locus-tag	class	description
KAM497c_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KAM497c_00020	COG0592	DNA-directed DNA polymerase activity
KAM497c_00040	COG0187	DNA topoisomerase II activity
KAM497c_00060	COG2378	regulation of single-species biofilm formation
KAM497c_00070	COG0071	Belongs to the small heat shock protein (HSP20) family
KAM497c_00080	COG0071	Belongs to the small heat shock protein (HSP20) family
KAM497c_00090	COG3977	Valine--pyruvate aminotransferase
KAM497c_00120	COG2814	Major facilitator Superfamily
KAM497c_00130	COG0745	RESPONSE REGULATOR receiver
KAM497c_00140	COG2205	protein histidine kinase activity
KAM497c_00180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KAM497c_00190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM497c_00190	COG4191	Histidine kinase
KAM497c_00200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM497c_00210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM497c_00220	COG1309	transcriptional regulator
KAM497c_00240	COG0561	phosphatase activity
KAM497c_00250	COG2267	carboxylic ester hydrolase activity
KAM497c_00260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KAM497c_00270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KAM497c_00290	COG1758	RNA polymerase activity
KAM497c_00310	COG0859	PFAM glycosyl transferase family 9
KAM497c_00320	COG3642	lipopolysaccharide core region biosynthetic process
KAM497c_00400	COG0589	response to stress
KAM497c_00410	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KAM497c_00420	COG3706	GGDEF domain
KAM497c_00430	COG1528	Iron-storage protein
KAM497c_00440	COG2081	HI0933 family
KAM497c_00450	COG2223	nitrite transmembrane transporter activity
KAM497c_00460	COG1280	lysine exporter protein (LysE YggA)
KAM497c_00490	COG3039	Transposase
KAM497c_00520	COG3039	Transposase
KAM497c_00530	COG2205	protein histidine kinase activity
KAM497c_00530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM497c_00560	COG3275	phosphorelay sensor kinase activity
KAM497c_00570	COG3279	Response regulator of the LytR AlgR family
KAM497c_00580	COG2223	nitrite transmembrane transporter activity
KAM497c_00610	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KAM497c_00620	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KAM497c_00690	COG0045	succinate-CoA ligase (ADP-forming) activity
KAM497c_00690	COG1042	CoA-binding domain protein
KAM497c_00690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KAM497c_00710	COG0583	DNA-binding transcription factor activity
KAM497c_00720	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KAM497c_00730	COG0166	Belongs to the GPI family
KAM497c_00750	COG0668	transmembrane transport
KAM497c_00760	COG1309	transcriptional regulator
KAM497c_00770	COG0756	dUTP diphosphatase activity
KAM497c_00780	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KAM497c_00790	COG2003	Belongs to the UPF0758 family
KAM497c_00800	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KAM497c_00810	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KAM497c_00830	COG2990	Protein conserved in bacteria
KAM497c_00840	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KAM497c_00850	COG0859	PFAM glycosyl transferase family 9
KAM497c_00860	COG0463	Glycosyl transferase, family 2
KAM497c_00870	COG0859	PFAM glycosyl transferase family 9
KAM497c_00880	COG1519	Transferase
KAM497c_00900	COG3550	peptidyl-serine autophosphorylation
KAM497c_00910	COG3550	peptidyl-serine autophosphorylation
KAM497c_00950	COG2801	Transposase and inactivated derivatives
KAM497c_00960	COG2963	transposase activity
KAM497c_01010	COG1561	YicC-like family, N-terminal region
KAM497c_01020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KAM497c_01030	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KAM497c_01060	COG5001	Diguanylate cyclase
KAM497c_01060	COG4251	negative regulation of phosphorylation
KAM497c_01060	COG3706	GGDEF domain
KAM497c_01060	COG2203	Gaf domain
KAM497c_01070	COG3084	Protein conserved in bacteria
KAM497c_01090	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KAM497c_01100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KAM497c_01120	COG1335	isochorismatase
KAM497c_01140	COG1683	Conserved Protein
KAM497c_01150	COG0204	Acyl-transferase
KAM497c_01160	COG0204	Acyl-transferase
KAM497c_01170	COG0606	chelatase, subunit chli
KAM497c_01190	COG3978	acetolactate synthase activity
KAM497c_01210	COG0129	dihydroxy-acid dehydratase activity
KAM497c_01250	COG1309	transcriptional regulator
KAM497c_01260	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KAM497c_01270	COG0254	rRNA binding
KAM497c_01280	COG0702	epimerase
KAM497c_01290	COG0281	malic enzyme
KAM497c_01310	COG2205	protein histidine kinase activity
KAM497c_01320	COG0745	RESPONSE REGULATOR receiver
KAM497c_01330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KAM497c_01360	COG0366	Alpha amylase catalytic
KAM497c_01390	COG0443	Heat shock 70 kDa protein
KAM497c_01400	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KAM497c_01410	COG3045	CreA protein
KAM497c_01450	COG0174	glutamine synthetase
KAM497c_01490	COG3842	ATPase activity
KAM497c_01500	COG1176	ABC-type spermidine putrescine transport system, permease component I
KAM497c_01510	COG1177	transmembrane transport
KAM497c_01520	COG2258	MOSC domain
KAM497c_01540	COG2050	protein possibly involved in aromatic compounds catabolism
KAM497c_01550	COG0514	ATP-dependent DNA helicase (RecQ)
KAM497c_01570	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KAM497c_01590	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KAM497c_01600	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KAM497c_01610	COG2239	Acts as a magnesium transporter
KAM497c_01620	COG1648	precorrin-2 dehydrogenase activity
KAM497c_01620	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KAM497c_01630	COG2116	formate transmembrane transporter activity
KAM497c_01650	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KAM497c_01660	COG0842	Transport permease protein
KAM497c_01670	COG0842	Transport permease protein
KAM497c_01680	COG1131	(ABC) transporter
KAM497c_01690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM497c_01720	COG0477	Major facilitator Superfamily
KAM497c_01730	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KAM497c_01740	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KAM497c_01780	COG1595	DNA-templated transcription, initiation
KAM497c_01790	COG3806	Anti-sigma factor
KAM497c_01800	COG1968	undecaprenyl-diphosphatase activity
KAM497c_01810	COG0667	Aldo Keto reductase
KAM497c_01820	COG2017	converts alpha-aldose to the beta-anomer
KAM497c_01830	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KAM497c_01850	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KAM497c_01860	COG1609	Transcriptional regulator
KAM497c_01880	COG3250	beta-galactosidase activity
KAM497c_01960	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KAM497c_01970	COG1288	antiporter activity
KAM497c_01980	COG1438	arginine binding
KAM497c_01990	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
KAM497c_02000	COG0540	Belongs to the ATCase OTCase family
KAM497c_02030	COG0583	DNA-binding transcription factor activity
KAM497c_02070	COG3040	lipid binding
KAM497c_02080	COG2207	Transcriptional regulator
KAM497c_02090	COG1979	alcohol dehydrogenase
KAM497c_02100	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KAM497c_02110	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KAM497c_02120	COG2964	Protein conserved in bacteria
KAM497c_02130	COG3681	Belongs to the UPF0597 family
KAM497c_02140	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAM497c_02150	COG0564	pseudouridine synthase activity
KAM497c_02170	COG0542	response to heat
KAM497c_02180	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KAM497c_02190	COG2502	aspartate--ammonia ligase
KAM497c_02200	COG1522	sequence-specific DNA binding
KAM497c_02220	COG0517	IMP dehydrogenase activity
KAM497c_02220	COG0516	GMP reductase activity
KAM497c_02250	COG2205	protein histidine kinase activity
KAM497c_02270	COG2204	response regulator
KAM497c_02290	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KAM497c_02360	COG0243	molybdopterin cofactor binding
KAM497c_02370	COG3005	denitrification pathway
KAM497c_02380	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KAM497c_02390	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KAM497c_02400	COG0569	domain protein
KAM497c_02410	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KAM497c_02440	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KAM497c_02460	COG0250	Participates in transcription elongation, termination and antitermination
KAM497c_02470	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KAM497c_02480	COG0081	regulation of translation
KAM497c_02490	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KAM497c_02500	COG0222	ribosome binding
KAM497c_02510	COG0085	RNA polymerase activity
KAM497c_02520	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KAM497c_02530	COG2964	Protein conserved in bacteria
KAM497c_02540	COG0251	oxidation-reduction process
KAM497c_02550	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KAM497c_02570	COG2168	tRNA wobble position uridine thiolation
KAM497c_02580	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KAM497c_02590	COG0049	tRNA binding
KAM497c_02600	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KAM497c_02610	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KAM497c_02620	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KAM497c_02630	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KAM497c_02640	COG2252	PERMEase
KAM497c_02650	COG2376	Dihydroxyacetone kinase
KAM497c_02660	COG1461	Dihydroxyacetone kinase
KAM497c_02710	COG0628	permease
KAM497c_02720	COG0494	nUDIX hydrolase
KAM497c_02760	COG0753	catalase activity
KAM497c_02770	COG0456	acetyltransferase
KAM497c_02830	COG3842	ATPase activity
KAM497c_02850	COG1175	transmembrane transport
KAM497c_02900	COG0583	DNA-binding transcription factor activity
KAM497c_02920	COG1741	Belongs to the pirin family
KAM497c_02930	COG2259	Doxx family
KAM497c_02940	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KAM497c_02950	COG1074	ATP-dependent DNA helicase activity
KAM497c_02960	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KAM497c_03010	COG0346	lactoylglutathione lyase activity
KAM497c_03030	COG0004	ammonium transporteR
KAM497c_03040	COG0347	Belongs to the P(II) protein family
KAM497c_03050	COG3706	GGDEF domain
KAM497c_03110	COG1278	Cold shock
KAM497c_03220	COG1160	GTP binding
KAM497c_03290	COG3039	Transposase
KAM497c_03320	COG0697	spore germination
KAM497c_03470	COG3328	transposase activity
KAM497c_03480	COG5433	transposase activity
KAM497c_03500	COG5642	Protein of unknown function (DUF2384)
KAM497c_03580	COG2197	response regulator
KAM497c_03590	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KAM497c_03600	COG3047	cAMP biosynthetic process
KAM497c_03670	COG3135	benzoate transporter
KAM497c_03680	COG1396	sequence-specific DNA binding
KAM497c_03700	COG2926	Belongs to the UPF0265 family
KAM497c_03720	COG3028	Belongs to the UPF0307 family
KAM497c_03730	COG0312	modulator of DNA gyrase
KAM497c_03750	COG3071	HemY protein
KAM497c_03760	COG2959	enzyme of heme biosynthesis
KAM497c_03780	COG0181	hydroxymethylbilane synthase activity
KAM497c_03790	COG3072	Adenylate cyclase
KAM497c_03800	COG0400	carboxylic ester hydrolase activity
KAM497c_03810	COG1965	Belongs to the frataxin family
KAM497c_03830	COG0019	diaminopimelate decarboxylase activity
KAM497c_03840	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KAM497c_03870	COG1011	Hydrolase
KAM497c_03890	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KAM497c_03900	COG0561	phosphatase activity
KAM497c_03920	COG1988	membrane-bound metal-dependent
KAM497c_03930	COG1058	Belongs to the CinA family
KAM497c_03930	COG1546	Belongs to the CinA family
KAM497c_03950	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KAM497c_03970	COG1522	sequence-specific DNA binding
KAM497c_03980	COG1368	sulfuric ester hydrolase activity
KAM497c_04010	COG1285	pathogenesis
KAM497c_04050	COG4221	oxidoreductase activity
KAM497c_04080	COG1979	alcohol dehydrogenase
KAM497c_04100	COG2873	o-acetylhomoserine
KAM497c_04120	COG4533	DNA binding
KAM497c_04160	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KAM497c_04180	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KAM497c_04190	COG2949	membrane
KAM497c_04200	COG3291	Pkd domain containing protein
KAM497c_04210	COG0318	PFAM AMP-dependent synthetase and ligase
KAM497c_04230	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KAM497c_04240	COG0596	Alpha beta hydrolase
KAM497c_04250	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KAM497c_04260	COG1169	isochorismate synthase
KAM497c_04270	COG1575	Belongs to the MenA family. Type 1 subfamily
KAM497c_04310	COG0513	Belongs to the DEAD box helicase family
KAM497c_04320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KAM497c_04360	COG1671	Belongs to the UPF0178 family
KAM497c_04400	COG3263	regulation of cellular component size
KAM497c_04410	COG3722	fumarate hydratase activity
KAM497c_04420	COG0246	Mannitol dehydrogenase
KAM497c_04430	COG2213	PTS system mannitol-specific
KAM497c_04430	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM497c_04440	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
KAM497c_04460	COG3916	Acyl-homoserine-lactone synthase
KAM497c_04470	COG2771	luxR family
KAM497c_04510	COG1560	Kdo2-lipid A biosynthetic process
KAM497c_04520	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KAM497c_04520	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KAM497c_04530	COG1538	Outer membrane efflux protein
KAM497c_04540	COG0494	nUDIX hydrolase
KAM497c_04550	COG3151	Protein conserved in bacteria
KAM497c_04570	COG3150	esterase
KAM497c_04580	COG1051	belongs to the nudix hydrolase family
KAM497c_04610	COG1566	PFAM secretion protein HlyD family protein
KAM497c_04620	COG1289	transmembrane transporter activity
KAM497c_04730	COG0484	heat shock protein binding
KAM497c_04750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KAM497c_04790	COG0204	Acyl-transferase
KAM497c_04800	COG1842	Phage shock protein A
KAM497c_04830	COG2827	Endonuclease containing a URI domain
KAM497c_04840	COG2962	Rard protein
KAM497c_04850	COG1573	uracil-dna glycosylase
KAM497c_04870	COG0583	DNA-binding transcription factor activity
KAM497c_04880	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KAM497c_04890	COG1121	(ABC) transporter
KAM497c_04900	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
KAM497c_04950	COG0739	heme binding
KAM497c_04970	COG3068	Protein conserved in bacteria
KAM497c_05030	COG1522	sequence-specific DNA binding
KAM497c_05040	COG0110	maltose O-acetyltransferase activity
KAM497c_05050	COG0366	Alpha amylase catalytic
KAM497c_05060	COG1263	PTS System
KAM497c_05060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM497c_05100	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KAM497c_05110	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KAM497c_05120	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KAM497c_05130	COG2723	6-phospho-beta-galactosidase activity
KAM497c_05140	COG1447	Phosphotransferase system cellobiose-specific component IIA
KAM497c_05150	COG1940	carbohydrate kinase activity
KAM497c_05200	COG1609	Transcriptional regulator
KAM497c_05220	COG0252	asparaginase activity
KAM497c_05250	COG1803	Methylglyoxal synthase
KAM497c_05290	COG1444	tRNA N-acetyltransferase activity
KAM497c_05300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KAM497c_05300	COG1565	acr, cog1565
KAM497c_05310	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KAM497c_05320	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KAM497c_05380	COG0109	protoheme IX farnesyltransferase activity
KAM497c_05390	COG1012	belongs to the aldehyde dehydrogenase family
KAM497c_05400	COG1177	transmembrane transport
KAM497c_05410	COG1176	ABC-type spermidine putrescine transport system, permease component I
KAM497c_05420	COG3842	ATPase activity
KAM497c_05430	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KAM497c_05440	COG0583	DNA-binding transcription factor activity
KAM497c_05450	COG1757	Na H antiporter
KAM497c_05480	COG0297	glycogen (starch) synthase activity
KAM497c_05490	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KAM497c_05500	COG2813	Specifically methylates the guanine in position
KAM497c_05510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KAM497c_05520	COG2203	Gaf domain
KAM497c_05520	COG4251	negative regulation of phosphorylation
KAM497c_05520	COG5001	Diguanylate cyclase
KAM497c_05520	COG3706	GGDEF domain
KAM497c_05530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAM497c_05550	COG2995	paraquat-inducible protein a
KAM497c_05560	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KAM497c_05560	COG3008	intermembrane lipid transfer
KAM497c_05570	COG3009	Protein conserved in bacteria
KAM497c_05590	COG3240	lipase activity
KAM497c_05620	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
KAM497c_05630	COG1194	a g-specific adenine glycosylase
KAM497c_05650	COG3267	Type II secretory pathway component ExeA
KAM497c_05650	COG3409	Peptidoglycan-binding domain 1 protein
KAM497c_05660	COG0617	tRNA 3'-terminal CCA addition
KAM497c_05670	COG0306	phosphate transporter
KAM497c_05680	COG1392	Phosphate transport regulator
KAM497c_05690	COG3025	triphosphatase activity
KAM497c_05710	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KAM497c_05740	COG3541	Predicted nucleotidyltransferase
KAM497c_05750	COG4804	nuclease activity
KAM497c_05790	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KAM497c_05800	COG3133	Outer membrane lipoprotein
KAM497c_05810	COG0456	acetyltransferase
KAM497c_05840	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KAM497c_05850	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KAM497c_05870	COG3031	protein transport across the cell outer membrane
KAM497c_05890	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KAM497c_05900	COG1459	type II secretion system
KAM497c_05910	COG2165	general secretion pathway protein
KAM497c_05930	COG2165	general secretion pathway protein
KAM497c_05940	COG4795	General secretion pathway protein
KAM497c_05950	COG3156	type II secretion system protein K
KAM497c_05970	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
KAM497c_06000	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KAM497c_06030	COG1011	Hydrolase
KAM497c_06040	COG0494	nUDIX hydrolase
KAM497c_06050	COG1218	3'(2'),5'-bisphosphate nucleotidase
KAM497c_06060	COG0814	amino acid
KAM497c_06070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM497c_06100	COG0626	cystathionine gamma-synthase activity
KAM497c_06110	COG0460	homoserine dehydrogenase
KAM497c_06110	COG0527	aspartate kinase activity
KAM497c_06120	COG1346	cytolysis
KAM497c_06130	COG1380	Effector of murein hydrolase LrgA
KAM497c_06140	COG0583	DNA-binding transcription factor activity
KAM497c_06210	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KAM497c_06240	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KAM497c_06260	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KAM497c_06270	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KAM497c_06290	COG0137	argininosuccinate synthase activity
KAM497c_06300	COG0165	Argininosuccinate lyase
KAM497c_06310	COG0583	DNA-binding transcription factor activity
KAM497c_06330	COG1942	4-Oxalocrotonate Tautomerase
KAM497c_06390	COG0110	maltose O-acetyltransferase activity
KAM497c_06400	COG3174	membrane
KAM497c_06410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM497c_06420	COG1126	abc transporter atp-binding protein
KAM497c_06430	COG0765	amino acid transport
KAM497c_06440	COG0765	amino acid transport
KAM497c_06450	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KAM497c_06460	COG1505	serine-type exopeptidase activity
KAM497c_06490	COG1028	Short-chain dehydrogenase reductase Sdr
KAM497c_06500	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KAM497c_06530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KAM497c_06540	COG4991	sh3 domain protein
KAM497c_06560	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KAM497c_06570	COG1940	carbohydrate kinase activity
KAM497c_06580	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KAM497c_06590	COG0126	phosphoglycerate kinase activity
KAM497c_06610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAM497c_06640	COG4232	protein-disulfide reductase activity
KAM497c_06690	COG0354	folic acid binding
KAM497c_06700	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KAM497c_06720	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KAM497c_06730	COG1595	DNA-templated transcription, initiation
KAM497c_06740	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
KAM497c_06770	COG0481	GTPase activity
KAM497c_06780	COG0681	Belongs to the peptidase S26 family
KAM497c_06790	COG0571	ribonuclease III activity
KAM497c_06810	COG1381	Involved in DNA repair and RecF pathway recombination
KAM497c_06820	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KAM497c_06830	COG3023	N-Acetylmuramoyl-L-alanine amidase
KAM497c_06840	COG4807	Protein conserved in bacteria
KAM497c_06860	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KAM497c_06870	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KAM497c_06880	COG3956	TIGRFAM MazG family protein
KAM497c_06890	COG0504	CTP synthase activity
KAM497c_06900	COG0148	phosphopyruvate hydratase activity
KAM497c_06910	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KAM497c_06920	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KAM497c_06940	COG0585	pseudouridine synthase activity
KAM497c_06950	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KAM497c_06960	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KAM497c_06970	COG1238	metal cluster binding
KAM497c_06980	COG1388	LysM domain
KAM497c_06980	COG4942	peptidase
KAM497c_07000	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KAM497c_07010	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KAM497c_07020	COG1610	YqeY-like protein
KAM497c_07030	COG0358	DNA primase activity
KAM497c_07040	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KAM497c_07110	COG0138	bifunctional purine biosynthesis protein purh
KAM497c_07140	COG3036	rescue of stalled ribosome
KAM497c_07150	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KAM497c_07160	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KAM497c_07180	COG0673	inositol 2-dehydrogenase activity
KAM497c_07200	COG1585	Membrane protein implicated in regulation of membrane protease activity
KAM497c_07210	COG0330	HflC and HflK could
KAM497c_07220	COG1648	precorrin-2 dehydrogenase activity
KAM497c_07220	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KAM497c_07230	COG0175	sulfate reduction
KAM497c_07240	COG2895	sulfate adenylyltransferase (ATP) activity
KAM497c_07250	COG0471	metal ion transport
KAM497c_07250	COG3273	potassium ion transport
KAM497c_07260	COG0529	Catalyzes the synthesis of activated sulfate
KAM497c_07290	COG0529	Catalyzes the synthesis of activated sulfate
KAM497c_07340	COG5433	transposase activity
KAM497c_07410	COG1136	(ABC) transporter
KAM497c_07440	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
KAM497c_07470	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KAM497c_07480	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KAM497c_07490	COG0163	prenyltransferase activity
KAM497c_07520	COG1131	(ABC) transporter
KAM497c_07530	COG0842	Transport permease protein
KAM497c_07550	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KAM497c_07560	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KAM497c_07570	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KAM497c_07590	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KAM497c_07600	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KAM497c_07610	COG1489	DNA binding
KAM497c_07630	COG1643	Atp-dependent helicase
KAM497c_07640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KAM497c_07650	COG0346	lactoylglutathione lyase activity
KAM497c_07680	COG2076	Multidrug Resistance protein
KAM497c_07720	COG0671	phosphoesterase, PA-phosphatase related
KAM497c_07750	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KAM497c_07760	COG0038	chloride channel
KAM497c_07780	COG0316	Belongs to the HesB IscA family
KAM497c_07790	COG1280	lysine exporter protein (LysE YggA)
KAM497c_07800	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KAM497c_07810	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KAM497c_07830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM497c_07890	COG0745	RESPONSE REGULATOR receiver
KAM497c_07900	COG3104	oligopeptide transport
KAM497c_07910	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KAM497c_07920	COG1555	photosystem II stabilization
KAM497c_07940	COG2350	Protein conserved in bacteria
KAM497c_07950	COG2917	probably involved in intracellular septation
KAM497c_07960	COG0076	glutamate decarboxylase activity
KAM497c_07970	COG1272	protein, Hemolysin III
KAM497c_07980	COG0569	domain protein
KAM497c_07980	COG2985	domain, Protein
KAM497c_08000	COG0477	Major facilitator Superfamily
KAM497c_08010	COG0583	DNA-binding transcription factor activity
KAM497c_08020	COG3227	Zinc metalloprotease (Elastase)
KAM497c_08030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KAM497c_08040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KAM497c_08060	COG2731	YhcH YjgK YiaL family protein
KAM497c_08080	COG0668	transmembrane transport
KAM497c_08100	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KAM497c_08120	COG0789	Transcriptional regulator
KAM497c_08140	COG3039	Transposase
KAM497c_08210	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KAM497c_08230	COG0488	(ABC) transporter
KAM497c_08240	COG0516	GMP reductase activity
KAM497c_08240	COG0517	IMP dehydrogenase activity
KAM497c_08260	COG0675	Transposase, IS605 OrfB family
KAM497c_08300	COG0784	Response regulator, receiver
KAM497c_08300	COG0835	chemotaxis
KAM497c_08310	COG2755	lipolytic protein G-D-S-L family
KAM497c_08320	COG4181	ATPase activity
KAM497c_08330	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KAM497c_08340	COG1090	epimerase
KAM497c_08350	COG2200	EAL domain
KAM497c_08360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KAM497c_08370	COG4935	Belongs to the peptidase S8 family
KAM497c_08370	COG2234	aminopeptidase activity
KAM497c_08380	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KAM497c_08390	COG3171	Protein conserved in bacteria
KAM497c_08400	COG2066	Belongs to the glutaminase family
KAM497c_08410	COG2897	thiosulfate sulfurtransferase activity
KAM497c_08430	COG1132	(ABC) transporter
KAM497c_08460	COG0582	viral genome integration into host DNA
KAM497c_08500	COG3447	MASE1 domain protein
KAM497c_08500	COG5001	Diguanylate cyclase
KAM497c_08500	COG5002	protein histidine kinase activity
KAM497c_08510	COG3385	transposase activity
KAM497c_08530	COG4974	Belongs to the 'phage' integrase family
KAM497c_08590	COG3039	Transposase
KAM497c_08610	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KAM497c_08630	COG3039	Transposase
KAM497c_08690	COG1484	DNA-dependent DNA replication
KAM497c_08700	COG4584	PFAM Integrase catalytic
KAM497c_08710	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
KAM497c_08720	COG3300	MHYT domain
KAM497c_08720	COG5001	Diguanylate cyclase
KAM497c_08760	COG4628	conserved protein (DUF2132)
KAM497c_08770	COG0688	phosphatidylethanolamine metabolic process
KAM497c_08780	COG1162	GTPase activity
KAM497c_08790	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KAM497c_08800	COG1278	Cold shock
KAM497c_08820	COG0840	transmembrane signaling receptor activity
KAM497c_08830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KAM497c_08840	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KAM497c_08870	COG4584	PFAM Integrase catalytic
KAM497c_08880	COG1484	DNA-dependent DNA replication
KAM497c_08890	COG0675	Transposase, IS605 OrfB family
KAM497c_08940	COG0848	biopolymer transport protein
KAM497c_08950	COG0811	peptide transport
KAM497c_08960	COG0811	peptide transport
KAM497c_08990	COG4174	ABC transporter (Permease)
KAM497c_09000	COG4239	(ABC) transporter, permease
KAM497c_09020	COG0444	Belongs to the ABC transporter superfamily
KAM497c_09030	COG4608	Belongs to the ABC transporter superfamily
KAM497c_09050	COG2195	Cleaves the N-terminal amino acid of tripeptides
KAM497c_09060	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
KAM497c_09070	COG1073	alpha beta
KAM497c_09100	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KAM497c_09150	COG0243	molybdopterin cofactor binding
KAM497c_09160	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KAM497c_09160	COG1648	precorrin-2 dehydrogenase activity
KAM497c_09180	COG1116	anion transmembrane transporter activity
KAM497c_09180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KAM497c_09190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KAM497c_09200	COG1116	anion transmembrane transporter activity
KAM497c_09210	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KAM497c_09210	COG2146	nitrite reductase [NAD(P)H] activity
KAM497c_09220	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KAM497c_09220	COG2146	nitrite reductase [NAD(P)H] activity
KAM497c_09230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM497c_09240	COG2313	pseudouridylate synthase activity
KAM497c_09280	COG0521	Mo-molybdopterin cofactor biosynthetic process
KAM497c_09300	COG2966	Psort location CytoplasmicMembrane, score
KAM497c_09310	COG3610	response to peptide
KAM497c_09330	COG4175	Glycine betaine
KAM497c_09340	COG4176	ABC-type proline glycine betaine transport system permease component
KAM497c_09350	COG2113	Glycine betaine
KAM497c_09360	COG0175	sulfate reduction
KAM497c_09370	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KAM497c_09380	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KAM497c_09390	COG0384	phenazine biosynthesis protein PhzF
KAM497c_09400	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KAM497c_09410	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KAM497c_09430	COG0786	glutamate:sodium symporter activity
KAM497c_09440	COG0252	asparaginase activity
KAM497c_09450	COG3139	Protein of unknown function (DUF1315)
KAM497c_09490	COG0616	signal peptide processing
KAM497c_09500	COG1902	pentaerythritol trinitrate reductase activity
KAM497c_09500	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAM497c_09510	COG0778	Nitroreductase
KAM497c_09530	COG0110	maltose O-acetyltransferase activity
KAM497c_09540	COG2264	protein methyltransferase activity
KAM497c_09550	COG0604	alcohol dehydrogenase
KAM497c_09560	COG0583	DNA-binding transcription factor activity
KAM497c_09570	COG1263	PTS System
KAM497c_09570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM497c_09570	COG2190	(PTS) system
KAM497c_09580	COG4145	pantothenate transmembrane transporter activity
KAM497c_09590	COG3924	membrane
KAM497c_09600	COG0439	Biotin carboxylase
KAM497c_09610	COG0511	ligase activity, forming carbon-carbon bonds
KAM497c_09620	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KAM497c_09630	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KAM497c_09660	COG3381	protein complex oligomerization
KAM497c_09680	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KAM497c_09700	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KAM497c_09710	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KAM497c_09710	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KAM497c_09740	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KAM497c_09750	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KAM497c_09760	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KAM497c_09770	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KAM497c_09790	COG4172	Belongs to the ABC transporter superfamily
KAM497c_09810	COG0601	transmembrane transport
KAM497c_09820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAM497c_09830	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KAM497c_09840	COG0142	geranyltranstransferase activity
KAM497c_09850	COG1722	exodeoxyribonuclease VII activity
KAM497c_09860	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KAM497c_09870	COG1360	Flagellar Motor Protein
KAM497c_09900	COG1534	Rna-binding protein
KAM497c_09910	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KAM497c_09930	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KAM497c_09940	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KAM497c_09960	COG0149	triose-phosphate isomerase activity
KAM497c_09970	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KAM497c_09980	COG0779	Required for maturation of 30S ribosomal subunits
KAM497c_09990	COG0195	Participates in both transcription termination and antitermination
KAM497c_10000	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KAM497c_10010	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KAM497c_10020	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KAM497c_10030	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KAM497c_10050	COG1185	polyribonucleotide nucleotidyltransferase activity
KAM497c_10060	COG2211	Major facilitator Superfamily
KAM497c_10070	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KAM497c_10080	COG1422	Protein of unknown function (DUF1090)
KAM497c_10090	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KAM497c_10100	COG0826	peptidase U32
KAM497c_10130	COG0312	modulator of DNA gyrase
KAM497c_10140	COG0312	modulator of DNA gyrase
KAM497c_10160	COG4974	Belongs to the 'phage' integrase family
KAM497c_10170	COG1970	mechanosensitive ion channel activity
KAM497c_10190	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KAM497c_10200	COG0789	Transcriptional regulator
KAM497c_10230	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM497c_10250	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KAM497c_10260	COG0321	lipoyl(octanoyl) transferase activity
KAM497c_10270	COG2921	Belongs to the UPF0250 family
KAM497c_10280	COG1686	Belongs to the peptidase S11 family
KAM497c_10290	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KAM497c_10300	COG2951	lytic endotransglycosylase activity
KAM497c_10310	COG0772	Belongs to the SEDS family
KAM497c_10320	COG0768	penicillin binding
KAM497c_10330	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KAM497c_10340	COG0799	negative regulation of ribosome biogenesis
KAM497c_10350	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KAM497c_10380	COG0495	leucyl-tRNA aminoacylation
KAM497c_10390	COG2888	peptidyl-tyrosine sulfation
KAM497c_10400	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KAM497c_10410	COG4535	Mg2 and Co2 transporter CorC
KAM497c_10420	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KAM497c_10430	COG1702	phosphate starvation-inducible protein PhoH
KAM497c_10440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KAM497c_10450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KAM497c_10460	COG1335	isochorismatase
KAM497c_10490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAM497c_10500	COG2199	diguanylate cyclase activity
KAM497c_10520	COG2199	diguanylate cyclase activity
KAM497c_10540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KAM497c_10570	COG1464	Belongs to the NlpA lipoprotein family
KAM497c_10580	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KAM497c_10590	COG2011	ABC-type metal ion transport system permease component
KAM497c_10600	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KAM497c_10620	COG0516	GMP reductase activity
KAM497c_10630	COG4067	protein conserved in archaea
KAM497c_10630	COG0189	ligase activity
KAM497c_10670	COG0300	oxidoreductase activity
KAM497c_10690	COG1022	Amp-dependent synthetase and ligase
KAM497c_10710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KAM497c_10720	COG3214	Protein conserved in bacteria
KAM497c_10750	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
KAM497c_10760	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
KAM497c_10770	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KAM497c_10780	COG1053	succinate dehydrogenase
KAM497c_10800	COG0584	glycerophosphoryl diester phosphodiesterase
KAM497c_10810	COG3264	Mechanosensitive ion channel
KAM497c_10810	COG1511	domain protein
KAM497c_10830	COG0739	heme binding
KAM497c_10860	COG0583	DNA-binding transcription factor activity
KAM497c_10890	COG0583	DNA-binding transcription factor activity
KAM497c_10900	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KAM497c_10960	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KAM497c_10970	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KAM497c_10990	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KAM497c_11000	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KAM497c_11010	COG0546	phosphoglycolate phosphatase activity
KAM497c_11020	COG0180	Tryptophanyl-tRNA synthetase
KAM497c_11050	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KAM497c_11070	COG1012	belongs to the aldehyde dehydrogenase family
KAM497c_11090	COG0165	Argininosuccinate lyase
KAM497c_11100	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KAM497c_11130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAM497c_11150	COG0657	acetylesterase activity
KAM497c_11170	COG0490	domain, Protein
KAM497c_11170	COG0471	metal ion transport
KAM497c_11180	COG0012	GTP binding
KAM497c_11190	COG0193	aminoacyl-tRNA hydrolase activity
KAM497c_11200	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KAM497c_11210	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KAM497c_11220	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KAM497c_11230	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KAM497c_11240	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KAM497c_11250	COG2890	protein-(glutamine-N5) methyltransferase activity
KAM497c_11270	COG2912	Transglutaminase-like superfamily
KAM497c_11280	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KAM497c_11290	COG1301	dicarboxylic acid transport
KAM497c_11310	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KAM497c_11340	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KAM497c_11350	COG1115	amino acid carrier protein
KAM497c_11390	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KAM497c_11410	COG0189	ligase activity
KAM497c_11420	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KAM497c_11440	COG3091	SprT-like family
KAM497c_11460	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KAM497c_11480	COG5433	transposase activity
KAM497c_11530	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KAM497c_11540	COG0739	heme binding
KAM497c_11550	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KAM497c_11570	COG1881	PFAM PEBP family protein
KAM497c_11580	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KAM497c_11590	COG0583	DNA-binding transcription factor activity
KAM497c_11610	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KAM497c_11630	COG0583	DNA-binding transcription factor activity
KAM497c_11640	COG1028	Short-chain dehydrogenase reductase Sdr
KAM497c_11650	COG0616	signal peptide processing
KAM497c_11660	COG3724	N-succinylarginine dihydrolase activity
KAM497c_11700	COG0840	transmembrane signaling receptor activity
KAM497c_11720	COG2971	BadF BadG BcrA BcrD
KAM497c_11740	COG4608	Belongs to the ABC transporter superfamily
KAM497c_11750	COG0444	Belongs to the ABC transporter superfamily
KAM497c_11760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAM497c_11790	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KAM497c_11820	COG0640	Transcriptional regulator
KAM497c_11830	COG0798	PFAM Bile acid sodium symporter
KAM497c_11840	COG1393	Belongs to the ArsC family
KAM497c_11870	COG1677	Flagellar hook-basal body complex protein FliE
KAM497c_11890	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KAM497c_12000	COG1684	flagellar biosynthetic protein fliR
KAM497c_12020	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KAM497c_12070	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KAM497c_12080	COG0643	Histidine kinase
KAM497c_12080	COG0784	Response regulator, receiver
KAM497c_12080	COG2198	Histidine kinase
KAM497c_12090	COG2201	protein-glutamate methylesterase activity
KAM497c_12100	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KAM497c_12110	COG1360	Flagellar Motor Protein
KAM497c_12120	COG1192	Involved in chromosome partitioning
KAM497c_12140	COG0835	chemotaxis
KAM497c_12170	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KAM497c_12180	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KAM497c_12190	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KAM497c_12200	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KAM497c_12210	COG1138	Cytochrome C-type biogenesis protein
KAM497c_12220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KAM497c_12240	COG0457	Tetratricopeptide repeat
KAM497c_12270	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KAM497c_12280	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KAM497c_12280	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KAM497c_12310	COG0259	pyridoxamine-phosphate oxidase activity
KAM497c_12370	COG3153	acetyltransferase
KAM497c_12400	COG0800	Aldolase
KAM497c_12410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM497c_12510	COG0582	viral genome integration into host DNA
KAM497c_12520	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KAM497c_12530	COG2867	negative regulation of translational initiation
KAM497c_12540	COG2914	Belongs to the UPF0125 (RnfH) family
KAM497c_12550	COG0702	epimerase
KAM497c_12560	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAM497c_12570	COG1454	alcohol dehydrogenase
KAM497c_12590	COG0564	pseudouridine synthase activity
KAM497c_12660	COG1280	lysine exporter protein (LysE YggA)
KAM497c_12680	COG3263	regulation of cellular component size
KAM497c_12700	COG1876	peptidase activity
KAM497c_12710	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KAM497c_12720	COG1393	Belongs to the ArsC family
KAM497c_12740	COG3069	C4-dicarboxylate transmembrane transporter activity
KAM497c_12750	COG1473	amidohydrolase
KAM497c_12770	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KAM497c_12780	COG0017	Asparaginyl-tRNA synthetase
KAM497c_12830	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KAM497c_12840	COG0156	8-amino-7-oxononanoate synthase activity
KAM497c_12850	COG1073	alpha beta
KAM497c_12850	COG2226	methyltransferase
KAM497c_12860	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KAM497c_12870	COG0501	Belongs to the peptidase M48B family
KAM497c_12880	COG3217	Mosc domain protein beta barrel domain protein
KAM497c_12880	COG3217	Mosc domain protein beta barrel domain protein
KAM497c_12880	COG0633	Ferredoxin
KAM497c_12880	COG0633	Ferredoxin
KAM497c_12900	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KAM497c_12900	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KAM497c_12900	COG1013	pyruvate-flavodoxin oxidoreductase activity
KAM497c_12900	COG0674	pyruvate-flavodoxin oxidoreductase activity
KAM497c_12910	COG2841	Protein conserved in bacteria
KAM497c_12930	COG0534	Mate efflux family protein
KAM497c_12980	COG1454	alcohol dehydrogenase
KAM497c_13000	COG1309	transcriptional regulator
KAM497c_13030	COG0791	NLP P60 protein
KAM497c_13040	COG0583	DNA-binding transcription factor activity
KAM497c_13080	COG0500	methyltransferase
KAM497c_13090	COG4106	trans-aconitate 2-methyltransferase activity
KAM497c_13100	COG1801	Protein of unknown function DUF72
KAM497c_13110	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KAM497c_13120	COG0217	transcriptional regulatory protein
KAM497c_13130	COG2194	sulfuric ester hydrolase activity
KAM497c_13140	COG1846	Transcriptional regulator
KAM497c_13140	COG1940	carbohydrate kinase activity
KAM497c_13150	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KAM497c_13160	COG0363	glucosamine-6-phosphate deaminase activity
KAM497c_13170	COG1263	PTS System
KAM497c_13170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM497c_13170	COG2190	(PTS) system
KAM497c_13190	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KAM497c_13200	COG0735	belongs to the Fur family
KAM497c_13220	COG0716	FMN binding
KAM497c_13250	COG0596	Alpha beta hydrolase
KAM497c_13260	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
KAM497c_13270	COG0033	Phosphoglucomutase
KAM497c_13290	COG1846	Transcriptional regulator
KAM497c_13300	COG2951	lytic endotransglycosylase activity
KAM497c_13310	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KAM497c_13320	COG4136	ATPase activity
KAM497c_13340	COG4134	Bacterial extracellular solute-binding protein
KAM497c_13350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KAM497c_13360	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KAM497c_13380	COG3039	Transposase
KAM497c_13390	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM497c_13400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KAM497c_13420	COG0729	surface antigen
KAM497c_13430	COG2911	Protein conserved in bacteria
KAM497c_13450	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KAM497c_13470	COG0741	lytic transglycosylase activity
KAM497c_13500	COG1607	acyl-coa hydrolase
KAM497c_13540	COG1388	LysM domain
KAM497c_13540	COG0741	lytic transglycosylase activity
KAM497c_13550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KAM497c_13560	COG2226	methyltransferase
KAM497c_13570	COG0328	RNA-DNA hybrid ribonuclease activity
KAM497c_13580	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KAM497c_13600	COG5433	transposase activity
KAM497c_13610	COG5433	transposase activity
KAM497c_13630	COG0784	Response regulator, receiver
KAM497c_13630	COG3437	response regulator, receiver
KAM497c_13640	COG1960	acyl-CoA dehydrogenase activity
KAM497c_13650	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KAM497c_13660	COG0121	glutamine amidotransferase
KAM497c_13680	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KAM497c_13730	COG2197	response regulator
KAM497c_13740	COG3850	Histidine kinase
KAM497c_13750	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KAM497c_13760	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KAM497c_13760	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
KAM497c_13780	COG0243	molybdopterin cofactor binding
KAM497c_13790	COG0437	4 iron, 4 sulfur cluster binding
KAM497c_13800	COG0348	domain, Protein
KAM497c_13820	COG3005	denitrification pathway
KAM497c_13830	COG0521	Mo-molybdopterin cofactor biosynthetic process
KAM497c_13840	COG0315	cyclic pyranopterin monophosphate synthase activity
KAM497c_13850	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KAM497c_13860	COG0314	molybdopterin synthase activity
KAM497c_13890	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KAM497c_13900	COG2267	carboxylic ester hydrolase activity
KAM497c_13910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KAM497c_13930	COG0302	gtp cyclohydrolase
KAM497c_13940	COG0840	transmembrane signaling receptor activity
KAM497c_13950	COG0840	transmembrane signaling receptor activity
KAM497c_13960	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KAM497c_13980	COG0583	DNA-binding transcription factor activity
KAM497c_13990	COG5433	transposase activity
KAM497c_14000	COG0583	DNA-binding transcription factor activity
KAM497c_14030	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KAM497c_14060	COG2195	Cleaves the N-terminal amino acid of tripeptides
KAM497c_14070	COG1166	arginine decarboxylase activity
KAM497c_14120	COG1061	Type III restriction enzyme res subunit
KAM497c_14150	COG0675	Transposase, IS605 OrfB family
KAM497c_14170	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KAM497c_14180	COG1187	pseudouridine synthase activity
KAM497c_14190	COG2807	transmembrane transport
KAM497c_14210	COG0583	DNA-binding transcription factor activity
KAM497c_14240	COG1607	acyl-coa hydrolase
KAM497c_14250	COG2979	Protein of unknown function (DUF533)
KAM497c_14270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KAM497c_14290	COG1294	oxidase, subunit
KAM497c_14300	COG2814	Major facilitator Superfamily
KAM497c_14310	COG0656	L-ascorbic acid biosynthetic process
KAM497c_14350	COG0583	DNA-binding transcription factor activity
KAM497c_14360	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KAM497c_14370	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KAM497c_14380	COG2271	Major facilitator Superfamily
KAM497c_14390	COG5433	transposase activity
KAM497c_14400	COG2271	Major facilitator Superfamily
KAM497c_14410	COG1349	DNA-binding transcription factor activity
KAM497c_14440	COG0584	glycerophosphoryl diester phosphodiesterase
KAM497c_14450	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAM497c_14460	COG0287	Prephenate dehydrogenase
KAM497c_14460	COG1605	Chorismate mutase
KAM497c_14480	COG3085	chromosome segregation
KAM497c_14490	COG4574	serine-type endopeptidase inhibitor activity
KAM497c_14520	COG0675	Transposase, IS605 OrfB family
KAM497c_14540	COG4771	TonB-dependent receptor
KAM497c_14550	COG3083	sulfuric ester hydrolase activity
KAM497c_14560	COG3082	Protein of unknown function (DUF1414)
KAM497c_14570	COG3081	Nucleoid-associated protein
KAM497c_14590	COG1175	transmembrane transport
KAM497c_14600	COG3833	ABC-type maltose transport systems, permease component
KAM497c_14610	COG3842	ATPase activity
KAM497c_14630	COG0596	Alpha beta hydrolase
KAM497c_14660	COG4783	chaperone-mediated protein folding
KAM497c_14680	COG1393	Belongs to the ArsC family
KAM497c_14730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM497c_14740	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KAM497c_14750	COG2431	L-lysine efflux transmembrane transporter activity
KAM497c_14770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM497c_14790	COG4160	amino acid transport
KAM497c_14810	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KAM497c_14830	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAM497c_14840	COG2373	Large extracellular alpha-helical protein
KAM497c_14850	COG4953	penicillin-binding protein 1C
KAM497c_14870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KAM497c_14870	COG0301	tRNA thio-modification
KAM497c_14900	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KAM497c_14920	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KAM497c_14930	COG1334	flagellar protein FlaG
KAM497c_14990	COG2089	acid synthase
KAM497c_15020	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KAM497c_15030	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
KAM497c_15050	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KAM497c_15060	COG1086	Polysaccharide biosynthesis protein
KAM497c_15070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KAM497c_15090	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KAM497c_15140	COG0346	lactoylglutathione lyase activity
KAM497c_15150	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KAM497c_15160	COG4660	Part of a membrane complex involved in electron transport
KAM497c_15170	COG4659	FMN binding
KAM497c_15180	COG4658	electron transport chain
KAM497c_15190	COG4656	Part of a membrane complex involved in electron transport
KAM497c_15200	COG2878	Part of a membrane complex involved in electron transport
KAM497c_15210	COG4657	Part of a membrane complex involved in electron transport
KAM497c_15220	COG0675	Transposase, IS605 OrfB family
KAM497c_15230	COG0697	spore germination
KAM497c_15270	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KAM497c_15290	COG1288	antiporter activity
KAM497c_15300	COG0436	Aminotransferase
KAM497c_15330	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KAM497c_15340	COG2027	D-alanyl-D-alanine carboxypeptidase
KAM497c_15350	COG1061	Type III restriction enzyme res subunit
KAM497c_15360	COG1566	PFAM secretion protein HlyD family protein
KAM497c_15380	COG3264	Mechanosensitive ion channel
KAM497c_15380	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KAM497c_15390	COG1966	Carbon starvation protein
KAM497c_15400	COG3279	Response regulator of the LytR AlgR family
KAM497c_15410	COG3275	phosphorelay sensor kinase activity
KAM497c_15430	COG1012	belongs to the aldehyde dehydrogenase family
KAM497c_15430	COG1454	alcohol dehydrogenase
KAM497c_15440	COG2095	MarC family integral membrane protein
KAM497c_15460	COG0601	transmembrane transport
KAM497c_15470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAM497c_15480	COG0444	Belongs to the ABC transporter superfamily
KAM497c_15500	COG0861	Integral membrane protein TerC family
KAM497c_15510	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KAM497c_15530	COG1301	dicarboxylic acid transport
KAM497c_15560	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KAM497c_15590	COG0537	adenosine 5'-monophosphoramidase activity
KAM497c_15660	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAM497c_15670	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAM497c_15720	COG2354	Protein conserved in bacteria
KAM497c_15730	COG1164	Oligoendopeptidase f
KAM497c_15740	COG1164	Oligoendopeptidase f
KAM497c_15750	COG3150	esterase
KAM497c_15760	COG1252	NADH dehydrogenase
KAM497c_15770	COG0393	Putative heavy-metal-binding
KAM497c_15780	COG1368	sulfuric ester hydrolase activity
KAM497c_15800	COG0527	aspartate kinase activity
KAM497c_15810	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KAM497c_15810	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KAM497c_15820	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KAM497c_15870	COG0583	DNA-binding transcription factor activity
KAM497c_15880	COG1620	l-lactate permease
KAM497c_15890	COG0247	lactate metabolic process
KAM497c_15900	COG1139	Iron-sulfur cluster binding protein
KAM497c_15970	COG0577	efflux transmembrane transporter activity
KAM497c_15980	COG1136	(ABC) transporter
KAM497c_16020	COG2814	Major facilitator Superfamily
KAM497c_16070	COG0672	)-iron permease
KAM497c_16150	COG2308	Evidence 4 Homologs of previously reported genes of
KAM497c_16170	COG0300	oxidoreductase activity
KAM497c_16230	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KAM497c_16240	COG1537	nuclear-transcribed mRNA catabolic process, no-go decay
KAM497c_16320	COG0582	viral genome integration into host DNA
KAM497c_16330	COG0659	secondary active sulfate transmembrane transporter activity
KAM497c_16350	COG3039	Transposase
KAM497c_16390	COG4584	PFAM Integrase catalytic
KAM497c_16400	COG1484	DNA-dependent DNA replication
KAM497c_16430	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KAM497c_16440	COG3039	Transposase
KAM497c_16450	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KAM497c_16470	COG0326	Molecular chaperone. Has ATPase activity
KAM497c_16480	COG0563	adenylate kinase activity
KAM497c_16490	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KAM497c_16500	COG3788	relative of glutathione S-transferase, MAPEG superfamily
KAM497c_16510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM497c_16520	COG0840	transmembrane signaling receptor activity
KAM497c_16560	COG5001	Diguanylate cyclase
KAM497c_16560	COG3300	MHYT domain
KAM497c_16600	COG2801	Transposase and inactivated derivatives
KAM497c_16630	COG1021	2,3-dihydroxybenzoate-AMP ligase
KAM497c_16640	COG3433	isochorismatase activity
KAM497c_16640	COG1535	isochorismatase
KAM497c_16650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KAM497c_16660	COG1028	Short-chain dehydrogenase reductase Sdr
KAM497c_16680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KAM497c_16710	COG1120	ATPase activity
KAM497c_16720	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAM497c_16730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAM497c_16740	COG4771	TonB-dependent receptor
KAM497c_16820	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KAM497c_16830	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KAM497c_16840	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAM497c_16850	COG0861	Integral membrane protein TerC family
KAM497c_16880	COG1022	Amp-dependent synthetase and ligase
KAM497c_16890	COG0295	cytidine deaminase activity
KAM497c_16900	COG1346	cytolysis
KAM497c_16910	COG1380	Effector of murein hydrolase LrgA
KAM497c_16920	COG3345	alpha-galactosidase
KAM497c_16940	COG2925	Exonuclease
KAM497c_16950	COG0582	viral genome integration into host DNA
KAM497c_16970	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KAM497c_16980	COG1085	galactose-1-phosphate uridylyltransferase
KAM497c_16990	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KAM497c_17000	COG1609	Transcriptional regulator
KAM497c_17010	COG4580	involved in the transport of maltose and maltodextrins
KAM497c_17060	COG2182	Extracellular solute-binding protein
KAM497c_17070	COG1175	transmembrane transport
KAM497c_17080	COG3833	ABC-type maltose transport systems, permease component
KAM497c_17090	COG3867	Arabinogalactan endo-beta-1,4-galactanase
KAM497c_17100	COG1874	Beta-galactosidase
KAM497c_17110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM497c_17110	COG1263	PTS System
KAM497c_17130	COG0469	pyruvate kinase activity
KAM497c_17150	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KAM497c_17160	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KAM497c_17160	COG0392	lysyltransferase activity
KAM497c_17190	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KAM497c_17200	COG0436	Aminotransferase
KAM497c_17210	COG0583	DNA-binding transcription factor activity
KAM497c_17220	COG2160	L-arabinose isomerase activity
KAM497c_17240	COG1069	ribulokinase activity
KAM497c_17250	COG1879	ABC-type sugar transport system periplasmic component
KAM497c_17260	COG1129	ABC transporter
KAM497c_17270	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAM497c_17290	COG0254	rRNA binding
KAM497c_17320	COG1451	nucleotide metabolic process
KAM497c_17350	COG3069	C4-dicarboxylate transmembrane transporter activity
KAM497c_17370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAM497c_17370	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KAM497c_17380	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KAM497c_17420	COG2009	succinate dehydrogenase
KAM497c_17430	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KAM497c_17460	COG0567	Dehydrogenase, E1 component
KAM497c_17470	COG0508	dehydrogenase complex catalyzes the overall conversion of
KAM497c_17480	COG0045	succinate-CoA ligase (ADP-forming) activity
KAM497c_17490	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KAM497c_17510	COG3039	Transposase
KAM497c_17530	COG5433	transposase activity
KAM497c_17550	COG2983	Belongs to the UPF0260 family
KAM497c_17560	COG2801	Transposase and inactivated derivatives
KAM497c_17580	COG1882	Formate acetyltransferase
KAM497c_17590	COG2116	formate transmembrane transporter activity
KAM497c_17600	COG1944	ATP diphosphatase activity
KAM497c_17630	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KAM497c_17640	COG1278	Cold shock
KAM497c_17650	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KAM497c_17660	COG0542	response to heat
KAM497c_17670	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KAM497c_17680	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KAM497c_17690	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KAM497c_17700	COG3134	Outer membrane lipoprotein
KAM497c_17710	COG3706	GGDEF domain
KAM497c_17720	COG0492	ferredoxin-NADP+ reductase activity
KAM497c_17730	COG0686	Belongs to the AlaDH PNT family
KAM497c_17750	COG1674	ftsk spoiiie
KAM497c_17750	COG0531	amino acid
KAM497c_17760	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KAM497c_17770	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KAM497c_17780	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KAM497c_17790	COG1286	toxin biosynthetic process
KAM497c_17800	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KAM497c_17810	COG2723	6-phospho-beta-galactosidase activity
KAM497c_17820	COG1263	PTS System
KAM497c_17820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM497c_17830	COG1609	Transcriptional regulator
KAM497c_17850	COG4172	Belongs to the ABC transporter superfamily
KAM497c_17870	COG4171	peptide transport system, permease
KAM497c_17900	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KAM497c_17910	COG1842	Phage shock protein A
KAM497c_17940	COG3106	COG3106 Predicted ATPase
KAM497c_17950	COG3768	UPF0283 membrane protein
KAM497c_17970	COG2154	pterin-4-alpha-carbinolamine dehydratase
KAM497c_18010	COG2885	chlorophyll binding
KAM497c_18020	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KAM497c_18040	COG1570	exodeoxyribonuclease VII activity
KAM497c_18070	COG0366	Alpha amylase catalytic
KAM497c_18070	COG1874	Beta-galactosidase
KAM497c_18090	COG0517	IMP dehydrogenase activity
KAM497c_18090	COG0516	GMP reductase activity
KAM497c_18100	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KAM497c_18100	COG0519	Catalyzes the synthesis of GMP from XMP
KAM497c_18140	COG1846	Transcriptional regulator
KAM497c_18180	COG2062	phosphohistidine phosphatase, SixA
KAM497c_18200	COG0697	spore germination
KAM497c_18220	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
KAM497c_18230	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KAM497c_18250	COG4591	ABC-type transport system involved in lipoprotein release permease component
KAM497c_18260	COG1136	(ABC) transporter
KAM497c_18270	COG4591	ABC-type transport system involved in lipoprotein release permease component
KAM497c_18280	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KAM497c_18300	COG0544	peptidyl-prolyl cis-trans isomerase activity
KAM497c_18310	COG0740	serine-type endopeptidase activity
KAM497c_18320	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KAM497c_18330	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KAM497c_18340	COG0776	regulation of translation
KAM497c_18350	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KAM497c_18360	COG0488	(ABC) transporter
KAM497c_18370	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KAM497c_18380	COG3162	membrane
KAM497c_18410	COG1024	Enoyl-CoA hydratase
KAM497c_18420	COG1115	amino acid carrier protein
KAM497c_18440	COG3228	Belongs to the MtfA family
KAM497c_18450	COG1584	GPR1 FUN34 yaaH family protein
KAM497c_18500	COG1024	Enoyl-CoA hydratase
KAM497c_18510	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KAM497c_18520	COG1960	acyl-CoA dehydrogenase activity
KAM497c_18540	COG1960	acyl-CoA dehydrogenase activity
KAM497c_18550	COG1024	Enoyl-CoA hydratase
KAM497c_18560	COG1024	Enoyl-CoA hydratase
KAM497c_18580	COG1028	Short-chain dehydrogenase reductase Sdr
KAM497c_18600	COG0730	response to heat
KAM497c_18620	COG0653	protein targeting
KAM497c_18680	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAM497c_18690	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAM497c_18700	COG1129	ABC transporter
KAM497c_18710	COG1879	ABC-type sugar transport system periplasmic component
KAM497c_18720	COG0583	DNA-binding transcription factor activity
KAM497c_18750	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KAM497c_18760	COG0243	molybdopterin cofactor binding
KAM497c_18780	COG0583	DNA-binding transcription factor activity
KAM497c_18790	COG2723	6-phospho-beta-galactosidase activity
KAM497c_18810	COG0583	DNA-binding transcription factor activity
KAM497c_18840	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KAM497c_18850	COG0673	inositol 2-dehydrogenase activity
KAM497c_18860	COG0583	DNA-binding transcription factor activity
KAM497c_18880	COG1560	Kdo2-lipid A biosynthetic process
KAM497c_18890	COG1560	Kdo2-lipid A biosynthetic process
KAM497c_18920	COG0417	DNA replication proofreading
KAM497c_18930	COG0534	Mate efflux family protein
KAM497c_18950	COG0307	riboflavin synthase, alpha
KAM497c_18980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAM497c_18990	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KAM497c_19000	COG0697	spore germination
KAM497c_19010	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KAM497c_19070	COG0675	Transposase, IS605 OrfB family
KAM497c_19080	COG2996	Protein conserved in bacteria
KAM497c_19110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KAM497c_19120	COG3099	Belongs to the UPF0263 family
KAM497c_19130	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KAM497c_19140	COG2894	cell division
KAM497c_19150	COG0850	regulation of cytokinetic process
KAM497c_19160	COG3100	YcgL domain-containing protein
KAM497c_19170	COG2951	lytic endotransglycosylase activity
KAM497c_19180	COG1760	l-serine dehydratase
KAM497c_19190	COG1760	l-serine dehydratase
KAM497c_19200	COG3123	guanosine phosphorylase activity
KAM497c_19210	COG1301	dicarboxylic acid transport
KAM497c_19240	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KAM497c_19250	COG2067	long-chain fatty acid transport protein
KAM497c_19260	COG2067	long-chain fatty acid transport protein
KAM497c_19270	COG5433	transposase activity
KAM497c_19280	COG2067	long-chain fatty acid transport protein
KAM497c_19300	COG1595	DNA-templated transcription, initiation
KAM497c_19370	COG0714	Associated with various cellular activities
KAM497c_19380	COG0183	Belongs to the thiolase family
KAM497c_19390	COG1024	Enoyl-CoA hydratase
KAM497c_19390	COG1250	3-hydroxyacyl-CoA dehydrogenase
KAM497c_19410	COG4681	YaeQ
KAM497c_19470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAM497c_19510	COG3134	Outer membrane lipoprotein
KAM497c_19530	COG0675	Transposase, IS605 OrfB family
KAM497c_19540	COG0318	PFAM AMP-dependent synthetase and ligase
KAM497c_19550	COG2378	regulation of single-species biofilm formation
KAM497c_19570	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KAM497c_19570	COG0140	phosphoribosyl-ATP diphosphatase activity
KAM497c_19580	COG0107	imidazoleglycerol-phosphate synthase activity
KAM497c_19590	COG0784	Response regulator, receiver
KAM497c_19590	COG2198	Histidine kinase
KAM497c_19590	COG2205	protein histidine kinase activity
KAM497c_19600	COG2199	diguanylate cyclase activity
KAM497c_19610	COG3437	response regulator, receiver
KAM497c_19620	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KAM497c_19630	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KAM497c_19640	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KAM497c_19640	COG0131	Imidazoleglycerol-phosphate dehydratase
KAM497c_19650	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KAM497c_19660	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KAM497c_19670	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KAM497c_19690	COG1199	ATP-dependent helicase activity
KAM497c_19700	COG1214	PFAM Peptidase M22, glycoprotease
KAM497c_19720	COG0596	Alpha beta hydrolase
KAM497c_19730	COG0318	PFAM AMP-dependent synthetase and ligase
KAM497c_19740	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KAM497c_19760	COG0697	spore germination
KAM497c_19780	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KAM497c_19790	COG2832	Protein of unknown function (DUF454)
KAM497c_19800	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KAM497c_19820	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KAM497c_19830	COG0583	DNA-binding transcription factor activity
KAM497c_19850	COG3314	Sporulation integral membrane protein YlbJ
KAM497c_19860	COG2197	response regulator
KAM497c_19870	COG0517	IMP dehydrogenase activity
KAM497c_19870	COG0617	tRNA 3'-terminal CCA addition
KAM497c_19870	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KAM497c_19880	COG1643	Atp-dependent helicase
KAM497c_19900	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KAM497c_19910	COG5002	protein histidine kinase activity
KAM497c_19910	COG2205	protein histidine kinase activity
KAM497c_19910	COG0784	Response regulator, receiver
KAM497c_19960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KAM497c_19970	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
KAM497c_19980	COG0709	Synthesizes selenophosphate from selenide and ATP
KAM497c_20010	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KAM497c_20020	COG0840	transmembrane signaling receptor activity
KAM497c_20030	COG1254	Belongs to the acylphosphatase family
KAM497c_20050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM497c_20050	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM497c_20060	COG0489	protein tyrosine kinase activity
KAM497c_20070	COG0572	uridine kinase
KAM497c_20080	COG0717	Belongs to the dCTP deaminase family
KAM497c_20090	COG0306	phosphate transporter
KAM497c_20230	COG3039	Transposase
KAM497c_20240	COG1530	ribonuclease E activity
KAM497c_20250	COG0564	pseudouridine synthase activity
KAM497c_20280	COG0675	Transposase, IS605 OrfB family
KAM497c_20290	COG1399	metal-binding, possibly nucleic acid-binding protein
KAM497c_20300	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KAM497c_20310	COG0416	fatty acid biosynthetic process
KAM497c_20320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KAM497c_20340	COG1028	Short-chain dehydrogenase reductase Sdr
KAM497c_20350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KAM497c_20360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KAM497c_20370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KAM497c_20380	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KAM497c_20390	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KAM497c_20400	COG0470	DNA polymerase III
KAM497c_20410	COG0084	hydrolase, TatD family'
KAM497c_20440	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
KAM497c_20440	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KAM497c_20450	COG3008	intermembrane lipid transfer
KAM497c_20460	COG2995	paraquat-inducible protein a
KAM497c_20480	COG3141	response to X-ray
KAM497c_20500	COG1067	ATP-dependent peptidase activity
KAM497c_20510	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KAM497c_20540	COG0488	(ABC) transporter
KAM497c_20560	COG0116	Belongs to the methyltransferase superfamily
KAM497c_20560	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KAM497c_20580	COG0167	dihydroorotate dehydrogenase activity
KAM497c_20590	COG2902	Dehydrogenase
KAM497c_20610	COG0308	aminopeptidase N
KAM497c_20630	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
KAM497c_20640	COG1956	GAF domain-containing protein
KAM497c_20660	COG3278	Belongs to the heme-copper respiratory oxidase family
KAM497c_20690	COG2010	Cytochrome c
KAM497c_20710	COG2217	Heavy metal translocating P-type atpase
KAM497c_20740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KAM497c_20750	COG0589	response to stress
KAM497c_20760	COG0037	tRNA processing
KAM497c_20790	COG0625	glutathione transferase activity
KAM497c_20800	COG1869	D-ribose catabolic process
KAM497c_20810	COG1129	ABC transporter
KAM497c_20820	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAM497c_20830	COG1879	ABC-type sugar transport system periplasmic component
KAM497c_20840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM497c_20850	COG1609	Transcriptional regulator
KAM497c_20870	COG0675	Transposase, IS605 OrfB family
KAM497c_20940	COG0776	regulation of translation
KAM497c_20950	COG0072	phenylalanine-tRNA ligase activity
KAM497c_20950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM497c_20960	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KAM497c_20970	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KAM497c_20980	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KAM497c_20990	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KAM497c_21000	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KAM497c_21050	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KAM497c_21070	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KAM497c_21080	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KAM497c_21090	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KAM497c_21100	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
KAM497c_21110	COG3313	Fe-S protein
KAM497c_21120	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KAM497c_21120	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KAM497c_21120	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KAM497c_21130	COG1105	Belongs to the carbohydrate kinase PfkB family
KAM497c_21140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM497c_21140	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM497c_21150	COG1609	Transcriptional regulator
KAM497c_21160	COG0814	amino acid
KAM497c_21180	COG5654	RES domain protein
KAM497c_21190	COG0513	Belongs to the DEAD box helicase family
KAM497c_21210	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KAM497c_21220	COG2890	protein-(glutamine-N5) methyltransferase activity
KAM497c_21230	COG2840	Smr protein MutS2
KAM497c_21310	COG2824	Alkylphosphonate utilization operon protein PhnA
KAM497c_21340	COG1280	lysine exporter protein (LysE YggA)
KAM497c_21430	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KAM497c_21440	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
KAM497c_21460	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KAM497c_21470	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KAM497c_21490	COG0205	6-phosphofructokinase activity
KAM497c_21530	COG1473	amidohydrolase
KAM497c_21540	COG1011	Hydrolase
KAM497c_21550	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KAM497c_21570	COG3593	DNA synthesis involved in DNA repair
KAM497c_21600	COG0583	DNA-binding transcription factor activity
KAM497c_21610	COG0730	response to heat
KAM497c_21620	COG3148	PFAM DTW domain containing protein
KAM497c_21630	COG1181	Belongs to the D-alanine--D-alanine ligase family
KAM497c_21650	COG0386	Belongs to the glutathione peroxidase family
KAM497c_21660	COG0513	Belongs to the DEAD box helicase family
KAM497c_21730	COG2329	Antibiotic biosynthesis monooxygenase
KAM497c_21740	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KAM497c_21780	COG3243	poly(R)-hydroxyalkanoic acid synthase
KAM497c_21800	COG2501	S4 domain
KAM497c_21830	COG1132	(ABC) transporter
KAM497c_21840	COG1132	(ABC) transporter
KAM497c_21860	COG3118	belongs to the thioredoxin family
KAM497c_21870	COG0471	metal ion transport
KAM497c_21890	COG0058	SHG alpha-glucan phosphorylase activity
KAM497c_21960	COG0814	amino acid
KAM497c_21970	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KAM497c_21980	COG0514	ATP-dependent DNA helicase (RecQ)
KAM497c_21990	COG2766	serine protein kinase
KAM497c_22000	COG2718	Belongs to the UPF0229 family
KAM497c_22010	COG2719	SpoVR family
KAM497c_22020	COG2186	Transcriptional regulator
KAM497c_22030	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KAM497c_22040	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KAM497c_22050	COG0586	Pfam SNARE associated Golgi protein
KAM497c_22070	COG0556	nucleotide-excision repair
KAM497c_22090	COG0569	domain protein
KAM497c_22090	COG2985	domain, Protein
KAM497c_22100	COG1196	nuclear chromosome segregation
KAM497c_22100	COG0739	heme binding
KAM497c_22100	COG0741	lytic transglycosylase activity
KAM497c_22140	COG4565	transcriptional regulatory protein
KAM497c_22150	COG3290	protein histidine kinase activity
KAM497c_22160	COG1846	Transcriptional regulator
KAM497c_22160	COG1940	carbohydrate kinase activity
KAM497c_22170	COG0840	transmembrane signaling receptor activity
KAM497c_22180	COG3012	SEC-C Motif Domain Protein
KAM497c_22190	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KAM497c_22200	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KAM497c_22210	COG0247	lactate metabolic process
KAM497c_22250	COG3385	transposase activity
KAM497c_22270	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
KAM497c_22280	COG0437	4 iron, 4 sulfur cluster binding
KAM497c_22290	COG3301	Polysulphide reductase, NrfD
KAM497c_22300	COG1138	Cytochrome C-type biogenesis protein
KAM497c_22310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KAM497c_22320	COG3088	subunit of a heme lyase
KAM497c_22320	COG4235	cytochrome complex assembly
KAM497c_22340	COG3046	protein related to deoxyribodipyrimidine photolyase
KAM497c_22350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAM497c_22380	COG0517	IMP dehydrogenase activity
KAM497c_22380	COG0617	tRNA 3'-terminal CCA addition
KAM497c_22380	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KAM497c_22400	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KAM497c_22430	COG4774	siderophore transport
KAM497c_22440	COG3706	GGDEF domain
KAM497c_22450	COG2200	EAL domain
KAM497c_22460	COG1917	Cupin 2, conserved barrel domain protein
KAM497c_22460	COG4977	sequence-specific DNA binding
KAM497c_22470	COG0583	DNA-binding transcription factor activity
KAM497c_22480	COG2910	NAD(P)H-binding
KAM497c_22510	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KAM497c_22540	COG2226	methyltransferase
KAM497c_22660	COG3039	Transposase
KAM497c_22700	COG3039	Transposase
KAM497c_22800	COG3039	Transposase
KAM497c_22850	COG1435	thymidine kinase activity
KAM497c_22860	COG1757	Na H antiporter
KAM497c_22870	COG2916	Histone family protein nucleoid-structuring protein H-NS
KAM497c_22880	COG2096	Adenosyltransferase
KAM497c_22890	COG3530	Putative quorum-sensing-regulated virulence factor
KAM497c_22900	COG0602	queuosine metabolic process
KAM497c_22910	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KAM497c_22950	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KAM497c_22970	COG0776	regulation of translation
KAM497c_22980	COG0539	negative regulation of cytoplasmic translation
KAM497c_22990	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KAM497c_23000	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KAM497c_23060	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KAM497c_23070	COG3300	MHYT domain
KAM497c_23070	COG5001	Diguanylate cyclase
KAM497c_23090	COG0583	DNA-binding transcription factor activity
KAM497c_23100	COG0745	RESPONSE REGULATOR receiver
KAM497c_23150	COG4989	oxidoreductase activity
KAM497c_23160	COG0724	RNA recognition motif
KAM497c_23180	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
KAM497c_23200	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KAM497c_23230	COG2801	Transposase and inactivated derivatives
KAM497c_23240	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KAM497c_23250	COG1360	Flagellar Motor Protein
KAM497c_23260	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM497c_23270	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM497c_23280	COG0649	NAD binding
KAM497c_23280	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM497c_23310	COG1034	ATP synthesis coupled electron transport
KAM497c_23320	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KAM497c_23330	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM497c_23340	COG0839	Belongs to the complex I subunit 6 family
KAM497c_23350	COG0713	ATP synthesis coupled electron transport
KAM497c_23370	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAM497c_23380	COG1007	ATP synthesis coupled electron transport
KAM497c_23400	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KAM497c_23400	COG0047	phosphoribosylformylglycinamidine synthase activity
KAM497c_23410	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KAM497c_23420	COG1645	bacterial-type flagellum-dependent swarming motility
KAM497c_23430	COG1160	GTP binding
KAM497c_23440	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAM497c_23450	COG2976	Protein conserved in bacteria
KAM497c_23460	COG0124	histidyl-tRNA synthetase
KAM497c_23480	COG1426	Protein conserved in bacteria
KAM497c_23500	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KAM497c_23510	COG0105	UTP biosynthetic process
KAM497c_23520	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KAM497c_23540	COG0633	Ferredoxin
KAM497c_23550	COG0443	Heat shock 70 kDa protein
KAM497c_23560	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KAM497c_23580	COG0822	iron-sulfur transferase activity
KAM497c_23590	COG1104	cysteine desulfurase activity
KAM497c_23620	COG3154	lipid carrier protein
KAM497c_23640	COG0826	peptidase U32
KAM497c_23650	COG0826	peptidase U32
KAM497c_23680	COG2897	thiosulfate sulfurtransferase activity
KAM497c_23690	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAM497c_23700	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAM497c_23710	COG1862	Preprotein translocase
KAM497c_23720	COG0343	queuine tRNA-ribosyltransferase activity
KAM497c_23730	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KAM497c_23740	COG0517	IMP dehydrogenase activity
KAM497c_23750	COG0450	alkyl hydroperoxide reductase
KAM497c_23760	COG3634	alkyl hydroperoxide reductase activity
KAM497c_23770	COG0477	Major facilitator Superfamily
KAM497c_23790	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KAM497c_23810	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KAM497c_23810	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KAM497c_23820	COG0509	glycine decarboxylation via glycine cleavage system
KAM497c_23830	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KAM497c_23840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KAM497c_23850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KAM497c_23880	COG2814	Major facilitator Superfamily
KAM497c_23890	COG0444	Belongs to the ABC transporter superfamily
KAM497c_23900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAM497c_23910	COG0601	transmembrane transport
KAM497c_23930	COG0625	glutathione transferase activity
KAM497c_23940	COG0625	glutathione transferase activity
KAM497c_23960	COG0483	inositol monophosphate 1-phosphatase activity
KAM497c_24000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KAM497c_24010	COG2056	Na+-H+ antiporter family
KAM497c_24020	COG2814	Major facilitator Superfamily
KAM497c_24030	COG0583	DNA-binding transcription factor activity
KAM497c_24040	COG5001	Diguanylate cyclase
KAM497c_24070	COG2050	protein possibly involved in aromatic compounds catabolism
KAM497c_24090	COG0247	lactate metabolic process
KAM497c_24090	COG0277	FAD linked oxidase domain protein
KAM497c_24130	COG5433	transposase activity
KAM497c_24140	COG1253	flavin adenine dinucleotide binding
KAM497c_24150	COG1902	pentaerythritol trinitrate reductase activity
KAM497c_24170	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KAM497c_24180	COG0647	UMP catabolic process
KAM497c_24200	COG0367	asparagine synthase
KAM497c_24230	COG0625	glutathione transferase activity
KAM497c_24250	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KAM497c_24280	COG0564	pseudouridine synthase activity
KAM497c_24290	COG5001	Diguanylate cyclase
KAM497c_24300	COG0840	transmembrane signaling receptor activity
KAM497c_24310	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KAM497c_24390	COG0670	Belongs to the BI1 family
KAM497c_24400	COG1289	transmembrane transporter activity
KAM497c_24410	COG2920	part of a sulfur-relay system
KAM497c_24420	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
KAM497c_24430	COG0285	dihydrofolate synthase activity
KAM497c_24440	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KAM497c_24450	COG0101	tRNA pseudouridine synthase activity
KAM497c_24470	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KAM497c_24480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KAM497c_24500	COG1464	Belongs to the NlpA lipoprotein family
KAM497c_24540	COG1119	ATPase activity
KAM497c_24550	COG0574	Belongs to the PEP-utilizing enzyme family
KAM497c_24550	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KAM497c_24560	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KAM497c_24580	COG1113	amino acid transport
KAM497c_24690	COG1242	4 iron, 4 sulfur cluster binding
KAM497c_24700	COG0070	glutamate synthase
KAM497c_24700	COG0069	glutamate synthase activity
KAM497c_24700	COG0067	glutamate synthase
KAM497c_24710	COG0493	'glutamate synthase
KAM497c_24750	COG4104	PAAR repeat-containing protein
KAM497c_24770	COG0513	Belongs to the DEAD box helicase family
KAM497c_24820	COG3706	GGDEF domain
KAM497c_24830	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KAM497c_24840	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KAM497c_24850	COG0505	Belongs to the CarA family
KAM497c_24860	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KAM497c_24880	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KAM497c_24890	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KAM497c_24900	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KAM497c_24910	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KAM497c_24920	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAM497c_24930	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
KAM497c_24990	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KAM497c_25010	COG0023	Translation Initiation Factor
KAM497c_25020	COG2119	membrane
KAM497c_25090	COG2199	diguanylate cyclase activity
KAM497c_25090	COG2203	Gaf domain
KAM497c_25100	COG2801	Transposase and inactivated derivatives
KAM497c_25130	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KAM497c_25150	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAM497c_25160	COG2261	transglycosylase associated protein
KAM497c_25170	COG1309	transcriptional regulator
KAM497c_25180	COG0604	alcohol dehydrogenase
KAM497c_25200	COG0402	S-adenosylhomocysteine deaminase activity
KAM497c_25270	COG0582	viral genome integration into host DNA
KAM497c_25290	COG0322	excinuclease ABC activity
KAM497c_25300	COG2197	response regulator
KAM497c_25310	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KAM497c_25320	COG2835	tetraacyldisaccharide 4'-kinase activity
KAM497c_25330	COG1663	tetraacyldisaccharide 4'-kinase activity
KAM497c_25340	COG1132	(ABC) transporter
KAM497c_25350	COG2333	competence protein COMEC
KAM497c_25350	COG0658	competence protein
KAM497c_25380	COG0433	COG0433 Predicted ATPase
KAM497c_25390	COG1448	Aminotransferase
KAM497c_25440	COG1199	ATP-dependent helicase activity
KAM497c_25460	COG0123	including yeast histone deacetylase and acetoin utilization protein
KAM497c_25470	COG0477	Major facilitator Superfamily
KAM497c_25480	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KAM497c_25490	COG1785	Belongs to the alkaline phosphatase family
KAM497c_25530	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KAM497c_25540	COG3706	GGDEF domain
KAM497c_25560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM497c_25570	COG0765	amino acid transport
KAM497c_25580	COG1126	abc transporter atp-binding protein
KAM497c_25600	COG0531	amino acid
KAM497c_25630	COG1253	flavin adenine dinucleotide binding
KAM497c_25640	COG0704	Plays a role in the regulation of phosphate uptake
KAM497c_25650	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KAM497c_25660	COG0581	inorganic phosphate transmembrane transporter activity
KAM497c_25670	COG0573	inorganic phosphate transmembrane transporter activity
KAM497c_25680	COG0590	tRNA wobble adenosine to inosine editing
KAM497c_25710	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KAM497c_25750	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KAM497c_25760	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KAM497c_25770	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KAM497c_25780	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KAM497c_25830	COG2716	regulation of RNA biosynthetic process
KAM497c_25840	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KAM497c_25860	COG2239	Acts as a magnesium transporter
KAM497c_25890	COG1705	Flagellar rod assembly protein muramidase FlgJ
KAM497c_25890	COG3951	Flagellar rod assembly protein muramidase FlgJ
KAM497c_25900	COG1706	bacterial-type flagellum-dependent cell motility
KAM497c_25910	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KAM497c_25940	COG4786	Flagellar basal body rod
KAM497c_25970	COG1815	bacterial-type flagellum-dependent cell motility
KAM497c_25980	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KAM497c_25990	COG0835	chemotaxis
KAM497c_25990	COG0784	Response regulator, receiver
KAM497c_26000	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
KAM497c_26030	COG0622	Phosphoesterase
KAM497c_26040	COG0675	Transposase, IS605 OrfB family
KAM497c_26060	COG4166	transmembrane transport
KAM497c_26090	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KAM497c_26100	COG0675	Transposase, IS605 OrfB family
KAM497c_26120	COG0697	spore germination
KAM497c_26130	COG4166	transmembrane transport
KAM497c_26190	COG1278	Cold shock
KAM497c_26220	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KAM497c_26270	COG3132	Protein of unknown function, DUF480
KAM497c_26290	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAM497c_26340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KAM497c_26390	COG3039	Transposase
KAM497c_26400	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
KAM497c_26410	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KAM497c_26460	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KAM497c_26500	COG1091	dTDP-4-dehydrorhamnose reductase activity
KAM497c_26560	COG2801	Transposase and inactivated derivatives
KAM497c_26570	COG1737	Transcriptional regulator
KAM497c_26580	COG0469	pyruvate kinase activity
KAM497c_26600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM497c_26610	COG1960	acyl-CoA dehydrogenase activity
KAM497c_26630	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KAM497c_26650	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KAM497c_26670	COG0583	DNA-binding transcription factor activity
KAM497c_26700	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KAM497c_26730	COG2003	Belongs to the UPF0758 family
KAM497c_26880	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM497c_26890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM497c_26900	COG1309	transcriptional regulator
KAM497c_26930	COG1946	Acyl-CoA thioesterase
KAM497c_26960	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KAM497c_26980	COG0009	L-threonylcarbamoyladenylate synthase
KAM497c_26990	COG0613	PHP domain protein
KAM497c_27000	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KAM497c_27010	COG0512	Glutamine amidotransferase of anthranilate synthase
KAM497c_27010	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KAM497c_27020	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KAM497c_27030	COG0134	indole-3-glycerol-phosphate synthase activity
KAM497c_27030	COG0135	phosphoribosylanthranilate isomerase activity
KAM497c_27040	COG0133	tryptophan synthase activity
KAM497c_27050	COG0159	tryptophan synthase activity
KAM497c_27080	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KAM497c_27100	COG1396	sequence-specific DNA binding
KAM497c_27140	COG3550	peptidyl-serine autophosphorylation
KAM497c_27180	COG0583	DNA-binding transcription factor activity
KAM497c_27200	COG4521	taurine ABC transporter
KAM497c_27210	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KAM497c_27220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KAM497c_27230	COG2175	clavaminate synthase activity
KAM497c_27240	COG5507	3-demethylubiquinone-9 3-methyltransferase
KAM497c_27250	COG2814	Major facilitator Superfamily
KAM497c_27260	COG0109	protoheme IX farnesyltransferase activity
KAM497c_27270	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KAM497c_27280	COG1845	cytochrome c oxidase, subunit III
KAM497c_27290	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KAM497c_27300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KAM497c_27310	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KAM497c_27320	COG0583	DNA-binding transcription factor activity
KAM497c_27360	COG1846	Transcriptional regulator
KAM497c_27390	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
KAM497c_27420	COG0745	RESPONSE REGULATOR receiver
KAM497c_27440	COG0708	Exodeoxyribonuclease III
KAM497c_27460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM497c_27470	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM497c_27500	COG0095	Lipoate-protein ligase
KAM497c_27570	COG0640	Transcriptional regulator
KAM497c_27590	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAM497c_27600	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAM497c_27620	COG1285	pathogenesis
KAM497c_27680	COG0484	heat shock protein binding
KAM497c_27690	COG0443	Heat shock 70 kDa protein
KAM497c_27700	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KAM497c_27710	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KAM497c_27720	COG3706	GGDEF domain
KAM497c_27730	COG0497	DNA recombination
KAM497c_27750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM497c_27760	COG0577	efflux transmembrane transporter activity
KAM497c_27760	COG1136	(ABC) transporter
KAM497c_27770	COG1538	Outer membrane efflux protein
KAM497c_27780	COG2375	cellular response to nickel ion
KAM497c_27790	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAM497c_27800	COG2916	Histone family protein nucleoid-structuring protein H-NS
KAM497c_27810	COG0583	DNA-binding transcription factor activity
KAM497c_27820	COG3048	D-serine ammonia-lyase activity
KAM497c_27840	COG0538	isocitrate dehydrogenase activity
KAM497c_27900	COG0456	acetyltransferase
KAM497c_27910	COG1187	pseudouridine synthase activity
KAM497c_27930	COG0482	sulfurtransferase activity
KAM497c_27940	COG2915	High frequency lysogenization protein hflD homolog
KAM497c_27950	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KAM497c_27960	COG2850	peptidyl-arginine hydroxylation
KAM497c_27980	COG1196	nuclear chromosome segregation
KAM497c_27980	COG3264	Mechanosensitive ion channel
KAM497c_28060	COG0281	malic enzyme
KAM497c_28070	COG0746	molybdenum cofactor guanylyltransferase activity
KAM497c_28080	COG1763	Mo-molybdopterin cofactor biosynthetic process
KAM497c_28090	COG1289	transmembrane transporter activity
KAM497c_28100	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KAM497c_28170	COG3220	belongs to the UPF0276 family
KAM497c_28190	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KAM497c_28220	COG3039	Transposase
KAM497c_28280	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KAM497c_28290	COG0083	homoserine kinase activity
KAM497c_28310	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
KAM497c_28320	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
KAM497c_28350	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KAM497c_28370	COG0745	RESPONSE REGULATOR receiver
KAM497c_28380	COG4988	ABC transporter
KAM497c_28390	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KAM497c_28430	COG1720	tRNA m6t6A37 methyltransferase activity
KAM497c_28440	COG2801	Transposase and inactivated derivatives
KAM497c_28480	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KAM497c_28490	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KAM497c_28500	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM497c_28520	COG2190	(PTS) system
KAM497c_28530	COG3038	cytochrome b561
KAM497c_28550	COG0420	3'-5' exonuclease activity
KAM497c_28570	COG1247	-acetyltransferase
KAM497c_28580	COG2974	May be involved in recombination
KAM497c_28600	COG2801	Transposase and inactivated derivatives
KAM497c_28620	COG0405	Gamma-glutamyltransferase
KAM497c_28630	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KAM497c_28630	COG4651	solute:proton antiporter activity
KAM497c_28700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAM497c_28710	COG1917	Cupin 2, conserved barrel domain protein
KAM497c_28710	COG1396	sequence-specific DNA binding
KAM497c_28720	COG1012	belongs to the aldehyde dehydrogenase family
KAM497c_28740	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KAM497c_28860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KAM497c_28870	COG0443	Heat shock 70 kDa protein
KAM497c_28950	COG0531	amino acid
KAM497c_28970	COG0531	amino acid
KAM497c_28990	COG1283	sodium-dependent phosphate transmembrane transporter activity
KAM497c_29010	COG3384	dioxygenase
KAM497c_29020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM497c_29020	COG2205	protein histidine kinase activity
KAM497c_29040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM497c_29040	COG2205	protein histidine kinase activity
KAM497c_29060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM497c_29060	COG2198	Histidine kinase
KAM497c_29060	COG0784	Response regulator, receiver
KAM497c_29060	COG2205	protein histidine kinase activity
KAM497c_29090	COG0784	Response regulator, receiver
KAM497c_29090	COG2205	protein histidine kinase activity
KAM497c_29100	COG1376	ErfK ybiS ycfS ynhG family protein
KAM497c_29100	COG1388	LysM domain
KAM497c_29130	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
KAM497c_29140	COG0791	NLP P60 protein
KAM497c_29160	COG3118	belongs to the thioredoxin family
KAM497c_29180	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KAM497c_29190	COG0788	formyltetrahydrofolate deformylase activity
KAM497c_29240	COG1196	nuclear chromosome segregation
KAM497c_29240	COG0741	lytic transglycosylase activity
KAM497c_29240	COG0739	heme binding
KAM497c_29250	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KAM497c_29260	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KAM497c_29270	COG0673	inositol 2-dehydrogenase activity
KAM497c_29360	COG1032	radical SAM domain protein
KAM497c_29370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM497c_29390	COG3706	GGDEF domain
KAM497c_29390	COG5001	Diguanylate cyclase
KAM497c_29390	COG4251	negative regulation of phosphorylation
KAM497c_29390	COG2203	Gaf domain
KAM497c_29400	COG1752	Esterase of the alpha-beta hydrolase superfamily
KAM497c_29410	COG0733	neurotransmitter:sodium symporter activity
KAM497c_29470	COG0281	malic enzyme
KAM497c_29480	COG2207	Transcriptional regulator
KAM497c_29490	COG0534	Mate efflux family protein
KAM497c_29520	COG2233	PERMEase
KAM497c_29530	COG0095	Lipoate-protein ligase
KAM497c_29540	COG1115	amino acid carrier protein
KAM497c_29550	COG0019	diaminopimelate decarboxylase activity
KAM497c_29570	COG0678	peroxiredoxin activity
KAM497c_29580	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KAM497c_29600	COG1126	abc transporter atp-binding protein
KAM497c_29610	COG0765	amino acid transport
KAM497c_29620	COG4597	amino acid ABC transporter
KAM497c_29630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM497c_29660	COG1131	(ABC) transporter
KAM497c_29670	COG0545	Peptidyl-prolyl cis-trans isomerase
KAM497c_29690	COG1940	carbohydrate kinase activity
KAM497c_29710	COG4783	chaperone-mediated protein folding
KAM497c_29730	COG5002	protein histidine kinase activity
KAM497c_29740	COG0745	RESPONSE REGULATOR receiver
KAM497c_29750	COG0346	lactoylglutathione lyase activity
KAM497c_29760	COG3706	GGDEF domain
KAM497c_29780	COG3284	Transcriptional regulator
KAM497c_29810	COG0697	spore germination
KAM497c_29820	COG0667	Aldo Keto reductase
KAM497c_29850	COG3290	protein histidine kinase activity
KAM497c_29870	COG1566	PFAM secretion protein HlyD family protein
KAM497c_29920	COG0602	queuosine metabolic process
KAM497c_29930	COG1328	CTP reductase activity
KAM497c_29950	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KAM497c_29970	COG3115	cell septum assembly
KAM497c_29980	COG1196	nuclear chromosome segregation
KAM497c_30000	COG2860	membrane
KAM497c_30020	COG3108	Peptidase M15
KAM497c_30030	COG2989	Protein conserved in bacteria
KAM497c_30060	COG0463	Glycosyl transferase, family 2
KAM497c_30090	COG0366	Alpha amylase catalytic
KAM497c_30140	COG3335	DDE superfamily endonuclease
KAM497c_30210	COG3706	GGDEF domain
KAM497c_30220	COG0037	tRNA processing
KAM497c_30230	COG3590	peptidase
KAM497c_30250	COG0488	(ABC) transporter
KAM497c_30280	COG0531	amino acid
KAM497c_30290	COG0814	amino acid
KAM497c_30320	COG0825	malonyl-CoA metabolic process
KAM497c_30340	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KAM497c_30350	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAM497c_30360	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAM497c_30370	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KAM497c_30380	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAM497c_30410	COG0750	zinc metalloprotease
KAM497c_30420	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KAM497c_30430	COG0575	Belongs to the CDS family
KAM497c_30440	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KAM497c_30450	COG0233	cytoplasmic translational termination
KAM497c_30460	COG0528	UMP kinase activity
KAM497c_30470	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KAM497c_30480	COG0052	Belongs to the universal ribosomal protein uS2 family
KAM497c_30490	COG0024	Methionine aminopeptidase
KAM497c_30500	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KAM497c_30510	COG2171	N-acyltransferase activity
KAM497c_30530	COG1263	PTS System
KAM497c_30530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAM497c_30560	COG4580	involved in the transport of maltose and maltodextrins
KAM497c_30580	COG0564	pseudouridine synthase activity
KAM497c_30590	COG3098	single-species biofilm formation
KAM497c_30640	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
KAM497c_30660	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KAM497c_30660	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KAM497c_30690	COG1611	Belongs to the LOG family
KAM497c_30700	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KAM497c_30710	COG0473	3-isopropylmalate dehydrogenase activity
KAM497c_30730	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
KAM497c_30760	COG0583	DNA-binding transcription factor activity
KAM497c_30770	COG0840	transmembrane signaling receptor activity
KAM497c_30780	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KAM497c_30810	COG1477	protein flavinylation
KAM497c_30820	COG2871	sodium ion transport
KAM497c_30830	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM497c_30840	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM497c_30850	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM497c_30860	COG1805	sodium ion transport
KAM497c_30870	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KAM497c_30880	COG0271	Belongs to the BolA IbaG family
KAM497c_30890	COG2813	Specifically methylates the guanine in position
KAM497c_30910	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KAM497c_30930	COG2211	Major facilitator Superfamily
KAM497c_30940	COG3248	Nucleoside-binding outer membrane protein
KAM497c_30950	COG1666	GTP binding
KAM497c_30980	COG0659	secondary active sulfate transmembrane transporter activity
KAM497c_30990	COG5000	phosphorelay sensor kinase activity
KAM497c_30990	COG5002	protein histidine kinase activity
KAM497c_31000	COG0745	RESPONSE REGULATOR receiver
KAM497c_31010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM497c_31020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAM497c_31060	COG1609	Transcriptional regulator
KAM497c_31070	COG2182	Extracellular solute-binding protein
KAM497c_31080	COG0840	transmembrane signaling receptor activity
KAM497c_31090	COG1472	Belongs to the glycosyl hydrolase 3 family
KAM497c_31100	COG5297	Belongs to the glycosyl hydrolase family 6
KAM497c_31100	COG2273	Hydrolase Family 16
KAM497c_31120	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KAM497c_31130	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KAM497c_31130	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KAM497c_31140	COG2723	6-phospho-beta-galactosidase activity
KAM497c_31150	COG1447	Phosphotransferase system cellobiose-specific component IIA
KAM497c_31190	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KAM497c_31210	COG1151	hydroxylamine reductase activity
KAM497c_31220	COG0783	Belongs to the Dps family
KAM497c_31270	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KAM497c_31300	COG4221	oxidoreductase activity
KAM497c_31320	COG0415	Belongs to the DNA photolyase family
KAM497c_31330	COG0789	Transcriptional regulator
KAM497c_31340	COG3272	Protein of unknown function (DUF1722)
KAM497c_31390	COG0077	Prephenate dehydratase
KAM497c_31390	COG1605	Chorismate mutase
KAM497c_31440	COG2133	pyrroloquinoline quinone binding
KAM497c_31460	COG1349	DNA-binding transcription factor activity
KAM497c_31470	COG2084	Dehydrogenase
KAM497c_31480	COG3395	kinase activity
KAM497c_31490	COG0235	Class ii aldolase
KAM497c_31500	COG3622	Belongs to the hyi family
KAM497c_31510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KAM497c_31520	COG2610	gluconate transmembrane transporter activity
KAM497c_31560	COG0300	oxidoreductase activity
KAM497c_31610	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KAM497c_31660	COG0826	peptidase U32
KAM497c_31670	COG1280	lysine exporter protein (LysE YggA)
KAM497c_31690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KAM497c_31800	COG1566	PFAM secretion protein HlyD family protein
KAM497c_31820	COG0114	fumarate hydratase activity
KAM497c_31840	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KAM497c_31840	COG0506	proline dehydrogenase activity
KAM497c_31840	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KAM497c_31850	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KAM497c_31880	COG0737	Belongs to the 5'-nucleotidase family
KAM497c_31920	COG2204	response regulator
KAM497c_31930	COG0545	Peptidyl-prolyl cis-trans isomerase
KAM497c_31950	COG2900	Belongs to the SlyX family
KAM497c_31960	COG1047	Peptidyl-prolyl cis-trans
KAM497c_31970	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KAM497c_31990	COG0784	Response regulator, receiver
KAM497c_31990	COG0835	chemotaxis
KAM497c_32000	COG0429	hydrolase of the alpha beta-hydrolase fold
KAM497c_32010	COG3706	GGDEF domain
KAM497c_32010	COG2203	Gaf domain
KAM497c_32010	COG5001	Diguanylate cyclase
KAM497c_32010	COG4251	negative regulation of phosphorylation
KAM497c_32020	COG3089	Belongs to the UPF0270 family
KAM497c_32030	COG3954	Phosphoribulokinase
KAM497c_32060	COG1765	OsmC-like protein
KAM497c_32080	COG2226	methyltransferase
KAM497c_32100	COG2202	Pas domain
KAM497c_32100	COG2205	protein histidine kinase activity
KAM497c_32110	COG2814	Major facilitator Superfamily
KAM497c_32160	COG0748	coenzyme F420 binding
KAM497c_32170	COG3721	Heme iron utilization protein
KAM497c_32190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAM497c_32250	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KAM497c_32280	COG0741	lytic transglycosylase activity
KAM497c_32290	COG0488	(ABC) transporter
KAM497c_32310	COG2252	PERMEase
KAM497c_32330	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KAM497c_32340	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KAM497c_32350	COG3178	'Phosphotransferase
KAM497c_32360	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KAM497c_32380	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KAM497c_32390	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KAM497c_32400	COG2967	ApaG domain
KAM497c_32410	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KAM497c_32430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KAM497c_32440	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KAM497c_32450	COG3314	Sporulation integral membrane protein YlbJ
KAM497c_32460	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KAM497c_32470	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KAM497c_32480	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KAM497c_32490	COG0142	geranyltranstransferase activity
KAM497c_32500	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
KAM497c_32510	COG0330	HflC and HflK could
KAM497c_32520	COG0330	HflC and HflK could
KAM497c_32530	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KAM497c_32540	COG1923	regulation of RNA biosynthetic process
KAM497c_32550	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KAM497c_32560	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KAM497c_32580	COG0802	atpase or kinase
KAM497c_32590	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KAM497c_32590	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KAM497c_32630	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KAM497c_32640	COG2011	ABC-type metal ion transport system permease component
KAM497c_32650	COG1464	Belongs to the NlpA lipoprotein family
KAM497c_32670	COG0840	transmembrane signaling receptor activity
KAM497c_32690	COG0784	Response regulator, receiver
KAM497c_32690	COG2205	protein histidine kinase activity
KAM497c_32710	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KAM497c_32720	COG0784	Response regulator, receiver
KAM497c_32720	COG2198	Histidine kinase
KAM497c_32720	COG5002	protein histidine kinase activity
KAM497c_32760	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
KAM497c_32800	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KAM497c_32810	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
KAM497c_32820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KAM497c_32830	COG2716	regulation of RNA biosynthetic process
KAM497c_32840	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KAM497c_32850	COG3013	Belongs to the UPF0304 family
KAM497c_32870	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KAM497c_32880	COG0857	belongs to the CobB CobQ family
KAM497c_32880	COG0280	phosphate acetyltransferase
KAM497c_32890	COG0440	acetolactate synthase activity
KAM497c_32900	COG0028	Belongs to the TPP enzyme family
KAM497c_32950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KAM497c_32960	COG0473	3-isopropylmalate dehydrogenase activity
KAM497c_32970	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KAM497c_32980	COG0066	3-isopropylmalate dehydratase activity
KAM497c_33010	COG4143	(ABC) transporter
KAM497c_33020	COG1178	ABC-type Fe3 transport system permease component
KAM497c_33030	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
KAM497c_33040	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KAM497c_33060	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KAM497c_33140	COG2205	protein histidine kinase activity
KAM497c_33150	COG0745	RESPONSE REGULATOR receiver
KAM497c_33160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAM497c_33170	COG0577	efflux transmembrane transporter activity
KAM497c_33170	COG1136	(ABC) transporter
KAM497c_33200	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
KAM497c_33270	COG2199	diguanylate cyclase activity
KAM497c_33270	COG2203	Gaf domain
KAM497c_33280	COG0513	Belongs to the DEAD box helicase family
KAM497c_33300	COG1917	Cupin 2, conserved barrel domain protein
KAM497c_33300	COG2207	Transcriptional regulator
KAM497c_33380	COG0154	amidase activity
KAM497c_33390	COG2957	Belongs to the agmatine deiminase family
KAM497c_33420	COG1902	pentaerythritol trinitrate reductase activity
KAM497c_33430	COG0456	acetyltransferase
KAM497c_33480	COG5002	protein histidine kinase activity
KAM497c_33480	COG5001	Diguanylate cyclase
KAM497c_33500	COG2425	protein containing a von Willebrand factor type A (vWA) domain
KAM497c_33540	COG0456	acetyltransferase
KAM497c_33560	COG1022	Amp-dependent synthetase and ligase
KAM497c_33600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KAM497c_33630	COG0733	neurotransmitter:sodium symporter activity
KAM497c_33640	COG0733	neurotransmitter:sodium symporter activity
KAM497c_33670	COG0561	phosphatase activity
KAM497c_33730	COG1846	Transcriptional regulator
KAM497c_33740	COG2130	NADP-dependent
KAM497c_33800	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KAM497c_33810	COG1640	4-alpha-glucanotransferase
KAM497c_33820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KAM497c_33830	COG0676	glucose-6-phosphate 1-epimerase activity
KAM497c_33840	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KAM497c_33850	COG0840	transmembrane signaling receptor activity
KAM497c_33860	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
KAM497c_33870	COG2885	chlorophyll binding
KAM497c_33880	COG0823	Involved in the tonB-independent uptake of proteins
KAM497c_33910	COG0811	peptide transport
KAM497c_33920	COG0824	Thioesterase
KAM497c_33930	COG3790	cyd operon protein YbgE
KAM497c_33940	COG1294	oxidase, subunit
KAM497c_33950	COG1271	oxidase subunit
KAM497c_33960	COG2255	four-way junction helicase activity
KAM497c_33970	COG0632	four-way junction helicase activity
KAM497c_33990	COG0442	prolyl-tRNA aminoacylation
KAM497c_34000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KAM497c_34010	COG4221	oxidoreductase activity
KAM497c_34040	COG1024	Enoyl-CoA hydratase
KAM497c_34070	COG4166	transmembrane transport
KAM497c_34100	COG0513	Belongs to the DEAD box helicase family
KAM497c_34170	COG0457	Tetratricopeptide repeat
KAM497c_34170	COG3118	belongs to the thioredoxin family
KAM497c_34180	COG3118	belongs to the thioredoxin family
KAM497c_34180	COG0457	Tetratricopeptide repeat
KAM497c_34180	COG3118	belongs to the thioredoxin family
KAM497c_34180	COG0457	Tetratricopeptide repeat
KAM497c_34190	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KAM497c_34200	COG1215	transferase activity, transferring glycosyl groups
KAM497c_34210	COG1215	transferase activity, transferring glycosyl groups
KAM497c_34250	COG2194	sulfuric ester hydrolase activity
KAM497c_34260	COG2194	sulfuric ester hydrolase activity
KAM497c_34270	COG1448	Aminotransferase
KAM497c_34300	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KAM497c_34310	COG1328	CTP reductase activity
KAM497c_34360	COG0840	transmembrane signaling receptor activity
KAM497c_34370	COG3397	chitin binding
KAM497c_34380	COG0583	DNA-binding transcription factor activity
KAM497c_34390	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KAM497c_34400	COG4208	sulfate ABC transporter
KAM497c_34410	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KAM497c_34430	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KAM497c_34440	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KAM497c_34450	COG0564	pseudouridine synthase activity
KAM497c_34490	COG0459	protein refolding
KAM497c_34500	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KAM497c_34520	COG0534	Mate efflux family protein
KAM497c_34530	COG3030	protein affecting phage T7 exclusion by the F plasmid
KAM497c_34540	COG1027	Aspartate ammonia-lyase
KAM497c_34550	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KAM497c_34560	COG2918	glutathione biosynthetic process
KAM497c_34570	COG0612	Peptidase, M16
KAM497c_34580	COG1238	metal cluster binding
KAM497c_34660	COG0359	binds to the 23S rRNA
KAM497c_34670	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KAM497c_34680	COG0360	Binds together with S18 to 16S ribosomal RNA
KAM497c_34690	COG1914	H( )-stimulated, divalent metal cation uptake system
KAM497c_34720	COG2153	protein acetylation
KAM497c_34740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KAM497c_34750	COG0557	exoribonuclease II activity
KAM497c_34760	COG3706	GGDEF domain
KAM497c_34770	COG1854	S-ribosylhomocysteine lyase activity
KAM497c_34800	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KAM497c_34800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KAM497c_34840	COG3039	Transposase
KAM497c_34860	COG3039	Transposase
KAM497c_34920	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KAM497c_34930	COG1047	Peptidyl-prolyl cis-trans
KAM497c_34940	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KAM497c_34950	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KAM497c_34960	COG0196	riboflavin kinase activity
KAM497c_34970	COG0728	peptidoglycan biosynthetic process
KAM497c_34980	COG0268	Binds directly to 16S ribosomal RNA
KAM497c_34990	COG0640	Transcriptional regulator
KAM497c_35000	COG0583	DNA-binding transcription factor activity
KAM497c_35020	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KAM497c_35030	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KAM497c_35040	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KAM497c_35060	COG1051	belongs to the nudix hydrolase family
KAM497c_35090	COG0335	large ribosomal subunit rRNA binding
KAM497c_35100	COG0336	Belongs to the RNA methyltransferase TrmD family
KAM497c_35110	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KAM497c_35120	COG0228	four-way junction DNA binding
KAM497c_35130	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KAM497c_35140	COG4137	Cytochrome C assembly protein
KAM497c_35150	COG4536	flavin adenine dinucleotide binding
KAM497c_35170	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KAM497c_35170	COG1017	nitric oxide dioxygenase activity
KAM497c_35180	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
KAM497c_35200	COG0039	L-malate dehydrogenase activity
KAM497c_35210	COG4160	amino acid transport
KAM497c_35220	COG4215	(ABC) transporter
KAM497c_35230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAM497c_35240	COG1126	abc transporter atp-binding protein
KAM497c_35250	COG1438	arginine binding
KAM497c_35260	COG2837	iron assimilation
KAM497c_35270	COG3842	ATPase activity
KAM497c_35300	COG0347	Belongs to the P(II) protein family
KAM497c_35330	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KAM497c_35340	COG0583	DNA-binding transcription factor activity
KAM497c_35370	COG1929	Belongs to the glycerate kinase type-1 family
KAM497c_35380	COG2610	gluconate transmembrane transporter activity
KAM497c_35390	COG3835	regulator
KAM497c_35400	COG3112	Uncharacterised protein family (UPF0231)
KAM497c_35440	COG1872	DUF167
KAM497c_35450	COG0762	integral membrane protein
KAM497c_35460	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KAM497c_35470	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KAM497c_35500	COG3022	response to hydroperoxide
KAM497c_35510	COG0513	Belongs to the DEAD box helicase family
KAM497c_35520	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KAM497c_35560	COG0735	belongs to the Fur family
KAM497c_35570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KAM497c_35600	COG0776	regulation of translation
KAM497c_35610	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
KAM497c_35630	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KAM497c_35660	COG0560	Phosphoserine phosphatase
KAM497c_35680	COG5002	protein histidine kinase activity
KAM497c_35680	COG5001	Diguanylate cyclase
KAM497c_35680	COG3447	MASE1 domain protein
KAM497c_35700	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KAM497c_35710	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KAM497c_35720	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KAM497c_35740	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KAM497c_35750	COG0084	hydrolase, TatD family'
KAM497c_35760	COG2165	general secretion pathway protein
KAM497c_35790	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KAM497c_35800	COG0004	ammonium transporteR
KAM497c_35820	COG3039	Transposase
KAM497c_35910	COG2801	Transposase and inactivated derivatives
KAM497c_35940	COG4974	Belongs to the 'phage' integrase family
KAM497c_35960	COG0795	lipopolysaccharide-transporting ATPase activity
KAM497c_35970	COG0795	lipopolysaccharide-transporting ATPase activity
KAM497c_35980	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KAM497c_35990	COG2927	DNA polymerase III (CHI subunit)
KAM497c_36000	COG0525	valine-tRNA ligase activity
KAM497c_36010	COG1253	flavin adenine dinucleotide binding
KAM497c_36020	COG0586	Pfam SNARE associated Golgi protein
KAM497c_36030	COG1686	Belongs to the peptidase S11 family
KAM497c_36040	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KAM497c_36050	COG0527	aspartate kinase activity
KAM497c_36060	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KAM497c_36070	COG2137	regulation of response to DNA damage stimulus
KAM497c_36080	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KAM497c_36090	COG1546	Belongs to the CinA family
KAM497c_36110	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KAM497c_36160	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KAM497c_36170	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KAM497c_36200	COG0477	Major facilitator Superfamily
KAM497c_36220	COG0523	cobalamin synthesis protein
KAM497c_36240	COG1280	lysine exporter protein (LysE YggA)
KAM497c_36260	COG2200	EAL domain
KAM497c_36270	COG1049	propionate catabolic process, 2-methylcitrate cycle
KAM497c_36280	COG1752	Esterase of the alpha-beta hydrolase superfamily
KAM497c_36290	COG0840	transmembrane signaling receptor activity
KAM497c_36300	COG0840	transmembrane signaling receptor activity
KAM497c_36320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KAM497c_36330	COG0508	dehydrogenase complex catalyzes the overall conversion of
KAM497c_36340	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KAM497c_36350	COG2186	Transcriptional regulator
KAM497c_36390	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KAM497c_36400	COG1459	type II secretion system
KAM497c_36410	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KAM497c_36430	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
KAM497c_36440	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KAM497c_36450	COG0494	nUDIX hydrolase
KAM497c_36470	COG0653	protein targeting
KAM497c_36490	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KAM497c_36500	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KAM497c_36510	COG0849	cell division
KAM497c_36520	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KAM497c_36530	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KAM497c_36540	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KAM497c_36550	COG0772	Belongs to the SEDS family
KAM497c_36560	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KAM497c_36570	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KAM497c_36580	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KAM497c_36590	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KAM497c_36600	COG0768	penicillin binding
KAM497c_36610	COG3116	cell division
KAM497c_36620	COG0275	rRNA processing
KAM497c_36630	COG2001	Belongs to the MraZ family
KAM497c_36640	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KAM497c_36650	COG3107	peptidoglycan biosynthetic process
KAM497c_36660	COG0792	nuclease activity
KAM497c_36670	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KAM497c_36680	COG2823	Periplasmic or secreted lipoprotein
KAM497c_36690	COG2969	positive regulation of protein catabolic process
KAM497c_36700	COG0625	glutathione transferase activity
KAM497c_36710	COG2857	Cytochrome c1
KAM497c_36720	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KAM497c_36730	COG0723	plastoquinol--plastocyanin reductase activity
KAM497c_36750	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KAM497c_36760	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KAM497c_36770	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KAM497c_36790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KAM497c_36800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KAM497c_36860	COG3964	amidohydrolase
KAM497c_36900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM497c_36910	COG1660	Displays ATPase and GTPase activities
KAM497c_36920	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KAM497c_36960	COG4804	nuclease activity
KAM497c_36970	COG3541	Predicted nucleotidyltransferase
KAM497c_36990	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KAM497c_37010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAM497c_37030	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KAM497c_37040	COG1137	ATPase activity
KAM497c_37050	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KAM497c_37070	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KAM497c_37080	COG0517	IMP dehydrogenase activity
KAM497c_37080	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KAM497c_37090	COG1127	ABC transporter
KAM497c_37100	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KAM497c_37110	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KAM497c_37120	COG2854	intermembrane phospholipid transfer
KAM497c_37140	COG5007	Belongs to the BolA IbaG family
KAM497c_37150	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KAM497c_37170	COG1494	fructose-1,6-bisphosphatase
KAM497c_37190	COG2226	methyltransferase
KAM497c_37260	COG1733	regulation of RNA biosynthetic process
KAM497c_37300	COG3932	Exopolysaccharide synthesis, ExoD
KAM497c_37390	COG2801	Transposase and inactivated derivatives
KAM497c_37400	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KAM497c_37410	COG2022	thiamine diphosphate biosynthetic process
KAM497c_37430	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KAM497c_37440	COG0352	thiamine-phosphate diphosphorylase activity
KAM497c_37450	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KAM497c_37480	COG0745	RESPONSE REGULATOR receiver
KAM497c_37490	COG0642	Histidine kinase
KAM497c_37500	COG0189	ligase activity
KAM497c_37570	COG2321	neutral zinc metallopeptidase
KAM497c_37590	COG0477	Major facilitator Superfamily
KAM497c_37620	COG0312	modulator of DNA gyrase
KAM497c_37630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KAM497c_37640	COG3164	Protein of unknown function
KAM497c_37650	COG1530	ribonuclease E activity
KAM497c_37660	COG0424	maF-like protein
KAM497c_37670	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KAM497c_37680	COG1792	Involved in formation and maintenance of cell shape
KAM497c_37690	COG1077	Cell shape determining protein MreB Mrl
KAM497c_37750	COG4968	Prepilin-type N-terminal cleavage methylation domain
KAM497c_37760	COG4969	Belongs to the N-Me-Phe pilin family
KAM497c_37770	COG2165	general secretion pathway protein
KAM497c_37790	COG1459	type II secretion system
KAM497c_37800	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KAM497c_37900	COG2200	EAL domain
KAM497c_37910	COG0387	Pfam Sodium calcium exchanger
KAM497c_37930	COG2986	histidine ammonia-lyase
KAM497c_37940	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KAM497c_37950	COG0010	Belongs to the arginase family
KAM497c_37960	COG1228	amidohydrolase
KAM497c_37970	COG2188	Transcriptional regulator
KAM497c_37980	COG0288	reversible hydration of carbon dioxide
KAM497c_38000	COG2177	Part of the ABC transporter FtsEX involved in
KAM497c_38010	COG2884	Cell division ATP-binding protein ftsE
KAM497c_38020	COG0552	protein localization to endoplasmic reticulum
KAM497c_38030	COG0742	ribosomal rna small subunit methyltransferase
KAM497c_38080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KAM497c_38100	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KAM497c_38120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KAM497c_38140	COG2095	MarC family integral membrane protein
KAM497c_38160	COG1301	dicarboxylic acid transport
KAM497c_38180	COG0583	DNA-binding transcription factor activity
KAM497c_38210	COG3714	YhhN family
KAM497c_38250	COG1770	oligopeptidase
KAM497c_38280	COG4221	oxidoreductase activity
KAM497c_38290	COG0583	DNA-binding transcription factor activity
KAM497c_38300	COG2249	NAD(P)H dehydrogenase (quinone) activity
KAM497c_38360	COG0203	ribosomal protein L17
KAM497c_38370	COG0202	RNA polymerase activity
KAM497c_38380	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KAM497c_38390	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KAM497c_38400	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KAM497c_38410	COG0201	protein transport
KAM497c_38420	COG0200	Binds to the 23S rRNA
KAM497c_38430	COG1841	ribosomal large subunit assembly
KAM497c_38440	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KAM497c_38450	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KAM497c_38460	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KAM497c_38470	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KAM497c_38480	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KAM497c_38490	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KAM497c_38500	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KAM497c_38510	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KAM497c_38520	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KAM497c_38530	COG0255	Belongs to the universal ribosomal protein uL29 family
KAM497c_38540	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KAM497c_38550	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KAM497c_38560	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KAM497c_38570	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KAM497c_38580	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KAM497c_38590	COG0089	rRNA binding
KAM497c_38600	COG0088	Forms part of the polypeptide exit tunnel
KAM497c_38610	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KAM497c_38620	COG0051	transcription antitermination factor activity, RNA binding
KAM497c_38640	COG2205	protein histidine kinase activity
KAM497c_38660	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KAM497c_38670	COG2183	response to ionizing radiation
KAM497c_38700	COG0596	Alpha beta hydrolase
KAM497c_38710	COG1040	competence protein
KAM497c_38720	COG0316	Belongs to the HesB IscA family
KAM497c_38720	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KAM497c_38730	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KAM497c_38740	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KAM497c_38750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KAM497c_38760	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KAM497c_38770	COG4942	peptidase
KAM497c_38790	COG1609	Transcriptional regulator
KAM497c_38820	COG0800	Aldolase
KAM497c_38830	COG0129	dihydroxy-acid dehydratase activity
KAM497c_38840	COG3265	gluconokinase activity
KAM497c_38850	COG2610	gluconate transmembrane transporter activity
KAM497c_38860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KAM497c_38870	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KAM497c_38890	COG0456	acetyltransferase
KAM497c_38920	COG1490	D-aminoacyl-tRNA deacylase activity
KAM497c_38930	COG1295	ribonuclease BN
KAM497c_38940	COG1217	gtp-binding protein TYPA
KAM497c_38950	COG0174	glutamine synthetase
KAM497c_38970	COG3852	Histidine kinase
KAM497c_38990	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KAM497c_39000	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KAM497c_39020	COG3078	GTPase activator activity
KAM497c_39040	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KAM497c_39050	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KAM497c_39060	COG0408	coproporphyrinogen oxidase activity
KAM497c_39070	COG0009	L-threonylcarbamoyladenylate synthase
KAM497c_39080	COG0551	DNA topoisomerase type I activity
KAM497c_39090	COG2922	Belongs to the Smg family
KAM497c_39100	COG0758	DNA mediated transformation
KAM497c_39120	COG0242	peptide deformylase activity
KAM497c_39130	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KAM497c_39140	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KAM497c_39140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KAM497c_39150	COG0569	domain protein
KAM497c_39160	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KAM497c_39170	COG1322	Protein conserved in bacteria
KAM497c_39210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAM497c_39230	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KAM497c_39230	COG0519	Catalyzes the synthesis of GMP from XMP
KAM497c_39250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KAM497c_39260	COG1396	sequence-specific DNA binding
KAM497c_39270	COG1012	belongs to the aldehyde dehydrogenase family
KAM497c_39290	COG2962	Rard protein
KAM497c_39310	COG1280	lysine exporter protein (LysE YggA)
KAM497c_39410	COG0583	DNA-binding transcription factor activity
KAM497c_39440	COG1943	Transposase
KAM497c_39470	COG0210	DNA helicase
KAM497c_39500	COG1744	ABC transporter substrate-binding protein PnrA-like
KAM497c_39510	COG3845	ABC transporter
KAM497c_39520	COG4603	Belongs to the binding-protein-dependent transport system permease family
KAM497c_39540	COG1079	Belongs to the binding-protein-dependent transport system permease family
KAM497c_39560	COG0583	DNA-binding transcription factor activity
KAM497c_39610	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KAM497c_39620	COG0385	Bile acid
KAM497c_39630	COG0531	amino acid
KAM497c_39640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAM497c_39650	COG0531	amino acid
KAM497c_39660	COG2731	YhcH YjgK YiaL family protein
KAM497c_39670	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KAM497c_39700	COG4584	PFAM Integrase catalytic
KAM497c_39710	COG1484	DNA-dependent DNA replication
KAM497c_39820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KAM497c_39830	COG0443	Heat shock 70 kDa protein
KAM497c_39910	COG3250	beta-galactosidase activity
KAM497c_39920	COG1609	Transcriptional regulator
KAM497c_39930	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
KAM497c_39940	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KAM497c_39950	COG1739	Uncharacterized protein family UPF0029
KAM497c_39960	COG0006	proline dipeptidase activity
KAM497c_39970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KAM497c_39980	COG1024	Enoyl-CoA hydratase
KAM497c_39980	COG1250	3-hydroxyacyl-CoA dehydrogenase
KAM497c_39990	COG0183	Belongs to the thiolase family
KAM497c_40040	COG0425	Belongs to the sulfur carrier protein TusA family
KAM497c_40050	COG0251	oxidation-reduction process
KAM497c_40060	COG2885	chlorophyll binding
KAM497c_40080	COG1335	isochorismatase
KAM497c_40090	COG2818	Glycosylase
KAM497c_40100	COG0752	glycyl-tRNA synthetase alpha subunit
KAM497c_40110	COG0751	glycine-tRNA ligase activity
KAM497c_40140	COG2203	Gaf domain
KAM497c_40140	COG3706	GGDEF domain
KAM497c_40140	COG5001	Diguanylate cyclase
KAM497c_40140	COG4251	negative regulation of phosphorylation
KAM497c_40170	COG0814	amino acid
KAM497c_40180	COG0814	amino acid
KAM497c_40190	COG3033	Beta-eliminating lyase
KAM497c_40200	COG0348	domain, Protein
KAM497c_40220	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAM497c_40230	COG0426	domain, Protein
KAM497c_40230	COG1773	rubredoxin
KAM497c_40240	COG3604	Transcriptional regulator
KAM497c_40250	COG1609	Transcriptional regulator
KAM497c_40330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KAM497c_40360	COG2960	long-chain fatty acid transporting porin activity
KAM497c_40380	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KAM497c_40410	COG3118	belongs to the thioredoxin family
KAM497c_40420	COG0513	Belongs to the DEAD box helicase family
KAM497c_40430	COG0248	Ppx GppA phosphatase
KAM497c_40450	COG0742	ribosomal rna small subunit methyltransferase
KAM497c_40490	COG0084	hydrolase, TatD family'
KAM497c_40500	COG0805	protein transport
KAM497c_40510	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KAM497c_40520	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KAM497c_40530	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KAM497c_40540	COG3165	ubiquinone biosynthetic process from chorismate
KAM497c_40560	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KAM497c_40570	COG0402	S-adenosylhomocysteine deaminase activity
KAM497c_40580	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KAM497c_40590	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KAM497c_40590	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KAM497c_40600	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
KAM497c_40610	COG3074	FtsZ-dependent cytokinesis
KAM497c_40630	COG1045	serine acetyltransferase
KAM497c_40650	COG0745	RESPONSE REGULATOR receiver
KAM497c_40660	COG2205	protein histidine kinase activity
KAM497c_40670	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KAM497c_40680	COG0534	Mate efflux family protein
KAM497c_40730	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KAM497c_40740	COG2937	Belongs to the GPAT DAPAT family
KAM497c_40750	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KAM497c_40760	COG3161	chorismate lyase activity
KAM497c_40770	COG1580	Controls the rotational direction of flagella during chemotaxis
KAM497c_40810	COG1609	Transcriptional regulator
KAM497c_40880	COG3307	-O-antigen
KAM497c_40900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KAM497c_40920	COG0156	8-amino-7-oxononanoate synthase activity
KAM497c_40930	COG1063	alcohol dehydrogenase
KAM497c_40970	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KAM497c_40980	COG2166	iron-sulfur cluster assembly
KAM497c_40990	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KAM497c_41010	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KAM497c_41020	COG0848	biopolymer transport protein
KAM497c_41030	COG0811	peptide transport
KAM497c_41040	COG0811	peptide transport
KAM497c_41060	COG2771	luxR family
KAM497c_41070	COG2176	DNA-directed DNA polymerase activity
KAM497c_41070	COG5002	protein histidine kinase activity
KAM497c_41080	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KAM497c_41090	COG1349	DNA-binding transcription factor activity
KAM497c_41100	COG0745	RESPONSE REGULATOR receiver
KAM497c_41110	COG2205	protein histidine kinase activity
KAM497c_41130	COG4452	Inner membrane protein CreD
KAM497c_41140	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KAM497c_41150	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KAM497c_41160	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KAM497c_41170	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KAM497c_41180	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KAM497c_41190	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KAM497c_41200	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KAM497c_41220	COG0356	it plays a direct role in the translocation of protons across the membrane
KAM497c_41240	COG1475	DNA binding
KAM497c_41250	COG1192	Involved in chromosome partitioning
KAM497c_41260	COG0357	Ribosomal RNA small subunit methyltransferase G
KAM497c_41270	COG0445	tRNA wobble uridine modification
KAM497c_41280	COG0716	FMN binding
KAM497c_41290	COG4774	siderophore transport
KAM497c_41300	COG4615	Cyclic peptide transporter
KAM497c_41310	COG1120	ATPase activity
KAM497c_41320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KAM497c_41350	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KAM497c_41360	COG0706	membrane insertase activity
KAM497c_41370	COG0594	ribonuclease P activity
KAM497c_41380	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KAM497c_41390	COG1126	abc transporter atp-binding protein
KAM497c_41420	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KAM497c_41530	COG3039	Transposase
KAM497c_41550	COG1484	DNA-dependent DNA replication
KAM497c_41560	COG4584	PFAM Integrase catalytic
KAM497c_41830	COG1484	DNA-dependent DNA replication
KAM497c_41840	COG4584	PFAM Integrase catalytic
KAM497c_41850	COG2974	May be involved in recombination
KAM497c_41860	COG3385	transposase activity
KAM497c_41990	COG1192	Involved in chromosome partitioning
KAM497c_42080	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KAM497c_42090	COG1061	Type III restriction enzyme res subunit
KAM497c_42100	COG1002	Type II restriction enzyme, methylase subunits
KAM497c_42130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KAM497c_42400	COG3385	transposase activity
KAM497c_42420	COG3385	transposase activity
KAM497c_42430	COG0653	protein targeting
KAM497c_42460	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KAM497c_42540	COG0714	Associated with various cellular activities
KAM497c_42670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KAM497c_42830	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM497c_42910	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM497c_42920	COG3041	Addiction module toxin RelE StbE family
KAM497c_42990	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM497c_43260	COG1396	sequence-specific DNA binding
KAM497c_43270	COG3550	peptidyl-serine autophosphorylation
KAM497c_43290	COG4584	PFAM Integrase catalytic
KAM497c_43300	COG1484	DNA-dependent DNA replication
KAM497c_43450	COG5433	transposase activity
KAM497c_43490	COG0789	Transcriptional regulator
KAM497c_43590	COG2176	DNA-directed DNA polymerase activity
KAM497c_43590	COG5002	protein histidine kinase activity
KAM497c_43720	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM497c_43830	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KAM497c_43860	COG1192	Involved in chromosome partitioning