locus-tag	class	description
KAM471c_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KAM471c_00020	COG0592	DNA-directed DNA polymerase activity
KAM471c_00040	COG0187	DNA topoisomerase II activity
KAM471c_00060	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KAM471c_00070	COG0071	Belongs to the small heat shock protein (HSP20) family
KAM471c_00080	COG0071	Belongs to the small heat shock protein (HSP20) family
KAM471c_00090	COG3977	Valine--pyruvate aminotransferase
KAM471c_00120	COG2814	Major facilitator Superfamily
KAM471c_00130	COG0745	RESPONSE REGULATOR receiver
KAM471c_00140	COG2205	protein histidine kinase activity
KAM471c_00180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KAM471c_00190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM471c_00190	COG4191	Histidine kinase
KAM471c_00210	COG3335	DDE superfamily endonuclease
KAM471c_00220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM471c_00230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM471c_00240	COG1309	transcriptional regulator
KAM471c_00260	COG0561	phosphatase activity
KAM471c_00270	COG2267	carboxylic ester hydrolase activity
KAM471c_00280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KAM471c_00290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KAM471c_00310	COG1758	RNA polymerase activity
KAM471c_00330	COG0859	PFAM glycosyl transferase family 9
KAM471c_00340	COG3642	lipopolysaccharide core region biosynthetic process
KAM471c_00420	COG0589	response to stress
KAM471c_00430	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KAM471c_00440	COG3706	GGDEF domain
KAM471c_00450	COG1528	Iron-storage protein
KAM471c_00460	COG2081	HI0933 family
KAM471c_00470	COG2223	nitrite transmembrane transporter activity
KAM471c_00500	COG1280	lysine exporter protein (LysE YggA)
KAM471c_00530	COG3188	usher protein
KAM471c_00560	COG5433	transposase activity
KAM471c_00570	COG2197	response regulator
KAM471c_00580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM471c_00580	COG2205	protein histidine kinase activity
KAM471c_00600	COG3275	phosphorelay sensor kinase activity
KAM471c_00610	COG3279	Response regulator of the LytR AlgR family
KAM471c_00620	COG2223	nitrite transmembrane transporter activity
KAM471c_00630	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KAM471c_00640	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KAM471c_00680	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KAM471c_00690	COG2166	iron-sulfur cluster assembly
KAM471c_00700	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KAM471c_00740	COG1063	alcohol dehydrogenase
KAM471c_00770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KAM471c_00870	COG1609	Transcriptional regulator
KAM471c_00910	COG1580	Controls the rotational direction of flagella during chemotaxis
KAM471c_00920	COG3161	chorismate lyase activity
KAM471c_00930	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KAM471c_00940	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KAM471c_00980	COG3328	transposase activity
KAM471c_01010	COG2937	Belongs to the GPAT DAPAT family
KAM471c_01020	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KAM471c_01050	COG0534	Mate efflux family protein
KAM471c_01060	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KAM471c_01070	COG2205	protein histidine kinase activity
KAM471c_01080	COG0745	RESPONSE REGULATOR receiver
KAM471c_01100	COG1045	serine acetyltransferase
KAM471c_01120	COG3074	FtsZ-dependent cytokinesis
KAM471c_01130	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
KAM471c_01140	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KAM471c_01140	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KAM471c_01150	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KAM471c_01160	COG1609	Transcriptional regulator
KAM471c_01170	COG3250	beta-galactosidase activity
KAM471c_01180	COG2731	YhcH YjgK YiaL family protein
KAM471c_01190	COG0531	amino acid
KAM471c_01200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM471c_01210	COG0531	amino acid
KAM471c_01220	COG0385	Bile acid
KAM471c_01230	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KAM471c_01280	COG0583	DNA-binding transcription factor activity
KAM471c_01290	COG1079	Belongs to the binding-protein-dependent transport system permease family
KAM471c_01300	COG4603	Belongs to the binding-protein-dependent transport system permease family
KAM471c_01310	COG3845	ABC transporter
KAM471c_01320	COG1744	ABC transporter substrate-binding protein PnrA-like
KAM471c_01350	COG0210	DNA helicase
KAM471c_01410	COG3385	transposase activity
KAM471c_01420	COG1943	Transposase
KAM471c_01430	COG0583	DNA-binding transcription factor activity
KAM471c_01520	COG1280	lysine exporter protein (LysE YggA)
KAM471c_01540	COG2962	Rard protein
KAM471c_01560	COG1012	belongs to the aldehyde dehydrogenase family
KAM471c_01570	COG1396	sequence-specific DNA binding
KAM471c_01580	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KAM471c_01600	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KAM471c_01600	COG0519	Catalyzes the synthesis of GMP from XMP
KAM471c_01620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM471c_01660	COG1322	Protein conserved in bacteria
KAM471c_01670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KAM471c_01680	COG0569	domain protein
KAM471c_01690	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KAM471c_01690	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KAM471c_01700	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KAM471c_01710	COG0242	peptide deformylase activity
KAM471c_01740	COG0758	DNA mediated transformation
KAM471c_01750	COG2922	Belongs to the Smg family
KAM471c_01760	COG0551	DNA topoisomerase type I activity
KAM471c_01770	COG0009	L-threonylcarbamoyladenylate synthase
KAM471c_01780	COG0408	coproporphyrinogen oxidase activity
KAM471c_01790	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KAM471c_01810	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KAM471c_01830	COG3078	GTPase activator activity
KAM471c_01860	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KAM471c_01880	COG3852	Histidine kinase
KAM471c_01900	COG0174	glutamine synthetase
KAM471c_01910	COG1217	gtp-binding protein TYPA
KAM471c_01920	COG1295	ribonuclease BN
KAM471c_01930	COG1490	D-aminoacyl-tRNA deacylase activity
KAM471c_01950	COG0456	acetyltransferase
KAM471c_01970	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KAM471c_01980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KAM471c_01990	COG2610	gluconate transmembrane transporter activity
KAM471c_02000	COG3265	gluconokinase activity
KAM471c_02010	COG0129	dihydroxy-acid dehydratase activity
KAM471c_02020	COG0800	Aldolase
KAM471c_02050	COG1609	Transcriptional regulator
KAM471c_02070	COG4942	peptidase
KAM471c_02080	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KAM471c_02090	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KAM471c_02100	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KAM471c_02110	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KAM471c_02120	COG0316	Belongs to the HesB IscA family
KAM471c_02120	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KAM471c_02130	COG1040	competence protein
KAM471c_02140	COG0596	Alpha beta hydrolase
KAM471c_02170	COG2183	response to ionizing radiation
KAM471c_02180	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KAM471c_02200	COG2205	protein histidine kinase activity
KAM471c_02220	COG0051	transcription antitermination factor activity, RNA binding
KAM471c_02230	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KAM471c_02240	COG0088	Forms part of the polypeptide exit tunnel
KAM471c_02250	COG0089	rRNA binding
KAM471c_02260	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KAM471c_02270	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KAM471c_02280	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KAM471c_02290	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KAM471c_02300	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KAM471c_02310	COG0255	Belongs to the universal ribosomal protein uL29 family
KAM471c_02320	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KAM471c_02330	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KAM471c_02340	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KAM471c_02350	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KAM471c_02360	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KAM471c_02370	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KAM471c_02380	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KAM471c_02390	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KAM471c_02400	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KAM471c_02410	COG1841	ribosomal large subunit assembly
KAM471c_02420	COG0200	Binds to the 23S rRNA
KAM471c_02430	COG0201	protein transport
KAM471c_02440	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KAM471c_02450	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KAM471c_02460	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KAM471c_02470	COG0202	RNA polymerase activity
KAM471c_02480	COG0203	ribosomal protein L17
KAM471c_02540	COG2249	NAD(P)H dehydrogenase (quinone) activity
KAM471c_02550	COG0583	DNA-binding transcription factor activity
KAM471c_02560	COG4221	oxidoreductase activity
KAM471c_02590	COG1770	oligopeptidase
KAM471c_02600	COG2358	TRAP transporter, solute receptor (TAXI family
KAM471c_02630	COG3714	YhhN family
KAM471c_02660	COG0583	DNA-binding transcription factor activity
KAM471c_02680	COG1301	dicarboxylic acid transport
KAM471c_02700	COG2095	MarC family integral membrane protein
KAM471c_02720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KAM471c_02740	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KAM471c_02760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KAM471c_02810	COG0742	ribosomal rna small subunit methyltransferase
KAM471c_02820	COG0552	protein localization to endoplasmic reticulum
KAM471c_02830	COG2884	Cell division ATP-binding protein ftsE
KAM471c_02840	COG2177	Part of the ABC transporter FtsEX involved in
KAM471c_02860	COG0288	reversible hydration of carbon dioxide
KAM471c_02870	COG2188	Transcriptional regulator
KAM471c_02880	COG1228	amidohydrolase
KAM471c_02890	COG0010	Belongs to the arginase family
KAM471c_02900	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KAM471c_02910	COG2986	histidine ammonia-lyase
KAM471c_02920	COG0387	Pfam Sodium calcium exchanger
KAM471c_02930	COG2200	EAL domain
KAM471c_03010	COG3385	transposase activity
KAM471c_03030	COG3267	Type II secretory pathway component ExeA
KAM471c_03030	COG3409	Peptidoglycan-binding domain 1 protein
KAM471c_03050	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KAM471c_03060	COG1459	type II secretion system
KAM471c_03110	COG2165	general secretion pathway protein
KAM471c_03170	COG1077	Cell shape determining protein MreB Mrl
KAM471c_03180	COG1792	Involved in formation and maintenance of cell shape
KAM471c_03190	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KAM471c_03200	COG0424	maF-like protein
KAM471c_03210	COG1530	ribonuclease E activity
KAM471c_03220	COG3164	Protein of unknown function
KAM471c_03240	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KAM471c_03250	COG0312	modulator of DNA gyrase
KAM471c_03280	COG0477	Major facilitator Superfamily
KAM471c_03300	COG2321	neutral zinc metallopeptidase
KAM471c_03320	COG0675	Transposase, IS605 OrfB family
KAM471c_03330	COG0675	Transposase, IS605 OrfB family
KAM471c_03400	COG0189	ligase activity
KAM471c_03410	COG0642	Histidine kinase
KAM471c_03420	COG0745	RESPONSE REGULATOR receiver
KAM471c_03450	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KAM471c_03460	COG0352	thiamine-phosphate diphosphorylase activity
KAM471c_03470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KAM471c_03490	COG2022	thiamine diphosphate biosynthetic process
KAM471c_03500	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KAM471c_03520	COG0110	maltose O-acetyltransferase activity
KAM471c_03550	COG3932	Exopolysaccharide synthesis, ExoD
KAM471c_03590	COG1733	regulation of RNA biosynthetic process
KAM471c_03640	COG2226	methyltransferase
KAM471c_03660	COG1494	fructose-1,6-bisphosphatase
KAM471c_03680	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KAM471c_03690	COG5007	Belongs to the BolA IbaG family
KAM471c_03710	COG2854	intermembrane phospholipid transfer
KAM471c_03720	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KAM471c_03730	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KAM471c_03740	COG1127	ABC transporter
KAM471c_03750	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KAM471c_03750	COG0517	IMP dehydrogenase activity
KAM471c_03760	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KAM471c_03780	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KAM471c_03790	COG1137	ATPase activity
KAM471c_03800	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KAM471c_03820	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM471c_03830	COG1660	Displays ATPase and GTPase activities
KAM471c_03840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM471c_03880	COG3964	amidohydrolase
KAM471c_03940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KAM471c_03950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KAM471c_03970	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KAM471c_03980	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KAM471c_03990	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KAM471c_04000	COG0723	plastoquinol--plastocyanin reductase activity
KAM471c_04010	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KAM471c_04020	COG2857	Cytochrome c1
KAM471c_04030	COG0625	glutathione transferase activity
KAM471c_04040	COG2969	positive regulation of protein catabolic process
KAM471c_04050	COG2823	Periplasmic or secreted lipoprotein
KAM471c_04060	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KAM471c_04070	COG0792	nuclease activity
KAM471c_04080	COG3107	peptidoglycan biosynthetic process
KAM471c_04090	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KAM471c_04100	COG2001	Belongs to the MraZ family
KAM471c_04110	COG0275	rRNA processing
KAM471c_04120	COG3116	cell division
KAM471c_04130	COG0768	penicillin binding
KAM471c_04140	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KAM471c_04150	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KAM471c_04160	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KAM471c_04170	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KAM471c_04180	COG0772	Belongs to the SEDS family
KAM471c_04190	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KAM471c_04200	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KAM471c_04210	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KAM471c_04220	COG0849	cell division
KAM471c_04230	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KAM471c_04240	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KAM471c_04260	COG0653	protein targeting
KAM471c_04280	COG0494	nUDIX hydrolase
KAM471c_04290	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KAM471c_04300	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
KAM471c_04320	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KAM471c_04330	COG1459	type II secretion system
KAM471c_04340	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KAM471c_04350	COG3039	Transposase
KAM471c_04390	COG2186	Transcriptional regulator
KAM471c_04400	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KAM471c_04410	COG0508	dehydrogenase complex catalyzes the overall conversion of
KAM471c_04420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KAM471c_04440	COG0840	transmembrane signaling receptor activity
KAM471c_04450	COG0840	transmembrane signaling receptor activity
KAM471c_04460	COG1752	Esterase of the alpha-beta hydrolase superfamily
KAM471c_04470	COG1049	propionate catabolic process, 2-methylcitrate cycle
KAM471c_04480	COG2200	EAL domain
KAM471c_04500	COG1280	lysine exporter protein (LysE YggA)
KAM471c_04520	COG0523	cobalamin synthesis protein
KAM471c_04530	COG0477	Major facilitator Superfamily
KAM471c_04560	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KAM471c_04570	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KAM471c_04620	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KAM471c_04640	COG3039	Transposase
KAM471c_04670	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KAM471c_04700	COG0732	type I restriction modification DNA specificity domain
KAM471c_04750	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KAM471c_04760	COG3385	transposase activity
KAM471c_04870	COG1546	Belongs to the CinA family
KAM471c_04880	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KAM471c_04890	COG2137	regulation of response to DNA damage stimulus
KAM471c_04900	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KAM471c_04910	COG0527	aspartate kinase activity
KAM471c_04920	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KAM471c_04930	COG1686	Belongs to the peptidase S11 family
KAM471c_04940	COG0586	Pfam SNARE associated Golgi protein
KAM471c_04950	COG1253	flavin adenine dinucleotide binding
KAM471c_04960	COG0525	valine-tRNA ligase activity
KAM471c_04970	COG2927	DNA polymerase III (CHI subunit)
KAM471c_04980	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KAM471c_04990	COG0795	lipopolysaccharide-transporting ATPase activity
KAM471c_05000	COG0795	lipopolysaccharide-transporting ATPase activity
KAM471c_05030	COG0004	ammonium transporteR
KAM471c_05040	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KAM471c_05080	COG2165	general secretion pathway protein
KAM471c_05090	COG0084	hydrolase, TatD family'
KAM471c_05100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KAM471c_05120	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KAM471c_05130	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KAM471c_05140	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KAM471c_05150	COG0813	purine-nucleoside phosphorylase activity
KAM471c_05160	COG3447	MASE1 domain protein
KAM471c_05160	COG5002	protein histidine kinase activity
KAM471c_05160	COG5001	Diguanylate cyclase
KAM471c_05180	COG0560	Phosphoserine phosphatase
KAM471c_05210	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KAM471c_05230	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
KAM471c_05240	COG0776	regulation of translation
KAM471c_05270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KAM471c_05280	COG0735	belongs to the Fur family
KAM471c_05320	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KAM471c_05330	COG0513	Belongs to the DEAD box helicase family
KAM471c_05340	COG3022	response to hydroperoxide
KAM471c_05370	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KAM471c_05380	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KAM471c_05390	COG0762	integral membrane protein
KAM471c_05400	COG1872	DUF167
KAM471c_05440	COG3112	Uncharacterised protein family (UPF0231)
KAM471c_05450	COG3835	regulator
KAM471c_05460	COG2610	gluconate transmembrane transporter activity
KAM471c_05470	COG1929	Belongs to the glycerate kinase type-1 family
KAM471c_05500	COG0583	DNA-binding transcription factor activity
KAM471c_05510	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KAM471c_05540	COG0347	Belongs to the P(II) protein family
KAM471c_05570	COG3842	ATPase activity
KAM471c_05580	COG2837	iron assimilation
KAM471c_05590	COG1438	arginine binding
KAM471c_05600	COG1126	abc transporter atp-binding protein
KAM471c_05610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM471c_05620	COG4215	(ABC) transporter
KAM471c_05630	COG4160	amino acid transport
KAM471c_05640	COG0039	L-malate dehydrogenase activity
KAM471c_05660	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
KAM471c_05670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KAM471c_05670	COG1017	nitric oxide dioxygenase activity
KAM471c_05690	COG4536	flavin adenine dinucleotide binding
KAM471c_05700	COG4137	Cytochrome C assembly protein
KAM471c_05710	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KAM471c_05720	COG0228	four-way junction DNA binding
KAM471c_05730	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KAM471c_05740	COG0336	Belongs to the RNA methyltransferase TrmD family
KAM471c_05750	COG0335	large ribosomal subunit rRNA binding
KAM471c_05780	COG1051	belongs to the nudix hydrolase family
KAM471c_05800	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KAM471c_05810	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KAM471c_05820	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KAM471c_05840	COG0583	DNA-binding transcription factor activity
KAM471c_05850	COG0640	Transcriptional regulator
KAM471c_05860	COG0268	Binds directly to 16S ribosomal RNA
KAM471c_05870	COG0728	peptidoglycan biosynthetic process
KAM471c_05880	COG0196	riboflavin kinase activity
KAM471c_05890	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KAM471c_05900	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KAM471c_05910	COG1047	Peptidyl-prolyl cis-trans
KAM471c_05920	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KAM471c_06020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KAM471c_06020	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KAM471c_06050	COG1854	S-ribosylhomocysteine lyase activity
KAM471c_06060	COG3706	GGDEF domain
KAM471c_06070	COG0557	exoribonuclease II activity
KAM471c_06080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KAM471c_06100	COG2153	protein acetylation
KAM471c_06120	COG1914	H( )-stimulated, divalent metal cation uptake system
KAM471c_06130	COG0360	Binds together with S18 to 16S ribosomal RNA
KAM471c_06140	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KAM471c_06150	COG0359	binds to the 23S rRNA
KAM471c_06230	COG1238	metal cluster binding
KAM471c_06240	COG0612	Peptidase, M16
KAM471c_06250	COG2918	glutathione biosynthetic process
KAM471c_06260	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KAM471c_06270	COG1027	Aspartate ammonia-lyase
KAM471c_06280	COG3030	protein affecting phage T7 exclusion by the F plasmid
KAM471c_06290	COG0534	Mate efflux family protein
KAM471c_06310	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KAM471c_06320	COG0459	protein refolding
KAM471c_06360	COG0564	pseudouridine synthase activity
KAM471c_06370	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KAM471c_06380	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KAM471c_06400	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KAM471c_06410	COG4208	sulfate ABC transporter
KAM471c_06420	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KAM471c_06430	COG0583	DNA-binding transcription factor activity
KAM471c_06440	COG3397	chitin binding
KAM471c_06450	COG0840	transmembrane signaling receptor activity
KAM471c_06500	COG1328	CTP reductase activity
KAM471c_06510	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KAM471c_06540	COG1448	Aminotransferase
KAM471c_06550	COG2194	sulfuric ester hydrolase activity
KAM471c_06600	COG1215	transferase activity, transferring glycosyl groups
KAM471c_06620	COG3118	belongs to the thioredoxin family
KAM471c_06620	COG0457	Tetratricopeptide repeat
KAM471c_06690	COG0513	Belongs to the DEAD box helicase family
KAM471c_06700	COG0840	transmembrane signaling receptor activity
KAM471c_06720	COG4166	transmembrane transport
KAM471c_06750	COG1024	Enoyl-CoA hydratase
KAM471c_06780	COG4221	oxidoreductase activity
KAM471c_06790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KAM471c_06800	COG0442	prolyl-tRNA aminoacylation
KAM471c_06810	COG0840	transmembrane signaling receptor activity
KAM471c_06820	COG0632	four-way junction helicase activity
KAM471c_06830	COG2255	four-way junction helicase activity
KAM471c_06840	COG1271	oxidase subunit
KAM471c_06850	COG1294	oxidase, subunit
KAM471c_06860	COG3790	cyd operon protein YbgE
KAM471c_06870	COG0824	Thioesterase
KAM471c_06880	COG0811	peptide transport
KAM471c_06910	COG0823	Involved in the tonB-independent uptake of proteins
KAM471c_06920	COG2885	chlorophyll binding
KAM471c_06930	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
KAM471c_06940	COG0840	transmembrane signaling receptor activity
KAM471c_06950	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KAM471c_06970	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KAM471c_06980	COG1640	4-alpha-glucanotransferase
KAM471c_06990	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KAM471c_07050	COG2130	NADP-dependent
KAM471c_07060	COG1846	Transcriptional regulator
KAM471c_07120	COG0561	phosphatase activity
KAM471c_07150	COG0733	neurotransmitter:sodium symporter activity
KAM471c_07160	COG0733	neurotransmitter:sodium symporter activity
KAM471c_07190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KAM471c_07220	COG1794	racemase activity, acting on amino acids and derivatives
KAM471c_07240	COG1022	Amp-dependent synthetase and ligase
KAM471c_07260	COG0456	acetyltransferase
KAM471c_07290	COG2425	protein containing a von Willebrand factor type A (vWA) domain
KAM471c_07300	COG5001	Diguanylate cyclase
KAM471c_07300	COG5002	protein histidine kinase activity
KAM471c_07320	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KAM471c_07340	COG0456	acetyltransferase
KAM471c_07360	COG0456	acetyltransferase
KAM471c_07370	COG1902	pentaerythritol trinitrate reductase activity
KAM471c_07390	COG2852	Protein conserved in bacteria
KAM471c_07410	COG2957	Belongs to the agmatine deiminase family
KAM471c_07420	COG0154	amidase activity
KAM471c_07510	COG1917	Cupin 2, conserved barrel domain protein
KAM471c_07510	COG2207	Transcriptional regulator
KAM471c_07530	COG0513	Belongs to the DEAD box helicase family
KAM471c_07540	COG2199	diguanylate cyclase activity
KAM471c_07540	COG2203	Gaf domain
KAM471c_07620	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
KAM471c_07640	COG0577	efflux transmembrane transporter activity
KAM471c_07640	COG1136	(ABC) transporter
KAM471c_07650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM471c_07660	COG0745	RESPONSE REGULATOR receiver
KAM471c_07680	COG2205	protein histidine kinase activity
KAM471c_07740	COG1280	lysine exporter protein (LysE YggA)
KAM471c_07750	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KAM471c_07760	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KAM471c_07780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM471c_07840	COG0745	RESPONSE REGULATOR receiver
KAM471c_07850	COG3104	oligopeptide transport
KAM471c_07860	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KAM471c_07870	COG1555	photosystem II stabilization
KAM471c_07890	COG2350	Protein conserved in bacteria
KAM471c_07900	COG2917	probably involved in intracellular septation
KAM471c_07910	COG0076	glutamate decarboxylase activity
KAM471c_07920	COG1272	protein, Hemolysin III
KAM471c_07930	COG0569	domain protein
KAM471c_07930	COG2985	domain, Protein
KAM471c_07950	COG0477	Major facilitator Superfamily
KAM471c_07960	COG0583	DNA-binding transcription factor activity
KAM471c_07970	COG3227	Zinc metalloprotease (Elastase)
KAM471c_07980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KAM471c_07990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KAM471c_08010	COG2731	YhcH YjgK YiaL family protein
KAM471c_08030	COG0668	transmembrane transport
KAM471c_08050	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KAM471c_08070	COG0789	Transcriptional regulator
KAM471c_08190	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KAM471c_08210	COG0488	(ABC) transporter
KAM471c_08220	COG0517	IMP dehydrogenase activity
KAM471c_08220	COG0516	GMP reductase activity
KAM471c_08240	COG0784	Response regulator, receiver
KAM471c_08240	COG0835	chemotaxis
KAM471c_08250	COG2755	lipolytic protein G-D-S-L family
KAM471c_08260	COG4181	ATPase activity
KAM471c_08270	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KAM471c_08280	COG1090	epimerase
KAM471c_08290	COG2200	EAL domain
KAM471c_08300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KAM471c_08310	COG4935	Belongs to the peptidase S8 family
KAM471c_08310	COG2234	aminopeptidase activity
KAM471c_08320	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KAM471c_08330	COG3171	Protein conserved in bacteria
KAM471c_08340	COG2066	Belongs to the glutaminase family
KAM471c_08350	COG2897	thiosulfate sulfurtransferase activity
KAM471c_08370	COG1132	(ABC) transporter
KAM471c_08390	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
KAM471c_08400	COG3300	MHYT domain
KAM471c_08400	COG5001	Diguanylate cyclase
KAM471c_08440	COG4628	conserved protein (DUF2132)
KAM471c_08450	COG0688	phosphatidylethanolamine metabolic process
KAM471c_08460	COG1162	GTPase activity
KAM471c_08470	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KAM471c_08480	COG1278	Cold shock
KAM471c_08500	COG0840	transmembrane signaling receptor activity
KAM471c_08510	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KAM471c_08570	COG0848	biopolymer transport protein
KAM471c_08580	COG0811	peptide transport
KAM471c_08590	COG0811	peptide transport
KAM471c_08610	COG4206	TonB-dependent receptor
KAM471c_08620	COG4174	ABC transporter (Permease)
KAM471c_08630	COG4239	(ABC) transporter, permease
KAM471c_08650	COG0444	Belongs to the ABC transporter superfamily
KAM471c_08660	COG4608	Belongs to the ABC transporter superfamily
KAM471c_08680	COG2195	Cleaves the N-terminal amino acid of tripeptides
KAM471c_08690	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
KAM471c_08700	COG1073	alpha beta
KAM471c_08730	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KAM471c_08780	COG0243	molybdopterin cofactor binding
KAM471c_08790	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KAM471c_08790	COG1648	precorrin-2 dehydrogenase activity
KAM471c_08840	COG1116	anion transmembrane transporter activity
KAM471c_08840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KAM471c_08850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KAM471c_08860	COG1116	anion transmembrane transporter activity
KAM471c_08870	COG2146	nitrite reductase [NAD(P)H] activity
KAM471c_08870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KAM471c_08880	COG2146	nitrite reductase [NAD(P)H] activity
KAM471c_08880	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KAM471c_08890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM471c_08900	COG2313	pseudouridylate synthase activity
KAM471c_08940	COG0521	Mo-molybdopterin cofactor biosynthetic process
KAM471c_08960	COG2966	Psort location CytoplasmicMembrane, score
KAM471c_08970	COG3610	response to peptide
KAM471c_08990	COG4175	Glycine betaine
KAM471c_09000	COG4176	ABC-type proline glycine betaine transport system permease component
KAM471c_09010	COG2113	Glycine betaine
KAM471c_09020	COG0175	sulfate reduction
KAM471c_09030	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KAM471c_09040	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KAM471c_09060	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KAM471c_09070	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KAM471c_09090	COG0786	glutamate:sodium symporter activity
KAM471c_09100	COG0252	asparaginase activity
KAM471c_09110	COG3139	Protein of unknown function (DUF1315)
KAM471c_09150	COG0616	signal peptide processing
KAM471c_09160	COG1902	pentaerythritol trinitrate reductase activity
KAM471c_09160	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAM471c_09170	COG0778	Nitroreductase
KAM471c_09190	COG0110	maltose O-acetyltransferase activity
KAM471c_09200	COG2264	protein methyltransferase activity
KAM471c_09210	COG0604	alcohol dehydrogenase
KAM471c_09220	COG0583	DNA-binding transcription factor activity
KAM471c_09230	COG1263	PTS System
KAM471c_09230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM471c_09230	COG2190	(PTS) system
KAM471c_09240	COG4145	pantothenate transmembrane transporter activity
KAM471c_09250	COG3924	membrane
KAM471c_09260	COG0439	Biotin carboxylase
KAM471c_09270	COG0511	ligase activity, forming carbon-carbon bonds
KAM471c_09280	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KAM471c_09290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KAM471c_09330	COG3381	protein complex oligomerization
KAM471c_09350	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KAM471c_09370	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KAM471c_09380	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KAM471c_09380	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KAM471c_09410	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KAM471c_09420	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KAM471c_09430	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KAM471c_09440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KAM471c_09450	COG4172	Belongs to the ABC transporter superfamily
KAM471c_09470	COG0601	transmembrane transport
KAM471c_09480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAM471c_09490	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KAM471c_09500	COG0142	geranyltranstransferase activity
KAM471c_09510	COG1722	exodeoxyribonuclease VII activity
KAM471c_09520	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KAM471c_09530	COG1360	Flagellar Motor Protein
KAM471c_09560	COG1534	Rna-binding protein
KAM471c_09570	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KAM471c_09590	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KAM471c_09600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KAM471c_09610	COG0149	triose-phosphate isomerase activity
KAM471c_09620	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KAM471c_09630	COG0779	Required for maturation of 30S ribosomal subunits
KAM471c_09640	COG0195	Participates in both transcription termination and antitermination
KAM471c_09650	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KAM471c_09660	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KAM471c_09670	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KAM471c_09680	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KAM471c_09690	COG1185	polyribonucleotide nucleotidyltransferase activity
KAM471c_09700	COG2211	Major facilitator Superfamily
KAM471c_09710	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KAM471c_09720	COG1422	Protein of unknown function (DUF1090)
KAM471c_09730	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KAM471c_09740	COG0826	peptidase U32
KAM471c_09780	COG0312	modulator of DNA gyrase
KAM471c_09790	COG0312	modulator of DNA gyrase
KAM471c_09810	COG4974	Belongs to the 'phage' integrase family
KAM471c_09820	COG1970	mechanosensitive ion channel activity
KAM471c_09850	COG0789	Transcriptional regulator
KAM471c_09880	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM471c_09900	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KAM471c_09910	COG0321	lipoyl(octanoyl) transferase activity
KAM471c_09920	COG2921	Belongs to the UPF0250 family
KAM471c_09930	COG1686	Belongs to the peptidase S11 family
KAM471c_09940	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KAM471c_09950	COG2951	lytic endotransglycosylase activity
KAM471c_09960	COG0772	Belongs to the SEDS family
KAM471c_09970	COG0768	penicillin binding
KAM471c_09980	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KAM471c_09990	COG0799	negative regulation of ribosome biogenesis
KAM471c_10000	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KAM471c_10040	COG0495	leucyl-tRNA aminoacylation
KAM471c_10050	COG2888	peptidyl-tyrosine sulfation
KAM471c_10060	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KAM471c_10070	COG4535	Mg2 and Co2 transporter CorC
KAM471c_10080	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KAM471c_10090	COG1702	phosphate starvation-inducible protein PhoH
KAM471c_10100	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KAM471c_10110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KAM471c_10120	COG1335	isochorismatase
KAM471c_10130	COG1278	Cold shock
KAM471c_10160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAM471c_10170	COG2199	diguanylate cyclase activity
KAM471c_10190	COG2199	diguanylate cyclase activity
KAM471c_10210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KAM471c_10240	COG1464	Belongs to the NlpA lipoprotein family
KAM471c_10250	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KAM471c_10260	COG2011	ABC-type metal ion transport system permease component
KAM471c_10270	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KAM471c_10290	COG0516	GMP reductase activity
KAM471c_10300	COG0189	ligase activity
KAM471c_10300	COG4067	protein conserved in archaea
KAM471c_10350	COG0300	oxidoreductase activity
KAM471c_10390	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KAM471c_10400	COG3214	Protein conserved in bacteria
KAM471c_10430	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
KAM471c_10440	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
KAM471c_10450	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KAM471c_10460	COG1053	succinate dehydrogenase
KAM471c_10480	COG0584	glycerophosphoryl diester phosphodiesterase
KAM471c_10490	COG1511	domain protein
KAM471c_10490	COG3264	Mechanosensitive ion channel
KAM471c_10510	COG0739	heme binding
KAM471c_10540	COG0583	DNA-binding transcription factor activity
KAM471c_10570	COG0583	DNA-binding transcription factor activity
KAM471c_10580	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KAM471c_10660	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KAM471c_10670	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KAM471c_10690	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KAM471c_10700	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KAM471c_10710	COG0546	phosphoglycolate phosphatase activity
KAM471c_10720	COG0180	Tryptophanyl-tRNA synthetase
KAM471c_10750	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KAM471c_10770	COG1012	belongs to the aldehyde dehydrogenase family
KAM471c_10800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAM471c_10830	COG0657	acetylesterase activity
KAM471c_10850	COG0471	metal ion transport
KAM471c_10850	COG0490	domain, Protein
KAM471c_10860	COG0012	GTP binding
KAM471c_10870	COG0193	aminoacyl-tRNA hydrolase activity
KAM471c_10880	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KAM471c_10890	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KAM471c_10900	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KAM471c_10910	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KAM471c_10920	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KAM471c_10930	COG2890	protein-(glutamine-N5) methyltransferase activity
KAM471c_10950	COG2912	Transglutaminase-like superfamily
KAM471c_10960	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KAM471c_10970	COG1301	dicarboxylic acid transport
KAM471c_10990	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KAM471c_11020	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KAM471c_11030	COG1115	amino acid carrier protein
KAM471c_11070	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KAM471c_11090	COG0189	ligase activity
KAM471c_11100	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KAM471c_11120	COG3091	SprT-like family
KAM471c_11140	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KAM471c_11160	COG2801	Transposase and inactivated derivatives
KAM471c_11200	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KAM471c_11210	COG0739	heme binding
KAM471c_11220	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KAM471c_11230	COG3408	Glycogen debranching enzyme
KAM471c_11230	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
KAM471c_11250	COG1881	PFAM PEBP family protein
KAM471c_11260	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KAM471c_11270	COG0583	DNA-binding transcription factor activity
KAM471c_11290	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KAM471c_11310	COG0583	DNA-binding transcription factor activity
KAM471c_11320	COG1028	Short-chain dehydrogenase reductase Sdr
KAM471c_11330	COG0616	signal peptide processing
KAM471c_11340	COG3724	N-succinylarginine dihydrolase activity
KAM471c_11380	COG0840	transmembrane signaling receptor activity
KAM471c_11400	COG2971	BadF BadG BcrA BcrD
KAM471c_11430	COG4608	Belongs to the ABC transporter superfamily
KAM471c_11440	COG0444	Belongs to the ABC transporter superfamily
KAM471c_11450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAM471c_11480	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KAM471c_11510	COG0640	Transcriptional regulator
KAM471c_11520	COG0798	PFAM Bile acid sodium symporter
KAM471c_11530	COG1393	Belongs to the ArsC family
KAM471c_11560	COG1677	Flagellar hook-basal body complex protein FliE
KAM471c_11580	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KAM471c_11690	COG1684	flagellar biosynthetic protein fliR
KAM471c_11710	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KAM471c_11730	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KAM471c_11780	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KAM471c_11790	COG2198	Histidine kinase
KAM471c_11790	COG0784	Response regulator, receiver
KAM471c_11790	COG0643	Histidine kinase
KAM471c_11810	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KAM471c_11820	COG1360	Flagellar Motor Protein
KAM471c_11830	COG1192	Involved in chromosome partitioning
KAM471c_11850	COG0835	chemotaxis
KAM471c_11880	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KAM471c_11890	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KAM471c_11900	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KAM471c_11910	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KAM471c_11920	COG1138	Cytochrome C-type biogenesis protein
KAM471c_11930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KAM471c_11950	COG0457	Tetratricopeptide repeat
KAM471c_11980	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KAM471c_11990	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KAM471c_11990	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KAM471c_12020	COG0259	pyridoxamine-phosphate oxidase activity
KAM471c_12080	COG3153	acetyltransferase
KAM471c_12110	COG0800	Aldolase
KAM471c_12120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM471c_12140	COG2721	sulfolactate sulfo-lyase activity
KAM471c_12150	COG0246	Mannitol dehydrogenase
KAM471c_12230	COG3039	Transposase
KAM471c_12290	COG1484	DNA-dependent DNA replication
KAM471c_12300	COG4584	PFAM Integrase catalytic
KAM471c_12360	COG2916	Histone family protein nucleoid-structuring protein H-NS
KAM471c_12410	COG3385	transposase activity
KAM471c_12470	COG0210	DNA helicase
KAM471c_12490	COG3328	transposase activity
KAM471c_12510	COG3328	transposase activity
KAM471c_12570	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KAM471c_12580	COG2867	negative regulation of translational initiation
KAM471c_12590	COG2914	Belongs to the UPF0125 (RnfH) family
KAM471c_12600	COG0702	epimerase
KAM471c_12610	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAM471c_12620	COG1454	alcohol dehydrogenase
KAM471c_12650	COG1957	nucleoside hydrolase
KAM471c_12710	COG1280	lysine exporter protein (LysE YggA)
KAM471c_12730	COG3263	regulation of cellular component size
KAM471c_12750	COG1876	peptidase activity
KAM471c_12760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KAM471c_12770	COG1393	Belongs to the ArsC family
KAM471c_12790	COG3069	C4-dicarboxylate transmembrane transporter activity
KAM471c_12800	COG1473	amidohydrolase
KAM471c_12820	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KAM471c_12830	COG0017	Asparaginyl-tRNA synthetase
KAM471c_12870	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KAM471c_12880	COG0156	8-amino-7-oxononanoate synthase activity
KAM471c_12890	COG2226	methyltransferase
KAM471c_12890	COG1073	alpha beta
KAM471c_12900	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KAM471c_12910	COG0501	Belongs to the peptidase M48B family
KAM471c_12920	COG3217	Mosc domain protein beta barrel domain protein
KAM471c_12920	COG3217	Mosc domain protein beta barrel domain protein
KAM471c_12920	COG0633	Ferredoxin
KAM471c_12920	COG0633	Ferredoxin
KAM471c_12940	COG0674	pyruvate-flavodoxin oxidoreductase activity
KAM471c_12940	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KAM471c_12940	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KAM471c_12940	COG1013	pyruvate-flavodoxin oxidoreductase activity
KAM471c_12950	COG2841	Protein conserved in bacteria
KAM471c_12970	COG0534	Mate efflux family protein
KAM471c_13020	COG1454	alcohol dehydrogenase
KAM471c_13050	COG1309	transcriptional regulator
KAM471c_13080	COG0791	NLP P60 protein
KAM471c_13090	COG0583	DNA-binding transcription factor activity
KAM471c_13130	COG0500	methyltransferase
KAM471c_13140	COG4106	trans-aconitate 2-methyltransferase activity
KAM471c_13150	COG1801	Protein of unknown function DUF72
KAM471c_13160	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KAM471c_13170	COG0217	transcriptional regulatory protein
KAM471c_13180	COG2194	sulfuric ester hydrolase activity
KAM471c_13190	COG1846	Transcriptional regulator
KAM471c_13190	COG1940	carbohydrate kinase activity
KAM471c_13200	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KAM471c_13210	COG0363	glucosamine-6-phosphate deaminase activity
KAM471c_13220	COG2190	(PTS) system
KAM471c_13220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM471c_13220	COG1263	PTS System
KAM471c_13240	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KAM471c_13250	COG0735	belongs to the Fur family
KAM471c_13270	COG0716	FMN binding
KAM471c_13300	COG0596	Alpha beta hydrolase
KAM471c_13310	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
KAM471c_13320	COG0033	Phosphoglucomutase
KAM471c_13340	COG1846	Transcriptional regulator
KAM471c_13350	COG2951	lytic endotransglycosylase activity
KAM471c_13360	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KAM471c_13370	COG4136	ATPase activity
KAM471c_13390	COG4134	Bacterial extracellular solute-binding protein
KAM471c_13400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KAM471c_13410	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KAM471c_13430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KAM471c_13450	COG0729	surface antigen
KAM471c_13460	COG2911	Protein conserved in bacteria
KAM471c_13480	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KAM471c_13510	COG0741	lytic transglycosylase activity
KAM471c_13540	COG1607	acyl-coa hydrolase
KAM471c_13570	COG0741	lytic transglycosylase activity
KAM471c_13570	COG1388	LysM domain
KAM471c_13580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KAM471c_13590	COG2226	methyltransferase
KAM471c_13600	COG0328	RNA-DNA hybrid ribonuclease activity
KAM471c_13610	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KAM471c_13630	COG0784	Response regulator, receiver
KAM471c_13630	COG3437	response regulator, receiver
KAM471c_13650	COG0784	Response regulator, receiver
KAM471c_13650	COG3437	response regulator, receiver
KAM471c_13660	COG1960	acyl-CoA dehydrogenase activity
KAM471c_13670	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KAM471c_13680	COG0121	glutamine amidotransferase
KAM471c_13700	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KAM471c_13750	COG2197	response regulator
KAM471c_13760	COG3850	Histidine kinase
KAM471c_13770	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KAM471c_13780	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KAM471c_13780	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
KAM471c_13800	COG0243	molybdopterin cofactor binding
KAM471c_13810	COG0437	4 iron, 4 sulfur cluster binding
KAM471c_13820	COG0348	domain, Protein
KAM471c_13840	COG3005	denitrification pathway
KAM471c_13850	COG0521	Mo-molybdopterin cofactor biosynthetic process
KAM471c_13860	COG0315	cyclic pyranopterin monophosphate synthase activity
KAM471c_13870	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KAM471c_13880	COG0314	molybdopterin synthase activity
KAM471c_13910	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KAM471c_13920	COG2267	carboxylic ester hydrolase activity
KAM471c_13930	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KAM471c_13950	COG0302	gtp cyclohydrolase
KAM471c_13960	COG0840	transmembrane signaling receptor activity
KAM471c_13970	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KAM471c_13990	COG0583	DNA-binding transcription factor activity
KAM471c_14020	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KAM471c_14050	COG2195	Cleaves the N-terminal amino acid of tripeptides
KAM471c_14060	COG1166	arginine decarboxylase activity
KAM471c_14140	COG1061	Type III restriction enzyme res subunit
KAM471c_14170	COG0675	Transposase, IS605 OrfB family
KAM471c_14190	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KAM471c_14200	COG1187	pseudouridine synthase activity
KAM471c_14210	COG2807	transmembrane transport
KAM471c_14230	COG0583	DNA-binding transcription factor activity
KAM471c_14260	COG1607	acyl-coa hydrolase
KAM471c_14270	COG2979	Protein of unknown function (DUF533)
KAM471c_14290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KAM471c_14310	COG1294	oxidase, subunit
KAM471c_14320	COG2814	Major facilitator Superfamily
KAM471c_14330	COG0656	L-ascorbic acid biosynthetic process
KAM471c_14370	COG0583	DNA-binding transcription factor activity
KAM471c_14380	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KAM471c_14390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KAM471c_14400	COG2271	Major facilitator Superfamily
KAM471c_14420	COG2271	Major facilitator Superfamily
KAM471c_14430	COG1349	DNA-binding transcription factor activity
KAM471c_14460	COG0584	glycerophosphoryl diester phosphodiesterase
KAM471c_14470	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAM471c_14480	COG0287	Prephenate dehydrogenase
KAM471c_14480	COG1605	Chorismate mutase
KAM471c_14500	COG3085	chromosome segregation
KAM471c_14510	COG4574	serine-type endopeptidase inhibitor activity
KAM471c_14540	COG0675	Transposase, IS605 OrfB family
KAM471c_14560	COG4771	TonB-dependent receptor
KAM471c_14570	COG3083	sulfuric ester hydrolase activity
KAM471c_14580	COG3082	Protein of unknown function (DUF1414)
KAM471c_14590	COG3081	Nucleoid-associated protein
KAM471c_14610	COG1175	transmembrane transport
KAM471c_14620	COG3833	ABC-type maltose transport systems, permease component
KAM471c_14630	COG3842	ATPase activity
KAM471c_14650	COG0596	Alpha beta hydrolase
KAM471c_14680	COG4783	chaperone-mediated protein folding
KAM471c_14700	COG1393	Belongs to the ArsC family
KAM471c_14740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM471c_14750	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KAM471c_14760	COG2431	L-lysine efflux transmembrane transporter activity
KAM471c_14780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM471c_14800	COG4160	amino acid transport
KAM471c_14820	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KAM471c_14840	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAM471c_14850	COG2373	Large extracellular alpha-helical protein
KAM471c_14860	COG4953	penicillin-binding protein 1C
KAM471c_14880	COG0301	tRNA thio-modification
KAM471c_14880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KAM471c_14910	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KAM471c_14990	COG2089	acid synthase
KAM471c_15010	COG1083	cytidylyl-transferase
KAM471c_15050	COG0318	PFAM AMP-dependent synthetase and ligase
KAM471c_15080	COG1216	Glycosyl transferase, family 2
KAM471c_15180	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KAM471c_15200	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KAM471c_15210	COG1086	Polysaccharide biosynthesis protein
KAM471c_15220	COG2801	Transposase and inactivated derivatives
KAM471c_15230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KAM471c_15250	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KAM471c_15280	COG0675	Transposase, IS605 OrfB family
KAM471c_15290	COG4584	PFAM Integrase catalytic
KAM471c_15300	COG1484	DNA-dependent DNA replication
KAM471c_15320	COG0346	lactoylglutathione lyase activity
KAM471c_15330	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KAM471c_15340	COG4660	Part of a membrane complex involved in electron transport
KAM471c_15350	COG4659	FMN binding
KAM471c_15360	COG4658	electron transport chain
KAM471c_15380	COG2878	Part of a membrane complex involved in electron transport
KAM471c_15390	COG4657	Part of a membrane complex involved in electron transport
KAM471c_15400	COG0675	Transposase, IS605 OrfB family
KAM471c_15420	COG0697	spore germination
KAM471c_15460	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KAM471c_15470	COG1288	antiporter activity
KAM471c_15480	COG0436	Aminotransferase
KAM471c_15500	COG3385	transposase activity
KAM471c_15510	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KAM471c_15520	COG2027	D-alanyl-D-alanine carboxypeptidase
KAM471c_15530	COG1061	Type III restriction enzyme res subunit
KAM471c_15540	COG1566	PFAM secretion protein HlyD family protein
KAM471c_15570	COG0675	Transposase, IS605 OrfB family
KAM471c_15580	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KAM471c_15580	COG3264	Mechanosensitive ion channel
KAM471c_15590	COG1966	Carbon starvation protein
KAM471c_15600	COG3279	Response regulator of the LytR AlgR family
KAM471c_15610	COG3275	phosphorelay sensor kinase activity
KAM471c_15630	COG1012	belongs to the aldehyde dehydrogenase family
KAM471c_15630	COG1454	alcohol dehydrogenase
KAM471c_15640	COG2095	MarC family integral membrane protein
KAM471c_15660	COG0601	transmembrane transport
KAM471c_15670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAM471c_15680	COG0444	Belongs to the ABC transporter superfamily
KAM471c_15700	COG0861	Integral membrane protein TerC family
KAM471c_15710	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KAM471c_15730	COG1301	dicarboxylic acid transport
KAM471c_15760	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KAM471c_15790	COG0537	adenosine 5'-monophosphoramidase activity
KAM471c_15860	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAM471c_15870	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAM471c_15900	COG2354	Protein conserved in bacteria
KAM471c_15920	COG1164	Oligoendopeptidase f
KAM471c_15930	COG1164	Oligoendopeptidase f
KAM471c_15940	COG3150	esterase
KAM471c_15950	COG1252	NADH dehydrogenase
KAM471c_15960	COG0393	Putative heavy-metal-binding
KAM471c_15970	COG1368	sulfuric ester hydrolase activity
KAM471c_15990	COG0527	aspartate kinase activity
KAM471c_16000	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KAM471c_16000	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KAM471c_16010	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KAM471c_16060	COG0583	DNA-binding transcription factor activity
KAM471c_16070	COG1620	l-lactate permease
KAM471c_16080	COG0247	lactate metabolic process
KAM471c_16090	COG1139	Iron-sulfur cluster binding protein
KAM471c_16170	COG0577	efflux transmembrane transporter activity
KAM471c_16180	COG1136	(ABC) transporter
KAM471c_16220	COG2814	Major facilitator Superfamily
KAM471c_16280	COG0672	)-iron permease
KAM471c_16350	COG2308	Evidence 4 Homologs of previously reported genes of
KAM471c_16400	COG0659	secondary active sulfate transmembrane transporter activity
KAM471c_16440	COG3039	Transposase
KAM471c_16450	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KAM471c_16470	COG0326	Molecular chaperone. Has ATPase activity
KAM471c_16480	COG0563	adenylate kinase activity
KAM471c_16490	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KAM471c_16500	COG3788	relative of glutathione S-transferase, MAPEG superfamily
KAM471c_16510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM471c_16520	COG0840	transmembrane signaling receptor activity
KAM471c_16550	COG5001	Diguanylate cyclase
KAM471c_16550	COG3300	MHYT domain
KAM471c_16600	COG1021	2,3-dihydroxybenzoate-AMP ligase
KAM471c_16610	COG1535	isochorismatase
KAM471c_16610	COG3433	isochorismatase activity
KAM471c_16620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KAM471c_16630	COG1028	Short-chain dehydrogenase reductase Sdr
KAM471c_16650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KAM471c_16660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KAM471c_16670	COG2977	Belongs to the P-Pant transferase superfamily
KAM471c_16680	COG1120	ATPase activity
KAM471c_16690	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAM471c_16700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAM471c_16710	COG4771	TonB-dependent receptor
KAM471c_16790	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KAM471c_16800	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KAM471c_16810	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAM471c_16820	COG0861	Integral membrane protein TerC family
KAM471c_16850	COG1022	Amp-dependent synthetase and ligase
KAM471c_16860	COG0295	cytidine deaminase activity
KAM471c_16870	COG1346	cytolysis
KAM471c_16880	COG1380	Effector of murein hydrolase LrgA
KAM471c_16890	COG3345	alpha-galactosidase
KAM471c_16910	COG2925	Exonuclease
KAM471c_16920	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KAM471c_16940	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KAM471c_16940	COG0392	lysyltransferase activity
KAM471c_16970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KAM471c_16980	COG0436	Aminotransferase
KAM471c_16990	COG0583	DNA-binding transcription factor activity
KAM471c_17000	COG2160	L-arabinose isomerase activity
KAM471c_17020	COG1069	ribulokinase activity
KAM471c_17030	COG1879	ABC-type sugar transport system periplasmic component
KAM471c_17040	COG1129	ABC transporter
KAM471c_17050	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAM471c_17070	COG0254	rRNA binding
KAM471c_17100	COG1451	nucleotide metabolic process
KAM471c_17130	COG3069	C4-dicarboxylate transmembrane transporter activity
KAM471c_17150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAM471c_17150	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KAM471c_17160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KAM471c_17200	COG2009	succinate dehydrogenase
KAM471c_17210	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KAM471c_17240	COG0567	Dehydrogenase, E1 component
KAM471c_17250	COG0508	dehydrogenase complex catalyzes the overall conversion of
KAM471c_17260	COG0045	succinate-CoA ligase (ADP-forming) activity
KAM471c_17270	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KAM471c_17280	COG2801	Transposase and inactivated derivatives
KAM471c_17310	COG2983	Belongs to the UPF0260 family
KAM471c_17320	COG4584	PFAM Integrase catalytic
KAM471c_17330	COG1484	DNA-dependent DNA replication
KAM471c_17340	COG1882	Formate acetyltransferase
KAM471c_17350	COG2116	formate transmembrane transporter activity
KAM471c_17360	COG1944	ATP diphosphatase activity
KAM471c_17380	COG2076	Multidrug Resistance protein
KAM471c_17390	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KAM471c_17400	COG1278	Cold shock
KAM471c_17410	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KAM471c_17420	COG0542	response to heat
KAM471c_17430	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KAM471c_17440	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KAM471c_17450	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KAM471c_17460	COG3134	Outer membrane lipoprotein
KAM471c_17470	COG3706	GGDEF domain
KAM471c_17480	COG0492	ferredoxin-NADP+ reductase activity
KAM471c_17510	COG0686	Belongs to the AlaDH PNT family
KAM471c_17530	COG1674	ftsk spoiiie
KAM471c_17530	COG0531	amino acid
KAM471c_17540	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KAM471c_17550	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KAM471c_17560	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KAM471c_17570	COG1286	toxin biosynthetic process
KAM471c_17580	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KAM471c_17590	COG2723	6-phospho-beta-galactosidase activity
KAM471c_17600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM471c_17600	COG1263	PTS System
KAM471c_17610	COG1609	Transcriptional regulator
KAM471c_17630	COG4172	Belongs to the ABC transporter superfamily
KAM471c_17650	COG4171	peptide transport system, permease
KAM471c_17690	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KAM471c_17700	COG1842	Phage shock protein A
KAM471c_17730	COG3106	COG3106 Predicted ATPase
KAM471c_17740	COG3768	UPF0283 membrane protein
KAM471c_17760	COG2154	pterin-4-alpha-carbinolamine dehydratase
KAM471c_17790	COG2199	diguanylate cyclase activity
KAM471c_17800	COG2885	chlorophyll binding
KAM471c_17820	COG1570	exodeoxyribonuclease VII activity
KAM471c_17850	COG1874	Beta-galactosidase
KAM471c_17850	COG0366	Alpha amylase catalytic
KAM471c_17870	COG0516	GMP reductase activity
KAM471c_17870	COG0517	IMP dehydrogenase activity
KAM471c_17880	COG0519	Catalyzes the synthesis of GMP from XMP
KAM471c_17880	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KAM471c_17920	COG1846	Transcriptional regulator
KAM471c_17960	COG2062	phosphohistidine phosphatase, SixA
KAM471c_17980	COG0697	spore germination
KAM471c_18000	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
KAM471c_18010	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KAM471c_18030	COG4591	ABC-type transport system involved in lipoprotein release permease component
KAM471c_18040	COG1136	(ABC) transporter
KAM471c_18050	COG4591	ABC-type transport system involved in lipoprotein release permease component
KAM471c_18060	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KAM471c_18080	COG0544	peptidyl-prolyl cis-trans isomerase activity
KAM471c_18090	COG0740	serine-type endopeptidase activity
KAM471c_18100	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KAM471c_18110	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KAM471c_18120	COG0776	regulation of translation
KAM471c_18130	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KAM471c_18140	COG0488	(ABC) transporter
KAM471c_18150	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KAM471c_18160	COG3162	membrane
KAM471c_18190	COG1024	Enoyl-CoA hydratase
KAM471c_18200	COG1115	amino acid carrier protein
KAM471c_18220	COG3228	Belongs to the MtfA family
KAM471c_18230	COG1584	GPR1 FUN34 yaaH family protein
KAM471c_18280	COG1024	Enoyl-CoA hydratase
KAM471c_18290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KAM471c_18300	COG1960	acyl-CoA dehydrogenase activity
KAM471c_18320	COG1960	acyl-CoA dehydrogenase activity
KAM471c_18330	COG1024	Enoyl-CoA hydratase
KAM471c_18340	COG1024	Enoyl-CoA hydratase
KAM471c_18360	COG1028	Short-chain dehydrogenase reductase Sdr
KAM471c_18380	COG0730	response to heat
KAM471c_18400	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAM471c_18410	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAM471c_18420	COG1129	ABC transporter
KAM471c_18430	COG3385	transposase activity
KAM471c_18440	COG1879	ABC-type sugar transport system periplasmic component
KAM471c_18460	COG0583	DNA-binding transcription factor activity
KAM471c_18490	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KAM471c_18500	COG0243	molybdopterin cofactor binding
KAM471c_18530	COG0583	DNA-binding transcription factor activity
KAM471c_18540	COG2723	6-phospho-beta-galactosidase activity
KAM471c_18560	COG0583	DNA-binding transcription factor activity
KAM471c_18600	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KAM471c_18610	COG0673	inositol 2-dehydrogenase activity
KAM471c_18620	COG0583	DNA-binding transcription factor activity
KAM471c_18640	COG1560	Kdo2-lipid A biosynthetic process
KAM471c_18650	COG1560	Kdo2-lipid A biosynthetic process
KAM471c_18680	COG0417	DNA replication proofreading
KAM471c_18690	COG0534	Mate efflux family protein
KAM471c_18710	COG0307	riboflavin synthase, alpha
KAM471c_18740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAM471c_18750	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KAM471c_18760	COG0697	spore germination
KAM471c_18770	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KAM471c_18830	COG0675	Transposase, IS605 OrfB family
KAM471c_18840	COG2996	Protein conserved in bacteria
KAM471c_18870	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KAM471c_18880	COG3099	Belongs to the UPF0263 family
KAM471c_18890	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KAM471c_18900	COG2894	cell division
KAM471c_18910	COG0850	regulation of cytokinetic process
KAM471c_18920	COG3100	YcgL domain-containing protein
KAM471c_18930	COG2951	lytic endotransglycosylase activity
KAM471c_18940	COG3385	transposase activity
KAM471c_18950	COG1760	l-serine dehydratase
KAM471c_18960	COG1760	l-serine dehydratase
KAM471c_18970	COG3123	guanosine phosphorylase activity
KAM471c_18980	COG1301	dicarboxylic acid transport
KAM471c_19010	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KAM471c_19020	COG2067	long-chain fatty acid transport protein
KAM471c_19030	COG2067	long-chain fatty acid transport protein
KAM471c_19050	COG1595	DNA-templated transcription, initiation
KAM471c_19080	COG2304	oxidoreductase activity
KAM471c_19120	COG0714	Associated with various cellular activities
KAM471c_19130	COG0183	Belongs to the thiolase family
KAM471c_19140	COG1024	Enoyl-CoA hydratase
KAM471c_19140	COG1250	3-hydroxyacyl-CoA dehydrogenase
KAM471c_19160	COG4681	YaeQ
KAM471c_19180	COG3385	transposase activity
KAM471c_19190	COG3335	DDE superfamily endonuclease
KAM471c_19230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAM471c_19260	COG3134	Outer membrane lipoprotein
KAM471c_19280	COG0675	Transposase, IS605 OrfB family
KAM471c_19290	COG0318	PFAM AMP-dependent synthetase and ligase
KAM471c_19300	COG2378	regulation of single-species biofilm formation
KAM471c_19320	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KAM471c_19320	COG0140	phosphoribosyl-ATP diphosphatase activity
KAM471c_19330	COG0107	imidazoleglycerol-phosphate synthase activity
KAM471c_19340	COG2198	Histidine kinase
KAM471c_19340	COG2205	protein histidine kinase activity
KAM471c_19340	COG0784	Response regulator, receiver
KAM471c_19350	COG2199	diguanylate cyclase activity
KAM471c_19360	COG3437	response regulator, receiver
KAM471c_19370	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KAM471c_19380	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KAM471c_19390	COG0131	Imidazoleglycerol-phosphate dehydratase
KAM471c_19390	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KAM471c_19400	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KAM471c_19410	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KAM471c_19420	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KAM471c_19440	COG1199	ATP-dependent helicase activity
KAM471c_19450	COG1214	PFAM Peptidase M22, glycoprotease
KAM471c_19470	COG0596	Alpha beta hydrolase
KAM471c_19480	COG0318	PFAM AMP-dependent synthetase and ligase
KAM471c_19510	COG0697	spore germination
KAM471c_19530	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KAM471c_19540	COG2832	Protein of unknown function (DUF454)
KAM471c_19550	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KAM471c_19570	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KAM471c_19580	COG0583	DNA-binding transcription factor activity
KAM471c_19660	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KAM471c_19690	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KAM471c_19700	COG3077	Addiction module antitoxin, RelB DinJ family
KAM471c_19750	COG0697	spore germination
KAM471c_19810	COG3621	Patatin-like phospholipase
KAM471c_19910	COG5433	transposase activity
KAM471c_19940	COG3314	Sporulation integral membrane protein YlbJ
KAM471c_19950	COG3385	transposase activity
KAM471c_19960	COG3039	Transposase
KAM471c_19970	COG2197	response regulator
KAM471c_19980	COG0517	IMP dehydrogenase activity
KAM471c_19980	COG0617	tRNA 3'-terminal CCA addition
KAM471c_19980	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KAM471c_19990	COG1643	Atp-dependent helicase
KAM471c_20010	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KAM471c_20030	COG0675	Transposase, IS605 OrfB family
KAM471c_20060	COG3437	response regulator, receiver
KAM471c_20070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KAM471c_20080	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
KAM471c_20090	COG0709	Synthesizes selenophosphate from selenide and ATP
KAM471c_20130	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KAM471c_20140	COG0840	transmembrane signaling receptor activity
KAM471c_20150	COG1254	Belongs to the acylphosphatase family
KAM471c_20180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM471c_20180	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM471c_20190	COG0489	protein tyrosine kinase activity
KAM471c_20200	COG0572	uridine kinase
KAM471c_20210	COG0717	Belongs to the dCTP deaminase family
KAM471c_20220	COG0306	phosphate transporter
KAM471c_20250	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM471c_20360	COG2948	multi-organism process
KAM471c_20380	COG0583	DNA-binding transcription factor activity
KAM471c_20390	COG1846	Transcriptional regulator
KAM471c_20430	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KAM471c_20460	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KAM471c_20480	COG0583	DNA-binding transcription factor activity
KAM471c_20500	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KAM471c_20510	COG0625	glutathione transferase activity
KAM471c_20640	COG3385	transposase activity
KAM471c_20660	COG4584	PFAM Integrase catalytic
KAM471c_20670	COG1484	DNA-dependent DNA replication
KAM471c_20680	COG0840	transmembrane signaling receptor activity
KAM471c_20730	COG1530	ribonuclease E activity
KAM471c_20740	COG0564	pseudouridine synthase activity
KAM471c_20780	COG1399	metal-binding, possibly nucleic acid-binding protein
KAM471c_20790	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KAM471c_20800	COG0416	fatty acid biosynthetic process
KAM471c_20810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KAM471c_20830	COG1028	Short-chain dehydrogenase reductase Sdr
KAM471c_20840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KAM471c_20850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KAM471c_20860	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KAM471c_20870	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KAM471c_20880	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KAM471c_20890	COG0470	DNA polymerase III
KAM471c_20900	COG0084	hydrolase, TatD family'
KAM471c_20930	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
KAM471c_20930	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KAM471c_20940	COG3008	intermembrane lipid transfer
KAM471c_20950	COG2995	paraquat-inducible protein a
KAM471c_20980	COG3141	response to X-ray
KAM471c_21180	COG3039	Transposase
KAM471c_21190	COG0456	acetyltransferase
KAM471c_21210	COG4128	Pfam Zonular occludens toxin
KAM471c_21220	COG1067	ATP-dependent peptidase activity
KAM471c_21230	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KAM471c_21260	COG0488	(ABC) transporter
KAM471c_21280	COG0116	Belongs to the methyltransferase superfamily
KAM471c_21280	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KAM471c_21300	COG0167	dihydroorotate dehydrogenase activity
KAM471c_21320	COG2902	Dehydrogenase
KAM471c_21340	COG0308	aminopeptidase N
KAM471c_21360	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
KAM471c_21370	COG1956	GAF domain-containing protein
KAM471c_21390	COG3278	Belongs to the heme-copper respiratory oxidase family
KAM471c_21420	COG2010	Cytochrome c
KAM471c_21440	COG2217	Heavy metal translocating P-type atpase
KAM471c_21470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KAM471c_21480	COG0589	response to stress
KAM471c_21490	COG0037	tRNA processing
KAM471c_21520	COG0625	glutathione transferase activity
KAM471c_21530	COG1869	D-ribose catabolic process
KAM471c_21540	COG1129	ABC transporter
KAM471c_21550	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAM471c_21560	COG1879	ABC-type sugar transport system periplasmic component
KAM471c_21570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM471c_21580	COG1609	Transcriptional regulator
KAM471c_21610	COG5001	Diguanylate cyclase
KAM471c_21610	COG3300	MHYT domain
KAM471c_21680	COG0776	regulation of translation
KAM471c_21690	COG0072	phenylalanine-tRNA ligase activity
KAM471c_21690	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM471c_21700	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KAM471c_21710	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KAM471c_21720	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KAM471c_21730	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KAM471c_21740	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KAM471c_21820	COG5433	transposase activity
KAM471c_21860	COG0675	Transposase, IS605 OrfB family
KAM471c_21910	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KAM471c_21930	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KAM471c_21940	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KAM471c_21950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KAM471c_21960	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
KAM471c_21970	COG3313	Fe-S protein
KAM471c_21980	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KAM471c_21980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KAM471c_21980	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KAM471c_21990	COG1105	Belongs to the carbohydrate kinase PfkB family
KAM471c_22000	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM471c_22000	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM471c_22010	COG1609	Transcriptional regulator
KAM471c_22020	COG0814	amino acid
KAM471c_22040	COG5654	RES domain protein
KAM471c_22050	COG0513	Belongs to the DEAD box helicase family
KAM471c_22070	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KAM471c_22080	COG2890	protein-(glutamine-N5) methyltransferase activity
KAM471c_22090	COG2840	Smr protein MutS2
KAM471c_22180	COG2824	Alkylphosphonate utilization operon protein PhnA
KAM471c_22220	COG0675	Transposase, IS605 OrfB family
KAM471c_22310	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KAM471c_22320	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
KAM471c_22340	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KAM471c_22350	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KAM471c_22370	COG0205	6-phosphofructokinase activity
KAM471c_22390	COG1473	amidohydrolase
KAM471c_22400	COG1011	Hydrolase
KAM471c_22410	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KAM471c_22430	COG3593	DNA synthesis involved in DNA repair
KAM471c_22460	COG0583	DNA-binding transcription factor activity
KAM471c_22470	COG0730	response to heat
KAM471c_22480	COG3148	PFAM DTW domain containing protein
KAM471c_22490	COG1181	Belongs to the D-alanine--D-alanine ligase family
KAM471c_22510	COG0386	Belongs to the glutathione peroxidase family
KAM471c_22520	COG0513	Belongs to the DEAD box helicase family
KAM471c_22590	COG2329	Antibiotic biosynthesis monooxygenase
KAM471c_22600	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KAM471c_22640	COG3243	poly(R)-hydroxyalkanoic acid synthase
KAM471c_22650	COG3243	poly(R)-hydroxyalkanoic acid synthase
KAM471c_22670	COG2501	S4 domain
KAM471c_22720	COG1132	(ABC) transporter
KAM471c_22730	COG1132	(ABC) transporter
KAM471c_22750	COG3118	belongs to the thioredoxin family
KAM471c_22760	COG0471	metal ion transport
KAM471c_22790	COG0058	SHG alpha-glucan phosphorylase activity
KAM471c_22850	COG0814	amino acid
KAM471c_22860	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KAM471c_22870	COG0514	ATP-dependent DNA helicase (RecQ)
KAM471c_22880	COG2766	serine protein kinase
KAM471c_22890	COG2718	Belongs to the UPF0229 family
KAM471c_22900	COG2719	SpoVR family
KAM471c_22910	COG2186	Transcriptional regulator
KAM471c_22920	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KAM471c_22930	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KAM471c_22940	COG0586	Pfam SNARE associated Golgi protein
KAM471c_22960	COG0556	nucleotide-excision repair
KAM471c_22980	COG0569	domain protein
KAM471c_22980	COG2985	domain, Protein
KAM471c_22990	COG0739	heme binding
KAM471c_22990	COG0741	lytic transglycosylase activity
KAM471c_22990	COG1196	nuclear chromosome segregation
KAM471c_23000	COG3181	Tripartite tricarboxylate transporter family receptor
KAM471c_23030	COG4565	transcriptional regulatory protein
KAM471c_23040	COG3290	protein histidine kinase activity
KAM471c_23050	COG1846	Transcriptional regulator
KAM471c_23050	COG1940	carbohydrate kinase activity
KAM471c_23060	COG0840	transmembrane signaling receptor activity
KAM471c_23070	COG3012	SEC-C Motif Domain Protein
KAM471c_23080	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KAM471c_23090	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KAM471c_23100	COG0247	lactate metabolic process
KAM471c_23140	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
KAM471c_23150	COG0437	4 iron, 4 sulfur cluster binding
KAM471c_23160	COG3301	Polysulphide reductase, NrfD
KAM471c_23180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KAM471c_23190	COG3088	subunit of a heme lyase
KAM471c_23190	COG4235	cytochrome complex assembly
KAM471c_23210	COG3046	protein related to deoxyribodipyrimidine photolyase
KAM471c_23220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAM471c_23250	COG0617	tRNA 3'-terminal CCA addition
KAM471c_23250	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KAM471c_23250	COG0517	IMP dehydrogenase activity
KAM471c_23270	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KAM471c_23280	COG0583	DNA-binding transcription factor activity
KAM471c_23300	COG4774	siderophore transport
KAM471c_23310	COG2203	Gaf domain
KAM471c_23310	COG2199	diguanylate cyclase activity
KAM471c_23320	COG2200	EAL domain
KAM471c_23330	COG4977	sequence-specific DNA binding
KAM471c_23330	COG1917	Cupin 2, conserved barrel domain protein
KAM471c_23340	COG0583	DNA-binding transcription factor activity
KAM471c_23350	COG2910	NAD(P)H-binding
KAM471c_23380	COG0626	cystathionine gamma-synthase activity
KAM471c_23390	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KAM471c_23420	COG2226	methyltransferase
KAM471c_23440	COG3250	beta-galactosidase activity
KAM471c_23450	COG2223	nitrite transmembrane transporter activity
KAM471c_23530	COG0629	single-stranded DNA binding
KAM471c_23690	COG3550	peptidyl-serine autophosphorylation
KAM471c_23700	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
KAM471c_23730	COG2723	6-phospho-beta-galactosidase activity
KAM471c_23740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM471c_23740	COG2190	(PTS) system
KAM471c_23740	COG1263	PTS System
KAM471c_23750	COG1737	Transcriptional regulator
KAM471c_23780	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM471c_23840	COG1435	thymidine kinase activity
KAM471c_23850	COG1757	Na H antiporter
KAM471c_23860	COG2916	Histone family protein nucleoid-structuring protein H-NS
KAM471c_23870	COG2096	Adenosyltransferase
KAM471c_23880	COG3530	Putative quorum-sensing-regulated virulence factor
KAM471c_23890	COG0602	queuosine metabolic process
KAM471c_23900	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KAM471c_23940	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KAM471c_23960	COG0776	regulation of translation
KAM471c_23970	COG0539	negative regulation of cytoplasmic translation
KAM471c_23980	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KAM471c_23990	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KAM471c_24050	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KAM471c_24060	COG5001	Diguanylate cyclase
KAM471c_24060	COG3300	MHYT domain
KAM471c_24080	COG0583	DNA-binding transcription factor activity
KAM471c_24090	COG0745	RESPONSE REGULATOR receiver
KAM471c_24140	COG4989	oxidoreductase activity
KAM471c_24150	COG0724	RNA recognition motif
KAM471c_24170	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
KAM471c_24190	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KAM471c_24240	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM471c_24260	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KAM471c_24270	COG1360	Flagellar Motor Protein
KAM471c_24280	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM471c_24290	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM471c_24300	COG0649	NAD binding
KAM471c_24300	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM471c_24330	COG1034	ATP synthesis coupled electron transport
KAM471c_24340	COG1034	ATP synthesis coupled electron transport
KAM471c_24350	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KAM471c_24360	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM471c_24370	COG0839	Belongs to the complex I subunit 6 family
KAM471c_24380	COG0713	ATP synthesis coupled electron transport
KAM471c_24400	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM471c_24410	COG1007	ATP synthesis coupled electron transport
KAM471c_24420	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KAM471c_24420	COG0047	phosphoribosylformylglycinamidine synthase activity
KAM471c_24430	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KAM471c_24450	COG1645	bacterial-type flagellum-dependent swarming motility
KAM471c_24460	COG1160	GTP binding
KAM471c_24470	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAM471c_24480	COG2976	Protein conserved in bacteria
KAM471c_24490	COG0124	histidyl-tRNA synthetase
KAM471c_24510	COG1426	Protein conserved in bacteria
KAM471c_24530	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KAM471c_24540	COG0105	UTP biosynthetic process
KAM471c_24570	COG0633	Ferredoxin
KAM471c_24580	COG0443	Heat shock 70 kDa protein
KAM471c_24590	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KAM471c_24610	COG0822	iron-sulfur transferase activity
KAM471c_24620	COG1104	cysteine desulfurase activity
KAM471c_24650	COG3154	lipid carrier protein
KAM471c_24660	COG0826	peptidase U32
KAM471c_24670	COG0826	peptidase U32
KAM471c_24690	COG2897	thiosulfate sulfurtransferase activity
KAM471c_24700	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAM471c_24710	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAM471c_24720	COG1862	Preprotein translocase
KAM471c_24730	COG0343	queuine tRNA-ribosyltransferase activity
KAM471c_24740	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KAM471c_24750	COG0517	IMP dehydrogenase activity
KAM471c_24760	COG0450	alkyl hydroperoxide reductase
KAM471c_24770	COG3634	alkyl hydroperoxide reductase activity
KAM471c_24820	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KAM471c_24820	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KAM471c_24830	COG0509	glycine decarboxylation via glycine cleavage system
KAM471c_24840	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KAM471c_24850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KAM471c_24860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KAM471c_24890	COG2814	Major facilitator Superfamily
KAM471c_24900	COG0444	Belongs to the ABC transporter superfamily
KAM471c_24910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAM471c_24920	COG0601	transmembrane transport
KAM471c_24940	COG0625	glutathione transferase activity
KAM471c_24950	COG0625	glutathione transferase activity
KAM471c_24970	COG0483	inositol monophosphate 1-phosphatase activity
KAM471c_25000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KAM471c_25010	COG2056	Na+-H+ antiporter family
KAM471c_25020	COG2814	Major facilitator Superfamily
KAM471c_25030	COG0583	DNA-binding transcription factor activity
KAM471c_25040	COG5001	Diguanylate cyclase
KAM471c_25070	COG2050	protein possibly involved in aromatic compounds catabolism
KAM471c_25090	COG0247	lactate metabolic process
KAM471c_25090	COG0277	FAD linked oxidase domain protein
KAM471c_25130	COG1253	flavin adenine dinucleotide binding
KAM471c_25140	COG1902	pentaerythritol trinitrate reductase activity
KAM471c_25160	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KAM471c_25170	COG0647	UMP catabolic process
KAM471c_25190	COG0367	asparagine synthase
KAM471c_25220	COG0625	glutathione transferase activity
KAM471c_25240	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KAM471c_25270	COG0564	pseudouridine synthase activity
KAM471c_25280	COG5001	Diguanylate cyclase
KAM471c_25300	COG0840	transmembrane signaling receptor activity
KAM471c_25310	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KAM471c_25390	COG0670	Belongs to the BI1 family
KAM471c_25400	COG1289	transmembrane transporter activity
KAM471c_25410	COG2920	part of a sulfur-relay system
KAM471c_25420	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
KAM471c_25430	COG0285	dihydrofolate synthase activity
KAM471c_25440	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KAM471c_25450	COG0101	tRNA pseudouridine synthase activity
KAM471c_25470	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KAM471c_25480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KAM471c_25500	COG1464	Belongs to the NlpA lipoprotein family
KAM471c_25550	COG1119	ATPase activity
KAM471c_25560	COG0574	Belongs to the PEP-utilizing enzyme family
KAM471c_25560	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KAM471c_25570	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KAM471c_25590	COG1113	amino acid transport
KAM471c_25700	COG1242	4 iron, 4 sulfur cluster binding
KAM471c_25710	COG0070	glutamate synthase
KAM471c_25710	COG0067	glutamate synthase
KAM471c_25710	COG0069	glutamate synthase activity
KAM471c_25720	COG0493	'glutamate synthase
KAM471c_25730	COG1126	abc transporter atp-binding protein
KAM471c_25740	COG0765	amino acid transport
KAM471c_25750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM471c_25780	COG4104	PAAR repeat-containing protein
KAM471c_25800	COG0513	Belongs to the DEAD box helicase family
KAM471c_25880	COG3706	GGDEF domain
KAM471c_25890	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KAM471c_25900	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KAM471c_25910	COG0505	Belongs to the CarA family
KAM471c_25920	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KAM471c_25940	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KAM471c_25950	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KAM471c_25960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KAM471c_25970	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KAM471c_25980	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAM471c_25990	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
KAM471c_26050	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KAM471c_26070	COG0023	Translation Initiation Factor
KAM471c_26080	COG2119	membrane
KAM471c_26100	COG3039	Transposase
KAM471c_26110	COG3385	transposase activity
KAM471c_26120	COG3385	transposase activity
KAM471c_26140	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KAM471c_26160	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAM471c_26170	COG2261	transglycosylase associated protein
KAM471c_26180	COG1309	transcriptional regulator
KAM471c_26190	COG0604	alcohol dehydrogenase
KAM471c_26220	COG0583	DNA-binding transcription factor activity
KAM471c_26310	COG4584	PFAM Integrase catalytic
KAM471c_26320	COG1484	DNA-dependent DNA replication
KAM471c_26480	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KAM471c_26570	COG2801	Transposase and inactivated derivatives
KAM471c_26580	COG3385	transposase activity
KAM471c_26590	COG3328	transposase activity
KAM471c_26620	COG0322	excinuclease ABC activity
KAM471c_26630	COG2197	response regulator
KAM471c_26640	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KAM471c_26650	COG2835	tetraacyldisaccharide 4'-kinase activity
KAM471c_26660	COG1663	tetraacyldisaccharide 4'-kinase activity
KAM471c_26670	COG1132	(ABC) transporter
KAM471c_26680	COG2333	competence protein COMEC
KAM471c_26680	COG0658	competence protein
KAM471c_26730	COG0433	COG0433 Predicted ATPase
KAM471c_26740	COG1448	Aminotransferase
KAM471c_26800	COG1199	ATP-dependent helicase activity
KAM471c_26820	COG0123	including yeast histone deacetylase and acetoin utilization protein
KAM471c_26830	COG0477	Major facilitator Superfamily
KAM471c_26840	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KAM471c_26850	COG1785	Belongs to the alkaline phosphatase family
KAM471c_26890	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KAM471c_26900	COG3706	GGDEF domain
KAM471c_26920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM471c_26930	COG0765	amino acid transport
KAM471c_26940	COG1126	abc transporter atp-binding protein
KAM471c_26960	COG0531	amino acid
KAM471c_26990	COG1253	flavin adenine dinucleotide binding
KAM471c_27000	COG0704	Plays a role in the regulation of phosphate uptake
KAM471c_27010	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KAM471c_27020	COG0581	inorganic phosphate transmembrane transporter activity
KAM471c_27030	COG0573	inorganic phosphate transmembrane transporter activity
KAM471c_27040	COG0590	tRNA wobble adenosine to inosine editing
KAM471c_27050	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KAM471c_27090	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KAM471c_27100	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KAM471c_27110	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KAM471c_27120	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KAM471c_27170	COG2716	regulation of RNA biosynthetic process
KAM471c_27180	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KAM471c_27200	COG2239	Acts as a magnesium transporter
KAM471c_27240	COG3951	Flagellar rod assembly protein muramidase FlgJ
KAM471c_27240	COG1705	Flagellar rod assembly protein muramidase FlgJ
KAM471c_27250	COG1706	bacterial-type flagellum-dependent cell motility
KAM471c_27260	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KAM471c_27290	COG4786	Flagellar basal body rod
KAM471c_27320	COG1815	bacterial-type flagellum-dependent cell motility
KAM471c_27330	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KAM471c_27340	COG0784	Response regulator, receiver
KAM471c_27340	COG0835	chemotaxis
KAM471c_27350	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
KAM471c_27380	COG0622	Phosphoesterase
KAM471c_27390	COG4166	transmembrane transport
KAM471c_27430	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KAM471c_27440	COG0675	Transposase, IS605 OrfB family
KAM471c_27460	COG0697	spore germination
KAM471c_27470	COG4166	transmembrane transport
KAM471c_27520	COG1278	Cold shock
KAM471c_27550	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KAM471c_27600	COG3132	Protein of unknown function, DUF480
KAM471c_27620	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAM471c_27670	COG0675	Transposase, IS605 OrfB family
KAM471c_27690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KAM471c_27710	COG3039	Transposase
KAM471c_27760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KAM471c_27890	COG1091	dTDP-4-dehydrorhamnose reductase activity
KAM471c_27940	COG1737	Transcriptional regulator
KAM471c_27950	COG0469	pyruvate kinase activity
KAM471c_27970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM471c_27980	COG1960	acyl-CoA dehydrogenase activity
KAM471c_28000	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KAM471c_28060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM471c_28070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM471c_28080	COG1309	transcriptional regulator
KAM471c_28110	COG1946	Acyl-CoA thioesterase
KAM471c_28140	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KAM471c_28160	COG0009	L-threonylcarbamoyladenylate synthase
KAM471c_28170	COG0613	PHP domain protein
KAM471c_28180	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KAM471c_28190	COG0512	Glutamine amidotransferase of anthranilate synthase
KAM471c_28190	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KAM471c_28200	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KAM471c_28210	COG0134	indole-3-glycerol-phosphate synthase activity
KAM471c_28210	COG0135	phosphoribosylanthranilate isomerase activity
KAM471c_28220	COG0133	tryptophan synthase activity
KAM471c_28230	COG0159	tryptophan synthase activity
KAM471c_28260	COG5433	transposase activity
KAM471c_28290	COG1396	sequence-specific DNA binding
KAM471c_28300	COG3550	peptidyl-serine autophosphorylation
KAM471c_28370	COG5507	3-demethylubiquinone-9 3-methyltransferase
KAM471c_28380	COG2814	Major facilitator Superfamily
KAM471c_28390	COG0109	protoheme IX farnesyltransferase activity
KAM471c_28400	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KAM471c_28410	COG1845	cytochrome c oxidase, subunit III
KAM471c_28420	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KAM471c_28430	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KAM471c_28440	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KAM471c_28450	COG0583	DNA-binding transcription factor activity
KAM471c_28480	COG0675	Transposase, IS605 OrfB family
KAM471c_28500	COG1846	Transcriptional regulator
KAM471c_28530	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
KAM471c_28560	COG0745	RESPONSE REGULATOR receiver
KAM471c_28580	COG0708	Exodeoxyribonuclease III
KAM471c_28610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM471c_28620	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM471c_28650	COG0095	Lipoate-protein ligase
KAM471c_28710	COG0640	Transcriptional regulator
KAM471c_28730	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAM471c_28750	COG1285	pathogenesis
KAM471c_28820	COG0484	heat shock protein binding
KAM471c_28830	COG0443	Heat shock 70 kDa protein
KAM471c_28840	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KAM471c_28860	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KAM471c_28870	COG3706	GGDEF domain
KAM471c_28880	COG0497	DNA recombination
KAM471c_28900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM471c_28910	COG0577	efflux transmembrane transporter activity
KAM471c_28910	COG1136	(ABC) transporter
KAM471c_28920	COG1538	Outer membrane efflux protein
KAM471c_28930	COG2375	cellular response to nickel ion
KAM471c_28940	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAM471c_28950	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAM471c_28960	COG2916	Histone family protein nucleoid-structuring protein H-NS
KAM471c_28970	COG0583	DNA-binding transcription factor activity
KAM471c_28980	COG3048	D-serine ammonia-lyase activity
KAM471c_29000	COG0538	isocitrate dehydrogenase activity
KAM471c_29090	COG0456	acetyltransferase
KAM471c_29100	COG1187	pseudouridine synthase activity
KAM471c_29120	COG0482	sulfurtransferase activity
KAM471c_29130	COG2915	High frequency lysogenization protein hflD homolog
KAM471c_29140	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KAM471c_29150	COG2850	peptidyl-arginine hydroxylation
KAM471c_29170	COG1196	nuclear chromosome segregation
KAM471c_29170	COG3264	Mechanosensitive ion channel
KAM471c_29250	COG0281	malic enzyme
KAM471c_29260	COG0746	molybdenum cofactor guanylyltransferase activity
KAM471c_29270	COG1763	Mo-molybdopterin cofactor biosynthetic process
KAM471c_29280	COG1289	transmembrane transporter activity
KAM471c_29300	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KAM471c_29360	COG3220	belongs to the UPF0276 family
KAM471c_29380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KAM471c_29420	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KAM471c_29430	COG0083	homoserine kinase activity
KAM471c_29450	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
KAM471c_29460	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
KAM471c_29490	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KAM471c_29510	COG0745	RESPONSE REGULATOR receiver
KAM471c_29520	COG4988	ABC transporter
KAM471c_29530	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KAM471c_29570	COG1720	tRNA m6t6A37 methyltransferase activity
KAM471c_29600	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KAM471c_29610	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KAM471c_29620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM471c_29640	COG2190	(PTS) system
KAM471c_29650	COG3038	cytochrome b561
KAM471c_29670	COG0420	3'-5' exonuclease activity
KAM471c_29690	COG1247	-acetyltransferase
KAM471c_29700	COG2974	May be involved in recombination
KAM471c_29720	COG0405	Gamma-glutamyltransferase
KAM471c_29740	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KAM471c_29740	COG4651	solute:proton antiporter activity
KAM471c_29820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAM471c_29830	COG1917	Cupin 2, conserved barrel domain protein
KAM471c_29830	COG1396	sequence-specific DNA binding
KAM471c_29870	COG0531	amino acid
KAM471c_29880	COG0531	amino acid
KAM471c_29900	COG5433	transposase activity
KAM471c_29910	COG1283	sodium-dependent phosphate transmembrane transporter activity
KAM471c_29930	COG3384	dioxygenase
KAM471c_29940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM471c_29940	COG2205	protein histidine kinase activity
KAM471c_29980	COG0745	RESPONSE REGULATOR receiver
KAM471c_29990	COG0582	viral genome integration into host DNA
KAM471c_30060	COG1388	LysM domain
KAM471c_30060	COG1376	ErfK ybiS ycfS ynhG family protein
KAM471c_30090	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
KAM471c_30100	COG0791	NLP P60 protein
KAM471c_30120	COG3118	belongs to the thioredoxin family
KAM471c_30140	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KAM471c_30150	COG0788	formyltetrahydrofolate deformylase activity
KAM471c_30210	COG0741	lytic transglycosylase activity
KAM471c_30210	COG1196	nuclear chromosome segregation
KAM471c_30210	COG0739	heme binding
KAM471c_30220	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KAM471c_30230	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KAM471c_30240	COG0673	inositol 2-dehydrogenase activity
KAM471c_30310	COG1032	radical SAM domain protein
KAM471c_30320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM471c_30340	COG3706	GGDEF domain
KAM471c_30350	COG1752	Esterase of the alpha-beta hydrolase superfamily
KAM471c_30360	COG0733	neurotransmitter:sodium symporter activity
KAM471c_30420	COG0281	malic enzyme
KAM471c_30440	COG0281	malic enzyme
KAM471c_30450	COG2207	Transcriptional regulator
KAM471c_30460	COG0534	Mate efflux family protein
KAM471c_30490	COG2233	PERMEase
KAM471c_30500	COG0095	Lipoate-protein ligase
KAM471c_30510	COG1115	amino acid carrier protein
KAM471c_30520	COG0019	diaminopimelate decarboxylase activity
KAM471c_30540	COG0678	peroxiredoxin activity
KAM471c_30550	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KAM471c_30570	COG1126	abc transporter atp-binding protein
KAM471c_30580	COG0765	amino acid transport
KAM471c_30590	COG4597	amino acid ABC transporter
KAM471c_30600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM471c_30630	COG1131	(ABC) transporter
KAM471c_30640	COG0545	Peptidyl-prolyl cis-trans isomerase
KAM471c_30680	COG4783	chaperone-mediated protein folding
KAM471c_30700	COG5002	protein histidine kinase activity
KAM471c_30710	COG0745	RESPONSE REGULATOR receiver
KAM471c_30720	COG0346	lactoylglutathione lyase activity
KAM471c_30730	COG3706	GGDEF domain
KAM471c_30740	COG3284	Transcriptional regulator
KAM471c_30770	COG0697	spore germination
KAM471c_30790	COG0667	Aldo Keto reductase
KAM471c_30820	COG3290	protein histidine kinase activity
KAM471c_30840	COG1566	PFAM secretion protein HlyD family protein
KAM471c_30890	COG0602	queuosine metabolic process
KAM471c_30900	COG1328	CTP reductase activity
KAM471c_30920	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KAM471c_30930	COG3115	cell septum assembly
KAM471c_30940	COG1196	nuclear chromosome segregation
KAM471c_30960	COG2860	membrane
KAM471c_30980	COG3108	Peptidase M15
KAM471c_30990	COG2989	Protein conserved in bacteria
KAM471c_31020	COG0463	Glycosyl transferase, family 2
KAM471c_31050	COG0366	Alpha amylase catalytic
KAM471c_31130	COG3706	GGDEF domain
KAM471c_31140	COG0037	tRNA processing
KAM471c_31150	COG3590	peptidase
KAM471c_31170	COG0488	(ABC) transporter
KAM471c_31190	COG0531	amino acid
KAM471c_31200	COG0814	amino acid
KAM471c_31230	COG0825	malonyl-CoA metabolic process
KAM471c_31250	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KAM471c_31260	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAM471c_31270	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAM471c_31280	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KAM471c_31290	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAM471c_31320	COG0750	zinc metalloprotease
KAM471c_31330	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KAM471c_31340	COG0575	Belongs to the CDS family
KAM471c_31350	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KAM471c_31360	COG0233	cytoplasmic translational termination
KAM471c_31370	COG0528	UMP kinase activity
KAM471c_31380	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KAM471c_31390	COG0052	Belongs to the universal ribosomal protein uS2 family
KAM471c_31400	COG0024	Methionine aminopeptidase
KAM471c_31410	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KAM471c_31420	COG2171	N-acyltransferase activity
KAM471c_31440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM471c_31440	COG1263	PTS System
KAM471c_31460	COG4580	involved in the transport of maltose and maltodextrins
KAM471c_31480	COG0564	pseudouridine synthase activity
KAM471c_31490	COG3098	single-species biofilm formation
KAM471c_31540	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
KAM471c_31560	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KAM471c_31560	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KAM471c_31590	COG1611	Belongs to the LOG family
KAM471c_31610	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KAM471c_31620	COG0473	3-isopropylmalate dehydrogenase activity
KAM471c_31640	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
KAM471c_31670	COG0583	DNA-binding transcription factor activity
KAM471c_31680	COG0840	transmembrane signaling receptor activity
KAM471c_31690	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KAM471c_31720	COG1477	protein flavinylation
KAM471c_31730	COG2871	sodium ion transport
KAM471c_31740	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM471c_31750	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM471c_31760	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM471c_31770	COG1805	sodium ion transport
KAM471c_31780	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM471c_31790	COG0271	Belongs to the BolA IbaG family
KAM471c_31800	COG2813	Specifically methylates the guanine in position
KAM471c_31820	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KAM471c_31840	COG2211	Major facilitator Superfamily
KAM471c_31860	COG1666	GTP binding
KAM471c_31870	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KAM471c_31890	COG0659	secondary active sulfate transmembrane transporter activity
KAM471c_31910	COG5000	phosphorelay sensor kinase activity
KAM471c_31910	COG5002	protein histidine kinase activity
KAM471c_31930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM471c_31940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM471c_31960	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KAM471c_31980	COG1151	hydroxylamine reductase activity
KAM471c_31990	COG0783	Belongs to the Dps family
KAM471c_32040	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KAM471c_32070	COG4221	oxidoreductase activity
KAM471c_32090	COG0415	Belongs to the DNA photolyase family
KAM471c_32100	COG0789	Transcriptional regulator
KAM471c_32110	COG3272	Protein of unknown function (DUF1722)
KAM471c_32160	COG0077	Prephenate dehydratase
KAM471c_32160	COG1605	Chorismate mutase
KAM471c_32250	COG2133	pyrroloquinoline quinone binding
KAM471c_32270	COG1349	DNA-binding transcription factor activity
KAM471c_32280	COG2084	Dehydrogenase
KAM471c_32300	COG0235	Class ii aldolase
KAM471c_32310	COG3622	Belongs to the hyi family
KAM471c_32320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KAM471c_32330	COG2610	gluconate transmembrane transporter activity
KAM471c_32380	COG0300	oxidoreductase activity
KAM471c_32430	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KAM471c_32490	COG0826	peptidase U32
KAM471c_32500	COG1280	lysine exporter protein (LysE YggA)
KAM471c_32520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KAM471c_32540	COG2199	diguanylate cyclase activity
KAM471c_32540	COG2200	EAL domain
KAM471c_32540	COG2203	Gaf domain
KAM471c_32630	COG1566	PFAM secretion protein HlyD family protein
KAM471c_32650	COG0114	fumarate hydratase activity
KAM471c_32670	COG0506	proline dehydrogenase activity
KAM471c_32670	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KAM471c_32670	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KAM471c_32680	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KAM471c_32710	COG0737	Belongs to the 5'-nucleotidase family
KAM471c_32750	COG2204	response regulator
KAM471c_32760	COG0545	Peptidyl-prolyl cis-trans isomerase
KAM471c_32780	COG2900	Belongs to the SlyX family
KAM471c_32790	COG1047	Peptidyl-prolyl cis-trans
KAM471c_32800	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KAM471c_32820	COG0835	chemotaxis
KAM471c_32820	COG0784	Response regulator, receiver
KAM471c_32830	COG0429	hydrolase of the alpha beta-hydrolase fold
KAM471c_32840	COG2203	Gaf domain
KAM471c_32840	COG3706	GGDEF domain
KAM471c_32840	COG4251	negative regulation of phosphorylation
KAM471c_32840	COG5001	Diguanylate cyclase
KAM471c_32850	COG3089	Belongs to the UPF0270 family
KAM471c_32860	COG3954	Phosphoribulokinase
KAM471c_32890	COG1765	OsmC-like protein
KAM471c_32910	COG2226	methyltransferase
KAM471c_32930	COG2202	Pas domain
KAM471c_32930	COG2205	protein histidine kinase activity
KAM471c_32940	COG2814	Major facilitator Superfamily
KAM471c_32990	COG0748	coenzyme F420 binding
KAM471c_33000	COG3721	Heme iron utilization protein
KAM471c_33020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAM471c_33070	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KAM471c_33090	COG0463	Glycosyl transferase, family 2
KAM471c_33100	COG0739	heme binding
KAM471c_33100	COG0741	lytic transglycosylase activity
KAM471c_33100	COG1196	nuclear chromosome segregation
KAM471c_33110	COG0488	(ABC) transporter
KAM471c_33130	COG2252	PERMEase
KAM471c_33140	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KAM471c_33150	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KAM471c_33160	COG3178	'Phosphotransferase
KAM471c_33170	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KAM471c_33190	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KAM471c_33200	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KAM471c_33220	COG2967	ApaG domain
KAM471c_33230	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KAM471c_33250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KAM471c_33270	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KAM471c_33280	COG3314	Sporulation integral membrane protein YlbJ
KAM471c_33290	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KAM471c_33300	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KAM471c_33310	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KAM471c_33320	COG0142	geranyltranstransferase activity
KAM471c_33330	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
KAM471c_33340	COG0330	HflC and HflK could
KAM471c_33350	COG0330	HflC and HflK could
KAM471c_33360	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KAM471c_33370	COG1923	regulation of RNA biosynthetic process
KAM471c_33380	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KAM471c_33390	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KAM471c_33410	COG0802	atpase or kinase
KAM471c_33420	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KAM471c_33420	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KAM471c_33460	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KAM471c_33470	COG2011	ABC-type metal ion transport system permease component
KAM471c_33490	COG1464	Belongs to the NlpA lipoprotein family
KAM471c_33530	COG0784	Response regulator, receiver
KAM471c_33530	COG2205	protein histidine kinase activity
KAM471c_33560	COG0784	Response regulator, receiver
KAM471c_33560	COG2198	Histidine kinase
KAM471c_33560	COG5002	protein histidine kinase activity
KAM471c_33600	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
KAM471c_33630	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KAM471c_33640	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
KAM471c_33650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KAM471c_33660	COG2716	regulation of RNA biosynthetic process
KAM471c_33670	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KAM471c_33680	COG3013	Belongs to the UPF0304 family
KAM471c_33690	COG3092	negative regulation of chromosome organization
KAM471c_33700	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KAM471c_33710	COG0857	belongs to the CobB CobQ family
KAM471c_33710	COG0280	phosphate acetyltransferase
KAM471c_33720	COG0440	acetolactate synthase activity
KAM471c_33730	COG0028	Belongs to the TPP enzyme family
KAM471c_33750	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KAM471c_33760	COG0671	phosphoesterase, PA-phosphatase related
KAM471c_33780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KAM471c_33790	COG0473	3-isopropylmalate dehydrogenase activity
KAM471c_33800	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KAM471c_33810	COG0066	3-isopropylmalate dehydratase activity
KAM471c_33840	COG4143	(ABC) transporter
KAM471c_33850	COG1178	ABC-type Fe3 transport system permease component
KAM471c_33860	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
KAM471c_33880	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KAM471c_33900	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KAM471c_33920	COG0316	Belongs to the HesB IscA family
KAM471c_33940	COG0038	chloride channel
KAM471c_33950	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KAM471c_33980	COG0671	phosphoesterase, PA-phosphatase related
KAM471c_34010	COG2076	Multidrug Resistance protein
KAM471c_34030	COG0346	lactoylglutathione lyase activity
KAM471c_34040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KAM471c_34050	COG1643	Atp-dependent helicase
KAM471c_34070	COG1489	DNA binding
KAM471c_34080	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KAM471c_34090	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KAM471c_34110	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KAM471c_34120	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KAM471c_34130	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KAM471c_34150	COG0842	Transport permease protein
KAM471c_34160	COG1131	(ABC) transporter
KAM471c_34200	COG0163	prenyltransferase activity
KAM471c_34210	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KAM471c_34220	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KAM471c_34250	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
KAM471c_34280	COG1136	(ABC) transporter
KAM471c_34390	COG0529	Catalyzes the synthesis of activated sulfate
KAM471c_34400	COG0471	metal ion transport
KAM471c_34400	COG3273	potassium ion transport
KAM471c_34410	COG2895	sulfate adenylyltransferase (ATP) activity
KAM471c_34420	COG0175	sulfate reduction
KAM471c_34430	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KAM471c_34430	COG1648	precorrin-2 dehydrogenase activity
KAM471c_34440	COG0330	HflC and HflK could
KAM471c_34450	COG1585	Membrane protein implicated in regulation of membrane protease activity
KAM471c_34480	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KAM471c_34490	COG1940	carbohydrate kinase activity
KAM471c_34500	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KAM471c_34510	COG0126	phosphoglycerate kinase activity
KAM471c_34530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAM471c_34590	COG0583	DNA-binding transcription factor activity
KAM471c_34600	COG0354	folic acid binding
KAM471c_34610	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KAM471c_34630	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KAM471c_34640	COG1595	DNA-templated transcription, initiation
KAM471c_34680	COG0481	GTPase activity
KAM471c_34690	COG0681	Belongs to the peptidase S26 family
KAM471c_34700	COG0571	ribonuclease III activity
KAM471c_34720	COG1381	Involved in DNA repair and RecF pathway recombination
KAM471c_34730	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KAM471c_34740	COG3023	N-Acetylmuramoyl-L-alanine amidase
KAM471c_34750	COG4807	Protein conserved in bacteria
KAM471c_34770	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KAM471c_34780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KAM471c_34790	COG3956	TIGRFAM MazG family protein
KAM471c_34800	COG0504	CTP synthase activity
KAM471c_34810	COG0148	phosphopyruvate hydratase activity
KAM471c_34820	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KAM471c_34830	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KAM471c_34850	COG0585	pseudouridine synthase activity
KAM471c_34860	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KAM471c_34870	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KAM471c_34880	COG1238	metal cluster binding
KAM471c_34890	COG4942	peptidase
KAM471c_34890	COG1388	LysM domain
KAM471c_34920	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KAM471c_34930	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KAM471c_34940	COG1610	YqeY-like protein
KAM471c_34950	COG0358	DNA primase activity
KAM471c_34960	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KAM471c_35040	COG0151	Belongs to the GarS family
KAM471c_35050	COG0138	bifunctional purine biosynthesis protein purh
KAM471c_35080	COG3036	rescue of stalled ribosome
KAM471c_35090	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KAM471c_35100	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KAM471c_35120	COG0673	inositol 2-dehydrogenase activity
KAM471c_35150	COG4991	sh3 domain protein
KAM471c_35160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KAM471c_35190	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KAM471c_35210	COG1028	Short-chain dehydrogenase reductase Sdr
KAM471c_35240	COG1505	serine-type exopeptidase activity
KAM471c_35250	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KAM471c_35260	COG0765	amino acid transport
KAM471c_35270	COG0765	amino acid transport
KAM471c_35280	COG1126	abc transporter atp-binding protein
KAM471c_35290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM471c_35300	COG3174	membrane
KAM471c_35310	COG0110	maltose O-acetyltransferase activity
KAM471c_35370	COG1942	4-Oxalocrotonate Tautomerase
KAM471c_35390	COG0583	DNA-binding transcription factor activity
KAM471c_35400	COG0165	Argininosuccinate lyase
KAM471c_35410	COG0137	argininosuccinate synthase activity
KAM471c_35430	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KAM471c_35440	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KAM471c_35460	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KAM471c_35480	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KAM471c_35550	COG0583	DNA-binding transcription factor activity
KAM471c_35560	COG1380	Effector of murein hydrolase LrgA
KAM471c_35570	COG1346	cytolysis
KAM471c_35580	COG0527	aspartate kinase activity
KAM471c_35580	COG0460	homoserine dehydrogenase
KAM471c_35590	COG0626	cystathionine gamma-synthase activity
KAM471c_35620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM471c_35630	COG0814	amino acid
KAM471c_35640	COG1218	3'(2'),5'-bisphosphate nucleotidase
KAM471c_35650	COG0494	nUDIX hydrolase
KAM471c_35660	COG1011	Hydrolase
KAM471c_35690	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KAM471c_35720	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
KAM471c_35740	COG3156	type II secretion system protein K
KAM471c_35750	COG4795	General secretion pathway protein
KAM471c_35760	COG2165	general secretion pathway protein
KAM471c_35780	COG2165	general secretion pathway protein
KAM471c_35790	COG1459	type II secretion system
KAM471c_35800	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KAM471c_35820	COG3031	protein transport across the cell outer membrane
KAM471c_35840	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KAM471c_35850	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KAM471c_35890	COG3133	Outer membrane lipoprotein
KAM471c_35900	COG3025	triphosphatase activity
KAM471c_35910	COG1392	Phosphate transport regulator
KAM471c_35920	COG0306	phosphate transporter
KAM471c_35930	COG0617	tRNA 3'-terminal CCA addition
KAM471c_35940	COG3409	Peptidoglycan-binding domain 1 protein
KAM471c_35940	COG3267	Type II secretory pathway component ExeA
KAM471c_35960	COG1194	a g-specific adenine glycosylase
KAM471c_35970	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
KAM471c_36000	COG3240	lipase activity
KAM471c_36020	COG3009	Protein conserved in bacteria
KAM471c_36030	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KAM471c_36030	COG3008	intermembrane lipid transfer
KAM471c_36040	COG2995	paraquat-inducible protein a
KAM471c_36060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAM471c_36070	COG3706	GGDEF domain
KAM471c_36070	COG5001	Diguanylate cyclase
KAM471c_36070	COG2203	Gaf domain
KAM471c_36070	COG4251	negative regulation of phosphorylation
KAM471c_36080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KAM471c_36090	COG2813	Specifically methylates the guanine in position
KAM471c_36100	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KAM471c_36110	COG0297	glycogen (starch) synthase activity
KAM471c_36140	COG1757	Na H antiporter
KAM471c_36150	COG0583	DNA-binding transcription factor activity
KAM471c_36170	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KAM471c_36180	COG3842	ATPase activity
KAM471c_36190	COG1176	ABC-type spermidine putrescine transport system, permease component I
KAM471c_36200	COG1177	transmembrane transport
KAM471c_36210	COG1012	belongs to the aldehyde dehydrogenase family
KAM471c_36220	COG0109	protoheme IX farnesyltransferase activity
KAM471c_36280	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KAM471c_36300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KAM471c_36300	COG1565	acr, cog1565
KAM471c_36310	COG1444	tRNA N-acetyltransferase activity
KAM471c_36350	COG1803	Methylglyoxal synthase
KAM471c_36380	COG0252	asparaginase activity
KAM471c_36420	COG1263	PTS System
KAM471c_36420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM471c_36430	COG0366	Alpha amylase catalytic
KAM471c_36440	COG0110	maltose O-acetyltransferase activity
KAM471c_36450	COG1522	sequence-specific DNA binding
KAM471c_36510	COG3068	Protein conserved in bacteria
KAM471c_36530	COG0739	heme binding
KAM471c_36590	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
KAM471c_36600	COG1121	(ABC) transporter
KAM471c_36610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KAM471c_36620	COG0583	DNA-binding transcription factor activity
KAM471c_36640	COG1573	uracil-dna glycosylase
KAM471c_36650	COG2962	Rard protein
KAM471c_36660	COG2827	Endonuclease containing a URI domain
KAM471c_36690	COG1842	Phage shock protein A
KAM471c_36700	COG0204	Acyl-transferase
KAM471c_36740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KAM471c_36760	COG0484	heat shock protein binding
KAM471c_36870	COG1289	transmembrane transporter activity
KAM471c_36880	COG1566	PFAM secretion protein HlyD family protein
KAM471c_36900	COG1566	PFAM secretion protein HlyD family protein
KAM471c_36930	COG1051	belongs to the nudix hydrolase family
KAM471c_36940	COG3150	esterase
KAM471c_36960	COG3151	Protein conserved in bacteria
KAM471c_36970	COG0494	nUDIX hydrolase
KAM471c_36980	COG1538	Outer membrane efflux protein
KAM471c_36990	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KAM471c_36990	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KAM471c_37000	COG1560	Kdo2-lipid A biosynthetic process
KAM471c_37030	COG2771	luxR family
KAM471c_37040	COG3916	Acyl-homoserine-lactone synthase
KAM471c_37060	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
KAM471c_37070	COG2213	PTS system mannitol-specific
KAM471c_37070	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM471c_37080	COG2213	PTS system mannitol-specific
KAM471c_37080	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM471c_37090	COG0246	Mannitol dehydrogenase
KAM471c_37100	COG3722	fumarate hydratase activity
KAM471c_37110	COG3263	regulation of cellular component size
KAM471c_37150	COG1671	Belongs to the UPF0178 family
KAM471c_37180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KAM471c_37190	COG0513	Belongs to the DEAD box helicase family
KAM471c_37230	COG1575	Belongs to the MenA family. Type 1 subfamily
KAM471c_37240	COG1169	isochorismate synthase
KAM471c_37250	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KAM471c_37260	COG0596	Alpha beta hydrolase
KAM471c_37270	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KAM471c_37290	COG0318	PFAM AMP-dependent synthetase and ligase
KAM471c_37300	COG3291	Pkd domain containing protein
KAM471c_37310	COG2949	membrane
KAM471c_37320	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KAM471c_37340	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KAM471c_37400	COG2873	o-acetylhomoserine
KAM471c_37420	COG1979	alcohol dehydrogenase
KAM471c_37450	COG4221	oxidoreductase activity
KAM471c_37490	COG1285	pathogenesis
KAM471c_37520	COG1368	sulfuric ester hydrolase activity
KAM471c_37530	COG1522	sequence-specific DNA binding
KAM471c_37550	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KAM471c_37570	COG1546	Belongs to the CinA family
KAM471c_37570	COG1058	Belongs to the CinA family
KAM471c_37580	COG1988	membrane-bound metal-dependent
KAM471c_37610	COG0561	phosphatase activity
KAM471c_37620	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KAM471c_37640	COG1011	Hydrolase
KAM471c_37670	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KAM471c_37680	COG0019	diaminopimelate decarboxylase activity
KAM471c_37700	COG1965	Belongs to the frataxin family
KAM471c_37710	COG0400	carboxylic ester hydrolase activity
KAM471c_37720	COG3072	Adenylate cyclase
KAM471c_37730	COG0181	hydroxymethylbilane synthase activity
KAM471c_37750	COG2959	enzyme of heme biosynthesis
KAM471c_37760	COG3071	HemY protein
KAM471c_37780	COG0312	modulator of DNA gyrase
KAM471c_37790	COG3028	Belongs to the UPF0307 family
KAM471c_37810	COG2926	Belongs to the UPF0265 family
KAM471c_37830	COG1396	sequence-specific DNA binding
KAM471c_37840	COG3135	benzoate transporter
KAM471c_37900	COG3047	cAMP biosynthetic process
KAM471c_37920	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KAM471c_37930	COG2197	response regulator
KAM471c_37990	COG3385	transposase activity
KAM471c_38050	COG5642	Protein of unknown function (DUF2384)
KAM471c_38070	COG5433	transposase activity
KAM471c_38080	COG3039	Transposase
KAM471c_38140	COG1278	Cold shock
KAM471c_38200	COG3706	GGDEF domain
KAM471c_38210	COG0347	Belongs to the P(II) protein family
KAM471c_38220	COG0004	ammonium transporteR
KAM471c_38240	COG0346	lactoylglutathione lyase activity
KAM471c_38250	COG3039	Transposase
KAM471c_38270	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KAM471c_38280	COG1074	ATP-dependent DNA helicase activity
KAM471c_38290	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KAM471c_38300	COG2259	Doxx family
KAM471c_38310	COG1741	Belongs to the pirin family
KAM471c_38330	COG0583	DNA-binding transcription factor activity
KAM471c_38380	COG1175	transmembrane transport
KAM471c_38400	COG3842	ATPase activity
KAM471c_38460	COG0456	acetyltransferase
KAM471c_38460	COG0454	-acetyltransferase
KAM471c_38470	COG0753	catalase activity
KAM471c_38510	COG0494	nUDIX hydrolase
KAM471c_38520	COG0628	permease
KAM471c_38540	COG2957	Belongs to the agmatine deiminase family
KAM471c_38570	COG2957	Belongs to the agmatine deiminase family
KAM471c_38580	COG0583	DNA-binding transcription factor activity
KAM471c_38610	COG1461	Dihydroxyacetone kinase
KAM471c_38620	COG2376	Dihydroxyacetone kinase
KAM471c_38630	COG2252	PERMEase
KAM471c_38640	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KAM471c_38650	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KAM471c_38660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KAM471c_38670	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KAM471c_38680	COG0049	tRNA binding
KAM471c_38690	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KAM471c_38720	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KAM471c_38730	COG0251	oxidation-reduction process
KAM471c_38740	COG2964	Protein conserved in bacteria
KAM471c_38750	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KAM471c_38760	COG0085	RNA polymerase activity
KAM471c_38770	COG0222	ribosome binding
KAM471c_38780	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KAM471c_38790	COG0081	regulation of translation
KAM471c_38800	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KAM471c_38810	COG0250	Participates in transcription elongation, termination and antitermination
KAM471c_38830	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KAM471c_38860	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KAM471c_38870	COG0569	domain protein
KAM471c_38880	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KAM471c_38890	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KAM471c_38900	COG3005	denitrification pathway
KAM471c_38910	COG0243	molybdopterin cofactor binding
KAM471c_38980	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KAM471c_39000	COG2204	response regulator
KAM471c_39020	COG2205	protein histidine kinase activity
KAM471c_39050	COG0516	GMP reductase activity
KAM471c_39050	COG0517	IMP dehydrogenase activity
KAM471c_39070	COG1522	sequence-specific DNA binding
KAM471c_39080	COG2502	aspartate--ammonia ligase
KAM471c_39110	COG0583	DNA-binding transcription factor activity
KAM471c_39120	COG0542	response to heat
KAM471c_39140	COG0564	pseudouridine synthase activity
KAM471c_39150	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAM471c_39160	COG3681	Belongs to the UPF0597 family
KAM471c_39170	COG2964	Protein conserved in bacteria
KAM471c_39180	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KAM471c_39190	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KAM471c_39200	COG1979	alcohol dehydrogenase
KAM471c_39210	COG2207	Transcriptional regulator
KAM471c_39220	COG3040	lipid binding
KAM471c_39260	COG0583	DNA-binding transcription factor activity
KAM471c_39290	COG0540	Belongs to the ATCase OTCase family
KAM471c_39300	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
KAM471c_39310	COG1438	arginine binding
KAM471c_39320	COG1288	antiporter activity
KAM471c_39330	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KAM471c_39410	COG3250	beta-galactosidase activity
KAM471c_39430	COG1609	Transcriptional regulator
KAM471c_39440	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KAM471c_39460	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KAM471c_39470	COG2017	converts alpha-aldose to the beta-anomer
KAM471c_39480	COG0667	Aldo Keto reductase
KAM471c_39490	COG1968	undecaprenyl-diphosphatase activity
KAM471c_39500	COG3806	Anti-sigma factor
KAM471c_39510	COG1595	DNA-templated transcription, initiation
KAM471c_39550	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KAM471c_39560	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KAM471c_39570	COG0477	Major facilitator Superfamily
KAM471c_39600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM471c_39610	COG1131	(ABC) transporter
KAM471c_39620	COG0842	Transport permease protein
KAM471c_39630	COG0842	Transport permease protein
KAM471c_39640	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KAM471c_39660	COG2116	formate transmembrane transporter activity
KAM471c_39670	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KAM471c_39670	COG1648	precorrin-2 dehydrogenase activity
KAM471c_39680	COG2239	Acts as a magnesium transporter
KAM471c_39690	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KAM471c_39700	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KAM471c_39720	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KAM471c_39740	COG0514	ATP-dependent DNA helicase (RecQ)
KAM471c_39750	COG2050	protein possibly involved in aromatic compounds catabolism
KAM471c_39770	COG2258	MOSC domain
KAM471c_39780	COG1177	transmembrane transport
KAM471c_39790	COG1176	ABC-type spermidine putrescine transport system, permease component I
KAM471c_39800	COG3842	ATPase activity
KAM471c_39850	COG0174	glutamine synthetase
KAM471c_39890	COG3045	CreA protein
KAM471c_39900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KAM471c_39910	COG0443	Heat shock 70 kDa protein
KAM471c_39940	COG0366	Alpha amylase catalytic
KAM471c_39970	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KAM471c_39980	COG0745	RESPONSE REGULATOR receiver
KAM471c_39990	COG2205	protein histidine kinase activity
KAM471c_40010	COG0281	malic enzyme
KAM471c_40020	COG0702	epimerase
KAM471c_40030	COG0254	rRNA binding
KAM471c_40040	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KAM471c_40110	COG0129	dihydroxy-acid dehydratase activity
KAM471c_40130	COG3978	acetolactate synthase activity
KAM471c_40150	COG0606	chelatase, subunit chli
KAM471c_40160	COG0204	Acyl-transferase
KAM471c_40170	COG0204	Acyl-transferase
KAM471c_40180	COG1683	Conserved Protein
KAM471c_40200	COG1335	isochorismatase
KAM471c_40220	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KAM471c_40230	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KAM471c_40250	COG3084	Protein conserved in bacteria
KAM471c_40260	COG5001	Diguanylate cyclase
KAM471c_40260	COG2203	Gaf domain
KAM471c_40260	COG3706	GGDEF domain
KAM471c_40260	COG4251	negative regulation of phosphorylation
KAM471c_40290	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KAM471c_40300	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KAM471c_40310	COG1561	YicC-like family, N-terminal region
KAM471c_40330	COG1519	Transferase
KAM471c_40340	COG0859	PFAM glycosyl transferase family 9
KAM471c_40350	COG0463	Glycosyl transferase, family 2
KAM471c_40360	COG0859	PFAM glycosyl transferase family 9
KAM471c_40370	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KAM471c_40380	COG2990	Protein conserved in bacteria
KAM471c_40390	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KAM471c_40410	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KAM471c_40420	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KAM471c_40430	COG2003	Belongs to the UPF0758 family
KAM471c_40440	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KAM471c_40450	COG0756	dUTP diphosphatase activity
KAM471c_40460	COG1309	transcriptional regulator
KAM471c_40480	COG0668	transmembrane transport
KAM471c_40500	COG0166	Belongs to the GPI family
KAM471c_40510	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KAM471c_40520	COG0583	DNA-binding transcription factor activity
KAM471c_40540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KAM471c_40540	COG1042	CoA-binding domain protein
KAM471c_40540	COG0045	succinate-CoA ligase (ADP-forming) activity
KAM471c_40550	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
KAM471c_40560	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KAM471c_40570	COG1739	Uncharacterized protein family UPF0029
KAM471c_40580	COG0006	proline dipeptidase activity
KAM471c_40590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KAM471c_40600	COG1250	3-hydroxyacyl-CoA dehydrogenase
KAM471c_40600	COG1024	Enoyl-CoA hydratase
KAM471c_40610	COG0183	Belongs to the thiolase family
KAM471c_40660	COG0425	Belongs to the sulfur carrier protein TusA family
KAM471c_40670	COG0251	oxidation-reduction process
KAM471c_40680	COG2885	chlorophyll binding
KAM471c_40710	COG1335	isochorismatase
KAM471c_40720	COG2818	Glycosylase
KAM471c_40730	COG0752	glycyl-tRNA synthetase alpha subunit
KAM471c_40740	COG0751	glycine-tRNA ligase activity
KAM471c_40780	COG4251	negative regulation of phosphorylation
KAM471c_40780	COG2203	Gaf domain
KAM471c_40780	COG3706	GGDEF domain
KAM471c_40780	COG5001	Diguanylate cyclase
KAM471c_40810	COG0814	amino acid
KAM471c_40820	COG0814	amino acid
KAM471c_40840	COG3033	Beta-eliminating lyase
KAM471c_40860	COG0348	domain, Protein
KAM471c_40880	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAM471c_40890	COG1773	rubredoxin
KAM471c_40890	COG0426	domain, Protein
KAM471c_40900	COG3604	Transcriptional regulator
KAM471c_40910	COG1609	Transcriptional regulator
KAM471c_40990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KAM471c_41020	COG2960	long-chain fatty acid transporting porin activity
KAM471c_41040	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KAM471c_41070	COG3118	belongs to the thioredoxin family
KAM471c_41080	COG0513	Belongs to the DEAD box helicase family
KAM471c_41090	COG0248	Ppx GppA phosphatase
KAM471c_41110	COG0742	ribosomal rna small subunit methyltransferase
KAM471c_41150	COG0084	hydrolase, TatD family'
KAM471c_41160	COG0805	protein transport
KAM471c_41170	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KAM471c_41180	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KAM471c_41190	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KAM471c_41200	COG3165	ubiquinone biosynthetic process from chorismate
KAM471c_41220	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KAM471c_41230	COG0402	S-adenosylhomocysteine deaminase activity
KAM471c_41250	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KAM471c_41260	COG0848	biopolymer transport protein
KAM471c_41270	COG0811	peptide transport
KAM471c_41280	COG0811	peptide transport
KAM471c_41300	COG2771	luxR family
KAM471c_41390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KAM471c_41400	COG0443	Heat shock 70 kDa protein
KAM471c_41470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KAM471c_41480	COG1349	DNA-binding transcription factor activity
KAM471c_41490	COG0745	RESPONSE REGULATOR receiver
KAM471c_41500	COG2205	protein histidine kinase activity
KAM471c_41520	COG4452	Inner membrane protein CreD
KAM471c_41530	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KAM471c_41540	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KAM471c_41550	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KAM471c_41560	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KAM471c_41570	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KAM471c_41580	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KAM471c_41590	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KAM471c_41610	COG0356	it plays a direct role in the translocation of protons across the membrane
KAM471c_41630	COG1475	DNA binding
KAM471c_41640	COG1192	Involved in chromosome partitioning
KAM471c_41650	COG0357	Ribosomal RNA small subunit methyltransferase G
KAM471c_41660	COG0445	tRNA wobble uridine modification
KAM471c_41670	COG0716	FMN binding
KAM471c_41680	COG4774	siderophore transport
KAM471c_41690	COG4615	Cyclic peptide transporter
KAM471c_41700	COG1120	ATPase activity
KAM471c_41710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KAM471c_41730	COG3550	peptidyl-serine autophosphorylation
KAM471c_41770	COG2801	Transposase and inactivated derivatives
KAM471c_41790	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KAM471c_41800	COG0706	membrane insertase activity
KAM471c_41810	COG0594	ribonuclease P activity
KAM471c_41820	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KAM471c_41830	COG1126	abc transporter atp-binding protein
KAM471c_41870	COG0789	Transcriptional regulator
KAM471c_41970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KAM471c_41990	COG0443	Heat shock 70 kDa protein
KAM471c_42150	COG5002	protein histidine kinase activity
KAM471c_42150	COG2176	DNA-directed DNA polymerase activity
KAM471c_42280	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM471c_42410	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM471c_42440	COG1192	Involved in chromosome partitioning