG1349	DNA-binding transcription factor activity
KAM345_033550	COG2084	Dehydrogenase
KAM345_033570	COG0235	Class ii aldolase
KAM345_033580	COG3622	Belongs to the hyi family
KAM345_033590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KAM345_033600	COG2610	gluconate transmembrane transporter activity
KAM345_033650	COG0300	oxidoreductase activity
KAM345_033700	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KAM345_033760	COG0826	peptidase U32
KAM345_033770	COG1280	lysine exporter protein (LysE YggA)
KAM345_033790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KAM345_033810	COG2199	diguanylate cyclase activity
KAM345_033810	COG2200	EAL domain
KAM345_033810	COG2203	Gaf domain
KAM345_033900	COG1566	PFAM secretion protein HlyD family protein
KAM345_033920	COG0114	fumarate hydratase activity
KAM345_033940	COG0506	proline dehydrogenase activity
KAM345_033940	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KAM345_033940	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KAM345_033950	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KAM345_033980	COG0737	Belongs to the 5'-nucleotidase family
KAM345_034020	COG2204	response regulator
KAM345_034030	COG0545	Peptidyl-prolyl cis-trans isomerase
KAM345_034050	COG2900	Belongs to the SlyX family
KAM345_034060	COG1047	Peptidyl-prolyl cis-trans
KAM345_034070	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KAM345_034090	COG0784	Response regulator, receiver
KAM345_034090	COG0835	chemotaxis
KAM345_034100	COG0429	hydrolase of the alpha beta-hydrolase fold
KAM345_034110	COG2203	Gaf domain
KAM345_034110	COG3706	GGDEF domain
KAM345_034110	COG4251	negative regulation of phosphorylation
KAM345_034110	COG5001	Diguanylate cyclase
KAM345_034120	COG3089	Belongs to the UPF0270 family
KAM345_034130	COG3954	Phosphoribulokinase
KAM345_034160	COG1765	OsmC-like protein
KAM345_034180	COG2226	methyltransferase
KAM345_034200	COG2202	Pas domain
KAM345_034200	COG2205	protein histidine kinase activity
KAM345_034210	COG2814	Major facilitator Superfamily
KAM345_034260	COG0748	coenzyme F420 binding
KAM345_034270	COG3721	Heme iron utilization protein
KAM345_034290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAM345_034340	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KAM345_034360	COG0463	Glycosyl transferase, family 2
KAM345_034370	COG0741	lytic transglycosylase activity
KAM345_034370	COG1196	nuclear chromosome segregation
KAM345_034370	COG0739	heme binding
KAM345_034380	COG0488	(ABC) transporter
KAM345_034400	COG2252	PERMEase
KAM345_034410	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KAM345_034420	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KAM345_034430	COG3178	'Phosphotransferase
KAM345_034440	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KAM345_034460	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KAM345_034470	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KAM345_034490	COG2967	ApaG domain
KAM345_034500	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KAM345_034520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KAM345_034540	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KAM345_034550	COG3314	Sporulation integral membrane protein YlbJ
KAM345_034560	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KAM345_034570	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KAM345_034580	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KAM345_034590	COG0142	geranyltranstransferase activity
KAM345_034600	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
KAM345_034610	COG0330	HflC and HflK could
KAM345_034620	COG0330	HflC and HflK could
KAM345_034630	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KAM345_034640	COG1923	regulation of RNA biosynthetic process
KAM345_034650	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KAM345_034660	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KAM345_034680	COG0802	atpase or kinase
KAM345_034690	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KAM345_034690	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KAM345_034730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KAM345_034740	COG2011	ABC-type metal ion transport system permease component
KAM345_034750	COG1464	Belongs to the NlpA lipoprotein family
KAM345_034800	COG0784	Response regulator, receiver
KAM345_034800	COG2205	protein histidine kinase activity
KAM345_034830	COG0784	Response regulator, receiver
KAM345_034830	COG5002	protein histidine kinase activity
KAM345_034830	COG2198	Histidine kinase
KAM345_034870	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
KAM345_034900	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KAM345_034910	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
KAM345_034920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KAM345_034930	COG2716	regulation of RNA biosynthetic process
KAM345_034940	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KAM345_034950	COG3013	Belongs to the UPF0304 family
KAM345_034960	COG3092	negative regulation of chromosome organization
KAM345_034970	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KAM345_034980	COG0857	belongs to the CobB CobQ family
KAM345_034980	COG0280	phosphate acetyltransferase
KAM345_034990	COG0440	acetolactate synthase activity
KAM345_035000	COG0028	Belongs to the TPP enzyme family
KAM345_035020	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KAM345_035030	COG0671	phosphoesterase, PA-phosphatase related
KAM345_035050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KAM345_035060	COG0473	3-isopropylmalate dehydrogenase activity
KAM345_035070	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KAM345_035080	COG0066	3-isopropylmalate dehydratase activity
KAM345_035110	COG4143	(ABC) transporter
KAM345_035120	COG1178	ABC-type Fe3 transport system permease component
KAM345_035130	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
KAM345_035150	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KAM345_035170	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KAM345_035190	COG0316	Belongs to the HesB IscA family
KAM345_035210	COG0038	chloride channel
KAM345_035220	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KAM345_035250	COG0671	phosphoesterase, PA-phosphatase related
KAM345_035270	COG0583	DNA-binding transcription factor activity
KAM345_035280	COG2076	Multidrug Resistance protein
KAM345_035300	COG0346	lactoylglutathione lyase activity
KAM345_035310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KAM345_035320	COG1643	Atp-dependent helicase
KAM345_035340	COG1489	DNA binding
KAM345_035350	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KAM345_035360	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KAM345_035380	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KAM345_035390	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KAM345_035400	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KAM345_035450	COG0842	Transport permease protein
KAM345_035460	COG1131	(ABC) transporter
KAM345_035490	COG0163	prenyltransferase activity
KAM345_035500	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KAM345_035510	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KAM345_035540	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
KAM345_035570	COG1136	(ABC) transporter
KAM345_035680	COG0529	Catalyzes the synthesis of activated sulfate
KAM345_035690	COG0471	metal ion transport
KAM345_035690	COG3273	potassium ion transport
KAM345_035700	COG2895	sulfate adenylyltransferase (ATP) activity
KAM345_035710	COG0175	sulfate reduction
KAM345_035720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KAM345_035720	COG1648	precorrin-2 dehydrogenase activity
KAM345_035730	COG0330	HflC and HflK could
KAM345_035740	COG1585	Membrane protein implicated in regulation of membrane protease activity
KAM345_035770	COG0673	inositol 2-dehydrogenase activity
KAM345_035790	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KAM345_035800	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KAM345_035810	COG3036	rescue of stalled ribosome
KAM345_035840	COG0138	bifunctional purine biosynthesis protein purh
KAM345_035850	COG0151	Belongs to the GarS family
KAM345_035930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KAM345_035940	COG0358	DNA primase activity
KAM345_035950	COG1610	YqeY-like protein
KAM345_035960	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KAM345_035970	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KAM345_036000	COG1388	LysM domain
KAM345_036000	COG4942	peptidase
KAM345_036010	COG1238	metal cluster binding
KAM345_036020	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KAM345_036030	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KAM345_036040	COG0585	pseudouridine synthase activity
KAM345_036060	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KAM345_036070	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KAM345_036080	COG0148	phosphopyruvate hydratase activity
KAM345_036090	COG0504	CTP synthase activity
KAM345_036100	COG3956	TIGRFAM MazG family protein
KAM345_036110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KAM345_036120	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KAM345_036140	COG4807	Protein conserved in bacteria
KAM345_036150	COG3023	N-Acetylmuramoyl-L-alanine amidase
KAM345_036160	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KAM345_036170	COG1381	Involved in DNA repair and RecF pathway recombination
KAM345_036190	COG0571	ribonuclease III activity
KAM345_036200	COG0681	Belongs to the peptidase S26 family
KAM345_036210	COG0481	GTPase activity
KAM345_036250	COG1595	DNA-templated transcription, initiation
KAM345_036260	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KAM345_036280	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KAM345_036290	COG0354	folic acid binding
KAM345_036300	COG0583	DNA-binding transcription factor activity
KAM345_036360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAM345_036380	COG0126	phosphoglycerate kinase activity
KAM345_036390	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KAM345_036400	COG1940	carbohydrate kinase activity
KAM345_036410	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KAM345_036430	COG4991	sh3 domain protein
KAM345_036440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KAM345_036470	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KAM345_036510	COG1028	Short-chain dehydrogenase reductase Sdr
KAM345_036530	COG1505	serine-type exopeptidase activity
KAM345_036540	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KAM345_036550	COG0765	amino acid transport
KAM345_036560	COG0765	amino acid transport
KAM345_036570	COG1126	abc transporter atp-binding protein
KAM345_036580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM345_036590	COG3174	membrane
KAM345_036600	COG0110	maltose O-acetyltransferase activity
KAM345_036660	COG1942	4-Oxalocrotonate Tautomerase
KAM345_036680	COG0583	DNA-binding transcription factor activity
KAM345_036690	COG0165	Argininosuccinate lyase
KAM345_036700	COG0137	argininosuccinate synthase activity
KAM345_036720	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KAM345_036730	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KAM345_036750	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KAM345_036770	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KAM345_036840	COG0583	DNA-binding transcription factor activity
KAM345_036850	COG1380	Effector of murein hydrolase LrgA
KAM345_036860	COG1346	cytolysis
KAM345_036870	COG0460	homoserine dehydrogenase
KAM345_036870	COG0527	aspartate kinase activity
KAM345_036880	COG0626	cystathionine gamma-synthase activity
KAM345_036910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM345_036920	COG0814	amino acid
KAM345_036930	COG1218	3'(2'),5'-bisphosphate nucleotidase
KAM345_036940	COG0494	nUDIX hydrolase
KAM345_036950	COG1011	Hydrolase
KAM345_036980	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KAM345_037010	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
KAM345_037030	COG3156	type II secretion system protein K
KAM345_037040	COG4795	General secretion pathway protein
KAM345_037050	COG2165	general secretion pathway protein
KAM345_037090	COG2165	general secretion pathway protein
KAM345_037100	COG1459	type II secretion system
KAM345_037110	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KAM345_037130	COG3031	protein transport across the cell outer membrane
KAM345_037150	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KAM345_037160	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KAM345_037200	COG3133	Outer membrane lipoprotein
KAM345_037210	COG3025	triphosphatase activity
KAM345_037220	COG1392	Phosphate transport regulator
KAM345_037230	COG0306	phosphate transporter
KAM345_037240	COG0617	tRNA 3'-terminal CCA addition
KAM345_037250	COG3267	Type II secretory pathway component ExeA
KAM345_037250	COG3409	Peptidoglycan-binding domain 1 protein
KAM345_037270	COG1194	a g-specific adenine glycosylase
KAM345_037280	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
KAM345_037310	COG3240	lipase activity
KAM345_037330	COG3009	Protein conserved in bacteria
KAM345_037340	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KAM345_037340	COG3008	intermembrane lipid transfer
KAM345_037350	COG2995	paraquat-inducible protein a
KAM345_037370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAM345_037380	COG5001	Diguanylate cyclase
KAM345_037380	COG4251	negative regulation of phosphorylation
KAM345_037380	COG3706	GGDEF domain
KAM345_037380	COG2203	Gaf domain
KAM345_037390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KAM345_037400	COG2813	Specifically methylates the guanine in position
KAM345_037410	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KAM345_037420	COG0297	glycogen (starch) synthase activity
KAM345_037450	COG1757	Na H antiporter
KAM345_037460	COG0583	DNA-binding transcription factor activity
KAM345_037480	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KAM345_037490	COG3842	ATPase activity
KAM345_037500	COG1176	ABC-type spermidine putrescine transport system, permease component I
KAM345_037510	COG1177	transmembrane transport
KAM345_037520	COG1012	belongs to the aldehyde dehydrogenase family
KAM345_037530	COG0109	protoheme IX farnesyltransferase activity
KAM345_037590	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KAM345_037610	COG1565	acr, cog1565
KAM345_037610	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KAM345_037620	COG1444	tRNA N-acetyltransferase activity
KAM345_037660	COG1803	Methylglyoxal synthase
KAM345_037690	COG0252	asparaginase activity
KAM345_037730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM345_037730	COG1263	PTS System
KAM345_037740	COG0366	Alpha amylase catalytic
KAM345_037750	COG0110	maltose O-acetyltransferase activity
KAM345_037760	COG1522	sequence-specific DNA binding
KAM345_037820	COG3068	Protein conserved in bacteria
KAM345_037840	COG0739	heme binding
KAM345_037880	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
KAM345_037890	COG1121	(ABC) transporter
KAM345_037900	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KAM345_037910	COG0583	DNA-binding transcription factor activity
KAM345_037930	COG1573	uracil-dna glycosylase
KAM345_037940	COG2962	Rard protein
KAM345_037950	COG2827	Endonuclease containing a URI domain
KAM345_037980	COG1842	Phage shock protein A
KAM345_037990	COG0204	Acyl-transferase
KAM345_038030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KAM345_038050	COG0484	heat shock protein binding
KAM345_038160	COG3385	transposase activity
KAM345_038200	COG1289	transmembrane transporter activity
KAM345_038210	COG1566	PFAM secretion protein HlyD family protein
KAM345_038240	COG1051	belongs to the nudix hydrolase family
KAM345_038250	COG3150	esterase
KAM345_038270	COG3151	Protein conserved in bacteria
KAM345_038280	COG0494	nUDIX hydrolase
KAM345_038290	COG1538	Outer membrane efflux protein
KAM345_038300	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KAM345_038300	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KAM345_038310	COG1560	Kdo2-lipid A biosynthetic process
KAM345_038340	COG2771	luxR family
KAM345_038350	COG3916	Acyl-homoserine-lactone synthase
KAM345_038370	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
KAM345_038390	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM345_038390	COG2213	PTS system mannitol-specific
KAM345_038400	COG0246	Mannitol dehydrogenase
KAM345_038410	COG5433	transposase activity
KAM345_038420	COG3722	fumarate hydratase activity
KAM345_038430	COG3263	regulation of cellular component size
KAM345_038470	COG1671	Belongs to the UPF0178 family
KAM345_038510	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KAM345_038520	COG0513	Belongs to the DEAD box helicase family
KAM345_038560	COG1575	Belongs to the MenA family. Type 1 subfamily
KAM345_038570	COG1169	isochorismate synthase
KAM345_038580	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KAM345_038590	COG0596	Alpha beta hydrolase
KAM345_038600	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KAM345_038620	COG0318	PFAM AMP-dependent synthetase and ligase
KAM345_038630	COG3291	Pkd domain containing protein
KAM345_038640	COG2949	membrane
KAM345_038650	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KAM345_038670	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KAM345_038730	COG2873	o-acetylhomoserine
KAM345_038750	COG1979	alcohol dehydrogenase
KAM345_038780	COG4221	oxidoreductase activity
KAM345_038820	COG1285	pathogenesis
KAM345_038850	COG1368	sulfuric ester hydrolase activity
KAM345_038860	COG1522	sequence-specific DNA binding
KAM345_038880	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KAM345_038900	COG1058	Belongs to the CinA family
KAM345_038900	COG1546	Belongs to the CinA family
KAM345_038910	COG1988	membrane-bound metal-dependent
KAM345_038940	COG0561	phosphatase activity
KAM345_038950	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KAM345_038970	COG1011	Hydrolase
KAM345_039000	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KAM345_039010	COG0019	diaminopimelate decarboxylase activity
KAM345_039030	COG1965	Belongs to the frataxin family
KAM345_039040	COG0400	carboxylic ester hydrolase activity
KAM345_039050	COG3072	Adenylate cyclase
KAM345_039060	COG0181	hydroxymethylbilane synthase activity
KAM345_039080	COG2959	enzyme of heme biosynthesis
KAM345_039090	COG3071	HemY protein
KAM345_039110	COG0312	modulator of DNA gyrase
KAM345_039120	COG3028	Belongs to the UPF0307 family
KAM345_039140	COG4584	PFAM Integrase catalytic
KAM345_039150	COG1484	DNA-dependent DNA replication
KAM345_039160	COG2926	Belongs to the UPF0265 family
KAM345_039180	COG1396	sequence-specific DNA binding
KAM345_039190	COG3135	benzoate transporter
KAM345_039250	COG3047	cAMP biosynthetic process
KAM345_039270	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KAM345_039280	COG2197	response regulator
KAM345_039340	COG1278	Cold shock
KAM345_039400	COG3706	GGDEF domain
KAM345_039410	COG0347	Belongs to the P(II) protein family
KAM345_039420	COG0004	ammonium transporteR
KAM345_039440	COG0346	lactoylglutathione lyase activity
KAM345_039450	COG3328	transposase activity
KAM345_039500	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KAM345_039510	COG1074	ATP-dependent DNA helicase activity
KAM345_039520	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KAM345_039530	COG2259	Doxx family
KAM345_039540	COG1741	Belongs to the pirin family
KAM345_039560	COG0583	DNA-binding transcription factor activity
KAM345_039610	COG1175	transmembrane transport
KAM345_039630	COG3842	ATPase activity
KAM345_039690	COG0456	acetyltransferase
KAM345_039700	COG0753	catalase activity
KAM345_039740	COG0494	nUDIX hydrolase
KAM345_039750	COG0628	permease
KAM345_039770	COG2957	Belongs to the agmatine deiminase family
KAM345_039800	COG2957	Belongs to the agmatine deiminase family
KAM345_039810	COG0583	DNA-binding transcription factor activity
KAM345_039840	COG1461	Dihydroxyacetone kinase
KAM345_039850	COG2376	Dihydroxyacetone kinase
KAM345_039860	COG2252	PERMEase
KAM345_039870	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KAM345_039880	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KAM345_039890	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KAM345_039900	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KAM345_039910	COG0049	tRNA binding
KAM345_039920	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KAM345_039930	COG2168	tRNA wobble position uridine thiolation
KAM345_039950	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KAM345_039960	COG0251	oxidation-reduction process
KAM345_039970	COG2964	Protein conserved in bacteria
KAM345_039980	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KAM345_039990	COG0085	RNA polymerase activity
KAM345_040000	COG0222	ribosome binding
KAM345_040010	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KAM345_040020	COG0081	regulation of translation
KAM345_040030	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KAM345_040040	COG0250	Participates in transcription elongation, termination and antitermination
KAM345_040060	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KAM345_040090	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KAM345_040100	COG0569	domain protein
KAM345_040110	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KAM345_040120	COG3385	transposase activity
KAM345_040130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KAM345_040140	COG3005	denitrification pathway
KAM345_040150	COG0243	molybdopterin cofactor binding
KAM345_040240	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KAM345_040260	COG2204	response regulator
KAM345_040280	COG2205	protein histidine kinase activity
KAM345_040300	COG1028	Short-chain dehydrogenase reductase Sdr
KAM345_040330	COG1522	sequence-specific DNA binding
KAM345_040340	COG2502	aspartate--ammonia ligase
KAM345_040360	COG0542	response to heat
KAM345_040380	COG0564	pseudouridine synthase activity
KAM345_040390	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAM345_040400	COG3681	Belongs to the UPF0597 family
KAM345_040410	COG2964	Protein conserved in bacteria
KAM345_040420	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KAM345_040430	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KAM345_040440	COG1979	alcohol dehydrogenase
KAM345_040450	COG2207	Transcriptional regulator
KAM345_040460	COG3040	lipid binding
KAM345_040540	COG0540	Belongs to the ATCase OTCase family
KAM345_040550	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
KAM345_040560	COG1438	arginine binding
KAM345_040570	COG1288	antiporter activity
KAM345_040580	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KAM345_040670	COG3250	beta-galactosidase activity
KAM345_040690	COG1609	Transcriptional regulator
KAM345_040700	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KAM345_040720	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KAM345_040730	COG2017	converts alpha-aldose to the beta-anomer
KAM345_040740	COG0667	Aldo Keto reductase
KAM345_040750	COG1968	undecaprenyl-diphosphatase activity
KAM345_040760	COG3806	Anti-sigma factor
KAM345_040770	COG1595	DNA-templated transcription, initiation
KAM345_040810	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KAM345_040820	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KAM345_040830	COG0477	Major facilitator Superfamily
KAM345_040860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM345_040870	COG1131	(ABC) transporter
KAM345_040880	COG0842	Transport permease protein
KAM345_040890	COG0842	Transport permease protein
KAM345_040900	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KAM345_040920	COG2116	formate transmembrane transporter activity
KAM345_040930	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KAM345_040930	COG1648	precorrin-2 dehydrogenase activity
KAM345_040940	COG2239	Acts as a magnesium transporter
KAM345_040950	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KAM345_040960	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KAM345_040980	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KAM345_041000	COG0514	ATP-dependent DNA helicase (RecQ)
KAM345_041010	COG2050	protein possibly involved in aromatic compounds catabolism
KAM345_041030	COG2258	MOSC domain
KAM345_041040	COG1177	transmembrane transport
KAM345_041050	COG1176	ABC-type spermidine putrescine transport system, permease component I
KAM345_041060	COG3842	ATPase activity
KAM345_041110	COG0174	glutamine synthetase
KAM345_041150	COG3045	CreA protein
KAM345_041160	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KAM345_041170	COG0443	Heat shock 70 kDa protein
KAM345_041200	COG0366	Alpha amylase catalytic
KAM345_041230	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KAM345_041240	COG0745	RESPONSE REGULATOR receiver
KAM345_041250	COG2205	protein histidine kinase activity
KAM345_041270	COG0281	malic enzyme
KAM345_041280	COG0702	epimerase
KAM345_041290	COG0254	rRNA binding
KAM345_041300	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KAM345_041370	COG0129	dihydroxy-acid dehydratase activity
KAM345_041390	COG3978	acetolactate synthase activity
KAM345_041410	COG0606	chelatase, subunit chli
KAM345_041420	COG0204	Acyl-transferase
KAM345_041430	COG0204	Acyl-transferase
KAM345_041440	COG1683	Conserved Protein
KAM345_041460	COG1335	isochorismatase
KAM345_041480	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KAM345_041490	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KAM345_041510	COG3084	Protein conserved in bacteria
KAM345_041520	COG5001	Diguanylate cyclase
KAM345_041520	COG3706	GGDEF domain
KAM345_041520	COG2203	Gaf domain
KAM345_041520	COG4251	negative regulation of phosphorylation
KAM345_041550	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KAM345_041560	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KAM345_041570	COG1561	YicC-like family, N-terminal region
KAM345_041590	COG1519	Transferase
KAM345_041600	COG0859	PFAM glycosyl transferase family 9
KAM345_041620	COG0463	Glycosyl transferase, family 2
KAM345_041630	COG0859	PFAM glycosyl transferase family 9
KAM345_041640	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KAM345_041650	COG2990	Protein conserved in bacteria
KAM345_041660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KAM345_041680	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KAM345_041690	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KAM345_041700	COG2003	Belongs to the UPF0758 family
KAM345_041710	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KAM345_041720	COG0756	dUTP diphosphatase activity
KAM345_041730	COG1309	transcriptional regulator
KAM345_041740	COG0668	transmembrane transport
KAM345_041760	COG0166	Belongs to the GPI family
KAM345_041770	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KAM345_041780	COG0583	DNA-binding transcription factor activity
KAM345_041800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KAM345_041800	COG1042	CoA-binding domain protein
KAM345_041800	COG0045	succinate-CoA ligase (ADP-forming) activity
KAM345_041810	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
KAM345_041820	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KAM345_041830	COG1739	Uncharacterized protein family UPF0029
KAM345_041840	COG0006	proline dipeptidase activity
KAM345_041850	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KAM345_041860	COG1250	3-hydroxyacyl-CoA dehydrogenase
KAM345_041860	COG1024	Enoyl-CoA hydratase
KAM345_041870	COG0183	Belongs to the thiolase family
KAM345_041920	COG0425	Belongs to the sulfur carrier protein TusA family
KAM345_041930	COG0251	oxidation-reduction process
KAM345_041940	COG2885	chlorophyll binding
KAM345_041970	COG1335	isochorismatase
KAM345_041980	COG2818	Glycosylase
KAM345_041990	COG0752	glycyl-tRNA synthetase alpha subunit
KAM345_042000	COG0751	glycine-tRNA ligase activity
KAM345_042040	COG4251	negative regulation of phosphorylation
KAM345_042040	COG5001	Diguanylate cyclase
KAM345_042040	COG2203	Gaf domain
KAM345_042040	COG3706	GGDEF domain
KAM345_042080	COG0814	amino acid
KAM345_042090	COG0814	amino acid
KAM345_042100	COG3033	Beta-eliminating lyase
KAM345_042110	COG0348	domain, Protein
KAM345_042130	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAM345_042140	COG1773	rubredoxin
KAM345_042140	COG0426	domain, Protein
KAM345_042150	COG3604	Transcriptional regulator
KAM345_042160	COG1609	Transcriptional regulator
KAM345_042240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KAM345_042270	COG2960	long-chain fatty acid transporting porin activity
KAM345_042290	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KAM345_042320	COG3118	belongs to the thioredoxin family
KAM345_042330	COG0513	Belongs to the DEAD box helicase family
KAM345_042340	COG0248	Ppx GppA phosphatase
KAM345_042360	COG0742	ribosomal rna small subunit methyltransferase
KAM345_042400	COG0084	hydrolase, TatD family'
KAM345_042410	COG0805	protein transport
KAM345_042420	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KAM345_042430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KAM345_042440	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KAM345_042450	COG3165	ubiquinone biosynthetic process from chorismate
KAM345_042470	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KAM345_042480	COG0402	S-adenosylhomocysteine deaminase activity
KAM345_042500	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KAM345_042510	COG0848	biopolymer transport protein
KAM345_042520	COG0811	peptide transport
KAM345_042530	COG0811	peptide transport
KAM345_042550	COG2771	luxR family
KAM345_042560	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KAM345_042570	COG1349	DNA-binding transcription factor activity
KAM345_042580	COG0745	RESPONSE REGULATOR receiver
KAM345_042590	COG2205	protein histidine kinase activity
KAM345_042610	COG4452	Inner membrane protein CreD
KAM345_042620	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KAM345_042630	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KAM345_042640	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KAM345_042650	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KAM345_042660	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KAM345_042670	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KAM345_042680	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KAM345_042700	COG0356	it plays a direct role in the translocation of protons across the membrane
KAM345_042720	COG1475	DNA binding
KAM345_042730	COG1192	Involved in chromosome partitioning
KAM345_042740	COG0357	Ribosomal RNA small subunit methyltransferase G
KAM345_042750	COG0445	tRNA wobble uridine modification
KAM345_042760	COG0716	FMN binding
KAM345_042770	COG4774	siderophore transport
KAM345_042780	COG4615	Cyclic peptide transporter
KAM345_042790	COG1120	ATPase activity
KAM345_042800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KAM345_042820	COG3550	peptidyl-serine autophosphorylation
KAM345_042860	COG2801	Transposase and inactivated derivatives
KAM345_042880	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KAM345_042890	COG0706	membrane insertase activity
KAM345_042900	COG0594	ribonuclease P activity
KAM345_042910	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KAM345_042920	COG1126	abc transporter atp-binding protein
KAM345_043010	COG0789	Transcriptional regulator
KAM345_043240	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KAM345_043320	COG0346	lactoylglutathione lyase activity
KAM345_043660	COG3451	type IV secretory pathway VirB4
KAM345_043670	COG5268	conjugation
KAM345_043680	COG3838	Conjugal transfer protein Trbc
KAM345_043690	COG4962	Type ii secretion system protein e
KAM345_043980	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM345_044260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM345_044290	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM345_044300	COG3041	Addiction module toxin RelE StbE family
KAM345_044400	COG2176	DNA-directed DNA polymerase activity
KAM345_044400	COG5002	protein histidine kinase activity
KAM345_044480	COG1192	Involved in chromosome partitioning
KAM345_044550	COG1192	Involved in chromosome partitioning
KAM345_044770	COG3077	Addiction module antitoxin, RelB DinJ family
KAM345_044780	COG2026	Addiction module toxin, RelE StbE family