locus-tag	class	description
NUITMVA2_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NUITMVA2_00020	COG0592	DNA-directed DNA polymerase activity
NUITMVA2_00040	COG0187	DNA topoisomerase II activity
NUITMVA2_00050	COG2207	Transcriptional regulator
NUITMVA2_00060	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NUITMVA2_00070	COG0071	Belongs to the small heat shock protein (HSP20) family
NUITMVA2_00080	COG0071	Belongs to the small heat shock protein (HSP20) family
NUITMVA2_00090	COG3977	Valine--pyruvate aminotransferase
NUITMVA2_00120	COG2814	Major facilitator Superfamily
NUITMVA2_00130	COG0745	RESPONSE REGULATOR receiver
NUITMVA2_00140	COG2205	protein histidine kinase activity
NUITMVA2_00210	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NUITMVA2_00220	COG4191	Histidine kinase
NUITMVA2_00220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NUITMVA2_00230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NUITMVA2_00240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUITMVA2_00250	COG1309	transcriptional regulator
NUITMVA2_00270	COG0561	phosphatase activity
NUITMVA2_00280	COG2267	carboxylic ester hydrolase activity
NUITMVA2_00290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NUITMVA2_00300	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NUITMVA2_00310	COG1758	RNA polymerase activity
NUITMVA2_00330	COG0859	PFAM glycosyl transferase family 9
NUITMVA2_00340	COG3642	lipopolysaccharide core region biosynthetic process
NUITMVA2_00420	COG0589	response to stress
NUITMVA2_00430	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NUITMVA2_00440	COG3706	GGDEF domain
NUITMVA2_00450	COG1528	Iron-storage protein
NUITMVA2_00460	COG2081	HI0933 family
NUITMVA2_00550	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NUITMVA2_00580	COG2223	nitrite transmembrane transporter activity
NUITMVA2_00590	COG4584	PFAM Integrase catalytic
NUITMVA2_00610	COG1484	DNA-dependent DNA replication
NUITMVA2_00620	COG2223	nitrite transmembrane transporter activity
NUITMVA2_00630	COG1280	lysine exporter protein (LysE YggA)
NUITMVA2_00660	COG3188	usher protein
NUITMVA2_00690	COG2197	response regulator
NUITMVA2_00700	COG2205	protein histidine kinase activity
NUITMVA2_00700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NUITMVA2_00720	COG3275	phosphorelay sensor kinase activity
NUITMVA2_00730	COG3279	Response regulator of the LytR AlgR family
NUITMVA2_00740	COG2223	nitrite transmembrane transporter activity
NUITMVA2_00750	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NUITMVA2_00810	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NUITMVA2_00820	COG2166	iron-sulfur cluster assembly
NUITMVA2_00830	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NUITMVA2_00870	COG1063	alcohol dehydrogenase
NUITMVA2_00880	COG0156	8-amino-7-oxononanoate synthase activity
NUITMVA2_00900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NUITMVA2_00990	COG1609	Transcriptional regulator
NUITMVA2_01030	COG1580	Controls the rotational direction of flagella during chemotaxis
NUITMVA2_01040	COG3161	chorismate lyase activity
NUITMVA2_01050	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NUITMVA2_01060	COG2937	Belongs to the GPAT DAPAT family
NUITMVA2_01070	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NUITMVA2_01100	COG0534	Mate efflux family protein
NUITMVA2_01110	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NUITMVA2_01120	COG2205	protein histidine kinase activity
NUITMVA2_01130	COG0745	RESPONSE REGULATOR receiver
NUITMVA2_01150	COG1045	serine acetyltransferase
NUITMVA2_01170	COG3074	FtsZ-dependent cytokinesis
NUITMVA2_01180	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
NUITMVA2_01190	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NUITMVA2_01190	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NUITMVA2_01200	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NUITMVA2_01210	COG1609	Transcriptional regulator
NUITMVA2_01220	COG3250	beta-galactosidase activity
NUITMVA2_01230	COG2731	YhcH YjgK YiaL family protein
NUITMVA2_01240	COG0531	amino acid
NUITMVA2_01250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NUITMVA2_01260	COG0531	amino acid
NUITMVA2_01270	COG0385	Bile acid
NUITMVA2_01280	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NUITMVA2_01330	COG0583	DNA-binding transcription factor activity
NUITMVA2_01340	COG1079	Belongs to the binding-protein-dependent transport system permease family
NUITMVA2_01350	COG4603	Belongs to the binding-protein-dependent transport system permease family
NUITMVA2_01360	COG3845	ABC transporter
NUITMVA2_01370	COG1744	ABC transporter substrate-binding protein PnrA-like
NUITMVA2_01380	COG0210	DNA helicase
NUITMVA2_01400	COG1943	Transposase
NUITMVA2_01410	COG0583	DNA-binding transcription factor activity
NUITMVA2_01480	COG0583	DNA-binding transcription factor activity
NUITMVA2_01510	COG1280	lysine exporter protein (LysE YggA)
NUITMVA2_01530	COG2962	Rard protein
NUITMVA2_01550	COG1012	belongs to the aldehyde dehydrogenase family
NUITMVA2_01560	COG1396	sequence-specific DNA binding
NUITMVA2_01570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NUITMVA2_01590	COG0519	Catalyzes the synthesis of GMP from XMP
NUITMVA2_01590	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NUITMVA2_01610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NUITMVA2_01650	COG1322	Protein conserved in bacteria
NUITMVA2_01660	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NUITMVA2_01670	COG0569	domain protein
NUITMVA2_01680	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NUITMVA2_01680	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NUITMVA2_01690	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NUITMVA2_01700	COG0242	peptide deformylase activity
NUITMVA2_01720	COG0758	DNA mediated transformation
NUITMVA2_01730	COG2922	Belongs to the Smg family
NUITMVA2_01740	COG0551	DNA topoisomerase type I activity
NUITMVA2_01750	COG0009	L-threonylcarbamoyladenylate synthase
NUITMVA2_01760	COG0408	coproporphyrinogen oxidase activity
NUITMVA2_01770	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NUITMVA2_01790	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NUITMVA2_01810	COG3078	GTPase activator activity
NUITMVA2_01830	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NUITMVA2_01840	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NUITMVA2_01860	COG3852	Histidine kinase
NUITMVA2_01880	COG0174	glutamine synthetase
NUITMVA2_01890	COG1217	gtp-binding protein TYPA
NUITMVA2_01900	COG1295	ribonuclease BN
NUITMVA2_01910	COG1490	D-aminoacyl-tRNA deacylase activity
NUITMVA2_01930	COG0456	acetyltransferase
NUITMVA2_01950	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NUITMVA2_01960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NUITMVA2_01970	COG2610	gluconate transmembrane transporter activity
NUITMVA2_01980	COG3265	gluconokinase activity
NUITMVA2_01990	COG0129	dihydroxy-acid dehydratase activity
NUITMVA2_02000	COG0800	Aldolase
NUITMVA2_02030	COG1609	Transcriptional regulator
NUITMVA2_02050	COG4942	peptidase
NUITMVA2_02060	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NUITMVA2_02070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NUITMVA2_02080	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
NUITMVA2_02090	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NUITMVA2_02100	COG0316	Belongs to the HesB IscA family
NUITMVA2_02100	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NUITMVA2_02110	COG1040	competence protein
NUITMVA2_02120	COG0596	Alpha beta hydrolase
NUITMVA2_02150	COG2183	response to ionizing radiation
NUITMVA2_02160	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NUITMVA2_02180	COG2205	protein histidine kinase activity
NUITMVA2_02200	COG0051	transcription antitermination factor activity, RNA binding
NUITMVA2_02210	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NUITMVA2_02220	COG0088	Forms part of the polypeptide exit tunnel
NUITMVA2_02230	COG0089	rRNA binding
NUITMVA2_02240	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NUITMVA2_02250	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NUITMVA2_02260	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NUITMVA2_02270	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NUITMVA2_02280	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NUITMVA2_02290	COG0255	Belongs to the universal ribosomal protein uL29 family
NUITMVA2_02300	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NUITMVA2_02310	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NUITMVA2_02320	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NUITMVA2_02330	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NUITMVA2_02340	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NUITMVA2_02350	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NUITMVA2_02360	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NUITMVA2_02370	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NUITMVA2_02380	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NUITMVA2_02390	COG1841	ribosomal large subunit assembly
NUITMVA2_02400	COG0200	Binds to the 23S rRNA
NUITMVA2_02410	COG0201	protein transport
NUITMVA2_02420	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NUITMVA2_02430	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NUITMVA2_02440	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NUITMVA2_02450	COG0202	RNA polymerase activity
NUITMVA2_02460	COG0203	ribosomal protein L17
NUITMVA2_02520	COG2249	NAD(P)H dehydrogenase (quinone) activity
NUITMVA2_02530	COG0583	DNA-binding transcription factor activity
NUITMVA2_02540	COG4221	oxidoreductase activity
NUITMVA2_02570	COG1770	oligopeptidase
NUITMVA2_02580	COG2358	TRAP transporter, solute receptor (TAXI family
NUITMVA2_02610	COG3714	YhhN family
NUITMVA2_02640	COG0583	DNA-binding transcription factor activity
NUITMVA2_02660	COG1301	dicarboxylic acid transport
NUITMVA2_02680	COG2095	MarC family integral membrane protein
NUITMVA2_02700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NUITMVA2_02720	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NUITMVA2_02740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NUITMVA2_02790	COG0742	ribosomal rna small subunit methyltransferase
NUITMVA2_02800	COG0552	protein localization to endoplasmic reticulum
NUITMVA2_02810	COG2884	Cell division ATP-binding protein ftsE
NUITMVA2_02820	COG2177	Part of the ABC transporter FtsEX involved in
NUITMVA2_02840	COG0288	reversible hydration of carbon dioxide
NUITMVA2_02850	COG2188	Transcriptional regulator
NUITMVA2_02860	COG1228	amidohydrolase
NUITMVA2_02870	COG0010	Belongs to the arginase family
NUITMVA2_02880	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NUITMVA2_02890	COG2986	histidine ammonia-lyase
NUITMVA2_02900	COG0387	Pfam Sodium calcium exchanger
NUITMVA2_02910	COG2200	EAL domain
NUITMVA2_03010	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NUITMVA2_03020	COG1459	type II secretion system
NUITMVA2_03110	COG1077	Cell shape determining protein MreB Mrl
NUITMVA2_03120	COG1792	Involved in formation and maintenance of cell shape
NUITMVA2_03130	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NUITMVA2_03140	COG0424	maF-like protein
NUITMVA2_03150	COG1530	ribonuclease E activity
NUITMVA2_03160	COG3164	Protein of unknown function
NUITMVA2_03170	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NUITMVA2_03180	COG0312	modulator of DNA gyrase
NUITMVA2_03210	COG0477	Major facilitator Superfamily
NUITMVA2_03230	COG2321	neutral zinc metallopeptidase
NUITMVA2_03300	COG0189	ligase activity
NUITMVA2_03310	COG0642	Histidine kinase
NUITMVA2_03320	COG0745	RESPONSE REGULATOR receiver
NUITMVA2_03350	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NUITMVA2_03360	COG0352	thiamine-phosphate diphosphorylase activity
NUITMVA2_03370	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NUITMVA2_03390	COG2022	thiamine diphosphate biosynthetic process
NUITMVA2_03400	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NUITMVA2_03440	COG0110	maltose O-acetyltransferase activity
NUITMVA2_03470	COG3932	Exopolysaccharide synthesis, ExoD
NUITMVA2_03500	COG1733	regulation of RNA biosynthetic process
NUITMVA2_03560	COG2226	methyltransferase
NUITMVA2_03580	COG1494	fructose-1,6-bisphosphatase
NUITMVA2_03600	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NUITMVA2_03610	COG5007	Belongs to the BolA IbaG family
NUITMVA2_03630	COG2854	intermembrane phospholipid transfer
NUITMVA2_03640	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NUITMVA2_03650	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NUITMVA2_03660	COG1127	ABC transporter
NUITMVA2_03670	COG0517	IMP dehydrogenase activity
NUITMVA2_03670	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NUITMVA2_03680	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NUITMVA2_03700	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NUITMVA2_03710	COG1137	ATPase activity
NUITMVA2_03720	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NUITMVA2_03740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NUITMVA2_03750	COG1660	Displays ATPase and GTPase activities
NUITMVA2_03760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NUITMVA2_03800	COG3964	amidohydrolase
NUITMVA2_03860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NUITMVA2_03870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NUITMVA2_03890	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NUITMVA2_03900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NUITMVA2_03910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NUITMVA2_03920	COG0723	plastoquinol--plastocyanin reductase activity
NUITMVA2_03930	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NUITMVA2_03940	COG2857	Cytochrome c1
NUITMVA2_03950	COG0625	glutathione transferase activity
NUITMVA2_03960	COG2969	positive regulation of protein catabolic process
NUITMVA2_03970	COG2823	Periplasmic or secreted lipoprotein
NUITMVA2_03980	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NUITMVA2_03990	COG0792	nuclease activity
NUITMVA2_04000	COG3107	peptidoglycan biosynthetic process
NUITMVA2_04010	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NUITMVA2_04020	COG2001	Belongs to the MraZ family
NUITMVA2_04030	COG0275	rRNA processing
NUITMVA2_04040	COG3116	cell division
NUITMVA2_04050	COG0768	penicillin binding
NUITMVA2_04060	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NUITMVA2_04070	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NUITMVA2_04080	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NUITMVA2_04090	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NUITMVA2_04100	COG0772	Belongs to the SEDS family
NUITMVA2_04110	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NUITMVA2_04120	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NUITMVA2_04130	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NUITMVA2_04140	COG0849	cell division
NUITMVA2_04150	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NUITMVA2_04160	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NUITMVA2_04180	COG0653	protein targeting
NUITMVA2_04200	COG0494	nUDIX hydrolase
NUITMVA2_04210	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
NUITMVA2_04220	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
NUITMVA2_04250	COG1459	type II secretion system
NUITMVA2_04260	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NUITMVA2_04310	COG2186	Transcriptional regulator
NUITMVA2_04320	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NUITMVA2_04330	COG0508	dehydrogenase complex catalyzes the overall conversion of
NUITMVA2_04340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NUITMVA2_04360	COG0840	transmembrane signaling receptor activity
NUITMVA2_04370	COG0840	transmembrane signaling receptor activity
NUITMVA2_04380	COG1752	Esterase of the alpha-beta hydrolase superfamily
NUITMVA2_04390	COG1049	propionate catabolic process, 2-methylcitrate cycle
NUITMVA2_04400	COG2200	EAL domain
NUITMVA2_04410	COG2200	EAL domain
NUITMVA2_04410	COG2771	luxR family
NUITMVA2_04430	COG1280	lysine exporter protein (LysE YggA)
NUITMVA2_04450	COG0523	cobalamin synthesis protein
NUITMVA2_04460	COG0477	Major facilitator Superfamily
NUITMVA2_04490	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NUITMVA2_04500	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NUITMVA2_04550	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NUITMVA2_04580	COG2801	Transposase and inactivated derivatives
NUITMVA2_04600	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NUITMVA2_04610	COG0732	type I restriction modification DNA specificity domain
NUITMVA2_04620	COG1401	restriction endodeoxyribonuclease activity
NUITMVA2_04620	COG1401	restriction endodeoxyribonuclease activity
NUITMVA2_04640	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NUITMVA2_04710	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NUITMVA2_04740	COG1546	Belongs to the CinA family
NUITMVA2_04750	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NUITMVA2_04760	COG2137	regulation of response to DNA damage stimulus
NUITMVA2_04770	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NUITMVA2_04780	COG0527	aspartate kinase activity
NUITMVA2_04790	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NUITMVA2_04800	COG1686	Belongs to the peptidase S11 family
NUITMVA2_04810	COG0586	Pfam SNARE associated Golgi protein
NUITMVA2_04820	COG1253	flavin adenine dinucleotide binding
NUITMVA2_04830	COG0525	valine-tRNA ligase activity
NUITMVA2_04840	COG2927	DNA polymerase III (CHI subunit)
NUITMVA2_04850	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NUITMVA2_04860	COG0795	lipopolysaccharide-transporting ATPase activity
NUITMVA2_04870	COG0795	lipopolysaccharide-transporting ATPase activity
NUITMVA2_04900	COG0004	ammonium transporteR
NUITMVA2_04910	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NUITMVA2_04940	COG2165	general secretion pathway protein
NUITMVA2_04950	COG0084	hydrolase, TatD family'
NUITMVA2_04960	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NUITMVA2_04980	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NUITMVA2_04990	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NUITMVA2_05000	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NUITMVA2_05010	COG0813	purine-nucleoside phosphorylase activity
NUITMVA2_05020	COG5002	protein histidine kinase activity
NUITMVA2_05020	COG5001	Diguanylate cyclase
NUITMVA2_05020	COG3447	MASE1 domain protein
NUITMVA2_05040	COG0560	Phosphoserine phosphatase
NUITMVA2_05070	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NUITMVA2_05090	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
NUITMVA2_05100	COG0776	regulation of translation
NUITMVA2_05130	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NUITMVA2_05140	COG0735	belongs to the Fur family
NUITMVA2_05180	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NUITMVA2_05190	COG0513	Belongs to the DEAD box helicase family
NUITMVA2_05200	COG3022	response to hydroperoxide
NUITMVA2_05230	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NUITMVA2_05240	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NUITMVA2_05250	COG0762	integral membrane protein
NUITMVA2_05260	COG1872	DUF167
NUITMVA2_05300	COG3112	Uncharacterised protein family (UPF0231)
NUITMVA2_05310	COG3835	regulator
NUITMVA2_05320	COG2610	gluconate transmembrane transporter activity
NUITMVA2_05330	COG1929	Belongs to the glycerate kinase type-1 family
NUITMVA2_05360	COG0583	DNA-binding transcription factor activity
NUITMVA2_05370	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NUITMVA2_05400	COG0347	Belongs to the P(II) protein family
NUITMVA2_05410	COG1840	ABC-type Fe3 transport system, periplasmic component
NUITMVA2_05430	COG3842	ATPase activity
NUITMVA2_05440	COG2837	iron assimilation
NUITMVA2_05450	COG1438	arginine binding
NUITMVA2_05460	COG1126	abc transporter atp-binding protein
NUITMVA2_05470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NUITMVA2_05480	COG4215	(ABC) transporter
NUITMVA2_05490	COG4160	amino acid transport
NUITMVA2_05500	COG0039	L-malate dehydrogenase activity
NUITMVA2_05520	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
NUITMVA2_05530	COG1017	nitric oxide dioxygenase activity
NUITMVA2_05530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NUITMVA2_05550	COG4536	flavin adenine dinucleotide binding
NUITMVA2_05560	COG4137	Cytochrome C assembly protein
NUITMVA2_05570	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NUITMVA2_05580	COG0228	four-way junction DNA binding
NUITMVA2_05590	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NUITMVA2_05600	COG0336	Belongs to the RNA methyltransferase TrmD family
NUITMVA2_05610	COG0335	large ribosomal subunit rRNA binding
NUITMVA2_05640	COG1051	belongs to the nudix hydrolase family
NUITMVA2_05660	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NUITMVA2_05670	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NUITMVA2_05680	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NUITMVA2_05780	COG5301	cellulose 1,4-beta-cellobiosidase activity
NUITMVA2_05970	COG4695	Portal protein
NUITMVA2_06210	COG4974	Belongs to the 'phage' integrase family
NUITMVA2_06220	COG0583	DNA-binding transcription factor activity
NUITMVA2_06230	COG0640	Transcriptional regulator
NUITMVA2_06240	COG0268	Binds directly to 16S ribosomal RNA
NUITMVA2_06250	COG0728	peptidoglycan biosynthetic process
NUITMVA2_06260	COG0196	riboflavin kinase activity
NUITMVA2_06270	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NUITMVA2_06280	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NUITMVA2_06290	COG1047	Peptidyl-prolyl cis-trans
NUITMVA2_06300	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NUITMVA2_06380	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NUITMVA2_06380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NUITMVA2_06410	COG1854	S-ribosylhomocysteine lyase activity
NUITMVA2_06420	COG3706	GGDEF domain
NUITMVA2_06430	COG0557	exoribonuclease II activity
NUITMVA2_06440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NUITMVA2_06460	COG2153	protein acetylation
NUITMVA2_06480	COG1914	H( )-stimulated, divalent metal cation uptake system
NUITMVA2_06490	COG0360	Binds together with S18 to 16S ribosomal RNA
NUITMVA2_06500	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NUITMVA2_06510	COG0359	binds to the 23S rRNA
NUITMVA2_06590	COG1238	metal cluster binding
NUITMVA2_06600	COG0612	Peptidase, M16
NUITMVA2_06610	COG2918	glutathione biosynthetic process
NUITMVA2_06620	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NUITMVA2_06630	COG1027	Aspartate ammonia-lyase
NUITMVA2_06640	COG3030	protein affecting phage T7 exclusion by the F plasmid
NUITMVA2_06650	COG0534	Mate efflux family protein
NUITMVA2_06660	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NUITMVA2_06670	COG0459	protein refolding
NUITMVA2_06710	COG0564	pseudouridine synthase activity
NUITMVA2_06720	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NUITMVA2_06730	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NUITMVA2_06750	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NUITMVA2_06760	COG4208	sulfate ABC transporter
NUITMVA2_06770	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NUITMVA2_06780	COG0583	DNA-binding transcription factor activity
NUITMVA2_06790	COG3397	chitin binding
NUITMVA2_06800	COG0840	transmembrane signaling receptor activity
NUITMVA2_06850	COG1328	CTP reductase activity
NUITMVA2_06860	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NUITMVA2_06890	COG1448	Aminotransferase
NUITMVA2_06900	COG2194	sulfuric ester hydrolase activity
NUITMVA2_06950	COG1215	transferase activity, transferring glycosyl groups
NUITMVA2_06960	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NUITMVA2_06970	COG0457	Tetratricopeptide repeat
NUITMVA2_06970	COG3118	belongs to the thioredoxin family
NUITMVA2_06980	COG0457	Tetratricopeptide repeat
NUITMVA2_06980	COG3118	belongs to the thioredoxin family
NUITMVA2_07060	COG2015	COG2015, Alkyl sulfatase and related hydrolases
NUITMVA2_07070	COG0513	Belongs to the DEAD box helicase family
NUITMVA2_07080	COG0840	transmembrane signaling receptor activity
NUITMVA2_07100	COG4166	transmembrane transport
NUITMVA2_07130	COG1024	Enoyl-CoA hydratase
NUITMVA2_07160	COG4221	oxidoreductase activity
NUITMVA2_07170	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NUITMVA2_07180	COG0442	prolyl-tRNA aminoacylation
NUITMVA2_07190	COG0840	transmembrane signaling receptor activity
NUITMVA2_07200	COG0632	four-way junction helicase activity
NUITMVA2_07210	COG2255	four-way junction helicase activity
NUITMVA2_07220	COG1271	oxidase subunit
NUITMVA2_07230	COG1294	oxidase, subunit
NUITMVA2_07240	COG3790	cyd operon protein YbgE
NUITMVA2_07250	COG0824	Thioesterase
NUITMVA2_07260	COG0811	peptide transport
NUITMVA2_07290	COG0823	Involved in the tonB-independent uptake of proteins
NUITMVA2_07300	COG2885	chlorophyll binding
NUITMVA2_07310	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
NUITMVA2_07320	COG0840	transmembrane signaling receptor activity
NUITMVA2_07330	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NUITMVA2_07350	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NUITMVA2_07360	COG1640	4-alpha-glucanotransferase
NUITMVA2_07370	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NUITMVA2_07430	COG2130	NADP-dependent
NUITMVA2_07440	COG1846	Transcriptional regulator
NUITMVA2_07500	COG0561	phosphatase activity
NUITMVA2_07530	COG0733	neurotransmitter:sodium symporter activity
NUITMVA2_07540	COG0733	neurotransmitter:sodium symporter activity
NUITMVA2_07570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NUITMVA2_07600	COG1794	racemase activity, acting on amino acids and derivatives
NUITMVA2_07620	COG1022	Amp-dependent synthetase and ligase
NUITMVA2_07640	COG0456	acetyltransferase
NUITMVA2_07670	COG2425	protein containing a von Willebrand factor type A (vWA) domain
NUITMVA2_07680	COG5001	Diguanylate cyclase
NUITMVA2_07680	COG5002	protein histidine kinase activity
NUITMVA2_07740	COG0456	acetyltransferase
NUITMVA2_07750	COG1902	pentaerythritol trinitrate reductase activity
NUITMVA2_07780	COG2957	Belongs to the agmatine deiminase family
NUITMVA2_07790	COG0154	amidase activity
NUITMVA2_07810	COG2801	Transposase and inactivated derivatives
NUITMVA2_07870	COG1917	Cupin 2, conserved barrel domain protein
NUITMVA2_07870	COG2207	Transcriptional regulator
NUITMVA2_07890	COG0513	Belongs to the DEAD box helicase family
NUITMVA2_07900	COG2199	diguanylate cyclase activity
NUITMVA2_07900	COG2203	Gaf domain
NUITMVA2_07970	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
NUITMVA2_07990	COG0577	efflux transmembrane transporter activity
NUITMVA2_07990	COG1136	(ABC) transporter
NUITMVA2_08000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUITMVA2_08010	COG0745	RESPONSE REGULATOR receiver
NUITMVA2_08020	COG2205	protein histidine kinase activity
NUITMVA2_08090	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NUITMVA2_08110	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NUITMVA2_08120	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
NUITMVA2_08130	COG1178	ABC-type Fe3 transport system permease component
NUITMVA2_08140	COG4143	(ABC) transporter
NUITMVA2_08170	COG0066	3-isopropylmalate dehydratase activity
NUITMVA2_08180	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NUITMVA2_08190	COG0473	3-isopropylmalate dehydrogenase activity
NUITMVA2_08200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NUITMVA2_08220	COG0671	phosphoesterase, PA-phosphatase related
NUITMVA2_08250	COG0028	Belongs to the TPP enzyme family
NUITMVA2_08260	COG0440	acetolactate synthase activity
NUITMVA2_08270	COG0857	belongs to the CobB CobQ family
NUITMVA2_08270	COG0280	phosphate acetyltransferase
NUITMVA2_08280	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NUITMVA2_08290	COG3092	negative regulation of chromosome organization
NUITMVA2_08300	COG3013	Belongs to the UPF0304 family
NUITMVA2_08310	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NUITMVA2_08320	COG2716	regulation of RNA biosynthetic process
NUITMVA2_08330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NUITMVA2_08340	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
NUITMVA2_08350	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NUITMVA2_08380	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
NUITMVA2_08420	COG0784	Response regulator, receiver
NUITMVA2_08420	COG2198	Histidine kinase
NUITMVA2_08420	COG5002	protein histidine kinase activity
NUITMVA2_08430	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NUITMVA2_08460	COG0784	Response regulator, receiver
NUITMVA2_08460	COG2205	protein histidine kinase activity
NUITMVA2_08500	COG1464	Belongs to the NlpA lipoprotein family
NUITMVA2_08510	COG2011	ABC-type metal ion transport system permease component
NUITMVA2_08520	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NUITMVA2_08560	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NUITMVA2_08560	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NUITMVA2_08570	COG0802	atpase or kinase
NUITMVA2_08590	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NUITMVA2_08600	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NUITMVA2_08610	COG1923	regulation of RNA biosynthetic process
NUITMVA2_08620	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NUITMVA2_08630	COG0330	HflC and HflK could
NUITMVA2_08640	COG0330	HflC and HflK could
NUITMVA2_08650	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
NUITMVA2_08660	COG0142	geranyltranstransferase activity
NUITMVA2_08670	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NUITMVA2_08680	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NUITMVA2_08690	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NUITMVA2_08700	COG3314	Sporulation integral membrane protein YlbJ
NUITMVA2_08710	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NUITMVA2_08720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NUITMVA2_08740	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NUITMVA2_08750	COG2967	ApaG domain
NUITMVA2_08760	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NUITMVA2_08770	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NUITMVA2_08790	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
NUITMVA2_08800	COG3178	'Phosphotransferase
NUITMVA2_08810	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NUITMVA2_08820	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NUITMVA2_08830	COG2252	PERMEase
NUITMVA2_08850	COG0488	(ABC) transporter
NUITMVA2_08860	COG0582	viral genome integration into host DNA
NUITMVA2_09030	COG1846	Transcriptional regulator
NUITMVA2_09060	COG3646	Phage regulatory protein
NUITMVA2_09160	COG1802	Transcriptional regulator
NUITMVA2_09160	COG4626	Terminase
NUITMVA2_09370	COG0741	lytic transglycosylase activity
NUITMVA2_09380	COG0463	Glycosyl transferase, family 2
NUITMVA2_09400	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NUITMVA2_09460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NUITMVA2_09480	COG3721	Heme iron utilization protein
NUITMVA2_09490	COG0748	coenzyme F420 binding
NUITMVA2_09540	COG2814	Major facilitator Superfamily
NUITMVA2_09550	COG2202	Pas domain
NUITMVA2_09550	COG2205	protein histidine kinase activity
NUITMVA2_09570	COG2226	methyltransferase
NUITMVA2_09590	COG1765	OsmC-like protein
NUITMVA2_09620	COG3954	Phosphoribulokinase
NUITMVA2_09630	COG3089	Belongs to the UPF0270 family
NUITMVA2_09640	COG2203	Gaf domain
NUITMVA2_09640	COG3706	GGDEF domain
NUITMVA2_09640	COG4251	negative regulation of phosphorylation
NUITMVA2_09640	COG5001	Diguanylate cyclase
NUITMVA2_09650	COG0429	hydrolase of the alpha beta-hydrolase fold
NUITMVA2_09660	COG0784	Response regulator, receiver
NUITMVA2_09660	COG0835	chemotaxis
NUITMVA2_09680	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
NUITMVA2_09690	COG1047	Peptidyl-prolyl cis-trans
NUITMVA2_09700	COG2900	Belongs to the SlyX family
NUITMVA2_09720	COG0545	Peptidyl-prolyl cis-trans isomerase
NUITMVA2_09730	COG2204	response regulator
NUITMVA2_09770	COG0737	Belongs to the 5'-nucleotidase family
NUITMVA2_09800	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NUITMVA2_09810	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NUITMVA2_09810	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NUITMVA2_09810	COG0506	proline dehydrogenase activity
NUITMVA2_09830	COG0114	fumarate hydratase activity
NUITMVA2_09850	COG1566	PFAM secretion protein HlyD family protein
NUITMVA2_09960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NUITMVA2_09980	COG1280	lysine exporter protein (LysE YggA)
NUITMVA2_09990	COG0826	peptidase U32
NUITMVA2_10000	COG0826	peptidase U32
NUITMVA2_10060	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NUITMVA2_10110	COG0300	oxidoreductase activity
NUITMVA2_10150	COG2610	gluconate transmembrane transporter activity
NUITMVA2_10160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NUITMVA2_10170	COG3622	Belongs to the hyi family
NUITMVA2_10180	COG0235	Class ii aldolase
NUITMVA2_10200	COG2084	Dehydrogenase
NUITMVA2_10210	COG1349	DNA-binding transcription factor activity
NUITMVA2_10230	COG2133	pyrroloquinoline quinone binding
NUITMVA2_10240	COG2326	polyphosphate kinase activity
NUITMVA2_10300	COG2801	Transposase and inactivated derivatives
NUITMVA2_10330	COG4397	Mu-like prophage major head subunit gpT
NUITMVA2_10390	COG2020	methyltransferase activity
NUITMVA2_10410	COG2916	Histone family protein nucleoid-structuring protein H-NS
NUITMVA2_10490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NUITMVA2_10500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUITMVA2_10590	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NUITMVA2_10600	COG4584	PFAM Integrase catalytic
NUITMVA2_10610	COG1484	DNA-dependent DNA replication
NUITMVA2_10630	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NUITMVA2_10710	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NUITMVA2_10760	COG0210	DNA helicase
NUITMVA2_10790	COG2801	Transposase and inactivated derivatives
NUITMVA2_10860	COG0077	Prephenate dehydratase
NUITMVA2_10860	COG1605	Chorismate mutase
NUITMVA2_10910	COG3272	Protein of unknown function (DUF1722)
NUITMVA2_10920	COG0789	Transcriptional regulator
NUITMVA2_10930	COG0415	Belongs to the DNA photolyase family
NUITMVA2_10950	COG4221	oxidoreductase activity
NUITMVA2_10980	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NUITMVA2_11030	COG0783	Belongs to the Dps family
NUITMVA2_11040	COG1151	hydroxylamine reductase activity
NUITMVA2_11050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NUITMVA2_11060	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NUITMVA2_11080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NUITMVA2_11090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUITMVA2_11110	COG5002	protein histidine kinase activity
NUITMVA2_11110	COG5000	phosphorelay sensor kinase activity
NUITMVA2_11130	COG0659	secondary active sulfate transmembrane transporter activity
NUITMVA2_11150	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NUITMVA2_11160	COG1666	GTP binding
NUITMVA2_11180	COG2211	Major facilitator Superfamily
NUITMVA2_11200	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NUITMVA2_11220	COG2813	Specifically methylates the guanine in position
NUITMVA2_11230	COG0271	Belongs to the BolA IbaG family
NUITMVA2_11240	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NUITMVA2_11250	COG1805	sodium ion transport
NUITMVA2_11260	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NUITMVA2_11270	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NUITMVA2_11280	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NUITMVA2_11290	COG2871	sodium ion transport
NUITMVA2_11300	COG1477	protein flavinylation
NUITMVA2_11330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NUITMVA2_11340	COG0840	transmembrane signaling receptor activity
NUITMVA2_11350	COG0583	DNA-binding transcription factor activity
NUITMVA2_11380	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
NUITMVA2_11400	COG0473	3-isopropylmalate dehydrogenase activity
NUITMVA2_11410	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NUITMVA2_11420	COG1611	Belongs to the LOG family
NUITMVA2_11450	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NUITMVA2_11450	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NUITMVA2_11470	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
NUITMVA2_11520	COG3098	single-species biofilm formation
NUITMVA2_11530	COG0564	pseudouridine synthase activity
NUITMVA2_11550	COG4580	involved in the transport of maltose and maltodextrins
NUITMVA2_11570	COG1263	PTS System
NUITMVA2_11570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NUITMVA2_11590	COG2171	N-acyltransferase activity
NUITMVA2_11600	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NUITMVA2_11610	COG0024	Methionine aminopeptidase
NUITMVA2_11620	COG0052	Belongs to the universal ribosomal protein uS2 family
NUITMVA2_11630	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NUITMVA2_11640	COG0528	UMP kinase activity
NUITMVA2_11650	COG0233	cytoplasmic translational termination
NUITMVA2_11660	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NUITMVA2_11670	COG0575	Belongs to the CDS family
NUITMVA2_11680	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NUITMVA2_11690	COG0750	zinc metalloprotease
NUITMVA2_11720	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NUITMVA2_11730	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NUITMVA2_11740	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NUITMVA2_11750	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NUITMVA2_11760	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NUITMVA2_11770	COG0587	DNA-directed DNA polymerase activity
NUITMVA2_11780	COG0825	malonyl-CoA metabolic process
NUITMVA2_11810	COG0814	amino acid
NUITMVA2_11830	COG0531	amino acid
NUITMVA2_11850	COG0488	(ABC) transporter
NUITMVA2_11880	COG0037	tRNA processing
NUITMVA2_11890	COG3706	GGDEF domain
NUITMVA2_11970	COG0366	Alpha amylase catalytic
NUITMVA2_12000	COG0463	Glycosyl transferase, family 2
NUITMVA2_12030	COG2989	Protein conserved in bacteria
NUITMVA2_12040	COG3108	Peptidase M15
NUITMVA2_12060	COG2860	membrane
NUITMVA2_12080	COG1196	nuclear chromosome segregation
NUITMVA2_12090	COG3115	cell septum assembly
NUITMVA2_12100	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NUITMVA2_12120	COG1328	CTP reductase activity
NUITMVA2_12130	COG0602	queuosine metabolic process
NUITMVA2_12180	COG1566	PFAM secretion protein HlyD family protein
NUITMVA2_12200	COG3290	protein histidine kinase activity
NUITMVA2_12230	COG0667	Aldo Keto reductase
NUITMVA2_12250	COG0697	spore germination
NUITMVA2_12280	COG3284	Transcriptional regulator
NUITMVA2_12290	COG3706	GGDEF domain
NUITMVA2_12300	COG0346	lactoylglutathione lyase activity
NUITMVA2_12310	COG0745	RESPONSE REGULATOR receiver
NUITMVA2_12320	COG5002	protein histidine kinase activity
NUITMVA2_12340	COG4783	chaperone-mediated protein folding
NUITMVA2_12380	COG0545	Peptidyl-prolyl cis-trans isomerase
NUITMVA2_12390	COG1131	(ABC) transporter
NUITMVA2_12400	COG0815	Transfers the fatty acyl group on membrane lipoproteins
NUITMVA2_12420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NUITMVA2_12430	COG4597	amino acid ABC transporter
NUITMVA2_12440	COG0765	amino acid transport
NUITMVA2_12450	COG1126	abc transporter atp-binding protein
NUITMVA2_12470	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
NUITMVA2_12480	COG0678	peroxiredoxin activity
NUITMVA2_12500	COG0019	diaminopimelate decarboxylase activity
NUITMVA2_12510	COG1115	amino acid carrier protein
NUITMVA2_12520	COG0095	Lipoate-protein ligase
NUITMVA2_12530	COG2233	PERMEase
NUITMVA2_12580	COG2207	Transcriptional regulator
NUITMVA2_12590	COG0281	malic enzyme
NUITMVA2_12650	COG0733	neurotransmitter:sodium symporter activity
NUITMVA2_12660	COG1752	Esterase of the alpha-beta hydrolase superfamily
NUITMVA2_12670	COG3706	GGDEF domain
NUITMVA2_12690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NUITMVA2_12700	COG1032	radical SAM domain protein
NUITMVA2_12710	COG2319	Wd-40 repeat
NUITMVA2_12710	COG3903	Transcriptional regulator
NUITMVA2_12750	COG0673	inositol 2-dehydrogenase activity
NUITMVA2_12760	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NUITMVA2_12770	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NUITMVA2_12780	COG0739	heme binding
NUITMVA2_12780	COG0741	lytic transglycosylase activity
NUITMVA2_12780	COG1196	nuclear chromosome segregation
NUITMVA2_12830	COG0788	formyltetrahydrofolate deformylase activity
NUITMVA2_12840	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NUITMVA2_12860	COG3118	belongs to the thioredoxin family
NUITMVA2_12880	COG0791	NLP P60 protein
NUITMVA2_12890	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
NUITMVA2_12930	COG3318	Belongs to the UPF0149 family
NUITMVA2_12930	COG3012	SEC-C Motif Domain Protein
NUITMVA2_12970	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NUITMVA2_13060	COG2003	Belongs to the UPF0758 family
NUITMVA2_13150	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NUITMVA2_13190	COG3311	Transcriptional regulator
NUITMVA2_13210	COG0582	viral genome integration into host DNA
NUITMVA2_13220	COG0784	Response regulator, receiver
NUITMVA2_13220	COG2205	protein histidine kinase activity
NUITMVA2_13250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NUITMVA2_13250	COG2205	protein histidine kinase activity
NUITMVA2_13260	COG3384	dioxygenase
NUITMVA2_13280	COG1283	sodium-dependent phosphate transmembrane transporter activity
NUITMVA2_13300	COG0531	amino acid
NUITMVA2_13310	COG0531	amino acid
NUITMVA2_13340	COG1012	belongs to the aldehyde dehydrogenase family
NUITMVA2_13350	COG1396	sequence-specific DNA binding
NUITMVA2_13350	COG1917	Cupin 2, conserved barrel domain protein
NUITMVA2_13360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NUITMVA2_13430	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NUITMVA2_13430	COG4651	solute:proton antiporter activity
NUITMVA2_13460	COG2974	May be involved in recombination
NUITMVA2_13470	COG1247	-acetyltransferase
NUITMVA2_13490	COG0420	3'-5' exonuclease activity
NUITMVA2_13510	COG3038	cytochrome b561
NUITMVA2_13520	COG2190	(PTS) system
NUITMVA2_13540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NUITMVA2_13550	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NUITMVA2_13560	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NUITMVA2_13590	COG1720	tRNA m6t6A37 methyltransferase activity
NUITMVA2_13630	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NUITMVA2_13640	COG4988	ABC transporter
NUITMVA2_13650	COG0745	RESPONSE REGULATOR receiver
NUITMVA2_13670	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NUITMVA2_13700	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
NUITMVA2_13710	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
NUITMVA2_13730	COG0083	homoserine kinase activity
NUITMVA2_13740	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NUITMVA2_13800	COG1943	Transposase
NUITMVA2_13820	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NUITMVA2_13840	COG3220	belongs to the UPF0276 family
NUITMVA2_13900	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NUITMVA2_13910	COG1289	transmembrane transporter activity
NUITMVA2_13920	COG1763	Mo-molybdopterin cofactor biosynthetic process
NUITMVA2_13930	COG0746	molybdenum cofactor guanylyltransferase activity
NUITMVA2_13940	COG0281	malic enzyme
NUITMVA2_14010	COG1196	nuclear chromosome segregation
NUITMVA2_14010	COG3264	Mechanosensitive ion channel
NUITMVA2_14040	COG2850	peptidyl-arginine hydroxylation
NUITMVA2_14050	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NUITMVA2_14060	COG2915	High frequency lysogenization protein hflD homolog
NUITMVA2_14070	COG0482	sulfurtransferase activity
NUITMVA2_14090	COG1187	pseudouridine synthase activity
NUITMVA2_14100	COG0456	acetyltransferase
NUITMVA2_14190	COG0538	isocitrate dehydrogenase activity
NUITMVA2_14210	COG3048	D-serine ammonia-lyase activity
NUITMVA2_14220	COG0583	DNA-binding transcription factor activity
NUITMVA2_14230	COG2916	Histone family protein nucleoid-structuring protein H-NS
NUITMVA2_14240	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NUITMVA2_14250	COG2375	cellular response to nickel ion
NUITMVA2_14260	COG1538	Outer membrane efflux protein
NUITMVA2_14270	COG0577	efflux transmembrane transporter activity
NUITMVA2_14270	COG1136	(ABC) transporter
NUITMVA2_14280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUITMVA2_14300	COG0497	DNA recombination
NUITMVA2_14310	COG3706	GGDEF domain
NUITMVA2_14320	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NUITMVA2_14340	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NUITMVA2_14350	COG0443	Heat shock 70 kDa protein
NUITMVA2_14360	COG0484	heat shock protein binding
NUITMVA2_14420	COG1285	pathogenesis
NUITMVA2_14440	COG0446	pyridine nucleotide-disulphide oxidoreductase
NUITMVA2_14460	COG0640	Transcriptional regulator
NUITMVA2_14530	COG0095	Lipoate-protein ligase
NUITMVA2_14560	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NUITMVA2_14570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUITMVA2_14590	COG0708	Exodeoxyribonuclease III
NUITMVA2_14610	COG0745	RESPONSE REGULATOR receiver
NUITMVA2_14640	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
NUITMVA2_14670	COG1846	Transcriptional regulator
NUITMVA2_14710	COG0583	DNA-binding transcription factor activity
NUITMVA2_14720	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NUITMVA2_14730	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NUITMVA2_14740	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NUITMVA2_14750	COG1845	cytochrome c oxidase, subunit III
NUITMVA2_14760	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NUITMVA2_14770	COG0109	protoheme IX farnesyltransferase activity
NUITMVA2_14780	COG2814	Major facilitator Superfamily
NUITMVA2_14790	COG5507	3-demethylubiquinone-9 3-methyltransferase
NUITMVA2_14870	COG2801	Transposase and inactivated derivatives
NUITMVA2_14880	COG0159	tryptophan synthase activity
NUITMVA2_14890	COG0133	tryptophan synthase activity
NUITMVA2_14900	COG0135	phosphoribosylanthranilate isomerase activity
NUITMVA2_14900	COG0134	indole-3-glycerol-phosphate synthase activity
NUITMVA2_14910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NUITMVA2_14920	COG0512	Glutamine amidotransferase of anthranilate synthase
NUITMVA2_14920	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NUITMVA2_14930	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NUITMVA2_14940	COG0613	PHP domain protein
NUITMVA2_14950	COG0009	L-threonylcarbamoyladenylate synthase
NUITMVA2_14970	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NUITMVA2_14990	COG1946	Acyl-CoA thioesterase
NUITMVA2_15020	COG1309	transcriptional regulator
NUITMVA2_15030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUITMVA2_15040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NUITMVA2_15150	COG2003	Belongs to the UPF0758 family
NUITMVA2_15180	COG4584	PFAM Integrase catalytic
NUITMVA2_15190	COG1484	DNA-dependent DNA replication
NUITMVA2_15200	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NUITMVA2_15250	COG0583	DNA-binding transcription factor activity
NUITMVA2_15290	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NUITMVA2_15310	COG1960	acyl-CoA dehydrogenase activity
NUITMVA2_15320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NUITMVA2_15340	COG0469	pyruvate kinase activity
NUITMVA2_15350	COG1737	Transcriptional regulator
NUITMVA2_15390	COG0675	Transposase, IS605 OrfB family
NUITMVA2_15410	COG1088	dTDP-glucose 4,6-dehydratase activity
NUITMVA2_15430	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NUITMVA2_15440	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NUITMVA2_15450	COG2089	acid synthase
NUITMVA2_15530	COG1215	transferase activity, transferring glycosyl groups
NUITMVA2_15540	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NUITMVA2_15580	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
NUITMVA2_15590	COG3039	Transposase
NUITMVA2_15610	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NUITMVA2_15660	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NUITMVA2_15680	COG3132	Protein of unknown function, DUF480
NUITMVA2_15730	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NUITMVA2_15760	COG1278	Cold shock
NUITMVA2_15810	COG4166	transmembrane transport
NUITMVA2_15820	COG0697	spore germination
NUITMVA2_15840	COG0675	Transposase, IS605 OrfB family
NUITMVA2_15850	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NUITMVA2_15890	COG4166	transmembrane transport
NUITMVA2_15900	COG0622	Phosphoesterase
NUITMVA2_15930	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
NUITMVA2_15940	COG0784	Response regulator, receiver
NUITMVA2_15940	COG0835	chemotaxis
NUITMVA2_15950	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NUITMVA2_15960	COG1815	bacterial-type flagellum-dependent cell motility
NUITMVA2_15990	COG1749	Flagellar hook protein flgE
NUITMVA2_16020	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
NUITMVA2_16030	COG1706	bacterial-type flagellum-dependent cell motility
NUITMVA2_16040	COG1705	Flagellar rod assembly protein muramidase FlgJ
NUITMVA2_16040	COG3951	Flagellar rod assembly protein muramidase FlgJ
NUITMVA2_16070	COG2239	Acts as a magnesium transporter
NUITMVA2_16090	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NUITMVA2_16100	COG2716	regulation of RNA biosynthetic process
NUITMVA2_16150	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NUITMVA2_16160	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NUITMVA2_16170	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NUITMVA2_16180	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NUITMVA2_16220	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NUITMVA2_16240	COG0590	tRNA wobble adenosine to inosine editing
NUITMVA2_16250	COG0573	inorganic phosphate transmembrane transporter activity
NUITMVA2_16260	COG0581	inorganic phosphate transmembrane transporter activity
NUITMVA2_16270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NUITMVA2_16280	COG0704	Plays a role in the regulation of phosphate uptake
NUITMVA2_16290	COG1253	flavin adenine dinucleotide binding
NUITMVA2_16320	COG0531	amino acid
NUITMVA2_16350	COG1126	abc transporter atp-binding protein
NUITMVA2_16360	COG0765	amino acid transport
NUITMVA2_16370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NUITMVA2_16380	COG3706	GGDEF domain
NUITMVA2_16390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NUITMVA2_16430	COG1785	Belongs to the alkaline phosphatase family
NUITMVA2_16440	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NUITMVA2_16450	COG0477	Major facilitator Superfamily
NUITMVA2_16460	COG0123	including yeast histone deacetylase and acetoin utilization protein
NUITMVA2_16480	COG1199	ATP-dependent helicase activity
NUITMVA2_16520	COG1448	Aminotransferase
NUITMVA2_16530	COG0433	COG0433 Predicted ATPase
NUITMVA2_16560	COG2333	competence protein COMEC
NUITMVA2_16560	COG0658	competence protein
NUITMVA2_16570	COG1132	(ABC) transporter
NUITMVA2_16580	COG1663	tetraacyldisaccharide 4'-kinase activity
NUITMVA2_16590	COG2835	tetraacyldisaccharide 4'-kinase activity
NUITMVA2_16600	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NUITMVA2_16610	COG2197	response regulator
NUITMVA2_16620	COG0322	excinuclease ABC activity
NUITMVA2_16660	COG2801	Transposase and inactivated derivatives
NUITMVA2_16680	COG0604	alcohol dehydrogenase
NUITMVA2_16690	COG1309	transcriptional regulator
NUITMVA2_16700	COG2261	transglycosylase associated protein
NUITMVA2_16710	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NUITMVA2_16730	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NUITMVA2_16740	COG0215	cysteine-tRNA ligase activity
NUITMVA2_16790	COG2199	diguanylate cyclase activity
NUITMVA2_16790	COG2203	Gaf domain
NUITMVA2_16860	COG2119	membrane
NUITMVA2_16870	COG0023	Translation Initiation Factor
NUITMVA2_16890	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NUITMVA2_16940	COG4139	cobalamin transport
NUITMVA2_16950	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
NUITMVA2_16960	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NUITMVA2_16970	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NUITMVA2_16980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NUITMVA2_16990	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NUITMVA2_17000	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NUITMVA2_17020	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NUITMVA2_17030	COG0505	Belongs to the CarA family
NUITMVA2_17040	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NUITMVA2_17050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NUITMVA2_17060	COG3706	GGDEF domain
NUITMVA2_17120	COG0513	Belongs to the DEAD box helicase family
NUITMVA2_17140	COG4104	PAAR repeat-containing protein
NUITMVA2_17190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NUITMVA2_17200	COG0765	amino acid transport
NUITMVA2_17210	COG1126	abc transporter atp-binding protein
NUITMVA2_17220	COG0493	'glutamate synthase
NUITMVA2_17230	COG0070	glutamate synthase
NUITMVA2_17230	COG0067	glutamate synthase
NUITMVA2_17230	COG0069	glutamate synthase activity
NUITMVA2_17240	COG1242	4 iron, 4 sulfur cluster binding
NUITMVA2_17340	COG1113	amino acid transport
NUITMVA2_17360	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NUITMVA2_17370	COG0574	Belongs to the PEP-utilizing enzyme family
NUITMVA2_17370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NUITMVA2_17380	COG1119	ATPase activity
NUITMVA2_17410	COG1464	Belongs to the NlpA lipoprotein family
NUITMVA2_17430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NUITMVA2_17440	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NUITMVA2_17460	COG0101	tRNA pseudouridine synthase activity
NUITMVA2_17470	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NUITMVA2_17480	COG0285	dihydrofolate synthase activity
NUITMVA2_17490	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
NUITMVA2_17500	COG2920	part of a sulfur-relay system
NUITMVA2_17510	COG1289	transmembrane transporter activity
NUITMVA2_17520	COG1289	transmembrane transporter activity
NUITMVA2_17530	COG0670	Belongs to the BI1 family
NUITMVA2_17610	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NUITMVA2_17620	COG0840	transmembrane signaling receptor activity
NUITMVA2_17640	COG5001	Diguanylate cyclase
NUITMVA2_17650	COG0564	pseudouridine synthase activity
NUITMVA2_17680	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
NUITMVA2_17700	COG0625	glutathione transferase activity
NUITMVA2_17730	COG0367	asparagine synthase
NUITMVA2_17750	COG0647	UMP catabolic process
NUITMVA2_17760	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NUITMVA2_17770	COG0604	alcohol dehydrogenase
NUITMVA2_17780	COG1902	pentaerythritol trinitrate reductase activity
NUITMVA2_17790	COG1253	flavin adenine dinucleotide binding
NUITMVA2_17810	COG0277	FAD linked oxidase domain protein
NUITMVA2_17810	COG0247	lactate metabolic process
NUITMVA2_17830	COG2050	protein possibly involved in aromatic compounds catabolism
NUITMVA2_17860	COG5001	Diguanylate cyclase
NUITMVA2_17870	COG0583	DNA-binding transcription factor activity
NUITMVA2_17880	COG2814	Major facilitator Superfamily
NUITMVA2_17890	COG2056	Na+-H+ antiporter family
NUITMVA2_17900	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NUITMVA2_17940	COG0483	inositol monophosphate 1-phosphatase activity
NUITMVA2_17960	COG0625	glutathione transferase activity
NUITMVA2_17970	COG0625	glutathione transferase activity
NUITMVA2_17990	COG0601	transmembrane transport
NUITMVA2_18000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NUITMVA2_18010	COG0444	Belongs to the ABC transporter superfamily
NUITMVA2_18020	COG2814	Major facilitator Superfamily
NUITMVA2_18050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NUITMVA2_18060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NUITMVA2_18070	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NUITMVA2_18080	COG0509	glycine decarboxylation via glycine cleavage system
NUITMVA2_18090	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NUITMVA2_18090	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NUITMVA2_18140	COG3634	alkyl hydroperoxide reductase activity
NUITMVA2_18150	COG0450	alkyl hydroperoxide reductase
NUITMVA2_18160	COG0517	IMP dehydrogenase activity
NUITMVA2_18170	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NUITMVA2_18180	COG0343	queuine tRNA-ribosyltransferase activity
NUITMVA2_18190	COG1862	Preprotein translocase
NUITMVA2_18200	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NUITMVA2_18210	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NUITMVA2_18220	COG2897	thiosulfate sulfurtransferase activity
NUITMVA2_18240	COG0826	peptidase U32
NUITMVA2_18250	COG0826	peptidase U32
NUITMVA2_18260	COG3154	lipid carrier protein
NUITMVA2_18290	COG1104	cysteine desulfurase activity
NUITMVA2_18300	COG0822	iron-sulfur transferase activity
NUITMVA2_18320	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NUITMVA2_18330	COG0443	Heat shock 70 kDa protein
NUITMVA2_18340	COG0633	Ferredoxin
NUITMVA2_18360	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NUITMVA2_18370	COG0105	UTP biosynthetic process
NUITMVA2_18380	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NUITMVA2_18400	COG1426	Protein conserved in bacteria
NUITMVA2_18420	COG0124	histidyl-tRNA synthetase
NUITMVA2_18430	COG2976	Protein conserved in bacteria
NUITMVA2_18440	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NUITMVA2_18450	COG1160	GTP binding
NUITMVA2_18460	COG1645	bacterial-type flagellum-dependent swarming motility
NUITMVA2_18470	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NUITMVA2_18480	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NUITMVA2_18480	COG0047	phosphoribosylformylglycinamidine synthase activity
NUITMVA2_18490	COG1007	ATP synthesis coupled electron transport
NUITMVA2_18500	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NUITMVA2_18520	COG0713	ATP synthesis coupled electron transport
NUITMVA2_18530	COG0839	Belongs to the complex I subunit 6 family
NUITMVA2_18540	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NUITMVA2_18550	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NUITMVA2_18560	COG1034	ATP synthesis coupled electron transport
NUITMVA2_18590	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NUITMVA2_18590	COG0649	NAD binding
NUITMVA2_18600	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NUITMVA2_18610	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NUITMVA2_18620	COG1360	Flagellar Motor Protein
NUITMVA2_18630	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NUITMVA2_18650	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NUITMVA2_18670	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
NUITMVA2_18690	COG0724	RNA recognition motif
NUITMVA2_18700	COG4989	oxidoreductase activity
NUITMVA2_18750	COG0745	RESPONSE REGULATOR receiver
NUITMVA2_18760	COG0583	DNA-binding transcription factor activity
NUITMVA2_18780	COG5001	Diguanylate cyclase
NUITMVA2_18780	COG3300	MHYT domain
NUITMVA2_18790	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
NUITMVA2_18800	COG0778	Nitroreductase
NUITMVA2_18860	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NUITMVA2_18870	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NUITMVA2_18880	COG0539	negative regulation of cytoplasmic translation
NUITMVA2_18890	COG0776	regulation of translation
NUITMVA2_18910	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NUITMVA2_18950	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NUITMVA2_18960	COG0602	queuosine metabolic process
NUITMVA2_18970	COG3530	Putative quorum-sensing-regulated virulence factor
NUITMVA2_18980	COG2096	Adenosyltransferase
NUITMVA2_18990	COG2916	Histone family protein nucleoid-structuring protein H-NS
NUITMVA2_19000	COG1757	Na H antiporter
NUITMVA2_19010	COG1435	thymidine kinase activity
NUITMVA2_19040	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NUITMVA2_19060	COG0561	phosphatase activity
NUITMVA2_19080	COG1349	DNA-binding transcription factor activity
NUITMVA2_19090	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NUITMVA2_19100	COG3550	peptidyl-serine autophosphorylation
NUITMVA2_19240	COG3039	Transposase
NUITMVA2_19260	COG2197	response regulator
NUITMVA2_19330	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NUITMVA2_19450	COG0629	single-stranded DNA binding
NUITMVA2_19460	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NUITMVA2_19480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NUITMVA2_19490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUITMVA2_19570	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NUITMVA2_19580	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NUITMVA2_19590	COG1397	ADP-ribosylglycohydrolase
NUITMVA2_19710	COG3039	Transposase
NUITMVA2_19730	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NUITMVA2_19770	COG2801	Transposase and inactivated derivatives
NUITMVA2_19800	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NUITMVA2_19810	COG0626	cystathionine gamma-synthase activity
NUITMVA2_19830	COG2910	NAD(P)H-binding
NUITMVA2_19840	COG0583	DNA-binding transcription factor activity
NUITMVA2_19850	COG1917	Cupin 2, conserved barrel domain protein
NUITMVA2_19850	COG4977	sequence-specific DNA binding
NUITMVA2_19860	COG2200	EAL domain
NUITMVA2_19870	COG3706	GGDEF domain
NUITMVA2_19880	COG4774	siderophore transport
NUITMVA2_19900	COG0583	DNA-binding transcription factor activity
NUITMVA2_19910	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NUITMVA2_19930	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NUITMVA2_19930	COG0617	tRNA 3'-terminal CCA addition
NUITMVA2_19930	COG0517	IMP dehydrogenase activity
NUITMVA2_19940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NUITMVA2_19950	COG3046	protein related to deoxyribodipyrimidine photolyase
NUITMVA2_19970	COG3088	subunit of a heme lyase
NUITMVA2_19970	COG4235	cytochrome complex assembly
NUITMVA2_19980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NUITMVA2_19990	COG1138	Cytochrome C-type biogenesis protein
NUITMVA2_20000	COG3301	Polysulphide reductase, NrfD
NUITMVA2_20010	COG0437	4 iron, 4 sulfur cluster binding
NUITMVA2_20020	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
NUITMVA2_20050	COG0247	lactate metabolic process
NUITMVA2_20060	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
NUITMVA2_20070	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NUITMVA2_20080	COG3012	SEC-C Motif Domain Protein
NUITMVA2_20090	COG0840	transmembrane signaling receptor activity
NUITMVA2_20100	COG1846	Transcriptional regulator
NUITMVA2_20100	COG1940	carbohydrate kinase activity
NUITMVA2_20110	COG3290	protein histidine kinase activity
NUITMVA2_20120	COG4565	transcriptional regulatory protein
NUITMVA2_20150	COG3181	Tripartite tricarboxylate transporter family receptor
NUITMVA2_20160	COG1196	nuclear chromosome segregation
NUITMVA2_20160	COG0741	lytic transglycosylase activity
NUITMVA2_20160	COG0739	heme binding
NUITMVA2_20170	COG0569	domain protein
NUITMVA2_20170	COG2985	domain, Protein
NUITMVA2_20180	COG0556	nucleotide-excision repair
NUITMVA2_20200	COG0586	Pfam SNARE associated Golgi protein
NUITMVA2_20210	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NUITMVA2_20220	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NUITMVA2_20230	COG2186	Transcriptional regulator
NUITMVA2_20240	COG2719	SpoVR family
NUITMVA2_20250	COG2718	Belongs to the UPF0229 family
NUITMVA2_20260	COG2766	serine protein kinase
NUITMVA2_20270	COG0514	ATP-dependent DNA helicase (RecQ)
NUITMVA2_20280	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NUITMVA2_20290	COG0814	amino acid
NUITMVA2_20350	COG0058	SHG alpha-glucan phosphorylase activity
NUITMVA2_20370	COG0471	metal ion transport
NUITMVA2_20380	COG3118	belongs to the thioredoxin family
NUITMVA2_20400	COG1132	(ABC) transporter
NUITMVA2_20410	COG1132	(ABC) transporter
NUITMVA2_20440	COG2501	S4 domain
NUITMVA2_20460	COG3243	poly(R)-hydroxyalkanoic acid synthase
NUITMVA2_20500	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NUITMVA2_20510	COG2329	Antibiotic biosynthesis monooxygenase
NUITMVA2_20560	COG1742	UPF0060 membrane protein
NUITMVA2_20590	COG0513	Belongs to the DEAD box helicase family
NUITMVA2_20600	COG0386	Belongs to the glutathione peroxidase family
NUITMVA2_20620	COG1181	Belongs to the D-alanine--D-alanine ligase family
NUITMVA2_20630	COG3148	PFAM DTW domain containing protein
NUITMVA2_20640	COG0730	response to heat
NUITMVA2_20650	COG0583	DNA-binding transcription factor activity
NUITMVA2_20680	COG3593	DNA synthesis involved in DNA repair
NUITMVA2_20710	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NUITMVA2_20720	COG1011	Hydrolase
NUITMVA2_20730	COG1473	amidohydrolase
NUITMVA2_20740	COG0205	6-phosphofructokinase activity
NUITMVA2_20760	COG1434	Gram-negative-bacterium-type cell wall biogenesis
NUITMVA2_20770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NUITMVA2_20790	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
NUITMVA2_20800	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
NUITMVA2_20850	COG0588	phosphoglycerate mutase activity
NUITMVA2_20870	COG0675	Transposase, IS605 OrfB family
NUITMVA2_20900	COG1280	lysine exporter protein (LysE YggA)
NUITMVA2_20930	COG2824	Alkylphosphonate utilization operon protein PhnA
NUITMVA2_21020	COG2840	Smr protein MutS2
NUITMVA2_21030	COG2890	protein-(glutamine-N5) methyltransferase activity
NUITMVA2_21040	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NUITMVA2_21060	COG0513	Belongs to the DEAD box helicase family
NUITMVA2_21070	COG5654	RES domain protein
NUITMVA2_21090	COG0814	amino acid
NUITMVA2_21100	COG1609	Transcriptional regulator
NUITMVA2_21110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NUITMVA2_21110	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NUITMVA2_21120	COG1105	Belongs to the carbohydrate kinase PfkB family
NUITMVA2_21130	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NUITMVA2_21130	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NUITMVA2_21130	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
NUITMVA2_21140	COG3313	Fe-S protein
NUITMVA2_21150	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
NUITMVA2_21160	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NUITMVA2_21170	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NUITMVA2_21180	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NUITMVA2_21200	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NUITMVA2_21250	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NUITMVA2_21260	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NUITMVA2_21270	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NUITMVA2_21280	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NUITMVA2_21290	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NUITMVA2_21300	COG0072	phenylalanine-tRNA ligase activity
NUITMVA2_21300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NUITMVA2_21310	COG0776	regulation of translation
NUITMVA2_21380	COG0675	Transposase, IS605 OrfB family
NUITMVA2_21410	COG0037	tRNA processing
NUITMVA2_21420	COG0589	response to stress
NUITMVA2_21430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NUITMVA2_21460	COG2217	Heavy metal translocating P-type atpase
NUITMVA2_21480	COG2010	Cytochrome c
NUITMVA2_21510	COG3278	Belongs to the heme-copper respiratory oxidase family
NUITMVA2_21530	COG1956	GAF domain-containing protein
NUITMVA2_21540	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
NUITMVA2_21560	COG0308	aminopeptidase N
NUITMVA2_21580	COG2902	Dehydrogenase
NUITMVA2_21600	COG0167	dihydroorotate dehydrogenase activity
NUITMVA2_21620	COG0116	Belongs to the methyltransferase superfamily
NUITMVA2_21620	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NUITMVA2_21640	COG0488	(ABC) transporter
NUITMVA2_21660	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NUITMVA2_21670	COG1067	ATP-dependent peptidase activity
NUITMVA2_21710	COG5642	Protein of unknown function (DUF2384)
NUITMVA2_21720	COG0583	DNA-binding transcription factor activity
NUITMVA2_21740	COG1979	alcohol dehydrogenase
NUITMVA2_21750	COG0667	Aldo Keto reductase
NUITMVA2_21780	COG2814	Major facilitator Superfamily
NUITMVA2_21800	COG0667	Aldo Keto reductase
NUITMVA2_21820	COG5002	protein histidine kinase activity
NUITMVA2_21870	COG0656	L-ascorbic acid biosynthetic process
NUITMVA2_21880	COG1028	Short-chain dehydrogenase reductase Sdr
NUITMVA2_21910	COG1028	Short-chain dehydrogenase reductase Sdr
NUITMVA2_21950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUITMVA2_22010	COG4115	mRNA cleavage
NUITMVA2_22020	COG2161	toxin-antitoxin pair type II binding
NUITMVA2_22160	COG3547	Transposase (IS116 IS110 IS902 family)
NUITMVA2_22210	COG1695	Transcriptional regulator
NUITMVA2_22250	COG3173	Aminoglycoside phosphotransferase
NUITMVA2_22320	COG1484	DNA-dependent DNA replication
NUITMVA2_22330	COG4584	PFAM Integrase catalytic
NUITMVA2_22460	COG0667	Aldo Keto reductase
NUITMVA2_22470	COG0583	DNA-binding transcription factor activity
NUITMVA2_22480	COG1064	alcohol dehydrogenase
NUITMVA2_22530	COG1609	Transcriptional regulator
NUITMVA2_22550	COG5499	transcription regulator containing HTH domain
NUITMVA2_22640	COG3141	response to X-ray
NUITMVA2_22660	COG2995	paraquat-inducible protein a
NUITMVA2_22670	COG3008	intermembrane lipid transfer
NUITMVA2_22680	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
NUITMVA2_22680	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NUITMVA2_22710	COG0084	hydrolase, TatD family'
NUITMVA2_22720	COG0470	DNA polymerase III
NUITMVA2_22730	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NUITMVA2_22740	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NUITMVA2_22750	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NUITMVA2_22760	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NUITMVA2_22770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NUITMVA2_22780	COG1028	Short-chain dehydrogenase reductase Sdr
NUITMVA2_22800	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NUITMVA2_22810	COG0416	fatty acid biosynthetic process
NUITMVA2_22820	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NUITMVA2_22830	COG1399	metal-binding, possibly nucleic acid-binding protein
NUITMVA2_22860	COG0564	pseudouridine synthase activity
NUITMVA2_22870	COG1530	ribonuclease E activity
NUITMVA2_22880	COG0306	phosphate transporter
NUITMVA2_22890	COG0717	Belongs to the dCTP deaminase family
NUITMVA2_22900	COG0572	uridine kinase
NUITMVA2_22910	COG0489	protein tyrosine kinase activity
NUITMVA2_22920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NUITMVA2_22920	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NUITMVA2_22940	COG1254	Belongs to the acylphosphatase family
NUITMVA2_22950	COG0840	transmembrane signaling receptor activity
NUITMVA2_22960	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NUITMVA2_23000	COG0709	Synthesizes selenophosphate from selenide and ATP
NUITMVA2_23010	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
NUITMVA2_23020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NUITMVA2_23030	COG3437	response regulator, receiver
NUITMVA2_23060	COG2205	protein histidine kinase activity
NUITMVA2_23060	COG5002	protein histidine kinase activity
NUITMVA2_23060	COG0784	Response regulator, receiver
NUITMVA2_23070	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NUITMVA2_23090	COG1643	Atp-dependent helicase
NUITMVA2_23100	COG0517	IMP dehydrogenase activity
NUITMVA2_23100	COG0617	tRNA 3'-terminal CCA addition
NUITMVA2_23100	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NUITMVA2_23110	COG2197	response regulator
NUITMVA2_23120	COG3314	Sporulation integral membrane protein YlbJ
NUITMVA2_23140	COG0583	DNA-binding transcription factor activity
NUITMVA2_23150	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NUITMVA2_23240	COG1074	ATP-dependent DNA helicase activity
NUITMVA2_23280	COG3039	Transposase
NUITMVA2_23300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NUITMVA2_23310	COG2832	Protein of unknown function (DUF454)
NUITMVA2_23320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NUITMVA2_23340	COG0697	spore germination
NUITMVA2_23360	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
NUITMVA2_23370	COG0318	PFAM AMP-dependent synthetase and ligase
NUITMVA2_23380	COG0596	Alpha beta hydrolase
NUITMVA2_23400	COG1214	PFAM Peptidase M22, glycoprotease
NUITMVA2_23410	COG1199	ATP-dependent helicase activity
NUITMVA2_23430	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NUITMVA2_23440	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NUITMVA2_23450	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NUITMVA2_23460	COG0131	Imidazoleglycerol-phosphate dehydratase
NUITMVA2_23460	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NUITMVA2_23470	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NUITMVA2_23480	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NUITMVA2_23490	COG3437	response regulator, receiver
NUITMVA2_23510	COG2205	protein histidine kinase activity
NUITMVA2_23510	COG2198	Histidine kinase
NUITMVA2_23510	COG0784	Response regulator, receiver
NUITMVA2_23520	COG0107	imidazoleglycerol-phosphate synthase activity
NUITMVA2_23530	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NUITMVA2_23530	COG0140	phosphoribosyl-ATP diphosphatase activity
NUITMVA2_23550	COG0318	PFAM AMP-dependent synthetase and ligase
NUITMVA2_23560	COG3134	Outer membrane lipoprotein
NUITMVA2_23590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NUITMVA2_23630	COG4681	YaeQ
NUITMVA2_23650	COG1024	Enoyl-CoA hydratase
NUITMVA2_23650	COG1250	3-hydroxyacyl-CoA dehydrogenase
NUITMVA2_23660	COG0183	Belongs to the thiolase family
NUITMVA2_23670	COG0714	Associated with various cellular activities
NUITMVA2_23740	COG1595	DNA-templated transcription, initiation
NUITMVA2_23760	COG2067	long-chain fatty acid transport protein
NUITMVA2_23770	COG2067	long-chain fatty acid transport protein
NUITMVA2_23780	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
NUITMVA2_23810	COG1301	dicarboxylic acid transport
NUITMVA2_23820	COG3123	guanosine phosphorylase activity
NUITMVA2_23830	COG1760	l-serine dehydratase
NUITMVA2_23840	COG1760	l-serine dehydratase
NUITMVA2_23850	COG2951	lytic endotransglycosylase activity
NUITMVA2_23860	COG3100	YcgL domain-containing protein
NUITMVA2_23870	COG0850	regulation of cytokinetic process
NUITMVA2_23880	COG2894	cell division
NUITMVA2_23890	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NUITMVA2_23900	COG3099	Belongs to the UPF0263 family
NUITMVA2_23910	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NUITMVA2_23940	COG2996	Protein conserved in bacteria
NUITMVA2_23950	COG0675	Transposase, IS605 OrfB family
NUITMVA2_24010	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NUITMVA2_24020	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NUITMVA2_24030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NUITMVA2_24060	COG0307	riboflavin synthase, alpha
NUITMVA2_24080	COG0534	Mate efflux family protein
NUITMVA2_24090	COG0417	DNA replication proofreading
NUITMVA2_24120	COG1560	Kdo2-lipid A biosynthetic process
NUITMVA2_24130	COG1560	Kdo2-lipid A biosynthetic process
NUITMVA2_24150	COG0583	DNA-binding transcription factor activity
NUITMVA2_24160	COG0673	inositol 2-dehydrogenase activity
NUITMVA2_24170	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NUITMVA2_24200	COG0583	DNA-binding transcription factor activity
NUITMVA2_24220	COG2723	6-phospho-beta-galactosidase activity
NUITMVA2_24230	COG0583	DNA-binding transcription factor activity
NUITMVA2_24250	COG0243	molybdopterin cofactor binding
NUITMVA2_24260	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NUITMVA2_24290	COG0583	DNA-binding transcription factor activity
NUITMVA2_24300	COG1879	ABC-type sugar transport system periplasmic component
NUITMVA2_24310	COG1129	ABC transporter
NUITMVA2_24320	COG1172	Belongs to the binding-protein-dependent transport system permease family
NUITMVA2_24330	COG1172	Belongs to the binding-protein-dependent transport system permease family
NUITMVA2_24350	COG0730	response to heat
NUITMVA2_24370	COG1028	Short-chain dehydrogenase reductase Sdr
NUITMVA2_24390	COG1024	Enoyl-CoA hydratase
NUITMVA2_24400	COG1024	Enoyl-CoA hydratase
NUITMVA2_24410	COG1960	acyl-CoA dehydrogenase activity
NUITMVA2_24430	COG1960	acyl-CoA dehydrogenase activity
NUITMVA2_24440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NUITMVA2_24450	COG1024	Enoyl-CoA hydratase
NUITMVA2_24500	COG1584	GPR1 FUN34 yaaH family protein
NUITMVA2_24510	COG3228	Belongs to the MtfA family
NUITMVA2_24530	COG1115	amino acid carrier protein
NUITMVA2_24540	COG1024	Enoyl-CoA hydratase
NUITMVA2_24570	COG3162	membrane
NUITMVA2_24580	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NUITMVA2_24590	COG0488	(ABC) transporter
NUITMVA2_24600	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NUITMVA2_24610	COG0776	regulation of translation
NUITMVA2_24620	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NUITMVA2_24630	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NUITMVA2_24640	COG0740	serine-type endopeptidase activity
NUITMVA2_24650	COG0544	peptidyl-prolyl cis-trans isomerase activity
NUITMVA2_24680	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
NUITMVA2_24690	COG4591	ABC-type transport system involved in lipoprotein release permease component
NUITMVA2_24700	COG1136	(ABC) transporter
NUITMVA2_24710	COG4591	ABC-type transport system involved in lipoprotein release permease component
NUITMVA2_24730	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NUITMVA2_24740	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
NUITMVA2_24760	COG0697	spore germination
NUITMVA2_24780	COG2062	phosphohistidine phosphatase, SixA
NUITMVA2_24820	COG1846	Transcriptional regulator
NUITMVA2_24880	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NUITMVA2_24910	COG4584	PFAM Integrase catalytic
NUITMVA2_24920	COG1484	DNA-dependent DNA replication
NUITMVA2_24980	COG0582	viral genome integration into host DNA
NUITMVA2_24990	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NUITMVA2_24990	COG0519	Catalyzes the synthesis of GMP from XMP
NUITMVA2_25000	COG0516	GMP reductase activity
NUITMVA2_25000	COG0517	IMP dehydrogenase activity
NUITMVA2_25020	COG0366	Alpha amylase catalytic
NUITMVA2_25020	COG1874	Beta-galactosidase
NUITMVA2_25050	COG1570	exodeoxyribonuclease VII activity
NUITMVA2_25070	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NUITMVA2_25080	COG2885	chlorophyll binding
NUITMVA2_25120	COG2154	pterin-4-alpha-carbinolamine dehydratase
NUITMVA2_25140	COG3768	UPF0283 membrane protein
NUITMVA2_25150	COG3106	COG3106 Predicted ATPase
NUITMVA2_25180	COG1842	Phage shock protein A
NUITMVA2_25190	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NUITMVA2_25220	COG4171	peptide transport system, permease
NUITMVA2_25240	COG4172	Belongs to the ABC transporter superfamily
NUITMVA2_25260	COG1609	Transcriptional regulator
NUITMVA2_25270	COG1263	PTS System
NUITMVA2_25270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NUITMVA2_25280	COG2723	6-phospho-beta-galactosidase activity
NUITMVA2_25290	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NUITMVA2_25300	COG1286	toxin biosynthetic process
NUITMVA2_25310	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NUITMVA2_25320	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NUITMVA2_25330	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NUITMVA2_25340	COG1674	ftsk spoiiie
NUITMVA2_25340	COG0531	amino acid
NUITMVA2_25360	COG0686	Belongs to the AlaDH PNT family
NUITMVA2_25370	COG0492	ferredoxin-NADP+ reductase activity
NUITMVA2_25380	COG3706	GGDEF domain
NUITMVA2_25390	COG3134	Outer membrane lipoprotein
NUITMVA2_25400	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NUITMVA2_25410	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NUITMVA2_25420	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NUITMVA2_25430	COG0542	response to heat
NUITMVA2_25440	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NUITMVA2_25450	COG1278	Cold shock
NUITMVA2_25460	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NUITMVA2_25490	COG1944	ATP diphosphatase activity
NUITMVA2_25500	COG2116	formate transmembrane transporter activity
NUITMVA2_25510	COG1882	Formate acetyltransferase
NUITMVA2_25530	COG2801	Transposase and inactivated derivatives
NUITMVA2_25540	COG2983	Belongs to the UPF0260 family
NUITMVA2_25590	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NUITMVA2_25600	COG0045	succinate-CoA ligase (ADP-forming) activity
NUITMVA2_25610	COG0508	dehydrogenase complex catalyzes the overall conversion of
NUITMVA2_25620	COG0567	Dehydrogenase, E1 component
NUITMVA2_25650	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NUITMVA2_25660	COG2009	succinate dehydrogenase
NUITMVA2_25700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NUITMVA2_25710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NUITMVA2_25710	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NUITMVA2_25730	COG3069	C4-dicarboxylate transmembrane transporter activity
NUITMVA2_25760	COG1451	nucleotide metabolic process
NUITMVA2_25790	COG0254	rRNA binding
NUITMVA2_25800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NUITMVA2_25820	COG1172	Belongs to the binding-protein-dependent transport system permease family
NUITMVA2_25830	COG1129	ABC transporter
NUITMVA2_25840	COG1879	ABC-type sugar transport system periplasmic component
NUITMVA2_25850	COG1069	ribulokinase activity
NUITMVA2_25870	COG2160	L-arabinose isomerase activity
NUITMVA2_25880	COG2160	L-arabinose isomerase activity
NUITMVA2_25890	COG0583	DNA-binding transcription factor activity
NUITMVA2_25900	COG0436	Aminotransferase
NUITMVA2_25910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NUITMVA2_25940	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NUITMVA2_25940	COG0392	lysyltransferase activity
NUITMVA2_25950	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NUITMVA2_25970	COG0469	pyruvate kinase activity
NUITMVA2_25990	COG1263	PTS System
NUITMVA2_25990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NUITMVA2_26000	COG1874	Beta-galactosidase
NUITMVA2_26010	COG3867	Arabinogalactan endo-beta-1,4-galactanase
NUITMVA2_26020	COG3833	ABC-type maltose transport systems, permease component
NUITMVA2_26030	COG1175	transmembrane transport
NUITMVA2_26040	COG2182	Extracellular solute-binding protein
NUITMVA2_26090	COG4580	involved in the transport of maltose and maltodextrins
NUITMVA2_26100	COG1609	Transcriptional regulator
NUITMVA2_26110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NUITMVA2_26120	COG1085	galactose-1-phosphate uridylyltransferase
NUITMVA2_26130	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NUITMVA2_26160	COG0582	viral genome integration into host DNA
NUITMVA2_26180	COG2925	Exonuclease
NUITMVA2_26200	COG3345	alpha-galactosidase
NUITMVA2_26210	COG1380	Effector of murein hydrolase LrgA
NUITMVA2_26220	COG1346	cytolysis
NUITMVA2_26230	COG0295	cytidine deaminase activity
NUITMVA2_26240	COG1022	Amp-dependent synthetase and ligase
NUITMVA2_26270	COG0861	Integral membrane protein TerC family
NUITMVA2_26280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NUITMVA2_26290	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NUITMVA2_26300	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NUITMVA2_26380	COG4771	TonB-dependent receptor
NUITMVA2_26390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NUITMVA2_26400	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NUITMVA2_26410	COG1120	ATPase activity
NUITMVA2_26440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NUITMVA2_26470	COG1028	Short-chain dehydrogenase reductase Sdr
NUITMVA2_26480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NUITMVA2_26490	COG3433	isochorismatase activity
NUITMVA2_26490	COG1535	isochorismatase
NUITMVA2_26500	COG1021	2,3-dihydroxybenzoate-AMP ligase
NUITMVA2_26550	COG5001	Diguanylate cyclase
NUITMVA2_26550	COG3300	MHYT domain
NUITMVA2_26580	COG0840	transmembrane signaling receptor activity
NUITMVA2_26590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NUITMVA2_26600	COG3788	relative of glutathione S-transferase, MAPEG superfamily
NUITMVA2_26610	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NUITMVA2_26620	COG0563	adenylate kinase activity
NUITMVA2_26630	COG0326	Molecular chaperone. Has ATPase activity
NUITMVA2_26640	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NUITMVA2_26650	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
NUITMVA2_26660	COG0298	carbon dioxide binding
NUITMVA2_26680	COG0309	Hydrogenase expression formation protein (HypE)
NUITMVA2_26690	COG0375	protein maturation
NUITMVA2_26710	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NUITMVA2_26720	COG3842	ATPase activity
NUITMVA2_26880	COG0740	serine-type endopeptidase activity
NUITMVA2_26920	COG4220	transposase activity
NUITMVA2_26970	COG2135	peptidase activity
NUITMVA2_26980	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NUITMVA2_26990	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NUITMVA2_27070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUITMVA2_27080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NUITMVA2_27120	COG3039	Transposase
NUITMVA2_27140	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
NUITMVA2_27200	COG1846	Transcriptional regulator
NUITMVA2_27300	COG2314	TM2 domain
NUITMVA2_27350	COG0582	viral genome integration into host DNA
NUITMVA2_27360	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
NUITMVA2_27380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NUITMVA2_27410	COG1773	rubredoxin
NUITMVA2_27420	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NUITMVA2_27430	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
NUITMVA2_27440	COG5557	Pfam Polysulphide reductase, NrfD
NUITMVA2_27450	COG0437	4 iron, 4 sulfur cluster binding
NUITMVA2_27460	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
NUITMVA2_27470	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NUITMVA2_27510	COG1484	DNA-dependent DNA replication
NUITMVA2_27520	COG4584	PFAM Integrase catalytic
NUITMVA2_27550	COG3039	Transposase
NUITMVA2_27580	COG1401	restriction endodeoxyribonuclease activity
NUITMVA2_27610	COG0659	secondary active sulfate transmembrane transporter activity
NUITMVA2_27630	COG2308	Evidence 4 Homologs of previously reported genes of
NUITMVA2_27710	COG0672	)-iron permease
NUITMVA2_27760	COG2814	Major facilitator Superfamily
NUITMVA2_27800	COG1136	(ABC) transporter
NUITMVA2_27810	COG0577	efflux transmembrane transporter activity
NUITMVA2_27880	COG1139	Iron-sulfur cluster binding protein
NUITMVA2_27890	COG0247	lactate metabolic process
NUITMVA2_27900	COG1620	l-lactate permease
NUITMVA2_27910	COG0583	DNA-binding transcription factor activity
NUITMVA2_27960	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NUITMVA2_27970	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NUITMVA2_27970	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NUITMVA2_27980	COG0527	aspartate kinase activity
NUITMVA2_28000	COG1368	sulfuric ester hydrolase activity
NUITMVA2_28010	COG0393	Putative heavy-metal-binding
NUITMVA2_28020	COG1252	NADH dehydrogenase
NUITMVA2_28030	COG3150	esterase
NUITMVA2_28040	COG1164	Oligoendopeptidase f
NUITMVA2_28050	COG1164	Oligoendopeptidase f
NUITMVA2_28060	COG2354	Protein conserved in bacteria
NUITMVA2_28110	COG3039	Transposase
NUITMVA2_28130	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NUITMVA2_28140	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NUITMVA2_28210	COG0537	adenosine 5'-monophosphoramidase activity
NUITMVA2_28240	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NUITMVA2_28270	COG1301	dicarboxylic acid transport
NUITMVA2_28290	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NUITMVA2_28300	COG0861	Integral membrane protein TerC family
NUITMVA2_28320	COG0444	Belongs to the ABC transporter superfamily
NUITMVA2_28330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NUITMVA2_28340	COG0601	transmembrane transport
NUITMVA2_28360	COG2095	MarC family integral membrane protein
NUITMVA2_28370	COG1012	belongs to the aldehyde dehydrogenase family
NUITMVA2_28370	COG1454	alcohol dehydrogenase
NUITMVA2_28390	COG3275	phosphorelay sensor kinase activity
NUITMVA2_28400	COG3279	Response regulator of the LytR AlgR family
NUITMVA2_28410	COG1966	Carbon starvation protein
NUITMVA2_28420	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
NUITMVA2_28420	COG3264	Mechanosensitive ion channel
NUITMVA2_28440	COG1566	PFAM secretion protein HlyD family protein
NUITMVA2_28450	COG1061	Type III restriction enzyme res subunit
NUITMVA2_28460	COG2027	D-alanyl-D-alanine carboxypeptidase
NUITMVA2_28470	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NUITMVA2_28490	COG0436	Aminotransferase
NUITMVA2_28500	COG1288	antiporter activity
NUITMVA2_28520	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NUITMVA2_28560	COG0697	spore germination
NUITMVA2_28570	COG0675	Transposase, IS605 OrfB family
NUITMVA2_28580	COG4657	Part of a membrane complex involved in electron transport
NUITMVA2_28590	COG2878	Part of a membrane complex involved in electron transport
NUITMVA2_28610	COG4658	electron transport chain
NUITMVA2_28620	COG4659	FMN binding
NUITMVA2_28630	COG4660	Part of a membrane complex involved in electron transport
NUITMVA2_28640	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NUITMVA2_28650	COG0346	lactoylglutathione lyase activity
NUITMVA2_28700	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NUITMVA2_28720	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NUITMVA2_28790	COG1334	flagellar protein FlaG
NUITMVA2_28800	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NUITMVA2_28830	COG0301	tRNA thio-modification
NUITMVA2_28830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NUITMVA2_28850	COG4953	penicillin-binding protein 1C
NUITMVA2_28860	COG2373	Large extracellular alpha-helical protein
NUITMVA2_28870	COG0446	pyridine nucleotide-disulphide oxidoreductase
NUITMVA2_28890	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NUITMVA2_28910	COG4160	amino acid transport
NUITMVA2_28930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NUITMVA2_28950	COG2431	L-lysine efflux transmembrane transporter activity
NUITMVA2_28960	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NUITMVA2_28970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NUITMVA2_29010	COG1393	Belongs to the ArsC family
NUITMVA2_29030	COG4783	chaperone-mediated protein folding
NUITMVA2_29040	COG0425	Belongs to the sulfur carrier protein TusA family
NUITMVA2_29070	COG0596	Alpha beta hydrolase
NUITMVA2_29090	COG3842	ATPase activity
NUITMVA2_29100	COG3833	ABC-type maltose transport systems, permease component
NUITMVA2_29110	COG1175	transmembrane transport
NUITMVA2_29130	COG3081	Nucleoid-associated protein
NUITMVA2_29140	COG3082	Protein of unknown function (DUF1414)
NUITMVA2_29150	COG3083	sulfuric ester hydrolase activity
NUITMVA2_29160	COG4206	TonB-dependent receptor
NUITMVA2_29180	COG1770	oligopeptidase
NUITMVA2_29230	COG4574	serine-type endopeptidase inhibitor activity
NUITMVA2_29240	COG3085	chromosome segregation
NUITMVA2_29260	COG0287	Prephenate dehydrogenase
NUITMVA2_29260	COG1605	Chorismate mutase
NUITMVA2_29270	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NUITMVA2_29280	COG0584	glycerophosphoryl diester phosphodiesterase
NUITMVA2_29310	COG1349	DNA-binding transcription factor activity
NUITMVA2_29320	COG2271	Major facilitator Superfamily
NUITMVA2_29330	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NUITMVA2_29340	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NUITMVA2_29350	COG0583	DNA-binding transcription factor activity
NUITMVA2_29390	COG0656	L-ascorbic acid biosynthetic process
NUITMVA2_29410	COG2814	Major facilitator Superfamily
NUITMVA2_29420	COG1294	oxidase, subunit
NUITMVA2_29440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NUITMVA2_29460	COG2979	Protein of unknown function (DUF533)
NUITMVA2_29470	COG1607	acyl-coa hydrolase
NUITMVA2_29500	COG0583	DNA-binding transcription factor activity
NUITMVA2_29520	COG2807	transmembrane transport
NUITMVA2_29530	COG1187	pseudouridine synthase activity
NUITMVA2_29540	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NUITMVA2_29560	COG0675	Transposase, IS605 OrfB family
NUITMVA2_29610	COG1061	Type III restriction enzyme res subunit
NUITMVA2_29660	COG1166	arginine decarboxylase activity
NUITMVA2_29670	COG2195	Cleaves the N-terminal amino acid of tripeptides
NUITMVA2_29700	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NUITMVA2_29730	COG0583	DNA-binding transcription factor activity
NUITMVA2_29750	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NUITMVA2_29760	COG0840	transmembrane signaling receptor activity
NUITMVA2_29770	COG0302	gtp cyclohydrolase
NUITMVA2_29790	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NUITMVA2_29820	COG2267	carboxylic ester hydrolase activity
NUITMVA2_29830	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NUITMVA2_29860	COG0314	molybdopterin synthase activity
NUITMVA2_29870	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NUITMVA2_29880	COG0315	cyclic pyranopterin monophosphate synthase activity
NUITMVA2_29890	COG0521	Mo-molybdopterin cofactor biosynthetic process
NUITMVA2_29900	COG3005	denitrification pathway
NUITMVA2_29920	COG0348	domain, Protein
NUITMVA2_29930	COG0437	4 iron, 4 sulfur cluster binding
NUITMVA2_29940	COG0243	molybdopterin cofactor binding
NUITMVA2_29960	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NUITMVA2_29960	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
NUITMVA2_29970	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NUITMVA2_29980	COG3850	Histidine kinase
NUITMVA2_29990	COG2197	response regulator
NUITMVA2_30040	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NUITMVA2_30060	COG0121	glutamine amidotransferase
NUITMVA2_30070	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NUITMVA2_30080	COG1960	acyl-CoA dehydrogenase activity
NUITMVA2_30090	COG0784	Response regulator, receiver
NUITMVA2_30090	COG3437	response regulator, receiver
NUITMVA2_30120	COG0784	Response regulator, receiver
NUITMVA2_30120	COG3437	response regulator, receiver
NUITMVA2_30140	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NUITMVA2_30150	COG0328	RNA-DNA hybrid ribonuclease activity
NUITMVA2_30160	COG2226	methyltransferase
NUITMVA2_30170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NUITMVA2_30180	COG1388	LysM domain
NUITMVA2_30180	COG0741	lytic transglycosylase activity
NUITMVA2_30210	COG1607	acyl-coa hydrolase
NUITMVA2_30240	COG0741	lytic transglycosylase activity
NUITMVA2_30260	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NUITMVA2_30300	COG0729	surface antigen
NUITMVA2_30320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NUITMVA2_30340	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NUITMVA2_30350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NUITMVA2_30360	COG4134	Bacterial extracellular solute-binding protein
NUITMVA2_30380	COG4136	ATPase activity
NUITMVA2_30390	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NUITMVA2_30400	COG2951	lytic endotransglycosylase activity
NUITMVA2_30410	COG1846	Transcriptional regulator
NUITMVA2_30430	COG0033	Phosphoglucomutase
NUITMVA2_30440	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
NUITMVA2_30450	COG0596	Alpha beta hydrolase
NUITMVA2_30480	COG0716	FMN binding
NUITMVA2_30500	COG0735	belongs to the Fur family
NUITMVA2_30510	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NUITMVA2_30530	COG1263	PTS System
NUITMVA2_30530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NUITMVA2_30530	COG2190	(PTS) system
NUITMVA2_30540	COG0363	glucosamine-6-phosphate deaminase activity
NUITMVA2_30550	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NUITMVA2_30560	COG1846	Transcriptional regulator
NUITMVA2_30560	COG1940	carbohydrate kinase activity
NUITMVA2_30600	COG2194	sulfuric ester hydrolase activity
NUITMVA2_30610	COG0217	transcriptional regulatory protein
NUITMVA2_30620	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NUITMVA2_30630	COG1801	Protein of unknown function DUF72
NUITMVA2_30640	COG4106	trans-aconitate 2-methyltransferase activity
NUITMVA2_30650	COG0500	methyltransferase
NUITMVA2_30690	COG0583	DNA-binding transcription factor activity
NUITMVA2_30700	COG0791	NLP P60 protein
NUITMVA2_30730	COG1309	transcriptional regulator
NUITMVA2_30750	COG1454	alcohol dehydrogenase
NUITMVA2_30800	COG0534	Mate efflux family protein
NUITMVA2_30820	COG2841	Protein conserved in bacteria
NUITMVA2_30860	COG0674	pyruvate-flavodoxin oxidoreductase activity
NUITMVA2_30860	COG1013	pyruvate-flavodoxin oxidoreductase activity
NUITMVA2_30860	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NUITMVA2_30860	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NUITMVA2_30880	COG0633	Ferredoxin
NUITMVA2_30880	COG3217	Mosc domain protein beta barrel domain protein
NUITMVA2_30880	COG0633	Ferredoxin
NUITMVA2_30880	COG3217	Mosc domain protein beta barrel domain protein
NUITMVA2_30890	COG0501	Belongs to the peptidase M48B family
NUITMVA2_30900	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NUITMVA2_30910	COG1073	alpha beta
NUITMVA2_30910	COG2226	methyltransferase
NUITMVA2_30920	COG0156	8-amino-7-oxononanoate synthase activity
NUITMVA2_30930	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NUITMVA2_30980	COG0017	Asparaginyl-tRNA synthetase
NUITMVA2_30990	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NUITMVA2_31010	COG1473	amidohydrolase
NUITMVA2_31020	COG3069	C4-dicarboxylate transmembrane transporter activity
NUITMVA2_31050	COG1393	Belongs to the ArsC family
NUITMVA2_31060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NUITMVA2_31070	COG1876	peptidase activity
NUITMVA2_31090	COG3263	regulation of cellular component size
NUITMVA2_31110	COG1280	lysine exporter protein (LysE YggA)
NUITMVA2_31170	COG1957	nucleoside hydrolase
NUITMVA2_31180	COG0564	pseudouridine synthase activity
NUITMVA2_31200	COG1454	alcohol dehydrogenase
NUITMVA2_31210	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NUITMVA2_31220	COG0702	epimerase
NUITMVA2_31230	COG2914	Belongs to the UPF0125 (RnfH) family
NUITMVA2_31240	COG2867	negative regulation of translational initiation
NUITMVA2_31250	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NUITMVA2_31270	COG0800	Aldolase
NUITMVA2_31300	COG3153	acetyltransferase
NUITMVA2_31360	COG0259	pyridoxamine-phosphate oxidase activity
NUITMVA2_31390	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NUITMVA2_31390	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NUITMVA2_31400	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NUITMVA2_31450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NUITMVA2_31460	COG1138	Cytochrome C-type biogenesis protein
NUITMVA2_31470	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
NUITMVA2_31480	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NUITMVA2_31490	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NUITMVA2_31500	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NUITMVA2_31530	COG0835	chemotaxis
NUITMVA2_31550	COG1192	Involved in chromosome partitioning
NUITMVA2_31560	COG1360	Flagellar Motor Protein
NUITMVA2_31570	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NUITMVA2_31580	COG2201	protein-glutamate methylesterase activity
NUITMVA2_31590	COG0784	Response regulator, receiver
NUITMVA2_31590	COG2198	Histidine kinase
NUITMVA2_31590	COG0643	Histidine kinase
NUITMVA2_31600	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
NUITMVA2_31650	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NUITMVA2_31670	COG1684	flagellar biosynthetic protein fliR
NUITMVA2_31780	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NUITMVA2_31800	COG1677	Flagellar hook-basal body complex protein FliE
NUITMVA2_31830	COG1393	Belongs to the ArsC family
NUITMVA2_31840	COG0798	PFAM Bile acid sodium symporter
NUITMVA2_31850	COG0640	Transcriptional regulator
NUITMVA2_31880	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NUITMVA2_31910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NUITMVA2_31920	COG0444	Belongs to the ABC transporter superfamily
NUITMVA2_31930	COG4608	Belongs to the ABC transporter superfamily
NUITMVA2_31950	COG2971	BadF BadG BcrA BcrD
NUITMVA2_31970	COG0840	transmembrane signaling receptor activity
NUITMVA2_32010	COG3724	N-succinylarginine dihydrolase activity
NUITMVA2_32020	COG0616	signal peptide processing
NUITMVA2_32030	COG1028	Short-chain dehydrogenase reductase Sdr
NUITMVA2_32040	COG0583	DNA-binding transcription factor activity
NUITMVA2_32060	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NUITMVA2_32080	COG0583	DNA-binding transcription factor activity
NUITMVA2_32090	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NUITMVA2_32100	COG1881	PFAM PEBP family protein
NUITMVA2_32120	COG3408	Glycogen debranching enzyme
NUITMVA2_32120	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
NUITMVA2_32130	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NUITMVA2_32140	COG0739	heme binding
NUITMVA2_32150	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NUITMVA2_32200	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NUITMVA2_32220	COG3091	SprT-like family
NUITMVA2_32240	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NUITMVA2_32250	COG0189	ligase activity
NUITMVA2_32270	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NUITMVA2_32310	COG1115	amino acid carrier protein
NUITMVA2_32330	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NUITMVA2_32360	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NUITMVA2_32380	COG1301	dicarboxylic acid transport
NUITMVA2_32390	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NUITMVA2_32400	COG2912	Transglutaminase-like superfamily
NUITMVA2_32420	COG2890	protein-(glutamine-N5) methyltransferase activity
NUITMVA2_32430	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NUITMVA2_32440	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NUITMVA2_32450	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NUITMVA2_32460	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NUITMVA2_32470	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NUITMVA2_32480	COG0193	aminoacyl-tRNA hydrolase activity
NUITMVA2_32490	COG0012	GTP binding
NUITMVA2_32500	COG0490	domain, Protein
NUITMVA2_32500	COG0471	metal ion transport
NUITMVA2_32550	COG2814	Major facilitator Superfamily
NUITMVA2_32560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NUITMVA2_32660	COG1012	belongs to the aldehyde dehydrogenase family
NUITMVA2_32680	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NUITMVA2_32710	COG0180	Tryptophanyl-tRNA synthetase
NUITMVA2_32720	COG0546	phosphoglycolate phosphatase activity
NUITMVA2_32730	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NUITMVA2_32740	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NUITMVA2_32760	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NUITMVA2_32770	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NUITMVA2_32830	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NUITMVA2_32840	COG0583	DNA-binding transcription factor activity
NUITMVA2_32870	COG0583	DNA-binding transcription factor activity
NUITMVA2_32890	COG0739	heme binding
NUITMVA2_32910	COG1511	domain protein
NUITMVA2_32910	COG3264	Mechanosensitive ion channel
NUITMVA2_32920	COG0584	glycerophosphoryl diester phosphodiesterase
NUITMVA2_32940	COG1053	succinate dehydrogenase
NUITMVA2_32950	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NUITMVA2_32960	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
NUITMVA2_32970	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
NUITMVA2_33000	COG3214	Protein conserved in bacteria
NUITMVA2_33010	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NUITMVA2_33050	COG0300	oxidoreductase activity
NUITMVA2_33090	COG0189	ligase activity
NUITMVA2_33090	COG4067	protein conserved in archaea
NUITMVA2_33100	COG0516	GMP reductase activity
NUITMVA2_33120	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NUITMVA2_33130	COG2011	ABC-type metal ion transport system permease component
NUITMVA2_33140	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NUITMVA2_33150	COG1464	Belongs to the NlpA lipoprotein family
NUITMVA2_33180	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NUITMVA2_33200	COG2199	diguanylate cyclase activity
NUITMVA2_33220	COG2199	diguanylate cyclase activity
NUITMVA2_33230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NUITMVA2_33260	COG1335	isochorismatase
NUITMVA2_33270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NUITMVA2_33280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NUITMVA2_33290	COG1702	phosphate starvation-inducible protein PhoH
NUITMVA2_33300	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NUITMVA2_33310	COG4535	Mg2 and Co2 transporter CorC
NUITMVA2_33320	COG0815	Transfers the fatty acyl group on membrane lipoproteins
NUITMVA2_33330	COG2888	peptidyl-tyrosine sulfation
NUITMVA2_33340	COG0495	leucyl-tRNA aminoacylation
NUITMVA2_33370	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NUITMVA2_33380	COG0799	negative regulation of ribosome biogenesis
NUITMVA2_33390	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NUITMVA2_33400	COG0768	penicillin binding
NUITMVA2_33410	COG0772	Belongs to the SEDS family
NUITMVA2_33420	COG2951	lytic endotransglycosylase activity
NUITMVA2_33430	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NUITMVA2_33440	COG1686	Belongs to the peptidase S11 family
NUITMVA2_33450	COG2921	Belongs to the UPF0250 family
NUITMVA2_33460	COG0321	lipoyl(octanoyl) transferase activity
NUITMVA2_33470	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NUITMVA2_33490	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NUITMVA2_33520	COG0789	Transcriptional regulator
NUITMVA2_33530	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NUITMVA2_33550	COG1970	mechanosensitive ion channel activity
NUITMVA2_33560	COG4974	Belongs to the 'phage' integrase family
NUITMVA2_33580	COG0312	modulator of DNA gyrase
NUITMVA2_33590	COG0312	modulator of DNA gyrase
NUITMVA2_33620	COG0826	peptidase U32
NUITMVA2_33630	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NUITMVA2_33640	COG1422	Protein of unknown function (DUF1090)
NUITMVA2_33650	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NUITMVA2_33660	COG2211	Major facilitator Superfamily
NUITMVA2_33670	COG1185	polyribonucleotide nucleotidyltransferase activity
NUITMVA2_33680	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NUITMVA2_33690	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NUITMVA2_33700	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NUITMVA2_33710	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NUITMVA2_33720	COG0195	Participates in both transcription termination and antitermination
NUITMVA2_33730	COG0779	Required for maturation of 30S ribosomal subunits
NUITMVA2_33740	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NUITMVA2_33750	COG0149	triose-phosphate isomerase activity
NUITMVA2_33770	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NUITMVA2_33780	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NUITMVA2_33800	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NUITMVA2_33810	COG1534	Rna-binding protein
NUITMVA2_33840	COG1360	Flagellar Motor Protein
NUITMVA2_33850	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NUITMVA2_33860	COG1722	exodeoxyribonuclease VII activity
NUITMVA2_33870	COG0142	geranyltranstransferase activity
NUITMVA2_33880	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NUITMVA2_33890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NUITMVA2_33900	COG0601	transmembrane transport
NUITMVA2_33920	COG4172	Belongs to the ABC transporter superfamily
NUITMVA2_33930	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NUITMVA2_33940	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NUITMVA2_33950	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NUITMVA2_33960	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NUITMVA2_33990	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NUITMVA2_33990	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NUITMVA2_34000	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NUITMVA2_34020	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NUITMVA2_34040	COG3381	protein complex oligomerization
NUITMVA2_34070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NUITMVA2_34080	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NUITMVA2_34090	COG0511	ligase activity, forming carbon-carbon bonds
NUITMVA2_34100	COG0439	Biotin carboxylase
NUITMVA2_34110	COG3924	membrane
NUITMVA2_34120	COG4145	pantothenate transmembrane transporter activity
NUITMVA2_34130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NUITMVA2_34130	COG1263	PTS System
NUITMVA2_34130	COG2190	(PTS) system
NUITMVA2_34140	COG0583	DNA-binding transcription factor activity
NUITMVA2_34150	COG0604	alcohol dehydrogenase
NUITMVA2_34160	COG2264	protein methyltransferase activity
NUITMVA2_34200	COG0778	Nitroreductase
NUITMVA2_34210	COG1902	pentaerythritol trinitrate reductase activity
NUITMVA2_34210	COG0446	pyridine nucleotide-disulphide oxidoreductase
NUITMVA2_34220	COG0616	signal peptide processing
NUITMVA2_34260	COG3139	Protein of unknown function (DUF1315)
NUITMVA2_34270	COG0252	asparaginase activity
NUITMVA2_34280	COG0786	glutamate:sodium symporter activity
NUITMVA2_34300	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NUITMVA2_34310	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NUITMVA2_34320	COG0384	phenazine biosynthesis protein PhzF
NUITMVA2_34330	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NUITMVA2_34340	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NUITMVA2_34350	COG0175	sulfate reduction
NUITMVA2_34360	COG2113	Glycine betaine
NUITMVA2_34370	COG4176	ABC-type proline glycine betaine transport system permease component
NUITMVA2_34380	COG4175	Glycine betaine
NUITMVA2_34400	COG3610	response to peptide
NUITMVA2_34410	COG2966	Psort location CytoplasmicMembrane, score
NUITMVA2_34430	COG0521	Mo-molybdopterin cofactor biosynthetic process
NUITMVA2_34480	COG2313	pseudouridylate synthase activity
NUITMVA2_34490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NUITMVA2_34500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NUITMVA2_34500	COG2146	nitrite reductase [NAD(P)H] activity
NUITMVA2_34510	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NUITMVA2_34510	COG2146	nitrite reductase [NAD(P)H] activity
NUITMVA2_34520	COG1116	anion transmembrane transporter activity
NUITMVA2_34530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NUITMVA2_34540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NUITMVA2_34540	COG1116	anion transmembrane transporter activity
NUITMVA2_34560	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NUITMVA2_34560	COG1648	precorrin-2 dehydrogenase activity
NUITMVA2_34570	COG0243	molybdopterin cofactor binding
NUITMVA2_34620	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NUITMVA2_34650	COG1073	alpha beta
NUITMVA2_34660	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
NUITMVA2_34670	COG2195	Cleaves the N-terminal amino acid of tripeptides
NUITMVA2_34690	COG4608	Belongs to the ABC transporter superfamily
NUITMVA2_34700	COG0444	Belongs to the ABC transporter superfamily
NUITMVA2_34720	COG4239	(ABC) transporter, permease
NUITMVA2_34730	COG4174	ABC transporter (Permease)
NUITMVA2_34740	COG4206	TonB-dependent receptor
NUITMVA2_34760	COG0811	peptide transport
NUITMVA2_34770	COG0811	peptide transport
NUITMVA2_34780	COG0848	biopolymer transport protein
NUITMVA2_34830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NUITMVA2_34840	COG0840	transmembrane signaling receptor activity
NUITMVA2_34860	COG1278	Cold shock
NUITMVA2_34970	COG0629	single-stranded DNA binding
NUITMVA2_34990	COG0270	DNA (cytosine-5-)-methyltransferase activity
NUITMVA2_35070	COG3039	Transposase
NUITMVA2_35180	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NUITMVA2_35240	COG3293	Transposase
NUITMVA2_35660	COG2003	Belongs to the UPF0758 family
NUITMVA2_35760	COG0640	Transcriptional regulator
NUITMVA2_35810	COG0798	PFAM Bile acid sodium symporter
NUITMVA2_35830	COG0431	NADPH-dependent FMN reductase
NUITMVA2_35840	COG1595	DNA-templated transcription, initiation
NUITMVA2_35860	COG3039	Transposase
NUITMVA2_35890	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NUITMVA2_35930	COG3220	belongs to the UPF0276 family
NUITMVA2_36000	COG0785	Cytochrome C biogenesis protein
NUITMVA2_36010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NUITMVA2_36020	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NUITMVA2_36040	COG0659	secondary active sulfate transmembrane transporter activity
NUITMVA2_36050	COG0589	response to stress
NUITMVA2_36070	COG1396	sequence-specific DNA binding
NUITMVA2_36090	COG0582	viral genome integration into host DNA
NUITMVA2_36100	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NUITMVA2_36110	COG1162	GTPase activity
NUITMVA2_36120	COG0688	phosphatidylethanolamine metabolic process
NUITMVA2_36130	COG4628	conserved protein (DUF2132)
NUITMVA2_36170	COG3300	MHYT domain
NUITMVA2_36170	COG5001	Diguanylate cyclase
NUITMVA2_36180	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
NUITMVA2_36210	COG1132	(ABC) transporter
NUITMVA2_36230	COG2897	thiosulfate sulfurtransferase activity
NUITMVA2_36250	COG2066	Belongs to the glutaminase family
NUITMVA2_36260	COG3171	Protein conserved in bacteria
NUITMVA2_36270	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NUITMVA2_36280	COG2234	aminopeptidase activity
NUITMVA2_36280	COG4935	Belongs to the peptidase S8 family
NUITMVA2_36290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NUITMVA2_36300	COG2200	EAL domain
NUITMVA2_36310	COG1090	epimerase
NUITMVA2_36320	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
NUITMVA2_36330	COG4181	ATPase activity
NUITMVA2_36340	COG2755	lipolytic protein G-D-S-L family
NUITMVA2_36350	COG0784	Response regulator, receiver
NUITMVA2_36350	COG0835	chemotaxis
NUITMVA2_36370	COG0516	GMP reductase activity
NUITMVA2_36370	COG0517	IMP dehydrogenase activity
NUITMVA2_36380	COG0488	(ABC) transporter
NUITMVA2_36400	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NUITMVA2_36510	COG0789	Transcriptional regulator
NUITMVA2_36530	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NUITMVA2_36550	COG0668	transmembrane transport
NUITMVA2_36570	COG2731	YhcH YjgK YiaL family protein
NUITMVA2_36590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NUITMVA2_36600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NUITMVA2_36610	COG3227	Zinc metalloprotease (Elastase)
NUITMVA2_36620	COG0583	DNA-binding transcription factor activity
NUITMVA2_36630	COG0477	Major facilitator Superfamily
NUITMVA2_36670	COG2985	domain, Protein
NUITMVA2_36670	COG0569	domain protein
NUITMVA2_36680	COG1272	protein, Hemolysin III
NUITMVA2_36690	COG0076	glutamate decarboxylase activity
NUITMVA2_36700	COG2917	probably involved in intracellular septation
NUITMVA2_36710	COG2350	Protein conserved in bacteria
NUITMVA2_36730	COG1555	photosystem II stabilization
NUITMVA2_36740	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NUITMVA2_36750	COG3104	oligopeptide transport
NUITMVA2_36760	COG0745	RESPONSE REGULATOR receiver
NUITMVA2_36820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUITMVA2_36840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NUITMVA2_36850	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NUITMVA2_36900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NUITMVA2_36910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUITMVA2_37070	COG2801	Transposase and inactivated derivatives
NUITMVA2_37140	COG2003	Belongs to the UPF0758 family
NUITMVA2_37240	COG2003	Belongs to the UPF0758 family
NUITMVA2_37350	COG3311	Transcriptional regulator
NUITMVA2_37380	COG1280	lysine exporter protein (LysE YggA)
NUITMVA2_37390	COG0316	Belongs to the HesB IscA family
NUITMVA2_37410	COG0038	chloride channel
NUITMVA2_37420	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NUITMVA2_37450	COG0671	phosphoesterase, PA-phosphatase related
NUITMVA2_37470	COG0583	DNA-binding transcription factor activity
NUITMVA2_37480	COG2076	Multidrug Resistance protein
NUITMVA2_37500	COG0346	lactoylglutathione lyase activity
NUITMVA2_37510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NUITMVA2_37520	COG1643	Atp-dependent helicase
NUITMVA2_37540	COG1489	DNA binding
NUITMVA2_37550	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NUITMVA2_37560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NUITMVA2_37580	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NUITMVA2_37590	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NUITMVA2_37600	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NUITMVA2_37620	COG0842	Transport permease protein
NUITMVA2_37630	COG1131	(ABC) transporter
NUITMVA2_37660	COG0163	prenyltransferase activity
NUITMVA2_37670	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NUITMVA2_37680	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NUITMVA2_37710	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
NUITMVA2_37740	COG1136	(ABC) transporter
NUITMVA2_37780	COG0840	transmembrane signaling receptor activity
NUITMVA2_37850	COG2801	Transposase and inactivated derivatives
NUITMVA2_37860	COG0529	Catalyzes the synthesis of activated sulfate
NUITMVA2_37870	COG0471	metal ion transport
NUITMVA2_37870	COG3273	potassium ion transport
NUITMVA2_37880	COG2895	sulfate adenylyltransferase (ATP) activity
NUITMVA2_37890	COG0175	sulfate reduction
NUITMVA2_37900	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NUITMVA2_37900	COG1648	precorrin-2 dehydrogenase activity
NUITMVA2_37910	COG0330	HflC and HflK could
NUITMVA2_37920	COG1585	Membrane protein implicated in regulation of membrane protease activity
NUITMVA2_37940	COG0673	inositol 2-dehydrogenase activity
NUITMVA2_37960	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NUITMVA2_37970	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NUITMVA2_37980	COG3036	rescue of stalled ribosome
NUITMVA2_38010	COG0138	bifunctional purine biosynthesis protein purh
NUITMVA2_38020	COG0151	Belongs to the GarS family
NUITMVA2_38070	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NUITMVA2_38080	COG0358	DNA primase activity
NUITMVA2_38090	COG1610	YqeY-like protein
NUITMVA2_38100	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NUITMVA2_38110	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NUITMVA2_38130	COG1388	LysM domain
NUITMVA2_38130	COG4942	peptidase
NUITMVA2_38140	COG1238	metal cluster binding
NUITMVA2_38150	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NUITMVA2_38160	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NUITMVA2_38170	COG0585	pseudouridine synthase activity
NUITMVA2_38190	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NUITMVA2_38200	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NUITMVA2_38210	COG0148	phosphopyruvate hydratase activity
NUITMVA2_38220	COG0504	CTP synthase activity
NUITMVA2_38230	COG3956	TIGRFAM MazG family protein
NUITMVA2_38240	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NUITMVA2_38250	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NUITMVA2_38270	COG4807	Protein conserved in bacteria
NUITMVA2_38280	COG3023	N-Acetylmuramoyl-L-alanine amidase
NUITMVA2_38290	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NUITMVA2_38300	COG1381	Involved in DNA repair and RecF pathway recombination
NUITMVA2_38320	COG0571	ribonuclease III activity
NUITMVA2_38330	COG0681	Belongs to the peptidase S26 family
NUITMVA2_38340	COG0481	GTPase activity
NUITMVA2_38370	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
NUITMVA2_38380	COG1595	DNA-templated transcription, initiation
NUITMVA2_38390	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NUITMVA2_38410	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
NUITMVA2_38430	COG0583	DNA-binding transcription factor activity
NUITMVA2_38500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NUITMVA2_38520	COG0126	phosphoglycerate kinase activity
NUITMVA2_38530	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NUITMVA2_38540	COG1940	carbohydrate kinase activity
NUITMVA2_38550	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NUITMVA2_38560	COG2816	NAD+ diphosphatase activity
NUITMVA2_38570	COG4991	sh3 domain protein
NUITMVA2_38580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NUITMVA2_38610	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NUITMVA2_38620	COG1028	Short-chain dehydrogenase reductase Sdr
NUITMVA2_38650	COG1505	serine-type exopeptidase activity
NUITMVA2_38660	COG1505	serine-type exopeptidase activity
NUITMVA2_38670	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NUITMVA2_38680	COG0765	amino acid transport
NUITMVA2_38690	COG0765	amino acid transport
NUITMVA2_38700	COG1126	abc transporter atp-binding protein
NUITMVA2_38710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NUITMVA2_38720	COG3174	membrane
NUITMVA2_38730	COG0110	maltose O-acetyltransferase activity
NUITMVA2_38810	COG0583	DNA-binding transcription factor activity
NUITMVA2_38820	COG0165	Argininosuccinate lyase
NUITMVA2_38830	COG0137	argininosuccinate synthase activity
NUITMVA2_38850	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NUITMVA2_38860	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NUITMVA2_38880	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NUITMVA2_38900	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NUITMVA2_38970	COG0583	DNA-binding transcription factor activity
NUITMVA2_38980	COG1380	Effector of murein hydrolase LrgA
NUITMVA2_38990	COG1346	cytolysis
NUITMVA2_39000	COG0460	homoserine dehydrogenase
NUITMVA2_39000	COG0527	aspartate kinase activity
NUITMVA2_39010	COG0626	cystathionine gamma-synthase activity
NUITMVA2_39040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NUITMVA2_39050	COG0814	amino acid
NUITMVA2_39060	COG1218	3'(2'),5'-bisphosphate nucleotidase
NUITMVA2_39070	COG0494	nUDIX hydrolase
NUITMVA2_39080	COG1011	Hydrolase
NUITMVA2_39090	COG1902	pentaerythritol trinitrate reductase activity
NUITMVA2_39110	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NUITMVA2_39140	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
NUITMVA2_39160	COG3156	type II secretion system protein K
NUITMVA2_39170	COG4795	General secretion pathway protein
NUITMVA2_39180	COG2165	general secretion pathway protein
NUITMVA2_39200	COG2165	general secretion pathway protein
NUITMVA2_39210	COG1459	type II secretion system
NUITMVA2_39220	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NUITMVA2_39240	COG3031	protein transport across the cell outer membrane
NUITMVA2_39260	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NUITMVA2_39270	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NUITMVA2_39300	COG0456	acetyltransferase
NUITMVA2_39310	COG3133	Outer membrane lipoprotein
NUITMVA2_39320	COG3025	triphosphatase activity
NUITMVA2_39330	COG1392	Phosphate transport regulator
NUITMVA2_39340	COG0306	phosphate transporter
NUITMVA2_39350	COG0617	tRNA 3'-terminal CCA addition
NUITMVA2_39360	COG3267	Type II secretory pathway component ExeA
NUITMVA2_39360	COG3409	Peptidoglycan-binding domain 1 protein
NUITMVA2_39380	COG1194	a g-specific adenine glycosylase
NUITMVA2_39390	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
NUITMVA2_39420	COG3240	lipase activity
NUITMVA2_39440	COG3009	Protein conserved in bacteria
NUITMVA2_39450	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NUITMVA2_39450	COG3008	intermembrane lipid transfer
NUITMVA2_39460	COG2995	paraquat-inducible protein a
NUITMVA2_39480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NUITMVA2_39490	COG2203	Gaf domain
NUITMVA2_39490	COG4251	negative regulation of phosphorylation
NUITMVA2_39490	COG3706	GGDEF domain
NUITMVA2_39490	COG5001	Diguanylate cyclase
NUITMVA2_39500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NUITMVA2_39510	COG2813	Specifically methylates the guanine in position
NUITMVA2_39520	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NUITMVA2_39530	COG0297	glycogen (starch) synthase activity
NUITMVA2_39560	COG1757	Na H antiporter
NUITMVA2_39570	COG0583	DNA-binding transcription factor activity
NUITMVA2_39580	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NUITMVA2_39590	COG3842	ATPase activity
NUITMVA2_39600	COG1176	ABC-type spermidine putrescine transport system, permease component I
NUITMVA2_39610	COG1177	transmembrane transport
NUITMVA2_39620	COG1012	belongs to the aldehyde dehydrogenase family
NUITMVA2_39630	COG0109	protoheme IX farnesyltransferase activity
NUITMVA2_39690	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
NUITMVA2_39710	COG1565	acr, cog1565
NUITMVA2_39710	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NUITMVA2_39720	COG1444	tRNA N-acetyltransferase activity
NUITMVA2_39760	COG1803	Methylglyoxal synthase
NUITMVA2_39790	COG0252	asparaginase activity
NUITMVA2_39830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NUITMVA2_39830	COG1263	PTS System
NUITMVA2_39840	COG0366	Alpha amylase catalytic
NUITMVA2_39850	COG0110	maltose O-acetyltransferase activity
NUITMVA2_39860	COG1522	sequence-specific DNA binding
NUITMVA2_39880	COG5006	permease, DMT superfamily
NUITMVA2_39930	COG3068	Protein conserved in bacteria
NUITMVA2_39950	COG0739	heme binding
NUITMVA2_40000	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
NUITMVA2_40010	COG1121	(ABC) transporter
NUITMVA2_40020	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NUITMVA2_40030	COG0583	DNA-binding transcription factor activity
NUITMVA2_40050	COG1573	uracil-dna glycosylase
NUITMVA2_40060	COG2962	Rard protein
NUITMVA2_40070	COG2827	Endonuclease containing a URI domain
NUITMVA2_40100	COG1842	Phage shock protein A
NUITMVA2_40110	COG0204	Acyl-transferase
NUITMVA2_40150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NUITMVA2_40170	COG0484	heat shock protein binding
NUITMVA2_40270	COG1289	transmembrane transporter activity
NUITMVA2_40280	COG1566	PFAM secretion protein HlyD family protein
NUITMVA2_40310	COG1051	belongs to the nudix hydrolase family
NUITMVA2_40320	COG3150	esterase
NUITMVA2_40340	COG3151	Protein conserved in bacteria
NUITMVA2_40350	COG0494	nUDIX hydrolase
NUITMVA2_40360	COG1538	Outer membrane efflux protein
NUITMVA2_40370	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NUITMVA2_40370	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NUITMVA2_40380	COG1560	Kdo2-lipid A biosynthetic process
NUITMVA2_40410	COG2771	luxR family
NUITMVA2_40420	COG3916	Acyl-homoserine-lactone synthase
NUITMVA2_40430	COG3916	Acyl-homoserine-lactone synthase
NUITMVA2_40450	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
NUITMVA2_40460	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NUITMVA2_40460	COG2213	PTS system mannitol-specific
NUITMVA2_40470	COG0246	Mannitol dehydrogenase
NUITMVA2_40480	COG3722	fumarate hydratase activity
NUITMVA2_40490	COG3263	regulation of cellular component size
NUITMVA2_40530	COG1671	Belongs to the UPF0178 family
NUITMVA2_40560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NUITMVA2_40570	COG0513	Belongs to the DEAD box helicase family
NUITMVA2_40610	COG1575	Belongs to the MenA family. Type 1 subfamily
NUITMVA2_40620	COG1169	isochorismate synthase
NUITMVA2_40630	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NUITMVA2_40640	COG0596	Alpha beta hydrolase
NUITMVA2_40650	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NUITMVA2_40670	COG0318	PFAM AMP-dependent synthetase and ligase
NUITMVA2_40680	COG3291	Pkd domain containing protein
NUITMVA2_40690	COG2949	membrane
NUITMVA2_40700	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NUITMVA2_40720	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NUITMVA2_40780	COG2873	o-acetylhomoserine
NUITMVA2_40800	COG1979	alcohol dehydrogenase
NUITMVA2_40830	COG4221	oxidoreductase activity
NUITMVA2_40870	COG1285	pathogenesis
NUITMVA2_40900	COG1368	sulfuric ester hydrolase activity
NUITMVA2_40910	COG1522	sequence-specific DNA binding
NUITMVA2_40930	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NUITMVA2_40950	COG1058	Belongs to the CinA family
NUITMVA2_40950	COG1546	Belongs to the CinA family
NUITMVA2_40960	COG1988	membrane-bound metal-dependent
NUITMVA2_40990	COG0561	phosphatase activity
NUITMVA2_41000	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NUITMVA2_41020	COG1011	Hydrolase
NUITMVA2_41050	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NUITMVA2_41060	COG0019	diaminopimelate decarboxylase activity
NUITMVA2_41080	COG1965	Belongs to the frataxin family
NUITMVA2_41090	COG0400	carboxylic ester hydrolase activity
NUITMVA2_41100	COG3072	Adenylate cyclase
NUITMVA2_41110	COG0181	hydroxymethylbilane synthase activity
NUITMVA2_41120	COG1587	Uroporphyrinogen-III synthase
NUITMVA2_41130	COG2959	enzyme of heme biosynthesis
NUITMVA2_41140	COG3071	HemY protein
NUITMVA2_41160	COG0312	modulator of DNA gyrase
NUITMVA2_41170	COG3028	Belongs to the UPF0307 family
NUITMVA2_41190	COG2926	Belongs to the UPF0265 family
NUITMVA2_41210	COG1396	sequence-specific DNA binding
NUITMVA2_41220	COG3135	benzoate transporter
NUITMVA2_41270	COG0840	transmembrane signaling receptor activity
NUITMVA2_41280	COG3047	cAMP biosynthetic process
NUITMVA2_41300	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NUITMVA2_41310	COG2197	response regulator
NUITMVA2_41380	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NUITMVA2_41440	COG1396	sequence-specific DNA binding
NUITMVA2_41490	COG1278	Cold shock
NUITMVA2_41550	COG3706	GGDEF domain
NUITMVA2_41560	COG0347	Belongs to the P(II) protein family
NUITMVA2_41570	COG0004	ammonium transporteR
NUITMVA2_41580	COG0346	lactoylglutathione lyase activity
NUITMVA2_41610	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NUITMVA2_41620	COG1074	ATP-dependent DNA helicase activity
NUITMVA2_41630	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NUITMVA2_41640	COG2259	Doxx family
NUITMVA2_41650	COG1741	Belongs to the pirin family
NUITMVA2_41670	COG0583	DNA-binding transcription factor activity
NUITMVA2_41720	COG1175	transmembrane transport
NUITMVA2_41740	COG3842	ATPase activity
NUITMVA2_41800	COG0456	acetyltransferase
NUITMVA2_41810	COG0753	catalase activity
NUITMVA2_41850	COG0494	nUDIX hydrolase
NUITMVA2_41860	COG0628	permease
NUITMVA2_41880	COG2957	Belongs to the agmatine deiminase family
NUITMVA2_41910	COG2957	Belongs to the agmatine deiminase family
NUITMVA2_41920	COG0583	DNA-binding transcription factor activity
NUITMVA2_41950	COG1461	Dihydroxyacetone kinase
NUITMVA2_41960	COG2376	Dihydroxyacetone kinase
NUITMVA2_41970	COG2252	PERMEase
NUITMVA2_41980	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NUITMVA2_41990	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NUITMVA2_42000	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NUITMVA2_42010	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NUITMVA2_42020	COG0049	tRNA binding
NUITMVA2_42030	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NUITMVA2_42040	COG2168	tRNA wobble position uridine thiolation
NUITMVA2_42060	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NUITMVA2_42070	COG0251	oxidation-reduction process
NUITMVA2_42080	COG2964	Protein conserved in bacteria
NUITMVA2_42090	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NUITMVA2_42100	COG0085	RNA polymerase activity
NUITMVA2_42110	COG0222	ribosome binding
NUITMVA2_42120	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NUITMVA2_42130	COG0081	regulation of translation
NUITMVA2_42140	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NUITMVA2_42150	COG0250	Participates in transcription elongation, termination and antitermination
NUITMVA2_42170	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NUITMVA2_42200	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NUITMVA2_42210	COG0569	domain protein
NUITMVA2_42220	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NUITMVA2_42230	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NUITMVA2_42240	COG3005	denitrification pathway
NUITMVA2_42250	COG0243	molybdopterin cofactor binding
NUITMVA2_42320	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NUITMVA2_42340	COG2204	response regulator
NUITMVA2_42360	COG2205	protein histidine kinase activity
NUITMVA2_42390	COG0516	GMP reductase activity
NUITMVA2_42390	COG0517	IMP dehydrogenase activity
NUITMVA2_42410	COG1522	sequence-specific DNA binding
NUITMVA2_42420	COG2502	aspartate--ammonia ligase
NUITMVA2_42450	COG0583	DNA-binding transcription factor activity
NUITMVA2_42460	COG0542	response to heat
NUITMVA2_42480	COG0564	pseudouridine synthase activity
NUITMVA2_42490	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NUITMVA2_42500	COG3681	Belongs to the UPF0597 family
NUITMVA2_42510	COG2964	Protein conserved in bacteria
NUITMVA2_42520	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NUITMVA2_42530	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NUITMVA2_42540	COG1979	alcohol dehydrogenase
NUITMVA2_42550	COG2207	Transcriptional regulator
NUITMVA2_42560	COG3040	lipid binding
NUITMVA2_42600	COG0583	DNA-binding transcription factor activity
NUITMVA2_42630	COG0540	Belongs to the ATCase OTCase family
NUITMVA2_42640	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
NUITMVA2_42650	COG1438	arginine binding
NUITMVA2_42660	COG1288	antiporter activity
NUITMVA2_42670	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NUITMVA2_42750	COG3250	beta-galactosidase activity
NUITMVA2_42770	COG1609	Transcriptional regulator
NUITMVA2_42780	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NUITMVA2_42800	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NUITMVA2_42810	COG2017	converts alpha-aldose to the beta-anomer
NUITMVA2_42820	COG0667	Aldo Keto reductase
NUITMVA2_42830	COG1968	undecaprenyl-diphosphatase activity
NUITMVA2_42840	COG3806	Anti-sigma factor
NUITMVA2_42850	COG1595	DNA-templated transcription, initiation
NUITMVA2_42890	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NUITMVA2_42900	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NUITMVA2_42940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUITMVA2_42950	COG1131	(ABC) transporter
NUITMVA2_42960	COG0842	Transport permease protein
NUITMVA2_42970	COG0842	Transport permease protein
NUITMVA2_42980	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NUITMVA2_43000	COG2116	formate transmembrane transporter activity
NUITMVA2_43010	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NUITMVA2_43010	COG1648	precorrin-2 dehydrogenase activity
NUITMVA2_43020	COG2239	Acts as a magnesium transporter
NUITMVA2_43030	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NUITMVA2_43040	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NUITMVA2_43060	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NUITMVA2_43080	COG0514	ATP-dependent DNA helicase (RecQ)
NUITMVA2_43090	COG2050	protein possibly involved in aromatic compounds catabolism
NUITMVA2_43110	COG2258	MOSC domain
NUITMVA2_43120	COG1177	transmembrane transport
NUITMVA2_43130	COG1176	ABC-type spermidine putrescine transport system, permease component I
NUITMVA2_43140	COG3842	ATPase activity
NUITMVA2_43180	COG0174	glutamine synthetase
NUITMVA2_43220	COG3045	CreA protein
NUITMVA2_43230	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NUITMVA2_43240	COG0443	Heat shock 70 kDa protein
NUITMVA2_43270	COG0366	Alpha amylase catalytic
NUITMVA2_43290	COG4310	Domain of unknown function (DUF2172)
NUITMVA2_43360	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NUITMVA2_43370	COG0745	RESPONSE REGULATOR receiver
NUITMVA2_43380	COG2205	protein histidine kinase activity
NUITMVA2_43400	COG0281	malic enzyme
NUITMVA2_43410	COG0702	epimerase
NUITMVA2_43420	COG0254	rRNA binding
NUITMVA2_43430	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NUITMVA2_43440	COG1309	transcriptional regulator
NUITMVA2_43480	COG0129	dihydroxy-acid dehydratase activity
NUITMVA2_43500	COG3978	acetolactate synthase activity
NUITMVA2_43520	COG0606	chelatase, subunit chli
NUITMVA2_43530	COG0204	Acyl-transferase
NUITMVA2_43540	COG0204	Acyl-transferase
NUITMVA2_43550	COG1683	Conserved Protein
NUITMVA2_43570	COG1335	isochorismatase
NUITMVA2_43590	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NUITMVA2_43600	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NUITMVA2_43620	COG3084	Protein conserved in bacteria
NUITMVA2_43630	COG2203	Gaf domain
NUITMVA2_43630	COG3706	GGDEF domain
NUITMVA2_43630	COG4251	negative regulation of phosphorylation
NUITMVA2_43630	COG5001	Diguanylate cyclase
NUITMVA2_43660	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NUITMVA2_43670	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NUITMVA2_43680	COG1561	YicC-like family, N-terminal region
NUITMVA2_43700	COG1519	Transferase
NUITMVA2_43710	COG0859	PFAM glycosyl transferase family 9
NUITMVA2_43720	COG0463	Glycosyl transferase, family 2
NUITMVA2_43730	COG0859	PFAM glycosyl transferase family 9
NUITMVA2_43740	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NUITMVA2_43750	COG2990	Protein conserved in bacteria
NUITMVA2_43770	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NUITMVA2_43780	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NUITMVA2_43790	COG2003	Belongs to the UPF0758 family
NUITMVA2_43800	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NUITMVA2_43810	COG0756	dUTP diphosphatase activity
NUITMVA2_43820	COG1309	transcriptional regulator
NUITMVA2_43840	COG0668	transmembrane transport
NUITMVA2_43860	COG0166	Belongs to the GPI family
NUITMVA2_43870	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NUITMVA2_43880	COG0583	DNA-binding transcription factor activity
NUITMVA2_43900	COG1042	CoA-binding domain protein
NUITMVA2_43900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NUITMVA2_43900	COG0045	succinate-CoA ligase (ADP-forming) activity
NUITMVA2_43910	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
NUITMVA2_43920	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NUITMVA2_43930	COG1739	Uncharacterized protein family UPF0029
NUITMVA2_43940	COG0006	proline dipeptidase activity
NUITMVA2_43950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NUITMVA2_43960	COG1250	3-hydroxyacyl-CoA dehydrogenase
NUITMVA2_43960	COG1024	Enoyl-CoA hydratase
NUITMVA2_43970	COG0183	Belongs to the thiolase family
NUITMVA2_44020	COG0425	Belongs to the sulfur carrier protein TusA family
NUITMVA2_44030	COG0251	oxidation-reduction process
NUITMVA2_44040	COG2885	chlorophyll binding
NUITMVA2_44060	COG1335	isochorismatase
NUITMVA2_44070	COG2818	Glycosylase
NUITMVA2_44080	COG0752	glycyl-tRNA synthetase alpha subunit
NUITMVA2_44090	COG0751	glycine-tRNA ligase activity
NUITMVA2_44120	COG3604	Transcriptional regulator
NUITMVA2_44130	COG0426	domain, Protein
NUITMVA2_44130	COG1773	rubredoxin
NUITMVA2_44140	COG0446	pyridine nucleotide-disulphide oxidoreductase
NUITMVA2_44160	COG0348	domain, Protein
NUITMVA2_44170	COG3033	Beta-eliminating lyase
NUITMVA2_44180	COG0814	amino acid
NUITMVA2_44190	COG0814	amino acid
NUITMVA2_44230	COG4251	negative regulation of phosphorylation
NUITMVA2_44230	COG5001	Diguanylate cyclase
NUITMVA2_44230	COG2203	Gaf domain
NUITMVA2_44230	COG3706	GGDEF domain
NUITMVA2_44250	COG1609	Transcriptional regulator
NUITMVA2_44330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NUITMVA2_44360	COG2960	long-chain fatty acid transporting porin activity
NUITMVA2_44380	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NUITMVA2_44410	COG3118	belongs to the thioredoxin family
NUITMVA2_44420	COG0513	Belongs to the DEAD box helicase family
NUITMVA2_44430	COG0248	Ppx GppA phosphatase
NUITMVA2_44450	COG0742	ribosomal rna small subunit methyltransferase
NUITMVA2_44490	COG0084	hydrolase, TatD family'
NUITMVA2_44500	COG0805	protein transport
NUITMVA2_44510	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NUITMVA2_44520	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NUITMVA2_44530	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NUITMVA2_44540	COG3165	ubiquinone biosynthetic process from chorismate
NUITMVA2_44560	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NUITMVA2_44570	COG0402	S-adenosylhomocysteine deaminase activity
NUITMVA2_44590	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NUITMVA2_44600	COG0848	biopolymer transport protein
NUITMVA2_44610	COG0811	peptide transport
NUITMVA2_44620	COG0811	peptide transport
NUITMVA2_44640	COG2771	luxR family
NUITMVA2_44650	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NUITMVA2_44660	COG1349	DNA-binding transcription factor activity
NUITMVA2_44670	COG0745	RESPONSE REGULATOR receiver
NUITMVA2_44680	COG2205	protein histidine kinase activity
NUITMVA2_44700	COG4452	Inner membrane protein CreD
NUITMVA2_44710	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NUITMVA2_44720	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NUITMVA2_44730	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NUITMVA2_44740	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NUITMVA2_44750	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NUITMVA2_44760	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NUITMVA2_44770	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NUITMVA2_44790	COG0356	it plays a direct role in the translocation of protons across the membrane
NUITMVA2_44810	COG1475	DNA binding
NUITMVA2_44820	COG1192	Involved in chromosome partitioning
NUITMVA2_44830	COG0357	Ribosomal RNA small subunit methyltransferase G
NUITMVA2_44840	COG0445	tRNA wobble uridine modification
NUITMVA2_44850	COG0716	FMN binding
NUITMVA2_44870	COG4615	Cyclic peptide transporter
NUITMVA2_44880	COG1120	ATPase activity
NUITMVA2_44890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NUITMVA2_44910	COG3550	peptidyl-serine autophosphorylation
NUITMVA2_44960	COG0732	type I restriction modification DNA specificity domain
NUITMVA2_44980	COG4644	lycopene metabolic process
NUITMVA2_44990	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NUITMVA2_45070	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NUITMVA2_45080	COG3041	Addiction module toxin RelE StbE family
NUITMVA2_45110	COG3328	transposase activity
NUITMVA2_45120	COG3039	Transposase
NUITMVA2_45140	COG4251	negative regulation of phosphorylation
NUITMVA2_45170	COG0789	Transcriptional regulator
NUITMVA2_45190	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NUITMVA2_45310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NUITMVA2_45340	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NUITMVA2_45350	COG3263	regulation of cellular component size
NUITMVA2_45410	COG0789	Transcriptional regulator
NUITMVA2_45580	COG1937	Protein conserved in bacteria
NUITMVA2_45590	COG1230	cation diffusion facilitator family transporter
NUITMVA2_45600	COG0640	Transcriptional regulator
NUITMVA2_45620	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NUITMVA2_45650	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NUITMVA2_45670	COG0583	DNA-binding transcription factor activity
NUITMVA2_45690	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NUITMVA2_45700	COG0625	glutathione transferase activity
NUITMVA2_45840	COG3385	transposase activity
NUITMVA2_45880	COG3041	Addiction module toxin RelE StbE family
NUITMVA2_45890	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NUITMVA2_45910	COG1028	Short-chain dehydrogenase reductase Sdr
NUITMVA2_46000	COG4974	Belongs to the 'phage' integrase family
NUITMVA2_46010	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NUITMVA2_46020	COG0706	membrane insertase activity
NUITMVA2_46030	COG0594	ribonuclease P activity
NUITMVA2_46040	COG1126	abc transporter atp-binding protein