locus-tag	class	description
L1871_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
L1871_00010	COG0592	DNA-directed DNA polymerase activity
L1871_00020	COG0187	DNA topoisomerase II activity
L1871_00025	COG2207	Transcriptional regulator
L1871_00030	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
L1871_00035	COG0071	Belongs to the small heat shock protein (HSP20) family
L1871_00040	COG0071	Belongs to the small heat shock protein (HSP20) family
L1871_00045	COG3977	Valine--pyruvate aminotransferase
L1871_00060	COG2814	Major facilitator Superfamily
L1871_00065	COG0745	RESPONSE REGULATOR receiver
L1871_00070	COG2205	protein histidine kinase activity
L1871_00090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L1871_00095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L1871_00095	COG4191	Histidine kinase
L1871_00100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L1871_00105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L1871_00110	COG1309	transcriptional regulator
L1871_00140	COG0561	phosphatase activity
L1871_00145	COG2267	carboxylic ester hydrolase activity
L1871_00150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L1871_00155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L1871_00160	COG1758	RNA polymerase activity
L1871_00170	COG0859	PFAM glycosyl transferase family 9
L1871_00175	COG3642	lipopolysaccharide core region biosynthetic process
L1871_00215	COG0589	response to stress
L1871_00220	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
L1871_00225	COG3706	GGDEF domain
L1871_00230	COG1528	Iron-storage protein
L1871_00235	COG2081	HI0933 family
L1871_00240	COG2223	nitrite transmembrane transporter activity
L1871_00245	COG1280	lysine exporter protein (LysE YggA)
L1871_00255	COG0456	acetyltransferase
L1871_00260	COG3039	Transposase
L1871_00265	COG3039	Transposase
L1871_00275	COG2205	protein histidine kinase activity
L1871_00275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L1871_00280	COG2205	protein histidine kinase activity
L1871_00280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L1871_00285	COG3275	phosphorelay sensor kinase activity
L1871_00290	COG3279	Response regulator of the LytR AlgR family
L1871_00295	COG2223	nitrite transmembrane transporter activity
L1871_00300	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L1871_00305	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
L1871_00315	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L1871_00350	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L1871_00355	COG2166	iron-sulfur cluster assembly
L1871_00360	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L1871_00380	COG1063	alcohol dehydrogenase
L1871_00385	COG0156	8-amino-7-oxononanoate synthase activity
L1871_00395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L1871_00405	COG3307	-O-antigen
L1871_00440	COG1609	Transcriptional regulator
L1871_00455	COG1580	Controls the rotational direction of flagella during chemotaxis
L1871_00460	COG3161	chorismate lyase activity
L1871_00465	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
L1871_00470	COG2937	Belongs to the GPAT DAPAT family
L1871_00475	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L1871_00490	COG0534	Mate efflux family protein
L1871_00495	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L1871_00500	COG2205	protein histidine kinase activity
L1871_00505	COG0745	RESPONSE REGULATOR receiver
L1871_00515	COG1045	serine acetyltransferase
L1871_00525	COG3074	FtsZ-dependent cytokinesis
L1871_00530	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
L1871_00535	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L1871_00535	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L1871_00540	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L1871_00575	COG1609	Transcriptional regulator
L1871_00580	COG3250	beta-galactosidase activity
L1871_00585	COG2731	YhcH YjgK YiaL family protein
L1871_00590	COG0531	amino acid
L1871_00595	COG0385	Bile acid
L1871_00600	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L1871_00625	COG0583	DNA-binding transcription factor activity
L1871_00640	COG1079	Belongs to the binding-protein-dependent transport system permease family
L1871_00645	COG4603	Belongs to the binding-protein-dependent transport system permease family
L1871_00650	COG3845	ABC transporter
L1871_00655	COG1744	ABC transporter substrate-binding protein PnrA-like
L1871_00670	COG0210	DNA helicase
L1871_00675	COG3039	Transposase
L1871_00710	COG0583	DNA-binding transcription factor activity
L1871_00755	COG0583	DNA-binding transcription factor activity
L1871_00770	COG1280	lysine exporter protein (LysE YggA)
L1871_00780	COG2962	Rard protein
L1871_00790	COG1012	belongs to the aldehyde dehydrogenase family
L1871_00795	COG1396	sequence-specific DNA binding
L1871_00800	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
L1871_00810	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L1871_00810	COG0519	Catalyzes the synthesis of GMP from XMP
L1871_00820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L1871_00840	COG1322	Protein conserved in bacteria
L1871_00845	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L1871_00850	COG0569	domain protein
L1871_00855	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
L1871_00855	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
L1871_00860	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
L1871_00865	COG0242	peptide deformylase activity
L1871_00875	COG0758	DNA mediated transformation
L1871_00880	COG2922	Belongs to the Smg family
L1871_00885	COG0551	DNA topoisomerase type I activity
L1871_00890	COG0009	L-threonylcarbamoyladenylate synthase
L1871_00895	COG0408	coproporphyrinogen oxidase activity
L1871_00900	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
L1871_00905	COG0218	Necessary for normal cell division and for the maintenance of normal septation
L1871_00915	COG3078	GTPase activator activity
L1871_00925	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L1871_00930	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L1871_00940	COG3852	Histidine kinase
L1871_00950	COG0174	glutamine synthetase
L1871_00955	COG1217	gtp-binding protein TYPA
L1871_00960	COG1295	ribonuclease BN
L1871_00965	COG1490	D-aminoacyl-tRNA deacylase activity
L1871_00975	COG0456	acetyltransferase
L1871_00985	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L1871_00990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L1871_00995	COG2610	gluconate transmembrane transporter activity
L1871_01000	COG3265	gluconokinase activity
L1871_01005	COG0129	dihydroxy-acid dehydratase activity
L1871_01010	COG0800	Aldolase
L1871_01025	COG1609	Transcriptional regulator
L1871_01035	COG4942	peptidase
L1871_01040	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
L1871_01045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L1871_01050	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
L1871_01055	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
L1871_01060	COG0316	Belongs to the HesB IscA family
L1871_01060	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
L1871_01065	COG1040	competence protein
L1871_01070	COG0596	Alpha beta hydrolase
L1871_01085	COG2183	response to ionizing radiation
L1871_01090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L1871_01100	COG2205	protein histidine kinase activity
L1871_01110	COG0051	transcription antitermination factor activity, RNA binding
L1871_01115	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
L1871_01120	COG0088	Forms part of the polypeptide exit tunnel
L1871_01125	COG0089	rRNA binding
L1871_01130	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
L1871_01135	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
L1871_01140	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
L1871_01145	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
L1871_01150	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
L1871_01155	COG0255	Belongs to the universal ribosomal protein uL29 family
L1871_01160	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
L1871_01165	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
L1871_01170	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
L1871_01175	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
L1871_01180	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
L1871_01185	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
L1871_01190	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
L1871_01195	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
L1871_01200	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
L1871_01205	COG1841	ribosomal large subunit assembly
L1871_01210	COG0200	Binds to the 23S rRNA
L1871_01215	COG0201	protein transport
L1871_01220	COG0257	Belongs to the bacterial ribosomal protein bL36 family
L1871_01225	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
L1871_01230	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
L1871_01235	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
L1871_01240	COG0202	RNA polymerase activity
L1871_01245	COG0203	ribosomal protein L17
L1871_01315	COG2249	NAD(P)H dehydrogenase (quinone) activity
L1871_01320	COG0583	DNA-binding transcription factor activity
L1871_01325	COG4221	oxidoreductase activity
L1871_01340	COG1770	oligopeptidase
L1871_01345	COG2358	TRAP transporter, solute receptor (TAXI family
L1871_01360	COG3714	YhhN family
L1871_01375	COG0583	DNA-binding transcription factor activity
L1871_01385	COG1301	dicarboxylic acid transport
L1871_01395	COG2095	MarC family integral membrane protein
L1871_01405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
L1871_01415	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
L1871_01425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L1871_01450	COG0742	ribosomal rna small subunit methyltransferase
L1871_01455	COG0552	protein localization to endoplasmic reticulum
L1871_01460	COG2884	Cell division ATP-binding protein ftsE
L1871_01465	COG2177	Part of the ABC transporter FtsEX involved in
L1871_01475	COG0288	reversible hydration of carbon dioxide
L1871_01480	COG2188	Transcriptional regulator
L1871_01485	COG1228	amidohydrolase
L1871_01490	COG0010	Belongs to the arginase family
L1871_01495	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
L1871_01500	COG2986	histidine ammonia-lyase
L1871_01505	COG0387	Pfam Sodium calcium exchanger
L1871_01510	COG2200	EAL domain
L1871_01565	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L1871_01570	COG1459	type II secretion system
L1871_01615	COG1077	Cell shape determining protein MreB Mrl
L1871_01620	COG1792	Involved in formation and maintenance of cell shape
L1871_01625	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
L1871_01630	COG0424	maF-like protein
L1871_01635	COG1530	ribonuclease E activity
L1871_01640	COG3164	Protein of unknown function
L1871_01645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L1871_01650	COG0312	modulator of DNA gyrase
L1871_01665	COG0477	Major facilitator Superfamily
L1871_01675	COG2321	neutral zinc metallopeptidase
L1871_01710	COG0189	ligase activity
L1871_01720	COG0642	Histidine kinase
L1871_01725	COG0745	RESPONSE REGULATOR receiver
L1871_01740	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
L1871_01745	COG0352	thiamine-phosphate diphosphorylase activity
L1871_01750	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
L1871_01760	COG2022	thiamine diphosphate biosynthetic process
L1871_01765	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
L1871_01770	COG2801	Transposase and inactivated derivatives
L1871_01815	COG3932	Exopolysaccharide synthesis, ExoD
L1871_01830	COG1733	regulation of RNA biosynthetic process
L1871_01835	COG0456	acetyltransferase
L1871_01860	COG2226	methyltransferase
L1871_01870	COG1494	fructose-1,6-bisphosphatase
L1871_01880	COG3071	HemY protein
L1871_01885	COG2959	enzyme of heme biosynthesis
L1871_01895	COG0181	hydroxymethylbilane synthase activity
L1871_01900	COG3072	Adenylate cyclase
L1871_01905	COG0400	carboxylic ester hydrolase activity
L1871_01910	COG1965	Belongs to the frataxin family
L1871_01920	COG0019	diaminopimelate decarboxylase activity
L1871_01925	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
L1871_01940	COG1011	Hydrolase
L1871_01950	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
L1871_01955	COG0561	phosphatase activity
L1871_01965	COG1988	membrane-bound metal-dependent
L1871_01970	COG1058	Belongs to the CinA family
L1871_01970	COG1546	Belongs to the CinA family
L1871_01980	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
L1871_01990	COG1522	sequence-specific DNA binding
L1871_01995	COG1368	sulfuric ester hydrolase activity
L1871_02010	COG1285	pathogenesis
L1871_02030	COG4221	oxidoreductase activity
L1871_02045	COG1979	alcohol dehydrogenase
L1871_02055	COG2873	o-acetylhomoserine
L1871_02065	COG4533	DNA binding
L1871_02085	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
L1871_02095	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L1871_02100	COG2949	membrane
L1871_02105	COG3291	Pkd domain containing protein
L1871_02110	COG0318	PFAM AMP-dependent synthetase and ligase
L1871_02120	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
L1871_02125	COG0596	Alpha beta hydrolase
L1871_02130	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
L1871_02135	COG1169	isochorismate synthase
L1871_02140	COG1575	Belongs to the MenA family. Type 1 subfamily
L1871_02160	COG0513	Belongs to the DEAD box helicase family
L1871_02165	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L1871_02180	COG1671	Belongs to the UPF0178 family
L1871_02200	COG3263	regulation of cellular component size
L1871_02205	COG3722	fumarate hydratase activity
L1871_02210	COG0246	Mannitol dehydrogenase
L1871_02215	COG2213	PTS system mannitol-specific
L1871_02215	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
L1871_02220	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
L1871_02230	COG3916	Acyl-homoserine-lactone synthase
L1871_02235	COG2771	luxR family
L1871_02250	COG1560	Kdo2-lipid A biosynthetic process
L1871_02255	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
L1871_02255	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
L1871_02260	COG1538	Outer membrane efflux protein
L1871_02265	COG0494	nUDIX hydrolase
L1871_02270	COG3151	Protein conserved in bacteria
L1871_02280	COG3150	esterase
L1871_02285	COG1051	belongs to the nudix hydrolase family
L1871_02300	COG1566	PFAM secretion protein HlyD family protein
L1871_02305	COG1289	transmembrane transporter activity
L1871_02320	COG3039	Transposase
L1871_02360	COG0484	heat shock protein binding
L1871_02370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L1871_02390	COG0204	Acyl-transferase
L1871_02395	COG1842	Phage shock protein A
L1871_02410	COG2827	Endonuclease containing a URI domain
L1871_02415	COG2962	Rard protein
L1871_02420	COG1573	uracil-dna glycosylase
L1871_02430	COG0583	DNA-binding transcription factor activity
L1871_02435	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L1871_02440	COG1121	(ABC) transporter
L1871_02445	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
L1871_02465	COG0739	heme binding
L1871_02475	COG3068	Protein conserved in bacteria
L1871_02500	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
L1871_02510	COG1546	Belongs to the CinA family
L1871_02515	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
L1871_02520	COG2137	regulation of response to DNA damage stimulus
L1871_02525	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
L1871_02530	COG0527	aspartate kinase activity
L1871_02535	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
L1871_02570	COG1686	Belongs to the peptidase S11 family
L1871_02580	COG0586	Pfam SNARE associated Golgi protein
L1871_02585	COG1253	flavin adenine dinucleotide binding
L1871_02590	COG0525	valine-tRNA ligase activity
L1871_02600	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
L1871_02605	COG0795	lipopolysaccharide-transporting ATPase activity
L1871_02610	COG0795	lipopolysaccharide-transporting ATPase activity
L1871_02630	COG0004	ammonium transporteR
L1871_02635	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
L1871_02650	COG2165	general secretion pathway protein
L1871_02655	COG0084	hydrolase, TatD family'
L1871_02660	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L1871_02670	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
L1871_02675	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
L1871_02680	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
L1871_02685	COG0813	purine-nucleoside phosphorylase activity
L1871_02705	COG0560	Phosphoserine phosphatase
L1871_02720	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
L1871_02730	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
L1871_02735	COG0776	regulation of translation
L1871_02755	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L1871_02760	COG0735	belongs to the Fur family
L1871_02780	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
L1871_02785	COG0513	Belongs to the DEAD box helicase family
L1871_02790	COG3022	response to hydroperoxide
L1871_02805	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
L1871_02810	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L1871_02815	COG0762	integral membrane protein
L1871_02820	COG1872	DUF167
L1871_02840	COG3112	Uncharacterised protein family (UPF0231)
L1871_02845	COG3835	regulator
L1871_02850	COG2610	gluconate transmembrane transporter activity
L1871_02855	COG1929	Belongs to the glycerate kinase type-1 family
L1871_02870	COG0583	DNA-binding transcription factor activity
L1871_02875	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L1871_02890	COG0347	Belongs to the P(II) protein family
L1871_02905	COG3842	ATPase activity
L1871_02910	COG2837	iron assimilation
L1871_02915	COG1438	arginine binding
L1871_02920	COG1126	abc transporter atp-binding protein
L1871_02925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L1871_02930	COG4215	(ABC) transporter
L1871_02935	COG4160	amino acid transport
L1871_02940	COG0039	L-malate dehydrogenase activity
L1871_02945	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
L1871_02950	COG1017	nitric oxide dioxygenase activity
L1871_02950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L1871_02960	COG4536	flavin adenine dinucleotide binding
L1871_02965	COG4137	Cytochrome C assembly protein
L1871_02970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L1871_02975	COG0228	four-way junction DNA binding
L1871_02980	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
L1871_02985	COG0336	Belongs to the RNA methyltransferase TrmD family
L1871_02990	COG0335	large ribosomal subunit rRNA binding
L1871_03000	COG3066	DNA modification
L1871_03005	COG1051	belongs to the nudix hydrolase family
L1871_03015	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
L1871_03020	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
L1871_03025	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L1871_03035	COG0583	DNA-binding transcription factor activity
L1871_03040	COG0640	Transcriptional regulator
L1871_03045	COG0268	Binds directly to 16S ribosomal RNA
L1871_03050	COG0728	peptidoglycan biosynthetic process
L1871_03055	COG0196	riboflavin kinase activity
L1871_03060	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
L1871_03065	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
L1871_03070	COG1047	Peptidyl-prolyl cis-trans
L1871_03075	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
L1871_03115	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
L1871_03115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L1871_03130	COG1854	S-ribosylhomocysteine lyase activity
L1871_03135	COG3706	GGDEF domain
L1871_03140	COG0557	exoribonuclease II activity
L1871_03145	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L1871_03155	COG2153	protein acetylation
L1871_03165	COG1914	H( )-stimulated, divalent metal cation uptake system
L1871_03170	COG0360	Binds together with S18 to 16S ribosomal RNA
L1871_03175	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
L1871_03180	COG0359	binds to the 23S rRNA
L1871_03220	COG1238	metal cluster binding
L1871_03225	COG0612	Peptidase, M16
L1871_03230	COG2918	glutathione biosynthetic process
L1871_03235	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
L1871_03240	COG1027	Aspartate ammonia-lyase
L1871_03245	COG3030	protein affecting phage T7 exclusion by the F plasmid
L1871_03250	COG0534	Mate efflux family protein
L1871_03255	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
L1871_03260	COG0459	protein refolding
L1871_03280	COG0564	pseudouridine synthase activity
L1871_03285	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
L1871_03335	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
L1871_03345	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
L1871_03350	COG4208	sulfate ABC transporter
L1871_03355	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
L1871_03360	COG0583	DNA-binding transcription factor activity
L1871_03365	COG3397	chitin binding
L1871_03370	COG0840	transmembrane signaling receptor activity
L1871_03395	COG1328	CTP reductase activity
L1871_03400	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
L1871_03420	COG1448	Aminotransferase
L1871_03455	COG0513	Belongs to the DEAD box helicase family
L1871_03460	COG0840	transmembrane signaling receptor activity
L1871_03470	COG4166	transmembrane transport
L1871_03485	COG1024	Enoyl-CoA hydratase
L1871_03500	COG4221	oxidoreductase activity
L1871_03505	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L1871_03510	COG0442	prolyl-tRNA aminoacylation
L1871_03520	COG0632	four-way junction helicase activity
L1871_03525	COG2255	four-way junction helicase activity
L1871_03535	COG1271	oxidase subunit
L1871_03540	COG1294	oxidase, subunit
L1871_03545	COG4890	Cyd operon protein YbgT
L1871_03550	COG3790	cyd operon protein YbgE
L1871_03555	COG0824	Thioesterase
L1871_03560	COG0811	peptide transport
L1871_03575	COG0823	Involved in the tonB-independent uptake of proteins
L1871_03580	COG2885	chlorophyll binding
L1871_03585	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
L1871_03665	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
L1871_03675	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L1871_03680	COG1640	4-alpha-glucanotransferase
L1871_03685	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
L1871_03715	COG2130	NADP-dependent
L1871_03720	COG1846	Transcriptional regulator
L1871_03750	COG0561	phosphatase activity
L1871_03765	COG0733	neurotransmitter:sodium symporter activity
L1871_03770	COG0733	neurotransmitter:sodium symporter activity
L1871_03785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L1871_03800	COG1794	racemase activity, acting on amino acids and derivatives
L1871_03810	COG1022	Amp-dependent synthetase and ligase
L1871_03820	COG0456	acetyltransferase
L1871_03835	COG2425	protein containing a von Willebrand factor type A (vWA) domain
L1871_03840	COG5001	Diguanylate cyclase
L1871_03840	COG5002	protein histidine kinase activity
L1871_03870	COG0456	acetyltransferase
L1871_03875	COG1902	pentaerythritol trinitrate reductase activity
L1871_03890	COG2957	Belongs to the agmatine deiminase family
L1871_03895	COG0154	amidase activity
L1871_03945	COG1136	(ABC) transporter
L1871_03960	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
L1871_03975	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
L1871_03980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
L1871_03985	COG0163	prenyltransferase activity
L1871_04000	COG1131	(ABC) transporter
L1871_04005	COG0842	Transport permease protein
L1871_04015	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
L1871_04020	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
L1871_04025	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L1871_04035	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L1871_04040	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L1871_04045	COG1489	DNA binding
L1871_04055	COG1643	Atp-dependent helicase
L1871_04060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L1871_04065	COG0346	lactoylglutathione lyase activity
L1871_04075	COG2076	Multidrug Resistance protein
L1871_04080	COG0583	DNA-binding transcription factor activity
L1871_04090	COG0671	phosphoesterase, PA-phosphatase related
L1871_04105	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
L1871_04110	COG0038	chloride channel
L1871_04120	COG0316	Belongs to the HesB IscA family
L1871_04150	COG1280	lysine exporter protein (LysE YggA)
L1871_04160	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
L1871_04175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L1871_04205	COG0745	RESPONSE REGULATOR receiver
L1871_04210	COG3104	oligopeptide transport
L1871_04215	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L1871_04220	COG1555	photosystem II stabilization
L1871_04230	COG2350	Protein conserved in bacteria
L1871_04235	COG2917	probably involved in intracellular septation
L1871_04240	COG0076	glutamate decarboxylase activity
L1871_04245	COG1272	protein, Hemolysin III
L1871_04250	COG2985	domain, Protein
L1871_04250	COG0569	domain protein
L1871_04260	COG0477	Major facilitator Superfamily
L1871_04265	COG0583	DNA-binding transcription factor activity
L1871_04270	COG3227	Zinc metalloprotease (Elastase)
L1871_04275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L1871_04280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L1871_04290	COG2731	YhcH YjgK YiaL family protein
L1871_04300	COG0668	transmembrane transport
L1871_04310	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L1871_04320	COG0789	Transcriptional regulator
L1871_04360	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
L1871_04370	COG0488	(ABC) transporter
L1871_04375	COG0516	GMP reductase activity
L1871_04375	COG0517	IMP dehydrogenase activity
L1871_04385	COG0835	chemotaxis
L1871_04385	COG0784	Response regulator, receiver
L1871_04390	COG2755	lipolytic protein G-D-S-L family
L1871_04395	COG4181	ATPase activity
L1871_04400	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
L1871_04405	COG1090	epimerase
L1871_04410	COG2200	EAL domain
L1871_04415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L1871_04420	COG2234	aminopeptidase activity
L1871_04420	COG4935	Belongs to the peptidase S8 family
L1871_04425	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L1871_04430	COG3171	Protein conserved in bacteria
L1871_04435	COG2066	Belongs to the glutaminase family
L1871_04440	COG2897	thiosulfate sulfurtransferase activity
L1871_04450	COG1132	(ABC) transporter
L1871_04475	COG0582	viral genome integration into host DNA
L1871_04505	COG3447	MASE1 domain protein
L1871_04505	COG5001	Diguanylate cyclase
L1871_04505	COG5002	protein histidine kinase activity
L1871_04510	COG4974	Belongs to the 'phage' integrase family
L1871_04540	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L1871_04555	COG0582	viral genome integration into host DNA
L1871_04575	COG4974	Belongs to the 'phage' integrase family
L1871_04610	COG3039	Transposase
L1871_04620	COG4251	negative regulation of phosphorylation
L1871_04620	COG5001	Diguanylate cyclase
L1871_04620	COG2203	Gaf domain
L1871_04620	COG3706	GGDEF domain
L1871_04630	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
L1871_04635	COG3300	MHYT domain
L1871_04635	COG5001	Diguanylate cyclase
L1871_04660	COG4628	conserved protein (DUF2132)
L1871_04665	COG0688	phosphatidylethanolamine metabolic process
L1871_04670	COG1162	GTPase activity
L1871_04675	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
L1871_04720	COG1278	Cold shock
L1871_04730	COG0840	transmembrane signaling receptor activity
L1871_04735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L1871_04785	COG0848	biopolymer transport protein
L1871_04790	COG0811	peptide transport
L1871_04795	COG0811	peptide transport
L1871_04805	COG4206	TonB-dependent receptor
L1871_04810	COG4174	ABC transporter (Permease)
L1871_04815	COG4239	(ABC) transporter, permease
L1871_04825	COG0444	Belongs to the ABC transporter superfamily
L1871_04830	COG4608	Belongs to the ABC transporter superfamily
L1871_04835	COG2195	Cleaves the N-terminal amino acid of tripeptides
L1871_04840	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
L1871_04845	COG1073	alpha beta
L1871_04860	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
L1871_04885	COG0243	molybdopterin cofactor binding
L1871_04890	COG1648	precorrin-2 dehydrogenase activity
L1871_04890	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L1871_04900	COG1116	anion transmembrane transporter activity
L1871_04900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L1871_04905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L1871_04910	COG1116	anion transmembrane transporter activity
L1871_04915	COG2146	nitrite reductase [NAD(P)H] activity
L1871_04915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L1871_04920	COG2146	nitrite reductase [NAD(P)H] activity
L1871_04920	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L1871_04925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L1871_04930	COG2313	pseudouridylate synthase activity
L1871_04950	COG0521	Mo-molybdopterin cofactor biosynthetic process
L1871_04960	COG2966	Psort location CytoplasmicMembrane, score
L1871_04965	COG3610	response to peptide
L1871_04975	COG4175	Glycine betaine
L1871_04980	COG4176	ABC-type proline glycine betaine transport system permease component
L1871_04985	COG2113	Glycine betaine
L1871_04990	COG0175	sulfate reduction
L1871_04995	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L1871_05000	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L1871_05005	COG0384	phenazine biosynthesis protein PhzF
L1871_05010	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
L1871_05025	COG0786	glutamate:sodium symporter activity
L1871_05030	COG0252	asparaginase activity
L1871_05040	COG2425	protein containing a von Willebrand factor type A (vWA) domain
L1871_05045	COG3139	Protein of unknown function (DUF1315)
L1871_05065	COG0616	signal peptide processing
L1871_05070	COG0446	pyridine nucleotide-disulphide oxidoreductase
L1871_05070	COG1902	pentaerythritol trinitrate reductase activity
L1871_05075	COG0778	Nitroreductase
L1871_05090	COG0110	maltose O-acetyltransferase activity
L1871_05095	COG2264	protein methyltransferase activity
L1871_05100	COG0604	alcohol dehydrogenase
L1871_05105	COG0583	DNA-binding transcription factor activity
L1871_05110	COG1263	PTS System
L1871_05110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L1871_05110	COG2190	(PTS) system
L1871_05115	COG4145	pantothenate transmembrane transporter activity
L1871_05120	COG3924	membrane
L1871_05125	COG0439	Biotin carboxylase
L1871_05130	COG0511	ligase activity, forming carbon-carbon bonds
L1871_05135	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
L1871_05140	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L1871_05155	COG3381	protein complex oligomerization
L1871_05165	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
L1871_05175	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
L1871_05180	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L1871_05180	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L1871_05195	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
L1871_05200	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
L1871_05205	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
L1871_05210	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L1871_05215	COG4172	Belongs to the ABC transporter superfamily
L1871_05225	COG0601	transmembrane transport
L1871_05230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L1871_05235	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
L1871_05240	COG0142	geranyltranstransferase activity
L1871_05245	COG1722	exodeoxyribonuclease VII activity
L1871_05250	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
L1871_05255	COG1360	Flagellar Motor Protein
L1871_05270	COG1534	Rna-binding protein
L1871_05275	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
L1871_05285	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L1871_05290	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L1871_05295	COG0149	triose-phosphate isomerase activity
L1871_05300	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
L1871_05315	COG0779	Required for maturation of 30S ribosomal subunits
L1871_05320	COG0195	Participates in both transcription termination and antitermination
L1871_05325	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
L1871_05330	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
L1871_05335	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L1871_05340	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
L1871_05345	COG1185	polyribonucleotide nucleotidyltransferase activity
L1871_05350	COG2211	Major facilitator Superfamily
L1871_05355	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
L1871_05360	COG1422	Protein of unknown function (DUF1090)
L1871_05365	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L1871_05370	COG0826	peptidase U32
L1871_05385	COG0312	modulator of DNA gyrase
L1871_05390	COG0312	modulator of DNA gyrase
L1871_05400	COG4974	Belongs to the 'phage' integrase family
L1871_05405	COG1970	mechanosensitive ion channel activity
L1871_05420	COG0789	Transcriptional regulator
L1871_05435	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
L1871_05445	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L1871_05450	COG0321	lipoyl(octanoyl) transferase activity
L1871_05455	COG2921	Belongs to the UPF0250 family
L1871_05460	COG1686	Belongs to the peptidase S11 family
L1871_05465	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
L1871_05470	COG2951	lytic endotransglycosylase activity
L1871_05475	COG0772	Belongs to the SEDS family
L1871_05480	COG0768	penicillin binding
L1871_05485	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
L1871_05490	COG0799	negative regulation of ribosome biogenesis
L1871_05495	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
L1871_05510	COG0495	leucyl-tRNA aminoacylation
L1871_05515	COG2888	peptidyl-tyrosine sulfation
L1871_05520	COG0815	Transfers the fatty acyl group on membrane lipoproteins
L1871_05525	COG4535	Mg2 and Co2 transporter CorC
L1871_05530	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
L1871_05535	COG1702	phosphate starvation-inducible protein PhoH
L1871_05540	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
L1871_05545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L1871_05550	COG1335	isochorismatase
L1871_05565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L1871_05580	COG2199	diguanylate cyclase activity
L1871_05590	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
L1871_05610	COG1464	Belongs to the NlpA lipoprotein family
L1871_05620	COG2011	ABC-type metal ion transport system permease component
L1871_05625	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
L1871_05635	COG0516	GMP reductase activity
L1871_05640	COG4067	protein conserved in archaea
L1871_05640	COG0189	ligase activity
L1871_05660	COG0300	oxidoreductase activity
L1871_05680	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L1871_05685	COG3214	Protein conserved in bacteria
L1871_05705	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
L1871_05710	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
L1871_05715	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L1871_05720	COG1053	succinate dehydrogenase
L1871_05730	COG0584	glycerophosphoryl diester phosphodiesterase
L1871_05735	COG1511	domain protein
L1871_05735	COG3264	Mechanosensitive ion channel
L1871_05745	COG0739	heme binding
L1871_05760	COG0583	DNA-binding transcription factor activity
L1871_05775	COG0583	DNA-binding transcription factor activity
L1871_05780	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
L1871_05810	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
L1871_05815	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
L1871_05825	COG0338	D12 class N6 adenine-specific DNA methyltransferase
L1871_05830	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L1871_05835	COG0546	phosphoglycolate phosphatase activity
L1871_05840	COG0180	Tryptophanyl-tRNA synthetase
L1871_05855	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L1871_05865	COG1012	belongs to the aldehyde dehydrogenase family
L1871_05880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L1871_05895	COG0657	acetylesterase activity
L1871_05905	COG0471	metal ion transport
L1871_05905	COG0490	domain, Protein
L1871_05950	COG0012	GTP binding
L1871_05955	COG0193	aminoacyl-tRNA hydrolase activity
L1871_05960	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L1871_05970	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
L1871_05975	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
L1871_05980	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
L1871_05985	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
L1871_05990	COG2890	protein-(glutamine-N5) methyltransferase activity
L1871_06000	COG2912	Transglutaminase-like superfamily
L1871_06005	COG2877	3-deoxy-8-phosphooctulonate synthase activity
L1871_06015	COG1301	dicarboxylic acid transport
L1871_06025	COG3039	Transposase
L1871_06030	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
L1871_06045	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L1871_06050	COG1115	amino acid carrier protein
L1871_06070	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
L1871_06080	COG0189	ligase activity
L1871_06085	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L1871_06095	COG3091	SprT-like family
L1871_06105	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L1871_06110	COG3039	Transposase
L1871_06140	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
L1871_06145	COG0739	heme binding
L1871_06150	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L1871_06155	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
L1871_06155	COG3408	Glycogen debranching enzyme
L1871_06165	COG1881	PFAM PEBP family protein
L1871_06170	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
L1871_06175	COG0583	DNA-binding transcription factor activity
L1871_06185	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
L1871_06195	COG0583	DNA-binding transcription factor activity
L1871_06200	COG1028	Short-chain dehydrogenase reductase Sdr
L1871_06205	COG0616	signal peptide processing
L1871_06210	COG3724	N-succinylarginine dihydrolase activity
L1871_06230	COG0840	transmembrane signaling receptor activity
L1871_06240	COG2971	BadF BadG BcrA BcrD
L1871_06250	COG4608	Belongs to the ABC transporter superfamily
L1871_06255	COG0444	Belongs to the ABC transporter superfamily
L1871_06260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L1871_06275	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
L1871_06290	COG1484	DNA-dependent DNA replication
L1871_06305	COG3039	Transposase
L1871_06310	COG3039	Transposase
L1871_06335	COG0640	Transcriptional regulator
L1871_06340	COG0798	PFAM Bile acid sodium symporter
L1871_06345	COG1393	Belongs to the ArsC family
L1871_06355	COG1677	Flagellar hook-basal body complex protein FliE
L1871_06365	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L1871_06420	COG1684	flagellar biosynthetic protein fliR
L1871_06430	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
L1871_06455	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
L1871_06460	COG0643	Histidine kinase
L1871_06460	COG0784	Response regulator, receiver
L1871_06460	COG2198	Histidine kinase
L1871_06465	COG2201	protein-glutamate methylesterase activity
L1871_06470	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
L1871_06475	COG1360	Flagellar Motor Protein
L1871_06480	COG1192	Involved in chromosome partitioning
L1871_06490	COG0835	chemotaxis
L1871_06505	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
L1871_06510	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
L1871_06515	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
L1871_06520	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
L1871_06525	COG1138	Cytochrome C-type biogenesis protein
L1871_06530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L1871_06540	COG0457	Tetratricopeptide repeat
L1871_06555	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
L1871_06560	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
L1871_06560	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
L1871_06575	COG0259	pyridoxamine-phosphate oxidase activity
L1871_06605	COG3153	acetyltransferase
L1871_06620	COG0800	Aldolase
L1871_06640	COG2801	Transposase and inactivated derivatives
L1871_06645	COG0582	viral genome integration into host DNA
L1871_06655	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
L1871_06660	COG2867	negative regulation of translational initiation
L1871_06665	COG2914	Belongs to the UPF0125 (RnfH) family
L1871_06670	COG0702	epimerase
L1871_06675	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L1871_06680	COG1454	alcohol dehydrogenase
L1871_06690	COG0564	pseudouridine synthase activity
L1871_06695	COG1957	nucleoside hydrolase
L1871_06720	COG1280	lysine exporter protein (LysE YggA)
L1871_06730	COG3263	regulation of cellular component size
L1871_06740	COG1876	peptidase activity
L1871_06745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L1871_06750	COG1393	Belongs to the ArsC family
L1871_06765	COG1473	amidohydrolase
L1871_06780	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
L1871_06785	COG0017	Asparaginyl-tRNA synthetase
L1871_06805	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
L1871_06810	COG0156	8-amino-7-oxononanoate synthase activity
L1871_06815	COG1073	alpha beta
L1871_06815	COG2226	methyltransferase
L1871_06820	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
L1871_06825	COG0501	Belongs to the peptidase M48B family
L1871_06830	COG3217	Mosc domain protein beta barrel domain protein
L1871_06830	COG3217	Mosc domain protein beta barrel domain protein
L1871_06830	COG0633	Ferredoxin
L1871_06830	COG0633	Ferredoxin
L1871_06840	COG0674	pyruvate-flavodoxin oxidoreductase activity
L1871_06840	COG1013	pyruvate-flavodoxin oxidoreductase activity
L1871_06840	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
L1871_06840	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
L1871_06845	COG2841	Protein conserved in bacteria
L1871_06855	COG0534	Mate efflux family protein
L1871_06880	COG1454	alcohol dehydrogenase
L1871_06890	COG1309	transcriptional regulator
L1871_06905	COG0791	NLP P60 protein
L1871_06910	COG0583	DNA-binding transcription factor activity
L1871_06930	COG0500	methyltransferase
L1871_06935	COG4106	trans-aconitate 2-methyltransferase activity
L1871_06940	COG1801	Protein of unknown function DUF72
L1871_06945	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
L1871_06950	COG0217	transcriptional regulatory protein
L1871_06955	COG2194	sulfuric ester hydrolase activity
L1871_06960	COG1846	Transcriptional regulator
L1871_06960	COG1940	carbohydrate kinase activity
L1871_06965	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
L1871_06970	COG0363	glucosamine-6-phosphate deaminase activity
L1871_06975	COG2190	(PTS) system
L1871_06975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L1871_06975	COG1263	PTS System
L1871_06985	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L1871_06990	COG0735	belongs to the Fur family
L1871_07000	COG0716	FMN binding
L1871_07015	COG0596	Alpha beta hydrolase
L1871_07020	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
L1871_07025	COG0033	Phosphoglucomutase
L1871_07035	COG1846	Transcriptional regulator
L1871_07040	COG2951	lytic endotransglycosylase activity
L1871_07045	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L1871_07050	COG4136	ATPase activity
L1871_07060	COG4134	Bacterial extracellular solute-binding protein
L1871_07065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L1871_07070	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L1871_07080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L1871_07090	COG0729	surface antigen
L1871_07095	COG2911	Protein conserved in bacteria
L1871_07115	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
L1871_07125	COG0741	lytic transglycosylase activity
L1871_07140	COG1607	acyl-coa hydrolase
L1871_07155	COG0741	lytic transglycosylase activity
L1871_07155	COG1388	LysM domain
L1871_07165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L1871_07170	COG2226	methyltransferase
L1871_07175	COG0328	RNA-DNA hybrid ribonuclease activity
L1871_07180	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L1871_07190	COG0784	Response regulator, receiver
L1871_07190	COG3437	response regulator, receiver
L1871_07195	COG1960	acyl-CoA dehydrogenase activity
L1871_07200	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
L1871_07205	COG0121	glutamine amidotransferase
L1871_07215	COG0391	Required for morphogenesis under gluconeogenic growth conditions
L1871_07240	COG2197	response regulator
L1871_07245	COG3850	Histidine kinase
L1871_07250	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L1871_07255	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L1871_07255	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
L1871_07265	COG0243	molybdopterin cofactor binding
L1871_07270	COG0437	4 iron, 4 sulfur cluster binding
L1871_07275	COG0348	domain, Protein
L1871_07285	COG3005	denitrification pathway
L1871_07290	COG0521	Mo-molybdopterin cofactor biosynthetic process
L1871_07295	COG0315	cyclic pyranopterin monophosphate synthase activity
L1871_07300	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
L1871_07305	COG0314	molybdopterin synthase activity
L1871_07320	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
L1871_07325	COG2267	carboxylic ester hydrolase activity
L1871_07340	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
L1871_07350	COG0302	gtp cyclohydrolase
L1871_07355	COG0840	transmembrane signaling receptor activity
L1871_07360	COG0840	transmembrane signaling receptor activity
L1871_07365	COG2759	Belongs to the formate--tetrahydrofolate ligase family
L1871_07375	COG0583	DNA-binding transcription factor activity
L1871_07390	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
L1871_07405	COG2195	Cleaves the N-terminal amino acid of tripeptides
L1871_07410	COG1166	arginine decarboxylase activity
L1871_07435	COG1061	Type III restriction enzyme res subunit
L1871_07470	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L1871_07475	COG1187	pseudouridine synthase activity
L1871_07480	COG2807	transmembrane transport
L1871_07490	COG0583	DNA-binding transcription factor activity
L1871_07510	COG2979	Protein of unknown function (DUF533)
L1871_07520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L1871_07525	COG1271	oxidase subunit
L1871_07530	COG1294	oxidase, subunit
L1871_07540	COG2814	Major facilitator Superfamily
L1871_07545	COG0656	L-ascorbic acid biosynthetic process
L1871_07565	COG0583	DNA-binding transcription factor activity
L1871_07570	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
L1871_07575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
L1871_07585	COG1349	DNA-binding transcription factor activity
L1871_07595	COG0584	glycerophosphoryl diester phosphodiesterase
L1871_07600	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L1871_07605	COG0287	Prephenate dehydrogenase
L1871_07605	COG1605	Chorismate mutase
L1871_07615	COG3085	chromosome segregation
L1871_07620	COG4574	serine-type endopeptidase inhibitor activity
L1871_07640	COG1770	oligopeptidase
L1871_07645	COG4771	TonB-dependent receptor
L1871_07650	COG3083	sulfuric ester hydrolase activity
L1871_07655	COG3082	Protein of unknown function (DUF1414)
L1871_07660	COG3081	Nucleoid-associated protein
L1871_07670	COG1175	transmembrane transport
L1871_07675	COG3833	ABC-type maltose transport systems, permease component
L1871_07680	COG3842	ATPase activity
L1871_07690	COG0596	Alpha beta hydrolase
L1871_07705	COG0425	Belongs to the sulfur carrier protein TusA family
L1871_07710	COG4783	chaperone-mediated protein folding
L1871_07720	COG1393	Belongs to the ArsC family
L1871_07745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L1871_07750	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
L1871_07755	COG2431	L-lysine efflux transmembrane transporter activity
L1871_07765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L1871_07775	COG4160	amino acid transport
L1871_07785	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
L1871_07795	COG0446	pyridine nucleotide-disulphide oxidoreductase
L1871_07820	COG0628	permease
L1871_07825	COG2373	Large extracellular alpha-helical protein
L1871_07830	COG4953	penicillin-binding protein 1C
L1871_07840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L1871_07840	COG0301	tRNA thio-modification
L1871_07855	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
L1871_07860	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
L1871_07905	COG2089	acid synthase
L1871_07920	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
L1871_07925	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
L1871_07935	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
L1871_07940	COG1086	Polysaccharide biosynthesis protein
L1871_07945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L1871_07955	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L1871_07975	COG0346	lactoylglutathione lyase activity
L1871_07980	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L1871_07985	COG4660	Part of a membrane complex involved in electron transport
L1871_07990	COG4659	FMN binding
L1871_07995	COG4658	electron transport chain
L1871_08005	COG2878	Part of a membrane complex involved in electron transport
L1871_08010	COG4657	Part of a membrane complex involved in electron transport
L1871_08040	COG2932	Transcriptional regulator
L1871_08150	COG0640	Transcriptional regulator
L1871_08160	COG4373	Mu-like prophage FluMu protein gp28
L1871_08165	COG4383	Mu-like prophage protein gp29
L1871_08190	COG4388	Caudovirus prohead serine protease
L1871_08195	COG4397	Mu-like prophage major head subunit gpT
L1871_08270	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
L1871_08275	COG1288	antiporter activity
L1871_08280	COG0436	Aminotransferase
L1871_08290	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L1871_08295	COG2027	D-alanyl-D-alanine carboxypeptidase
L1871_08300	COG1061	Type III restriction enzyme res subunit
L1871_08305	COG1566	PFAM secretion protein HlyD family protein
L1871_08315	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
L1871_08315	COG3264	Mechanosensitive ion channel
L1871_08320	COG1966	Carbon starvation protein
L1871_08325	COG3279	Response regulator of the LytR AlgR family
L1871_08330	COG3275	phosphorelay sensor kinase activity
L1871_08340	COG1454	alcohol dehydrogenase
L1871_08340	COG1012	belongs to the aldehyde dehydrogenase family
L1871_08350	COG2095	MarC family integral membrane protein
L1871_08360	COG0601	transmembrane transport
L1871_08365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L1871_08370	COG0444	Belongs to the ABC transporter superfamily
L1871_08385	COG0861	Integral membrane protein TerC family
L1871_08390	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L1871_08400	COG1301	dicarboxylic acid transport
L1871_08420	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
L1871_08435	COG0537	adenosine 5'-monophosphoramidase activity
L1871_08470	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L1871_08475	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L1871_08490	COG2354	Protein conserved in bacteria
L1871_08495	COG1164	Oligoendopeptidase f
L1871_08500	COG1164	Oligoendopeptidase f
L1871_08505	COG3150	esterase
L1871_08510	COG1252	NADH dehydrogenase
L1871_08515	COG0393	Putative heavy-metal-binding
L1871_08520	COG1619	proteins homologs of microcin C7 resistance protein MccF
L1871_08525	COG1368	sulfuric ester hydrolase activity
L1871_08535	COG0527	aspartate kinase activity
L1871_08540	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
L1871_08540	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
L1871_08545	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L1871_08570	COG0583	DNA-binding transcription factor activity
L1871_08575	COG1620	l-lactate permease
L1871_08580	COG0247	lactate metabolic process
L1871_08585	COG1139	Iron-sulfur cluster binding protein
L1871_08615	COG0577	efflux transmembrane transporter activity
L1871_08620	COG1136	(ABC) transporter
L1871_08640	COG2814	Major facilitator Superfamily
L1871_08665	COG0672	)-iron permease
L1871_08700	COG2308	Evidence 4 Homologs of previously reported genes of
L1871_08715	COG0659	secondary active sulfate transmembrane transporter activity
L1871_08740	COG3501	Rhs element vgr protein
L1871_08750	COG3209	COG3209 Rhs family protein
L1871_08810	COG3829	transcription factor binding
L1871_08855	COG3039	Transposase
L1871_08875	COG0437	4 iron, 4 sulfur cluster binding
L1871_08880	COG5557	Pfam Polysulphide reductase, NrfD
L1871_08885	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
L1871_08890	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
L1871_08895	COG1773	rubredoxin
L1871_08905	COG0601	transmembrane transport
L1871_08910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L1871_08915	COG0444	Belongs to the ABC transporter superfamily
L1871_08920	COG3842	ATPase activity
L1871_08925	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
L1871_08950	COG0309	Hydrogenase expression formation protein (HypE)
L1871_08960	COG0298	carbon dioxide binding
L1871_08965	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
L1871_08970	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
L1871_08975	COG0326	Molecular chaperone. Has ATPase activity
L1871_08980	COG0563	adenylate kinase activity
L1871_08985	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
L1871_08990	COG3788	relative of glutathione S-transferase, MAPEG superfamily
L1871_08995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L1871_09000	COG0840	transmembrane signaling receptor activity
L1871_09015	COG3300	MHYT domain
L1871_09015	COG5001	Diguanylate cyclase
L1871_09040	COG1021	2,3-dihydroxybenzoate-AMP ligase
L1871_09045	COG3433	isochorismatase activity
L1871_09045	COG1535	isochorismatase
L1871_09050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L1871_09055	COG1028	Short-chain dehydrogenase reductase Sdr
L1871_09065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L1871_09080	COG1120	ATPase activity
L1871_09085	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L1871_09090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L1871_09095	COG4771	TonB-dependent receptor
L1871_09135	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
L1871_09140	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
L1871_09145	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L1871_09150	COG0861	Integral membrane protein TerC family
L1871_09165	COG1022	Amp-dependent synthetase and ligase
L1871_09170	COG0295	cytidine deaminase activity
L1871_09175	COG1346	cytolysis
L1871_09180	COG1380	Effector of murein hydrolase LrgA
L1871_09185	COG3345	alpha-galactosidase
L1871_09195	COG2925	Exonuclease
L1871_09205	COG3039	Transposase
L1871_09225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L1871_09230	COG0444	Belongs to the ABC transporter superfamily
L1871_09235	COG2814	Major facilitator Superfamily
L1871_09255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L1871_09260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L1871_09265	COG0404	The glycine cleavage system catalyzes the degradation of glycine
L1871_09270	COG0509	glycine decarboxylation via glycine cleavage system
L1871_09275	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
L1871_09275	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
L1871_09295	COG0477	Major facilitator Superfamily
L1871_09300	COG3634	alkyl hydroperoxide reductase activity
L1871_09305	COG0450	alkyl hydroperoxide reductase
L1871_09310	COG0517	IMP dehydrogenase activity
L1871_09315	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
L1871_09320	COG0343	queuine tRNA-ribosyltransferase activity
L1871_09325	COG1862	Preprotein translocase
L1871_09330	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L1871_09335	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L1871_09340	COG2897	thiosulfate sulfurtransferase activity
L1871_09350	COG0826	peptidase U32
L1871_09355	COG0826	peptidase U32
L1871_09360	COG3154	lipid carrier protein
L1871_09375	COG1104	cysteine desulfurase activity
L1871_09380	COG0822	iron-sulfur transferase activity
L1871_09390	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
L1871_09395	COG0443	Heat shock 70 kDa protein
L1871_09400	COG0633	Ferredoxin
L1871_09410	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
L1871_09415	COG0105	UTP biosynthetic process
L1871_09420	COG0820	rRNA (adenine-C2-)-methyltransferase activity
L1871_09430	COG1426	Protein conserved in bacteria
L1871_09440	COG0124	histidyl-tRNA synthetase
L1871_09445	COG2976	Protein conserved in bacteria
L1871_09450	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L1871_09455	COG1160	GTP binding
L1871_09460	COG1645	bacterial-type flagellum-dependent swarming motility
L1871_09465	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
L1871_09470	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L1871_09470	COG0047	phosphoribosylformylglycinamidine synthase activity
L1871_09475	COG1007	ATP synthesis coupled electron transport
L1871_09480	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L1871_09490	COG0713	ATP synthesis coupled electron transport
L1871_09495	COG0839	Belongs to the complex I subunit 6 family
L1871_09500	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L1871_09505	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
L1871_09510	COG1034	ATP synthesis coupled electron transport
L1871_09525	COG0649	NAD binding
L1871_09525	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L1871_09530	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L1871_09535	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L1871_09540	COG1360	Flagellar Motor Protein
L1871_09545	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
L1871_09565	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
L1871_09585	COG0724	RNA recognition motif
L1871_09590	COG4989	oxidoreductase activity
L1871_09615	COG0745	RESPONSE REGULATOR receiver
L1871_09620	COG0583	DNA-binding transcription factor activity
L1871_09630	COG5001	Diguanylate cyclase
L1871_09630	COG3300	MHYT domain
L1871_09635	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
L1871_09670	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L1871_09675	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
L1871_09680	COG0539	negative regulation of cytoplasmic translation
L1871_09685	COG0776	regulation of translation
L1871_09695	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
L1871_09715	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
L1871_09720	COG0602	queuosine metabolic process
L1871_09725	COG3530	Putative quorum-sensing-regulated virulence factor
L1871_09730	COG2096	Adenosyltransferase
L1871_09735	COG2916	Histone family protein nucleoid-structuring protein H-NS
L1871_09740	COG1757	Na H antiporter
L1871_09745	COG1435	thymidine kinase activity
L1871_09765	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
L1871_09780	COG1349	DNA-binding transcription factor activity
L1871_09790	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
L1871_09800	COG3550	peptidyl-serine autophosphorylation
L1871_09850	COG3039	Transposase
L1871_09855	COG2226	methyltransferase
L1871_09885	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
L1871_09900	COG2910	NAD(P)H-binding
L1871_09905	COG0583	DNA-binding transcription factor activity
L1871_09910	COG4977	sequence-specific DNA binding
L1871_09910	COG1917	Cupin 2, conserved barrel domain protein
L1871_09915	COG2200	EAL domain
L1871_09920	COG3706	GGDEF domain
L1871_09930	COG4774	siderophore transport
L1871_09940	COG0583	DNA-binding transcription factor activity
L1871_09945	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
L1871_09955	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
L1871_09955	COG0617	tRNA 3'-terminal CCA addition
L1871_09955	COG0517	IMP dehydrogenase activity
L1871_09960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L1871_09965	COG3046	protein related to deoxyribodipyrimidine photolyase
L1871_09980	COG3088	subunit of a heme lyase
L1871_09980	COG4235	cytochrome complex assembly
L1871_09985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L1871_10005	COG3301	Polysulphide reductase, NrfD
L1871_10010	COG0437	4 iron, 4 sulfur cluster binding
L1871_10015	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
L1871_10035	COG0247	lactate metabolic process
L1871_10045	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
L1871_10050	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
L1871_10055	COG3012	SEC-C Motif Domain Protein
L1871_10060	COG0840	transmembrane signaling receptor activity
L1871_10065	COG1940	carbohydrate kinase activity
L1871_10065	COG1846	Transcriptional regulator
L1871_10070	COG3290	protein histidine kinase activity
L1871_10075	COG4565	transcriptional regulatory protein
L1871_10095	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
L1871_10100	COG0569	domain protein
L1871_10100	COG2985	domain, Protein
L1871_10110	COG0556	nucleotide-excision repair
L1871_10120	COG0586	Pfam SNARE associated Golgi protein
L1871_10125	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
L1871_10130	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L1871_10135	COG2186	Transcriptional regulator
L1871_10140	COG2719	SpoVR family
L1871_10145	COG2718	Belongs to the UPF0229 family
L1871_10150	COG2766	serine protein kinase
L1871_10155	COG0514	ATP-dependent DNA helicase (RecQ)
L1871_10160	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
L1871_10165	COG0814	amino acid
L1871_10195	COG0058	SHG alpha-glucan phosphorylase activity
L1871_10210	COG0471	metal ion transport
L1871_10215	COG3118	belongs to the thioredoxin family
L1871_10225	COG1132	(ABC) transporter
L1871_10230	COG1132	(ABC) transporter
L1871_10245	COG2501	S4 domain
L1871_10255	COG3243	poly(R)-hydroxyalkanoic acid synthase
L1871_10275	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
L1871_10280	COG2329	Antibiotic biosynthesis monooxygenase
L1871_10305	COG3039	Transposase
L1871_10315	COG0513	Belongs to the DEAD box helicase family
L1871_10320	COG0386	Belongs to the glutathione peroxidase family
L1871_10330	COG1181	Belongs to the D-alanine--D-alanine ligase family
L1871_10335	COG3148	PFAM DTW domain containing protein
L1871_10340	COG0730	response to heat
L1871_10345	COG0583	DNA-binding transcription factor activity
L1871_10360	COG3593	DNA synthesis involved in DNA repair
L1871_10400	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
L1871_10405	COG1011	Hydrolase
L1871_10410	COG1473	amidohydrolase
L1871_10420	COG0205	6-phosphofructokinase activity
L1871_10430	COG1434	Gram-negative-bacterium-type cell wall biogenesis
L1871_10435	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L1871_10445	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
L1871_10450	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
L1871_10485	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
L1871_10490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L1871_10525	COG1280	lysine exporter protein (LysE YggA)
L1871_10535	COG2824	Alkylphosphonate utilization operon protein PhnA
L1871_10570	COG2840	Smr protein MutS2
L1871_10575	COG2890	protein-(glutamine-N5) methyltransferase activity
L1871_10580	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
L1871_10590	COG0513	Belongs to the DEAD box helicase family
L1871_10595	COG5654	RES domain protein
L1871_10605	COG0814	amino acid
L1871_10610	COG1609	Transcriptional regulator
L1871_10615	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L1871_10615	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
L1871_10620	COG1105	Belongs to the carbohydrate kinase PfkB family
L1871_10625	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L1871_10625	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L1871_10625	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
L1871_10635	COG3313	Fe-S protein
L1871_10640	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
L1871_10645	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L1871_10650	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L1871_10655	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L1871_10665	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L1871_10695	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
L1871_10700	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
L1871_10705	COG0291	Belongs to the bacterial ribosomal protein bL35 family
L1871_10710	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
L1871_10715	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
L1871_10720	COG0072	phenylalanine-tRNA ligase activity
L1871_10720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L1871_10725	COG0776	regulation of translation
L1871_10760	COG0675	Transposase, IS605 OrfB family
L1871_10770	COG1609	Transcriptional regulator
L1871_10775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L1871_10780	COG1879	ABC-type sugar transport system periplasmic component
L1871_10785	COG1172	Belongs to the binding-protein-dependent transport system permease family
L1871_10790	COG1129	ABC transporter
L1871_10795	COG1869	D-ribose catabolic process
L1871_10810	COG0675	Transposase, IS605 OrfB family
L1871_10825	COG0037	tRNA processing
L1871_10830	COG0589	response to stress
L1871_10835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L1871_10850	COG2217	Heavy metal translocating P-type atpase
L1871_10860	COG2010	Cytochrome c
L1871_10875	COG3278	Belongs to the heme-copper respiratory oxidase family
L1871_10885	COG1956	GAF domain-containing protein
L1871_10890	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
L1871_10900	COG0308	aminopeptidase N
L1871_10910	COG2902	Dehydrogenase
L1871_10915	COG0167	dihydroorotate dehydrogenase activity
L1871_10925	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
L1871_10925	COG0116	Belongs to the methyltransferase superfamily
L1871_10935	COG0488	(ABC) transporter
L1871_10985	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L1871_10995	COG0789	Transcriptional regulator
L1871_11030	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L1871_11065	COG2826	transposase and inactivated derivatives, IS30 family
L1871_11080	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L1871_11085	COG0625	glutathione transferase activity
L1871_11115	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
L1871_11125	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L1871_11145	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L1871_11175	COG3039	Transposase
L1871_11230	COG1695	Transcriptional regulator
L1871_11255	COG3173	Aminoglycoside phosphotransferase
L1871_11270	COG1660	Displays ATPase and GTPase activities
L1871_11410	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
L1871_11415	COG1067	ATP-dependent peptidase activity
L1871_11425	COG3141	response to X-ray
L1871_11435	COG2995	paraquat-inducible protein a
L1871_11440	COG3008	intermembrane lipid transfer
L1871_11445	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
L1871_11445	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
L1871_11460	COG0084	hydrolase, TatD family'
L1871_11465	COG0470	DNA polymerase III
L1871_11470	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
L1871_11475	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L1871_11480	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L1871_11485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L1871_11490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L1871_11495	COG1028	Short-chain dehydrogenase reductase Sdr
L1871_11505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L1871_11510	COG0416	fatty acid biosynthetic process
L1871_11515	COG0333	Belongs to the bacterial ribosomal protein bL32 family
L1871_11520	COG1399	metal-binding, possibly nucleic acid-binding protein
L1871_11535	COG0564	pseudouridine synthase activity
L1871_11540	COG1530	ribonuclease E activity
L1871_11545	COG0306	phosphate transporter
L1871_11550	COG0717	Belongs to the dCTP deaminase family
L1871_11555	COG0572	uridine kinase
L1871_11560	COG0489	protein tyrosine kinase activity
L1871_11565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L1871_11565	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L1871_11575	COG1254	Belongs to the acylphosphatase family
L1871_11580	COG0840	transmembrane signaling receptor activity
L1871_11585	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
L1871_11600	COG0709	Synthesizes selenophosphate from selenide and ATP
L1871_11605	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
L1871_11610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L1871_11615	COG3437	response regulator, receiver
L1871_11625	COG0784	Response regulator, receiver
L1871_11625	COG2205	protein histidine kinase activity
L1871_11625	COG5002	protein histidine kinase activity
L1871_11630	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
L1871_11640	COG1643	Atp-dependent helicase
L1871_11645	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
L1871_11645	COG0617	tRNA 3'-terminal CCA addition
L1871_11645	COG0517	IMP dehydrogenase activity
L1871_11650	COG2197	response regulator
L1871_11655	COG3314	Sporulation integral membrane protein YlbJ
L1871_11800	COG0583	DNA-binding transcription factor activity
L1871_11805	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
L1871_11815	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
L1871_11820	COG2832	Protein of unknown function (DUF454)
L1871_11825	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L1871_11835	COG0697	spore germination
L1871_11850	COG0318	PFAM AMP-dependent synthetase and ligase
L1871_11855	COG0596	Alpha beta hydrolase
L1871_11865	COG1214	PFAM Peptidase M22, glycoprotease
L1871_11870	COG1199	ATP-dependent helicase activity
L1871_11880	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
L1871_11885	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
L1871_11890	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
L1871_11895	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
L1871_11895	COG0131	Imidazoleglycerol-phosphate dehydratase
L1871_11900	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
L1871_11905	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
L1871_11910	COG3437	response regulator, receiver
L1871_11920	COG2198	Histidine kinase
L1871_11920	COG0784	Response regulator, receiver
L1871_11920	COG2205	protein histidine kinase activity
L1871_11925	COG0107	imidazoleglycerol-phosphate synthase activity
L1871_11930	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
L1871_11930	COG0140	phosphoribosyl-ATP diphosphatase activity
L1871_11940	COG2378	regulation of single-species biofilm formation
L1871_11950	COG3134	Outer membrane lipoprotein
L1871_11965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L1871_11995	COG4681	YaeQ
L1871_12005	COG1250	3-hydroxyacyl-CoA dehydrogenase
L1871_12005	COG1024	Enoyl-CoA hydratase
L1871_12010	COG0183	Belongs to the thiolase family
L1871_12015	COG0714	Associated with various cellular activities
L1871_12045	COG1595	DNA-templated transcription, initiation
L1871_12055	COG2067	long-chain fatty acid transport protein
L1871_12060	COG2067	long-chain fatty acid transport protein
L1871_12065	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
L1871_12080	COG1301	dicarboxylic acid transport
L1871_12085	COG3123	guanosine phosphorylase activity
L1871_12090	COG1760	l-serine dehydratase
L1871_12095	COG1760	l-serine dehydratase
L1871_12100	COG2951	lytic endotransglycosylase activity
L1871_12105	COG3100	YcgL domain-containing protein
L1871_12110	COG0850	regulation of cytokinetic process
L1871_12115	COG2894	cell division
L1871_12120	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
L1871_12125	COG3099	Belongs to the UPF0263 family
L1871_12130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L1871_12145	COG2996	Protein conserved in bacteria
L1871_12170	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L1871_12175	COG0697	spore germination
L1871_12180	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
L1871_12185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L1871_12200	COG0307	riboflavin synthase, alpha
L1871_12210	COG0534	Mate efflux family protein
L1871_12240	COG0417	DNA replication proofreading
L1871_12255	COG1560	Kdo2-lipid A biosynthetic process
L1871_12260	COG1560	Kdo2-lipid A biosynthetic process
L1871_12270	COG0583	DNA-binding transcription factor activity
L1871_12275	COG0673	inositol 2-dehydrogenase activity
L1871_12280	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
L1871_12300	COG0583	DNA-binding transcription factor activity
L1871_12310	COG2723	6-phospho-beta-galactosidase activity
L1871_12315	COG0583	DNA-binding transcription factor activity
L1871_12325	COG0243	molybdopterin cofactor binding
L1871_12330	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L1871_12345	COG0583	DNA-binding transcription factor activity
L1871_12350	COG1879	ABC-type sugar transport system periplasmic component
L1871_12355	COG1129	ABC transporter
L1871_12360	COG1172	Belongs to the binding-protein-dependent transport system permease family
L1871_12365	COG1172	Belongs to the binding-protein-dependent transport system permease family
L1871_12380	COG0730	response to heat
L1871_12390	COG1028	Short-chain dehydrogenase reductase Sdr
L1871_12400	COG1024	Enoyl-CoA hydratase
L1871_12405	COG1024	Enoyl-CoA hydratase
L1871_12410	COG1960	acyl-CoA dehydrogenase activity
L1871_12420	COG1960	acyl-CoA dehydrogenase activity
L1871_12425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L1871_12430	COG1024	Enoyl-CoA hydratase
L1871_12455	COG1584	GPR1 FUN34 yaaH family protein
L1871_12460	COG3228	Belongs to the MtfA family
L1871_12470	COG1115	amino acid carrier protein
L1871_12475	COG1024	Enoyl-CoA hydratase
L1871_12490	COG3162	membrane
L1871_12495	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L1871_12500	COG0488	(ABC) transporter
L1871_12505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L1871_12510	COG0776	regulation of translation
L1871_12515	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
L1871_12520	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
L1871_12525	COG0740	serine-type endopeptidase activity
L1871_12530	COG0544	peptidyl-prolyl cis-trans isomerase activity
L1871_12540	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
L1871_12545	COG4591	ABC-type transport system involved in lipoprotein release permease component
L1871_12550	COG1136	(ABC) transporter
L1871_12555	COG4591	ABC-type transport system involved in lipoprotein release permease component
L1871_12565	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L1871_12570	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
L1871_12585	COG0697	spore germination
L1871_12600	COG2062	phosphohistidine phosphatase, SixA
L1871_12620	COG1846	Transcriptional regulator
L1871_12645	COG5290	Psort location Cytoplasmic, score
L1871_12660	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L1871_12660	COG0519	Catalyzes the synthesis of GMP from XMP
L1871_12665	COG0516	GMP reductase activity
L1871_12665	COG0517	IMP dehydrogenase activity
L1871_12675	COG0366	Alpha amylase catalytic
L1871_12675	COG1874	Beta-galactosidase
L1871_12685	COG1570	exodeoxyribonuclease VII activity
L1871_12715	COG2154	pterin-4-alpha-carbinolamine dehydratase
L1871_12725	COG3768	UPF0283 membrane protein
L1871_12730	COG3106	COG3106 Predicted ATPase
L1871_12745	COG1842	Phage shock protein A
L1871_12750	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
L1871_12765	COG4171	peptide transport system, permease
L1871_12775	COG4172	Belongs to the ABC transporter superfamily
L1871_12785	COG1609	Transcriptional regulator
L1871_12790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L1871_12790	COG1263	PTS System
L1871_12795	COG2723	6-phospho-beta-galactosidase activity
L1871_12800	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
L1871_12805	COG1286	toxin biosynthetic process
L1871_12810	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
L1871_12815	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L1871_12820	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L1871_12825	COG0531	amino acid
L1871_12825	COG1674	ftsk spoiiie
L1871_12835	COG0686	Belongs to the AlaDH PNT family
L1871_12840	COG0492	ferredoxin-NADP+ reductase activity
L1871_12845	COG3706	GGDEF domain
L1871_12850	COG3134	Outer membrane lipoprotein
L1871_12855	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
L1871_12860	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
L1871_12865	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
L1871_12870	COG0542	response to heat
L1871_12875	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
L1871_12880	COG1278	Cold shock
L1871_12885	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
L1871_12905	COG1944	ATP diphosphatase activity
L1871_12910	COG2116	formate transmembrane transporter activity
L1871_12915	COG1882	Formate acetyltransferase
L1871_12920	COG2983	Belongs to the UPF0260 family
L1871_12950	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
L1871_12955	COG0045	succinate-CoA ligase (ADP-forming) activity
L1871_12960	COG0508	dehydrogenase complex catalyzes the overall conversion of
L1871_12965	COG0567	Dehydrogenase, E1 component
L1871_12980	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
L1871_12985	COG2009	succinate dehydrogenase
L1871_13005	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L1871_13010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L1871_13010	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
L1871_13020	COG3069	C4-dicarboxylate transmembrane transporter activity
L1871_13035	COG1451	nucleotide metabolic process
L1871_13050	COG0254	rRNA binding
L1871_13055	COG0257	Belongs to the bacterial ribosomal protein bL36 family
L1871_13065	COG1172	Belongs to the binding-protein-dependent transport system permease family
L1871_13070	COG1129	ABC transporter
L1871_13075	COG1879	ABC-type sugar transport system periplasmic component
L1871_13080	COG1069	ribulokinase activity
L1871_13090	COG2160	L-arabinose isomerase activity
L1871_13100	COG0556	nucleotide-excision repair
L1871_13110	COG0436	Aminotransferase
L1871_13115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L1871_13130	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
L1871_13130	COG0392	lysyltransferase activity
L1871_13135	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L1871_13145	COG0469	pyruvate kinase activity
L1871_13155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L1871_13155	COG1263	PTS System
L1871_13160	COG1874	Beta-galactosidase
L1871_13165	COG3867	Arabinogalactan endo-beta-1,4-galactanase
L1871_13170	COG3833	ABC-type maltose transport systems, permease component
L1871_13175	COG1175	transmembrane transport
L1871_13180	COG2182	Extracellular solute-binding protein
L1871_13215	COG4580	involved in the transport of maltose and maltodextrins
L1871_13220	COG1609	Transcriptional regulator
L1871_13225	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L1871_13230	COG1085	galactose-1-phosphate uridylyltransferase
L1871_13235	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
L1871_13245	COG0625	glutathione transferase activity
L1871_13255	COG2801	Transposase and inactivated derivatives
L1871_13265	COG0483	inositol monophosphate 1-phosphatase activity
L1871_13280	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L1871_13285	COG2056	Na+-H+ antiporter family
L1871_13290	COG2814	Major facilitator Superfamily
L1871_13295	COG0583	DNA-binding transcription factor activity
L1871_13300	COG5001	Diguanylate cyclase
L1871_13320	COG2050	protein possibly involved in aromatic compounds catabolism
L1871_13330	COG0247	lactate metabolic process
L1871_13330	COG0277	FAD linked oxidase domain protein
L1871_13340	COG1253	flavin adenine dinucleotide binding
L1871_13345	COG1902	pentaerythritol trinitrate reductase activity
L1871_13355	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L1871_13360	COG0647	UMP catabolic process
L1871_13370	COG0367	asparagine synthase
L1871_13385	COG0625	glutathione transferase activity
L1871_13395	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
L1871_13410	COG0564	pseudouridine synthase activity
L1871_13415	COG5001	Diguanylate cyclase
L1871_13425	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
L1871_13460	COG0670	Belongs to the BI1 family
L1871_13470	COG1289	transmembrane transporter activity
L1871_13475	COG2920	part of a sulfur-relay system
L1871_13480	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
L1871_13485	COG0285	dihydrofolate synthase activity
L1871_13490	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
L1871_13495	COG0101	tRNA pseudouridine synthase activity
L1871_13505	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
L1871_13510	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L1871_13520	COG1464	Belongs to the NlpA lipoprotein family
L1871_13545	COG1119	ATPase activity
L1871_13550	COG0574	Belongs to the PEP-utilizing enzyme family
L1871_13550	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L1871_13555	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
L1871_13565	COG1113	amino acid transport
L1871_13615	COG1242	4 iron, 4 sulfur cluster binding
L1871_13620	COG0067	glutamate synthase
L1871_13620	COG0069	glutamate synthase activity
L1871_13620	COG0070	glutamate synthase
L1871_13625	COG0493	'glutamate synthase
L1871_13645	COG4104	PAAR repeat-containing protein
L1871_13655	COG0513	Belongs to the DEAD box helicase family
L1871_13685	COG3706	GGDEF domain
L1871_13690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L1871_13695	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
L1871_13700	COG0505	Belongs to the CarA family
L1871_13710	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
L1871_13720	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L1871_13725	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
L1871_13730	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L1871_13735	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
L1871_13740	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L1871_13745	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
L1871_13750	COG4139	cobalamin transport
L1871_13775	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
L1871_13785	COG0023	Translation Initiation Factor
L1871_13790	COG2119	membrane
L1871_13825	COG2199	diguanylate cyclase activity
L1871_13825	COG2203	Gaf domain
L1871_13845	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L1871_13855	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L1871_13860	COG2261	transglycosylase associated protein
L1871_13865	COG1309	transcriptional regulator
L1871_13870	COG0604	alcohol dehydrogenase
L1871_13885	COG0583	DNA-binding transcription factor activity
L1871_13935	COG0322	excinuclease ABC activity
L1871_13940	COG2197	response regulator
L1871_13945	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
L1871_13950	COG2835	tetraacyldisaccharide 4'-kinase activity
L1871_13955	COG1663	tetraacyldisaccharide 4'-kinase activity
L1871_13960	COG1132	(ABC) transporter
L1871_13980	COG0433	COG0433 Predicted ATPase
L1871_13985	COG1448	Aminotransferase
L1871_14000	COG1199	ATP-dependent helicase activity
L1871_14010	COG0123	including yeast histone deacetylase and acetoin utilization protein
L1871_14015	COG0477	Major facilitator Superfamily
L1871_14020	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
L1871_14025	COG1785	Belongs to the alkaline phosphatase family
L1871_14045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L1871_14050	COG3706	GGDEF domain
L1871_14055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L1871_14060	COG0765	amino acid transport
L1871_14065	COG1126	abc transporter atp-binding protein
L1871_14075	COG0531	amino acid
L1871_14090	COG1253	flavin adenine dinucleotide binding
L1871_14095	COG0704	Plays a role in the regulation of phosphate uptake
L1871_14100	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L1871_14105	COG0581	inorganic phosphate transmembrane transporter activity
L1871_14110	COG0573	inorganic phosphate transmembrane transporter activity
L1871_14115	COG0590	tRNA wobble adenosine to inosine editing
L1871_14130	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L1871_14150	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
L1871_14155	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
L1871_14160	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L1871_14165	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L1871_14190	COG2716	regulation of RNA biosynthetic process
L1871_14195	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
L1871_14205	COG2239	Acts as a magnesium transporter
L1871_14220	COG3951	Flagellar rod assembly protein muramidase FlgJ
L1871_14220	COG1705	Flagellar rod assembly protein muramidase FlgJ
L1871_14225	COG1706	bacterial-type flagellum-dependent cell motility
L1871_14230	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
L1871_14245	COG1749	Flagellar hook protein flgE
L1871_14260	COG1815	bacterial-type flagellum-dependent cell motility
L1871_14265	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
L1871_14270	COG0835	chemotaxis
L1871_14270	COG0784	Response regulator, receiver
L1871_14275	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
L1871_14290	COG0622	Phosphoesterase
L1871_14295	COG4166	transmembrane transport
L1871_14310	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
L1871_14320	COG0697	spore germination
L1871_14325	COG4166	transmembrane transport
L1871_14350	COG1278	Cold shock
L1871_14390	COG3132	Protein of unknown function, DUF480
L1871_14400	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
L1871_14425	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
L1871_14430	COG1215	transferase activity, transferring glycosyl groups
L1871_14440	COG0438	transferase activity, transferring glycosyl groups
L1871_14465	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
L1871_14470	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
L1871_14475	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
L1871_14500	COG1737	Transcriptional regulator
L1871_14505	COG0469	pyruvate kinase activity
L1871_14520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L1871_14525	COG1960	acyl-CoA dehydrogenase activity
L1871_14535	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
L1871_14580	COG0419	ATPase involved in DNA repair
L1871_14600	COG2135	peptidase activity
L1871_14605	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L1871_14610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L1871_14665	COG3039	Transposase
L1871_14690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L1871_14695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L1871_14700	COG1309	transcriptional regulator
L1871_14715	COG1946	Acyl-CoA thioesterase
L1871_14730	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
L1871_14740	COG0009	L-threonylcarbamoyladenylate synthase
L1871_14745	COG0613	PHP domain protein
L1871_14750	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L1871_14755	COG0512	Glutamine amidotransferase of anthranilate synthase
L1871_14755	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L1871_14760	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L1871_14765	COG0135	phosphoribosylanthranilate isomerase activity
L1871_14765	COG0134	indole-3-glycerol-phosphate synthase activity
L1871_14770	COG0133	tryptophan synthase activity
L1871_14775	COG0159	tryptophan synthase activity
L1871_14830	COG4521	taurine ABC transporter
L1871_14835	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
L1871_14840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L1871_14845	COG2175	clavaminate synthase activity
L1871_14850	COG5507	3-demethylubiquinone-9 3-methyltransferase
L1871_14855	COG2814	Major facilitator Superfamily
L1871_14860	COG0109	protoheme IX farnesyltransferase activity
L1871_14865	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
L1871_14870	COG1845	cytochrome c oxidase, subunit III
L1871_14875	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L1871_14880	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L1871_14885	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L1871_14890	COG0583	DNA-binding transcription factor activity
L1871_14910	COG1846	Transcriptional regulator
L1871_14925	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
L1871_14940	COG0745	RESPONSE REGULATOR receiver
L1871_14950	COG0708	Exodeoxyribonuclease III
L1871_14960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L1871_14965	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L1871_14980	COG0095	Lipoate-protein ligase
L1871_15000	COG2391	methyltransferase activity
L1871_15020	COG0446	pyridine nucleotide-disulphide oxidoreductase
L1871_15030	COG1285	pathogenesis
L1871_15060	COG0484	heat shock protein binding
L1871_15065	COG0443	Heat shock 70 kDa protein
L1871_15075	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
L1871_15080	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L1871_15085	COG3706	GGDEF domain
L1871_15090	COG0497	DNA recombination
L1871_15100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L1871_15105	COG1136	(ABC) transporter
L1871_15105	COG0577	efflux transmembrane transporter activity
L1871_15110	COG1538	Outer membrane efflux protein
L1871_15115	COG2375	cellular response to nickel ion
L1871_15135	COG2916	Histone family protein nucleoid-structuring protein H-NS
L1871_15140	COG0583	DNA-binding transcription factor activity
L1871_15145	COG3048	D-serine ammonia-lyase activity
L1871_15155	COG0538	isocitrate dehydrogenase activity
L1871_15190	COG0456	acetyltransferase
L1871_15195	COG1187	pseudouridine synthase activity
L1871_15205	COG0482	sulfurtransferase activity
L1871_15210	COG2915	High frequency lysogenization protein hflD homolog
L1871_15215	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L1871_15220	COG2850	peptidyl-arginine hydroxylation
L1871_15230	COG1196	nuclear chromosome segregation
L1871_15230	COG3264	Mechanosensitive ion channel
L1871_15265	COG0281	malic enzyme
L1871_15270	COG0746	molybdenum cofactor guanylyltransferase activity
L1871_15275	COG1763	Mo-molybdopterin cofactor biosynthetic process
L1871_15280	COG1289	transmembrane transporter activity
L1871_15285	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
L1871_15315	COG3220	belongs to the UPF0276 family
L1871_15325	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L1871_15360	COG4319	ketosteroid isomerase
L1871_15365	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L1871_15370	COG0083	homoserine kinase activity
L1871_15380	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
L1871_15385	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
L1871_15400	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L1871_15410	COG0745	RESPONSE REGULATOR receiver
L1871_15425	COG4988	ABC transporter
L1871_15430	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
L1871_15450	COG1720	tRNA m6t6A37 methyltransferase activity
L1871_15465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L1871_15470	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L1871_15475	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L1871_15485	COG2190	(PTS) system
L1871_15490	COG3038	cytochrome b561
L1871_15505	COG0420	3'-5' exonuclease activity
L1871_15510	COG1247	-acetyltransferase
L1871_15515	COG2974	May be involved in recombination
L1871_15530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L1871_15530	COG4651	solute:proton antiporter activity
L1871_15565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L1871_15570	COG1396	sequence-specific DNA binding
L1871_15570	COG1917	Cupin 2, conserved barrel domain protein
L1871_15575	COG1012	belongs to the aldehyde dehydrogenase family
L1871_15590	COG0531	amino acid
L1871_15595	COG0531	amino acid
L1871_15605	COG1283	sodium-dependent phosphate transmembrane transporter activity
L1871_15615	COG3384	dioxygenase
L1871_15620	COG2205	protein histidine kinase activity
L1871_15620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L1871_15645	COG2205	protein histidine kinase activity
L1871_15645	COG0784	Response regulator, receiver
L1871_15655	COG1388	LysM domain
L1871_15655	COG1376	ErfK ybiS ycfS ynhG family protein
L1871_15670	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
L1871_15675	COG0791	NLP P60 protein
L1871_15685	COG3118	belongs to the thioredoxin family
L1871_15695	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L1871_15700	COG0788	formyltetrahydrofolate deformylase activity
L1871_15725	COG0739	heme binding
L1871_15725	COG0741	lytic transglycosylase activity
L1871_15725	COG1196	nuclear chromosome segregation
L1871_15735	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
L1871_15740	COG0673	inositol 2-dehydrogenase activity
L1871_15785	COG1032	radical SAM domain protein
L1871_15790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L1871_15805	COG3706	GGDEF domain
L1871_15810	COG1752	Esterase of the alpha-beta hydrolase superfamily
L1871_15815	COG0733	neurotransmitter:sodium symporter activity
L1871_15865	COG0281	malic enzyme
L1871_15870	COG2207	Transcriptional regulator
L1871_15895	COG0095	Lipoate-protein ligase
L1871_15900	COG1115	amino acid carrier protein
L1871_15905	COG0019	diaminopimelate decarboxylase activity
L1871_15915	COG0678	peroxiredoxin activity
L1871_15920	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
L1871_15930	COG1126	abc transporter atp-binding protein
L1871_15935	COG0765	amino acid transport
L1871_15940	COG4597	amino acid ABC transporter
L1871_15945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L1871_15960	COG1131	(ABC) transporter
L1871_15965	COG0545	Peptidyl-prolyl cis-trans isomerase
L1871_15970	COG3142	Participates in the control of copper homeostasis
L1871_15985	COG4783	chaperone-mediated protein folding
L1871_15995	COG5002	protein histidine kinase activity
L1871_16000	COG0745	RESPONSE REGULATOR receiver
L1871_16005	COG0346	lactoylglutathione lyase activity
L1871_16010	COG3706	GGDEF domain
L1871_16015	COG3284	Transcriptional regulator
L1871_16030	COG0697	spore germination
L1871_16040	COG0667	Aldo Keto reductase
L1871_16055	COG3290	protein histidine kinase activity
L1871_16065	COG1566	PFAM secretion protein HlyD family protein
L1871_16090	COG0602	queuosine metabolic process
L1871_16095	COG1328	CTP reductase activity
L1871_16115	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
L1871_16120	COG3115	cell septum assembly
L1871_16125	COG1196	nuclear chromosome segregation
L1871_16135	COG2860	membrane
L1871_16145	COG3108	Peptidase M15
L1871_16150	COG2989	Protein conserved in bacteria
L1871_16165	COG0463	Glycosyl transferase, family 2
L1871_16180	COG0366	Alpha amylase catalytic
L1871_16215	COG3706	GGDEF domain
L1871_16220	COG0037	tRNA processing
L1871_16225	COG3590	peptidase
L1871_16235	COG0488	(ABC) transporter
L1871_16245	COG0531	amino acid
L1871_16250	COG0814	amino acid
L1871_16270	COG0825	malonyl-CoA metabolic process
L1871_16280	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
L1871_16285	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L1871_16290	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L1871_16295	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
L1871_16300	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L1871_16315	COG0750	zinc metalloprotease
L1871_16320	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
L1871_16325	COG0575	Belongs to the CDS family
L1871_16330	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L1871_16335	COG0233	cytoplasmic translational termination
L1871_16340	COG0528	UMP kinase activity
L1871_16345	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
L1871_16350	COG0052	Belongs to the universal ribosomal protein uS2 family
L1871_16355	COG0024	Methionine aminopeptidase
L1871_16360	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
L1871_16365	COG2171	N-acyltransferase activity
L1871_16375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L1871_16375	COG1263	PTS System
L1871_16400	COG0564	pseudouridine synthase activity
L1871_16405	COG3098	single-species biofilm formation
L1871_16430	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
L1871_16440	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
L1871_16440	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
L1871_16455	COG1611	Belongs to the LOG family
L1871_16460	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L1871_16465	COG0473	3-isopropylmalate dehydrogenase activity
L1871_16475	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
L1871_16490	COG0583	DNA-binding transcription factor activity
L1871_16495	COG0840	transmembrane signaling receptor activity
L1871_16500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L1871_16515	COG1477	protein flavinylation
L1871_16520	COG2871	sodium ion transport
L1871_16525	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
L1871_16530	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
L1871_16535	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
L1871_16540	COG1805	sodium ion transport
L1871_16545	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
L1871_16550	COG0271	Belongs to the BolA IbaG family
L1871_16555	COG2813	Specifically methylates the guanine in position
L1871_16565	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L1871_16575	COG2211	Major facilitator Superfamily
L1871_16580	COG3248	Nucleoside-binding outer membrane protein
L1871_16585	COG1666	GTP binding
L1871_16620	COG4104	PAAR repeat-containing protein
L1871_16640	COG2771	luxR family
L1871_16645	COG0659	secondary active sulfate transmembrane transporter activity
L1871_16650	COG5002	protein histidine kinase activity
L1871_16655	COG0745	RESPONSE REGULATOR receiver
L1871_16660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L1871_16665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L1871_16685	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L1871_16695	COG1151	hydroxylamine reductase activity
L1871_16700	COG0783	Belongs to the Dps family
L1871_16725	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
L1871_16740	COG0300	oxidoreductase activity
L1871_16750	COG0415	Belongs to the DNA photolyase family
L1871_16755	COG0789	Transcriptional regulator
L1871_16760	COG3272	Protein of unknown function (DUF1722)
L1871_16785	COG1605	Chorismate mutase
L1871_16785	COG0077	Prephenate dehydratase
L1871_16815	COG5377	YqaJ viral recombinase family
L1871_16825	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L1871_16830	COG3041	Addiction module toxin RelE StbE family
L1871_16840	COG1879	ABC-type sugar transport system periplasmic component
L1871_16865	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L1871_16925	COG2003	Belongs to the UPF0758 family
L1871_16950	COG4133	protoheme IX ABC transporter activity
L1871_16960	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
L1871_17015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
L1871_17050	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L1871_17100	COG1349	DNA-binding transcription factor activity
L1871_17105	COG2084	Dehydrogenase
L1871_17115	COG0235	Class ii aldolase
L1871_17120	COG3622	Belongs to the hyi family
L1871_17125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L1871_17130	COG2610	gluconate transmembrane transporter activity
L1871_17150	COG0300	oxidoreductase activity
L1871_17175	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
L1871_17195	COG3813	Protein conserved in bacteria
L1871_17205	COG0826	peptidase U32
L1871_17210	COG1280	lysine exporter protein (LysE YggA)
L1871_17220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L1871_17245	COG2199	diguanylate cyclase activity
L1871_17245	COG2200	EAL domain
L1871_17245	COG2203	Gaf domain
L1871_17290	COG1566	PFAM secretion protein HlyD family protein
L1871_17300	COG0114	fumarate hydratase activity
L1871_17310	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L1871_17310	COG0506	proline dehydrogenase activity
L1871_17310	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L1871_17315	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L1871_17330	COG0737	Belongs to the 5'-nucleotidase family
L1871_17350	COG2204	response regulator
L1871_17355	COG0545	Peptidyl-prolyl cis-trans isomerase
L1871_17365	COG2900	Belongs to the SlyX family
L1871_17370	COG1047	Peptidyl-prolyl cis-trans
L1871_17375	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
L1871_17385	COG0835	chemotaxis
L1871_17385	COG0784	Response regulator, receiver
L1871_17390	COG0429	hydrolase of the alpha beta-hydrolase fold
L1871_17395	COG5001	Diguanylate cyclase
L1871_17395	COG4251	negative regulation of phosphorylation
L1871_17395	COG3706	GGDEF domain
L1871_17395	COG2203	Gaf domain
L1871_17400	COG3089	Belongs to the UPF0270 family
L1871_17405	COG3954	Phosphoribulokinase
L1871_17420	COG1765	OsmC-like protein
L1871_17430	COG2226	methyltransferase
L1871_17440	COG2205	protein histidine kinase activity
L1871_17440	COG2202	Pas domain
L1871_17445	COG2814	Major facilitator Superfamily
L1871_17470	COG0748	coenzyme F420 binding
L1871_17475	COG3721	Heme iron utilization protein
L1871_17485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L1871_17510	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
L1871_17520	COG0463	Glycosyl transferase, family 2
L1871_17525	COG0741	lytic transglycosylase activity
L1871_17540	COG3778	Protein conserved in bacteria
L1871_17545	COG3299	homolog of phage Mu protein gp47
L1871_17585	COG4386	tail sheath protein
L1871_17625	COG0616	signal peptide processing
L1871_17640	COG1802	Transcriptional regulator
L1871_17640	COG4626	Terminase
L1871_17690	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L1871_17795	COG1846	Transcriptional regulator
L1871_17885	COG0582	viral genome integration into host DNA
L1871_17890	COG0488	(ABC) transporter
L1871_17900	COG2252	PERMEase
L1871_17905	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
L1871_17910	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L1871_17915	COG3178	'Phosphotransferase
L1871_17920	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
L1871_17930	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
L1871_17935	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
L1871_17940	COG2967	ApaG domain
L1871_17945	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L1871_17960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L1871_17970	COG3314	Sporulation integral membrane protein YlbJ
L1871_17975	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
L1871_17980	COG0211	Belongs to the bacterial ribosomal protein bL27 family
L1871_17985	COG0261	This protein binds to 23S rRNA in the presence of protein L20
L1871_17990	COG0142	geranyltranstransferase activity
L1871_17995	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
L1871_18000	COG0330	HflC and HflK could
L1871_18005	COG0330	HflC and HflK could
L1871_18010	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L1871_18015	COG1923	regulation of RNA biosynthetic process
L1871_18020	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
L1871_18025	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
L1871_18035	COG0802	atpase or kinase
L1871_18040	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L1871_18040	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
L1871_18060	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L1871_18065	COG2011	ABC-type metal ion transport system permease component
L1871_18070	COG1464	Belongs to the NlpA lipoprotein family
L1871_18095	COG0784	Response regulator, receiver
L1871_18095	COG2205	protein histidine kinase activity
L1871_18110	COG0784	Response regulator, receiver
L1871_18110	COG2198	Histidine kinase
L1871_18110	COG5002	protein histidine kinase activity
L1871_18130	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
L1871_18145	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
L1871_18150	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
L1871_18155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L1871_18160	COG2716	regulation of RNA biosynthetic process
L1871_18165	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L1871_18170	COG3013	Belongs to the UPF0304 family
L1871_18180	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L1871_18185	COG0280	phosphate acetyltransferase
L1871_18185	COG0857	belongs to the CobB CobQ family
L1871_18190	COG0440	acetolactate synthase activity
L1871_18195	COG0028	Belongs to the TPP enzyme family
L1871_18220	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L1871_18225	COG0473	3-isopropylmalate dehydrogenase activity
L1871_18230	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
L1871_18235	COG0066	3-isopropylmalate dehydratase activity
L1871_18250	COG4143	(ABC) transporter
L1871_18255	COG1178	ABC-type Fe3 transport system permease component
L1871_18260	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
L1871_18265	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
L1871_18275	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L1871_18340	COG2205	protein histidine kinase activity
L1871_18345	COG0745	RESPONSE REGULATOR receiver
L1871_18350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L1871_18355	COG0577	efflux transmembrane transporter activity
L1871_18355	COG1136	(ABC) transporter
L1871_18365	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
L1871_18400	COG2199	diguanylate cyclase activity
L1871_18400	COG2203	Gaf domain
L1871_18405	COG0513	Belongs to the DEAD box helicase family
L1871_18415	COG2207	Transcriptional regulator
L1871_18415	COG1917	Cupin 2, conserved barrel domain protein
L1871_18450	COG3039	Transposase
L1871_18455	COG0529	Catalyzes the synthesis of activated sulfate
L1871_18460	COG0471	metal ion transport
L1871_18460	COG3273	potassium ion transport
L1871_18465	COG2895	sulfate adenylyltransferase (ATP) activity
L1871_18470	COG0175	sulfate reduction
L1871_18475	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L1871_18475	COG1648	precorrin-2 dehydrogenase activity
L1871_18480	COG0330	HflC and HflK could
L1871_18485	COG1585	Membrane protein implicated in regulation of membrane protease activity
L1871_18500	COG0673	inositol 2-dehydrogenase activity
L1871_18510	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
L1871_18515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L1871_18525	COG3036	rescue of stalled ribosome
L1871_18540	COG0138	bifunctional purine biosynthesis protein purh
L1871_18575	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
L1871_18580	COG0358	DNA primase activity
L1871_18585	COG1610	YqeY-like protein
L1871_18590	COG0828	Belongs to the bacterial ribosomal protein bS21 family
L1871_18595	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
L1871_18605	COG4942	peptidase
L1871_18605	COG1388	LysM domain
L1871_18610	COG1238	metal cluster binding
L1871_18615	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
L1871_18620	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
L1871_18625	COG0585	pseudouridine synthase activity
L1871_18630	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
L1871_18635	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
L1871_18640	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
L1871_18645	COG0148	phosphopyruvate hydratase activity
L1871_18650	COG0504	CTP synthase activity
L1871_18655	COG3956	TIGRFAM MazG family protein
L1871_18660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L1871_18665	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
L1871_18675	COG4807	Protein conserved in bacteria
L1871_18680	COG3023	N-Acetylmuramoyl-L-alanine amidase
L1871_18685	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
L1871_18690	COG1381	Involved in DNA repair and RecF pathway recombination
L1871_18700	COG0571	ribonuclease III activity
L1871_18705	COG0681	Belongs to the peptidase S26 family
L1871_18710	COG0481	GTPase activity
L1871_18730	COG1595	DNA-templated transcription, initiation
L1871_18735	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
L1871_18745	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
L1871_18750	COG0354	folic acid binding
L1871_18755	COG0583	DNA-binding transcription factor activity
L1871_18785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L1871_18795	COG0126	phosphoglycerate kinase activity
L1871_18800	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L1871_18805	COG1940	carbohydrate kinase activity
L1871_18810	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
L1871_18815	COG2816	NAD+ diphosphatase activity
L1871_18820	COG4991	sh3 domain protein
L1871_18825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L1871_18845	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
L1871_18850	COG1028	Short-chain dehydrogenase reductase Sdr
L1871_18865	COG1505	serine-type exopeptidase activity
L1871_18870	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L1871_18875	COG0765	amino acid transport
L1871_18880	COG0765	amino acid transport
L1871_18885	COG1126	abc transporter atp-binding protein
L1871_18890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L1871_18895	COG3174	membrane
L1871_18900	COG0110	maltose O-acetyltransferase activity
L1871_18930	COG1942	4-Oxalocrotonate Tautomerase
L1871_18940	COG0583	DNA-binding transcription factor activity
L1871_18945	COG0165	Argininosuccinate lyase
L1871_18950	COG0137	argininosuccinate synthase activity
L1871_18960	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
L1871_18965	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
L1871_18975	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
L1871_18990	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L1871_19025	COG0583	DNA-binding transcription factor activity
L1871_19030	COG1380	Effector of murein hydrolase LrgA
L1871_19035	COG1346	cytolysis
L1871_19040	COG0460	homoserine dehydrogenase
L1871_19040	COG0527	aspartate kinase activity
L1871_19045	COG0626	cystathionine gamma-synthase activity
L1871_19060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L1871_19065	COG0814	amino acid
L1871_19070	COG1218	3'(2'),5'-bisphosphate nucleotidase
L1871_19075	COG0494	nUDIX hydrolase
L1871_19080	COG1011	Hydrolase
L1871_19095	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L1871_19110	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
L1871_19120	COG3156	type II secretion system protein K
L1871_19130	COG4795	General secretion pathway protein
L1871_19135	COG2165	general secretion pathway protein
L1871_19145	COG2165	general secretion pathway protein
L1871_19150	COG1459	type II secretion system
L1871_19155	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L1871_19165	COG3031	protein transport across the cell outer membrane
L1871_19175	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
L1871_19180	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
L1871_19195	COG0456	acetyltransferase
L1871_19200	COG3133	Outer membrane lipoprotein
L1871_19205	COG3025	triphosphatase activity
L1871_19210	COG1392	Phosphate transport regulator
L1871_19215	COG0306	phosphate transporter
L1871_19220	COG0617	tRNA 3'-terminal CCA addition
L1871_19225	COG3267	Type II secretory pathway component ExeA
L1871_19225	COG3409	Peptidoglycan-binding domain 1 protein
L1871_19235	COG1194	a g-specific adenine glycosylase
L1871_19240	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
L1871_19255	COG3240	lipase activity
L1871_19265	COG3009	Protein conserved in bacteria
L1871_19270	COG3008	intermembrane lipid transfer
L1871_19270	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
L1871_19275	COG2995	paraquat-inducible protein a
L1871_19285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L1871_19290	COG5001	Diguanylate cyclase
L1871_19290	COG4251	negative regulation of phosphorylation
L1871_19290	COG3706	GGDEF domain
L1871_19290	COG2203	Gaf domain
L1871_19295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L1871_19300	COG2813	Specifically methylates the guanine in position
L1871_19305	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
L1871_19310	COG0297	glycogen (starch) synthase activity
L1871_19345	COG1757	Na H antiporter
L1871_19350	COG0583	DNA-binding transcription factor activity
L1871_19355	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
L1871_19360	COG3842	ATPase activity
L1871_19365	COG1176	ABC-type spermidine putrescine transport system, permease component I
L1871_19370	COG1177	transmembrane transport
L1871_19375	COG1012	belongs to the aldehyde dehydrogenase family
L1871_19380	COG0109	protoheme IX farnesyltransferase activity
L1871_19410	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
L1871_19420	COG1565	acr, cog1565
L1871_19420	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L1871_19425	COG1444	tRNA N-acetyltransferase activity
L1871_19445	COG1803	Methylglyoxal synthase
L1871_19460	COG0252	asparaginase activity
L1871_19470	COG1609	Transcriptional regulator
L1871_19495	COG1940	carbohydrate kinase activity
L1871_19500	COG1447	Phosphotransferase system cellobiose-specific component IIA
L1871_19505	COG2723	6-phospho-beta-galactosidase activity
L1871_19510	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L1871_19515	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L1871_19520	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L1871_19540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L1871_19540	COG1263	PTS System
L1871_19545	COG0366	Alpha amylase catalytic
L1871_19550	COG0110	maltose O-acetyltransferase activity
L1871_19555	COG1522	sequence-specific DNA binding
L1871_19605	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
L1871_19610	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
L1871_19625	COG0477	Major facilitator Superfamily
L1871_19630	COG0523	cobalamin synthesis protein
L1871_19640	COG1280	lysine exporter protein (LysE YggA)
L1871_19650	COG2200	EAL domain
L1871_19655	COG1049	propionate catabolic process, 2-methylcitrate cycle
L1871_19660	COG1752	Esterase of the alpha-beta hydrolase superfamily
L1871_19665	COG0840	transmembrane signaling receptor activity
L1871_19670	COG0840	transmembrane signaling receptor activity
L1871_19685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L1871_19690	COG0508	dehydrogenase complex catalyzes the overall conversion of
L1871_19695	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
L1871_19700	COG2186	Transcriptional regulator
L1871_19725	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L1871_19730	COG1459	type II secretion system
L1871_19735	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
L1871_19745	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
L1871_19750	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
L1871_19755	COG0494	nUDIX hydrolase
L1871_19765	COG0653	protein targeting
L1871_19775	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
L1871_19780	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L1871_19785	COG0849	cell division
L1871_19790	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L1871_19795	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
L1871_19800	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
L1871_19805	COG0772	Belongs to the SEDS family
L1871_19810	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
L1871_19815	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
L1871_19820	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L1871_19825	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L1871_19830	COG0768	penicillin binding
L1871_19835	COG3116	cell division
L1871_19840	COG0275	rRNA processing
L1871_19845	COG2001	Belongs to the MraZ family
L1871_19855	COG0741	lytic transglycosylase activity
L1871_19855	COG1388	LysM domain
L1871_19865	COG1360	Flagellar Motor Protein
L1871_19870	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
L1871_19875	COG1191	sigma factor activity
L1871_19900	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
L1871_19905	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
L1871_19910	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
L1871_19915	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
L1871_19930	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
L1871_19935	COG1256	bacterial-type flagellum assembly
L1871_19935	COG4786	Flagellar basal body rod
L1871_19945	COG1706	bacterial-type flagellum-dependent cell motility
L1871_19950	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
L1871_19955	COG4786	Flagellar basal body rod
L1871_19965	COG1749	Flagellar hook protein flgE
L1871_19980	COG1815	bacterial-type flagellum-dependent cell motility
L1871_20015	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L1871_20025	COG1677	Flagellar hook-basal body complex protein FliE
L1871_20050	COG1987	bacterial-type flagellum assembly
L1871_20075	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
L1871_20080	COG3107	peptidoglycan biosynthetic process
L1871_20085	COG0792	nuclease activity
L1871_20090	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
L1871_20095	COG2823	Periplasmic or secreted lipoprotein
L1871_20100	COG2969	positive regulation of protein catabolic process
L1871_20105	COG0625	glutathione transferase activity
L1871_20110	COG2857	Cytochrome c1
L1871_20115	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
L1871_20120	COG0723	plastoquinol--plastocyanin reductase activity
L1871_20125	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L1871_20130	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
L1871_20135	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
L1871_20145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L1871_20150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L1871_20180	COG3964	amidohydrolase
L1871_20200	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L1871_20205	COG1660	Displays ATPase and GTPase activities
L1871_20210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
L1871_20220	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
L1871_20225	COG1137	ATPase activity
L1871_20230	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
L1871_20240	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
L1871_20245	COG0517	IMP dehydrogenase activity
L1871_20245	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
L1871_20250	COG1127	ABC transporter
L1871_20255	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L1871_20260	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
L1871_20265	COG2854	intermembrane phospholipid transfer
L1871_20275	COG5007	Belongs to the BolA IbaG family
L1871_20280	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L1871_20305	COG0312	modulator of DNA gyrase
L1871_20310	COG3028	Belongs to the UPF0307 family
L1871_20320	COG2926	Belongs to the UPF0265 family
L1871_20350	COG1396	sequence-specific DNA binding
L1871_20355	COG3135	benzoate transporter
L1871_20385	COG3047	cAMP biosynthetic process
L1871_20390	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L1871_20395	COG2197	response regulator
L1871_20415	COG1278	Cold shock
L1871_20445	COG3706	GGDEF domain
L1871_20450	COG0347	Belongs to the P(II) protein family
L1871_20455	COG0004	ammonium transporteR
L1871_20465	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L1871_20470	COG1074	ATP-dependent DNA helicase activity
L1871_20475	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
L1871_20480	COG2259	Doxx family
L1871_20485	COG1741	Belongs to the pirin family
L1871_20495	COG0583	DNA-binding transcription factor activity
L1871_20520	COG1175	transmembrane transport
L1871_20530	COG3842	ATPase activity
L1871_20560	COG0456	acetyltransferase
L1871_20565	COG0753	catalase activity
L1871_20585	COG0494	nUDIX hydrolase
L1871_20590	COG0628	permease
L1871_20600	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
L1871_20605	COG2252	PERMEase
L1871_20610	COG2376	Dihydroxyacetone kinase
L1871_20615	COG1461	Dihydroxyacetone kinase
L1871_20630	COG0583	DNA-binding transcription factor activity
L1871_20635	COG2957	Belongs to the agmatine deiminase family
L1871_20650	COG2957	Belongs to the agmatine deiminase family
L1871_20685	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
L1871_20690	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
L1871_20695	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
L1871_20700	COG0049	tRNA binding
L1871_20705	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
L1871_20710	COG2168	tRNA wobble position uridine thiolation
L1871_20720	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
L1871_20725	COG0251	oxidation-reduction process
L1871_20730	COG2964	Protein conserved in bacteria
L1871_20735	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
L1871_20740	COG0085	RNA polymerase activity
L1871_20745	COG0222	ribosome binding
L1871_20750	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
L1871_20755	COG0081	regulation of translation
L1871_20760	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
L1871_20765	COG0250	Participates in transcription elongation, termination and antitermination
L1871_20780	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
L1871_20805	COG0812	UDP-N-acetylmuramate dehydrogenase activity
L1871_20810	COG0569	domain protein
L1871_20815	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L1871_20820	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
L1871_20825	COG3005	denitrification pathway
L1871_20830	COG0243	molybdopterin cofactor binding
L1871_20865	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
L1871_20875	COG2204	response regulator
L1871_20885	COG2205	protein histidine kinase activity
L1871_20905	COG0516	GMP reductase activity
L1871_20905	COG0517	IMP dehydrogenase activity
L1871_20915	COG1522	sequence-specific DNA binding
L1871_20920	COG2502	aspartate--ammonia ligase
L1871_20930	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
L1871_20935	COG0542	response to heat
L1871_20945	COG0564	pseudouridine synthase activity
L1871_20950	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L1871_20955	COG3681	Belongs to the UPF0597 family
L1871_20960	COG2964	Protein conserved in bacteria
L1871_20970	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
L1871_20975	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
L1871_20980	COG1979	alcohol dehydrogenase
L1871_20985	COG2207	Transcriptional regulator
L1871_20990	COG3040	lipid binding
L1871_21025	COG0540	Belongs to the ATCase OTCase family
L1871_21030	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
L1871_21035	COG1438	arginine binding
L1871_21040	COG1288	antiporter activity
L1871_21045	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
L1871_21100	COG3250	beta-galactosidase activity
L1871_21105	COG1609	Transcriptional regulator
L1871_21110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L1871_21120	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
L1871_21125	COG2017	converts alpha-aldose to the beta-anomer
L1871_21130	COG0667	Aldo Keto reductase
L1871_21135	COG1968	undecaprenyl-diphosphatase activity
L1871_21140	COG3806	Anti-sigma factor
L1871_21145	COG1595	DNA-templated transcription, initiation
L1871_21165	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
L1871_21170	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
L1871_21175	COG0477	Major facilitator Superfamily
L1871_21190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L1871_21195	COG1131	(ABC) transporter
L1871_21200	COG0842	Transport permease protein
L1871_21205	COG0842	Transport permease protein
L1871_21210	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L1871_21220	COG2116	formate transmembrane transporter activity
L1871_21225	COG1648	precorrin-2 dehydrogenase activity
L1871_21225	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L1871_21230	COG2239	Acts as a magnesium transporter
L1871_21235	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L1871_21240	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
L1871_21250	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
L1871_21260	COG0514	ATP-dependent DNA helicase (RecQ)
L1871_21265	COG2050	protein possibly involved in aromatic compounds catabolism
L1871_21280	COG2258	MOSC domain
L1871_21285	COG1177	transmembrane transport
L1871_21290	COG1176	ABC-type spermidine putrescine transport system, permease component I
L1871_21295	COG3842	ATPase activity
L1871_21315	COG0174	glutamine synthetase
L1871_21335	COG3045	CreA protein
L1871_21340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
L1871_21345	COG0443	Heat shock 70 kDa protein
L1871_21360	COG0366	Alpha amylase catalytic
L1871_21370	COG4310	Domain of unknown function (DUF2172)
L1871_21400	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
L1871_21405	COG0745	RESPONSE REGULATOR receiver
L1871_21415	COG2205	protein histidine kinase activity
L1871_21430	COG0281	malic enzyme
L1871_21435	COG0702	epimerase
L1871_21440	COG0254	rRNA binding
L1871_21445	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L1871_21450	COG1309	transcriptional regulator
L1871_21470	COG0129	dihydroxy-acid dehydratase activity
L1871_21480	COG3978	acetolactate synthase activity
L1871_21490	COG0606	chelatase, subunit chli
L1871_21495	COG0204	Acyl-transferase
L1871_21500	COG0204	Acyl-transferase
L1871_21505	COG1683	Conserved Protein
L1871_21515	COG1335	isochorismatase
L1871_21525	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L1871_21530	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L1871_21540	COG3084	Protein conserved in bacteria
L1871_21545	COG5001	Diguanylate cyclase
L1871_21545	COG4251	negative regulation of phosphorylation
L1871_21545	COG3706	GGDEF domain
L1871_21545	COG2203	Gaf domain
L1871_21560	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
L1871_21565	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
L1871_21570	COG1561	YicC-like family, N-terminal region
L1871_21595	COG1519	Transferase
L1871_21600	COG0859	PFAM glycosyl transferase family 9
L1871_21605	COG0463	Glycosyl transferase, family 2
L1871_21610	COG0859	PFAM glycosyl transferase family 9
L1871_21615	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
L1871_21620	COG2990	Protein conserved in bacteria
L1871_21625	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
L1871_21635	COG0267	Belongs to the bacterial ribosomal protein bL33 family
L1871_21640	COG0227	Belongs to the bacterial ribosomal protein bL28 family
L1871_21645	COG2003	Belongs to the UPF0758 family
L1871_21650	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L1871_21655	COG0756	dUTP diphosphatase activity
L1871_21660	COG1309	transcriptional regulator
L1871_21665	COG0668	transmembrane transport
L1871_21675	COG0166	Belongs to the GPI family
L1871_21680	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
L1871_21685	COG0583	DNA-binding transcription factor activity
L1871_21695	COG0045	succinate-CoA ligase (ADP-forming) activity
L1871_21695	COG1042	CoA-binding domain protein
L1871_21695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L1871_21720	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
L1871_21725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L1871_21730	COG1739	Uncharacterized protein family UPF0029
L1871_21735	COG0006	proline dipeptidase activity
L1871_21740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L1871_21745	COG1250	3-hydroxyacyl-CoA dehydrogenase
L1871_21745	COG1024	Enoyl-CoA hydratase
L1871_21750	COG0183	Belongs to the thiolase family
L1871_21765	COG1653	transport
L1871_21785	COG0425	Belongs to the sulfur carrier protein TusA family
L1871_21805	COG2885	chlorophyll binding
L1871_21815	COG1335	isochorismatase
L1871_21820	COG2818	Glycosylase
L1871_21825	COG0752	glycyl-tRNA synthetase alpha subunit
L1871_21830	COG0751	glycine-tRNA ligase activity
L1871_21835	COG5001	Diguanylate cyclase
L1871_21835	COG2203	Gaf domain
L1871_21835	COG3706	GGDEF domain
L1871_21835	COG4251	negative regulation of phosphorylation
L1871_21850	COG0814	amino acid
L1871_21855	COG0814	amino acid
L1871_21860	COG3033	Beta-eliminating lyase
L1871_21870	COG0348	domain, Protein
L1871_21880	COG0446	pyridine nucleotide-disulphide oxidoreductase
L1871_21885	COG0426	domain, Protein
L1871_21885	COG1773	rubredoxin
L1871_21890	COG3604	Transcriptional regulator
L1871_21895	COG1609	Transcriptional regulator
L1871_21935	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L1871_21950	COG2960	long-chain fatty acid transporting porin activity
L1871_21960	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
L1871_21975	COG3118	belongs to the thioredoxin family
L1871_21980	COG0513	Belongs to the DEAD box helicase family
L1871_21985	COG0248	Ppx GppA phosphatase
L1871_21995	COG0742	ribosomal rna small subunit methyltransferase
L1871_22005	COG0339	signal peptide processing
L1871_22015	COG0084	hydrolase, TatD family'
L1871_22020	COG0805	protein transport
L1871_22025	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
L1871_22030	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
L1871_22035	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L1871_22040	COG3165	ubiquinone biosynthetic process from chorismate
L1871_22050	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
L1871_22110	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
L1871_22115	COG0848	biopolymer transport protein
L1871_22120	COG0811	peptide transport
L1871_22125	COG0811	peptide transport
L1871_22135	COG2771	luxR family
L1871_22140	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L1871_22145	COG1349	DNA-binding transcription factor activity
L1871_22150	COG0745	RESPONSE REGULATOR receiver
L1871_22155	COG2205	protein histidine kinase activity
L1871_22165	COG4452	Inner membrane protein CreD
L1871_22170	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
L1871_22175	COG0355	proton-transporting ATP synthase activity, rotational mechanism
L1871_22180	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
L1871_22185	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
L1871_22190	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
L1871_22195	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
L1871_22200	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
L1871_22210	COG0356	it plays a direct role in the translocation of protons across the membrane
L1871_22220	COG1475	DNA binding
L1871_22225	COG1192	Involved in chromosome partitioning
L1871_22230	COG0357	Ribosomal RNA small subunit methyltransferase G
L1871_22235	COG0445	tRNA wobble uridine modification
L1871_22240	COG0716	FMN binding
L1871_22245	COG4774	siderophore transport
L1871_22250	COG4615	Cyclic peptide transporter
L1871_22255	COG1120	ATPase activity
L1871_22260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L1871_22270	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
L1871_22275	COG0706	membrane insertase activity
L1871_22280	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
L1871_22285	COG0594	ribonuclease P activity
L1871_22290	COG0230	Belongs to the bacterial ribosomal protein bL34 family
L1871_22295	COG1126	abc transporter atp-binding protein
L1871_22365	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
L1871_22405	COG0419	ATPase involved in DNA repair
L1871_22450	COG3344	reverse transcriptase
L1871_22530	COG0776	regulation of translation
L1871_22550	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
L1871_22640	COG0358	DNA primase activity
L1871_22655	COG1923	regulation of RNA biosynthetic process
L1871_22685	COG5301	cellulose 1,4-beta-cellobiosidase activity
L1871_22825	COG1136	(ABC) transporter
L1871_22845	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L1871_22885	COG4974	Belongs to the 'phage' integrase family
L1871_22955	COG1937	Protein conserved in bacteria
L1871_22960	COG1230	cation diffusion facilitator family transporter
L1871_22965	COG0640	Transcriptional regulator
L1871_22970	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L1871_22975	COG3041	Addiction module toxin RelE StbE family
L1871_22990	COG3039	Transposase
L1871_23015	COG1192	Involved in chromosome partitioning
L1871_23055	COG3609	addiction module antidote protein, CC2985 family
L1871_23070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L1871_23080	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L1871_23095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L1871_23130	COG0583	DNA-binding transcription factor activity
L1871_23140	COG3041	Addiction module toxin RelE StbE family
L1871_23145	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L1871_23165	COG1192	Involved in chromosome partitioning
L1871_23200	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L1871_23215	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L1871_23220	COG3077	Addiction module antitoxin, RelB DinJ family
L1871_23275	COG4644	lycopene metabolic process
L1871_23280	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L1871_23360	COG1192	Involved in chromosome partitioning
L1871_23365	COG3077	Addiction module antitoxin, RelB DinJ family
L1871_23370	COG2026	Addiction module toxin, RelE StbE family
L1871_23395	COG0840	transmembrane signaling receptor activity
L1871_23495	COG4128	Pfam Zonular occludens toxin
L1871_23570	COG2336	PFAM SpoVT AbrB