locus-tag	class	description
NRZ32_00020	COG0793	Belongs to the peptidase S41A family
NRZ32_00020	COG4946	Tricorn protease homolog
NRZ32_00040	COG1328	CTP reductase activity
NRZ32_00045	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NRZ32_00060	COG1448	Aminotransferase
NRZ32_00100	COG0513	Belongs to the DEAD box helicase family
NRZ32_00130	COG3112	Uncharacterised protein family (UPF0231)
NRZ32_00135	COG3835	regulator
NRZ32_00140	COG2610	gluconate transmembrane transporter activity
NRZ32_00145	COG1929	Belongs to the glycerate kinase type-1 family
NRZ32_00160	COG0583	DNA-binding transcription factor activity
NRZ32_00165	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRZ32_00180	COG0347	Belongs to the P(II) protein family
NRZ32_00185	COG1840	ABC-type Fe3 transport system, periplasmic component
NRZ32_00195	COG3842	ATPase activity
NRZ32_00200	COG2837	iron assimilation
NRZ32_00205	COG1438	arginine binding
NRZ32_00210	COG1126	abc transporter atp-binding protein
NRZ32_00215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ32_00220	COG4215	(ABC) transporter
NRZ32_00225	COG4160	amino acid transport
NRZ32_00230	COG0039	L-malate dehydrogenase activity
NRZ32_00235	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
NRZ32_00240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NRZ32_00240	COG1017	nitric oxide dioxygenase activity
NRZ32_00245	COG1959	2 iron, 2 sulfur cluster binding
NRZ32_00250	COG4536	flavin adenine dinucleotide binding
NRZ32_00255	COG4137	Cytochrome C assembly protein
NRZ32_00260	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NRZ32_00265	COG0228	four-way junction DNA binding
NRZ32_00270	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NRZ32_00275	COG0336	Belongs to the RNA methyltransferase TrmD family
NRZ32_00280	COG0335	large ribosomal subunit rRNA binding
NRZ32_00290	COG3066	DNA modification
NRZ32_00295	COG1051	belongs to the nudix hydrolase family
NRZ32_00305	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NRZ32_00310	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NRZ32_00315	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NRZ32_00325	COG0583	DNA-binding transcription factor activity
NRZ32_00330	COG0640	Transcriptional regulator
NRZ32_00335	COG0268	Binds directly to 16S ribosomal RNA
NRZ32_00340	COG0728	peptidoglycan biosynthetic process
NRZ32_00345	COG0196	riboflavin kinase activity
NRZ32_00350	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NRZ32_00355	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NRZ32_00360	COG1047	Peptidyl-prolyl cis-trans
NRZ32_00365	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NRZ32_00370	COG4970	Tfp pilus assembly protein FimT
NRZ32_00425	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NRZ32_00425	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NRZ32_00440	COG1854	S-ribosylhomocysteine lyase activity
NRZ32_00445	COG3706	GGDEF domain
NRZ32_00450	COG0557	exoribonuclease II activity
NRZ32_00460	COG4735	regulation of single-species biofilm formation
NRZ32_00465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NRZ32_00475	COG2153	protein acetylation
NRZ32_00480	COG0697	spore germination
NRZ32_00500	COG2814	Major facilitator Superfamily
NRZ32_00510	COG0583	DNA-binding transcription factor activity
NRZ32_00520	COG1914	H( )-stimulated, divalent metal cation uptake system
NRZ32_00525	COG0360	Binds together with S18 to 16S ribosomal RNA
NRZ32_00530	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NRZ32_00535	COG0359	binds to the 23S rRNA
NRZ32_00540	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NRZ32_00565	COG1064	alcohol dehydrogenase
NRZ32_00570	COG1238	metal cluster binding
NRZ32_00575	COG0612	Peptidase, M16
NRZ32_00580	COG2918	glutathione biosynthetic process
NRZ32_00590	COG1022	Amp-dependent synthetase and ligase
NRZ32_00600	COG0456	acetyltransferase
NRZ32_00610	COG0714	Associated with various cellular activities
NRZ32_00630	COG5001	Diguanylate cyclase
NRZ32_00655	COG1902	pentaerythritol trinitrate reductase activity
NRZ32_00670	COG2957	Belongs to the agmatine deiminase family
NRZ32_00675	COG0154	amidase activity
NRZ32_00695	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NRZ32_00700	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NRZ32_00710	COG0513	Belongs to the DEAD box helicase family
NRZ32_00735	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
NRZ32_00740	COG1858	cytochrome C peroxidase
NRZ32_00765	COG2070	2-Nitropropane dioxygenase
NRZ32_00805	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NRZ32_00820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRZ32_00850	COG0745	RESPONSE REGULATOR receiver
NRZ32_00855	COG3104	oligopeptide transport
NRZ32_00860	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NRZ32_00865	COG1555	photosystem II stabilization
NRZ32_00875	COG2350	Protein conserved in bacteria
NRZ32_00880	COG2917	probably involved in intracellular septation
NRZ32_00885	COG0076	glutamate decarboxylase activity
NRZ32_00890	COG1272	protein, Hemolysin III
NRZ32_00895	COG0569	domain protein
NRZ32_00895	COG2985	domain, Protein
NRZ32_00920	COG0564	pseudouridine synthase activity
NRZ32_00925	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NRZ32_00955	COG2816	NAD+ diphosphatase activity
NRZ32_00960	COG2205	protein histidine kinase activity
NRZ32_00965	COG0745	RESPONSE REGULATOR receiver
NRZ32_00970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRZ32_00975	COG1136	(ABC) transporter
NRZ32_00975	COG0577	efflux transmembrane transporter activity
NRZ32_00980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ32_00985	COG1126	abc transporter atp-binding protein
NRZ32_00990	COG0765	amino acid transport
NRZ32_00995	COG0765	amino acid transport
NRZ32_01000	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NRZ32_01005	COG1505	serine-type exopeptidase activity
NRZ32_01010	COG2982	Protein involved in outer membrane biogenesis
NRZ32_01020	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ32_01025	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NRZ32_01040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NRZ32_01045	COG4991	sh3 domain protein
NRZ32_01055	COG2816	NAD+ diphosphatase activity
NRZ32_01060	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NRZ32_01065	COG1940	carbohydrate kinase activity
NRZ32_01070	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NRZ32_01075	COG0126	phosphoglycerate kinase activity
NRZ32_01085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRZ32_01130	COG0354	folic acid binding
NRZ32_01135	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
NRZ32_01145	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NRZ32_01150	COG1595	DNA-templated transcription, initiation
NRZ32_01155	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
NRZ32_01170	COG0481	GTPase activity
NRZ32_01175	COG0681	Belongs to the peptidase S26 family
NRZ32_01180	COG0571	ribonuclease III activity
NRZ32_01190	COG1381	Involved in DNA repair and RecF pathway recombination
NRZ32_01195	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NRZ32_01205	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NRZ32_01210	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ32_01215	COG3716	PTS system mannose fructose sorbose family IID component
NRZ32_01225	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ32_01230	COG2222	sugar isomerase
NRZ32_01240	COG1349	DNA-binding transcription factor activity
NRZ32_01245	COG3023	N-Acetylmuramoyl-L-alanine amidase
NRZ32_01250	COG4807	Protein conserved in bacteria
NRZ32_01260	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NRZ32_01265	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NRZ32_01270	COG3956	TIGRFAM MazG family protein
NRZ32_01275	COG0504	CTP synthase activity
NRZ32_01280	COG0148	phosphopyruvate hydratase activity
NRZ32_01285	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NRZ32_01290	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NRZ32_01300	COG0585	pseudouridine synthase activity
NRZ32_01305	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NRZ32_01310	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NRZ32_01315	COG1238	metal cluster binding
NRZ32_01330	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NRZ32_01335	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NRZ32_01340	COG1610	YqeY-like protein
NRZ32_01345	COG0358	DNA primase activity
NRZ32_01350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NRZ32_01375	COG0138	bifunctional purine biosynthesis protein purh
NRZ32_01385	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NRZ32_01390	COG3036	rescue of stalled ribosome
NRZ32_01395	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NRZ32_01400	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NRZ32_01410	COG0673	inositol 2-dehydrogenase activity
NRZ32_01420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ32_01425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ32_01430	COG3227	Zinc metalloprotease (Elastase)
NRZ32_01440	COG0477	Major facilitator Superfamily
NRZ32_01450	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NRZ32_01455	COG1027	Aspartate ammonia-lyase
NRZ32_01460	COG3030	protein affecting phage T7 exclusion by the F plasmid
NRZ32_01465	COG0534	Mate efflux family protein
NRZ32_01470	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NRZ32_01475	COG0459	protein refolding
NRZ32_01485	COG3300	MHYT domain
NRZ32_01485	COG5001	Diguanylate cyclase
NRZ32_01500	COG0784	Response regulator, receiver
NRZ32_01500	COG0835	chemotaxis
NRZ32_01505	COG2755	lipolytic protein G-D-S-L family
NRZ32_01510	COG4181	ATPase activity
NRZ32_01515	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
NRZ32_01520	COG1090	epimerase
NRZ32_01525	COG2200	EAL domain
NRZ32_01530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRZ32_01535	COG2234	aminopeptidase activity
NRZ32_01535	COG4935	Belongs to the peptidase S8 family
NRZ32_01540	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NRZ32_01545	COG3171	Protein conserved in bacteria
NRZ32_01550	COG2066	Belongs to the glutaminase family
NRZ32_01555	COG2897	thiosulfate sulfurtransferase activity
NRZ32_01560	COG1404	Belongs to the peptidase S8 family
NRZ32_01570	COG1132	(ABC) transporter
NRZ32_01600	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
NRZ32_01605	COG3300	MHYT domain
NRZ32_01605	COG5001	Diguanylate cyclase
NRZ32_01625	COG4628	conserved protein (DUF2132)
NRZ32_01630	COG0688	phosphatidylethanolamine metabolic process
NRZ32_01635	COG1162	GTPase activity
NRZ32_01640	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NRZ32_01680	COG1278	Cold shock
NRZ32_01690	COG0840	transmembrane signaling receptor activity
NRZ32_01695	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NRZ32_01745	COG0848	biopolymer transport protein
NRZ32_01750	COG0811	peptide transport
NRZ32_01755	COG0811	peptide transport
NRZ32_01770	COG4174	ABC transporter (Permease)
NRZ32_01775	COG4239	(ABC) transporter, permease
NRZ32_01785	COG0444	Belongs to the ABC transporter superfamily
NRZ32_01790	COG4608	Belongs to the ABC transporter superfamily
NRZ32_01805	COG1464	Belongs to the NlpA lipoprotein family
NRZ32_01810	COG2011	ABC-type metal ion transport system permease component
NRZ32_01815	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NRZ32_01835	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NRZ32_01835	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NRZ32_01840	COG0802	atpase or kinase
NRZ32_01850	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NRZ32_01855	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NRZ32_01860	COG1923	regulation of RNA biosynthetic process
NRZ32_01865	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NRZ32_01870	COG0330	HflC and HflK could
NRZ32_01875	COG0330	HflC and HflK could
NRZ32_01880	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
NRZ32_01885	COG0142	geranyltranstransferase activity
NRZ32_01890	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NRZ32_01895	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NRZ32_01900	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NRZ32_01905	COG3314	Sporulation integral membrane protein YlbJ
NRZ32_01910	COG0318	PFAM AMP-dependent synthetase and ligase
NRZ32_01925	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NRZ32_01930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NRZ32_01940	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NRZ32_01945	COG2967	ApaG domain
NRZ32_01950	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NRZ32_01955	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NRZ32_01965	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
NRZ32_01970	COG3178	'Phosphotransferase
NRZ32_01975	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NRZ32_01980	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NRZ32_01985	COG2252	PERMEase
NRZ32_01995	COG0488	(ABC) transporter
NRZ32_02010	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NRZ32_02015	COG0741	lytic transglycosylase activity
NRZ32_02040	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
NRZ32_02045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ32_02055	COG3721	Heme iron utilization protein
NRZ32_02060	COG0748	coenzyme F420 binding
NRZ32_02080	COG4771	TonB-dependent receptor
NRZ32_02085	COG2814	Major facilitator Superfamily
NRZ32_02095	COG3655	Transcriptional regulator
NRZ32_02105	COG2202	Pas domain
NRZ32_02105	COG2205	protein histidine kinase activity
NRZ32_02120	COG3397	chitin binding
NRZ32_02140	COG1765	OsmC-like protein
NRZ32_02155	COG3954	Phosphoribulokinase
NRZ32_02160	COG2076	Multidrug Resistance protein
NRZ32_02165	COG2076	Multidrug Resistance protein
NRZ32_02170	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NRZ32_02175	COG0726	polysaccharide deacetylase
NRZ32_02180	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NRZ32_02180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NRZ32_02185	COG0463	Glycosyl transferase, family 2
NRZ32_02190	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NRZ32_02200	COG3089	Belongs to the UPF0270 family
NRZ32_02210	COG0835	chemotaxis
NRZ32_02210	COG0784	Response regulator, receiver
NRZ32_02220	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
NRZ32_02225	COG1047	Peptidyl-prolyl cis-trans
NRZ32_02230	COG2900	Belongs to the SlyX family
NRZ32_02240	COG0545	Peptidyl-prolyl cis-trans isomerase
NRZ32_02245	COG2204	response regulator
NRZ32_02265	COG0737	Belongs to the 5'-nucleotidase family
NRZ32_02270	COG2200	EAL domain
NRZ32_02285	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NRZ32_02295	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NRZ32_02300	COG0826	peptidase U32
NRZ32_02305	COG2199	diguanylate cyclase activity
NRZ32_02305	COG2200	EAL domain
NRZ32_02305	COG2203	Gaf domain
NRZ32_02330	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NRZ32_02335	COG2201	protein-glutamate methylesterase activity
NRZ32_02340	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
NRZ32_02350	COG0840	transmembrane signaling receptor activity
NRZ32_02355	COG0835	chemotaxis
NRZ32_02365	COG0643	Histidine kinase
NRZ32_02365	COG2198	Histidine kinase
NRZ32_02375	COG0745	RESPONSE REGULATOR receiver
NRZ32_02385	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NRZ32_02395	COG1280	lysine exporter protein (LysE YggA)
NRZ32_02400	COG0826	peptidase U32
NRZ32_02430	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NRZ32_02455	COG0300	oxidoreductase activity
NRZ32_02465	COG0840	transmembrane signaling receptor activity
NRZ32_02475	COG2610	gluconate transmembrane transporter activity
NRZ32_02480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NRZ32_02485	COG3622	Belongs to the hyi family
NRZ32_02490	COG0235	Class ii aldolase
NRZ32_02500	COG2084	Dehydrogenase
NRZ32_02505	COG1349	DNA-binding transcription factor activity
NRZ32_02530	COG0077	Prephenate dehydratase
NRZ32_02530	COG1605	Chorismate mutase
NRZ32_02560	COG3272	Protein of unknown function (DUF1722)
NRZ32_02565	COG0789	Transcriptional regulator
NRZ32_02570	COG0415	Belongs to the DNA photolyase family
NRZ32_02580	COG0300	oxidoreductase activity
NRZ32_02595	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NRZ32_02620	COG0783	Belongs to the Dps family
NRZ32_02625	COG1151	hydroxylamine reductase activity
NRZ32_02635	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NRZ32_02640	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NRZ32_02640	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NRZ32_02650	COG2771	luxR family
NRZ32_02710	COG0693	protein deglycase activity
NRZ32_02715	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NRZ32_02720	COG1666	GTP binding
NRZ32_02725	COG3248	Nucleoside-binding outer membrane protein
NRZ32_02730	COG2211	Major facilitator Superfamily
NRZ32_02740	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NRZ32_02750	COG2813	Specifically methylates the guanine in position
NRZ32_02755	COG0271	Belongs to the BolA IbaG family
NRZ32_02760	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NRZ32_02765	COG1805	sodium ion transport
NRZ32_02770	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NRZ32_02775	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NRZ32_02780	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NRZ32_02785	COG2871	sodium ion transport
NRZ32_02790	COG1477	protein flavinylation
NRZ32_02805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NRZ32_02810	COG0840	transmembrane signaling receptor activity
NRZ32_02815	COG0583	DNA-binding transcription factor activity
NRZ32_02825	COG2363	Small membrane protein
NRZ32_02830	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
NRZ32_02840	COG0473	3-isopropylmalate dehydrogenase activity
NRZ32_02845	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NRZ32_02850	COG1611	Belongs to the LOG family
NRZ32_02865	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NRZ32_02865	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NRZ32_02875	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
NRZ32_02900	COG3098	single-species biofilm formation
NRZ32_02905	COG0564	pseudouridine synthase activity
NRZ32_02935	COG2171	N-acyltransferase activity
NRZ32_02940	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NRZ32_02945	COG0024	Methionine aminopeptidase
NRZ32_02950	COG0052	Belongs to the universal ribosomal protein uS2 family
NRZ32_02955	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NRZ32_02960	COG0528	UMP kinase activity
NRZ32_02965	COG0233	cytoplasmic translational termination
NRZ32_02970	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NRZ32_02975	COG0575	Belongs to the CDS family
NRZ32_02980	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NRZ32_02985	COG0750	zinc metalloprotease
NRZ32_03000	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NRZ32_03005	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NRZ32_03010	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NRZ32_03015	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NRZ32_03020	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NRZ32_03030	COG0825	malonyl-CoA metabolic process
NRZ32_03035	COG3710	Transcriptional regulator
NRZ32_03040	COG0531	amino acid
NRZ32_03045	COG1982	Orn Lys Arg decarboxylase major
NRZ32_03050	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NRZ32_03065	COG0814	amino acid
NRZ32_03070	COG0531	amino acid
NRZ32_03080	COG0488	(ABC) transporter
NRZ32_03090	COG3590	peptidase
NRZ32_03100	COG3706	GGDEF domain
NRZ32_03135	COG0366	Alpha amylase catalytic
NRZ32_03150	COG0463	Glycosyl transferase, family 2
NRZ32_03165	COG2989	Protein conserved in bacteria
NRZ32_03170	COG3108	Peptidase M15
NRZ32_03180	COG2860	membrane
NRZ32_03190	COG1196	nuclear chromosome segregation
NRZ32_03195	COG3115	cell septum assembly
NRZ32_03200	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NRZ32_03210	COG1328	CTP reductase activity
NRZ32_03215	COG0602	queuosine metabolic process
NRZ32_03245	COG1566	PFAM secretion protein HlyD family protein
NRZ32_03250	COG1846	Transcriptional regulator
NRZ32_03265	COG0281	malic enzyme
NRZ32_03270	COG3290	protein histidine kinase activity
NRZ32_03275	COG4565	transcriptional regulatory protein
NRZ32_03280	COG0697	spore germination
NRZ32_03295	COG3284	Transcriptional regulator
NRZ32_03300	COG1960	acyl-CoA dehydrogenase activity
NRZ32_03305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NRZ32_03310	COG0346	lactoylglutathione lyase activity
NRZ32_03315	COG0745	RESPONSE REGULATOR receiver
NRZ32_03320	COG5002	protein histidine kinase activity
NRZ32_03360	COG0545	Peptidyl-prolyl cis-trans isomerase
NRZ32_03365	COG1131	(ABC) transporter
NRZ32_03380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ32_03385	COG4597	amino acid ABC transporter
NRZ32_03390	COG0765	amino acid transport
NRZ32_03395	COG1126	abc transporter atp-binding protein
NRZ32_03405	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
NRZ32_03415	COG0678	peroxiredoxin activity
NRZ32_03425	COG0019	diaminopimelate decarboxylase activity
NRZ32_03430	COG1115	amino acid carrier protein
NRZ32_03435	COG0095	Lipoate-protein ligase
NRZ32_03440	COG2233	PERMEase
NRZ32_03455	COG0534	Mate efflux family protein
NRZ32_03460	COG2207	Transcriptional regulator
NRZ32_03465	COG0281	malic enzyme
NRZ32_03495	COG0733	neurotransmitter:sodium symporter activity
NRZ32_03500	COG1752	Esterase of the alpha-beta hydrolase superfamily
NRZ32_03510	COG1566	PFAM secretion protein HlyD family protein
NRZ32_03515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRZ32_03525	COG1032	radical SAM domain protein
NRZ32_03550	COG3152	Membrane
NRZ32_03575	COG0673	inositol 2-dehydrogenase activity
NRZ32_03580	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NRZ32_03585	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NRZ32_03590	COG0739	heme binding
NRZ32_03590	COG0741	lytic transglycosylase activity
NRZ32_03590	COG1196	nuclear chromosome segregation
NRZ32_03595	COG0366	Alpha amylase catalytic
NRZ32_03615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRZ32_03625	COG0788	formyltetrahydrofolate deformylase activity
NRZ32_03630	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NRZ32_03640	COG3118	belongs to the thioredoxin family
NRZ32_03650	COG0791	NLP P60 protein
NRZ32_03655	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
NRZ32_03670	COG1376	ErfK ybiS ycfS ynhG family protein
NRZ32_03670	COG1388	LysM domain
NRZ32_03690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRZ32_03695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRZ32_03700	COG0745	RESPONSE REGULATOR receiver
NRZ32_03705	COG5002	protein histidine kinase activity
NRZ32_03720	COG0583	DNA-binding transcription factor activity
NRZ32_03725	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NRZ32_03730	COG0243	molybdopterin cofactor binding
NRZ32_03740	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NRZ32_03750	COG1960	acyl-CoA dehydrogenase activity
NRZ32_03765	COG0469	pyruvate kinase activity
NRZ32_03770	COG1737	Transcriptional regulator
NRZ32_03790	COG2274	protein secretion by the type I secretion system
NRZ32_03800	COG2274	protein secretion by the type I secretion system
NRZ32_03810	COG2994	toxin metabolic process
NRZ32_03815	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
NRZ32_03815	COG1073	alpha beta
NRZ32_03815	COG3064	Membrane
NRZ32_03820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NRZ32_03835	COG1342	Belongs to the UPF0251 family
NRZ32_03840	COG0640	Transcriptional regulator
NRZ32_03855	COG0798	PFAM Bile acid sodium symporter
NRZ32_03860	COG1393	Belongs to the ArsC family
NRZ32_03875	COG1677	Flagellar hook-basal body complex protein FliE
NRZ32_03885	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NRZ32_03940	COG1684	flagellar biosynthetic protein fliR
NRZ32_03950	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NRZ32_03975	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
NRZ32_03980	COG0643	Histidine kinase
NRZ32_03980	COG0784	Response regulator, receiver
NRZ32_03980	COG2198	Histidine kinase
NRZ32_03985	COG2201	protein-glutamate methylesterase activity
NRZ32_03990	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NRZ32_04000	COG1192	Involved in chromosome partitioning
NRZ32_04010	COG0835	chemotaxis
NRZ32_04025	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NRZ32_04030	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NRZ32_04035	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NRZ32_04040	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
NRZ32_04045	COG1138	Cytochrome C-type biogenesis protein
NRZ32_04050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NRZ32_04055	COG3088	subunit of a heme lyase
NRZ32_04055	COG4235	cytochrome complex assembly
NRZ32_04075	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NRZ32_04080	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NRZ32_04080	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NRZ32_04095	COG0259	pyridoxamine-phosphate oxidase activity
NRZ32_04100	COG0625	glutathione transferase activity
NRZ32_04110	COG3153	acetyltransferase
NRZ32_04130	COG2850	peptidyl-arginine hydroxylation
NRZ32_04135	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NRZ32_04140	COG2915	High frequency lysogenization protein hflD homolog
NRZ32_04145	COG0482	sulfurtransferase activity
NRZ32_04155	COG1187	pseudouridine synthase activity
NRZ32_04165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ32_04165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRZ32_04165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRZ32_04175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ32_04175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRZ32_04175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRZ32_04190	COG0456	acetyltransferase
NRZ32_04200	COG0789	Transcriptional regulator
NRZ32_04205	COG1902	pentaerythritol trinitrate reductase activity
NRZ32_04205	COG0446	pyridine nucleotide-disulphide oxidoreductase
NRZ32_04210	COG1609	Transcriptional regulator
NRZ32_04215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ32_04215	COG1263	PTS System
NRZ32_04220	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NRZ32_04235	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRZ32_04255	COG2207	Transcriptional regulator
NRZ32_04260	COG0538	isocitrate dehydrogenase activity
NRZ32_04265	COG0659	secondary active sulfate transmembrane transporter activity
NRZ32_04275	COG3048	D-serine ammonia-lyase activity
NRZ32_04280	COG0583	DNA-binding transcription factor activity
NRZ32_04310	COG0419	ATPase involved in DNA repair
NRZ32_04325	COG1104	cysteine desulfurase activity
NRZ32_04465	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NRZ32_04470	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NRZ32_04480	COG2135	peptidase activity
NRZ32_04520	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NRZ32_04525	COG2867	negative regulation of translational initiation
NRZ32_04530	COG2914	Belongs to the UPF0125 (RnfH) family
NRZ32_04535	COG0702	epimerase
NRZ32_04540	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NRZ32_04545	COG1454	alcohol dehydrogenase
NRZ32_04555	COG0564	pseudouridine synthase activity
NRZ32_04585	COG1280	lysine exporter protein (LysE YggA)
NRZ32_04615	COG3263	regulation of cellular component size
NRZ32_04625	COG1876	peptidase activity
NRZ32_04630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NRZ32_04635	COG1393	Belongs to the ArsC family
NRZ32_04650	COG0583	DNA-binding transcription factor activity
NRZ32_04660	COG3069	C4-dicarboxylate transmembrane transporter activity
NRZ32_04675	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NRZ32_04680	COG0017	Asparaginyl-tRNA synthetase
NRZ32_04700	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NRZ32_04705	COG0156	8-amino-7-oxononanoate synthase activity
NRZ32_04710	COG2226	methyltransferase
NRZ32_04710	COG1073	alpha beta
NRZ32_04715	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NRZ32_04720	COG0501	Belongs to the peptidase M48B family
NRZ32_04730	COG0633	Ferredoxin
NRZ32_04730	COG3217	Mosc domain protein beta barrel domain protein
NRZ32_04730	COG0633	Ferredoxin
NRZ32_04730	COG3217	Mosc domain protein beta barrel domain protein
NRZ32_04740	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NRZ32_04740	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NRZ32_04740	COG0674	pyruvate-flavodoxin oxidoreductase activity
NRZ32_04740	COG1013	pyruvate-flavodoxin oxidoreductase activity
NRZ32_04745	COG2366	antibiotic biosynthetic process
NRZ32_04750	COG1917	Cupin 2, conserved barrel domain protein
NRZ32_04750	COG2169	Transcriptional regulator
NRZ32_04755	COG2841	Protein conserved in bacteria
NRZ32_04765	COG0534	Mate efflux family protein
NRZ32_04805	COG1309	transcriptional regulator
NRZ32_04820	COG0791	NLP P60 protein
NRZ32_04830	COG0583	DNA-binding transcription factor activity
NRZ32_04835	COG0450	alkyl hydroperoxide reductase
NRZ32_04855	COG0500	methyltransferase
NRZ32_04860	COG4106	trans-aconitate 2-methyltransferase activity
NRZ32_04865	COG1801	Protein of unknown function DUF72
NRZ32_04870	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NRZ32_04875	COG0217	transcriptional regulatory protein
NRZ32_04880	COG2194	sulfuric ester hydrolase activity
NRZ32_04885	COG1940	carbohydrate kinase activity
NRZ32_04885	COG1846	Transcriptional regulator
NRZ32_04890	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NRZ32_04895	COG0363	glucosamine-6-phosphate deaminase activity
NRZ32_04900	COG1263	PTS System
NRZ32_04900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ32_04900	COG2190	(PTS) system
NRZ32_04910	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NRZ32_04915	COG0735	belongs to the Fur family
NRZ32_04925	COG0716	FMN binding
NRZ32_04940	COG0596	Alpha beta hydrolase
NRZ32_04945	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
NRZ32_04950	COG0033	Phosphoglucomutase
NRZ32_04960	COG1846	Transcriptional regulator
NRZ32_04975	COG2951	lytic endotransglycosylase activity
NRZ32_04980	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NRZ32_04985	COG4136	ATPase activity
NRZ32_04995	COG4134	Bacterial extracellular solute-binding protein
NRZ32_05005	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NRZ32_05015	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NRZ32_05020	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NRZ32_05030	COG0729	surface antigen
NRZ32_05035	COG2911	Protein conserved in bacteria
NRZ32_05055	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NRZ32_05065	COG0741	lytic transglycosylase activity
NRZ32_05080	COG1607	acyl-coa hydrolase
NRZ32_05090	COG3021	interspecies interaction between organisms
NRZ32_05095	COG0741	lytic transglycosylase activity
NRZ32_05095	COG1388	LysM domain
NRZ32_05100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ32_05105	COG2226	methyltransferase
NRZ32_05110	COG0328	RNA-DNA hybrid ribonuclease activity
NRZ32_05115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NRZ32_05125	COG0784	Response regulator, receiver
NRZ32_05125	COG3437	response regulator, receiver
NRZ32_05130	COG1960	acyl-CoA dehydrogenase activity
NRZ32_05135	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NRZ32_05140	COG0121	glutamine amidotransferase
NRZ32_05170	COG2197	response regulator
NRZ32_05175	COG3850	Histidine kinase
NRZ32_05180	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NRZ32_05185	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NRZ32_05185	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
NRZ32_05195	COG0243	molybdopterin cofactor binding
NRZ32_05200	COG0437	4 iron, 4 sulfur cluster binding
NRZ32_05205	COG0348	domain, Protein
NRZ32_05215	COG3005	denitrification pathway
NRZ32_05220	COG0521	Mo-molybdopterin cofactor biosynthetic process
NRZ32_05225	COG0315	cyclic pyranopterin monophosphate synthase activity
NRZ32_05230	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NRZ32_05235	COG0314	molybdopterin synthase activity
NRZ32_05250	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NRZ32_05255	COG2267	carboxylic ester hydrolase activity
NRZ32_05280	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NRZ32_05290	COG0302	gtp cyclohydrolase
NRZ32_05295	COG0840	transmembrane signaling receptor activity
NRZ32_05300	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NRZ32_05310	COG0583	DNA-binding transcription factor activity
NRZ32_05340	COG2195	Cleaves the N-terminal amino acid of tripeptides
NRZ32_05350	COG1166	arginine decarboxylase activity
NRZ32_05360	COG2015	COG2015, Alkyl sulfatase and related hydrolases
NRZ32_05365	COG0583	DNA-binding transcription factor activity
NRZ32_05385	COG0814	amino acid
NRZ32_05395	COG3681	Belongs to the UPF0597 family
NRZ32_05400	COG2964	Protein conserved in bacteria
NRZ32_05410	COG1061	Type III restriction enzyme res subunit
NRZ32_05420	COG0346	lactoylglutathione lyase activity
NRZ32_05430	COG1187	pseudouridine synthase activity
NRZ32_05440	COG2807	transmembrane transport
NRZ32_05450	COG0583	DNA-binding transcription factor activity
NRZ32_05455	COG2271	Major facilitator Superfamily
NRZ32_05485	COG2979	Protein of unknown function (DUF533)
NRZ32_05495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRZ32_05505	COG1294	oxidase, subunit
NRZ32_05525	COG3220	belongs to the UPF0276 family
NRZ32_05540	COG2814	Major facilitator Superfamily
NRZ32_05545	COG0656	L-ascorbic acid biosynthetic process
NRZ32_05570	COG0583	DNA-binding transcription factor activity
NRZ32_05580	COG0840	transmembrane signaling receptor activity
NRZ32_05585	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NRZ32_05590	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NRZ32_05595	COG2271	Major facilitator Superfamily
NRZ32_05600	COG1349	DNA-binding transcription factor activity
NRZ32_05615	COG0584	glycerophosphoryl diester phosphodiesterase
NRZ32_05620	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NRZ32_05625	COG0287	Prephenate dehydrogenase
NRZ32_05625	COG1605	Chorismate mutase
NRZ32_05630	COG0583	DNA-binding transcription factor activity
NRZ32_05635	COG3085	chromosome segregation
NRZ32_05640	COG4574	serine-type endopeptidase inhibitor activity
NRZ32_05660	COG1770	oligopeptidase
NRZ32_05665	COG4771	TonB-dependent receptor
NRZ32_05670	COG3083	sulfuric ester hydrolase activity
NRZ32_05675	COG3082	Protein of unknown function (DUF1414)
NRZ32_05680	COG3081	Nucleoid-associated protein
NRZ32_05690	COG1175	transmembrane transport
NRZ32_05695	COG3833	ABC-type maltose transport systems, permease component
NRZ32_05700	COG3842	ATPase activity
NRZ32_05710	COG0596	Alpha beta hydrolase
NRZ32_05725	COG0425	Belongs to the sulfur carrier protein TusA family
NRZ32_05730	COG4783	chaperone-mediated protein folding
NRZ32_05740	COG1393	Belongs to the ArsC family
NRZ32_05760	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NRZ32_05765	COG2431	L-lysine efflux transmembrane transporter activity
NRZ32_05775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ32_05795	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NRZ32_05805	COG0446	pyridine nucleotide-disulphide oxidoreductase
NRZ32_05810	COG2373	Large extracellular alpha-helical protein
NRZ32_05815	COG4953	penicillin-binding protein 1C
NRZ32_05825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRZ32_05825	COG0301	tRNA thio-modification
NRZ32_05840	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NRZ32_05845	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NRZ32_05885	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NRZ32_05905	COG0483	inositol monophosphate 1-phosphatase activity
NRZ32_05915	COG0625	glutathione transferase activity
NRZ32_05920	COG2814	Major facilitator Superfamily
NRZ32_05940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NRZ32_05945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NRZ32_05950	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NRZ32_05955	COG0509	glycine decarboxylation via glycine cleavage system
NRZ32_05960	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NRZ32_05960	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NRZ32_05965	COG0641	radical SAM
NRZ32_05970	COG3119	arylsulfatase activity
NRZ32_05985	COG3852	Histidine kinase
NRZ32_05990	COG0477	Major facilitator Superfamily
NRZ32_05995	COG3634	alkyl hydroperoxide reductase activity
NRZ32_06005	COG0517	IMP dehydrogenase activity
NRZ32_06010	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NRZ32_06015	COG0343	queuine tRNA-ribosyltransferase activity
NRZ32_06020	COG1862	Preprotein translocase
NRZ32_06025	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NRZ32_06030	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NRZ32_06045	COG0826	peptidase U32
NRZ32_06050	COG0826	peptidase U32
NRZ32_06055	COG3154	lipid carrier protein
NRZ32_06075	COG1104	cysteine desulfurase activity
NRZ32_06080	COG0822	iron-sulfur transferase activity
NRZ32_06090	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NRZ32_06095	COG0443	Heat shock 70 kDa protein
NRZ32_06100	COG0633	Ferredoxin
NRZ32_06110	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NRZ32_06115	COG0105	UTP biosynthetic process
NRZ32_06120	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NRZ32_06135	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NRZ32_06140	COG0124	histidyl-tRNA synthetase
NRZ32_06145	COG2976	Protein conserved in bacteria
NRZ32_06150	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NRZ32_06155	COG1160	GTP binding
NRZ32_06160	COG1645	bacterial-type flagellum-dependent swarming motility
NRZ32_06165	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NRZ32_06170	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NRZ32_06170	COG0047	phosphoribosylformylglycinamidine synthase activity
NRZ32_06175	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NRZ32_06175	COG2199	diguanylate cyclase activity
NRZ32_06190	COG1007	ATP synthesis coupled electron transport
NRZ32_06195	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRZ32_06205	COG0713	ATP synthesis coupled electron transport
NRZ32_06210	COG0839	Belongs to the complex I subunit 6 family
NRZ32_06215	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRZ32_06220	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NRZ32_06225	COG1034	ATP synthesis coupled electron transport
NRZ32_06240	COG0649	NAD binding
NRZ32_06240	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRZ32_06245	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRZ32_06250	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRZ32_06255	COG1360	Flagellar Motor Protein
NRZ32_06260	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NRZ32_06280	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NRZ32_06300	COG0724	RNA recognition motif
NRZ32_06305	COG4989	oxidoreductase activity
NRZ32_06330	COG3437	response regulator, receiver
NRZ32_06335	COG0583	DNA-binding transcription factor activity
NRZ32_06345	COG5001	Diguanylate cyclase
NRZ32_06345	COG3300	MHYT domain
NRZ32_06350	COG0778	Nitroreductase
NRZ32_06370	COG0583	DNA-binding transcription factor activity
NRZ32_06380	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NRZ32_06385	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NRZ32_06390	COG0539	negative regulation of cytoplasmic translation
NRZ32_06395	COG0776	regulation of translation
NRZ32_06405	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NRZ32_06425	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NRZ32_06430	COG0602	queuosine metabolic process
NRZ32_06435	COG3530	Putative quorum-sensing-regulated virulence factor
NRZ32_06440	COG2096	Adenosyltransferase
NRZ32_06445	COG2916	Histone family protein nucleoid-structuring protein H-NS
NRZ32_06450	COG1757	Na H antiporter
NRZ32_06455	COG1435	thymidine kinase activity
NRZ32_06485	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NRZ32_06490	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
NRZ32_06495	COG0437	4 iron, 4 sulfur cluster binding
NRZ32_06500	COG5557	Pfam Polysulphide reductase, NrfD
NRZ32_06505	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
NRZ32_06510	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NRZ32_06515	COG1773	rubredoxin
NRZ32_06525	COG0601	transmembrane transport
NRZ32_06530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRZ32_06535	COG0444	Belongs to the ABC transporter superfamily
NRZ32_06540	COG3842	ATPase activity
NRZ32_06545	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NRZ32_06555	COG0375	protein maturation
NRZ32_06560	COG0309	Hydrogenase expression formation protein (HypE)
NRZ32_06570	COG0298	carbon dioxide binding
NRZ32_06575	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
NRZ32_06585	COG1921	L-seryl-tRNASec selenium transferase activity
NRZ32_06595	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NRZ32_06605	COG3260	NADH ubiquinone oxidoreductase 20
NRZ32_06610	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRZ32_06615	COG3261	NADH dehydrogenase
NRZ32_06615	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
NRZ32_06620	COG0650	Formate hydrogenlyase subunit 4
NRZ32_06625	COG0651	ATP synthesis coupled electron transport
NRZ32_06630	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
NRZ32_06635	COG3158	transport of potassium into the cell
NRZ32_06650	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
NRZ32_06675	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NRZ32_06680	COG0326	Molecular chaperone. Has ATPase activity
NRZ32_06685	COG0563	adenylate kinase activity
NRZ32_06690	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NRZ32_06695	COG3788	relative of glutathione S-transferase, MAPEG superfamily
NRZ32_06700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRZ32_06715	COG3300	MHYT domain
NRZ32_06715	COG5001	Diguanylate cyclase
NRZ32_06720	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NRZ32_06740	COG1021	2,3-dihydroxybenzoate-AMP ligase
NRZ32_06745	COG1535	isochorismatase
NRZ32_06745	COG3433	isochorismatase activity
NRZ32_06750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NRZ32_06755	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ32_06765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NRZ32_06770	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NRZ32_06780	COG1120	ATPase activity
NRZ32_06785	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ32_06790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ32_06795	COG4771	TonB-dependent receptor
NRZ32_06835	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NRZ32_06840	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NRZ32_06845	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NRZ32_06860	COG1570	exodeoxyribonuclease VII activity
NRZ32_06865	COG0697	spore germination
NRZ32_06885	COG3158	transport of potassium into the cell
NRZ32_06890	COG0517	IMP dehydrogenase activity
NRZ32_06890	COG0516	GMP reductase activity
NRZ32_06895	COG0519	Catalyzes the synthesis of GMP from XMP
NRZ32_06895	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NRZ32_06935	COG2062	phosphohistidine phosphatase, SixA
NRZ32_06945	COG0697	spore germination
NRZ32_06950	COG4166	transmembrane transport
NRZ32_06955	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
NRZ32_06960	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NRZ32_06970	COG4591	ABC-type transport system involved in lipoprotein release permease component
NRZ32_06975	COG1136	(ABC) transporter
NRZ32_06980	COG4591	ABC-type transport system involved in lipoprotein release permease component
NRZ32_06985	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
NRZ32_06995	COG0544	peptidyl-prolyl cis-trans isomerase activity
NRZ32_07000	COG0740	serine-type endopeptidase activity
NRZ32_07005	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NRZ32_07010	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NRZ32_07015	COG0776	regulation of translation
NRZ32_07020	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NRZ32_07025	COG0488	(ABC) transporter
NRZ32_07030	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NRZ32_07035	COG3162	membrane
NRZ32_07050	COG1024	Enoyl-CoA hydratase
NRZ32_07085	COG1115	amino acid carrier protein
NRZ32_07100	COG1584	GPR1 FUN34 yaaH family protein
NRZ32_07135	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NRZ32_07140	COG1960	acyl-CoA dehydrogenase activity
NRZ32_07150	COG1960	acyl-CoA dehydrogenase activity
NRZ32_07155	COG1024	Enoyl-CoA hydratase
NRZ32_07160	COG1024	Enoyl-CoA hydratase
NRZ32_07170	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ32_07180	COG0730	response to heat
NRZ32_07195	COG1073	alpha beta
NRZ32_07200	COG1506	peptidase
NRZ32_07200	COG0823	Involved in the tonB-independent uptake of proteins
NRZ32_07205	COG0702	epimerase
NRZ32_07215	COG0667	Aldo Keto reductase
NRZ32_07235	COG0583	DNA-binding transcription factor activity
NRZ32_07240	COG2723	6-phospho-beta-galactosidase activity
NRZ32_07245	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NRZ32_07255	COG0583	DNA-binding transcription factor activity
NRZ32_07260	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NRZ32_07265	COG0673	inositol 2-dehydrogenase activity
NRZ32_07270	COG0583	DNA-binding transcription factor activity
NRZ32_07280	COG1560	Kdo2-lipid A biosynthetic process
NRZ32_07285	COG1560	Kdo2-lipid A biosynthetic process
NRZ32_07300	COG2199	diguanylate cyclase activity
NRZ32_07300	COG2203	Gaf domain
NRZ32_07310	COG0417	DNA replication proofreading
NRZ32_07340	COG0534	Mate efflux family protein
NRZ32_07350	COG0307	riboflavin synthase, alpha
NRZ32_07360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRZ32_07365	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NRZ32_07370	COG0697	spore germination
NRZ32_07375	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NRZ32_07420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NRZ32_07425	COG3099	Belongs to the UPF0263 family
NRZ32_07430	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NRZ32_07435	COG2894	cell division
NRZ32_07440	COG0850	regulation of cytokinetic process
NRZ32_07445	COG3100	YcgL domain-containing protein
NRZ32_07450	COG2951	lytic endotransglycosylase activity
NRZ32_07455	COG1760	l-serine dehydratase
NRZ32_07460	COG1760	l-serine dehydratase
NRZ32_07465	COG3123	guanosine phosphorylase activity
NRZ32_07485	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
NRZ32_07490	COG2067	long-chain fatty acid transport protein
NRZ32_07505	COG1595	DNA-templated transcription, initiation
NRZ32_07535	COG0714	Associated with various cellular activities
NRZ32_07540	COG0183	Belongs to the thiolase family
NRZ32_07545	COG1250	3-hydroxyacyl-CoA dehydrogenase
NRZ32_07545	COG1024	Enoyl-CoA hydratase
NRZ32_07575	COG3829	transcription factor binding
NRZ32_07580	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NRZ32_07585	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NRZ32_07590	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NRZ32_07600	COG0549	Belongs to the carbamate kinase family
NRZ32_07605	COG0697	spore germination
NRZ32_07610	COG3608	succinylglutamate desuccinylase aspartoacylase
NRZ32_07610	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NRZ32_07615	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NRZ32_07620	COG2068	MobA-Related Protein
NRZ32_07650	COG0493	'glutamate synthase
NRZ32_07650	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NRZ32_07655	COG0402	S-adenosylhomocysteine deaminase activity
NRZ32_07660	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NRZ32_07665	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NRZ32_07665	COG2080	2 iron, 2 sulfur cluster binding
NRZ32_07670	COG2233	PERMEase
NRZ32_07675	COG0402	S-adenosylhomocysteine deaminase activity
NRZ32_07680	COG2252	PERMEase
NRZ32_07685	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NRZ32_07690	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NRZ32_07695	COG2080	2 iron, 2 sulfur cluster binding
NRZ32_07705	COG3134	Outer membrane lipoprotein
NRZ32_07715	COG1288	antiporter activity
NRZ32_07720	COG0318	PFAM AMP-dependent synthetase and ligase
NRZ32_07725	COG2378	regulation of single-species biofilm formation
NRZ32_07735	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NRZ32_07735	COG0140	phosphoribosyl-ATP diphosphatase activity
NRZ32_07740	COG0107	imidazoleglycerol-phosphate synthase activity
NRZ32_07745	COG0784	Response regulator, receiver
NRZ32_07745	COG2198	Histidine kinase
NRZ32_07745	COG2205	protein histidine kinase activity
NRZ32_07750	COG2199	diguanylate cyclase activity
NRZ32_07755	COG3437	response regulator, receiver
NRZ32_07760	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NRZ32_07765	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NRZ32_07770	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NRZ32_07770	COG0131	Imidazoleglycerol-phosphate dehydratase
NRZ32_07775	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NRZ32_07780	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NRZ32_07785	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NRZ32_07795	COG1199	ATP-dependent helicase activity
NRZ32_07800	COG1214	PFAM Peptidase M22, glycoprotease
NRZ32_07810	COG2267	carboxylic ester hydrolase activity
NRZ32_07815	COG0318	PFAM AMP-dependent synthetase and ligase
NRZ32_07820	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
NRZ32_07835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NRZ32_07840	COG2832	Protein of unknown function (DUF454)
NRZ32_07845	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NRZ32_07855	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NRZ32_07860	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NRZ32_07870	COG3314	Sporulation integral membrane protein YlbJ
NRZ32_07880	COG0517	IMP dehydrogenase activity
NRZ32_07880	COG0617	tRNA 3'-terminal CCA addition
NRZ32_07880	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NRZ32_07885	COG1643	Atp-dependent helicase
NRZ32_07895	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NRZ32_07905	COG3437	response regulator, receiver
NRZ32_07910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ32_07915	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
NRZ32_07920	COG0709	Synthesizes selenophosphate from selenide and ATP
NRZ32_07935	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NRZ32_07940	COG0840	transmembrane signaling receptor activity
NRZ32_07945	COG1254	Belongs to the acylphosphatase family
NRZ32_07950	COG0625	glutathione transferase activity
NRZ32_07955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRZ32_07955	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRZ32_07960	COG0489	protein tyrosine kinase activity
NRZ32_07965	COG0572	uridine kinase
NRZ32_07970	COG0717	Belongs to the dCTP deaminase family
NRZ32_07975	COG0306	phosphate transporter
NRZ32_07980	COG1530	ribonuclease E activity
NRZ32_07990	COG0546	phosphoglycolate phosphatase activity
NRZ32_07995	COG0424	maF-like protein
NRZ32_08005	COG1399	metal-binding, possibly nucleic acid-binding protein
NRZ32_08010	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NRZ32_08015	COG0416	fatty acid biosynthetic process
NRZ32_08020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NRZ32_08030	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ32_08035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NRZ32_08045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NRZ32_08050	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NRZ32_08055	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NRZ32_08060	COG0470	DNA polymerase III
NRZ32_08065	COG0084	hydrolase, TatD family'
NRZ32_08080	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
NRZ32_08080	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NRZ32_08085	COG3008	intermembrane lipid transfer
NRZ32_08090	COG2995	paraquat-inducible protein a
NRZ32_08100	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NRZ32_08105	COG0372	Belongs to the citrate synthase family
NRZ32_08150	COG4221	oxidoreductase activity
NRZ32_08160	COG3141	response to X-ray
NRZ32_08230	COG1067	ATP-dependent peptidase activity
NRZ32_08235	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NRZ32_08250	COG0488	(ABC) transporter
NRZ32_08260	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NRZ32_08260	COG0116	Belongs to the methyltransferase superfamily
NRZ32_08270	COG0167	dihydroorotate dehydrogenase activity
NRZ32_08275	COG2902	Dehydrogenase
NRZ32_08285	COG0308	aminopeptidase N
NRZ32_08295	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
NRZ32_08300	COG1956	GAF domain-containing protein
NRZ32_08310	COG3278	Belongs to the heme-copper respiratory oxidase family
NRZ32_08325	COG2010	Cytochrome c
NRZ32_08350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NRZ32_08355	COG0589	response to stress
NRZ32_08360	COG0037	tRNA processing
NRZ32_08380	COG1869	D-ribose catabolic process
NRZ32_08385	COG1129	ABC transporter
NRZ32_08390	COG1172	Belongs to the binding-protein-dependent transport system permease family
NRZ32_08395	COG1879	ABC-type sugar transport system periplasmic component
NRZ32_08400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRZ32_08405	COG1609	Transcriptional regulator
NRZ32_08410	COG2199	diguanylate cyclase activity
NRZ32_08435	COG0784	Response regulator, receiver
NRZ32_08435	COG2205	protein histidine kinase activity
NRZ32_08440	COG0776	regulation of translation
NRZ32_08445	COG0072	phenylalanine-tRNA ligase activity
NRZ32_08445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRZ32_08450	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NRZ32_08455	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NRZ32_08460	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NRZ32_08465	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NRZ32_08470	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NRZ32_08495	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NRZ32_08505	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NRZ32_08515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NRZ32_08520	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
NRZ32_08525	COG3313	Fe-S protein
NRZ32_08530	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRZ32_08530	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
NRZ32_08530	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRZ32_08535	COG1105	Belongs to the carbohydrate kinase PfkB family
NRZ32_08540	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ32_08540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ32_08545	COG1609	Transcriptional regulator
NRZ32_08550	COG0814	amino acid
NRZ32_08565	COG0513	Belongs to the DEAD box helicase family
NRZ32_08575	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NRZ32_08580	COG2890	protein-(glutamine-N5) methyltransferase activity
NRZ32_08585	COG2840	Smr protein MutS2
NRZ32_08595	COG3706	GGDEF domain
NRZ32_08685	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NRZ32_08690	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
NRZ32_08695	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
NRZ32_08705	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NRZ32_08710	COG1434	Gram-negative-bacterium-type cell wall biogenesis
NRZ32_08720	COG0205	6-phosphofructokinase activity
NRZ32_08725	COG1473	amidohydrolase
NRZ32_08730	COG1011	Hydrolase
NRZ32_08735	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NRZ32_08790	COG3593	DNA synthesis involved in DNA repair
NRZ32_08810	COG0583	DNA-binding transcription factor activity
NRZ32_08815	COG0730	response to heat
NRZ32_08820	COG3148	PFAM DTW domain containing protein
NRZ32_08830	COG1181	Belongs to the D-alanine--D-alanine ligase family
NRZ32_08840	COG0386	Belongs to the glutathione peroxidase family
NRZ32_08845	COG0513	Belongs to the DEAD box helicase family
NRZ32_08885	COG2329	Antibiotic biosynthesis monooxygenase
NRZ32_08890	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NRZ32_08920	COG2501	S4 domain
NRZ32_08930	COG1132	(ABC) transporter
NRZ32_08935	COG1132	(ABC) transporter
NRZ32_08945	COG3118	belongs to the thioredoxin family
NRZ32_08950	COG0471	metal ion transport
NRZ32_08955	COG0058	SHG alpha-glucan phosphorylase activity
NRZ32_08985	COG0814	amino acid
NRZ32_08990	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NRZ32_08995	COG0514	ATP-dependent DNA helicase (RecQ)
NRZ32_09000	COG2766	serine protein kinase
NRZ32_09005	COG2718	Belongs to the UPF0229 family
NRZ32_09010	COG2719	SpoVR family
NRZ32_09015	COG2186	Transcriptional regulator
NRZ32_09020	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NRZ32_09025	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NRZ32_09030	COG0586	Pfam SNARE associated Golgi protein
NRZ32_09040	COG0556	nucleotide-excision repair
NRZ32_09050	COG2985	domain, Protein
NRZ32_09050	COG0569	domain protein
NRZ32_09055	COG0739	heme binding
NRZ32_09055	COG0741	lytic transglycosylase activity
NRZ32_09055	COG1196	nuclear chromosome segregation
NRZ32_09060	COG3181	Tripartite tricarboxylate transporter family receptor
NRZ32_09075	COG4565	transcriptional regulatory protein
NRZ32_09080	COG3290	protein histidine kinase activity
NRZ32_09085	COG1846	Transcriptional regulator
NRZ32_09085	COG1940	carbohydrate kinase activity
NRZ32_09090	COG0840	transmembrane signaling receptor activity
NRZ32_09095	COG3012	SEC-C Motif Domain Protein
NRZ32_09100	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NRZ32_09105	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
NRZ32_09110	COG0247	lactate metabolic process
NRZ32_09120	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
NRZ32_09125	COG0437	4 iron, 4 sulfur cluster binding
NRZ32_09130	COG3301	Polysulphide reductase, NrfD
NRZ32_09135	COG1138	Cytochrome C-type biogenesis protein
NRZ32_09140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NRZ32_09145	COG3088	subunit of a heme lyase
NRZ32_09145	COG4235	cytochrome complex assembly
NRZ32_09160	COG3033	Beta-eliminating lyase
NRZ32_09170	COG3046	protein related to deoxyribodipyrimidine photolyase
NRZ32_09175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRZ32_09180	COG0517	IMP dehydrogenase activity
NRZ32_09180	COG0516	GMP reductase activity
NRZ32_09195	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NRZ32_09210	COG4774	siderophore transport
NRZ32_09225	COG0583	DNA-binding transcription factor activity
NRZ32_09230	COG2910	NAD(P)H-binding
NRZ32_09245	COG0612	Peptidase, M16
NRZ32_09250	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NRZ32_09255	COG2076	Multidrug Resistance protein
NRZ32_09260	COG1944	ATP diphosphatase activity
NRZ32_09265	COG2116	formate transmembrane transporter activity
NRZ32_09270	COG1882	Formate acetyltransferase
NRZ32_09275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRZ32_09285	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NRZ32_09295	COG1840	ABC-type Fe3 transport system, periplasmic component
NRZ32_09300	COG3842	ATPase activity
NRZ32_09310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRZ32_09315	COG2983	Belongs to the UPF0260 family
NRZ32_09325	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NRZ32_09330	COG0045	succinate-CoA ligase (ADP-forming) activity
NRZ32_09335	COG0508	dehydrogenase complex catalyzes the overall conversion of
NRZ32_09340	COG0567	Dehydrogenase, E1 component
NRZ32_09355	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NRZ32_09380	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NRZ32_09385	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NRZ32_09385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRZ32_09395	COG3069	C4-dicarboxylate transmembrane transporter activity
NRZ32_09410	COG1451	nucleotide metabolic process
NRZ32_09425	COG0254	rRNA binding
NRZ32_09430	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NRZ32_09440	COG0583	DNA-binding transcription factor activity
NRZ32_09445	COG2925	Exonuclease
NRZ32_09455	COG3345	alpha-galactosidase
NRZ32_09460	COG1380	Effector of murein hydrolase LrgA
NRZ32_09465	COG1346	cytolysis
NRZ32_09470	COG0295	cytidine deaminase activity
NRZ32_09475	COG1022	Amp-dependent synthetase and ligase
NRZ32_09490	COG0861	Integral membrane protein TerC family
NRZ32_09495	COG2885	chlorophyll binding
NRZ32_09520	COG2154	pterin-4-alpha-carbinolamine dehydratase
NRZ32_09530	COG3768	UPF0283 membrane protein
NRZ32_09535	COG3106	COG3106 Predicted ATPase
NRZ32_09550	COG1842	Phage shock protein A
NRZ32_09555	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NRZ32_09565	COG4168	peptide transport system, permease
NRZ32_09570	COG4171	peptide transport system, permease
NRZ32_09585	COG4172	Belongs to the ABC transporter superfamily
NRZ32_09595	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NRZ32_09600	COG1286	toxin biosynthetic process
NRZ32_09605	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NRZ32_09610	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NRZ32_09615	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NRZ32_09620	COG1674	ftsk spoiiie
NRZ32_09620	COG0531	amino acid
NRZ32_09630	COG0492	ferredoxin-NADP+ reductase activity
NRZ32_09635	COG3706	GGDEF domain
NRZ32_09640	COG3134	Outer membrane lipoprotein
NRZ32_09645	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NRZ32_09650	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NRZ32_09655	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NRZ32_09660	COG0542	response to heat
NRZ32_09665	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NRZ32_09670	COG1278	Cold shock
NRZ32_09675	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NRZ32_09705	COG3266	domain, Protein
NRZ32_09705	COG4193	domain, Protein
NRZ32_09705	COG5632	N-Acetylmuramoyl-L-alanine amidase
NRZ32_09740	COG3829	transcription factor binding
NRZ32_09810	COG3209	COG3209 Rhs family protein
NRZ32_09835	COG0659	secondary active sulfate transmembrane transporter activity
NRZ32_09875	COG0672	)-iron permease
NRZ32_09895	COG2814	Major facilitator Superfamily
NRZ32_09915	COG1136	(ABC) transporter
NRZ32_09920	COG0577	efflux transmembrane transporter activity
NRZ32_09970	COG1139	Iron-sulfur cluster binding protein
NRZ32_09975	COG0247	lactate metabolic process
NRZ32_09980	COG1620	l-lactate permease
NRZ32_09985	COG0583	DNA-binding transcription factor activity
NRZ32_09990	COG0596	Alpha beta hydrolase
NRZ32_10010	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NRZ32_10015	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NRZ32_10015	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NRZ32_10020	COG0527	aspartate kinase activity
NRZ32_10030	COG1368	sulfuric ester hydrolase activity
NRZ32_10035	COG1619	proteins homologs of microcin C7 resistance protein MccF
NRZ32_10045	COG0393	Putative heavy-metal-binding
NRZ32_10065	COG1252	NADH dehydrogenase
NRZ32_10070	COG3150	esterase
NRZ32_10075	COG2233	PERMEase
NRZ32_10090	COG2354	Protein conserved in bacteria
NRZ32_10110	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NRZ32_10115	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NRZ32_10150	COG0537	adenosine 5'-monophosphoramidase activity
NRZ32_10165	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NRZ32_10180	COG1301	dicarboxylic acid transport
NRZ32_10190	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NRZ32_10195	COG0861	Integral membrane protein TerC family
NRZ32_10205	COG0444	Belongs to the ABC transporter superfamily
NRZ32_10210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRZ32_10215	COG0601	transmembrane transport
NRZ32_10225	COG2095	MarC family integral membrane protein
NRZ32_10235	COG1454	alcohol dehydrogenase
NRZ32_10235	COG1012	belongs to the aldehyde dehydrogenase family
NRZ32_10240	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NRZ32_10240	COG2199	diguanylate cyclase activity
NRZ32_10245	COG3275	phosphorelay sensor kinase activity
NRZ32_10250	COG3279	Response regulator of the LytR AlgR family
NRZ32_10255	COG1966	Carbon starvation protein
NRZ32_10265	COG1566	PFAM secretion protein HlyD family protein
NRZ32_10270	COG1061	Type III restriction enzyme res subunit
NRZ32_10275	COG2027	D-alanyl-D-alanine carboxypeptidase
NRZ32_10280	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NRZ32_10290	COG0436	Aminotransferase
NRZ32_10295	COG3264	Mechanosensitive ion channel
NRZ32_10295	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
NRZ32_10300	COG1288	antiporter activity
NRZ32_10305	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NRZ32_10320	COG0697	spore germination
NRZ32_10325	COG4657	Part of a membrane complex involved in electron transport
NRZ32_10330	COG2878	Part of a membrane complex involved in electron transport
NRZ32_10340	COG4658	electron transport chain
NRZ32_10345	COG4659	FMN binding
NRZ32_10350	COG4660	Part of a membrane complex involved in electron transport
NRZ32_10355	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NRZ32_10360	COG0346	lactoylglutathione lyase activity
NRZ32_10375	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NRZ32_10380	COG2056	Na+-H+ antiporter family
NRZ32_10390	COG2050	protein possibly involved in aromatic compounds catabolism
NRZ32_10400	COG0247	lactate metabolic process
NRZ32_10400	COG0277	FAD linked oxidase domain protein
NRZ32_10410	COG1253	flavin adenine dinucleotide binding
NRZ32_10415	COG1902	pentaerythritol trinitrate reductase activity
NRZ32_10420	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NRZ32_10425	COG0647	UMP catabolic process
NRZ32_10430	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NRZ32_10430	COG4651	solute:proton antiporter activity
NRZ32_10440	COG0367	asparagine synthase
NRZ32_10455	COG0625	glutathione transferase activity
NRZ32_10465	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
NRZ32_10480	COG0564	pseudouridine synthase activity
NRZ32_10485	COG5001	Diguanylate cyclase
NRZ32_10490	COG0840	transmembrane signaling receptor activity
NRZ32_10500	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NRZ32_10500	COG0392	lysyltransferase activity
NRZ32_10505	COG2194	sulfuric ester hydrolase activity
NRZ32_10525	COG0670	Belongs to the BI1 family
NRZ32_10530	COG1289	transmembrane transporter activity
NRZ32_10535	COG2920	part of a sulfur-relay system
NRZ32_10540	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
NRZ32_10545	COG0285	dihydrofolate synthase activity
NRZ32_10550	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NRZ32_10555	COG0101	tRNA pseudouridine synthase activity
NRZ32_10565	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NRZ32_10570	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NRZ32_10575	COG0671	phosphoesterase, PA-phosphatase related
NRZ32_10580	COG1464	Belongs to the NlpA lipoprotein family
NRZ32_10630	COG0574	Belongs to the PEP-utilizing enzyme family
NRZ32_10630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NRZ32_10635	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NRZ32_10705	COG1242	4 iron, 4 sulfur cluster binding
NRZ32_10710	COG0067	glutamate synthase
NRZ32_10710	COG0069	glutamate synthase activity
NRZ32_10710	COG0070	glutamate synthase
NRZ32_10715	COG0493	'glutamate synthase
NRZ32_10730	COG0789	Transcriptional regulator
NRZ32_10745	COG4104	PAAR repeat-containing protein
NRZ32_10755	COG0513	Belongs to the DEAD box helicase family
NRZ32_10760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ32_10790	COG2814	Major facilitator Superfamily
NRZ32_10805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NRZ32_10810	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NRZ32_10815	COG0505	Belongs to the CarA family
NRZ32_10820	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NRZ32_10830	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NRZ32_10835	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NRZ32_10840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NRZ32_10845	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NRZ32_10850	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NRZ32_10855	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
NRZ32_10865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ32_10865	COG2205	protein histidine kinase activity
NRZ32_10905	COG0023	Translation Initiation Factor
NRZ32_10910	COG2119	membrane
NRZ32_10940	COG2199	diguanylate cyclase activity
NRZ32_10940	COG2203	Gaf domain
NRZ32_10945	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NRZ32_10950	COG0210	DNA helicase
NRZ32_10960	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NRZ32_10970	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NRZ32_10975	COG3301	Polysulphide reductase, NrfD
NRZ32_10980	COG0437	4 iron, 4 sulfur cluster binding
NRZ32_10985	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
NRZ32_11040	COG0322	excinuclease ABC activity
NRZ32_11045	COG2197	response regulator
NRZ32_11050	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NRZ32_11055	COG2835	tetraacyldisaccharide 4'-kinase activity
NRZ32_11060	COG1663	tetraacyldisaccharide 4'-kinase activity
NRZ32_11070	COG0658	competence protein
NRZ32_11070	COG2333	competence protein COMEC
NRZ32_11085	COG0433	COG0433 Predicted ATPase
NRZ32_11090	COG1448	Aminotransferase
NRZ32_11105	COG1199	ATP-dependent helicase activity
NRZ32_11115	COG0123	including yeast histone deacetylase and acetoin utilization protein
NRZ32_11120	COG0477	Major facilitator Superfamily
NRZ32_11125	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NRZ32_11150	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NRZ32_11165	COG2271	Major facilitator Superfamily
NRZ32_11170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ32_11175	COG0765	amino acid transport
NRZ32_11195	COG0531	amino acid
NRZ32_11210	COG1253	flavin adenine dinucleotide binding
NRZ32_11225	COG0704	Plays a role in the regulation of phosphate uptake
NRZ32_11230	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NRZ32_11235	COG0581	inorganic phosphate transmembrane transporter activity
NRZ32_11240	COG0573	inorganic phosphate transmembrane transporter activity
NRZ32_11245	COG0590	tRNA wobble adenosine to inosine editing
NRZ32_11260	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NRZ32_11280	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NRZ32_11285	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NRZ32_11290	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NRZ32_11295	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NRZ32_11320	COG2716	regulation of RNA biosynthetic process
NRZ32_11325	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NRZ32_11335	COG2239	Acts as a magnesium transporter
NRZ32_11350	COG3951	Flagellar rod assembly protein muramidase FlgJ
NRZ32_11350	COG1705	Flagellar rod assembly protein muramidase FlgJ
NRZ32_11355	COG1706	bacterial-type flagellum-dependent cell motility
NRZ32_11360	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
NRZ32_11370	COG4787	bacterial-type flagellum-dependent cell motility
NRZ32_11390	COG1815	bacterial-type flagellum-dependent cell motility
NRZ32_11395	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NRZ32_11400	COG0784	Response regulator, receiver
NRZ32_11400	COG0835	chemotaxis
NRZ32_11405	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
NRZ32_11420	COG0622	Phosphoesterase
NRZ32_11425	COG4166	transmembrane transport
NRZ32_11435	COG1187	pseudouridine synthase activity
NRZ32_11450	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NRZ32_11455	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NRZ32_11460	COG1882	Formate acetyltransferase
NRZ32_11465	COG1349	DNA-binding transcription factor activity
NRZ32_11470	COG0697	spore germination
NRZ32_11500	COG1278	Cold shock
NRZ32_11540	COG3132	Protein of unknown function, DUF480
NRZ32_11550	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NRZ32_11585	COG1215	transferase activity, transferring glycosyl groups
NRZ32_11590	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NRZ32_11590	COG0662	Cupin 2, conserved barrel domain protein
NRZ32_11600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NRZ32_11605	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
NRZ32_11625	COG1216	Glycosyl transferase, family 2
NRZ32_11655	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NRZ32_11670	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NRZ32_11670	COG2755	lipolytic protein G-D-S-L family
NRZ32_11695	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NRZ32_11700	COG1091	dTDP-4-dehydrorhamnose reductase activity
NRZ32_11715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRZ32_11720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRZ32_11725	COG1309	transcriptional regulator
NRZ32_11745	COG1946	Acyl-CoA thioesterase
NRZ32_11755	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NRZ32_11765	COG0009	L-threonylcarbamoyladenylate synthase
NRZ32_11775	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NRZ32_11780	COG0512	Glutamine amidotransferase of anthranilate synthase
NRZ32_11780	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NRZ32_11785	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NRZ32_11790	COG0134	indole-3-glycerol-phosphate synthase activity
NRZ32_11790	COG0135	phosphoribosylanthranilate isomerase activity
NRZ32_11795	COG0133	tryptophan synthase activity
NRZ32_11800	COG0159	tryptophan synthase activity
NRZ32_11815	COG1988	membrane-bound metal-dependent
NRZ32_11820	COG1396	sequence-specific DNA binding
NRZ32_11825	COG3550	peptidyl-serine autophosphorylation
NRZ32_11845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRZ32_11855	COG4521	taurine ABC transporter
NRZ32_11860	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NRZ32_11865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NRZ32_11870	COG2175	clavaminate synthase activity
NRZ32_11880	COG2814	Major facilitator Superfamily
NRZ32_11885	COG0109	protoheme IX farnesyltransferase activity
NRZ32_11890	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NRZ32_11895	COG1845	cytochrome c oxidase, subunit III
NRZ32_11900	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NRZ32_11905	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NRZ32_11910	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NRZ32_11960	COG2211	Major facilitator Superfamily
NRZ32_11965	COG0071	Belongs to the small heat shock protein (HSP20) family
NRZ32_11980	COG0708	Exodeoxyribonuclease III
NRZ32_12005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRZ32_12010	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRZ32_12030	COG0095	Lipoate-protein ligase
NRZ32_12060	COG0640	Transcriptional regulator
NRZ32_12075	COG1285	pathogenesis
NRZ32_12105	COG0484	heat shock protein binding
NRZ32_12110	COG0443	Heat shock 70 kDa protein
NRZ32_12115	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NRZ32_12120	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NRZ32_12125	COG0497	DNA recombination
NRZ32_12130	COG1227	inorganic diphosphatase activity
NRZ32_12140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRZ32_12145	COG1136	(ABC) transporter
NRZ32_12145	COG0577	efflux transmembrane transporter activity
NRZ32_12155	COG2375	cellular response to nickel ion
NRZ32_12160	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NRZ32_12185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRZ32_12190	COG1396	sequence-specific DNA binding
NRZ32_12190	COG1917	Cupin 2, conserved barrel domain protein
NRZ32_12210	COG0531	amino acid
NRZ32_12220	COG0531	amino acid
NRZ32_12230	COG1283	sodium-dependent phosphate transmembrane transporter activity
NRZ32_12240	COG3384	dioxygenase
NRZ32_12250	COG0784	Response regulator, receiver
NRZ32_12250	COG2205	protein histidine kinase activity
NRZ32_12250	COG5002	protein histidine kinase activity
NRZ32_12255	COG4251	negative regulation of phosphorylation
NRZ32_12255	COG5001	Diguanylate cyclase
NRZ32_12255	COG3706	GGDEF domain
NRZ32_12255	COG2203	Gaf domain
NRZ32_12260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ32_12260	COG2205	protein histidine kinase activity
NRZ32_12290	COG0488	(ABC) transporter
NRZ32_12305	COG4319	ketosteroid isomerase
NRZ32_12310	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NRZ32_12315	COG0083	homoserine kinase activity
NRZ32_12325	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
NRZ32_12330	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
NRZ32_12345	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NRZ32_12355	COG0745	RESPONSE REGULATOR receiver
NRZ32_12370	COG4988	ABC transporter
NRZ32_12375	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NRZ32_12395	COG1720	tRNA m6t6A37 methyltransferase activity
NRZ32_12400	COG3437	response regulator, receiver
NRZ32_12400	COG2770	Histidine kinase
NRZ32_12415	COG0542	response to heat
NRZ32_12420	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NRZ32_12425	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ32_12430	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NRZ32_12435	COG2190	(PTS) system
NRZ32_12445	COG3038	cytochrome b561
NRZ32_12460	COG0419	ATPase involved in DNA repair
NRZ32_12465	COG0420	3'-5' exonuclease activity
NRZ32_12475	COG2974	May be involved in recombination
NRZ32_12485	COG4651	solute:proton antiporter activity
NRZ32_12485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NRZ32_12500	COG0469	pyruvate kinase activity
NRZ32_12505	COG1196	nuclear chromosome segregation
NRZ32_12505	COG3264	Mechanosensitive ion channel
NRZ32_12515	COG2706	6-phosphogluconolactonase activity
NRZ32_12530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ32_12550	COG0281	malic enzyme
NRZ32_12560	COG0437	4 iron, 4 sulfur cluster binding
NRZ32_12565	COG3383	formate dehydrogenase (NAD+) activity
NRZ32_12565	COG3383	formate dehydrogenase (NAD+) activity
NRZ32_12600	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NRZ32_12610	COG3852	Histidine kinase
NRZ32_12625	COG4662	Binding-protein-dependent transport system inner membrane component
NRZ32_12635	COG0746	molybdenum cofactor guanylyltransferase activity
NRZ32_12640	COG0303	'Molybdopterin
NRZ32_12645	COG1289	transmembrane transporter activity
NRZ32_12650	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NRZ32_12680	COG3220	belongs to the UPF0276 family
NRZ32_12720	COG0784	Response regulator, receiver
NRZ32_12720	COG2205	protein histidine kinase activity
NRZ32_12725	COG4166	transmembrane transport
NRZ32_12730	COG0601	transmembrane transport
NRZ32_12735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRZ32_12740	COG0444	Belongs to the ABC transporter superfamily
NRZ32_12745	COG4608	Belongs to the ABC transporter superfamily
NRZ32_12755	COG2971	BadF BadG BcrA BcrD
NRZ32_12765	COG0840	transmembrane signaling receptor activity
NRZ32_12785	COG3724	N-succinylarginine dihydrolase activity
NRZ32_12790	COG0616	signal peptide processing
NRZ32_12795	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ32_12800	COG0583	DNA-binding transcription factor activity
NRZ32_12810	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NRZ32_12820	COG0583	DNA-binding transcription factor activity
NRZ32_12825	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NRZ32_12830	COG1881	PFAM PEBP family protein
NRZ32_12840	COG3408	Glycogen debranching enzyme
NRZ32_12840	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
NRZ32_12845	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NRZ32_12850	COG0739	heme binding
NRZ32_12855	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NRZ32_12870	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NRZ32_12880	COG3091	SprT-like family
NRZ32_12890	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NRZ32_12895	COG0189	ligase activity
NRZ32_12905	COG1678	Uncharacterized ACR, COG1678
NRZ32_12910	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NRZ32_12915	COG3104	oligopeptide transport
NRZ32_12925	COG0714	Associated with various cellular activities
NRZ32_12940	COG1115	amino acid carrier protein
NRZ32_12945	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NRZ32_12960	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NRZ32_12970	COG1301	dicarboxylic acid transport
NRZ32_12975	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NRZ32_12980	COG2912	Transglutaminase-like superfamily
NRZ32_12990	COG2890	protein-(glutamine-N5) methyltransferase activity
NRZ32_12995	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NRZ32_13000	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NRZ32_13005	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NRZ32_13010	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NRZ32_13020	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NRZ32_13025	COG0737	Belongs to the 5'-nucleotidase family
NRZ32_13030	COG0193	aminoacyl-tRNA hydrolase activity
NRZ32_13035	COG0012	GTP binding
NRZ32_13080	COG0471	metal ion transport
NRZ32_13080	COG0490	domain, Protein
NRZ32_13090	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
NRZ32_13100	COG3097	Belongs to the UPF0267 family
NRZ32_13110	COG0366	Alpha amylase catalytic
NRZ32_13120	COG0488	(ABC) transporter
NRZ32_13150	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRZ32_13150	COG1013	pyruvate-flavodoxin oxidoreductase activity
NRZ32_13150	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NRZ32_13150	COG0674	pyruvate-flavodoxin oxidoreductase activity
NRZ32_13160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRZ32_13170	COG1012	belongs to the aldehyde dehydrogenase family
NRZ32_13180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NRZ32_13195	COG0180	Tryptophanyl-tRNA synthetase
NRZ32_13205	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NRZ32_13210	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NRZ32_13220	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NRZ32_13225	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NRZ32_13255	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NRZ32_13260	COG0583	DNA-binding transcription factor activity
NRZ32_13280	COG0583	DNA-binding transcription factor activity
NRZ32_13295	COG0739	heme binding
NRZ32_13305	COG3264	Mechanosensitive ion channel
NRZ32_13305	COG1511	domain protein
NRZ32_13310	COG0584	glycerophosphoryl diester phosphodiesterase
NRZ32_13320	COG1053	succinate dehydrogenase
NRZ32_13325	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NRZ32_13330	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
NRZ32_13355	COG3214	Protein conserved in bacteria
NRZ32_13395	COG0642	Histidine kinase
NRZ32_13405	COG0516	GMP reductase activity
NRZ32_13415	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NRZ32_13420	COG3647	Membrane
NRZ32_13430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NRZ32_13450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRZ32_13465	COG3706	GGDEF domain
NRZ32_13475	COG1335	isochorismatase
NRZ32_13480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NRZ32_13485	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NRZ32_13490	COG1702	phosphate starvation-inducible protein PhoH
NRZ32_13495	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NRZ32_13500	COG4535	Mg2 and Co2 transporter CorC
NRZ32_13505	COG0815	Transfers the fatty acyl group on membrane lipoproteins
NRZ32_13510	COG2888	peptidyl-tyrosine sulfation
NRZ32_13515	COG0495	leucyl-tRNA aminoacylation
NRZ32_13530	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NRZ32_13535	COG0799	negative regulation of ribosome biogenesis
NRZ32_13540	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NRZ32_13545	COG0768	penicillin binding
NRZ32_13550	COG0772	Belongs to the SEDS family
NRZ32_13555	COG2951	lytic endotransglycosylase activity
NRZ32_13560	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NRZ32_13565	COG1686	Belongs to the peptidase S11 family
NRZ32_13570	COG2921	Belongs to the UPF0250 family
NRZ32_13575	COG0321	lipoyl(octanoyl) transferase activity
NRZ32_13580	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NRZ32_13585	COG3545	Serine hydrolase
NRZ32_13605	COG0789	Transcriptional regulator
NRZ32_13610	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NRZ32_13620	COG1970	mechanosensitive ion channel activity
NRZ32_13630	COG4974	Belongs to the 'phage' integrase family
NRZ32_13640	COG0312	modulator of DNA gyrase
NRZ32_13645	COG0312	modulator of DNA gyrase
NRZ32_13690	COG0114	fumarate hydratase activity
NRZ32_13700	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NRZ32_13705	COG3706	GGDEF domain
NRZ32_13710	COG2211	Major facilitator Superfamily
NRZ32_13715	COG1185	polyribonucleotide nucleotidyltransferase activity
NRZ32_13720	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NRZ32_13725	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NRZ32_13730	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NRZ32_13735	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NRZ32_13740	COG0195	Participates in both transcription termination and antitermination
NRZ32_13745	COG0779	Required for maturation of 30S ribosomal subunits
NRZ32_13760	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NRZ32_13765	COG0149	triose-phosphate isomerase activity
NRZ32_13770	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NRZ32_13775	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NRZ32_13785	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NRZ32_13790	COG1534	Rna-binding protein
NRZ32_13805	COG1360	Flagellar Motor Protein
NRZ32_13810	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NRZ32_13815	COG1722	exodeoxyribonuclease VII activity
NRZ32_13820	COG0142	geranyltranstransferase activity
NRZ32_13825	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NRZ32_13830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRZ32_13835	COG0601	transmembrane transport
NRZ32_13845	COG4172	Belongs to the ABC transporter superfamily
NRZ32_13850	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NRZ32_13855	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NRZ32_13860	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NRZ32_13865	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NRZ32_13880	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NRZ32_13880	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NRZ32_13885	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NRZ32_13900	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NRZ32_13910	COG2205	protein histidine kinase activity
NRZ32_13910	COG2198	Histidine kinase
NRZ32_13910	COG0784	Response regulator, receiver
NRZ32_13915	COG1879	ABC-type sugar transport system periplasmic component
NRZ32_13925	COG0745	RESPONSE REGULATOR receiver
NRZ32_13930	COG3005	denitrification pathway
NRZ32_13940	COG3381	protein complex oligomerization
NRZ32_13960	COG5001	Diguanylate cyclase
NRZ32_13960	COG3300	MHYT domain
NRZ32_13970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NRZ32_13975	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NRZ32_13980	COG0511	ligase activity, forming carbon-carbon bonds
NRZ32_13985	COG0439	Biotin carboxylase
NRZ32_13990	COG3924	membrane
NRZ32_13995	COG4145	pantothenate transmembrane transporter activity
NRZ32_14000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ32_14000	COG1263	PTS System
NRZ32_14000	COG2190	(PTS) system
NRZ32_14005	COG0583	DNA-binding transcription factor activity
NRZ32_14010	COG0604	alcohol dehydrogenase
NRZ32_14015	COG2264	protein methyltransferase activity
NRZ32_14030	COG0778	Nitroreductase
NRZ32_14040	COG1902	pentaerythritol trinitrate reductase activity
NRZ32_14040	COG0446	pyridine nucleotide-disulphide oxidoreductase
NRZ32_14045	COG0616	signal peptide processing
NRZ32_14065	COG3139	Protein of unknown function (DUF1315)
NRZ32_14070	COG0252	asparaginase activity
NRZ32_14075	COG0786	glutamate:sodium symporter activity
NRZ32_14090	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NRZ32_14095	COG0384	phenazine biosynthesis protein PhzF
NRZ32_14100	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NRZ32_14105	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NRZ32_14110	COG0175	sulfate reduction
NRZ32_14115	COG2113	Glycine betaine
NRZ32_14120	COG4176	ABC-type proline glycine betaine transport system permease component
NRZ32_14125	COG4175	Glycine betaine
NRZ32_14135	COG3610	response to peptide
NRZ32_14140	COG2966	Psort location CytoplasmicMembrane, score
NRZ32_14150	COG0521	Mo-molybdopterin cofactor biosynthetic process
NRZ32_14160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NRZ32_14165	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ32_14175	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NRZ32_14200	COG2986	histidine ammonia-lyase
NRZ32_14225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NRZ32_14230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NRZ32_14265	COG1858	cytochrome C peroxidase
NRZ32_14275	COG2313	pseudouridylate synthase activity
NRZ32_14280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRZ32_14305	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NRZ32_14320	COG1073	alpha beta
NRZ32_14325	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
NRZ32_14330	COG2195	Cleaves the N-terminal amino acid of tripeptides
NRZ32_14340	COG0840	transmembrane signaling receptor activity
NRZ32_14365	COG5002	protein histidine kinase activity
NRZ32_14365	COG0784	Response regulator, receiver
NRZ32_14365	COG2198	Histidine kinase
NRZ32_14385	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
NRZ32_14400	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NRZ32_14405	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
NRZ32_14415	COG2716	regulation of RNA biosynthetic process
NRZ32_14420	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NRZ32_14425	COG3013	Belongs to the UPF0304 family
NRZ32_14435	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NRZ32_14440	COG0280	phosphate acetyltransferase
NRZ32_14440	COG0857	belongs to the CobB CobQ family
NRZ32_14445	COG0440	acetolactate synthase activity
NRZ32_14450	COG0028	Belongs to the TPP enzyme family
NRZ32_14465	COG0671	phosphoesterase, PA-phosphatase related
NRZ32_14475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NRZ32_14480	COG0473	3-isopropylmalate dehydrogenase activity
NRZ32_14485	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NRZ32_14490	COG0066	3-isopropylmalate dehydratase activity
NRZ32_14505	COG4143	(ABC) transporter
NRZ32_14515	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
NRZ32_14525	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NRZ32_14565	COG0316	Belongs to the HesB IscA family
NRZ32_14575	COG0038	chloride channel
NRZ32_14580	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NRZ32_14595	COG0671	phosphoesterase, PA-phosphatase related
NRZ32_14605	COG0784	Response regulator, receiver
NRZ32_14605	COG3437	response regulator, receiver
NRZ32_14615	COG2076	Multidrug Resistance protein
NRZ32_14625	COG0346	lactoylglutathione lyase activity
NRZ32_14630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NRZ32_14635	COG1643	Atp-dependent helicase
NRZ32_14645	COG1489	DNA binding
NRZ32_14650	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NRZ32_14655	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NRZ32_14670	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NRZ32_14675	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NRZ32_14695	COG1924	4 iron, 4 sulfur cluster binding
NRZ32_14700	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
NRZ32_14705	COG0842	Transport permease protein
NRZ32_14710	COG1131	(ABC) transporter
NRZ32_14725	COG0163	prenyltransferase activity
NRZ32_14730	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NRZ32_14735	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NRZ32_14750	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
NRZ32_14765	COG1136	(ABC) transporter
NRZ32_14785	COG0840	transmembrane signaling receptor activity
NRZ32_14820	COG0529	Catalyzes the synthesis of activated sulfate
NRZ32_14825	COG0471	metal ion transport
NRZ32_14825	COG3273	potassium ion transport
NRZ32_14830	COG2895	sulfate adenylyltransferase (ATP) activity
NRZ32_14835	COG0175	sulfate reduction
NRZ32_14840	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NRZ32_14840	COG1648	precorrin-2 dehydrogenase activity
NRZ32_14845	COG0330	HflC and HflK could
NRZ32_14850	COG1585	Membrane protein implicated in regulation of membrane protease activity
NRZ32_14855	COG0517	IMP dehydrogenase activity
NRZ32_14855	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NRZ32_14860	COG0488	(ABC) transporter
NRZ32_14870	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NRZ32_14910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NRZ32_14920	COG0668	transmembrane transport
NRZ32_14930	COG2731	YhcH YjgK YiaL family protein
NRZ32_14950	COG1794	racemase activity, acting on amino acids and derivatives
NRZ32_14965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRZ32_14990	COG0733	neurotransmitter:sodium symporter activity
NRZ32_15000	COG0733	neurotransmitter:sodium symporter activity
NRZ32_15015	COG0561	phosphatase activity
NRZ32_15045	COG1846	Transcriptional regulator
NRZ32_15050	COG2130	NADP-dependent
NRZ32_15055	COG1051	belongs to the nudix hydrolase family
NRZ32_15075	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NRZ32_15080	COG1640	4-alpha-glucanotransferase
NRZ32_15085	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NRZ32_15090	COG0676	glucose-6-phosphate 1-epimerase activity
NRZ32_15095	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NRZ32_15100	COG0840	transmembrane signaling receptor activity
NRZ32_15135	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
NRZ32_15140	COG2885	chlorophyll binding
NRZ32_15145	COG0823	Involved in the tonB-independent uptake of proteins
NRZ32_15160	COG0811	peptide transport
NRZ32_15165	COG0824	Thioesterase
NRZ32_15170	COG3790	cyd operon protein YbgE
NRZ32_15175	COG4890	Cyd operon protein YbgT
NRZ32_15180	COG1294	oxidase, subunit
NRZ32_15185	COG1271	oxidase subunit
NRZ32_15190	COG2255	four-way junction helicase activity
NRZ32_15195	COG0632	four-way junction helicase activity
NRZ32_15200	COG0840	transmembrane signaling receptor activity
NRZ32_15205	COG0442	prolyl-tRNA aminoacylation
NRZ32_15210	COG4221	oxidoreductase activity
NRZ32_15225	COG1024	Enoyl-CoA hydratase
NRZ32_15235	COG0110	maltose O-acetyltransferase activity
NRZ32_15245	COG4166	transmembrane transport
NRZ32_15260	COG1872	DUF167
NRZ32_15265	COG0762	integral membrane protein
NRZ32_15270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NRZ32_15275	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NRZ32_15290	COG3022	response to hydroperoxide
NRZ32_15295	COG0513	Belongs to the DEAD box helicase family
NRZ32_15300	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NRZ32_15325	COG0735	belongs to the Fur family
NRZ32_15330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NRZ32_15345	COG0776	regulation of translation
NRZ32_15380	COG0560	Phosphoserine phosphatase
NRZ32_15390	COG3447	MASE1 domain protein
NRZ32_15390	COG5001	Diguanylate cyclase
NRZ32_15390	COG5002	protein histidine kinase activity
NRZ32_15395	COG0813	purine-nucleoside phosphorylase activity
NRZ32_15400	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NRZ32_15405	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NRZ32_15410	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NRZ32_15420	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRZ32_15425	COG0084	hydrolase, TatD family'
NRZ32_15430	COG2165	general secretion pathway protein
NRZ32_15445	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NRZ32_15450	COG0004	ammonium transporteR
NRZ32_15465	COG0795	lipopolysaccharide-transporting ATPase activity
NRZ32_15470	COG0795	lipopolysaccharide-transporting ATPase activity
NRZ32_15475	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NRZ32_15480	COG2927	DNA polymerase III (CHI subunit)
NRZ32_15485	COG0525	valine-tRNA ligase activity
NRZ32_15490	COG1253	flavin adenine dinucleotide binding
NRZ32_15495	COG0586	Pfam SNARE associated Golgi protein
NRZ32_15500	COG1686	Belongs to the peptidase S11 family
NRZ32_15530	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NRZ32_15535	COG0527	aspartate kinase activity
NRZ32_15540	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NRZ32_15550	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NRZ32_15555	COG1546	Belongs to the CinA family
NRZ32_15560	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NRZ32_15580	COG3068	Protein conserved in bacteria
NRZ32_15590	COG0739	heme binding
NRZ32_15610	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
NRZ32_15615	COG1121	(ABC) transporter
NRZ32_15620	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NRZ32_15625	COG0583	DNA-binding transcription factor activity
NRZ32_15630	COG0697	spore germination
NRZ32_15635	COG1573	uracil-dna glycosylase
NRZ32_15640	COG2962	Rard protein
NRZ32_15650	COG2827	Endonuclease containing a URI domain
NRZ32_15665	COG1842	Phage shock protein A
NRZ32_15670	COG0204	Acyl-transferase
NRZ32_15690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NRZ32_15740	COG0583	DNA-binding transcription factor activity
NRZ32_15750	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NRZ32_15760	COG0583	DNA-binding transcription factor activity
NRZ32_15780	COG1289	transmembrane transporter activity
NRZ32_15785	COG1566	PFAM secretion protein HlyD family protein
NRZ32_15800	COG1051	belongs to the nudix hydrolase family
NRZ32_15805	COG3150	esterase
NRZ32_15815	COG3151	Protein conserved in bacteria
NRZ32_15820	COG0494	nUDIX hydrolase
NRZ32_15825	COG1538	Outer membrane efflux protein
NRZ32_15830	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NRZ32_15830	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NRZ32_15835	COG1560	Kdo2-lipid A biosynthetic process
NRZ32_15850	COG1392	Phosphate transport regulator
NRZ32_15855	COG0306	phosphate transporter
NRZ32_15860	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NRZ32_15890	COG0583	DNA-binding transcription factor activity
NRZ32_15895	COG1380	Effector of murein hydrolase LrgA
NRZ32_15900	COG1346	cytolysis
NRZ32_15915	COG0617	tRNA 3'-terminal CCA addition
NRZ32_15920	COG3409	Peptidoglycan-binding domain 1 protein
NRZ32_15920	COG3267	Type II secretory pathway component ExeA
NRZ32_15930	COG1194	a g-specific adenine glycosylase
NRZ32_15935	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
NRZ32_15945	COG3111	PFAM Bacterial OB fold (BOF) protein
NRZ32_15950	COG3240	lipase activity
NRZ32_15965	COG3009	Protein conserved in bacteria
NRZ32_15970	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NRZ32_15970	COG3008	intermembrane lipid transfer
NRZ32_15975	COG2995	paraquat-inducible protein a
NRZ32_15985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRZ32_15995	COG2203	Gaf domain
NRZ32_15995	COG5001	Diguanylate cyclase
NRZ32_15995	COG4251	negative regulation of phosphorylation
NRZ32_15995	COG3706	GGDEF domain
NRZ32_16000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NRZ32_16005	COG2813	Specifically methylates the guanine in position
NRZ32_16010	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NRZ32_16015	COG0297	glycogen (starch) synthase activity
NRZ32_16045	COG1757	Na H antiporter
NRZ32_16050	COG0583	DNA-binding transcription factor activity
NRZ32_16055	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NRZ32_16060	COG3842	ATPase activity
NRZ32_16065	COG1176	ABC-type spermidine putrescine transport system, permease component I
NRZ32_16070	COG1177	transmembrane transport
NRZ32_16075	COG1012	belongs to the aldehyde dehydrogenase family
NRZ32_16100	COG0110	maltose O-acetyltransferase activity
NRZ32_16105	COG0366	Alpha amylase catalytic
NRZ32_16110	COG1263	PTS System
NRZ32_16110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ32_16130	COG0252	asparaginase activity
NRZ32_16145	COG1803	Methylglyoxal synthase
NRZ32_16170	COG1444	tRNA N-acetyltransferase activity
NRZ32_16180	COG0835	chemotaxis
NRZ32_16180	COG0784	Response regulator, receiver
NRZ32_16185	COG3314	Sporulation integral membrane protein YlbJ
NRZ32_16220	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NRZ32_16225	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NRZ32_16240	COG0477	Major facilitator Superfamily
NRZ32_16245	COG0523	cobalamin synthesis protein
NRZ32_16255	COG1280	lysine exporter protein (LysE YggA)
NRZ32_16265	COG2200	EAL domain
NRZ32_16270	COG1049	propionate catabolic process, 2-methylcitrate cycle
NRZ32_16275	COG1752	Esterase of the alpha-beta hydrolase superfamily
NRZ32_16280	COG0840	transmembrane signaling receptor activity
NRZ32_16285	COG0840	transmembrane signaling receptor activity
NRZ32_16295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NRZ32_16300	COG0508	dehydrogenase complex catalyzes the overall conversion of
NRZ32_16305	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NRZ32_16310	COG2186	Transcriptional regulator
NRZ32_16335	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NRZ32_16340	COG1459	type II secretion system
NRZ32_16345	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NRZ32_16355	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
NRZ32_16360	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
NRZ32_16365	COG0494	nUDIX hydrolase
NRZ32_16375	COG0653	protein targeting
NRZ32_16385	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NRZ32_16390	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NRZ32_16395	COG0849	cell division
NRZ32_16400	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NRZ32_16405	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NRZ32_16410	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NRZ32_16415	COG0772	Belongs to the SEDS family
NRZ32_16420	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NRZ32_16425	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NRZ32_16430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NRZ32_16440	COG0768	penicillin binding
NRZ32_16445	COG3116	cell division
NRZ32_16450	COG0275	rRNA processing
NRZ32_16455	COG2001	Belongs to the MraZ family
NRZ32_16465	COG1388	LysM domain
NRZ32_16465	COG0741	lytic transglycosylase activity
NRZ32_16470	COG1360	Flagellar Motor Protein
NRZ32_16475	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NRZ32_16480	COG1191	sigma factor activity
NRZ32_16505	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NRZ32_16510	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NRZ32_16530	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NRZ32_16535	COG1256	bacterial-type flagellum assembly
NRZ32_16535	COG4786	Flagellar basal body rod
NRZ32_16545	COG1706	bacterial-type flagellum-dependent cell motility
NRZ32_16550	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
NRZ32_16555	COG4786	Flagellar basal body rod
NRZ32_16565	COG1749	Flagellar hook protein flgE
NRZ32_16580	COG1815	bacterial-type flagellum-dependent cell motility
NRZ32_16615	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NRZ32_16625	COG1677	Flagellar hook-basal body complex protein FliE
NRZ32_16675	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NRZ32_16680	COG3107	peptidoglycan biosynthetic process
NRZ32_16685	COG0792	nuclease activity
NRZ32_16690	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NRZ32_16695	COG2823	Periplasmic or secreted lipoprotein
NRZ32_16700	COG2969	positive regulation of protein catabolic process
NRZ32_16705	COG0625	glutathione transferase activity
NRZ32_16710	COG2857	Cytochrome c1
NRZ32_16715	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NRZ32_16720	COG0723	plastoquinol--plastocyanin reductase activity
NRZ32_16725	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NRZ32_16730	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NRZ32_16735	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NRZ32_16745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NRZ32_16750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NRZ32_16780	COG3964	amidohydrolase
NRZ32_16795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ32_16795	COG3711	transcriptional antiterminator
NRZ32_16800	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ32_16805	COG1660	Displays ATPase and GTPase activities
NRZ32_16810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ32_16820	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NRZ32_16825	COG1137	ATPase activity
NRZ32_16830	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NRZ32_16835	COG3117	lipopolysaccharide transmembrane transporter activity
NRZ32_16840	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NRZ32_16845	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NRZ32_16845	COG0517	IMP dehydrogenase activity
NRZ32_16850	COG1127	ABC transporter
NRZ32_16855	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NRZ32_16860	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NRZ32_16865	COG2854	intermembrane phospholipid transfer
NRZ32_16875	COG5007	Belongs to the BolA IbaG family
NRZ32_16880	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NRZ32_16885	COG0312	modulator of DNA gyrase
NRZ32_16890	COG3028	Belongs to the UPF0307 family
NRZ32_16900	COG2926	Belongs to the UPF0265 family
NRZ32_16930	COG1396	sequence-specific DNA binding
NRZ32_16935	COG3135	benzoate transporter
NRZ32_16960	COG0840	transmembrane signaling receptor activity
NRZ32_16965	COG3047	cAMP biosynthetic process
NRZ32_16975	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NRZ32_16980	COG2197	response regulator
NRZ32_17015	COG4771	TonB-dependent receptor
NRZ32_17020	COG5001	Diguanylate cyclase
NRZ32_17020	COG4251	negative regulation of phosphorylation
NRZ32_17020	COG3706	GGDEF domain
NRZ32_17020	COG2203	Gaf domain
NRZ32_17065	COG0346	lactoylglutathione lyase activity
NRZ32_17075	COG0583	DNA-binding transcription factor activity
NRZ32_17090	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NRZ32_17095	COG1074	ATP-dependent DNA helicase activity
NRZ32_17100	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NRZ32_17105	COG2259	Doxx family
NRZ32_17110	COG1741	Belongs to the pirin family
NRZ32_17120	COG0583	DNA-binding transcription factor activity
NRZ32_17145	COG1175	transmembrane transport
NRZ32_17155	COG3842	ATPase activity
NRZ32_17165	COG3706	GGDEF domain
NRZ32_17185	COG0454	-acetyltransferase
NRZ32_17185	COG0456	acetyltransferase
NRZ32_17210	COG0671	phosphoesterase, PA-phosphatase related
NRZ32_17215	COG0628	permease
NRZ32_17220	COG4221	oxidoreductase activity
NRZ32_17225	COG3284	Transcriptional regulator
NRZ32_17240	COG1461	Dihydroxyacetone kinase
NRZ32_17245	COG2376	Dihydroxyacetone kinase
NRZ32_17250	COG2252	PERMEase
NRZ32_17285	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NRZ32_17290	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NRZ32_17295	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NRZ32_17300	COG0049	tRNA binding
NRZ32_17305	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NRZ32_17310	COG2168	tRNA wobble position uridine thiolation
NRZ32_17315	COG2923	Belongs to the DsrF TusC family
NRZ32_17325	COG0251	oxidation-reduction process
NRZ32_17330	COG2964	Protein conserved in bacteria
NRZ32_17335	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NRZ32_17340	COG0085	RNA polymerase activity
NRZ32_17345	COG0222	ribosome binding
NRZ32_17350	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NRZ32_17355	COG0081	regulation of translation
NRZ32_17360	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NRZ32_17365	COG0250	Participates in transcription elongation, termination and antitermination
NRZ32_17380	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NRZ32_17405	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NRZ32_17410	COG0569	domain protein
NRZ32_17415	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NRZ32_17435	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NRZ32_17440	COG3005	denitrification pathway
NRZ32_17445	COG0243	molybdopterin cofactor binding
NRZ32_17475	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
NRZ32_17490	COG2204	response regulator
NRZ32_17500	COG2205	protein histidine kinase activity
NRZ32_17515	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ32_17520	COG0516	GMP reductase activity
NRZ32_17520	COG0517	IMP dehydrogenase activity
NRZ32_17525	COG5413	integral membrane protein
NRZ32_17535	COG1522	sequence-specific DNA binding
NRZ32_17540	COG2502	aspartate--ammonia ligase
NRZ32_17545	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NRZ32_17550	COG0542	response to heat
NRZ32_17560	COG0564	pseudouridine synthase activity
NRZ32_17565	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NRZ32_17570	COG0446	pyridine nucleotide-disulphide oxidoreductase
NRZ32_17580	COG3681	Belongs to the UPF0597 family
NRZ32_17590	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NRZ32_17595	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NRZ32_17600	COG1979	alcohol dehydrogenase
NRZ32_17605	COG2207	Transcriptional regulator
NRZ32_17610	COG3040	lipid binding
NRZ32_17625	COG0688	phosphatidylethanolamine metabolic process
NRZ32_17640	COG0540	Belongs to the ATCase OTCase family
NRZ32_17645	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
NRZ32_17650	COG1438	arginine binding
NRZ32_17655	COG1288	antiporter activity
NRZ32_17660	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NRZ32_17710	COG3250	beta-galactosidase activity
NRZ32_17715	COG1609	Transcriptional regulator
NRZ32_17720	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NRZ32_17730	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NRZ32_17735	COG2017	converts alpha-aldose to the beta-anomer
NRZ32_17740	COG0667	Aldo Keto reductase
NRZ32_17745	COG1968	undecaprenyl-diphosphatase activity
NRZ32_17750	COG3806	Anti-sigma factor
NRZ32_17755	COG1595	DNA-templated transcription, initiation
NRZ32_17775	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NRZ32_17780	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NRZ32_17785	COG0477	Major facilitator Superfamily
NRZ32_17795	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NRZ32_17805	COG2116	formate transmembrane transporter activity
NRZ32_17810	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NRZ32_17810	COG1648	precorrin-2 dehydrogenase activity
NRZ32_17815	COG2239	Acts as a magnesium transporter
NRZ32_17825	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NRZ32_17830	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NRZ32_17850	COG0514	ATP-dependent DNA helicase (RecQ)
NRZ32_17855	COG2050	protein possibly involved in aromatic compounds catabolism
NRZ32_17870	COG2258	MOSC domain
NRZ32_17875	COG1177	transmembrane transport
NRZ32_17880	COG1176	ABC-type spermidine putrescine transport system, permease component I
NRZ32_17885	COG3842	ATPase activity
NRZ32_17905	COG0174	glutamine synthetase
NRZ32_17925	COG3045	CreA protein
NRZ32_17930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NRZ32_17935	COG0443	Heat shock 70 kDa protein
NRZ32_17940	COG3187	Heat shock protein
NRZ32_17950	COG0366	Alpha amylase catalytic
NRZ32_17955	COG1086	Polysaccharide biosynthesis protein
NRZ32_17960	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NRZ32_18000	COG1216	Glycosyl transferase, family 2
NRZ32_18015	COG1215	transferase activity, transferring glycosyl groups
NRZ32_18030	COG0318	PFAM AMP-dependent synthetase and ligase
NRZ32_18035	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ32_18050	COG1083	cytidylyl-transferase
NRZ32_18060	COG2089	acid synthase
NRZ32_18080	COG4310	Domain of unknown function (DUF2172)
NRZ32_18115	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NRZ32_18120	COG0745	RESPONSE REGULATOR receiver
NRZ32_18125	COG2205	protein histidine kinase activity
NRZ32_18135	COG0281	malic enzyme
NRZ32_18140	COG0702	epimerase
NRZ32_18145	COG0254	rRNA binding
NRZ32_18150	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NRZ32_18180	COG0129	dihydroxy-acid dehydratase activity
NRZ32_18190	COG3978	acetolactate synthase activity
NRZ32_18200	COG0606	chelatase, subunit chli
NRZ32_18205	COG0204	Acyl-transferase
NRZ32_18210	COG0204	Acyl-transferase
NRZ32_18215	COG1683	Conserved Protein
NRZ32_18225	COG1335	isochorismatase
NRZ32_18235	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
NRZ32_18240	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NRZ32_18245	COG3639	organic phosphonate transmembrane transporter activity
NRZ32_18250	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NRZ32_18255	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NRZ32_18265	COG3084	Protein conserved in bacteria
NRZ32_18270	COG2203	Gaf domain
NRZ32_18270	COG3706	GGDEF domain
NRZ32_18270	COG4251	negative regulation of phosphorylation
NRZ32_18270	COG5001	Diguanylate cyclase
NRZ32_18275	COG0789	Transcriptional regulator
NRZ32_18285	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NRZ32_18290	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NRZ32_18295	COG1561	YicC-like family, N-terminal region
NRZ32_18310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NRZ32_18320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NRZ32_18330	COG1132	(ABC) transporter
NRZ32_18330	COG2375	cellular response to nickel ion
NRZ32_18335	COG1132	(ABC) transporter
NRZ32_18340	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ32_18345	COG4605	iron ion homeostasis
NRZ32_18350	COG4604	ABC transporter, ATP-binding protein
NRZ32_18355	COG4607	ABC-type enterochelin transport system periplasmic component
NRZ32_18360	COG4774	siderophore transport
NRZ32_18380	COG3306	glycosyltransferase involved in LPS biosynthesis
NRZ32_18395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NRZ32_18410	COG1063	alcohol dehydrogenase
NRZ32_18415	COG3245	cytochrome
NRZ32_18420	COG5001	Diguanylate cyclase
NRZ32_18420	COG3300	MHYT domain
NRZ32_18430	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NRZ32_18435	COG2166	iron-sulfur cluster assembly
NRZ32_18440	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NRZ32_18475	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NRZ32_18480	COG4206	TonB-dependent receptor
NRZ32_18485	COG0583	DNA-binding transcription factor activity
NRZ32_18500	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NRZ32_18505	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NRZ32_18510	COG2223	nitrite transmembrane transporter activity
NRZ32_18515	COG3279	Response regulator of the LytR AlgR family
NRZ32_18520	COG3275	phosphorelay sensor kinase activity
NRZ32_18530	COG2223	nitrite transmembrane transporter activity
NRZ32_18535	COG2081	HI0933 family
NRZ32_18540	COG1528	Iron-storage protein
NRZ32_18550	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NRZ32_18555	COG0589	response to stress
NRZ32_18595	COG3642	lipopolysaccharide core region biosynthetic process
NRZ32_18600	COG0859	PFAM glycosyl transferase family 9
NRZ32_18610	COG1758	RNA polymerase activity
NRZ32_18615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NRZ32_18620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NRZ32_18630	COG2267	carboxylic ester hydrolase activity
NRZ32_18635	COG0561	phosphatase activity
NRZ32_18655	COG2271	Major facilitator Superfamily
NRZ32_18690	COG1309	transcriptional regulator
NRZ32_18695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NRZ32_18700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRZ32_18705	COG4191	Histidine kinase
NRZ32_18705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ32_18710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NRZ32_18735	COG2205	protein histidine kinase activity
NRZ32_18740	COG0745	RESPONSE REGULATOR receiver
NRZ32_18745	COG2814	Major facilitator Superfamily
NRZ32_18760	COG3977	Valine--pyruvate aminotransferase
NRZ32_18765	COG0071	Belongs to the small heat shock protein (HSP20) family
NRZ32_18770	COG0071	Belongs to the small heat shock protein (HSP20) family
NRZ32_18775	COG2378	regulation of single-species biofilm formation
NRZ32_18795	COG0592	DNA-directed DNA polymerase activity
NRZ32_18800	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NRZ32_18815	COG1126	abc transporter atp-binding protein
NRZ32_18820	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NRZ32_18825	COG0594	ribonuclease P activity
NRZ32_18830	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NRZ32_18835	COG0706	membrane insertase activity
NRZ32_18840	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NRZ32_18855	COG1120	ATPase activity
NRZ32_18860	COG4615	Cyclic peptide transporter
NRZ32_18865	COG4774	siderophore transport
NRZ32_18870	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NRZ32_18875	COG0445	tRNA wobble uridine modification
NRZ32_18880	COG0357	Ribosomal RNA small subunit methyltransferase G
NRZ32_18885	COG1192	Involved in chromosome partitioning
NRZ32_18890	COG1475	DNA binding
NRZ32_18900	COG0356	it plays a direct role in the translocation of protons across the membrane
NRZ32_18910	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NRZ32_18915	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NRZ32_18920	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NRZ32_18925	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NRZ32_18930	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NRZ32_18935	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NRZ32_18940	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NRZ32_18945	COG4452	Inner membrane protein CreD
NRZ32_18965	COG0745	RESPONSE REGULATOR receiver
NRZ32_18975	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NRZ32_18980	COG2771	luxR family
NRZ32_18995	COG0811	peptide transport
NRZ32_19000	COG0848	biopolymer transport protein
NRZ32_19005	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NRZ32_19050	COG0402	S-adenosylhomocysteine deaminase activity
NRZ32_19055	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NRZ32_19065	COG3165	ubiquinone biosynthetic process from chorismate
NRZ32_19070	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NRZ32_19080	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NRZ32_19085	COG0805	protein transport
NRZ32_19090	COG0084	hydrolase, TatD family'
NRZ32_19110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ32_19115	COG0742	ribosomal rna small subunit methyltransferase
NRZ32_19130	COG0248	Ppx GppA phosphatase
NRZ32_19135	COG0513	Belongs to the DEAD box helicase family
NRZ32_19140	COG3118	belongs to the thioredoxin family
NRZ32_19155	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NRZ32_19180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRZ32_19220	COG1609	Transcriptional regulator
NRZ32_19235	COG2188	Transcriptional regulator
NRZ32_19240	COG3604	Transcriptional regulator
NRZ32_19245	COG1773	rubredoxin
NRZ32_19245	COG0426	domain, Protein
NRZ32_19250	COG0446	pyridine nucleotide-disulphide oxidoreductase
NRZ32_19260	COG0348	domain, Protein
NRZ32_19265	COG0814	amino acid
NRZ32_19290	COG2046	Belongs to the sulfate adenylyltransferase family
NRZ32_19290	COG0529	Catalyzes the synthesis of activated sulfate
NRZ32_19305	COG0751	glycine-tRNA ligase activity
NRZ32_19310	COG0752	glycyl-tRNA synthetase alpha subunit
NRZ32_19315	COG2818	Glycosylase
NRZ32_19320	COG1335	isochorismatase
NRZ32_19325	COG2885	chlorophyll binding
NRZ32_19330	COG0251	oxidation-reduction process
NRZ32_19335	COG0425	Belongs to the sulfur carrier protein TusA family
NRZ32_19360	COG0183	Belongs to the thiolase family
NRZ32_19365	COG1024	Enoyl-CoA hydratase
NRZ32_19365	COG1250	3-hydroxyacyl-CoA dehydrogenase
NRZ32_19370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NRZ32_19375	COG0006	proline dipeptidase activity
NRZ32_19380	COG1739	Uncharacterized protein family UPF0029
NRZ32_19385	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NRZ32_19390	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
NRZ32_19415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ32_19415	COG1042	CoA-binding domain protein
NRZ32_19415	COG0045	succinate-CoA ligase (ADP-forming) activity
NRZ32_19430	COG0583	DNA-binding transcription factor activity
NRZ32_19435	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NRZ32_19440	COG0166	Belongs to the GPI family
NRZ32_19450	COG0668	transmembrane transport
NRZ32_19455	COG1309	transcriptional regulator
NRZ32_19460	COG0756	dUTP diphosphatase activity
NRZ32_19465	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NRZ32_19470	COG2003	Belongs to the UPF0758 family
NRZ32_19475	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NRZ32_19480	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NRZ32_19490	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NRZ32_19495	COG2990	Protein conserved in bacteria
NRZ32_19500	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NRZ32_19505	COG0859	PFAM glycosyl transferase family 9
NRZ32_19510	COG0463	Glycosyl transferase, family 2
NRZ32_19515	COG0859	PFAM glycosyl transferase family 9
NRZ32_19520	COG1519	Transferase
NRZ32_19540	COG1609	Transcriptional regulator
NRZ32_19545	COG0604	alcohol dehydrogenase
NRZ32_19565	COG1580	Controls the rotational direction of flagella during chemotaxis
NRZ32_19570	COG3161	chorismate lyase activity
NRZ32_19575	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NRZ32_19580	COG2937	Belongs to the GPAT DAPAT family
NRZ32_19585	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NRZ32_19600	COG0534	Mate efflux family protein
NRZ32_19605	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NRZ32_19610	COG2205	protein histidine kinase activity
NRZ32_19615	COG0745	RESPONSE REGULATOR receiver
NRZ32_19625	COG1045	serine acetyltransferase
NRZ32_19635	COG3074	FtsZ-dependent cytokinesis
NRZ32_19640	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
NRZ32_19645	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NRZ32_19645	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NRZ32_19650	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NRZ32_19685	COG1609	Transcriptional regulator
NRZ32_19690	COG3250	beta-galactosidase activity
NRZ32_19695	COG2731	YhcH YjgK YiaL family protein
NRZ32_19700	COG0531	amino acid
NRZ32_19705	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRZ32_19710	COG0531	amino acid
NRZ32_19715	COG0385	Bile acid
NRZ32_19720	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NRZ32_19740	COG0583	DNA-binding transcription factor activity
NRZ32_19745	COG1079	Belongs to the binding-protein-dependent transport system permease family
NRZ32_19750	COG4603	Belongs to the binding-protein-dependent transport system permease family
NRZ32_19755	COG3845	ABC transporter
NRZ32_19760	COG1744	ABC transporter substrate-binding protein PnrA-like
NRZ32_19765	COG0210	DNA helicase
NRZ32_19770	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NRZ32_19780	COG1943	Transposase
NRZ32_19800	COG0583	DNA-binding transcription factor activity
NRZ32_19830	COG3161	chorismate lyase activity
NRZ32_19865	COG1280	lysine exporter protein (LysE YggA)
NRZ32_19875	COG2391	methyltransferase activity
NRZ32_19885	COG1280	lysine exporter protein (LysE YggA)
NRZ32_19895	COG2962	Rard protein
NRZ32_19905	COG1012	belongs to the aldehyde dehydrogenase family
NRZ32_19910	COG1396	sequence-specific DNA binding
NRZ32_19915	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NRZ32_19925	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NRZ32_19925	COG0519	Catalyzes the synthesis of GMP from XMP
NRZ32_19930	COG0686	Belongs to the AlaDH PNT family
NRZ32_19935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRZ32_19955	COG1322	Protein conserved in bacteria
NRZ32_19960	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NRZ32_19965	COG0569	domain protein
NRZ32_19970	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NRZ32_19970	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NRZ32_19975	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NRZ32_19980	COG0242	peptide deformylase activity
NRZ32_19990	COG0758	DNA mediated transformation
NRZ32_19995	COG2922	Belongs to the Smg family
NRZ32_20000	COG0551	DNA topoisomerase type I activity
NRZ32_20010	COG0009	L-threonylcarbamoyladenylate synthase
NRZ32_20015	COG0408	coproporphyrinogen oxidase activity
NRZ32_20020	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NRZ32_20030	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NRZ32_20040	COG3078	GTPase activator activity
NRZ32_20055	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NRZ32_20060	COG2204	response regulator
NRZ32_20065	COG3852	Histidine kinase
NRZ32_20075	COG0174	glutamine synthetase
NRZ32_20080	COG1217	gtp-binding protein TYPA
NRZ32_20085	COG1295	ribonuclease BN
NRZ32_20090	COG1490	D-aminoacyl-tRNA deacylase activity
NRZ32_20100	COG0456	acetyltransferase
NRZ32_20110	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NRZ32_20115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRZ32_20120	COG2610	gluconate transmembrane transporter activity
NRZ32_20125	COG3265	gluconokinase activity
NRZ32_20130	COG0129	dihydroxy-acid dehydratase activity
NRZ32_20135	COG0800	Aldolase
NRZ32_20140	COG1609	Transcriptional regulator
NRZ32_20150	COG4942	peptidase
NRZ32_20155	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NRZ32_20160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRZ32_20165	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
NRZ32_20170	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NRZ32_20175	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NRZ32_20175	COG0316	Belongs to the HesB IscA family
NRZ32_20180	COG1040	competence protein
NRZ32_20185	COG0596	Alpha beta hydrolase
NRZ32_20205	COG2183	response to ionizing radiation
NRZ32_20210	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NRZ32_20230	COG0051	transcription antitermination factor activity, RNA binding
NRZ32_20235	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NRZ32_20240	COG0088	Forms part of the polypeptide exit tunnel
NRZ32_20245	COG0089	rRNA binding
NRZ32_20250	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NRZ32_20255	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NRZ32_20260	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NRZ32_20265	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NRZ32_20270	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NRZ32_20275	COG0255	Belongs to the universal ribosomal protein uL29 family
NRZ32_20280	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NRZ32_20285	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NRZ32_20290	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NRZ32_20295	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NRZ32_20300	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NRZ32_20305	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NRZ32_20310	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NRZ32_20315	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NRZ32_20320	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NRZ32_20325	COG1841	ribosomal large subunit assembly
NRZ32_20330	COG0200	Binds to the 23S rRNA
NRZ32_20335	COG0201	protein transport
NRZ32_20340	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NRZ32_20345	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NRZ32_20350	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NRZ32_20355	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NRZ32_20360	COG0202	RNA polymerase activity
NRZ32_20365	COG0203	ribosomal protein L17
NRZ32_20415	COG2249	NAD(P)H dehydrogenase (quinone) activity
NRZ32_20420	COG0583	DNA-binding transcription factor activity
NRZ32_20425	COG4221	oxidoreductase activity
NRZ32_20440	COG1770	oligopeptidase
NRZ32_20445	COG2358	TRAP transporter, solute receptor (TAXI family
NRZ32_20460	COG3714	YhhN family
NRZ32_20485	COG1301	dicarboxylic acid transport
NRZ32_20495	COG2095	MarC family integral membrane protein
NRZ32_20505	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NRZ32_20515	COG0741	lytic transglycosylase activity
NRZ32_20525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRZ32_20550	COG0742	ribosomal rna small subunit methyltransferase
NRZ32_20555	COG0552	protein localization to endoplasmic reticulum
NRZ32_20560	COG2884	Cell division ATP-binding protein ftsE
NRZ32_20565	COG2177	Part of the ABC transporter FtsEX involved in
NRZ32_20575	COG0288	reversible hydration of carbon dioxide
NRZ32_20580	COG2188	Transcriptional regulator
NRZ32_20585	COG1228	amidohydrolase
NRZ32_20590	COG0010	Belongs to the arginase family
NRZ32_20595	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NRZ32_20600	COG2986	histidine ammonia-lyase
NRZ32_20605	COG0387	Pfam Sodium calcium exchanger
NRZ32_20610	COG2200	EAL domain
NRZ32_20615	COG2199	diguanylate cyclase activity
NRZ32_20615	COG2200	EAL domain
NRZ32_20650	COG2842	Transposition protein
NRZ32_20660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NRZ32_20665	COG1459	type II secretion system
NRZ32_20675	COG2165	general secretion pathway protein
NRZ32_20710	COG1077	Cell shape determining protein MreB Mrl
NRZ32_20715	COG1792	Involved in formation and maintenance of cell shape
NRZ32_20720	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NRZ32_20725	COG0424	maF-like protein
NRZ32_20730	COG1530	ribonuclease E activity
NRZ32_20735	COG3164	Protein of unknown function
NRZ32_20750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NRZ32_20755	COG0312	modulator of DNA gyrase
NRZ32_20770	COG0477	Major facilitator Superfamily
NRZ32_20780	COG3437	response regulator, receiver
NRZ32_20785	COG0784	Response regulator, receiver
NRZ32_20785	COG2205	protein histidine kinase activity
NRZ32_20785	COG5002	protein histidine kinase activity
NRZ32_20795	COG1366	Belongs to the anti-sigma-factor antagonist family
NRZ32_20815	COG3700	Belongs to the class B bacterial acid phosphatase family
NRZ32_20820	COG2321	neutral zinc metallopeptidase
NRZ32_20830	COG1639	'signal transduction protein
NRZ32_20855	COG0189	ligase activity
NRZ32_20860	COG0642	Histidine kinase
NRZ32_20865	COG0745	RESPONSE REGULATOR receiver
NRZ32_20885	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NRZ32_20890	COG0352	thiamine-phosphate diphosphorylase activity
NRZ32_20895	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NRZ32_20905	COG2022	thiamine diphosphate biosynthetic process
NRZ32_20910	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NRZ32_20915	COG2801	Transposase and inactivated derivatives
NRZ32_20935	COG0110	maltose O-acetyltransferase activity
NRZ32_20940	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
NRZ32_20960	COG0814	amino acid
NRZ32_20965	COG3932	Exopolysaccharide synthesis, ExoD
NRZ32_20985	COG1733	regulation of RNA biosynthetic process
NRZ32_21025	COG1494	fructose-1,6-bisphosphatase
NRZ32_21040	COG2959	enzyme of heme biosynthesis
NRZ32_21050	COG0181	hydroxymethylbilane synthase activity
NRZ32_21055	COG3072	Adenylate cyclase
NRZ32_21060	COG0400	carboxylic ester hydrolase activity
NRZ32_21065	COG1965	Belongs to the frataxin family
NRZ32_21075	COG0019	diaminopimelate decarboxylase activity
NRZ32_21080	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NRZ32_21095	COG1011	Hydrolase
NRZ32_21115	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NRZ32_21120	COG0561	phosphatase activity
NRZ32_21135	COG0842	Transport permease protein
NRZ32_21135	COG1129	ABC transporter
NRZ32_21145	COG1058	Belongs to the CinA family
NRZ32_21145	COG1546	Belongs to the CinA family
NRZ32_21150	COG1418	mRNA catabolic process
NRZ32_21155	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NRZ32_21165	COG1522	sequence-specific DNA binding
NRZ32_21170	COG1368	sulfuric ester hydrolase activity
NRZ32_21190	COG1285	pathogenesis
NRZ32_21210	COG4221	oxidoreductase activity
NRZ32_21225	COG1979	alcohol dehydrogenase
NRZ32_21235	COG2873	o-acetylhomoserine
NRZ32_21260	COG5380	lipid catabolic process
NRZ32_21265	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NRZ32_21280	COG2949	membrane
NRZ32_21285	COG3291	Pkd domain containing protein