locus-tag	class	description
NRK98_00010	COG4695	Portal protein
NRK98_00080	COG2932	Transcriptional regulator
NRK98_00090	COG4974	Belongs to the 'phage' integrase family
NRK98_00100	COG0004	ammonium transporteR
NRK98_00105	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NRK98_00120	COG2165	general secretion pathway protein
NRK98_00125	COG0084	hydrolase, TatD family'
NRK98_00130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRK98_00140	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NRK98_00145	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NRK98_00150	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NRK98_00155	COG0813	purine-nucleoside phosphorylase activity
NRK98_00160	COG5002	protein histidine kinase activity
NRK98_00160	COG3447	MASE1 domain protein
NRK98_00160	COG5001	Diguanylate cyclase
NRK98_00170	COG0560	Phosphoserine phosphatase
NRK98_00205	COG0776	regulation of translation
NRK98_00220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NRK98_00225	COG0735	belongs to the Fur family
NRK98_00250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NRK98_00255	COG0513	Belongs to the DEAD box helicase family
NRK98_00260	COG3022	response to hydroperoxide
NRK98_00275	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NRK98_00280	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NRK98_00285	COG0762	integral membrane protein
NRK98_00290	COG1872	DUF167
NRK98_00305	COG4166	transmembrane transport
NRK98_00315	COG0110	maltose O-acetyltransferase activity
NRK98_00325	COG1024	Enoyl-CoA hydratase
NRK98_00340	COG4221	oxidoreductase activity
NRK98_00345	COG0442	prolyl-tRNA aminoacylation
NRK98_00350	COG0840	transmembrane signaling receptor activity
NRK98_00355	COG0632	four-way junction helicase activity
NRK98_00360	COG2255	four-way junction helicase activity
NRK98_00365	COG1271	oxidase subunit
NRK98_00370	COG1294	oxidase, subunit
NRK98_00375	COG4890	Cyd operon protein YbgT
NRK98_00380	COG3790	cyd operon protein YbgE
NRK98_00385	COG0824	Thioesterase
NRK98_00390	COG0811	peptide transport
NRK98_00405	COG0823	Involved in the tonB-independent uptake of proteins
NRK98_00410	COG2885	chlorophyll binding
NRK98_00415	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
NRK98_00490	COG0840	transmembrane signaling receptor activity
NRK98_00495	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NRK98_00500	COG0676	glucose-6-phosphate 1-epimerase activity
NRK98_00505	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NRK98_00510	COG1640	4-alpha-glucanotransferase
NRK98_00515	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NRK98_00535	COG1051	belongs to the nudix hydrolase family
NRK98_00540	COG2130	NADP-dependent
NRK98_00545	COG1846	Transcriptional regulator
NRK98_00575	COG0561	phosphatase activity
NRK98_00590	COG0733	neurotransmitter:sodium symporter activity
NRK98_00600	COG0733	neurotransmitter:sodium symporter activity
NRK98_00625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRK98_00640	COG1794	racemase activity, acting on amino acids and derivatives
NRK98_00655	COG2731	YhcH YjgK YiaL family protein
NRK98_00665	COG0668	transmembrane transport
NRK98_00675	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NRK98_00715	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NRK98_00725	COG0488	(ABC) transporter
NRK98_00730	COG0517	IMP dehydrogenase activity
NRK98_00730	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NRK98_00735	COG1585	Membrane protein implicated in regulation of membrane protease activity
NRK98_00740	COG0330	HflC and HflK could
NRK98_00745	COG1648	precorrin-2 dehydrogenase activity
NRK98_00745	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NRK98_00750	COG0175	sulfate reduction
NRK98_00755	COG2895	sulfate adenylyltransferase (ATP) activity
NRK98_00760	COG3273	potassium ion transport
NRK98_00760	COG0471	metal ion transport
NRK98_00765	COG0529	Catalyzes the synthesis of activated sulfate
NRK98_00770	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NRK98_00775	COG0840	transmembrane signaling receptor activity
NRK98_00795	COG1136	(ABC) transporter
NRK98_00810	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
NRK98_00825	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NRK98_00830	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NRK98_00835	COG0163	prenyltransferase activity
NRK98_00850	COG1131	(ABC) transporter
NRK98_00855	COG0842	Transport permease protein
NRK98_00860	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
NRK98_00865	COG1924	4 iron, 4 sulfur cluster binding
NRK98_00885	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NRK98_00890	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NRK98_00905	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NRK98_00910	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NRK98_00915	COG1489	DNA binding
NRK98_00925	COG1643	Atp-dependent helicase
NRK98_00930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NRK98_00935	COG0346	lactoylglutathione lyase activity
NRK98_00945	COG2076	Multidrug Resistance protein
NRK98_00955	COG3437	response regulator, receiver
NRK98_00955	COG0784	Response regulator, receiver
NRK98_00965	COG0671	phosphoesterase, PA-phosphatase related
NRK98_00985	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NRK98_00990	COG0038	chloride channel
NRK98_01000	COG0316	Belongs to the HesB IscA family
NRK98_01030	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NRK98_01045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRK98_01075	COG0745	RESPONSE REGULATOR receiver
NRK98_01080	COG3104	oligopeptide transport
NRK98_01085	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NRK98_01090	COG1555	photosystem II stabilization
NRK98_01100	COG2350	Protein conserved in bacteria
NRK98_01105	COG2917	probably involved in intracellular septation
NRK98_01110	COG0076	glutamate decarboxylase activity
NRK98_01115	COG1272	protein, Hemolysin III
NRK98_01120	COG2985	domain, Protein
NRK98_01120	COG0569	domain protein
NRK98_01130	COG0784	Response regulator, receiver
NRK98_01130	COG0835	chemotaxis
NRK98_01135	COG2755	lipolytic protein G-D-S-L family
NRK98_01140	COG4181	ATPase activity
NRK98_01145	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
NRK98_01150	COG1090	epimerase
NRK98_01155	COG2200	EAL domain
NRK98_01160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRK98_01165	COG4935	Belongs to the peptidase S8 family
NRK98_01165	COG2234	aminopeptidase activity
NRK98_01170	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NRK98_01175	COG3171	Protein conserved in bacteria
NRK98_01180	COG2066	Belongs to the glutaminase family
NRK98_01185	COG2897	thiosulfate sulfurtransferase activity
NRK98_01190	COG1404	Belongs to the peptidase S8 family
NRK98_01200	COG1132	(ABC) transporter
NRK98_01225	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
NRK98_01230	COG3300	MHYT domain
NRK98_01230	COG5001	Diguanylate cyclase
NRK98_01250	COG4628	conserved protein (DUF2132)
NRK98_01255	COG0688	phosphatidylethanolamine metabolic process
NRK98_01260	COG1162	GTPase activity
NRK98_01265	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NRK98_01295	COG1278	Cold shock
NRK98_01305	COG0840	transmembrane signaling receptor activity
NRK98_01310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NRK98_01360	COG0848	biopolymer transport protein
NRK98_01365	COG0811	peptide transport
NRK98_01370	COG0811	peptide transport
NRK98_01385	COG4174	ABC transporter (Permease)
NRK98_01390	COG4239	(ABC) transporter, permease
NRK98_01400	COG0444	Belongs to the ABC transporter superfamily
NRK98_01405	COG4608	Belongs to the ABC transporter superfamily
NRK98_01410	COG2195	Cleaves the N-terminal amino acid of tripeptides
NRK98_01415	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
NRK98_01420	COG1073	alpha beta
NRK98_01460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRK98_01465	COG2313	pseudouridylate synthase activity
NRK98_01475	COG1858	cytochrome C peroxidase
NRK98_01510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NRK98_01515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NRK98_01540	COG2986	histidine ammonia-lyase
NRK98_01575	COG1028	Short-chain dehydrogenase reductase Sdr
NRK98_01580	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NRK98_01590	COG0521	Mo-molybdopterin cofactor biosynthetic process
NRK98_01600	COG2966	Psort location CytoplasmicMembrane, score
NRK98_01605	COG3610	response to peptide
NRK98_01615	COG4175	Glycine betaine
NRK98_01620	COG4176	ABC-type proline glycine betaine transport system permease component
NRK98_01625	COG2113	Glycine betaine
NRK98_01630	COG0175	sulfate reduction
NRK98_01635	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NRK98_01640	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NRK98_01645	COG0384	phenazine biosynthesis protein PhzF
NRK98_01650	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NRK98_01665	COG0786	glutamate:sodium symporter activity
NRK98_01670	COG0252	asparaginase activity
NRK98_01675	COG3139	Protein of unknown function (DUF1315)
NRK98_01695	COG0616	signal peptide processing
NRK98_01700	COG0446	pyridine nucleotide-disulphide oxidoreductase
NRK98_01700	COG1902	pentaerythritol trinitrate reductase activity
NRK98_01705	COG0778	Nitroreductase
NRK98_01720	COG2264	protein methyltransferase activity
NRK98_01725	COG0604	alcohol dehydrogenase
NRK98_01730	COG0583	DNA-binding transcription factor activity
NRK98_01735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRK98_01735	COG2190	(PTS) system
NRK98_01735	COG1263	PTS System
NRK98_01740	COG4145	pantothenate transmembrane transporter activity
NRK98_01745	COG3924	membrane
NRK98_01750	COG0439	Biotin carboxylase
NRK98_01755	COG0511	ligase activity, forming carbon-carbon bonds
NRK98_01760	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NRK98_01765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NRK98_01775	COG3300	MHYT domain
NRK98_01775	COG5001	Diguanylate cyclase
NRK98_01795	COG3381	protein complex oligomerization
NRK98_01805	COG3005	denitrification pathway
NRK98_01810	COG0745	RESPONSE REGULATOR receiver
NRK98_01820	COG1879	ABC-type sugar transport system periplasmic component
NRK98_01825	COG0784	Response regulator, receiver
NRK98_01825	COG2205	protein histidine kinase activity
NRK98_01825	COG2198	Histidine kinase
NRK98_01835	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NRK98_01850	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NRK98_01855	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NRK98_01855	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NRK98_01875	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NRK98_01880	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NRK98_01885	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NRK98_01890	COG4172	Belongs to the ABC transporter superfamily
NRK98_01900	COG0601	transmembrane transport
NRK98_01905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRK98_01910	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NRK98_01915	COG0142	geranyltranstransferase activity
NRK98_01920	COG1722	exodeoxyribonuclease VII activity
NRK98_01925	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NRK98_01930	COG1360	Flagellar Motor Protein
NRK98_01945	COG1534	Rna-binding protein
NRK98_01950	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NRK98_01960	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NRK98_01965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NRK98_01970	COG0149	triose-phosphate isomerase activity
NRK98_01975	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NRK98_01990	COG0779	Required for maturation of 30S ribosomal subunits
NRK98_01995	COG0195	Participates in both transcription termination and antitermination
NRK98_02000	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NRK98_02005	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NRK98_02010	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NRK98_02015	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NRK98_02020	COG1185	polyribonucleotide nucleotidyltransferase activity
NRK98_02025	COG2211	Major facilitator Superfamily
NRK98_02030	COG3706	GGDEF domain
NRK98_02035	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NRK98_02045	COG0114	fumarate hydratase activity
NRK98_02115	COG0312	modulator of DNA gyrase
NRK98_02120	COG0312	modulator of DNA gyrase
NRK98_02130	COG4974	Belongs to the 'phage' integrase family
NRK98_02140	COG1970	mechanosensitive ion channel activity
NRK98_02150	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NRK98_02155	COG0789	Transcriptional regulator
NRK98_02175	COG3545	Serine hydrolase
NRK98_02180	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NRK98_02185	COG0321	lipoyl(octanoyl) transferase activity
NRK98_02190	COG2921	Belongs to the UPF0250 family
NRK98_02195	COG1686	Belongs to the peptidase S11 family
NRK98_02200	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NRK98_02205	COG2951	lytic endotransglycosylase activity
NRK98_02210	COG0772	Belongs to the SEDS family
NRK98_02215	COG0768	penicillin binding
NRK98_02220	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NRK98_02225	COG0799	negative regulation of ribosome biogenesis
NRK98_02230	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NRK98_02245	COG0495	leucyl-tRNA aminoacylation
NRK98_02250	COG2888	peptidyl-tyrosine sulfation
NRK98_02255	COG0815	Transfers the fatty acyl group on membrane lipoproteins
NRK98_02260	COG4535	Mg2 and Co2 transporter CorC
NRK98_02265	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NRK98_02270	COG1702	phosphate starvation-inducible protein PhoH
NRK98_02275	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NRK98_02280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NRK98_02285	COG1335	isochorismatase
NRK98_02295	COG3706	GGDEF domain
NRK98_02310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRK98_02330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NRK98_02340	COG3647	Membrane
NRK98_02345	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NRK98_02355	COG0516	GMP reductase activity
NRK98_02365	COG0642	Histidine kinase
NRK98_02400	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NRK98_02405	COG3214	Protein conserved in bacteria
NRK98_02430	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
NRK98_02435	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NRK98_02440	COG1053	succinate dehydrogenase
NRK98_02450	COG0584	glycerophosphoryl diester phosphodiesterase
NRK98_02455	COG3264	Mechanosensitive ion channel
NRK98_02455	COG1511	domain protein
NRK98_02465	COG0739	heme binding
NRK98_02480	COG0583	DNA-binding transcription factor activity
NRK98_02500	COG0583	DNA-binding transcription factor activity
NRK98_02505	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NRK98_02535	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NRK98_02540	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NRK98_02550	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NRK98_02555	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NRK98_02565	COG0180	Tryptophanyl-tRNA synthetase
NRK98_02580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NRK98_02590	COG1012	belongs to the aldehyde dehydrogenase family
NRK98_02625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRK98_02635	COG0488	(ABC) transporter
NRK98_02645	COG0366	Alpha amylase catalytic
NRK98_02665	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
NRK98_02675	COG0490	domain, Protein
NRK98_02675	COG0471	metal ion transport
NRK98_02715	COG0012	GTP binding
NRK98_02720	COG0193	aminoacyl-tRNA hydrolase activity
NRK98_02725	COG0737	Belongs to the 5'-nucleotidase family
NRK98_02730	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NRK98_02740	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NRK98_02745	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NRK98_02750	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NRK98_02755	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NRK98_02760	COG2890	protein-(glutamine-N5) methyltransferase activity
NRK98_02770	COG2912	Transglutaminase-like superfamily
NRK98_02775	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NRK98_02780	COG1301	dicarboxylic acid transport
NRK98_02790	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NRK98_02805	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NRK98_02810	COG1115	amino acid carrier protein
NRK98_02825	COG0714	Associated with various cellular activities
NRK98_02835	COG3104	oligopeptide transport
NRK98_02840	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NRK98_02845	COG1678	Uncharacterized ACR, COG1678
NRK98_02855	COG0189	ligase activity
NRK98_02860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NRK98_02870	COG3091	SprT-like family
NRK98_02880	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NRK98_02895	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NRK98_02900	COG0739	heme binding
NRK98_02905	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NRK98_02910	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
NRK98_02910	COG3408	Glycogen debranching enzyme
NRK98_02920	COG1881	PFAM PEBP family protein
NRK98_02925	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NRK98_02930	COG0583	DNA-binding transcription factor activity
NRK98_02940	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NRK98_02950	COG0583	DNA-binding transcription factor activity
NRK98_02955	COG1028	Short-chain dehydrogenase reductase Sdr
NRK98_02960	COG0616	signal peptide processing
NRK98_02965	COG3724	N-succinylarginine dihydrolase activity
NRK98_02985	COG0840	transmembrane signaling receptor activity
NRK98_02995	COG2971	BadF BadG BcrA BcrD
NRK98_03005	COG4608	Belongs to the ABC transporter superfamily
NRK98_03010	COG0444	Belongs to the ABC transporter superfamily
NRK98_03015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRK98_03020	COG0601	transmembrane transport
NRK98_03025	COG4166	transmembrane transport
NRK98_03030	COG0784	Response regulator, receiver
NRK98_03030	COG2205	protein histidine kinase activity
NRK98_03070	COG3220	belongs to the UPF0276 family
NRK98_03100	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NRK98_03105	COG1289	transmembrane transporter activity
NRK98_03110	COG0303	'Molybdopterin
NRK98_03115	COG0746	molybdenum cofactor guanylyltransferase activity
NRK98_03125	COG4662	Binding-protein-dependent transport system inner membrane component
NRK98_03140	COG3852	Histidine kinase
NRK98_03145	COG1910	domain protein
NRK98_03150	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NRK98_03185	COG3383	formate dehydrogenase (NAD+) activity
NRK98_03185	COG3383	formate dehydrogenase (NAD+) activity
NRK98_03190	COG0437	4 iron, 4 sulfur cluster binding
NRK98_03200	COG0281	malic enzyme
NRK98_03220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRK98_03235	COG2706	6-phosphogluconolactonase activity
NRK98_03245	COG3264	Mechanosensitive ion channel
NRK98_03245	COG1196	nuclear chromosome segregation
NRK98_03250	COG0469	pyruvate kinase activity
NRK98_03265	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NRK98_03265	COG4651	solute:proton antiporter activity
NRK98_03275	COG2974	May be involved in recombination
NRK98_03285	COG0420	3'-5' exonuclease activity
NRK98_03295	COG3038	cytochrome b561
NRK98_03305	COG2190	(PTS) system
NRK98_03310	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NRK98_03315	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRK98_03320	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NRK98_03325	COG0542	response to heat
NRK98_03340	COG3437	response regulator, receiver
NRK98_03340	COG2770	Histidine kinase
NRK98_03345	COG1720	tRNA m6t6A37 methyltransferase activity
NRK98_03365	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NRK98_03370	COG4988	ABC transporter
NRK98_03385	COG0745	RESPONSE REGULATOR receiver
NRK98_03395	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NRK98_03410	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
NRK98_03415	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
NRK98_03425	COG0083	homoserine kinase activity
NRK98_03430	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NRK98_03435	COG4319	ketosteroid isomerase
NRK98_03450	COG0488	(ABC) transporter
NRK98_03465	COG2205	protein histidine kinase activity
NRK98_03465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRK98_03470	COG2203	Gaf domain
NRK98_03470	COG3706	GGDEF domain
NRK98_03470	COG5001	Diguanylate cyclase
NRK98_03470	COG4251	negative regulation of phosphorylation
NRK98_03475	COG0784	Response regulator, receiver
NRK98_03475	COG2205	protein histidine kinase activity
NRK98_03475	COG5002	protein histidine kinase activity
NRK98_03480	COG3384	dioxygenase
NRK98_03490	COG1283	sodium-dependent phosphate transmembrane transporter activity
NRK98_03500	COG0531	amino acid
NRK98_03510	COG0531	amino acid
NRK98_03530	COG1917	Cupin 2, conserved barrel domain protein
NRK98_03530	COG1396	sequence-specific DNA binding
NRK98_03535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRK98_03560	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NRK98_03565	COG2375	cellular response to nickel ion
NRK98_03575	COG0577	efflux transmembrane transporter activity
NRK98_03575	COG1136	(ABC) transporter
NRK98_03580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRK98_03590	COG1227	inorganic diphosphatase activity
NRK98_03595	COG0497	DNA recombination
NRK98_03600	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NRK98_03605	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NRK98_03610	COG0443	Heat shock 70 kDa protein
NRK98_03615	COG0484	heat shock protein binding
NRK98_03645	COG1285	pathogenesis
NRK98_03660	COG0640	Transcriptional regulator
NRK98_03690	COG0095	Lipoate-protein ligase
NRK98_03705	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRK98_03710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRK98_03735	COG0708	Exodeoxyribonuclease III
NRK98_03750	COG0071	Belongs to the small heat shock protein (HSP20) family
NRK98_03755	COG2211	Major facilitator Superfamily
NRK98_03795	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NRK98_03800	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NRK98_03805	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NRK98_03810	COG1845	cytochrome c oxidase, subunit III
NRK98_03815	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NRK98_03820	COG0109	protoheme IX farnesyltransferase activity
NRK98_03825	COG2814	Major facilitator Superfamily
NRK98_03835	COG2175	clavaminate synthase activity
NRK98_03840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NRK98_03845	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NRK98_03850	COG4521	taurine ABC transporter
NRK98_03860	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRK98_03880	COG3550	peptidyl-serine autophosphorylation
NRK98_03885	COG1396	sequence-specific DNA binding
NRK98_03890	COG1988	membrane-bound metal-dependent
NRK98_03905	COG0159	tryptophan synthase activity
NRK98_03910	COG0133	tryptophan synthase activity
NRK98_03915	COG0135	phosphoribosylanthranilate isomerase activity
NRK98_03915	COG0134	indole-3-glycerol-phosphate synthase activity
NRK98_03920	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NRK98_03925	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NRK98_03925	COG0512	Glutamine amidotransferase of anthranilate synthase
NRK98_03930	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NRK98_03940	COG0009	L-threonylcarbamoyladenylate synthase
NRK98_03950	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NRK98_03960	COG1946	Acyl-CoA thioesterase
NRK98_03980	COG1309	transcriptional regulator
NRK98_03985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRK98_03990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRK98_04005	COG1091	dTDP-4-dehydrorhamnose reductase activity
NRK98_04060	COG0438	transferase activity, transferring glycosyl groups
NRK98_04065	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NRK98_04080	COG3132	Protein of unknown function, DUF480
NRK98_04120	COG1278	Cold shock
NRK98_04145	COG4166	transmembrane transport
NRK98_04150	COG0697	spore germination
NRK98_04155	COG1349	DNA-binding transcription factor activity
NRK98_04160	COG1882	Formate acetyltransferase
NRK98_04165	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NRK98_04170	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NRK98_04195	COG4166	transmembrane transport
NRK98_04200	COG0622	Phosphoesterase
NRK98_04215	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
NRK98_04220	COG0835	chemotaxis
NRK98_04220	COG0784	Response regulator, receiver
NRK98_04225	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NRK98_04230	COG1815	bacterial-type flagellum-dependent cell motility
NRK98_04250	COG4787	bacterial-type flagellum-dependent cell motility
NRK98_04260	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
NRK98_04265	COG1706	bacterial-type flagellum-dependent cell motility
NRK98_04270	COG1705	Flagellar rod assembly protein muramidase FlgJ
NRK98_04270	COG3951	Flagellar rod assembly protein muramidase FlgJ
NRK98_04285	COG2239	Acts as a magnesium transporter
NRK98_04295	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NRK98_04300	COG2716	regulation of RNA biosynthetic process
NRK98_04325	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NRK98_04330	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NRK98_04335	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NRK98_04340	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NRK98_04360	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NRK98_04375	COG0590	tRNA wobble adenosine to inosine editing
NRK98_04380	COG0573	inorganic phosphate transmembrane transporter activity
NRK98_04385	COG0581	inorganic phosphate transmembrane transporter activity
NRK98_04390	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NRK98_04395	COG0704	Plays a role in the regulation of phosphate uptake
NRK98_04410	COG1253	flavin adenine dinucleotide binding
NRK98_04425	COG0531	amino acid
NRK98_04450	COG0765	amino acid transport
NRK98_04455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRK98_04460	COG2271	Major facilitator Superfamily
NRK98_04475	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NRK98_04500	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NRK98_04505	COG0477	Major facilitator Superfamily
NRK98_04510	COG0123	including yeast histone deacetylase and acetoin utilization protein
NRK98_04520	COG1199	ATP-dependent helicase activity
NRK98_04535	COG1448	Aminotransferase
NRK98_04540	COG0433	COG0433 Predicted ATPase
NRK98_04555	COG2333	competence protein COMEC
NRK98_04555	COG0658	competence protein
NRK98_04565	COG1663	tetraacyldisaccharide 4'-kinase activity
NRK98_04570	COG2835	tetraacyldisaccharide 4'-kinase activity
NRK98_04575	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NRK98_04580	COG2197	response regulator
NRK98_04585	COG0322	excinuclease ABC activity
NRK98_04740	COG4695	Portal protein
NRK98_04860	COG4974	Belongs to the 'phage' integrase family
NRK98_04905	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
NRK98_04910	COG0437	4 iron, 4 sulfur cluster binding
NRK98_04915	COG3301	Polysulphide reductase, NrfD
NRK98_04920	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NRK98_04930	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NRK98_04935	COG0215	cysteine-tRNA ligase activity
NRK98_04950	COG2199	diguanylate cyclase activity
NRK98_04950	COG2203	Gaf domain
NRK98_04980	COG2119	membrane
NRK98_04985	COG0023	Translation Initiation Factor
NRK98_05025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRK98_05025	COG2205	protein histidine kinase activity
NRK98_05035	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
NRK98_05040	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NRK98_05045	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NRK98_05050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NRK98_05055	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NRK98_05060	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NRK98_05070	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NRK98_05075	COG0505	Belongs to the CarA family
NRK98_05080	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NRK98_05085	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NRK98_05125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRK98_05130	COG0513	Belongs to the DEAD box helicase family
NRK98_05140	COG4104	PAAR repeat-containing protein
NRK98_05155	COG0789	Transcriptional regulator
NRK98_05170	COG0493	'glutamate synthase
NRK98_05175	COG0067	glutamate synthase
NRK98_05175	COG0069	glutamate synthase activity
NRK98_05175	COG0070	glutamate synthase
NRK98_05180	COG1242	4 iron, 4 sulfur cluster binding
NRK98_05250	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NRK98_05255	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NRK98_05255	COG0574	Belongs to the PEP-utilizing enzyme family
NRK98_05295	COG1464	Belongs to the NlpA lipoprotein family
NRK98_05300	COG0671	phosphoesterase, PA-phosphatase related
NRK98_05305	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NRK98_05310	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NRK98_05320	COG0101	tRNA pseudouridine synthase activity
NRK98_05325	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NRK98_05330	COG0285	dihydrofolate synthase activity
NRK98_05335	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
NRK98_05340	COG2920	part of a sulfur-relay system
NRK98_05345	COG1289	transmembrane transporter activity
NRK98_05350	COG0670	Belongs to the BI1 family
NRK98_05370	COG2194	sulfuric ester hydrolase activity
NRK98_05375	COG0392	lysyltransferase activity
NRK98_05375	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NRK98_05385	COG0840	transmembrane signaling receptor activity
NRK98_05390	COG5001	Diguanylate cyclase
NRK98_05395	COG0564	pseudouridine synthase activity
NRK98_05410	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
NRK98_05420	COG0625	glutathione transferase activity
NRK98_05430	COG0367	asparagine synthase
NRK98_05440	COG4651	solute:proton antiporter activity
NRK98_05440	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NRK98_05445	COG0647	UMP catabolic process
NRK98_05450	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NRK98_05455	COG1902	pentaerythritol trinitrate reductase activity
NRK98_05460	COG1253	flavin adenine dinucleotide binding
NRK98_05470	COG0247	lactate metabolic process
NRK98_05470	COG0277	FAD linked oxidase domain protein
NRK98_05480	COG2050	protein possibly involved in aromatic compounds catabolism
NRK98_05490	COG2056	Na+-H+ antiporter family
NRK98_05495	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NRK98_05510	COG0346	lactoylglutathione lyase activity
NRK98_05515	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NRK98_05520	COG4660	Part of a membrane complex involved in electron transport
NRK98_05525	COG4659	FMN binding
NRK98_05530	COG4658	electron transport chain
NRK98_05540	COG2878	Part of a membrane complex involved in electron transport
NRK98_05545	COG4657	Part of a membrane complex involved in electron transport
NRK98_05550	COG0697	spore germination
NRK98_05565	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NRK98_05570	COG1288	antiporter activity
NRK98_05575	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
NRK98_05575	COG3264	Mechanosensitive ion channel
NRK98_05580	COG0436	Aminotransferase
NRK98_05590	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NRK98_05595	COG2027	D-alanyl-D-alanine carboxypeptidase
NRK98_05600	COG1061	Type III restriction enzyme res subunit
NRK98_05605	COG1566	PFAM secretion protein HlyD family protein
NRK98_05615	COG1966	Carbon starvation protein
NRK98_05620	COG3279	Response regulator of the LytR AlgR family
NRK98_05625	COG3275	phosphorelay sensor kinase activity
NRK98_05630	COG2199	diguanylate cyclase activity
NRK98_05630	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NRK98_05635	COG1012	belongs to the aldehyde dehydrogenase family
NRK98_05635	COG1454	alcohol dehydrogenase
NRK98_05645	COG2095	MarC family integral membrane protein
NRK98_05655	COG0601	transmembrane transport
NRK98_05660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRK98_05665	COG0444	Belongs to the ABC transporter superfamily
NRK98_05675	COG0861	Integral membrane protein TerC family
NRK98_05680	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NRK98_05690	COG1301	dicarboxylic acid transport
NRK98_05705	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NRK98_05720	COG0537	adenosine 5'-monophosphoramidase activity
NRK98_05755	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NRK98_05760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NRK98_05775	COG2354	Protein conserved in bacteria
NRK98_05790	COG2233	PERMEase
NRK98_05795	COG3150	esterase
NRK98_05800	COG1252	NADH dehydrogenase
NRK98_05820	COG0393	Putative heavy-metal-binding
NRK98_05830	COG1619	proteins homologs of microcin C7 resistance protein MccF
NRK98_05835	COG1368	sulfuric ester hydrolase activity
NRK98_05845	COG0527	aspartate kinase activity
NRK98_05850	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NRK98_05850	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NRK98_05855	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NRK98_05875	COG0596	Alpha beta hydrolase
NRK98_05880	COG0583	DNA-binding transcription factor activity
NRK98_05885	COG1620	l-lactate permease
NRK98_05895	COG1139	Iron-sulfur cluster binding protein
NRK98_05930	COG0577	efflux transmembrane transporter activity
NRK98_05935	COG1136	(ABC) transporter
NRK98_05955	COG2814	Major facilitator Superfamily
NRK98_05975	COG0672	)-iron permease
NRK98_06015	COG0659	secondary active sulfate transmembrane transporter activity
NRK98_06035	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NRK98_06040	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
NRK98_06045	COG0437	4 iron, 4 sulfur cluster binding
NRK98_06050	COG5557	Pfam Polysulphide reductase, NrfD
NRK98_06055	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
NRK98_06060	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NRK98_06065	COG1773	rubredoxin
NRK98_06075	COG0601	transmembrane transport
NRK98_06080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRK98_06090	COG1124	(ABC) transporter
NRK98_06095	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NRK98_06105	COG0375	protein maturation
NRK98_06110	COG0309	Hydrogenase expression formation protein (HypE)
NRK98_06120	COG0298	carbon dioxide binding
NRK98_06125	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
NRK98_06135	COG1921	L-seryl-tRNASec selenium transferase activity
NRK98_06145	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NRK98_06155	COG3260	NADH ubiquinone oxidoreductase 20
NRK98_06160	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRK98_06165	COG3261	NADH dehydrogenase
NRK98_06165	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
NRK98_06170	COG0650	Formate hydrogenlyase subunit 4
NRK98_06175	COG0651	ATP synthesis coupled electron transport
NRK98_06180	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
NRK98_06185	COG3158	transport of potassium into the cell
NRK98_06195	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
NRK98_06220	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NRK98_06225	COG0326	Molecular chaperone. Has ATPase activity
NRK98_06230	COG0563	adenylate kinase activity
NRK98_06235	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NRK98_06240	COG3788	relative of glutathione S-transferase, MAPEG superfamily
NRK98_06245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRK98_06260	COG5001	Diguanylate cyclase
NRK98_06260	COG3300	MHYT domain
NRK98_06265	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NRK98_06290	COG1021	2,3-dihydroxybenzoate-AMP ligase
NRK98_06295	COG3433	isochorismatase activity
NRK98_06295	COG1535	isochorismatase
NRK98_06300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NRK98_06305	COG1028	Short-chain dehydrogenase reductase Sdr
NRK98_06315	COG0300	oxidoreductase activity
NRK98_06315	COG3321	synthase
NRK98_06315	COG0318	PFAM AMP-dependent synthetase and ligase
NRK98_06315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NRK98_06315	COG1028	Short-chain dehydrogenase reductase Sdr
NRK98_06320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NRK98_06330	COG1120	ATPase activity
NRK98_06335	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRK98_06340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRK98_06345	COG4771	TonB-dependent receptor
NRK98_06385	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NRK98_06390	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NRK98_06395	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NRK98_06410	COG1570	exodeoxyribonuclease VII activity
NRK98_06415	COG0697	spore germination
NRK98_06435	COG3158	transport of potassium into the cell
NRK98_06440	COG0516	GMP reductase activity
NRK98_06440	COG0517	IMP dehydrogenase activity
NRK98_06445	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NRK98_06445	COG0519	Catalyzes the synthesis of GMP from XMP
NRK98_06450	COG0582	viral genome integration into host DNA
NRK98_06485	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NRK98_06545	COG2062	phosphohistidine phosphatase, SixA
NRK98_06555	COG0697	spore germination
NRK98_06560	COG4166	transmembrane transport
NRK98_06565	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
NRK98_06570	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NRK98_06580	COG4591	ABC-type transport system involved in lipoprotein release permease component
NRK98_06585	COG1136	(ABC) transporter
NRK98_06590	COG4591	ABC-type transport system involved in lipoprotein release permease component
NRK98_06595	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
NRK98_06605	COG0544	peptidyl-prolyl cis-trans isomerase activity
NRK98_06610	COG0740	serine-type endopeptidase activity
NRK98_06615	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NRK98_06620	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NRK98_06625	COG0776	regulation of translation
NRK98_06630	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NRK98_06635	COG0488	(ABC) transporter
NRK98_06640	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NRK98_06645	COG3162	membrane
NRK98_06660	COG1024	Enoyl-CoA hydratase
NRK98_06665	COG1115	amino acid carrier protein
NRK98_06680	COG1584	GPR1 FUN34 yaaH family protein
NRK98_06715	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NRK98_06720	COG1960	acyl-CoA dehydrogenase activity
NRK98_06730	COG1960	acyl-CoA dehydrogenase activity
NRK98_06735	COG1024	Enoyl-CoA hydratase
NRK98_06740	COG1024	Enoyl-CoA hydratase
NRK98_06750	COG1028	Short-chain dehydrogenase reductase Sdr
NRK98_06760	COG0730	response to heat
NRK98_06775	COG1073	alpha beta
NRK98_06780	COG1506	peptidase
NRK98_06780	COG0823	Involved in the tonB-independent uptake of proteins
NRK98_06785	COG0702	epimerase
NRK98_06810	COG0583	DNA-binding transcription factor activity
NRK98_06815	COG2723	6-phospho-beta-galactosidase activity
NRK98_06820	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NRK98_06830	COG0583	DNA-binding transcription factor activity
NRK98_06835	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NRK98_06840	COG0673	inositol 2-dehydrogenase activity
NRK98_06845	COG0583	DNA-binding transcription factor activity
NRK98_06855	COG1560	Kdo2-lipid A biosynthetic process
NRK98_06860	COG1560	Kdo2-lipid A biosynthetic process
NRK98_06875	COG2199	diguanylate cyclase activity
NRK98_06875	COG2203	Gaf domain
NRK98_06885	COG0417	DNA replication proofreading
NRK98_06915	COG0534	Mate efflux family protein
NRK98_06925	COG0307	riboflavin synthase, alpha
NRK98_06935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRK98_06940	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NRK98_06945	COG0697	spore germination
NRK98_06950	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NRK98_06995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NRK98_07000	COG3099	Belongs to the UPF0263 family
NRK98_07005	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NRK98_07010	COG2894	cell division
NRK98_07015	COG0850	regulation of cytokinetic process
NRK98_07020	COG3100	YcgL domain-containing protein
NRK98_07025	COG2951	lytic endotransglycosylase activity
NRK98_07030	COG1760	l-serine dehydratase
NRK98_07035	COG1760	l-serine dehydratase
NRK98_07040	COG3123	guanosine phosphorylase activity
NRK98_07060	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
NRK98_07065	COG2067	long-chain fatty acid transport protein
NRK98_07080	COG1595	DNA-templated transcription, initiation
NRK98_07110	COG0714	Associated with various cellular activities
NRK98_07115	COG0183	Belongs to the thiolase family
NRK98_07120	COG1024	Enoyl-CoA hydratase
NRK98_07120	COG1250	3-hydroxyacyl-CoA dehydrogenase
NRK98_07140	COG3829	transcription factor binding
NRK98_07145	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NRK98_07150	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NRK98_07155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NRK98_07165	COG0549	Belongs to the carbamate kinase family
NRK98_07170	COG0697	spore germination
NRK98_07175	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NRK98_07175	COG3608	succinylglutamate desuccinylase aspartoacylase
NRK98_07180	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NRK98_07185	COG2068	MobA-Related Protein
NRK98_07190	COG0493	'glutamate synthase
NRK98_07190	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NRK98_07195	COG0402	S-adenosylhomocysteine deaminase activity
NRK98_07200	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NRK98_07205	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NRK98_07205	COG2080	2 iron, 2 sulfur cluster binding
NRK98_07210	COG2233	PERMEase
NRK98_07215	COG0402	S-adenosylhomocysteine deaminase activity
NRK98_07220	COG2252	PERMEase
NRK98_07225	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NRK98_07230	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NRK98_07235	COG2080	2 iron, 2 sulfur cluster binding
NRK98_07245	COG3134	Outer membrane lipoprotein
NRK98_07255	COG1288	antiporter activity
NRK98_07260	COG0318	PFAM AMP-dependent synthetase and ligase
NRK98_07270	COG0140	phosphoribosyl-ATP diphosphatase activity
NRK98_07270	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NRK98_07275	COG0107	imidazoleglycerol-phosphate synthase activity
NRK98_07280	COG0784	Response regulator, receiver
NRK98_07280	COG2198	Histidine kinase
NRK98_07280	COG2205	protein histidine kinase activity
NRK98_07285	COG2199	diguanylate cyclase activity
NRK98_07290	COG3437	response regulator, receiver
NRK98_07295	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NRK98_07300	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NRK98_07305	COG0131	Imidazoleglycerol-phosphate dehydratase
NRK98_07305	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NRK98_07310	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NRK98_07315	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NRK98_07320	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NRK98_07330	COG1199	ATP-dependent helicase activity
NRK98_07335	COG1214	PFAM Peptidase M22, glycoprotease
NRK98_07345	COG2267	carboxylic ester hydrolase activity
NRK98_07350	COG0318	PFAM AMP-dependent synthetase and ligase
NRK98_07355	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
NRK98_07370	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NRK98_07375	COG2832	Protein of unknown function (DUF454)
NRK98_07380	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NRK98_07385	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NRK98_07390	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NRK98_07395	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NRK98_07405	COG3314	Sporulation integral membrane protein YlbJ
NRK98_07415	COG0517	IMP dehydrogenase activity
NRK98_07415	COG0617	tRNA 3'-terminal CCA addition
NRK98_07415	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NRK98_07420	COG1643	Atp-dependent helicase
NRK98_07430	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NRK98_07440	COG3437	response regulator, receiver
NRK98_07445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRK98_07450	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
NRK98_07455	COG0709	Synthesizes selenophosphate from selenide and ATP
NRK98_07475	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NRK98_07485	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NRK98_07490	COG0840	transmembrane signaling receptor activity
NRK98_07495	COG1254	Belongs to the acylphosphatase family
NRK98_07500	COG0625	glutathione transferase activity
NRK98_07505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRK98_07505	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRK98_07510	COG0489	protein tyrosine kinase activity
NRK98_07515	COG0572	uridine kinase
NRK98_07520	COG0717	Belongs to the dCTP deaminase family
NRK98_07525	COG0306	phosphate transporter
NRK98_07530	COG1530	ribonuclease E activity
NRK98_07540	COG0546	phosphoglycolate phosphatase activity
NRK98_07545	COG0424	maF-like protein
NRK98_07555	COG1399	metal-binding, possibly nucleic acid-binding protein
NRK98_07560	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NRK98_07565	COG0416	fatty acid biosynthetic process
NRK98_07570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NRK98_07580	COG1028	Short-chain dehydrogenase reductase Sdr
NRK98_07585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NRK98_07595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NRK98_07600	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NRK98_07605	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NRK98_07610	COG0470	DNA polymerase III
NRK98_07615	COG0084	hydrolase, TatD family'
NRK98_07630	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NRK98_07630	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
NRK98_07635	COG3008	intermembrane lipid transfer
NRK98_07640	COG2995	paraquat-inducible protein a
NRK98_07650	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NRK98_07655	COG0372	Belongs to the citrate synthase family
NRK98_07675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NRK98_07700	COG4221	oxidoreductase activity
NRK98_07710	COG3141	response to X-ray
NRK98_07720	COG1067	ATP-dependent peptidase activity
NRK98_07725	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NRK98_07740	COG0488	(ABC) transporter
NRK98_07750	COG0116	Belongs to the methyltransferase superfamily
NRK98_07750	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NRK98_07760	COG0167	dihydroorotate dehydrogenase activity
NRK98_07765	COG2902	Dehydrogenase
NRK98_07775	COG0308	aminopeptidase N
NRK98_07785	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
NRK98_07790	COG1956	GAF domain-containing protein
NRK98_07800	COG3278	Belongs to the heme-copper respiratory oxidase family
NRK98_07815	COG2010	Cytochrome c
NRK98_07840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NRK98_07845	COG0589	response to stress
NRK98_07850	COG0037	tRNA processing
NRK98_07865	COG0625	glutathione transferase activity
NRK98_07870	COG1869	D-ribose catabolic process
NRK98_07875	COG1129	ABC transporter
NRK98_07880	COG1172	Belongs to the binding-protein-dependent transport system permease family
NRK98_07885	COG1879	ABC-type sugar transport system periplasmic component
NRK98_07890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRK98_07895	COG1609	Transcriptional regulator
NRK98_07900	COG2199	diguanylate cyclase activity
NRK98_07925	COG0784	Response regulator, receiver
NRK98_07925	COG2205	protein histidine kinase activity
NRK98_07930	COG0776	regulation of translation
NRK98_07935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRK98_07935	COG0072	phenylalanine-tRNA ligase activity
NRK98_07940	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NRK98_07945	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NRK98_07950	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NRK98_07955	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NRK98_07960	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NRK98_07985	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NRK98_07995	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NRK98_08000	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NRK98_08005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NRK98_08010	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
NRK98_08015	COG3313	Fe-S protein
NRK98_08020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRK98_08020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRK98_08020	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
NRK98_08025	COG1105	Belongs to the carbohydrate kinase PfkB family
NRK98_08030	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRK98_08030	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRK98_08035	COG1609	Transcriptional regulator
NRK98_08040	COG0814	amino acid
NRK98_08055	COG0513	Belongs to the DEAD box helicase family
NRK98_08065	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NRK98_08070	COG2890	protein-(glutamine-N5) methyltransferase activity
NRK98_08075	COG2840	Smr protein MutS2
NRK98_08085	COG3706	GGDEF domain
NRK98_08115	COG2824	Alkylphosphonate utilization operon protein PhnA
NRK98_08130	COG0384	phenazine biosynthesis protein PhzF
NRK98_08155	COG0242	peptide deformylase activity
NRK98_08180	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NRK98_08185	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
NRK98_08190	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
NRK98_08200	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NRK98_08205	COG1434	Gram-negative-bacterium-type cell wall biogenesis
NRK98_08215	COG0205	6-phosphofructokinase activity
NRK98_08220	COG1473	amidohydrolase
NRK98_08225	COG1011	Hydrolase
NRK98_08230	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NRK98_08260	COG3593	DNA synthesis involved in DNA repair
NRK98_08275	COG0583	DNA-binding transcription factor activity
NRK98_08280	COG0730	response to heat
NRK98_08285	COG3148	PFAM DTW domain containing protein
NRK98_08295	COG1181	Belongs to the D-alanine--D-alanine ligase family
NRK98_08305	COG0386	Belongs to the glutathione peroxidase family
NRK98_08310	COG0513	Belongs to the DEAD box helicase family
NRK98_08350	COG2329	Antibiotic biosynthesis monooxygenase
NRK98_08355	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NRK98_08375	COG3243	poly(R)-hydroxyalkanoic acid synthase
NRK98_08385	COG2501	S4 domain
NRK98_08400	COG1132	(ABC) transporter
NRK98_08405	COG1132	(ABC) transporter
NRK98_08415	COG3118	belongs to the thioredoxin family
NRK98_08420	COG0471	metal ion transport
NRK98_08425	COG0058	SHG alpha-glucan phosphorylase activity
NRK98_08460	COG0814	amino acid
NRK98_08465	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NRK98_08470	COG0514	ATP-dependent DNA helicase (RecQ)
NRK98_08475	COG2766	serine protein kinase
NRK98_08480	COG2718	Belongs to the UPF0229 family
NRK98_08485	COG2719	SpoVR family
NRK98_08490	COG2186	Transcriptional regulator
NRK98_08495	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NRK98_08500	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NRK98_08505	COG0586	Pfam SNARE associated Golgi protein
NRK98_08515	COG0556	nucleotide-excision repair
NRK98_08525	COG0569	domain protein
NRK98_08525	COG2985	domain, Protein
NRK98_08530	COG0739	heme binding
NRK98_08530	COG1196	nuclear chromosome segregation
NRK98_08530	COG0741	lytic transglycosylase activity
NRK98_08535	COG3181	Tripartite tricarboxylate transporter family receptor
NRK98_08550	COG4565	transcriptional regulatory protein
NRK98_08555	COG3290	protein histidine kinase activity
NRK98_08560	COG1940	carbohydrate kinase activity
NRK98_08560	COG1846	Transcriptional regulator
NRK98_08565	COG0840	transmembrane signaling receptor activity
NRK98_08570	COG3012	SEC-C Motif Domain Protein
NRK98_08575	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NRK98_08580	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
NRK98_08585	COG0247	lactate metabolic process
NRK98_08595	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
NRK98_08600	COG0437	4 iron, 4 sulfur cluster binding
NRK98_08605	COG3301	Polysulphide reductase, NrfD
NRK98_08610	COG1138	Cytochrome C-type biogenesis protein
NRK98_08620	COG3088	subunit of a heme lyase
NRK98_08620	COG4235	cytochrome complex assembly
NRK98_08635	COG3033	Beta-eliminating lyase
NRK98_08645	COG3046	protein related to deoxyribodipyrimidine photolyase
NRK98_08650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRK98_08685	COG0516	GMP reductase activity
NRK98_08685	COG0517	IMP dehydrogenase activity
NRK98_08700	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NRK98_08715	COG4774	siderophore transport
NRK98_08720	COG4977	sequence-specific DNA binding
NRK98_08730	COG0583	DNA-binding transcription factor activity
NRK98_08735	COG2910	NAD(P)H-binding
NRK98_08750	COG0612	Peptidase, M16
NRK98_08755	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NRK98_08765	COG1944	ATP diphosphatase activity
NRK98_08770	COG2116	formate transmembrane transporter activity
NRK98_08775	COG1882	Formate acetyltransferase
NRK98_08780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRK98_08785	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NRK98_08790	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NRK98_08800	COG1840	ABC-type Fe3 transport system, periplasmic component
NRK98_08805	COG3842	ATPase activity
NRK98_08815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRK98_08820	COG2983	Belongs to the UPF0260 family
NRK98_08830	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NRK98_08835	COG0045	succinate-CoA ligase (ADP-forming) activity
NRK98_08840	COG0508	dehydrogenase complex catalyzes the overall conversion of
NRK98_08845	COG0567	Dehydrogenase, E1 component
NRK98_08860	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NRK98_08885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NRK98_08890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRK98_08890	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NRK98_08900	COG3069	C4-dicarboxylate transmembrane transporter activity
NRK98_08915	COG1451	nucleotide metabolic process
NRK98_08930	COG0254	rRNA binding
NRK98_08935	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NRK98_08945	COG0583	DNA-binding transcription factor activity
NRK98_09020	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NRK98_09055	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NRK98_09070	COG2925	Exonuclease
NRK98_09080	COG3345	alpha-galactosidase
NRK98_09085	COG1380	Effector of murein hydrolase LrgA
NRK98_09090	COG1346	cytolysis
NRK98_09095	COG0295	cytidine deaminase activity
NRK98_09100	COG1022	Amp-dependent synthetase and ligase
NRK98_09115	COG0861	Integral membrane protein TerC family
NRK98_09120	COG2885	chlorophyll binding
NRK98_09140	COG2154	pterin-4-alpha-carbinolamine dehydratase
NRK98_09150	COG3768	UPF0283 membrane protein
NRK98_09155	COG3106	COG3106 Predicted ATPase
NRK98_09170	COG1842	Phage shock protein A
NRK98_09175	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NRK98_09185	COG4168	peptide transport system, permease
NRK98_09190	COG4171	peptide transport system, permease
NRK98_09200	COG4172	Belongs to the ABC transporter superfamily
NRK98_09210	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NRK98_09215	COG1286	toxin biosynthetic process
NRK98_09220	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NRK98_09225	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NRK98_09230	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NRK98_09235	COG0531	amino acid
NRK98_09235	COG1674	ftsk spoiiie
NRK98_09245	COG0492	ferredoxin-NADP+ reductase activity
NRK98_09250	COG3706	GGDEF domain
NRK98_09255	COG3134	Outer membrane lipoprotein
NRK98_09260	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NRK98_09265	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NRK98_09270	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NRK98_09275	COG0542	response to heat
NRK98_09280	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NRK98_09285	COG1278	Cold shock
NRK98_09290	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NRK98_09390	COG3829	transcription factor binding
NRK98_09465	COG3501	Rhs element vgr protein
NRK98_09525	COG1435	thymidine kinase activity
NRK98_09530	COG1757	Na H antiporter
NRK98_09535	COG2916	Histone family protein nucleoid-structuring protein H-NS
NRK98_09540	COG2096	Adenosyltransferase
NRK98_09545	COG3530	Putative quorum-sensing-regulated virulence factor
NRK98_09550	COG0602	queuosine metabolic process
NRK98_09555	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NRK98_09575	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NRK98_09585	COG0776	regulation of translation
NRK98_09590	COG0539	negative regulation of cytoplasmic translation
NRK98_09595	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NRK98_09600	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NRK98_09610	COG0583	DNA-binding transcription factor activity
NRK98_09630	COG0778	Nitroreductase
NRK98_09635	COG3300	MHYT domain
NRK98_09635	COG5001	Diguanylate cyclase
NRK98_09645	COG0583	DNA-binding transcription factor activity
NRK98_09650	COG3437	response regulator, receiver
NRK98_09675	COG4989	oxidoreductase activity
NRK98_09680	COG0724	RNA recognition motif
NRK98_09700	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NRK98_09720	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NRK98_09725	COG1360	Flagellar Motor Protein
NRK98_09730	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRK98_09735	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRK98_09740	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRK98_09740	COG0649	NAD binding
NRK98_09755	COG1034	ATP synthesis coupled electron transport
NRK98_09760	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NRK98_09765	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRK98_09770	COG0839	Belongs to the complex I subunit 6 family
NRK98_09775	COG0713	ATP synthesis coupled electron transport
NRK98_09785	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRK98_09790	COG1007	ATP synthesis coupled electron transport
NRK98_09805	COG2199	diguanylate cyclase activity
NRK98_09805	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NRK98_09810	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NRK98_09810	COG0047	phosphoribosylformylglycinamidine synthase activity
NRK98_09815	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NRK98_09820	COG1645	bacterial-type flagellum-dependent swarming motility
NRK98_09825	COG1160	GTP binding
NRK98_09830	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NRK98_09835	COG2976	Protein conserved in bacteria
NRK98_09840	COG0124	histidyl-tRNA synthetase
NRK98_09845	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NRK98_09860	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NRK98_09865	COG0105	UTP biosynthetic process
NRK98_09870	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NRK98_09880	COG0633	Ferredoxin
NRK98_09885	COG0443	Heat shock 70 kDa protein
NRK98_09890	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NRK98_09900	COG0822	iron-sulfur transferase activity
NRK98_09905	COG1104	cysteine desulfurase activity
NRK98_09925	COG3154	lipid carrier protein
NRK98_09930	COG0826	peptidase U32
NRK98_09935	COG0826	peptidase U32
NRK98_09950	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NRK98_09955	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NRK98_09960	COG1862	Preprotein translocase
NRK98_09965	COG0343	queuine tRNA-ribosyltransferase activity
NRK98_09970	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NRK98_09975	COG0517	IMP dehydrogenase activity
NRK98_09985	COG3634	alkyl hydroperoxide reductase activity
NRK98_09990	COG0477	Major facilitator Superfamily
NRK98_09995	COG3852	Histidine kinase
NRK98_10010	COG3119	arylsulfatase activity
NRK98_10015	COG0641	radical SAM
NRK98_10030	COG5642	Protein of unknown function (DUF2384)
NRK98_10065	COG2801	Transposase and inactivated derivatives
NRK98_10085	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NRK98_10085	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NRK98_10090	COG0509	glycine decarboxylation via glycine cleavage system
NRK98_10095	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NRK98_10100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NRK98_10105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NRK98_10125	COG2814	Major facilitator Superfamily
NRK98_10130	COG0625	glutathione transferase activity
NRK98_10140	COG0483	inositol monophosphate 1-phosphatase activity
NRK98_10160	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NRK98_10170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NRK98_10200	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NRK98_10220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRK98_10220	COG0301	tRNA thio-modification
NRK98_10230	COG4953	penicillin-binding protein 1C
NRK98_10235	COG2373	Large extracellular alpha-helical protein
NRK98_10240	COG0446	pyridine nucleotide-disulphide oxidoreductase
NRK98_10250	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NRK98_10285	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NRK98_10325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRK98_10335	COG2431	L-lysine efflux transmembrane transporter activity
NRK98_10340	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NRK98_10365	COG1393	Belongs to the ArsC family
NRK98_10375	COG4783	chaperone-mediated protein folding
NRK98_10380	COG0425	Belongs to the sulfur carrier protein TusA family
NRK98_10395	COG0596	Alpha beta hydrolase
NRK98_10405	COG3842	ATPase activity
NRK98_10410	COG3833	ABC-type maltose transport systems, permease component
NRK98_10415	COG1175	transmembrane transport
NRK98_10425	COG3081	Nucleoid-associated protein
NRK98_10430	COG3082	Protein of unknown function (DUF1414)
NRK98_10435	COG3083	sulfuric ester hydrolase activity
NRK98_10440	COG4771	TonB-dependent receptor
NRK98_10445	COG1770	oligopeptidase
NRK98_10465	COG4574	serine-type endopeptidase inhibitor activity
NRK98_10470	COG3085	chromosome segregation
NRK98_10475	COG0583	DNA-binding transcription factor activity
NRK98_10480	COG1605	Chorismate mutase
NRK98_10480	COG0287	Prephenate dehydrogenase
NRK98_10485	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NRK98_10490	COG0584	glycerophosphoryl diester phosphodiesterase
NRK98_10505	COG1349	DNA-binding transcription factor activity
NRK98_10510	COG2271	Major facilitator Superfamily
NRK98_10515	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NRK98_10520	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NRK98_10525	COG0840	transmembrane signaling receptor activity
NRK98_10535	COG0583	DNA-binding transcription factor activity
NRK98_10570	COG0656	L-ascorbic acid biosynthetic process
NRK98_10575	COG2814	Major facilitator Superfamily
NRK98_10590	COG3220	belongs to the UPF0276 family
NRK98_10610	COG1294	oxidase, subunit
NRK98_10620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRK98_10630	COG2979	Protein of unknown function (DUF533)
NRK98_10660	COG2271	Major facilitator Superfamily
NRK98_10665	COG0583	DNA-binding transcription factor activity
NRK98_10675	COG2807	transmembrane transport
NRK98_10685	COG1187	pseudouridine synthase activity
NRK98_10700	COG1403	HNH endonuclease
NRK98_10710	COG2964	Protein conserved in bacteria
NRK98_10715	COG3681	Belongs to the UPF0597 family
NRK98_10725	COG0814	amino acid
NRK98_10730	COG0840	transmembrane signaling receptor activity
NRK98_10745	COG0583	DNA-binding transcription factor activity
NRK98_10750	COG2015	COG2015, Alkyl sulfatase and related hydrolases
NRK98_10760	COG1166	arginine decarboxylase activity
NRK98_10770	COG2195	Cleaves the N-terminal amino acid of tripeptides
NRK98_10800	COG0583	DNA-binding transcription factor activity
NRK98_10810	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NRK98_10815	COG0840	transmembrane signaling receptor activity
NRK98_10820	COG0302	gtp cyclohydrolase
NRK98_10830	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NRK98_10835	COG2267	carboxylic ester hydrolase activity
NRK98_10840	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NRK98_10855	COG0314	molybdopterin synthase activity
NRK98_10860	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NRK98_10865	COG0315	cyclic pyranopterin monophosphate synthase activity
NRK98_10870	COG0521	Mo-molybdopterin cofactor biosynthetic process
NRK98_10875	COG3005	denitrification pathway
NRK98_10885	COG0348	domain, Protein
NRK98_10890	COG0437	4 iron, 4 sulfur cluster binding
NRK98_10895	COG0243	molybdopterin cofactor binding
NRK98_10905	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
NRK98_10905	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NRK98_10910	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NRK98_10915	COG3850	Histidine kinase
NRK98_10920	COG2197	response regulator
NRK98_10950	COG0121	glutamine amidotransferase
NRK98_10955	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NRK98_10960	COG1960	acyl-CoA dehydrogenase activity
NRK98_10965	COG0784	Response regulator, receiver
NRK98_10965	COG3437	response regulator, receiver
NRK98_10975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NRK98_10980	COG0328	RNA-DNA hybrid ribonuclease activity
NRK98_10985	COG2226	methyltransferase
NRK98_10990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRK98_11000	COG1388	LysM domain
NRK98_11000	COG0741	lytic transglycosylase activity
NRK98_11005	COG3021	interspecies interaction between organisms
NRK98_11015	COG1607	acyl-coa hydrolase
NRK98_11030	COG0741	lytic transglycosylase activity
NRK98_11040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NRK98_11065	COG0729	surface antigen
NRK98_11075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NRK98_11080	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NRK98_11090	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NRK98_11100	COG4134	Bacterial extracellular solute-binding protein
NRK98_11110	COG4136	ATPase activity
NRK98_11115	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NRK98_11120	COG2951	lytic endotransglycosylase activity
NRK98_11135	COG1846	Transcriptional regulator
NRK98_11145	COG0033	Phosphoglucomutase
NRK98_11150	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
NRK98_11155	COG0596	Alpha beta hydrolase
NRK98_11170	COG0716	FMN binding
NRK98_11180	COG0735	belongs to the Fur family
NRK98_11185	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NRK98_11195	COG2190	(PTS) system
NRK98_11195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRK98_11195	COG1263	PTS System
NRK98_11200	COG0363	glucosamine-6-phosphate deaminase activity
NRK98_11205	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NRK98_11210	COG1940	carbohydrate kinase activity
NRK98_11210	COG1846	Transcriptional regulator
NRK98_11215	COG2194	sulfuric ester hydrolase activity
NRK98_11220	COG0217	transcriptional regulatory protein
NRK98_11225	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NRK98_11230	COG1801	Protein of unknown function DUF72
NRK98_11235	COG4106	trans-aconitate 2-methyltransferase activity
NRK98_11240	COG0500	methyltransferase
NRK98_11260	COG0450	alkyl hydroperoxide reductase
NRK98_11265	COG0583	DNA-binding transcription factor activity
NRK98_11275	COG0791	NLP P60 protein
NRK98_11290	COG1309	transcriptional regulator
NRK98_11330	COG0534	Mate efflux family protein
NRK98_11340	COG2841	Protein conserved in bacteria
NRK98_11345	COG1917	Cupin 2, conserved barrel domain protein
NRK98_11345	COG2169	Transcriptional regulator
NRK98_11350	COG2366	antibiotic biosynthetic process
NRK98_11355	COG1013	pyruvate-flavodoxin oxidoreductase activity
NRK98_11355	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NRK98_11355	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NRK98_11355	COG0674	pyruvate-flavodoxin oxidoreductase activity
NRK98_11365	COG0633	Ferredoxin
NRK98_11365	COG3217	Mosc domain protein beta barrel domain protein
NRK98_11365	COG0633	Ferredoxin
NRK98_11365	COG3217	Mosc domain protein beta barrel domain protein
NRK98_11375	COG0501	Belongs to the peptidase M48B family
NRK98_11380	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NRK98_11385	COG1073	alpha beta
NRK98_11385	COG2226	methyltransferase
NRK98_11390	COG0156	8-amino-7-oxononanoate synthase activity
NRK98_11395	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NRK98_11415	COG0017	Asparaginyl-tRNA synthetase
NRK98_11420	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NRK98_11435	COG3069	C4-dicarboxylate transmembrane transporter activity
NRK98_11445	COG0583	DNA-binding transcription factor activity
NRK98_11450	COG1393	Belongs to the ArsC family
NRK98_11455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NRK98_11460	COG1876	peptidase activity
NRK98_11470	COG3263	regulation of cellular component size
NRK98_11490	COG1280	lysine exporter protein (LysE YggA)
NRK98_11520	COG0564	pseudouridine synthase activity
NRK98_11530	COG1454	alcohol dehydrogenase
NRK98_11535	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NRK98_11540	COG0702	epimerase
NRK98_11545	COG2914	Belongs to the UPF0125 (RnfH) family
NRK98_11550	COG2867	negative regulation of translational initiation
NRK98_11555	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NRK98_11570	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NRK98_11575	COG0583	DNA-binding transcription factor activity
NRK98_11580	COG3048	D-serine ammonia-lyase activity
NRK98_11590	COG0659	secondary active sulfate transmembrane transporter activity
NRK98_11595	COG0538	isocitrate dehydrogenase activity
NRK98_11600	COG2207	Transcriptional regulator
NRK98_11620	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRK98_11635	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NRK98_11640	COG1263	PTS System
NRK98_11640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRK98_11645	COG1609	Transcriptional regulator
NRK98_11655	COG0456	acetyltransferase
NRK98_11660	COG3081	Nucleoid-associated protein
NRK98_11670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRK98_11670	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRK98_11670	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRK98_11680	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRK98_11680	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRK98_11680	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRK98_11690	COG1187	pseudouridine synthase activity
NRK98_11700	COG0482	sulfurtransferase activity
NRK98_11705	COG2915	High frequency lysogenization protein hflD homolog
NRK98_11710	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NRK98_11715	COG2850	peptidyl-arginine hydroxylation
NRK98_11725	COG3153	acetyltransferase
NRK98_11735	COG0625	glutathione transferase activity
NRK98_11740	COG0259	pyridoxamine-phosphate oxidase activity
NRK98_11755	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NRK98_11755	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NRK98_11760	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NRK98_11775	COG0457	Tetratricopeptide repeat
NRK98_11780	COG3088	subunit of a heme lyase
NRK98_11780	COG4235	cytochrome complex assembly
NRK98_11785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NRK98_11790	COG1138	Cytochrome C-type biogenesis protein
NRK98_11795	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
NRK98_11800	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NRK98_11805	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NRK98_11810	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NRK98_11825	COG0835	chemotaxis
NRK98_11835	COG1192	Involved in chromosome partitioning
NRK98_11845	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NRK98_11850	COG2201	protein-glutamate methylesterase activity
NRK98_11855	COG2198	Histidine kinase
NRK98_11855	COG0643	Histidine kinase
NRK98_11855	COG0784	Response regulator, receiver
NRK98_11860	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
NRK98_11885	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NRK98_11895	COG1684	flagellar biosynthetic protein fliR
NRK98_11950	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NRK98_11960	COG1677	Flagellar hook-basal body complex protein FliE
NRK98_11980	COG0798	PFAM Bile acid sodium symporter
NRK98_11995	COG0640	Transcriptional regulator
NRK98_12000	COG1342	Belongs to the UPF0251 family
NRK98_12015	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NRK98_12020	COG1073	alpha beta
NRK98_12020	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
NRK98_12020	COG3064	Membrane
NRK98_12025	COG2994	toxin metabolic process
NRK98_12035	COG2274	protein secretion by the type I secretion system
NRK98_12045	COG2274	protein secretion by the type I secretion system
NRK98_12065	COG1737	Transcriptional regulator
NRK98_12070	COG0469	pyruvate kinase activity
NRK98_12085	COG1960	acyl-CoA dehydrogenase activity
NRK98_12095	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NRK98_12105	COG0243	molybdopterin cofactor binding
NRK98_12110	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NRK98_12115	COG0583	DNA-binding transcription factor activity
NRK98_12150	COG1012	belongs to the aldehyde dehydrogenase family
NRK98_12150	COG1454	alcohol dehydrogenase
NRK98_12160	COG1012	belongs to the aldehyde dehydrogenase family
NRK98_12160	COG1454	alcohol dehydrogenase
NRK98_12165	COG1882	Formate acetyltransferase
NRK98_12170	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NRK98_12180	COG4869	propanediol catabolic process
NRK98_12200	COG5002	protein histidine kinase activity
NRK98_12205	COG0745	RESPONSE REGULATOR receiver
NRK98_12210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRK98_12215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRK98_12235	COG1376	ErfK ybiS ycfS ynhG family protein
NRK98_12235	COG1388	LysM domain
NRK98_12250	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
NRK98_12255	COG0791	NLP P60 protein
NRK98_12265	COG3118	belongs to the thioredoxin family
NRK98_12275	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NRK98_12280	COG0788	formyltetrahydrofolate deformylase activity
NRK98_12290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRK98_12310	COG0366	Alpha amylase catalytic
NRK98_12315	COG0739	heme binding
NRK98_12315	COG0741	lytic transglycosylase activity
NRK98_12315	COG1196	nuclear chromosome segregation
NRK98_12320	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NRK98_12325	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NRK98_12330	COG0673	inositol 2-dehydrogenase activity
NRK98_12375	COG1032	radical SAM domain protein
NRK98_12385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRK98_12390	COG1566	PFAM secretion protein HlyD family protein
NRK98_12400	COG1752	Esterase of the alpha-beta hydrolase superfamily
NRK98_12405	COG0733	neurotransmitter:sodium symporter activity
NRK98_12435	COG0281	malic enzyme
NRK98_12440	COG2207	Transcriptional regulator
NRK98_12445	COG0534	Mate efflux family protein
NRK98_12460	COG2233	PERMEase
NRK98_12465	COG0095	Lipoate-protein ligase
NRK98_12470	COG1115	amino acid carrier protein
NRK98_12475	COG0019	diaminopimelate decarboxylase activity
NRK98_12505	COG1126	abc transporter atp-binding protein
NRK98_12510	COG0765	amino acid transport
NRK98_12515	COG4597	amino acid ABC transporter
NRK98_12520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRK98_12535	COG1131	(ABC) transporter
NRK98_12540	COG0545	Peptidyl-prolyl cis-trans isomerase
NRK98_12575	COG5002	protein histidine kinase activity
NRK98_12580	COG0745	RESPONSE REGULATOR receiver
NRK98_12585	COG0346	lactoylglutathione lyase activity
NRK98_12590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NRK98_12595	COG1960	acyl-CoA dehydrogenase activity
NRK98_12600	COG3284	Transcriptional regulator
NRK98_12615	COG0697	spore germination
NRK98_12620	COG4565	transcriptional regulatory protein
NRK98_12625	COG3290	protein histidine kinase activity
NRK98_12630	COG0281	malic enzyme
NRK98_12645	COG1846	Transcriptional regulator
NRK98_12650	COG1566	PFAM secretion protein HlyD family protein
NRK98_12680	COG0602	queuosine metabolic process
NRK98_12685	COG1328	CTP reductase activity
NRK98_12700	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NRK98_12705	COG3115	cell septum assembly
NRK98_12710	COG1196	nuclear chromosome segregation
NRK98_12720	COG2860	membrane
NRK98_12730	COG3108	Peptidase M15
NRK98_12735	COG2989	Protein conserved in bacteria
NRK98_12750	COG0463	Glycosyl transferase, family 2
NRK98_12765	COG0366	Alpha amylase catalytic
NRK98_12800	COG3706	GGDEF domain
NRK98_12805	COG0037	tRNA processing
NRK98_12810	COG3590	peptidase
NRK98_12820	COG0488	(ABC) transporter
NRK98_12830	COG0531	amino acid
NRK98_12835	COG0814	amino acid
NRK98_12850	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NRK98_12855	COG1982	Orn Lys Arg decarboxylase major
NRK98_12860	COG0531	amino acid
NRK98_12865	COG3710	Transcriptional regulator
NRK98_12870	COG0825	malonyl-CoA metabolic process
NRK98_12880	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NRK98_12885	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NRK98_12890	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NRK98_12895	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NRK98_12900	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NRK98_12915	COG0750	zinc metalloprotease
NRK98_12920	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NRK98_12925	COG0575	Belongs to the CDS family
NRK98_12930	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NRK98_12935	COG0233	cytoplasmic translational termination
NRK98_12940	COG0528	UMP kinase activity
NRK98_12945	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NRK98_12950	COG0052	Belongs to the universal ribosomal protein uS2 family
NRK98_12955	COG0024	Methionine aminopeptidase
NRK98_12960	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NRK98_12965	COG2171	N-acyltransferase activity
NRK98_12995	COG0564	pseudouridine synthase activity
NRK98_13000	COG3098	single-species biofilm formation
NRK98_13025	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
NRK98_13035	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NRK98_13035	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NRK98_13050	COG1611	Belongs to the LOG family
NRK98_13055	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NRK98_13060	COG0473	3-isopropylmalate dehydrogenase activity
NRK98_13070	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
NRK98_13075	COG2363	Small membrane protein
NRK98_13085	COG0583	DNA-binding transcription factor activity
NRK98_13090	COG0840	transmembrane signaling receptor activity
NRK98_13095	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NRK98_13110	COG1477	protein flavinylation
NRK98_13115	COG2871	sodium ion transport
NRK98_13120	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NRK98_13125	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NRK98_13130	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NRK98_13135	COG1805	sodium ion transport
NRK98_13140	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NRK98_13145	COG0271	Belongs to the BolA IbaG family
NRK98_13150	COG2813	Specifically methylates the guanine in position
NRK98_13160	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NRK98_13170	COG2211	Major facilitator Superfamily
NRK98_13175	COG3248	Nucleoside-binding outer membrane protein
NRK98_13180	COG1666	GTP binding
NRK98_13185	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NRK98_13190	COG0693	protein deglycase activity
NRK98_13275	COG2771	luxR family
NRK98_13290	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NRK98_13290	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NRK98_13295	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NRK98_13305	COG1151	hydroxylamine reductase activity
NRK98_13310	COG0783	Belongs to the Dps family
NRK98_13335	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NRK98_13350	COG4221	oxidoreductase activity
NRK98_13360	COG0415	Belongs to the DNA photolyase family
NRK98_13365	COG0789	Transcriptional regulator
NRK98_13370	COG3272	Protein of unknown function (DUF1722)
NRK98_13400	COG1605	Chorismate mutase
NRK98_13400	COG0077	Prephenate dehydratase
NRK98_13425	COG1349	DNA-binding transcription factor activity
NRK98_13430	COG2084	Dehydrogenase
NRK98_13440	COG0235	Class ii aldolase
NRK98_13445	COG3622	Belongs to the hyi family
NRK98_13450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NRK98_13455	COG2610	gluconate transmembrane transporter activity
NRK98_13465	COG0840	transmembrane signaling receptor activity
NRK98_13475	COG0300	oxidoreductase activity
NRK98_13500	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NRK98_13530	COG0826	peptidase U32
NRK98_13535	COG1280	lysine exporter protein (LysE YggA)
NRK98_13545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NRK98_13555	COG0745	RESPONSE REGULATOR receiver
NRK98_13565	COG0643	Histidine kinase
NRK98_13565	COG2198	Histidine kinase
NRK98_13575	COG0835	chemotaxis
NRK98_13580	COG0840	transmembrane signaling receptor activity
NRK98_13590	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
NRK98_13595	COG2201	protein-glutamate methylesterase activity
NRK98_13600	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NRK98_13625	COG2199	diguanylate cyclase activity
NRK98_13625	COG2200	EAL domain
NRK98_13625	COG2203	Gaf domain
NRK98_13630	COG0826	peptidase U32
NRK98_13635	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NRK98_13640	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NRK98_13655	COG2200	EAL domain
NRK98_13660	COG0737	Belongs to the 5'-nucleotidase family
NRK98_13680	COG2204	response regulator
NRK98_13685	COG0545	Peptidyl-prolyl cis-trans isomerase
NRK98_13695	COG2900	Belongs to the SlyX family
NRK98_13700	COG1047	Peptidyl-prolyl cis-trans
NRK98_13715	COG0784	Response regulator, receiver
NRK98_13715	COG0835	chemotaxis
NRK98_13720	COG0429	hydrolase of the alpha beta-hydrolase fold
NRK98_13725	COG3089	Belongs to the UPF0270 family
NRK98_13735	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NRK98_13740	COG0463	Glycosyl transferase, family 2
NRK98_13745	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NRK98_13745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NRK98_13750	COG0726	polysaccharide deacetylase
NRK98_13755	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NRK98_13760	COG2076	Multidrug Resistance protein
NRK98_13765	COG2076	Multidrug Resistance protein
NRK98_13770	COG3954	Phosphoribulokinase
NRK98_13785	COG1765	OsmC-like protein
NRK98_13800	COG3397	chitin binding
NRK98_13815	COG2205	protein histidine kinase activity
NRK98_13815	COG2202	Pas domain
NRK98_13825	COG3655	Transcriptional regulator
NRK98_13835	COG2814	Major facilitator Superfamily
NRK98_13840	COG4771	TonB-dependent receptor
NRK98_13860	COG0748	coenzyme F420 binding
NRK98_13865	COG3721	Heme iron utilization protein
NRK98_13875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRK98_13880	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
NRK98_13910	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NRK98_13925	COG0488	(ABC) transporter
NRK98_13935	COG2252	PERMEase
NRK98_13940	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NRK98_13945	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NRK98_13950	COG3178	'Phosphotransferase
NRK98_13955	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
NRK98_13965	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NRK98_13970	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NRK98_13975	COG2967	ApaG domain
NRK98_13980	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NRK98_13990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NRK98_13995	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NRK98_14010	COG0318	PFAM AMP-dependent synthetase and ligase
NRK98_14015	COG3314	Sporulation integral membrane protein YlbJ
NRK98_14020	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NRK98_14025	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NRK98_14030	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NRK98_14035	COG0142	geranyltranstransferase activity
NRK98_14040	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
NRK98_14045	COG0330	HflC and HflK could
NRK98_14050	COG0330	HflC and HflK could
NRK98_14055	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NRK98_14060	COG1923	regulation of RNA biosynthetic process
NRK98_14065	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NRK98_14070	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NRK98_14080	COG0802	atpase or kinase
NRK98_14085	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NRK98_14085	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NRK98_14105	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NRK98_14110	COG2011	ABC-type metal ion transport system permease component
NRK98_14115	COG1464	Belongs to the NlpA lipoprotein family
NRK98_14125	COG0840	transmembrane signaling receptor activity
NRK98_14150	COG0784	Response regulator, receiver
NRK98_14150	COG2198	Histidine kinase
NRK98_14150	COG5002	protein histidine kinase activity
NRK98_14170	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
NRK98_14185	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NRK98_14190	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
NRK98_14200	COG2716	regulation of RNA biosynthetic process
NRK98_14205	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NRK98_14210	COG3013	Belongs to the UPF0304 family
NRK98_14220	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NRK98_14225	COG0280	phosphate acetyltransferase
NRK98_14225	COG0857	belongs to the CobB CobQ family
NRK98_14230	COG0440	acetolactate synthase activity
NRK98_14235	COG0028	Belongs to the TPP enzyme family
NRK98_14250	COG0671	phosphoesterase, PA-phosphatase related
NRK98_14260	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NRK98_14265	COG0473	3-isopropylmalate dehydrogenase activity
NRK98_14270	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NRK98_14275	COG0066	3-isopropylmalate dehydratase activity
NRK98_14290	COG4143	(ABC) transporter
NRK98_14300	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
NRK98_14305	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NRK98_14355	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NRK98_14360	COG0564	pseudouridine synthase activity
NRK98_14370	COG3300	MHYT domain
NRK98_14370	COG5001	Diguanylate cyclase
NRK98_14380	COG0459	protein refolding
NRK98_14385	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NRK98_14390	COG0534	Mate efflux family protein
NRK98_14395	COG3030	protein affecting phage T7 exclusion by the F plasmid
NRK98_14400	COG1027	Aspartate ammonia-lyase
NRK98_14405	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NRK98_14415	COG0477	Major facilitator Superfamily
NRK98_14425	COG3227	Zinc metalloprotease (Elastase)
NRK98_14430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRK98_14435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRK98_14445	COG0673	inositol 2-dehydrogenase activity
NRK98_14455	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NRK98_14460	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NRK98_14465	COG3036	rescue of stalled ribosome
NRK98_14470	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NRK98_14480	COG0138	bifunctional purine biosynthesis protein purh
NRK98_14505	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NRK98_14510	COG0358	DNA primase activity
NRK98_14515	COG1610	YqeY-like protein
NRK98_14520	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NRK98_14525	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NRK98_14540	COG1238	metal cluster binding
NRK98_14545	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NRK98_14550	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NRK98_14555	COG0585	pseudouridine synthase activity
NRK98_14565	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NRK98_14570	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NRK98_14575	COG0148	phosphopyruvate hydratase activity
NRK98_14580	COG0504	CTP synthase activity
NRK98_14585	COG3956	TIGRFAM MazG family protein
NRK98_14590	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NRK98_14595	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NRK98_14605	COG4807	Protein conserved in bacteria
NRK98_14610	COG3023	N-Acetylmuramoyl-L-alanine amidase
NRK98_14615	COG1349	DNA-binding transcription factor activity
NRK98_14625	COG2222	sugar isomerase
NRK98_14630	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRK98_14640	COG3716	PTS system mannose fructose sorbose family IID component
NRK98_14645	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRK98_14650	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NRK98_14660	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NRK98_14665	COG1381	Involved in DNA repair and RecF pathway recombination
NRK98_14675	COG0571	ribonuclease III activity
NRK98_14680	COG0681	Belongs to the peptidase S26 family
NRK98_14685	COG0481	GTPase activity
NRK98_14700	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
NRK98_14705	COG1595	DNA-templated transcription, initiation
NRK98_14710	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NRK98_14725	COG0354	folic acid binding
NRK98_14770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRK98_14780	COG0126	phosphoglycerate kinase activity
NRK98_14785	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NRK98_14790	COG1940	carbohydrate kinase activity
NRK98_14795	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NRK98_14810	COG4991	sh3 domain protein
NRK98_14815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NRK98_14830	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NRK98_14835	COG1028	Short-chain dehydrogenase reductase Sdr
NRK98_14845	COG2982	Protein involved in outer membrane biogenesis
NRK98_14850	COG1505	serine-type exopeptidase activity
NRK98_14855	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NRK98_14860	COG0765	amino acid transport
NRK98_14865	COG0765	amino acid transport
NRK98_14870	COG1126	abc transporter atp-binding protein
NRK98_14875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRK98_14880	COG1136	(ABC) transporter
NRK98_14880	COG0577	efflux transmembrane transporter activity
NRK98_14885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRK98_14890	COG0745	RESPONSE REGULATOR receiver
NRK98_14895	COG2205	protein histidine kinase activity
NRK98_14900	COG2816	NAD+ diphosphatase activity
NRK98_14930	COG2070	2-Nitropropane dioxygenase
NRK98_14955	COG1858	cytochrome C peroxidase
NRK98_14960	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
NRK98_14980	COG0513	Belongs to the DEAD box helicase family
NRK98_14990	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NRK98_14995	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NRK98_15015	COG0154	amidase activity
NRK98_15020	COG2957	Belongs to the agmatine deiminase family
NRK98_15030	COG2852	Protein conserved in bacteria
NRK98_15040	COG1902	pentaerythritol trinitrate reductase activity
NRK98_15050	COG0456	acetyltransferase
NRK98_15070	COG5001	Diguanylate cyclase
NRK98_15070	COG5002	protein histidine kinase activity
NRK98_15090	COG0714	Associated with various cellular activities
NRK98_15100	COG0456	acetyltransferase
NRK98_15110	COG1022	Amp-dependent synthetase and ligase
NRK98_15115	COG2918	glutathione biosynthetic process
NRK98_15120	COG0612	Peptidase, M16
NRK98_15125	COG1238	metal cluster binding
NRK98_15160	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NRK98_15165	COG0359	binds to the 23S rRNA
NRK98_15170	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NRK98_15175	COG0360	Binds together with S18 to 16S ribosomal RNA
NRK98_15180	COG1914	H( )-stimulated, divalent metal cation uptake system
NRK98_15190	COG0583	DNA-binding transcription factor activity
NRK98_15200	COG2814	Major facilitator Superfamily
NRK98_15220	COG0697	spore germination
NRK98_15225	COG2153	protein acetylation
NRK98_15240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NRK98_15260	COG0557	exoribonuclease II activity
NRK98_15265	COG3706	GGDEF domain
NRK98_15270	COG1854	S-ribosylhomocysteine lyase activity
NRK98_15285	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NRK98_15285	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NRK98_15345	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NRK98_15350	COG1047	Peptidyl-prolyl cis-trans
NRK98_15355	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NRK98_15360	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NRK98_15365	COG0196	riboflavin kinase activity
NRK98_15370	COG0728	peptidoglycan biosynthetic process
NRK98_15375	COG0268	Binds directly to 16S ribosomal RNA
NRK98_15380	COG0640	Transcriptional regulator
NRK98_15385	COG0583	DNA-binding transcription factor activity
NRK98_15395	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NRK98_15400	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NRK98_15405	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NRK98_15415	COG1051	belongs to the nudix hydrolase family
NRK98_15420	COG3066	DNA modification
NRK98_15430	COG0335	large ribosomal subunit rRNA binding
NRK98_15435	COG0336	Belongs to the RNA methyltransferase TrmD family
NRK98_15440	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NRK98_15445	COG0228	four-way junction DNA binding
NRK98_15450	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NRK98_15455	COG4137	Cytochrome C assembly protein
NRK98_15460	COG4536	flavin adenine dinucleotide binding
NRK98_15465	COG1959	2 iron, 2 sulfur cluster binding
NRK98_15470	COG1017	nitric oxide dioxygenase activity
NRK98_15470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NRK98_15475	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
NRK98_15480	COG0039	L-malate dehydrogenase activity
NRK98_15485	COG4160	amino acid transport
NRK98_15490	COG4215	(ABC) transporter
NRK98_15495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRK98_15500	COG1126	abc transporter atp-binding protein
NRK98_15505	COG1438	arginine binding
NRK98_15510	COG2837	iron assimilation
NRK98_15515	COG3842	ATPase activity
NRK98_15525	COG1840	ABC-type Fe3 transport system, periplasmic component
NRK98_15530	COG0347	Belongs to the P(II) protein family
NRK98_15545	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRK98_15565	COG1929	Belongs to the glycerate kinase type-1 family
NRK98_15570	COG2610	gluconate transmembrane transporter activity
NRK98_15575	COG3835	regulator
NRK98_15580	COG3112	Uncharacterised protein family (UPF0231)
NRK98_15610	COG0513	Belongs to the DEAD box helicase family
NRK98_15650	COG1448	Aminotransferase
NRK98_15665	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NRK98_15670	COG1328	CTP reductase activity
NRK98_15690	COG0793	Belongs to the peptidase S41A family
NRK98_15690	COG4946	Tricorn protease homolog
NRK98_15725	COG3397	chitin binding
NRK98_15730	COG0583	DNA-binding transcription factor activity
NRK98_15735	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NRK98_15740	COG4208	sulfate ABC transporter
NRK98_15745	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NRK98_15755	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NRK98_15760	COG3174	membrane
NRK98_15765	COG0110	maltose O-acetyltransferase activity
NRK98_15790	COG0165	Argininosuccinate lyase
NRK98_15800	COG0137	argininosuccinate synthase activity
NRK98_15810	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NRK98_15815	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NRK98_15825	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NRK98_15830	COG0460	homoserine dehydrogenase
NRK98_15830	COG0527	aspartate kinase activity
NRK98_15835	COG0626	cystathionine gamma-synthase activity
NRK98_15845	COG3708	Transcriptional regulator
NRK98_15845	COG2207	Transcriptional regulator
NRK98_15850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRK98_15855	COG0814	amino acid
NRK98_15860	COG1218	3'(2'),5'-bisphosphate nucleotidase
NRK98_15865	COG0494	nUDIX hydrolase
NRK98_15870	COG1011	Hydrolase
NRK98_15875	COG1902	pentaerythritol trinitrate reductase activity
NRK98_15885	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NRK98_15900	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
NRK98_15910	COG3156	type II secretion system protein K
NRK98_15915	COG4795	General secretion pathway protein
NRK98_15920	COG2165	general secretion pathway protein
NRK98_15930	COG2165	general secretion pathway protein
NRK98_15935	COG1459	type II secretion system
NRK98_15940	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NRK98_15950	COG3031	protein transport across the cell outer membrane
NRK98_15960	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NRK98_15965	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NRK98_15985	COG0456	acetyltransferase
NRK98_15990	COG3133	Outer membrane lipoprotein
NRK98_16005	COG2771	luxR family
NRK98_16010	COG3916	Acyl-homoserine-lactone synthase
NRK98_16020	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
NRK98_16025	COG1309	transcriptional regulator
NRK98_16035	COG2213	PTS system mannitol-specific
NRK98_16035	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRK98_16040	COG0246	Mannitol dehydrogenase
NRK98_16045	COG3722	fumarate hydratase activity
NRK98_16050	COG3263	regulation of cellular component size
NRK98_16075	COG1671	Belongs to the UPF0178 family
NRK98_16090	COG1988	membrane-bound metal-dependent
NRK98_16095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRK98_16100	COG0513	Belongs to the DEAD box helicase family
NRK98_16125	COG1575	Belongs to the MenA family. Type 1 subfamily
NRK98_16130	COG1169	isochorismate synthase
NRK98_16135	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NRK98_16140	COG0596	Alpha beta hydrolase
NRK98_16145	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NRK98_16150	COG1441	menaquinone biosynthetic process
NRK98_16155	COG0318	PFAM AMP-dependent synthetase and ligase
NRK98_16175	COG3121	Chaperone
NRK98_16180	COG3188	usher protein
NRK98_16190	COG3539	Fimbrial protein
NRK98_16200	COG3291	Pkd domain containing protein
NRK98_16205	COG2949	membrane
NRK98_16210	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NRK98_16220	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NRK98_16225	COG5380	lipid catabolic process
NRK98_16240	COG4533	DNA binding
NRK98_16250	COG2873	o-acetylhomoserine
NRK98_16260	COG1979	alcohol dehydrogenase
NRK98_16275	COG4221	oxidoreductase activity
NRK98_16295	COG1285	pathogenesis
NRK98_16315	COG1368	sulfuric ester hydrolase activity
NRK98_16320	COG1522	sequence-specific DNA binding
NRK98_16330	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NRK98_16335	COG1418	mRNA catabolic process
NRK98_16340	COG1546	Belongs to the CinA family
NRK98_16340	COG1058	Belongs to the CinA family
NRK98_16350	COG0842	Transport permease protein
NRK98_16350	COG1129	ABC transporter
NRK98_16365	COG0561	phosphatase activity
NRK98_16370	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NRK98_16390	COG1011	Hydrolase
NRK98_16405	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NRK98_16410	COG0019	diaminopimelate decarboxylase activity
NRK98_16420	COG1965	Belongs to the frataxin family
NRK98_16425	COG0400	carboxylic ester hydrolase activity
NRK98_16430	COG3072	Adenylate cyclase
NRK98_16435	COG0181	hydroxymethylbilane synthase activity
NRK98_16445	COG2959	enzyme of heme biosynthesis
NRK98_16460	COG1494	fructose-1,6-bisphosphatase
NRK98_16495	COG0456	acetyltransferase
NRK98_16500	COG1733	regulation of RNA biosynthetic process
NRK98_16520	COG3932	Exopolysaccharide synthesis, ExoD
NRK98_16525	COG0814	amino acid
NRK98_16545	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
NRK98_16555	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NRK98_16560	COG2022	thiamine diphosphate biosynthetic process
NRK98_16570	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NRK98_16575	COG0352	thiamine-phosphate diphosphorylase activity
NRK98_16580	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NRK98_16605	COG0745	RESPONSE REGULATOR receiver
NRK98_16610	COG0642	Histidine kinase
NRK98_16615	COG0189	ligase activity
NRK98_16640	COG1757	Na H antiporter
NRK98_16645	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NRK98_16665	COG2321	neutral zinc metallopeptidase
NRK98_16670	COG3700	Belongs to the class B bacterial acid phosphatase family
NRK98_16690	COG1366	Belongs to the anti-sigma-factor antagonist family
NRK98_16695	COG2172	sigma factor antagonist activity
NRK98_16700	COG0784	Response regulator, receiver
NRK98_16700	COG5002	protein histidine kinase activity
NRK98_16700	COG2205	protein histidine kinase activity
NRK98_16705	COG3437	response regulator, receiver
NRK98_16715	COG0477	Major facilitator Superfamily
NRK98_16730	COG0312	modulator of DNA gyrase
NRK98_16735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NRK98_16745	COG3164	Protein of unknown function
NRK98_16750	COG1530	ribonuclease E activity
NRK98_16755	COG0424	maF-like protein
NRK98_16760	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NRK98_16765	COG1792	Involved in formation and maintenance of cell shape
NRK98_16770	COG1077	Cell shape determining protein MreB Mrl
NRK98_16795	COG4968	Prepilin-type N-terminal cleavage methylation domain
NRK98_16800	COG2165	general secretion pathway protein
NRK98_16805	COG2165	general secretion pathway protein
NRK98_16815	COG1459	type II secretion system
NRK98_16820	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NRK98_16835	COG1450	Type ii and iii secretion system protein
NRK98_16865	COG2199	diguanylate cyclase activity
NRK98_16865	COG2200	EAL domain
NRK98_16870	COG2200	EAL domain
NRK98_16875	COG0387	Pfam Sodium calcium exchanger
NRK98_16880	COG2986	histidine ammonia-lyase
NRK98_16885	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NRK98_16890	COG0010	Belongs to the arginase family
NRK98_16895	COG1228	amidohydrolase
NRK98_16900	COG2188	Transcriptional regulator
NRK98_16905	COG0288	reversible hydration of carbon dioxide
NRK98_16915	COG2177	Part of the ABC transporter FtsEX involved in
NRK98_16920	COG2884	Cell division ATP-binding protein ftsE
NRK98_16925	COG0552	protein localization to endoplasmic reticulum
NRK98_16930	COG0742	ribosomal rna small subunit methyltransferase
NRK98_16955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRK98_16965	COG0741	lytic transglycosylase activity
NRK98_16975	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NRK98_16985	COG2095	MarC family integral membrane protein
NRK98_16995	COG1301	dicarboxylic acid transport
NRK98_17020	COG3714	YhhN family
NRK98_17035	COG2358	TRAP transporter, solute receptor (TAXI family
NRK98_17040	COG1770	oligopeptidase
NRK98_17055	COG4221	oxidoreductase activity
NRK98_17060	COG0583	DNA-binding transcription factor activity
NRK98_17065	COG2249	NAD(P)H dehydrogenase (quinone) activity
NRK98_17110	COG0203	ribosomal protein L17
NRK98_17115	COG0202	RNA polymerase activity
NRK98_17120	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NRK98_17125	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NRK98_17130	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NRK98_17135	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NRK98_17140	COG0201	protein transport
NRK98_17145	COG0200	Binds to the 23S rRNA
NRK98_17150	COG1841	ribosomal large subunit assembly
NRK98_17155	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NRK98_17160	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NRK98_17165	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NRK98_17170	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NRK98_17175	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NRK98_17180	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NRK98_17185	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NRK98_17190	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NRK98_17195	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NRK98_17200	COG0255	Belongs to the universal ribosomal protein uL29 family
NRK98_17205	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NRK98_17210	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NRK98_17215	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NRK98_17220	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NRK98_17225	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NRK98_17230	COG0089	rRNA binding
NRK98_17235	COG0088	Forms part of the polypeptide exit tunnel
NRK98_17240	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NRK98_17245	COG0051	transcription antitermination factor activity, RNA binding
NRK98_17265	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NRK98_17270	COG2183	response to ionizing radiation
NRK98_17290	COG0596	Alpha beta hydrolase
NRK98_17295	COG1040	competence protein
NRK98_17300	COG0316	Belongs to the HesB IscA family
NRK98_17300	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NRK98_17305	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NRK98_17310	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
NRK98_17315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRK98_17320	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NRK98_17325	COG4942	peptidase
NRK98_17335	COG1609	Transcriptional regulator
NRK98_17340	COG0800	Aldolase
NRK98_17345	COG0129	dihydroxy-acid dehydratase activity
NRK98_17350	COG3265	gluconokinase activity
NRK98_17355	COG2610	gluconate transmembrane transporter activity
NRK98_17360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRK98_17365	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NRK98_17375	COG0456	acetyltransferase
NRK98_17385	COG1490	D-aminoacyl-tRNA deacylase activity
NRK98_17390	COG1295	ribonuclease BN
NRK98_17395	COG1295	ribonuclease BN
NRK98_17400	COG1217	gtp-binding protein TYPA
NRK98_17405	COG0174	glutamine synthetase
NRK98_17415	COG3852	Histidine kinase
NRK98_17420	COG2204	response regulator
NRK98_17425	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NRK98_17430	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NRK98_17440	COG3078	GTPase activator activity
NRK98_17450	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NRK98_17460	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NRK98_17465	COG0408	coproporphyrinogen oxidase activity
NRK98_17470	COG0009	L-threonylcarbamoyladenylate synthase
NRK98_17480	COG0551	DNA topoisomerase type I activity
NRK98_17485	COG2922	Belongs to the Smg family
NRK98_17490	COG0758	DNA mediated transformation
NRK98_17500	COG0242	peptide deformylase activity
NRK98_17505	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NRK98_17510	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NRK98_17510	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NRK98_17515	COG0569	domain protein
NRK98_17520	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NRK98_17525	COG1322	Protein conserved in bacteria
NRK98_17545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRK98_17550	COG0686	Belongs to the AlaDH PNT family
NRK98_17555	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NRK98_17555	COG0519	Catalyzes the synthesis of GMP from XMP
NRK98_17565	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NRK98_17570	COG1396	sequence-specific DNA binding
NRK98_17575	COG1012	belongs to the aldehyde dehydrogenase family
NRK98_17585	COG2962	Rard protein
NRK98_17595	COG1280	lysine exporter protein (LysE YggA)
NRK98_17605	COG2391	methyltransferase activity
NRK98_17610	COG1280	lysine exporter protein (LysE YggA)
NRK98_17645	COG3161	chorismate lyase activity
NRK98_17665	COG0583	DNA-binding transcription factor activity
NRK98_17685	COG1943	Transposase
NRK98_17700	COG0210	DNA helicase
NRK98_17705	COG1744	ABC transporter substrate-binding protein PnrA-like
NRK98_17710	COG3845	ABC transporter
NRK98_17715	COG4603	Belongs to the binding-protein-dependent transport system permease family
NRK98_17720	COG1079	Belongs to the binding-protein-dependent transport system permease family
NRK98_17725	COG0583	DNA-binding transcription factor activity
NRK98_17745	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NRK98_17750	COG0385	Bile acid
NRK98_17755	COG0531	amino acid
NRK98_17760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRK98_17765	COG0531	amino acid
NRK98_17770	COG2731	YhcH YjgK YiaL family protein
NRK98_17775	COG3250	beta-galactosidase activity
NRK98_17780	COG1609	Transcriptional regulator
NRK98_17815	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NRK98_17820	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NRK98_17820	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NRK98_17825	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
NRK98_17830	COG3074	FtsZ-dependent cytokinesis
NRK98_17840	COG1045	serine acetyltransferase
NRK98_17850	COG0745	RESPONSE REGULATOR receiver
NRK98_17855	COG2205	protein histidine kinase activity
NRK98_17860	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NRK98_17865	COG0534	Mate efflux family protein
NRK98_17880	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NRK98_17885	COG2937	Belongs to the GPAT DAPAT family
NRK98_17890	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NRK98_17895	COG3161	chorismate lyase activity
NRK98_17900	COG1580	Controls the rotational direction of flagella during chemotaxis
NRK98_17920	COG0604	alcohol dehydrogenase
NRK98_17925	COG1609	Transcriptional regulator
NRK98_17945	COG1519	Transferase
NRK98_17950	COG0859	PFAM glycosyl transferase family 9
NRK98_17955	COG0463	Glycosyl transferase, family 2
NRK98_17960	COG0859	PFAM glycosyl transferase family 9
NRK98_17965	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NRK98_17970	COG2990	Protein conserved in bacteria
NRK98_17975	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NRK98_17985	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NRK98_17990	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NRK98_17995	COG2003	Belongs to the UPF0758 family
NRK98_18000	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NRK98_18005	COG0756	dUTP diphosphatase activity
NRK98_18010	COG1309	transcriptional regulator
NRK98_18015	COG0668	transmembrane transport
NRK98_18025	COG0166	Belongs to the GPI family
NRK98_18030	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NRK98_18035	COG0583	DNA-binding transcription factor activity
NRK98_18050	COG1042	CoA-binding domain protein
NRK98_18050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRK98_18050	COG0045	succinate-CoA ligase (ADP-forming) activity
NRK98_18080	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
NRK98_18085	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NRK98_18090	COG1739	Uncharacterized protein family UPF0029
NRK98_18095	COG0006	proline dipeptidase activity
NRK98_18100	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NRK98_18105	COG1250	3-hydroxyacyl-CoA dehydrogenase
NRK98_18105	COG1024	Enoyl-CoA hydratase
NRK98_18110	COG0183	Belongs to the thiolase family
NRK98_18135	COG0425	Belongs to the sulfur carrier protein TusA family
NRK98_18140	COG0251	oxidation-reduction process
NRK98_18150	COG2885	chlorophyll binding
NRK98_18160	COG2818	Glycosylase
NRK98_18165	COG0752	glycyl-tRNA synthetase alpha subunit
NRK98_18170	COG0751	glycine-tRNA ligase activity
NRK98_18180	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NRK98_18205	COG0814	amino acid
NRK98_18210	COG0348	domain, Protein
NRK98_18215	COG2188	Transcriptional regulator
NRK98_18230	COG1609	Transcriptional regulator
NRK98_18270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRK98_18295	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NRK98_18310	COG3118	belongs to the thioredoxin family
NRK98_18315	COG0513	Belongs to the DEAD box helicase family
NRK98_18320	COG0248	Ppx GppA phosphatase
NRK98_18335	COG0742	ribosomal rna small subunit methyltransferase
NRK98_18340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRK98_18360	COG0084	hydrolase, TatD family'
NRK98_18365	COG0805	protein transport
NRK98_18370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NRK98_18380	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NRK98_18385	COG3165	ubiquinone biosynthetic process from chorismate
NRK98_18395	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NRK98_18400	COG0402	S-adenosylhomocysteine deaminase activity
NRK98_18445	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NRK98_18450	COG0848	biopolymer transport protein
NRK98_18455	COG0811	peptide transport
NRK98_18460	COG0811	peptide transport
NRK98_18470	COG2771	luxR family
NRK98_18475	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NRK98_18480	COG1349	DNA-binding transcription factor activity
NRK98_18485	COG0745	RESPONSE REGULATOR receiver
NRK98_18490	COG2205	protein histidine kinase activity
NRK98_18500	COG4452	Inner membrane protein CreD
NRK98_18505	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NRK98_18510	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NRK98_18515	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NRK98_18520	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NRK98_18525	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NRK98_18530	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NRK98_18535	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NRK98_18545	COG0356	it plays a direct role in the translocation of protons across the membrane
NRK98_18555	COG1475	DNA binding
NRK98_18560	COG1192	Involved in chromosome partitioning
NRK98_18565	COG0357	Ribosomal RNA small subunit methyltransferase G
NRK98_18570	COG0445	tRNA wobble uridine modification
NRK98_18575	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NRK98_18580	COG4774	siderophore transport
NRK98_18585	COG4615	Cyclic peptide transporter
NRK98_18590	COG1120	ATPase activity
NRK98_18605	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NRK98_18610	COG0706	membrane insertase activity
NRK98_18615	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NRK98_18620	COG0594	ribonuclease P activity
NRK98_18625	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NRK98_18630	COG1126	abc transporter atp-binding protein
NRK98_18645	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NRK98_18650	COG0592	DNA-directed DNA polymerase activity
NRK98_18670	COG2378	regulation of single-species biofilm formation
NRK98_18675	COG0071	Belongs to the small heat shock protein (HSP20) family
NRK98_18680	COG0071	Belongs to the small heat shock protein (HSP20) family
NRK98_18685	COG3977	Valine--pyruvate aminotransferase
NRK98_18700	COG2814	Major facilitator Superfamily
NRK98_18710	COG2205	protein histidine kinase activity
NRK98_18735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NRK98_18740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRK98_18740	COG4191	Histidine kinase
NRK98_18745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRK98_18750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRK98_18755	COG1309	transcriptional regulator
NRK98_18790	COG2271	Major facilitator Superfamily
NRK98_18810	COG0561	phosphatase activity
NRK98_18815	COG2267	carboxylic ester hydrolase activity
NRK98_18825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NRK98_18830	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NRK98_18835	COG1758	RNA polymerase activity
NRK98_18845	COG0859	PFAM glycosyl transferase family 9
NRK98_18850	COG3642	lipopolysaccharide core region biosynthetic process
NRK98_18890	COG0589	response to stress
NRK98_18895	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NRK98_18905	COG1528	Iron-storage protein
NRK98_18910	COG2081	HI0933 family
NRK98_18915	COG2223	nitrite transmembrane transporter activity
NRK98_18925	COG3275	phosphorelay sensor kinase activity
NRK98_18930	COG3279	Response regulator of the LytR AlgR family
NRK98_18935	COG2223	nitrite transmembrane transporter activity
NRK98_18940	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NRK98_18945	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NRK98_18960	COG0583	DNA-binding transcription factor activity
NRK98_18965	COG4206	TonB-dependent receptor
NRK98_18970	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NRK98_19005	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NRK98_19010	COG2166	iron-sulfur cluster assembly
NRK98_19015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NRK98_19025	COG5001	Diguanylate cyclase
NRK98_19025	COG3300	MHYT domain
NRK98_19030	COG3245	cytochrome
NRK98_19035	COG1063	alcohol dehydrogenase
NRK98_19050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NRK98_19065	COG3306	glycosyltransferase involved in LPS biosynthesis
NRK98_19085	COG4774	siderophore transport
NRK98_19090	COG4607	ABC-type enterochelin transport system periplasmic component
NRK98_19095	COG4604	ABC transporter, ATP-binding protein
NRK98_19100	COG4605	iron ion homeostasis
NRK98_19105	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRK98_19110	COG1132	(ABC) transporter
NRK98_19115	COG1132	(ABC) transporter
NRK98_19115	COG2375	cellular response to nickel ion
NRK98_19140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NRK98_19155	COG1561	YicC-like family, N-terminal region
NRK98_19160	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NRK98_19165	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NRK98_19175	COG0789	Transcriptional regulator
NRK98_19180	COG3706	GGDEF domain
NRK98_19180	COG5001	Diguanylate cyclase
NRK98_19180	COG4251	negative regulation of phosphorylation
NRK98_19180	COG2203	Gaf domain
NRK98_19185	COG3084	Protein conserved in bacteria
NRK98_19195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NRK98_19200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NRK98_19205	COG3639	organic phosphonate transmembrane transporter activity
NRK98_19210	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NRK98_19215	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
NRK98_19225	COG1335	isochorismatase
NRK98_19235	COG1683	Conserved Protein
NRK98_19240	COG0204	Acyl-transferase
NRK98_19245	COG0204	Acyl-transferase
NRK98_19250	COG0606	chelatase, subunit chli
NRK98_19260	COG3978	acetolactate synthase activity
NRK98_19270	COG0129	dihydroxy-acid dehydratase activity
NRK98_19300	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NRK98_19305	COG0254	rRNA binding
NRK98_19310	COG0702	epimerase
NRK98_19315	COG0281	malic enzyme
NRK98_19325	COG2205	protein histidine kinase activity
NRK98_19330	COG0745	RESPONSE REGULATOR receiver
NRK98_19335	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NRK98_19370	COG4310	Domain of unknown function (DUF2172)
NRK98_19390	COG2089	acid synthase
NRK98_19400	COG1083	cytidylyl-transferase
NRK98_19420	COG0318	PFAM AMP-dependent synthetase and ligase
NRK98_19435	COG1215	transferase activity, transferring glycosyl groups
NRK98_19450	COG0438	transferase activity, transferring glycosyl groups
NRK98_19470	COG0529	Catalyzes the synthesis of activated sulfate
NRK98_19480	COG3848	Pyruvate phosphate dikinase
NRK98_19480	COG0574	Belongs to the PEP-utilizing enzyme family
NRK98_19485	COG0519	Catalyzes the synthesis of GMP from XMP
NRK98_19490	COG1213	nucleotidyl transferase
NRK98_19495	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NRK98_19500	COG1086	Polysaccharide biosynthesis protein
NRK98_19505	COG0366	Alpha amylase catalytic
NRK98_19515	COG3187	Heat shock protein
NRK98_19520	COG0443	Heat shock 70 kDa protein
NRK98_19525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NRK98_19530	COG3045	CreA protein
NRK98_19550	COG0174	glutamine synthetase
NRK98_19570	COG3842	ATPase activity
NRK98_19575	COG1176	ABC-type spermidine putrescine transport system, permease component I
NRK98_19580	COG1177	transmembrane transport
NRK98_19585	COG2258	MOSC domain
NRK98_19600	COG2050	protein possibly involved in aromatic compounds catabolism
NRK98_19605	COG0514	ATP-dependent DNA helicase (RecQ)
NRK98_19615	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NRK98_19625	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NRK98_19630	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NRK98_19640	COG2239	Acts as a magnesium transporter
NRK98_19645	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NRK98_19645	COG1648	precorrin-2 dehydrogenase activity
NRK98_19650	COG2116	formate transmembrane transporter activity
NRK98_19660	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NRK98_19670	COG0477	Major facilitator Superfamily
NRK98_19680	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NRK98_19685	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NRK98_19695	COG0018	arginyl-trna synthetase
NRK98_19705	COG1595	DNA-templated transcription, initiation
NRK98_19710	COG3806	Anti-sigma factor
NRK98_19715	COG1968	undecaprenyl-diphosphatase activity
NRK98_19725	COG0667	Aldo Keto reductase
NRK98_19730	COG2017	converts alpha-aldose to the beta-anomer
NRK98_19735	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NRK98_19745	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NRK98_19750	COG1609	Transcriptional regulator
NRK98_19755	COG3250	beta-galactosidase activity
NRK98_19805	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NRK98_19810	COG1288	antiporter activity
NRK98_19815	COG1438	arginine binding
NRK98_19820	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
NRK98_19825	COG0540	Belongs to the ATCase OTCase family
NRK98_19845	COG0688	phosphatidylethanolamine metabolic process
NRK98_19860	COG3040	lipid binding
NRK98_19865	COG2207	Transcriptional regulator
NRK98_19870	COG1979	alcohol dehydrogenase
NRK98_19875	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NRK98_19880	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NRK98_19890	COG3681	Belongs to the UPF0597 family
NRK98_19900	COG0446	pyridine nucleotide-disulphide oxidoreductase
NRK98_19905	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NRK98_19910	COG0564	pseudouridine synthase activity
NRK98_19920	COG0542	response to heat
NRK98_19925	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NRK98_19930	COG2502	aspartate--ammonia ligase
NRK98_19935	COG1522	sequence-specific DNA binding
NRK98_19945	COG5413	integral membrane protein
NRK98_19950	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NRK98_19950	COG0617	tRNA 3'-terminal CCA addition
NRK98_19950	COG3620	sequence-specific DNA binding
NRK98_19955	COG1028	Short-chain dehydrogenase reductase Sdr
NRK98_19970	COG2205	protein histidine kinase activity
NRK98_19980	COG2204	response regulator
NRK98_19995	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
NRK98_20025	COG0243	molybdopterin cofactor binding
NRK98_20030	COG3005	denitrification pathway
NRK98_20035	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NRK98_20055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NRK98_20060	COG0569	domain protein
NRK98_20065	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NRK98_20090	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NRK98_20105	COG0250	Participates in transcription elongation, termination and antitermination
NRK98_20110	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NRK98_20115	COG0081	regulation of translation
NRK98_20120	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NRK98_20125	COG0222	ribosome binding
NRK98_20130	COG0085	RNA polymerase activity
NRK98_20135	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NRK98_20140	COG2964	Protein conserved in bacteria
NRK98_20145	COG0251	oxidation-reduction process
NRK98_20160	COG2168	tRNA wobble position uridine thiolation
NRK98_20165	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NRK98_20170	COG0049	tRNA binding
NRK98_20175	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NRK98_20180	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NRK98_20185	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NRK98_20225	COG2252	PERMEase
NRK98_20235	COG1461	Dihydroxyacetone kinase
NRK98_20250	COG3284	Transcriptional regulator
NRK98_20260	COG2957	Belongs to the agmatine deiminase family
NRK98_20280	COG0628	permease
NRK98_20285	COG0671	phosphoesterase, PA-phosphatase related
NRK98_20310	COG1247	-acetyltransferase
NRK98_20330	COG3706	GGDEF domain
NRK98_20340	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NRK98_20350	COG1175	transmembrane transport
NRK98_20375	COG0583	DNA-binding transcription factor activity
NRK98_20385	COG1741	Belongs to the pirin family
NRK98_20390	COG2259	Doxx family
NRK98_20395	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NRK98_20400	COG1074	ATP-dependent DNA helicase activity
NRK98_20405	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NRK98_20415	COG0583	DNA-binding transcription factor activity
NRK98_20425	COG0346	lactoylglutathione lyase activity
NRK98_20470	COG2203	Gaf domain
NRK98_20470	COG3706	GGDEF domain
NRK98_20470	COG5001	Diguanylate cyclase
NRK98_20470	COG4251	negative regulation of phosphorylation
NRK98_20475	COG4771	TonB-dependent receptor
NRK98_20510	COG2197	response regulator
NRK98_20515	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NRK98_20525	COG3047	cAMP biosynthetic process
NRK98_20530	COG0840	transmembrane signaling receptor activity
NRK98_20555	COG3135	benzoate transporter
NRK98_20560	COG1396	sequence-specific DNA binding
NRK98_20590	COG2926	Belongs to the UPF0265 family
NRK98_20600	COG3028	Belongs to the UPF0307 family
NRK98_20605	COG0312	modulator of DNA gyrase
NRK98_20610	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NRK98_20615	COG5007	Belongs to the BolA IbaG family
NRK98_20625	COG2854	intermembrane phospholipid transfer
NRK98_20630	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NRK98_20635	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NRK98_20640	COG1127	ABC transporter
NRK98_20645	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NRK98_20645	COG0517	IMP dehydrogenase activity
NRK98_20650	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NRK98_20655	COG3117	lipopolysaccharide transmembrane transporter activity
NRK98_20660	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NRK98_20665	COG1137	ATPase activity
NRK98_20670	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NRK98_20680	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRK98_20685	COG1660	Displays ATPase and GTPase activities
NRK98_20690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRK98_20695	COG3711	transcriptional antiterminator
NRK98_20695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRK98_20710	COG3964	amidohydrolase
NRK98_20740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NRK98_20745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NRK98_20755	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NRK98_20760	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NRK98_20765	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NRK98_20770	COG0723	plastoquinol--plastocyanin reductase activity
NRK98_20775	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NRK98_20780	COG2857	Cytochrome c1
NRK98_20785	COG0625	glutathione transferase activity
NRK98_20790	COG2969	positive regulation of protein catabolic process
NRK98_20795	COG2823	Periplasmic or secreted lipoprotein
NRK98_20800	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NRK98_20805	COG0792	nuclease activity
NRK98_20810	COG3107	peptidoglycan biosynthetic process
NRK98_20815	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NRK98_20825	COG2001	Belongs to the MraZ family
NRK98_20830	COG0275	rRNA processing
NRK98_20835	COG3116	cell division
NRK98_20840	COG0768	penicillin binding
NRK98_20850	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NRK98_20855	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NRK98_20860	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NRK98_20865	COG0772	Belongs to the SEDS family
NRK98_20870	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NRK98_20875	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NRK98_20880	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NRK98_20885	COG0849	cell division
NRK98_20890	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NRK98_20895	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NRK98_20905	COG0653	protein targeting
NRK98_20915	COG0494	nUDIX hydrolase
NRK98_20920	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
NRK98_20925	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
NRK98_20935	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NRK98_20940	COG1459	type II secretion system
NRK98_20945	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NRK98_20970	COG2186	Transcriptional regulator
NRK98_20975	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NRK98_20980	COG0508	dehydrogenase complex catalyzes the overall conversion of
NRK98_20985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NRK98_20995	COG0840	transmembrane signaling receptor activity
NRK98_21000	COG0840	transmembrane signaling receptor activity
NRK98_21005	COG1752	Esterase of the alpha-beta hydrolase superfamily
NRK98_21010	COG1049	propionate catabolic process, 2-methylcitrate cycle
NRK98_21015	COG2200	EAL domain
NRK98_21025	COG1280	lysine exporter protein (LysE YggA)
NRK98_21035	COG0523	cobalamin synthesis protein
NRK98_21040	COG0477	Major facilitator Superfamily
NRK98_21055	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NRK98_21060	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NRK98_21095	COG3314	Sporulation integral membrane protein YlbJ
NRK98_21100	COG0784	Response regulator, receiver
NRK98_21100	COG0835	chemotaxis
NRK98_21110	COG1444	tRNA N-acetyltransferase activity
NRK98_21135	COG1803	Methylglyoxal synthase
NRK98_21150	COG0252	asparaginase activity
NRK98_21165	COG1609	Transcriptional regulator
NRK98_21170	COG1263	PTS System
NRK98_21170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRK98_21175	COG0366	Alpha amylase catalytic
NRK98_21180	COG0110	maltose O-acetyltransferase activity
NRK98_21200	COG1012	belongs to the aldehyde dehydrogenase family
NRK98_21205	COG1177	transmembrane transport
NRK98_21210	COG1176	ABC-type spermidine putrescine transport system, permease component I
NRK98_21215	COG3842	ATPase activity
NRK98_21220	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NRK98_21225	COG0583	DNA-binding transcription factor activity
NRK98_21230	COG1757	Na H antiporter
NRK98_21260	COG0297	glycogen (starch) synthase activity
NRK98_21265	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NRK98_21270	COG2813	Specifically methylates the guanine in position
NRK98_21275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NRK98_21280	COG2203	Gaf domain
NRK98_21280	COG3706	GGDEF domain
NRK98_21280	COG4251	negative regulation of phosphorylation
NRK98_21280	COG5001	Diguanylate cyclase
NRK98_21290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRK98_21300	COG2995	paraquat-inducible protein a
NRK98_21305	COG3008	intermembrane lipid transfer
NRK98_21305	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NRK98_21310	COG3009	Protein conserved in bacteria
NRK98_21325	COG3240	lipase activity
NRK98_21330	COG3111	PFAM Bacterial OB fold (BOF) protein
NRK98_21340	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
NRK98_21345	COG1194	a g-specific adenine glycosylase
NRK98_21355	COG3267	Type II secretory pathway component ExeA
NRK98_21355	COG3409	Peptidoglycan-binding domain 1 protein
NRK98_21360	COG0617	tRNA 3'-terminal CCA addition
NRK98_21375	COG1346	cytolysis
NRK98_21380	COG1380	Effector of murein hydrolase LrgA
NRK98_21385	COG0583	DNA-binding transcription factor activity
NRK98_21415	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NRK98_21420	COG0306	phosphate transporter
NRK98_21425	COG1392	Phosphate transport regulator
NRK98_21440	COG1560	Kdo2-lipid A biosynthetic process
NRK98_21445	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NRK98_21445	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NRK98_21450	COG1538	Outer membrane efflux protein
NRK98_21455	COG0494	nUDIX hydrolase
NRK98_21460	COG3151	Protein conserved in bacteria
NRK98_21470	COG3150	esterase
NRK98_21475	COG1051	belongs to the nudix hydrolase family
NRK98_21490	COG1566	PFAM secretion protein HlyD family protein
NRK98_21495	COG1289	transmembrane transporter activity
NRK98_21515	COG0583	DNA-binding transcription factor activity
NRK98_21525	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NRK98_21575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NRK98_21595	COG0204	Acyl-transferase
NRK98_21600	COG1842	Phage shock protein A
NRK98_21615	COG2827	Endonuclease containing a URI domain
NRK98_21625	COG2962	Rard protein
NRK98_21630	COG1573	uracil-dna glycosylase
NRK98_21635	COG0697	spore germination
NRK98_21640	COG0583	DNA-binding transcription factor activity
NRK98_21645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NRK98_21650	COG1121	(ABC) transporter
NRK98_21655	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
NRK98_21675	COG0739	heme binding
NRK98_21685	COG3068	Protein conserved in bacteria
NRK98_21705	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NRK98_21710	COG1546	Belongs to the CinA family
NRK98_21715	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NRK98_21725	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NRK98_21730	COG0527	aspartate kinase activity
NRK98_21735	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NRK98_21770	COG1686	Belongs to the peptidase S11 family
NRK98_21775	COG0586	Pfam SNARE associated Golgi protein
NRK98_21780	COG1253	flavin adenine dinucleotide binding
NRK98_21785	COG0525	valine-tRNA ligase activity
NRK98_21790	COG2927	DNA polymerase III (CHI subunit)
NRK98_21795	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NRK98_21800	COG0795	lipopolysaccharide-transporting ATPase activity
NRK98_21805	COG0795	lipopolysaccharide-transporting ATPase activity